LOCUS       DAXLPQ010000001       138734 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.001, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000001 DAXLPQ010000000
VERSION     DAXLPQ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 138734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 138734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..138734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.001"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..314
                     /locus_tag="ACF3UO_000001"
     CDS             <1..314
                     /locus_tag="ACF3UO_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFD3656067.1"
                     /translation="LVLYPREILYIESIKGLKNQVMVKTTTEDKLVNTSLKQLKTELE
                     KYAYFLLLKSYCINLSQLQKIDSAHYVLEFFNGDSLLVGRKIFEKTKERFHDFQKTAS
                     S"
     gene            complement(400..1158)
                     /locus_tag="ACF3UO_000002"
     CDS             complement(400..1158)
                     /locus_tag="ACF3UO_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFD3656068.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(1155..1619)
                     /locus_tag="ACF3UO_000003"
                     /pseudo
     CDS             complement(1155..1619)
                     /locus_tag="ACF3UO_000003"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            complement(1638..2135)
                     /locus_tag="ACF3UO_000004"
     CDS             complement(1638..2135)
                     /locus_tag="ACF3UO_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFD3656069.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            complement(2203..5370)
                     /locus_tag="ACF3UO_000005"
     CDS             complement(2203..5370)
                     /locus_tag="ACF3UO_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFD3656070.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(5594..6478)
                     /locus_tag="ACF3UO_000006"
     CDS             complement(5594..6478)
                     /locus_tag="ACF3UO_000006"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3656071.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(6573..7010)
                     /locus_tag="ACF3UO_000007"
     CDS             complement(6573..7010)
                     /locus_tag="ACF3UO_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656072.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(7227..8138)
                     /locus_tag="ACF3UO_000008"
     CDS             complement(7227..8138)
                     /locus_tag="ACF3UO_000008"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3656073.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(8595..9023)
                     /locus_tag="ACF3UO_000009"
     CDS             complement(8595..9023)
                     /locus_tag="ACF3UO_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656074.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(9051..9689)
                     /locus_tag="ACF3UO_000010"
     CDS             complement(9051..9689)
                     /locus_tag="ACF3UO_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656075.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(9693..11729)
                     /locus_tag="ACF3UO_000011"
     CDS             complement(9693..11729)
                     /locus_tag="ACF3UO_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFD3656076.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            11855..12520
                     /locus_tag="ACF3UO_000012"
     CDS             11855..12520
                     /locus_tag="ACF3UO_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656077.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(13960..18357)
                     /locus_tag="ACF3UO_000013"
     CDS             complement(13960..18357)
                     /locus_tag="ACF3UO_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HFD3656078.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDRMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
     gene            complement(18335..19120)
                     /locus_tag="ACF3UO_000014"
     CDS             complement(18335..19120)
                     /locus_tag="ACF3UO_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HFD3656079.1"
                     /translation="MVEDMVMVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGI
                     KEACEELQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGV
                     ELLEDNAQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKR
                     TPDDNPIIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLD
                     LFSFDDEVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            complement(20876..21652)
                     /locus_tag="ACF3UO_000015"
     CDS             complement(20876..21652)
                     /locus_tag="ACF3UO_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656080.1"
                     /translation="MMKKNYLKTGIFLVIGTILVIQLSGCRNKDKDFYGYWSGTAEKI
                     PVDYNFKITKDRVIELQKNGEMVDFKYTLRHKKFDSTTFRSIMISKDELVKAIPELKE
                     TTGISNITFMPIDGEKDKLTVLVNLDEHLSTATLYRTTKDESPIGKVEKKNDTISRQT
                     VDKKIDTFIKTYAAIPPTWKLVNEDKGITINTDTEIPTDAQSLSDLLANLTGVSNAVS
                     EQVGKDIPLRLLENGKKDYSVVFKNGKVTDYNEIFEKVIE"
     gene            complement(21853..22179)
                     /locus_tag="ACF3UO_000016"
     CDS             complement(21853..22179)
                     /locus_tag="ACF3UO_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656081.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(22225..22587)
                     /locus_tag="ACF3UO_000017"
     CDS             complement(22225..22587)
                     /locus_tag="ACF3UO_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFD3656082.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(22624..22839)
                     /locus_tag="ACF3UO_000018"
     CDS             complement(22624..22839)
                     /locus_tag="ACF3UO_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3656083.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            22965..23300
                     /locus_tag="ACF3UO_000019"
     CDS             22965..23300
                     /locus_tag="ACF3UO_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3656084.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(23376..25373)
                     /locus_tag="ACF3UO_000020"
     CDS             complement(23376..25373)
                     /locus_tag="ACF3UO_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656085.1"
                     /translation="METPMINIPINVDKERLLEKPVIEDEKKRIRKRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNKSEEFLETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKALSINLVHNSAFAIQKSIRYSENLEKFKIVFLLKEAITDYSKMIAVYEYLKKI
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHDDHNPSASIFTSKTGHSIFYCHSSNCGISENFIGVVMLILEKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMEDKLFRTINNYLEEMRRVYDALLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKWNKLLSFMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLKKVHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNFRSELSKEKQLILDEAHEVLQDLSWQGTYLMTEKELINTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELIASGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(25471..25746)
                     /locus_tag="ACF3UO_000021"
     CDS             complement(25471..25746)
                     /locus_tag="ACF3UO_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656086.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMEQYKG"
     gene            25981..26715
                     /locus_tag="ACF3UO_000022"
     CDS             25981..26715
                     /locus_tag="ACF3UO_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3656087.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            26754..27896
                     /locus_tag="ACF3UO_000023"
     CDS             26754..27896
                     /locus_tag="ACF3UO_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3656088.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(27991..29382)
                     /gene="sufB"
                     /locus_tag="ACF3UO_000024"
     CDS             complement(27991..29382)
                     /gene="sufB"
                     /locus_tag="ACF3UO_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFD3656089.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKAVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(29387..29857)
                     /gene="sufU"
                     /locus_tag="ACF3UO_000025"
     CDS             complement(29387..29857)
                     /gene="sufU"
                     /locus_tag="ACF3UO_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFD3656090.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(29844..31079)
                     /locus_tag="ACF3UO_000026"
     CDS             complement(29844..31079)
                     /locus_tag="ACF3UO_000026"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFD3656091.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(31076..32362)
                     /gene="sufD"
                     /locus_tag="ACF3UO_000027"
     CDS             complement(31076..32362)
                     /gene="sufD"
                     /locus_tag="ACF3UO_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFD3656092.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(32375..33148)
                     /gene="sufC"
                     /locus_tag="ACF3UO_000028"
     CDS             complement(32375..33148)
                     /gene="sufC"
                     /locus_tag="ACF3UO_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFD3656093.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(33345..34193)
                     /locus_tag="ACF3UO_000029"
     CDS             complement(33345..34193)
                     /locus_tag="ACF3UO_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3656094.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(34217..34903)
                     /locus_tag="ACF3UO_000030"
     CDS             complement(34217..34903)
                     /locus_tag="ACF3UO_000030"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFD3656095.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(34896..35930)
                     /locus_tag="ACF3UO_000031"
     CDS             complement(34896..35930)
                     /locus_tag="ACF3UO_000031"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFD3656096.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(35993..36249)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(36325..36663)
                     /locus_tag="ACF3UO_000032"
     CDS             complement(36325..36663)
                     /locus_tag="ACF3UO_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFD3656097.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(36665..37021)
                     /locus_tag="ACF3UO_000033"
     CDS             complement(36665..37021)
                     /locus_tag="ACF3UO_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFD3656098.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(37027..38214)
                     /locus_tag="ACF3UO_000034"
     CDS             complement(37027..38214)
                     /locus_tag="ACF3UO_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFD3656099.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(38405..39250)
                     /locus_tag="ACF3UO_000035"
     CDS             complement(38405..39250)
                     /locus_tag="ACF3UO_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3656100.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            39484..40449
                     /locus_tag="ACF3UO_000036"
     CDS             39484..40449
                     /locus_tag="ACF3UO_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFD3656101.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            40826..41869
                     /locus_tag="ACF3UO_000037"
     CDS             40826..41869
                     /locus_tag="ACF3UO_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFD3656102.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(41931..42395)
                     /locus_tag="ACF3UO_000038"
     CDS             complement(41931..42395)
                     /locus_tag="ACF3UO_000038"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFD3656103.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            42641..43588
                     /locus_tag="ACF3UO_000039"
     CDS             42641..43588
                     /locus_tag="ACF3UO_000039"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3656104.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(43799..45871)
                     /locus_tag="ACF3UO_000040"
     CDS             complement(43799..45871)
                     /locus_tag="ACF3UO_000040"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFD3656105.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(45804..46181)
                     /locus_tag="ACF3UO_000041"
     CDS             complement(45804..46181)
                     /locus_tag="ACF3UO_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFD3656106.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(46310..46870)
                     /locus_tag="ACF3UO_000042"
     CDS             complement(46310..46870)
                     /locus_tag="ACF3UO_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3656107.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            47020..48312
                     /locus_tag="ACF3UO_000043"
     CDS             47020..48312
                     /locus_tag="ACF3UO_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFD3656108.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(48372..49490)
                     /locus_tag="ACF3UO_000044"
     CDS             complement(48372..49490)
                     /locus_tag="ACF3UO_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFD3656109.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(49504..50925)
                     /gene="arcD"
                     /locus_tag="ACF3UO_000045"
     CDS             complement(49504..50925)
                     /gene="arcD"
                     /locus_tag="ACF3UO_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFD3656110.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(51171..52292)
                     /gene="mnmA"
                     /locus_tag="ACF3UO_000046"
     CDS             complement(51171..52292)
                     /gene="mnmA"
                     /locus_tag="ACF3UO_000046"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFD3656111.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLIYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            52696..53295
                     /locus_tag="ACF3UO_000047"
     CDS             52696..53295
                     /locus_tag="ACF3UO_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3656112.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(53433..54719)
                     /gene="efmA"
                     /locus_tag="ACF3UO_000048"
     CDS             complement(53433..54719)
                     /gene="efmA"
                     /locus_tag="ACF3UO_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFD3656113.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(54990..55334)
                     /locus_tag="ACF3UO_000049"
     CDS             complement(54990..55334)
                     /locus_tag="ACF3UO_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFD3656114.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(55471..56616)
                     /locus_tag="ACF3UO_000050"
     CDS             complement(55471..56616)
                     /locus_tag="ACF3UO_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD3656115.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(56796..57770)
                     /locus_tag="ACF3UO_000051"
     CDS             complement(56796..57770)
                     /locus_tag="ACF3UO_000051"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD3656116.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(57850..58725)
                     /locus_tag="ACF3UO_000052"
     CDS             complement(57850..58725)
                     /locus_tag="ACF3UO_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFD3656117.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            58855..60762
                     /locus_tag="ACF3UO_000053"
     CDS             58855..60762
                     /locus_tag="ACF3UO_000053"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFD3656118.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(61303..64581)
                     /locus_tag="ACF3UO_000054"
     CDS             complement(61303..64581)
                     /locus_tag="ACF3UO_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFD3656119.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(64852..65397)
                     /locus_tag="ACF3UO_000055"
     CDS             complement(64852..65397)
                     /locus_tag="ACF3UO_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFD3656120.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(65409..66101)
                     /locus_tag="ACF3UO_000056"
     CDS             complement(65409..66101)
                     /locus_tag="ACF3UO_000056"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFD3656121.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(66120..66404)
                     /gene="macP"
                     /locus_tag="ACF3UO_000057"
     CDS             complement(66120..66404)
                     /gene="macP"
                     /locus_tag="ACF3UO_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFD3656122.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(66417..66980)
                     /locus_tag="ACF3UO_000058"
     CDS             complement(66417..66980)
                     /locus_tag="ACF3UO_000058"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFD3656123.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            67208..67870
                     /locus_tag="ACF3UO_000059"
     CDS             67208..67870
                     /locus_tag="ACF3UO_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFD3656124.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            67994..69190
                     /locus_tag="ACF3UO_000060"
     CDS             67994..69190
                     /locus_tag="ACF3UO_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFD3656125.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(69291..70667)
                     /locus_tag="ACF3UO_000061"
     CDS             complement(69291..70667)
                     /locus_tag="ACF3UO_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3656126.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(70704..71570)
                     /locus_tag="ACF3UO_000062"
     CDS             complement(70704..71570)
                     /locus_tag="ACF3UO_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFD3656127.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(71659..72684)
                     /locus_tag="ACF3UO_000063"
     CDS             complement(71659..72684)
                     /locus_tag="ACF3UO_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3656128.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(72702..73376)
                     /locus_tag="ACF3UO_000064"
     CDS             complement(72702..73376)
                     /locus_tag="ACF3UO_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3656129.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(73560..74453)
                     /locus_tag="ACF3UO_000065"
     CDS             complement(73560..74453)
                     /locus_tag="ACF3UO_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3656130.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(74527..76224)
                     /locus_tag="ACF3UO_000066"
     CDS             complement(74527..76224)
                     /locus_tag="ACF3UO_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3656131.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(76217..77530)
                     /locus_tag="ACF3UO_000067"
     CDS             complement(76217..77530)
                     /locus_tag="ACF3UO_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFD3656132.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(77530..81799)
                     /locus_tag="ACF3UO_000068"
                     /pseudo
     CDS             complement(77530..81799)
                     /locus_tag="ACF3UO_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333417.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
     gene            complement(82096..82614)
                     /locus_tag="ACF3UO_000069"
     CDS             complement(82096..82614)
                     /locus_tag="ACF3UO_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD3656133.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(82616..83233)
                     /locus_tag="ACF3UO_000070"
     CDS             complement(82616..83233)
                     /locus_tag="ACF3UO_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFD3656134.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(83230..84084)
                     /locus_tag="ACF3UO_000071"
     CDS             complement(83230..84084)
                     /locus_tag="ACF3UO_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3656135.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(84081..84992)
                     /locus_tag="ACF3UO_000072"
     CDS             complement(84081..84992)
                     /locus_tag="ACF3UO_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3656136.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(85033..86367)
                     /locus_tag="ACF3UO_000073"
     CDS             complement(85033..86367)
                     /locus_tag="ACF3UO_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3656137.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            86575..87405
                     /locus_tag="ACF3UO_000074"
     CDS             86575..87405
                     /locus_tag="ACF3UO_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFD3656138.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(87649..87898)
                     /locus_tag="ACF3UO_000075"
                     /pseudo
     CDS             complement(87649..87898)
                     /locus_tag="ACF3UO_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(88089..88283)
                     /locus_tag="ACF3UO_000076"
     CDS             complement(88089..88283)
                     /locus_tag="ACF3UO_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656139.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(88788..88973)
                     /locus_tag="ACF3UO_000077"
     CDS             complement(88788..88973)
                     /locus_tag="ACF3UO_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656140.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(89823..90164)
                     /locus_tag="ACF3UO_000078"
     CDS             complement(89823..90164)
                     /locus_tag="ACF3UO_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFD3656141.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVIRPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(90164..90394)
                     /locus_tag="ACF3UO_000079"
     CDS             complement(90164..90394)
                     /locus_tag="ACF3UO_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3656142.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            90690..91028
                     /locus_tag="ACF3UO_000080"
     CDS             90690..91028
                     /locus_tag="ACF3UO_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656143.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPIQIET
                     LVQRISTREDFAIVECEIVAIFVEEGILHDPTHINVDKWQPLIYKLREYTTANQSLSL
                     NFRFQEFKES"
     gene            complement(91233..91808)
                     /locus_tag="ACF3UO_000081"
     CDS             complement(91233..91808)
                     /locus_tag="ACF3UO_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006974 - DNA damage response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HFD3656144.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPEQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDVSFARKIITQQMPELVMEKV"
     gene            complement(92173..92754)
                     /locus_tag="ACF3UO_000082"
     CDS             complement(92173..92754)
                     /locus_tag="ACF3UO_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3656145.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASETGKGQFYYYFS
                     SKKEVCLAVIHAHMVVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWIKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(92937..93563)
                     /locus_tag="ACF3UO_000083"
     CDS             complement(92937..93563)
                     /locus_tag="ACF3UO_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFD3656146.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFSLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(93585..94913)
                     /locus_tag="ACF3UO_000084"
     CDS             complement(93585..94913)
                     /locus_tag="ACF3UO_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFD3656147.1"
                     /translation="MEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTCI
                     NIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARFL
                     SNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPEK
                     LVIIGAGYIGLEFASMFNEYGSKVVVLDAHPEFLPREDEDIAQMILEDMTNAGIEFHL
                     GVSVDQVADQESTAAVTFTENGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDRG
                     AIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVPY
                     SVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETDL
                     ILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(95072..95473)
                     /locus_tag="ACF3UO_000085"
     CDS             complement(95072..95473)
                     /locus_tag="ACF3UO_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3656148.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(95559..95765)
                     /locus_tag="ACF3UO_000086"
     CDS             complement(95559..95765)
                     /locus_tag="ACF3UO_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656149.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(95860..97362)
                     /locus_tag="ACF3UO_000087"
     CDS             complement(95860..97362)
                     /locus_tag="ACF3UO_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFD3656150.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(97380..97835)
                     /gene="argR"
                     /locus_tag="ACF3UO_000088"
     CDS             complement(97380..97835)
                     /gene="argR"
                     /locus_tag="ACF3UO_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3656151.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(97933..98550)
                     /locus_tag="ACF3UO_000089"
     CDS             complement(97933..98550)
                     /locus_tag="ACF3UO_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3656152.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            98771..100144
                     /locus_tag="ACF3UO_000090"
     CDS             98771..100144
                     /locus_tag="ACF3UO_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3656153.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            100219..101331
                     /locus_tag="ACF3UO_000091"
     CDS             100219..101331
                     /locus_tag="ACF3UO_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3656154.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(101403..103040)
                     /locus_tag="ACF3UO_000092"
     CDS             complement(101403..103040)
                     /locus_tag="ACF3UO_000092"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFD3656155.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(103208..103816)
                     /locus_tag="ACF3UO_000093"
     CDS             complement(103208..103816)
                     /locus_tag="ACF3UO_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3656156.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(104200..105351)
                     /gene="queG"
                     /locus_tag="ACF3UO_000094"
     CDS             complement(104200..105351)
                     /gene="queG"
                     /locus_tag="ACF3UO_000094"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFD3656157.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(105370..106122)
                     /locus_tag="ACF3UO_000095"
     CDS             complement(105370..106122)
                     /locus_tag="ACF3UO_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656158.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(106263..107213)
                     /locus_tag="ACF3UO_000096"
     CDS             complement(106263..107213)
                     /locus_tag="ACF3UO_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFD3656159.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(107214..108053)
                     /locus_tag="ACF3UO_000097"
     CDS             complement(107214..108053)
                     /locus_tag="ACF3UO_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3656160.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(108050..108796)
                     /locus_tag="ACF3UO_000098"
     CDS             complement(108050..108796)
                     /locus_tag="ACF3UO_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3656161.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            109034..110404
                     /locus_tag="ACF3UO_000099"
     CDS             109034..110404
                     /locus_tag="ACF3UO_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3656162.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(110459..111355)
                     /locus_tag="ACF3UO_000100"
     CDS             complement(110459..111355)
                     /locus_tag="ACF3UO_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3656163.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(111469..111639)
                     /locus_tag="ACF3UO_000101"
     CDS             complement(111469..111639)
                     /locus_tag="ACF3UO_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656164.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(111636..112313)
                     /locus_tag="ACF3UO_000102"
     CDS             complement(111636..112313)
                     /locus_tag="ACF3UO_000102"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3656165.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(112404..113309)
                     /locus_tag="ACF3UO_000103"
     CDS             complement(112404..113309)
                     /locus_tag="ACF3UO_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFD3656166.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            113484..114938
                     /locus_tag="ACF3UO_000104"
     CDS             113484..114938
                     /locus_tag="ACF3UO_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFD3656167.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            114954..115985
                     /locus_tag="ACF3UO_000105"
     CDS             114954..115985
                     /locus_tag="ACF3UO_000105"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3656168.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            115992..117179
                     /locus_tag="ACF3UO_000106"
     CDS             115992..117179
                     /locus_tag="ACF3UO_000106"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFD3656169.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            118129..119991
                     /gene="ltrA"
                     /locus_tag="ACF3UO_000107"
     CDS             118129..119991
                     /gene="ltrA"
                     /locus_tag="ACF3UO_000107"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3656170.1"
                     /translation="MENVSASHSIRHMEYYGLIDSFDSLYKESSENKIFSNLMEIVTS
                     PNNILLAFRNVKGNSGSTSPGVDKKNIDDLKAIPNIEFIKTVQTKFSEYKPQPVKRVD
                     IPKPNGKTRPLGIPTIWDRIIQQCLLQVLEPIMEAKFHDKNYGFRPNRSAHHAFAQAV
                     RMAQLSKLTFVVDIDIEGFFDNVNHSKLIKQFWTLGVRDKWLLGVIRAMLKAPIIHRD
                     GRIEHPKKGTPQGGVLSPLLANVVLNELDWWISSQWETHPTRKNYDCYHQTRKQWIKS
                     NKYRALRASKLKEIYIVRYADDFKIFCRKRSDADKIFLATKLWLKDRLKLDISAEKSK
                     VVNLKKQKSDFLGFTMKLVRKRKSFVIETHMCAKAMSAASNKLAKQIKVIQHSPTQVE
                     LQKQLSIYNSMVVGIHQYYKKATHISVDCPRINQRLMIIIKNRLDIKRKGPPPSDFIK
                     KNYARSKQLRWLNGVPMLPFGFIKHSHTSLPKIGTCKYTPEGRVLIHRYLTFPIDIIN
                     QLMNMSNPNESIEFRDNRVSKYSSQVGRCRVTKEVLELADIYCHRIVPKNLGGKDNYQ
                     NLVIVHRNIHSLIHEEDKTRASLLIQNMRVTSAQLEIINQFRKKAKNRELSLNL"
     gene            120105..121403
                     /locus_tag="ACF3UO_000108"
                     /pseudo
     CDS             120105..121403
                     /locus_tag="ACF3UO_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
     gene            121375..121761
                     /locus_tag="ACF3UO_000109"
     CDS             121375..121761
                     /locus_tag="ACF3UO_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656171.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(121961..122629)
                     /locus_tag="ACF3UO_000110"
     CDS             complement(121961..122629)
                     /locus_tag="ACF3UO_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFD3656172.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(122818..123615)
                     /locus_tag="ACF3UO_000111"
                     /pseudo
     CDS             complement(122818..123615)
                     /locus_tag="ACF3UO_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(123896..125275)
                     /locus_tag="ACF3UO_000112"
     CDS             complement(123896..125275)
                     /locus_tag="ACF3UO_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3656173.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSVSDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(125451..126620)
                     /locus_tag="ACF3UO_000113"
     CDS             complement(125451..126620)
                     /locus_tag="ACF3UO_000113"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3656174.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPKHVKQAGIAAIEEDFSHYTGMRGLEELREAACMFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(126595..127746)
                     /locus_tag="ACF3UO_000114"
     CDS             complement(126595..127746)
                     /locus_tag="ACF3UO_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3656175.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSGAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFHYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSRSKEERVYNDEFIQSI"
     gene            complement(127706..129067)
                     /locus_tag="ACF3UO_000115"
     CDS             complement(127706..129067)
                     /locus_tag="ACF3UO_000115"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFD3656176.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYSKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(129064..130065)
                     /locus_tag="ACF3UO_000116"
     CDS             complement(129064..130065)
                     /locus_tag="ACF3UO_000116"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFD3656177.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(130081..130776)
                     /gene="dapD"
                     /locus_tag="ACF3UO_000117"
     CDS             complement(130081..130776)
                     /gene="dapD"
                     /locus_tag="ACF3UO_000117"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFD3656178.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAGTVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(130782..131498)
                     /gene="dapB"
                     /locus_tag="ACF3UO_000118"
     CDS             complement(130782..131498)
                     /gene="dapB"
                     /locus_tag="ACF3UO_000118"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFD3656179.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(131495..132376)
                     /gene="dapA"
                     /locus_tag="ACF3UO_000119"
     CDS             complement(131495..132376)
                     /gene="dapA"
                     /locus_tag="ACF3UO_000119"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFD3656180.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(132379..133179)
                     /gene="dapF"
                     /locus_tag="ACF3UO_000120"
     CDS             complement(132379..133179)
                     /gene="dapF"
                     /locus_tag="ACF3UO_000120"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFD3656181.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDTDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(133166..134425)
                     /gene="lysA"
                     /locus_tag="ACF3UO_000121"
     CDS             complement(133166..134425)
                     /gene="lysA"
                     /locus_tag="ACF3UO_000121"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFD3656182.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKERSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(134640..134810)
                     /locus_tag="ACF3UO_000122"
     CDS             complement(134640..134810)
                     /locus_tag="ACF3UO_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656183.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEREETALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(134911..135474)
                     /gene="efp"
                     /locus_tag="ACF3UO_000123"
     CDS             complement(134911..135474)
                     /gene="efp"
                     /locus_tag="ACF3UO_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFD3656184.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            135902..136819
                     /locus_tag="ACF3UO_000124"
     CDS             135902..136819
                     /locus_tag="ACF3UO_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFD3656185.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            136832..137977
                     /locus_tag="ACF3UO_000125"
     CDS             136832..137977
                     /locus_tag="ACF3UO_000125"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFD3656186.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPHHELHGVAKQQMSGFSGMISFTLKNEETAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            138148..138606
                     /locus_tag="ACF3UO_000126"
     CDS             138148..138606
                     /locus_tag="ACF3UO_000126"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFD3656187.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
BASE COUNT        39944 a        28937 c        24313 g        45540 t
ORIGIN      
        1 gtctcgtcct gtatcctcgg gaaattttat atattgaaag tatcaaaggt ttgaaaaacc
       61 aagttatggt caaaacaact acagaagata aattagtgaa tacttcttta aaacaattga
      121 agacagagtt agaaaagtat gcttactttt tacttttaaa atcttactgt atcaacttat
      181 cgcaattgca gaaaattgat tctgctcatt atgtgttaga atttttcaac ggtgactcct
      241 tactcgttgg tcgaaagatc tttgaaaaga caaaggaacg tttccatgac ttccaaaaaa
      301 ctgcttcgag ttgatgaata agagctgaga cgtaagcata gcagatttca gggagtgggc
      361 cttgaatcgg ctccactccc tgaagtcgtt gatatgattt tacgcttcct cttctgtagg
      421 agcatctgtt aacgaccatg tgaatgttga aacgtagttg tctacagcat aattggatac
      481 aggaacaaat aattccactg attgtctccc ttgttccaca ttctctccta atgaataaat
      541 ccatgtgcca atcccttcat ttgctcctgc agttactaga tctactgcct gatctgctgg
      601 gatttcgatt ccttcagcgc cagttccaga aacggtagat ggcattccac tgctattagt
      661 tgcgctattt cgaatcacgg cgtttttgaa tttcaccttt gaaccagtta gtttattcgt
      721 atcagatgtt gtaccaataa attctgttcg tttgactgat aatttccaac cggcataatt
      781 tccgctttta tccgttactt gtacgaaatt ctgtacttgt gtttgtgctc cagtactgtc
      841 cgttccgctt tgtaatgcag catatactgt ttttgctgta cctaacttga ttgttccaaa
      901 atcaagatct ggagcttggt caatcgtcag taatccggat gttccctgat ttggttcgtc
      961 aggtgtaaaa ggagtatcag gatcatttgg atcaacagga ggaactggaa caacgtcttc
     1021 aggatttgca gcatctggtt tggtcacaga aatcgttcct tctgtagtgg ctgagctctt
     1081 attctcagca aaaacacttt gtgtacataa taatagactt ccagctagaa cggtacttaa
     1141 tgcaattgtt tttttcattt ctttttcctt ctttctttta aaataaataa tccagcaaat
     1201 aagccaataa gaatgactcc aacaagtatc agccatcgcc agtcaaatgt ttctggctga
     1261 ttttttaaat caatatcctt ttcattcaat tggtccgctg catcatcagt tatttcaaaa
     1321 tcggtatgga gattccagcg tttttctttc caagcaccct tcacaaccgc ttgataatgt
     1381 cccggagcta atttttttcc ttctaatggg acaagtaaat caaaatttgt attgggtgct
     1441 acatctattt tttctttttt tattgaaagg taaggctctt ttgtttcttt tttgtagatt
     1501 tcaaccgatg tagtcaagcc gaacatataa gaagcatttg gattttgaag attcgcctta
     1561 atcacatttc ttccatcgct ttgatccgca taagcttttt ttaatttcaa atctggggaa
     1621 gactcttttt cgctatttca aatcaagatt gctttcactt gagaaaactg attgacgaca
     1681 ccaactgtac ttttgttaga aacgttctct tttttttctt gaaacgtgat ccctcctgcg
     1741 accacaccag ccagctcttt ttctggcgct ttcagtgaaa gtgtctcagt gaccgcactt
     1801 tgaggaggaa cagttatttc tcccactgtt tttgctaagt ttttcatatc ataacttaat
     1861 gtttcatcaa atttactttt tgattctcca tattcgatca caccgtttga attcgtcgta
     1921 gcggagtgga tcaatgtctc aactgttact gatttatctg ttcggttaaa gaccgtgtag
     1981 gggatttcct gtgttttccc aggctccatc cttacattta tatatgtttt gttcttatca
     2041 atctgattag ccggtaattc aaaatctacc gcaaaattga attcggaggc atggacaggt
     2101 gtctgccaaa ggatgaatcc aaggagaagg atcataagta aagagcagtt gtttcgatga
     2161 cttttattcc atattcgatt catcaatcat cctccttgat ctttattctg tcggcgcatc
     2221 tgctaatgtc catgttatct ctgctgagta attaccagct atctgatttt ctttggttaa
     2281 gacaagttta aacgcccgac cgttatttaa atattctgaa taatctgctt gcacattcgt
     2341 tgaattttgt cctctgacaa tttccagttc ttcttcattc actaattgat actcctctcc
     2401 tttcttgaaa tataggacat cctgcataga aaatcctgca tcatttgtga aaggctgaga
     2461 taattttatc gttaagatcc acggattttt cgtttctcgc tgatcataaa tccataattt
     2521 ttcctgtata tccatttggc caaatgcttc ttgtgtcaaa ccagttgctt tgatctgacc
     2581 aaaatcgagt ttggaagggg caagaaatga gagaccacct tctactacga tcttcgtagc
     2641 aggtgcaaaa ggcggggcat catgataaac aactggcgta tcacttggat tgtgattccc
     2701 aatttcatcg ttggtacttg gcttgttctg cacaccctta gcagtagctt ctcctgcttg
     2761 gtcgtttaat acaatttcta atacatctcc tgcaaaaagt tgattttctg ggatagaaag
     2821 aacaaattcc cctgtatcat caatagttgt ttctgacaaa acagcttgat tttttttcaa
     2881 tgaaaccaag gctcctgctt cacctgtacc tgtgatcgtg cgagaagctg cattgatcaa
     2941 tgtggtactt aaattagcag gttcaggagg aatcacatcg actgtcgttt tggcagagtc
     3001 cagttctgtc acttcttggc cacctcttac ttttttagca gcaacaactt gcacttgatc
     3061 ctccgttttt aatctctcat cattgggtac ttgaacttcg aacaagccgc cttgttcgcc
     3121 ttctccccat gggttatatc ctgccccttc attttcatct gtttgtcctt gcgtgagagc
     3181 agtaatttct acagatgatt tcgtcgtatc tgcgtaagta atacgtaaag tcacttctac
     3241 ttcgcctgtc caagcatctc ttggctttgc ctcgacacct tcgggaacaa cgacatgccc
     3301 atagattttt ttatctgcat tcgttggcac tcttaaggat tcaatcatcg ggagctgatt
     3361 attggcactg attcgattat aatttttcat tccggcacct gtctgagcaa attcatttgt
     3421 taaacctgca ctagggcttg atacgaaatt gcctaagtcg gtcccattga tcgataagtc
     3481 tgtcatatca gaaaaataat ccgggtcttt ttcaaagtta tcgaatgttg cgcctgtttt
     3541 tcgccataaa gcgatttctg aatgggcgat ctttaaagaa gaatctccat ttccttggaa
     3601 tacccagccg cctatgccat tggtctcgct tccaatccgt ttgttttgga aatcaaaata
     3661 ggtaggagat tctaagtcca cattcaacac atccccactg atgatgccgg tcttatcttc
     3721 ccctgttttc ccgaccatga ctaaataagt tttttcacct gccgtaaaat ttaaatcaat
     3781 atctccagtt gtatctacag ttgctccgga atctgcgcgt atatcgatat ttgatttttc
     3841 tccagtgact gtaaaatcag ctgaacctgg actttctaga aaaccagaag cgtcataaaa
     3901 ttggatcgct tgatttcctt gattgagtct gttcacgtaa gatttgccat cacctgtatt
     3961 tcttaccctc aatgagcctc cattggttac tgtcagcttt tgcgtaccat tctcaaaacg
     4021 aactgcgctg gaacgcccac tctgcttatc gatgtcgata actgatccgg ctccttctac
     4081 gatcaaagaa aggccttttc ctacaaaacg catcccattg ttcccgggtt gatcgtcatc
     4141 tccagccatt ttgaccgaga tttgtccacc acttgataca tggatttgac tagaatctcc
     4201 ttgcaagcga aatccgcccg tagttgctgt attgatggtg attttcccac cattcgatac
     4261 agtgactttc gatcctgaac ctctcatttg gatgattccg cgattgttgt cattggtaat
     4321 attgatcttt gtatttaccg aaaattcgct tcccgaacca ctgacttcaa acatgacatt
     4381 accaggtagc gtatcgactg cctctccttc atcgctaacg ccatctgccc gatcataatc
     4441 aagagagacc tttgaaccgc ttaagatatg gattcctggc gctgtttttc cactaccagt
     4501 ctcatctcct gaatctagaa aaccgtagaa tttccctaga tacggtccat aaagttgact
     4561 accattgatc acattcaatt gatagcttct acaaaaatag gctttacccg gagcggcatt
     4621 cagtccttcc ttcactggtt ggacatccaa cacaccggaa acaccatcta atgtgacagt
     4681 tgcacgagga gcgtaaatca gtcctaattt ggacccatca tacaaatcaa gtgtcccggt
     4741 aaattttatt tctcccgtaa aatgatatct gcttccccaa aaatcggtca tataagcaat
     4801 gataatggca tttccatcga tatttggtgt caatccacct ggatgtgcag ctgttccttt
     4861 aaaattctgg aactcgatcg actgaggtat ctcattgata taaatatggt gtgtgccgaa
     4921 attgtgagcg aatccaccaa aatcaataac gatatctcgt ttgatctcta attccctgtc
     4981 taaagtcaaa ggctgaatca gtcggatctt agttactgat tcgtctgcga gaagctgcgc
     5041 cagttcttct gttgtggcag cttcgctgta cccatccgct gaaacagctc ttgccagtgc
     5101 cgcttcactg ctatcagacg tttgttcagc tacttctgag gtctcacttg tcttattttc
     5161 ttcttgcctt ttattagtag aagcctcact ttgagattct gtagtttcag aagtaatcga
     5221 ttcttctgaa aaagtagtct tgtcaaaact ttgattctct gattgcgttg attcgtttgt
     5281 tttctctaca tcggcaaaaa cggatgtcac catcaagaga gggaagacaa acaaaatcga
     5341 cgcaatcagc ttttttacac attgattcat tctccaccat cctctctgac gttttgacaa
     5401 ttttatttta tcgttttaat ctatttccaa ttgtactttc atatttaaaa tatgtatttt
     5461 tatggaaaaa tttttctatt aggtgtaaat ttcttttttg tacaaaaaaa aggctgtgac
     5521 aaaagtcttg tcacagtccc ttatcccgaa caagcggtgt tctcccgcca actcctcggt
     5581 cacaacctcc attttaacaa taaacctgta aatgtgaggg caatactttg attgtcacag
     5641 gtaatttatc cccttcatct ccatcaacat tcgtcgtcaa ttcttcctca tcagctaatg
     5701 acacaactaa ttgctcacaa gtaaggtagg ctagattttt cgtagattca tctactcctt
     5761 ttaataggtc tggcaatgtt ttaagcgtat cgatcaaaga agaatctttt aaataaacca
     5821 aatggagctt accatcatcc acttttgcat ttggaagtaa tgtttcaaaa ccgccgactg
     5881 agttagttag tcctatcagc aaggtactgc tctcaatttc ttccttcttt ccatcaactt
     5941 ctacgtgaaa cgagtaggat tgtgtggaag ctaactgttt gattcctgac atgaaataag
     6001 ctagttttcc aaatttcgtc ttcttctccg catctacatc attgattgat tcagggatag
     6061 agccaattgc gacgacattc ataaaatagt cgtcatttat ttttccaata tccaatggct
     6121 tgactgattc aatcgaaaaa tgattgatcg cttcctcagg ttctagcggt atccctaatg
     6181 ctcgagccaa gtcattcacc gtacccaatg ggaaaaatcc gaaatttggc cgatgttctt
     6241 gttcagcgat tccactgatt ccttcgttga ctgttccatc tccgcccatg acaaacacac
     6301 tatgataccc ttccgtagcc gcttcgcgag taaagttttt tgcatcccct gctttttttg
     6361 tatgcaagac gaccacttca tcaaacaccg attccaattt tgctatcgct aattgctcaa
     6421 attcctttgc ttgttcaccg cctgaactgg ggtttaccac taataaaact tttttcatca
     6481 ctttctttcc cttctgattg atttctttaa tataacgata gcataaagaa aaaaattagg
     6541 ctgtgatgaa gtactgttca tgaaacattc atttattttt tgacaagata aaacatccat
     6601 actatgaaac tgaggaaaat taaaacaatg atataggaaa taaaagaaaa tgataggcat
     6661 tgtataccta ataaagtaaa aatcttaggt ggcagataaa aacacaaaaa tagcaagaga
     6721 atgtaatagc gtttcttcca ctttttgtta tcagacctta tagcgatcag aggaatacca
     6781 aatgcataac tgaaaaactc ttgatgtact gttaatatgt cacggccttg aataataaat
     6841 gcgacaatcc ccgctataat tagtgtgcct aacaccaaaa cggaaaattg atgaatatat
     6901 tttatataca aatgatccat tgtacttcct gcctttttat ttgtgagaaa aacaaatccg
     6961 tatacgtgaa taacttctag aaataaaaga aatttgcaaa accactccat ttatctactt
     7021 ctacgtgcat tttttgatat tgttttcttt atttaagatt atacagaaaa atatctaggg
     7081 tcgctggatt ctaagtaaaa aaaattttta aaataaaaag aactaaatca agtagtaatt
     7141 aaactactgt tgatttagtt ctaataaaaa gatttagatg aacagtttta ttgatttaaa
     7201 tagttcatat tttttattta taccgcttat ttactacttg ctgtactaga atctgaagtg
     7261 aatgtactca aaacattttc aaagtctttg tctttgattt ttacattagc gtctttcaat
     7321 acttcgccaa ttactttatt ctggaaggta ctgtcactta attttgtgtc tgttgcaatt
     7381 tctttcaatt cttttttgta tttatccatg tcgttgcctt tgttttggtt tttcaccatt
     7441 ttaaccacat aatattccgt agtataagtt gaagcattgg tagaagtgat cacatcagaa
     7501 acttgaccat ctttcaactt aaaggctgct tctttgactt ctgccggaac cgttgtagta
     7561 gtggaatcaa atttcacttt tccgccatct tcttttgtcg tagtatcagt tgacttgtct
     7621 ttggctaatt tagagaaatc gtctccctta tcagcagctt tcttcacatc ttttgcatca
     7681 tcttcacttg ctacttggat aatttgagct tccacttctg gatggaaaga ttcccaagcc
     7741 gtttttaaat cttcatcggt caatttgata tgtttcttta gaccttcttg aaaggctaga
     7801 ctttgtttga tactgtcttt gaatgtttgt tctgtgtaac ctgcagattt caattgtgaa
     7861 tcaaatgaat cacccaattg tttctttgtt tgatcatatt gagaatcgat ttctttggtt
     7921 gatacgtcat ctccatattt atcttcaaat acttgataaa cgatcaactg ttgcacagcg
     7981 gaatctgctc cttgcatttt tttcaagcta tccattactt cttgttcgct gattgtaccg
     8041 cctttataac taacggctgt tttttcaccg gcattcgtac agcctgacaa taagccagtg
     8101 cctagtacga tggcaagtgc taaaaatctt tttttcattt atcaattctc ctacttttcg
     8161 ttttttgcga attgctaaaa acaaaggtgt tcaagatgaa aatcatcaag aacaccttta
     8221 ctaatctgct cgatacgtcc tgaatagata taaggctaca caatccagaa agttcgctca
     8281 gcagaataaa tgtcaagtag cacatcacac cttaatatac tacttctttt gttaccgttt
     8341 ttcaagtcta tcttgcgttc cgtatttaac gtaactaatt cttagaacaa atgttatcga
     8401 ttttgttttt cttcttccgc tgctgggata ttcaaatcag acacttttat gttcgatttt
     8461 ccagacattt ttttgttgtt tttattatga tatattttta tacaactaaa aatgaatata
     8521 ttaaaactac caaaaataac ttttaacgct gtttcattat atgttttttc tattttatat
     8581 aaacttttgg atacttaata ccaaccggtt ggattgtacc aacatgagaa tgtgtcagtt
     8641 ctatttcctg tcgcacttgc ataggcccat actccttttg ttgcatttgc tgatcgaata
     8701 gagtttccaa ctttcgcttt tgcaccgtga cgattataga cacgactata gtggttagaa
     8761 tgacctgttt ttctcgtaca agttgtatca ctataataaa cccatcttcc agagctatga
     8821 ttaattgctg ttctagaaat ttcccggtct actggtaaat ttgacttaat aatattacct
     8881 ttagcatcaa aatgaatctc tcctggcttt aaagatttgt aatagatttc accgtgaact
     8941 gaatttgctt ccacttcaga tgacatagcg tttcctccaa caaaacctat ccctagtgca
     9001 caaataataa ctgctttttt cataaaacga catcctttcc tttttgattt ttaaagcatg
     9061 atcttcttgt ttcctatttt ggtcagatat ggatcatgcg tgactacgat aactaacgta
     9121 ccttgggaag cttgttgcga taagatttca actactttat ccttatttct tttatccaat
     9181 gacccagtcg gttcatcggc taaaatgatt ttgctattct tcaataagac tctcgcacag
     9241 gcgattcttt gcttctcacc accagataat gtgtagatag gcgtacttag cttcttgttt
     9301 atatttactt ttttcaatgc ctcatacttt gctgttcgct tatctgaaac atttaaattc
     9361 gaaaacttca atccaatatc taaattaaaa tcgattgttt catattcaat caacccaaaa
     9421 tcttgaaaaa gaaaagatat ggtatttctt tttatcaagc gcttctctct cccagttaat
     9481 tgtttcgtct cttgatcgaa caaatagaat tgtcctgaac tgaactgatc attcaatcct
     9541 aatatattca ataacgtact tttacctgct ccactttctc caacaacagt cacaagatcc
     9601 ccagcatccg cagtgaaacg atccaaatga agaatcgttt tgtttcgaat gatttttttc
     9661 gcacctttta tcactatcaa cggctccaat tgttaacctc cattcatcag caataactga
     9721 cttttctttt ctgtagacaa aataaaaaca actgaaagaa taaaatcaat gaagctaaag
     9781 aaaaaaatat taaaaagata tttaggctct ctttctataa gaaaaaggaa gattacactt
     9841 gtcgttcccc atttgatgag gttcatcatg aagaaatctt tatacgtttc aaagagcgaa
     9901 taaccacttg aacgaaagat agcgattttc cgacaattgt agacaaaata tatgcataac
     9961 atgacatagc tcaacaagaa gaaagaaaag aaagtgagta aaaatatctg tatcaagtaa
    10021 tgaaatgatc tgcttaacac tttgacagct atctcttcag tctgagtata cggaaatgat
    10081 aactgcaagt tatcacgtaa ctgactttct tcaatcagct caaataacct ttctttcgac
    10141 aaagagccta tcttgatctt taacggtgga tagatttctc cgctgagaat atttctttcc
    10201 aaatacatac tgtttttcaa tgtcagtatt tcaacaaccg gataatgttc gatccagggg
    10261 atagaaggaa taaatgtata aatgggttga ttgtttttta taaatagaaa tttcggttct
    10321 ttttcactga tttcttgata atattctgtt atttgcgcca ggtcattttt taaatctgta
    10381 tgtctatatc gttcagggat caatataaca gggtgcgttt ctttttcggt tatttggatc
    10441 aaccttccag agacatcaat caaaggaaat ttcttaagat aattcagatt tatttttatc
    10501 cctctgccaa actgttcatt ttcttcattc aagtaatctg atacattgac taatatactt
    10561 ccgtttttat tcaaagtttc atataattcc tgatctgctg ctgatgcaaa acgattggaa
    10621 taaataaaat ccacgtggtt tttcccgatg gttactggat aaaatacatg atagtcctca
    10681 ccagcgattt cttttggtgg ttcatgggaa acagctaact gtgaagaaga aaaaacgata
    10741 gttgctaatt cgacattggc aacggtcaaa agaagagaaa acaacaatcc aaatgtaaaa
    10801 agaatgtatt ggatatagtt gaacgcttct cttaacgaag cgattttttc aactaataaa
    10861 agagaaatca aagagatacc atatattccg ctgaacaaga aaacgtacat ctggaacaaa
    10921 taaagaaatt gctccttata atacataaaa ataaaaccac caatgattcc tgcaattatg
    10981 aatgtaataa tgattttctt tttccccaat aaacaccaca atacttgatg taatgaaaag
    11041 tcattattca acaataaact gatttcttta ttcatcaata agaaaaagga tgataacaaa
    11101 aggaataaaa gaatcaatcc aatagttaaa tacactcgat aattatatac gtctgtattt
    11161 gaaataaccg aatacgaata gctattttca aagtcttcaa aaatattagt ggcataatca
    11221 gtgtgaaatg cttgattgaa tcgatcagtg aatagtgaaa tgacccgttc ataggcttct
    11281 ttttctctcg tcatcaagaa aaattcacct tcaaaatctt ttattttgat cgattcttca
    11341 atggacgtta cgcgaaagga ggtattagaa tagggtacct tctcgtgaga agatttgaca
    11401 tccccttgat aatacaatgt catttcaagc tttggctgta tcttgaagtt ccaagatgta
    11461 tctacttcat tggattcatt tactgttttt ttcatataag aaagctcagt ttctgatgag
    11521 acattttcaa ataccatgat tagctgctca tattcttctt gcccaataaa atgttgtggc
    11581 aatcgaatcg gagtataagt atctgtttga tggaaaaatt catttgtccg atagagtacc
    11641 tgtttattta tactaaccaa ggcaaaacca ctcatgatac cggtcactat gattgtgagt
    11701 aaaactgtga actttttttt gattatcacc actctccctt acttaaatga ttctttgata
    11761 aaatcatacc gtttttcatc aaaaaaacgt atctatcaag tgtataggtc atgtagaata
    11821 aatctatata ctgtagaatc gaaaggagaa gaagatgaac accggagaaa aaatacgaac
    11881 ttaccgcaga aattgtaagc ttacgcaaaa agaattaggc gaaaaaattg gtgtttccga
    11941 taaaacgatt tctagttggg aaaattctcg tacaatgcca gactttgaaa tgctgtcact
    12001 tttacatcat actttaggtc tgccgattga ttttccttct attgaatcag ctaccgaatc
    12061 aatagaacca acattgccag atgaacctct tgttaacaag aaatcttatt catcaaaaca
    12121 acccttctca ctcaaaaaga cactatcttt ctttctgctc gtcttttgtt tggtctatct
    12181 ttttcttatc aattatcaat acaaaaatga aacgatcgat cgattcaatc cttttttgaa
    12241 accacaaatc ggctatacca cactccctgt aggatacgtg gacaattcca tcgaacgttg
    12301 ggtatgtaat gatatctttg gccatggtac atggctgtct tttcacgctg gagaggtaga
    12361 aaaagagaaa aaccatgctg taatcaaaca caaaggaaaa cacgtcatga acgttcgcct
    12421 gctcacttgg gaagccattc cctcagatta ccaagaaatc ctcagccaag actatgacga
    12481 cgccttaaaa agaagccctc aggagccaga taggcattaa gtaggagatg aacgtagaga
    12541 tagaaaaaat caatgcacat gatcttatcc aaaaaacagg ggtacaaatt aattgaaaaa
    12601 gccttgagat gaaagttcct aaataaaaaa gttcagaatg ataggtattt ctggcttata
    12661 gtataatatt tacgccacag cctcccaatg attctttttg gaatcataat caaggatgga
    12721 cattcacaaa aatattttgc tcattcgatc cgaatagatt aacgaccaat ctagtaagta
    12781 atatagattg gtacgtagtc aagctgcaca taatttagat caattttagt tcttttttat
    12841 atttctatga tctgctcatt tacttttata tgatggctta cagtaacata aataaatatg
    12901 ataatcgctg gtagtttatc caagagtact caataaaata caaaatggat tgttcaagcg
    12961 cctatcataa tgataaaatg aaacaaataa acgatacaag gaggaagaga ctttgagtaa
    13021 tggcagaaca attttttcat tgtaaaaatt gttcagttgt taatctatgg gatttcggta
    13081 gcatgggcat ttttttatag aggaatcaca ccaacctggc cgttttatct cttgttagtg
    13141 ggaatattag taggaaattt tgcccctctt cactatcgta cgaacttttt tccaactgat
    13201 tctggccttt ttcttaaaac aaagacgcga aaattagaaa acattattga aatgacaatt
    13261 acctgtataa tcattttctt agttatattc ctaaacgtct tctaataaga atctcttaaa
    13321 attagcttgt tacagttagt tacctagttt atataacaca gttatcttat cttccttatc
    13381 aacatctttt gccaactctt tgtcttaaat tcgaaacata taagcagagc tacgaacacc
    13441 aagactgttt cggctctgtt ttttgcatca aattcactct tatatagctg ataatctcgg
    13501 ctctttaaaa gaaattattt tcgcttcatt ttattataaa aaggctagga accttgatgt
    13561 tatcaggttc ctagccttta tttaagtatt accccacaga cccttccata tagatttttg
    13621 aattacacac tagtttaaac taaaacaaac aaggaaaaac ttaccattta atcataaaat
    13681 tagctcatat gaatatatta gaatgtaaaa tagactggtc aaaatctggt caaaaaagag
    13741 gactaataca ggtagtcctc ttttttgtta ttttgatatt ctaaatcatt ttttattgga
    13801 ttattccctt gttcgatgta gactcaaatc aatctcttta cttgctaaca tcctttattt
    13861 taccttgacc tgttgataat agacagttaa atcttgattt aaagtggggc aattaatcaa
    13921 gaaaacaggg ttctaagcct catttgttag cttgttctct tagtaatatt cctcgtgaag
    13981 aatcgggacg attgtttggt caataaacaa tatctcactt gcatcgaaag aatatttctt
    14041 gaacaactgc atatcaactt cttcaatacc tacattccag ttaatgtctg aacctgaggt
    14101 aaaatcttgt actggtatga acatgaactt atctttggat aggtgaatag atgtcactgc
    14161 ttgaagtaat aaaaatctgt aaaaacgtgt tcgtaaatac ttcagataat taattgcttc
    14221 ggtttcggta tcagcagaaa atagcactag gtatgaatct gtaactactt cattaggttt
    14281 aataactctg ttagtagaaa tcaccttaaa cataccattt ttgttcggtt cacctgcatg
    14341 ttcgctagtc agtgagctac taatgacttt atactttcca accatatcct gtcctttagt
    14401 gatatcttcc agtggaacaa agcctacccc accactagag attactttta ttgaatttct
    14461 ggaatcctgc acttcttccc ctcgaatttt cgttggaagc ccaaatgggt tacgtgatat
    14521 aacaaagtca ccaacactag cgtgttcccc aattttgtga attgcagaaa tggcttcatt
    14581 atatcgcaca aacactggaa actcgttcat ttttcgctct tgtgtatttg atacaccatc
    14641 atgttgatta gtatactgtg tcaatccatt atatttctta tcccacaaga aatagctaac
    14701 accgccacca atactggtgt ttgggaatat ttctttccca tttactatat ccaccatcac
    14761 cttcaagcta gagctgttaa gcataaagtc acggtactta tctaaccctt taccacctgc
    14821 aaaccacttc gaaggagtaa tcatcgaaac atagcgttct gataacttaa cagaggtttc
    14881 tacaaataga ttatatagcg gtgtagcact agctcctgaa cctccatctt tctcctgata
    14941 aggtgggtta ccaattatca catcaaattt cacgttttta taaactcctt tcaaattcgt
    15001 taaaccgtca ttgattgaac gtttcatact cgtaactaat tcacttgagt attcaacatt
    15061 taccttccat gcgttataac caatcaaagt cctcttcgtt atcgtcttag ccattggagt
    15121 tttagaaatg acaaaaattt gctctgataa tactttttcc catattgcct ctgaatctac
    15181 ccttccagca ttaatatcgc tttgtttaag gagctgaaca tagtacatac tcgttgctgc
    15241 atataaagga tatagccctg tttttgagtt tatctcaaga atctttctat tttccttaaa
    15301 aatatcatct gtacagtcag ttttcctcca tcgcacgatt ggttgaccgt tctccgtaga
    15361 attttggtat tcttcatcaa agaaggaaag tccaccgata gtgttaccaa ggtgcatatt
    15421 aacaactcgc catggagtca atacggtttc cttgtctgga tttttaaaag tgctaaataa
    15481 ttcacctatt ttcctagtac gttcaataac atctaactca tcataagact ttgcacgtct
    15541 acggattatg cgtcctgcct ccacaaaaac gtctgcatca tagtactcaa taaactctct
    15601 gaatcgccct ttacttaacc cctctggcat gaactcattc catgaagcct catcaaccaa
    15661 attaagaaac atctcaatag taacgtcatc tttaatatca atgtccatcc cataaatcat
    15721 cataggtatg cgaatagaaa cgcccctcaa aatggaaatc attttatttc gctgctctcg
    15781 aagcctcttt gccctatcta ttgcttcctg ttcctctttg gtacgttgac gttttggttt
    15841 cttttctgcc ctcgaagctt tttcatactc ctcttcactc ataccgttat ctgaaacaat
    15901 gaagtctttc actttggttg gtttacttga gccaacaatt tttttaaggt cttcaaattt
    15961 ggtaagatca gcttggtcta aatttaatag gttgtcattg taaagagagc tgtcttcaaa
    16021 gccagtccgt acagcttttt ctgcataagc cttcttcagt gccgtaagca ttcggtcaac
    16081 gctaaattct ttcatcacat tcccctgttt accaaggata ggtaagaaat ttagcatgcg
    16141 ctctagtttt ttcttttgct ctgaactatt aacctttccc ttcttgctag ttagtccgac
    16201 acttccactc ataattttta aagcacggtc aggtgcaaaa tcaaagatgt agcagttttt
    16261 cttaattcca agctctgcat ggttaaaagg tgtctgtgca cggaacgctg cctgcagata
    16321 agatgtagga ctttctgtgt ttgaaaggaa aaatacccct gtccactctg gaacattaac
    16381 tcctgttgta agcttgcgaa ctgttaaggt tatcgtctta gacttagctg gattaccaat
    16441 agctttacgc accaattcta aatctgaatc actagcatgc tcactgtcac ctgtcttgac
    16501 tacgtttgca atattgtaat ctttgaatat agggtgcgtt tcgagcactc tttcaaaagc
    16561 atttgcctct ttaacccccg gcatcagcca taaagtatgc cgtaagtttt ctctaaactc
    16621 tggttttgag aaaggaaaat tagtcttttc atcgtttgta gtaatataat caagaaactt
    16681 gcgtacgtca ccttcatgaa gcaactttgt ttcatcatct tccttaaccc taaagaattc
    16741 tcggaagtta aatgccttat tttcatcgaa ataatcaaat ttatttggta tttcaaaggt
    16801 gaacatagat actttcggta aaccttcgta tgggttaggt tcattgggat gctctactga
    16861 ccatttctcc ttagcttctt gctccatagt ataatcccaa gtgaaaatat tatcctcatc
    16921 atacttatcg aaaaggttaa atggtgtacc cgaaagctct aagaccttgg tatgctcttt
    16981 ccgcaactta gcctttacgt tattagctaa ttccgtttcg tttccttcgt gagcttcatc
    17041 aataataata aaatcccagt caatcgctaa gaattcatag tttttatccc ctgcttttcc
    17101 acctgcccac tcagaaccgc gtaagtcctg aatacttgca aaatagatga aaggtttttc
    17161 ggtatcaaca aggttttgaa tcttttctcc atcttgtttt gaaccataga tgtacgaacc
    17221 atctgtgaag atttttttga aatccgtaaa ccaaccatca cttacaacag gtcgatgagt
    17281 catgataaga acttttttgt attggctctc tttaatcact tgaagagaag aaagcgtctt
    17341 accaaaacgc atcttggcat tccaaagcat ctcatctttc gttttgaata cagtcttagt
    17401 ctgctcaata gcatcttttt gttctggtct aaaattaatt ttgaactcgt caaagtcatc
    17461 tttttctgag tcaagactac ctttaccatc tttaaccgct tggattgctt tcttggcaac
    17521 gtcaactgtt acactgaacc actcattagg cttccctgtg tcatcttcgc caatcgtttg
    17581 aggattatag cccgaacgct ttaatacttc atgcacgtca tggtcacgga aaaattggtt
    17641 cttcttatta acagccaatt gcgcccaatg aaggacaaaa ggtacccccg ctgttgtcat
    17701 gtactgcttt attcttctac ttgcatactc tcttaaatac tcgctattag gagtaaagtc
    17761 tgcctcataa ttctctggta ctgatgcatc cccaatcttt tccagtcctt ggtacatttt
    17821 ccatgtgccg tcagcatcct tggcactctg gatgtaaata agtttacggt caaaggtgtt
    17881 ataggtgata acaaacatct catccgtaat ttcttccttt gggtttaacg atttatcccc
    17941 agacagattg cgtgcaaaga ctcttagcaa ggtatcaaga gtaactaaag attcgaccgc
    18001 ctctgaaaca ggtataattc cattttcatg tgctgcaaca tttccatatt ttctcaactt
    18061 atgaaataag tcagctatcg taggagtaat attatttctg accctaagct cgcgaagtac
    18121 atcaacatac ttcatacttt gctggtcaat acccacattt gaagcaatct tccgtgctgc
    18181 tacctccgaa taacgtctag ttccaatagc aacttcatta ggtatttgat taacggttac
    18241 acggtacgtg ttaattgcat ctactaaatt aggaatccca aggaagtgtt ctagcttaga
    18301 accatattta ggtaagtaat cgaagtattt agctttagat ttcaacgctg tcgtcatcaa
    18361 tttcctccat ctcttcctta taaacctcag ttatcggcat cgctacataa cgtaatattg
    18421 gatcatttga aacttcttca tcgacctcgt catcaaatga aaacaaatcg agctgttcaa
    18481 atacaggcag agctgagtat gcctctccaa actctcgtgt tacccctgaa taaatatcct
    18541 ccaaagaata ttcagttcga tttacagtga tttttttctg tccttttctt agcgtcttag
    18601 gtgtccactc actaaaaata atcggattat catctggtgt tcgttttgta agaaaatctc
    18661 cctgtttgat attcctagaa atcaaagtct ttgcactgtc ttggactttc cttttcattg
    18721 cggtaccatg ttttttcgat tgttctctgt acaaatcgtt gaatacttga aacatgttca
    18781 ttacacaggt ctgagcattg tcttcgagta actccacgcc atatagagtt gaaagcgcca
    18841 gtaaggagta attttcatac tgttctaggg actcattata ttcacgagca accattgcca
    18901 tttttctagt caaaacctca actaagaaag caccttctcc agctgaaggc tctaagaaag
    18961 tcgtctgcag ctcctcgcaa gcctctttta tgcctggcaa atccaacata tctttgacag
    19021 ttctttgcgg tgtaaatacc tcaccgtgct tctggacacg ttttttactt ttgattagtc
    19081 gtccttgttc ctcttcaacc atcaccatat cttcaaccac taaaaatcac ccatcttccc
    19141 aacacaaata accgaaacgg atgctacgaa tcggttatca ctttcatata tgggcttttg
    19201 ggcagactgc tggctagtac tgtgattgcg tgtcatcatg cccttttcct ccttacaagt
    19261 caagattttt acttgaaaaa actcgacaat ttctaattat gcttatgttc aattttaaca
    19321 catttttgtt ttttcctcta tctcaaaata aagaacaaaa tatagcttaa ctggagaatt
    19381 atagagtttg cctcttgcaa cacaggggag ttagcgaaga tgttcgtctg tcctatttta
    19441 tttttatgaa catgaaaaaa gaccaccaaa ctaggcagtc tttgacttat tattatttac
    19501 ttttagctat tcccattaaa ttttaccact cgtccctttt tcgccctctt tagatttagc
    19561 cgagggtcgt gtggtaaaag ctcattattg tcttaacgtg gtcaaaaacc tctttcctac
    19621 gtttatttga taacccatac tgacgaaaca cctctttcat tatcgcaatc atttgctcat
    19681 tagataactt ttcatcatac ccatcaatga agttctctaa tgactgacta tctaaagctt
    19741 tctttatttc aaagaacaag tcataaacag gtttatcttg cttcttcagc cagtgaacat
    19801 agccctccct gtgctctttt tcccgttcac ctgttactcc ttgctgttta ggtaatcaca
    19861 gaatgttgac cgactgactt ctatacctgt atcttcttat attctcgata aagacttctt
    19921 aatggtgagt ccttcttgat aatacttcag cccagcctgt aaaacttcgt ctggaaacct
    19981 ctttcgatgt tctgtcttgt tcgctgaaaa actcttgtac tcatcatcaa agctgagtgt
    20041 aaataccaca acaagatgtt cgtacgatag tctgaccaga aaactgactt ccttgtcgtt
    20101 tgtacccaaa ttttcatatg aagtagataa aagaactgta tacctggaaa agacgtcttc
    20161 ttttacgaag tcaatgcaca atagacgtag aataggctat cttcttcgac agttagtgaa
    20221 cctatatcgt ctgctaatag gatatccgac tttaaatcta aatatttttc ctctgatttt
    20281 ttaatttccc tcttgaaata atctattgta atttgtttat ctgaattgtt tgcaattaac
    20341 ccctgcagaa cttctctagc ttgttcaaca tcccgtatta ccatggaaat cactaggtat
    20401 caaactgagt catacgaaga caaaaacata aaaattgacc tgttaaaggg tcactgaata
    20461 acatataaaa tcaataaaac ggagtcagac acggagtcaa aaaacgctga gagtaaaaaa
    20521 tatacagtcc cataggtaaa gtgccacagg actgtatatt tttttatttc agattacctg
    20581 aaatgattcc atttactttt tatctcattt ttccctacta gttagtatca aatactctcc
    20641 tattttctca ataaactatt ttgggttaca tggtatctga aacagctaaa accttgtcat
    20701 tacagcaaaa aatcacttta tctccgtttc atttcagata catttcactt aagcggattc
    20761 ccaaaaaata aaagaaaaag aaacccctag ttagcctatg ctttctaatg attcctctcg
    20821 aaacacggtc aaaaaacaac ggggtagggt agttaataaa aagatagaaa aaccattatt
    20881 caatgacttt ctcaaatatt tcgttgtaat cagttacctt tccgttctta aataccacag
    20941 aataatcttt ttttccattt tcaagtaacc taagtggaat atctttaccg acttgctctg
    21001 acaccgcatt actgactcct gttagattag ctaataaatc tgataaagat tgagcatcag
    21061 tcggaatctc tgtatcagta tttatcgtta ttcccttatc ttcatttaca agtttccaag
    21121 taggtggtat agccgcgtat gtttttatga acgtatcaat ttttttatct acagtttgtc
    21181 ttgatattgt atcgtttttc ttttctacct taccaattgg actctcatct ttcgtagtcc
    21241 tataaagagt ggctgttgat aagtgttcat ccaaatttac caacacagtt aatttatctt
    21301 tttcaccgtc aataggcatg aacgttatat tgcttattcc cgtggtttcc tttaattctg
    21361 gaatcgcttt aactaattca tcttttgata tcatgattga acgaaatgta gttgaatcaa
    21421 attttttatg tcttagagta tacttaaaat ccaccatttc accatttttt tgtagttcta
    21481 ttactctgtc tttagttatt ttaaaattat agtctacagg aattttctca gcagttcctg
    21541 accaatatcc atagaaatct ttatctttat ttctacaacc tgataattga ataaccagta
    21601 tagttcctat aaccaaaaat atacctgttt ttaaataatt ctttttcatc ataaagctcc
    21661 tcttttaaag catttaatca acaatgtaag aacccaattt ttaaagctct ttaaaaacaa
    21721 tttccatcaa ttattataac attatttttc tcatctatat tagtatttta tttacaggga
    21781 atcaaaaaaa ctccttagta agcttacacc tttaggagtt cctgtttgga cggtatacat
    21841 aatacattta aatcaattta acattaacac ctcagtatat ggtatctcta catatacacg
    21901 gtctttcttt ggatagtact cgacatttat attgatagca cttccattgt ctaacgtagc
    21961 tttagcccgg tatgtgttat ctccattttc atgagtaatc gtcacatcat cacatgacct
    22021 atttaagttg tactgttctt gtaaaatctg tgtcaccaat ggtttagatg acttctctaa
    22081 tccagatgta cctgtcattt ttgaaaaaat gatacctata atagccaaga caacgatacc
    22141 tataatgaca aacttcttgt tcatatttac tttattcaac tttttatctc ctatctccaa
    22201 aataatttgc tcttatccct cttatcagta cattgacatc cctaaaagta caccaaagat
    22261 tgctccagct acccctgcta tcatcaaaat cgtacccatt ttctcatctt tttctcgata
    22321 taagtagccc ataataacag caacagcacc aaatacaaca ggaataaatg ctaacgatac
    22381 taccatagaa atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat
    22441 ttgttccttc atttcactaa atgtctgctc agtacttttc tttacttcgt ctgctccagt
    22501 tgtctcatct gtttcttgta atgctccgca aaactggcaa tacttacttt catctgttat
    22561 ttctttacca cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttaa
    22621 tagttaactg tttactttat taaacacatc agaaaacagc tcgtttattg gtacacttaa
    22681 tatctcagaa agcattttca tttgataggg tttaggaatc gttctccctg tttgccacga
    22741 acttacacat tgctgtgtaa cattcatttt ttttgctaac tccgtttgag aaagtccttt
    22801 ttcttttctg tatcggctga gattacttac ttttttcatg attctcccct cctgttttat
    22861 tatatacaac aatatgatgt atttcaactc ataaaatata aaaacttcaa ataccattac
    22921 aaatacaaca acttgttgta ctatactgag atgggggtgt attaatgaaa cagaaacaat
    22981 atgcaaaggt cattagagaa aagcgaaaag ctctcgggtg gacacaaaaa gaattagctg
    23041 aaaaaatctt ctctacacaa caggcagtag caagatggga aaattctgta acagagccta
    23101 acctcgatag cttaacagct ctttctagag ccctaggaac ccctgtaagc cattttctag
    23161 acaatgttgt cgtagattat gaggaagagt ttttggctct ctatcgttct cttagcactg
    23221 aagatgcagt tcgaacaatt gactatatga agctattaaa aaggcaagaa aatgaacgca
    23281 atcagctatt gaaagattga aaaataaata acccaccgaa ctttaacggt gggtgtattg
    23341 agatgaaata agattaagag ctatggataa cctgtctagt ttaatacaat tgggtctttt
    23401 ctcttcctta ctctccgtcc atcatctctt gttacacttg taaattgata aagaggaact
    23461 aattcaacac cagatgctat caattctttt attacttcat ctatccctgc tccttttgct
    23521 aggtagacta aaaaactact gcttgctttc acattgtata gtttcttaat atccttagaa
    23581 gctcgttcaa gagtgaatcc ttgtttaaca aagtagcctc tgttttcttt taaagcattt
    23641 tccacgctgt tattcccaac attacgtaga cgttcacaaa cagtgttaat aagttctttc
    23701 tctgtcatta gatatgtccc ttgccacgat aagtcctgta aaacttcatg tgcctcatct
    23761 aaaatcaatt gtttttcctt gctgagttct gaccgaaaat tttgaggaaa tactctttta
    23821 gcctcttttt cgttaaaaca tatcttaacc cattcataag aaaaatattg atatgtaaaa
    23881 tgaacttttt tcagaagtgg aaggatatct tcattcaatt tttgaatcac agaagttgca
    23941 ttaaaaacgt ctaatcgata gacattgctt ctcttatgat taaagtttcc taacgctttc
    24001 tcttccttta acctatttag gtattcgagc atcttcaaag gaacatcttc atcatctaat
    24061 ttttttatca atcctataaa tgtcataaat gatagtaact tattccattt atctatgtca
    24121 taagttttac catagtaaga actcattttt ttagctagtt gttctcctga taaaatacaa
    24181 gtcacacttt ccttactatc atcaaaaaaa ttaacatcag aaagcaaggc atcatagaca
    24241 cgtcgcattt cctctagata attatttatt gtcctgaaaa gcttgtcttc catagattca
    24301 agagtgtcaa aaagtacttt tgattcctct ttcaattttc gaaaatgtgt aggatacagg
    24361 tctagattct ctaatagcca attaaatgtt tctacccgac tatctttctc tagaattaac
    24421 atcacaaccc caataaaatt ttcactgata ccacaattac tggaatgaca ataaaaaatg
    24481 gaatgcccag ttttactggt aaaaatacta gcagatggat tatggtcgtc gtgaaacaga
    24541 catcttaagt ttttacttga cttaagtaat ttattcatat caatggttaa caatctttca
    24601 taaatctcat taaaagacat gtcggaggaa tcaaacaggc agtctttaaa ccactgtttc
    24661 atttcttctt tgtcgtcatt ttttatcaac ttaacaaaat cagtttcatt gactagttca
    24721 tactctctcc ctgaatcact ttgacaattt ttagaacatg tcatggtaaa atcaatcgga
    24781 agctcagtaa tatctaacat gttgtcttca ttaattatta tcactgcatc tgacttatat
    24841 cctccaaaaa acattctatt cgaagcattt acattgtcat cacacccggg tatgattttt
    24901 ttcaagtatt cgtaaacagc aatcatttta ctatagtcag taattgcttc ttttaataga
    24961 aagacaatct tgaatttttc tagattttca gagtaccgaa tacttttttg tatcgcaaac
    25021 gcagaattat gaactaaatt gatagataaa gccttttcta tgcttaagta tctactatca
    25081 tctttactta aatctactac cttccccttc tcatctttaa cagtgttatc gacatccaga
    25141 ataattactc tagtttctaa aaactcttca cttttgttgc ctttattctt tgtcttactt
    25201 ggaataaatg attgtgatga atttagtatc tctacaaact catctcttgt aacttctctg
    25261 tagttatcta aacatctttt tcgtattctc tttttttcat cctctataac tggtttctct
    25321 aatagtcttt ctttatctac attaattgga atattaatca ttggtgtttc catttgtgtt
    25381 tcctccttat aaaattctgt taaagactaa aacatacaga taataaacac aaactcttta
    25441 ttactatatg ttttagtctt atttgtttac tcaaccttta tactgttcca tgaaactatc
    25501 aatatcagat tttttgaatc taatgaccgt atcaattttt ataacaggta acccgtattg
    25561 agaaacatat tttctaatcg ttcctactga tacacctaga tattcacttg cctgctgata
    25621 gtccatatac tctagagtaa caccagaaat aatgtcttct agcataggct ttagcactgt
    25681 aattatctct ttcacttgtt gttcaacttg tatagaaaca atgctatcaa tgatttgtag
    25741 agacatattt ccccctcctt tcgtgattac ttgaacaaat tttctaagaa tcatcttcgt
    25801 attatttgat caaaataaaa gtattttgtt gttattaacc gattaatcaa ataaaaaatg
    25861 attatcagtt catcgacata cacataatac ctcgatacaa aaggggtgtc aatatgttgt
    25921 gtgaatttat ttacaacacc ccctttttga ggtatactaa ttttaggagg tgtggtcaat
    25981 atgataaagc gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata
    26041 aaagctataa gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaat
    26101 ggtcaattga ttgacaaaaa aactatctac gaatgggaaa agggaaccta tttaccaata
    26161 ccagagcgat tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt
    26221 ggcaatgtag aagaatatat tttgggaatt attctttata gagatagcat tgtactagat
    26281 ggtataacat ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta
    26341 cactctaatt tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa
    26401 tttattgcta acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc
    26461 ttaaaaatag aagaattatt catcaatgct attatagaag aatttgacaa taacattctt
    26521 ctgctcacta gcagtataga ggaacaacta gaagaaatga tagatgaagg gatacatagt
    26581 caagtggaag acatgaatta tcccgaagaa gctgtaaacg aaattattga taatataaac
    26641 aagctaaaac aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga
    26701 ggtgatacca tctagtggta agtactcctt gtaaactaag aggagatgat ttcatggcaa
    26761 aaatatcaaa gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg
    26821 ccaccgatcc acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac
    26881 aagaagctca aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga
    26941 aagcacctga tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca
    27001 gtgttaaagc ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag
    27061 catttggtaa gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg
    27121 aatggcacag taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac
    27181 gctacggggt tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac
    27241 gaaaaaaaga gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac
    27301 tggatgcttt taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat
    27361 acacaggtat gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta
    27421 ataaagaact acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc
    27481 aatctccgaa aacaagagct tctagacgag ttatctcttt agatactgag actctttcta
    27541 tcctcaacaa ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta
    27601 gctctaaaga gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg
    27661 ttaatgattg gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg
    27721 ggtttagaca tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc
    27781 aacaacgatt agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa
    27841 ataatgcacc taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga
    27901 gctggtcaaa agctggtcat ttctagtata tagacaaaat aaaaaagcta gaacccttat
    27961 ataccaagga ttctagctcc tataacaagt ttatcctaca ctgccttcca tctcataact
    28021 gatcaatcga ttgagttcga ctgcatattc cattggaagt tctttggtga atggttcaac
    28081 aaagcccatg acgatcattt cagttgcttc agattcggtc aggcctcggc tcatcagata
    28141 gtagagttgt tcttctgaga tttttgagac tttggcttcg tgttctaaag agacttggct
    28201 gttgtggatc tcattgaatg ggatcgtatc ggatttcgac cattcgtcca tgatgatcgt
    28261 gtcacattcg atatgagaga tcgaacccgc actgtttttg gcaaaggtta cttgtcctcg
    28321 atagtttact tctccgccgt cttttgaaat tgatttagag acgatagagc tagatgtatt
    28381 tggtgcattg tggatcattt ttgcacccgt atcttggatt tggtttgctc ctgcaaaggc
    28441 gatggagagc atggtgcctc gtgcaccttt tccatctaag taaacacttg ggtatttcat
    28501 cgttgttttt gcacctaggt ttccgtcgat ccattcaacg gttgcgcctt cgtatgcttt
    28561 tgctcgtttg gttactaagt tgtacacatt gtctgaccag ttttggatcg ttgtgtaacg
    28621 gcaatacgca tcttttcttg taaagatttc tacgatggcg gcatgcaggc tgttacttga
    28681 ataagtaggt gccgtacaac cttcgacata gtggatgctt gctccttcgt caacaatgat
    28741 cagcgtacgt tcgaattgcc ccgtgttttc cgcattgatc cggaagtacg tttgtaatgg
    28801 aacatcgact ttgacggctt ttggcacgta aataaaggtc ccacctgacc atacggctga
    28861 attcagcgct gctaatttgt tgtcggttgg cggtacaagt tttgaaaagt actctttgaa
    28921 taattcaggg tattctttca aagcagagtc agtgtcagta aagacgattc ctaacttttc
    28981 gaattcatct ttcatattat ggtacacgac ttctgattca tattgtgcgg aagcaccggc
    29041 tagataagct cgttcagctt ctggtatacc aatcttttca aatgtatctt tgattttttc
    29101 tggtacgtct tcccagtcac gagcgggttt gtcacttggt ttttggtaat atttgatggc
    29161 atcgaaatcg atgtctgaaa ggtcggggcc ccatgtttgc attggcattt tgttaaatgt
    29221 ttctagagat ttcagacgga attcaagcat ccattctggt tcgcctttga ttcttgacat
    29281 ctcacggatc acttcttctg tcaagccttc tcctgtactg aaaaccggtt cgacatcatc
    29341 gtgaaacccg aatttatatt cttctaattc tggtacgccc atgttctcac tcctcttcct
    29401 tgtggtaatg atggaaagct gcggtaccat cgttttccat tgcttttcct agtgctttcc
    29461 aggcaagtgt cgcacatttg atccgagcgg gaaatttagc tacaccacca agcatagcag
    29521 catcgcctaa ttggtcggga tctttgactt cttttccttg gacaagctgt agaaagtcta
    29581 cagttaaatg ttctgcttct tctattgatt ttccgatgac ggcgtctgtc atcatcgagg
    29641 cacttgccgt actgatggag cagccactgc cgtcaaaggc gatatttttg atgattccgt
    29701 cttttacatc gacttgcaat tcgatcacat ctccacatgt ggggttgttc aattcgatct
    29761 tgcttgtcga gtcagtcaag cttccacgat gatgcggatg ggaagaatga tccaagatca
    29821 cttgacggta taaattgtct aatttagata gtcccatgtt ggaaaaactc ctttgttgcc
    29881 atgattgctt caactaaacg gtcggcgtct tgcgttgtgt tgtagaaata aaagctcgcg
    29941 cgagcagtcg ctgatacttc aaggtacttc aatagcggtt gcgcacaatg atgacctgct
    30001 ctgacggcta ccccttccat gtctaaagct gtcgcgacat catggggatg taacccatcc
    30061 aaattgaatg caacgactcc tgtccgaaaa ttcgggtctt gtggaccata aacagtcaat
    30121 ccatcaattg cttgtaattt tggcaacaca taagcggcta gttcttcttc atatcgatgg
    30181 atattgtcca taccgagttt ttgcaaataa tcgattgcat ggcctaatgc gatagcgccg
    30241 gcgatatttg gtgtccctgc ttcgaatttc caaggtagtt ctttccatgt actgtcgtat
    30301 aattcgacaa aatcgatcat ttcgccacca aattcaacag gttccatttc ttctaaccat
    30361 tttcgtttac catataaaac accaatacct gttggtccgc acattttgtg tccgctgaaa
    30421 gcaaagaaat cacagtctag tgcttggaca tcaatggcca tgtgcggggc agattgagca
    30481 ccatctacta cgatgacccc gccgttttca tggacaagtt cagctaattc ttgaacagga
    30541 ttgaagacac ctaagacatt ggatacatga gcaatggaga cgattttggt tttgtccgta
    30601 atctttttcg ctgcatcctc catatccagg aagccttctt ctgttagttc gatatatttc
    30661 aagacagcac ctgttcgttt tgccaactgc tgccacggga taacattaga atgatgttcc
    30721 atgtaagaga gcactatctc gtctcctgct ttgatatagc ggtcgccgaa ggttctggct
    30781 acccaattca agcttgtcgt cgtaccacga gtaaacagca cttctgctgt ttcttttgca
    30841 tggatgaacg cccgtacttt ttctcttgct tgttcataat catgggtcgc gcgttctgct
    30901 aacgtatgga caccgcgatg aacattggcg ttatcgtgtt cgtaatagta cgctaatgcc
    30961 tggagtactt gttttggctt ttgggtcgtc gctgcattat ccagataaac taaaggttca
    31021 tcattgacgt cttgaaataa gataggaaaa tcattgcgta gctttttagc atcgatcatc
    31081 cattcaactt cccttcgatt acttcgacta attctttccg aacttgttct acagggattg
    31141 ctgttaagac agaaccgagg aatcctcgaa tcactaagcg ctctgcttct tctttatgca
    31201 atcctctact catcagatag tacatttctt ctggatcaac tcgtcctaca ctggcagcat
    31261 gtccagcagt tacttcgttt tcatcgatca aaagaatagg attcgcatca ccacgtgctt
    31321 tatcagaaag catcaagaca cgactttctt gttgggcatc tgcacctttt gcccctttca
    31381 agatgtggcc gataccatta aaggtcaatg ttcctttttc tcggatcact ccgtgttgca
    31441 aaatatgccc gatcgtatga ggggctttat tggttactcg tgtatcgatt ccttggattt
    31501 gtctgcccga gctgattgcc acgattttga cttctgcgtg tgcaccttct cctgctaaat
    31561 ctgagtcaaa gtcagcgatc acatgaccgt cattcatgac accaattgcc cagtcgacag
    31621 aagcatctcg taaaatgtgc ccacggcgat tcatataaga agtaatattt tctcctaatt
    31681 gatctacggc tgaatatttg atttttgaac cagctttagc gatgacttcc acgatgatat
    31741 tacctgatga ttttgctact tgttctttgg ttgtctggaa acgttccaga taagaaaatt
    31801 cactatgttc atctgccacg atcaacacat gcttgaagaa gtgctcatcg gatgcgccat
    31861 cttgaatgaa taaggactcg agtggttcat cgatcacgac atttttaggc acatacagga
    31921 aaataccgct gttcataaaa gctacatgga gtgcagtcaa ttggtcttcg ttcatgttta
    31981 ctgctttttt catataatat tcttggacta gttctggata ttcgatcatt gcagtgaaca
    32041 agtcggtaaa aatgactcct ttttctgcta attccacagg cagttgttca aaaatcgtcc
    32101 atgaaccttg ttggacaagc acaggattgt ctttcattgc atcaaatgcc ggaatcgtgc
    32161 ctgtttcact gatggtttgt gtttctttca catcaaataa cgaccagcga tggaatttca
    32221 cccgatcgat atgcggcaat ggcagttcat ctgctttcgc tagtgcgtct tgacggaagg
    32281 ttctcatcca atcaggttcg cctttactta aagaaaaatc atttaccgcg tcaagataat
    32341 cgagccagtt tttttctttc attcttgctc ccccttacgc ttcttcttct ttatagtcga
    32401 ttcctaattc tttactgata ccagcgtagc cttctgcttc cagacgttta gctaggtcag
    32461 cattccctgt catgactact cggccttcca tcatgatgtg aacgacatca ggtgtgatat
    32521 agttcaataa tcgttgatag tgggtgatga tcaatgcacc gaaattgtct ccgcgcattt
    32581 catttactcc tttagcaacg actttcaaag catcgatatc cagacctgaa tcgatttcgt
    32641 ctaaaattgc aaatgtaggt tctaacatca acaattgcag gatctcattc cgtttctttt
    32701 ctccgccaga aaaaccttcg ttcagataac gttcagccat ttcttctggc atatttagta
    32761 aagccatttt ttcatctaac tttttcaaaa atgccataac agaaattttg tcgttttcat
    32821 cacgtttcgc attgatcgct gcacgcatga attccgcatt cgtgatacct ggtatctcac
    32881 ttggatattg catagctaaa aataagccaa gtcgcgcacg ttcatctact tccaagtcta
    32941 aaacattttt cccgtcaaac aaaatttcgc cttctgttac ttcatagttt ggattgccca
    33001 tgatagcggc agataaggta gattttcctg tgccgttagg tcccatgatg gcatggattt
    33061 ctccggtttt cattgttagg tttacgcctt taaggatttc tttttcctcg atcgacacat
    33121 gtagattttt tatttctaag acagacatgc attatacccc caaattctct ttcgttctca
    33181 ctcattttag actaattgag aatgaagcgc aatgaccttc cttactaaaa tcaaatatct
    33241 tttatttatt attaaacaat tttgatttct aaattagaat aggtataaaa aagatgagaa
    33301 ataagccatt acagacttat ttctcatctt ttttgttcca taccttattt tgcatcagcc
    33361 tttactggtt taacagagcc gccccatttg tctgtgatcc attcttggac ttctttgcgg
    33421 tgaagcactt caatcagttt tttgattttg tcactgtctt catcaccttt acgagtcgca
    33481 ataatattca cgtaaggaga gttgtccttt tcaagcaata cggcatcttc taatggattc
    33541 aaccctgcgc cgtaagcgaa gtttgcgttg attgcaacta ggtcaccttc atcattttgg
    33601 tacgtagaag ctaaaagtga tgggtcgatc gtatggttga acttcaagtt cttagggttt
    33661 tcttcaatat catcgaatgt tgctgtttcc agatctactc catctttgac tttgactaag
    33721 ccagcatctt gtagaattgt gatgatgcgt ccccagtctg attcagaatt tgaagtaatg
    33781 attgttgcac catcttttaa ttcggaaaca tctttgactt ttttagagta caagcccatt
    33841 ggttcgatgt ggacagcacc ggcattgaca aagtcatatc ctttttcttt gatttctttg
    33901 ttcaaataag gaatatgctg gaagtaattg gcatcaatgt cgccttcttc caaagattgg
    33961 ttcggtaata catagtcatc gaatttgacg atttcaagat cgattccttc atctttcaat
    34021 aatggtttca catgttccaa aatctctgcg tgcggtgtcg gtgaagcgcc gactttcaat
    34081 gtcgtgtcgt ctgctttatt tgctgaatct ttgctgtcgc tgttgttacc gcatgctgct
    34141 aatcctacag tcagcaaaag cgctgctgca aatccaaaaa ttttcttttt catatcctac
    34201 atccccctat atcctattat cttttgtctg ttttcttagt taagaaatca ccgattcctt
    34261 gaacgataaa tacgattagt aaaataatta aagtcgcaac gaatgtcact gttagattac
    34321 cacgctggta gccttcctgc caagcaagac ctccaagtcc acctgcgccg atcgcgccgg
    34381 ccatcgcagt aaatccgatc atcgagatcg ttgtaactgt taatccagaa atcaatgcgg
    34441 gaatactttc aggtatcaag accttccaga tgatttccca gtaacttgct cccattgcat
    34501 ctgctgcttc cagtacacca gggctgactt cacgaaaagc aatctctact agacgggcat
    34561 aaaatggtgc tgcggataaa acaagagctg gaatggctgc ttgcgcacct agcatagtgc
    34621 ctacgattgc tttagtaaat ggaatgatca aaaccatcag gatcataaat ggcgttgacc
    34681 ggaaaatatt actgatgatc gatacgattc cataaatgat tcgagcatac ggtttgtttt
    34741 tgcgtccaat agagtaaagg atcaatccca aaactaatcc gatgatcgtc actaagacca
    34801 ttgagattaa tgtcatatat agtgtatcaa ggatagcctg attcatcgtt tccgggttga
    34861 tttgtttaaa atctagatat gtttctgaaa agcttttatc cacgatggat cacctcaatt
    34921 cctactcctt gttctttgat gaacacttct gcttgatcta attctttggt ttcaccagtc
    34981 atcaagacag tcaatgaacc aaaggaacct tctttcactt gtttgatctt tccatacaca
    35041 acgttgacat cgatgttata gcgtcgaatc gcttgggaaa tgactggctc gttggcattt
    35101 ctttcgctaa aggtcaaagt tgccaaacgg ccgcttggat tttctttgat gagttcagct
    35161 aatagttctg tcgaatcagc ttctggttcg atgtcttgtt gtacaaagcg tttggttact
    35221 tcttttttcg gttgtctgaa gacagtcaat acgtctcctt cttctacgac tttccccaac
    35281 tccatcacag cgactttgtt gcagattttg cggatcacat tcatttcatg tgtgatcaag
    35341 acgatggtca aattcaattt cttattgatc gctaacaata agtctaatac ttcttctgtt
    35401 gtttgcgggt ccaatgcgct agtagcctca tcacaaagca ggatctcagg atcatttgcc
    35461 aatgctcgtg cgataccgac gcgttgtttc tgtccgccgg aaagttgtga aggatatgct
    35521 tgtccgcgtc cttctaaccc gactaaacgc aacagttctt ctgcccgttc tttacgtttg
    35581 ctctttggta cgccagctaa ttccagcggc agctggatat tttcaagtac agttcttgac
    35641 cataacaggt tgaaatgctg gaagatcata ccgattttct ttcggaatgt acgtaattct
    35701 ttgtttttta attttgtaat atcttgatcg tttacgatca cttcgccgct cgtgggaagc
    35761 tcaagtccat tcaggagacg gactaatgta ctttttcctg cgccagaata gccgacgatt
    35821 ccataaatat cccctttttc aacgtttagt gaaacgtcat tgacggcttg gatgtttccg
    35881 tttttcccat tgaatgtctt tttgacattc gttagttgga ttaatgacat gccattcaca
    35941 tctttctctt atgatttttc aaacaaaaaa gccttcgccc tcttgcctta agcaaaagga
    36001 cgaaagcttg aacttccgtg ttaccacctt gatttaccgt tacttcgcaa taacagcctc
    36061 ttccagtact tggacttagc ttctttccgt atactgtcgc gctgtaacgg gcactcccgt
    36121 agtaagtttg cttacgctcg cttactctgc tctaagacca tcttccatct cattttcgtt
    36181 acccattttc agcaaacagg gctctcttca aacgtccgtg acatgtactc ttcttttcaa
    36241 agctttctcg tttcatatag gattgcttat gattatagca actggaagaa tcagtgtcaa
    36301 cttttttcaa gtgattttct gattttataa ttcgtcaaat tcttttggat caacatcttt
    36361 gaaacttaag atccacgcat tcatttcatc tgaatcattc aagatattga tatcttcacc
    36421 gattttatca ttaacagaag aaactgtacc cgttagcggg ctggcaaatt cattgaccgc
    36481 tttttccgct tcaacttcga tcagaggttc atcttttttt agcgattgtc ctgcttttgg
    36541 cagattggca aacgtgatgt ctccaagttc ttcttgcgct tcatttgtca aaccaacaca
    36601 gtattctttt ccattaaata agatccaaag gttgtccttt ttcttcaaat gcttgcctgc
    36661 cattttatat cagttctcct tcataaattt tttcattgaa tccaattgca acaagctggt
    36721 cctctcgtaa gatcagtggt cgcttgatca gcataccatc tgtcgataag acttggctcg
    36781 cttttgaagc cgtaaactcg cctacttgat ctttcagtcc aagttcccga tatttcatcc
    36841 cgcttgtgtt gaacaggcga cggattggta cttgactcgt ttctagccaa gtctcaatcg
    36901 ttgaggcctt cggtacttct ttgatcatat caacggtttg ataactaacg ccatgctggt
    36961 ctaaccacgc tttggctttt ttgcatgttg aacatttcgg gtaccagtaa aaggtgtaca
    37021 attttcttac ctccttgaag atcttgcagg tgcttcattt tggtatctca tcgataatat
    37081 caacccgata ccgatcatgt tccctaaaat cgaggatcct ccctgactaa tgaaaggcaa
    37141 tgggatccct gttaaaggaa gtaatccgat atttgctcca atattctcaa agacatggaa
    37201 cagcagcatc atgatcaaac cgcttgcgat ataggcgtaa aattcattat tcgtatcgaa
    37261 acacacccga atcatacgat agattaaaat aaaatacaag aaaatgacga atgcaccacc
    37321 gataaagccg aagttttcac cgataacggt aaaaatcata tcggactcac gaacaggcac
    37381 atagatattg cttacgttga atcctttacc aaacaagcca ccggtaccaa ttgccaaaag
    37441 tccttgggcc ggctgataac tcattcctga cgtatcatgg aaagggtcca gccatgaatc
    37501 aatacgtgca aactgataag atttgaatcc aactttataa agcaagtctc ttccgccttc
    37561 agtcgtaacc aagaagatcg ttcctgctcc aacgactact gccaagatta ctacaggtgc
    37621 gatgatgcgc caagagattc cagacatcag gaaaatcccg ccaaagatcg caagaaagac
    37681 aagcatcgtt ccaaagtcat cttgggccat gatcaatgct aaaaccggta ttgtcacgat
    37741 caagagcttc ccaatcagcc aaaagtccga tttcatcgtc cgttctttta cttgcgtatt
    37801 atgtttagtt acgatcagtg ccatcatcaa gatgtacgca atcttcatca actctgctgg
    37861 ctggaaagta aacgcaccga atcgaaacca gtttttagac cctgttgaag cagctaaatt
    37921 ctgatcatag aatttgagca agagtcccat taccactaac cccaaaccat aaaggtaagg
    37981 agtcagtttc cagatccatt tggaattcaa atgcatgatg acaacgattg ctgccgctcc
    38041 aactaaatac cagacaactt gcatccctac gcctttcaag actgctggat tgttcggatc
    38101 atggctaagt gctacatata atgagagcag accaatcaaa cataacagaa agactggtaa
    38161 aatcacgcca taatcaatac gattatcgtt cgaagctttt aatttttttt ccatgtttca
    38221 tcccttttct taaaaaccat actgctgatt attatagcgg tccagttaga taatggaaag
    38281 tctttccata gacatttggg aaaaattaac tttccgtttg tgcagttgct tgagcaaatg
    38341 cagtacaaaa gcctactgct tatctttagt gtatcataga actttttttg atacatgcaa
    38401 ttatctacca gctgagattc tcctcgctgt gagaagtttc tgtgctttca ttgtatcgaa
    38461 ggatctcttc ggcaatctct agcagctgat cagaaaccag attggttcgt tggatgaaat
    38521 aaaaatatcg atggaaattc aacggagtca ttggcacatt ttctggaaca gagcgcttag
    38581 acaaaatcga gcgaccgatt ccttccttca gcaacgcaac aattacatcg ttacttttca
    38641 cgatcatctt cttatcttgg atattcatct cttcaaaata acgctgcgtg taatgaaaaa
    38701 caccagagtt tgcttctctt acaagccaca atttgctttt tgggtcccca gcgatgacta
    38761 gctggtcttc catcaaagag tatctttgta cgccggaagt ctctaatggc ttttcgataa
    38821 aaccaaaatc ggattcatgt ttcgctactt gttctaatga ttcatgagaa ttcgtgattt
    38881 cgatctcaaa atgcacttta ggaaaccttt tgatcagatg tttcatcaac tgaggcaaaa
    38941 gatagacagc aaaggtgtgg gaagcaacga tccgacatac ttcttcttca ttttgttcat
    39001 tgagcaattt ttgctgagtt tcttcccatt cttctaacaa aaccagtgtc cgttcatata
    39061 ataagtcggc ttgcttagtt ggaagcatct cttttcttcc gttacgttga aaaagatcga
    39121 tattcaattc ccgctccaac tgtttgattt gattcgagac tgctggttga gataaaaaca
    39181 gtacttctgc tgctctggaa aaatttcttg tttcatatac tgctcgaaaa gtcgttaata
    39241 acttaaacat ggcaccactt ccataacttt ttatgataat tactataaaa actatttgat
    39301 ttaaatatac aaaaaaccat ctataataga aatgtacaac aaaacagttg ctgatccaac
    39361 tagtaactta gatgaagaca atcagctgtc tgcttgctcg taatcataca ttcctattca
    39421 ttttacaatg tattcgttca tcttggtact aaaatctatt aaataaaaag gagaatatta
    39481 tatatgaaga actttttgaa aattattccg atcccgatct gcgggttgat ccttgggtta
    39541 gcttcccttg gaaatctgtt taaagactat caccatgttg ctttaggcaa tctaactggc
    39601 ggtatctcta tgattcttat gatattcatt tttgttaaat tgtttatctt attcgaacac
    39661 acgaaacaaa cgttgcatga tccaatcatc gcctccgttt caccaacttt tacgatgtca
    39721 ctcatggtta tttgtactta ttttgtttca tatgaaagta ttgcaccaat tgtcaaattc
    39781 atttggctgt gcgctgttat cttccaagtg atccttgtct tttatttcaa ttatcaccat
    39841 gttatcaaag ctgatctttc aattgaagca atttatccaa gctggtttat catttacgtt
    39901 ggatttgggg tcatcactgt aactgccggg aacttcttcc cacttattgg aaaaattttc
    39961 ttttggattt cattgatctg ctatgcgttc ttattgccga tcatcatcaa acgtgtcttt
    40021 ttcgtaagaa atatggctca tccgacacgt ccgctgatta cgatcgttgc agcacctggt
    40081 tctctttgcc taacaggtta tcttaaaaac tttgctgaac ctaattttta tcttgtcgta
    40141 gcattgttcg ctttatctca agtattgtat ttcgttgtgc tgtctatgct tccacgtttg
    40201 ttcaagcttc gtttttatcc aagctatgca gcctttacat tcccgcttgt tatctctgca
    40261 acagctatat ttactactgt tcattacttc aacagtttag gtatctatag tagcgtattg
    40321 gatttcttaa aagttgcgga atgtctgttt gcaagtgtag ttgtcttcta cgttcttgct
    40381 cattacgtac gtttcttaat taaagaacat agcaaacatg gaaaatttgt ttctaaaaaa
    40441 atcgcttaat aatcgattca ataggttgtg aaaaagctgt tctgcatcaa gtaataagaa
    40501 cggccaaaca aaaacagctg ttcatgtttt tgtactggtt gggcttatta ccgcagatgc
    40561 aagcttttga acaccgttta ccaagaggtc gtaaaagaag tggtcagctt caagaaataa
    40621 gaaggaattt acgaaaattg cttctcaaat ttttgtgaaa tttcggctta tttccgtaga
    40681 agctacttct ggaacaccgt ttattcgaaa caagaggtcg tacaagactt ttgtcacgac
    40741 ctcttgttct tttgtcaaaa tactggttta gtgctactat gttcgagtat gcttttagta
    40801 tttattgacg aaaggaaccg atcaaatgaa atcattgtca catccaataa aatctgtaaa
    40861 ggattcagcg gtccgcgaaa tcttacccgg tttactgctt tcttttgcca tcgctgcctt
    40921 cagcaggctt cttgctattt atctgccaca gttaggtgga gcgactattg ctattttatt
    40981 gggtatttta ttaggaaata ctttttttaa acagcctgtt ctagcaatcg gcacaaaatt
    41041 tgctgaaagc aaactattag aattctctgt ttttttacta ggtgcaactg tcacagctca
    41101 aacgattgct caaattggtg taaaaggaat tgtttttgtg ttactgcaaa tgtcagtcac
    41161 tatcatcggt gcttacttga ttggtaaaaa actgcaattc agcgatactt cttctttgat
    41221 gatggctgga ggaaacgctg tttgtggttc ttctgctatt gcttcaatcg ccccttccat
    41281 ccatgcgaaa gaggaagaaa aaggacagat catcacacta gtcaatctac tgggtactgt
    41341 gatgatgttg actctccctt ttcttggatt acagttgttt ggtggaaatc tcattgaaaa
    41401 aagtgcactt ttgggtggta cactccaatc tgttggtcaa gtagtcgctg gggcaagctt
    41461 acttgacaat tctgttgtcg aattcgccat gctatttaag attctacgta ttatgatgct
    41521 cgttgttgtt gtctatctgt ttgaaaaatt catgcacaag aaacaaccag ctctgtttga
    41581 aacgccaact gatacgcaga aaaaacgaaa attaccgctt ccttggtatg tattagggtt
    41641 tgtgatcttt tgtttggtca acagcttgtt ttctttacct gtagttattg accaatcggc
    41701 acattttatc agcagctggt ttgagatcac tgctttagcg gcaattggtc tgcgtttaga
    41761 ctttgcaaaa ttcatgaaag aaggtacacg cttcttatct tatggattag ctgtcgggct
    41821 tctccaaaca gtgatggctt tactatttat ttggctgatc aaagtttaga atgaacatga
    41881 aaaaacagtt gtgattctcg catggaacaa tgtccgaatc acaactgttt ttaattttgc
    41941 agatatcctt ctaacaacaa caattggcgt ttgatttcaa ccccatctat tgcgtttccc
    42001 atatatcctg tcagttttcc attttgcccg atcactcgat gacaaggaat aacgattggc
    42061 aatggattgg ttcgatttgc ctgcccaatc gctcgcacag ctttcggact atcaacagca
    42121 acggctactt ctttatacgt tcggatttct ccataaggaa tggtcgacaa agctttccag
    42181 acattttgct gaaaaggcgt acctctcttt atagataaag gaacatcaaa ttcttttctt
    42241 tttcccgcaa aatattcttc aaactgttct tgtgtgcgcg ttaaaattcg ctgattcgct
    42301 gattcgcttt ctgaaattgg ctgaaaagat acagcagtca atccggattc atctgcatct
    42361 aaccataaaa agccgatagg tgtgtgtatt ttcattttgt ttgctcctag tcaatagact
    42421 ggaacttcct cctttttctc tatccaaaac tacttgccaa ctaataaaaa ttgttcttaa
    42481 aagtttgata aaccgaggaa acatggtaaa ctaaatacgt tagtttacaa aaagaatacc
    42541 tgttctttta cgtaaaatca aattttaaag gtgttattta aggtttatta aattttgaat
    42601 gtaaaccata tataaacata cgattgaaag gatagaaacg atgaaagtat caattgttgt
    42661 cccatgtttt aatgaagaaa aaactgttcc tctttttttt gatgaggttg aaaaattcaa
    42721 aggtgcccat gagttcgaat atttgtttat tgacgacgga tcaaaagacg gtacgttagc
    42781 agcaatcaag aagctagcct cagcttatcc ttatgtccgc tttgtctcat tttccagaaa
    42841 ttttgggaaa gaagcggctc tgtacgctgg attgcaagct tctacaggag atttagtgac
    42901 cgtgatggat gttgatctgc aagatccgcc cgaactgctt cctgagatga tcaaccggat
    42961 cactacttct gatatcgatt gtgtcggcac ccggcgttcg actcgtgaag gcgagcctgc
    43021 gatacgcagt ttctttgcga aaaaattcta ccagttgatc aataaaatca gcgatacaga
    43081 aatggtcgat ggcgctcgtg atttccgctt gatgactcgt caaatggtgg atgccgtcct
    43141 agaattaaca gaatacaacc gattttcaaa aggattattt agctgggtcg gatttaaaac
    43201 agaatatatt tcttatgaaa accgcgaacg tgtggctggc gaaacatctt ggtccttctg
    43261 gaaattattc aactactcga ttgatggtat cgtgaacttc tcggatgcac cgttaacgat
    43321 tgcttcattt atcggcgctt tgtcttgtgt cggttctggt attgcaattt tgttcattat
    43381 tttgcgggca ttgttgtttg gtgatcctac atcaggatgg ccttccatgg tctcgatctt
    43441 cctgttcatt ggtggaatcc aattgttatg tcttggaatc atcgggaaat atattgggaa
    43501 aatcttctta gaaacgaaac agcgtcctgt ttatatcata agagaaacag aaaaagtgaa
    43561 gccaaatgaa ttgaagcctc accaataata tacgtcaaat gaagtaaaca tttttttaaa
    43621 tgaaaaagga ctgtgacaaa agtcttgtca cagtcctttt ttccgaataa atggtgttcc
    43681 agaagtagct tcttcggaaa taagccgaaa tttcacaaaa atttgagaag caattttcgt
    43741 aaattccttc ttatttcttg aagctgacca cttctatcac aacctctttc atatcttatt
    43801 acttcttcat tgctgctttt agtgctgctg ctaatgggct ttcttctggt tcttctgctt
    43861 gtgcatattt tttcagcaag cgtcgttctt catgtttggt cattttcttc ttctgctctt
    43921 ttttatcaag caatttttct gtcgttccat cgtatttaca acggaaataa gcaccgtttt
    43981 taccttcgat gatttccatt ttccggtgac attgcgggca tcgatgatta gagacttttg
    44041 gatcttttct tctgcggtag ttgcaatctg aattggtgca gacatagatt ttgccgtcac
    44101 gtgtgttttt ctcgcgcaga ttggccccac attctgggca tttcttttgg gtaatcgaga
    44161 aatcttgata ttcttgtttg cttgatttga tctcattcac caagcgtttt gtttcttttt
    44221 cgattccatt caagaaggtt cctgcttgtt tctttcctgc agcaatagct tcaaggtctt
    44281 tttcccagct ttctgtcaaa tctggtgtta ctaaagaggg atttaccaat actaataatt
    44341 gcttaccttt aggagatact tgcagtcctt gaggggtacg ttccatcagt tcagatttga
    44401 ttagtttctc gataatctct gcacgcgtag ctggggttcc cagactgtat ttttccattt
    44461 gaccaagcaa gcttgcttct gacaatggtt taggcggtgc agatagttct tttttgatgg
    44521 cgaaatcggg attgattctc attccttttt cccatttgac tgtttccgtc tcagtttcag
    44581 tttcgccttt ccatcctgct tggacgacac gattttgccg aaaaatgaat cgttctttac
    44641 caaattcaac cgtaactttt gtttggctga ctttatgggg ttgagcaaac agtcctaaaa
    44701 aacgagagac aatcatttga tagatttttc gctcttcatt acttaatttt tcataacgtg
    44761 ctctgttttc agttggcaaa agtgcatggt gatcggtcac tttactgtct tggaatactt
    44821 ttgtctgttg gacgatggct ccgtttttca aatactgctt gacctcagga gcaaagtcgc
    44881 tgactgcttg caatcgttct ttcatcgtac ttttcatgtc atttgtcaga tatttgctgt
    44941 ctgtacgcgg ataagtaacg atcttatggg tctcatacaa actttgtaca agacttaatg
    45001 ttttctttgc agaatagcca tagcgttgat tggcttctct ttggatctct gttaaatcat
    45061 aaggcaatgg cgcagattcc gtttttaatt tttcttggac ttctgtgaca gttcctttgc
    45121 ttgtactgat caattgaaca agtttttgtg cttcttcttg tgtttttaaa gcaaattgat
    45181 ttttttgaag cattttggct tgttcttttc cagcttgcaa cgtgatcgtg aaatacgttt
    45241 gtggacggaa ctgctcgatt ttcttttctt ggtctctcac taatgctagt gtcggtgtct
    45301 gcacacggcc tgctgataaa ttatccgcgt acttcacagt taaggctctg gtcacattca
    45361 atcctaccag ccagtccgct tttgcccggg caagagcaga ttcatacaat gcatcatatt
    45421 ctttcgcagg tcttagttgc ttgaatccag ttttgattgc tttatctgtt tgagaagaga
    45481 tccataaccg cttcactggt ttattgaaat gcacatactc taagatccag cgagcaacaa
    45541 gttccccttc tcttccggca tctgtcgcaa tgactgcttc tgagacatct tttcgctgag
    45601 ccagctgctt gattgctttt aattgatgtc ctgttttagg aagtggtttg attcctagtt
    45661 ttttagggat cattggcaac gtgtccattt gccagctctg ccattcctta ttcagatctt
    45721 ccggcatttt caatcctaat aaatgaccaa gggcccaagt aacgatcacc ttgggtcctt
    45781 cataataatt tttgtgcttt tgattagcac caagcacctt gcttaggtct ttcgcaacgc
    45841 ttggtttttc cgctagaatt agttgtttca taaaattcct ttctgctttc tactgtgatg
    45901 ggctgatgat ttttcaacaa cgcaagtccc ttgtattgct gtaaatcatc gtcacactct
    45961 tcacaccagc gctcatctcc gtcattccaa aaggcgctga gaaagttact ttttgcattg
    46021 atatattcat aattttgatg gatttcgttc cattgttttt cgtacgcttg tcgtgcttct
    46081 tcgaaagact cgaatgtttc ttcttcttca atatcttctt cccagtcttc aaaaaaccac
    46141 caaggctcat tgtccccgaa catggtaatt acttgataca tactcgtgct ccttctttca
    46201 gcttttctag actcatctta gtcacttttc aagaaagttg caagaatttt ctcttataaa
    46261 agggtcattt aatgaacatc ttaaaattgt tacaaatgaa tctgattgtt taaggcaaag
    46321 tagcgataaa gttattgatc atccaaaaat agctgtcttc tggatcgatt gttggttctt
    46381 ttgtaaagta tcctaaaaaa cgtaaggaaa gataaccgtg gatcatacta cgaagttccc
    46441 tgcttcgatg aactttttct tctttcgtta attgaaaagc ctcaaatatc tgcaaaatga
    46501 tctgattcgt ttcatggatt ccatctaata aaacagcttc attggtatgc ggtacactga
    46561 tcagtaactc atacactgct tgatttgaaa aagcaaagga tcgataagtt tctgcataga
    46621 tctgcagtgc ttcctgacca ctttttccca caagagcccg tcgcagctgg tcattaagtt
    46681 cctgcagaag tttcgctgtt agcgctgttt tgacatcacg aatatttttg aaatggttat
    46741 acagcgaggg agccttgata tccaagcgtt tggctaaatg ctgaaaggtt atttgctgaa
    46801 catccatctc ttctgctagt tctcgaaagc agtcgatgat tttctcttga gacagatttc
    46861 tttttttcat ttccatgttt cctctcataa aataaatcct tcactctttc agtttaccac
    46921 gaaaaagaaa gagaaaaaag agactttcat tgataaacta catattgtag tttataataa
    46981 agagctgtag atgaaaattt tcagaaagaa ggagtctaat tggctgcaag aataaaggaa
    47041 aaattattta ggaaaagaga aacttgggaa caaaacttgt ttgtcttatg gtttggaaca
    47101 tttatggctg gtatcggatt tagtttagtc atgcctttta tgtcacttta catagatacg
    47161 ttaggtaatt atagtacgtc acaattgaac ttttggagcg gattgacttt ttcatctact
    47221 ttcttggtga ctacgcttat ctctccttgg tggggaaaat tagccgacca aaaaggaaga
    47281 aaattgatgc tgttgcgtgc ttcattagga atggcaatcg tcatttcttt gatgggttgc
    47341 gtgactagtg tgtatcaatt agtcgcattg cgtctgcttc aagggatttt ttctggttat
    47401 atcagtaatg ccactgccct tgtcgcaact gggacgccaa aagaaaaaag tggtcaagtt
    47461 cttggaacct tagcaactgg ttctgttaca ggaacattac ttggaccgct tcttggcggg
    47521 atctctgctt cagcgtttgg ctatcgccct acctttttca ttacagggat catcttattt
    47581 ttcgtcttct tgttgagtct gtttttcgtc catgaaaaat ttgtcccagt gaaaaaagaa
    47641 aacatggttt ctgccaaaca gattttcaaa gacttgaaat atccacacgt cgtcatcggt
    47701 atgttcgtca caacgatgat catccaagca tccaacaatt ccattagtcc aatcatcagt
    47761 ctgtacattc gccaattgct gcatggacat gggaatgtta cgttgatcag cggaatcatt
    47821 gcttcgatac ctgggattgc cactttgata gccgctccaa gatttggtcg cttaggtgac
    47881 aagattggga gtgaaagaat acttgcgatt ggtttgggtt ttgcgattct ggtttatatc
    47941 ccaatggcat tcgtcacgaa tgtttggcaa ttagctgcct tacgtttttt gattggtatc
    48001 tctgatgctt gtctgctccc tgctgtccaa gcattgatca caaaatattc gcctcatcaa
    48061 gctgctggac ggatcttcag ttataaccaa tctttccaag caactggtaa cgtagtaggg
    48121 cctatgatcg gctccagtgt ttccagtgca tttggttatc gtggcgtctt tctttcgact
    48181 tctcttcttg ttttggtcaa cttcttgctt gtacgacaca atacacaaga gatccatcag
    48241 caagaaactg cagaagaaaa agcttcagga gtctccatag cttcagggca ctctccttct
    48301 catagacaat aagcgtaaat gaaaaacact gcttgaacag ttgtcacaga ctgtccttgc
    48361 agtgtttttg tttaggcctg ttttttcaag aactcagata agaggaataa tcccttttcc
    48421 aaggtttctt ttttacaaca gtaacctagt cgggcatgct tcggtaaatc aaaggcactt
    48481 cctggtacta atagtactcc tgtttcttct aataaattga tacaaaatgt ctggtcatct
    48541 tcttcgatgg ctaatttaat gaaagaagta gagacgtaat tgggagcgac aagttcaact
    48601 ttcggttcat tggctaccca ttgttttaaa atcacaaggt tctctgtaat gatctttttg
    48661 tttcgcgcca atattttttc tttattcttc aatgcatgta cagcaagatc atctgacagg
    48721 actccgccgc aaatcatcgt gtagtctcga tactttcgaa aaacttctgc caactcaggt
    48781 ccagtagctg tccagccaat acgaatacct ggaatggagt aggttttgga tagggaattg
    48841 gttgctatac ctttttcata gacatctacg atcgacaaga attcaccttt atccgttaaa
    48901 ggcgcatata cttcatctat caatacatat gcatctactg tacgagcaat ttctgcgatt
    48961 ttttctaaag ttttccgatc tagcaatgtg cctgtaggat tgtttgcact attcaaacag
    49021 atgatttttg tttcaggttt gactaaggct tctagctgtt ctaaatcaaa ctgccaatct
    49081 tcttcttcct tcaaatgaac aaagtcaaca gcggcaccta aagatttggg gatgtcatat
    49141 aattgctgat aagtaggaag catcgaaaca acatggtctc ctgcttccac taacgcgtat
    49201 agagctaaaa gattagcacc agtcgctcca ttcgtttgta agatgttttc cggatcgacg
    49261 gtttgataaa gagaagcgac ttcttgtttg aaaacatctg atccttcgat ccagccatag
    49321 tccaatggtt cgtttttgcg tttttcgaaa aatttactta cgctagtccc atctaagcca
    49381 acgagttcgt ctaatgtcaa tgcttcgatc gagctttgtg caatatcata taccgctttc
    49441 ttttcccatt tatttagcca ttcttctaca ccgaaatttg cgattttcat gtttctttcc
    49501 cccttatatc ttgatccagc ctacagcaag caacccgatt gaaagcagtg cggccacaca
    49561 aatcagccca atcattactt tttcttttcc cgtaatttga tgtttggttt cacgacaagc
    49621 gatccagtag aagcaaaaac caggaagata ggcaatacta cataaaagga cataagaaaa
    49681 tcctgctaaa atgatgccca tcaattcaaa aactacagca atcccaccga tcactacttg
    49741 ttttttgatt ccttctttta aagaaaactg gacttgatag atcccgacaa gtagataaca
    49801 aatcaaaatt gccgctgtac ataaagaata ggcaaattga taggcataat cagtaactaa
    49861 gaaagtcaat aagaatagat tagtcaagat tgcagtaaca actaacgaat aagttggggc
    49921 atttttttta ttcgtttttc cccaaccttt cggcaacaga ccgtctcgag ccatcaacat
    49981 cgttgtttct gctgggagca tcgtccaaga caaccaagaa ccaatgatcg aaataatcaa
    50041 gccgatattg atcagcgctg ctccccaatt tcccacgatt ccttttaaaa tatttgccat
    50101 agcaggttgt gaaatagttg ctaactcttc ttgagataag acgccgtatg gcaagatcga
    50161 agcaaggata tagataaaca ataaacaaag cagaccaatg atcgatgctt gctgggcttc
    50221 tgaacgtttc ttcgcgcggt tggctaaaac acttgcgcct tcgatcccta caaagaccca
    50281 catcataacc atcaaacaac ctttaatctg caaccagatc gttccttgct gccctgttcc
    50341 attcactaga ttatcagata cgttacccca aaaatcagca gtgaatatat tcactttaaa
    50401 tgcgataaat acaaatatta aaaataggaa taatggcact aatttacaga tcgtcacgat
    50461 tgtattgatg acgctcgctc cttcaactcc attgtttact aataaagtca gaccccaaat
    50521 aaaaatactt gcaaataaaa tagaaggaac attttgtcca cctttgaata tcgggaaaaa
    50581 ttctcccatg gcgctcatca gcatcgttgc aaaagcaaca tttcccagcc acgcagacaa
    50641 ccagtaaccc caaccactga tgaagccacc taatttacca aatgaagctt ccgcgtaacc
    50701 gaaaatacca ccatctagat ctggacgctt ttctcctaaa tgattcagcg ataataccaa
    50761 agctaaaata ccaatcccaa cgattatcca tgaaaggatc gctggccctg gagctgcaga
    50821 actagccaga tcacttgtga tcccaaacac accgcttccg attgacgaac tgacaaccag
    50881 agcaaccagt ccccatttgc taatacccgt cgatttcttt tccatttcca tcaccctcac
    50941 ttataaaatt gaacaaatca cttgcaaaag attcccttct attttgcaac tgctcttgct
    51001 taacaaaaag caactttatt catattattg gatattatga actttttaca caagtatttc
    51061 aagtataaaa tgaataaaaa ttaattttat tgcaaaaaaa cagctatgct atccaaaaga
    51121 aaaggtgttt cttttgttag ccatagctgt tttgattcat ttaatatcgc ttaaacgtat
    51181 tgtaaaactt ttgtttcttg atatgcgtgg tcgatcaaac caccacccag acattccatt
    51241 ccatcataaa atacaactgc ttgtccagga gtgattgcac gtacaggttc gtcgaatacg
    51301 acttctgcac gattatcatc caataagcga actgtcacag gaacgtcttg ctgacgataa
    51361 cggaatttcg ctgtacactt gaattctttt ggcattggtt cattcgtcgt aaagtggatt
    51421 tcacttgcat ccaagcttgt ggcatacaat gcaggatgat ggaacccttg ccccacatat
    51481 aatgtgtttg tcgctagatc ttttcctaca acaaaccagg gttcttgcga atctcctccg
    51541 ccaccgatcc ctagtccttg acgttgacca atcgtataat atatcaagcc agcatgttgt
    51601 cctttgactt caccatcaag agtgaccata tttccttttt ttgctggcag atagttgctc
    51661 aaaaattgtt tgaagttctt ttcaccaata aagcagattc ccgttgaatc ttttttctta
    51721 gcagtcgcaa ggcctgcgcg ttcagcaatt gcccgtactt ctgatttttc catgccgcct
    51781 agagggaaca tcgtttttga aagctgttct tgtgataatt ggctaaggaa gtaagtttga
    51841 tctttattat tgtctactcc acgaagcatg tggaccacgc cgttttcatc gcgagtgact
    51901 tgcgcataat gtccagtagc tacataatcg gcgccaagat ccattgcata atccaagaat
    51961 gctttgaatt tgatttcttt gttgcacatc acgtctgggt taggtgtacg tcctgcgcgg
    52021 tattcggcta ggaaatattc aaatacacga tcccaatatt ctttttcaaa attcacagag
    52081 taataaggaa tcccgatttg agcagctact ttcgctacat ccttataatc ttccgtggcc
    52141 gtgcatacac cgttttcgtc cgtgtcatcc caatttttca tgaatattcc gatcacgtcg
    52201 tatccttgtt cctttaacaa aagtgctgtt acagatgagt cgacaccgcc gctcatccct
    52261 acgacaacgc gtgttttgct gttgtctgtc atgatatcac catcatttca attagattct
    52321 gaaacatcta cgagttgaag gtcgcaactt ttcagtattt tacattatac gtcatatttc
    52381 tgaaaatttc atcccttaat tatcaagtcg taaaaatact gttctactgg acctattcag
    52441 tacacaaaca tgatagtcaa ccaaaaaatc actcatcttt tgagcattcg atataaaaaa
    52501 ttggcatact cataaaaagg gccagccttt cggcaataag gaataatttt ataaattgtg
    52561 aaaaactatt tttcaaaatt gcttcttatc gcttaaagct gcacgtctca tttacaacct
    52621 tttcttttta gatgttatga gttgctcaga taagtgattt tgtttactct aagaaaaaag
    52681 ggaggcaaaa gatacatgaa ttactttatc agtgatatgc actttttcca tgaacgctta
    52741 ttaggaaaaa acgactttgc tccgcggctc tttgcaaatg tggatgaaat gaaccaacag
    52801 ttgatcacta gctggaatgc agtaataaaa gaaaccgacc atgtttatca tctaggcgac
    52861 cttgctatgc atccgcaata tgaaaaagca aatgcagaaa ttttggaact ggtcactcaa
    52921 ctgcaaggaa caatccactt gatcaaaggg aaccatgaca gtcgcgcttt tttccgttat
    52981 ttagaaaaaa atgatcctag gcttactgac ggaagtccca aattttattt ttatgatgta
    53041 ggtgccatcg ttaaattcga ccatcaacaa tattacttga ctcattatcc gatgttgctc
    53101 gggcctaacg acactatccg caatcttcat ggacatatcc atcattacag cgtacctatc
    53161 gagaacgatg tcaatgtagg cgtagacgca ccggaaagag aactcttaaa ggaaaaacta
    53221 ccatttggca ctccgttatc tgagcaacaa atcaaagaaa tctatgaagc aaagaggaag
    53281 tacgataggt cgtgaaaaaa ctgccctata tcaagtatta aacaaataaa gataattact
    53341 catatttttc atttgagtag gcttattgcc acaggaacat taggatcaga aatggagttg
    53401 taacaagact tctgtcacaa ctccattcca tactattcgt ctttttgctc atggtgttct
    53461 tttaccagtt ttttctgtaa ttctttatca taatttcggg cagctgacgt taaaaataaa
    53521 acgattccgc ataataaaat cccgattccg gaaaacaaga acattttttc tacccctaaa
    53581 cgatcagcta atggtcctgc aaataataat ccaattggac ctgccaggtt catcaaagag
    53641 ttgaagttcc ctaagacacg acctaaaaca ttcgattcat aactctgctg gatcattgcc
    53701 atcagcagtg tattgaaata tggcgttgca caacctgctc ctgcattcaa gataagaaag
    53761 tacaagaacc cttgactatc gtttggaacc aatccgcttg caccgatcgt caggcccata
    53821 atgatgtagg ctataataat aggtttcatt cggtctttcc atgttcctat aaaactgatc
    53881 agtgcaccgc ctaagagcat tccgactgcg tagactactt ccactgctcc cgcctgtcca
    53941 acggaaccac caaagtaatc tagcgtcatc aatggataca gactgattgc tggcatgaac
    54001 aacagcatca caaatgcacc attgatcgtt atgtaccata accctttatt atccatcaat
    54061 tgctgcagcc caaattttgc atctttaaaa atagtaagcg gaacttccaa tatttcagga
    54121 gaaacttttg ggatcttcac aaaaatcaat aagccgacac caaaaactgc ccccaataca
    54181 tctaataaaa taaggtaatt gacaggaacg actgaaaaca aagccgcacc tagagctggc
    54241 gcaatgatga aattcgctga ttggaccatt cctaactgtc cattcgtcct tgttatgtga
    54301 gaagatggaa cgattgtcgg cataatcgac tggatcgttg gcatttggaa tgtttgtgcg
    54361 accgaacgca taaacaaaga cacaaaaact agccaaatcg ggaaggattc tgaaatcgtt
    54421 ccgactactg ctaaaataag cgcgaaaatc gctacaataa tatccgtgac aatcaaaaga
    54481 gcttttttat cccagcgatc cactagcggt cctacaaatg ggcttagtaa aaccatggga
    54541 atcattccta gtaaagtagc aaaactcaaa attgtcgccg aaccggtttc tcttgtcaaa
    54601 taccagatga tcgcatattg gacgaccata ctagtgattc ctgacaaaaa ctgtcccgat
    54661 aaaaagaaca aataatttct cttccaattc gttaaaacga ccgactgttc attttccata
    54721 aacatccctc ttttcttttt cattttgtat agcgtttgca caacaatcat tatacgggat
    54781 tcttttttca aaaaatacct ttttccctaa ataacaatcg tttcaattta aatttcttta
    54841 cttagaaaca ataaatcagc aaaatattaa aaataacaac atgtgttaaa tttaaaaata
    54901 aaaaagacaa ctaatttgcg tcgtccttac aaagttagtc atctaacaat aggccgtttc
    54961 aaaactagtt gtctttttat atccacagat cattcgactt tttcgaataa cccacggcta
    55021 atcatcccat ccatcagaaa ataaaattta tcttggctca ttttctgttt tggatctttg
    55081 aaaatattga ctgctttcaa tccatttgct gtagtgatcg acattttcaa tgtttgaata
    55141 tcttttgata cagtgatttt taatttgaat ccttctttgc tttgcggcgt ggcatctaat
    55201 ggtcggatca attgataatt gcctccgttt gtttctgtaa atccattatc gcgcaatgta
    55261 tatctttttg catcaggatg caaacgatag ctaattggtg cgcccagtac cgttgctgtt
    55321 gtttcaaatg ccatgatttt cacctcgata aaattagttt ctctttatta taaaagttta
    55381 tcctgatttt tactaggttt ttcagttaag ttccctaaaa aatgaaggcg ttctctcaga
    55441 catctgttca tataagaatg acttcactag ttattttttg acagcacgaa ctaattgatc
    55501 aaggaaatac tggatgtcgt cttcggtatt tcccaaacca aagctgatac ggatggattc
    55561 ttttagtatc ggtgtatctt ctccatacat tgcttctaat acgtgtgaag gctcgatatt
    55621 tcctgctgta caagctgaac cagtagaaat agcgacccca ttaagatcaa gcttcatcag
    55681 tagcaaatca tttgcttcgc caattaagcg aagattcaac acatgaggga gtttattcgt
    55741 taaatcacca tttacttgat aagggatttc gtttgcttct aatgtatcaa gaatcaattg
    55801 ctggaatcct ttatatttgt tgttacgtgc ttcacgttct tcaggtgaca gcagttcaac
    55861 tgcttttgcc ataccccaga tccctgctaa attttctgta cctgcacgcc gcttttcttc
    55921 ctgctccccg cctaaaagca atgcagggat atttactccg tctcgtttat ataagaaacc
    55981 gacgcctttt ggcccattga ttttatgagc agagatactt aataaatcga ttcctaattc
    56041 ttctggatgg atcgtttggt ttccgtacgc ttgtaccgca tctgtatgga aataagctgg
    56101 atgatccgct aaaagttcac cgatttcttt gattggcatc aaatttccga tttcattgtt
    56161 cccgtacatc acagagacca agatcgtatc ttctcgtaac gcttttttga cctcttcgat
    56221 cgacagattc cctttttcat ctacaggcag atatgtaacg tcaaacccct ttgtctctaa
    56281 atatttcatg gtattaagaa cagcaggatg ttcgatagct gtagtgatta gatgtctgcc
    56341 ttctttttga cgcgagaacg ctgtttctaa gatagctgta ttatcccctt ctgttccccc
    56401 actgttaaag atgatctcgt gaggttttgc ttgcagactg tctgcaatga tttgtcttgc
    56461 tgtttccaat ttttcatgcg cgtggcgacc aaatccatgt atgcttgaag gatttccaaa
    56521 cgtgtcttgc atgattgccg tcatcgcttc aattacttgt ggatgcatgg gggtagttgc
    56581 cgcatgatcc agataaatag ttttcacttc attcatccct tccaaattat tgctaggcac
    56641 attctagcat aaaatagcga acaaaccaaa gaagagctca tttttgtcta gaggacgttt
    56701 catgggcata gaaaaaagga gctgtgacaa aagtcttgtc gcagctcctt gaagctgctc
    56761 acttctgtca caacttcttt ccctcttttt tttgtttatt cgaattcttt ttcttccaga
    56821 cggaataacg gactcatcgg tgtattttca tggatgcgtt tgaccgcttc acccattaat
    56881 tctgaacatg taacgattgt taagttttct ggatgacgat tttcttctgt gaaaacagaa
    56941 tcagtgatac aaatatcttt gattggtgca ttgtctaaaa tacttttcgc atgatcggac
    57001 aataatccat gtgacgcaca ggcatatact tcttttgcgc cgttttcttt taatacattt
    57061 gctgctcgtg caagcgttgc tcctgtgttc aagatatcat ctaccatgat acatgtcttt
    57121 ccttgaacat caccgatcac ataaccaccc tcagttgaag catcatctgc atgatctacg
    57181 atggctaatg tgctgttcaa atattctgaa agactacgtg cacgctgaac accgctgttt
    57241 tttggcgaaa caactacgat gtcatctccc gtcagaccta attgacggta ataatgagca
    57301 aacaacggca tcgtaaataa attatctaca ggaatatcaa agaatccttg tacttgaacc
    57361 gtgtgcagat ctaaagtcag tactcgagtt gcccctgctt cttcgatcaa gttagcgatc
    57421 aatttcgcag tgatcggttc atgaggtttc gccgtgcggt cttgcctagc atacccatag
    57481 taaggcaata cgacattgat cgttttcgca cttgctcgct tcattgcatc gatcatgatc
    57541 agtagttcca tatagtaatc attgacaggt gcattcgttg attgaacgat atacacatga
    57601 tcccctcgaa tactttcttc gatattgatg gaaatctcgc catcactaaa ttgcttcacg
    57661 acgcttttac ctaattctgt tccgaacact ttcgcgattt tttcagctaa tggacggttg
    57721 ccattcaaac taaaaatctt caacgtgtca tcctgatact tattactcat gtagtcctcc
    57781 ccaaaacttc tctattcttc gatagtttaa catatttttc caagattttc tgttaatttc
    57841 agcaaattct taaggaagtg aaactgttcc gttactccaa ctggcaggaa tgactttatg
    57901 ataatcgccc cagttgtcgt gtactttgta ataacgttct cctgtttcag tttcaaaata
    57961 agcgtacgct gtcacccaat gattgccata tgtactgcca agtactttca aaataccaat
    58021 catcacaggt ttgccttcac gtatacgttt tgtagctcgc tgccatgaac ctagaagagt
    58081 tgctcgtgca cgctcatgat tgccattctt ctttaaaaaa ctagaaatcc ctgtactaac
    58141 ctgaaaagga atcgtaggaa gtcctagtgg ttggatctgg ctacgcaatg ccttcgtcaa
    58201 aaccaacgaa tcagccgtat ttttcttgcg aatctcattt ggaagcatcc accccttacg
    58261 atagtcttga taataggcaa ggagaactgc tgccgcgtaa gtaccacaaa gatagcctga
    58321 gggggtagcc catttcttat acctcaaaaa acgttcttct ggcaatccca cccagcaatt
    58381 tgcgagttcc tttcctgacc ttttttcttc gatcaaaacg ggaatatctt cttttctgtt
    58441 gatccatcta gataactcga ttggctcttc attgatcagc ttccattttt tacaagaaag
    58501 accctcttga taagtatatt ttgctggaga atattctacc ggatgtcctg attgatcgat
    58561 aatcacataa ctttgatctt caaaaaccag agctaaaaaa agcaatttac tttttcttga
    58621 ctgcagctgc tgagtgctgg ctaatttttt aattttttta tctactttga aatataaagg
    58681 tttatccact acttgattca gttgggatcg cctccttttt ttcattataa gtgaaggatt
    58741 gaaaaaaaca aatcagtttg attgttcgaa ttttcaattt tttatgttct atttgttaat
    58801 tccttcattt tgtaagataa tgggcacacg aaacaaaaaa ggagcgatcg atgaatgaac
    58861 aaagaacgat tgaaacaaga tttctatgaa gcagtcaatg aagaatggca aaaaacagca
    58921 aaaatccctg cagataaacc agctacaggc ggtttccaag atttagttga cgggatcgac
    58981 caacttttga tgggagaaac agacgatctg cttgcccatc cagaaaaagt gtcttcagaa
    59041 aaaatgaaac atttccttgc atattatcaa ctggcaaacg attatgaccg aagaaatgag
    59101 ttgcatgctc aaccgcttca acctataatc gaaaaagttg aatcattgca gtctttcgac
    59161 gaattgaata agcaatttcc agaatggctg ttggatacat taccattgcc atttaatctg
    59221 gatgtagatg cagatatgaa gaatgcgcaa acgaacgcct tctttgctta tccgccttct
    59281 ttattccttc cagataagac gtattatgca tcagaccatc ccaacggtgc acaactaata
    59341 ggcgttttct ttgatatggc tgttcagtta ttagagcttg ccggcaaaga aaaaagtcag
    59401 gcagaagcaa tcacggaaca agcagtgcaa tttgataaat tgattgctcc tcatgtaaaa
    59461 agtgcagaag aaaacgcaga ttacagcaaa atgtataatc cgcaatcttt tgatacattt
    59521 attaaataca cagataaact ggacttgaaa aaacttgtca cgggtttgat tgggacaact
    59581 ccagataaag tgatcgtaac tgatccagtg tacttcgatc atttgaatga catcctgaca
    59641 gaagctcatt ttccgttatt caaaagctgg atgatcatta aaacagtacg ttctcttagt
    59701 ggttatctat cagaagaatt ccgccaagtc agcggaatct attctcgcgt attgtctgga
    59761 acagacgaag caatgcctca gaaaaaagca gcgtattacc ttgcctctgg acaattcgat
    59821 caagtagttg gcgattacta cggaaaaaaa tattttggcg aagctgctaa aaaagacgta
    59881 gaacaaatgg tgaaaaaaat gatcgccgtt tataaaaaac gtctagaaga aaatgactgg
    59941 cttggggatg caacaaaaga aaaagccgtc ataaaattaa ataacttagg tatccaagta
    60001 ggctaccccg ataagatccc agcattattc gaccagttca aaacagtacc tgcagatcag
    60061 ggtggtactt tgctttcaaa tactcttgtt ttcagcaaac tcacattaaa agatcgtttc
    60121 agcaaatgga acaaaccagt ggatcgttca gaatgggaaa tgagtgctga cacggtcaat
    60181 gcttattatc atccatttcg gaatgtgatc gtctttccgg cagcgatcct tcaagcacca
    60241 ttttacagtc tagaacaatc aagctctgct aattatggtg gaatcggagc tgttatcgct
    60301 catgagattt cccatgcatt tgataataac ggcgctttat ttgacgaata tggcaacttg
    60361 aacaactggt ggacagaaga agatcttaca caatttcaaa acaaagcaca agcaatgatc
    60421 gaagaattcg atggtctgcc ttttgctgac ggaaaagtaa acggaaaatt aaccgtttcg
    60481 gaaaatattg ctgatgcagg cggtctaagc tgtgcattgg aagcagcaaa aacggaatca
    60541 gatctttcta tcgaggaatt ctttgtcaat tgggcaacga tttggcgtac aaaagcaaaa
    60601 aaagaatacc aacaactttt actgcaaatc gatgtccatg cccctgctaa actccgagca
    60661 aacgtgcaac caaaaaacct tgacgaattc tatgaaacat ttggtatcac ggaacaagac
    60721 gctatgtatc tagcgccaga aaaaagagtg cgaatctggt aagaggttgt gccagaagtg
    60781 gtcagcttca agaaataaga aggaatttgg gaaaatcgct tctcaaattt ttgtgacatt
    60841 tcggcttatt tttcgaagaa gttacttctg gaataccatg tattagaggt tgtgaaaaag
    60901 ctgcttagtt tcaagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata
    60961 aatttgactt actaccgaga aactggcttt tgaacaccgt ttatcgagag gttgtgaaat
    61021 cagcgtcctg acctgagtat tagagaaaaa aacggaaaaa tagttcctca tattttgccg
    61081 tttgttgagc taataccgag ggtcagctga ttgaacaccg tttagtggag agattgtgaa
    61141 aaagctgtcc tgcatcaagt aataagaaca gccaatcaaa agcagcaagg agaacctcat
    61201 ctataaaaag atagaaggaa gtgagacatc tattggtctc atttccttct atttttactt
    61261 tcctcagtca attgttttac atcataaaag gagaaattcc acttattttt ttcgctgttt
    61321 catgacataa acaactacac cgattaacaa aattcctcca gctaatgcta gcaacgggtt
    61381 attaaattct cccgtttttg ggagtccttg agtgccattt ttttcacttt cttttgctgt
    61441 cctatccgga tgagaaggtt ttccatttgg ttttccattt ggtgattcat ttcctggatt
    61501 ttctctttct ggtttgtcat ttcccggggg cacatcggca gtttctcgca cagtgatcgc
    61561 tttttgctgg gtaacagatt ctgtatgagc agaccatttt tccccatcaa atatttccga
    61621 acgataagtg acttctagcg tatattctcc ttttgaaggt gctgaaaaaa tagcggtatg
    61681 attagaaaat tgagcacttg actgtgtttc aacgatttgg atcttttctg ggaaataacg
    61741 catatcttca aagacaggcg ttccttgatt tggtgtgaaa gttgacacaa aaactgtaaa
    61801 aggcttcagt tcaatgatat ttccttctgc attctccgcc acaccatttg cttcttgtat
    61861 aataatcgga ttattttgtt catttggttt tgtctgattt ggttcttgta cgattgcata
    61921 ctctggatat tccgaagacg gtgaggtttc tccgtcaaaa atagcaccta cagataatgg
    61981 aagaccatcc actctttcct tttctgtttg acgattcccc ggtttaatct gcatcagtcc
    62041 atgaacatgg atacttccat tttcatagcg cgtaacaggc tgctgacctt ctttcgaaca
    62101 tgtatttaga gactcgatcc aatcttttga tatggtatgt ccaagagtat tttctgattg
    62161 tttctctcgt tcattccaat agtagttcaa cgagtggtag atttgatctt cgttttgatt
    62221 caatgggcgg atctgctctc tcatctcaag attctctgtt cggaaagata agataccaga
    62281 agcatggtag tctgtgtttc ctgctgaaga ggtataaaga gccacattat atgaaccgtt
    62341 attaaaactt gtactgctat tgacgataat atctgttccg ctattggaat cgattccttt
    62401 cgcaagattt tcgaaagaca aactattgat caattcatga gggcccgtta aagaagaacc
    62461 gcccattttg aatccattac cgttaccttc tccctcaatt cctggtaccc agccgtttcg
    62521 ataagcaact gagtttttga tgattacttt tccgatcgaa cctgtttcat ttttagcaaa
    62581 aaggtcccaa ccgtcatctg cattatgata cgcgatacaa ccgtcaaata catttccttc
    62641 tcctattgtc agtttggccg caaatccatc ggcatcttca aatcctggat cggcattttc
    62701 aaaagatgta cagttcttga ctaagttatg cgcgggccat gcttcgaaag gatcatttga
    62761 gctaccgctg atttggattc ctgtatttcc attccgataa gcatgaatct cttcgatcaa
    62821 attatgattt ccagaaatct gtaatccttt ttgcatagct gcactatttg taatgtcaaa
    62881 ccctcgtaaa ccccagtagt gactgaacag tgtcatccca tttccagttc ctttaaaatc
    62941 aagtacagga cgcttgtttt ctggattttt ctctgcaatc aactgaatcg ggttttctct
    63001 tgtcccgtta acgccttttg gaatcgtcaa tcctctttcg aaggaataag ttccaggcgc
    63061 catgacgatt gtctgcccag catatgcgta tctcaatgct tgtgtcagag ataatggatt
    63121 ttgtctgctt ccgtttcctg catctgaccc ttctggtgtt acataaactg tcgaatattt
    63181 aggtttacgg tagtccactg tatgaagaat ctcttttgtt tcataactag tcatctctac
    63241 gtattcttct ggcggatagt ttttatctgg cgtaaaactg aaagtaaatt cgttcgttcc
    63301 ttccatcagt tttgtctgat aatcaaattc ccgattcgca gtgatagcca agttttttgc
    63361 gttcttaagc acctctcctg ttgctttatt tttaattgtc aataatccgt cagcatttgc
    63421 tctaaaggac atagtatgat cttggtttcc tgaatgatta ctagaggtca cagtgtaaat
    63481 cggatcaatc aagcgagtag gtctttcttg cccaggagga tctgtcgcag gatctgagta
    63541 agcaacttcg attccttcta ccttgatcgt catattcctt gctgcagcaa atcctgcata
    63601 aataaccgat tcatctgaag cgtataattt ttcccagtca tacatgatgt cagaagccat
    63661 ttcttctcct gtttcaggat cgtaataata tgcctctaaa ccagtattcg tttttttcat
    63721 ctctacgtcc agtttagtaa tcgagttcgt ggccggaaac agattcccat gaccgtttcc
    63781 gaatatatta taagaacctg tttctttttc caagaaccct gctgaagtct ctaaaggtgt
    63841 tgtttccact gagacactcc caggagctgg cgcagcttgc ggatcttcag atgatattcc
    63901 tgtgattgcc cgtgtcccca atccaagtcg catcgtatat ttgctgccgc tcgtgttgac
    63961 cacttcttgt ctatccgagt cccagacata ttcgatccga ctgcctagta tggcaaatga
    64021 atttgaataa aatgcctgcc caaacaaatg attttttggt actgcgtctc ttaccattaa
    64081 agcaaatcct tcttgggcat tcgtataggt ccaagattct atttcgatcg tcgcccgcat
    64141 cctaaagttg atgtctttgg ggattgcttg ataataatag gtcattccat ctgatccgct
    64201 tgactggaat tttccgccgt tattcgtgga agagagccgc acgccgtctt ctaatggttc
    64261 aatggcatac ctactagcac ttgtgctttc tccgaaaaca acccctttcc actcttcatt
    64321 tgcttcttca gattgctttt ttgtcttttc attttctgat tctttcatca taggatcatt
    64381 tccttcttcc gtatccatat cttcactagt tcttggtatt tcctccattg ttgacatccc
    64441 ttcaatgttc acgtgtgcat tttcttcgtt cacagactgt tgttcgttag cagcaacttc
    64501 aacgacagaa attaaaaccg gggtactgag cataaggaga ttcatcatta gcgcactgta
    64561 ttttatacgt ttttttaaca agtgtattcc tcccgtaaca aattagaaag cgtttactta
    64621 aagtattacc taatttattt ttactgtcaa taaaaaacaa aattataata agtgtatttt
    64681 ataaaaagaa aaaatataac ttaagttgtt gataataaag agatttatta acgtaaaaag
    64741 aataagtttt tttaaaataa cgtataaaaa agagcataaa acaaagtcgt ttgttttatg
    64801 ctcttctttt attattttgt gctttttatt ttatcaaatc actttgtttt tttataaaat
    64861 ttctgcgcct agtgtggact caaaatgtct caatgcccat tcatgtccaa cgggatcgaa
    64921 acttgccacg gcatctttga aaatatggag tttgtatcct agattatacg catcgactgc
    64981 tgtatgcaac acacagatat ctgtacatac gccggtcaaa taaatatctg tgatctggcg
    65041 ttctcgcaaa cggatgtcta gatctgttcc actaaaagcg gaataatgcc gtttgtctat
    65101 ccaataaaca ttttcctctt gctcatagtc ttggtataaa ctttttaaag agccgtacaa
    65161 ttcccgtcca cccgttccta tcacattatg cggaggaaat aagcggttct ccggatgaaa
    65221 ggaatctttt ggatcatgcg catcaatggc aaaaacgaca aaatcctttt gatcaataaa
    65281 cttctttgta tgagcagtca gctttttttc aattacttgt cctgctgtcc cagtagtcag
    65341 ctttccatcc tctgcaacaa aatcatatgt gtagtcaatc gagatcaatg cgttcatctt
    65401 agtcctcctt atacgagatg tttgacaaat tcgatcacca tttctgctga tcgtttgcct
    65461 gcgtcttcga taaattcgtc aaagctttgt gtcgccgagt gatctgctgt gtcgctcatt
    65521 gcacgtacga tcaaaaatgg gatattgaac tgacgagctg tttgtccaac agcggctcct
    65581 tccatttcgc aagctaatgc ttcagggaaa ttcgttaaga tttctttgat tttatctggc
    65641 gagtcgacaa atgtatcacc tgtaacgatc aatccttctt ttgcgttcaa attcgttgct
    65701 tttgctgctt taaccatttc actgcgcaaa tatgtgcttg cttcataata tagaggcatt
    65761 cctggtaatt gtcctgggtt gtagccaaat cctgttgcat ctgcatcaaa ataagctact
    65821 ttgtctgata taacgatgtc acctacttgt aagccttcac cgattccgcc agctgaacct
    65881 gtattgatca ccatgttcac gccgtattgt tggatcaaca gacttgtggt aatagatgct
    65941 aagacttttc ctataccgga acgtacgacg atcacttcgt ggttacctaa tgaacctgaa
    66001 ataaataaag cgcctgcgcg ttcccatgat aatggttcgc ttaggttctc tctcaaaatt
    66061 tttacttctt cttccattgc gccgataata ccgattttca tctttttaat tccttctttc
    66121 tatataaatg cgattgctaa aaaaaccaca cataacatta ggataacaat aataagagat
    66181 ttcatcaaaa aagagttcca tttggtcgtc ttttcccgtt cgctgatcct tgttttcgtg
    66241 attggtttat tctttttgct ttctttacga taaaagctgg caatcttttt ttcttcttgc
    66301 tgataagctg tttctgcttt tcgctgtttt tttaatgact cgcttgcttg tgcttgttgt
    66361 cgcttgcgaa gttcgcttcg cgtaataagc ggtcctttgg ccataagccg atccctctac
    66421 tttcctttgg tcaatagttc ccagtattga atcgcataaa tcgtctttgc atcacaaatc
    66481 aactgatctt tcatcgcttg ttgcgcctct tcaagagtta gatgatacaa ctccagtact
    66541 tcgtcttcat cttgtgctaa aggattctcg accttctcta ccccttgtgc atgataaata
    66601 tgaaggactt catttgcaaa acctggtgaa agatacatcg aagtaagatg gctcagcgac
    66661 ttcgcacgat agccagtttc ttcttctaat tctctagctg ctgtcatttc gggattttgt
    66721 ccttctcctg gatcgatttt tccagctgga atctccaaaa tcactttttc taaaggtttt
    66781 cgaaattgtt tgacaagaag cagacgatct tgttcgtcaa aagcaatgat cccgacaccg
    66841 ccaggatgaa ataccagttc tctcttcgaa gttcctccat ctggcaaacg aacttcgtct
    66901 acagcaacat caataatttt tccgctatag atttctttgc gactgattgt tttttcttca
    66961 aattgctcat tgttcagcat atcttctcct gctttctttg taatcataac tgcttttttt
    67021 tcatttttca atttttctca aaaactcctt attagtttac catagataaa ccttagattt
    67081 tctctaaata tagaaaatcc ttctttagtc cgatactctt tatagtagtc cgtatgctaa
    67141 aataagtatg taatcgaata acgaaaagaa ttcaatactc aacgataaat gacatggagg
    67201 gtttattatg ataaaacgaa attggccgtg gcttctagca ttggtcttgc tatttctctt
    67261 tgtccgaaac aatagttttt cttttgttct aggactttta ttgataggtg tagttttagt
    67321 tttgtgggga ctctttggtt cgcgcaggaa aaagggaaaa caagaagaaa ttcctgcact
    67381 gactgacgaa cttgaaactc actatgaaaa aagcggtatg acagcgaatg aaatttcatt
    67441 ttttcgacaa acaatgaatc aaacaaaaaa tgagatcaat caattgcaaa tgaatatgca
    67501 gcagacagcc aaacttaaag caatcgatct ccgccatgat ccagtcaaag cagcgaaagc
    67561 tttattcaaa gaattggtga aagaaccaaa ccgactgcat gaagcaagtc agtttcttta
    67621 tacgcatctg ccgaatctag ttgatttgac aaataagtat aatgagatca atgaccatga
    67681 gatcaaaaac aaacagacct atgaaaaact agaagaaagc gcgcagatca tcgaccagct
    67741 gtcagcttta atcgcacaag attatcaaaa attcgttgct gaggatctag atgatatcga
    67801 cgtagagata tctgttgcga aacagagctt aaagcgtgat aataaatatg aaccagaaca
    67861 aaaggattaa ctcttttgtt cataaaagaa gactcggaac attcagatga tgtctggctg
    67921 tttcgagtac tttttctaaa gtagagacat tcatgtaaga atcgagaaca gattcaacaa
    67981 ggaggaattt tttatggatc ataaaccgac tgaaacaaaa gatgttacac cagttaacga
    68041 tacacttgaa gatttattga acaacccgtt ttcaactcca acagatacgc tgaccacttc
    68101 acaacaagcg gagattgatc agctccaaga gcaacagaca gctgctcgtt taattgacaa
    68161 actaccggcg gaacgccaag aacaagctaa acagctagca gcaaaaatcg atgctaatga
    68221 tgcacagtct gtcatcagct acggatcggc tgcccaagca aaattaagtg aattctcaca
    68281 atcgatgttg aatcatgtgc aagcacaaga tattggtcct gtaggagatt ccttaactga
    68341 actgatgtat cgtctccaag aagccaatcc tgacgaactg cgtgccggag aagggaacat
    68401 cttccagcgt gtcttcggga aggtcaaaca atcgatctat gaagtgacag caaaatatca
    68461 aaagattggt gcacaaattg acaagatttc agtgaaatta gataaagaaa aagacggtct
    68521 gctaaaagat aatctgatgt tagaacagct ttaccagaaa aacaaagact actttgatgc
    68581 actgaatatt tatatcgctg ctggagaatt gaaaatggaa gaacttcaaa caacgatcat
    68641 tccagaagcg atgaaaagag cagaagaaac tggcgatcag atggatgttc agattgccaa
    68701 tgattacacg caattcctag atcgtctgga taaacgtacg catgatcttc gcttagctag
    68761 acagatcacg atccagcaag caccacaaat ccgtttgatc caaaacacaa atcaggcctt
    68821 ggctgaaaag atccaagcat ctatcgctac agccattccg ctgtggaaaa accaagtcgt
    68881 gatcgcattg accttgcttc gtcaaaaaga tgcagtaact gctcaacgcc aagtctctga
    68941 aacaacaaac gacttattga agaaaaattc agaaatgctg aaaatctcag ccatcgaaac
    69001 agcgaaagaa aatgaacgtg gaatcgtgga tatcgagacc cttcaaacca ctcaaaatga
    69061 tttgatcgaa acaatccaag agacattgcg tatccaaaaa gaaggaaaag aaaaacgtcg
    69121 tcatgcagaa gtagagcttg gacacatgga agaagatctg aaacaaaaac tgttggattt
    69181 aacccaatag atcacctttc gcttgttact aaaacaaacg cccaacaaca gtttattaca
    69241 actgttgatg ggcgtttttc ttatctttct tctaacttct ccattggagt ctatttctca
    69301 ttcatcttgc tgtgtccata gccatagcca aaataaatga tcagtccaat aaccattacg
    69361 ataccgaaca cgatccatgt cacagtttgc agacgaagca tcaatacaat acaagtcaag
    69421 atggagacga ttggcaatag cggaacgaat ggcactttga attctccagc ttttggtttg
    69481 ccaaacattt ttctcaactt cagtaagcct agactaacaa gcatcaaata ggcgagcgcc
    69541 atgatattcg ttagttccgc taatacattc aatgggaaaa atccggcaaa gaatacagct
    69601 gccacaccag cggcataagt cgcttttttc ggtgtacgat gcttttgatc gatttctgtc
    69661 ataaacttag gaagtaagcc atccttgctg acagcaaaca gtaaacgagc aagtgaatac
    69721 atcatcgaga tcgttaccgt cagtagcgtt aaaattgccc ctacagcgat caccgcgccc
    69781 actgttccat gtcctacata cctcattgca aaagccactg ggtcattgac tcctagttca
    69841 gtatacggaa cgattcctgt caagatcagc gtcacgatga tgtaaaggac agtagcaatc
    69901 agtatcgaac caatgattcc tcttggcaca tctttttgcg ggtttttgac ttcctcggct
    69961 gccattgcaa cggcatcaaa tcccaagaaa gcaaaaaaca caagagctgc accatctagc
    70021 acaccggaaa aaccaaaagg catgaatggc tgccagttat caggtttaac gaaaaatatt
    70081 cctacaatga taaacaacgc gatgatacca aatttgacat ataccatggc attattcaaa
    70141 cgtaatgctt tcttggcttc aagcgacacg atgtaagtga cgaatatcac tacgagcacc
    70201 gcaatcaagt caatgtatgt accattttcc ggattgtacc cgccagttaa tgcttgtgga
    70261 agttcggccc ctaaactttt caaaaaacct tgcatatagc cagaccatcc ggaagcaaca
    70321 gaggaaaccg ctagtaaaaa ttccccgatc aacaaccacc ctgtcagcca ggcagcaaat
    70381 tcaccaaata caacatacag ataggcatat ggcccaccaa tcactggcac tcgcgaagca
    70441 aattctgcga aacttagtcc agacaaaatg acaacgattg cagctaagac aaatgaaagt
    70501 gacagtgctg gaccagcatt ttgattggcc gcaacccctg tcaccacaaa tattcccgta
    70561 ccgatgatcg caccaattcc aagcatgatc aaatcagacg tttttagttc ttttttcatc
    70621 tcactcgtat gattgagatt gatctctttc ttacgaaaca aatccattga agttcctccc
    70681 cattttaggt tggaaaacag cgattaaact gttttcatat accctaaaag gataccacct
    70741 aaaatgacta aaaggcaacc aacaataaca taaatgagct cttttttcgt ttttctttcg
    70801 ccaaggatga aaatcccacc taaagtagag ataatgatcc ccatttgtga aagtgagaag
    70861 ccaacagcta aaccaagtga tttgactgtt agaagcatgc agatgtttcc taagccccat
    70921 aataatccac agatcatgtt tttccacaca aactgatcga ctttaacttt acggaaagca
    70981 aagaagcttg cgcctaagat cattccgata ctttgaggta agataattga catcgcatcc
    71041 aaattcgccc agttgacgat gatggtatat acaccataac caatcgtaga gaagatcaat
    71101 gctctaaaac ccttaccaaa atcaagcatt ttattatctg tatctatttt tccttcgtca
    71161 tcttgtcggg cagtcaaata cgcaccgctt acaagaagag ctaaagcaat aataccgtat
    71221 acataatctt tcgtttgtgt ccattcatgg aagaaaacgg ctcccgcaat cgtattcaaa
    71281 attaattgaa aaccagtaga caatggtagc cctacagaaa cacccatgta cttcattcca
    71341 tggaactgtc cattttgtcc aacactccaa gctaagccgg ataaaaatcc gatcaagaaa
    71401 atccaagggg tgattacagg actaacaacg aaaaagacaa ctaaagaaaa cagaaatgca
    71461 ccgatcgtca ttcctagtgt ttgttgattg gcatcgccac caattttacc acttactaaa
    71521 ccaatactac cccatgccaa catagggact aatgctatta aaatttccat aaccaatctc
    71581 cttttatttc acatgataag aaacttatca gcgaaaacgt taacaacaca agcacttttt
    71641 ttcgtttcta acgattttct aacgtttttc attataaaaa tttaagattg ggaaaaataa
    71701 agtcattgtt gtcccttttc cttcagttga ttcagccgtc aaatggatac ctaatttttc
    71761 ggccagattt tttgctaaat aaagtcctaa tcctgttgaa tgtgttttgc taagtcgacc
    71821 atttctccca gtaaatccct tatcaaagat ccgtttcaag tcttccgctg ggataccgat
    71881 ccctgaatct ttaactgaaa ggctgactcc ttgcgcttcc ttttctatgc tcacaatgat
    71941 gtttccgtga tccggcgtat atttgatggc attactaagc aattggttga agataaaagc
    72001 gatccattta gcatcggtca aaacagtatg atcctcacca acgatctcgt agcgaatatt
    72061 tttttggata aaataatttg cctgactgcg tatcacaggc tgaatgattc cttttagtcc
    72121 atattcttgg atgaggtagt cccgcgagaa actgtcgagt cttgcataat acaaaacttg
    72181 ttctacgtat tcatcgattt ttgataattc attttctagt aatgtatact tttgatcgtc
    72241 aatatcgaac tcgatcgaac gaactagcaa tttagaagcg gaaagtggca ctttgatttc
    72301 atggacccat gagtcaatat aatctttttg gtcttgttga ttactgattg ctgattgcat
    72361 tacttcttgg tgttcacgga tcagctgatt gatatattct tctaccagtt tttcttcttc
    72421 tgtcctccca ccactcaaat aattttgcaa aggggaagtt ttttgtatgt cggctaattt
    72481 tccccaccat cttctcttgc tcaagtaacc acccagcaga taaaaaatca gaaagacgcc
    72541 ctcaatcaaa gctaaataag caattgtgct caaatcaact ttgatgtttg gcgccagcca
    72601 catcacaaag atcgtcaatg caataaaaaa cagccatccc aagatcaatg tccactgatc
    72661 tttcaaatat ttaaaaaaat tcatcttaac cgctcatcct ttcagggaac gatatatccc
    72721 tgtcctactt ttgtttcgat atatccttgg atacctgcct gttcgatttt tcggcgtaac
    72781 cgattgatgt tgactgtcaa tgtattgtca tctacaaatc gttcgtcatc ccacagtgct
    72841 cgcagcaatt tttcccgact taagatcttt ccattgtgct tcatcaaaat aaataataga
    72901 cgatattcat ttttgctcaa atcaatgatc tctccgttga tttccatact tccgttgtca
    72961 acattcaacg taatgccatt gtggctcatc atttcactag ataattctgt gtagttgtaa
    73021 gaacggcgaa gtaatgcatt gatttttgca atcagtacat cgatttggaa atgttttgtc
    73081 acaaaatcat ctgcccccat gttcatagcc atgatcatat ccatattcgt attcctgctg
    73141 gagataaaaa tgatcggtac tttcgatact tcacgtattt tttgacacca ataatagcca
    73201 tccaaaacgg gaagattaat atctagtaat acaagctgtg gttcttctct ttcaaagtct
    73261 gagaacactt gattgaaatc ggtcgttcca aaggtttcaa attgccattt ctcaagttcc
    73321 tccatgatca attgtcgaat gatctcttcg tcttcgacta ccatgatttt tgccataaaa
    73381 aatccctcca tctttcttct tgctactaca atatcaaaga agcccttgtg aaacaagttg
    73441 gcttacctgg aaaatgtcat tttagcaaac gttaaaaaaa actggaaata tgcgatttaa
    73501 tcgcgtttgt ctcttccaag cagcttaaat ttattatgtt attcttaata attggtctat
    73561 tatctgttat ttttctttcg ttgtttttgt cttttaaatt ttcgataaca ccaataaccg
    73621 aaaagcgtta gcactagcaa tatacctaga aggagtataa gtaatcgata aagatggtat
    73681 ttttttgtct gttctatctt tgaagagact tcttctgtaa agggaactcg tcttcctgtc
    73741 actagtaatc ggtgagtgtt cacggtgtaa ggtgtacaag tgataagtgt gactagatcc
    73801 tgcttttctc taattgctaa tgtatttgtt tttgttggaa ggacaacaat tttctcaacg
    73861 acttcataag cgagcatccg accatacact tcaagataga atcggtcatc ttgctccatt
    73921 tcttcaagat ccgtaaagag ttttttctca gcaataccgc tatgggcggt aatcacggaa
    73981 tgtgtactct ctcctccagt tggaaaagag gtgccttgca ggactgtcgc tcctctatct
    74041 aacaaaagat cattcgtttc atcaaataaa ggcaagctaa cattgatttt cggaatatag
    74101 atggctccga tcatatgttg ttcgtaatat tcttttcctg gattttggac atttctaacc
    74161 gcttgctcaa aaggatcttt gacttgtccc attcctggga ttactgatgt atgagcaagc
    74221 gtctgatttt tcttttcatg cactgctaat tgttgctcat gtttttcttc tttatcgcgt
    74281 tcaagctgct tttgataatt ctcgatcctt ctttgatcca aataattgct gagagcatct
    74341 gctaaaaatg gatatgtaaa aactgcagct ccggcaagaa acatcactgc cataaataat
    74401 tgtaataaaa gactgatttg ggtttgaggt ctattaccta ttttcttttt cattttcttc
    74461 accttcttat ttaaaaaaac tgcagcaacc tttataaaac cgattgctgc agcttatttt
    74521 tgttgcttat acttcagact tcattttaga tttacggtac cagctgtacg ctccaatcat
    74581 caaacttatt ccgattagta agaatgccaa gagcccgttc ccaccagtag caggaagtga
    74641 cccgcgtttc atattcggta ctctttctgg ccctggattt tctactccta cgatctgaat
    74701 ttcttcatta tagcttccat aagagatgat aaattcagta aaggctgcct cacctgttgg
    74761 aagtacataa ccttctggcg ccatggtctc tttcatttga taggttccat aatctaaccc
    74821 ttgaacctca aagtatccat ttccatctgc gacaaattct gttgcttgtc cgcttgttgc
    74881 ccactcaatt ctatctgctc ctgattcata aacagctaaa ggcgactccc ctttataaaa
    74941 tattgcgtat tcagaacggt cttcattcca caattcgaat cttgcatctt taagcaattc
    75001 actgcttgat gcatcatatt tttcaaactt tcttccacct gttgtgactt tctctggcgg
    75061 ctctactcct tcttcataat caaattcatc atttcgtccg atttcaataa ccgctgtgtt
    75121 gttatggaaa tcatccgctt ctagttctgt ggaaaccttc aaattatacg tgatcgttaa
    75181 atctcctcca cgtgcatctg ctaatctacc taaagtatct actttggcta ctccattttc
    75241 ttctgtcaaa atcgtcacga caaacccgtt gcttactact tctactatat aatcttgtcc
    75301 ttttgttaaa atcgtctcgc cggctcgcac ttctatttcc tgatcataat aagttagacc
    75361 aactgtaggc gtatctgtga ttttgtaatt tttgataaca gcgcttccgt tttcaaggac
    75421 agaatcgatg aaataaggaa taggtgctgt gatcgtgtaa gaagccgttt ttcctctttc
    75481 tagatcaata taagaaatcg tttcttgttc tccagcttca ttaataatcg ttacttgtct
    75541 aaggtcgctt tcctctacat tcatctgttt atctgcttct ctgatttcgt ttttcggata
    75601 caaatgcaca tctgtattgt atgtgtcttt ccatgtagaa ccatcccaca cgccatccac
    75661 catatcaggc atcatcactg gcatcataac aaccattgga gacgcgattc tggaaatatg
    75721 agctggcgaa taagtttcta agaaaagata gactttatct ctagaagaag gtgcttcttc
    75781 cgtcacttgg acggtagaga ataccgcttc tccagcttca ttcgttgttt gtttgtcaat
    75841 acttgtcagt cgatatttta aaaaccaact ttctgtgtgc cgtttttgaa tccattcaat
    75901 cgcttcggca gaattaagac cgtcttctcg ttccggtgtt aaaggattat ctcgaatcaa
    75961 atcgtaatat acttccgtta cgtcaaacaa atcaaaatcg actcctggaa tattttcttc
    76021 accaaaatcc gtagaaacca atccgctatt cggtcgttct tccggaacag atgagaaacc
    76081 ttttttgtgt aatgtaatcg tcacttcact tggtttttgt gcgacttctt cggctttgac
    76141 tagttttccg ttcccgaaaa tccctattcc cgcagtaacg agtaacagta cactcattcc
    76201 cgtgacaatc atttttttat tcattttttt ctccccgttc tttttttatt aataaaacag
    76261 cacctaacaa taaaagaatt cctagtaaag aaatcaacgt tcttgcttca ttcgtttgcg
    76321 ggaatacgga ccattttcct gattgacctg gattgcttgg accactcggc tctttcggtt
    76381 tgtccgttgt ttcttttacg gtctcgttat aaacacgtgg tgttgcggat tcataggcag
    76441 agactggaac tttcccggat tctaattcag ccatctcctg tccgttaact actacatatt
    76501 gtggttggcc ttttgcatcc acccaaaatt cagggatgat gacctcgatt ctcttacttg
    76561 cttcatccat ctcgtaacct tccacacctt ttaattcttc aaaataatag gtgccagaag
    76621 gcaagaaacg ttgtcctgtc gtaacaaggc cctctttatc cgaaatgaat ttgcttacat
    76681 ttttgtcatt caaaggatca ttgtctgctg gtttgatcca ttgatttttc aagtcattag
    76741 caggagccat atctaaataa tatttccccc cttctatcat ctgatataga gcaaaaacag
    76801 caccttctaa tggttttcct ttttcagttg ttcctctttg acgtccatac ttgaagaagt
    76861 atggatctct tagataaccg acatttttag gatagatatg aatctcttgc agttcctcgg
    76921 ttgattctgt cgggtgataa attggcaaaa tagcagcaat tgggatagct gtctgatcga
    76981 tatcaacatc caatccaact tctggatcaa tcgattcttc gaaaatcaaa taaactgcat
    77041 cccgatcttg gtttttctta ggtgctttga tacgtgcaat cccgtctcct aatccgccaa
    77101 ccgtatcttt cccagttgtt accgaagtcc ctatttggac aagcctttct tctgtgatta
    77161 gctgacggat attgtttctg ttcgtttcag cgatttgctg gacgaattct ttaggagtca
    77221 tgttttcagc agcttttttt tcatgataat aatcggtcat gtcgtaaatg gcaaatgtcg
    77281 ctccatttag tggcaccgtc tgtgaaatga tatctgctgt ttcccctgct tcctcagaga
    77341 tagccaagcc atcattttca tggtattcaa attgatcgtt ataatcgata tctcgaatca
    77401 tccgtttatg caacacgaat tccacgacat cttcccctga ttcttctgcc gacatcgcat
    77461 gtggaagaag gactgctgca agcggtagta aaacaagtaa ttgaagcatc aaacacaaca
    77521 gctttttcat taccttgctc cctccttttt agattgtctg acaaacaaac cataggctgc
    77581 tcctgcaagc gccatgaaga atgcagcaag caggatatag aataatcgtc cggatcctcc
    77641 tgtagcaggc aacggatttt caggatcgtt cccgacacta agctgtaatc tgattcgatt
    77701 tgtctccaaa agttcatatt ctaactcttg ctgtagatca ggcgtctctg cttcttcgtt
    77761 tggataatac gaaatctcaa cttttagtgt acccgcttct tttcctggaa ctacccgatc
    77821 attttctatg tcaggttctt ctcgataact aatttctaaa ataaagtaac ctggaagttt
    77881 tctatagctg tcaggtgact tcacttcctt gatccgatag accccttcca acaagtctga
    77941 agcattgaat agggaagaat cgtttggatc tggtgccaag cctccctcga tgatttcata
    78001 ctctcctgca ctattttgtt tctcaattga aaattctgcg ccttcaagac gtcggctatt
    78061 catactgtca attttcaaaa gttccaaatc gattggcgct agttcatctt ctaaggttac
    78121 ttgtagtaca ccatcgatga tttcatagcc ttccggcaag ggagcagttt cgtcttcgat
    78181 gaccgtatct tcaatgataa acttaccttc ttcattcagt gcaaactgga acacttgatc
    78241 agatagccga tacccatttg gtgcgacaga ttccgagacc tcatattcac caatagacag
    78301 atgcagaggt tggtcgtaat ttaaatcgac atacttttct actcctacgg cacgagaata
    78361 gaagtatccg atcccaggca aacgtttcga ttcttctggt tctaacggat taccagtgta
    78421 tgctcgatac agcgggaagg aagaatcccc cactttcctg atatcgaaac ctgcaccatc
    78481 taatgtatgg ccttcatggt ctaattttct aactcggatc tcccgataat caaacgtatt
    78541 gtaagcagtg aatgctaccc ataaacgatc ctcttcatct gttgtatacg tgagatattg
    78601 ccaattttct tcacctgttt gcttgagttg gatagtccct atagcattat cgtaaagtcg
    78661 caagatccat gtgtcatttt catcaggttc tttgaaacct tctgggttct ggctctcaat
    78721 gattttgtat tctgcatagt tggtagtttc ttcactatcc ttataaacaa atgaatctgg
    78781 ctctccgatt ggatgaataa ctttctcacc atccacgatt acatatttcc cgtcttcatc
    78841 tactgaatag aacgtgagtc tccctttctc ttcctctact tcgttcacac cagaaagccc
    78901 tttcgctact ggatatccga tttccagtcc gttaccatct gtttcataaa gttcaaactc
    78961 tgcgccattg attggcatat tactgccttc aattagttta ttgatattca tgtggattgg
    79021 cttgaattca tttcgcattt ccagtttgac atacaactca tcatactctg tgccttctat
    79081 gttaggctct tgtacaacag aaagcttgtg atattctcct tcataatagg aattcggatc
    79141 tttaccttcc ggtccgccga ctctcgaacc agatgtatat tcatctacaa gctcgtagtg
    79201 acctaacatc tcatcttcgt tggctgcata ttttttgatt tggaattgat acgtctcatc
    79261 tactaactga taacgtggtg gtccagcgat ctctctgatc caaaatatgt cgctgactgc
    79321 tccagtttca tctcctaaaa tcggcatctt cgtttcaaag atcgctattc cgtccgtggt
    79381 agttttactt gtttcgattg gttcggcttc cccactctct ggattttggt catataatgc
    79441 aaattcgact ccagccaacg gctcgccatt ttgacccttc ttgctgactt ggaaattacg
    79501 gcctttatgt tcgtaacgaa tggaagaaga tgggaaatac atccgtccag tagtgatatc
    79561 attctcataa tcctccaggt tctgaatata ggccatattg ttcactgtgc aaaaatttcc
    79621 gtcttgagct cccgcatcaa gttttacttg gtacttgatc ctgaccattt ccccttcacc
    79681 taaagaaatc ggagaaaatt tataagcttg gttttcccgt ccgacatacg ttgtcggagt
    79741 cgccactact tctggtgggg cttgtccatg acgttcttca tcccatattt ctggctcttg
    79801 gtacttcatg ccgttttctc ctggatctag atggtaaaac tgaatatctg ccgatctgcc
    79861 agctccaaat ggtgagacat taaaaccagt ttcatcataa agtgtggctt gctggatcgt
    79921 tctcttgaag gtagaagaga tatcctccaa ggctgtaaca atgtcattct tgttgttcgc
    79981 attgtaatat cgcggtgtta cgccatcttc ttctaaatca gcaatatttt tcaatacatt
    80041 tcgtccaata gcatctagtc gttgtctccc gctaacgttt ccatcgattc ctaaaccaat
    80101 ggagaagata cttggcgggt tctcttgata cttgtttttc agccaatgat gataagcaac
    80161 tgtgttgatc gcagatgact tttcttgcga agtaggactg ccattcgtat tgttattaga
    80221 agaaccatca ccaacccagt gagtcgcttt attatctcct tcttttacct ctccataacg
    80281 atagtgtaca tttacttcat cttctggacg gttaaagtca gatgcatagg taactggatg
    80341 agtaaaccct gcattagaag tattcccaga aaactcctca aaatttctga acaaaacgtc
    80401 attatcttca gcaatcttat cttccatcac agtccagttg ctccaagctc cattagtgct
    80461 cgtacgataa cttgactgaa tcggtgcata actgaaggtc ggtgtcccat ctcccacaac
    80521 gattaggatt ttttctggat ttctattttc tccgccattg tctttataca atgtttcata
    80581 gccattttta agccctagtg taagcggagt tcctccgatt ggtgtacgat ttaatgctgt
    80641 attctcactt cccgtcaaac gattgatatc atttgtcaat ggaaagatgt ccgaactgat
    80701 ttgctcatgg ttattgatag ctgtactatt atggtaaaaa ttcaccatac cgattcgaat
    80761 atccagactc gggtcagaga gcagatcttt actcatttcg tttactgcct caatcaacgc
    80821 agcattttta gtttgactat tggtcccagc ggttaattca ctcatactcg ctgacttatc
    80881 tagaacaaaa acgatatcga ttggactgat ttcctttttc tcgcccccga tgacatctag
    80941 atagacattg taaagggttg ttgcatcttc aggatgtaga tcagatgctg tgctgcttgg
    81001 cagaacaggt tctacccatt ttttgatgta cgccccgtta taatccaagt aactgttttc
    81061 aaaattccgt tcatttcccc aaagctgaac ggtttgagct ggaacgtttc tatcttcttc
    81121 gcctgcagtt gatccattat tagtagcata gtcgtaattt cgccagttcg ctcccccgtt
    81181 tgtataatca ctatcatcga tcaagttctc tccgtcatat ggcgagcctt tgtctccttg
    81241 atagcgttca ttgctttgtg tccaatttcc taacactttt gtatagtcat tcgttgtaaa
    81301 cttcatctat tctttcatca accaccactt gaagaggtag ttacccttcg ttcacatcgg
    81361 ggatcttttc tgtttcaaaa atcaatgtgc cggtttctgc ttcttttgaa taaacttttc
    81421 cgacatacca ttcttgacca tcgatcgtct cgacttttag gtcttctcca tcttcatcat
    81481 aggaggatag acctgttcca cgaacgtttt ttacggtacc aatcccggcg gctgccgcat
    81541 cgattgctaa acgtattcta ccttcattgg cactttcctt tttttcaaaa gccagatgcc
    81601 attcaagggt ttcttctttt tcaatatact tcccttcaat ttttgcatag tcctcatcta
    81661 agaatacctc atcctccttt gtttctgttg actcagcagc tacatccagg gtcgtcatat
    81721 gatagactga ctggaaatat ggtccaaata gcaaactgac agttactaac tgcaaaagct
    81781 tcaattttaa ccctttcaca tccttatact cctttcaaaa atatttgtct tctttcacaa
    81841 caatcaacaa aacaatgccc atctaattat aatttaattt aattttaatt ttaaatcaaa
    81901 tgatatcctt tttagttaaa aacaccaatt atacaacatt tattattaaa attaaattat
    81961 aaaattttat aacgttctca tttaacaaaa cttaagttat taagacaaat gaataaacaa
    82021 ctacgctttc ctcgaaacaa aaaaataaag cacaaatgcg catttacgca ctcatgcttt
    82081 attcgtacaa ttaattcaga taacggcagc gcataggatg ccaataacac ttcctaaaat
    82141 agctcctcct aaaatgtcag taggataatg taaaagtaaa aaaatcctcg aataagcgat
    82201 caaacaagca aataaaaagg ctaatattcc tgcaactgga cttaattcga acaacgcagc
    82261 tactgataaa aaggctagcg ctgtatgtcc tgaaggaaaa gaagaagtct tcggtttact
    82321 tgtgtaaagg acaagccgac gatttttttc ataaggtctt ttccgtcttg tcgttttttt
    82381 gataaaaagc aaaccaacaa aaaaatagat caaactgccg ataagaatgg ctagaccata
    82441 ttctctagta tcaggtatca agactaaaac agcagcaagg agcaaccaaa taaaaccacc
    82501 attagagata ttactgataa atttcaaaaa attgattttt cgactatccg ttttccgttg
    82561 cttggcgaac ttgttgataa tactatcatc gattttagca atcaaacgca acatgttatt
    82621 cctccttttt aagaaccttt tcttgcgtac gatggataaa aagcaggact tgaaaataaa
    82681 acaagaaact gaaacctaat aaagcaaaat agattggtcc tgcaaaccag aatgcgacaa
    82741 gaaggatcaa cgtgcctgcc aaatagaaaa gcgcgctttt gaaatcatta aaaaacaaga
    82801 aaaatgcagt aatccaagaa gcttcttttt gttccagttg aagcaagatt ttgtaactaa
    82861 agagaagcgc gcttaataga agcaaaaaca acgtagtata catcaatgta tagccaattc
    82921 ccccacccca atagcggaaa atctgataat cgatcaatag aagaagaaaa taaacacttg
    82981 ctaaactatc ttgctttcca taaagagaga agttctcacg aaactttttc cagaatagtg
    83041 aaccgagctt tttctcttca ttttttttgt aatgataaat catatacaga actgttcgac
    83101 ttgcagttcc taatgtgaaa acaggcaaga cgcacaggaa ccatagtagc tgtaaatgga
    83161 taagacgtgg aatccattca atgatttcta agaaataatc attggctttt ttaccaatcg
    83221 atcgattcat catccttttg aacctcctgt caaatccatc ccttcaatga aataacgttg
    83281 tgcaaaaaag aacagcaaaa tcgtcgggat caagacaagt gttgctcctg ccatcagata
    83341 attccattgt gtcgttgctt ggttctgaaa aacttgcaag ccaatctgta acgtgtattt
    83401 ttcttgatct tggatatata acagaggacc taagaaatca ttccaagctg cgttgaagga
    83461 attgatcgca atggtaatca aggcaggttt cgtcaatgga agcatcaaat gactccaaat
    83521 atacaaatga ttcgctccgt cgatttcagc agcttcgatc aattcattat tgatcgataa
    83581 gtaaaattga cgcatcagaa atatattgaa cgcattgccg aagaacgatg gaacgatcag
    83641 gggcaaataa gtacctaccc agccgatctt ggagaataat acatattgag ggatcatcgt
    83701 tacaaacccc gggatcatca tcgtagaaag aaccaaagca aacatcagct ttttcccagg
    83761 aaaatcaagc ttcgcaaatc cataagcaat aaaagaattt gaaaggacat taccgatcac
    83821 tactagcaca gtgatgaata atgtatttct tgcatagcgc caaaaaggaa aggcggcaat
    83881 cgtatccaga tagttttccc atacgatttt ttctgggaaa aaggtcggag gataacgaac
    83941 gatttcttcc attggtttca atgaagtaaa caccatccaa agcaatggaa tgatcaaaat
    84001 gattcctatt actgtcatga ggacataact tagtattttt tttgtttgcc gattcacact
    84061 ggtctttttg aaataatcca tcatttgccg tcacctccag aataatagac ccacttaggt
    84121 gcaagcttca aattgacaaa cgtcagaacc aacacgatca gaaacaggat cattgacata
    84181 gccatcgcat aacccatatc aaaagctacg aacgccttgt tccacatatg cagattataa
    84241 aaaagcaaag aatttgcagg tccgcctgtt ccatttttcg tcatgacata agcttcttga
    84301 aaaatttgga aagaaccgat cgtagaggtg atcacatcgt aaaaaataat aggagtgatt
    84361 aatggcaaag taatactttt gaactttccc caaacgcctg ctccatcgat ttctgctgat
    84421 tcatataaag atctaggaac attttgtaat gtagctaagt aaagtagcat tgctcctcca
    84481 gaactccata ttttcatcaa aatcaacgca ggtttcgtcc attgtggatc aaacagccaa
    84541 gctggtccag ggatatggaa ccagcccaga aatgtgttga tcaatcctgc agatggagaa
    84601 agcagctgca tccataagat gtagactgct actcctgata agactgccgg taaatagaaa
    84661 gctgtacgga atacactgat tcctttgatt ttttgattga gtactgtggc taaaaacaca
    84721 ctgaaaatcg tcgtcagcgg tacattgaag atgacgaaat aaacggtgtt gtataacgat
    84781 ttccaaaata aatcatcgtg aacgaacatt cttttgaaat ttgctagacc aatgaaattc
    84841 atcttggatg tcaaattata atcggtgaaa ctaccaataa ctgaaaaaag cataggccct
    84901 agcataaata ccaagaaccc gataataaaa ggcgagataa ataaataggc ccatcttgct
    84961 tcttttttct ttcggataga taaacgcttc aaattttctt gcctcctctg tacctagaca
    85021 gtcaaaaatg gattattgat tttgcttgac taagttttct actgcttttt gtgcatctgc
    85081 caatccttct tttggtgatt ttgttcctaa aagaatctgg tcaatctgtt cattcactaa
    85141 tgtcgtgtaa tccggagcat ctaaaggaac tggtgtgatc accgtatttt taaagttttc
    85201 gtccgccatt tgatagatca tttttccttt atccgttagg ttgtcattat tcactaaatt
    85261 ctcattggct gtcttgctcg ccatgatatc aaaacttttt tcgccgaatt tttcttgtac
    85321 ttctggagaa gaaagatatt tgatgaattc ataagaggcc tcaggatctt ttgctccgta
    85381 tggtacttcc aagacgaatc cgccacccca cgaccaatgg cctgaacctt cttctttttc
    85441 tgggagctgc atcacgccaa aatcaaaatc atccggtgca ttttccatca aactagagta
    85501 ataattgata ttttgggcac gcatggctac taatccggaa ataaatggat cagatacacc
    85561 agacccaaat tcggcttcta atttattgat cgtatttttc ccataataat cttgccagtc
    85621 ttggatccac tccaaggctt ccactttatt tttagtatca atcttgactt tttcatcttt
    85681 gtcaaaccaa ctagtcccgt tatctgcgtt tagcgcccat acatcagccc ctaaattcca
    85741 taatggataa aaaccgatgc gtgtaaattc ttttccttct tttttatcta gtttacgtgc
    85801 tgtttcttct aattcatccc aagttgtcgg tagatcttgt tcactgattc cagcttcttt
    85861 aaataacttt ttattataaa aaatgacttg tgtatctgta ttgaatggga tcgcataagg
    85921 atcaccttca tattctactg tatcccaaag ctgcggataa aaatccttag aagtgtcttt
    85981 ttctacatat ttggagagat tagttgcttg ctgtgcttct gctctttggg caacggaatt
    86041 tatgtcctgt acaataacat cgggtgcatt tccagctgtt attgcagata aagatttagt
    86101 ccagatgtca ccccatggct gatacttata atttacatgg atctcgtttt gtgattgatt
    86161 gaaatcctca atgatttctt cgatagcttc ttttcgtgca ccggatcccc aaaaggacca
    86221 gaaatcaata ttttttcttc catcacttgt tttttcagaa gaatttgctg cacttgaact
    86281 ggcatcgctt gcattacttg atccgcatcc tcctaataaa aacaatgctg aacttgccag
    86341 caaccctgta aacaataatt ttttcatatt ttacctccaa attttaatgt aaccgatgcc
    86401 ggttttaata taacgatatc attttgttct gaaaataaca atttataagg tatgattcta
    86461 aaaaaattat taatgatacc aatactttat ataattcgcg agcgctttct ttgaattttt
    86521 taatctttcg tagcagaatg agaatgtatt aaaaatagat taggaggaat tttgatgttt
    86581 agacaccaga aagaattgca gtttgaagca aaaccagatc gtccgaatcc attaatcgcg
    86641 aaatatctgc aggagctgat cggcggccaa tatggcgaga tgagtgtagc tatgcagtac
    86701 ctgttccaag gctggagctg ccgaggagaa gaaaaatata aagatatgct gatggacatt
    86761 gcaacagaag aaatcggcca cgtggaaatg ttggcgacaa tggttgctcg tttattagag
    86821 ggtgcgcctg ttgaagatca agaagcagcg atgcaaaaag atccaacaat cggtgccatt
    86881 atctctggaa tgaatccaca gcacgcgatc gtagctggct taggacctcg tcctgctgac
    86941 agcgtgggca atccatggag cggtgcctat atcattgcga gtggcaactt gttagcagac
    87001 tttagagcta atttaaatgc cgaatcacaa ggaagacttc aagtagcacg tatttacgaa
    87061 atgatcgatg atcgtggcgt aaaagatatg ctgtctgttc tccttgcaag agatagctat
    87121 catcaaaatc tatgggaatg tgcagtgaaa gaattagaag aaaaagaagg ttcaatctta
    87181 gtcccaagta ctttcccgcg tgacaaagaa cgaaaagaca ttgcttatga cttctataac
    87241 ttctcagagg gagaccaaag tagtgaaggt tcttgggcta gtggcaaagc actggatggc
    87301 gaaggcgaat atcaatggtt gaaagaacct aagatcgaag gcgctgcacc aaaattagaa
    87361 ccagtaacac caaaaatgta tgggacacct ccattcaaga aataaatatc tacccgtaga
    87421 aacacccgtt ttttgttcca cacgctttgt gagcaaaact gactaaagtc attaatcata
    87481 accacccttc aaaagggtgg ttttctctag agctataagc tcaaatcacc ggccagcgcc
    87541 taaagacgct ggctttcata ttttatgttc aagccatatt gcctttgcca gttttgccca
    87601 cctcttaaaa ggtttatgta ctactcctta gcccttaaaa ggatcgtctt actctcgtac
    87661 actcagctta tctaacgcac tatcatgttt ttcttgttct tgaatgtact ttttgatggt
    87721 cgcttcattt tgtcctactt ttgtcacata gtatccttcc acccaaaagt gtcgataccc
    87781 aaatttatat tttagatttg cacaatctct tgatgatctc ctgaatattg gctcgatatt
    87841 gattataaat tatttttctt ctatactttg gtgtgaatac aatgtggtat ttacacatct
    87901 actttgtacg ggctaaacta tttcccttta ttgctccacc cgcatagcaa gtggttttgt
    87961 atttcaatcg ctcggcgcgc tcaattaggt ctaaagacaa taaatctaaa aacccgctgc
    88021 ttcactgaca gaaacaacgg gttttcagaa aaaaatgaaa tgaaaaagat ctcttacggc
    88081 aatctatttt atttttttga ttttttataa atggaaaatg cttcaagaag tccaagaaat
    88141 aaagccgtat aaaaacaaga acctatgaaa tctttattta ttagatattc aacagaaatc
    88201 ccgataacac tagccaacaa tatatttatc agaagtgtaa aataaggatg ctttttatag
    88261 aatagaacta gtgttgtttt catagactct cctttcttca tatttccaat taatcacaaa
    88321 ttcacggcat tactagaaaa attaaagggg cgcagaagtg gaaaaatact cttcgacttt
    88381 ccctacaaac caggccatct tgtgtttaat aactatacca aatctaaggt acctctaaat
    88441 ctaaattcca tttgtggcgg tgacctccaa tttttaactc ttctatctcc catccagtat
    88501 acataacctt gatacttcga ccacttatat atcgaacaca caaataccta tccattgcag
    88561 gagtactacc taacttagtt gctacttgca tctaaataac agctgaaaag ataggactta
    88621 ctcttagtaa agtatctgaa ctattaattt ttaaactatc atttttatcc tcaactacat
    88681 gcacatctgt tgcaacttca ctttctgtct catccagata aatgattaag gaatcgggaa
    88741 ttgcaatatc ttcagctgac gctggaatag ttgagctaaa ttagtcatca tatctttatt
    88801 ataaaataac caacagcaaa aaatacaatg aaaaacaaac ttggaactaa tgtatcatta
    88861 ataaatgttg aaaaattcag caactcatta ctgtatgatt ttagcagccc aaccaacata
    88921 taccctataa aagctaataa gatggttagg aatcctttag aatttttact cattcataga
    88981 cacttcctta aataactttt attatagaag gtattgtaaa taataatatt gacaaaaagt
    89041 gactcaaaat aaaaaaaaac ttacattata ctggaatgaa ctgtattgat agtgtaccta
    89101 aaagctctac tgacataaga tcgtgtaatc ggtaaagtaa ttttattaat tatacgggat
    89161 gtaatcaatt agagaataaa ctaatcataa aaggtacttt tacattcata attgtcgctt
    89221 tgagattcta ctttggttca ctatctgacc caattgcaca ttttcgatca ttacaagtat
    89281 tggtgtcgtt agaacaacta aataaaaact agcggtagat ttttcagaat ctatgctaat
    89341 ttctgtatgg atgttccagt gatggcaaat ttctcttttc attgtttttc ttgtcgcatg
    89401 atatgccttt ttgtgttatt cagttaaact atagaaattc tttcctagac agatcttgat
    89461 cccaaatttt acgtttttga gcatcgatat agtttaaaat gacattactc atatctaaag
    89521 agtttagatt ttttaggact aaaactgtca gttgttcttt ttcttctttc tgttaaagta
    89581 ttgtcgcgac ttttcgtata cgttaagata tgtcgtgaaa aaacaagttt tgtgacacaa
    89641 aaaaacgaat gacttgagga aatcacctca atcattcgtt taaaatgcta tatattcttt
    89701 agtttaagat acggaaatta atgccatcga ccacactagt agaatgaacg acatttactt
    89761 ggcctttttt taatttcgtt atgtttagca tataaaaata ttatagagtt tacttacaat
    89821 gcttaaaaca tatactgtat aatctgatca attttagcca tgtcttgcaa tggtaagttt
    89881 tctatttttt tgagttttcg ttccttaaaa tcaagagatt ttaattgtgt aataattact
    89941 tgtcctttta tatctagctc ttcaggtaat gagtaacgtg tcggtaaatt ctttatagtg
    90001 gaagtaattg gacgtatgac cgaaaacatt gttttacggt taaattcata acgagagacg
    90061 actagtcctg gtcgtctttt ttgaatttct tttcctacgg agggatcaaa atcaatccat
    90121 acaatatcac cttttttagg aatataaatt ctttcttctg acactataaa atttctctcc
    90181 cttcaggagt taaatcttcc cattcgtctt tctcataata ctcggcctct tccccaccac
    90241 taaatggatc ttcaattttt ggaactaacg taattgttcc atcatcagaa tacacaacga
    90301 tatattcttg gttttctgaa ggtttctttc cgttatcaga aggtaaagtt accactacag
    90361 aacttccttg taatctagat tttgtaacaa gcattatcat cactccctta ataaaagtat
    90421 actatataac actaagtaac gcaaaattcc cctttgtaaa ctatctagaa aattgttttg
    90481 tttaaagtat atcttattgg atataaatag aaataaattg tagccagttc attttttctt
    90541 taaataaaaa aataatccaa gaaacattga acctatggat ccaaaagcta cccaaatact
    90601 atagctaact ccccgctacc ttcaatcttg cagataaaac gctttggaaa aaaatcgaga
    90661 aaatcgcaaa gacgacaggc catcctatca tgcctgatta taaacaaaaa gctggctatt
    90721 ccttttgctc tgacaaattt caattgggaa agttcacgaa actagcaggt gaagaagttt
    90781 caactgttcg gattaaagaa tgcccgattc aaatagaaac gttggttcaa cgaatttcaa
    90841 ctagagaaga ctttgctatt gtagaatgtg agatcgtagc tatttttgta gaagaaggga
    90901 ttttacatga tccaactcat atcaatgtgg ataaatggca acctcttatc tataaactca
    90961 gagaatatac aactgccaac cagtcgttaa gtttgaattt tagattccaa gaattcaaag
    91021 agtcataatg ataaacatca ttaggtataa ataaaaaaga ctcgcagaac gagtaaaaaa
    91081 caaatagaag ctatacctta gaaaggtcga ctgtgactct atagatgcag tatatgcagc
    91141 ttatgagcat ttcttctgtt ctctttgttt ttgggatctg tgctgaagtc tttttcgttt
    91201 tttgccgctc tttctttgaa aaatcgatta tgttatacct tctccattac taattcaggc
    91261 atctgttgag taatgatttt tcgcgcaaaa gaaacatctg ttacccaagg ttcgatttgt
    91321 tcttcagtca agacaagcgg cattcggtca tggattggtg cgactgtgcg gttaggttca
    91381 gtagtcatta tgattgattc tgccattttt tcatcctgat ggctacgata aaaaccgcca
    91441 atatacacta ttttttcctt atttgaaaac ataaatttgt ctttttcttc attccactca
    91501 taaaagccac tcattgggaa aacacaacga ttttgcaaaa atggttgatg aaaggtcttt
    91561 ttttcttcta ctgtctctgc acgggcatta atcatcaatt gtcctttttt aaatccggta
    91621 aatccccact tcatgatttc cggagtgagg atgttttctt cctcttttct taacgtcaca
    91681 acaagatttg acggaaaaac ttctccagct gctaattctg ctgcctgctc cggttgtttc
    91741 gtctgggctt ctcgataata attctgaagg agctctgact ctagatcaaa aaaataacga
    91801 ccacacatcc taatccctcc caatcttttt ttctatcata cactgcaaca agaagtccgt
    91861 accaacaaaa cgctttcaat ttgtgtagaa ctaaaaaagt tgtgacaagt gacaaactct
    91921 ccagtgaatg gtattctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
    91981 gagaagctgc tttttgaaat tgttccttgt gactcggagt gaaacggcag gcttacgacc
    92041 tctaggtaaa cggtgttcca gaagtagctt cttcgaaaaa taagccgaaa tttcacaaaa
    92101 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
    92161 aacctctaat tattaaagaa ccttttgcga agttaacaat ctttctttga tcaattgaaa
    92221 attttgtcta agtagtgata gatcctgtgt gactttcaac aataagatac ttccctggat
    92281 ttcagcaatc aacgctttgg cttgacggtc tgcttcttca tcggacagtt tttcttcaga
    92341 aagtgccagg atattttgtt tcgtatactt gatccattga ttgactaatt ctagtagcaa
    92401 cagacggtat tcttcatcca ctgtactcaa ctcaataatc aaattaccta caggacagcc
    92461 atgataagtg atctgtgtct catgatcagc aaaaatccag tccaacattt cttctaatgc
    92521 ttcttctggc tgttttccag catttaagat gtcttcgaac aattctgtct gccacacgac
    92581 catatgcgca tggatcaccg ctagacaaac ttcttttttt gaagaaaagt aataataaaa
    92641 ttgccctttc cccgtctcag aagctgctag aatatctcgg attgacgttt catgatagcc
    92701 ttttttataa ataagatctt tggtcgcttc caagatcttt tcctttgttt tcaatgatat
    92761 tctccttttt catttctcat agtcctatat tatacaataa attcatcatt ttttcttctt
    92821 aatcgtttaa aaaagactgt gccaaattat ctgacacagc cctcactata aaactgttct
    92881 catatagcta gatgttcatt gattcaagaa ctgcgaggac aaaagcaatt cctatcttat
    92941 gatagttgct ctaatacttc ctctgttgtc atcacttgat ctgcaataaa gccaaagttc
    93001 gtcaacgctg catccattgc ttcttgacca ggagcaccaa ttgcatctgt cgctaccaca
    93061 acattgaatc cactctctac caattcacgc atatgggaat cgctacacaa gtttccgttc
    93121 attccaccaa gaatcactgt gtcgattcca ttttttctca attggagcgc caaatcattg
    93181 ctttctggtc caaagatttt atgaggagag ctgataatcg tattttcatc caaatatggt
    93241 ttcaattctt cgatgaaatc agctcctgaa ccttcttcaa ctgattcata ttgacttttc
    93301 ctagcaaaca tctgttgctc aagcatcata tgttctcctg caccgccaaa ttgccattta
    93361 tggtcatgtg ggtaaaaata atgaggagaa ataaagagtt tgtatccttt ttcttttgct
    93421 tgtttcacca tttcgatcat gttttcgatc gtattgtatt tttctaagat atcttttgtc
    93481 aaactaaagc caccgcctgc tggtttcaag aactcgactt gcgggtcagt gagaactact
    93541 gctgtatttt tattattgaa catggtggat tctccattcg ttatttattt taatacatca
    93601 tttaaagctt cactcattgt tggatgagaa tagatttgat ctctcaataa cgtataagga
    93661 agttttccat tcatagctag cgaaatcaag ttgatgactt catgagaatc ttccgcatag
    93721 atacttgccc ctagaatcaa gtcagtttca gggtcgacta aaactttgaa tacaccttta
    93781 ggatcttcta atacttgtgc tttagggaca ccgcttgtca tatacttgaa taatttgtaa
    93841 ttgacgcctt gtgctttggc ttgtttttct gttaaaccta cattggataa agtcggagtg
    93901 ataaatacac tgtaaggcac agctttccgg ttattcgttg ttcgtttatt ctcgcccttc
    93961 aactgatcca taatgattcg ataatcatct agagagatat aagtgaactg caatccgcct
    94021 ttgacgtctc caatcgccca aatgttgtct gcatctgtac gaaggtattc atccacagcg
    94081 attgctccgc gatctgttag tttaacatct gtattttcta atccaagtga tgctgtactt
    94141 ggttttcttc cagttgcagc caaaactttt gacgcttgga ttgttacttc ttggccattt
    94201 tctgtaaagg tgacggcagc tgttgattct tggtctgcta cttgatctac agatacacct
    94261 agatggaatt cgattcccgc atttgtcatg tcttctaaaa tcatttgcgc gatatcttca
    94321 tcttcacgag gaagaaattc aggatgggca tcaagaacga caactttaga tccgtattca
    94381 ttgaacattg atgcaaattc caagccaata tatccagccc cgatgatcac taatttttcc
    94441 ggtaattgtt cctgatccat cgcttgcgta gaatcaatca agtagcgact tgtattcaat
    94501 cctttgattg gtaaaatgat tggttcagaa ccagtattga tgaaaatccg ttcgccttca
    94561 acaatcactt tttcaccatt attcgtcact tcgatttgat ggttagaaag aaaacgtgct
    94621 gtaccgtcca tcactgtccc agttgcctca tcgctgatca tatgataatt tttggcgcga
    94681 agcatgcccg tcaatttttc tttccgagca acagcctctg taaagtcgat tcctctttct
    94741 ccattgaaaa tcaatgattt agaaggaata cagccgatgt tgatacatgt tccgccatac
    94801 atacgtgttg acttttcaac gactaaaacc gattcgcctt ttgaagctaa cgccttcgct
    94861 aaagtcttac cgccctttcc aaaaccgatc acaatatttt gatatttttc catccttttt
    94921 ccctcgcttc tttttttacc taccgattgg tacaaaaata tgataaccga taattgtcta
    94981 ttctccaaat catctgcttt atttgtcaaa aaaaaccaga caaaaagcgg tcctttcacg
    95041 tttttagtct ggttcgattt cctttattct tctaaacaat cgttacttct acatcgatat
    95101 ttcctctagt tgctttggag taagggcaga attcatgcgc atcttctgca attttttggg
    95161 cttcttcttc gctgatgcca tcgatatgca cttctaatac tacaccgatc tgatagccgc
    95221 catcatctaa attataaaga gagacacgtg cttttactgt ggactctgct gtcattcctg
    95281 cttctttgat catatgttgt accgccccat tgaaacaaga agcataacct gctgcaaata
    95341 attgttctgg atttgttcct tctgcatgga ttcctggagg agtgattttc atatgcatcg
    95401 agccatttgg tgcctcgact tctccattgc gcccgccatg gttgatcatt gctgtttcgt
    95461 atgctttttt cattgtactg ctcctttcga ttgaccattt gctacttggc tataattata
    95521 gtgtatgaca agtaaggcgc tttctacaaa aattctgctt attcgaatac cagaatgccg
    95581 tcttctacta tttttccaaa aaacaaaaaa atactactcg tgaacaacag cgtcatattt
    95641 gttccaaaat aaatagcaat cttttctaca taatctttta tatgattgat tttaagatac
    95701 atatatacca gaaagttgac cccataaacc aatactgtta aaaaaataac catattcgtt
    95761 accatttttt cctccttttg ctggtctccc taccagcact cgatttaacc ataccacttt
    95821 ttttgccgtc caagcaacta gcctttcaaa aagactggtt tattctgctg ttaatgattc
    95881 aagatcagaa aaatgtccga ataattttgc taattttact aacgccaact tgttctttcc
    95941 gaattcatca ttttctatct gtaatactag taacggctca tgtaagctta aacggatcaa
    96001 aaaccagccg tttccgtatg gctcttctag atcatatcga ataccttctt cattttccgg
    96061 gtcgaagttc atcccttttt cttcttccaa cagtcgcttc atttcttcta atatcttgtt
    96121 tccttgttcg cgtggttcat cgctgaacaa ttttaatcgg atttcttgta cttctacggg
    96181 ctgtttcaac tctttgattt gttcatctaa tgtgatacct tttcttttta attctggcaa
    96241 aagcatcagg atctttgcga tgacatatgc accatcatcc agaaaatagt tttccttgaa
    96301 tgcagcgtgt ccgcttgttt cgatggctag ctgtgtatct ttcccaagac ggttaagttc
    96361 taatgcttta ttgattacat ttcgatagcc ggaaatataa cgaacttgga tgcctccttt
    96421 ttcttcaatg aatctttgta gatgagaaga agtaggggaa ttcgtcacga ttcttgttcc
    96481 tggatgctct tttaatacga ttgtacttaa tactgcgatc aaattatttc gattgatcac
    96541 tgttccagaa gcactgacaa ctgcagaacg atccacatct gtatcgaaaa tgatcccaag
    96601 atctgcttca tttgctaaaa cagcctgctt gatactttcc atcgcttctt tattatcagg
    96661 atttgggata tgattaggaa atcggccatc tggttccaaa aattgggaac ctgttgaatc
    96721 cgcacctaag ctattcaata ctttttcagc aaagaatcca ccagcaccat ttccggcatc
    96781 aacaatgatt ttccaaccat ttagtggttt gctttctagt gttccaatcc cctttttaat
    96841 ttttgtgact aaatcttgcg cataaggtgt caaaaggtct gctttttcta cgcttccagt
    96901 ttgttcgctt tttatttttt gctgctgtga taggataaaa gcaatatctt ctttttctgc
    96961 tcctccttct gaggtaaaga attttattcc attataataa tagggaagat ggctagcagt
    97021 cagcataacc gcagcatcgc acgagaactg ttcaaattga gtggacataa acatagcagg
    97081 cgtagtagct aattcgaaat cgatgacatg tatcccttgt tctttcagac tttggatcaa
    97141 cgcctctttc agtgctggtc cgcttatcct actgtcatga ccaatcccaa tcgtccattt
    97201 tttatttgga tcggttgatt tcttcttttt ctttatccag tttgctagtc cccagccgat
    97261 cttttttacc atgtctgtcg tcaagtttac ttcatatcct tcaactggta atgcgattcc
    97321 tcgaatatcc gatccatttt gcagcgcttt catatctttc atataaaagt cctcctcatt
    97381 tattccctca ttttttccag cttttctgca aatcgctgtg cttcttcttc tgagcggcaa
    97441 ataataatga atgtatctac accggccatc gttccgacaa cttcagggta agccacttca
    97501 tctagccaat tcgttaccac atcggcacca tttcgttcag tcaatacgat aaccatgaac
    97561 tgaacagact ggatacgcaa aacctcgcgt ctaattgctg tacgcaaacg ttcttcattt
    97621 aaagaaacag atggctggtt aaataatgta tagcgtacta ttttgttttc attttgactt
    97681 tttactaact tcatttctcg aatgtctcga gaaatcgttg cttgagtcac atcggcgcct
    97741 gcttcatgca gccgcgcaag cagctcttcc tgtgtcccaa taggttgttc tgtaatgatc
    97801 tggcggatca gtgcttgtcg ctgtttcttt ttcatattag acacctctca atgttgatta
    97861 tagcaaaaga taagtaatat ttcttcatat tttggtattt tttactttta ttttttgttt
    97921 tcattcaggt tgctaacctt tttctatttt aacacgcaaa atcgtcttca ttttttcagg
    97981 tgctgatttt cttggatcgc tgatgtaaat ctctttgtgt tctttagaag ctctttcata
    98041 gccttctttt gcgatgaatg cttctaattt ctcaaacgtt gctggttctt cggcataggg
    98101 cccgacgtgt aagatttggg cacaaagacc ttcttccatc tttttgaata ctacttgttc
    98161 tttcaagtct tccggaagtt tgctagaacg ctgaatggct tcttgtgcta tcgcttctgt
    98221 aacaaagtca ggctgtcgga tcatcaattg ataagaaaaa tgttcttttt tcatcactgg
    98281 ttcatgcaaa tacttttctt gcagtcccca ttgtccttcc agtggataga cagtatacat
    98341 ctgataatca ggaatcagcc aatttttttt aggcgacatg cgtattgcat agctgactgc
    98401 atatagacag gctactcttc gtttaaagtc ttcctgattc gggtcgccga tccctctgat
    98461 gctaaagaat gattttttag gaacctctag tatttgcggg ctttttttca tactatagct
    98521 cttgtcttta cgccattcaa ttttttccat ttttcttcct ccgcgaaatt ccatttagtt
    98581 atttattatc atacctcttt ttgagtgact tggctaatcg tgttgacact atttttcagt
    98641 ttgtgctaga ataagtgaag taaataaatc gtacagataa cacgtttcgg cgtgtcgaga
    98701 gagaggcggt ttctattttt ataatagaaa tcactctctt tttttacgaa attttttaga
    98761 ggtgatgtaa atgacaaaac aaaaacagct gcttttagta cctgcagtaa ttgcaacagg
    98821 gatgatgtct tttgcgggcg tattgatcga gacggccatg aatgtaactt tcccaactct
    98881 tatcagacag tttgatttaa cgactgcaca agtccaatgg gtaacaacga tttatctttt
    98941 gatgatttcg atcattgttc cgctgtctac ttatttgaat cgcaatttta gtctcaaaaa
    99001 actcttttta gcttcaaatc tgcttttctt ggcaggtata atgatcgatt tcttctctcc
    99061 taccttcatg gtcctattgt ttggtcgatt gctccaaggt gcagcgacag gtatcgctct
    99121 tccgttgatg ttccatatta tcttgacatt tgcccccctc aatcgacgag gcgcgatgat
    99181 gggtgtcggt actttgacaa cggccattgc tccagcaatt ggccccactt atggaggcat
    99241 tatgacttca cattttacat ggaatcatat cttcctgttt cttgtgcccg ttttgattct
    99301 ttctttgatt atcggctggt ttgctattcc cgagatggca gtacaaaaaa gtggttattt
    99361 ggattggata agcgttttag gaatttgtct tttgtttagt ggaagtctaa catttttgag
    99421 tacgttggga acagtttcca gctggattgc tttaatcatc ggcggtattg gctggttcct
    99481 tttttactat cgaagtaaaa aagtggagca tccactgatc cgactgtcta ttctttcaaa
    99541 taaaacattc cgcttgtttt tgattggctt cttagtttat cagtttttat tacttggtgt
    99601 atcttttgtc ttgccgaatt tccttcagat cgttcaagga agtagtcctt ttgtcgctgg
    99661 attagcgatg cttcccggcg cagcggttgg tgctttgctt tctccttttt ccgggaaaat
    99721 gctggatcaa tatggtccga agaagccaat ttttgctggg ctgattcttt ctttgattgg
    99781 ttggctagca ttattcctac tcataggaca cgcttcagtg ggtgtattga ttgcttgtca
    99841 tgtgttttat atgatcggta tcggattatc ttacagcaat atgatgacca ccggaatgaa
    99901 tgcactgaat gaagaactac aaggagacgg gaacgcaatg ttcaatacct tgcagcagtt
    99961 ttctggcgct gtggctactt cattagtagc ggtcattatc aattacgtcc agcatcatac
   100021 ttcccataac tatgaagtgt ctactacatt aggatcaaaa gcagcattag gcgtcttgtt
   100081 gctgttgctt ctcgtaagct ttgctcgatt cgcctattat ctgttctttg ctaaaaaagc
   100141 gtagattcca tatacggcag gtgttgcatc tgccgttttt ttgtgtgaaa atggttgttt
   100201 gtaaaaggag gcttttttat ggaaaaaatt gccattatcg gtggcgggat cattggtatg
   100261 accctagcca gttacttaga tacatcaaaa ttcaatgttg ctttatttga tgaagggaca
   100321 ggacaggcaa ctaaagctag cgctgggatt atctcccctt ggttgtcgaa acgcagaaac
   100381 aaacaatggt atcgtctggc taaagacggc gctgcttttt tccctaaact tataaaagat
   100441 ttccaacttg atcaaacgat ttacgcacaa tcagggacac ttttgcttcg acctgaaaaa
   100501 gatttagctg aattggctgt tcttgccgag aaacgaaaag aagaagcgcc agaaattgga
   100561 aacatcgaat ggctttcacc tgaacagaca tctcaagcac ttccgttatt gaaaccagca
   100621 gtttcactgc gtatcagtgg tggtggtcgt ctggatggaa aagcatattt agaacatctt
   100681 ggtcagcgtt tagcacaaaa acaaatggag cagatccagg caaaagtcac tttgcataag
   100741 aagagcgatt cttggctcat caagggaccg tttggagaat acacagctga tcgtgtaatt
   100801 ttgacacctg gcccggcact taagccttta ttacaagaat taggctatgc tgcagatata
   100861 cgtccgcaaa aagggcagct cttagcattt cagacatctt ataagatgag tcaagactgg
   100921 cctgttgcta tgcttgacgg agaagctgat ttcattcctt tcatggatgg aaagatcctt
   100981 ttaggtgcta cccatgaaaa cgatcaaggc tgggatttgg ctcctactag cgaagcttat
   101041 aagggattga ctaagagtac agaacagttc ttgactgatc cagatcagat aaaaaactgg
   101101 ccatacgagt tccgtgtagg tacccgtgct tatacgtcag atttttcccc atttttcggc
   101161 gtactgccag atgatccaag cttactggct gctagcggtc taggctcttc tggcttgacc
   101221 acaggtcctt atatcggcta tctattagcc aacttcttaa atactggtca ttggcctacg
   101281 gaagattatc aaaaggacat ctccacctat attacgaaaa atccatcata gaaaaacagc
   101341 tttttcaagt aaggatcccg agcgatattg cgcatggatt acttcttgaa aaagctgtta
   101401 ttttagttca atttctgaat caaattctcc aaactttctt ttgcttcatc tggcaagaga
   101461 tcttttccta tctgagcttc aatgaatcgt aaacgaatat caagtcgttg tttcaccaga
   101521 tttttatagg acgtatcctc aaaagaaaca ggaaaatctg gtataggtaa atagtggatg
   101581 tcttcaaatg gaccaaacga cttgaattct gccgtttgtt gcacgattct ttcaacgatt
   101641 gacaatgtcg tttcaggttt gattttttta tcatcgaaat atccagtatt caggacatag
   101701 caggctgttt gctgtttcaa aaacaactct cgaaaagctt gatagtcttc cctaagagga
   101761 tagacacgga aaggattagc aaatggttca atgactagct catctagctg tctttttgta
   101821 gtgatatttt ccgcgtctga tcgttttgtt gctaatgttg caccaaaaga cgctgctaaa
   101881 actgggtcat tgatcttgat aattggcgga agcgaatcat ctttcatgat ccaaaaaaca
   101941 gcatcgatct tttcgctaag atgatcgact cggtcgggtg tcgcataacg tgatttgact
   102001 gtccgcccat ttccgtttcg tatatctcct gttactagga ctttttctcc tttacttgta
   102061 catgtcacgc ccacattctg acaagtaagg aaagaagaaa tggccggatc atcagacgga
   102121 tagtcttgtg ttttatcaaa gtaagaaggt tccaaggcag tagcaaaacc attttttcga
   102181 gaaataacga aagcatcgtc atgcaagatc gaaacagagt gaccttccgt atgttttgct
   102241 aaggtaatcg ttgattttcc agaaccggac aacccaaata cagccatcgt ataggtctgg
   102301 tcattactag catattgttt catcccaccg tggcaggcaa taaagccatt gcgatttccc
   102361 aatgcccaag caagcgtcaa agtcgctttt tttaattctc caaagtaacg taatcctagc
   102421 acagccgctg tattatggag agcatcaaac aaaatgagtc catttggaaa tgtttcatgt
   102481 gtccattcgg gatcacaaaa gatataaaga tctccctcat caaaggaaac agacttttga
   102541 taagtctcta agatcttcga attcgctggc tgaaaattca gcaaataaga atacaaattg
   102601 ttctcaaatc cttctggaat cagcaaatga ctttgcacag aaaattcttc agataggcca
   102661 acgattactt ttgtatggta aaactggcgc ttgcgacttt gatacacagc ttctcttaaa
   102721 attttctcgt atttgctttg ttccttgtct aagtcctcaa agatccgccg agcacttgct
   102781 gttcttccca caatgcttcc atcattgaat actagtgtcc taacatcagc tggtaaatct
   102841 agttcttcag catgtgagat tgttaaatct gtgatgatcg ttcctggact cccttttgct
   102901 agttgataag ctgtcttcct atcaaaaact tcatgaacat tattaccgta aaatgtcgtt
   102961 tctacaatcg atcgaatact ggataacagt ggatttccac ttgtgatttc gtttaattcg
   103021 agactctctt ttgtactcat ggctcctcct cattccctaa acaaaaaaac gttttcttta
   103081 ttatacatta ttcgagtttt tatttgtact gctgcgctgt gggaagcaaa cgagttattt
   103141 ttcacacaaa aaaaccgaga acttgaataa acaagtttct cggtttcatc attttccttt
   103201 tatcggctta gtaccagccg tttgctaacc agaatgtttt agcagcatcc catgaaccat
   103261 aacgagatgt tacatattgt tctgctacac gttcttgatt ggcagctgaa tagtcgccgt
   103321 ttaagtatga agcatctaat tgataacggc cgatgtaacg tccgttagta gctgtgtatg
   103381 aaccgcctga ttctttttgt gcgatccatt cttttgcaga gcttgaagtt ggcgctgttg
   103441 cagcagctgg ggcagcagga gctacttcaa ctgtttcaac aggtgcaacg tatgtatgtt
   103501 cttgcgttgc tgtttcagtt gtagatgctg tattttctgt tgttttgttt tctgttgttg
   103561 ctgaagaatc atttgaagtt gggattgtta attgttcacc aacataaatg cggttgatgt
   103621 ttgcgatcga atttttttca gcaattgcat cgatcattga gttgtctcct gcaaattttt
   103681 gtgagatctt agataatgaa tcacctgatt ttactgtata aacttcatca gcgtgagcat
   103741 ttgtagttcc tacaaacatt gcagtagcac cagcagcaaa agttgtacct aaaacaattt
   103801 tcttaaatga attcatatta aactcctttt tttctccgtt ttttattctt tcgacgctat
   103861 taactttatc atttagaaat atttcatagg taaaagaaac atgacattta atgacaaaat
   103921 aacgaattat ttaatatttg taacatttaa acaaatattt ttttgataca aaaccataaa
   103981 agccttgttg tataagcaaa gtaatcgttt ttctatgttt ttttattttt gaatgaaaaa
   104041 cgcagattct gtaacattca ctgcaataat ccataaaaaa aagcaaaaaa atttttgatt
   104101 tttatcaaat tctcttaaaa aaatgtaaaa aatacaaaaa aaccagtaat tgttacaaca
   104161 attactggac aaaaactttg aataatgtta actatttttt tattttaact ttctccgcaa
   104221 taatttctgg gcatgttcca attcgtttat aacgacttct tctgtttctt tagctaatat
   104281 ttcatctaat acatcaagcc atttttccgg ttcttttgtt cctagacgtc caatagccca
   104341 agctgctgtt cctctgatga cagggcggac atctgttaaa cattctgaaa tctcaggcaa
   104401 tgccgttcga tcacctagat tagctaaagc aatcaatgcg tttctctgca aaggtttctt
   104461 cccacgccat gaaccagcta aatgcccaaa ttgctgtttg aagtctttat tagacatcga
   104521 aagcattggc tttaattttg gatatatttc gtctactttt ggttccatct cttcatgaaa
   104581 atgaaaatct tttccttgat tgtaagggca gactaactgg cagatatcac atccataaat
   104641 gacatttcgc atttttttac gatattcttc cggcatcatc ccttttgtct gagtttgata
   104701 agacaaacat cgctgggcat tcattcttcc gtcaccaagc aatgcttttg tcggacaagc
   104761 agtcacgcag cgcatacagt caccgcaacc aaattctcct ggtttatcag gctcaaatac
   104821 aatattagta acgatctcac caagatagac aaatgaaccg aactcttcag tgatcaacaa
   104881 tccgtttcgt ccaataaatc ctaaaccagc tcgctgtgct acagcgacat cgatcagttc
   104941 tccagtatct acttgcggag ctagacgcca ttcctcttct ttttgccatt tttctgctct
   105001 tgtttggatg aattcgatca atcggttcaa acggtctctg agtatatcat ggtaatcgat
   105061 cccccaagaa gcacgagcaa actgcccgcg tttttcatcc ctaggcactt cttcatggat
   105121 cctagtagga tacgcaagtg caatggaaat gatcgatttc ggctgatcaa atgtcatttc
   105181 tggataaaga cgctcatcga tatttggatg ttcaaagcca gaagtatggc cagctgcttt
   105241 ttgttcttcc aacgattctt ttaatgaatc aaaaggttcc gccgtggtga acccgatttt
   105301 gtcaattcct aatcgtttgc tttcttgtat gatttcttct tttaatgtca tggtcttcct
   105361 cgcttgctgt taacggctgt ataacccata atatagtttt tcttttttca gctggacaaa
   105421 ctggatctgc tgatcggcaa tcttcttttc ttccatccat ttttttcttg cagcaaatac
   105481 ttcccaataa tttgttgaaa ttaattttct tttgttatct aatgcattaa aaaaattcaa
   105541 tgaaactggt tttgtactta acagttcatg gagccttacc tcttcccatg gcgaaaactc
   105601 agacagatcg cgggaataca atacttcttc atagagattt ttttgctgtg tgtacgtgaa
   105661 tgtttgcggg attttcccag gcctagcaat ttctactaga cgattataaa acatattcat
   105721 taatttgctg ttggcaataa attgactttt ataataggcc gactggatct ttttgattac
   105781 tccttctgct ttgatgactg aaaataatgc aggccatgct ttgacggtta tttcgtcgtt
   105841 ttgtttaact aatacgccag gtgtgaagcc gactggagaa aggaacacaa aataaccgat
   105901 accggtattt tcatctaaag gctgaaattc atcaaacaac catttgccta tgtacagctc
   105961 ttcatctggt tctgttgtct cattttgatt tgctatgaat aatttagcta attctgcttc
   106021 aagaaattga aggtcttgat ccttgtcggt attttcctgc tggctgatca atcgaaagac
   106081 ttcttcttta atcgtatatt tatctttacg tgtaaaattc atagccacac cttccttcct
   106141 tactctaact ataacggaat ttcttcaaaa aaggtatctg tacgacgaaa aacagcataa
   106201 ttttttttca tatctcttat aaaaaatgca aggtctgctc ctcaagctag accttgcact
   106261 tttcagcttt cttttgtttg tgacaaacct tcatggatcg tttcaatatt ccatttcatc
   106321 atctgatagt aagaatctcc ttgttctcct tcttttgcta tggaatcagt gaacagttta
   106381 tcatagattt tcaaacccgt ttcttttgct acccgttcca tgcttcttga gtctacactg
   106441 gtttccacga ataaaaccgg tacttctttt gctcttatct gatcaatgat cgctttcatt
   106501 tgatcaggcg taccttgact ttctgtattg atctcccata tataagctgc tggcaaatca
   106561 tatgctcgtg aaaaatactt gaatgcccct tcacttgtta ctaataattt tttgttctct
   106621 tcgatagaag caaaactttc cttcgcttgt gtatctaatt cttttagttt ttccacatat
   106681 gcttctgcat tttttttata gagtgtcgca ttttctgcat ctttttcaga gaatatacgt
   106741 gcgatttcct ccacatattt tattccgtta gataggtcta gccaagcatg gggatctgct
   106801 tttgtatgtt cttcaccgct agttaaataa agaggttcta catttttgct aactgcaaaa
   106861 taatcttttc cttcttcttt tttagccgtt tccatcaagt tatcgaacca gctgttacct
   106921 gtttcaagat tcaaaccgtt gtataaaata acatctgcat cgcttgcctt tttgatgtct
   106981 tctggtagta cttcatattc atgcggatct gttccgactg gtacgatact gtggatatct
   107041 atttgatctg ttccgacctc ttttgccatg tccgccaaga tcgaattggt agccacgact
   107101 gacaactttt ctttacttcc ttcatccgct tggtcagaag cctgctttcc gcaaccggct
   107161 aataccaaga aactaactgc caagattaaa aagagtgatt tttttgtttt catctatctg
   107221 cttcctttct gaaataaaat tccttttgtt ggagaaaata aaaaagcaag gataaaaaat
   107281 gcggtacatg ctaacacgat cgtagctcct gatggccaat tgtaactata actgaaaaac
   107341 acaccgacaa ctgcacttag cataccgatt cctgcagctg taatgatcat tttcagtaaa
   107401 tggttcgtta gcaagtaagc cgtggcggct ggtgtgatca acatggcaat caccaagatt
   107461 gttcctactg tctgtaaact gactacagcc actaatgtca aaaagaacat caaaagataa
   107521 tggatcagcg atgtgttcag cccataagct tttgccattg tcggatcgaa tgatgtgatc
   107581 ttcaattctt tataaaagaa aaagacaaat atcaagacga ttccactaac gagtgctgtc
   107641 agcaacaaat cgctttccct aacagctaag acattcccaa ataaaatatg atacaaatct
   107701 gtcgcactct gggcatatga aatcaagata atccctaatg caaaaaagga gctaaagaca
   107761 attccaatcg ctgtatcatt tttcaatcgg ctccgctgag tcacgaaacc aatcactgct
   107821 gctgttagca tcccaaaagc agtggctcca aagatgtaac taaaaccaaa catataagaa
   107881 atggctacac ctggaagaac tgcgtgagag atagcgtctc ccatcaaaga catccctcgt
   107941 aaaataataa aagaaccgat gactccagaa gcaagtccta caagcatgga agtgaccaaa
   108001 gcgtattgca ggaattgata attcattaat ccatcaataa aggattggat cattttttct
   108061 ctcctccttt tactaaatgt ctgatgatct caccataggc caattgaagg ttcttcgatg
   108121 taaagacttc ttgtactgga ccggaagcga tcagctgttt atttaaaaga ataacctcat
   108181 cgaaatattc ttctacttta tgaagatcat gatggacgat caaaatcgtt tttcctgaat
   108241 tcttcaattc ctgcaagatg tcaaagatct ttcgttcact taacgcatca atccctacga
   108301 atggttcatc taaaaagatc cattctgctc cttgggctag agctcttgca ataaaaactc
   108361 tctgaagctg tccacccgat agttcgctga tctgtctttt ggcatattct tccatcccta
   108421 cttttttcaa agcttgtctt gcacgttctt tttctttttt cccaggtctt tgtccaattc
   108481 gtaaagatgg atatgttcct aaaagtacaa cgcctaatac atcaattgga aaggaaagat
   108541 ccaattcact tcgctgttcc acgtaggcta tttttttacg gactgagttt accggctgtc
   108601 cagaaaaggt gactttacca gtagtagctg gtatcaactc tagcaaagat ttcataaatg
   108661 ttgattttcc tgcaccgttt ggtccgataa taccggtaat tttttgtgga tttatcgtca
   108721 agttgatagt tttcaaaaca gttttccctt gataagcggc tgaaaggtct tgaattacaa
   108781 tggccgtacg ttccaaatct tacactcctt tttaggttta cctaactttt tatttaaata
   108841 tagtttaact aaaatggaaa gcattttcaa gtagaatgat gaaaaagttt ttttcgaatt
   108901 ttcctcgcat tttatgaaaa ttttctgtag aatcacatca agagttcaat aaggctaacc
   108961 taataatgaa aaacatgtgt tgaaacgttt gattattttt tcttgttgac tcaacaacga
   109021 aaggagtttt tgtatggaag aagaaaagtt aactcgaagt cttagtgccc gtcatatcca
   109081 aatgatcgca ctaggtggaa cgatcggtgt cggtctgttt atgggtgcct cctcaaccat
   109141 acgttggaca gggccctcag tgatgggagc ctatgcgatt gcaggattct ttttgtattt
   109201 gattatgcgt gctttaggcg aaatgcttta cgttgatcct tcgactggtt cttttgcaaa
   109261 ttacgcgagc gagtacatcc atcctgtggc tggctacttg accgcttgga gtaatatttt
   109321 tcaatatatt gtcgtaggaa taagtgaagt gattgctgta ggatcttata tgaattattg
   109381 gtggcctgat ttgccggcaa ttattcccgg aatcattgtc gtcttgtttc ttatgctggc
   109441 aaatcttatt tctgtcaagg cgtttggcga attagaattt tggttttcga tcatcaaagt
   109501 cataacgatc attttgatga tcattgcagg tcttggggta atcttatttg gatttggtaa
   109561 tcatggtcag gcagtaggga tttcaaatct ttggaaaaat ggtggattct tcactggagg
   109621 cgtcaaagga tttttctttg cattatcgat cgttgttgct tcctatcaag gaatcgaact
   109681 gatcggaatg actgctggtg aagcagagaa tcctaaaaag acgatcattg aagctgtcca
   109741 gtccactatc ggtcgaatct tgatttttta tattggtgct atttttatca ttgtgagtat
   109801 ctatccgtgg aatcaattga gtgagattgg ttcacctttt gtacaaactt tttctaaagt
   109861 cggcattaca tttgctgcag gactgattaa ttttgtcgtg attacagcgg cattatcagg
   109921 ttgcaattca gggattttca gcgcaagtcg tatggtctat acacttgcca taaatggaaa
   109981 gatgtctaaa aaatttctga aactatctcg tcacggtgcg cctttttatc ctgtcgtagc
   110041 aatctcaggt ggaatcttaa ttggtctgat cttaaattat cttctaccaa tgttcatcaa
   110101 ccagtcagaa aatattttcg ttttcgtata cagctcaagt attttgcctg gtatggttcc
   110161 ttgggtagtg attttgatca gcgagattcg cttcaaaaag aagcacgcag ataaaatgca
   110221 tgatcatcct tttaaaatgc cactatctcc ttatacgaat tatgtgacac ttgctttttt
   110281 agctatcgta ttgattttca tgtttatcaa tcctgaaacg agaatctcat tgattattgg
   110341 actcgttttc ttgctttaca tgacgatcca ttactttgta cgcgaaaaaa gaaccggaaa
   110401 ataaaaaaag aacgaagctt caccttagtg gaagcttcgt tcttttttat tgcttttatc
   110461 aattcaattt tagcgtctca ccgggagtca ggaaataatt ctccatgctc atcccattca
   110521 gcgacaagat cgtttctact ggtacgccag ttcgttcggc tatttgattt ggaccttctc
   110581 cttccaaaac tacggttgtc gcagcctgtg aagtcgcgct gttggtatta gtttcagagg
   110641 aatctgttgt gtcttgtgtt gttcgagctt gcatttcaga agcttctacc gactctgctg
   110701 tctcagaatc agaagatgtt gtgtcttgtg tgcttgttga ctctgcttga agagaggcgc
   110761 tagtctgcaa ataaatatcg gaaatcttag cgacatgatt cgtataatta gccgataatt
   110821 gattgatcaa agtatctaag tctacaccgt ctttattttc tgctgcctga tacgctgcac
   110881 gtaattttct gatcccttcg tcggagattg cttgaagctc acgtgctttt tggttagcaa
   110941 ctgctgataa accagctatt ccctcttgat ttccctgaat ttctgtctgg tattcttcaa
   111001 tcaatgcagg cgtcttttct tcgatctttt tcgaataatc atttacgatt gcttgaagtt
   111061 gctctggcaa accatttgct gttttttctt cagaagtttg tgtctctttt gttttagttg
   111121 atgactcact tgtttgtttc gtctctgttt tctttgtcgt tgtttccgtt atggtcgtac
   111181 ttttcgcttc tgacgaattt tttccatgaa aatatagacc cgcaactcct cctgctatga
   111241 tcaaaaacac ggcaactgct gccccaatca tgatcatccg cttacgagct gcctgttttt
   111301 gctgtcttct tcgggtcatc cgaacatttt ctccccactc attttcatca tacatttttt
   111361 tcaccaccaa tttttatgta taatagcgtt atcaaacgct tcatattctt attgtagcaa
   111421 ataattgtcg ctgtgcacat ttttatcttt gttatttata agaaaatttc accagttgag
   111481 atgattccaa gattgtccgt cgatttctcc ttgcagctgc attgttcgtt cgtctatctc
   111541 agccatcagt ttctttattt catataagag cgcacggtct tgatattctg atttttcgct
   111601 taattcatct aattgttgga tcagccaatc atttgtcata atgaagttcc tttcatttct
   111661 tgcagtgtaa aggtcaagtc ttcgatctgc tcttttgcct cagtcagtgc ttctacgata
   111721 tatgcttgtt tttcagattc ttcttcctgc attttctgat tttcctgtac tctttgaata
   111781 aaccagtcaa tccgctgagt cagcgatggt ttgccttcca atgagagata ctgctgataa
   111841 gcaattagct tctcccaacg tttttcctgg gataaataca taaattgtgc taaaacgaat
   111901 ggcggaagat aggtcatatg gaatttattt gcgattcgct gatacggcct caaaaattcg
   111961 gaaatcgtat attcttcttt tcctccagct tggtattctt tttccgccac acctgttgtc
   112021 aatacgattc ctagttcttt cccttttaat acatgtgctg ctcgttccaa gacattatct
   112081 tgccaaattt ttaaatgagc aggagaacta taccagtaaa acggaaactg gaaaatgatc
   112141 cgatcatgct gggccaagag ctgtagttca gtctctatat ctatttttcc gtctggataa
   112201 cttgattcca aatgatgcca agtagctggt aaaccagcag aagcttcttt gaaaaattgc
   112261 tgatttaaag attcttcgat cgttggatgg ctaatgatga taagtgtacg catccctttt
   112321 cctccttttt agtcttcgct ttacagtgta gcataaccgc cacaagtttc ttttgccgat
   112381 gcttgtcatt ttaaccagac taatcaggtt gtccaagaaa ctgcggtttg tttttccaac
   112441 tgttttttca aggtatccaa agcaatattc ttaaaatttt cgtttttcat acgtttacga
   112501 tagttcgtag ccgtttctcc ggtactcttt ttgaacattc ggctaaatac gactagacta
   112561 ttgaacccta cttgataggc aatactttcc acggattcat ccgtcagaga aagaagaaac
   112621 gcccctcgat tgatccgtac cccgatcaaa tattccttga tactggtgcc catatgattt
   112681 ttgaatactc gcgacaaatg gctccgattg accgctaaat gctgggcgat ttcctcaaca
   112741 gacaattttt cagcataatg tgcctcgatg tatttgactg tttcaacagc taaagaggaa
   112801 tgaacctttt gtacacctcc gctgaccttt ccgccatctt ttaaaaggac tgataaaaaa
   112861 cggtaggtta atgctgttaa ctgtaattca ttttccaagg tttcttccgt atctttcatg
   112921 cattctaaaa taatgtcgat atatttttgt atgtcagaag agaccatcgt gtattggtct
   112981 tctctgaaaa gcgactgccg aatgatttct tctgcagcac tcccaccaaa tgaaagccag
   113041 caatacatcc acggatcttc tccatctgat aagtaaaacg tcgagtctcc tggacgaatc
   113101 aagaacagat cacctttttt caattggaat tgttgatttt tcacatgata agatcctttg
   113161 ccttccatca cgacatgcag gatgtaatca ttgcgaatag caggaccaaa agaatgaaac
   113221 ggcatcgttt tagagaaacc acaaaaatca aaatacaatt ctttttctac ttgttgatgt
   113281 tcctttttta aaaaaatcga ttgctccacg tctatccctc cttactcctt tagtataatg
   113341 caacaaaaag ttaaataaaa gtcacagaaa tatattaaaa aggaagcgat ttcttgttaa
   113401 gtttaagtca ttaaaagatc tttgttattc gttgtaaccg gtttacttag tattatatat
   113461 tgaacaggag aggaatacag attatgaaaa gcaaaatgat ccaacgtgtg tcctacgctt
   113521 taggcgcttt tggacacgac acattctatg ttacattaag cacttatttt atggtattcg
   113581 tgacaagcca gatgttcgca ggaacagata aggcaacgaa tgcaaaaatg attgctacag
   113641 ttacaagctt agttgtaggt atccgcttag ttgaaattat ttttgatcct ttgattggtg
   113701 gcatcatcga taatactcgt acaaaatacg gtaaattcaa accatggtta gttatcggcg
   113761 gcgttgttag ttccgtactc ttggtagcaa tctttaccaa tttctttggc ttagctactc
   113821 ataatacgac tttatttatc atattatttg caatcgtttt catcttattg gatagttttt
   113881 attcatttaa ggatatcgct ttttggtcaa tgattccagc tttgagtacg gaaacaaagg
   113941 aacgtgaaaa atttgctacg tttgctcgtt tcggctcttc tctaggtgca aatggtacta
   114001 ctctagtcgt tgtccctatc gttactttct ttacctatct tgttactcat aaacatattg
   114061 aaggcgcttc aggctggttc tggttcggtg tgattgctgc tgttatttca ggcggtactg
   114121 cgattatcac tgccttgggc acaaaagaag tcgatactgc gatccgtcag caaaatgaaa
   114181 aagctgggat caaagatgtg ttcaaagcag ttgctcaaaa tgatcagttg atgtggcttg
   114241 cccttgctta tatcgcttat gcgattgcca atgtagcaac aactgccgta ttattctact
   114301 tcttcaaata tgtacttggc caaccaactg aattttggat cgttggtcta gttgctgcct
   114361 tacttggttt agtagctgtt ccactattcc caatgcttac acgcgtcatc tctcgtcgct
   114421 acgtttacct tggagggatc gcaatgatga tttcttctta ctttttcttt acgatcgcag
   114481 gttcaagttt gccaatcgtt atcatcgggc tagtattgtt ctacttccct caacaattga
   114541 ttttcttatc cgctttgatg acgatcacag actctgttga atatggtcaa tggaaaaatg
   114601 gtatccgtaa cgaagctgtt actctatcaa ttcgcccttt actagataaa atcgctggtg
   114661 ctttgtctaa cgggatcgta gggtttgtcg ctatcgcttc tgggatgact ggtaatgcta
   114721 ctgctgctga tatcactgct catggcgtaa cgactttcaa agcttatgca ttctatgctc
   114781 ctgctgcttt gatgattttc tccgctatta tttttgcttg gaagattaca ttgacagaga
   114841 aaaaacatgc acaaatcgtt gagaaattgg aaaacaaatt ggctccagct gatacaatgg
   114901 aagatgaact tcacgatgca gtagttcctt cccattaaga aaggatcttg aaaatgaaga
   114961 ttacagaaaa agattttggc caaggttatc acttgataac cttggagaac aaaaacaagc
   115021 tagcactttc tatctctgat ttaggtgcta gaatcgtcag tttaaaatca aatgatcgag
   115081 aattagtttt gggatttgac accgctgaag aatatatcga aaaagatccg tatatcggtg
   115141 cttctatcgg tcgcaccgca gggagaatcg aaaatggccg cttttctctc aatggaaaaa
   115201 cttaccaatt agccacagat ccaaaaactg gacataatct gcatggtggt gctcctggat
   115261 ttgaattaaa aaaatggtct tatgtcattt tgaatggcga aaatgaagct tctgtcattt
   115321 ttactactac aagtcccgac ggagaacatg gttttccagg tacaatggat gtggaaatcc
   115381 gctatacttt gacaaaagat aatatctggc gagtgacctc tcgcggcacc agtgaccaag
   115441 atactttatt caatccgaca aatcatgttt acttcaactt gacgggagat gcttctcagt
   115501 caatcgatca acatgagctt tggctcaata gcgaagctta tgctcctttg cgaacagata
   115561 gtattcctat aggggtaaaa gaaaatgctg caggaagtgc tttcgatttt caaataccta
   115621 aaaaattagc gtccgttttt gctagtgatt tggatcaaaa aaatcttgtt gacggaatcg
   115681 atcatccatt tttcttaaaa gaaaccggct tgggtaaaga agccgctcgc ttgactagcc
   115741 ccgataaaag aatccaagta gatattgcta cagatgcttc tagtgtggtt attttcactg
   115801 caaatttcgg cacagaaaca ccagaaatgc gcaaccgaaa actggcacat cacggtggca
   115861 tcacatttga gactcaaaca gctccaggtg cagagcgctt ctcagcattt ggttcgattc
   115921 atttaaaagc cggatcagta tttgaaacag tgacagaatt caaaatcaaa acaagaaagg
   115981 aataactcat catggaaatc aaaagaagct taaacacaaa atttgccgaa acattcggac
   116041 ctaaaaaaac tacacaatac ttctcaccag gacgcatcaa tttgattggt gaacacacag
   116101 attacaatgg aggccatgtc ttccccgctt ccatcactta tggaacgcaa ggtgtagcag
   116161 cacctcgaga cgataataaa atattagttt attccacaaa ctttgacgat atcggtgtca
   116221 ttagttttac tttagatgag ctagaatatg ataaaaaagc aaactgggca aattacgtaa
   116281 aaggaatggt ccttaaatta aaagaagctg gacactcaat cgatcatggg tttgagttat
   116341 tagtggaagg aacaatccct aatggtgcag gactttccag tagcgcttca ttagaattat
   116401 tagtaggtgt tgtattagaa gatctgtttg atttaaaaac agatcgcttg gaactagtcc
   116461 aaacaggtaa aaaagtagaa aatgaattca tcggtgtcaa ttcaggtatc atggatcagt
   116521 ttgccatcgg cttcggtgag ctagatcatg caatcttatt agatacaaat acgctgaaat
   116581 acgaaatggt tccagtgaaa ctagatggtt atgcaatcgt catcatgaat acgaataagc
   116641 ggcgggaatt ggcagattca aaatacaatg aacgccgtag cgaatgcgaa gaagccttgg
   116701 cacgtttgca aaaaactttg cctatctctt ctttaggaga cttagatgaa gaagaatttg
   116761 aatcaactat tgaccaaatc ggcgatgata cattgatacg cagagctcgc catgccgttt
   116821 ctgaaaatca gcggactttg aaggcaaaag ctgaattaga agctgggaac ttagaagcat
   116881 ttggtcaact gttaaatgat tctcaccact ctcttcgcta tgattatgaa gtaactggga
   116941 tcgaattaga tacactagta gatgctgctc aaaaacaaga aggtgtctta ggtgcacgaa
   117001 tgacaggagc tggatttggt ggctgtgcga ttgctcttgt caaagaagaa aatatacctg
   117061 ccttcaaaaa caatgtctat gatgaataca tgaaagttgt cggctatgct ccggaatttt
   117121 atgttgcaca cattggaaat gggacaacaa agatcgatcc agaagctgtt catgtttgat
   117181 aaaaaaatca acgatctcag ctaaaaacaa atagataaaa ataacctctc agcaatttcc
   117241 aaatgtgagc cttttgctcg tatttgaaaa ttgctgtttt ttattgacac ggaaagagaa
   117301 cgtgtgttct aattgtgttg aagaggtgat tgttatgtgg gcgaatcaaa atccggtatt
   117361 tgtttatgaa aaagaacctt caagagatat tttatgtatt gactgcaaat ctttttacgg
   117421 tgcgaaacgt tcctaactga aaaggttagg cacacaagat tttcttgtgt agaactaatg
   117481 atttgaggag tgaaatgacg gtgtaacgac ctgaagcgct ccctctgata ctccgattgg
   117541 caatacctta agttagaata ggaattgtca aaagctcggt aaagtcggct gagagttacc
   117601 gcagttgcat tatgcaatcg aaagctgttc agcggtgaat ggtgtaacct ataggccggg
   117661 agtccagaaa ttactcatgg tgagaatgtg cagctgcact gacgaactcg cgaatgtacg
   117721 aatctataag cttggggtac agaaatgtat cttacccgca caaatattac tgtgacaaag
   117781 ggtgtagctt gcggttaagt aagaatcgta gatatgaaca accgtgcaat gtagtaggca
   117841 ttggaaagtt acaggttcag agtgagcgcc taaaagtaaa tgcagggata aaatcattgg
   117901 aacgttgaaa gctagtgtcg tggaggacta acttcctttg aaacggttga gacgaagaat
   117961 aataagctca tttacactag tgagagtagt ggcacagtac ctatgaagca gtgataataa
   118021 gctgtggagg gatagccaca agtcaatttg ctttactaac agttatgata caatccatag
   118081 aatcgagtat gacaaaataa acgccgacgt ccgaaaggag gcggtgctat ggaaaacgta
   118141 tcagcatcac attcaattcg ccatatggaa tattatggtc ttattgatag ctttgattct
   118201 ctttacaaag agagtagcga gaacaaaatt ttcagtaacc ttatggaaat tgtcacttct
   118261 cctaataaca ttctattggc atttcggaat gttaaaggaa attctggtag tacttcccca
   118321 ggcgtcgaca aaaagaatat tgatgattta aaagcaatac cgaatatcga gtttataaaa
   118381 actgttcaaa caaaattttc agaatataaa ccgcaaccag ttaaacgagt agatattcct
   118441 aagccaaatg ggaaaactag accactaggt ataccaacaa tatgggatag aatcatacaa
   118501 cagtgtctac tacaagtttt agaaccgatc atggaagcaa agtttcatga taagaactat
   118561 ggtttccgac ctaaccggtc ggcacatcat gcattcgctc aagcagtacg aatggcgcaa
   118621 ctttcaaaac taacttttgt agtagacata gacatagaag gattctttga taacgtaaac
   118681 cattcaaaac ttattaaaca gttttggaca ttaggggtac gtgataaatg gcttctaggt
   118741 gttatccgag caatgcttaa agcacctatt attcataggg atggacgcat tgaacatcca
   118801 aagaaaggaa ccccgcaagg cggtgttctc tctccacttc ttgccaatgt tgttttgaat
   118861 gaactggact ggtggatatc ttctcaatgg gaaacacacc cgactaggaa aaactacgat
   118921 tgttatcatc aaacaagaaa gcaatggatt aagagcaaca aatatcgagc actgcgtgct
   118981 tcgaaactaa aagagattta tattgttaga tacgcagatg acttcaaaat cttctgtaga
   119041 aaacgaagtg acgcagacaa aatctttcta gccactaaat tatggttaaa agaccgactg
   119101 aaacttgata taagtgctga aaaatcaaag gtagtgaatc taaagaaaca gaaatctgat
   119161 tttctcggat tcacaatgaa actggtacgc aaaagaaaaa gctttgtgat tgaaacgcac
   119221 atgtgcgcca aagccatgag tgcagcatct aataagttag caaaacaaat taaggtgatt
   119281 caacattcac ctacccaagt tgaacttcaa aaacagttaa gtatttataa ctcaatggta
   119341 gtaggtatcc atcaatatta taaaaaggca acccacatca gtgtggactg cccaagaata
   119401 aatcaacgcc taatgattat catcaaaaat cgactagata ttaagagaaa gggtcctcca
   119461 ccgagtgatt ttattaaaaa aaattacgct cggtcaaagc agttgaggtg gcttaatggt
   119521 gttcctatgc ttccttttgg attcataaaa catagccaca cctccctgcc caagatagga
   119581 acctgtaaat acacgcccga aggtcgtgtg ctgatacaca ggtatcttac tttcccaatc
   119641 gatattatca accaactcat gaacatgtct aatcctaatg aaagcattga gtttagagac
   119701 aatcgtgtat ccaagtactc ttcccaagtc ggccgttgcc gagtaacgaa agaagtctta
   119761 gagctagcag acatatactg ccaccgtatt gtccctaaaa atctaggtgg gaaagacaat
   119821 tatcaaaatc tggtcattgt ccaccggaac attcactcac ttattcatga agaggataaa
   119881 acaagagcat cacttctcat acaaaacatg agagttacaa gtgctcaact tgagataatc
   119941 aaccagtttc gcaaaaaagc taagaatcgt gaattgtcgc tgaatctata actgtatgat
   120001 actgttagta aactttgatg gaacgccgta tgcggtgaaa gtcgcacgta cggtgtggag
   120061 cgggggaaaa tctggagatt gcatcaaagg attacctatc gctatcctcc gtagagtgcg
   120121 ttgaaaagga tcttgatccc cttacaacta aattagtagt catgtcctat ccgtccgatt
   120181 cgacagaaac acggggtagc ggattaatct tggcttccag tcctgcagca aaaaaagctt
   120241 acggcatcac caatatcagc cgtgccagag atcttccctt cccctatcca agtgatttat
   120301 atattgttgc cccaaggatg gcctattata tggaaaagaa cagagaaatc aattctatct
   120361 ataaaaaata tgcagacgaa gcgaaccatc atgtctattc cgtcgatgaa agcttccttg
   120421 atgtaacaaa tagcatggca ctctttggta aaacaaatgc gtacgacatg gctaaactga
   120481 tccataaaga tgtgtttgag cagaccggaa tctacacgac tataggaatt ggcgataacc
   120541 cgctacttgc taaactagcc ttagacaatg gctcaaaaga cggaaagcaa atgtttgctg
   120601 aatggcgtta tgaagatgta ccagaaaagt tatggaaaat ctcagatatc actgactttt
   120661 ggggaatcgg caaacgaaca gcaaaacgtc tgaaacaaat gggtatacat tctgtttatg
   120721 atttagctca cgcggattat tatcacttga aaagcaagct aggggtcatc ggtactcagc
   120781 tttatgccca tgcttggggc atcgatcgaa gttttttggg acaagaatat acaccaaaat
   120841 caaaaagtat cggaaatagt caaatcctag atagagatta tacaagacga gaagaaatcg
   120901 agatcgttat caaagaaatg gccgaccaag tcggcactcg cttgagacga tctgcagcaa
   120961 aaacacaagt agtcagctta tgggtaggat actctttagg ctatcttgat ccaaatggca
   121021 agaccgggtt tcaccagcaa atgaaaatcg aagcgacaaa tgctagcaga gatctagcag
   121081 atgctttatt gaccattttc caccagcatt accactacca ggatattcgg cgtgtaggcg
   121141 tgaactgttc cgacctcgta tacgcgacag gtttacagct taaccttttt gaagatcctg
   121201 aaaagcagat aaatgaagcg aaagttgatt ttgttgtcga tacgattaga aaaaaatacg
   121261 gctttcaatc aatcatccat gcgcatagtc tcttgcaagg aggacgcgcc atcgcacgta
   121321 gttctctcgt tggcgggcat gcaggtggta tgagtggatt agaaggtgga aaagatgaga
   121381 cggacagcaa aaaaattcat tgactataac gagtatcgag atcggccatt tggattaaaa
   121441 tgggggactg cttttgcgat ggaagaacta gtcaacggta tcaaaaaaaa tgaagaagaa
   121501 gcacgcaaac agcctcttcc taaacaacaa atgacattgc aagaaatcga tagtatactg
   121561 acagaagcct ttttatctcg taaagcagta atcattcagc tcaatttaaa agatgaattt
   121621 ggaagactct tggatgaggt cgaagggcac ttcattggtg aagcctatga agattacttt
   121681 atgattgacc atcagccgat attgtgggaa gacgtacggt atattgagtt aaaggaaaca
   121741 aaaaaatggt ttgtgacatg agaggttgtg acagaagtga tcaacttcaa aaaataagaa
   121801 aggatttttc gaaaattgct tcttaaattt ttgtggaatt ttggcttatt tttcgaagaa
   121861 gcaacttctg gaacaacgta tattagatat cagaggttgt gaaaaagtcg cttagttttg
   121921 agtaacaagc caaggcgctg atttcacaac ctctgtctat ctatccatct attcggtaag
   121981 attcatgcat gacgtcttct ttatttagta tgtagagccc tttttcttct gaccattcaa
   122041 cataaatcag ctgttttaca tctgcatagc cttctttctt caagttctcc ataagccatg
   122101 cttcagtcaa ttgattggac tgaagcactt tatgctgaat ttgcccttca tctacaagca
   122161 ggatcgataa agctttgtct tcatctgatt ttttcaatac actcatttga ccggcattct
   122221 ctaggataac atgtttggca ttttcaagaa aaaagcattc ttgctgtctt aagattgctc
   122281 gcaactgctc catctcgata tggttatttg tcaactctgt catgttgatg acgccgtctt
   122341 tgattagaac agatggctcg cctttgaccc aacgattgac cttttcattt ttttggacga
   122401 tacgttcgat accataaatc attactgccc aaagcgcaat ggcaaatagg acatgcccta
   122461 catggacatt gtcatcatag gttgattctt ctaagatccc acctaaaaca agcgtataga
   122521 ctaaatcaaa cggtgtgatt tctgacatgg atttcttccc aagcaaacgt accactaata
   122581 ataaaccgat caacccgaac accagtttca ttgtaattga aaaaatcatt ttttctcccc
   122641 ctaactatct gttaattaaa ttatatatgc tttctcacga acacgcatgg aatatacaag
   122701 gaagaaatgt atccttttac taaaaaaagg actgtgacac tgtagtgacc cccaaaagtt
   122761 agactttttt ggagtggaga aatccactcc ttttttttat gctctaaaat gatattttta
   122821 cacaaccgtt acggttgttt tacgaaattg gacgagactt tgccagttta atttctgttt
   122881 tatccgttca ttattgtagt aatagatata gctatcgatg gctgatttta attcctcgaa
   122941 acagttataa actttcccgt gaaaaatctc ttgttttaat aagccaaaaa aattctccat
   123001 aagtgaatta tctaagcagt tccctttccg agacatgctt tgaaagattt tgtactcctt
   123061 caatttgttt ctataagctt tcatttgata cgcccaacct tgatctgagt gaaacgtacg
   123121 acgataggga caatcgttag tggtctggat agcttcctcc aaaccttcca ttaccgctaa
   123181 tgcattgggc ttttcagaga tacgatagga taaaatctca ctattgaaca tatccataaa
   123241 aggatctaga tacaatttct tttgacggat aatgcctttg gcatccactt catggtattt
   123301 aaattcagtt gtatccgtcg tgattttctg atggcagata ctggtgtaga aacgacgatg
   123361 gatccgattt ttggctactg ctccaacttt tcctcgataa gaattgtagc gacgtgattt
   123421 acgcgtgtat gccgttactt ttattcctag cttcttgatc aagcgctgaa ctttcttttt
   123481 attgatagag aaaccgcggt ttcttagttc attggtcatc cgtaaacagc cataatcctt
   123541 gtgcttctcc cgaattttaa gcatttccgc ttcaatctct tgatctggat ttttacggtc
   123601 caatcgcctt tgccatccaa ataatcatga acgatcttta atttaagttc aaaagtatat
   123661 ttaaccataa aaaataccga cctccaaaag ttagattttt tggtctaact tttgggggtc
   123721 ggtacacaaa tcgtgtcaca gtcccttttt tgaaaataaa cggtgttcaa aagcttgcat
   123781 ctgcggtaat aagtccagcc aagttaaaaa cataagaagc tgtttttact tggctgttct
   123841 tattacttga tgcaaggcag ctttttcaca acctcttttc aaatatttcg ttttcttatt
   123901 ctacaaatgg ttcttctcct aacgcttgtt gagcggctag attcaacatg ctccattgtc
   123961 ggtcaaagcc tggctggaag aagaagtcag cttctgctag ttcttctaaa gtcagtttgt
   124021 tttggatcgc tagtgccaat acatttcctt gacctgtaac atcataggta gataatactg
   124081 ctcctcctag caattgatgg gtcattggat ccgagaataa ttggatggac acttttggat
   124141 ttccttgttc ttctggtaca tattttggtc gtaacgtatc ttcataataa gacactcgta
   124201 catctactcc tgcttttgct gctgtaaagc tattcaatcc gcttgctgca aaatgatagt
   124261 caaagacact taatgcagag gaacctacga ctccgccgaa cggtttgttt ggtacttctt
   124321 caaaaagatg ttttactaca taacgtgctt ctctacgtgc aacagtcgct aaagcgatcg
   124381 gcattttttt gcgtgctggg atagaataag caagtgtagc atctcctact gcatacacat
   124441 ctggaagatt cgtttgcaag tattcatttg tttggatcca gccacgttca tctaagtcga
   124501 cgatcccttt taaccattct gtatttgcct tcacaccggc agcttgaatg actagatctg
   124561 ctgggatttc tttttcactt gttttgattg cctcaacttt tccgttacca gtaaaagctt
   124621 cgatttttgc atttgtcaaa acttcaatac cgttttcatt taggtgttgt tctaaaatat
   124681 ctgtcatctc agcatctaaa taagtgccta aaggtctatc gatcacatca agcaatacga
   124741 cttctttccc agcttttcgg cttgcttctg ctgcttcgat cccaatgtaa cccgcaccta
   124801 cgacagcgat ttttttaata gccggatcat ttaatttttc tttgattttg gttgcccaat
   124861 tgtatccacg catcaagtag acattttcta gatctgctcc tggtactggc agattgtttg
   124921 gtttgacacc agaactcaaa atcaatttgt cataaggata ttcttttgtt tcgttatctg
   124981 atacgctagt aaccgttact gtttttttat cggcatcgat cgtttttact tcgtgattat
   125041 ttaaaatatg aacattggat tgcggaaagt tttctggtct gaaattacgt acatcattta
   125101 catctgttac cttgtcttct aaatacagct ccataccaca tgacatgaag gaaatatagt
   125161 ctcctgcttc aaatagcgtg atatctacat tttcaccgta tcgtgtcaat agttccaaga
   125221 ttgattgatg ccctccatga gatgcaccta caatgacaac tttgattttt tccattgatg
   125281 aaacctcctt gaatattctt ttaaaatcat tctaaacaat ttaaacttaa cattacatta
   125341 gttatgaatc aaaagaaacg cgttcatttg aactaaattt aaaaaacaat cgttaatttt
   125401 gcagaatata ccgcaaaatt aacgattgtt tttttgataa aatctatgaa tcactgttct
   125461 gttaaaaagt ctttgattcg tttgcaggcc tcatgtaatt tttccatgct gctagcataa
   125521 gaaatccgga tataaccttc tccttctggg ccaaatgcaa ttcctgggat acacgcaact
   125581 tttgcctgtt ccgctaattc tacacaaaac tgccaagagt cagtttgaat ggcagctggg
   125641 agtttgcaaa acaagtaaaa tgcaccgttt ggctgggtca cttcaaatcc taaaggcgcc
   125701 aattgctgga ccagatagtc tcttcgtgtt tgatattgct ctttcatatt ctcgctatct
   125761 ttcaccccat ttattagcgc ttcagctgca gctttttgcg acatcgttgt agcggcagtc
   125821 accagatatt gatggacttt aattagttcg tcaataaggg ctttttgagc aaaaataaag
   125881 cccactcgcc aaccagtcat cgcatgtgac ttggataacc cgcttatcac gattgtttgt
   125941 tctggaagat aagtagctat ggacatatgc gttccactat aagtcaattc agcatatact
   126001 tcatcactta taacaaatac cggatatttt tttaaaacct cagcgattgc tttcaattgt
   126061 tttgcagaca atgtcgtccc agtaggattg ttaggatagt ttaaaatgac tgctttgaca
   126121 gctgatccat attgttcaaa tgctcgttca aattgttccg gctgacagac aaaccctgta
   126181 tcagaagtat ctatcgggat caattcagca ccagctagtt ccactaatgg ctgatatcct
   126241 gaataagcag gcgctggaat aagaaccttg tctccttctt ccaaaacaga taacaacgca
   126301 gaggcaatcg cttccgttgc accaactgtc gtcaaaactt ccgtttgcgg atcataagtt
   126361 aatccataac gctgttgctg aaacatacaa gccgcttccc gcagttcctc taatcctctc
   126421 attccggtat agtgagaaaa gtcttcttca atcgctgcta ttccggcttg tttgacatgt
   126481 ttaggagttg gaaaatccgg ttctcccagg gtgagtttga tcacatctgg tatcgacgat
   126541 atttgctgat cgaattgtcg tatttttgat acttctattc tagaaagcct gggactaaat
   126601 cgattggata aattcatcat tatatactcg ctcctctttt gatctgctat cgatttttac
   126661 aagaagattt tctgtaaaaa gaatcgtttt gtaccattct acaccatttt ctaaaacatc
   126721 catatcaaaa tcgaacgtcg gatcatgtaa agcaggggta tcaccgacac ctaaaaagaa
   126781 aaatacacat ggatattgtt gcgtatatat gccaaaatct tcggcttgaa gaactggagc
   126841 atctaattca tgtagtttgt ttgaatctaa cagtgctgca tataagcctc tatggttgat
   126901 tacagctgga tagccgtcat tatagtgaaa agaaatagta gctgtagagt gaaactgttc
   126961 tgctaaatgg tctaatcccc tcttcaaata attttgcata tctgaactgt aagaacggat
   127021 acttccagat acaataactt ctccagctaa aacatttcgg atcgttccac cttggatttg
   127081 gccaaatttc attagatgat tccactctgc cggtaattgc cggtcaaaat cataaacatt
   127141 cttcaaaaat cgtacagctg cctccagact atcgattcct ttttcactag aagcaatatg
   127201 tgcagactgg cctttaatga taatgtctgt ttcactgctt tgtgccatca aaggtcctgg
   127261 tcgagagaaa acttctccct tagctagtcc aggccataga tgaaagccaa atattgcttg
   127321 tacttcatat ttatccaaca atcctgactg aataacgctt tgtgcgccac cggaaatttc
   127381 ttctgatggc tgatagatca gtactacatt ataaataaga tcctcaatgt gtttagttat
   127441 aaagtcagtc aaccctaaaa gcatcgccat atgtccgtca tgaccacatg catgcatata
   127501 cccttcatgc ttagaagcaa aagagagatt cgtttcttct ttgactggca gtgcatcgat
   127561 atctgttcga aaagcaatcg tttcttcttg ctgattatca aaataaagga gtagtcctgt
   127621 ttcgccgatt tcatggataa cggccccgct gttttttact tgttcatata aatatttttt
   127681 tgtcttgaat tcatgaaatc cgatttcagg aatttgatgg agtgccattc gatattcttt
   127741 cagcatccgt attcaccatc ccttcataga tacccttcac tactgtttca tattggttat
   127801 tcggtacacc gatgatcaga ttcaactcct gtgctccttg tgataagatc gatgtgcgaa
   127861 tttctaattt gttcaatatc gataacactt ttccagataa accgatcaat tctttatgtg
   127921 gtccgccaac gacagagatc aaagctaagt cttcaatcac gacgatttct tccacgccaa
   127981 gtgtttcttt taattctttc gtgatgagaa ataatttatc ggcaatcgct tctgctgaga
   128041 cgatcactcc gatattgtcg atccctgaag gaatatgttc gattgatatc tcatgtttag
   128101 caaaaatgct cattgctttc cagataaacc cgatttcatc ggacatatgt cgtttaaata
   128161 aagtgatgga aagaaaatcc ttgcgtccag ctattcctgt cagtccattt tccttttcta
   128221 tttcgtgatt cgatattttt gtcccttgag cgaaaggatc attggtattt tttatttgga
   128281 tggggatatc agcctcttga actgggaaaa cagctgcttc atgaagaacg ttagccccca
   128341 tataagccat ctctctcagt tctctaaaag agatttcctc gatgatttta ggatgatcga
   128401 tgattcgcgg atcagccatc atgattcctg aaacatccgt ccaattctca taactttccg
   128461 cttgcaacat cttcgccagt atcgcgccgg taatgtcgct tcccccacgg cccaataatt
   128521 tttcttttcc tgcagggttc gccccgtaaa accctggaac aaccattttc gaatatcttt
   128581 taaatgcttt tgtgatttcc tgtgctgttt tttcctgatc gattttccca tcatagtcaa
   128641 agaaaatcag gtcttttgcg tcaataaact ggtaaccaag atactcagcc atcagttgag
   128701 cagtcagata ttcacctcta cttactaaat aatcttcagt tatcttttcg tcttccagtt
   128761 gtttctgtat gcgtgctagt tcatcttcaa taggtaactg cagggcaaga acatctctta
   128821 cttgaatgaa acgatcacaa atccttttcc aaaggggtgt ccaatcaaca tgatgctgaa
   128881 ggtaagcata aatcaaataa agtaagtctg ttactttgtc atcatctgac gtacgtttgc
   128941 ctaaagcaga aacaacgatc acttggcgat tgggatctga aagaacaatt gtacggactt
   129001 ttttgaattg ctcttcatga gacatcgatg ttccgccgaa tttcgctact ttcagcgtat
   129061 tactcatctt gccacctccg ctattttctg cattaaagct gcagcaatct gtacggcatt
   129121 cgcagcggct cctttgcgta tgttatcggc agtcgtatag aacaacaatc cgttctctaa
   129181 agaagtgtct tttctgatcc tcccaacata aaccatatct gttcctctag caagaatgct
   129241 cgtcggatat ttatgtgctg ctagatcatc ttctaattga atccctggaa actggctgag
   129301 acactctcta atttcttccg tcgtaaactc tttttgcagt tgaactgcca cagagactcc
   129361 atgtccattt tcgattggca cacgtacgca ggttgctgat actggcaaag caggctgatg
   129421 cagaatctta cgggtctcat ttatcatttt ctgttcttct tttgtatacc cattttccaa
   129481 aggctgatcg atttccggaa tcaccgtttg gctaatatta taaggataca aaactggttc
   129541 ctcgtcattt tgcgtacgat gaagatcttc aatgcctttt tgcccggaac cagaaactgc
   129601 ttgataggtc gaataattga ctcgctggat accaaaggct tcttgtaaag ctttaagcgg
   129661 aagtaccgct tgaatggttg aacaatttgg atttgcaatc agccgattca atgtatagtc
   129721 ttccagattg acctctggaa cgattaatgg aatatccgaa tcttcccgcc atgctgagga
   129781 attatctatg acaaatagtc cctgacttcg tgcgattggc gcaaactctt tggatacaga
   129841 agcacctgca gaaaatagcg ctaaatcata tccttcaaat gaagtttctg tcaattcctg
   129901 tacagtgtgt ttctttttct tgaatacaca aactttaccg gctgaacgtt ttgaagctaa
   129961 taatttcaat cgtcctactg gaaaatcata ttcttctaac actttgagca tcgtttggcc
   130021 gactaatccg gttgccccca caatacaggt atctatttcg cgcatttttc tccatctcct
   130081 ctataattcg cgtaacgcag caatcaatgc tgtattttct tttgtctgat catcacttat
   130141 ttttaataca cgtgcaggta ttccaccgac aacagttcct gctgccacat cttctaaaac
   130201 cactgctcct gctgccacga ctgcatcttt tccaatatgg acaccttcaa caatcactgc
   130261 attcgcacct accagtacgc cgtcttctac gataaccggt ttggccgatg ctggttcgat
   130321 cacacctgct aagacagctc ctgcaccaat atggcagttt ttgcccactg tcgctcgtcc
   130381 acctaagaca gcacccatat caatcatcgt gttttcaccg attactgcac caatattgat
   130441 aatcgctccc atcatgatca cggcattgtt gccgattgac acttgatctc tgataatagc
   130501 acctggttcg atacgagcat taattttttt aatatctagc aaaggaactg cgctgtatct
   130561 tgcagcagtt tcgatttcga tttcaatgat tttttctgat tcagcttcta aaaccggagc
   130621 aatcgtctca tagtcaccaa aaacaacgaa gctgcttcct tcaccaaaaa ctttactttc
   130681 tttaaattcg attggctcgg ttacattcag atagactttc acaggcgtct ttttagatgc
   130741 cgtttgaatg tagcggatga tttcttgagc ttccacgttt tttacacccc tttgtccatt
   130801 aataaatctt ctaatttgta ataacctggt gactgatctt tcaaccagtc cgctgcttct
   130861 actgcgcctg cagcaaagat tcgattagaa aaagattcat gtttgatcgt aaatatttca
   130921 tcagtagcag caaacaatac atcatgttca ccaggtaaag aacctgcacg aatactgtgt
   130981 acaccaattt ggttttcttc tctttttttc ccttgccagt tgtatacggg ctgcagcttt
   131041 tgcacttctt ggattgtttg aagcagcata tttgcagtac cagatggtgc atctttttta
   131101 cgactatgat gtttttcaat cagttcgatc tgccagcctt gcaacattgc agctgcttgc
   131161 ttgattagtt gattcatcac catgatgccg aacgaaaaat tagcactata catcacaggt
   131221 acatgtttgg catgttcttt tatttcttgg aactgtgatt gtgtataacc tgtcgtgcca
   131281 atgactaacg gaagttgata agacaagcta tacgaaagga ttttctctaa attatctgga
   131341 tgagaaaaat caataagcag ttctggcagt tccgtaaaag caagcgtagt tgcttcttta
   131401 ggtgccgtcc gtaaaagaag gaccgtatct cctctttctt gtgcaacttc ttcgactcta
   131461 tttcccatct gtccactgcc aatcagtccg attttcattt ttcaaccgtc ctttctttta
   131521 acaaaagctg agctaattgt ttctttttct cttttgaaag agaaactaaa ggcaggcgta
   131581 gaggtccgga aggtaagtct aataatgaca tggctgcttt gacaggaata ggattggtct
   131641 cactgaacaa ggcatggatc agttcaagtg catttaattg cttttctttt gcttgctgcc
   131701 atcttccgtc ctgcgtatct tttactaatt catggactat tttaggttgg atattcgccc
   131761 atacacttat tacaccgctt cctcctacac tcattactgg taggatcaaa tcatcatttc
   131821 cactgtaaag gaagaattct tctccaatca accgagcggc atccatcaca taagccatat
   131881 ctcctgaggc ttctttcaaa ccaatgatat taggatgttc tgctaaattt actaatacat
   131941 ggattggaat cgacatgcct gttctagaag gaacattata caaaataagc ggaatcggtg
   132001 aggcttctgc aattgctgta aaatgagcag ctagtcctgc atcacttgtt ttgttgtagt
   132061 aaggggtgat gaccaaaagt gcgtctgccc ccaaagaagc aaaatgcttc gctttttcaa
   132121 tcgtttcttt cgtattattc gttccagctc ctgcaatcac cggcacacgg ccagccactt
   132181 tctttactgt cagttgaagg atctgctcct cctcagattg tgtgagcgta gaagattctc
   132241 ctgttgtacc taaaactaat aatccgtctg tttgttcatc taaatggaat tggatcaatt
   132301 tttccaaacc agcataatct actgatccct cttcattcat cggcgtgatc agcgccacga
   132361 tcgaaccttt tatcatcttc attcctccaa tattcttgtc cattcatgaa ctgctgggcc
   132421 agccatttgt atcgcatcct caccagagat catcaagtct ccttgttcca agtgaacaac
   132481 tacctgatct gctgaaattt tcccagtttc cttagcaacc acataagagg cacagcaacc
   132541 tgtaccgcaa gcaagtgtcc aacctactcc tctttcatag gtacggacga tcaattcttg
   132601 ttcattgact acttctacaa agttgacatt ggttttttct ttgaacaaag gatgatgaca
   132661 gatcagttca cctctttttc tccagacttc ctcacgcgca ttttcaacaa aaacaacggt
   132721 atgaatcgtt cctaaaaata aactagtgat cgttactttt tcaccattga tctctatttc
   132781 ctggtttttt attggataag tttgattagc tttgattttt tccggagaat catctggcac
   132841 tcccatatct acgctgcaat aaaaaggtga gggatccaac accgtaattt ttcttgtgcc
   132901 tgctaatgtc tctacgttga attcctgttc attcatcatg ttctgatcat ttacgtatcg
   132961 agcaaaacag cgaatgccat ttccgcacat cggcgcgcgg ctgccatctt tgttgtaata
   133021 gatcatttcc aacggatcga tttttacggc gatcaatccg tctgtatcat atttttcttt
   133081 tgtgcataaa gaagcggcta attgactata atctgtgtct tctgcgtaat ctaataagat
   133141 aaaatcattt ccgcagccat tatatttatg aaggatcata ggaaacttcc ccccttagta
   133201 gatcagaaaa tgcttgtctg cgaacaatca gtcttgattg gccattattg acaaaaacaa
   133261 ctgctggtcg tgtcgctcga ttgtagttgc tgctcatcga gtatccataa gctcccgtgg
   133321 aataaacagc taaaagatca cccgattctg ctttcggcaa ataagcttct ttaattacca
   133381 catcgcctga ttcacacatt tttcctgcaa tcgtcacttt ctctgttttt tcttccgaca
   133441 gttttgctgc taaatcacaa tcgtattctg cctgatacag agctggacgg atattatctg
   133501 tcatcccgcc atctacaaag taatattttt tatgtggtgt ctttttgatg aaaccaatcg
   133561 tgtatagtgt tgtaccagct tctccaacaa tacttctacc cggttcaatc agtaattgac
   133621 gaatggtcag ttttcgtttt tccaaagctt cttccgtata ttcaatcagt ttttttagtg
   133681 cctcttcgac tgggattggc tgatcatttt gtgtataacg aatcccaaac cctccgccaa
   133741 gattcaagga aagaggttgg tcaaaatcgg ttaagtaatt cgtcaatttg tcgatttcag
   133801 ctaaccaagc agtaacatca aaaatttgtg acccgatatg agcatgaaat ccttctaact
   133861 ctagatagct tctttctttt atcaactgaa gggcttgttg gcactcttta ctttcatagc
   133921 tcatgccgaa ttttgaatca atatgcgcag tgacgatata ttcatgagta tgtgcttcta
   133981 ctccgacatt caaccgaagc atgatacaga ttttttttaa atagcgttgg cttaattctg
   134041 ctaataattc aacttccatc aaattatcgg caacaatatg caacaaatca ttttcaagtg
   134101 catagatcag ttcctctggc gtcttgttgt taccatggaa gtagatagta tctctaggga
   134161 aatcagcttg caaagcggta tagatttccc caccactgac aacatctagc ccgaatccat
   134221 attcacgaac taaatgcagc atctcaatcg tttggaatgc tttagaggcg taaagtactt
   134281 ttgtatcaaa acgtttcgat acaaagcctc gcttgaatga cagcatcgtt tgtctcatct
   134341 tttcttcatc atacacatac agaggtgtct tatacttttc tgccaatgtg cttgctgtga
   134401 ctccgccaat tatcaattct gtcatttttt cattcctctt ttcacttttt ttccgttttt
   134461 attggaattt catttgataa agatttgaat tttattggaa taatattaaa caaaattttc
   134521 tgaattgtct agtatatttc gaaatatttt tttaaaaata agaataaaaa tggttataaa
   134581 aacaaaatac ccgaactatt agaagctatt tatacacaaa aacataaatt caacactatt
   134641 tagtgatgaa aaaatatttt cgcttcaata tagttcggaa tagttcggat attttcaatt
   134701 ttatgaatca tttcaatttc ttcataaata agtgcagttt cttctctctc tagcttttgc
   134761 cattcatctt tcaaaatata aataaaatca aatacttttt tatttttcaa tttgctgatt
   134821 ccacaaaaaa cctcttgaaa ggcagatccg atgatctgcc tttcaagagg tcaagctctg
   134881 ttttcaaatt cttatcaatc cgttagcgaa ttattttgac gcacgtttta cataagaacc
   134941 ttctgctgta ttgatttcca acaattcatc tgtttcgatg aagtcaggaa cattgactac
   135001 taagccagtt tccattgtcg ctggtttacc tgaaccagtg actgttgcac ctttgatgga
   135061 aggttgtgtt tccacaacac gtaatacgac agttgttggt aattgaacgc cgatgacttc
   135121 gctaccgaag aattggattt ttacttccat gttttctagg atatatttca tttcttcttc
   135181 tactgtttct acaggaattt catattgctc atatgtttcc aaatccatga agaaagctgt
   135241 atcatccatc gtgtacaaat attgtacagg ttttgtgtcg atgtgtgctt tttcaaattt
   135301 ttcttctggt ctgaacgttg tgtcgtatgt tgcacctgaa cggacatctt tcagtttcat
   135361 acgcataact gtatttcctt taccaggttt atggtggctt gcatccagaa ctttaatcag
   135421 tttgccgtct tgtacgaaag tcataccggc tcttaaatca cttgctgaga tcattatttt
   135481 tgctccttct tttctttatc ataatcaact ttattgtatc agacaaccgg ccagaaaact
   135541 agagtattct ctatctttta aggtctcatg cctatttgtc agaaaaataa acacgggtaa
   135601 acgatgctat cgaaatattt ttttctttca atcctttgac ttttattttt tttcatgcta
   135661 tcgttaataa aaattttact tggagggata cacatgacag tcagcaacca aaaacaattg
   135721 aatcgttgct gttgtatggt gcataaaagc agcatactat ttgtcatgtc tattaattgc
   135781 ccttcataga atgagtacca ggtaacttat ctttttatct actcaatttt tctctatgtc
   135841 tttcaaggag ctgatttaat agtcagctcc tttttttatt atcttttttt aggaggccca
   135901 tatgattatc tcgacaatta cagaagctat tggttccaca ccgctttatc gctttgacaa
   135961 tcagcactat tctatgccta aaggttctgc tatttatgca aaactagaat atttaaatcc
   136021 tggaggaagt atcaaagata gattgggcag ttatttgatc aaagaaggat ttgcccaagg
   136081 aaaaatcaat gaaaaaacga cgatcatcga accaactgcc ggaaatacag gaattgggat
   136141 cgctctggcc gcactcacat acaaattaag aacggttttt gttgttccag agaagtttag
   136201 cttagaaaaa caacaattga tgaaagcatt gggagcaaag atcatccatt ctcctagtga
   136261 gcaaggaatc atcggtgcca tcagcaaaag taaaaaactt gcagaggaga tatcaaacag
   136321 ctatctgcct cttcaatttg aaaataaaga taatcctgct gcttactatc atacgttagg
   136381 gccagaaatc tttcatgaaa tcaaagaaaa tatccatagt tttgtagcag gaattgggag
   136441 tggtggaacc tttgctggaa cttctacctt tttgaaagaa aaatatcccg acattcgaat
   136501 aatcggtgta gaaccagagg gctctgtgtt aaatggtggt gatccagccc ctcacgaaat
   136561 tgagggtatc ggtgtagaat tcattccgcc gtttctttct cccctttcaa tcaatcagat
   136621 cgagacaatc tctgatgtag aagggtttaa ctatactagg cagttagcac gagaacaagg
   136681 actattagtt ggaagttcga gtggtgcggc ttttgcagca gcattaagag aaattcgtcg
   136741 tttaccacct ggtcatcgtg tcgttacgat ttttccagac gcagcagacc gctatttatc
   136801 aaaaaacatt tacttatagg aggaaagaaa catgcacatt caaacaaaat tgatccacgg
   136861 aggcatcagt gaagatccca caacaggagc tgtcagtgta cctatttatc aaacatccac
   136921 ttatcggcaa gatggcgtcg gccagcctaa gcaatatgaa tattcgagat ctggtaatcc
   136981 tactcgtttt gcattggaag aactgattgc tgatttggaa ggcggtgttc gaggattcgc
   137041 tttttcttct ggtctttctg ggattcatgc cgttttttct ctttttcaag ctggcgatca
   137101 tatcttatta ggagatgatg tctatggagg aacattccgt ctatttgaca aagttcttac
   137161 taaaaatggt ctcgagtaca cgatcataga tacgagtaat cttgataaaa tagaacaatc
   137221 catcaaaccc aatacaaaag cactttatct tgaaacacct agcaatccgc ttctaaagat
   137281 tactgattta gaaaaaagtg ccactctggc tcatcaacat ggattgatag ttattgctga
   137341 caatacattt gctactcctt attttcaaag acctttagat ctcggttctg atatcgttgt
   137401 ccatagcggt accaaatatc taggcggaca cagcgatgta gtagctggtt tagtgacttc
   137461 taaccataaa gatctagccg atcagatcgg attttaccaa aatgctatcg gagccgtact
   137521 tggtccccaa gatagttggt tacttcagcg cggaatcaag acactaagtg ttcgtatgga
   137581 ggaacatcaa aaaaatgctt ttgtggtagc tgattttcta ttttctcatc cagcagtaga
   137641 aaaggtctac tatccaggat taccccatca tgaactccat ggagttgcta agcagcagat
   137701 gagcggcttt agcggaatga tttcttttac tttaaaaaat gaagaaactg ctattccatt
   137761 tgttgaatca ctccaactat ttactttagc agaaagttta ggtggcgtag aaagtttagt
   137821 ggaaattcct tctgtcatga ctcatgcgtc tattccaaaa gaaaaacgag aagaggctgg
   137881 cataaaggac ggcttgatcc gtctttctgt aggaattgag tatggtcagg atctcataaa
   137941 cgatttagct caggcatttg acagaatcaa gaactagaag tcccaataaa cgacttagca
   138001 gaaaaatcta aaaaatattt cagattgcta caccttggaa acgataagtg ttagaatcaa
   138061 gtagaaagac gtttttgtaa atttcactaa ataattcttt agtgaaaagc atcaaaacga
   138121 atgaacaaac agataggagt cttacaaatg agaatgaatg tcgaaagttt taatcttgac
   138181 catacaaaag tcaaagcacc ttatgtacgt gtagctgatc gaaaaacggg tgcgcatggc
   138241 gatgtcatca ttaaatacga cgtccgcttt aaacaaccaa ataaagaaca catggacatg
   138301 ccaagtctac attcacttga gcacttgact gccgaactaa tccgcaatca cgcagattac
   138361 atcgtagact ggtctccaat gggatgccaa acaggctttt acttgactgt attgaatcat
   138421 gaaagctacg aagacatttt agatgttctt gaagcaacaa tgaaagatgt tcttgaagct
   138481 actgaagtac ctgcaagcaa tgaaacacaa tgtggctggg ctgccagcca tacactagaa
   138541 ggtgcacaag ctttggctcg tgaattttta gcaaaacgcg atgaatggtc tgaagtagaa
   138601 gcatagtttc taaaagaacg taaagatgag aagcaatata gctatcttat cttcgtattt
   138661 tattaaatat ttattgtctg aaaagagttc taaacgggaa aacaaatagc tagttttcag
   138721 tttagcgctc tttt
//
LOCUS       DAXLPQ010000002       129101 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.002, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000002 DAXLPQ010000000
VERSION     DAXLPQ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 129101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 129101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..129101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.002"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            352..1041
                     /locus_tag="ACF3UO_000127"
     CDS             352..1041
                     /locus_tag="ACF3UO_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3656188.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="ACF3UO_000128"
     CDS             1028..2236
                     /locus_tag="ACF3UO_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFD3656189.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="ACF3UO_000129"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="ACF3UO_000129"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFD3656190.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="ACF3UO_000130"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="ACF3UO_000130"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFD3656191.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="ACF3UO_000131"
     CDS             complement(6339..7034)
                     /locus_tag="ACF3UO_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFD3656192.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="ACF3UO_000132"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="ACF3UO_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFD3656193.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="ACF3UO_000133"
     CDS             complement(8233..8424)
                     /locus_tag="ACF3UO_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFD3656194.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="ACF3UO_000134"
     CDS             complement(8445..9335)
                     /locus_tag="ACF3UO_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFD3656195.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="ACF3UO_000135"
     CDS             complement(9322..10089)
                     /locus_tag="ACF3UO_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3656196.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="ACF3UO_000136"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="ACF3UO_000136"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFD3656197.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="ACF3UO_000137"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="ACF3UO_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFD3656198.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="ACF3UO_000138"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="ACF3UO_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFD3656199.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14660..15043
                     /locus_tag="ACF3UO_000139"
     CDS             14660..15043
                     /locus_tag="ACF3UO_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656200.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15211..15969)
                     /gene="jag"
                     /locus_tag="ACF3UO_000140"
     CDS             complement(15211..15969)
                     /gene="jag"
                     /locus_tag="ACF3UO_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFD3656201.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="ACF3UO_000141"
     CDS             complement(15987..16805)
                     /locus_tag="ACF3UO_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFD3656202.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="ACF3UO_000142"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="ACF3UO_000142"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFD3656203.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="ACF3UO_000143"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="ACF3UO_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFD3656204.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17933..19267
                     /gene="dnaA"
                     /locus_tag="ACF3UO_000144"
     CDS             17933..19267
                     /gene="dnaA"
                     /locus_tag="ACF3UO_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFD3656205.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19465..20595
                     /gene="dnaN"
                     /locus_tag="ACF3UO_000145"
     CDS             19465..20595
                     /gene="dnaN"
                     /locus_tag="ACF3UO_000145"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFD3656206.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20824..21066
                     /gene="yaaA"
                     /locus_tag="ACF3UO_000146"
     CDS             20824..21066
                     /gene="yaaA"
                     /locus_tag="ACF3UO_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFD3656207.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21053..22177
                     /gene="recF"
                     /locus_tag="ACF3UO_000147"
     CDS             21053..22177
                     /gene="recF"
                     /locus_tag="ACF3UO_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFD3656208.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22174..24120
                     /gene="gyrB"
                     /locus_tag="ACF3UO_000148"
     CDS             22174..24120
                     /gene="gyrB"
                     /locus_tag="ACF3UO_000148"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFD3656209.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24140..26611
                     /gene="gyrA"
                     /locus_tag="ACF3UO_000149"
     CDS             24140..26611
                     /gene="gyrA"
                     /locus_tag="ACF3UO_000149"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFD3656210.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26847..27146
                     /gene="rpsF"
                     /locus_tag="ACF3UO_000150"
     CDS             26847..27146
                     /gene="rpsF"
                     /locus_tag="ACF3UO_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFD3656211.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27196..27708
                     /gene="ssb"
                     /locus_tag="ACF3UO_000151"
     CDS             27196..27708
                     /gene="ssb"
                     /locus_tag="ACF3UO_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD3656212.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27734..27970
                     /gene="rpsR"
                     /locus_tag="ACF3UO_000152"
     CDS             27734..27970
                     /gene="rpsR"
                     /locus_tag="ACF3UO_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFD3656213.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28113..30086
                     /locus_tag="ACF3UO_000153"
     CDS             28113..30086
                     /locus_tag="ACF3UO_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFD3656214.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30092..30544
                     /gene="rplI"
                     /locus_tag="ACF3UO_000154"
     CDS             30092..30544
                     /gene="rplI"
                     /locus_tag="ACF3UO_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFD3656215.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30818..32185
                     /gene="dnaB"
                     /locus_tag="ACF3UO_000155"
     CDS             30818..32185
                     /gene="dnaB"
                     /locus_tag="ACF3UO_000155"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFD3656216.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            32965..34257
                     /locus_tag="ACF3UO_000156"
     CDS             32965..34257
                     /locus_tag="ACF3UO_000156"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFD3656217.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35044..35907
                     /locus_tag="ACF3UO_000157"
     CDS             35044..35907
                     /locus_tag="ACF3UO_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3656218.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36036..37658)
                     /locus_tag="ACF3UO_000158"
     CDS             complement(36036..37658)
                     /locus_tag="ACF3UO_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3656219.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            37907..38428
                     /locus_tag="ACF3UO_000159"
     CDS             37907..38428
                     /locus_tag="ACF3UO_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFD3656220.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSVLTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38614..40344)
                     /gene="spxB"
                     /locus_tag="ACF3UO_000160"
     CDS             complement(38614..40344)
                     /gene="spxB"
                     /locus_tag="ACF3UO_000160"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFD3656221.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40509..41327
                     /locus_tag="ACF3UO_000161"
     CDS             40509..41327
                     /locus_tag="ACF3UO_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFD3656222.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41430..41627)
                     /locus_tag="ACF3UO_000162"
     CDS             complement(41430..41627)
                     /locus_tag="ACF3UO_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656223.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41796..42374
                     /locus_tag="ACF3UO_000163"
     CDS             41796..42374
                     /locus_tag="ACF3UO_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFD3656224.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42469..42606
                     /locus_tag="ACF3UO_000164"
     CDS             42469..42606
                     /locus_tag="ACF3UO_000164"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656225.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43419..43922)
                     /locus_tag="ACF3UO_000165"
     CDS             complement(43419..43922)
                     /locus_tag="ACF3UO_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3656226.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44281..45306
                     /locus_tag="ACF3UO_000166"
     CDS             44281..45306
                     /locus_tag="ACF3UO_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3656227.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45629..46507
                     /locus_tag="ACF3UO_000167"
     CDS             45629..46507
                     /locus_tag="ACF3UO_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFD3656228.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            46983..47099
                     /locus_tag="ACF3UO_000168"
     CDS             46983..47099
                     /locus_tag="ACF3UO_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFD3656229.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48027..48365
                     /locus_tag="ACF3UO_000169"
     CDS             48027..48365
                     /locus_tag="ACF3UO_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656230.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48459..48689
                     /locus_tag="ACF3UO_000170"
     CDS             48459..48689
                     /locus_tag="ACF3UO_000170"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFD3656231.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49089..49460
                     /locus_tag="ACF3UO_000171"
     CDS             49089..49460
                     /locus_tag="ACF3UO_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFD3656232.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49734..50426)
                     /locus_tag="ACF3UO_000172"
     CDS             complement(49734..50426)
                     /locus_tag="ACF3UO_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3656233.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50429..51214)
                     /locus_tag="ACF3UO_000173"
     CDS             complement(50429..51214)
                     /locus_tag="ACF3UO_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3656234.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51451..52851
                     /gene="lacG"
                     /locus_tag="ACF3UO_000174"
     CDS             51451..52851
                     /gene="lacG"
                     /locus_tag="ACF3UO_000174"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFD3656235.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            52876..53193
                     /locus_tag="ACF3UO_000175"
     CDS             52876..53193
                     /locus_tag="ACF3UO_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3656236.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53206..54879
                     /locus_tag="ACF3UO_000176"
     CDS             53206..54879
                     /locus_tag="ACF3UO_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFD3656237.1"
                     /translation="MDGIIKQIEKGKAFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            54893..56524
                     /locus_tag="ACF3UO_000177"
     CDS             54893..56524
                     /locus_tag="ACF3UO_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFD3656238.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(57015..58580)
                     /gene="guaA"
                     /locus_tag="ACF3UO_000178"
     CDS             complement(57015..58580)
                     /gene="guaA"
                     /locus_tag="ACF3UO_000178"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFD3656239.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(58639..59562)
                     /gene="coaA"
                     /locus_tag="ACF3UO_000179"
     CDS             complement(58639..59562)
                     /gene="coaA"
                     /locus_tag="ACF3UO_000179"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFD3656240.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            59758..60363
                     /locus_tag="ACF3UO_000180"
     CDS             59758..60363
                     /locus_tag="ACF3UO_000180"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3656241.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            60671..61687
                     /locus_tag="ACF3UO_000181"
     CDS             60671..61687
                     /locus_tag="ACF3UO_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3656242.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            61828..63129
                     /locus_tag="ACF3UO_000182"
     CDS             61828..63129
                     /locus_tag="ACF3UO_000182"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFD3656243.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            63175..63837
                     /gene="deoC"
                     /locus_tag="ACF3UO_000183"
     CDS             63175..63837
                     /gene="deoC"
                     /locus_tag="ACF3UO_000183"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFD3656244.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            63858..64256
                     /locus_tag="ACF3UO_000184"
     CDS             63858..64256
                     /locus_tag="ACF3UO_000184"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFD3656245.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            64322..65404
                     /locus_tag="ACF3UO_000185"
     CDS             64322..65404
                     /locus_tag="ACF3UO_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3656246.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            65616..67178
                     /locus_tag="ACF3UO_000186"
     CDS             65616..67178
                     /locus_tag="ACF3UO_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656247.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            67171..68304
                     /locus_tag="ACF3UO_000187"
     CDS             67171..68304
                     /locus_tag="ACF3UO_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3656248.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            68304..69260
                     /locus_tag="ACF3UO_000188"
     CDS             68304..69260
                     /locus_tag="ACF3UO_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3656249.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            69359..70525
                     /gene="deoB"
                     /locus_tag="ACF3UO_000189"
     CDS             69359..70525
                     /gene="deoB"
                     /locus_tag="ACF3UO_000189"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFD3656250.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            70549..71367
                     /locus_tag="ACF3UO_000190"
     CDS             70549..71367
                     /locus_tag="ACF3UO_000190"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD3656251.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            71384..72091
                     /gene="deoD"
                     /locus_tag="ACF3UO_000191"
     CDS             71384..72091
                     /gene="deoD"
                     /locus_tag="ACF3UO_000191"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD3656252.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(72389..73075)
                     /gene="gpmA"
                     /locus_tag="ACF3UO_000192"
     CDS             complement(72389..73075)
                     /gene="gpmA"
                     /locus_tag="ACF3UO_000192"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFD3656253.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(73247..73828)
                     /locus_tag="ACF3UO_000193"
     CDS             complement(73247..73828)
                     /locus_tag="ACF3UO_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3656254.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(73961..74644)
                     /gene="rpiA"
                     /locus_tag="ACF3UO_000194"
     CDS             complement(73961..74644)
                     /gene="rpiA"
                     /locus_tag="ACF3UO_000194"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFD3656255.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            74963..75376
                     /gene="rpsL"
                     /locus_tag="ACF3UO_000195"
     CDS             74963..75376
                     /gene="rpsL"
                     /locus_tag="ACF3UO_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFD3656256.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            75460..75930
                     /gene="rpsG"
                     /locus_tag="ACF3UO_000196"
     CDS             75460..75930
                     /gene="rpsG"
                     /locus_tag="ACF3UO_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFD3656257.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            76024..78111
                     /gene="fusA"
                     /locus_tag="ACF3UO_000197"
     CDS             76024..78111
                     /gene="fusA"
                     /locus_tag="ACF3UO_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFD3656258.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            78283..79470
                     /gene="tuf"
                     /locus_tag="ACF3UO_000198"
     CDS             78283..79470
                     /gene="tuf"
                     /locus_tag="ACF3UO_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFD3656259.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            79877..80185
                     /gene="rpsJ"
                     /locus_tag="ACF3UO_000199"
     CDS             79877..80185
                     /gene="rpsJ"
                     /locus_tag="ACF3UO_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFD3656260.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            80216..80845
                     /gene="rplC"
                     /locus_tag="ACF3UO_000200"
     CDS             80216..80845
                     /gene="rplC"
                     /locus_tag="ACF3UO_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFD3656261.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            80873..81496
                     /gene="rplD"
                     /locus_tag="ACF3UO_000201"
     CDS             80873..81496
                     /gene="rplD"
                     /locus_tag="ACF3UO_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFD3656262.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            81496..81786
                     /gene="rplW"
                     /locus_tag="ACF3UO_000202"
     CDS             81496..81786
                     /gene="rplW"
                     /locus_tag="ACF3UO_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFD3656263.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            81825..82658
                     /gene="rplB"
                     /locus_tag="ACF3UO_000203"
     CDS             81825..82658
                     /gene="rplB"
                     /locus_tag="ACF3UO_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFD3656264.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            82701..82979
                     /gene="rpsS"
                     /locus_tag="ACF3UO_000204"
     CDS             82701..82979
                     /gene="rpsS"
                     /locus_tag="ACF3UO_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFD3656265.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            83002..83349
                     /gene="rplV"
                     /locus_tag="ACF3UO_000205"
     CDS             83002..83349
                     /gene="rplV"
                     /locus_tag="ACF3UO_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFD3656266.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            83363..84019
                     /gene="rpsC"
                     /locus_tag="ACF3UO_000206"
     CDS             83363..84019
                     /gene="rpsC"
                     /locus_tag="ACF3UO_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFD3656267.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            84022..84456
                     /gene="rplP"
                     /locus_tag="ACF3UO_000207"
     CDS             84022..84456
                     /gene="rplP"
                     /locus_tag="ACF3UO_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFD3656268.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            84446..84634
                     /gene="rpmC"
                     /locus_tag="ACF3UO_000208"
     CDS             84446..84634
                     /gene="rpmC"
                     /locus_tag="ACF3UO_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFD3656269.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            84659..84925
                     /gene="rpsQ"
                     /locus_tag="ACF3UO_000209"
     CDS             84659..84925
                     /gene="rpsQ"
                     /locus_tag="ACF3UO_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFD3656270.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            84983..85351
                     /gene="rplN"
                     /locus_tag="ACF3UO_000210"
     CDS             84983..85351
                     /gene="rplN"
                     /locus_tag="ACF3UO_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFD3656271.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            85388..85696
                     /gene="rplX"
                     /locus_tag="ACF3UO_000211"
     CDS             85388..85696
                     /gene="rplX"
                     /locus_tag="ACF3UO_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFD3656272.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            85724..86263
                     /gene="rplE"
                     /locus_tag="ACF3UO_000212"
     CDS             85724..86263
                     /gene="rplE"
                     /locus_tag="ACF3UO_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFD3656273.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            86282..86467
                     /locus_tag="ACF3UO_000213"
     CDS             86282..86467
                     /locus_tag="ACF3UO_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFD3656274.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            86503..86901
                     /gene="rpsH"
                     /locus_tag="ACF3UO_000214"
     CDS             86503..86901
                     /gene="rpsH"
                     /locus_tag="ACF3UO_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFD3656275.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            86933..87469
                     /gene="rplF"
                     /locus_tag="ACF3UO_000215"
     CDS             86933..87469
                     /gene="rplF"
                     /locus_tag="ACF3UO_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFD3656276.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            87630..87986
                     /gene="rplR"
                     /locus_tag="ACF3UO_000216"
     CDS             87630..87986
                     /gene="rplR"
                     /locus_tag="ACF3UO_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFD3656277.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            88007..88507
                     /gene="rpsE"
                     /locus_tag="ACF3UO_000217"
     CDS             88007..88507
                     /gene="rpsE"
                     /locus_tag="ACF3UO_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFD3656278.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            88522..88701
                     /gene="rpmD"
                     /locus_tag="ACF3UO_000218"
     CDS             88522..88701
                     /gene="rpmD"
                     /locus_tag="ACF3UO_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFD3656279.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            88745..89185
                     /gene="rplO"
                     /locus_tag="ACF3UO_000219"
     CDS             88745..89185
                     /gene="rplO"
                     /locus_tag="ACF3UO_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFD3656280.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            89185..90480
                     /gene="secY"
                     /locus_tag="ACF3UO_000220"
     CDS             89185..90480
                     /gene="secY"
                     /locus_tag="ACF3UO_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFD3656281.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            90542..91189
                     /locus_tag="ACF3UO_000221"
     CDS             90542..91189
                     /locus_tag="ACF3UO_000221"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFD3656282.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            91380..91598
                     /gene="infA"
                     /locus_tag="ACF3UO_000222"
     CDS             91380..91598
                     /gene="infA"
                     /locus_tag="ACF3UO_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFD3656283.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            91631..91747
                     /gene="rpmJ"
                     /locus_tag="ACF3UO_000223"
     CDS             91631..91747
                     /gene="rpmJ"
                     /locus_tag="ACF3UO_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFD3656284.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            91765..92130
                     /gene="rpsM"
                     /locus_tag="ACF3UO_000224"
     CDS             91765..92130
                     /gene="rpsM"
                     /locus_tag="ACF3UO_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFD3656285.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            92158..92547
                     /gene="rpsK"
                     /locus_tag="ACF3UO_000225"
     CDS             92158..92547
                     /gene="rpsK"
                     /locus_tag="ACF3UO_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFD3656286.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            92627..93565
                     /locus_tag="ACF3UO_000226"
     CDS             92627..93565
                     /locus_tag="ACF3UO_000226"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFD3656287.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            93593..93973
                     /gene="rplQ"
                     /locus_tag="ACF3UO_000227"
     CDS             93593..93973
                     /gene="rplQ"
                     /locus_tag="ACF3UO_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFD3656288.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            94245..95084
                     /locus_tag="ACF3UO_000228"
     CDS             94245..95084
                     /locus_tag="ACF3UO_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3656289.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            95060..95929
                     /locus_tag="ACF3UO_000229"
     CDS             95060..95929
                     /locus_tag="ACF3UO_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3656290.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            95919..96716
                     /locus_tag="ACF3UO_000230"
     CDS             95919..96716
                     /locus_tag="ACF3UO_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFD3656291.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            96919..97665
                     /gene="truA"
                     /locus_tag="ACF3UO_000231"
     CDS             96919..97665
                     /gene="truA"
                     /locus_tag="ACF3UO_000231"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFD3656292.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(98120..100789)
                     /locus_tag="ACF3UO_000232"
     CDS             complement(98120..100789)
                     /locus_tag="ACF3UO_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFD3656293.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(101027..101215)
                     /gene="rpmB"
                     /locus_tag="ACF3UO_000233"
     CDS             complement(101027..101215)
                     /gene="rpmB"
                     /locus_tag="ACF3UO_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFD3656294.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            101485..101847
                     /locus_tag="ACF3UO_000234"
     CDS             101485..101847
                     /locus_tag="ACF3UO_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3656295.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            101899..103581
                     /locus_tag="ACF3UO_000235"
     CDS             101899..103581
                     /locus_tag="ACF3UO_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFD3656296.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            103698..105734
                     /gene="recG"
                     /locus_tag="ACF3UO_000236"
     CDS             103698..105734
                     /gene="recG"
                     /locus_tag="ACF3UO_000236"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFD3656297.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            105783..106784
                     /gene="plsX"
                     /locus_tag="ACF3UO_000237"
     CDS             105783..106784
                     /gene="plsX"
                     /locus_tag="ACF3UO_000237"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFD3656298.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            106906..107148
                     /gene="acpP"
                     /locus_tag="ACF3UO_000238"
     CDS             106906..107148
                     /gene="acpP"
                     /locus_tag="ACF3UO_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFD3656299.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            107416..108420
                     /locus_tag="ACF3UO_000239"
     CDS             107416..108420
                     /locus_tag="ACF3UO_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656300.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            108421..109365
                     /locus_tag="ACF3UO_000240"
     CDS             108421..109365
                     /locus_tag="ACF3UO_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656301.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            109365..110327
                     /gene="opp4B"
                     /locus_tag="ACF3UO_000241"
     CDS             109365..110327
                     /gene="opp4B"
                     /locus_tag="ACF3UO_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFD3656302.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            110354..111268
                     /locus_tag="ACF3UO_000242"
     CDS             110354..111268
                     /locus_tag="ACF3UO_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3656303.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            111294..113075
                     /locus_tag="ACF3UO_000243"
     CDS             111294..113075
                     /locus_tag="ACF3UO_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3656304.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            113423..114109
                     /gene="rnc"
                     /locus_tag="ACF3UO_000244"
     CDS             113423..114109
                     /gene="rnc"
                     /locus_tag="ACF3UO_000244"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFD3656305.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            114129..117710
                     /gene="smc"
                     /locus_tag="ACF3UO_000245"
     CDS             114129..117710
                     /gene="smc"
                     /locus_tag="ACF3UO_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFD3656306.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            117719..118528
                     /locus_tag="ACF3UO_000246"
     CDS             117719..118528
                     /locus_tag="ACF3UO_000246"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3656307.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            118539..119537
                     /gene="ftsY"
                     /locus_tag="ACF3UO_000247"
     CDS             118539..119537
                     /gene="ftsY"
                     /locus_tag="ACF3UO_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFD3656308.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            119724..121991
                     /gene="gshAB"
                     /locus_tag="ACF3UO_000248"
     CDS             119724..121991
                     /gene="gshAB"
                     /locus_tag="ACF3UO_000248"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFD3656309.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(122080..122532)
                     /locus_tag="ACF3UO_000249"
     CDS             complement(122080..122532)
                     /locus_tag="ACF3UO_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFD3656310.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            122682..123632
                     /locus_tag="ACF3UO_000250"
     CDS             122682..123632
                     /locus_tag="ACF3UO_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3656311.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            123625..124584
                     /locus_tag="ACF3UO_000251"
     CDS             123625..124584
                     /locus_tag="ACF3UO_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3656312.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            124581..125336
                     /locus_tag="ACF3UO_000252"
     CDS             124581..125336
                     /locus_tag="ACF3UO_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656313.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            125359..126312
                     /locus_tag="ACF3UO_000253"
     CDS             125359..126312
                     /locus_tag="ACF3UO_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3656314.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(126956..127252)
                     /locus_tag="ACF3UO_000254"
     CDS             complement(126956..127252)
                     /locus_tag="ACF3UO_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFD3656315.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            127607..127963
                     /locus_tag="ACF3UO_000255"
     CDS             127607..127963
                     /locus_tag="ACF3UO_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3656316.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            127973..128872
                     /locus_tag="ACF3UO_000256"
     CDS             127973..128872
                     /locus_tag="ACF3UO_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3656317.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        40931 a        23609 c        26981 g        37580 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggaatcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa aaggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggcgattt cctgtgtatt ccgtctccta actattggta tatctgtatt
    17701 ttttatccac agacgcaaga ggaaatctat tggtttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    17821 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    17881 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    17941 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18001 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18061 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18121 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18181 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18241 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18301 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18361 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18421 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18481 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18541 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18601 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18661 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgccttgttt ctcgctttgc
    18721 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    18781 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    18841 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    18901 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    18961 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19021 ttatcacatc caattgaaag atctcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19081 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19141 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19201 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19261 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19321 aaaagttata cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19381 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19441 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19501 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19561 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19621 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19681 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19741 tttactttag aagttttaga aaataaacaa gtagcgatca cttctggaaa agcgaatttt
    19801 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    19861 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    19921 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    19981 ttattagctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20041 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20101 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20161 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatccaga taccaatcgt
    20221 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20281 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20341 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20401 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20461 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20521 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20581 gtacgtacaa attaacaatg attttcaatg ttcttgaaaa tttaattgaa aagaaataga
    20641 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20701 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    20761 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    20821 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    20881 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    20941 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21001 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21061 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21121 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21181 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21241 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21301 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacagaaaaa
    21361 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21421 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21481 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21541 cttgaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21601 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21661 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21721 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    21781 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    21841 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    21901 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    21961 taaagaagag acaggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22021 tgataatcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22081 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22141 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22201 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22261 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22321 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22381 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22441 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22501 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22561 gttgtaaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22621 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22681 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22741 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    22801 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    22861 ggcgggatca aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    22921 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    22981 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggtgga
    23041 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23101 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23161 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23221 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23281 ttcttgctgg aaaacccaag tgtgggccgg caaattgttg aaaaaggatt actagcttcc
    23341 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23401 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23461 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23521 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23581 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23641 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23701 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    23761 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    23821 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    23881 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    23941 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24001 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24061 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24121 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24181 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24241 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24301 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24361 catgggtaaa taccatcctc atggagacat tgcgatctat gagtcaatgg tacggatggc
    24421 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24481 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24541 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24601 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24661 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24721 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    24781 tggaccagat tttccaacag gtggtttggt tatggggaaa tcaggaatcc gaagagcgta
    24841 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    24901 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    24961 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25021 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25081 cgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25141 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaatcc ttgaaaacta
    25201 tatcgaacat caacgcgaag tcatcacacg acggacggtc tttgaaaaag aaaaagcaga
    25261 agcaagagca cacatcttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25321 tgcgattatc cgcgggtcta aatcagatga cgaggcaaaa gcaacaatga tcgaacggtt
    25381 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25441 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25501 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25561 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25621 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25681 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25741 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    25801 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    25861 tccagaatac gggcgtacag ccaaaggaat cccaatcatc aatttactag gtatcgattc
    25921 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    25981 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26041 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26101 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26161 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggtcagag ggatacgcct
    26221 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaaaatcaag aagtattagt
    26281 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26341 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26401 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26461 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26521 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26581 aacagttgaa gaacaaggat cagaagaata accatcaaga ctaagtgtgt aagctagcaa
    26641 gaataaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26701 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatta
    26761 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    26821 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    26881 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    26941 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27001 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27061 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27121 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27181 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27241 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27301 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27361 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27421 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27481 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27541 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27601 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27661 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27721 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    27781 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    27841 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    27901 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    27961 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28021 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28081 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28141 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28201 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28261 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28321 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28381 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28441 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28501 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28561 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28621 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattagatg
    28681 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28741 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    28801 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    28861 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    28921 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    28981 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29041 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29101 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29161 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29221 tcgttatcaa tgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29281 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29341 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29401 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29461 caagtaaacc tctgctgact tatattgaat cttcagcttc ttcagcttca gagctagttt
    29521 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29581 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29641 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29701 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    29761 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    29821 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    29881 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    29941 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30001 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30061 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30121 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30181 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30241 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30301 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30361 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30421 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30481 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30541 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30601 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30661 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30721 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    30781 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    30841 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    30901 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    30961 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31021 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31081 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31141 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31201 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31261 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31321 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31381 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31441 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31501 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31561 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31621 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31681 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31741 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    31801 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    31861 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    31921 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    31981 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32041 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32101 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32161 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32221 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32281 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32341 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32401 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32461 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32521 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32581 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32641 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32701 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    32761 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    32821 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    32881 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    32941 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33001 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33061 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33121 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33181 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33241 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33301 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33361 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33421 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33481 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33541 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33601 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33661 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33721 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    33781 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    33841 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    33901 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    33961 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34021 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34081 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34141 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34201 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34261 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34321 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34381 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aaaccgtgtc acagtccctt
    34441 tttccgaaca aacggtgttc aaaagcttgc atctacggca ctaagcccaa tcagatgaaa
    34501 aatatggagt gctattttta tctgattgtt cttactgctt gatgcagagc agctttttca
    34561 caacctctcc actaaacggt gttctcctgc caactcctcg gtcacaagtc acaatattca
    34621 acaaacatga gaagctgttt tttgaaattg ttccttgtga ctcggagcta aacggcaggc
    34681 tcacaacctc ttggtaaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg
    34741 gcaaaatatg aggaactatt ttttccgttt ttttctctaa tactcaggtc aaaacgctga
    34801 tttcacaacc tctgattcac ggtgttccag aagtagcttc tacggaaata agccgaaatt
    34861 tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa gctgaccact
    34921 tctgtcacaa cctcttattt tgattagaac ttgcgaaaat aaaccggtta aagtgtgtct
    34981 agcgcaagag atttgctata atagacgata agggtaaaat gtaacgagaa ggggttgaaa
    35041 aatgtgtatc aaattgtaac agattcttgt tgtgatctgc cataccatgt attagcaaaa
    35101 gaaaaagttg attttttatc aatgaatctc caattgaatg atcaagagtt agtagatgac
    35161 ctcggaaaga cattcaatta tgaccgctac atgaatcagc tgaaaaatgg tgcgatgcct
    35221 acgacatcac aaatcaatgt tggccgatat ttagaatttt tccgttctta tgcggaaaaa
    35281 cagattcctg ttttatatgt ggctttttcc agtggattaa gcggctctta cagtagtgcg
    35341 cttcaagcgg ttgaattgct gaaggaagaa tatgaagacc ctgagatcta tgtttttgat
    35401 acaaaagctg caagtattgg ggaagggctt ttagtattgg aagctgtaag attgaaaaaa
    35461 gaaggtaaaa gcatcgaaga aaccctagag tggctggaaa gtaattattt gaaagtccat
    35521 tcatgggtaa cagtagacga tctgaaatat ctagaacgag gcggtaggat ttccaaagca
    35581 agtgctactc ttggcagtct attgagtgta aagcctatta ttacggtgga taaagaagga
    35641 aggctgacga atgttgacaa agttcgagga agaaacaagt cgatccagac aatcgtcaat
    35701 gagacggtaa aaacaatcgt tgcaccactt gatcaaatcg tttatgtggc ttacgctggg
    35761 gatctagaga gcgcggagaa ggcaaaacgg cttttggaag agcagataaa gatgaaagat
    35821 gtgaagcttt atcccttagg accaacgatc gccagtcaca caggctatgg ctgtatcgcg
    35881 attttttcga tgggaatcag tcgataaaag cagtaactca ttctgtaaaa aagcccagaa
    35941 attgattgta acaaaaacag cgactcttaa aagatagatg agcatcctat ctcttagagg
    36001 tcgctgtttt tttatttttt aagctaaata ggccattatg cccataactc gttcaattgt
    36061 ttttgaatat ctgcattttc caaaaattca tcatatgtcg tatcagctcg atcgatcaca
    36121 cctttatccg aaacggcaat gatgcggttt gccaatgttt ggataaattg atggtcatgt
    36181 gacgcaaata agattgagcc agtaaatgcc atcaagccgt cattcaatgc tgtgattgat
    36241 tctaagtcta aatggttcgt tggatcatct aatacaagta cgttagcttt cgaaagcatc
    36301 atttttgaaa gcatgcaacg gactttctct ccaccagata aaacattcac tggtttcaat
    36361 acttcttcac cagaaaacaa cattcttcct aagaagcttc ttaagaaggt gttatcatct
    36421 tcttctttac ttgcatattg acgcaaccag tctaaaatcg ttagatcagt atcgaattct
    36481 ttcgttgtat cctttggtaa ataagaatta cttgttgtca caccccaacg tactgttcca
    36541 gtatctggcg taatttcacc catgataact ttgaatagcg ttgttgttgt tatatcattt
    36601 tctgcgacga aagcgacctt gtcttctttg ctcaaattaa aagatatatc atctaaaatt
    36661 ttctttccat caatcgttac acttacattt tctacctgca ataagtcgtt tccaatctca
    36721 cgttcaggtt tgaatccaac gaatggataa cgtctagaag aaggttggat atcgtctaaa
    36781 gtaatttttt caagcatttt tttacgtgaa gttgcttgtt ttgattttga tgcattcgca
    36841 ctaaagcggg caataaattc ttggagttct ttgatttgtt cttctttttt ggcatttgcg
    36901 tttgcttgaa gtttagccgc tagttgacta gattccaacc aaaaatcata atttcctaca
    36961 taaagtttga ttttaccaaa atctagatcc gccatatgtg tacatacttt gttcaaaaag
    37021 tgacggtcat gggatacaac gatcacagta ttttcaaaat tgatcaaaaa ttcttccagc
    37081 caattgatcg attggatatc cagaccgttt gttggttcgt ctagcaaaag aacatcaggt
    37141 ttaccaaata gtgtttgtgc taataacact tttacctttt gtccaccagt taattcactc
    37201 atttgctgat ggtgcaattc ttcagggatg ttcagacctt gcagtaaaac agctgcttct
    37261 ggttcagctt cccatccatt aagctcagca aattctcctt ctaattcagc tgctcgaata
    37321 ccatcttcgt cagtgaaatc ctctttcatg taaatcgcat ctttttcttt cagcacttca
    37381 tacagacgct tgtgtcccat gatgactgtt tcaagtacag tatagtcttc atagtcgtaa
    37441 tggttctgtt tcaatacggc catccgttca tctggtccca tagtaacgga acctgtggaa
    37501 ggctgcagat cccctgataa cactttaagg aacgttgatt tacctgcacc atttgcacca
    37561 atcaagccat agcagtttcc gggggtaaat ttaatattca catcatcaaa tagtttgcgg
    37621 tctgaaaagt gcaaactcac atcatttaca gtaatcaatt tttttcctca cttttatcat
    37681 tattagtttt gacaagtctt atagaattat ataggggaaa ggtaaaagat tcaaggcaat
    37741 cgaacattct ttgtgtttca cgtgaaacag aatgaaaaaa ataaaaataa aagcggagcg
    37801 aaaatagcta ctataggatt tattagtttg caacagcata atttttgacg ttatttataa
    37861 gagggagtac tataaaactg taaaagaaat gaaagaagga ttgaaaatgg atgaaaaaag
    37921 aaccatcgac tggggctcat tgattttggg aattttattt gtacttgtct cattgttatc
    37981 atttcaagac cctgtcggaa atttagttgc aattgtagta gtctttgcga tttttgcctt
    38041 tattaaaggg atatttgaac tgtttgtacg gaacagatta aaagagctaa caggatataa
    38101 aggaaagatg cccttaataa tcgggatcat cgatattcta gttggcgtct ttttcttatt
    38161 caatattggt gcaggagtcg cagcattgcc ttttgttttt gcagtatggt ttattgctga
    38221 ttcagtttta gcgttattta ctgctgactt ggcaagagga gtaagtgaag gatattattg
    38281 gtttacgatc atcgtcaata ttttaggaat tttattagga attttcttat tgtttaatcc
    38341 aatttcttct gtgttgacat taagcttttt agttggattc tattttatgt tatttggtat
    38401 cacacatatc gtctatgcat ttagataagt aaaatcaaac aaataaaaaa gccggcttcc
    38461 gattacagtt ttactgttgt aattggaagc cggctttttt atcatggaca aatatgcacg
    38521 aggtgatttt taggtgtcga gacaaattta tgcaaaaatg tgagaagcta tatacacaaa
    38581 ttttatctta atactcgaag catagcgcag ttgtcacaac ctcttttcat ataattcatt
    38641 caatactggc aaatcatgga cttcatattt ttctttgaat gcttggattt cttcttcaga
    38701 atattttctt ggatctaaat gcagatcttc tactggcaat gggcgcttgt tattgatctt
    38761 cacatcgatt actacaggac gatctgattt tgcagctgca tcaaaggcaa atcgaagttg
    38821 cgagtattct gtgactgtaa agctatttgc cccgagcgct tctccaactt taccgaaatc
    38881 tgcatcttct aaaaatacac caaatttctt ttgttccgta tcttcttgtt ctgcttcgat
    38941 gaaaccaaaa gaatcattcg aaaagacaac attaataatt ggaagctgat atttgacttg
    39001 tgtaatgata tcttgcatga ccatagcaaa cccgccatca ccacttaagg taaatacttg
    39061 tttttctggg tagcttagtt gtgcggcaat tcctcctggc acaccattac ccatagttgc
    39121 gaaccatcca gatgtcgtat gtttttgttt accgttcata ttcaataaac gaatagaatg
    39181 gatagtcgtg ttaccgacat ctgtgacgaa aatcgcatcg tcttcagcaa tacgattgat
    39241 ttctttatag acagcctctg gacgaatcgg ttcttcctct cgatcttcaa aagatttcaa
    39301 ccaatttacc catttttctt tattttcttg atttgctagg taccagctat cagcagggcg
    39361 agcatcccct aactcgacaa gtctttgcaa agctgtgttt gcatcaccga ggatcgacaa
    39421 agatgtttca tggcgtcgtc caaattttga cgcatcgata tcgatttgga taaattcagc
    39481 agttggatta aaaaatgcac gtccaaatgg gaagtcgcta ccgacaaata agatcagatc
    39541 ggcttctgcc aatgcttcat ttccgggttt agtagcgaca cgtccagcaa aaccaagaaa
    39601 gttttcataa tcatcaggaa taattccttt tgctagaacg gaagcgacaa caggaactga
    39661 aaaatgttct gagaattctt tgatttgcgg aaatccgttt cgcgttcctt gaccaacata
    39721 aagaactggt ttttttgctt tttcaagata aggcaaagca gctagcaaat ctttttcttc
    39781 tggtaatatc acacttgttt tgtgagtgtg agcggtggag aaaggttgtt cgtcaatttc
    39841 ttcaaaacca agatcaacag ggatagtcac gatagccacg cctttatgct cataggcggc
    39901 tttaatggct tcatctacta catgcggaag actttgtggt gtcatgactg tacgattgta
    39961 tacgctaaca tctgcgaaaa taggattttc atttagttcc tggaaagagt tatagttcat
    40021 ggatgtagaa gcaacttgtc ctaagaacgc tactagaggc acatggtcca tctgtgcatc
    40081 atacaaacca ttgatcaaat gtgtcgcacc aggtcctgca gagccgaaga cagcgccgac
    40141 tttccccgtt aattttgcat ctgcagcggc tgcgagtgcg ccgacttctt catgacgaac
    40201 ttgaatgtag ttgatttcgg ttttttcttg atatagcgca tccataattg aattgaaaga
    40261 tcctccggga atgccgtaaa tatggtcgat accccagctt tcaagaactt ttaccattgc
    40321 gattcctgca ttgatttttg acatggtgtt tcactccttt agcaatgatg atacataaat
    40381 tttttgtatc tagagtatag aactttttat cgaaaatccc aactaattcg tcttttcaca
    40441 aaaatgtagt catgtttttg ggaatatgct agagtagtac atagatagat tcaagagagg
    40501 ggaatggcat ggttgaatgg ctattgagac ttgaaccttg gcagcaagca cttgctggga
    40561 cagcttttac ttattttatg acagctcttg gtgccgggtt ggtttttttc tttaaagaaa
    40621 tcaaaaaaga agtgctaaac ttgatgttag gatttgcttc tggtgtcatg attgctgcaa
    40681 gtttttggtc tttgttagat ccggctatta caaaagcaga agaaaatgga gatattgctt
    40741 ggctagttgt aagtattggg tttggtttag gcggtgtgtt tttatatatg gcagataaaa
    40801 cactgcccca tatgcatttt ggaccacaac atgaagcaga aggattgcct acccatttaa
    40861 aacggacgat cttgcttgtt ttttctatta cattgcataa cattcctgaa ggtttagccg
    40921 tgggggtagc attcggtgca gcagcaactg cggataatcc gacagccgct atattagccg
    40981 ctgtttcggt ggcgctaggt attggtatcc aaaacttccc agaaggagca gctgtatcaa
    41041 tcccgttgcg acaagaaggt ctgagtcgta aaaaggcctt tgtttacgga caagcttctg
    41101 gaatcgttga accaattgct ggagtgattg gagcgctact agtaacgaaa gtggagctgc
    41161 tgcttcctta tgcacttgct tttgccgcag gagcaatgat ttatgtcgtg gtggaagaat
    41221 tgatccctga agcacagcag acattgtcca gcaaacgtca ttttgcagtt tttggcgtca
    41281 tgagtggatt tatcattatg atgattttgg atgtggcatt aggataaata aaaaaaatat
    41341 atatgatata tcaaataggg ccgcgaactt atatcgcgac cctatttttt tagtaagtta
    41401 tatcataatg aagtgaatgg tatcatacat taataatagt tttttctatg tgtatttcct
    41461 ttgatccagc gaacaagcca gatgataagt gcgattggga ttagaacttt gaccgcaaac
    41521 cataaaagcc cgcttaggac actgacaaaa agactgatga cgaagctagc tgcaattagc
    41581 actaaaagaa ccatgaagat atttaagaac atattttttt gacgcataca aaaccctcct
    41641 cttgttcatt ctttactata gaaaaagtat aacagggatt gtttaaaaac acctccaact
    41701 gaagactgat ttttacttca tctacttaaa tgatcaaaca attgcttttt ctctggttta
    41761 tcatctaaaa tagagcggaa aaggaggaga atatcatgcc taaaaatcgt cttgaagcat
    41821 ttacagatgc tgtaatcgcg attatcatga ctattttagt tttagaactt catgaaccta
    41881 acggagacac gtgggaggcg ctcgctgcat taggttaccg attttttatc tatattgtca
    41941 gttttatcat tttagcgatt tattggaaca atcatcatca tttatttcaa gttgtacata
    42001 agataaatgg acgggtctta tgggcgaaca gtttctttgt ttttgcgctt tcgctttttc
    42061 cgtttgcaac ttcatggatc agtgagtaca tcaatagcct ggctccagaa atgacttatg
    42121 gttttgttac cttgaccgct aatattgcgt attatatctt ggcaaaagaa cttgtcaaag
    42181 caaataaagg ccacgagaaa gcattgaagg cgatgttgaa taattacaag aaatcgtatc
    42241 tatcgattgg tttgaatgtg ttaggaattg tcttagggta tttagtagcg ccagtagccg
    42301 tgctgatcgc aaacatcgtg attctagctg cttggatcat cccaagtcgt accatcgaat
    42361 cacaatatcg gtaaaatgat ccgtgtttaa aatttaagag aaaaatatag aaaaaataaa
    42421 taaacgatca aatatccgag tgatactagt attcaaagag ggatgcagat ggatcaaaaa
    42481 agaattcatg taggactgat tactagtttt gtcacgatgc ttatttattt ggatcaaggt
    42541 catttgactt ggacagtagt tggtgtcgta ggatttttga cattattcac agcaataaaa
    42601 aaataaacat ctttatgtaa tctgatgttc tatctattta agaaaagcat gtttacagca
    42661 gtatgattct gttgtaaacg tgtttttatt tgtggaaaat ttaattttta gaaaagtgta
    42721 tcgaaaaata gatagttagt ttttccacag tggataactt cgtaagagat aaaaataaaa
    42781 aattagtcaa agaagggcgt atagatttct tttgatagga gatatacaac agaaatgaat
    42841 aaatattaac gtgttttcaa acagtataaa acggtgtggt ttttggaata aaaaaataac
    42901 atatctcatt ttacactttt gttattttat acttaaaaaa taacgacaca gaaaataccg
    42961 tgtctcagat ttctctacta cttctaaaaa ctactgtttt tttcctttga aatgccttca
    43021 aaaagtagga tcaggcagaa tatactggca gaatcaagga gaagggagcc taaataagga
    43081 gaaaaaccat agaaaatata aagtaattac ttataaaaca agctttttat agaaaaataa
    43141 tatacctgag tagggtataa attaagacgg aattcctttc tagattgaga tattgactag
    43201 gaagaatgtt aagattttaa gcctttaagc taaaaaaaaa ccctttttgt taaataaggg
    43261 gaatatagcc tgtcagtttc aaactgcaag tcgtcctgct gcaataatat agtagattag
    43321 agatgaaaat agattttttt aaaccaatga ctgaataaaa agaccgtcat agatacacat
    43381 tggaatgtgt ctattacggt ctttttttac gaacgatttt attgaagacg gacagttcgg
    43441 gtcaaaaata aaaaagctac gatcagaaat aagaataaaa tgtatcccaa aataatggct
    43501 agacggtcta acttatttgt cgatagatgt ttgtttagaa gttgataggc ccataaacct
    43561 atcagtcctc ctgttgtatt agttatcaaa tcagtgatgt ccgctacgcc aataccgaat
    43621 aggaattgaa tcaattctgc caagaagctt acaaggaaaa taatccctaa ttttttagaa
    43681 aaagaaagtc tcttgaaatt gacattcaaa agcaccccaa aaggaaaaaa gacaatcaag
    43741 ttataagtgg tctcacgtaa taccgtcgta ttttcaaaag aaaaagtaga aaaagggacg
    43801 agattgacat tgctgtaaga ataagtgaga aattgtggaa gattaaatga tagcttgaat
    43861 aaaatcaacc ataatagaaa gaataaataa atccctaata aaaattttga tacataccgc
    43921 atagacatct cctccattta aaaagtatac catcgaaaac cgctgaaaaa tcataaaaaa
    43981 gtatgaagtt taaggaccaa cgtagttatc gtacgaaaat tagaagcttt tttttgttgg
    44041 gaatccggtt tctttaacaa agctaagata gcgagttgct tggaaaagtt gctatctttt
    44101 ttctgtcaaa acgactcgga atgttcgttt tttgttctaa tttctccaag ttgtttactt
    44161 tttgatacta agtttatgaa aaatcaagaa atagttgtta tactaggtaa tgctgacaaa
    44221 cgggattggc atttcatctt ggttcagctt tttttccaat tactaggaag gagggataga
    44281 ttgttcaaga cttattttcg tttcaataaa atacaagata atccttttcg tatcatgaat
    44341 ctgatgctac ttatctttat tgtattatgg ttaggttaca taaatcatga ttttttgatt
    44401 tcaagttttt catcattagg gatctttact tttttctatt atcaaaacat accgatgaaa
    44461 tatttgctga aacgtatgtt tctgatcggt tgcggactgt tggttgcttt cgttttgggg
    44521 atcttatcga cttatgtttt atggcttgaa ccatttgccg tagctttggt tgctttttcc
    44581 agcagattcg tgttgcgatt attccatatt tctaaaccag gtggcttgtt ttttgcgatg
    44641 ctttctgcca tgggaacgag catgcagctg ccaatcgctc aattaccgat cgtctcactt
    44701 tattttttta tgggtgtcgt ttttgccctg attgcggcag tgattacaaa attactggat
    44761 tcacggcctg agcagacaat tgaaaaagca actttaaaag aaagatttca cgaagagcct
    44821 ttagtgatca ttgattctgt tttctacagc gctgccttat ttctttccgt ttatgtcagt
    44881 cacggcttga atctgcataa tccttattgg ttgaccttgt catgtgcatc gattttgcta
    44941 gcagaaaact tggatgcgat gaagcatcga caagtccaat atctgattgg atcgatgggt
    45001 gggttatgtg tgtcggcatt cttgtcattt gtgccgttta cgcagttgca gaccattttt
    45061 ctgatcactt ttctatatgg aatcgcacaa tttctagttg ctagaaatta tgcagttgct
    45121 aatatttttc ttaatccgat ggcgttgatg ctatctacac ttattcgtgg agcatacttg
    45181 atttctttga tcgaatatcg ttttttaggg atcgtcatag gaagtttcat cggtttaggt
    45241 gttgcgtggg taatgacggt tggtttgcaa cattatttaa cggttgttcg tcaaaaatta
    45301 gaatagaagg acaaatatat gtgccaaaag aggttatgac aagatttttg tcacaacctc
    45361 taattcaagg tgttcaaaag ccagattctc agcattaagt caaattcaca caaaaatgtg
    45421 gaaaggaact ttcaaaaaaa ttttatattt attctatcaa aaaattttgt ttatgatggt
    45481 aactgaataa actttcctga gatggtcaat gctttccttg aaagtcttac agatattctt
    45541 tcttcataga aagtttaagt tttatagtta gtgtacaata aaagtatgtt tataccatat
    45601 ggtgtccgga taatcagtca tttaaacaat gaggttcaaa gatatgaaaa ggggaaattt
    45661 gatgaagaaa ataagcaatg aaatccaaat tctggcagaa actttaactc ttcccaaagt
    45721 cgttatagag caaatgattg tacaagcaaa aaacatcctt gatgaggtgt ttgagcaata
    45781 tagtcatgaa ctaatggatc ctaataaagc aaaggcgact gcaaagaaaa tagacaaagt
    45841 ctatgaagag gaaccttttg cagcattagc tatttatcta tatgcagctt ctcaaagttg
    45901 gaaaaaaatt tatcaaccat tgaagattcc aagaactatc tatttggcaa caatgaatgc
    45961 ttttactaga tttattcatg aacatttcca agtaacagga agctatcgct ttgaccgtgg
    46021 tttttggatt tggcattaca ctagtggctt gatctttcgg attggtgaat tggagtacga
    46081 aatgacatat tttccgaaag ggtacacgga tctaagatta gaaggaaagc agtgcctttc
    46141 tcttcatatt ccttccgatg cagatttatc tcagaataag ataagagata gttacgaaag
    46201 tgccattcgt ttttttgaac tttattttcc tgattaccat taccaagtga tgtacacaga
    46261 tacttggtta ctatcaccca atcttactaa atggttgaaa aaagagtcaa aaatctgtct
    46321 ttttgcagcc gattatcgat tattatcagt tgatgaacag gacgatagtg gagtcccttg
    46381 gatctttgga cgagtagatg cccaaataca tgattatcca gaaagtacga gtttacagcg
    46441 acaagcaaaa gagcaattgc ttgcaggcga gcacattggc tctggcttag gtattcttac
    46501 ttcataagtt tagtacttcg aaatagttta aaagagcgtg agacaaaagt aaagaacact
    46561 tttgtctcac gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcggaaata
    46621 agctgaaatt cacaaaaatt tgaaaagcaa ttttcgtgaa tttcttcttg tttcttggag
    46681 ttaaacgctt ctgtcccagc ctctttttta gtgttctatc gaacacacag tacgttcaat
    46741 aggtaaacta gctataacaa tagatattaa agttaacgga caagagggcc ttttttaggt
    46801 agctaaaacg taataatgaa aatttatttc cagagatagg agtcaatcag ctagtctgat
    46861 cgactgtttt aacaagttga ctttcatttt aacttttgat accatttaaa acacaaatcg
    46921 taattgtttc gatttgtgtt ttttagcatg actacaatca aagaagaaag tgggtcgtcc
    46981 atatggaaaa aacagatatc tcaagtgcat accgccgctt gaaaagccca aatatcaaaa
    47041 cacgaaaacg tgcgctgaag atcatcaaag atgtgaaacg gaatagtggg aaaaggtaag
    47101 aagaaggaaa cttaattaaa aaaatagccg aaaaacgttt ttcggctatt ttcaataatc
    47161 ggtttttgtg taaggtttcc gaaagaactg ctgttgattt tccattttta acatatgata
    47221 aattggtaga atctttcttt tcaaattgat accattccct aattccagtt atatagttaa
    47281 ctacagaacc acaaagcacg tacgtttata aaagtattat ctgtagttat ttttcaattc
    47341 cctttcaacc tcttattttg accagtagta ttgatcactt taccttttaa cacctttgtt
    47401 cgtttttgaa acatttttag tcaagaatgg aaacgtaact acataatcaa aggttttgcg
    47461 aaatatttca tgaaatattt catgtagaag cgagcaatac ggttgcaaat aaccattatc
    47521 gtttaataag cagttacgaa agctcccaat atctctaacg ttcagctcac tccatttctt
    47581 ttcttcaaaa aaatcagtga ttcgtatctc tttctatttg tcgaaaaagt taactttaaa
    47641 aagtaacgcc gaaaaaatat gcaaaaaaat aaaaaagcag ttactattgc tagaataaca
    47701 tcaaggaata ataagttttg gttttcagat aatagtcgat aagttgtgta ttggaatttt
    47761 agatacagta ataaagtatt tttcatgaaa ttttgtgaga atcactatta caagtatctt
    47821 taataaaatt aatggttaag gaggaactta aagtagaatg taaatgaata gttgtagtca
    47881 gtcgattgtg atactagact caaagttgca ggaataagtt tttcaatttg tgattggaag
    47941 ataaaaaatg aaaaagaagg gctttttttt atactttgtt gattgtagtg tttattttcc
    48001 ctctgtttag ccaagtaaca ttttctatga ctcaaccagt ttcaagtgag gaacatgata
    48061 acctttttcg tgctacagaa gagtttaaga aatatcagga aaatattgtt ccggagactc
    48121 cattagctag tgagccaatt actgatattg atggaaacca aataggatgg tatatacagt
    48181 acgaagttat ggtggtaaat aatgactcaa tagtaaaaaa tacagtaggc ttagagctaa
    48241 caccgattga aaaggtgagt tcattgttaa cgtatattta tactgatgaa agtgacgaga
    48301 ctgagatcat tttaacggat tactcaaaaa ttgctactga taaaaagtat atattgtgga
    48361 tgtagacact agtgaaatac tttatgatat agaaattgat gaaaatttac tagatgtagc
    48421 acaagaaatc gatcatcaaa agcaggaagc tattcgatat gctggtagaa aagggaaaag
    48481 aaaatattta ttacgtgaat gtagcaaaag ttagagaaga tgaaaatgag tggaaagaat
    48541 tcaagagtcg ctactcaatt aactcgactc cgacatttac agtttacaga gaaggatcga
    48601 tagaaaaaac tgttttttgg actaaagaaa gtggaatgtc tttagctgaa gtagaagagt
    48661 ttttggatta tgttagtatg caacagtaag ggagttctta ttatgaaaaa ttttgacaca
    48721 tattatgtta ttgttttttc gatatctttg ctgttaatat tactaacttt aatgcagtat
    48781 aaagagtatc cagagtattt tattttaact tttgtatatt tagtaagtag ctacacactt
    48841 ctatataaat tcagaagttc ttctagagtt tctaaagttt gtttcttaat tagcttattg
    48901 attctataat atttttgatt tatataggaa attaaaaata ttatagaatc aacactcaga
    48961 gaacgggttg gtttttaata gatttaataa gtactgataa tgaaatttct cctggttggg
    49021 aaaacgaagt tggttaccct gtagaagaat tttttcaaga ttactttgcg gagtatgccg
    49081 ataggataat gagagattac gtaacagata aaactcaaga agtcatcaat caatcccagt
    49141 cattaaatga attatctgat aaggcgaaag aagaagcagt tgccattatt tcttcaggga
    49201 ttagtgacta tattgatatg agtggtgaaa tcaattatgg cgataaagac aaaattgtac
    49261 gcatgataaa agcttttatc aaaacttttg atgtgaaggc agatcttaag tttaatgata
    49321 cttacctagt aggaaaatta attaatatcc ttgggacaga gaaagatacg gaaacgttta
    49381 tttcctcttt gtctatgttg tttacagata agcatttttc aactcagctt ggtggagagg
    49441 aactagtgga aatcttttaa ccattacgcc cagcattaat aaaagtatat caaaaaagta
    49501 ctcctgatga tttttaagat tggtttgaga aataatgtga aaacactatt tttaatgtta
    49561 attatagata gagatgaacg cgtcatatgg ttaaaagaat gaaaaagtca aagatacact
    49621 gctatatttc actaaggata tagcagtgta tctttcatgt cgtttcactg gcagtttttt
    49681 ataaaaggag gtgtgcattt cagttgcttt tctttggtag ttagttgaat cgtttaagaa
    49741 ttaacggatg tggcagacag gtgctctgtc caaaaaccag taaaatcttt gatggttcca
    49801 tctttattta gctgtgcctg ttcaaatact gttttgtttt taccgaatgg atcaattgca
    49861 ataattgttc cgatccccgc acgtttggca gcaagtaatc ctgagtaagc atcttcgata
    49921 acaagacaat cagccggagc taagctcagt ttgtctgccg ctttaagaaa aatatccggt
    49981 tgcggtttcc cagggaaaga gccgtcgtca tagacaatct tgtcccagtc aaaccagcgg
    50041 gctaaatcga aaatatcaaa ataaaaagca acattctctt tgacagtagc cgtggcaatc
    50101 gttaatggaa tctgttggtc agtcagctgg tcaagagtcg cttcaagccc ttttgtcaac
    50161 tgaagctcgt tttcattttg caagcaaagc atacgataat agctttcttt ttcttctgac
    50221 aatacggcga tctcagaggc ggtcaaatgc tctgaaatga aatgtttcaa aatctccgta
    50281 ttcgtccgac catgaatatt ttttaaaata tcctcgtctg ataaaccatc ttttgtatga
    50341 tcatgtatca tatgcagcca agcagcttca tgcagatgag agtccaaaaa cattgttccg
    50401 ttgaaatcaa atataatccc tttcatagtt acgctcctat agtggtattt tcggttgaat
    50461 cagcaatttg cagatcgaca tattgtgcat agtgctcttg aacctcccgc gagatctggc
    50521 gatccgtaat gagcagatcg aaatcatgca aattataaaa cacataaaaa tcatctcgat
    50581 tgaatttttt attatcaacg agtagatatt tcttacggga attatttaga gcgatctgct
    50641 gtgcttctcc ttcttcggta ctgtaagtag agatcgcttc gttgtgaacg ccatttgaac
    50701 tgataaatgc ttttgtaaac tttagtcttc ttaaattgtc gttggtgatc ggtccgacaa
    50761 atgcgccggt atttttccgg aaatcaccgc caatcagtag aatttctggt ccatctgctt
    50821 gagcaagaat atcaaaaact ggataattat ttgtaatgat ccgaattttc ttgttcagta
    50881 aatgcgtcgc caatagttcg attgttgtac ctggtcctaa gaaaatcgtt tctccctcgt
    50941 gaatcaagga ggctgctgtg gcagcaattt cttttttttc ttgaatctgc agagtggctt
    51001 tttcagtgtg agaaagttct tgatctaaag tgtaggaaag actttgagcc cctccatgga
    51061 cacgcagcag cttgcccgat ttttctaatt catctaaatc tctgcgaacg gtcatatcag
    51121 aaacatctaa ttgattgatg atttcattaa cggtaaggat tcctttttta ttgaccattt
    51181 ctacgatagt aagcaatctt tcttttttca acattgtctt cacctctaat ttaaggataa
    51241 tctatcatat aaacggacaa cagtcaatct aattcgaaca aaagtaaaca tttagggtgg
    51301 tttttatgtt tgttacaata gattttattg ctgttttctg gtttttatga ttatttgtgt
    51361 ttgtttttgt tgacaaatgt tttggatgcg tttacaatgc aatcagttag aaagagcgaa
    51421 aactgattat agatttgagg agagatgtac atgcttaaat taccagaaga ttttattttt
    51481 ggcggagcca cagcagccta tcaggttgaa ggagccacta aggaaggtgg caaaggcgct
    51541 gttgcttggg atgacttttt agaggaacaa gggcgattca gtcccgatcc ggcaagtgat
    51601 ttttatcatc aatatgcaaa ggacattgaa ttgtgtgaac gttttggtgt aaatggtcta
    51661 agattatcca ttgcttggag ccgcattttt cctgatggag ctgggaaacc aaatccagaa
    51721 ggaatcgctt tttatcatcg tgtgttcgaa gaatgtaaga aaagaaacgt aacgccgttt
    51781 gtgacgttgc atcattttga tacccctaaa cgtttgtttg accatggaga ttttttgaat
    51841 cgagaaacaa tagaagcatt tgtttcctat gccatttttt gttttcatga attcaaagaa
    51901 gtcaaggtgt ggagtacctt taatgaaatc tatccagttg caaccaatca atatttgtta
    51961 ggtgttttcc caccaggaat caaatatgat tttacaaaga tcgtcgcctg tcttcataat
    52021 atgatggttg ctcatgcccg tgtagtgaac tatttcaaag aaaacgaact tccgggtgaa
    52081 attggtgtag ttcactcatt agagacgaaa tatgcggcaa cagacgcgcc ggaagataag
    52141 catgctgcct ttttagacga tgcattgtcg atccgtttct tattagatgc tacctattta
    52201 ggctattatt caactgaaac cttgactgct cttgatgaga tatgtgaagc aaatcaggcc
    52261 agctatcatt ttcctgaaga agatttcgtt gaattgaaaa aagcatccac gcgtaatgac
    52321 tacttaggga tcaatcacta ccaatgccat tttgtcaaag cttacgatgg agaaaatgca
    52381 atccatcata acggtacggg tgaaaaaggg acctctgttt ataaagtgaa gggaatcgga
    52441 gaacgtattt ataaagaagg aattcctcga actgattggg actggctgat ttatccagaa
    52501 ggtctatatg acttgttgct gcgaattaaa agcgattacc cacattacaa caaaatctat
    52561 atcactgaga acgggatggg gtataaagat cagtttgaag atggcattat tatggatcag
    52621 ccgagaatcg actatttgag agtctatttg gaatccttaa gcaaggcgat aacagccggg
    52681 gtaaatgtga aggggtattt tttgtggtcg cttatggatc ttttctcatg gacaaatggg
    52741 tataacaaaa ggtatggctt gttttatgtt gattttgaaa cccagaagcg ttacccaaaa
    52801 gaatcagctt actggtacaa gttggtcagt gaaaccaaaa cgattattta ataagtgata
    52861 atggaggaag aaaagatgaa taaagaggaa ttacaaatgc ttggttttga gatcgttgca
    52921 tattcaggcg acgctcgcag tacattattg aaattattga aagaagtaag acaaggaaac
    52981 tttgaacatg ttgattcggc gttgaaagaa gccgacgaaa atttaaccct tgcacataat
    53041 tcgcaaacaa aaattttagc ggaagaagca tctgggaaag agatggagat gggattcatt
    53101 tttatccatg ggcaggatca tttaatgacc actttattgc tgagagatct gattcaagac
    53161 tttattgtac tgtacagaca gaatcaagga taggagaaga acgctatgga tggaatcatt
    53221 aaacaaatcg aaaaagggaa agcatttttt gaaaaaatct cacgtaatag ttatttagga
    53281 gccgttcgtg acggattttt aacagcgatg ccagctattt tattttcaag cattttcatt
    53341 ttgattgctg cggttcctga gatttttggt taccaatggc ctgaatctgt ctccacatgg
    53401 ctatggaaag tctataatta ttcgatgggt gttgtagggt tactcgtttc agcaaccact
    53461 gctcgctgct tggctgattc gatgaatcgt cgcttaccga aaaacaaagt aatcaacacc
    53521 acctctgtga tgctggcctc tgtggtaagt ttcctgttgt taagcgtctc tccgattgaa
    53581 ggtggatttt caacggaata tatggggaca aagggactac tggcttcctt tgtcgctgca
    53641 tttttaacag ttaatttata taagttttgt gtgctgaaag atattaccat taaaatgcct
    53701 aaagaagttc ctggaacgat ttcgcaaacc ttccgagata tttttccttt ctctttttca
    53761 gtatttgcgg ccgttttaat tgatttaggc attcgacaaa tcttccaaat ctcatttgca
    53821 gaagcaatca ttacggtgct gcagccgcta tttacagcag ctgacgggta cttaggaatc
    53881 gctattatct ggggagcgat ggcgctgttt tggtttgtcg gtgttcatgg accgtcgatc
    53941 gtggagccgg caattgcggc aattatctat gccaatgtgg aaaccaatct gcaattgttc
    54001 aattccggtg aacaagcttc taaagtactg acggtgggtt tagggaattt tgtaggaact
    54061 atgggaggaa ctggggcaac attggttgtt ccttttatct tcctactctt tgctaagtct
    54121 aagcagttga aggcagttgg gaaagcttcc tttattccag taagtttcgc tgtcaacgaa
    54181 ccattgctat ttgcggcacc catgattttg aacccttatt tttttattcc atttttgtta
    54241 acacctgttg taaacgtttg cctgttcaag ttttttgtcg atgtattggg catgaacagc
    54301 tttatgtacg ttttgccttg ggcaactcca gcaccgatcg gtttggttct aggaacgggc
    54361 atgggtatct tagcttttgt tctagcagcg gttctaatcg tcgttgactt cctgatctat
    54421 ctaccatttt gcaaagcata cgatgctgtc ttagtagaga aagaagcaca aaaagcagag
    54481 gtgatcgcaa ccgaggaagg tgcttctgcc gatgtacgtg aggaagtacc tgtggcagcg
    54541 agtcaagtta tcagcgatgc aaataaagaa atcaatgtgt tggtactttg tgctggcgca
    54601 gggacaagtg cgatgttagc taatgcttta aaaaaaggtg catctgaatc gaaagcaccg
    54661 atcagtgcaa tggcgggtgc ttatggttct cattacgaaa tgctgcagga ttttgatatg
    54721 gtggtcttag caccgcaagt caattcttac tatgatgata tcaaagaaga caccgatcgc
    54781 ttaggaatca agctggttgc gacaaaagga gcagaatata tcggattaac gagagatcct
    54841 gaaaaagctg ttcagtttat tctgaaccaa tttcaataaa ggaggagcca taatgaaaat
    54901 gggaatttgg ttgcgtaaag ctgttttatt tgcagctgtg ttaggggctt tgggggctgt
    54961 ttcaaaaact gttgaagcat ctgccagcga atttattcgc ggagcagata tttcgatcct
    55021 gtcagatatg gaaaaatctg gtgcaaaata ttatgaagac gatatttcaa aagatgcctt
    55081 agagatttta aaaaataatg gtgtcaacta tgttcgactg cgtttgtggc aggatcctta
    55141 taatagtaat ggagaaagtt atggagcagg gacaaatgat ctggaaacga cgattgacct
    55201 tgcaaaacga gcaaaaaatc tgggacttaa ggtgctgctg gattttcact acagtgattt
    55261 ttgggttgat cctgggaaac agaatcttcc taaagcatgg caaggtctga cctttgaaga
    55321 aatgaatacg gcattgtacg actatacaaa gaacgttctg tcggaaatga agcagctgga
    55381 cgtttatcct gatatggttc agatcggcaa tgaactgaat agcggaatgc tctggcctta
    55441 tggcaagtct tggggagaag gcgggggaga atttgatcga ttggctgctt ttttgaagtc
    55501 tggtatccaa gctgttcgag acactcaacc taaaacaact ccagtaatgc tccacttagc
    55561 tgatggtggc gatacaggag catttacttg gtggtttgat gaaatcacga gtcgaggtgt
    55621 gtcatttgat ttaattggag tgtcgtatta tccgtattgg cacggttcaa tgaatgaact
    55681 tcaaaccaat atgaatgcga tcagccaacg gtatggtaaa gaagtgatcg tagttgaaac
    55741 agcttatggg catacaacag cgaatgccga tactatgcca aatgcttttg gtgaagccga
    55801 agcagctgcg gggggatatg aaccaacacc gacaggacaa gcagagtatt tgctggatct
    55861 tgccgatcgg attcaggcag taccgaataa tcgcggggcg ggcttcttct attgggaacc
    55921 tctttggtac aacggaaatg tgagttgggc aacacaagca ggtatgaatt atctcagtgt
    55981 tcaatccact atgggaaacg aatgggacaa ccaagcgatg tttgattttg ctggaaacgc
    56041 cttgccaagc ttgcgtgcgt ttaaacaagc aggggcgcaa ataaatctag ttaaaaatgc
    56101 aagtttcgaa agcgatggac caacgaccag tccttccaat tggcaaacct ggtttcaaca
    56161 aggaaccgct aagggtacga tcaaaacgga agcgggcact ttttttgggg actacaaact
    56221 aactttttgg caggatcaag catacgaggc atcagcttat caaaatgtta gtggcataag
    56281 caaaggaact tacacattga gtgcctatgt aatgtctggg ggagagtttg atactaatca
    56341 gttatatatc aaaaattatg gtggagcgga actaaatact gcggttgtta aaacaagtga
    56401 atggacaaaa attacaatca aagacattcc aattacaaca ggtgtttgtg aaattggggt
    56461 ttatagcaag gcttcaggaa atgcttggac gaacgttgat tttgtttcat tggtgaaaca
    56521 atagactgcg gatcgtttcg attcaagatc ggaggttccc ttcagccaca tcgttagcgt
    56581 agaaggcagg aatcgaacct gcacctcgcc tttgccaaaa ataaccagaa acgatttcca
    56641 gtcattttta ccaaaacgag taaagcacca gacttcatct acactttgta ttatgctaaa
    56701 gagagttcaa cgatttcgta agaagcaatg aaaaaattgc aaaaagttgt gcagataaca
    56761 taaagtttgt ttaagaaagg gtaaccttag aattccgtcg tgaatatgat ttgagcactt
    56821 agatggatag aaaaaagttc tcggaaaaca gttcgttttt cgagaacttc tttttatgat
    56881 aagaatgaaa caaattaact tatattatag tctcttttgg tagggaacca tcttattttt
    56941 aatgaaaatc aagcatttta gctattgaag aatgttgatt tatagggatt ccccctccat
    57001 attatgttgg ctctttattc ccactccact gttgctggtg gtttagaagt gatgtcatac
    57061 acgatacggt tgacgtgggc tacttcgttt acgatacgta cagagatttt ttgcaagact
    57121 tcccatggga tacgggcaaa gtcagcggtc attccgtcga ttgaagttac agcacggata
    57181 ccgactgtgt agtcgtaagt acgtccgtca cccataacac cgacagagcg gatccctgga
    57241 agaacagtga aatattgcca gatatcacgg tcaagtccag cagctgcgat ttcttcacgc
    57301 aagatagcat cagattcgcg tacgatttct agcttgtctt cagtgatttc gccaagaaca
    57361 cgaataccaa gaccaggacc agggaatggc tgacgccaaa cgattgaatc aggcatgcct
    57421 aactgagtcc ctaattcacg gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat
    57481 tcaaattgca tatcttctgg cagtccacct acattatggt gagatttgat cgtctgtgct
    57541 gtttctgtac cagattcgat aacgtcagta tacaacgttc cttgtgctag gaaagagacg
    57601 ccttcttcac cagcaagttt tgttgcttcg tcatcaaaaa catatacgaa ttcattccca
    57661 atgattttac gtttttgttc tgggtcagat acacctttca acttgtctaa gaagcgatct
    57721 cttgcattga ctttgatgat gttcaagccg aattttccgc ctagactttc cattacttgt
    57781 tccgcttcgc ctttgcgtag cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg
    57841 atcgcttttt gtaaaagaac cccaacgaca ctagaatcaa cgccacctga aagaccaagc
    57901 aagacttttt tgtcaccaac ttgttcacgg attttttcta cttgcatatc gataaagtta
    57961 tccattgtcc agttaccttc acagtgacaa acatcaaagg caaagtggcg cagcaattcg
    58021 attccgtatt cggaatgacg tacttctgca tggaattgga taccataaaa attacgtgtt
    58081 gtgtcttgga tagaagcaat cggacaatct ttgcttgttc cgactgtttc aaagccttca
    58141 ggaactttag ttaccaagtc accatggctc atccatactg tttgttgttt tggtgtttct
    58201 ttaaacaaga cagcttgatc gcttgttact tctaacaagg ctttcccata ttcgcggttt
    58261 ttagcaggct ctacggaacc gccaagtttg tacgtgatca attgcatacc atagcaaatc
    58321 cctaatacag gaatacctaa attgaagatc tcaggatcga tcccaaatgc attctcatca
    58381 tatacactgt ttggtccgcc agaaagaatg attccctttg gattcatcgc ttttacttct
    58441 tctgcagtaa tgcggtggct caataattcg gaaaagactc caagatcacg aatacgtctt
    58501 gtgatcaatt ggttatactg actaccgtag tctaatacga taatcttttc aacgttcgtc
    58561 atatcggcaa cgtttgtcaa atttattacc cctatccctt taaattttat ctcaaaatag
    58621 tcaaactatt ttaaaatgct aatattttcg catgaaaatc gaatcgatga tatgattttc
    58681 agttttatgg agaattatat cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt
    58741 tttcaaattc acatttttcc atacatcttt tgccatttta aaggcttctt cacgatctcc
    58801 gatagcaaaa cgataataat aattctctgg attttggaaa gccgtatcca gtaacgcacc
    58861 aaaacgatcc aaataccatt tttcgatcag cacgggatcg gcatcgacat agacagaaaa
    58921 atcaaaaaag tcgctgacgt agatttgctg attcgcaggt aattgaagcg tattgatccc
    58981 ctcaacgatc aagatatcag gctgctggat caattcgtac ttgtctggaa tgatatcata
    59041 cacatcatgt gagtaaacag gtacttttat ctcttcctga ccagatttta cacggttcaa
    59101 gaaatcgatc agcatctcca tatcataact ttcaggaaat cctttacggt ccatgattcc
    59161 acgctctttt aatatacgat ttggataaag aaatccgtca gtcgtgatca gctgaacgtt
    59221 tcttcgtttg aaggtacgag acaaaatcgt ctgcagcagt ctggctgttg tactttttcc
    59281 aacggctaca cttccggcga tcccgataat aaaaggcggt acttctacgt atttatgaag
    59341 aaataaacct ttactcaaga acaaagattc aaattctttc atataaagat aaatcagatg
    59401 agcaagaggt acatagatat ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt
    59461 gatattatct agttcatctt gtgtcaaagg tgcttgccca ttacgataaa attctcgcca
    59521 ttcttctctt gccacacggt agtagttcat tggatcattc atattagcct cctgcgttct
    59581 cccatcaatg gaactatttt aacacaaaat aaacgcaaac cccaccactt aagagagatt
    59641 gccgatcttt ttgtataatc tttataatag aaagaaacgg agtcttattc ttgacttgcg
    59701 cacggataca taaaaggata gactgttgtc atgaaagaaa tgagaaggat ggaagacatg
    59761 acaaatcatt actattctga acgcccagat acggcgcacg attttgaaca atgggctttt
    59821 gagttaaaag gcagaacctt tcaatttgta acagattctg gtgtattttc acgtgaaaca
    59881 gtggattatg gttcacgtgt cctgattgat gctttcgatt gggaagagtt acctgatgaa
    59941 ggaaagatct tagatgtggg atgcgggtat ggaccgattg ggttagcttt ggcatttgcg
    60001 acacagcggt ttgttgaaat ggtcgacatt aatgaacgag cggtaagtct agcgcaagga
    60061 aacgcaaagc gtaaccaaat cgaacatgtt gatatccatc aatcgaatat ctatgaagca
    60121 gttcatgaag aaacctatgc agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa
    60181 gttgtacatg aaattttgac aggcgcatat cctcggttga agaagggcgg tacactgaca
    60241 attgtgatcc agaagaaaca aggagcgccg agtgcgcaaa agaaaatgga agaaacattt
    60301 ggtaatgcag aaatcgtcac aaaagataaa ggatattata tcatcaaaag tgtgaaagaa
    60361 taactagctg aaaaatagtg gagcgacgaa agagtggaac tgggcgtgca tgtacgggta
    60421 cgtatcagtt ctttttttgt tgagaagttt ttaaaaacaa agaactattt tttcttcaaa
    60481 aagaaatagt aggaacagag tcgttgtttt ttacgataaa ataaataaga tacagaactt
    60541 gtatagaagg ctgccaagtc ggtagataaa ggaggttttt atcaaaaaac atactttcct
    60601 tttttctcta ttcttttctt gggggttttg gtacactgat agggaattta gatagaaggg
    60661 agccaatagg atgaagctga ccatcagaga tatcgcagaa atggcaggcg tatcagtaac
    60721 aactgtctca cagattttga ataacaaagg aagcagattt agtgataaga caagaaaaaa
    60781 agtgttgtcg atcgtgaatg aacatcatta taagcccgat tatttcgctt caaatgtgat
    60841 caatcgacat tcaaagacca tcggaatgat cgtccctgat gtcactgatt tcttcttctc
    60901 caaactgatc gaaggtgtag agagctattt gaatcctttg ggctatgtga tcatgttatg
    60961 caattctcgt catagccaag aaaatgagat caagtattta caagagcttt cccaccgctc
    61021 agtggacgga atcttgctgg ccacaccaaa tattttacct gagaaatatg cattagacag
    61081 cggtttttat caaaaaatgc caatcatttt aatcgatcgc ggattgaatc gtcgggataa
    61141 cggacggctt atcgtaaagg aatatgaggg cgcctatcaa gctgtttcgc tgtttattga
    61201 aaatggccat acgaagatcg gcatgctgaa ggaaaccact ggatactatc aattagaaga
    61261 acgtttcaac ggatatcgtc atgcgctgaa agatcatggc ctgcctttta atgggaaatt
    61321 tgttgaacat ggagagttga ctgtccaagg tggatatact gcatcaaaaa aattactcaa
    61381 acataaagat atcacggcta ttttttgcgg gaatgatgcc atggcgatcg gatgctatca
    61441 ggcgatcgat gaattgggca aaaaaatccc agaagatatc tcagtcatag gattcgatgg
    61501 attaaagctg tcagaataca tgattccgca attgacgaca gtgcagcagc caagttttga
    61561 tattggattt tatgctgcac gtttcctgat cgatacgatc gaatttcctc aaagaaaagt
    61621 tccgaacaaa gtgttcgaaa caaaattaat tattcgtgag agcgtaaaag tattgacaaa
    61681 gggctaactc ggcggtatat tgcttatgta agcatttaca aaggctagtt agtgcttttt
    61741 ttatttttag taaaccagtt tactaaagtg gtttaccttt cctaaaaata atgtataata
    61801 ccgaatgaag acaaggagga tcaggcaatg cgaatggtgg atctgattga aaaaaagagg
    61861 gatggaaacg agctgtcgaa agaggaaatc gagtacatcg tcacgaacta tacgaatgga
    61921 aagattccag attatcaagt cagtgcatta ttgatggcaa ttttttatca agacatgaca
    61981 aatgaagaaa tcacgaactt aacattggcg attgctaatt ctggtgatgt catcgatttg
    62041 agttctcttg aaggaataaa ggtagataag cattcgacag gtggcgttgg tgacacgacc
    62101 acattgattt tagcccccct agtagctagt gtcggagtga cagtggctaa aatgtctgga
    62161 cgcggtctag gttacacagg tggtacacta gacaagctag aagcaattcc cggatttcag
    62221 atcgagcttt cggatgaaga atttgtacgc attgttaatg aaagtaaagt agcggtaatt
    62281 ggtcaatcag gaaacttggc accggcggac aaaaaattgt atgccttgcg tgacgtcaca
    62341 gcgaccgttg attctcttcc gctgattgcc agttcgatta tgagtaaaaa aatcgcggca
    62401 ggagcagatg caatcgtttt ggatgtgacc actggagacg gtgctttcat gaagaacatc
    62461 gaagatgcaa gacgtctggc aaagaccatg acgagcattg ggaaactggc taaccgagaa
    62521 acagtggcgg ttatctcaga tatgtcagaa cctcttggcg aagctatcgg aaatagtcta
    62581 gaagttgtcg aggcaatcga aacattacaa ggaaatggtc cagaagatct agtagaaatg
    62641 tgctacgcct taggaagcca aatggttgtt cttgctggca aagctaagac aaccgatgaa
    62701 gcaagaacgt tgcttcaaga agctctggaa tcaggtaaag cgttagcaaa attcaaagaa
    62761 atgatccaaa atcaaggggg agacccagcg atcgtggaac atccagaacg aattttgact
    62821 gcacgctaca caatggagct tcctgctaaa caaagcggag ttgtgtcaaa aatcgtggca
    62881 aatgaattag gaattgctgc aatgatgcta ggtgctgggc gtaaaaccaa agaagaagat
    62941 attgatcacg ctgttggatt gaaactgcat aaaaaaattg gtgacactgt gacaaaaggt
    63001 gagtcactat tgacgatcta tagtaacgac gaagaaatca cttctgtcat tgaattatta
    63061 tataaaaata ttgaaattgg tgaatcggca atgaagccaa cgttgattca tgacatcatc
    63121 acagaataaa ggaaaaaagc ggactttacc gttttaaaga aaaggggaaa agaaatggaa
    63181 ctaaaccgaa tgatcgacca tactattttg aaagcagacg catctaaaga agctgtgatg
    63241 caaattatcg aagaagcaaa aaaataccat ttttattctg tctgcatcaa tccagcatgg
    63301 gttgcgctag cgaaagaaca attacaaggt gagccagtag ccgtatgtac agtaatcggg
    63361 tttcctctag gagcaaacac acccgagaca aaagcatttg aaacaacaga tgccatcaat
    63421 aacggtgcag atgaagtcga tatggtcatc aatatcggtg ctttgaaatc aaaggatgat
    63481 caacaagtcc aaaaagatat cgaagcagtt gttgaagcag caaaagatcg tgcgcttgtc
    63541 aaagttatta ttgaaacatc gttattagat agagaagaaa tcatccgagc ttgcgaaata
    63601 gcaaaagctg caggcgctga ttttgtcaaa acatcaactg gtttctcaac aggcggagca
    63661 aaggtagagg atgtccgttt gatgcgtgaa actgtaggac cagaaatggg tgtcaaagct
    63721 tccggcggta tccataacga agaagaagca atggcaatga tcgaagctgg tgctacaaga
    63781 atcggaacaa gcgcaggagt agcaatcgta tctggttcaa ctggtgaagg ctattaattt
    63841 tttcaaagga gaagctcatg gcagaactca aacaagaatg gatcaacaca gctattgaag
    63901 cgttagataa agcctatgtt ccttattccc attttccggt aggcgcttgt ctcgtaacgg
    63961 aatcaggcaa gatttatcaa ggcatcaaca ttgagaatgc atcatttgga ttaacgaatt
    64021 gtgccgagcg cacagctttt ttcaaagcag tatctgaagg agaaaaaaca tttacgcatc
    64081 tagtcgtagc ggggcacacc cccgatccta tctctccttg tggtgcatgt cgacaagtaa
    64141 tggcagaatt ctgttcccct gatatgccgg ttacgctagt aggagacaat ggtgtgacga
    64201 aggcaacgac cgttcgtgca ctgctgcctt atgcatttac tgaaaaagat ctataactca
    64261 tgttcattca gtcagctgac tgttgaaaaa taaaacaatt attttaggag gctttacaga
    64321 aatgaaaaaa gcaaaattat ttggtttagg tgctgtcgca ctagcagcag ggttattttt
    64381 aggtgcatgc ggcaacaacg gctctactga ttcatccggt ggcaaaagct catcagacac
    64441 aacaactgca gcattgatca cagacacagg tggtgtagac gaccgttcat tcaaccagtc
    64501 agcttgggaa ggactagaaa aatgggggaa agatcaagga ctttcacgag gaaatgatgg
    64561 cttccaatat ttccaatctt caaatgaatc agattacatc ccaaatattg accaagcatt
    64621 gaatgctgga ttcaaaacga tttttggtat tggttataaa ctaaaaccag cgatccaaga
    64681 acaagcaaca aacaatacag gtacgaactt tgttattatc gatgatgtca tcgatggatt
    64741 agataacgtt gtatctgcaa ctttcaaaga caacgaagct tcttatcttg caggtgttgc
    64801 agcagcttat acgactgaaa caaacgtagt cggctttatc ggcggtgtaa aaggtgaagt
    64861 aatcgatcgt tttgatgctg gattcaaagc cggtgttgat gcaggtgcga aagaattagg
    64921 aaaagaaatc aaagtattga atcaatatgc tggtgacttc tctgctccag ataaaggacg
    64981 ttcaattgct caaggtatgt atgcacaaaa cgcagatatc atcttccatg cttcaggcgg
    65041 tacaggtaac ggtgtattcc aagaagcaaa atcattgaac gaatcaggcg acaaaaaagt
    65101 ttgggttatc ggtgttgacc gcgaccaatc agacgaaggc gaatacacat taaacggcga
    65161 aaagaaaaac ttcacattga catctacact gaaagcagtt ggaacagtag tagaagattt
    65221 ggcacaaaaa tcagcggacg gtaaattccc tggcggcgaa cacactgttt atggattgaa
    65281 agaagacggt gttggtctaa cagaaggaca actttctgac gaagcgaaaa aagcagttga
    65341 tgaagcaaaa gaaaaaatca tttcaggtga cgtaaaagtt ccagaaactc ctgaagaaaa
    65401 ctaaaaccat ttctatagcc ttgttagaca catgtttgac aaggctatgg tttgattaga
    65461 acaagaattg ttcatttatc caagctgcct tgtgacagtt tggataaggg aacaactccc
    65521 tgaagtaatg tttgtttcaa aagaagaacg ctcactaagc gtgaatctta gtcaatcgtt
    65581 gccctagata gaaatcgtta ggatgtgaaa aaaaggtggt tcaagaaaat attgtcatag
    65641 aaatgcagaa tattaccaaa gaatttggaa cattcaaggc aaatgacaac atcaatttac
    65701 aagtaaaggc aggagaaatt catgcgttgc ttggagaaaa cggtgctggc aaatctacat
    65761 tgatgaacgt gctttccgga ttattagagc cgacatcagg gaaaattttg atgcgtggga
    65821 aagaagtaaa gatcacaagt ccgaccaaag ccaaccaatt agggattggg atggtccatc
    65881 agcactttat gcttgttgat gcctttactg taacagaaaa catcgtgttg ggaagcgagc
    65941 ctagtcgcgc agggatgctt gaccataaaa aagcacgaaa agagatccaa aaagtttctg
    66001 aacagtatgg attgtcagtc aacccagatg cttacgttcg tgatatttca gttggaatgg
    66061 aacaacgggt agaaatttta aaaacacttt accgaggagc agatgtactg atttttgatg
    66121 agccgacagc tgtattgacc cctcaagaaa ttgatgaatt aatcgtgatc atgaaggaat
    66181 tagtcaaaga aggcaagtcg atcattttga ttacgcataa gttagatgaa atcaaagcag
    66241 tagctgaccg ctgtacagtt atccgccgtg gaaaaggaat cggtacagtc aacgttaaag
    66301 acgtaacctc acaacaatta gccgatatga tggttggaag aacggtttca ttcaaaacga
    66361 tgaaaaaaga agcgaagcct caagaagtcg ttttgtctat tgaaaatcta gtggtgaaag
    66421 aaaatcgtgg attagaagcc gtgaaaaact tgaacttaga ggttcgtgct ggcgaagtac
    66481 ttggtatcgc tggaatcgat ggaaacgggc agtcggagtt gatccaagct ttgactggtt
    66541 tgcgaaaggc agaaagcgga catatcaagc taaaagggga agacatcact aataaaaaac
    66601 cccgaaaaat cactgaacat ggtgtaggac acgtgccaga agaccgtcat aaatacgggt
    66661 tagtcctaga tatgacatta tctgaaaata tcgcactaca aacctatcat caaaaacctt
    66721 acagtaaaaa cggcatgctg aattattcag taatgaatga acatgccaga gaattgatcg
    66781 aagaatatga tgttcgaaca acgaatgaac ttgttcccgc aaaagcttta tcaggcggaa
    66841 atcagcaaaa agcaattatc gctcgtgaag tcgaccgaga tcctgatctg ttgattgttg
    66901 caaatccaac tcgtggactg gatgtaggtg cgatcgaatt tattcataaa cgtctgatcg
    66961 aacaaaggga caaatacaaa gcagtgttac tgatcagttt cgaattagaa gaaattttaa
    67021 atgtttcgga tcgtattgct gttatccatg aaggagaaat tgtcggtatc gttgatccga
    67081 aagaaacatc tgaaaatgaa ttaggtctat tgatggcggg ctatacctta gaagaagcac
    67141 gaaaagagtt agaaaagggg gctggcgcac atgaatgatc gcagcgaaaa attccgtaat
    67201 ttattagtgc ctgtactttc agttgtttta ggattgatct taggcgcgat attgatggct
    67261 gcttttggtt ttcagcccat ccaaggttat tcttctatgc tagatgcagc ccttggttcg
    67321 caaagaggga taggtgaaac gttaaggcaa gcaacgccgt tgatttttac agcattaggt
    67381 ttttctgtag ctaactcagc tgggtttttc aatattgggc tttctggaca agcactttgc
    67441 gggtggatcg tcagtgtctg ggtggcactt gcgtttccag atctgccaaa agttgttttg
    67501 cttccgttat gcgtgatctt aggtgcctta gctggtgcga tggcagcggc tgttccaggt
    67561 ttacttcgag cattttttgg aacaagtgaa gtgatcgtaa caatcatgat gaactatatc
    67621 ttattatacg taagcacatt tgctttacat gaagtgatgc ctgaaagcta tcgctcaagt
    67681 ttggactctt ccaatatgat cagtcaaaat gcctcactgc ggttaccatg gttaacacaa
    67741 gcttttggcg gctctcgcgt aaactcagga ttatttttag caatcatcgc gcttattttc
    67801 gtttggctgc tgatgaagaa aacgacttta ggatttgaaa tccgttctgt tggattgaat
    67861 ccttttgctt ctgagtatgc aggaatgagt agtaaacgta cgatcgtttt gtcgatggtc
    67921 atttctggcg ctttggcagg gcttggcggt gtggttgaag gattaggaac gtatcaaaac
    67981 ttctttgttc aaacgacttc gctatctatt ggatttgacg gaatggctgt ttccttgctt
    68041 ggttctggat cagcaatcgg tattctttta tcagcgatct tgttcagtat tttgaagatc
    68101 ggtggacttg gcatgcagac aggagcaggt gttccgtttg agatcgtcaa tgtatcgatt
    68161 gctttgatta tcttctttgt cgggatcaac ttcctgattc gtttcgtcat ggctaaagtc
    68221 ttccaaggga aaaaacaaga agagatcgtt gcgacaatag aatcgaaacc aacgaatcaa
    68281 aaccatgaag ggggcgaact ataatgtcga ctatcgaatt aattgccttg atccttactt
    68341 ctacactggt ttattcaaca ccgctaattc taacgtcact aggcggaact ttttctgaac
    68401 gaagcgggat cgtaaacgta gggctagagg gaatcatggt catgggtgct tttagttcca
    68461 tcgttttcaa cttgacgatg agtccatcac ttggttctat gacaccatgg atcgctattt
    68521 tagtgggtgg cgtcgtaggt atcctatttt ctctgattca cgcagtagca acagtcagtt
    68581 tgcgtgctga ccatattatc agcgggacag taattaatct gatggcacct gctttaggtg
    68641 ttttcttgat caaagcatgg tatggtaaag gtcaaactga taacatcacg cagaatctgg
    68701 ggtatttttc tttcccagga ttagcagata ttccggtcat tggaccaatt ttctttaaaa
    68761 atacattctt acctgcttat tgtgctattt tgattgctgt cctagcttgg gtgatcatct
    68821 tcaagacgaa attcggcttg cgcctccgtt cagttggtga aaatcctcaa gctgccgaca
    68881 cattaggtat caatgtatat gctatgcgtt attcaggcgt actgatttct ggcttgttag
    68941 gcggtatggg cggtgctgtt tttgctcagt cgatttccgg taacttttca gctggtacga
    69001 tcgttggaca agggttcatc tccatggctg ctatgatctt tggtaagtgg aatcctttag
    69061 gggcaatggg tgcctcattg ttctttggtt ttgctcaaag cttgagtatc attggcgcac
    69121 aattaccagt tatttcttcg attccgccag tattgctgca aattgctcca tatttgctga
    69181 caatcattgt gctggttgtt ttcttaggga aagcttctgg tccaaaagca aacgggaaga
    69241 actatatcaa atcaaaataa tcttttagcg aataaaaagg gtgggttacg ggaagtgttt
    69301 ttcgtctcgc cctttttgtt ttaaaggcaa taaaaataaa aagaaagaag gaataatcat
    69361 gtttaaacgc gtacatctga tcgtcatgga ttcagtagga attggagaag caccagatgc
    69421 cgataagttc ggtgatgttg gttctgatac attaggacac attgcgaaag aagcaggatt
    69481 gaacgttcca catttagagc agcttggttt aggaacgatc cgtcctcttg aaggtgtgga
    69541 atcagtgaaa gatcatcaag gctatgcgac gaaattagaa gaagtttctg tagggaaaga
    69601 tacgatgaca ggccactggg aaatcatggg attgaatatc aaaactccat ttcgtgtgtt
    69661 tcctaatgga ttccctgatg atctgatcaa acaaatcgaa gaattttctg gccgtaaagt
    69721 cgtatgtaac aaaccttata gcggaacagc tgttattgac gattacggtg aacaccaaat
    69781 gaaaacaggc gatttaattg tatatacttc tgccgatcct gtccttcaga tcgcggcaca
    69841 tgaagaaatc attcctttag aagaattata tcggatttgc caattcgttc gtgatataac
    69901 aaaagatgat ccgtatatga ttggccgaat cattgcacgt ccgtacgtgg gtgaaccagg
    69961 agacttcaca cgaacaagca atcgccatga ttatgcgttg aatccattcg gacacacagt
    70021 ccttgattct ttgaaagaag caggaaagga cgtgattgct gttggaaaga tcaacgatat
    70081 tttcaacgga caaggaatca ctgaatctgt ccgcacgaaa agcaatatgg atggcgttga
    70141 ccagctgctg aaagttatga aaaacgattt ttcaggaatc agctttacca atttagtaga
    70201 ttttgatgca ttatacggtc atcgtcggga tgtagtcggc tatgcgcatg cgattgaaga
    70261 atttgactta cgaattccag aattgcttga agcgatggaa gaagacgact tgctaatgat
    70321 tacagccgat cacggaaacg atccgacgtt tactggtacc gatcatacgc gagaatatgt
    70381 accgttattg gtttacagta aaaaaatgaa agaacaaggg gcattgcctc aaggatatta
    70441 ttcagatatt tcagcaacga ttgctgagaa ctttagtgtt tcttcgactg aaaatggcga
    70501 aagcttcttg aaattattaa aataatcttt ttaaatagga gaaagcaaat gaccaagtta
    70561 agcgagatgt tacaagaaac gacccagttt atccttgata aaggagtaaa agaaattgat
    70621 tttggtttga ttctaggttc aggattaggt gaattagcag atgaaatcga agatgctgta
    70681 atgatttctt atgatgagat cccgttcttt cctgtttcga cagtagttgg gcatgcagga
    70741 aagctagttt atgggtctct ggcaggcaag aaagtgttag ccatgcaagg gagattccac
    70801 tactatgaag gtcattccat gcaaacagtg acctatccag tacgtgtgat ggccggacta
    70861 ggggcccatt cagtcattgt gactaatgca tgtggtggtg tcaacgaatc atttgtacca
    70921 ggagatttga tgctgattac cgatcatatc aattttactg gtgaaaatcc tttgatcggt
    70981 ccgaatgaag atgcaatggg ccctagattt ccagatatga gtcaagctta tacgcctgac
    71041 tatcaagcaa cagcaaaagc agcagcagaa aaactaggtt tggatcttaa agaaggcgta
    71101 tatatgggct attctggacc aacttatgaa acgcctgcgg agatccgaat gtctcggaca
    71161 ataggagccg atgcagtagg gatgtcgact gttccagaag tcatcgtagc agctcacagc
    71221 ggattaaaag tgttaggaat ctcttgtatt accaacttag cagcaggtat gcaagcgaat
    71281 ctgagccatg aagaagttgt agaaacaact cagagagtca aacaatcttt taaagcattg
    71341 gttaaagaaa cattgacatt attgtaatag gaggaacaat aaaatgagtg tgcatattga
    71401 agcgaaagaa ggcgagatcg ccgataagat tttacttccg ggagatcctt tgcgagctaa
    71461 atatattgcg gagacttttt tggaagatcc agtttgttac aatcaggtac gcggtatgtt
    71521 aggctttacc ggcaaatata aaggagaacg tatttctgtt caaggaacag gaatgggaat
    71581 gccatcagcc accatctatg cccatgaatt gatccagtcg tatggtgtaa agaaattgat
    71641 tcgagtaggt acatgcggtg cattgtcaaa agacgtccat gttcgtgatt tagtactagc
    71701 acaaggtgca gcgaccagtt cttcgatgat cgaaaaaaat ttccaagcct ttcattttcc
    71761 tccaatcagt gatttcaatc tattactgaa agcatatgag atagctaaag aaaagggcta
    71821 tacggttcat gtaggaaatg ttctttcgga agattctttc tacaaagatg atttgacaga
    71881 gacgttccaa ttagctgaac ttggcgtttt aggagtggaa atggaagcag cggctcttta
    71941 ttacttaggc gcgaaatacc atgtgcagac attaagtttg atgaccgtta gcgaccattt
    72001 gatcaccggt gaagaaacaa cagctgcaga acgtcaatct acgttcaatg aaatgatcga
    72061 agtaggattg gaaacagcga tagcagaata agaaggaaat gaaaaagctg ccctgcatta
    72121 agtaataaga acatccaagc aaaaatagct cctcatgttt ttgacttggc tggacttatt
    72181 attgcaaatg taagcttttg aacaccgttt accaagaggt tgtgaatctg ccgtttaact
    72241 ctgagtcaca aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt
    72301 gtgaccgaga agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg
    72361 tgtcacagtc ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt
    72421 catcatttaa ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt
    72481 cgtcagagat accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta
    72541 ctaaaacagt tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag
    72601 cgcgttctaa tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg
    72661 cgtaacgacg gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag
    72721 tatcgtaaga acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt
    72781 ttttgttcaa accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt
    72841 gtggtaccca aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag
    72901 ttaaaacaga agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc
    72961 cttcttttgc ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt
    73021 ggttcaatgc attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta
    73081 gctctccttt taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat
    73141 tttttggaag agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga
    73201 atataaaaaa acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt
    73261 gctcgatttc tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc
    73321 attttgaaga aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt
    73381 tgatcgtttt tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat
    73441 ctaatccaac taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca
    73501 ttaattggaa atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca
    73561 agtgcagccc gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc
    73621 ctaatcgatg aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg
    73681 actccaaatg aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt
    73741 cttgacaacc aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg
    73801 ttgtgcgtgc ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact
    73861 ggatataaca gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt
    73921 tccgctgtct ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt
    73981 caagaatctc aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa
    74041 gcccatgttc tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt
    74101 cgatgacttc tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc
    74161 cgttttcgtc tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct
    74221 gttgggagcc ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta
    74281 atttagaaga atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga
    74341 aaagcaaagc agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac
    74401 cgtctattgt caaatcgact acggggactt catcaatact ctttaacggt attcctaatt
    74461 tttccgcttg ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt
    74521 cacgcatacg gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac
    74581 ctacgatcat cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat
    74641 tcatctttgc gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt
    74701 gatttacggt aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt
    74761 gcatctcttg ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca
    74821 ggtttctgtg aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca
    74881 ttgcatttat tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat
    74941 cgtgggaagg aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa
    75001 atcaaaggtg gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa
    75061 aactcaaact aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat
    75121 gacacctaaa aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt
    75181 aattgaagtt actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt
    75241 attattacgc ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg
    75301 tgctttagat actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa
    75361 aaaacctaaa gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag
    75421 taattactat gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt
    75481 gcaaaacgtg atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc
    75541 aaccgtgtaa tggttgacgg aaaacgcggg attgcagcta acattatcta taatgccttt
    75601 gacttgatca aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa
    75661 aacgttcaac ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta
    75721 ccagttgaag ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac
    75781 gctcgcttgc gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct
    75841 gcaaacaaca caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc
    75901 aaccgtgcgt ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag
    75961 tcgacctcag atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg
    76021 agaatgacca gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc
    76081 gatgctggta aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa
    76141 attggtgaaa ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt
    76201 ggtattacga tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc
    76261 atcgacacac caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt
    76321 gatggtgctg taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt
    76381 tggcgtcaag caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag
    76441 atcggtgctg acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct
    76501 cacccaatcc aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta
    76561 acaatgaagg ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt
    76621 cctgaagaat accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct
    76681 gaaactgatg aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag
    76741 ttaaaagaag gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt
    76801 tcagcattta agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca
    76861 tcaccgttag atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa
    76921 cgtcctgcag acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca
    76981 ttcgtaggtc gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac
    77041 gtacaaaacg caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc
    77101 aactctcgtt cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg
    77161 aaagacacaa ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc
    77221 atggaattcc cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa
    77281 gataaaatgg gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa
    77341 acaaacgtgg aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc
    77401 atcgttgacc gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta
    77461 tcttaccgtg aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct
    77521 ggtggtaaag gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct
    77581 ggtttcgaat ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct
    77641 gttgaaactg gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta
    77701 gatatcaaag ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc
    77761 ttccgtgttg ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc
    77821 cttgaaccaa tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg
    77881 ggtcacgtaa ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa
    77941 caagttgttc gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt
    78001 tctgctactc aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca
    78061 aaatcagtac aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttgaa
    78121 accggatagt cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt
    78181 aaaataatta tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag
    78241 acaaataaaa aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt
    78301 gaccgttcta aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact
    78361 acattaacag ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct
    78421 tacgatcaaa tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct
    78481 cacgttgagt atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg
    78541 gattacgtta aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt
    78601 tctgctgctg acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt
    78661 ggtgttcctt acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta
    78721 ctagaattag ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac
    78781 gatgttcctg tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa
    78841 gaaaaaattc ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac
    78901 aacgacaaac cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact
    78961 gttgctacag gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt
    79021 ggtattgctg aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg
    79081 ttagactacg ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa
    79141 gacatccaac gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc
    79201 tctgcagaag tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact
    79261 aactaccgtc cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca
    79321 gaaggaactg aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac
    79381 ccaatcgcta tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt
    79441 gccggtgtcg ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt
    79501 tattcggacg taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt
    79561 tattgcagga tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag
    79621 agtcagtatt ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct
    79681 tgctttgtga gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac
    79741 agacgtaatc agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc
    79801 tttgccacga acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg
    79861 cgaaggaggg aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca
    79921 ccgtatttta gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag
    79981 cgtgtctggt ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac
    80041 tcataaatac aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga
    80101 cattgtgaac ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg
    80161 tgtaaacatc gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac
    80221 caaaggaatc ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt
    80281 aattccagta actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga
    80341 aacggatggc tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa
    80401 caaacctgcg aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga
    80461 attcaaaaat gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt
    80521 ccaagcagga gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt
    80581 tatcaaacgc cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg
    80641 tcctgggtca atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg
    80701 ccgtatgggt ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga
    80761 aagaaatgtt atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat
    80821 caaatcagct gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa
    80881 tgtagcatta ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat
    80941 cttcggaatt gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc
    81001 attaagacaa ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa
    81061 accatggcgt caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg
    81121 gcgtggaggt ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa
    81181 aaaagttcgt cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt
    81241 ggtagcaatc gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct
    81301 tgctaactta tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc
    81361 tgctttatca gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt
    81421 gctagacgtt gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga
    81481 ggaggtgctt gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa
    81541 tcaatgcttg ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa
    81601 actttagtaa aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc
    81661 gtgaacgtac gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt
    81721 cgcaaagcga tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct
    81781 gaataagcac taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt
    81841 acaaacctac ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa
    81901 catcaacacc tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca
    81961 acggccgcat cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg
    82021 acttcaaacg taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa
    82081 accgttcagc taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag
    82141 cacctaaagg actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag
    82201 tcggaaatgc tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa
    82261 tgaaacctgg taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg
    82321 gtaaagaagg caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag
    82381 ctgcatgccg tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg
    82441 gtaaagctgg acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga
    82501 accctaatga tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac
    82561 cagtttctcc ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat
    82621 cagacaaact tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac
    82681 attttgagag gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc
    82741 atttaatgaa aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt
    82801 ggtcacgccg ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg
    82861 gacgtaaaca tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat
    82921 ttgcacctac aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat
    82981 ttgaggggag gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa
    83041 acagttcgca cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt
    83101 gtcgcagatg caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa
    83161 aaagtattga tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac
    83221 ttggtagtaa gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt
    83281 gcaaaaggat cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca
    83341 gaaaaataag gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg
    83401 catcatccgc gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca
    83461 cgaagattta agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac
    83521 agttgaaatc gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg
    83581 tatggttatt ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt
    83641 aactggtaaa agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa
    83701 attagtaggt gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca
    83761 aaaacaagcc atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc
    83821 tggtcgtcta aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc
    83881 tcttcatact ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg
    83941 aaaactagga gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac
    84001 tgagaaagga gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc
    84061 cgcggaaaaa tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt
    84121 ttgcaagctg ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca
    84181 atgactcgtt acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct
    84241 tatactgcca aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg
    84301 gttgcaccag taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta
    84361 gctcgtgaag cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa
    84421 cgtgaggaaa tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc
    84481 cgaaatgctt gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt
    84541 agcaacaggt caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg
    84601 catcaaaact gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat
    84661 gactgaagga agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga
    84721 taaaacaatt accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat
    84781 gaactattct aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat
    84841 cgtgagaatt atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt
    84901 agtcgaagaa gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa
    84961 atctgaaagg aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa
    85021 ctcaggcgca cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc
    85081 taacatcggt gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa
    85141 aaaaggtgac gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga
    85201 cggttcatat attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc
    85261 tcgtggaaca cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa
    85321 gatcgtttca ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga
    85381 aacagttatg tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa
    85441 caaagaaggc gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt
    85501 aaatgtcgtt aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga
    85561 gatggaagcg ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg
    85621 ccgagttggc tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga
    85681 agttttagat aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga
    85741 aaaatatctt aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat
    85801 gcaaacacct aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa
    85861 cgctaaaaac ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat
    85921 gattacaaaa gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg
    85981 tgcaaaagtt acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt
    86041 ttcactacca cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg
    86101 aaactatact ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt
    86161 agataaagta cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc
    86221 tcgtgagttg ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta
    86281 cgtggctaaa aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc
    86341 ttatactcgt tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg
    86401 ccgtatttgc ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag
    86461 ctggtaaaaa gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca
    86521 attgcagatt ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa
    86581 gtacctgcat caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt
    86641 cgtgatgttg aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt
    86701 ggtaaaaacg gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt
    86761 gcttatgtca aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt
    86821 tcgacttctg aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa
    86881 gttatcgctt acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg
    86941 tatcggaaat aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa
    87001 cgttacagtt aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat
    87061 gaatatcgaa ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac
    87121 aattcatgga acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt
    87181 ccaaaaagcg ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact
    87241 tgtattgaac gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt
    87301 tgaagtacca gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga
    87361 attagctgca aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg
    87421 ttatgttggc gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa
    87481 aattgcatag aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa
    87541 tacattttta cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt
    87601 agtacaataa aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac
    87661 gtcaaaagag acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct
    87721 tgaacgtttt tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg
    87781 taacgctagc aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag
    87841 cagcacaagc tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag
    87901 tagtctttga ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg
    87961 ctcgcgaaaa tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga
    88021 tccaaaacat ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt
    88081 taaaggtgga cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca
    88141 cgtaggattt ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga
    88201 agatgcgaag aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt
    88261 aatcggtgct tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt
    88321 tgctgctggt ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc
    88381 taaatcttta ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa
    88441 acaattgaaa cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat
    88501 cggataagga ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc
    88561 ggacgtcctc aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt
    88621 tcagtggtta agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta
    88681 gtggacgttg aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa
    88741 acctatgaaa cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt
    88801 tggtcgtggt acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa
    88861 agctcgttca ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg
    88921 tcgtttacca aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct
    88981 tgatgtattg aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc
    89041 tggaatcgtg aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa
    89101 gaaattaact gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc
    89161 tggtggatca atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa
    89221 gacattagat cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca
    89281 catattactg taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt
    89341 ttcaacatgt tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg
    89401 ggggtttcac catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg
    89461 cctcgatttg ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg
    89521 actcgatatc tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc
    89581 aatcaatacg ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc
    89641 ggtttgattc taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa
    89701 aaaggtatcg gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct
    89761 gaaagtatca gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg
    89821 aaatctgcta tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta
    89881 acatttttcc aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc
    89941 gcgcctacaa gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc
    90001 tttgctagtt cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc
    90061 ggttctgaaa actggtacaa agtgatgatg gagatcttta actataatac agcacctggt
    90121 gctacgattt atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta
    90181 aaccctgaga aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc
    90241 cctggtaagg ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt
    90301 gcagtcttcc ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt
    90361 ccacaatcaa tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa
    90421 actgcgaaac agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa
    90481 gaaagcgtgt tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac
    90541 aatgaacctc attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat
    90601 cattgatgct tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca
    90661 aaacgaaaca gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc
    90721 tgatgaagta acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg
    90781 cttcttatta gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct
    90841 aaaagatttg aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt
    90901 ggtcgaacgt ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat
    90961 tttcaaccct acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca
    91021 aagagaagat gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag
    91081 tgaaccaatc ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg
    91141 tgaaatcgat gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc
    91201 gtagccgact tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg
    91261 tcagtccgac ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac
    91321 tgcagtttcc gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg
    91381 tggcaaaaga agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa
    91441 tgtttaaagt tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc
    91501 gtatgcatta catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg
    91561 atcttaaccg tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg
    91621 aggtattatc atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat
    91681 tcgtcgtaaa ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca
    91741 aggataattg gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat
    91801 aaacgtgtag tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag
    91861 atcttagctg atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa
    91921 acagatgcta tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa
    91981 gtgaacttga acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc
    92041 cgtggattgc ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca
    92101 gctcgcgcta tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg
    92161 gcagcaaaaa aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca
    92221 catatccatt ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca
    92281 ttagcgtggt catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt
    92341 gccgctcaaa tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact
    92401 gttgaagtaa cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa
    92461 gctacaggtt tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc
    92521 cgccctccaa aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac
    92581 gtcattgaac aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga
    92641 aaaaccaaga atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc
    92701 tcttgaaaga gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc
    92761 tttgccaggt gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac
    92821 catcaaaggt gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct
    92881 gaaaatgtat ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt
    92941 aactgctggc gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat
    93001 ctgtagtgtc tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg
    93061 ttatgttcaa gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga
    93121 ttcaatctac acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca
    93181 ccgtgaagat tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt
    93241 ggaagcaatg agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt
    93301 aactgatgaa gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa
    93361 aatgttggaa atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa
    93421 acgtgcagga atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa
    93481 agtccgtaac ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg
    93541 tttaggttta cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta
    93601 tcgtaaacta ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga
    93661 tttattaatc aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac
    93721 tgcagaaaaa atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc
    93781 ggctttcgta cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga
    93841 atcagcttta caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg
    93901 atacacacgc attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt
    93961 agaacttgtc taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta
    94021 tgatgttgga agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct
    94081 tggggagtaa gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag
    94141 atatgtttga aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt
    94201 tttgatagtg ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg
    94261 aattagaaaa gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg
    94321 tctcctttac aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa
    94381 aatcgacact tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag
    94441 tgggaaatca aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatgg
    94501 tttttcaaaa tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg
    94561 gtcttgaaaa tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg
    94621 agaaagttag aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa
    94681 aacaacgtgt tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg
    94741 aagcaaccag tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga
    94801 tcaaagaaga aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta
    94861 atgccaatcg gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag
    94921 aaattttttc tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa
    94981 aactgaagag cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag
    95041 aaaggatggt ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc
    95101 gaatacacca tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag
    95161 ttatactgca ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa
    95221 tgcgcttgtt aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga
    95281 tacggataat aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc
    95341 agaagcacag ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt
    95401 tggtgtcagc gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct
    95461 ggatgaaagc tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt
    95521 agcaatcgct ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc
    95581 aggacttgat ccccagggca gaaaagaaat gatggagatg ttttggcgtc ttcataagga
    95641 acagcagatc actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga
    95701 ttatgtctat gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt
    95761 tcaaaacatt gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc
    95821 agaagaatta atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt
    95881 agcagacgct atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg
    95941 gtcgttatat gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag
    96001 ccagttttta ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt
    96061 tggcattttt cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc
    96121 gaggcattcg cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta
    96181 caagtggcgg agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga
    96241 tgaacggcct ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca
    96301 cgcttactac accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga
    96361 aagccgtacg gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg
    96421 tgcctacatt gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg
    96481 attttggtga aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt
    96541 tatttgtcag cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct
    96601 acaaaggtgg ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga
    96661 tggttatcat tgcttttgta ttattaactg tgctactgat ctttttaaga ggataaacgt
    96721 tcagtgggcc gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcaagcag
    96781 tgtatgacaa gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat
    96841 ctgaaaagaa agaacgaaaa aattttatag aaaaatcatt attccagata accttttagg
    96901 aacaaaggag agaaaaacat ggtacgttac aaagcaatca ttgcgtacga cggaacaaat
    96961 tttaatggat tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca
    97021 ttacaaaaaa tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc
    97081 ggagtacatg cgatcgggca agtaatccat tttgattatc cagaggagcg tccgttagaa
    97141 cgaatgcgtt tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa
    97201 attgtttcag aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga
    97261 gtggatatag ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac
    97321 ccacttgatt tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc
    97381 acctcttttt gtgcatcagg aagctcgata gaggataaaa tacgtacgat ctacgaggct
    97441 aagatggagg taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc
    97501 ttgtataaga tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg
    97561 cctgaagata gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca
    97621 gcacaccctg aaggacttta tttgtatgaa gtgaaatatg aataagaggt tatgatagaa
    97681 gtggtcagct tcaagaaata agaaggtatt tacgaaaatt acttctcaaa attttgcaaa
    97741 atttcggctt attttcgaag aagctacttc tggaacaccg tttaaggaag aggtcgtgaa
    97801 atcagcgttt tgacctgagt attagagaaa caaacgggaa aatagctcct catattttgc
    97861 cgtttgttga gctaataccg aaggtcagct gattgaacac cgtttaagaa agaggtcgtg
    97921 agcctgtcat ttaactctga gtcacaaaga gcaatttcaa aaaacagctt ctcatctttg
    97981 atgaatatcg tgacttgtgg acgaggcgtt gataagtgaa tcatcttttt gttacctatt
    98041 ttttctgtaa ccaaaaaacg atggaacgtt gttttgattg cccttggtgc ggacagtctg
    98101 aacaggttcc atcgtttctt tattttctac gtcttcttct gtgtgtgttt cgtggttgtt
    98161 cttctattgc tggatcaatc gtgccataaa aggggcgatt gcggtcaagg taccagacat
    98221 aaagaataaa caatgcaata cataggacaa aaaggattgc acctatcgta aatccttcag
    98281 gcaagtaact gaaagtgaca gtatgtttac ctgctggaac ttttatcatc aagaatgcgt
    98341 ctttgaaatt gctgaccttg actggtttcc catcaatttt agctttccat cctttgtcat
    98401 aaggaatagt tgtcaccaac atggaatctt cagcggtatt tacagtccca gaagcttttc
    98461 tgccagtggc ttccatttcg acaccttttt ctttgatctg attcattgcg gcttgatagg
    98521 ctacaacatc tagaccaacg actttaggct ccatgaaact tatttctttc gtcccataaa
    98581 aacttgcagt aaatgtcact gttgtctctt gaggataata gccaagatca tagtattgac
    98641 cagaaatgtt gatttgcgtt tttcgcgatg taccattgac agtgatcgtc gcactagaac
    98701 tttctaattg cgcaaaattg gttgggaaca aacttaagta agcttgtgta tttgcaggca
    98761 catggacttc ccaagtgagc tcttttggct ggttatctgc tgtttctgag taagtgacgc
    98821 cagtcgttgt ctttgtgatc gtcgtattca actgattctt caaagtaggt gtatagaatg
    98881 taaaatactg ttcatttaga ccagacaatg tattgatcaa gtttgtctga ctggtcaaat
    98941 tatctgtcac tggctgctca acatcattaa cggacaacgg tgcagtaaat gctagtggca
    99001 atgcattgac attctgatac agtgtatagt cgccgctttg accagcttgg cggaagccat
    99061 atttactgaa cgtgctttcg tttttagaaa tgttatattt gattcctgta aacccatcca
    99121 tcagcaaagt attattgtta taacggatat tcaaatttgt ccctcttgaa cggaaaccta
    99181 atttatccag gtaagaggaa gaattacgat ttcttataga agaaaacaaa ctgataccac
    99241 tgtaaccata gttgatcgaa tcgtttgcag atactggatc cagattttcc aagcggtaaa
    99301 acgagtcgga atcttttttt gtttcattta caagagcttt caagtcagga taaggatcag
    99361 tatataaact gcgggaagca taattccaat catcaagaat gccatggatc atactgttcg
    99421 tattgaccag tgcttcagca gacatgatca ataataacaa tatactcaga tgattgaatg
    99481 aaagtttttt atgctgataa aatcccacag caaaagcata aatccctaag aaaaccactg
    99541 tcaatacaaa ggaagtcatc gtcacatagg tgtagcttcc ttcaggtttg atgccccatg
    99601 ccaccgcaaa gagagcagct acgaccaaaa tgattcctaa caacagccca cgatcgtctt
    99661 gttctatctt ttcccatcct tttcctgcaa gcaggagcac taagaaagag aacagatagg
    99721 cataacggaa taaaaacata ttcggtgcat gcataccatg ccagaacaaa ttcaatggaa
    99781 caagataaaa acttgcgata agtatggcga aaagactgcc gtacaaaaat ttatttttca
    99841 acggtacttt ccgactggca aaataaaaca gacagaggac taatggtagc agacctgcgt
    99901 aaacgaacgg aatcgatccg tattttgtcg tgtcataaac accaatcata tttttcatga
    99961 ttagatccag ataagaagtc gcttctgttt tcaacgtagt gatctgactc agtgcctcgc
   100021 catttgaccg aagatccagc actgctggca atacaatgat cattgaagcg ccgcctgcca
   100081 gtaaagaagt gataccataa ggaacaatcg tttttttata ttctgaccag tttgtcaata
   100141 gacgggcgat aaaatataag aaagaaaata cgccaatcat aaaacccata taaaaactgg
   100201 ataaaaacaa gagtaaataa ctgataaata aaagtttcgg ccgtttaaga tccataacac
   100261 gatgaatccc caaaatcact aatggaagat aaaaaaatgc atccagccac atgatgatct
   100321 ccgaatgtgc agtgataaat gagatcaatg cgtaactgac gctaagtgca acatgccccc
   100381 agcgaggaat cttgaacgta cgtgcaagaa accaaaaagc caatccggca cagccgacct
   100441 taagcaaagt cagaacatac agtgcatctg gcatcatctg gtttggaaaa aagaacacca
   100501 gtggcgtgaa gatcccgcct agatagtaag aaattaaaga taaataattc aatcctagag
   100561 aagcattcca tgtataaaaa atactttgct ttccaagaag aacatttcgg aagctggcat
   100621 gaaaattaga aaactgtgaa aaggcatcac ttgccaaaat acttctgctg cttccaggat
   100681 agattccgat acttagataa acaagtgcta aaatcaaaaa cggaatcagg aaactagctg
   100741 ctgcgtagcg tccgttttct ctaaagaatg actttaaatt ttttttcata tttattttcc
   100801 accaaatttc tatgaagttg tattcagttt atcatatcct tgtttttctc tgcttaaaaa
   100861 gagtctagtt ttcacaaaaa aataaaattt agaataaata acttcataat ttgttcgtat
   100921 aacaaaaata aacgcaaaaa aagggtagga atcaaaagtc ccacccttaa aaatttttat
   100981 taaataaaaa accgttcact atctgaacgg tccaagtatc attcaattaa acgcgttcaa
   101041 cttttcctga tttcaaagca cgagttgaca cccaaacttt tttaggtttt ccgtcgacca
   101101 taacgcgaac tttttgtaag ttaggtttaa cagtacgttt tgttgagttc atagcgtgtg
   101161 aacggttgtt tccacttttt gtcttgcgac ctgtaaagta acaaactttt gccatggtaa
   101221 tttcctcctt tgccttgatt tggagcaata gaataattca gctcatacca gactaacata
   101281 tcatatagaa tgggaatttg caagtacatt ttcatagata caattgacaa ttgagaagaa
   101341 taattgtaaa ttaaacaagg ttatacctga aattttgcaa ggtttttgag tactttgggt
   101401 aactgccttt tatttcaagt tgcgctatga taaaatatga tagaagaaaa atgggagttt
   101461 tttacccgtt aaggaggctc attcatggct gtaaaaattc aaacgtcagc tggaaccatt
   101521 gaaattacca atgatgtaat tgcaacagtt gttggtggcg ccgcgacaga tgtgttcggt
   101581 gttgtaggaa tggccagcaa aaatcaaatt aaagataata ttactgagat tttgcgtaaa
   101641 gaaaattact caagaggagt agttgtccgc caagaagata atggtattgc tgtagatgtt
   101701 tatacgatta tcagctatgg tacgaaaatc tctgaagttt cccgcaacgt ccaagaaaaa
   101761 gtgaaataca atctagaggc attattaggc gtaactgcca attcagttaa tgtctttgta
   101821 caaggtgttc gtgtactgcc agactaggca ggagactggc tggtaactca gcagtcgatc
   101881 tgaaggagga ttatctaggt gagtgtaaca gaaataagtg caagccagtt ccaggaaatg
   101941 gtccaggcag gtgcgaatcg tctgcaagta aatgcagaat acgtcaattc attaaatgta
   102001 ttccctgtgc cagatggcga tacgggaaca aatatgaatc tatctatgac tagtggagct
   102061 aaggcagtag tagattcaac ctcagaaaaa gtaggagaat tagcagcaat gctttcaaaa
   102121 ggattgctga tgggtgcgcg cggaaattcc ggcgttattt tgtctcaatt gtttcgtgga
   102181 ttttctaagc aaattccaga tgttgtctca ttaaatgctt ctgatcttgc tgcagccttc
   102241 actcatggag ttgaaactgc gtataaagca gtaatgaaac cagtagaagg aacgattttg
   102301 acagtagcta gagaagcagc gaaagctgga gaaaagaaag caaaaagtac tgatgatgtc
   102361 gttgaagtaa tgacagctgt tgtaaaagga gcaaagcgtg ctttagctaa aactccagac
   102421 ttgcttccag tcctaaaaga agtcggtgtc gtagacagtg gagggcaagg actgctgttt
   102481 gtttatgagg gctttttaag tgcattgaat ggagaattcc aagcggatga aacatatgaa
   102541 ccttctccag cagaaatgga tgatatggtc aatgcagaac atcatcgcag tgtccaaggt
   102601 caaatggcga cagaagatat ccattttggt tactgtacag aaatcatggt aaaaatcgga
   102661 gaaggaccta cagtcgatag tacattcgat tacgaagaat tccgtaacta tttagatggt
   102721 ataggagatt ctttacttgt ggtcaatgat gacgagatca tcaaagtcca cgtgcataca
   102781 gaaaacccag gagaagtctt gaattatgga caaaaattcg gttcattagt caaaatcaaa
   102841 gtcgacaaca tgcgcttgca gcatgagacg attttggaac acgatgaaga agtgaacgag
   102901 tttgcgaaaa aagaaatacc acgtatcccg tatggtatcg tagcgatcgc tgctggtaaa
   102961 ggcgtccaag agctgtttga aagtttaggc gctaattatg ttatcagtgg tggacaaaca
   103021 atgaatccaa gtacggaaga cattgttaaa gcgattcaag aagtaaacgc agataaagtg
   103081 attgtcttgc caaacaataa gaacatcttc atggcagctg atcaagcagc agaagtagca
   103141 gatatcccag tagcagttgt tccttcaaga acgatttccc aaggattgac agctatgctt
   103201 tcattcaatg atcaagcttc tttagaagaa aacaaagaaa cgatgacaga aatgttgtct
   103261 agcgttgtga gcggtcaagt cactcacgcg atcagagata cctcaattga cggtgtagag
   103321 atcaaagaag gagacttttt gggcatgatc gatggaaaaa tcctgatctc taacccagat
   103381 atcacagcaa cagcgttaag tacactagaa caaatgatca atgaggacac agagatcgta
   103441 acgatcttgg caggtgatga aggaacagtt gaacaagcaa atgaatttgc tgagaaacta
   103501 acagaaaaac atcctgattt ggaaatcgag atccaccaag gagatcagcc tgtctatcct
   103561 tatctatttt ctgctgaata atttctgtgt cagaatatct ttctaacaca gtattcattc
   103621 ataaaaggcc ttcggttagt gatcaggtat gatcgctgac caagtccttt ttttgttaaa
   103681 ggagggagga aaaatttatg cgttctttag atgatccaat cactatgctg gcaggagtcg
   103741 gagaaaaaag agcagctagt cttgccagct tgggcatcca aacgattgaa gacttactga
   103801 cttattatcc ttttcgctac gaagatattc aggaaagaaa tctaaacgag atccaggatc
   103861 aagaaaaggt tactttgaaa ggaatcgtag tctcgcctcc tgtgatgaat cgatttggtt
   103921 ataaaaaaag ccgattgcaa tttcgtatga tgcaagaaca tgatgtgttc aacgtttctt
   103981 tttttaatca accttatcta aaagaaaaag tcattttatc ggaggaaatc gccgtatacg
   104041 gtaaatggga tgcaaagcgt aaagccttga acgggatgaa gattttaggt tctcaaacaa
   104101 tggatgactt ttcgccgata tatcacgtca acaaatcaat tcgtcaaacg acattagttg
   104161 atctaatcaa aaaagggttt caagaatacg gcacattgat tgaagaaaat ctgccaaaca
   104221 accttgtgga gaaatatcga ctgcttgacc gagcttctgc tgtaagaagt atgcattttc
   104281 caaaagacca cgaagaaaac catcaagcca aacgacgtgt cgtttttgaa gagttctttt
   104341 tatttcaaat gcgtcttcaa ggattgaaaa aagcagaaaa agcagaaacg aatggtttgg
   104401 agatccttta tgatgtccaa aaattgaaac aatttactca aaagctacct tttgaactga
   104461 caaatgcaca aaaacgtgta acgaatgaaa tctgtcggga tcttcgcagt ccgcagcata
   104521 tgcagcgact tttgcaggga gatgtaggta gcggaaaaac agtggttgcc gcgattgcgt
   104581 tatacgctac cgttacagca ggtttccaag gtgcgttgat ggtgcctaca gaaatcttgg
   104641 cacaacaaca tatggaaagc ttgcaacagc tgtttgatcc caatgaagta accatcgcat
   104701 tgattacggg gtcaacgaaa gcaaaagaac gacgtgagct ccttgaaaaa ctagagcaag
   104761 gggaaattaa cgtcgtgatc ggcacacatg cattgatcca agatggagtc gaatttcaga
   104821 atttaggtct agttattacg gatgagcagc accgttttgg cgtgaaccag cggaaagtac
   104881 ttcgtgaaaa aggctggcga ccagatgtct tatttatgac agcgactccg attcctagaa
   104941 cattagctat tacagcatat ggtgagatgg atgtatctat cattgatgaa cttccagctg
   105001 gacgtatccc gatcgaaaca cgctgggtaa gaacacctca attggacagt gtactggatt
   105061 ggacgaaaaa agaactggca agaggacatc aaatgtatgt catctgtccg ctgattgaag
   105121 aatcagaagc attagatgta aaaaatgcag tggaaatcta tgaaaaactt cgtgaactat
   105181 ttgcaccaaa atatgaagtt ggcttgttac atggtaaaat gaagaatcag gaaaaagaag
   105241 taatcatgga agccttcaaa gacaaccaga tgcagatatt agtttcgact actgtaattg
   105301 aagtaggggt aaacgtgccg aacgcgaccg tcatgctgat catggatgcg gatcgatttg
   105361 gattggcaca gctgcaccaa cttcgtggac gtgttggacg cggaagtgat gcttcctact
   105421 gtatcttagt tgctaatcct aaaaatgaac taggtgtgga acggatgaaa atcatgacag
   105481 agaccaccaa tggttttgta ctaagcgaaa aagatctgga attacgtggt cctggtgaag
   105541 tatttggctt ccgtcaatct ggtctgcctc aatttgcgat tgctgacttg gtgacggatg
   105601 gaaatgtttt ggaggtagcc agagaagagg ctgcagccct ttggcaaata aaggattggc
   105661 agatgcttcc tgagtatcag cctttagcgc aaagcctcca aatagaaaat caggataatc
   105721 gttatttcga ttagcagact gtgctatact ttatactgat gacggaaaaa ggagtggaaa
   105781 caatgaaaat tgccgtagat gcaatgggcg gagatcacgc acctcaagca attgtagaag
   105841 gcgtggcttt agcgcagcaa gattttccag aagtagaatt cttactttac ggaaaagaag
   105901 cagaaatcaa gaaatactta acaaatgaaa aaaacatcac gattatccat acagacgaaa
   105961 aaatcaatag tgatgatgag ccagtaaaag caattcgacg aaaaaagact gcatcaatgg
   106021 tccttgctgc acaagcagtg aaaaacggtg aagcagatgc tgtattttca gcagggaata
   106081 caggcgcgct actagcagca gggttgttca tcgtaggacg tatcaaaaat atcgaacgcc
   106141 ctggcttgat gtctaccttg ccagtagtag ggaaagaagg tgccggtttc gatatgctgg
   106201 atcttggcgc taacgcagaa aacaaaccag aacatttgtt gcaatacggt attttaggtt
   106261 ctttttatgc acgtaaagtc cgaggtatcg gacgtcctcg tgtcgcactc ttaaacaacg
   106321 gaacagaagc aacaaaaggt agtgaagtga cgaaaaaagc ctatgaactc cttcagaatg
   106381 aaacaagctt gaattttatt ggaaacgtag aagctcgtga gctactcaat ggtgtggctg
   106441 atgtagtggt cacagatgga tttacaggca acgctgtttt gaaatctatt gaaggaacag
   106501 caatgaatat gatgaatcta ttaaaatctg ctattctaaa tgaagggatc aaaggaaaaa
   106561 tgggcgctat gcttttaaaa gacggcttac gttctttgaa agcagaaatg gattattcca
   106621 aacatggcgg tgccgttttg tttggcttga aagcaccagt cattaaaact catggagcaa
   106681 caggccccga tgctgttcgc tatacgatcc gccaaatcca cacaatgctt gagacagatg
   106741 tagttggaca attagtcgaa caatttgaaa aaagcgaaga atagtatttg gatatctgaa
   106801 gcgatccgtt ccattgaaaa aaaggtggac attcctgaaa aatgccagta aaattagcca
   106861 tggtgtaggt aattgacaag tgtatgattc ttggaggtga aaaagttgac tcgcgaagaa
   106921 gtatttaaca aagtagcgaa aattatttca aatcattttg agatagatac cgataaagtg
   106981 acggatgaat tgaacatcaa agatgattta aaagctgatt caattagtat tatggaattc
   107041 gttttagagc ttgaagatga attcggtacg gaaatttcag atgaagacgc tgaacaaatt
   107101 gaaacagtcg gtggcgcagt agattatatc agcagccatc ttaaataatt tcaaataaaa
   107161 gcaaagaagg ataaaaagct gcatgcagct ttttatcctt ctttttttaa tctttttgac
   107221 acgtaaaagt catttttctg ataattctgg cgataaacag aaattatgtt gcaaagtaaa
   107281 gcggttttct atataattat taataattca ttacacaaag ataagaataa cctttgttat
   107341 aaaacgattt attctgtgta atgtcctttt ttattaagaa aaacttccat ttaggaagca
   107401 gagaggggta ttcgattgtc cgataaccaa ttattagaag ttcagaacct acatacagga
   107461 ttccgactca aagatgacta ttacgatgca gtagatgacg tttcatttac tttagacaaa
   107521 aacgagattt tagcaatcgt tggggaatct gggtgcggga aaagtacctt ggctactacg
   107581 attatgggat tacttgatcc taataacaca aaaattacag gtgagatttt atataacgat
   107641 ctgaatttaa tcgacctgaa cgaaacgctc tataataaaa tccgcggaaa tgatatcgga
   107701 atgattttcc aagatccgtt gtctgcatta aatcctctca tgagaatcga agaccagatc
   107761 aaagaaggac tttcctatca cacaaagatg aatgcagaac agcgtcaagc tcgtgcacta
   107821 gaattgctag aacaagtagg gattcctaat cctgcgagag ttggacgcca atatccccat
   107881 gaactatcag gcggtatgag acaacgtgtc atcatcgcaa tcgcaatcgc ctgcaaacct
   107941 ccaatcgtca ttgcagatga accgacgaca gccctagatg taaccatcca agcacagatt
   108001 cttgatttac tgaaagacct tcaggaagaa acaaaaacag ggatcatctt gatcactcat
   108061 gacttaggag tcgtagcaga aatggctgat cgagtggcag tgatgtatgg cggacagttc
   108121 gttgaagtag caggtgtaaa agaactgttt gatcatccta agcatcctta tacacgctct
   108181 ttactgaact ctataccaca agaaggaaat catgatgcag aactccatgt gatcgaaggt
   108241 gtcgttcctt ctctgaaaaa catgcctcgt aaaggttgtc ggtttgcacc acgtattcca
   108301 tggataccag caagcgatca tgaagaagag cctatccttc atgaagtcgc accgaaccac
   108361 ttggtacgtt gctcctgcta taagcatttc cactttagag acgaaaaagg agaggtgtag
   108421 atgacagaat taatcacaat caaagacctg aaagttcatt accctattcg cagtggattc
   108481 ttcaatcgag taacggatca tgtatatgct gtagatggtg tggattttat tatcgaaaaa
   108541 ggaaagacat atggtttagt gggagagtct ggctctggaa aatctactac gggaaaagcc
   108601 gttgtgggat tagaaaaggt aacagccgga caaatcatgt atgaaggaaa agatgtaacg
   108661 aagcgaagca accgcaaaaa aatgggttat aacaaggatg tgcagatgat cttccaagat
   108721 tcaatgtcca gtttgaatcc taaaaagcga gtgttggata tcattgctga acccatccga
   108781 aattttgaac ggttaagcga tcaagaagaa aagaaaaagg taaaaggact gctagatatc
   108841 gttgggatgc cggaagatgc gctatataaa tatcctcatg aattttcagg cggacaacgt
   108901 caacgtctag gagtagcccg tgctgttgct accaatccaa aactgatcgt agccgatgaa
   108961 cctgtatctg ctctggatct atctgttcaa gcgcaagtat tgaatttcat gaaacgaatc
   109021 cagcaagaat acggcctcag ctatttattc atttcacatg atttaggtgt agtaaaacac
   109081 atgtgcgaca atatcgcaat tatgtacaaa ggtcgatttg tagaaatcgg tacaagagaa
   109141 gacatttata atgacccgcg acatatctat acgaaacgtc tgctttcagc tattccgcaa
   109201 atcgatgtag aaaataggga aagccacaaa gaaaatcgac gaagagtaga acaagagtat
   109261 atccaaaacc aaaaagaata ctatgatgcg actggtcgag tctacgattt gcgtacgatc
   109321 acaactacac acaaagtggc gttgaaagat ggaggtgcaa gctaatgtgg aaaacgattc
   109381 tgcgacgtgt tttattgatg atcccgcaag ttattatttt aagtgttctg atcttcttat
   109441 tagcccaagc gatgccgggg gatccattta ccggtttgat caatccaaat caggatccgg
   109501 cagtgatcga acagatgcga caagcagctg gcttgaatga cccatggtat gtccagtact
   109561 tccgttggat cggaaatgct ttgcaaggcg attttggtca aagtttctta tacaaacgct
   109621 ctgttgctga cttgatcggc gaacggatca tcaacacttt atatctatcg atcttgacag
   109681 ttgtccttac ttatttgatt gctgtgcctc tggggatgct tgctggccgg tatcaaaatt
   109741 caatcttgga taagattgtc gtaatctaca acttctttag ttttgctgtt cctttattta
   109801 tcttcggctt gatcatgcta tttgtttttg gttatcgttt aggctggttc ccaacaagtg
   109861 gatcacaaac actaggtttg caaggtggat ttatcactca atggatagac cgtttgaaat
   109921 atattctgtt accatcaatt acccaagcat ttttggcgac tgccgtcaca atccaatatc
   109981 tgcgaagtga agtaatcgat tcgaaatcgc tcgattttgt cagaacagcc cgttccaaag
   110041 gggtaccgac gaataaagta ttcagtcgac atattttccg aaatgcagcg ttgccgatgg
   110101 cttctcaaat ggggtatgaa atcacttcgt tgattgctgg ttctgtagtt atcgaaaaga
   110161 tttttggtta tccgggagtc ggaaaactat ttattgattc catcggccaa cgggactata
   110221 ccgtgatcac atccttagta ttgattttag gaatcgcgac gctagtgggg acattacttt
   110281 cagatatcat catgagtatc gttgacccgc gtattcggat tcaataaaac caatcagaaa
   110341 ggagaatgga tcgatgagtg aaaaaaacaa tacagcagtt caagaaagta ttcctcctat
   110401 ggggatacga atgattgctc gagaatttaa aaaagataaa attgctattt tttcattagg
   110461 tttgctagtg gttttattat tagtgatctt tatcggtgcg atgctgaccg atcaagacaa
   110521 agtgatgtat gttagtatct tcgacaaata cgctgcacca ggaacagttt cgacacaagg
   110581 acaaaagttc attctgggag cagatgaagg cggacgtgat gtattaggac aattgatcat
   110641 aggtgctaga aactctgtta cgatcggatt tgcgatcacg atccttactt cgatcatcgg
   110701 ggttggatta gggatcatct ctggctacta cggagggatc attgacaaca tcttgatgcg
   110761 gatcgttgat tttatcatga ttctaccgat catgctgatc attatcgtct tcgtatcgat
   110821 tatttccaga tacaatgtct ggtcctttat attcatcatg agtgcatttt attgggtagc
   110881 taaagcccga ttattccgaa gcaagacatt atctgaagca agaagagatt atgtcagtgc
   110941 ctcaaaaaca atgggaacca atgattttaa aatcatgttc cgcgaaatca tgccgaatct
   111001 aagttcatta atcattacta atttgacgat gaactttgcg gcaaacatcg gtatcgagac
   111061 aactttgact ttcttaggtt tcggcttgcc ggcaaatgta cctagtttag gtacattgat
   111121 cggttatgca agtaacggag aagtcttagt gaatcggcaa tggatctggt tacccgcatc
   111181 aatccttatt ttagttttga tgttgagtat caattatgtt ggacaagcat tcaagcgttc
   111241 tgcagatgcg cgccaacggt taggctagta tagaagcgaa gggggaaata ggaatgaaga
   111301 aaacgatttt tggatttgca gcgctgatgt ctgctgtcgt tcttgcagca tgcgggggcg
   111361 gaggtacaga tacctctgga aacaactctg gaggcaacgg caataacaaa gaggaattaa
   111421 cttttccaat tgcaacaaaa aataatgatg atgcaatcga agacggcgaa ttagaagctg
   111481 cggtcgcaac ggacagtcag tttaaaggat tgttccagtg ggagttttac caagattcat
   111541 atgatgcagc ttttatggct ccttctcatg aaccgctatt tgcaaacgat gacgatttca
   111601 gaatcacaga cgacggagct gcaacgcttg atctagatga agatacgaaa aaagcgacaa
   111661 tcaaagtaaa agacaacgtc aaatggtcag atggtgaaga tgtaacggcg gacgatgtga
   111721 ttttccctta cgaaatcatt gggaataaag attacactgg tatccgttat gacgacactt
   111781 tccgtaacat cgtaggtatg gaagaatatc atgatggaag tgccgacaca atctccggaa
   111841 tcaaaaaaat agacgacaaa acagttgaaa tcgaatataa agaagtaaac ccaagcatgc
   111901 ttcaatcggg tggtggtatc tggtcatatg cagcaccaaa acatacgtta gaaggtgtag
   111961 caatcaaaga tatggaatca agcgatcaag tacgtaaaaa tccagtgact tttggccctt
   112021 attacatgag taatatcgtt gcaggagaat cagtagaata cttgccaaac gagcactact
   112081 ggaatggtac gcctaaattg aaaaagatca cgatgaaatc tgtaccgatg gcaagtgcaa
   112141 ctgaagcatt gaactctaaa ttatatgata tgattttcca aatgccaaca gatacttacg
   112201 atacctataa agaaattgct ggctatacaa acttaggccg tgaacaaact tcttatactt
   112261 atctaggatt caagttaggt aaatggaatg cagatacaaa gagtgtggaa tacaatccag
   112321 attcaaaaat ggctgataaa tcattacgtc aagcaatggg ctatgcatta gataataatg
   112381 cagtaggtga acgtttctat gcaggtttga gaagcaatgc gacttcattg attcctccag
   112441 tattccagtc ataccatgat gatgagatga aaggattcac acaagatcta gacaaagcga
   112501 aaaaactatt agatgatgct ggctacaaag atgtggatga cgatggttta agagaagaca
   112561 aagatggaaa taaactaaca atcaactttg cttcgatgtc cggtggggaa acagcgcaac
   112621 cattggcaga ttactatatc caacaatgga aagaaattgg tttggatgtc caatacacaa
   112681 caggtcgtct gatcgaattc aattctttct atgataaatt agaaaacgat gatcctgaaa
   112741 ttgatgttta ccaagctgct tggaatacag gaactgatcc aaatccaagt ggactatggg
   112801 gaccaaatgc tgcgttcaac tacactcgtt atgaatcaga agaaaataca aaattgatca
   112861 acgatatcag ttcaagcaaa gcatttgatg aagagtacca aaaagaagca tatcaaaaat
   112921 ggcaacaata tgcatttgaa gaagcatttg cgattccaac gttgttccgt aatgaagtat
   112981 tgccagtcaa cgaccgtgtc aaagactggg attggtctta tgatgtacca aacccatggg
   113041 caaatgtttc tgttacagca gattcacgtt cataatcact aaaaatgacc gaaaaagggc
   113101 gatgtccttt ttcggttttt tgatattttt ctgtttattt ctctaatatt caggtcaagg
   113161 cgctgatttc atgacttctc caataaacgg tgttcaaagt ccagtttctc ggtattaagt
   113221 caaatttatg caaaaatatg gaaagccatt ttcacaaaat tttttcttca tactcgaaac
   113281 taaacgaatt tttcacaact tctcgtcaat cactaggatt attaaagctt tacttacctt
   113341 ttgaccgaac catttcaaat ttgacaaaaa accagtataa taaggaagta tcgaaaaaat
   113401 atccataaaa ggaatgtgga aaatggacaa ccagctgaca aaagaactaa aagaaaacta
   113461 taacatcgtt tttcacgatc taaatttgct tgaacaagct tttacccatt catcctatgt
   113521 gaatgagcat cgcaatctgc aattatcgga taatgagcga cttgaatttt taggagatgc
   113581 cgttttagaa ctgatggttt ctcagtattt attccgttta tatcctcatt tgccagaagg
   113641 aaaattgaca aaaacacgag ctgcgatcgt tcgcgaagac agcttgtcga aatttgccaa
   113701 agaatgtcac tttgatcaat atgttttgtt gggcaaggga gaagagaatt caggaggacg
   113761 tacgcgacca gcattgcttt gcgacctatt cgaagctttt ttaggcgcgt tatatcttga
   113821 ccagggattc gacacgaccc atgcattcat cgaaaaagtg atttttccta aagtcaaagc
   113881 aggtgctttt tcacatgaga tggatcataa aacaaaacta caagaagtct tgcaaaaatc
   113941 aggtgatgta tcaatcgaat accgattgat caatgaagaa ggtccagctc atgaacgagt
   114001 attttggatc gaagtttatg tagatgatca attgattggc actggacaag ggaaatcgaa
   114061 aaaattagca gaacaagctg cggcggaaaa tgcattggca gcactgtaaa agtaagtgag
   114121 ggaaagcttt gtatttgaaa cgaattgaaa tagccggttt taaatcattt gcagacaaga
   114181 cagtcattga ttttgaaaat agcgtcacag cagtggttgg accaaatggc agcggaaaaa
   114241 gcaatattac agaggctatc cgctgggtat taggagaaca atctgctaaa agtctgcgag
   114301 gcggaaaaat gccggatatc atctttgccg gttccgatac ccgtaagcag ctgaatattg
   114361 cagaagtcac agtgatttta gacaatagtg atcattatct gccattggag tacaatgaga
   114421 tcagtgtaac ccgccgttat cgacggactg gggaaagcga gtttttcatc aataaacaaa
   114481 gctgcagatt aaaagatatc caagaattgt tcttagattc tggattagga aaagaatcgt
   114541 tctcaatcat ttctcaagga aaagtagaag cgattttcag tagtaaaccg gaagaccgtc
   114601 gtgggatctt tgaagaagca gctggtgtct tgaaatacaa gcagcggaaa aagaaagcag
   114661 aacagaagct ttttgaaaca gaagacaacc tcagccgcgt ccaagacatc atccacgaat
   114721 tggaagaaca gttaactcct ttggccgccc agagtgaggc agcaaaggag tttttacggc
   114781 taaaagaaac actgactcaa accgatgtct ctttgatggt tgctgaaatc aagacagcaa
   114841 aaaaagattg ggacaacaaa caagcacagc ttgcgaaatt caatctagaa ttaggcaaac
   114901 tatctgagtc gatccaagaa caagaatcca ttttggcgaa gcagcgtaaa gaaaatgcgc
   114961 aagccgatcg tctgatcgaa aaaaatcagc aagtattatt agatctttcg gaaaaactga
   115021 agcagacaga aggacaaaaa gatgttttgc aggagcggac aaagcataca caaaaaagct
   115081 cgcaagaata tcaaacttca ttagcagaag cacaaaaaaa ggttaaacat tttgaaaagc
   115141 ttcaagaaag cttgatgaaa gcagcagcag aaaaagaaac agagatccaa aaagctgaag
   115201 caaatctcat aaaaacacag caagaattag aaaaatacca aaaatcaacg aaagaattat
   115261 tggcagaatt aagagatcaa tatgttgatt tgatgcaaga acaagcagct gtaggaaacg
   115321 aactgaagta tctagaacgt caatatatac aagaaacagc aaaaagcaag cagacgttag
   115381 ccaagcaatc ggaagtagaa gcatcagtag accgattgat cttacaaaaa gaagaattga
   115441 cacaaaagca ggcgcagcta aaatcatctt taactgaaac aaaagagaag ttagaaatga
   115501 tccaacaaaa cgggaaaaag ttccaagaag cattagcaaa agaacagcct aaaatgtatc
   115561 aattaatgaa tcaagtccag cagctacgtg ctcgtaagaa aagccttcaa gaaatccaag
   115621 aaaactattt tggtttttac caaggggttc gattggtctt gcagcataaa cagcagcttt
   115681 cgggtattgt cggagcagtg gctgaactga tcgatgttcc tgcagatttc acgttagcta
   115741 tcgaagcagc tttaggtggg gcagcccagc atgtcatcgt tgaaaatgaa aaagatgctc
   115801 ggcaagccat cacgtatttg aaacagcaaa gaggaggaag agcaacattc cttccactga
   115861 cgacaatcaa accaagacaa ttaccggctc atatattgac acaagcagca gctgtagaag
   115921 ggtttatagg gattgccagt gaacaagtca gttatcccga tcaaatccaa actgtggttc
   115981 aaaacctgct aggaacgatc cttttagcca aagacttaac tagtgccaat gcaatcgcgc
   116041 aaacgatccg ctatcaatat cgagtggttt ccttagaagg tgatgtgatg aatgccggag
   116101 gatccatgac aggtggagcg aataaacgag gaaaccaagg cagtttgttt gtacaaaatc
   116161 aagaattgaa acagttgact agtgaatttg aagaagcaga taaacaactc caagcacaag
   116221 aaaaaaaagt tcaggagctg caacaagaaa cagctcgttt agccgaagaa caagaagttt
   116281 tgcgtacacg aggcgaacaa ttacgttttg aagaacaaga agcgacaaat cagctacaaa
   116341 acatcataaa tgaacttgaa cgttttgaaa aagaaaagca aatctcaact tttgagacac
   116401 gtgaactgca gcagtttatc gaagattacg aaaagcaaac gaacgaattg aaagacaaac
   116461 aaacagatct tgaatcgcaa cgacaaaaaa tcgacgaaga aatcaaatcg ttaagtcaag
   116521 aaagcgacca gatggaagcc agaagagcac aagtacaaag tcaaaaagca caagaacaag
   116581 cagatcttgc tgtcttgaaa gagcagttta atcatctgca gatccagctc cgcggtgccc
   116641 gagtccaaaa agcagaggca accgaacgtc aagaagcgat agaaaagcag ttggcgacat
   116701 tgacagcaga cttttctgat catgaagtca cagaagaaag tttggaaaaa caaattaacg
   116761 aattatctgc tcagcgagaa acattaaaag ccgagttggc aaaagccaaa gagcagcgag
   116821 atagaaggca aaaggagatc gataagcttg aagcagtctt ggcagagcgt aatcgtgagc
   116881 aaaaagcacg actgtcggaa caatccaaat tagaagtcca aaaagaccga gctgaaatga
   116941 ttttagataa tcatttgacc tatctgcagt cagaatatca gctgacattt gagaaagctt
   117001 cccaagacta tcaagaaaca accgatatcg aagacagtag aacaaaggtt tcatccttaa
   117061 aagaacagat tgaaaaactg ggaccagtaa acttaaattc aatcgaacaa tacgaacaag
   117121 tcagtgaaag acatacattc ttagcaacac agcgagatga tctgttagca gcgaaaaacc
   117181 aattgtttga aacgatggat gagatggatg atgaagtgcg gacaagattc aaagaagtat
   117241 ttgaagctat ccgtcaagaa ttcaaaattg tctttccaaa tatgtttggc ggcggtaaag
   117301 ctgaattagt actgacggaa ccaactgatt tgctgaaaac aggtattgag attgaagtac
   117361 aacctcctgg caaaaaactg caaagtctaa gtttgctttc tggaggagaa cgagcactta
   117421 cagccatcgc gttgctcttt tccattatcc gtgtctgtcc tgttccgttt tgtatcttag
   117481 atgaggtaga agcagcgtta gatgaagcca acgtgaaacg ttttggtcgt tacttgagcg
   117541 atttccaaga tgacacacaa tttatcgtag tcacacaccg caaaggaacg atggtcgcag
   117601 cagatgtact gtacggagtg acgatgcagg aatccggtgt atcaaaaatc gtttctgtac
   117661 ggatggaaga tatcaatgaa gaggcgaaaa tcaacgaaac gaaagtgtag gaacgaaaat
   117721 gatcaaatta gtagcaatcg atttggacgg tacattatta aatgaacaaa agctgatttc
   117781 agatgagaat aaacaagcat tagcacaagc aaaacagcaa ggggtcaaga tcgttctatg
   117841 tacaggacgc cccttagctg cgatggcgca ttatctgcaa gaattaggac tggtagatga
   117901 aggtgactac agcatcactt tcaacggcgg tttggtacaa aaaaatgata ctggtgaaat
   117961 catggaaaag aaagtgatgg aagtatcaga tatccaacgc ttatacaaac tggctcagca
   118021 attggatctg ccactagatg ttttgtctga caatgtggtt ttacagctgc ctagtgcccc
   118081 aaggaagcaa tccttgtaca atgtgttgaa taagctgctg caattccaac cagcggatat
   118141 aagcgatatt acagatgaat ttgtgcttaa taaggcagta atcgcttatg accaagaaga
   118201 attagatcct aaaatcaaag aaataccagc agaattccat gaaatgtatg agatcatcaa
   118261 aacaagaagt atgcttttgg aatttatgcc aaaaggtgtt acaaaagctt atggtatttc
   118321 tttattggca aaagatcttg gtttgaaaca agaagaaatc atggcgatcg gtgatgagga
   118381 aaatgattta ccgatgatcc aatatgctgg actaggcgta gcgatggaga atgctgtgcc
   118441 tttcgtcaaa gaagcagcag atttcgtgac agccagcaat gaagaaaatg gcgtagccaa
   118501 agtgatccaa aaatttgtat tagagtaggg ggagtcaaat gggatttttt gataaaatca
   118561 agcgtgcttt tactggcgaa gagaaaacag aagaagttga agtacaggag aagtacgaca
   118621 agggtttaga aaagacgcgt aaaacatttg gtgaacggat gaatgagttg tttgccaatt
   118681 ttcgaacagt cgatgaagac ttttttgaag aattagaaga aacacttatc ggtgcagatg
   118741 taggttttga aacagcgata cgaatcaccg aagcattacg tcaagaagtg aaactcagaa
   118801 atgcgaaaaa atcggcagaa gtccaaaatg cgatcatcga gaaacttgtg gatctctatg
   118861 aagcggaagg aatcaatgaa gtaaatgaac taaatatcca agaagacgga ctaacagtta
   118921 ttttgtttgt cggtgttaat ggtgtaggga aaacaacaag tattggtaaa cttgcccatc
   118981 agttcaaaaa cgaaggtaaa aaagtattga tggcagcagc agataccttc cgcgctggag
   119041 caatcgacca gttagttgtc tggggcgaac gcgctggtgt tgaagttgtt cgtggcaatg
   119101 caggaggcga tccagcagct gtcgtattcg atgctttgga aagagcaaag acagagcagg
   119161 cagatgtttt actagttgat actgcaggcc gactgcaaaa taaagtgaac ttgatgaacg
   119221 aattagaaaa aataaaacga gtaatccagc gggaattacc agaagcaccc caagaaacac
   119281 ttcttgtatt agatgcaacc actggtcaaa acgcgatggt tcaagcaaaa caattcaaag
   119341 aaacaacaga tgtgaccggt cttgttttga caaaattaga tggtacagca aagggcggta
   119401 tcgtacttgc tatccgtaat gaattgcatt taccagtgaa attggtcggt cttggtgaag
   119461 gaatcgatga cttggagccg tttgatccaa atgattttgt cgttggattg ttcaaaggat
   119521 tactaaaaga agaataaccc atgtctaaaa agcaggagct gtgacaaaag ttgcagctcc
   119581 ttgtttgaat gattgttttt aacatagctg tgtttttgat gccttcattt ttatacttat
   119641 ttgtaagcgg ttctcaaaca atttcgttct ttttcttaga ctttttgatt ataattagat
   119701 tcatatgaat tggaggtcac ttaatgatga attttaagca attattattg catgtcaatg
   119761 cgcgcccttt tatcgaccaa gctcgatttg gtatagaacg ggaaggacag cgggttgatc
   119821 ttgcaggaaa tctagcaaaa accgatcatc cagcaatctt tggcgatcga tcctatcacc
   119881 cctatatcca aacagatttt agcgaaacac aaacagagat gatcacccct gttaccgatt
   119941 ctattcccga attatttcag tatctcgctg ctgtttatga tgtgactgct cgttctatac
   120001 cgaaagaaga gatgatctgg ccattaagta tgccacctgc cttaccggaa aaagacgaag
   120061 agatcattat tgcaaaatta aaaaatttcg aagatgtctt gtatcgacgt tatttagcaa
   120121 aagaatacgg gaagcgaaaa cagatggtaa gcggtattca tttcaatttt gaatttggcg
   120181 atgagttgct aagaacattg ttcagccatc aggaagaatt tcaagatttt tccgaattca
   120241 aaacagaact ttatttgaaa acagcgagaa actttatgcg ctatcgctgg atgatcactt
   120301 atttattcgg tgcttcacca atgagtgaga agaactactt tttagatgaa tcacatccgc
   120361 aagaacctgt tcgcagtatt cgcaacagtg cgctgggcta tacgaatcat ccaaatgtga
   120421 aagtttccta tgcttctatg aaacagtatt tagcagatat cgagcgaatg atcgaagaag
   120481 ggaaactttc ggaggagaaa gaattttata caccgcttcg tttccgaggc ggaaagaaag
   120541 tcgcagattt agcaacaaca ggtgttcgtt atattgaatt gcggaatatc gatttgaatc
   120601 cttatgcaag attgggtatc aatccagagc aagttcggtt cttacaatta ttcctgatgt
   120661 acatgttatg gacagaagaa aaagaagact gtgaccaatg ggtagcagaa ggtacgactc
   120721 gaaataacaa agtagcacta gaacaaccat cagatcaaac agaatttcat caagaaggta
   120781 gagaaattct tgaaggaatg aagcaaatgc tggttgaatt ggattggttg gattctcttt
   120841 atttagtaga ggaagcattg actcaaatgg atcatcctga acaaacgtta gcagcgaaac
   120901 tctatcaaga agcacagcta tcgagtcagc aagaagttgc tgtggcattg ggacatcaat
   120961 attataaaga aagccatgaa cgtccctatc agttggccgg ttttcgcgaa atggaacttt
   121021 ctactcagat atttatgttc gatgccatcc aaaaaggtgt ccaagtcaaa gtattagatg
   121081 agtcggatca atttttgcgt ctgcaattcc aagaccatgt agaatatgtg aaaaatgcaa
   121141 acatgacaag taaggacagc tatatcgtcc cacttatcat ggaaaacaaa acagtaacga
   121201 aaaaagtctt aaaagaagct gggttccggg taccaggagg cgcagaattt tcatccatgg
   121261 aagaagcggt aaaagcttat ccgagatttg ccgagcaggc atttgtgatc aaacctaaat
   121321 caaccaatta cgggttaggt atcacgattt tcaaggaagg agctagtctg gaagattatc
   121381 aagcaggttt agccattgct tttcgtgaag acagttcggt tttagtagaa gaatttatgc
   121441 cgggaacgga atatcgtttc tttgtgatcg acggagaagt ccaagccatc atgttgcgag
   121501 tccctgctaa tgttattggt gacagtatcc gaacagtgaa agaacttgtt gaagaaaaaa
   121561 atagtgaccc tttgcgtgga acgaatcatc gtgcaccttt agaattgatc caattaggtg
   121621 aattagaaca attgatgttg aaagaacaag ggttgacgat cgaatcagtt ccccaagcca
   121681 atcaaattgt ttatctaagg gagaactcaa atatcagtac aggtggtgat tcgatcgata
   121741 tgactgatga attttctgaa gcttacaaaa aaatcgccgt ttctgcggta gaagcactag
   121801 gagctaagat tagtggtatc gatttgatta taccagataa agaaatcgat cctacaactg
   121861 ataaaaaagc atatgggatc atcgaagcaa atttcaatcc agccatgcat atgcatgttt
   121921 atccttttgc aggaaaaggc agaagattga cgatgaatgt attgaaattg ttatatcctg
   121981 aagtatttta aaagaaaaag cttttgacag attgtcctat ttgatgtcaa tctgatcaaa
   122041 agcttttttt gcatgtaaaa atttatgtgt tttttcgttt taaaataaac gatcccagaa
   122101 gctttttttc ttttttggtt tttctttttc agctggcgaa gagttttctt ctgggtattt
   122161 tttttcgata tcaatcacag gttcatttac tgcttctttt gctgttaaga gcaatccgaa
   122221 ttcctcagga tttgcagtga cgtaatcgtt gactacagtg aaacggctat tgtttttcgt
   122281 tgctagctgg atatattggt tttggacaga aaggggtaga gccccattca agagtatgga
   122341 agcatctgga tgttttttga gttcttttaa aaagttttct ttgttttttg gttggatcat
   122401 ttcagcaaca gtcatactaa gatagcagcg ttccctgaat gtccctaaat atttatgctg
   122461 ttcttcaggg ttcactaaag gtgtaccata aagtccctta tccaaatggc tttttacatc
   122521 atcttgtgcc ataaaaaata ccctccttct tctctttgtc tttcttacga ttatagcata
   122581 ttcccaataa tacctaaaac atatgaaaaa gcggttgctt ttgttcaacg attcacttaa
   122641 aataagaatg aaaatcattc tcaattagaa aggtggattg gatgcgctac ggacgactag
   122701 tagcattatt agttatttta agtagtattt cattgttcat cggagtatcg aatgtacaat
   122761 tgtcagaact gctccagtta gatgggcaaa gcttacaaat cttgctagtg actcgtttgc
   122821 cacgaacgat ttgtttgatc cttgtgggag cgaccagtag tatttgtggg ttgatcatgc
   122881 aacatttgac ccaaaataaa tttgtttcac caacgactgc gggcacgatg gatagtgcgc
   122941 gtttaggtat tttagtggct atgattttcc tacctggtgc atccttgatt gtccgatcct
   123001 tgacagcatt ttgctttgct tttgcaggaa cattgctttt tttatccctt acgcgattgt
   123061 tcctccagaa aaatcaattg atgcttccgt tgattggagt catgttaggg aatatcattg
   123121 gttcagttgc tacttttttt gcttatcaat tccagttggt acaaaatatg acttcatggc
   123181 ttcaagggaa ttttgcgact gtgatacgag gaaattatga gttattgtat gctgttgttc
   123241 cattgttgct cttggtttgg ctatttgctt accgatttac gatcattggt ctgggcgaat
   123301 cgtttgcagt aaatctggga atagattacc agaagatgca gtttttaggc attggcttag
   123361 tatcattggc tagtgcagtc atgttgatca tggtaggaag cattcctttt atcggagtga
   123421 tcattccgaa tcttgtctct agaatatatg gagatcaagt gcacaaaaca attggcgtaa
   123481 ctgctttagc aggtagtttg ttcttagtat tttgcgatct tgtcgctcgc gtgttgattt
   123541 ttccttatga aataccagtc agtgtgatcg ttggaatcat cggtggggct atcttccttt
   123601 atcttctgat aaggggacga cgatatgctt aaaaaaaagc catctatttt tattggtatg
   123661 cttgttcttg ttttatttgt tacaggaatg tacttgacga tccatacata tggaaactgg
   123721 cattttgcat gtgcattgag gagtaagaaa atttttgcat ttatccttgt ctcgctagct
   123781 gtcagcagtg ccacaatcag ctttcagaca attacgcata accagttttt gactccttca
   123841 gtattgggac ttgagtcgtt atatgtcctt gtccaaacgg tccttttctt ctttatcgga
   123901 ggagtgacga tgcttcagca gacaggtaca gtttttttct tattgaacgt tgggctgatg
   123961 gtcgggctga gtctattgtt atttttcttt cttttgaaaa aaatgagagc gaatcttttt
   124021 ttattactga tgtcagggat gattttaggt acgctttttg gtagtgtcag taccttttta
   124081 caagtcatca tggatccgaa tgaatatgat ttgcttcaag gcagattatt tgcaagcttt
   124141 ggcaatatcc agagtcagta tcttttgcct gcttctttga tcattatcgg ctgctggtac
   124201 ctgttatttc gatatcgaca tgtgctagac gttttccatc tcggaaatga acaagcagta
   124261 aacctcggga tagacacaga tcgttttgaa tttttgattt tatgttgtgt cagtcttttg
   124321 acagggacat caacggctct tgtgggtcca gttacttttt tagggtttat tgtcgcaaat
   124381 atcagttatc gtgtcttttc tacttatcgt catggtcagc tatttatcgg aagctttctg
   124441 gtagctatgc tgtttctgac aggaggacag ctcgcagtag agcagatttt cggctggaat
   124501 acaacagtga gtgtcgtcgt tgaatttgtc ggaggaattt attttgtcac aaaattgatt
   124561 cgcgaaagga agagtatcct atgattgatt tacaaaaggt caataaactg taccatggaa
   124621 aatcagtggt taaagatgta cagttaacga ttcctgaaaa gaagttgact gcttttatcg
   124681 gtccaaatgg tgctggaaag tcaacggtgt tgtcgatgat cagtcgtttg ataccaaaag
   124741 atacaggtga aatctattta gaccataacg aagtaaaggc ttggaaatcc aatgaattag
   124801 ccaaaaaatt atcgatccta cgacaatcga atgaaataaa tgtccaaatc accgtgaaag
   124861 aattagtaga atttggacga tttccttata cgaaaggaaa attgacgaca aaagacgagg
   124921 aaatcgttca ggaatcactg gaacacattg ggttagaaga aatagcggat caatcgattg
   124981 acactctttc aggcggtcaa ctccaacgtg cgtatattgc aatggtgcta gcgcaagaca
   125041 cggattatat tttactggat gaacctttga acaatctaga tatgaatttt gcggttcaaa
   125101 tcatgcagat tttaaaaaat ttagtacaag aaatcgggaa aacaattgtt attgttcttc
   125161 atgatatcaa ctttgctgca agttatgcag acgaaattgt tgcaatgaaa gatggacagt
   125221 tatttacgca aggaacgacc caagaaatga taaaaaaaga tgtattggat gaattatacg
   125281 aaatggacat acggatttgt gagattgaag gccgcagatt ctgtctttat ttctaaaact
   125341 aacattagga gagaagagat gaaaaaatta gtagtaggta tcttgattct agcatcattt
   125401 ggtttagcag catgtggaaa tagcaacaac accagtcagg cagacacaaa aaaaagcagc
   125461 acacaaactg aaactacatt gacgataaca gatagtaatg gagaccaaat cgaggtgcca
   125521 aataatccag aaaaagtcgt cgtattcgac aatggttctt tagatacgat ggatgctctt
   125581 ggtgttggag ataaggtagt tggagcagct acaagcagcc ttcctgagta tctttcatcc
   125641 tataaaaaag tagaatcagc aggtggaata aaagaaccag acttagaaaa aattaatcag
   125701 cttcagccag atctaatcat catttctggc cgacaaagag attttcaaaa agatctaagt
   125761 caaattgctc cgaccatttt cctttcttta gatgcgaaaa atccatggga atctttccag
   125821 caaaatgtca ctgctttagg ggagatcttt ggtaagcaag aagaagctaa aactcaatta
   125881 gaggaattat ctagtgcaat cgatcagacg aaaaagaaag cagaagctac tgacaaaaaa
   125941 gcactagtca cacttgtgaa tgaagggcaa ttatcagcct acggatctgg ttctagattc
   126001 ggtttcatcc atgatttatt tggctttgaa caagcagatg atcaaatcga agcatccact
   126061 cacggtcaaa gtgtttctta tgaatatgtg ctggaaaaaa atccggatat cttatttgta
   126121 gtagacagaa caaaagctat tggtggagac gacagcaaag atgatatttc tgccaatgaa
   126181 ctggtagcac aaacgaatgc tggtaaaaat cagcagatca tctcccttga accagatgtc
   126241 tggtatttaa gcgggggcgg tttagaatca atgaaactga tgatcgaaga tgtgaatcaa
   126301 gcatttaaat agcataaata acagaggatt aaactctcat actatgtaac aataatgttt
   126361 cttacattct taaatagcaa gagcctatcc tcaaagaagt tatcaaaaac catccgtaaa
   126421 atcgtattga tgattttacg gatggttttt atttatttga gaaatctttt ttcaacgtga
   126481 attcattatc tacatcatac gggttgattc tagaatgggg agtggcaaaa aatagtgtga
   126541 tccatttttt cagcatcaag atcgcctcct ttgatttgaa tcaaaggtac aaagcgaaac
   126601 ttagataaaa cttaaattta gatattttta ttttgtaccg atctcttctt taaacgatgt
   126661 tccatctgct gcttctcggc aataagtcca ctagactaga aaatatgaga agctattttc
   126721 tgtccagcgt tcttattact caaaacaaat cgcagttgtc acaatctctt ctaaacgatg
   126781 ttccatctgc tgcttctcgg caataagccc actagactag aaaatatgag aagctatttt
   126841 ctgtccagcg ttcttattac tcaaagcaaa tcgcagttgt cacaatctct tctaaacaat
   126901 gttcaatcag ctgaccttcg gtattagctc aaagcactga tttcacaacc tctatttagg
   126961 catgtgtctc agcaagcggt tgatagttga tgatctgcat ttttcgataa aaatcggcgg
   127021 gaagcttact ccaccgtttt agtaattgat agaaataact ctcttctgct ttgattttat
   127081 actcgcttaa tatcaatcca aaactattcg ttttttttga agctaatttt ttataaatat
   127141 ccaatgcttt ggttttatct tcattgacaa agagtgtttt tacttcaata taagaaccct
   127201 cgatattttg tgtttcttcg ataaaataga tgttttttat atattccttc atagtgattc
   127261 ctccaaagaa gtcttttatt tgataagttt actctaccga agagttgtta ataatccgtg
   127321 aacaaaaagt aattcttttt ccaatagttg ttaaaggttt tttatttttt atagtatttt
   127381 ttgttattta agaaaggaat aaggttaaac aaataacagg ttgctttttg ggtctttttc
   127441 cgttcaagaa actgaacgaa gaaaagggaa agttgtctct tttgtgataa gagaaatcat
   127501 aataaacgaa tgacttactt tccaataaat tgagaacagt cagaaccaga caaattagtt
   127561 gcatctgatg aataaagtga ttattctatg acatgaggtg atacagatga aattagaagt
   127621 gacaaaagaa gcacaagaag tattgaagaa taaattagaa gcagacgatc aacttttatt
   127681 agatatcgaa aacggtgacg gtccatttgc agaaagccaa gtcagttgcc aattggatac
   127741 ggcatttcga ttgatcattg tcaaaaaaga tacacaaaca gatctaagtc tttattctgt
   127801 agtggctgat acaccagttg gaccaatcaa aatcaaagac agtgcaatac tttacatgga
   127861 tgatccatcc acacttgctt tagaaccaac ttataatagt ttacaattaa aaggaccaag
   127921 cggcttgaga aaaggcaact tgcaagttgt tcgaaaagac tagagggata aaatgggaaa
   127981 attggcgatc atcagcgacc tacatgtgga catcaataaa ttcggcgaat cagagctgat
   128041 gcagctttgg caagttttgc aaaagcacaa gatcactcgg cttcatctag ccggagatac
   128101 ggctaataaa gtagaccgtt gcctagctgt tgtcgaattt ttcgtcaata aaggattatc
   128161 tacgacattt catttcggca atcacgagtt ggcagatgtg cccaatgaac agatgatgga
   128221 ccattttcca gacccacatt ttttaaatga acggtatatt gctttaaatg agcagaccgt
   128281 tcttttaggg atgaatggct ggtacgacta tcagttttcc gaattgaaag attacgaggc
   128341 aatcgtacga atgaagcgtt tgtattggta tgatcggttc atccagcgtg ggaaaacaga
   128401 tctcgaggtc aatgcagaaa tgcttgcagc tgcaaaaaat ttgctagacc agctggaagc
   128461 aaaaaaactt gaggtgattt tatccactca tttcgttcct aaacgggcat ttatcatgta
   128521 tcaatctgct ccttatgagc gttggaacaa attaaatgca tttttaggat cagaatcatt
   128581 cggagaatta cttgaccgtt attcaaatat caaacaagta gtttttggcc atacgcatcg
   128641 tcgctttgaa gataaatcca tcggtcacac gatttacagc tgcagacctt ttggttatta
   128701 ttatgaatgg cagctgaccc gagattttgt cttgaaagaa cagttgctag acagctatga
   128761 tcctatgaaa ttacgtgtcc tcttgcgtgc ccatcaccca gcttttcagg cctatcaaac
   128821 acaacatttg caagaggaat ttgaacaagc gatgacaatc gttccgtatt gagacagcat
   128881 tagtaatgtg taaaagaaaa taccttgtaa aacataagga taagtaagag cagtagatcc
   128941 atttatcgtg gatatgctgc tttttttgcg gaaaataatc agcgaatgtt tatttgatcg
   129001 gatgatttgt aactcgcaga gtactagatg caagcgtgta ttcttttttt gaacgataat
   129061 cacaaaaaaa atataatata cattttttat ttaattataa t
//
LOCUS       DAXLPQ010000003       105210 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.003, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000003 DAXLPQ010000000
VERSION     DAXLPQ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 105210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.003"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            55..828
                     /locus_tag="ACF3UO_000257"
     CDS             55..828
                     /locus_tag="ACF3UO_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656318.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(909..1478)
                     /gene="thiT"
                     /locus_tag="ACF3UO_000258"
     CDS             complement(909..1478)
                     /gene="thiT"
                     /locus_tag="ACF3UO_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFD3656319.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(1544..1646)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(1652..2623)
                     /locus_tag="ACF3UO_000259"
     CDS             complement(1652..2623)
                     /locus_tag="ACF3UO_000259"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD3656320.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(2717..4090)
                     /gene="glmU"
                     /locus_tag="ACF3UO_000260"
     CDS             complement(2717..4090)
                     /gene="glmU"
                     /locus_tag="ACF3UO_000260"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFD3656321.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(4593..5411)
                     /gene="purR"
                     /locus_tag="ACF3UO_000261"
     CDS             complement(4593..5411)
                     /gene="purR"
                     /locus_tag="ACF3UO_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFD3656322.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(5578..6402)
                     /locus_tag="ACF3UO_000262"
     CDS             complement(5578..6402)
                     /locus_tag="ACF3UO_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFD3656323.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(6375..7055)
                     /locus_tag="ACF3UO_000263"
     CDS             complement(6375..7055)
                     /locus_tag="ACF3UO_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3656324.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(7078..8016)
                     /locus_tag="ACF3UO_000264"
     CDS             complement(7078..8016)
                     /locus_tag="ACF3UO_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFD3656325.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(8261..9112)
                     /gene="ispE"
                     /locus_tag="ACF3UO_000265"
     CDS             complement(8261..9112)
                     /gene="ispE"
                     /locus_tag="ACF3UO_000265"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFD3656326.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(9266..11839)
                     /gene="mprF"
                     /locus_tag="ACF3UO_000266"
     CDS             complement(9266..11839)
                     /gene="mprF"
                     /locus_tag="ACF3UO_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFD3656327.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            11980..12786
                     /gene="proC"
                     /locus_tag="ACF3UO_000267"
     CDS             11980..12786
                     /gene="proC"
                     /locus_tag="ACF3UO_000267"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFD3656328.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(12865..14421)
                     /gene="rny"
                     /locus_tag="ACF3UO_000268"
     CDS             complement(12865..14421)
                     /gene="rny"
                     /locus_tag="ACF3UO_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFD3656329.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(14832..15881)
                     /gene="recA"
                     /locus_tag="ACF3UO_000269"
     CDS             complement(14832..15881)
                     /gene="recA"
                     /locus_tag="ACF3UO_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFD3656330.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(15990..17231)
                     /locus_tag="ACF3UO_000270"
     CDS             complement(15990..17231)
                     /locus_tag="ACF3UO_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFD3656331.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(17471..18049)
                     /gene="pgsA"
                     /locus_tag="ACF3UO_000271"
     CDS             complement(17471..18049)
                     /gene="pgsA"
                     /locus_tag="ACF3UO_000271"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFD3656332.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(18258..19181)
                     /locus_tag="ACF3UO_000272"
     CDS             complement(18258..19181)
                     /locus_tag="ACF3UO_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFD3656333.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(19920..21206)
                     /locus_tag="ACF3UO_000273"
     CDS             complement(19920..21206)
                     /locus_tag="ACF3UO_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD3656334.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(21199..22467)
                     /locus_tag="ACF3UO_000274"
     CDS             complement(21199..22467)
                     /locus_tag="ACF3UO_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD3656335.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            22719..23180
                     /gene="mscL"
                     /locus_tag="ACF3UO_000275"
     CDS             22719..23180
                     /gene="mscL"
                     /locus_tag="ACF3UO_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFD3656336.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(23239..23685)
                     /locus_tag="ACF3UO_000276"
     CDS             complement(23239..23685)
                     /locus_tag="ACF3UO_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3656337.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(23778..24023)
                     /locus_tag="ACF3UO_000277"
     CDS             complement(23778..24023)
                     /locus_tag="ACF3UO_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFD3656338.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(24138..24716)
                     /locus_tag="ACF3UO_000278"
     CDS             complement(24138..24716)
                     /locus_tag="ACF3UO_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFD3656339.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(24793..25323)
                     /locus_tag="ACF3UO_000279"
     CDS             complement(24793..25323)
                     /locus_tag="ACF3UO_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFD3656340.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(25327..26187)
                     /gene="rlmB"
                     /locus_tag="ACF3UO_000280"
     CDS             complement(25327..26187)
                     /gene="rlmB"
                     /locus_tag="ACF3UO_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFD3656341.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(26180..26575)
                     /locus_tag="ACF3UO_000281"
     CDS             complement(26180..26575)
                     /locus_tag="ACF3UO_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFD3656342.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(26572..27984)
                     /gene="cysS"
                     /locus_tag="ACF3UO_000282"
     CDS             complement(26572..27984)
                     /gene="cysS"
                     /locus_tag="ACF3UO_000282"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFD3656343.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(27981..28517)
                     /gene="epsC"
                     /locus_tag="ACF3UO_000283"
     CDS             complement(27981..28517)
                     /gene="epsC"
                     /locus_tag="ACF3UO_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFD3656344.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(28603..28842)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(28839..30299)
                     /gene="gltX"
                     /locus_tag="ACF3UO_000284"
     CDS             complement(28839..30299)
                     /gene="gltX"
                     /locus_tag="ACF3UO_000284"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFD3656345.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(30469..31626)
                     /locus_tag="ACF3UO_000285"
     CDS             complement(30469..31626)
                     /locus_tag="ACF3UO_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFD3656346.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(31660..33030)
                     /gene="radA"
                     /locus_tag="ACF3UO_000286"
     CDS             complement(31660..33030)
                     /gene="radA"
                     /locus_tag="ACF3UO_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFD3656347.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(33093..33620)
                     /locus_tag="ACF3UO_000287"
     CDS             complement(33093..33620)
                     /locus_tag="ACF3UO_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFD3656348.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            33850..34656
                     /gene="proB"
                     /locus_tag="ACF3UO_000288"
     CDS             33850..34656
                     /gene="proB"
                     /locus_tag="ACF3UO_000288"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFD3656349.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            34653..35900
                     /locus_tag="ACF3UO_000289"
     CDS             34653..35900
                     /locus_tag="ACF3UO_000289"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFD3656350.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            35976..36320
                     /locus_tag="ACF3UO_000290"
     CDS             35976..36320
                     /locus_tag="ACF3UO_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656351.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(36437..36763)
                     /locus_tag="ACF3UO_000291"
     CDS             complement(36437..36763)
                     /locus_tag="ACF3UO_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656352.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(37378..38580)
                     /locus_tag="ACF3UO_000292"
     CDS             complement(37378..38580)
                     /locus_tag="ACF3UO_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3656353.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            38697..39212
                     /locus_tag="ACF3UO_000293"
     CDS             38697..39212
                     /locus_tag="ACF3UO_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3656354.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(39411..39857)
                     /locus_tag="ACF3UO_000294"
     CDS             complement(39411..39857)
                     /locus_tag="ACF3UO_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFD3656355.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(39904..41382)
                     /gene="msr(C)"
                     /locus_tag="ACF3UO_000295"
     CDS             complement(39904..41382)
                     /gene="msr(C)"
                     /locus_tag="ACF3UO_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFD3656356.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(41736..42365)
                     /locus_tag="ACF3UO_000296"
     CDS             complement(41736..42365)
                     /locus_tag="ACF3UO_000296"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3656357.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(42349..42813)
                     /locus_tag="ACF3UO_000297"
     CDS             complement(42349..42813)
                     /locus_tag="ACF3UO_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3656358.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(43300..44568)
                     /locus_tag="ACF3UO_000298"
     CDS             complement(43300..44568)
                     /locus_tag="ACF3UO_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3656359.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(44799..45536)
                     /locus_tag="ACF3UO_000299"
     CDS             complement(44799..45536)
                     /locus_tag="ACF3UO_000299"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3656360.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(45603..46172)
                     /locus_tag="ACF3UO_000300"
     CDS             complement(45603..46172)
                     /locus_tag="ACF3UO_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFD3656361.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            46300..47172
                     /locus_tag="ACF3UO_000301"
     CDS             46300..47172
                     /locus_tag="ACF3UO_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3656362.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            47514..48386
                     /locus_tag="ACF3UO_000302"
     CDS             47514..48386
                     /locus_tag="ACF3UO_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFD3656363.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            48383..50341
                     /gene="nagE"
                     /locus_tag="ACF3UO_000303"
     CDS             48383..50341
                     /gene="nagE"
                     /locus_tag="ACF3UO_000303"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFD3656364.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(50673..51524)
                     /locus_tag="ACF3UO_000304"
     CDS             complement(50673..51524)
                     /locus_tag="ACF3UO_000304"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3656365.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            51647..52114
                     /locus_tag="ACF3UO_000305"
     CDS             51647..52114
                     /locus_tag="ACF3UO_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFD3656366.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(52377..52859)
                     /locus_tag="ACF3UO_000306"
     CDS             complement(52377..52859)
                     /locus_tag="ACF3UO_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3656367.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(52959..53822)
                     /locus_tag="ACF3UO_000307"
     CDS             complement(52959..53822)
                     /locus_tag="ACF3UO_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3656368.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            54420..55295
                     /locus_tag="ACF3UO_000308"
     CDS             54420..55295
                     /locus_tag="ACF3UO_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFD3656369.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(55440..55592)
                     /locus_tag="ACF3UO_000309"
                     /pseudo
     CDS             complement(55440..55592)
                     /locus_tag="ACF3UO_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(55860..57191)
                     /locus_tag="ACF3UO_000310"
     CDS             complement(55860..57191)
                     /locus_tag="ACF3UO_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3656370.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(57340..58053)
                     /locus_tag="ACF3UO_000311"
     CDS             complement(57340..58053)
                     /locus_tag="ACF3UO_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3656371.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            58228..59652
                     /locus_tag="ACF3UO_000312"
     CDS             58228..59652
                     /locus_tag="ACF3UO_000312"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3656372.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            59951..60658
                     /locus_tag="ACF3UO_000313"
     CDS             59951..60658
                     /locus_tag="ACF3UO_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFD3656373.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            60645..60968
                     /locus_tag="ACF3UO_000314"
     CDS             60645..60968
                     /locus_tag="ACF3UO_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFD3656374.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(61057..62094)
                     /locus_tag="ACF3UO_000315"
     CDS             complement(61057..62094)
                     /locus_tag="ACF3UO_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3656375.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(62415..63398)
                     /locus_tag="ACF3UO_000316"
     CDS             complement(62415..63398)
                     /locus_tag="ACF3UO_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFD3656376.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(63813..64583)
                     /locus_tag="ACF3UO_000317"
     CDS             complement(63813..64583)
                     /locus_tag="ACF3UO_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3656377.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(64576..65511)
                     /locus_tag="ACF3UO_000318"
     CDS             complement(64576..65511)
                     /locus_tag="ACF3UO_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656378.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65827..67476)
                     /locus_tag="ACF3UO_000319"
     CDS             complement(65827..67476)
                     /locus_tag="ACF3UO_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFD3656379.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(67593..70196)
                     /locus_tag="ACF3UO_000320"
     CDS             complement(67593..70196)
                     /locus_tag="ACF3UO_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFD3656380.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(70208..71257)
                     /locus_tag="ACF3UO_000321"
     CDS             complement(70208..71257)
                     /locus_tag="ACF3UO_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3656381.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(71283..71597)
                     /locus_tag="ACF3UO_000322"
     CDS             complement(71283..71597)
                     /locus_tag="ACF3UO_000322"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFD3656382.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(71613..72059)
                     /locus_tag="ACF3UO_000323"
     CDS             complement(71613..72059)
                     /locus_tag="ACF3UO_000323"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFD3656383.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(72060..73982)
                     /locus_tag="ACF3UO_000324"
     CDS             complement(72060..73982)
                     /locus_tag="ACF3UO_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3656384.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(74194..75090)
                     /locus_tag="ACF3UO_000325"
     CDS             complement(74194..75090)
                     /locus_tag="ACF3UO_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3656385.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(75083..75763)
                     /locus_tag="ACF3UO_000326"
     CDS             complement(75083..75763)
                     /locus_tag="ACF3UO_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3656386.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(75764..76546)
                     /locus_tag="ACF3UO_000327"
     CDS             complement(75764..76546)
                     /locus_tag="ACF3UO_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3656387.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(76539..77456)
                     /locus_tag="ACF3UO_000328"
     CDS             complement(76539..77456)
                     /locus_tag="ACF3UO_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3656388.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(77620..77874)
                     /locus_tag="ACF3UO_000329"
     CDS             complement(77620..77874)
                     /locus_tag="ACF3UO_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656389.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            78731..81958
                     /gene="fss3"
                     /locus_tag="ACF3UO_000330"
     CDS             78731..81958
                     /gene="fss3"
                     /locus_tag="ACF3UO_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFD3656390.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            82071..82385
                     /locus_tag="ACF3UO_000331"
     CDS             82071..82385
                     /locus_tag="ACF3UO_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFD3656391.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            82398..82772
                     /locus_tag="ACF3UO_000332"
     CDS             82398..82772
                     /locus_tag="ACF3UO_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFD3656392.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            82782..83117
                     /locus_tag="ACF3UO_000333"
     CDS             82782..83117
                     /locus_tag="ACF3UO_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFD3656393.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            83200..84540
                     /locus_tag="ACF3UO_000334"
     CDS             83200..84540
                     /locus_tag="ACF3UO_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFD3656394.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            84618..85292
                     /locus_tag="ACF3UO_000335"
     CDS             84618..85292
                     /locus_tag="ACF3UO_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFD3656395.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            85285..85449
                     /locus_tag="ACF3UO_000336"
     CDS             85285..85449
                     /locus_tag="ACF3UO_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656396.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            85525..86667
                     /gene="dcm"
                     /locus_tag="ACF3UO_000337"
                     /pseudo
     CDS             85525..86667
                     /gene="dcm"
                     /locus_tag="ACF3UO_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            86657..86947
                     /locus_tag="ACF3UO_000338"
     CDS             86657..86947
                     /locus_tag="ACF3UO_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656397.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            87206..88390
                     /gene="mobT"
                     /locus_tag="ACF3UO_000339"
     CDS             87206..88390
                     /gene="mobT"
                     /locus_tag="ACF3UO_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFD3656398.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            88387..88524
                     /locus_tag="ACF3UO_000340"
     CDS             88387..88524
                     /locus_tag="ACF3UO_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFD3656399.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            89270..91180
                     /gene="ltrA"
                     /locus_tag="ACF3UO_000341"
     CDS             89270..91180
                     /gene="ltrA"
                     /locus_tag="ACF3UO_000341"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3656400.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            91284..91508
                     /locus_tag="ACF3UO_000342"
     CDS             91284..91508
                     /locus_tag="ACF3UO_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656401.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            91521..92024
                     /locus_tag="ACF3UO_000343"
     CDS             91521..92024
                     /locus_tag="ACF3UO_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFD3656402.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            92084..92473
                     /locus_tag="ACF3UO_000344"
     CDS             92084..92473
                     /locus_tag="ACF3UO_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3656403.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            92460..94907
                     /locus_tag="ACF3UO_000345"
     CDS             92460..94907
                     /locus_tag="ACF3UO_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3656404.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            94912..97035
                     /locus_tag="ACF3UO_000346"
     CDS             94912..97035
                     /locus_tag="ACF3UO_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFD3656405.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            97032..98036
                     /locus_tag="ACF3UO_000347"
     CDS             97032..98036
                     /locus_tag="ACF3UO_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFD3656406.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            98055..98966
                     /locus_tag="ACF3UO_000348"
     CDS             98055..98966
                     /locus_tag="ACF3UO_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3656407.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            99153..99409
                     /locus_tag="ACF3UO_000349"
                     /pseudo
     CDS             99153..99409
                     /locus_tag="ACF3UO_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(99626..99841)
                     /locus_tag="ACF3UO_000350"
     CDS             complement(99626..99841)
                     /locus_tag="ACF3UO_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656408.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(100090..100308)
                     /locus_tag="ACF3UO_000351"
                     /pseudo
     CDS             complement(100090..100308)
                     /locus_tag="ACF3UO_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(100603..102042)
                     /locus_tag="ACF3UO_000352"
     CDS             complement(100603..102042)
                     /locus_tag="ACF3UO_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3656409.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            complement(102630..103262)
                     /locus_tag="ACF3UO_000353"
     CDS             complement(102630..103262)
                     /locus_tag="ACF3UO_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFD3656410.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            complement(103611..105062)
                     /locus_tag="ACF3UO_000354"
     CDS             complement(103611..105062)
                     /locus_tag="ACF3UO_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3656411.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
BASE COUNT        31601 a        21164 c        19210 g        33235 t
ORIGIN      
        1 aatgcaaatg ttgtaaaata aaagagatta agaggaaata agaggaggaa catgatgact
       61 gagtcagttt atgtacatat tgataccaca agtaatgctg ttttaacaaa agggctgact
      121 gctactgact ttgcaaacag tatcgtgcat tttcctcaaa acttgctctt gcttgatcca
      181 tctgcttctg ctggagaata tgaatcccat acagggctga aagtaatccg tggtacagaa
      241 aatattcagc gtttcttttc ctcttctcgt aacaggcgtg gattcgatga attgaagtgg
      301 atcgacttta ctgatttaac gatgctgaaa gaattgacac ctttagaaat ttcagaatta
      361 ttatattttg gtcatatgaa aacacatctt cattcgccgt ttttttataa actacagaat
      421 aattttgtat acttcgatct taatgatcag ctgaatcgga tttattatcg ctatttagat
      481 gaattttata ggatttttgc tagtaaatta agttcgatct tgtcagataa gatcaatgta
      541 aaaaaatctt ttttcaaaaa agaaacacct gttgaaaaaa tcagtgtgga attattgaaa
      601 gaaatgcgta atttgatgca ggaagggatc attttttctt ttgatcaagt tggtttgatc
      661 gatggtaaat atcgtatccc aatctatgtg attgaagatt atatttggaa attaaaaggc
      721 acccggtatc gagaagagga aatcatcgct actttaatct actctgtcac cgatcgacac
      781 tggcaattgg tagaagatgc cgatctttct tatctgccat tgaagtagat ctatttctta
      841 tcaaaaaata aaaaggaaac aagaaactag gacatgattc tgtctcaagt ttcttgcttc
      901 ttttttattt acagctcctg tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg
      961 atccctaata aaacgatgat cgttacaata gctgtactca acccgctggc accattcatt
     1021 acgaaagaaa agagccaagg attcatcccc catagtgcat acgctcccca gaaaaccact
     1081 cctgcaataa aatgccaaaa atatctggaa agtgcgccaa tcaatgcacc aaacacgatg
     1141 ctttttctaa tttgtttcgt attatcgtct acatagcctt tttggacatt tgaagccatg
     1201 agccctgctg cgcctgcaaa agtataggca atcgggtact caatcaacac ttgaacgaca
     1261 cttaaataat aaacttgtcc caacggaaaa tgtaggatgc cccaaatgaa acctgccagc
     1321 atccctgcct ttgtccctct tcttaacgca aaaagagtca atggaatctg ccctaatgaa
     1381 atagaaaaac tgctgccgat ctggatcgga atcaacgaca acaccatcgc taacgctgca
     1441 acaatcgttc cttctaccca aactctattt tttcccataa aaaaacttcc tcctttgaat
     1501 aaaaaagtca caaaggagga agcagctttc gaaaatagtc aaacagctgt ttattcacaa
     1561 ttcctacgct cgcataaccg atacaggtac gaagggttta gaaatagatt caatctcagc
     1621 ccaattggac tcccctttgt gagtttattt attatttatt ttttgtttca aacaatggac
     1681 taactggttt gttttcatgg atacgtttga ttgcatctcc cattagtccg ccaacactta
     1741 cttcatcgat tttgtcgatt ttacgatctt ctggaagata gatcgagtct gtaacaacta
     1801 gacgctcgat agctgaatct tctattcttt gtaaagcagg gccggataat actggatgtg
     1861 tacatgaagc atacacacta gttgcaccag cttctttcaa agcattggca gccaatgtga
     1921 tcgtacctgc tgtatcgatc atatcatcga tcagtacaca agttttgcct ttgacttgtc
     1981 caatgatatt cattacttct gcaacatttg cttttggacg gcgtttgtct atgatcgcaa
     2041 tcggagattt caaaaattcc gctaatttac gtgcccgtgt gacaccacca tggtctggtg
     2101 aaacaacgac aacatcatcg cctttgattc ctttttctaa gaaataattg gcaataagtg
     2161 gcgcacccat caaatgatcg actggaatat caaagaaacc ttggatttgg actgcatgaa
     2221 ggtccaaagt cagcattctt gttgcaccag ctttttgaat catgtttgct actaatttcg
     2281 ctgtgattgg ttcccgtgca cgtgctttac ggtcttgacg cgcatagcca taataaggca
     2341 tgactacgtt gattgttttt gcacttgctc gtttcagtgc gtcaatcatg atcagcaact
     2401 ccatcaagtt atcattgact gggctgctcg ttgattgaat aacatagaca tgcgatccac
     2461 gaatactttc ttcaatgttt acttgaattt ctccatcact aaattgagta acagatgatt
     2521 ttcctaactc gacgccgact gctgctgcaa ttttctctgc taatgggcga ttggaattta
     2581 acgcaaaaat ttttaatctt gggtcaaagt aatgttttga catggggacc tccactttct
     2641 ttttcacaac tctagaattc tacctaataa atagtagtca tattttttaa ataaatcaag
     2701 tgattttgca aaagtcttag tttagataag ggagtttttt tgcatatcct tctttattga
     2761 cttgtcttgc tctcgcaatt gccagcgcat attctggaat attgtctgta attgttgacc
     2821 cggcagcaat cgaactgttt ttagctacct cgacaggtcc gatgatattc gtgctagaac
     2881 caataaagct gtggtcgccg acagtcgtat gatgtttgtt ctttccatca tagttgacga
     2941 agacaacacc acatccgaca ttgatttctt ctcccagcgt agcatcacca acataagtca
     3001 agtgaccgac tttagttcct ttgccgattt gagcattttt cacttccaca aagtttccga
     3061 tatggacgtt ttcgccaatt tcagcttttg gtcgtaaatg tgcataaggt cccacatctg
     3121 catgtttctt gacatggctg ctttcaatga ctgagttttc aatgacgacg tgatcctcaa
     3181 tcctactgtc tacgattttt gaatgtgacc cgatgacaca atcagaacca atgactgtat
     3241 ttccttggat ttgtacacct gcttcgatca atgtgtctgg accgatttct acgcctgcat
     3301 cgatgtatgt cgttgctgaa tcgacaaagc ttacgccatt gaccatatgc atctggttaa
     3361 ttcgctttct catgatctca tttgctttag ctaacgcgat ccgatcattg actcccattg
     3421 attcttcaaa atcatccgtt tgataagcag caactgtatg gccttcttct tttaagattt
     3481 cgatgatatc tgttagatag tattcacctt gagcattgtt tgttccaact ttgcttaacg
     3541 catcgaacaa agcttcgttg tcaaaacagt aagttcctgt attgatttct tgtacaagag
     3601 cttcttctgg tgttgcatct ttttgttcca cgattttttc tacgatccca atatggtcac
     3661 ggatgattcg tccatatcct gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg
     3721 cattttttcc ttggtgatat tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg
     3781 tatcgccact gataactaac gttgttcctt tttttccttc caagaaagaa gcagcttgca
     3841 aaacagcatg tcctgttccc aattgttctg cttgtaacgc atatttactg cgttctccta
     3901 gttgtgcttt aacttgttct gctccgtgtc caacgatcgt aatcacttca tctggtttcg
     3961 tttcactgac ccgattaatg atatgttcta ccataggttt accagaaacg ggatgtaaaa
     4021 ctttatataa ttttgacttc atgcgggtac ctttccctgc cgccaaaata attgcataac
     4081 gtgcgtccaa ctgcgtcact cctaaatata gtttgctgat ttcagtttat cccagtatac
     4141 ccattttttc aacaaaacaa gtgattttct tttatcccag cgttttctgg ataaaaaaat
     4201 agatagacca taacgggcct atctatttgg taaccggtgc tctcctgcca actcctcggt
     4261 cacaagtcac actactcata aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact
     4321 tagagttaaa cggtaggctt acaacctctt cattaaacgt ttttcaatca gctgaccttc
     4381 ggtattagct caataaacgg caaaatatga ggagcaattt ttccgtttat tgagctaata
     4441 ctcaggacag gacgctgatt tcacaacctc tagataaacg gtgttcaaaa gccagtttct
     4501 cggtattaag ccaaatttat gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac
     4561 tactcgaaac taagcggctt tttcacaacc tcttattctg aaaaataatt tcctggcaca
     4621 accgtaatat ttttcgtttg agtatctaca tctttgacat aaagcagtga cgtataatca
     4681 tcgatggcgc gatgaccgtt gaattttgat tcggcaaata cagtgatgcc aacaagttct
     4741 gattcgaatt cttcaatcaa gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa
     4801 tcatccacta caaggacacg tgaaccacgt ttcaaacttc tcttagacag ttccatcttt
     4861 tcaattcttt cagaagatcc agacacatag ttgacactta ctgttgatcc ttctgttatt
     4921 tttgagtccc ggcgtacaat aacgaatggc gcattcagat aataggacac agcttgggca
     4981 ataggtacgc cttttgtggc tacagtcatt acagcatcga ttttttcacc aaggtattta
     5041 gaagcaatga ttcttccaac ttgacgcagc agttcaggtt ctcctaacaa atcagagaga
     5101 taaacatatc ctcctggaag cagacggtct tgttctgata gacgttctgc tagagattca
     5161 atatattttt tcgcctcttc atatgaaatt tcagggatga acaatacacc acctgcagca
     5221 cccgggattg tttccaaggt tccataccct cgttctttaa atgttttctt gatgattccc
     5281 aaatcttcac tgatagaaga tttagcagat tcataacgtt cggcaaagct tgttaaggaa
     5341 atcaattcat gcgggtgatt caataaatac tgtgtcatgt caactagacg ttcactgcga
     5401 cgtactttca cctattccaa ctccttttaa gaaattttat cgttttacat tatataagtt
     5461 tttcttcaaa aattcgagca ttttatgaaa aaataagaaa atagttcggt atttattaaa
     5521 ataaaaagaa gcctataaaa aatttttcgt ttttataagg cttcttttct ttataattta
     5581 gttatttttt cttctgaagg caaccaatat tcgtttgatg atatttacaa tcaggaacaa
     5641 agcaataaag actaatgtga ttgttgctcc tggaggtgta tctagataaa acgagctagt
     5701 tagtcctgac agcatcccta gaaatcctac acaaacactg atagcaatca cgacattgaa
     5761 gcttttgcct aatcgcatac cgattgctgc gggaagaacc atgattgcgg atatcaaaag
     5821 tgcaccggca atcgggatca tcacagcaat agccacacca gtaatcacat tgaacatcat
     5881 cgacatcaaa tgaacgggta gcccatccac gtgggcggta tcttcatcaa aagtcagaac
     5941 atacatcggc cgtttgaata aaaagaacaa tataccgatg gcaacgaata agattcctaa
     6001 aaagatgact tgctcccatg taatggtcac gatcgaacca aacagatagg attggatact
     6061 tgttgctgaa ttccctccgc tcaaattcat caatactaac gctagcgcca aaccaccagc
     6121 cattaaaatg gcaatggaga tttctgaata ggttcggtag atcgttcgca gatactccaa
     6181 tatcacagct gctaatacaa cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa
     6241 gaatcctaac gctacccctg ctaaagagac atgagaaagc gtatcagcca tcagcgattg
     6301 tcttctgatc actaaaaaca cacctagcat cggggcgatt ccggcaatga agatagcggc
     6361 aagaaacgct cttctcatga attcatatga aagcaacgcc attgagaatc ctcctttctc
     6421 accagtcgga tctgtctgtc cgcatactgt ttgatatctt catgatcatg ggtgatcatt
     6481 agaactgatt tcccatggac atgcgcacta tgtcggagaa gacgataaaa ttcatttctg
     6541 gattcttcat ccatacctgt tgttggttca tcaagaacaa ataagtcagg gtcagtagca
     6601 aaaatacgcg ctaaactgat tcgctgcttt tgtccgccag acaattcacc tattcgccga
     6661 tttcgcatat cccacatccc tacagcttct aaagcacgct gtacatgttg atgatctttt
     6721 tcagagagac gcttgaacca gcggcctctt ggatatcttc ctgaacggac taattcgatc
     6781 accgtactag gaaaacctgc attgaaagat gcaacttgtt gaggaatata accgatactt
     6841 aatttttttc cttcttgatt tttctcagca atctttatca ttccttttga aggtttcagt
     6901 aatcctaacg atgctttcac caaggttgac ttggctgctc cattttctcc agttaaaatg
     6961 acaaattcac ccgcatctac atgataagag acatcttcta gtacaggttc atcatcatag
     7021 taaaaggtca aatcagatat ttcgatataa cgcaccttac aacctccatt ctaaaactta
     7081 attgatactt tcttttaaag ctttcagatt tttttccatg acagaaatat aattttcgcc
     7141 tgctttgatt tgttcattag tcaagctttc taaaggattc aacacttcta gcttcactcc
     7201 tgtttcattc gacaatgtct cagctacctt cgaagaggca ttttcttcaa aataaatcac
     7261 tttgatgttg tttttcttca caaattcttt tagctcagct aagcgacttg gtgtgggttc
     7321 ctgatctggt gaaacgcccg aaatcgctac ttgttttaag tcgtattgat tcgctaaata
     7381 agcaaaagca gcatgctgag tgacaaatgt gcggtttgtt gcatctttta gctcatcgga
     7441 gtatttttga tccagtgctt caagcttttt gatataagca tcggcattct tcgtaaaagt
     7501 ttccttttta tctggatatt tttcgcctaa ttcttcagca atcgttctga cttcttttat
     7561 agctaatacc ggatcgagcc aaacatgtgg atcgtattca tgtgaatgac catgcccttc
     7621 ttctgattct tcatgttcgt ctgcttcttg cgattctaaa cggtcgattc ctttagctgc
     7681 ttcgatcatc aaggtctgtt tgctatccac tgaatccttt aacgaatcca caaaaaattc
     7741 catgtctgaa ctattataca cgaaaacatc tgcatcggaa atttctgctc tttcttttgc
     7801 acttggttcg aaatcatgcg gctccgttcc agcagggatc aaaagtttca cgtttccttc
     7861 atcccctacg atctcttttg taaaatcata catcggataa aaagtcgtaa cgatcgtcaa
     7921 atcctctttt ttgtctgctt ccttgttcgt atttccacat gctgcaaaca gtaaagcacc
     7981 tatcattacc gtagctgtca aaagatattt tttcatttat atgctccttt caatgaacaa
     8041 atcgtaattt tacgatttat taacgtgaac taatgtatca aaataaaaaa acacagtcaa
     8101 tagaaatcca tcaatttctg atttaagcat gtatattctt gattaaatcg taaaatggat
     8161 gagttgctgc tcatatctag ccatttcact acaataaaaa actgaagaat accattttag
     8221 gattcctcag tttttcatca cctattttac ttcttatatt ttattgcagg gttcgtacta
     8281 aataaacttc ctcacaaaaa ccttttaacc cattatatac tctctgcgct cttgaataat
     8341 gttgacacaa ggcaaaaacg gttggtccgc ttccactcat caatgcagca tctgctccgt
     8401 acttgatcat acgctctttg atttgatgga tgactggatg ccgctttccc gttatatctt
     8461 ctaaactgtt tcccattttt ttgatcatct gctgataatc ttgctctcgg atggcttcag
     8521 caagtccgtg gatgtcttga tgttggatgg cttgcgtatc tacttctcta aacactgtac
     8581 gtgtagagac actcattctt ggtttgacca acacaaccca gcactgtggc atagaaggta
     8641 atacttggat ttcttcccct ttgccaccga caaatgccgt acttccgtag acacagtaag
     8701 gaacatctgt accgacttcc aaaccgattt ctgccagttc ttctaacgaa cagcccagat
     8761 tccataattg gttgatccct cttagagcag ctgcacagtc tgtacttcct ccgcctaatc
     8821 cagctgctac tggaatattc ttcttaacaa agatcttgac accggttttg atattgtatt
     8881 tattttttag caataaagca gcttgataaa cattgttccg ttcatctacc ggtaaaaatg
     8941 ctttatttgt ttctacaatg attttgtctt ctgttatttc ttcaaaaaat agatgatctg
     9001 ccaagtctac gctcgacatc accatttcca actcatgata cccatcttgc cgtctatata
     9061 atacatccag tcctaaattt atcttggctg gcgctttttc aatcaattcc atcctctcac
     9121 ccattcgaaa agtctaagtc gcaagtattc tatcataggg aaaaataaaa gtatagctta
     9181 tgtctgccta gtggttgatt ttgtcatcgt ttcaacagct ttcacagaat tttctcttca
     9241 taatccaaac aagttctagt gattcttata attctgtgag cacttcttct gccaaactcg
     9301 gaacatttcc tttttctttt cctatcagac tgagtagctg catggtagca aatccgaaat
     9361 tacttccttt cctataagca aaataacgtc cttcccaatg atcgacatat tttaatttct
     9421 tttcataagc agactggaag gaatagaaaa aattaccata attatatacg atatgcatga
     9481 ctttttcttg aaagaaagaa aaatctgttt ctccaacatt agctaatgga gctaagccta
     9541 gattggcttc cgagtagccc attttctcgt atacaataaa cagattggct aacagatagt
     9601 cagctaattc ctcagattct ttaggtaaga cccgcaacaa atcatatccc gcctgcttct
     9661 tcgtcatcgg ctgagcggtg atgaagccaa cgactttttg atctttacgg acaataccga
     9721 caccgctaga taatacatat gatttatcaa atcgtcccac agagaagtat ttttctcgtg
     9781 caccttgaag ccatttttgt gaaacttcat ttacagcttg atgtaattct tccggcagtt
     9841 gatcgtacca agtaaaatgg tatccttctt tcatcaaacg ttgatattca agttgctgac
     9901 tcagccgaga caagtcttct gttgctagat caacaatccc tgcttcacct actttcgtga
     9961 agtgaaaacc caattcatga agcatcacta cgtagctttc tgatatctta taaaacgcaa
    10021 gctgatagcc taaacaatct gcttgtttca taaactgatt cgttgctgcc cgcatcattt
    10081 taggattgcc aactggatct cctaaaacaa agcatttgtt tcctttgatc tgataaccaa
    10141 aaacgacttg atcttggtcg tcttcttggt aataaaaata actgtaacct gacaagcgaa
    10201 gctgatggct tgtagctgtg cctccgtatg tttccaataa acggtcaaaa cggtcttttt
    10261 cgtactcact gccaagcttc gtagtatctt cagctaaata ttgataaagc gccactaaag
    10321 ctagcaatga gatgcccaaa ccaataagcc ctgagaacca cacatcatct gaaggaaaca
    10381 aaataaaatg atttcctgtt attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa
    10441 ttgcgtaaac gataaacaaa aagccgaaca agctagcatc aaagattata gctccccaag
    10501 aataaacgaa ttttgttcga taaaattctt ttctggataa ccacacagct aacagaatca
    10561 agacatatac caatatcaac tgccaagata acgtacgtgt gattgtattt aaaataccaa
    10621 aagatagtaa agcaatcgta ggcagaaatg cctttttgac ttttactgaa agtgctctag
    10681 caaggccgag taataaaaag ccaaccaata gattcactgt ctgatctaaa aaattgaatg
    10741 agaacggcaa taatacttga aatagccgac tgattgcaga cagattagtg attgttgata
    10801 gaagtaccat catgatcccc gcaaaataga cagcacttac gagcacgata tgcgcaacct
    10861 tttggaaaaa cagtcgcgga atgttatcta aaaatcgatt gattttgact cctgtatgtg
    10921 tgatgaacaa tagaagtccc gtcataaaag gtagaacata ataaaacaac cgataatata
    10981 atagccaaac tactgctaca tcttgccgaa cagacaattg actcattcct aagatcatca
    11041 aaacgtcaaa agtccccatt ccacctggga ccatcgtcag cattcctatc aatgtagcaa
    11101 tcatgaacat aggatagatc gaaagcatcg aaatatctat tctcatcaac ttgccgatga
    11161 tcaaaaatac cgcaagggct cccgtccatt gtccaaagga tgccagtagc agaccaagca
    11221 agccttttgg ataaaactcg aagaacaatg tctttctctt tagataagca aaaaagaaaa
    11281 tgactggtgc taaaaaacta ccgccgaaaa gccagatcca atagcttcga aaaatacttt
    11341 ctgactgaat aaaaaagaca tcaataaatg taagaaacga ccatacagac aaaccagtca
    11401 gcataaatag tgcgactttt gatacagtgg ctaaaaccat ttttctattt gtctgctttc
    11461 cataaaaact agcccgcaga cttgctccta ccacaccacc aaaaccggcg agattgttga
    11521 tcgtgtttgt tacccacgca gcaagaagaa actcttttct ttccattttt ggttttcctt
    11581 gtttttctaa gactctgatc gtcacccaat catacaacaa catcggagtg acacccagca
    11641 gtccagccag aatcatgagc aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa
    11701 tatcttgcca actcatgcca ttagcaatat ttgcgacttg atttgccaca aagactaaca
    11761 cggagccgaa aaaaatcagt tttaaaatca gactatgttc ctttatccat tgcagcatca
    11821 agtatcgttt atttttcaca ttttcccatt cctaacttgt atacttttgt gtcatacccc
    11881 aatgttatct tatttatttt aatttttcca ctttagacct gttctttgct tgcgatgata
    11941 gaaaaagaaa gatatcctaa tgctaaagga gaggataaca tgaaagtagg atttatcggc
    12001 acagggaata tggcacaagc tattattgat ggtttattaa aaaaaggaac agtctcgaaa
    12061 gaagaggtgt tcgtttccag tggacatttt gaaaatgcac aaaaatttgc tgctgaaact
    12121 ggcgtccatg catgcaaaag taatcaggaa gttgcatcac aatcagatat cgttctttta
    12181 gccgtgaaac caaaaatcat tgaaaaagta ttggaagaac taagagaata tagccagaaa
    12241 gtcttattca tttctattgc ttcaggaaaa tcattaatag atttagaaac agcgcttgaa
    12301 gatcctcagg cctccatcgt acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc
    12361 gtttctgcga tttgcaaaaa tgaagctgcc acggaggaac agcttcagca agctacgatg
    12421 atttttgaag caatcggcag cgtctatcct ttagcagaat cagatttcag tacattcatt
    12481 ggccttgctg gcagctcacc cgcattcgtt tacatgctga tcgatgcgat gggacggact
    12541 ggtgtactga atggtttgtc caaacagaca gccactgaga ttgctgcaaa agcaattatg
    12601 ggttcttgtc aaaaattcct ttcaagtgat aaaaatccat gggaacttgt agaccaagtt
    12661 tcttctcctg gcggtacaac tgttgcaggt gtagttgcct tagaagaagc aggattcatc
    12721 ccagcaatca tcaaaggaat caatacgacg atcgagaaag atcttgagat gttgaataaa
    12781 aaataatgat agcaatgttt tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc
    12841 gcggctcttc ttttgtattt tttattattt agcataatca gttgcacgag tttcccgaat
    12901 aacgattact ttgatgtgtc caggataatc cagttcttct tcgattcgtt tacgaatatc
    12961 acgtactaaa cgaacagcgt ctaaatccga gatttcttct ggcttgacca ttacccgaac
    13021 ttcgcgtcca gcttgaactg cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt
    13081 ttccagactt cttaaacgac ggatgtagtt ttctaatgat tcacttcgcg caccaggtct
    13141 tgctgctgag agcgcatctg ctgcagctac aaggacagag ataacagaag tagcttccac
    13201 atctccatga tgagaagcga tcgcgttgat tactactggg ttttctttgt acttggcagc
    13261 taattccgca ccgatctcaa cgtgagatcc ttcaatctca tggtcaagtg ctttcccaat
    13321 atcatggagc aacccggcac gttttgctaa ttggatatct tcgccaagct ctgctgctaa
    13381 gataccagct aattttgcaa cctcgaccga atgcttcaag acgttttgtc cataactagt
    13441 tctgaatcgc agacgtccga tgatcttgat tagatctgga tgaagtgtat gagcaccgac
    13501 ttcaaacgct gcctcttccc cgtattcgcg aatacgttca tccatttctt tacgagattt
    13561 ctcgaccatt tcttcgatac gcgctggatg gattcgtcca tcttgtatca gtttttccaa
    13621 ggtcatccgt gcgatttctc ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg
    13681 tgtatcatcg atgattaaat cgataccagt cagcgtctca agcgttcgaa tattacgacc
    13741 ttctcgtcca atgatacgac ctttcatttc atcattcgga agggtaacga ctgaaacagt
    13801 cgtttctgaa acttgatctg ctgcgcagcg ttgaatcgct aatgataata agtttttcgc
    13861 tttgcgatct gcttcttctt tggcacgctg ttcagattct tttaccatta gagttaactc
    13921 atgattcagc tcttcttcag tcgatttcat gatgacatct cgtgcgtcct cttttgataa
    13981 accagcaatt ttttctagtt ctttttgttg atcttcaatc attttttcaa cgtctttttc
    14041 tcgctcttca attaattgct gttttgaact aagtgcttct tctttacttt caagtgagtt
    14101 ctcgcgtttt tctaacgagt catctttacg attcagcgtt tgttcgcgtt gaatcaaacg
    14161 attctcttga gattttaatt ctaacttact ttctctcagc tcactttcaa cttcagaacg
    14221 gtatttctga ttttcttcct tagcttctaa caatgcttct ttttttagag tttctgcttc
    14281 tttttttgca ctatcgatga ttccagcagc tgatgattgt gcaccagcta tttctttctc
    14341 gtgacgtgac tttgcgacca taaaccctaa accaagaccg acaattaaac cgatgatagc
    14401 gaggagaatg ttgaatacca taaaatccac ctccatacta tctttttcat ttttatcatc
    14461 tatacagctt ctatgataaa ttattctaaa ctcgtcaata tgcatcttcg catatatgtg
    14521 tacaaaaaac atgcacaact ttattctaat gtttgtaccc cgtagtgtca actttaaata
    14581 aacaaagaaa cggctttcta cttattcatt aaacgatggt ttttaaaata aatgacacta
    14641 gtttcatata ggtaaacctt taaattgaga aacttttcta ttaaattatt ctttgtagat
    14701 gaacagatat ttttatttta tgtacccact cgtataatta aataactcac gatttcttta
    14761 ttcaataaaa aaacggcagg tcaaggagag tacctactct tcagaccagc cgtttttgtt
    14821 tatcataatt tttattcttc tactaaaggc aattcttctt gtcctttttc atcttctggg
    14881 acagcgactt cttcaccaat accataagct gctctaacta gagcagaaac ttctgccatc
    14941 atttcaggat gattagccat atagatttta gcgttttccc gtccttgacc aatccgatct
    15001 tctttataag aataccaagc accgctttta tcaacaatgt ctttttctac tgccatgtct
    15061 agaagttctc cttcttgtga gatccctaaa ccatacatga catctacttc agcgattttg
    15121 aaaggaggtg ctactttgtt ttttacgact ttgatctttg tacggttacc aacaatatct
    15181 gtaccttgtt tcaattgttc tgcacgacgt acttccaaac ggatcgttgc gtagaatttc
    15241 aatgcgcgtc ctccaggagt gatttctgga ttcccaaaca tcacgcctac tttttcacgg
    15301 atttggttga tgaaaatagc gattgttttt gttttgttga tcgaaccaga gagtttacgc
    15361 aatgcttgag acatcaaacg tgcttgtaac ccgacatgtg agtcacccat ttcgccgtcg
    15421 atttctgctc gtggaactaa agcagcaact gaatcgacta ctacgatatc tacagcccca
    15481 cttgatacta aagcatcagc gatctctaga ccttgttctc ctgtgtcagg ctgtgaaaga
    15541 agtagttcat cgatattcac acctaatttt tgtgcatatt gcggatctaa cgcatgctca
    15601 gcatcaatga aagcggccgt tccgccattt ttttgtactt ctgcaatagc gtgtagtgca
    15661 actgttgttt tacctgaact ttcaggtcca tatacttcga tgatacgtcc acgggggtaa
    15721 ccgccgacac ctaaagcgac atctaacgca agagagccac ttggaattgt agagatttgt
    15781 tggtcgattt tttcgcccaa tttcataata gagcctttac catagctctt ttcaattttt
    15841 ttcagtgcag catctaaggc tgctttacga tcatctgcca atacgataat cctccttata
    15901 tttacaaatc agagcaacat ttcattatcc ttatcatatc ttttttagtg aaaaaaagca
    15961 agaaaaaacc gaacaaatat tcgcatttat cattttctta aaagctgttt tctcaaaaga
    16021 tcaaatcctt gcataaccgc attatatctg atagcagcac gatctctggc aaagtgatat
    16081 ttttccgaaa ccacgccgtc tttagatgaa atagcgatcc atactgttcc tgcagattga
    16141 ccttctaacg tgtccggtcc agccactccg gtgaaagcta cactgtaatc tgttcttgct
    16201 atctcacgtg cttgaatggc catctgctcc acacattctt tgctgactgt tccatattct
    16261 gctaatagct ccggatcaat ctccagaaaa ccagcttttg tttggagcga gtaggtaacg
    16321 aatccgcctg gaaatacttc agatacacca gcaatgtcgc ctaatgcggc ttggaaggcg
    16381 ccggctgtca aactttccgc tgctgttaca gtctgcttgt tttctttcag tagttccact
    16441 acgacttttg ctagcgaatt atcatcgccg tatccataaa aatattcccc tactcgttct
    16501 tggatttttt cttctaatgc taaaagagct tgattccctg cctgaacatc atttgttttc
    16561 actgtcagtc gtaatgtcac ttcatttggt ttggcatatg gtgcgatcgt tggattgatc
    16621 tgtgtctcaa tcagatcttt tagctcagtg accagtcgcg attcaccaat cccataaaag
    16681 cgcaaaactt tagaaattag tttttcttca gaaggaaaac gttcctctag taaaggacgt
    16741 acttgttcca caaacattgg tttcaactca ttaggcggac cgggaagaag gatatacgca
    16801 tgtgtatctg tttgataaaa agtccctaaa gcaagccctg tacgatttgg tagaggaacc
    16861 ccgccttcga taatctggga ctgttgcaga ttgtttttgg tcatttttcg atgggttgtt
    16921 tcaaaatatg ccaataattt tttgtatcct tccgtatttt gtatgagaga cttaccgagg
    16981 tgagccgcag ttgcttcttt tgtcaggtca tcttctgtcg gtcccaatcc gccacataag
    17041 agtatgagtt cacttcttgt ttcagctaga gcaatcaact cttctaaacg ctgctgatta
    17101 tctcctacaa ctgtttgata ataaacttcg atacctagat cagctagctg ttctgacaag
    17161 aaagtggcat tcgtattcac gacttgtcct agtaaaagtt ctgttccgac agctattatt
    17221 tctgctttca ttacttcccg ctcccttata tagtatacgc tgtattttta tattttttta
    17281 tttaaaaaga gggcaaggag ctgtgacaaa aatcttgtca cagctccttg ttccaaataa
    17341 acagtgttct cctgccaaaa cctcggtcat aagtcacaat atacataaaa catgaaaagc
    17401 tgttttttga aattatccct tgtgactcag agttagacgg caggctcaca acctctccac
    17461 taaacgatac ttacattgat cctttgaaca caccgctgtt tttgatgaag taatccacac
    17521 ctgaatagat agtaaagatc agacaagcat aaagcatgat ttgatctact ggaataccga
    17581 tcaggctgaa tgggatatta ttgataaaca gcaagataat agcaaccatt tgtgtagccg
    17641 tcttgacttt tcccggccaa gctgcagcca tgacttctcc atgttcgaca agtagtaaac
    17701 gcaagcctgt gacggctaat tcacgacaga caatgatcgc tactacccaa ccaggggcct
    17761 ttccttggtc aaccaacatg ataaaagcag tcataactag cattttatct gccaacgggt
    17821 ccgcaaactt gccaaaatta gtgacaaggc ctcgcgcacg ggcaattttt ccatctaacc
    17881 agtctgtgat actagctaaa gcaaaaataa ctgcacctac tagctgtgtg acagccagtg
    17941 tggtgtctcc tacgttaaat tgtccccaat ctaaaggtaa acctacaacc aaaatgaaaa
    18001 tcgggatcat acaaattcta agtacagtta atttatttgg taaattcaca ctatcgactc
    18061 ctttcttccc tattctacgt gactatcagc gaagtttcca ccgatattat ttacttttcc
    18121 aaatgaattt attcaaagga gtatttttat tgaaattgat ctttttgaat taacgaagaa
    18181 ggaccgcgac acagatttgt cacgatcctt cttttttata cctacaagta aacagatgcg
    18241 taaactaatt tatacgatca ttctgcgtat tgaagagtaa ggttcacatt ttttggactc
    18301 tgattgtttt cccctggatt aactggtacg gattctccat tcgctttgat cgttgcattg
    18361 cttgctgcac caatcgtgat ggtcgcattt gttgctgttt ccggtaacac ggtactctgt
    18421 gtttcatttg ctgccagtgt cccttgataa acataggcat tgtctactag cacacctaac
    18481 catacacgat tgacagcagt aaattcaagg gttacaggct tggtagcgtc tgtgatattt
    18541 actgcgatgg cactgccaga atcttctcct gtagctattg ccattttctt ttcttcactt
    18601 gattttgttg ttgattctac tgtagaagac tctttggtct gcgtgctttg ctctgaggaa
    18661 gaggactcct cgactgatcc ttctacttta agcgaagaag ctgtgtctcc gattattgga
    18721 tcagcttgac gatcttgcca agtcatatag cccacgacaa cgacaatcgc caaagcaacc
    18781 aatcctaata aaatgacagg aagacttgtc caaaagcgac ttggatgcga ttcttcctga
    18841 tgcattgctt ttctagaagt acttactgtt tcaggctgcg gacgttcagg gaccgatcct
    18901 gtcaatttgc ttttcccatc aaaaacatcg actaaatggt ctccatcttc tcctacagct
    18961 tcagcgtatt gccgaataaa tgcccgcacg taaaatttac caggcaattg gtcaaaatca
    19021 tcattgtcga ttgcttccaa ataacgtttt tgaatttttg taatctgctg taattcatct
    19081 aaagatattt ttttattcag gcgtgcttgc cgtaattttt ctccgatggt ttcaaaagcc
    19141 actcgttcat cttctccagt ctgtttgatt ctccgaagca tctgctgttg caacgaaaga
    19201 cgttatgttt gggtgctgtg acaaaagtca tgtcacagct ccttttttcc gaataaacat
    19261 tgttctcctg ccaactcctc ggtcacaagt cacaatatcc aataaatata agaagctgtt
    19321 ttttgaactt gttccttgtg actcggagtt aaacggcagg ctcacgacct ctttcttaaa
    19381 cggtgttcaa tcagctgttc ctcggtatta gctcaaaaac cggcaaaata taaggagata
    19441 tttttccgta tgtttctcta atactcaggt caaaacgctg atttcacaac ctcttcctta
    19501 aacggtgttc aaaagcttgc atctgcggta ataagtccaa ccaagttaaa aacattaaga
    19561 agctgttttt acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctt
    19621 ggtacacggt gttccagaag tagcttcttc ggcaataagc cgaaatatca caaaaatttg
    19681 agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct gtcacaacct
    19741 ctttgattac ttcgtttgat tttattttaa tataagttga ttaaaagaga gcatgatttg
    19801 ttttattttc tcactaattt ttccaacaca actaagaata ccataaaagc tgattttgga
    19861 ggaggttcct actacaagtc taaaacgaaa tttaagactt ttcctcataa aatactggtt
    19921 tattttggtc tcatgtaaaa ctcgctgaag gcctcttcac ttataaatgc ttccccagct
    19981 gccagtacgt ctttcatttg gatcgaatcg atgatttcag gaagatcaaa taaagttcga
    20041 tcgccaaata aactttgcgt aaattgattg gcaatatatt cgatcgaatt taatgattgg
    20101 aaatattgtc caagcatttt cttcttcagc aaatcgagat ttgtttctga cacttccgga
    20161 tcatcagcga atccaagaat gatttctttg actttttctg ctgctttctc tggttcgtcc
    20221 gtatctccgc tgaagtccgc aaagtgaaat tcacgatcca agctgaattc aaaaccaaag
    20281 ctgtcatcga taattccttg attgtacatc gctagatagt ttcgagaagt attgcctaaa
    20341 atcatttgga acaacagatt gattgctgtt ttatagcgta acagttctgt tccttcttgc
    20401 ggcaatgtgt ctaatccttt aataccaagt acaaatttat ctcgtgtaat ggctgcttcc
    20461 aatgcacttt gtttgatgat ttcttttgtg ttttcaggga aataacgtac aatttcttgc
    20521 tttggaggga aattttttgc ttcttggttt tcccgaataa gtttcatcaa tttctcaggc
    20581 tccatcttac caactacaaa taaaaccata ttgcttggct gataaaacgt ccgatagcac
    20641 gtatacaagt cttgagctgt gattttgtcg atactttcaa ccgtgcccgc aatatcgata
    20701 tgcaatgggt gtgtaggata caagttattt agtatgccaa aaaacatccg ccagttaggg
    20761 tcgtcttcat acatttggat ttcctgaccg atgattcctt tttccttgtt tacagtttct
    20821 tctgtgaagt aaggtgcttg tacaaaatcg atcagagtcg tcagattctt ttctacctga
    20881 tccgtcgtag aaaacagata gctggttttc gtaaaacttg tgaaagcatt ggcggaagct
    20941 ccttgtttcc caaataattg aaagacatca ccatcttctt tttcaaacaa cttatgttct
    21001 aaaaaatggg caattccatc tggaactttc accttttctt tttcaccata gggaataaat
    21061 tcgttatcga tcgaaccata attcgtactg aacaaaccat atgtcttgtg atagtcattt
    21121 ttaggcaaca aatacacggt caaaccgttt ggcagtactt catgataaag tgtttcattg
    21181 atttgctcat attctgtttt attcatttgc atttcctcct gctaaaaaga agattgcctg
    21241 caattcgatt tgctcagcta cttgttgtat ctctttgatc gttacgctct ccatacgttt
    21301 caaccattct tcatcagata attttgtttc cggcagccag ctgtccaaaa aagaagcttc
    21361 gattgccgct tgcggagagt ctagagaaag cagatattgg tttctcagca ttgcttttgt
    21421 ctgagacagt tccaactctg ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat
    21481 cagatgaagt acttgatttc ggttcttttc atcgataccg gtttggacac tcatgaatcc
    21541 tcggaacgta tccacgctac tagaggcata ataagctaga ctttctttct ctctgacatt
    21601 catgaaaagt ttagagtgag gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa
    21661 acgttctggt tcatcgtaat acacatttgt ctgataagct aggttcagct ttgcttgaac
    21721 gattggctca cgtacttgtc gttccttcac gatattcact tgaggttggg tataaaacag
    21781 atctggataa actgtttccc gcgactcaaa tggtaattgc ccaactgctt cagctgcttt
    21841 gtccggatca acatcgccga caacaaaaat gtcgatttga tcatttgcca tcatttcttg
    21901 atagtaggac gctagcgaac tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc
    21961 tgggatcttt tgttccgggc tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa
    22021 agtttgttta tcttccttca aactttccaa atatagacgc agattgttct tttccaagtc
    22081 aaacgtcaac tgatcaaact gatgattttt aatatttgga taaaataaaa cctcttttaa
    22141 aaaatctacc gcttgagaaa aaaggtttgg atcattgaca tattcaccat tcacaaaact
    22201 gatccctgcg tttagccaat gtaaatttcc tttttttcta actgataatc caaagcttgc
    22261 gccataaagc tctgcaagtt gcgcacttaa ctttgtctga tccgaataat tcaaactatt
    22321 tgtttccaac atgctgctga gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc
    22381 agtaaaacgg ataaaaatcc ggatcgtttt gtattgtttt gttggtaaga catgaagatt
    22441 cacgccttct gccaattgat acaccatatt tatatgctcc ttttcacagt tgattgcccg
    22501 cttactcttt taatgggtca acctgccttt tttacttatt cctctgcttg aaatttataa
    22561 gttcaggcaa ttcgccgttt tttctaaatg atgttacact ttatagtata gcatagatgt
    22621 tttttatcaa aagaaacaga cggctaaaag cgtatattgt ttttttattt tttatttttc
    22681 gatatactaa agacaaataa aagaagggag ggtcattcat gatcaaagaa ttcaaagagt
    22741 tcatcatgcg tggagatgtc ttggatcttg ctgtcggcgt tgttattggt agtgcgttta
    22801 caagcatcgt aaaccaagtg gtgcaaggct tgatcacacc actaataggt tggtttgtcg
    22861 caatgatcac aggtacttct gatttagaag gagcactttc aattcttgac tggtcgccga
    22921 caaaaggcgt cacatttgcg tttggtaacg ttattagtgc tatcattaca tttctgatca
    22981 ctggttttgt cttattctta gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca
    23041 aagaagagca agtggaagtg gaagaaactc ctactgcaga agattatctt agtgacatac
    23101 gcgatcttct tgccaaacaa gtggcagaag acaatacaca tccagtagag caaacaaatc
    23161 tttccgatac ttctaaataa taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg
    23221 ctttcttttt ttagattctt aacttgctac ttgttccttt ttcatgtcga tatgtggaat
    23281 atcatcttcc aaatacacat ctgagattgc cttgaatcca aacgactcat aaaaagcttg
    23341 taggtattct tgtgcgccga tcacgattgg tttttctgga aaatttttct ggatcatgtt
    23401 aatcgtttct tgaacaatct ttcttcctaa accatcttta cggttgtcct gatgaacaag
    23461 gacacgtcca aaatggatac tctccgcttc ttcatatact cgcgtgtagg caaggatctt
    23521 cccatcagta tcttgaaaaa acgtatgcca agcttctcca tcaatgtcat caacttcttg
    23581 ataaggacac tgttgttcca caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa
    23641 ctctgctgtt gacaattctt caaatttctt tacctgatat tccactaagc aaacgccccc
    23701 tgctttttta ttcttagcat accgattcgc acacaaaaaa gcaaacgaac cttacgaatc
    23761 tcaggctcgt ttgcttttta aactgcttca gttaaaaatt cgatctcaac tgtccgagta
    23821 agtacatctg aatagctgta agatactcgt tcaaaagaat tttcttcagg atccaaatca
    23881 acaacgaata ctgaaggata ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt
    23941 cttcctgtct gagcaaccaa catgattggg ctgccgatac gaccttctaa atctttcttg
    24001 attgaagcta aagttgttgg catacagttc acctctacta tcaactatac cacatatttt
    24061 taaaattttc aagtttacca taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc
    24121 attaagattt ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt
    24181 tttactctcc cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg
    24241 tctacaaaat caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac
    24301 tggatttcgc aattttcgat tgcttctttt aataaaagat gctgaattgc taaaggttct
    24361 tgcaatgtga tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag
    24421 acttcatctt tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt
    24481 tgattgctta taacgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa
    24541 gttctcaatg cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa
    24601 tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg
    24661 gcagcaaatg cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa
    24721 taattcctcc ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat
    24781 tagaacgata tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt
    24841 taactgctct tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt
    24901 ttcttgggct attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt
    24961 tcgtaatgct ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt
    25021 cacttgtgtc aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt
    25081 ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc
    25141 cggaactagt tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt
    25201 tgataaacga tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg
    25261 gacaagttcc ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt
    25321 catggtctac tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac
    25381 actggcattt aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc
    25441 ttttttcaat cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc
    25501 tttggcattc catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc
    25561 tgtttctttg agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg
    25621 ttcgactgcc ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt
    25681 tggtatgatc acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt
    25741 gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt
    25801 tcgttcaatc agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc
    25861 ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg
    25921 cacagcttgt tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc
    25981 ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc
    26041 aaagacgaaa ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc
    26101 agtttgcttt ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg
    26161 atgtttgttt gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga
    26221 tcaattcttc catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga
    26281 accctgttgc gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag
    26341 catttcttcc tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca
    26401 tttgctgaat caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca
    26461 gcttattggg ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa
    26521 tcgcatctcc aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc
    26581 tcttctccat cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa
    26641 atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc
    26701 gatcaattgt tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat
    26761 cgaaagccat tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg
    26821 ctggtctaga taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc
    26881 tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc
    26941 gattttatcc gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt
    27001 gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact
    27061 gtagcggatc ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc
    27121 aacgtttttg atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc
    27181 atcgtcttcg ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc
    27241 tgttttcgct tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc
    27301 gccaccatgg atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat
    27361 atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc
    27421 ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg
    27481 ctgacttgct ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc
    27541 aaatttacgg gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac
    27601 caacacttga ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt
    27661 agcaggttcg acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc
    27721 aacttctggt gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc
    27781 cgtgaaattc gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt
    27841 atcgaaagca atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc
    27901 gcagacatac ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt
    27961 caatgtattg tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg
    28021 acttttgctg gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca
    28081 cctgcaccga ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca
    28141 gagagcatgg ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg
    28201 cctaatgtta cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg
    28261 acgattccca ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc
    28321 tcaacaccag ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg
    28381 tgctgatata aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc
    28441 aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct
    28501 cgggtaaacc aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc
    28561 ttcttataaa gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc
    28621 gtggttccac ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt
    28681 tcttggctac tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc
    28741 actcccagag gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt
    28801 gtaatgatca gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa
    28861 tgtgctaatg atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc
    28921 atttgtcctg atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt
    28981 tctttttgaa cagctttgat ggcagctttg acagttggag catctactac ttccatttgt
    29041 tctagctgtg ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct
    29101 tttgctgctt cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt
    29161 tctgcagcat agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt
    29221 gtcttttcat ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg
    29281 tcagtaaatg catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt
    29341 ttcgcatcga aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat
    29401 tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag
    29461 ttgaacattg catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt
    29521 gattcgtcac gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt
    29581 ccgaaggttg gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg
    29641 gcaatatggt catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca
    29701 acagcaaaat tataagttgg cataccatcg cgtttttgga tgacaaagtc gccaccgata
    29761 ttatcggatt cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg
    29821 cgaggcacac ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct
    29881 tcaggtgtca agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt
    29941 gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta
    30001 gcaagcagct gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg
    30061 ccgtattctc caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt
    30121 tccaactggc ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga
    30181 ataataaagt ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca
    30241 tttccaatat gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt
    30301 ttcttcctct tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct
    30361 tctcaaatat catttattta aagccactca gcacaaattt taccttttct aaggtaaata
    30421 gtaaagccaa ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg
    30481 tttagtcttt ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt
    30541 agcaaagatc atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg
    30601 ttcattcatg taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc
    30661 tactccttgt tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg
    30721 gatgacgact ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg
    30781 gaattcagag actttattca agttatagtc attggttaca atgacaccat ctaaaagctt
    30841 agccaatttg atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat
    30901 ttcgacagat ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc
    30961 acgcacacgt ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa
    31021 attagggatc atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc
    31081 gtcaatgatc acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg
    31141 ttctaacagt tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga
    31201 accaaaaact ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc
    31261 taagatgatc atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta
    31321 aagaggggtc gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa
    31381 gagaagataa gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga
    31441 gatatgtttg gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt
    31501 ggtaaatgta ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg
    31561 taaaaatgaa atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt
    31621 ttgcatcgtt tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa
    31681 cgtttcagcc aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc
    31741 taagttgttt ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg
    31801 ttgttcaata tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca
    31861 ttccgttggc tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa
    31921 atcaatcgct ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt
    31981 ctgaagaagc aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa
    32041 atcaagacct gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg
    32101 gatctctacc aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc
    32161 accgtctagg cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg
    32221 ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg
    32281 caaaatccga aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg
    32341 ttctaacatt cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat
    32401 ggctatccca tttgttttag cggttttgag tagttctgca gtggtttctc ttacttggct
    32461 gacacttcct gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat
    32521 aacataatca ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc
    32581 gtatagataa aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc
    32641 tgcgctttct tcgccggata catataagac ttttccgcct atggctgcta attgctgaga
    32701 aacttgtaac agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga
    32761 ccctggcacc acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg
    32821 aggttctttt ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa
    32881 acttgtccga gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca
    32941 ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca
    33001 aacaaattgt acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag
    33061 acattaaatc aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct
    33121 tgacgttgag cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg
    33181 ccgatacgct cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac
    33241 atgatatggc cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg
    33301 tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat
    33361 tcatcttctc ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt
    33421 tcattttctg atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag
    33481 cctgctttcc agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca
    33541 gcatgatgtg tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact
    33601 tcaaatcctc tttttctcac cggttttcct ccctaaataa actactccta ttctaacata
    33661 tccgaggctg taaaagactt tctttacaaa ttcttcaaga aattctgcta tcttaaagta
    33721 aaccattaat tcgttctttt tccaaacgac tgcaagttgt acaaaaaaac tattttttac
    33781 atgactttac tcgtcaaaac aagtagaata gaacgaaatt aatgagtgga tatttgattg
    33841 aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca
    33901 agtacattga tttatcccaa tggaaatatc aatcttgcgg caatcgatca gttagctttt
    33961 gtcctttctg atcttagaaa tcggggaaag gaagtgatct tagtctcatc aggagctgta
    34021 ggcgttggta tgcataaatt acatttgtca gaacgtccga ctttgattcc tgaacagcaa
    34081 gctgcggcgg ctgttggtca agccgaactg atgaatatct ataatcaaag attcagtgta
    34141 tataatcaac agacggcaca gatcctcgtg acaagagacg tggtagatta tcctgaaagt
    34201 cgtaaaaatg tgaggaatac attggaacag cttttgatta tggacacgat ccctatcgtg
    34261 aacgaaaacg atactgtagc agtggatgaa ttagatcatc tgacaaaatt tggcgataat
    34321 gatcagctgt cagccatcat ggcaaaactt gtcgcggcag accttttgat cgtcctttct
    34381 gatatcgacg ggttttattc agataatccg actacaaatc ccgaggctca gatgtatcgc
    34441 tatatcgata aaatcgatga aaagattctg gcacaagcag gtggtgctgg tagcacattt
    34501 ggaacaggcg gtatgcagag taaattaaaa gccgcttcta ggatatttga agcaaacagc
    34561 gcaatgattt tagcaaatgg aaaaaatccg gcaattattt ttgatattct tgcaggaaaa
    34621 gaagtaggta ctttatttaa ggaggacttg aaatgactga cttgatgcaa ttaggacaac
    34681 aggcaaaaga tagcgcgcaa caactagcac ttatgcctac aaaccgcaaa aatgagctac
    34741 ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc gatcattgaa gcaaatcata
    34801 aagacttaga aaaagcagtc gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc
    34861 tgacacctga gcgaatcaat gccatggcta cagagatcga aaaaattgct tcgttagacg
    34921 atcctattgg aaaagtagat gagatgtgga cgaacaccga cggattgaga atcggcaaaa
    34981 agcgcgtgcc actaggcgtg atcggcatca tttacgaatc tcgtccaaat gtcacgacag
    35041 atgcagctag tctagcattc aaatcaggga atgccgttat ccttcgcggt ggcaaagaag
    35101 cattcttctc gaatcaatta ttagtccaat tattgcagca agtactggtc agtgctggcg
    35161 aatctcctta tgccatccag tttgtcgatg atacttctca tgaaactgca ggacagttga
    35221 tgcgattgac agaatactta gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac
    35281 gagtcaaaga acaggcaacg gtacctatca ttgaaacagg tacaggaaat aatcacgtat
    35341 atatcgataa agaagcacag ttatctatgg cagtgaacat catcgtcaat gcaaaagctt
    35401 cccgtccatc tgtctgtaac gcggcagaaa cattgctgat ccattctgag atcgcacctt
    35461 ttttcttgcc agctattgaa aaagaactgg tagaacacgg ggtctcttta cgtgcggatg
    35521 ctcgtgcgtt agaatatcta gagacggctg ctttagcaga agacacagat tgggatactg
    35581 aatatctaga ttatatcctt gctgtcaaag tggtcgattc tttggatgaa gcaattgcac
    35641 atatcaatcg gcataatact aaacattcag aaacgatcgt gacagatagt tatgcggcta
    35701 gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt
    35761 ttacagacgg atcggtattt ggttttggtg cagagattgg tatctctact caaaagttgc
    35821 atgcccgtgg tccaatgggg ttaaatgaat taacttccac aaaatatatc atttatggcg
    35881 atggacaaat ccgcgaataa tgtttcgtgt gaaacattat tcccgccttt tgcctttttt
    35941 ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt tgaaatttta atgatttttt
    36001 ttatttacct tatttctctg aatatcgctg cttttctggg agtcggtatt ttatcccttt
    36061 tctttcaatt caaaaaacga agcataggga gtcaacggga aaaatggtcg cagtattttg
    36121 acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat tagttacatg gttgcattat
    36181 gcttattagc gacaatcaat tactattctt ttttcgatca ttcaatcgct tatacgatta
    36241 cgctactgat tgctgggatt tttcacttat cttataaata tcagctgaat aaaaaccact
    36301 tgaatcggac tttccgctaa aaaatatccg tacgataagt agagtgcctt gaagatcggc
    36361 aaaaaactgc cggacttttt agaggctgtg acaaagattt tgtcacagcc tctttttcca
    36421 tataaacggc gttcgcctac cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg
    36481 aaaatccgtc aaatgtttcg ccatcataat aacgaagcag ctcatccatg gacaagttca
    36541 tcgttttttc tttttcttct tccgctgatt cagccagtag ctgttcccga tacacctgat
    36601 acataccagc tattttttgc tgcatcgctt ttctagtttc accttccgca ttgattattg
    36661 gcaattcttt gatatagcca cgataaatca accgatcatc tgaaaattca atgggtaatt
    36721 caacgagtgt caacccgact tcctgaaaat attcttccag catctattat ccccccattc
    36781 tttttcttaa atgaatttta gcttacctac tgaaaatttt ccagtttcat tattttgaga
    36841 aaaaaaggga atgtgacaaa aatcgtgtca catccccttt ttccgaataa atggtgttct
    36901 tctgccaact cctcaatcat aagtcacaat attcaacaaa catgagaaac tgttttttga
    36961 aattgttcct tgtgattcag agttaaacga cagtctcaca acctcttggt aaacggcgtt
    37021 caatcagctg accctcggta ttagctcaaa aaacggtaaa atatgagaag ctatttttcc
    37081 gttttgtttc tctaatactt aggataaaac gctgatttta caacctctgt taaacggtgt
    37141 tcaatcagct gtccttcggt attagctcaa aaaacggcaa aatatgagga actatttttc
    37201 cgtttgtttc tctaatactc aggacaaaac gctgatttta caacctcctg ataaacggtg
    37261 ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatatga gaagctattt
    37321 ttgtttggct gttcttatga cttgatgcag gacagctttt tcacaacctc tgatttctta
    37381 ttcttcttca tttgtagcaa aataattacg gtgataaatg atacaacata cactgataag
    37441 aacaatggca cctgcaaaat aaaacgcata gctttcacca atatgttcac caatcacacc
    37501 tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca aaactatagc tggacgaagc
    37561 aacgtttcgt tgcagacctg gtatttccat agcaatcgtc gtcaacagtg tattgataat
    37621 tccttggaaa aatcctgcta acacaatgct gatcggtaca aggactggca tagaagttcc
    37681 agctcctaat aacagcaaac aaataatgaa taagacaaat gctgctaaaa ttgtccgata
    37741 agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc gaagcaatag ccagaagcac
    37801 accccagcca aaaaatacaa aaccgacttc taattcagaa tagccaatca ataaaaatgg
    37861 cgcatacgca agtaaagtaa agaatccgaa attatataac aatgcgatta gtccaactga
    37921 acgaagttta tgattgctta acgctttgac accttcccaa aggcctactt ttctctttgg
    37981 tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa ccgcaaaaca tcaaaaatgc
    38041 taccccaaaa aatggataac gccatgaacc actgcccaag accccaccga ctagagggcc
    38101 aacagccatt ccgcagccaa gtgctgcttc atacatcatg attgcttttt ctgtgttacc
    38161 aactaaaata ctgacgatcg ttgctaaagc agtagagaca aataaagcat tcccgacacc
    38221 ccagccggca cgtaacccaa tcagcattcc gatattccca gataatccgc caagaccagc
    38281 gaatacaacg atgataaaca atcctgtcat caatgttttt ttcaaaccga tccgactaga
    38341 taagaaacct gtaaatagca tcaccacacc agtgactaac atgtaactag taaataacag
    38401 ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc gtttttaaga ttgggtctac
    38461 tagacccact cccataaaag cgatcataca ggtagctgct acaactagcg ctgaactttt
    38521 cccctttgtt tcttcatttg tttgttcttg tatatctatt tgattctcca atatttccat
    38581 ccctttctct ctattagcat catacatgat ttattttaca tgtcaatatg cacatgtaaa
    38641 acgtggaaac tttactgtga tataataaag aaaataagac gagaggtagg atttttatga
    38701 atactttagc ctatatatta ttatgcgtgc ttttatccaa accacgttct gggtatgaat
    38761 tgaagcagct gatcacaatt ttttgggaag cccatcacag tcagatctat acaacgcttg
    38821 ccaagttaga ccagcagggt tatgtgaccg ttttggacaa agacgagcac tctcaaaaaa
    38881 agatctacca cttgactgat gaaggacgtg ctcttgtaga ggaatggatc aaagaggaaa
    38941 ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat ctatgctttt tcgacgctcg
    39001 ataaaacaac agctactgga ctgctattca ctagagaaca acagctgaac aaaatcatgc
    39061 aaaaaaatca aaaaaaattg aatgacctct cgctagacaa gaaacaagaa tttggacgtt
    39121 atgttgtgat ccagcgcaga attatgcttt gtcagcagga actccaatgg tgtcagcaag
    39181 taagagaaca aatgcagcag ttttttgagt aagggataaa cagaaccttt ctagaaatat
    39241 ctattgaaga gcaaattatc ttcaataaaa gagcaataca gttggaaaag aaaaagcgat
    39301 ccgaacgaca ggccaaaacc tatcgttcgg atcactattt ttctagaact gcattcaaga
    39361 gactatgaca aaaagcatgc caaggccttt tttcaaataa cagtgttcca tcattcatta
    39421 ctttgaattg cttttagcac acttcttgaa agcgggccaa cgatgatcaa ctgcaacggt
    39481 aaagcggcaa tcacattcat tttccaagca ttcatataag cagagaataa ttgatcaggt
    39541 attccttgtt ccatgatcac accgaataaa gacatacatg tcaccattcc taaaaccatc
    39601 aagcatgaaa tagttaagat catttggacc ttgctttctg gatttactgg tagtttaaag
    39661 gcaatttttt tcgccagcac accgatgatg aagacatcca aaatgaaagc caccacgaat
    39721 ccaggcacta gaccaatcaa caaacttgat aaatgaagat cttgatgcag ccataaatta
    39781 tacgcgctca tccccaagac catcaaaaaa cacatcattg ttgtaaaaat tattccttct
    39841 tttttatttg taggcaatct gtaccactcc tttaaatttg tcacgaaaat catcgtagca
    39901 catttaaaaa tttctcgtaa gtactttttt tattttctgc ccttttattt cataaacttc
    39961 atcagccgta cgctcgacaa agtaagaatc atgagaagta aacaaaatcg ttcccggata
    40021 tatttgcatt agcttctcta aagcttcgat cgttgccata tcaataaaat tagtcggttc
    40081 atctaacagc aacacattac ttggcttagt aaaaagcaaa gcaatcgtca gacgggtcgc
    40141 ttctccccca cttaatgtac ataacggttt cgtcaaagtt tcctgagcaa accctaagtg
    40201 attcagcaaa ctacggacaa gcgattctga aaactctgtt tgtctcatga caaaacgaat
    40261 gatggattct tcagatgtca tttgataacc cttttgctga tatacttgaa agcttacttt
    40321 cggagagaga aggattcctt ctccttgttt gcggatatgt tctaataagg ttgtcttacc
    40381 tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa gaaaactgaa aatcaccatt
    40441 taccagtaat gttctcccac ttctttccaa ttggacattt tgtcccatga tgggatagcg
    40501 gctgtggagt tcaagagatt ttggtactgg aaaacggatt tgtttcatct gctgcggctt
    40561 ggttgtttct cctatttttt ggagtcttct ctctaatgtt ttcgcattct tttggatggc
    40621 tttttgtaca ctgtcttttt gtttagagga agacaaccga tccagtctga tttgttgctt
    40681 tttcttttta ctggacactt tttccaactt ttccgcttgt tttttctttt cttggatcga
    40741 tttttccaat cgttttttct ctttcatgat cgactctgct tctcgtagct gagtcttttt
    40801 ctccaattcc ttttgagtga gataggcact ataattcccc gaaaactctc ggatttctcc
    40861 gtcttttact tcccagattt tcgatgctag ctcatctaga aaatagcgat catgactaac
    40921 aaaaaccagc gtaccataat aataacgaag ctcttcaatc agtcgatcaa tactttttct
    40981 atctagatgg gttgttggct cgtctagaag catcccttgt tcataagaag aaagaagacg
    41041 tatcaactcg atctttcgtt cttcccctcc gctccatttc cgctctgaag tttcttccag
    41101 tcttaactgg aaatgactgg ctaattccaa atttaggtcc tttgcttcag cgagataggt
    41161 taattgaggc aggtagttga aggtgatctc tgtttggatt ttcccatgat cgggaaaaag
    41221 ttcaccggct attagtttga gcaaagtcga tttaccgaca ccattttctc ctatgatccc
    41281 tatacgatct tgctgataga cacgaagaga atcaatagat agttctagct ggttgccaaa
    41341 gctgacttgt agatttgtta tatttactgc taaattttcc atatgtttta cactcctatt
    41401 tcatgtaaaa caacaattat cgatactaaa aaagagcaga aaaatctgtt tgcaaaaaaa
    41461 ctgcatcaca tcttttccta ctctgaacga aataactatg actaaatcac caaatctgtc
    41521 atagctttca cctattctac tgtcgttcga aaaaatggac atactccatc catgaaattg
    41581 ttgtttatac atgtcttttg aatttattta gttgttattc aaaagttcga aacgtaattt
    41641 catcgatgca gtcatttttc cgacctcctt ttttattagg ttaccacaca cgattcaaaa
    41701 aaagcaatag ctactgaata gtaactgaaa accttttatt cgaacatagt gatcttttct
    41761 ggtgctaaac gaacagactc gtaaccttct tctaccgctt ttcctattga taaaataata
    41821 actggaacat aacggtcttt atccaaacca aatgcctctg ccaactgatc tgcttcgaat
    41881 ccaccaattg gatttgtttc atagccatga tcacgcgcaa ctaacatgaa ttgcatagcc
    41941 gctaagctag aatcgacttt gactacatcg ttcatttctt ctcttgaaaa actcttgtaa
    42001 taaggaatga tcgcagctaa ttgttgatct ctgacttctt ttggcatctt ccctgattcg
    42061 taagcttggt tgtagatttc ttcgccatat tcgtaacatt gcatatcgcc aaaaatcatg
    42121 accattgcag aagaagtatc attttgtctc gtattgaaac ggatcaaagg acgcaagatt
    42181 tcttttgctt cctcgctttc agcgaccaca aagcgccatg gtttcatatt gacagaagaa
    42241 ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt cgtgtgggat tttgtatgtt
    42301 tcatcatata cgcgaacgga tcttctacca gtcataattg ttgaaaaatc atttttttgt
    42361 tccattatta ttaacctctt tcgtttctgt tgttatattg caaagttggg tattcaattt
    42421 atctaaaagt gttagaaatt gtttcatttc tacatcgctg aaagccgggg atagcacgga
    42481 acctgtatct ttatggtcca tttcacaatg cttgattttc ttctgggctt tttctgttag
    42541 cgctacatac acttcccggt tgttctgagg atttctctga cgcgaaacat agccatttgc
    42601 ttccaatacc ttcagatgac gagtaactgc tccttgatca atctgcaact tttcttgcaa
    42661 actgctttgt agcaatggat tttcttcttt cagtctcatc atgatctcgt atctagtaag
    42721 acttataccg atattttctt caaagatctg gacgattttt tgatcggcta atttgatttg
    42781 atataaaagg tgactaatct cttctaaaga cataatttcc tcctttctaa taattgactc
    42841 gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa aaagtcaaag aatcagctgt
    42901 gtaataaaaa aaacgctctc aatagaaaag tatagagaaa agaaattttt tgtagaatga
    42961 acggaaaaaa tgataaagaa agcacaacgc taaaaccaag attattgatt cttatcaaac
    43021 tatagaagat agctcttctg cagtagataa ttttacaccg ccaaaaattt ccgaaatcgc
    43081 cttttgcaag aatcccgtcg aatattagaa attggatcag tatgcttaaa cagtaataaa
    43141 aaagttatga caagatgttg tcacaacctt ttttgagtaa acggtgttca aaaacttgca
    43201 tctgcggtaa taagttcaac caaacaaaaa acatgaaaat ctgtttttgt ttggctgttc
    43261 ttactacttg atgcagggca gctttttcac tacctctttt taataaccat aaaatcctat
    43321 tccttcatat ctccagccca tcggtgttag ccaatctctt tccttagcac tcaaggtata
    43381 gtgatgggta ccagtttttt catttggatt aaatagtcga taaattggct tggaaccacc
    43441 agaataaaaa cttagacctt cataacgcca accgattttt gttaaagagt tgatctcaga
    43501 ttgtgccatt gtgtaatgat ggtctccact gtaaggattg tataaacggt agacaggttg
    43561 tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc cagcctacag ttggcagata
    43621 atttttttct ccggcattca atgtatataa atgttctcct gtatgacggt tatacagacg
    43681 atacatcgga gaagttgaag ttggtgctgt atcatactgt gtcagattat aggtttcgat
    43741 tacattgttc aatgtagaac cataattagg cgcagtggca taacgacctg ttagccaagc
    43801 cgtagcatct ttgtaagagt tcgtattgct tttccatgca ccggaatagt agtaaacgcc
    43861 tggctgaaaa gaagtcgtct tcaataccgt tacgttatct tgcaatgatt ctttgtacga
    43921 aggatatttt ctaaaagcgg cattcaccgt aatccattgc ccattcacat attccgaagt
    43981 aggcatcgta acagattggc cattatagct tcctttaatc ccaaatagat tgtaattagg
    44041 ggcagaagcc aaagtactgt tcccccagcc actttcaacg atggcttgag caatcatgac
    44101 tgatgcatat aagtcattgg cacttgccaa actttgtgca gttgaggcaa tactatcaat
    44161 gaacgcttgt tgagaattag cagatgagcg agcataaaaa gcatagccag tatagttttc
    44221 gaattcagac aaatctgctt gatgggtatg tgtcaatgtt tgcccatctg tcaattggtt
    44281 cgtgatttct tctgcattct ctggattgtt ctgagcttct gctgatgtac tgtcttcggt
    44341 ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt gaaattgtat tttctgagac
    44401 agtagctgac tgcaaagtac tttctgtatc gttttcaatt cctgtttctg aagaactcga
    44461 tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc actgttgtgt tggcaactgc
    44521 tagatttcct aaaagaataa cgctaaataa taaattcttt gctttcatct tttttctcct
    44581 ttgaattatg aaacttttcc taaataacag tgtaactaaa aaagtaaaag caagtcaatg
    44641 tccatattta aataacattt gtttcttttt aataaatttg ctttttctgc ataaaaagac
    44701 gtaaatgaag aatattcttc tccattcacg ccttaaattg atggtcgttt gaataactat
    44761 ttaacaagta attctctctg gatattatcc gttatggatt atacttcctg tgtcgtcgga
    44821 cggataatca tgttgctgac agacatccgg tctggcgttt ctatcgcaaa tgctacagca
    44881 gaagctatat cttcagatgt taatccccat tctttttgcg cttcatgaag ttcaagagca
    44941 gcctttttgt cgctgatggt ttgatataat tcagtttgaa cagctcctgg agagatgatc
    45001 gtagatttga tgttattttg ccgttgctct tgacgtaatc cttccatgat tgcacggaca
    45061 gcaaattttg ttccgcaata aacggcggaa tcaggataaa caacatgtcc cgccacagaa
    45121 tcagttgaaa tgatatgccc agatttttgt ttttccatga ttggaagtac ggcggaaatt
    45181 ccatttaaca cacccatgat gttgatatca agcatatttt gccattcatc acggtgacct
    45241 tcaactaatg gagcggttgg catgattcct gcattattgt acaatacatc gattcgaccg
    45301 aacttttcca tcgctaaatc gataactgct tggacttgtg caaaatctct tacatctgct
    45361 gtttgaatat atagctcagc ttctggtaaa gattctttta ttgcttttag gcgatcttct
    45421 cggcgtgcag ctataactag tttagcccct ttttctgcta atagcttcgt tgttgcttca
    45481 ccgattccgc ttgaagcgcc catgatgaca atcacttttt ctgataaatc attcattcta
    45541 ttctcctcct gttttgaaaa atctcttgct tatactcact atctcttatt tcatcttact
    45601 gttcaaataa tccgttcgac aggtttgacg attttggcag ggattcctgc aacgatggta
    45661 ttgtctggga catctttcgt aacagttgca ttcgctgcaa caatggcatt ctcgccaatc
    45721 gttacgcctg gcagaatagt tgctcctgct ccgatccaag catttttctt gatgtggatt
    45781 ggctttactg acaagcctct tcgttctttt ggatcggtta gatggttcac cgtgatgagg
    45841 ttgacacgag gaccaatcaa tactgaatct tctaaacaga tgccacctaa gtcaacgaac
    45901 atcacttgac gattgataaa gacatttttc cctatactaa tatgtttgcc gaaatctgta
    45961 taaaaaggca gcagaacagt caccgtatca tctactttgt cactaatgat attttctagc
    46021 cgtttgcgga tatctgctgg ttcatggtac ccagtattca gcgctgctaa aggctcttcg
    46081 ttttccgctt ggatctgatg gatcacttca aagagcggat ccgttactcg aatctcttta
    46141 ttgacgattt gtttttcgat gaggcttgtc attttgctcc ctccttttat ccttacttta
    46201 taacggacgg cttatgatgt ctaatactta taaaacatac ttaactattc cttttaacta
    46261 tacttagtgg tatgcttttt taaaaacagg agggaaaaaa tggatattcg tatactgacg
    46321 tattttttag cagtagctag agaaaaaaat atcagccgag cagcaaaatc tctgcatatc
    46381 acgcaaccta ctctctcaaa acaactgaaa gatttagaag aagaacttgg tgtgacactt
    46441 ttcactcgag gctcccgaga gatacagttg acggattctg gtcgatatct ttattcaaaa
    46501 ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc
    46561 atctctggag aaatctacat tggcggaggc gaaactaaag caatctcttt catttctgat
    46621 agccttcatt cgttgatcaa ggcgcatcct gatatccagt ttcatttata tagcgggaat
    46681 gcagatgata tcatagacaa actggatagc ggattacttg attttggact cgtaatcgaa
    46741 ccgacaaaca aacaaaaata ccagtcattt cgactgccag cccaagatcg ttggggactt
    46801 ttgatacatc ggaatcatcc tttagcaaag caaacagtca tccatccgca ggaactgaaa
    46861 actgttcctt tgatcatttc ccggcaaacg tcagtggaca gtcaactagc tgaatggcta
    46921 ggtttcagca tagatcagtt atcgatcgtc ggaacatata acttattgta caatgcttct
    46981 ttgatggtcg ataacgggac ttttggtgca ttagctctag atgggatcat caatacttat
    47041 gggacggaaa aagtattcat cccactcgat ccgccattac aagcttcact gaatctcatt
    47101 tggaaaaaag accagcctct ttctcctgct gctcgtaaat ttttagatgt cctaacggag
    47161 aaatacagtt aagtagagtt tttttccttc gctttcagct ttttaacaac gaataagtta
    47221 agcaaaagat ccaatgatta aataacataa gtttcttaat ttgttccttc cttttatttc
    47281 tgataattcc agtaaattac tataattata aaaaaagaat tgacaaaaca taactgtcta
    47341 tataaaattg attacgttaa caataattcg tttcatgtga ctagatcata ctaggcatga
    47401 aaaatctctg aggaacatgg tttccctagg aggtttttcg tgtctatttt tgtttggccg
    47461 caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa aaagggtgcg cgcatgaaaa
    47521 tcaaaaagat ctttaatcaa aatgcagtat tggtagatga cggtggacag gaaaaagtag
    47581 ctattggaaa agggattgga tttgacagaa aaagaaatga tttgattttt gatcgtgatg
    47641 tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa gttgcaaaat ttacttaatc
    47701 agattgatga acgcttttta tttgcagcag aaacgatcat tgatcatgcg gaaactgttt
    47761 tgatggaaaa gttgaatgaa catgtattga tcgctttgac cgaccacatt gctttttctg
    47821 cggagaacat taataacggt atcgtcatcc gcaacaaact tttaagagaa atcgaagtgc
    47881 tttacagtga tgaattcagt attgctcaat gggcagtaga gtatctgaca aaagagcttg
    47941 ggattccata tacttatgac gaagcaggat atatcgcaat ccatattcac agcggacgaa
    48001 gcggtcggaa caataaccat cgcagtatcc gtgaagtgac gattgtatct gacatcatcc
    48061 atttagtgga atcagaattg gaaacagata tccattcaga accattttca ctgaattatt
    48121 caagactggt gaatcattta cgactgcttc tacaacgaac ccatgcgcaa caatatgctg
    48181 ttttagacac ggaaatcgta gaaatggtca aacgaaaata cccagaaagc tataagattt
    48241 ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct cgcgatcacg aaagaagaac
    48301 tgggttactt ggccatccat atcgagcgtt taagaagcgc aatcgtacaa acaaatgtta
    48361 acaatcatga ggaggaaaaa aattgaaagc atatctacaa cgaatgggac gttcccttca
    48421 acttccagtt gcggtcttac ctgctgctgc tttactagta gggatcggaa actggtgggc
    48481 atcttatagt aacgacattg tcgctcattt tttacaagct ggcggtaacg cagttttagg
    48541 tcaattacct ttgctgtttg ccgttgggtt agcactaggg atgtcagtgg acaaatcagg
    48601 tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca gtaaatgttt taaaaactga
    48661 ttcagtagct actttattga atatcaaacc agaatcagtt gatccatctt ttgctcagat
    48721 cagtaacgta tttattggta ttattgccgg attgattgcg gcagctcttt ataatcgttt
    48781 ccacgaagca aaattaccga tggctttatc tttctttagc ggcaagcgtc tagtgccaat
    48841 cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta ctgctcgtat ggcctccggt
    48901 ttactctgct ttagtttctt ttgctaaatt cattttgagt ttaggctggg gtggtgcagg
    48961 tctttatggc ttcttcaacc gtttactgat ccctacagga ttgcatcaag caatgaactc
    49021 cgtgttctgg tttgacgtag caggaatcaa tgatattggt aaatttttgg cttctgaagg
    49081 aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc ccaatcatga tgttcgggct
    49141 tccagcagga gcatatgcta tttacagaaa tgcacgtcca gaaaacaaag caaaaacagc
    49201 ttccttgatg ttagcagcag cttttgcttc attctttact ggtgtaacag aaccacttga
    49261 attctcattt atgttcgttg cttggccatt atatgtcttg catgcaattt tcactgggat
    49321 ttctttagca gtgagtgcat tcttccattg gacagcagga tttgccttta gtgccggatt
    49381 tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat cagccattga tgttgatcgt
    49441 ccaaggatta gtaacagcag tgatttacta ctttggcttt aactttgcta tcaaaaaatt
    49501 ccatctgatg actcctggcc gcgaggaagc agatctttca gatgacgata ctgcaacgac
    49561 taattcagac aataaatatg cggcacaagc aagcaaaatc tacgctgcat taggcggagc
    49621 cgacaatgta acttctatcg ataactgtac tacacgcctt cgtttgcaag tcaaagatac
    49681 aggcctgatc gatcaaaata aaatcaaagc cactggcgta cctggtatga agatcatcga
    49741 cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa ttcgttgcag atgagatggc
    49801 aaaactacat ggtggtgctg caacacgacc tgcacaaaca aacaccgtgg ttaaaacaga
    49861 aacatttgcc ggtggaacga tcgaacaaga tatttacgct atcgcaaatg ggaaactgat
    49921 tccaatcact gaagtttcag atgatgtatt cgcggaaaaa atgatgggtg acggctatgc
    49981 tgtattacca gaaaatggag aaatcttctc tccaatcgct ggtacgatca caaacatttt
    50041 cccaacgaaa catgctgtcg gaatccaaac agatgctggt atcgaagtct tgcttcatat
    50101 gggcatcaac actgttgact taaaaggcga accattcact ttatatgtaa aagaaggtca
    50161 aaaagtcgca agaggtcaat tgattgcttt agttgatctt gccgctattc aatctgcagg
    50221 caaaaacacg gatatggtcg ttgtattcac aaatggcgac aaagtccaaa gcttagaaat
    50281 cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc tctgtttcca acaaagcctg
    50341 agccatcgtc ttccccagac ttttttatcg ataaacaaac aggagctgag acaaaaatct
    50401 tgtctcagct cctttttccg aataaaaacg gcgttctcct gccaactccg cggtaataag
    50461 tccagccaaa cgtaacatat gaagagctat tttttatttg actcttctta ttacttgatg
    50521 cagaacagct tttttacaac ctctgataaa cggtgttcaa aaaccagttt atcggtatga
    50581 agtcaaattt atgcaaaaat gtggaaagcc attttcacaa aatttttctt catactcaaa
    50641 actaatcggc tttttcacaa cctctttata cattattcct gatccaatat ttcttttaat
    50701 gctgcttcaa gagaagttaa tggttttccc aatacttttt ctaaatcatc agaggaaata
    50761 gctaactgat cctttttaat atcatgttgg atcgctaaaa acatgtcagc tgcttcttga
    50821 gggaatccgg cttcttttag attttcgaca aacgctgcat cacttgcttc aataatttct
    50881 aactttttac ctgtcgcacg ctctaatgcc ttggctaatt cttcatagtc agttagattg
    50941 ccggataatt ctaagatttc tggagagtca ctttctacta gtacttttgc tgcagcttct
    51001 gcatattcac gtttcaatgc ccaacctgtt tttccatttc ctgcagcata aacgaattga
    51061 ccagttttta aagcctgccc aatgataggt aattcattct ctacatacca attattccgt
    51121 aaaaatgtat gggaaatacc tgaatcctta atcatttttt cagtgaattg gtgatctggc
    51181 gctaatacac tgatcgagtg atcggcatct gcaaaacttg tataagcgat ataagatacc
    51241 ccagctgctt gtgctgcctt cactacattc ttatgttcgg cttgacgatt tcctggaacg
    51301 ccagagacaa aaagcaatcg atctattcct ttcaacgctt ctttcattga gtctaaatca
    51361 tcataatcac caatacgtat attaaatcca gcttctttca gtgcttctcc tttttcttca
    51421 ctacgtacta gtacatagat ttcattttgt ggaaccatct tttttaagaa ttccagcgca
    51481 taaccaccaa aacctccagt tgctcctgtt actaaataat gcatatttgc cactccctat
    51541 tctttttatt tgttaagatt tacagctgta catttataaa ttacaccttt atcataaaga
    51601 gtgtggtaag ataagtcaag caaaaaaaat gaaaggatga caactgatga agtattctct
    51661 gcaatttagt gatgcaatcc atgtacttgc ctatattgaa atgtttcaag atacccgatc
    51721 actttctagt gagatgattg ccagtagtat cgaaacaaat gcagcaaatg tacgtaaaat
    51781 catgagtcag ctcaaaaaat ccggtttgat ctttacaaaa accggaaaac cgcagccttc
    51841 ccttgccaaa agtccagatc agatttcttt actagatgtc tatcgcagca tcgaaggtaa
    51901 tacacagctt atccaagtcg atccaaaaac aaatccaaat tgcgtcgttg gtgcgaatat
    51961 ccaagaagct ttagaagaaa gctacgctcg gctgcagaaa aaggcagaag aagaaatggc
    52021 taagatcaca cttgatagtc tgatacataa aatagccgtt ttggaaaaag aaaaaagacc
    52081 agaaaacaca ggcctcgtag agagattttt ataattctct ctactgtgcc tgcatttttc
    52141 tgatcggaat cgtctacata aattctttta ttctccgggg gacaaaagcc ttgtcatgcc
    52201 cctttttcct ctctaatgct caggtcaaag cgctgaagtc atgacgtctt gataaacggt
    52261 gttcaagtag ctgaccctcg gcattagttc tgaaaaatgc aaaatatgga aagctatttc
    52321 ccatttttcc tctctaatgc tcaggtcaaa gcgctacttt cacgacctct atattatcat
    52381 ggtttattga ctaccggtat ccagatttct cccatatatt tcccgttggt aactcccatt
    52441 tcgactacag catttggacc cccaacatag gcgtaatctt ctacttctct taaaacatgc
    52501 ccaaaggccg tattcgtcaa atcatttctt aattcttcag gcgattctgc taaagcgatt
    52561 acaacaagat acgttccttt tgggaatggg atgattcggg tagtgtttgg aacatcctga
    52621 ctcgtttgaa caccgacata gtacatcatt ttcccgttat agggttcgtt gactgtaaag
    52681 aaataatgat tttcagcagc ttgtttcaat gcatctattg ttccattacc gataactttt
    52741 tgctcaaatg cttgtttctc tgcagccaaa ccgacaaaat ccgtattgct actcttcaat
    52801 tccacaccaa tacccgtcac cgtaaaatct ggtttttctt cgatcctata ctttgccatt
    52861 tctcccaccc tttctattat attaagttca tcttacataa aattaaaggg aaatgacacg
    52921 attacgctct tttttctagg gatattttta ttttttaact atttttttgc tttcactgca
    52981 atccaaatct cactgtaaac attactgaaa tcctctcccc attttgtaaa agagatctcg
    53041 ggagcttcga ctaactcata atctgaagaa ggaagccatt ctgcatagat tttcccccaa
    53101 gtatcttgta aagtttgggg aaatggccct ttattaggaa aaatggccca agtgtgttct
    53161 tctatagcaa gcatttctaa atcagcgtac ggattttctt ttgtcgtagc aaagccaatc
    53221 atgtgcatca aactgccctt ttcttccaag cgggctccat caaatccata agaaacgttg
    53281 attacttgat ttggatataa atctcctaac ttatgcatct cttccctttg agtctccgtg
    53341 atcgtctgcg ctaacttttg tatttcttga ttgactcctt caaatttgac aggaactttt
    53401 ttcgccacac ctgccacata aaactgttct ttcttttcga tacgaaattc catcgatttt
    53461 cctcctctga catcaataaa aaatgtcaag cgtggaaaag atttttgtat gccgtatctg
    53521 ctgatttctg aaggcagata tcctgaccaa tcacgaaaag ctcttgaaaa accttcgact
    53581 gtttcatatc catatctaaa cgccgtttct gtcactcttg atccatctag gagatcgcga
    53641 ttagccaaag ccaatctacg gtttttgata tagtccatta gcgacatccc tgcaataaac
    53701 gtaaagatgc gttttaattg atattcagag attcctgtat tttcggctat tattttatag
    53761 gaaagtcctt ctgtcaaatg ttcttcgatg taatcgatca attggttcag atctttaagc
    53821 atatttatct tcctccttgc ttgccttttt atcatattat caaagaaagt caattacttg
    53881 atgaatcagg aaccaattta gtcagatgta gaaaatgttg tatggatcta aagaaaattc
    53941 tcaagcagcg tttcgtaacg gataattggt attatctgcc tatctatgtt ttacctttag
    54001 aaaaataaat tttggggaag acacattcta agtaaacaaa gcggtaaaaa tatcttttat
    54061 tcccttagtt aatccgctta ctacctactg tacaaagcaa attgttgttc aaactgctga
    54121 tcagaacgct gcttggattt ttctttgcga tacatcatac ctcttttatc aattggaaca
    54181 attatttatt tctaacaaaa tcacttcatt tttgtcagat aaataaaaaa caaaaaaagt
    54241 tccatcttta aaacacgcta ttcttttact ttttctcaca ttctctaaga aaagaaaagg
    54301 agaatgaatt tttgacaatt cgagcaaaag tgattatcaa atatgtaaaa tcagctactt
    54361 ttttcttaaa cgtttcttta tactaaatat aaataagtgt ttcatgaaag gagaactaga
    54421 tgaataattg gcttgagtat tttcctgaaa acgttttgga acgcggttac agctatcatc
    54481 tgcacggttt tgtccgtcat ttgaactata caagcaagta cttgtccgca acagtttctg
    54541 gcacggaaga ttataaggta gtgatcactt gggatgaaaa gaccaacatg acttgtgatt
    54601 gtctatatgc catagaagga aaaaaatgca aacacatggc tgctgtctta ttcgcttacg
    54661 aagaacgtcc aataaaaaaa tccaactact cactttccga actctcgtcc cttgtttcct
    54721 ccgctagttc ctctcttgta cgggagcttt taacagagat tcttatagaa catccgcaat
    54781 ttatcgaacg cttcaaagtt aagatgccat ttcatgcaat aaattattca gataaattaa
    54841 caactatcat ccataaatac gatcatatta tcaagaaaaa caaaaacagg aaaacagcga
    54901 agttcatcat ggagatgcga aagttcatcc aagaagcagt tgaatcgctc attcagcaaa
    54961 atgcctatct tcccgcattc gaattgatca atgaagtgat tgctactctc gaaacattct
    55021 attgggagcc tgaggatgaa cgaacccttc ttctgataga ggactgttat tatttatgga
    55081 aagaattatt agcagaagca cctcatgcag aaaaaaggca aatgttctct tggttcgtct
    55141 gccaagtcga tcatactgac gcctcttatt caaaacgcta ctccataaaa atcctgaaag
    55201 aagactttcg ggaaaaagaa ttttctaacc aaaagaaaaa aatagataaa aaaactaaag
    55261 aaacggtaaa gaaagacgat ttcaatgaaa aatagcaagt aaacgataac aaccatccta
    55321 aatccacaag aaatacagca gaccttgctt taaaaacacg aatcatgcaa aggatgaagt
    55381 aaagaagact taacgcgtac ccaatattag tcatttgact attaggtacg cgttttgttt
    55441 tataagtcat gacaaatttc cttcgttgct gggtagattt tccggcattg ttgatagatt
    55501 ttatgatact tttctacatt ttgtaagaga ggttccactg catctgtata ttggataaaa
    55561 ttctgacaac aactttcagg tgtgtcgaac cactctaatc tttaaagata aatattaaaa
    55621 taacgattaa taatattaac agtctttatt tttcaccacc aaaaacctat ctttgcatat
    55681 actaaataga cgtatataca cagataggtt tgtcttgtga aaaataatga ttatccttac
    55741 caaaaaatgt ttgtttttct acatgttcgt acttatcaaa aaatatgatc cttattgaaa
    55801 ttactggcta tttatattcc aacgacttct tgtgttaatt tttgttatct catagtaaat
    55861 tatgtttcat tttcacttaa tttagttgtc acgtgttcgt caattcgtaa aaacggtaaa
    55921 tatataaaca cacttgcggc tataattaat atttgtaaaa cagctgctcg ccagtctccg
    55981 gctgttgcta aaaatcccga tataactggt ggcgtagtcc aaggaatttg cactactaca
    56041 tgattaatta atcccacagc agttgcaaaa tatgctactg tcaaagaaaa aatcggtgca
    56101 agcacaaagg gaataatcag actgatatta aatacaatag gcaatccaaa aataataggt
    56161 tcgcttatat tgaatatagc gggagttacc gataatttag caaagtcctt ataatctttt
    56221 ctacgactga agataaatat tgcaatcaat aaagcaatcg tatttcccga tccacccatt
    56281 accgcaaagg tatctttaaa ggccatattg ataatatgtg gaatttgctc tttgtttgca
    56341 taagctgcca tattttcttg catattctga atcaaaaacg gatctaacaa tgaacctgat
    56401 attactgctt gatggatacc aaatccaaaa aatagattag caatagatgt aattaacaaa
    56461 aatcctggta aaccagttgt aattttactt aatggctctg taactatcgt ggtaattagc
    56521 ttatttatat ccatattaaa caattgaatg attataaatg acaataaagc aaacgaggta
    56581 atcgtaataa tgattgggat taatacatta aaagacttta aaacagcggg aggaatattt
    56641 ccggatagct gaatctgtag tttcttatta ttagaaagtt taataaataa ttctgtagcc
    56701 gctaatccaa caaatatacc tacaaacatt cctgaagctc ctgtatagga tataggtatc
    56761 acacccgtca cttcaacagc tttatccgca ttttcaggag taaacatcat ctgcataggt
    56821 gttaatacaa caaatgtcga aatagcaact aataccgctg caatatgatt tgtataattt
    56881 ctgcttgcac acatatgata agatactgct gctacaacta ataatgtagt tatgcttaat
    56941 gtaccattgg caattgaagt accaatttgt tgtaacgtgg tcaatgtact agtatcgaca
    57001 atttccccca tgaatcctgt tggttctaag atcactgaat taataagtgt cacaaatcct
    57061 gctaacatca taaatggcat aaatgtagca aacgcatctc gcaaagttct taaatggatc
    57121 tgattcccca acttagtcgc aactatacca aatttttcaa atacaatgtc cttcctgcta
    57181 cttttgccca tattttttct cctttatgct tattgtaatc gattactttt tccacccaaa
    57241 taatacatca cttatcaaaa aaagtaaata cttttaatta aatatatata tcttttttag
    57301 tataaaaaaa taagctctga aaaaataatt ttcccgagct tatttttcaa caaaaacagc
    57361 ttcaaaaaca aagtcttgat ataaatgtct cgataccgaa tactcgaaag gtttaccaga
    57421 cgatagagca acaactttgt ctatctcaat cataaattca cctggatcta tttttaatat
    57481 ttttgcgtca aattcattcg cagtatctcc tttgatacgt atgtgcgaag tctttatttc
    57541 cagacccagt tcatttgtga tataagcata tacagatttc tttaaatgtt ttggttccaa
    57601 gcctggtatg actgctaatg gcatgaatgt ttgctcaatc gagtatggtt gacaatcaat
    57661 aaaacggctt cgtacaatat tatatacata gtcttttaca ctgatactta atttatcagc
    57721 tacttttttc gatggaagtt caattgagaa agtatggatt tctgaatcta cgtgttcttc
    57781 accaaccacg ctaaacaaac cttcgtttgg accaagaact cgtgagttat caattggtgt
    57841 tctgacgact tcagtcccat acccacttct acttcgcaaa actccttcgg aaacaagtaa
    57901 gtctacgcct ttctttactg ttaacttgct tgtatgataa ataactgcca attcatctcc
    57961 tgtaggaagt ttctcaccaa ttttatactc tccatttaca atttttttct ttatatctaa
    58021 gtaaatttcc atatacttcg caattttttt caatggtgac cctccaatca aaaacatatc
    58081 ttcatctata ctttaacata aataaaccga taaaatccac atcaaaatta tacacacaat
    58141 aaaaaagata tatatattta aacaaaacta tttactttaa gttgtaagcg gtgttatcat
    58201 taagtggaaa caggaggtaa aaaaattatg acaactatga aaaagctaac ttttccagat
    58261 gatttttggt ggggttccgc ttggtcagct gagcaagcag aaggaaaagg agaaacagga
    58321 aaagcagaga ctatctggga tcgctggttt aaagaacaac cttaccggtt ttatcaacga
    58381 atcgattcct ctattacaac cgatcacatc catcaatata aagaagatat agaactaatg
    58441 aaaaaaactg ggcataactc ctttcgcgtt tctatttctt gggcacgaat gtttccaaat
    58501 ggcggtaccg gaaaagtaaa tcccaaagcc atttctttct atcgaaaatt attttccgaa
    58561 atgaataata acggaatcaa agtatttgcc aacttatatc attttgacat gcctgctact
    58621 cttcaagata aaggaggatg ggaatcacgt gaagtagttg atgcttatgt tcattacgct
    58681 gaaacttgtt ttaaagaatt tggtgactta gtttgtcatt ggtttacctt caatgaacca
    58741 cttgggccta ttttaggtac ttatcttgaa gattttcatt atccaaacct cattgacttt
    58801 aaacgcggag cgcaagcagc attcttcact atacttgcac acgcaaaagc aatacaagta
    58861 tttaaagaac tagctcttcc tagtaaaata ggcgttattc taaatttgag tcctactttt
    58921 cctcgtagtc aaaatcctgc tgatgtgaaa gcagcagaaa tcgctgattt attttatacg
    58981 cggagctttt tagatcctat ggttaaaggg aatttttcta aaaagcttat cctgttatta
    59041 caagaatata atcagcttcc tgaagattat acgaaagaag atcttgtatg tatctacgaa
    59101 aataccgctc aaattcttgg actaaactat tacgagccac gtcgcgtcaa atctcgttct
    59161 tctatggtgg atacatctag tccattttta ccagagtggt ttttcgaacc acatatcatg
    59221 cctggacgac gaatgaacga ataccgggga tgggaaattt acgaaaaagg aatttatgat
    59281 ttgtgcatgg atatcaagaa ccattatgga aacatcgaag catttatctc ggagaacgga
    59341 atgggcgttg cggatgaaga acgtttcatg gatgatacag ggcaaataat tgatgattat
    59401 cggattgagt atatcaaaga tcatcttgct tacttatgga aggcaataaa tgaaggatgt
    59461 aacattaagg ggtatcatct ttggacattt attgattgct ggtcatggat caacgcctat
    59521 aaaaaccgat atgggctggt ttcactcgac cttactactc aaaaaagaac aattaaaaaa
    59581 agtggcgaat tttacaagca attaagtgat acaaatggat ttagatacga tgtagacttg
    59641 ttagttgaat aatattctaa aattccactt gaagtgaaca cattagaaaa caagaataat
    59701 gagaaatacc aataacaaat actttttctt catacttcat ttatacttgt cagtataaga
    59761 gactgtgaca aatgtagtga tcctcagaag ttaggtctgg aaatctaact tgagaagatt
    59821 tttttaaact acgtccagtc ttttttattt gtttaaaatt gaagttgaca agtcttcatt
    59881 aaaaatttag aatattcaca agtttgacga caattatgaa aatttatgtc gtgctaaagg
    59941 agttttgtta ttggatgaaa agttagatat aaaaactgcg atcaaagaca cgttacctac
    60001 cgtttttggt tatatcggta ttggacttgc atttggtatc gttgggaaag ctgccgggtt
    60061 tcatccgctg gtcgtcacgt tgatgtccct gctgatctat gctggttctg cccaatttat
    60121 cacggtcagc atgcttgcta gccatagtcc actgctctcc atcgttctct cgacctttct
    60181 agtcaattcc cgaatgattc tgatgagtat gacgattgct ccttatttca agaaaaatcg
    60241 gctgcttcaa aatctgctga ttggcacatt gctgacagat gaaagtttcg cactgggaat
    60301 gaataaattg aactatactg gacaaaagtt aaactttcgt tggatgaata cagctaattg
    60361 gatttcttat ttgacgtggg tgggttcttc tcttgttggc gcacttttag ggaattttat
    60421 tactgatccg aaaaagtttg gtttggattt cgccatcgtc gctatgttta tcgggttact
    60481 ttatcttcaa gtcatttctg atagaaacac ctctaaacga ttacagttga tcctgattgg
    60541 tctcactttg attctggtat atgtcggact gatttttatc ccaagtaact tagtgatttt
    60601 agttgtaaca ctgattgggt gcggattggg ggtgtggatc aaacatgcct tcttttgagt
    60661 ttacattgct gactatttta ggttgtactt tagcaacttg gctttctagg atcctaccat
    60721 ttgtcttact gaaaaaattc gatttgccgc aaccgttgct tgagtattta agttttgtcc
    60781 cgatcgtcat tatgtctgct ttatggttca gcagtctatt tacccaaaat atcggacatc
    60841 tgccgcagat caatctcgaa aatgctttgg cttcagttcc tacactttta gctgctattc
    60901 tttcaaaaag cttattggtg atcgtcttgg taggaattct ttccctttcg ttgattcgct
    60961 tattataaat aaaaaaacaa gagcttatgg caaattactg tcatgcgctc ttgtttttat
    61021 caaagtcaaa taagaaaaaa atcggcgtat tcttgcttat ccgttgaacg gaccactaac
    61081 aacgactttt cctaatatat gtcctgtttc tacgtctttg gttgcttgtt tcaagttctt
    61141 cgcattcatc ccatctgaat agaccttgct caatgtactg cggataatcc cttcatttgc
    61201 taaagcagca atgtgcgcta aagcttctcc ttgcgtttcg atttcatagt tatagtctgt
    61261 tttagcgaac atatactccc agtcgaagct gatagattgg tttttccaaa cacctatatc
    61321 taacggctct ttgatcccta cgatcgttcc cacatgtcca aatggtcgga caaggtgttt
    61381 gatttgatca aagtagcggg taatatcgaa taatacagcg acatactcta cttgatcgat
    61441 tcctaattca cgaaaacttt tacttaagtc gtgatgataa tcgattggat agtctacacc
    61501 tgtttttttc agccattcaa aattcttcgg acttgcagtc gcgtagactt ctaggccagc
    61561 ccaatgcgct agttgattca aaatcgaacc gacgccccca gctccgttga tcactaagat
    61621 ttttttcccg cggttggcat tttcttctgg agtcagacca aatttttcaa ataacaattc
    61681 ataagcggtc aatgaggtca acggcaaggc tgcggcttct tcatctgaaa gattttttgg
    61741 tgcaagagcg acaatacgtt cgtcaaccag ttggtattct tgattgcttc ctgctcttgt
    61801 cgttgtacct gcgtaaaaaa cgcgatcgcc gacagaaaat ttttgcactt catcacctac
    61861 agcaacaact ttcccgactc catcaaaccc taagatacgt aaagcatttc ttatcccgtt
    61921 atcttggcga agtttcgtat cgacaggatt aacagatact gcgttgactt ttaccagaag
    61981 atcccgtgaa ctgggtacag gtatctgttc tttttcatca ataaagcttt ttggatcatc
    62041 gatcgacaac ccttcataaa aaccgactac cttcattaat tccttttctg acatacgaat
    62101 tcctccttag cttcatcaag ttggagcatc catacagttt tcatttcaat atatatagta
    62161 tgctatttgt tccactttta ttcatcataa ttattctctt acttaaagta aactatttgc
    62221 acttttttgg ttaaaaaaga ggttgcgaca agacttttgt cacaacctct tttaaacggt
    62281 gttcaatcaa ctgaccctcg gtattcgctc aaaaaacgac aaaatatgag gagctatttt
    62341 tgtttggctg ttcttattac ttgatgcagg acagcttttt cacgacctct aattcacggt
    62401 gttcaagcaa gaaatcattg ttcactgaaa agcgttggat gttctttttc aaaggtgtct
    62461 aagatctctc gtacttcatc agtagatttc gtattcatca actgaactcg caagtcattt
    62521 gctcctggaa atcctttgat atagatttta aagaaacgat gtagtcctgt gatggaacgc
    62581 gggatgattt ctgaataatg atcttgcaga tctagttgca gacgaagtag tccgatcagt
    62641 tctttttctg tatgttccct cggttctttt tcaaatgcat aaggattctt gaaaatcccc
    62701 cggccaatca tgatgccatc tacgccatat ttttcggcca attcttctcc tgtctggcga
    62761 tctgggatat ctccgttgat cgtgatcagt gtttgcggag cgatttggtc acgtaaagca
    62821 atgattttag ggatgacttc ccaatgtgca tctactttac tcatctcttt acgcgtacgc
    62881 aaatggacag aaagattggc tatatcttga tgaagtaggt gactgatcca ttcttccatc
    62941 tcagacattt ccgtatagcc gatacgcgtc ttgacgctga caggcaaacc gccagcttta
    63001 gccgcttcaa tcaattgtgc cgctacttct gggcgaagga tcaagccact gccttttcca
    63061 cgttctgcta cattagggac tgggcagccc atgttgatat cgattccttg gaagcccatt
    63121 tctgccatag caatgctcat ttctctaaaa aattctggct tgtctcccca aatatgggca
    63181 accatcggct gttcatcttc tgtaaaggtc aatcttcctc gtacactgtc ttttccatct
    63241 ggatgacaga aactgtctga gtttgtaaac tcagtaaaga agacatccgg tgctgctgca
    63301 tgctttacga catggcgaaa tacaacatct gttacatctt ccattggtgc taaaacaaaa
    63361 aaaggctttg gcagctcttt ccaaaaatta gtagtcattt atttgttact ctccattcta
    63421 tcaagcagtg aagtcgcaat ctttctcaaa aacattgtca ttatactagg aaacaaaaaa
    63481 agaagcaaag tgaacagctt aaaagatgtt tctgattgag caaaaaaaga ctgtgacaaa
    63541 aatcttatca caattccttt tccggaataa atggtgttca aaagcttgca tctgcggtaa
    63601 taagtccaac caaacgaaaa ataggaggag ctatttttgt ttggctgttc ttattacttg
    63661 atgcagaaca gctttttcac aacctctcca ctaaacggtg ttcaatcagc tgaccctcgg
    63721 tattagctca acaaacgaca aaatatgagg aactattttc ccgtttgttt ctctaatact
    63781 caggtcaaaa cgctgatttc acaacctctt ttctaacttc tcaatcctct tcctttattg
    63841 atcaaatacc aagtaacggc gtacaaaaca acgatgaata gcacaagtac gatcatcgat
    63901 gttgctactg gcacatcgat tgttccaagg aatccgtaac ggaaaccgaa gatcatataa
    63961 acgatcggat tgactttcga aacagcttgc caaaatggcg gcaacataga gatggcatag
    64021 aaaacgccac ctagataagt taacggctgc aagacaaatg taggcacgat cgatacatcg
    64081 tcataagact gagcaaaaat cccgttgagc agtcctgcta acgaaaacaa gattgccgtc
    64141 atcaataatg taatgatgac catgaaccat gaatacacat gaagtggtac aaagaacaag
    64201 gaaatgatcg ttacgagaga gccgacgaga atactgcgac ccactccgcc aatcacaaag
    64261 ccccaaatga tcacatgcgt aggaacaggc gctaccaaga tttcttcgat gtttttctgg
    64321 aatttttgag agaagaagga cgaagaaacg ttggcatacg aactagtgat agcagacatc
    64381 ataatcaaac caggcacgat gaattccata tatgaaaaac cacccatgtc accgatccga
    64441 ccaccgatca tttttccgaa aataacaaag tacaaggatg tcgtgatcac aggcggaacc
    64501 agtgtttgga cccagatacg caaatagcgg ttcgtttcct tgatagctaa actttttaat
    64561 gcagtaaaat aaagattaaa catttttctc ctccgtatga ttattttctt ctgtgatttt
    64621 caaaaacagt tcttctaaac gattcgactt attcctcata gaaagaactt tgattccttg
    64681 tcttgtcagc tgatcgaaga ttccgttcac cccttgattt cgttcaactt cgacagcgat
    64741 tgtctgttca tcttcaaatg tacaagcgta tccttcaatc acaggtttgg tctcatatgg
    64801 cgctaaatca aagataaatg tttcaaattg cagtttggat agaagctctt tcatactagt
    64861 attctcgatc agttcacctg attggatgat cccgatgttg cgacaaagca tttcagcttc
    64921 ttctaaataa tgcgtcgtca aaatgatcgt tgtaccattt tcgttcaatt ctcggagaaa
    64981 ctcccacatc tcgcgtctca attcaatatc gactcctgct gttggttcat ccaagatcag
    65041 caaacgtggt tcatgcatca atgccctagc aatcatcagt cttcgcttca ttcccccgga
    65101 aagcatacgt gcacggacat ttctcttttc ccaaagattg gactgcttca aatatttttc
    65161 gctgcgtttc atcgcttctt tgcgagagac accgtagtag cctgcttgat tcacgacgat
    65221 ttgctggacc gtttcaaagg gattgaaatt gaactcttgc gggactaatc caatctgttg
    65281 ctttgctcgg actagatccg tatccagatc ataaccgaag acattcactt ttccagatgt
    65341 tttattgact aaagaagtaa tgattccgat cgttgtagac ttcccagctc catttggtcc
    65401 taatagcgca tagaaatctc cttctttcac ggaaagatcg attcctcgca atgcttcgac
    65461 cccacttcca taaacctttt tcaaattatt tatttcaagc gcatttgcca tttatttcct
    65521 atctccttat agacatgatt ctttattgta tcatggaata cagcagatga aaaaacaact
    65581 tggttccagc gaaaaatcag gttgctgggc tcaggaaaat ctcctaatga aagacatcaa
    65641 tcggacgaag tcagacaacc ttttcagaaa aaacaaatcg aagataaagg attactattc
    65701 atatgtgcaa caaaaggagc gtgagacaaa agtaaagaac acttttgtct cacgctctaa
    65761 acacgtataa acggcggaag caaaagccaa gatttttgat ccaataaata ctttcgatca
    65821 cttcgcctat cccaatacat gccactgccg cttttcatca aataacgcgg cttccgtttt
    65881 tgcggtttct actaaagtct ctgggtaatc caaaactttc agcaaggcaa tcgcatttcg
    65941 ggtccttgaa ggtccttctt ttaatttgaa atcaaaactg attccttttc cttctgttac
    66001 ttgttcttca aagtggacat tctcacaata attctttaaa atctctgtca attcgatatc
    66061 atgtgtggcg acaaatgcta aagatggata ctccgcaagc caccgaacga ctgaagcgga
    66121 agaagcaatc cgttcgatcg tatttgtccc ttttaaaatc tcatctacga agcagtagca
    66181 gcgttctttg gaagccactt ggtccaacaa acgtttgatc gatttgattt ctgaaacaaa
    66241 ataactgtcg ccttcaaata aatcatcttc gattgccatg gaagtcaaca catgtccagg
    66301 ttgcagggta aactgttctg caatcgctgt ttggatcgtc tgtgctagaa tacagctgat
    66361 ggctatactt ttgacatacg tagattttcc tgatgcattg gaacccgtga ctaatgtatt
    66421 cttctgccag ttgaccggat tcactaccgc ttcttttaac aatggatgat agatatcttt
    66481 cgctgtcaca ccgccctcag taaactctgg tcggcaagtg atgggcatat aagtacggta
    66541 attcaatatt gcagcggcta cttctaattc tcccagcaat tcccacagct tgatggcttc
    66601 agttgaatgc ttttctaatt tagtgagaac gaaatgatag gagataaatg gcagcatgaa
    66661 catgatgttg acatattcaa aaatcaactc tgcttcactc ccactcttca tacgaaatga
    66721 aaaacctaat ttagggatgt ctcttaatgg tttagtttgc tgtttcagct cttcttgaag
    66781 tggtgtcggc agttttgcta gctgattggc ggctgaaatc gttgaaacca aataactcat
    66841 gctattcagc tctgtttcta gtgtttgttt cttcactaga taatagaccg tattgaatac
    66901 taacccaccg attgccaaat agattcctag tacttgtcct aaaagaagca aacccaaacc
    66961 caccagcgga agcaagccaa gaaaaataaa taaacctacg cgtccaatct ttttactttt
    67021 tccatccgct agatattgtt ttgcaaaatt atgatctttt tttcctaaac gagcgaattg
    67081 atattggatt ttttctctca gttgaggatt ttcctgataa aaagcaatca gtttttctaa
    67141 ctgctgatct tcaccaaaat caaagctgcg taaacgttga tacaacgctt ctgaacctac
    67201 actagaatag gtactgttga ttccttcgaa tacttcgaac atatccaggt cataccaagt
    67261 aagatcatcg atttcgctat cccatgaacg gaacttcttc tccgtgagcc atgcttcctt
    67321 caagctttct tctttatcaa atctcggttg ataaggaatt ttttcccatt tgctacgaac
    67381 tgtttccttt aatttcaaac gtgaaaaaat gtctaaagca actaataaaa taacagctgc
    67441 aataataatt aaaacgataa attctctttg acccatatcc ctctccgttc ctttatttgt
    67501 tagctttagt atagcactgt tgcgctattt gaaaagaggg taaaaaaaca cctttcaaaa
    67561 taaaaggtgt ttttttcttg tatattacat atttatctct catttatcaa aattgacaaa
    67621 taatcatagg gaggaattgt tgttaattct tgtttattct ccagtgcatt gacaactgtc
    67681 ccaagggaaa ggatagcctc aggtactatt ttttcttgtt ctgttggatt agctaagcga
    67741 agaacaaatc cttgttcatg aaaataagaa ggataaatcg atgatacaat taagtcttca
    67801 ggtaattcaa tcaatgaaaa tttacgagga acatcaagtt cattttgtaa tggccaaatc
    67861 ttgttatcta acctgtgaat aaatacattc agtttctgct tttgataaga aatagattgt
    67921 tctaaccgtt tttctgcctg ttttgccact ttgaactcat taaatcttcc ttcttctaca
    67981 ttaaatccaa aagtgacttt atactcacct atctcttgag ctagcggtgt ttccatcatg
    68041 acatgccctt catttgtcgt atctcctgaa gctcgcccag gtcgccaagc aagattaggt
    68101 tttccaagtt cccctgttgt tgaaaataag gttatgatta attgattttc tatacgttca
    68161 tactctttta aaccatctgc ataaaacgta aaataatgat cattttctgc cacagagaca
    68221 ctcttatcga atatttctaa attaacaggt ttctctacca tagtttctga ccaattcgga
    68281 ggaatgacat caggggtatt ttcaataaat ccgttttgaa tttgtgcaat tgatttttca
    68341 gatttatcta aaacattaat tgctaagcgc atacgatgcg agtaaacagt attatgaatt
    68401 ttgagtgtgc cttcaacgat ttgactttct cccagactga acgatatttc ataagatatt
    68461 tcttccattt cgggtttttc agataaacga tcttttaaat ctttaggaag ttgagctttt
    68521 ccgtaaacaa ctaatgtttc ttgtaaagaa tctttatata ctttagctgt ttctaatttt
    68581 agagatagtt ctgtatctcc ttctaatggt gaataatcat acgtatcgcc atcatttgct
    68641 gaatcgatca aatgaacgaa atcaagatat tgtctatctc caactatcaa attcaattgc
    68701 ccatctttaa aagaaagttt atatttattg ttacttatct cagttttgtc tatctcgatt
    68761 gctgtttcta atttttcatt atttttctca aattcaacaa cagtgtatcc tagtgctggc
    68821 acatttacat ttatttttat gtcaagttca taataagctg gttcatcaaa atattcgaaa
    68881 cctgtagcaa tcatccgata agcatttttc cgttctggaa aataaacttc tttttcaatg
    68941 atattatagg gactaccttt gaagtgtatt ttctttgaat cagctactac atgcacgatt
    69001 ttcgatccac tataattctc agtcgttgtg ttgaaaacaa ggacttcatt cgattttagc
    69061 tttaatgcat cagccatccg ttttacaata aggttttcga ttccgtcagc tatctcatta
    69121 gcttctttga ttcgatggaa aatatcttcc gcaacattat ctgaaacaca gccaccaata
    69181 ctatcatgag cctggttttg caaaatcttt ttccataacc gacgaagtag gcctttactg
    69241 atatggatac catttctttc tgcaatcagc atgagcggct caactcgttt tagaattttt
    69301 tgttccaatt taaaattttc tattttcatt tttgttctta ctgagccaat agaacgatga
    69361 acacgagagt aaaccggctg acgaagttca cctttatatt caggtaattc ttttttgttt
    69421 ctgataactt ctacataaga aggataatct gaaataatat tgtggaattt actgtattta
    69481 ttcaacttct ctacgacttg atcaaaattt aaaatcattg acttttgatc tacacccgaa
    69541 ggtactaaaa tatctttgtt ttttccttgc atatgaagca tttcaactgc ttcatccaac
    69601 ttttcttttg caaattcagg aatatcttta attgcgtcta aggtcatcat tccagtcata
    69661 taaccaaatg gaaaattcat ggcataaaca aatttatctc ccaatccttt ccagataaaa
    69721 taaggagatg gaaccatcgt ttcaaagttt aatcctcgcc aacacatgaa attatcgatt
    69781 tctacttgat gcaaaagtgt aggcaaattc gcattgaacc caaacgtgtc aggcaaatac
    69841 cctaccatca ttggatctcc atatttaagg atcgtatcac tgattccaat cattaagttt
    69901 cttaaaattg attcagcatc cactaataag gcatctgttt gtgcatacca cggtcccacg
    69961 aatagttgtc ctgttttcat cagtcgttgg ataaccttaa gcttttgcgg attgatctcc
    70021 aaatactcat cgacgattga agtttgtcca tctaaacaaa agtttacttt agggttcctt
    70081 tccaattcat ctagaacttc agtaaagacc tgatcagaca atacgatggc atcttcattt
    70141 gtaaaatacc attctctgtc ccagtgcgtg tgttgaatta tatgtgcatt taccatatca
    70201 gattctccta ctttccttct tctactgaat ttacttgttg ttctttttta tacttgatgg
    70261 attttagtgc attgaccatt aacgctgtaa ccactccccc aataacaatt gatactaaat
    70321 ataaaggtat attcgtaaca aaaggaattg ccataaaggt tgaaagcatt gtttcttgag
    70381 taacaccaaa aaatccattt agaccacatg ctactgcagt gcccaccacg atgcttggta
    70441 ttactcgtaa aggatctttc acggcaaacg ggatcgtccc ttcagtaatc cccacaaggc
    70501 ccataatcat agctgtcttt gcattatctc gttccgattc atcataaagt tttttgttta
    70561 aaattgttgc taaaaacatt ccaaatggcg gaatagcaat tcctaataac atggctgtac
    70621 taggtccaaa gcttccgctt gaaaaagaag caaccccaaa agcatatgcg attttattga
    70681 taggtcctcc catatcaaac gccatcattc ctcctaaaat agccgacatc aaagcagcat
    70741 ttgctcctga catgccttct agccaattag tcagtcctgt tgtcattgct tgaataggcg
    70801 tagctagtac ataccataat atgattccaa caactaatgt agtaacaaaa ggaatcagca
    70861 taattgattt tagactaata acttgcatcg gtacttttac ttttttcaat gcattagcta
    70921 aatagccaca agctaatcca gcaaccattc ctccaataaa tcccatacca agattttgac
    70981 acatcatccc agtgataaaa gctggtgcta gaccgggacg gtcagcaatt gaatatgcga
    71041 tataggctga aatcatcggt acgataaact gtaatcccgt ctgaccaatc attcgcagga
    71101 ctccccagaa tgtatccgtc tggtcccaaa cacctgtgcc accaaaaatg actgcaatag
    71161 aagttagtaa ccctgctgct acgacaagcg ggatcatata ggaaacccca ctttggaaat
    71221 gatttagaat ttctcttcct tgtttcttga attccattag taactccccc acgatatatt
    71281 ttttatttgt taattaatgc aattgcttca tcaatcgtct cttcaccatc ttttactacc
    71341 tctgaggtcc ctactgttaa aatcggttta ccgtcaaagc gacctcgttc tgaaacattt
    71401 gtatctactg caaatatgac aacatctgcc tcggaaacat ccgaaattga aagtttgttt
    71461 tctatcccca tagccccctg tgtttctact ttaatatcta accctttctt cttcgcaaac
    71521 ttttctaaat tagcttttgc catataagta tgggcaatcc ctgcgataca tgctgttact
    71581 gctactattt ttgtcatatg aaattcctcc ttttaaaatg atagagcttt taccaattct
    71641 tttttatttc tcgaatcttt tattctttta acaaactcgt catccatcaa tcttccagat
    71701 aattctgcta aaatacgtaa atgattagta cctttatcag tgtcttttat tgctaacaaa
    71761 aagacgagat caactggttg atcatctaat gcgccccatt caacagaccg ctttaacttg
    71821 gctacagcca ctgttgattc aattactgct aggcttttgc catgaggaat ggcgatattt
    71881 ttcccaattc ctgtggtcat atggttttct ctgtcaaata cgtctttttg aaattgtttg
    71941 tggtcagaca caaacccatt agtctctaac aatttcgata atttttcgac tacacttttt
    72001 ttatcagatg catttaaatc tatcactata ttatttatat tgattttttc actgatcatt
    72061 tataagcctt ctttcaatat ataaactaat ttttcaaacg acgaactcgt ttttaaattt
    72121 gctaataact catgattcga agcgatttca ttgaatgttt cataaatttt attcaattca
    72181 ggttttactt tttcattaag tgcaaaaaag aaaacagaat gaacaagtgt cccatcccaa
    72241 tcaattcctt ctggattaac gtagacacag attactggct tttttataaa atctacttcg
    72301 atatgcggca tagcaaaatc attcatcgct gttgaagata gtttttctct tttgattgct
    72361 ccctctagta tcccttcttt cgcgtaattt tcttttacca attttttggt aattatattt
    72421 aaaacgttca cttgattatc ctttatttgg tgggtaaaaa agcaaaatcg tttatctaat
    72481 aaatttagaa aagcatcttc tgtttgttca tttaactgta gatactgttt tacttttctg
    72541 acatctgccc ctaacatcaa aggactaaca acaataacag gaaaatttgt attttcaatc
    72601 ggaatcgtgc ttataacaag ttcatcagtg acttttctat cttgtagttc attgatgctt
    72661 agtacatctt ctatctcaac catatctgca aaaccgttat ttattctttg ctctaataat
    72721 tttgatgttc catatccgct actacaaact aatatcactt tcgttttgtc aggtttgtaa
    72781 cgatccaaaa gtgattgaat atggagtgtt acgtaagcga tttcatcttc attaaaatgt
    72841 atacagaatc tctcttcgat ttcctctaat aaatctacac ttatcataaa tgacctttta
    72901 aaagaatatt tgattttgtc cgtataaggg ttatagatat ttactcccaa tttgagtctt
    72961 ttaactgctg cattgagatg taatactaga ttattgatca attcttcatc aggataaaat
    73021 tcatttaatt taattcttac taactcttgt agctcaacac ccatatctaa ataggaaagc
    73081 ttcgtttgat ctaagtcgtg attcatagca tttttttcaa tcgaagtaat gtgaatgtca
    73141 acataagctt gttcatctat tggcacaata attgaaaatg ctttttcaat cattttgatt
    73201 aaaataagtg tattctttga gatttcttct tcagaattat tactacgtga taagaaattg
    73261 cttgtttcaa tcctttctat cgcaatagca aggtggatag ctaaagtttg aaattcataa
    73321 tctgtaaatt tcaattgtgt cttattcatg tatcgattaa gcaattcggc tacttttttc
    73381 aatatgtcct tatttaagaa attattcgct tcaccaatga aattgatatt caagtctaag
    73441 agatctgttt tactgttaga tgctgtaaag ccaccccaat aatagttcac aacttctgac
    73501 atcaaccttc ttttactttt ttcatcagct ttgatgcgca cgccatttcg atctgaaact
    73561 aaggacatcc catgcttgtt tagtcttttt ctaacatctt tcattgtgct ttctaccgtc
    73621 gacctgctca cgtataattc gtcagcaaga ttttgaatct ttagagaatc attagtattc
    73681 aataatttag caaacacata agttagacgg tcctccggag agtctgcgat attgatttta
    73741 tgactggata ataaatttcg aagtgtttct ttttttccaa taagcgaaac gcctttttta
    73801 ggttgaacca acatttgtac atctggcatt ttttggatta tttctttcaa aattaaaata
    73861 tctttgctaa ttgttttcgt agatacatat aattgttctg ataattcttt gtaagttgtg
    73921 tgctcatttt caatcaaaaa gtatagtatt ttcatttgcc gttcgctaaa ttcgatgccc
    73981 attatcttca cctcctgaat acagcttaag tgtacaatta ttatctctat tttcatacag
    74041 aagaaagttc ttgattaatg tagaagtttc taatattctt gattatttca aatcaataaa
    74101 aaagcctgca atatttatat cacaggcttt tttctctatt aaatatatat aagataatac
    74161 atttttctac tagttctcac taatcttgta taattaaacc ctccgcaact tgacggagat
    74221 ggagaagatg cccccgtcta atctagcggt catctctcct cccattcctt ccaccaattt
    74281 ttttgacagg taaagcccga ttccgctaga ttccgtattt gtgcggctgg tattttcggt
    74341 ataaaaacgc tggaagactt tttcaacaga ggtttgcgtt cctggtttga taggattggc
    74401 cactgttaat cgaatgaatg gatcctcttt tgaaaatgtc acctttgctt gtccatctgc
    74461 ataacgcaat aaattctgta tgatattttg cagcactcgc agcaacatga gcggatctgc
    74521 taatacagtt gtatttatcg agtgttcagc gaacgctacc tcgatatttt tctcagaaaa
    74581 ttgttcataa aaagagaaaa atacttcttc cacctcttta gaaaaagaaa gcgtatggag
    74641 atccatttct ttttgcttcg tctctattcg agcaagatca taaaactgat ccgtcatact
    74701 gagtaatctt gcaacagatt gtttgatgat cgttaaatac ttctcccgtt tctccgtatc
    74761 ctctacctgt tccagtaatt gtacataacc gttaatagca gtcaaaggag ttctgagatc
    74821 atgagaaagg ccgacgatcg atagtctgat gttttcttcc atttcttgaa atgcttgtcc
    74881 tttttgttca ttttcatcca accatgtatt cagtgcatct actaggtcca ttagattctt
    74941 ttctcgaaat tcgactgaaa gacgaccacc atattcttgt cgttcagaaa gagtggcgat
    75001 tttcttagtt aatctcttga tttccctttg caggaagaaa ataaaacttc ccataaagat
    75061 aacaacgaga agcaacagcc atttaatcaa atctaaaccc cactccccac accgtatgaa
    75121 tatacacagc atgtgccttt gctagcttcc ctcgaagatt ggaaatatgc atattcactg
    75181 ttttctcact atcaaaatat ggttcttgcc aaactgtttc ataaagattt gctcgcgaaa
    75241 atactttttt cggatgttct aaaaaaagct tcagcagatc gaattctctt cctgtcaaat
    75301 ggacagccac accattcaca tttacatccc tcgactcttt gtccagtaag atttccttgt
    75361 aatagatgcg ttgcgacaga tcttttactt ggacagaagt ctgatgacga agttggatgc
    75421 cgattcgtaa caaaagttct tcgatatcaa atggtttcgt cacatagtca tccgctcctg
    75481 ctgccaacaa ggaaacttta tctctttgat cgctttttgc tgaaagaacg atgatcggaa
    75541 cattcgatgt ctgtcggatt tctgctaaca atgcttcacc tgaaagccct ggaagcatga
    75601 gatctagaag gatcaaatcg acaggatatg tgcttaacaa taattttcct tccgtacctg
    75661 aataagcatc aagaagtttg tatctctgtt caagaacctc ctccagtaag gaatgaacag
    75721 cttcatcgtc ttcgataatc aaaatagttt ccagcaggac cacctactta atgtcagatt
    75781 tttggaaaat aaacattcct agagctgatg ataccacgat tgttactaga ctgaccagaa
    75841 tcattttcgg tgcttgcgaa taagttgctt gttgcgcaaa gtccgtatac atgagccacg
    75901 tttccgtaaa ccactccgtt agaaattcca agcctttgat ttttgcgaaa acaccgggaa
    75961 tgaaggccgt tcccatgata taaagaaaag aaagaagcaa actgacactg gtacttctag
    76021 tgatgaatgt caaagccact ggaacagata atgtccctaa tgtcagcaga agcaatacag
    76081 gaaatacttt tagaacataa tttccatagt ttttgattcc ctcaacttca ccaaatccga
    76141 aagcaagtgt gtaagcaagc atggctagtc ccgtgatcaa aaccacgcca agtgttgtga
    76201 tcaaaagcgt aacgagaagt ttcgacacat aataagtcat tcgattccgt cctaaagata
    76261 acgtattgcg aatcgtaccg ttttgaaatt cttccccaat ataaaagcac gcaaatgctg
    76321 cgaaagccag aagaatccat gcagccattt tttctaccat taaaatccct gttgcaccgt
    76381 tgatgactgt atccgttgct tggtttaatt cattgccgta ttttgtatgc atataccatt
    76441 cgttccaaga ataaaaaagc ggaagtacga ccatcagtcc tagtgagacc cacattttac
    76501 ggctcttcca tacttttatt ttttcagcag ttaatagatt aaacatgtgg attgcctcca
    76561 gttaattgta agaaataatc ttccagtttt tgcccaacta ggtgaatacc atccacagga
    76621 acttttgctt ctaccaatgc ttgattgatg gctgctactt ggtcaattcc ttcaaaaagc
    76681 tggataacac ggctagattg tacaaaataa tccctataac caagagagtc gagaaccgtt
    76741 actgcttgtt ccgtcgccga agtgtcaatt tttataaatt gacgagattc ttgtgccaat
    76801 tcttctttcg ataattcttt gatcaagtgt ccttcatgca aaataccata gtgagtggcg
    76861 atctgtgaca attcatctag caagtggcta gaaagcaaga cggtgatgcc ccgttctttt
    76921 accaaacgtt ggatgatttc tcgcatttct gccatccctg ctggatccat cccattcgtc
    76981 ggttcatcca aaatcaaaaa ttctggattc gtgatcagtg catttgcaat agctaaacgc
    77041 tggcgcatac ctaaagagaa attctttgct ttctttttcc ctgtattttc caatcgcatc
    77101 attttcagca ggtcttcgat ttctctatcc gacacaccgc cgttcgctgc ttggatacgt
    77161 aggttatctc ttgcagttaa ttctggataa agagcagggg tttcaatcga ttgacccata
    77221 cgtcgtcttg ctgcctgcaa atccgtcgtt ccaaataatt cgatcgaacc ttcatcaatc
    77281 gagatcaaac ccataatagt tctcataaag gtagacttac ccgctccatt ttccccaatc
    77341 aatccataga tcattccacg tttgatttcg attgatactt tatctaatgc tttggcagca
    77401 ccgtattttt tggttatacc agttgctttc aagaccgttt catttccaaa atccatactt
    77461 atccttcttt cttattgatg agtgaagtat agttgacggg tataaagaaa gcagccagaa
    77521 atgtataaag aaagtgtaaa ttttccaatt gaatgtcaaa aaaaacaatc ggacaatacg
    77581 tgtctttcct attatcaggc agtttgttat acgcttgtat cagtttcctg attctttctt
    77641 ttcgaccaaa gtcgtttctc tgtattcctc ttcactgaaa atttttgctt ctttcagatc
    77701 aagcttgagt aattttacca gaccggttat aaggataact atagcaagac tccctcccag
    77761 aaaaattaga ctgtctcgca gacgtggttg cgttgtcttc caatcaaaga gcgcaccaaa
    77821 cagtgctaat ccaagtggac tggccaccat ggtaatcgtt gttatcgttg acataagtcg
    77881 tccttgtata tgcgttggaa cttctcgctg aagccagacc atataaaaag caaaagaaaa
    77941 cattaatcct taaaaacgga cttatgaaaa ataatacatg ccgtttggga tttacaatta
    78001 gctaccaaat aagaggttat gacaaaagac ttttcacaat cccttcttcc gaataaacgg
    78061 tgttctcctg ccaactcctc ggtcacaagt cacaatattt atcaaacatg agaagcaatt
    78121 tttgtaaatt ccttcttatt tcttgaagct gaccacttct gtcacaacct cagaagcgga
    78181 taaataatat tgtttgatga tactttatct ttttcccgtt tgtttataga tcgaatgata
    78241 ttatagacca agaatcctac ctattaacat agctaaaaac acaaaaaagg cactttccaa
    78301 attgtggaaa gtgccagaaa agttaggatt aaggtaactg cgctcagcat tgcttcgccc
    78361 agtacgattc tcgtaactcg tgaactcgaa cgataatcgc aattaacgtt ttgagaactg
    78421 tgaagcttta cgggctttct taagacctgg ttttttcttc gtatcattga ataagtttga
    78481 aaaaccttga tttataaagg ttttcccgta aatatatttt attatatttg attaaatttg
    78541 aaatgtttgt gttctaaaat gtgttctaat ttaaaggcag tatatttcgt attttagatt
    78601 aaatttttag gctcattcat tctcaaatcc attctattca gtcaataaaa attttaaaaa
    78661 gactttataa acaaagatgt tcaagcgagc atcttatttt tttgtgctta atttgaaagg
    78721 agaacatttc atgtataaaa aacaaaaaaa gaaattatgt gtattaacta ttttgagttt
    78781 ggctgttcaa gcaattgttg gagcaattgc tcctacgatt acttttgctg atgaaattac
    78841 ccatccacaa acggtaaccg tagaactaga tttagcacat caatatgctg ttgaaggaac
    78901 ttttagtgat ggtcgtccaa tgtcagaagt cactgttccg cattatgcag tgtacaacgg
    78961 ctttaaacaa gatattttct gtattgaacc aggagtcccg atttacaatg agttcactcc
    79021 tggctatgag aaaaacccgt taccagatat gtccgataaa gccaaattag tttccgtttt
    79081 atggaaaaaa gtaggtacag atgcagatac tcatattgtg gcacagaaga tgatctggca
    79141 agaagttaat gggtataccc ttcactcaat aaaacgatca gatggtagtg ccgtaaatat
    79201 cgcagccatt gaggcaaaaa taaatcaagc cattgacgat tatcagaaga aaccaacctt
    79261 ccataatagt acggctaaaa cagtattagg gcaatcgact actgtgacgg atacgaataa
    79321 tctgaatttg tcagagttcg atgaggttgt ggaaaatgcc gcaaacattg attatcgtgt
    79381 gaatggtaat cagttgataa tcaccccaaa tgccaattca aaagaaagtg gtgtgctgac
    79441 gcttaagaaa tctgctggta ccggaacacc tgtcgcctat aaaaaggctg gccaacagac
    79501 tttaatggcc ggggcgattg ataaacctaa tacctacaca atcaaaattg atgtggaaac
    79561 ggagggttct ttaaagatca aaaaagtcga taaagaatcg ggtgatgttg taccaggaac
    79621 ggttttccat ttagactttg gaaaaacttt acctgcaaaa gacgtgacta ctgacaaaga
    79681 aggcattgct acattggatg agattcctca tggtacaaaa gtaaccatta ccgaaaaatc
    79741 agtaccggcg ccttatacga ttgataccac ccccatgact accaccatta aagcaggcga
    79801 aaccatttac gtgacttcaa aaaacgcacg ggaaaaaggg caaatcattc tggataaaag
    79861 cggagttgaa acagggagtg atctttggaa tgacaattat tccttagctg gtaatacgtt
    79921 tgccattcgc aaagacagtc caaccggtga aatcgttcaa gaaatgacca cggatgaaaa
    79981 cggtcatgcg gaaacaccaa aagagattgc taatgcgttg gaattgggaa cctattatgt
    80041 gaccgaaact aaagctagtc atgggttcgt gaatacgttc aaacctgtaa aagtcgaatt
    80101 gaagtatgcc aatcaaaccg tagcccctgt taccagtaac gtaaaagggc aaaatcaaga
    80161 agtcactggc gaaaccactt tgacgaaaga agacaaagat actggggata aagcacaagg
    80221 taaggcagtc tttgagggtg ctgaatacac cttgtttact gctaaggatg gaaaagctgt
    80281 taaatggagt gaggctttta aaccagagtt agcgaaggga acgaaaggtt ctgatgaaac
    80341 ggtcactttg actttagacg aaaagaacca agttgccgtt aaacatttag ctatcaacga
    80401 gtattattgc caagaaacaa aagcgcccga aggatatagc cttgatgaaa caaagtatcc
    80461 tgtatccatc aaaaaggtgg atgatagcga aaaaaatgcc gtgattaccc gaaatgttac
    80521 ggcaaaagaa caagtgattc gctttggctt tgatttcttt aaatttgctg gatcagctgc
    80581 gggcactacc gaaactggct tcaatgatct gacctttaaa gtgtcgccat tggaagggac
    80641 caatgaaatc acaggtgccg aagatgaagc gaccacagct tataacgagc aattagggtt
    80701 tgatggttat ggcaagtttg aaaatcttcc ttatggggat tatttacttg aagaagtaga
    80761 agccccagaa ggttttcaaa agattacgcc attagaaatc cgttctactt ttaaggaaaa
    80821 caaagaagac tttgtgaaga gtgagtatgt ctttaccatt accgaacaag accaaaaaca
    80881 accaattaaa acggtgaccg ttccttacga gaagctgacg aacaaagcat tttctgttag
    80941 tttgaaccgt ttaatgctct atgatttgcc tgaggaagaa gatagtttaa cttctcttgc
    81001 gacttggaaa gacggaaaca aagaattaac ttctctggat tctaccgagc tagttgataa
    81061 attgagttac aatctacatg aaatcaaaga agactggtat gtggtagcgc aagccattga
    81121 tgtggatgcg acaaaagctg cccaagaaaa agatgaaaaa gccaaaccag tggtgattgc
    81181 agaaacaagc gcaacgttgg cgaacaaaga gaaaacagga acttggaaaa ttcagcataa
    81241 attaaccgcc gaacaagttt taaataaaac tattgtctta ttcaactatg tgtatgaaaa
    81301 taaggaagct tttgaagcag gcgataagcc agtagcgaag gatgttagct tgaataacca
    81361 agcccaaact gtcagttgta cagtggaaca ccatgtttct atccaaacaa aggcccacct
    81421 agaaaacggt tctcagacct ttactcatgg tgatgtggtg gatatgtttg atgatgtgtc
    81481 gattactcat gatgtactgg atggctcaaa agaagctttc gaaacaattc tgtatgcttt
    81541 attaccggat ggtacaaaca aagaaatttg gaaatctggc aagattgatt atgaagtaaa
    81601 tgataaagaa ttcaccaaaa ctgtgcttgc gaaaaaagta gataccggaa aatatccaga
    81661 aggaaccaag tttacttttg cggaaatcaa ttacgataaa gatgggaata tcaatggaaa
    81721 acacaatgaa gatttgaaag aaaaatctca aaccttaaca ccaaaagaag ttccaaccat
    81781 actaagtacg ccgaaacaac cggaaacacc aactgttcca agtggctctc aagaatctag
    81841 tcccacagtg aagaccttcc ctcaaaccgg ggagaaaaat tccaatgttt tactgttcat
    81901 tggttttact ttgatttttg cgacggcggg ctattatttc tggaatcgcc ggaactaagg
    81961 tgatgagatg atacaagtaa atcctaagaa ccaacgtgcg cgaccgcctc ctaaaaaagt
    82021 agtcgcgcta tttttgtatc caaaactaac aatgaaaaga ggaaaagaag atggaattga
    82081 aatttgtcgt gccagatatg gctgaaacct ttggaaagtt aagttatgcc ggtgaaggag
    82141 aaattataac agaaggatat ggacggaata ctacggtgat tggtcgcagt tatcatttgt
    82201 attccagtaa gcaacgggcc gatgatattg aggtggtagt agctgcggaa gccggtgaaa
    82261 aggattttga tcaagaccaa ccgctaaaag ccgtgaatcc ccatttggtt gccaaaggct
    82321 atgagattga gaatcgtggg tttactgatt acgtgttgta tgttgatgat ttagtgaaag
    82381 cataggagga aaagaagatg agattaacag aaggtattgt cgtagattca ggtttaacat
    82441 ttgggaagtt gcgtttttcc gcattacgcc gagaagtacg gaagcaaaat gaggatggaa
    82501 caattggtaa tgaggtaaaa gaacgaacct ataatttaaa atcctctgca caagggcgaa
    82561 tgattcaagt tagtatccca gctaatgtac ccttacgcga gtttgcttat gatgcagagg
    82621 tagagttggt caatccaatc gtggataccg ttgccaatta tgtttttcga gaaggaacta
    82681 ccgttaattg gttcattaag gcggatgatt tagtcttgaa gcggcagccg aatcaaggaa
    82741 atcctacgaa ccaaaatgaa agaaagaaat aggtgaagat tatggaaatt aatgttgaac
    82801 atattttaga ttgtctcgat caatatggaa aaggcgagct gactgaggaa caactcgtta
    82861 aagcattaac ctctgatgaa aaaatgtttc tgattataca tcaaggttta cttggagaaa
    82921 atagcgacag tgaagaagac tctgatgtac tagactggtt aggagaagaa gagtctttct
    82981 ttatagttgt cgaagtaaat gaaaacttat gtcggcaggc agaatccatt ttggaagaaa
    83041 ttggtgtgga gatgccggat gctattgaag gctttttaaa tcaattggtt gaaacgaaac
    83101 aactcccctc ctcgtagcag taaatgacta gcataacttt ttgaaattgc ctaatgaaat
    83161 cctattgggc tttttcgatt ggaggtggaa accatcaaaa tgtacaaagg acatcgcata
    83221 cgcgcaggag atcagcactt ggtttatcac tttgttcttg gctggctact cgctctgttc
    83281 atcggttgga tgagcgtctt ttattttcaa gagtttagac aatttgatat ttctaagcta
    83341 tcactttcta ctattgaaat cgtttggtct ataaaagatt tagtatgtct gcttggaagt
    83401 ctcgcttttt caggagctat gatattgctt tatattcact tttttcttga tcattggcga
    83461 agcttgtggc atcgacaaaa gctagctcgg atgattctag agaaccattg gtatgaagtg
    83521 aaacaaactc aaagtgaagg ctttttcaaa gatttgaata gtagccgaac cagagagact
    83581 atcagttact tccccaaaat ctgttatcga atgaaagatg gattactgtc tattcgcgtt
    83641 caaatttcac ttgggaaata ccaagatcag cttttaaaat tggaaaagaa gttagaaagc
    83701 ggactgtatt gtgagttagt agaaaaggaa ctcaaagact cctatgtgga gtatacttta
    83761 ctgtatgata tgatcgccaa tcgaattggg atagacgaag tagtggcaga aaatgggact
    83821 ctgcgattga tgaaaaatca agtatgggct tatgattctt taccccatat gttaatcgct
    83881 ggtggcacgg gtggagggaa gacctatttc ctcctcacca ttatcgaagc actattgaag
    83941 tcagatgcag aattgtttat cctcgatccc aaaaatgcag atttagctga tttaggtacg
    84001 gtgatgcctc atgtttattc acaaaaggaa gaaatttctg cttgtgtgga agatttctat
    84061 gaacgtatga tggctcgtag caaggcaatg aaagaaatgt ctaactacaa aacaggagag
    84121 aattatgcct atcttggact tccacccaac tttttaatct ttgatgaata cgtggcttat
    84181 atggagatgt taacgacgaa agaaagtgcg gtgattttga ataagctcaa acaaatcgtg
    84241 atgttgggtc gtcaatctgg tttctttctg attttggctt gccaaaggcc ggatgcgaaa
    84301 tatttaggag acggaatccg cgatcaattc aactttcgcg tggctttggg tcgtatgagt
    84361 gaactcggat attccatgat gtttggggag gtcgaaaaaa acttctttat gaagcacatc
    84421 aaaggtcgag gttatgtgga tacaggtggc agtgtgatta gtgagtttta tacgccactt
    84481 gtaccaaaag ggtatgattt cttagattca attagtaaat tagaaaagat gaatgattga
    84541 gtgatcttca atactgactt tatacttcaa gtaacgtata atacttttat atagtaggaa
    84601 gaaaggggat aattaatatg gaaagtaatg attcttattt agagtatgca aaagcaaata
    84661 aggataagtt tatttcttat attatcaaag ggaaatcccc cgaagttgga cgagacgcag
    84721 tttttatggc agggagtcct ggggctggaa aatcagaggt tgccattgga ttagctgaga
    84781 attatgataa ccatgtgatt attgatgcgg attactttcg cacccagttt cctgattata
    84841 atggaaaaaa ctctagtctc tttcaaaaag catcttcttg gttggtagag caggcattta
    84901 gatatgtctt agatcatggc tattctttta ttctggatgc aacttttgca atattaagtg
    84961 ctgaaaaaaa tatctcgcgg gcgttgaaaa aacattttcg agtgacgatt ttctatgttt
    85021 atcaagaccc taaaatcgct tggaaattta cacaagaacg tgaaattgca gagggacgtc
    85081 atgtgccgaa aaaggcattt attaacgctt ttttcaaatc aagagagaac attgcaaaag
    85141 taaagagtaa acatccagat gtattgcttc atatcataat aaaagattat acgaataata
    85201 tttccgaagt tcattatgct acggataatc tagaattatt tttaccacta gggtatagta
    85261 ggaaagattt ggaggttcaa ttacatgact gagaaagaac aagtaacgaa aattgtaaag
    85321 aaatacaata agagcattgc ggatttatcg gaaaatgcta ctgcaaaaga gttcaaaacg
    85381 gtgattaaat atgtagccga tcaggccaat gaaaaacaac ggaaattagt tggattaaat
    85441 aaaaaatagt aggacaaatt aataatgtat gagccaagag caaaatgttc ttggcttttt
    85501 tctttgcaat gaatgaggta atgtatgaga tttttagatt tattcgccgg tattggtggc
    85561 tttcgtttag gtatggaaca ggcgagccat cattgtatcg gtttttgtga aattgataaa
    85621 tttgctagac gtagttataa agcaattcat gatacaagta aggaggtgga aatgcatgac
    85681 atcacaagtg tatcagatga gtttattcaa tccctcggac cagtggacat cctttgcggc
    85741 ggatttccgt gccaagcttt ttcaattgcg ggaaagcggc aaagattttc cgatactcga
    85801 ggtactttat tctttgaaat cgctcggttc accactcttc tccgacctaa gcttttattc
    85861 cttgagaacg tccgaggatt gctcaatcac gaaggagggg ctacgttcga gacgatcctc
    85921 cgaacgctgg atggattggg gtatgacgtg gagtggtagg tgcttaactc aaaggcctac
    85981 attccccaaa gccgggagcg gatattcctt atcggacatt ctcgagacgc atgtaccgaa
    86041 caagtatttc ctatcattgg accgtcttca acatctgatc aaaacatcag aaatttggta
    86101 aatatcaatc cttccaatcg aggaatgggt ggacaagtct atggttcaga tggcgtagcg
    86161 ccaaccttaa caggtgatga aggaatcaaa atcgcactgc cagcaaggga tggaatctct
    86221 gtagcaggac tattaccggg aaagtttgaa caaggtaatc gagtttatga agttactgga
    86281 accgccccca ccttgtcaac gaaacaaggt ggtacaaaaa tcatgattcg aaaaaatgaa
    86341 acagaatatc aagaggtgaa gccagaagac agtgtgaatc tggcttttcc taattccaca
    86401 agtcgccgag gtcgtctggg aaaacagagt gttcatacct tactaacagg agaccaacaa
    86461 gcgatcgtca cggatcagta tcaaattcgg aagctaacac ctagagagtg ttggcgactt
    86521 cagggctttc ccgattgggc ttttgatcga gattctcaag tcaattcaga tagtcagttg
    86581 tataagcaag ccggaaactc tgtaacagtt ccggtcattt ttgatattgc cagaagatta
    86641 aaagagttgg atgtacatgg tttatgatga gttgattgga gaaatttatt gggtgattgg
    86701 aaagattcag tcagacccag aattagaaga acaattgcga cggttaaaat ttgatattcg
    86761 caagaatggt gtcaaagtcg ctggcgatcc atatttaatg aatgaggaga cggatgctcg
    86821 aattgaaata aatcaagtaa ttgcagaatt tgagcggatt gcggaccaag caaaagaacc
    86881 agatattcgt caatacttgt tagaaatgaa agcagagttg gaagtaaatg gtattacaga
    86941 tgagtaacct aaaccaacac aactgactgt taggcgctga ccgcggagga ttcgcgaagc
    87001 agaaatcctc cgtggtgctg tgcctgttca tggacggcgt tagccgacca tgatgtctca
    87061 cccccgtatc taacaggggg gtacaaaaac acaaaaaata agtaagcaac cattaagaat
    87121 gcttgttgta tcaaagatag taagtaattt gtataggtgt taactcattt gaaaaagtta
    87181 acaccttgaa tttggaggtg agaacttggc acaacggaat ttagattatc ggctattaaa
    87241 agaccgacgc aacgaatacg gcgtttcaca aaataaattg gctacggctt gtggacttag
    87301 tcggccgtac ttaaatcaga tagaaaatgg tggcgtaacc gcatctataa aaaccatgag
    87361 gaaaattttt gaccaactgg aaagctttaa tcccgatttg cctttgacgt tactgtttga
    87421 ctatgtaagg attcgctttc ccacaacgga tgcacgaaaa attattcaag aaattctcca
    87481 tttgaaattt gagtatatgc tccatgaaga ttatgccttt tactcctatc aagaacagta
    87541 tgtcatgggt gatattgtgg tgatgttgtc tcatgaagaa gataaaggtg tgcttttaga
    87601 attaaagggg cgaggttgcc gacaatttga aactttttta ctcgctcaaa agcgtagctg
    87661 gtacgacttt ttcgaggatt gtctaaaggc cggtggcgtg atgaaacgct tggacttggc
    87721 aatcaatgat cgagtggggc tattggatat acctgagcta acgaaaaaat gtcagaagga
    87781 agaatgtatc tccttgtttc gtacctttaa aagttatcgt tccggggaac ttttaaaggc
    87841 tgatgaaaag gacggcatgg gcaatacctt atatatcggc agtctcaaga gtgaggttta
    87901 tttctgtttg tatgaaaaag actatgaaca atatatcaag ttagggattc cattagacca
    87961 aactgagacg aaaaatcgtt ttgagattcg actgaaaaat gaccgtgctt ttcatgcgat
    88021 tcaagatttg ttaaaaggtc gtagcattga gagcaccacg ttttccatta tcaatcgtta
    88081 cttgcgattt gcggataaag tagaaggtaa aaggcgaacc aactggccct tgaatgaaca
    88141 atgggggcgt tttattggac ggaatcggaa agagattcaa ttaacttccg agccaaaacc
    88201 gtataccatt gaacgaacct tgaattggct aggccgacaa gtcgccccta cgtggaaaat
    88261 ggctaaggag ttggatcgat tgaatcggac aacctatatc caggatatgg tacagaatgc
    88321 acgcttatca gaccgacata aaaagatttt ggagcaacaa agtatggcaa ttgaaaattt
    88381 gattatatga aaagaggaat cgtcatggga attgtaaaag atattttttt ggtatttggt
    88441 ggcagtatgc ttggtgttac tgtgatgtgc ttgatgaatg caagtgcagc agcggatcga
    88501 gcaatggaaa agaaaggaaa gtgacaagat gaatttcgga caaaatttat gtgcgactcg
    88561 ttccttagtg aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa
    88621 ctgataatct gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc
    88681 gacaagcatt gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat
    88741 accgtaatag ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta
    88801 tccaacaggt cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg
    88861 aaacagcgaa tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc
    88921 gtagctggtg tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg
    88981 tatcaagcca gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat
    89041 cggaacgagg aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc
    89101 agttgaacta atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga
    89161 ggaatgccct caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac
    89221 gagtaagata aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa
    89281 taaaaatgaa acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa
    89341 cacctttgat gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga
    89401 tattatccta tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg
    89461 cagtaaaaca gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga
    89521 aacagttgtc aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa
    89581 gccagtgagg cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc
    89641 ttgtatgtgg gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga
    89701 agctaaattt agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat
    89761 aaaagcaacc tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat
    89821 taagggtttc tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg
    89881 aatacgggac aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat
    89941 gactaacggt acaataacat atccagagaa aggaactccg caagggggaa taatatcccc
    90001 actactagca aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga
    90061 aaatcctgtt acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag
    90121 caacgcttac aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc
    90181 agatgatttt agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat
    90241 cactcaatgg attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt
    90301 aaatgttaga aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag
    90361 aaagaagtta gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa
    90421 gctggtatca caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga
    90481 aacaagactt tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa
    90541 tgtaaatctg gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt
    90601 aggtacaaac aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc
    90661 aacaagatat ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt
    90721 ccctgttgga tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta
    90781 cactctagag ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta
    90841 ccagttaatg aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc
    90901 gctattttct gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa
    90961 tgaaatacat tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa
    91021 tcttattttg gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat
    91081 acaaaaatat atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata
    91141 tagagtatta gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt
    91201 tcaatataaa cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg
    91261 gggaaaagtt tgagatattt ataatatcag gaacttacct atccatatat caatggtttt
    91321 taaccaatgc ccaatcctta gtcttactgg caattgtggt cattggtttg tttttaggat
    91381 ttaagcggga gttttccaaa ctgattggct ttttggtgat tgctttgatt gcggtcggat
    91441 tggtctttaa tgcttctggg gtgaaggatg tcttactcag tttgtttaac cgaattgtcg
    91501 gtgcgtaagg gggaagcacg atggaacaga tgcgtgttta tattgcgaac ctcgggaaat
    91561 ataacgaagg tgaattggtg ggggcgtggt ttaccccacc tgtcgatttt gatgaagtga
    91621 aagaacgaat tgggttaaat gacgaatacg aggaatatgc aattcatgat tatgaacttc
    91681 cctttgagat tgatgagtat acgccaattg aggaaattaa tcggttgtgt ggcttagcgg
    91741 aggaacttga aggaacgcca gttggtgaag ttgcttctga gattcaacat gctttcttca
    91801 attcttttga ggagatggta gagcatgtgg atgatattat ctattatcca gattgcgatg
    91861 atatgagtga tgtagcatat ttcttgattg tagaagctgg tgattttgga gaagtaccag
    91921 aacacttgaa gacgtatatt gattttgatg cgtgtggtag agacttggag attggaggca
    91981 attatttggt aacgagtcga ggtgtttttg agtatccata ttaacaaaat tattgaaggg
    92041 tagttgattt ctaaactatc cttcttttta aaggaatgat ttgatgaaga aaataaaaag
    92101 ctacaccagt atttgggcag ttgaaaaggt catttatgca attaatgact ttcaactgcc
    92161 ttttcctgtg acttttaacc agatggcttg gtttgtttta tccttgctgt ttgtcatcgt
    92221 atttgcccat gtgcctccac tatctatgat agagggggcc tttttaaaat acttaggtat
    92281 accggtggca gttacttggt tcatgtcgca aaaaacgttt gacggtaaga aaccattggg
    92341 atttttacga tcttttatta gctatcactt acgatttaag gtcactttcg caggaaagaa
    92401 agtcaaagaa cagaagaaac gatgggacga acccattact ctggtaagga gtgtgaacta
    92461 tgtacccgat taagtatatt gaaaataatc ttgtctttaa tcaagaggga gaatgttttg
    92521 cctactatga gttaatacct tacaattact cctttttgtc acctgaacag aaatatcaag
    92581 tccacgataa ctttcgtcaa ttgattgcgc aaaatcgtga aggcaagatt catgccttac
    92641 aaattgccac agaaagtagt attcgtgcca cgcaagaacg atcaaaaaag gaaattaccg
    92701 ggcgattaac agaagtagcg aaacaacgaa ttgatttaca gacagaggca ttagtatcca
    92761 tgattggcga tagtcagatt gattatcgct tttttattgg cttcaaactg attgcgacag
    92821 atgaagaggt caatctaaag aatctcaaga aatctttctt ctccggcttt caagaatttg
    92881 tctatggagt gaatcatcat ttgatgggcg attttgtttc cttatccaat gaagaaattc
    92941 gccgatatac caagcttgaa aaactaatgg aaagtaaatt ggctcgaaga tttaaagtca
    93001 gacgagtcac accgagtgat ctgatgtatt tgattgaaca tatctatggc gaaaagggta
    93061 caccatttga agaatatgaa tttcagctac caaagaaaaa gctgaagtcg gaaactttgg
    93121 tgaaacgtta cgacttatta cgtcccagtc gttgtttgat tgaagaaaag ccccggtact
    93181 tatgcatgga acatgagaat catgaatcat atgtagcgta cttaacaatt aatacaattg
    93241 tgggggaaat ggagtttccc tcctcagaac ttttctatta ccagcaacaa caatttacat
    93301 tcccaattga cactagtatg aatgtggaga ttgtgacgaa caaaaaggca cttgctaccg
    93361 ttcgcaataa gaaaaaggaa ttaaaagact tggacaacca tgcctatcaa tctgacaatg
    93421 aaacaaattc caatgtctta gatgcattgg attccgtaga tgaattggaa actaccttgg
    93481 atcagtccaa agaatccatg tacaaactga gctatgtggt tcgagtaagt gccgaatcag
    93541 tagatgaact aaagcgccgg tgtgatgaag tgctagattt ttatgatgat accaatgtaa
    93601 aactagtccg gccttttggc gatatgatgg ggctacatga agaattctta ccttctagta
    93661 agcgatacat gaatgattat atccagtatg ttacgtctga ttttctcgcc ggacttggtt
    93721 ttggcgccac tcagatgtta ggggagttgg aaggcattta ctttggttat aacgtagata
    93781 cggggcgcaa tgtttacctg aaaccggcat tggcctcaca aggggtcaag gattcagtta
    93841 ccaatgcgct agcagcggca ttcctcggtt cactcggtgg cggaaagtcc tttagtaaca
    93901 atctcttagt ttattacgcc gtcctttttg gtggacaagc tgtgattgtc gatccaaaag
    93961 gggaacgggg tggctggaaa gaaaccttgc cagaaattgc ggatgaaatc aatattctca
    94021 acttaactag taagccaaaa aatcaaggat tacttgatcc ttatgtgatt atggagaaaa
    94081 agaaggattc tgaaagtcta gcaattgata ttctgacctt tttaacagga atttctagtc
    94141 gagatgggga gaagtttcca gtgttgcgta aggccattcg gacggttacc caaagcaatc
    94201 aacggggatt attacaagta attaatgagc ttcgaaaaga aggctcacca gttgcggaaa
    94261 atatcgcgga tcacatcgag tcctttaccg attatgattt tgcccatttg cttttctcag
    94321 atggttcgat tacccagtcg attagtttag ataggcagtt aaatatcatt caagtagcgg
    94381 atttggtttt accagatgca gaaaccactt ttgaagaata taccaccatg gaattgctta
    94441 gtgtttccat gctaatcgtc atttccactt ttgccttgga ctttatccat agtaatcgag
    94501 aaatcttcaa aattgtagac ttagatgagg cgtggagttt tcttcaagta gcgcaaggga
    94561 aaacattatc gaataagctc gttcgtgctg ggcgggctat gaatgccggg gtttactttg
    94621 tcacgcaaaa tagtgatgat ttactggatg aacgcttgaa gaataatatc gggttgaagt
    94681 ttgcgtttcg cagtaccgat attcatgaaa tcaagaaaac cttggaattc tttggcttgg
    94741 atcgagaaga tgaaagcaat caaaaacgcc tacgagattt ggaaaatggc caatgcttga
    94801 tgcaggattt gtatggtcgg gtaggcgtgg ttcaggtaca tccagtcttt gaagaactct
    94861 tccatgcctt tgatacccgt ccacctgttc aagagagaat ggagtgaggg gatgaaaaag
    94921 aaactttttc ggattgtggg aatcgttttt attagcatac tcactctgat agttctattg
    94981 agtttagttg gtacggtagc cgaggcgaca gggctagttg atgatacagt tgaagcagga
    95041 aatctatatt ccaaatattc actgaacaac tatcaactag atttctttgt ggatagctct
    95101 tgggattggt tgccttggaa ttggggtgat ggcttaggga aaagcgtgat gtatggtctt
    95161 tatgccatta ctaatttcat ttggacggtg agtttgtatt tgtcgaacgc cacgggttat
    95221 gtggttcaag aggcttacaa attagatttc atttcggata cggctgaaag tattggaaag
    95281 aatatccaaa cattggctgg tattactgaa aatggactcc agacctccgg attttatttt
    95341 gggtttctat tattgatgat tttagctctg ggggtgtatg tggcgtatac cggattatta
    95401 aaacgagaaa ccacgaaagc agttcgagcc gtgattaatt ttgtgatgat ttttctacta
    95461 tcgggttcgt tcattgctta tgcgcctacc tatatcacaa aaatcaatga ctttagctca
    95521 gatgttagtg aagcggccct tacccttgga accgagatcg ttgtacccaa ttcagaaagc
    95581 caaggaaaag atagtgtgga tttgattcgg gatagtttgt tttcgattca agtccaacaa
    95641 ccttggttac tactgcaatt tgatgattcc aacatagaag aaattggtga agaccgggtc
    95701 aacaagattc tatctgtgag tccagatgaa aacaaaggca aagatcggga agaagcggtc
    95761 aaggcagaga ttgaagacaa tgacaatgcg aatctcagta ttaccaagac catgaaccgt
    95821 ttagggaccg tggtcttttt ggtattgttc aatattggca tttccttctt tgtttttctt
    95881 ctaacaggga ttatgttgtt ctcgcaaatt ctcttcatta tctttgcgat gtttctgcca
    95941 attagtttct tattgtccat gttgccgact tatgaaagtt taggaaagaa ggcgattatt
    96001 cgtttattca atacgattat gatgcgagcg ggtgttactt tggtgattac gactgcattt
    96061 agcatctcca cgatgttttt caatatttcg gcaacctatc catttttcat ggttgctttt
    96121 ctgcaaattg tgacctttgc cggtatctat ttcaaattgg gcgacattat gagtatgttc
    96181 aacctccaga gtaatgatag ccagtcaatg ggaagacgcg tcatgcgaaa accgcaaatg
    96241 ttaatgaatc gaaaattgcg gcaactcaat cgaaatgtgg gacgagcttt ggcttttggt
    96301 ggtggtgcag cagtcggaaa taagttggca aaggaacaat caaaatccaa atttaagcca
    96361 tccggttctt ctctacgaaa gaattcacga ttaccgaacg atcacgaaat actatctgac
    96421 ttaactaagg agaatccagt ttcaaataat aagaaacaat cccgaatgaa tttggctggg
    96481 agaaaaatcg gcaaagtttt ggatacccaa gctttggtga aagataagac taaacaagta
    96541 aaggatcagg taaggaatac gccaacgaat ttgaaataca atctccataa aggaatcgaa
    96601 aagtcgaaaa aagcaccaga agaattcaag cgcggactgt tccaagaaaa agcggatcga
    96661 gtggatttgc gagaaaaaca acgacaacga agaaatgcga aaatggacga aaaacgcaag
    96721 atactgagtg aagcaacaaa tcgtcaggga aaaagaaggg cgaatattcc aatagataaa
    96781 gcagctcaac ctcagaaaga tatgatgctg aaaaaagaag caccaaagcg gattgtgaga
    96841 gcaaatctga atcccgaaat caaacgaaaa ctaactagtc aagaaatcat ttcaaaaggg
    96901 aaaagccaat cagcaagtaa gaaaaattct ttccaacaag tgaaacagag gtccactctg
    96961 ccaaagcaga ccaatcaaaa agtacaaaaa agaatgaacc atcgtccaaa atcaaggtca
    97021 ggtgagaaaa aatgaacttg aagaaagtgg gtgttatttc attaactttt ctgaccatct
    97081 cttttatggg tattttgatg tgtgtgggtt tgttgtttgg tgaagacagt gagggaaatg
    97141 gtagttctgg cacttctcct ggcggaacta gtgtctcaga agaagtattg aaacaccgtg
    97201 caatggtgga aaagtatgcc aaagaatcgg atataacaga gtatattcca attcttttgg
    97261 cgattattca agtggaatct ggtggcacaa tggaagacgt tatgcaaagt tctgagtcag
    97321 ccggattacc acctaattca ttaagtaccg aggcatccat caaacaaggc tgtctctatt
    97381 ttgcgtcttt ggttaagcgt tccaaagaac tagggtgtga tcaagatagt attattcagg
    97441 cctataacta tggtggcggg tatctagatc atgtcgggaa aaacgggaag aagcatagtt
    97501 ttgctttagc tgaatctttt tcaaaggaaa aatcaggtgg tcaaaaagtc gattacccca
    97561 acccaatcgc gattaaggaa aatggtgggt ggcggtataa ttatggcaat atgttttact
    97621 gtttattagt gaagcaatac ctaactacaa ctcagtttga tgacaaaata gtccaagaaa
    97681 tttttgatga ggcatttaag tatgaaggaa cggcctatgt gtttggtggc tcaagtccag
    97741 aaacggggtt tgattgtagt ggcttgaccc aatggtgtta tgccaaagtt gacctgaaac
    97801 ttcctcgggt ggctcaggat caatatgatg ccatgactca tattgatcta aaagatgcca
    97861 aaccaggtga tttagttttc tttcattcaa cctatgatgc cggtacttat gtgacccatg
    97921 tgggcattta cgcaggggag aatcgcatgt ttcatgcagg agatccagtg gggtggacga
    97981 atctaacgga aaactattgg cggcagcatc ttatcggagc tggccgatac aaataagaga
    98041 aaagaggaaa aagaatgaag ataaaaattg aacggaatca aaaggaaaag agcccaaaaa
    98101 agaaaaaaga acgagttgta tccgtgggta agcatcgaaa aatggtgctt gccctttggc
    98161 ttttattgtc ttgtagtctt gcttttggcg tttataaaaa tttcaccgcc attgatcaac
    98221 atacaactca tgaaaaagtg gttataaaag agaaggtagt gaatacttct ggcgttgaaa
    98281 gttttacaga ggattttgcg aaagaatatt tttcatggaa aaataacaaa gaagcaattg
    98341 aaaagagaat gagtaatctc gaacagtacc ttacagaaaa cggtctcgct ttaatccaag
    98401 atatggttcg agcagatatt cccacgagtt ccgaagttca atctgtaaaa attctagatg
    98461 ttgaaaaaca ctcggaagaa tttgtcgttt catttttagt ggagcaacat attacagagg
    98521 gaaaaaagac gcaatcaatt tcttctgcat atcgagtgac aatctttgaa gatgaaaaca
    98581 ggaatcattt agtaactagt ttgccaacaa tgattggaaa gccagacaag gcaaaatatg
    98641 aagcaaaaca agtagaaaac gattcagaaa ttgatgccaa aacaacggaa gaaatcaccg
    98701 attttttaga aacatttttt aaactttatc catcagcttc tgaaaaagaa ttggagtatt
    98761 atgttgaaaa tggtgcgatg cgaccaatca atattgactt aaagttttcg gagttagaga
    98821 atccagttta tctacaaaac ggaaaaaatt ttctagtgag tacaaagata aaataccttg
    98881 ataatgtatc aaaaaccact agctactttc agtacaaatt agtattacaa aaaaatggaa
    98941 actggaaaat cgttgatgtt aaataataat gactcaatct aattttatta gaagttataa
    99001 gtagtgtaac ttatttcagg cagaagtcgc ccatcctcta taggtgggtg atgaatgcca
    99061 ttcggtaact cgaaaaccga caattaagac atagtgcctt tttattttaa tccatgtcat
    99121 aatcagtcta tataggaaat ggttgatata ccatggaatt agatacaaat aatcattcag
    99181 tttttcttct tggttacccc cttattttag tagtgaaaca ttgtaaacat gtcattgatg
    99241 atgtaatgtc agcttatgca aaaactgcct ttgaaagaat ttcagaatca catcacatta
    99301 ccttagatga atgaaatcgt gataaagaat actttcatat tatgctcaaa gcacaaccta
    99361 aaaccgaatt aacaaaattc agcaatgcct aagctcacgt ctgataaaat gagactttct
    99421 aagggtcaaa aatttccttt gaatacgatt attgcttaga taaaagtaaa agccttagaa
    99481 ctacggggat agcttggtta ataagagata tcgttgttag taaagacata ggcttgcaag
    99541 tatgctctat tcccaagaat ctcccccttc aagcaccaag gatcgttaaa ttcagctaag
    99601 tggcaagtaa ttcactagac gataattatc tccatatttc aatctcagct tttccatttt
    99661 tcatagcaaa ttccgttatt tttatagcat ctaaaagatt cagcttttcc actgatcttt
    99721 caccactttt cagctttttt attgtgctta aattgatacc agtacctttt gatattgaat
    99781 tggaagtaaa atcattaagg gtttttttta ttaaattcat atccgcaatt ccagcgttca
    99841 taagaatgaa gattctcctc tcatagacta ctttgaaaat ggtactacag tggctgttta
    99901 tatatttcag taggttactg tagtggtcat cttattataa ttagaaaagg aacctaaatc
    99961 aaaaatgcta aagaaaattt tcatagtatt aagcctctca tgactaaagc cacggaattc
   100021 ttgataaaag agtatacttg caagcctaaa cagcggtatc tcttattaac caagctatcc
   100081 ccgttgttcc taaggttctt gatgttttct aaggcaatgc ttgtattcat agcccttggt
   100141 caaaatattg atactatcgt tgacgtttcg attatgatgt atacggcaaa taggacaagt
   100201 ccattctcga attgtgagtg acttcttacc atctgtgtgt ctacattctg aaccaatttg
   100261 actagacgga aatcatttat ctatcttaat gattttttga cagaagtatc gaaaatcttt
   100321 acataatctg ggtgatgtat tcttatgcag atgagagcgt tggctccgta ttcataacca
   100381 gtagcctcta aaacgtagtc catcggtggg atacctagct tgcggttgcc agcggctttc
   100441 gcagtcttct tgtgatcaaa tcaagcatct cattgagcac tagtattttg aagataatac
   100501 ttgagttttt cggcttttag aagttcactt catcttccat catccatgga aatcccactc
   100561 acccatacgc aggcctccaa aaattcttca acagtggttt tttcagacat ttttctgaat
   100621 acctccttgt tttttgatac gccagatagt caggaaaaag gcaacaaaac acaaaacaaa
   100681 gctgcctaaa aaggtaatct tcattccata taaaaagaca tccggccgat ttgcgatata
   100741 gttagttact tgctggccca tcttagcaga catcgcttga tataagaccg tcgtagaaag
   100801 cgaaatcccg ctgaccatcc ccaaatttcg ggcaaaggaa ttcatcgagc ctgccagtcc
   100861 caagttttcg atagtgaccg agctcataac catcgtatta ttgggggact ggaacaaggc
   100921 attgccggca cccatgatgg cagtagcgac aatgtatagc cacaaaggag agtccactga
   100981 caaaaacata tacatgacct gggttaccga caataagccc aagcctacta ataccaaaat
   101041 ctccgggcca acccggtcgg tcaggtagcc gcttaaaggc gccccgacga ccatcatcaa
   101101 aggaaagacc atcatcaaca gcccagcata gctaggactc aacccgcgag cattttgcag
   101161 ataaaaagga atcactacat tgacaaagaa gttggaagaa aaaatcaaca aggctgtaat
   101221 caagctcatg gtaaaaatct tgttcttaaa aataccgaaa gaaatcaatg gagaggctgc
   101281 tttcttttca acttttaaaa agctgacaaa ggcaatcact gaaattacga acagtacaag
   101341 ggggactgga tggaaaaagc cactttcttg ccccaaaaag attgctccaa aaaagctgat
   101401 aatcgtagcc gcaatggcag caaagccccc tccatcgatt gtatggccgc tcatggtgat
   101461 atcttttggt aagaattttt cagcaatcaa catcgttacg attcccaccg gtacattgat
   101521 ccaaaaaatg tacgcccaag aaaattggga caaaatcaag ccgccaagac ctggtccagc
   101581 aatcgagcct aatgaaacaa acgcacctat tgctcccaat gcccgaccac gttcatgtat
   101641 gggaaagact tccgtgatga ttccggcatt tgtagccata gtcatactag caccaatggc
   101701 ttgtaccacc cgtgcgaaca ataaaatacc tagcgaatga ttgaacccac acaacagcga
   101761 tcccaagaca aagatcagcg taccaatccg aaatactttg attttcccac ggctatcgcc
   101821 aattttacca aacagcaaca aacaagaaca gacaatcatc agataaacgg acactaccca
   101881 ttccgcttga ttcattggta tgcccatatc atctgagatg gtaggtagtg caatattgac
   101941 aatactgcca tccaatgtgg acatgaaggt aaacatagat atagcaatca aaatccacca
   102001 gcgatttttt tggacttttg catcttcttg ataactatac ataataggat ttcctttcta
   102061 atgatcgtgt agctaagaac aatataacct atgtctactg cccaacaact tctcgcgact
   102121 ctagccatag gaagcttgag taatttcgat ttgatatcct catgtaacca tgtaagttgg
   102181 agatgcttta tttgaactta ctctatagta actagtgata attcgcttta ctttcttcta
   102241 gcaatttcta aaagtcgact tcattgttct tcagattaat agtgtgagct atctcgtgag
   102301 acgtaagcaa atttccattc tactttttcc caattttttc atatttatgg tgttgcacct
   102361 atttgttttc caatttgctt ttcaaataca ttgctatgat attcaattcc ataggattat
   102421 actaaatatc aatagtatga ataatatatt atagatgttt atatatcact gttaattatt
   102481 atccacaata attaatgatt acctcgatat ttgtcaatca aaggttgaaa caatttattt
   102541 tcagcatctt ttctagcttg agctgcactc ttaatagaat catacgatcc taaatagtac
   102601 ctcttttttt ttaaagttat atacgcaatc tatttctctt tagaacgata aactccctta
   102661 acaccacttg tattattttt cggtaatttt gacgttagac actctattac tgtcccttca
   102721 acacatgtcc ttgtttcttg cctttttaaa catccacaac tttgagtatg tccaaaaaat
   102781 aagttactat aacttatctc acacatactg ccacactcac aatgacaaac ccattttgtt
   102841 ttccatgaac agttattgtc caaaggatac tttgcagtaa gtaatccgaa ttttttattt
   102901 tcaatgtgat gcttttttga tttcaaacat ccacagcttt ttacatcacc ttttagaagt
   102961 cgctttgccg atactaactt ttttctccca cacagacatt gacattccca aacaacagtt
   103021 ccttcacttc gcagtttagt tggcttgatt gcaactaact taccaaaagt tttatttgtc
   103081 aaatttttat atttatgcct atttttataa tttccacatc cacaactttt ggttctacct
   103141 gttagtaagt ttgatcgata tacaatcgtt tcattcccac agtcacatag gcaacgatat
   103201 tttttatatc cattatgagt aatctcctca acaacagtaa ggtgaccata tctttccttc
   103261 actgcaccta ccctcccaag aaagaagtac catataattt caattaactt ttaataaatc
   103321 agaaaaaaat atttccaatt tttcttagtc tgattttatg actaatttac aatacaagac
   103381 tgaacgatac gtacacgaaa tcctcaagat agataaattg ttttcatcta gtgaaacctg
   103441 ctcaaaatat gagcataaag acggcaataa tacactcgat attcgataat ggacttgttt
   103501 tatttgtcaa acccatcgta atcgagatat caattccagt ctcaatatcc tgatcaaagg
   103561 tctaagaatc caaccatttt cttgttactt tgtcagattg attacctttt ttagtctccg
   103621 aataataagg ttttcggatc aactaacatg ctctgagaaa gactactatc tttgcaaatt
   103681 tccaaatgaa ggtgtgggcc agtactattc ccagtacttc ctacatagcc aattatttgt
   103741 ccttgcaaaa cattatctcc agtttttact aggtattgtt gctggtgagc atataacgcg
   103801 gttgatccat cttcgtgttg tatcaccacg taatttcccc aagagtagtg aaactctgct
   103861 ttaacaacct taccagcttt aactgcatga atcggctcac cctgtgtagc tgccatatca
   103921 agtcctcggt gaaattcatt tccacgattt ccaaacaaac tggttattga ataattatga
   103981 ataggcactt ggtatccagt cttactcatt tgtggacctt taacttcttt atcatagttg
   104041 gttaaatcgt aggttttaat taattcattt agcttcaaat agtattgtgt atctgttgca
   104101 taccgtcctg taaggaattt agttgcttct cgatatgttt tactattagc ttttaatgct
   104161 cctgcataaa aatctttatt tccactaatt cccttagtta ataatttggc ataatcttca
   104221 aagctttcct catagttttc atacactcta aattttgatt gggtcgtata aagcgttcca
   104281 ttacccaaat cttcgtttgt taccataatg acaaagtttc cattataagt tccttttatc
   104341 ccaaataaat tgtaattcgg tgcctgagct aactggcttt gaccactggc agattctaag
   104401 atcgcttgtg caatcataac agaagcatat aaatcatatt tctgaccaat ttttctcgca
   104461 gactcaccaa ttttcataat aaaattttct acagattcat ttttgtcaaa atgaatttct
   104521 tcattaccag atagtattgg ttgtgattgg aaagattctg ttgattctat ttgctgtggt
   104581 gtcgaaaaag tttttgtttg tccttccgtt tttggcgctt ccttttttga agattctata
   104641 tggtttggtt ttgtcacttt cgaagaagtt atttcacttg tactacttga agttgttgaa
   104701 gattcggtac ttgaaatcgt actactttca cttgacgaag ttgttgaaga ctcggcattt
   104761 gaagtcgtac tactttcact tgatgaagtt gttgaagact cggcatttga agtcgtacta
   104821 ctttcacttg atgaagttgt tgaagactcg gcatttgaag tcgtactact ttcacttgat
   104881 gaagttgtca aaagttcact actctctgct gttacatcgg aattactcat ttcagtcgtc
   104941 tcggttcttt cttttgcaat tttgtatgtt gaattttcgc ttgccaacac atggaaaggt
   105001 gttgctataa ggagttggga cattaatata actgctgatg caagttttaa agattttttc
   105061 atttgattta cctctctttt ttctctttaa tagtgttttc tattaaaaat tatgataaat
   105121 attttcaatg aattgagtaa tacagtatat ttcttgattt catttagtaa cgattatgtt
   105181 tcaatgttta atcctgttac tgcctttaaa
//
LOCUS       DAXLPQ010000004        94097 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.004, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000004 DAXLPQ010000000
VERSION     DAXLPQ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 94097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.004"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(29..727)
                     /locus_tag="ACF3UO_000355"
     CDS             complement(29..727)
                     /locus_tag="ACF3UO_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFD3656412.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(720..2072)
                     /locus_tag="ACF3UO_000356"
     CDS             complement(720..2072)
                     /locus_tag="ACF3UO_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFD3656413.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2295..3695)
                     /locus_tag="ACF3UO_000357"
     CDS             complement(2295..3695)
                     /locus_tag="ACF3UO_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFD3656414.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3856..4593
                     /locus_tag="ACF3UO_000358"
     CDS             3856..4593
                     /locus_tag="ACF3UO_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFD3656415.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4718..5197
                     /locus_tag="ACF3UO_000359"
     CDS             4718..5197
                     /locus_tag="ACF3UO_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFD3656416.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5194..5961
                     /locus_tag="ACF3UO_000360"
     CDS             5194..5961
                     /locus_tag="ACF3UO_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFD3656417.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6191..6760
                     /gene="lepB"
                     /locus_tag="ACF3UO_000361"
     CDS             6191..6760
                     /gene="lepB"
                     /locus_tag="ACF3UO_000361"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3656418.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6864..7466)
                     /locus_tag="ACF3UO_000362"
     CDS             complement(6864..7466)
                     /locus_tag="ACF3UO_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFD3656419.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7572..7802
                     /locus_tag="ACF3UO_000363"
     CDS             7572..7802
                     /locus_tag="ACF3UO_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656420.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7793..8041
                     /locus_tag="ACF3UO_000364"
     CDS             7793..8041
                     /locus_tag="ACF3UO_000364"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3656421.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8147..8731
                     /locus_tag="ACF3UO_000365"
     CDS             8147..8731
                     /locus_tag="ACF3UO_000365"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFD3656422.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8734..9807
                     /gene="prfA"
                     /locus_tag="ACF3UO_000366"
     CDS             8734..9807
                     /gene="prfA"
                     /locus_tag="ACF3UO_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFD3656423.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9800..10639
                     /gene="prmC"
                     /locus_tag="ACF3UO_000367"
     CDS             9800..10639
                     /gene="prmC"
                     /locus_tag="ACF3UO_000367"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFD3656424.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10632..10811
                     /locus_tag="ACF3UO_000368"
     CDS             10632..10811
                     /locus_tag="ACF3UO_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656425.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10833..11858
                     /locus_tag="ACF3UO_000369"
     CDS             10833..11858
                     /locus_tag="ACF3UO_000369"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFD3656426.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12033..13277
                     /gene="glyA"
                     /locus_tag="ACF3UO_000370"
     CDS             12033..13277
                     /gene="glyA"
                     /locus_tag="ACF3UO_000370"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFD3656427.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13430..14377
                     /locus_tag="ACF3UO_000371"
     CDS             13430..14377
                     /locus_tag="ACF3UO_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFD3656428.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14511..15140
                     /gene="upp"
                     /locus_tag="ACF3UO_000372"
     CDS             14511..15140
                     /gene="upp"
                     /locus_tag="ACF3UO_000372"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFD3656429.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15279..15521)
                     /locus_tag="ACF3UO_000373"
     CDS             complement(15279..15521)
                     /locus_tag="ACF3UO_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656430.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15642..15714
                     /locus_tag="ACF3UO_000374"
     tRNA            15642..15714
                     /locus_tag="ACF3UO_000374"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15675..15677,aa:Thr,seq:cgt)
     gene            complement(15833..16471)
                     /locus_tag="ACF3UO_000375"
     CDS             complement(15833..16471)
                     /locus_tag="ACF3UO_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFD3656431.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16594..17226)
                     /locus_tag="ACF3UO_000376"
     CDS             complement(16594..17226)
                     /locus_tag="ACF3UO_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFD3656432.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17577..17876
                     /locus_tag="ACF3UO_000377"
     CDS             17577..17876
                     /locus_tag="ACF3UO_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3656433.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18371..20536
                     /gene="acm"
                     /locus_tag="ACF3UO_000378"
     CDS             18371..20536
                     /gene="acm"
                     /locus_tag="ACF3UO_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFD3656434.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20808..21293)
                     /locus_tag="ACF3UO_000379"
     CDS             complement(20808..21293)
                     /locus_tag="ACF3UO_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFD3656435.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    21383..21728
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21773..22414
                     /locus_tag="ACF3UO_000380"
     CDS             21773..22414
                     /locus_tag="ACF3UO_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3656436.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22433..23068
                     /locus_tag="ACF3UO_000381"
     CDS             22433..23068
                     /locus_tag="ACF3UO_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3656437.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23086..23901
                     /locus_tag="ACF3UO_000382"
     CDS             23086..23901
                     /locus_tag="ACF3UO_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3656438.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24220..25656
                     /locus_tag="ACF3UO_000383"
     CDS             24220..25656
                     /locus_tag="ACF3UO_000383"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3656439.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25845..28292
                     /locus_tag="ACF3UO_000384"
     CDS             25845..28292
                     /locus_tag="ACF3UO_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFD3656440.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28522..29589
                     /gene="rlmN"
                     /locus_tag="ACF3UO_000385"
     CDS             28522..29589
                     /gene="rlmN"
                     /locus_tag="ACF3UO_000385"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFD3656441.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            29579..29785
                     /locus_tag="ACF3UO_000386"
     CDS             29579..29785
                     /locus_tag="ACF3UO_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656442.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(29782..30885)
                     /locus_tag="ACF3UO_000387"
     CDS             complement(29782..30885)
                     /locus_tag="ACF3UO_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3656443.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31438..31986
                     /gene="aac(6')"
                     /locus_tag="ACF3UO_000388"
     CDS             31438..31986
                     /gene="aac(6')"
                     /locus_tag="ACF3UO_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFD3656444.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            complement(32234..32353)
                     /locus_tag="ACF3UO_000389"
     CDS             complement(32234..32353)
                     /locus_tag="ACF3UO_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFD3656445.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            32532..34193
                     /locus_tag="ACF3UO_000390"
     CDS             32532..34193
                     /locus_tag="ACF3UO_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3656446.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(34263..34610)
                     /locus_tag="ACF3UO_000391"
     CDS             complement(34263..34610)
                     /locus_tag="ACF3UO_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFD3656447.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            34694..35635
                     /gene="opp3b"
                     /locus_tag="ACF3UO_000392"
     CDS             34694..35635
                     /gene="opp3b"
                     /locus_tag="ACF3UO_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFD3656448.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            35636..36679
                     /locus_tag="ACF3UO_000393"
     CDS             35636..36679
                     /locus_tag="ACF3UO_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3656449.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            36685..37755
                     /locus_tag="ACF3UO_000394"
     CDS             36685..37755
                     /locus_tag="ACF3UO_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656450.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            37745..38698
                     /locus_tag="ACF3UO_000395"
     CDS             37745..38698
                     /locus_tag="ACF3UO_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656451.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            38710..39720
                     /locus_tag="ACF3UO_000396"
     CDS             38710..39720
                     /locus_tag="ACF3UO_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3656452.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(40005..40826)
                     /locus_tag="ACF3UO_000397"
     CDS             complement(40005..40826)
                     /locus_tag="ACF3UO_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD3656453.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(40923..41201)
                     /locus_tag="ACF3UO_000398"
     CDS             complement(40923..41201)
                     /locus_tag="ACF3UO_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656454.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            41469..43478
                     /gene="metG"
                     /locus_tag="ACF3UO_000399"
     CDS             41469..43478
                     /gene="metG"
                     /locus_tag="ACF3UO_000399"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFD3656455.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(43957..44544)
                     /locus_tag="ACF3UO_000400"
     CDS             complement(43957..44544)
                     /locus_tag="ACF3UO_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656456.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            44719..46041
                     /locus_tag="ACF3UO_000401"
     CDS             44719..46041
                     /locus_tag="ACF3UO_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3656457.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            46196..46972
                     /locus_tag="ACF3UO_000402"
     CDS             46196..46972
                     /locus_tag="ACF3UO_000402"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFD3656458.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            46965..47534
                     /gene="rnmV"
                     /locus_tag="ACF3UO_000403"
     CDS             46965..47534
                     /gene="rnmV"
                     /locus_tag="ACF3UO_000403"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFD3656459.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            47527..48411
                     /gene="rsmA"
                     /locus_tag="ACF3UO_000404"
     CDS             47527..48411
                     /gene="rsmA"
                     /locus_tag="ACF3UO_000404"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFD3656460.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            48862..49491
                     /locus_tag="ACF3UO_000405"
     CDS             48862..49491
                     /locus_tag="ACF3UO_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656461.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(49615..50724)
                     /locus_tag="ACF3UO_000406"
     CDS             complement(49615..50724)
                     /locus_tag="ACF3UO_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656462.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            50933..51355
                     /gene="mgsA"
                     /locus_tag="ACF3UO_000407"
     CDS             50933..51355
                     /gene="mgsA"
                     /locus_tag="ACF3UO_000407"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFD3656463.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      51542..51640
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            51678..52214
                     /locus_tag="ACF3UO_000408"
     CDS             51678..52214
                     /locus_tag="ACF3UO_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFD3656464.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(52254..54017)
                     /locus_tag="ACF3UO_000409"
     CDS             complement(52254..54017)
                     /locus_tag="ACF3UO_000409"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656465.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(54020..55735)
                     /locus_tag="ACF3UO_000410"
     CDS             complement(54020..55735)
                     /locus_tag="ACF3UO_000410"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656466.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(56514..56738)
                     /locus_tag="ACF3UO_000411"
     CDS             complement(56514..56738)
                     /locus_tag="ACF3UO_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656467.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            56929..59706
                     /locus_tag="ACF3UO_000412"
     CDS             56929..59706
                     /locus_tag="ACF3UO_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3656468.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            59787..60206
                     /locus_tag="ACF3UO_000413"
     CDS             59787..60206
                     /locus_tag="ACF3UO_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3656469.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            60218..60688
                     /locus_tag="ACF3UO_000414"
     CDS             60218..60688
                     /locus_tag="ACF3UO_000414"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3656470.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            60705..61484
                     /locus_tag="ACF3UO_000415"
     CDS             60705..61484
                     /locus_tag="ACF3UO_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3656471.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            61471..62292
                     /locus_tag="ACF3UO_000416"
     CDS             61471..62292
                     /locus_tag="ACF3UO_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3656472.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            62309..63358
                     /locus_tag="ACF3UO_000417"
     CDS             62309..63358
                     /locus_tag="ACF3UO_000417"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3656473.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            63371..64375
                     /locus_tag="ACF3UO_000418"
     CDS             63371..64375
                     /locus_tag="ACF3UO_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3656474.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            65008..66027
                     /locus_tag="ACF3UO_000419"
     CDS             65008..66027
                     /locus_tag="ACF3UO_000419"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD3656475.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            66070..66951
                     /gene="galU"
                     /locus_tag="ACF3UO_000420"
     CDS             66070..66951
                     /gene="galU"
                     /locus_tag="ACF3UO_000420"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFD3656476.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            67251..67628
                     /locus_tag="ACF3UO_000421"
     CDS             67251..67628
                     /locus_tag="ACF3UO_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656477.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            68234..68848
                     /locus_tag="ACF3UO_000422"
     CDS             68234..68848
                     /locus_tag="ACF3UO_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3656478.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            69621..71360
                     /gene="yfcC"
                     /locus_tag="ACF3UO_000423"
     CDS             69621..71360
                     /gene="yfcC"
                     /locus_tag="ACF3UO_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFD3656479.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            71517..72701
                     /gene="iadA"
                     /locus_tag="ACF3UO_000424"
     CDS             71517..72701
                     /gene="iadA"
                     /locus_tag="ACF3UO_000424"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFD3656480.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            72812..73015
                     /locus_tag="ACF3UO_000425"
     CDS             72812..73015
                     /locus_tag="ACF3UO_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD3656481.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(73116..73778)
                     /locus_tag="ACF3UO_000426"
     CDS             complement(73116..73778)
                     /locus_tag="ACF3UO_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656482.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(73791..75293)
                     /locus_tag="ACF3UO_000427"
     CDS             complement(73791..75293)
                     /locus_tag="ACF3UO_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3656483.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            75841..77520
                     /locus_tag="ACF3UO_000428"
     CDS             75841..77520
                     /locus_tag="ACF3UO_000428"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFD3656484.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            77647..78126
                     /locus_tag="ACF3UO_000429"
     CDS             77647..78126
                     /locus_tag="ACF3UO_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFD3656485.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            78345..79025
                     /locus_tag="ACF3UO_000430"
     CDS             78345..79025
                     /locus_tag="ACF3UO_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFD3656486.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            79033..80364
                     /locus_tag="ACF3UO_000431"
     CDS             79033..80364
                     /locus_tag="ACF3UO_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFD3656487.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            80379..81341
                     /locus_tag="ACF3UO_000432"
     CDS             80379..81341
                     /locus_tag="ACF3UO_000432"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFD3656488.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            81452..81790
                     /locus_tag="ACF3UO_000433"
     CDS             81452..81790
                     /locus_tag="ACF3UO_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFD3656489.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            81869..82576
                     /locus_tag="ACF3UO_000434"
     CDS             81869..82576
                     /locus_tag="ACF3UO_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFD3656490.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(82679..84160)
                     /locus_tag="ACF3UO_000435"
     CDS             complement(82679..84160)
                     /locus_tag="ACF3UO_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656491.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            84469..85005
                     /locus_tag="ACF3UO_000436"
     CDS             84469..85005
                     /locus_tag="ACF3UO_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3656492.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            85083..86453
                     /locus_tag="ACF3UO_000437"
     CDS             85083..86453
                     /locus_tag="ACF3UO_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFD3656493.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            86520..86855
                     /locus_tag="ACF3UO_000438"
     CDS             86520..86855
                     /locus_tag="ACF3UO_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656494.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(86936..87793)
                     /locus_tag="ACF3UO_000439"
     CDS             complement(86936..87793)
                     /locus_tag="ACF3UO_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656495.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            87900..88415
                     /gene="tadA"
                     /locus_tag="ACF3UO_000440"
     CDS             87900..88415
                     /gene="tadA"
                     /locus_tag="ACF3UO_000440"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFD3656496.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            88438..88522
                     /gene="ffs"
                     /locus_tag="ACF3UO_000441"
     ncRNA           88438..88522
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACF3UO_000441"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            88732..90117
                     /locus_tag="ACF3UO_000442"
     CDS             88732..90117
                     /locus_tag="ACF3UO_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFD3656497.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            90154..90831
                     /locus_tag="ACF3UO_000443"
     CDS             90154..90831
                     /locus_tag="ACF3UO_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFD3656498.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            90839..91603
                     /locus_tag="ACF3UO_000444"
     CDS             90839..91603
                     /locus_tag="ACF3UO_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFD3656499.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            91605..92264
                     /locus_tag="ACF3UO_000445"
     CDS             91605..92264
                     /locus_tag="ACF3UO_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFD3656500.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(92294..92803)
                     /locus_tag="ACF3UO_000446"
     CDS             complement(92294..92803)
                     /locus_tag="ACF3UO_000446"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFD3656501.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(92915..93913)
                     /locus_tag="ACF3UO_000447"
     CDS             complement(92915..93913)
                     /locus_tag="ACF3UO_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3656502.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
BASE COUNT        31254 a        16163 c        19337 g        27343 t
ORIGIN      
        1 ttttgtcaca ttcccctttt tcgaataact aggctgtttg tccttcaaga tagggcagat
       61 ccaattcttt accgtaacgt tgttctaaag ctaggcggat caaacgagct gccaggttct
      121 catttcttgc aaggataggt ccatggaaat aagaaccgaa gacatttcgg taaatgacac
      181 cttcagattg gtcttcacca ttatttcctt gaccttgtac cactttcccc aaaggtcgtt
      241 caccttcacc taagaaagtc cgaccattgt ggttttcaaa tccataataa gtttcattga
      301 attcttcgtt atggataacg atatcaccga taaaccggtt attttcctga cttaacgtgt
      361 agtgatccag tgcactgatt ccttggatct tttctccatt agctcccatg tagtagtgac
      421 ctagcaattg gtagccacca caaatggcta acatgacgcc atcattttcg atatagttga
      481 tcaaagaatc tttctttttc tggatgtctt ttgaaatgat taattgctca aagtcttgac
      541 caccgccaaa gaaaaccaag tcatatttat cagcatcaaa aggttcatgt atactaacga
      601 tctccgtatg gcaagaaacc cccatttttt ctgctatata tttcaacatc aaaaggtttc
      661 cgttatcacc atatgtgttc atcaaatttc cataaaggtg ggcgatattg agttcataat
      721 tagccacggt tcattcctcc tttgataaat ccttgagcag ctagttcttt acgaagctgc
      781 aatacagcag tgtaagtagc taaaatatag acatgctcag ttggcaattc tttgattttt
      841 tcgattactt ctggtaattc ttttgtttct gtcaatttat tttctggaat cccggcaact
      901 tttagacgta aagtcatatc tgtatgacgg tctcctccag aaataacagc tgggatatcc
      961 atatcggcaa agttttcaaa attaccatcc caaatccagc tgacatcgat tccgtctgcg
     1021 taattggcat ttaataaagc cactaaagaa aatggataag gagctagacc aatcatatcg
     1081 attacttgat tgatacctac aggatttttg acaagtacta atgtacattt tttcccattg
     1141 atattgatga cttcttgtcg gccgaatact ttctcgtcat atcctaaacc ttgtttgatt
     1201 ttatcaggat cgacattgaa gtactctgcc actgcagtag ctgctaaagc attgtagaca
     1261 ttatacatac cgccaacttc gattccgtat tcatgaccat cgatcacgaa atctgctgac
     1321 acattgtcca tccgtaccat atcagttaat cgataatcca attcaggacg tttgaagtca
     1381 caatttggac agtaatattt ccctaagttt gcataagtga tcattttata atgcaagatg
     1441 tgatgacaat ttggacataa gacaccgtct gtattgtaat gagccatttg ttcacgatct
     1501 tcttcatggt caaagccata atattttcta ggattgactg tttcgataga attgaagatt
     1561 ggtgaatcac cgttactgat aatcgttgca tttggtgact ttgcggcacc gtctacaatc
     1621 attttatagg tcgtatagat ttctccatac cgatccattt gatcacggaa aatatttgta
     1681 aataagaaca gttctggttt catatattct gtgactttgc tcaaacttgc ttcatctatt
     1741 tctaggacag caaacttttt ctgtcctttt tttggttttg cctgcaagaa agtcgataca
     1801 attccctgta ccatattcgc accagtaggg ttggttagaa cttcatcgaa ttgctggcgc
     1861 aaaatattga ctgttaaagc ggtagtcaat gttttaccgt ttgttccggt gacaacgacg
     1921 acttggtagt cttttgccaa actatctagt atatgtggat cgactttcag cgctagttta
     1981 cctggtaaac ttgatccgcc tttaaaaaaa gtttttaatg cccattgcga cgtttttcca
     2041 actgcaatcg caaaatgact gcgtattccc attatgtaac ctccaaaaac gatttgctga
     2101 cgaataaatt caactaatca taccatatgt tgaaaaaaag gttaaattgc ttttcttatt
     2161 cttaagaaaa ggttacggct gaaagtgcat gaaatcggac aaaatcgcat gatttaacaa
     2221 aaaaacagct tgaaacaaaa tgattgtttc aagctgctgt gattttatta ttccctctta
     2281 cctatattcc cattttaacc gataataatt ttctcgcttg gatattcata gcctagatct
     2341 cgtgtttctt ttggcacgaa taacatcaat gtatatagca ttccgatccg cccaataaac
     2401 atcagtgtag caatcgtgat tttgcccaca acagacaagt ctccggtaat ccctaaagat
     2461 aaaccagttg ttccaaacgc agaagttact tcgatgatga tcgagatcag cgtttgttct
     2521 tctgtagcag ataaaaaaac gatacaaaag aaacacatac caagagaaag cataaagaca
     2581 acgactgatt ttcgcacatc atcttgatcg attctccgtc caaaaatatt gatgttatct
     2641 tcacttttga ggaaggaata tagatacaaa ccgatgattg ctacagtagt tgttcgaatc
     2701 ccgccgccta cagaactagg actgcatccg ataaacatca gtaaagaaaa aatgatcagt
     2761 gttgtgattt gaaaatcacc caaatcgtga atctgcagac cagcattacg agtcgtaatc
     2821 gaataaaaca tcgaattgat ccatttgaca ctcatattgg aatcttggaa taaatggtcc
     2881 ttttccaata gataaatcaa gacagttccc gaaacaaaca agataacaaa agctaacaca
     2941 gctaatttgg taaacaagga aaaacgaaac ggaagcttcg cattggaacg tttgtataat
     3001 agccattccc ggcactccat caatacagga aaaccaattc ctccgacaaa aatcaaaaac
     3061 atgatcagga tcaagaaaaa atagtcatgt gcaaagggct tgatggaatc cccagtgacg
     3121 tcaaacccag agttcgtgac agccgatatc gcctgataaa aaccgtaaaa aacggcatca
     3181 cgccaacgat caaaatagcc tctgtaataa aaataaatag aaaagaatgt cccaaaaagt
     3241 aattgaaacc agattaaaat agcaaaagtg atccgaatca gtcggacgat accagacaaa
     3301 cgcggttgat tcatatccgt catgatcagc tgtcgctgtt tcagtgtgat ccgtcgttta
     3361 gaaaaaatga caaaagcagt agaaatcatc atgatcccca aaccaccaac ttgaaataat
     3421 atttccagca gtataatacc gttatcattg aacacagaat tgatatcaaa agtcgatagt
     3481 ccagtcacac tcactgtact gattgccatg aacagcatgt ccacaaaaga aacatggcta
     3541 tctggttcgc gaaaaatcgg catataaaat agaacgagtg ataagaccgt catcaatata
     3601 taataaaaaa cgatgatttg gatcgatgag aaatgattgg cagcaaactt ctgtcctcgc
     3661 cgctgcagcc ttcgaaagaa taaatcaaca tgcacagtac tatcctcctg acaatagtcg
     3721 tttctaccag tatacaaggg gaattaggaa tactcaaaga aattatcaaa cagataacaa
     3781 tacagctttc gattaaaata gaaatggctt ataataagga aaatcctaga aaaaagaagg
     3841 aggaggaata acaaattgat taatgctcaa caaatcgtag aaaaaatgaa aaatcaaaaa
     3901 ataaattatg atacagttct gaaaaaaatg atcatgcaat gggagaaaga agaagtaaag
     3961 cctaagatat taatacatac atgctgtgct ccttgcagta cgcacacatt ggaattcatg
     4021 tctcaatatg cagagatcac gttatttttt tcaaattcga atattcatcc taaaagtgag
     4081 tatttgcgaa gattacatga acaaaaacga tttgtagacc aatttaatga gaaaactgac
     4141 catcatgttg cgctaatcgt tgatgaatac cgtccaaatg aattcaccaa aatggtttta
     4201 acaaaccatc ttgaaaacga aaaagaaggt ggtgctcgct gcagtgcatg cttcaatatg
     4261 cgattagatc ttgttgcgca aaaagcgcaa gaactaggat acgattactt tggaagtgcc
     4321 ctgaccatct cgccaaagaa aaatgcagct ttgatcaatc agatcggaat ggatatccaa
     4381 aagatttacg ggacacaata cttgccaagt gatttcaaga aaaacaaagg ctatgaacgc
     4441 tctttgcaaa tgtgcaaaga gtatgatatt tatcgccaat gttattgtgg ttgcgtgttc
     4501 gctgccaagc agcaaggatg cgatctgaaa gaaatcaatc gggaagcaaa agcttactta
     4561 aaaacatcaa ccgtagtttt tgaggaaaat taaagaaatc tttcggaaaa acgtaagaaa
     4621 aaaataaaga atttatggta gaaataaggt agactgtata atttgtccgt agtaaagtaa
     4681 ggaaacaaga ataaatttca atgaaggaag agataagatg cgaaaagtag cacctatttt
     4741 gaagccaatc gctgtattaa caatctcgac gattgtcgcg actactacag gtattgtgaa
     4801 tagttccagc taccgtgcac caagttcaag ttctagtact gtagaagaaa caacaccaac
     4861 tacttcagtc tcgacatctg aaccaacaac aacggaaagt ttgaatgaaa ccactacgac
     4921 aagtacatgg gacgatacaa caactagttc gtcgtatgat gagacatata caactgacag
     4981 ctcaagcgaa acaagtaata cggtaccaga tggcactcca tcggattcaa ccaatccaag
     5041 tacaagtccg gatacaagtg ctagctccga aacgatacca agcagtacga ctgtagatga
     5101 taacacgcaa aatgatgatg cagcacgtac agcacagcaa aaccaagatt caggaaatac
     5161 ccaaacgtat aaccagcaag caggtgattc tcaatgacat ttttactaga ccttatcaac
     5221 ggggtgcata aattccttgg ctatttagac atcagtccta aatatcttaa ccgtggatat
     5281 acgattttaa gtgtgattcc cacgctttat ttattgagaa ttgtttatgg actttggcaa
     5341 aaccaaaact atcttcaatt tttcttatat ggacttgcat ttctagtgct tgtttatttt
     5401 actgttttaa atgtatttta ttacttttta gataaaaaca cgaaagccga tgtcactcag
     5461 ctttttgtga agtatttacc tgatgaagcg ttcaacatcc agacagaaga atcgatagat
     5521 aatggaaatt cgatcgataa agtgaataca caagaggtca tggtttctta tgacgaagat
     5581 tatcaattga aattagccga gaatatgcgg tatttgattg gaaatggtga gatcaaaaca
     5641 aatgaactcg gtcgcatgga tggatttctg gtcgatagaa atacattgta tccttattac
     5701 tatgtcaaga aaacaggaga gaaagagtat gttctaaata ttggacgaag ctactcggac
     5761 atggaaaaag tagggaccat tcgacttgac tcaacagaag acacattgga acctgtcgga
     5821 ttgttcatcg tcggcggtga ttttgtcaaa gacgggttac gctatcatga gccttatcgt
     5881 ctgaaattga ttgcaaaaaa ggcacagtcg caggaagaac cagtggttta tagtcgtagc
     5941 caaagaagaa gacattcata atgtgatgaa acgccgtgta tcagtggttg cgataaaaac
     6001 gtttattcgg aataaggggg atgtgacacg tcttttgtca cgttcctttt ttatataacg
     6061 agaaagataa gacgaacaca tcacttattc tttcctttca tttataaaca ttgtagaata
     6121 aagaaagtac aacgaagtat tgtgaaaaaa cgtaataaat aacgaggaaa atacaagtag
     6181 gaggtaagct gtgaaagaat ttttgaaaaa ttgggggatt ttgatccttg tattagcggc
     6241 tattttatta gctagagtgt acgtgtttac accagttact gtaaacgggc attcgatgga
     6301 ccctacatta agtgatggac aacgattgat ttcatctaag atctcaaact atgaacgaat
     6361 ggatattatt actacaaagg aaccggggga tgaagaacgg atgattgtta aacggatcat
     6421 cggtatgcct ggagatacag tcaagatgga aaatgaccag ttgaccatta atggcaaaaa
     6481 gtatgatgaa ccttatctgg atgagttcaa aaaagaattt tcagaagata agttacaagg
     6541 agaatatgct tatagctcag gattccaagc acaagcagaa agttcatcca cctttacgag
     6601 tgactttgaa tatactgtgc caaaaggaaa gtatcttgtt ctaggcgata accgcttgat
     6661 ttcaaaagac agccgaatgt ttgggttagt cgacaaagat atgatccaag gaaaagttgt
     6721 tttccgttat tggcctcttt cagaaattaa aatcatgtga tgaaaaaata aaaagaagct
     6781 gtgacatgtt ttttgtcaca gcttcttttt ccgaaaattc cttcttattt cttggagttg
     6841 ctcacttttt ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg
     6901 tttttgttca taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag
     6961 cccgtttttt ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga
     7021 tgactaattt gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa
     7081 atttcataaa gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat
     7141 agaaggatga gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt
     7201 cggacatttt tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct
     7261 gaagcatcgg caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca
     7321 gttccgcctc cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt
     7381 agttcttcgc gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg
     7441 atggaatcaa aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta
     7501 acttattata gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat
     7561 ctagaaagaa tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc
     7621 gagaaatatt actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata
     7681 tcgaggaatc aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct
     7741 ttatcactct ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat
     7801 aaaaaaagac tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta
     7861 cgcagcaaaa cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat
     7921 atatgatcaa actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc
     7981 aaatttatgg gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg
     8041 agcaatagat ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa
     8101 aatcaagtat aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt
     8161 ttttaagtat ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa
     8221 ttatgaagaa caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg
     8281 tttaggcgtt gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga
     8341 aacagacgta tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga
     8401 tgaagcgcaa ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt
     8461 ggatattccg gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg
     8521 atcaaaatat ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt
     8581 ctgccacaaa aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg
     8641 cgatcaagtg caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt
     8701 tcacccatca atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa
     8761 gaccgttatg aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag
     8821 cgttttatgc agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt
     8881 cgttataaag aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg
     8941 gatgatgaaa tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa
     9001 gtcttagaag aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat
     9061 atcatcatgg aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat
     9121 cttttcaata tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa
     9181 gctaacgtta ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac
     9241 gtatattcga aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact
     9301 gaatcgcaag ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa
     9361 gaagtagaga tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt
     9421 gctggcggac agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca
     9481 gggatcgttg ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg
     9541 aaaatcttgc gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat
     9601 gccaatcgaa aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat
     9661 ttcccgcaaa atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag
     9721 attttagcag ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca
     9781 aaactggaag ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc
     9841 ttctttttta gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg
     9901 aaaacaatgg aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga
     9961 acagcggttg atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt
    10021 gctaggatat gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc
    10081 tcgaccagaa acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt
    10141 agaagtgata gatattggga cagggactgg agcaattgct attagtttga aagcagcaag
    10201 aaaaaattgg catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga
    10261 aaatgctcag aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt
    10321 aatggatcag caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg
    10381 ggaactgatg gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa
    10441 cgatggatta gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa
    10501 tggaaagatt tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca
    10561 gcaagcattt ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat
    10621 gatccaagtt tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa
    10681 aaaaacactt atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac
    10741 tattgacaaa tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata
    10801 agaatgtatg aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag
    10861 aattgcaaga ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa
    10921 cagtatacgg attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg
    10981 taaaagggag accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa
    11041 aagagtatgt ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg
    11101 gaccattaac tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag
    11161 gattatccac agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac
    11221 tttccggtgt tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga
    11281 ctgcagatca tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag
    11341 ctacgcgaat tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta
    11401 tgattttacg accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg
    11461 ttgctattga tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat
    11521 acaaacacta ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg
    11581 cagttcaatg ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg
    11641 cggatcaagt gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag
    11701 cggcggctaa aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag
    11761 atttgatttt tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct
    11821 tgaaaaaagc agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc
    11881 ttttagtatg atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt
    11941 aactaatcgt aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa
    12001 aattgtagga aaataaaaag gagctgttgt ttgtggtaga ttacaaaacg tttgaccctg
    12061 atctttgggc tgcgatcgcc aaagaagaag aaagacaaga acataatttg gagctgattg
    12121 cctctgaaaa ctttgtctcc gaagcagtga tggctgcaca aggaagtatc ttgacaaata
    12181 aatacgcaga aggttatcca gggcatcgct attatggtgg gtgtgaattt gtcgatatcg
    12241 ttgaaaattt agcgattgac cgtgcaaaag aattattcgg agcgaaattt gcgaacgtcc
    12301 agcctcactc cggctctcaa gccaacacgg ctgcttatct cgctttggta gaaccagggg
    12361 acacgatctt aggaatggat ctttccgcag gcggacatct aacacatgga tcaccagtca
    12421 acttcagtgg caaaacctat cactttgttg cttacggtgt tgatccgaca acagaagtta
    12481 ttgattataa tgtggtacgt attttagcta gaaaacatca accaaaattg atcgtagcag
    12541 gtgccagtgc ttacggacga acgatcgact ttgcgaaatt cagagaaatc gcagatgaag
    12601 taggcgcaaa actgatggta gatatggcac atatcgcagg attagtagca gcaggacttc
    12661 atcctaatcc agttccttat gcagatatca caacgactac cactcataaa acattgcgtg
    12721 gccctcgagg cggcatgatt ttgacaaacg atgaagcatt agcaaaaaaa ataaatagtg
    12781 cggtatttcc tggtattcaa ggcggccctc tagagcatgt gattgcgggt aaagcagtag
    12841 cattcaaaga agcattagat cctgcattta aagaatatag tgaacaaatc atcgccaatg
    12901 caaaagcaat ggtcaaagtt ttcaatcaag caattggaac cagagtcatt tcaggggcga
    12961 cagataatca tctgatgttg atcgatgttc gcgagttagg tataaatgga aaagaagcag
    13021 agagcatttt ggacagtgtg aatatcactg taaataaaaa ctcgattcct tttgaaacac
    13081 taagtccatt caaaacaagc ggtattcgaa tcggcacgcc agcaatcact actcgcgggt
    13141 tcaaagaaga agatgctgta aaagtggctg aactagttgt caaagcatta caagcaaaag
    13201 atgataacgc tcaactagac gaagtcaaaa caggtgtacg cgaattaact gaaaaatttc
    13261 cgttgcataa aaaataaaaa tttaaattcc attagtaaac agaaaagttc aatgttgggc
    13321 ttttctgttt attttttggg aaaacggatt ctttgacaat atcggtgatg ctctctagta
    13381 tatgaggtgt aattttagtc ttcacactaa atctcaggga ggaaaagtca tgactgatcg
    13441 tatctcgtta gaaaaggaag cagtagcatt cagtgatgca aatgcgcctc atccgcgtat
    13501 ctatgaacta gcaccggaag aaggaagagt tttactagaa gaagtacaag aatcacctgt
    13561 gaacaaatat tccgtcgata ttgaagactt gatggtggat actggcgaat ggggaaaact
    13621 caatattcgt ctcgtacgac cagaagggaa tatggataaa ttaccagtta ttttttatat
    13681 tcatggagca ggctgggttt ttggcagtgc tcaaacccat gataaattga tcagagaact
    13741 tgcggttcgt acgaattccg tcgttgtctt tccagaatat agtcgatcac cagaagcaaa
    13801 atatccaaca gcaattgaac aaaattatgc tgtgttgcaa cagctgaata aattagccaa
    13861 gtcaaaaaat ctggatctcg agaatctaat cgttgcagga gattcagtag gtggtaacat
    13921 ggctacagtc atgacgatct taacaaaaga acgaaagggc ctcccaatat ccaagcaatt
    13981 gctgtattat ccagtcacaa acgctgattt tgatacagat tcctatcatg aattcggaga
    14041 aaactatttt ttgacaagag aaggaatgat gtggttttgg gaccaatata cgacgaatga
    14101 agaagagcgt gctgaaatca cagcttcgcc tttgagagca aatataaatg aactaaatga
    14161 tcttccttca gcaatgattt taacgggaga agcggatgta ttaagagatg aaggtgaggc
    14221 ttatgcgcgc aaacttcgtg atgcaggggt tcctgttaca caagtacgct tccaaggaat
    14281 catccatgat tttgtcatgg taaatgctat ggatcagaca aaggcaacgc gtgcagcaat
    14341 ggcattatct acttcttgga tcaagaaaaa agaataagct ttgcttgtcc gcaggaaaac
    14401 ttcttttcaa aaacggattt tcttaggaaa aatggcgagt ttgactagtc aatcacttga
    14461 ttttgtttta caattaaaaa gaaacgacag aacaaaggag agcttaaaaa atgggcaaat
    14521 ttcaagtgat cgatcatcca ttgattcaac acaaactaac tattattcgg gacaaaaact
    14581 gcggaacaaa ggtttttcgt gaagtagtcg atgaaatcgc tatgttgatg gcatatgaag
    14641 tatcacggga tatgccattg gaagacatcg tgatcgaaac accgatcact gaaacaacac
    14701 aaaaaacgtt gtctggtaaa aaagtagcga ttattccaat cttgcgcgca ggtattggaa
    14761 tggttgacgg tatcttggaa ttgattccag ctgctaaagt gggacatatc ggtctttatc
    14821 gagatgaaga aacattggaa ccacatgaat atttcgtcaa acttccagaa gacattgatg
    14881 cacgtcagtt gtttgtagta gatccaatgt tggcaacagg cggatcagca atcatggcaa
    14941 tcgatgcatt gaaagaacgt ggcgcgtcga acattaaatt tgtttgtttg gtagcagcac
    15001 ctgagggagt aaaagctttg caagaagcgc atcctgatat tgacatctat acagcttctc
    15061 tagatgaaaa attgaatgaa catggttata tcgttcctgg actaggggat gcgggtgacc
    15121 gtttgtttgg tacaaaataa gtaaatacga aaaagggtgt gacacaactt ttgtcacatc
    15181 cttttttggt catttttaac gtttgatgca gaacagcttt ttcacagctt tcgtttgcat
    15241 ataaaaaaac catcccaaaa atgcagagat ggtcaaattc aaatcttttt tagttctttg
    15301 tagttaacga ttactacacc cttactttgc gtcatcaagt tcgcattttc tgcagtttca
    15361 tcaatctcaa caacagcgga atttttcaat tgctttgaaa tcgttccagt ttgcgacttg
    15421 ccgtgaattg tgaacattac gtgagtattg atcttgaatt tttcaccaat ttccgatggt
    15481 acgatagttg tatcaaattt tccaaaagtt gccattttca taaaacctgc ctttcacatc
    15541 aattatacca cgttttatga aaaatatcat gaaattaaac taattttcca tcggactctt
    15601 tacaatcagc caaatagagt atataatttc ttttggataa ggccagctta gctcagttgg
    15661 tagagcaacg cactcgtaac gcgtaggtcg taggttcgat ccctatagct ggcattaaaa
    15721 gagaagacag atatatcaag gatttttaat ccattgatac atctgtcttt ttgtttaaag
    15781 gaaataaagt atgctttctt agcaatagag catgtattat ttctataaaa atttaggaga
    15841 ataaaacgac tagcaatata gctgtgaaat caaatatcac atgaactgcc caacttgtaa
    15901 tgatcgagtt gcttttaatg gcagcttggt tgaataacaa tcttgccacc ccttgtatca
    15961 aaaggatgtg tgctacagtg tgtaaaatat ttccattatc ataagtactg taatggataa
    16021 atccaaagat gattgctgac aagaaactag cgacaggaat gctgaactta ctagaaaaaa
    16081 tagcgagaaa atacactgag aacaattctt ctccaagtat catgataggc aaaataataa
    16141 ataataacgg gctgaaagcc tcatttattg gattgcctgt taaaccccat ttcaaaattt
    16201 gttgcaaaaa taccgagact gcggcactga ttactacatt gataaaaaaa tatttggcta
    16261 tatttttgac aggagcgaca ggtttcgaga acattttttt cgtatctttt ttaccaaaaa
    16321 caagtgtaaa tgctataaat ccagtgatag ttaaagaaaa aatgctaata atggatggcg
    16381 caaatagcaa ccctaacaaa ccgagtacaa cgacaatagt gcccaatatc ccttttttaa
    16441 gttctatttt ttttcctaaa atgttattca tgataataac tcctactatt cagtttttga
    16501 agatagagtc agtatacatg aagagttaaa ataggcaatg tttttttatg gatatttgta
    16561 ttgctaaaaa tttatcttat atattcattt tgattatact acttttattt gtaaaaattt
    16621 tctagcaaaa ccaagtgctt gcaactgatt aagcgtacaa ttttttagat gttccgagcg
    16681 tacttcaatc atttcaaagg agttgctact taaatcgata ttttttaaat cagtatcaaa
    16741 aaagctagca ttttctaaat cattagtaga aaacattatt ttagtgaggg aacagtctac
    16801 aaaatctgcg cttgataaga cagagtgctc aaaggtactt tcttttatgt ttgaaccaga
    16861 taaatttaca tagtccattt tacaattctc gaataacgtg ttcccaatat aactttccat
    16921 caatttagta cctgttaatt tacaattgac aaatttcacg cgatgcaaca tgctttttgt
    16981 caatatacag cctgaaaaat cacagttttc gaatatacag tcggtaatct ccattctttg
    17041 aaaatcattg gaagcaaaaa atgcatactt gaaaatagat ttgtaaataa ttggatggca
    17101 gattatttgg ttttcgatga cctctttttg tgaaaggata ttatacagtt caaaatcttc
    17161 gttttcatag atatgaaaaa aggatccttt attcaagctt gcttcattaa ctttaggaaa
    17221 aatcatattt aattacctcc attttcataa agtcatatta acaaaagcta aaccaactta
    17281 cattagcaga aaatgagata ggttttcgcc tttttcgata acgatagtgt cgctatctct
    17341 tgaaacgttc ttagaattgc cctgagagac acaaattagg cgtaattcta ataaaaatct
    17401 tagaataaaa atttttactg atttaattta gaatgttttt aaaataaaaa tcgttgccat
    17461 aacagtgtat tgaaaggttt taacaatcca gtaatgattt aaaaaaatct agatgtagcg
    17521 tatactttgt ttatagaatg tagtgggaag aaatatattt ttgggaggaa atcgtgatgt
    17581 ctaaaagtga agaaatagaa aacatggtac taaaattata tgatctcgtt ttaaatccag
    17641 agatcaaaga aaaggaacgt atacttttga tagacgcaaa gacaggctta gaaaaaggtc
    17701 agtattatcc taaagtcata aataatttgg aacgtagttt acgtccgtta gcaatcaggg
    17761 gagaattgtc taaaccagta tcaccgtttt atatggagat atcaacaata ggaaaatttg
    17821 aaaaagaatt aggtcgagga atggcttcgg caccgattac ttttgggcat ttataaaaac
    17881 gagttattca tctcaatgaa ttaaaaagta tagtcaatct cataatgcag gctaggttca
    17941 tttatttgaa cagagtctgt atttttttat tctaaataaa gaaacagatg tttctttata
    18001 ttgtatttta tcctttaatt aacacaaaaa cagctagtat aaactaataa tgttaattaa
    18061 aagtgtattt tatgaaacta tcgttattta ttaatgttgc atttttgtaa gttaaaaatt
    18121 ggaaatatag attgaaaaaa tgaaagcaat aagtaaaata aaatgaatat atgcgaaaaa
    18181 ataatttaca ttaggaaaaa ccttgtaaaa acagtttttt ggcatattta ttttttataa
    18241 atatttgtaa aataactatc aattttttag ttaaaagatt ggaaatgagt gggggaggaa
    18301 ttgaagaaag gatttttgag agatgatata gtaggtttta tttttagtta aaatagggga
    18361 gatagaaaaa atgaaaaagt gtagaaatat tattttatca atgttattta ttattactaa
    18421 tataacatca ctgattcctg ttcatgtcta tgcggatgca ggcagagata tcagcagtaa
    18481 tgtcacttcg ttgaccgtgg acccaacgaa tattacagat ggaggaaaca taaaagtaaa
    18541 attctcgttt gacgaaaaaa aacaaaatat ccaaccaggt gattatcttt ggatcaattg
    18601 gccaagtgaa ggaaatattc gcggtgaagg attccaaaaa gaaatcccat taatgattga
    18661 aaataaaaat gttggaactt taacggtcag aaaagattct gcgcaggttg tgtttaatga
    18721 aaatattaaa aacctagact cagtagaagg ttgggggcaa tttgagatac aggccagaaa
    18781 cgtaaccgat accggtgaag aaaatacggg accattcacc gtgacgagcg gtgataaaac
    18841 agctactgta aatgtgacaa agccagcttc tggttcttct tctagcgttt tttattataa
    18901 aacaggagac atgctacctg aagatactaa gcacattcga tggtttttga atattaacaa
    18961 taacggcact tatgttgaac aaccagttaa aatcagtgat gaaatccaaa gtggacaaag
    19021 attagatcca agtacgtttg aaattaatca aatacactta ggtgaacaga aggtttatag
    19081 aggagaagag ggaatccaac aatttttaca agatttcccc agcgctacat ttaatttttc
    19141 agtaactgat aattacattg aaataactat accaaaaaac tttgtcaatc ttaggaaaat
    19201 aatggtgagt tataagacga tcatagaaaa cccagaacaa ataaattttg agaatcattc
    19261 ggaagcttgg tttaaagaat ttaataaacc tgctgttgat ggagaaagtt tcaatcatac
    19321 agttaaaaat atttcagctt ctggtggagt caacggtaca gttagaggcg aattgaagat
    19381 tttcaaatat atcaatgaca cagagattgg tatcccaaat gtgactttcg aattaagacg
    19441 agcagatgaa cagcctattc aaggacagtc tagtatcctg ttgacttcga atgaacaggg
    19501 agaagctagt atcaaaggcc tgcaagtagg agactatgtt gtaaaagaaa aagaagcacc
    19561 caattggatt gattttgatc cactaagttc aaatgaactc aaattctcca taaacgaaaa
    19621 tgatacagag ggagtcagtt tacctattta taacaagaaa aaggttacga acatcacagc
    19681 aactaaaatt tggaacggtg gaaccactcc aagaccgagt atttatttta aattattcag
    19741 agcaagtaca aacaattggg aaccagttcc tgatgcagaa acaaaacgat tagacaatgg
    19801 aataacttca gtgacttggg aagatatcca acagtatgat gatagtggaa acgaatatac
    19861 gtttaaagtg caagaagtag atcaaaacgg aaatgattat gtcccttcag gttatcaaaa
    19921 aattgaaaac gggctagtcg ttacaaatga gaataaagaa gtcatttcag tctcaggaca
    19981 aaaaacatgg gaagacaatg agaaccaaga cggcaaacga ccgacgacga tcacagtaaa
    20041 tctattagcc gacggtcaac cgatccaaca caaagaagta agtgaaaaag atgattggcg
    20101 ctatcgtttc acaaatctgc caaaatacag agacgggcaa gaaatcatct atactgtaac
    20161 ggaagacaac gtgcccgaat acagtacgac gattgacggg tataacatca aaaacagtta
    20221 tacaccggaa aaaacaaata tatctatacc aggtagccat ataacaccgt ggaaaaattt
    20281 tccagagaag acagagagag agaaaattag aaatctattc tctcaaaaat tgcaaatatt
    20341 tgctcataca ggagaatcca gcgaacaaag aagcaattat attagtaaga gagctgtacc
    20401 taaacagata acaaataaat caaaaagcat tcttcctaaa acaagtagta aaaaatctag
    20461 ttttgctgta atcattggtt tattgatagt aactatctgt gctgggatat tcttacaaaa
    20521 atataaaaaa gtttagttag aatataatat tttttgttaa atatgactga aatcaaaaga
    20581 ataaaattcc gatttataat cgaaaaaaga agcattttta tatatgcttc ttttttcgta
    20641 gaatcaataa atatggattt ggctaactat ggaagaatac tcgtattagt tttcagcgtt
    20701 catactagtt gttacattgt ttgattggcc aaaagaattt ctgatatatt ttgtgctaaa
    20761 taaagaaaaa gacgcttgaa ttgggaaata agaaaactac tctatcatta caaattttca
    20821 taaactggca gatgttctaa gtaaacaagt atcttttcaa agtcggaaaa atccataatc
    20881 aacgtagtgg tattgatatt tggatgaaag cctacggtat cttgacgatc aatagcagca
    20941 tcgatcacga cttggatttt tttctctttg tcgtgcatca atgctaatgg agtcactgta
    21001 cctgctggaa cgcctaggag gtcaggaagc tgttcttcag aaacaaaaga taagcgcttt
    21061 tcttttaatt gttcagctag ttgttttaaa tcggcgtgct tttcatcagg caagatgaca
    21121 agatagattt gttttccttt tcttgatttc aataatagat tttttacttg cggaccaggt
    21181 agggaaaaag ggacattttt gactgacgta atcgcaggat gatcgacttt ttgaaaagag
    21241 atacccagtt tttttagtag ttcataagct tcttgttcgg ttgcacgact catcgcgcat
    21301 caccctcctt tttttattag tgtatcataa aaaagagttg acaaatgaaa aataatcatg
    21361 taaattacac gtaaagttaa aacaaatgac atcgaaaaga agagtagccg ttaggtgttt
    21421 ttagagagtc tctggttggt ggaaagaggc agcagttaac cgtgaaacac atcttggagt
    21481 cgattttctg aagcgtatag taggaaaatc cggggagccc gttacagctg cggtcgttgc
    21541 tagatgacca gataaggctg gcttttccgt gaggagtcgg taaaaaaagg tggaaccacg
    21601 tgattaacgt cctttgatct tcggatcaaa ggactttttg ttttcatctg aacggcaacg
    21661 actgtgtgag gttttttctg caaggaaaaa ataaacagag gtggaaccac gtataatacg
    21721 tcctcttggc atttgccaag aggatttttt tattttaaag gaggaaaaga agatggagta
    21781 tttgattgaa gttatgccgc aattattagt aggagcactc acaacattga aattattttt
    21841 atttaccttg attggctcat taccattagg gattgtttta gcattaggat tgtctttgca
    21901 ttttaagccg ctacgctact tgcttcaaac atatgtatgg gttatgcggg gaacaccgct
    21961 gttgttgcaa ctgattttta ttttttatgg gttgccgacg attgggatcg tttttgatcg
    22021 tttcgaagca gcactcattg cctttatctt aaactatgca gcttattttg cagagatctt
    22081 tcgtggaggg atacaatcga ttcctcaagg tcaatatgaa gcagcgcaag ttttgcaatt
    22141 aagtcccttt caaacggtga cgaaaatcgt catcccacaa gtgacaaaga ttgttttacc
    22201 ttctgtaggg aatgaagtta tcaacttggt caaagattct tccttgatct atatattagg
    22261 tttaggtgac gtaatgcgtg ctgggaaaat cgcgatggaa cgcgacgcga ctttactgcc
    22321 tttgctaggc gtggcaatca tctatcttac attgactggt attctaacaa tcataatgaa
    22381 acaagttgaa ggaaaattaa attattaccg ctaactgata ggaggaagaa atatgattga
    22441 attgaagaaa gtgaacaaag catttggtga aaaaaaaata atcaaagatt tgaatctaat
    22501 cattccagat gggaaaacat tagctatcgt aggtccttcc ggtggcggta aaaccacgct
    22561 tttacgtatc ttggctggct tagaaagttc tgacagcgga gaattttatt tagacggtgt
    22621 accgttcaac ccattcgagc ttaaaatgaa agaacaagtt gtaggagtcg tattccaaga
    22681 cttccagcta tttccacatc tgaatatttt tgaaaacatt accttagcac caaaaatggt
    22741 attgaaacag acaaaagaag aatacaccaa aaaagcagaa gaattagcgg cttcattagg
    22801 gattagtgat ttattgaata tctatcctta tcagctttct ggcggacaaa aacagcgggt
    22861 agcgattgcc agagcattgg ctatgaatcc acgggtattg gcttatgatg aaccaacaag
    22921 tgctttagat cctgaattac gccagcaagt cgagcgtttg atcctatcat tgaaagaaga
    22981 tggggtaacc caaattattg tcacccatga tttagtattt gcagaaaatg tcggtgatca
    23041 attactaaaa gtttccccaa ttcattaaga aaggagaaga tagagatgaa aaaaaccagt
    23101 tttctattcg ctttgatcgc aggtcttctt ctttttgcag gctgttcgaa caaaaaaact
    23161 tcagcagata attgggcgac tatcaacgaa gagaaaaaaa tcgttatagg tttagacgat
    23221 acatttgttc ctatgggatt tagagataaa gacgggaagc tcacaggatt tgatattgat
    23281 ttagccaaag cagtctttga acaatatggg attacggtag actttcagcc cattgactgg
    23341 tcaatgaagg aatttgaact gaacaatgga acgatcgatt tgatatggaa cggctattcc
    23401 aaaacgccgg caagagaaaa gaaagtgcaa tttacaaaac cttatatgga aaacgatcaa
    23461 gtgctgatca cacctaaaga atcaggaatc acaaactttg gacaaatgaa taataagaga
    23521 ttaggtgcgc aaaatgggtc atctggttat gatgtattta cgaaacaacc agaagtatta
    23581 aaagagatag tcaaaaacca agatgctgtt ttgtatgata gttttaatga agcattgatc
    23641 gatctgaaaa gcagacgggt cgatggtctg ctgatggata aagtatacgc agactattat
    23701 ttgaaacaaa gaaacgaact agaagacttc aacataacaa aaggttctta tgagagtgag
    23761 gattttgcag ttggtgcacg caagtcagat agtacattag tgaaaaaaat caatgaagcc
    23821 ctagatcaac tagagaaaac aggtgaattc caaaaaatat ccgataaatg gtttggcgaa
    23881 gatgttacgc cgagaaatta acaaataggg gactgtgaca aaagacgtgt cacagtccct
    23941 ttttccgaat aaacagtgtt ctcctgccaa ctccttgtga ctcggagctg aatggcaggc
    24001 tcacaacctc ttggtaaacg gtgttcaaaa gccagttttt cggtattaag ccaaatttat
    24061 gcaaaaatgt agaaagccat tttcacaaaa tttttcttac tactcgaaac taagcgactt
    24121 tttcacaacc tcctttacat aattttattt tgttgtggaa ggggtttcgt gttattctaa
    24181 aagaggaacg attgaaggtt ataggaaagg aagagatgaa tggaacacaa agaacttacc
    24241 tcatttccaa aagattttct gtggggctct gcttctgcag cgtatcaagt agaaggagct
    24301 tggcaagaag atgggaaagg agaatcagtc tgggatcgat ttgtacggat acctggaaag
    24361 acatttaaag gaacgaacgg tgatttggca gtagaccact atcatcgtta taaagaagat
    24421 attgctttaa tgaaagaaca aggtctgaaa gcttaccgct tctctgtagc ttggacacgg
    24481 atttttccta atggacgagg agaagtcaat caagctgggc tcgcttttta tgagagattg
    24541 atcgacgaat tgattgaaaa cgatattgaa cctatgttga ctttatatca ttgggatctt
    24601 ccacaagcat tgcaagatga atataatggt tgggaatcac gtcagatcat tgaagatttc
    24661 actcattatg cagaaacatt atttgaggca ttccgcggga aagtccatta ctggattagt
    24721 ttgaatgaac aaaatatctt cacttcatta ggttatttgt tagcagcaca tccgccaggt
    24781 gtgacagacc cgaaacgaat gtatgaagtt aaccatattg ctaatttagc aaatgcatct
    24841 gtcatcaata aatttcacga gttagaaatg cctggaaaaa tcggaccaag ctttgcgtat
    24901 acgccaaatt atccaattga cagtaatcct gaaaatgttc tggctgctga aaatgcagaa
    24961 gacctgatgg ccaattattg gatggatgtc tatatgtggg gaaaatatcc gattgctgcc
    25021 atgaggttct tagaagaaaa aggatgggca ccaacgattg aagctggcga tgcagaattg
    25081 ctagaatctg ctaaaccaga ttttcttggg atcaattact atcaaacggc gacgaatgca
    25141 ttcaatccat taaacggagt tggtgctgga aaaatgaata cgacaggaaa aaaaggttca
    25201 tcagaagaaa ctggagttcc tggaatgtat aaaaaagttg agaatccatt tgtcgaacga
    25261 acaaattggg actgggagat tgacccagaa ggattaagga tcggactgcg tcgtatcaca
    25321 agccgttacc gcatgccggt actgattacg gaaaatggct taggagagta tgacaagttg
    25381 acagaagata aacaaatcca tgacgactat cgaatcaatt acttacaaag ccacgtcaaa
    25441 gccatcaaag aagcaatttc ggatggagca gaagtcctag gctattgcac ctggtcttat
    25501 acagatttgc ttagctggct gaacggttat caaaagcgat atggatttgt atatgttgat
    25561 caagacgaaa cacaagaagg atctttggaa cgatataaga aagacagtta ttactggtac
    25621 caaaaactga ttgaagaaaa tggagagaac ctttagttca catacttaaa acaagaaggt
    25681 acggctggat atggccgtgc cttttcttga taaaatcatt tagaaattaa gaaaaactgt
    25741 aaaataagct gaaaaatgaa agaaagcgtc agttctttca aacaaaactt tagttccctt
    25801 actttttttt gtataatgaa acttgatgaa atgagggata ataaatggca caaaagaaac
    25861 ggcctactaa aaaaaggaaa aagacgaaaa aaacgaaaaa gcaaaaacag cagcaggaac
    25921 aaatgctgac gattggtgtt gggtttgcct tgattttatt tgctgtcttc ggctttttaa
    25981 aattaggttt tttaggaata ttgattgcaa acggctttcg gatcattgca ggaaatactt
    26041 accaaatcct ctgtctttta ttagccgtat taggattttg gattgtcatt aagaatacag
    26101 agttttcaat tggtaaaaac cgacgctggt ttggcggcat actcttttat ttcggtatct
    26161 tattattgtt acatgcccat ttatttggca aactccatac tggggaacca aatatcatgg
    26221 ggacgacatg ggatttgtta gccagtgata taaaacaaag tcaagtagac aataacgttg
    26281 gtggtgggat gattggagca atcctttatc attttactta cttcttgatt gcacagcctg
    26341 gaagttattt agcagcagtg ctattactgg caggaggagc attcctgttc agtaatctgg
    26401 aaggctatca gctgttaaat ggtatccaat caattggaga acgagtacag gaattattgg
    26461 aaggtgatcc tgccaagcaa gctcgaaagc aagcggcaaa ggaagagaga atgaaacagc
    26521 gcgcagaagc gaaagaagca aggcgcttag ctgcaaaaga agctgcagaa aaagaagctg
    26581 cagaatatga gaagaaaaaa gcggtgagcc agcaaaggga aaatactgct gatgaatggc
    26641 aggaaccaga aaatacagag ccggagcagc taagttttgt tccaatcgac agttttcaag
    26701 aaaatatcca tcctgcgaat ctagagaaac cagtaccaga tacaccaaaa cagaccaata
    26761 cagcagaagg tttttcagat gagttgccag aggatgacgg tacctcatta gaatttgaga
    26821 ttgaagcaga acaggaaaat caagactatg aattaccgac agttgatttg cttgattcta
    26881 taccaactgt ggatcaaagt gatgagtata aaaaaattga aaaaaatatc ggcgtattag
    26941 aacaaacttt ccaaagtttc ggtgtcgatg ccaaggtcgt caaagccagc ttaggaccat
    27001 ccgtcacaaa attcgaagtc cagccggctg taggggtaaa agtaagtaaa attgtgaact
    27061 taacagatga tatcgcgctt gctttagcgg cgaaagatgt ccggatggaa gcaccgattc
    27121 caggtaaatc actgattggt attgaagtac caaatggaaa gatcagtatg gtttccttta
    27181 gagaaatcat cgaagcacaa ccaaaccacc cagataaatt actagaagta cctttaggac
    27241 gtgatgtttc tggacgggta caaacggctg atctttcgaa gatgcctcac ttactcgtgg
    27301 ctggttcgac tggtagtggg aagtcagtag caattaatgg gattatcaca agtatattaa
    27361 tgcgtgctaa gccccatgaa gtaaaactga tgatgatcga tccgaaaatg gttgaattga
    27421 atatgtacaa cggcatacct catctgttga cgccggtcgt gacgaaccct agaaaagcag
    27481 cgcaagcctt acaaaaagta gtacaagaaa tggaagaacg atatgaaaaa ttcgcggcaa
    27541 ccggagtaag aaatatttct ggttacaatg aatttgttca acagaaaaac ttggaaaacg
    27601 gaacgaaaca tccaacctta ccattcatcg tagtgatcgt agatgaatta gctgatttga
    27661 tgatggtagc cagcaatgaa gttgaagatg cgattattcg tttagcgcaa atggctcggg
    27721 cagcggggat tcatatgatc ctagctactc aacgtccaag tgtggatgtt atcacaggaa
    27781 tcatcaaagc aaatgtacct tccagaatgg catttgcggt atcaagcggt acagattctc
    27841 ggacgatcat tgattctaat ggggcagaaa agctcttagg gcgaggagat atgctattct
    27901 tgccaatggg tgagaataaa ccgatccgtg tgcaaggagc attcatttct gaccacgaag
    27961 tagaacgggt cgttcaattt gttacagatc agcaagaagc tcattatgaa gagaaaatga
    28021 tgccgacaga tgaagttgaa acgacaggtg ctccagaaca gccacaagat gagctgtttg
    28081 aagaagcaaa agcacttgtc gttgaaatgc aaacggcaag tatttccctt ctccaaagaa
    28141 gatttcggat cggttacaac cgagcagcac gtttagtaga tgaactggaa gctcatggag
    28201 ttgttggccc gtcagaagga agcaagcctc ggaaagtatt cattgagcag gaagaaacat
    28261 cagaaacgtt gccggacgat aatgacatgt aaaacttgtg tgatgaaggg ttgaaaaacg
    28321 aataaccaat aaaaagacaa ggcatgatga taccaaaaga aaaaatggtt tttttccatc
    28381 ttttctaata cggtatgatg tcttgtcttt ttagtttttg tgagattaaa gttctattcg
    28441 atttatttgt gaagtattgc attaaggaaa tgaatcatgt atagtatgta gcgaaacttt
    28501 gagaaaaaga gggaaaatac tttggaaaaa cagtccattt atggcttgac gaatgaagaa
    28561 ttaatcaatt ggtttataga aaacggcgag aaaaaattcc gagctgccca agtttgggaa
    28621 tggttgtatc aaaaacgtgt aagtaatttc acagaaatga cgaatctatc gaaacaattg
    28681 atcgaaaaat tatcggagca ttttatcatc aatcctctaa aacagatggt cgtccaagaa
    28741 gcttcggatg gtacagtaaa atatttgttt gaactccctg ataaaaacat gattgagact
    28801 gtactgatga gacaagaata tggcttgtca gtttgtgtga cgacacaagt aggatgtaat
    28861 atcggctgta cgttttgtgc aagcgggctg ctcaaaaaga accgtgatct gactgctgga
    28921 gaaattgttg cacagatcat gatggtccaa cattattttg atgagcgcaa tcttggcgaa
    28981 cgcgtttcac atgtcgttgt aatggggatc ggtgagccat ttgataatta cgacaatgta
    29041 atggactttt tgcatatcat caatgatgcc aaaggattgg caattggtgc tcggcacatt
    29101 acagtttcca ctagtggatt agcacacaaa atcaaggaat tcgctaataa cggcttgcaa
    29161 gtcaatctgg ctatttcctt gcacgcgccg aataatgagg tgcgaacatc gatcatgcgg
    29221 atcaaccgaa gtttcccaat tgagaaattg atggaagctg tggatgagta tttagagaaa
    29281 acaaaccgtc gaatcacgtt tgaatatatc atgttgaatc aagtaaatga tagaccagag
    29341 catgcgcaac aattagcaga tctattaaaa gataagaaaa aattagcata tgtcaacttg
    29401 attccatata atccagtcag tgaacatgat caatattctc gcagtccaaa agctgatgta
    29461 ttgagatttt atgatgtatt gaagaaaaac ggcgtaaact gtgtgatacg taaagaacat
    29521 ggtacagata ttgatgcagc ttgcggacaa ttgcgaagca agcaaatgaa aaaaacagtt
    29581 gccaaataat cgtatcctac tcgttttttc aattaccata aaaggagcag ttttcttaat
    29641 taaggaactg ttcaacttaa ataagagaaa agattctata gcgaaagcta taaagctttt
    29701 tttgacaaga aaaaccctca tcaagcaaag aaatgtcctc aatttgatga cagcctgctt
    29761 gatgggggtt ttagcaatta tttaactgat tttcttatat ccttgctggc tttcttgtgt
    29821 agcatgataa gtttctacgt caagaatggc ctgtttaaat ttttctcggg tgatttcata
    29881 aggcacatgt ttaatatcat ttgttgccat ggctttatct aagattgctt ctaaatcggt
    29941 cgtgacattg agattcatgt cggttaacga tactggaagt tggttctttt tcataaacac
    30001 atagatttta tcaaacaaat cgaactgctg atccatcatc aataaggtca gtacaccata
    30061 actgacagat gctccgtgaa ggtatccctc cattttttct agaacagtcg taccgtaata
    30121 gaatgagtgt gccatagcag aattatagtt attgttaact aaaacagaaa ccaatccggt
    30181 agtaacaatg atatccgaaa cgacttgttc aattgcatat gagggacgat cgtcggcact
    30241 atctttcaat gcttgcgtac cataagtcaa gagacgatca atgcacattt ttccgatttg
    30301 gattcctaat ctatccgtgt agcctagatc atcgccacga gcagaaaaag tagattcgac
    30361 ttctttggat aaagcatcgc caatacctgc ccataagtat ttatcaggtg cttcggcaat
    30421 aattgctgta tcaatgaagg tgtgtacagg tggttttgaa ggaaagaaga gtccgtccat
    30481 tacgccttct tcgttataga tgacacatac cgcagtgacg ggcgaacagt tcgaaccaat
    30541 agtgggaaag gtgaagactg gtttagctag tttttcacca atgactttta cagtatcgca
    30601 agcacggcca ccaccgactg caaacaggac gtctgctttt tggacacttt catgctggat
    30661 caactgttca atatttccat aagttgaatt acccccgtac cagagactgg cgacaacctc
    30721 tatttcctgt gtcaaagcta cttttatttt gttttctgcc tttgaaagtg cagtcttccc
    30781 tccaatcagc actacttttg tcccatattc tttgacgatt ccatttgctt tttcatacgc
    30841 atctgttcca atggtataat ttggtaagaa aacactttga ctcatattca tttccttctt
    30901 tcttcgttga aacgggttaa aattttaaag agtgatcgat ctgactgcgg ctgtagatgg
    30961 agtagaggtg aacctaagac aggataagtg atgaataagg tggcatgaac accttgaaat
    31021 catcaataag tatcctaaaa acgaacaagt acaaaaacat tgaaaacgac aataatgaat
    31081 ttttgttcct cttagtattt ctaccgattc cctttgcttt tttgtaatta tctaaaaatt
    31141 ctaaaaatta agattattat atgaaaacag gttttatttg tcaattcata attggttttt
    31201 tttaaagcaa aagataatct atatcatgat gaacaaacag agttttttcc tccaattgat
    31261 ggctttcctg atctttccta ttttgaataa agtgtttctg tataattttt ttattttata
    31321 agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt tttgagcgag
    31381 aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg aagacgtatg
    31441 ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc tgatttactg
    31501 agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga agaaatgatg
    31561 aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg atttattggt
    31621 gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt agaaagctcc
    31681 cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga agtagcttcc
    31741 agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac aacgttaagt
    31801 caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa ccttcgtgaa
    31861 catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt accaaatgca
    31921 aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg accaaattct
    31981 caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga aggaatttac
    32041 gaaaattact tcttgaattt ttgtgaaatt ccaacttatt tccgaagaag ctacttttgg
    32101 aacaccgtgt accagaggtt gtgaaaaagt cgcttagttt cgagtagtaa gaaaaatttt
    32161 gtgaaaatgg ctttctacat ttttgcataa atttggctta ataccgagaa actggctttt
    32221 gaacaccgtt tattcagata agggactgtg acaagacttt tgtcacagtt tctttttgtt
    32281 tattcttttt tatctttgta tggcaataat agacaatata acgaaaatta tttaatggct
    32341 tttggaagac catggaaaac cttgtacaaa gctatttttt ctgaaaaatt ccttgaaacc
    32401 tcacgaaaaa atcattattt tatgaaaaag acaaaaaaaa gtgttgattt tttaataatt
    32461 attcattaaa ctcttaaaca acttcagaaa atattaatta ttctgaaaat tccaataaag
    32521 gggtacgtaa aatgaaaaag aaatttacat ttggtttggt tgcggtatgc ggccttgtac
    32581 ttgctggatg ttatggcggc agttcagcca caagcagtag ttcagcaaaa agcggttcag
    32641 cagatggagg aggcgtattt aacttagtcg tgcctcaaga aatgcctaca gctgacttat
    32701 cagttgcaac agatacaatc agttttacag cattgaataa cgtttatgaa ggaatttacc
    32761 gtcttgatga agacagcaaa ccacagccgg caggagctag cgagttggca gaagtcagtg
    32821 aagacggatt aacttacaaa atcaaattac gagaagacgc aaaatggtca aatggtgatc
    32881 ctgttacagc agcggattac gtttatggct ggcaacgaac agtagaccca gctacagctt
    32941 ctgaatatgc ttacctgtat gcgccagttg aaaatgcaga agacattaca gctggaaaga
    33001 aagataaatc agaactaggg atcaaagcag ttggtgacta tgaattagaa atcaaattga
    33061 cgaaacaaac accatatttc caatatctgc ttgctttccc atcatttttc ccacaaaaac
    33121 aatccgtagt ggaagaaaat ggggatgcct atgcatctgc aagtgataaa gctgtttata
    33181 atggaccatt cacattagaa gattttgatg gaccaggaac agatacagaa tggacttata
    33241 agaaaaatga tcattactgg gacaaagata cagtaaaact ttctgaaatc aaagtcagtg
    33301 tagtaaaaga atcttctact gcattgaact tattcaaaga tggccaagca gatgacgtga
    33361 tcttgtctgg tgagttagca cagcaaaacg caaacgatcc agcttatact tctgttaaag
    33421 aagcgcggac aagctatatc gaattcaatc aacgtgaaaa gaattcacca ttcaacaatg
    33481 tgaacctaag aaaagctatt tcttattcta tcgatcgtga agctttagta aaacaagtac
    33541 taggtgacgg atcagttgtc tctacaggat tgatcccatc agatatggta aaaagtccaa
    33601 caacgaacga agactttgca aaagaagctg gaaaattagt ttcttatgac aaagataaag
    33661 caaaagaata ttgggaaaaa gcgaaaaaag aattgggcgt tgattcttta gaatttgatt
    33721 tgatggcttc tgatgatgat tcatcgaaaa aagtaatcga atatgttcaa aactcaatcc
    33781 aagaaaactt ggatggcgta acagtcaaac caacacctgt tccattctct gtacgtcttg
    33841 accgctcaac ttcgggtgat tttgacgcag tactaggcgg atgggctgct gactatgcag
    33901 acccaagcag ctttactgat ttgtttgtca caggtaattc atacaaccgt ggtcgctgga
    33961 gcaatgcaga atatgacgaa gcagttaaag cagcttcatc aacagacgct ggcgatgaac
    34021 aagcccgttg ggatgatttc caaaaagcaa tcaagatcat ctctgatgat atgggtgtcg
    34081 ttccggtgta ccaaaaagca gaaggtcacc tagtgaatga aaaaatcaaa ggtatcgttc
    34141 accatgcggc aggcgcttca tgggattaca aatggacata cgttgaagaa taatcgttaa
    34201 taccgtgagc atgagaaaaa acgaggctgc ggcaaatgtc gcaacctcgt tctcatattc
    34261 acttatccta acaaagaaaa aagcatgaaa atagcagaaa gagcaattag tattccggca
    34321 atgatcagcc aaaagctgta cataccgtag ctggcagacg agagcgagga aaattctggt
    34381 tttttctttc ggttccttgt tcgtgcaaga tggaccgatc gctgaaaatg atcgaagaaa
    34441 cccgaagaaa agacccataa aaaaccgccg ataatcagaa acggcaatga ccataagaat
    34501 agatcattag ataattgaat gagtgtaaag gaatggttga tgagattttt tattaaaata
    34561 accagaatca gtagaaaagc tactgcgtag gggatagatt tttttttcat ttgattgctc
    34621 ctttattttt ggttcattat ctaataatgt agcgaaacat ctgtcagaag tcaaaagcta
    34681 gggggaaaca ttagtgaata gttatatcaa atatgtatta aaacgtgtct ttttcatgat
    34741 catcacgctt tggttaattg caacaatcac ctttttcttg atgcaattgc tgccgggcac
    34801 gccatatacg aatcaggaac gtttgagtcc tgaaacaatc gagatgctaa ataaacaagt
    34861 cggtttggat aaaccagtta tcgtacaata tgggatttat ctttctaatt tgcttcaagg
    34921 agattttgga atttccttcc aatttaaaaa ccagccagtc gcacatttgt tagctggaag
    34981 aatcggacca tccttgcagt tagggttaca ggcaattatc tttggaacag tcctagggac
    35041 gattttagga acgatctctg ccatgaagca aaatacatgg gcagatacat cttctacact
    35101 cgtagcgata ttaggtcgtt ccattccaaa ctttgtattt gctgttttat tacaatatat
    35161 ctttgcaatc aaattacaag ttttgccaat cgcaaaatgg gatggctttg tgtacacaat
    35221 cttaccaaca attgcgttgg ccatgtcgcc gcttgctgac tctgctcggt ttatccgtac
    35281 ggaaatggtg gaagtactgc atagtgatta tgtggaatta gcaaaagcaa aaggattgag
    35341 ccgttgggaa atcgccttta aacatggtct tcgaaatagt ttgattccat tgatgacttt
    35401 attaggaccg ttagctgtag cattgatgac cggatcactg gtggtagaaa atatctttgc
    35461 tattcctggt atcggggaac aattcgttaa gtcaatcaca acaaatgatt atcctacgat
    35521 catggctgta acgatccttt actcatttat gctgattttt gttattttga tcgtggatct
    35581 attgtacggt ctagttgatc caagaattcg tgtttcagaa gggagccgag gataaatgga
    35641 aatgatacca aagcgttatg aaacagttgc agatatccct gcggatgaat ttcttccatt
    35701 acaaaaaaat accgaagaag aacgtgaaca gattactgca ccttctttga attttatcca
    35761 agattcatgg cgccgtttaa agaaaaacaa agctgccgtt atttcaatgg ttttactatt
    35821 ggtcatcatt ttgatctctg tgatcacaat ctttgtttct cctcatgatc caactgccca
    35881 aaacgtggct tatatcaatt tgcctcctcg tattccggga atcaatatcg atggattgaa
    35941 tggaaaagca atggttggtg gtgaacttgt tgataaatat gctcaagcaa acgtcccttc
    36001 aaacgtaaat ttctttttag gaacagacgg tttgggacgt gatgtattaa gccgcttatt
    36061 tatgggaatg agaatctcgt tgctgatcgc atttattgct gcattactag atgtaacgat
    36121 tggtgtagct tacgggttgg tttctggttt gttaggcgga cgtgtcgata acgtgatgca
    36181 acgttttttg gaaatcttat caggaattcc aaacctcgtt gtcatgattt tgatgttggt
    36241 cgtttttgaa ccaggaattt tttcaatcgt ggctgctatg gccatcacaa actggatacc
    36301 aatggcacgt atcgttcgtg cacaaacaat gaaattaaaa gatcaagaat atgttttagc
    36361 tggattgaca ttaggtgaat caagaatgaa aattgcattc aaacatattt tgccgaatat
    36421 ctctagtgtc attattattc aaatgatgtt tagtattcca tctgctattt tcttcgaagc
    36481 ctttttaagc tttatcggtt taggtcttac gcctccgtca gcttcattag gaacgatgtt
    36541 gagcgaaggg tacaagacat tcctgtatct gccttatcta ttatggattc cggcagtaac
    36601 tttatcggtt atcatgattg gctttaactt acttgctgat ggattgcgtg atgcctttga
    36661 tcctaaaatg aaagagtgaa gacgatgacg aaaattttag aagtgaaaga cttagaaatc
    36721 tcttttgata cgtatgctgg aaaggtacga gcgattcgcg gtgtcaattt tcatttgaat
    36781 aaaggagaaa cattggcgat cgttggggaa tctggaagtg gaaaatcagt gacgaccaga
    36841 agcatcatgc gcttgctgtc aagcaacgcc aatatagatg ctggtcaaat cctctttaaa
    36901 ggtaacgata tcgttggaaa atcagaaaga gagatgcaaa aaatccgtgg taaagaaata
    36961 gcgatgattt tccaagatcc aatgacctct ttagatccga cgatgcccat tgggaagcaa
    37021 gtcgctgagt cccttagaaa gcataataaa gtttcaaaaa aagagggaca aaaagctgca
    37081 ttagaattgc ttaaattagt tggaataccc gaagctgaga aacgtatcaa cagttatccg
    37141 catcagttct caggaggtca gcgtcaacgg atcgtgatcg cgattgcact ggtatgttat
    37201 ccggaaatcc tgattgctga tgaacctaca acagcgcttg atgtgactat tcaagcacag
    37261 attttggagc tgctgaaaga aattcagaca aaaatcgata catcaattat ctttatcact
    37321 catgaccttg gtgtagtagc gaatgtcgct gatcgtgtcg ctgtcatgta tggaggaaga
    37381 atcgttgaag ttggaacatc ggaagaaatt ttctacaacc cgcaacatcc ctatacttgg
    37441 ggactgcttg gttcaatgcc gacattagat agtgcgaacg atcgattgta tgctattcct
    37501 ggttctccac cggatttatt gaacccgcca aaaggagacg cattctatcc aagaaatgaa
    37561 ttcgcgatga aaatcgatgc agaacaagaa ccaccatttt ttgaactatc aaaaacacac
    37621 aaggcagcaa cttggctact tgctccgcag gcacccaaag tgacaccgcc agaagaaatc
    37681 caacgtcgct gggctatctt taaagagaaa caaaaacata cttacggtca aggaggaatt
    37741 gctgatgcca aataaactac ttgaagttaa aggattgaaa cagtatttca atgtaggaaa
    37801 aaagaatgaa gtacatgctg taaatgacat cagctttcac atttatgaag gagaaacatt
    37861 cggtttagtt ggagaatctg gaagcggaaa atccactact ggccgtacga tcattcgctt
    37921 gaatgaacct actgatggtg agatattatt cgacggtcaa gatataacga agatcaaaga
    37981 taaaaaaggt ttgacgaaat tccggcatga tgttcagatg atctttcaag atccatacgc
    38041 ttcgttgaat cctcgtatga aagtcagaga tatcattgcc gaaggaattg atgttaatgg
    38101 actagctaaa tcatctgaag agcgtgcaaa aaaagtcgat gatctattga gaactgttgg
    38161 attgaatcca agccacggta ctcgttatcc tcatgaattt tcaggtgggc aacgccagcg
    38221 tattggtatt gcacgagcat tggcagtaaa accgcgtttt atcatttgtg atgaaccaat
    38281 ttctgcacta gatgtgtcga tccaagccca agtggtcaat ttgttgcaag atctccaaaa
    38341 agaacatcaa ttgacctatc tatttattgc acatgatttg tcgatggtta aacatattag
    38401 tgaccgaatc ggtgtaatgc ataacggctt gttattagag atgggaacaa gtgatgaaat
    38461 ctataatcac ggtgttcatc cttatacaga aagtttgtta tctgctattc ctctaccaga
    38521 tccagaccat gagagaaaac gcagaagaat caaatatcaa cctgaaccag atgacggaca
    38581 agtacgtcaa cttcgtgaaa tcgcaccaga acattttgtc tatgcaactg agcaggaagt
    38641 cccatattac gcaaaaaaac taaaacgaca aaaggaatct cttctggttg ctaactagga
    38701 gggacataga tgctaaaagc ttttaaattc cgtatgtatc cgacagaaga acaaaaacag
    38761 caattgattc gtacttttgg atgtgctcga tttacctata accatttgct gaaaaagcgg
    38821 cagaaaagtt ggcaacaaac aggagtagcc aatttttcgc tcacacccgc tacattaaaa
    38881 aaagaatacc cattcttaaa agaagtagac agtcttgctt tagcaaatgc acagcttaat
    38941 ttggatcggg cttttcgcaa ttatttcaag ggacgtgcca gcttcccaaa gcttaaaacg
    39001 aaaaaaagta tgtggcaatc ttatacgacc aacaaccaaa cccgtacgat ctatctggaa
    39061 aatggctact taaagttacc aaaacaaaaa gaactaatca agataaatca gcatcggcca
    39121 gttgaaggat cgattcgctc cgctacgatt tctgctcgat ataatgaaga attttatgtc
    39181 gcactacttt gtgatgtttc gccagtaaaa aaagaatctt tagctaaatg gatcgggatc
    39241 gcctatcatc cgaagacatt gatccaaaca tctcgacctc tagaagtaac tttaccaaaa
    39301 tttcaccaga cagaagaaaa gctgcaacat gcacagcgga aattgaatgt gaaagtccgc
    39361 tccgctcacc atagaaagat caggttagat caggcaagca attatcagaa acaaaagaga
    39421 aaagtaatgg atctttatct gaaacaaaag aaccagcgag aagattatct tgaacaatta
    39481 tctgggaaat tggtcaaaca atatgactac ttatttgtag aatcttttcc aaaagaagag
    39541 gcacatgctg atttttctat tcacgactgg cataaattaa taacaaaatt gcgttataag
    39601 tcccaatggt ataataaaaa atttcttttg atcaataccg acggagcaga agaaagcaat
    39661 tccgtaagaa agagccaagt agtagaaaaa atgggcagac attcggttat caagggataa
    39721 aaaatgaatg aaactgatag gagcgttagg gttagccttg ttaataaaaa gtcttaatga
    39781 cttttgtttc taggaatttt tcttttgaag aaaagctcac taattatgac aaaccaataa
    39841 aacaatagca gaaaaagttc gtacgagctt tttctgctat tgttaatttt ttattcagaa
    39901 agtttacgaa tacatcaaaa ttctgaaaca aaaaacgtaa ctcacaaaga gttgtttttg
    39961 cgttttttct tgaatgatta ggtctgaatc ttttgctcac aaccttattc atggtgcccc
    40021 ggcttgagct gatagatttt tgaaggacgg ccgattccta caggacgttc accgatctca
    40081 tcgaaatatt ggagcatagc tttcttaaaa ttggaatgat cgatcgtttt ataatcgatc
    40141 cctaagaatt tagcaaatac ttttcgagct tccgtaatcg tgaaatcttt acctaaaact
    40201 tgtagaactt gcggctcgtg ttccatttta ttgactacac ggttgaatgc tttcaagatg
    40261 atttgactat ggtcaaaagc caaagtatct ttgccagaag actctccagt gactaaatca
    40321 agcgagatag ccacttctcc gctagataaa tggatcttgt tactatgacg ttctagtgtg
    40381 aaccagcgta cttccttggc atcatctccg gcgattagcg gttcttctcc aataaaggct
    40441 aagtagctga ctgtgacgac ccagcctcgc ggatctcgat taggcgtact gaatgtatgc
    40501 agttgctcaa tattttcttt tgaaataacc acaccagttt cttcctttgt ttctcttaag
    40561 acgctttctc cagttgactc atccttttgg acaaagccac caggcaatgc ccatgaattt
    40621 cgataaggat gcccttttct ttggatcaac aaaactttca gctgatcttc ttctttgtta
    40681 tagcacatca gtacgatatc gacagtcaaa gagggcttgt catattctgg acgttcctgt
    40741 ttttgatacc agttaagaaa ttcttcttca cttgctttat gttcataata taatttttct
    40801 tcttctttag aagcaaaacg gttcatctga ccacctccat tgacagtaaa agtacttttt
    40861 accttattgt agcagactct gaaaaaaaac caaggattta cttgaaaaat ctaggttatc
    40921 atttaaatat gaaaaataaa tggaagtatg agattgaata aaaagaaaag cagataaaac
    40981 ggcaatactt tataccgctc ttcacgaatg gcaaagaagc cacaaataac gatatatacg
    41041 tcaatgataa aacgcaaaat ccaagctgct gtcataaaac tgttcaaatg cccatggagg
    41101 ttaaaataac catacatacg aatataaaaa tagctgaata ttaaatgtgc taatgaaaga
    41161 aaagcaatac taagtgtaaa aaaaagatgt ttcttctgca tgattgttcc agtcccttac
    41221 taagatagat agtctttatt ataccacgtg tgaggggaga aataaaaagc cgttttttag
    41281 tagatatgaa acaaaacaaa aacccgcatt tattcaacct attcatcctt ttaaaggata
    41341 gattgaacgt agatagaagt cgtttatcca gtctttttca ttttgaaaaa aagctaacag
    41401 catgcttttt ttatggtata ctagcaagga aacgaattcg catcatgcga taaaggagga
    41461 agagccccgt ggcagaaaag gaaacttttt atatcactac gccaatctat tatccaagcg
    41521 gcaaacttca tatcggcaac tcgtatacta cgattgcatg tgacgcaatt gctcgttata
    41581 aacggttgat gggctttgat gtgttttatc tcactggagt ggatgaacat ggtcaaaaaa
    41641 tcgaaacaaa agcagaagaa ctaggtgtaa aaccgcaaga atatgtagat aaaatggcgg
    41701 ctgatgtcaa gaaattatgg aaaacgcttg atatcagtta tgataaattc attcgcacga
    41761 cagatgatta ccataaagca gctgttcaaa aaatatttga tcgtttatta gaacagggag
    41821 atatttactt aggtgaatat gaaggctggt actctgtttc tgacgaagaa ttctttacag
    41881 aaacacaact tgcagaagtg tacaaagatg acgaaggtaa cgtgatcggt ggtaaagcgc
    41941 caagtggaca cgaagtagaa ttggtaaaag aagaatcata cttcttccgc atgagcaaat
    42001 acgcagaccg tctattggaa tactatgaag aacatcccga attcatccag ccagaatctc
    42061 gtaaaaacga aatgatcaac aactttatca aaccaggatt agaggatctt gcagtttcac
    42121 gaacaacttt tacttgggga gtaccagtca agagtgatcc gaaacatgtg gtgtatgtat
    42181 ggatcgatgc attatccaat tatattactg cactaggata tggctccgaa gatgaaagtc
    42241 tattcgaaaa atactggcct gcagatgttc agatggtcgg taaagaaatc gttcgctttc
    42301 atacgatcta ttggccaatc atgctgatgg cccttgattt gcctctacct aaaaaagtat
    42361 ttgggcatgg ctggctattg atgaaagacg gaaaaatgtc taaatcaaaa ggaaatgtcg
    42421 tttatcctga aatgcttgtg gaacgttatg gtttagatgc actccgttat tatttgcttc
    42481 gtgctgttcc gtttgggtca gatggtgtct ttacgccaga agattttgtt tcccgtgtca
    42541 attatgatct ggcaaatgat ctagggaact tattgaatcg aacgattgct atgatcaaca
    42601 aatattgtga tggactcgtt cctgactatg cctcacttgt cactccattt gatagtgaac
    42661 tgtctacgac ggctgctaac gttgtcggac gttaccatga tgcaatggaa aaaatggaat
    42721 tcaatacagc attggctgaa atctgggtgc tgatttctcg tgcaaacaaa tacattgatg
    42781 aaacagaacc atgggtatta gcaaaagacg aagaaaagaa agctgaattg aatagtgtca
    42841 tgatccattt agctgaatct ttgcgtatcg cagcgatatt acttcagcca atcatgacag
    42901 aaacgccaga gaagatcttc aatcaactag gattggactc tgaaacaatg aatcttgaag
    42961 gattacactt tggcgaattt ccttcaggaa caaaagtagt tgcaaaaggt acaccaatct
    43021 tcccacgttt agatatggaa gaagaagttg cttttattca agaaaaaatg tctgaaggta
    43081 ctcaaacaaa cgaagataca gtcaaatggg atccagaaga aacagaactt gtttcaacga
    43141 aagaaaaaca aatcaaattt gatgtatttg aaaaagtaga actaaaagta gcagaagtca
    43201 tcaactgtca aaaagtagaa ggggcagata agttgctgca attccgacta gatgctggag
    43261 acagccaaga ccgtcaaatc ttgtcaggaa tcgctgaatt ttatcctgat ccaagcgaat
    43321 tgatcgggaa aaaagtcgtc attgtagcaa atctgaaacc acgaaagatg cgtggacaaa
    43381 tcagtcaagg aatgatcctt tctgcagaag caccagatgg ctctttacaa gtaatcgaag
    43441 caccaaaatc catgccaaat ggctcagaaa tcgcatagaa attcaaaggg ggtatgacac
    43501 tagttgtgtc ataccccctt tttccgaaat ttgagaagca attttcgtaa attccttctt
    43561 attacttgaa gccaatcata taatacagaa acagagaact atccaaaata aatcctagaa
    43621 aaagaagtac gagcttcgct gatttttgtt aatttagaat aatactaata ggaatcgtaa
    43681 aaacagaaaa aaagcataat gataaagggt cgggcagatt ttaattgatt catctggtac
    43741 tcttttttat tgtccttaca ttcataaagt ttgaatgcaa tgactttatt acatctatat
    43801 ttatatctaa cagtagcgtt gatgtgttaa ttataagttc tatcacttta tgttcaatta
    43861 gtttgtgctc ttatatgtgt gattgaaaat atagataaaa aaacaatcat cggctttgac
    43921 ttcgatgatt gttttcttta ttttgtaaaa atcctatcac ttgattttat ggtaaccttt
    43981 tatttttgtc ttcaaacggc ttggtaagag agcagtaagc agtgcaaatg ggatcgaaaa
    44041 gacataccag aaaatcgtac gtccgatacc ataatgttga tagagctttg tcaacatcac
    44101 gtgtaacaag atcaacccta aaagcaagga gccagctata aaccaatgat tatcccaatg
    44161 catgacttca ctaagtgcca tcactccaaa aggatagaaa taaaaataga tcccgactaa
    44221 ggtcatccgc cagttctttg taaatgttcc gatattcaat aaaaagaaaa tcgctgaaag
    44281 caaaataccg ataggcggaa aaagcccaac caaaaaggaa tacaacatcc cccacaagat
    44341 catcacagga cctttgatca atgcaacgat tgcgatgaac aaagtcagca atattagttt
    44401 ttgtgataac gttgcaacag tcattaatcc aaataaaatt aatgtgaacc aatgccaatg
    44461 ggactgctgt tgttctttac gggaaaaatc gacccggttg gataaataat ctgctaattt
    44521 cggataagaa cgcttaaaat ccataaactg ttcctccttc gtggaaaagg taggtttagt
    44581 atacgaaaaa taaaaaagaa atacatccgt cttaagaggg agtttttcac tgaaagtgga
    44641 gaaaaaagaa tggtaaatta aaatattctc agttatactg aaaattatac caaatttcaa
    44701 agaagaaaga ggatgggaat gaaaggcaaa ctaaaacgag aaatcaatct gtttggcgca
    44761 ttagctaccg ttatgggaac cgtgatcggt gcaggcgtct tcttcaaaac tgctgctgtt
    44821 actgctagta ctcagtctac aagtttgaca ttgctagctt ggcttttggg tggtttctta
    44881 acgatctgtg ctggattgac agtggctgaa ttagctacag caatcccgga aactggtgga
    44941 gctgtaaaat atattgaagc tgcgtatgga aaattgccca gctttttatt aggatgggcg
    45001 caaagcttga tttactttcc tgctaatatt gctgcattat cgattatctt tgcgacacaa
    45061 ttgacgaact tattacaatt atctaccgat tatcttttgt tgattgcagt gatcaccgct
    45121 gtttctgtga cagggttgaa tttgttaggg acaaaagtcg gtgcttctgt acaatcagtg
    45181 acgttgattg ttaaattaat accaattgct gtgattgtca tatggggatt attgacccca
    45241 ggacaaggaa ctgtccagtt atttccaatc gaagctggaa aagatgttac ttttgtcgaa
    45301 ggattgagca gtgcgttgtt agcaacgttg tttgcttatg acggctggtt aggtgtcggt
    45361 gcaatggcag gggaaatgaa acggccggaa aaagatttgc ctaaagcaat tattcttggt
    45421 ttgagttttg taacagtcgt ttatctattg atcaattttg tttttttgaa aactttgccg
    45481 attgatcatc ttgccggtaa tttgaatgca gcttctgaag catcagacgt catttttgga
    45541 ggaatcggtg gaaagctggt cactattggg atcttgatct cggtatacgg tgcattgaac
    45601 ggttatacac taactgggat ccgcgtgcct tatgcgatgg ctttagaaga cgagctacct
    45661 ttcagtaaac agctgacaaa gctttcaaag aagtttacgg ttccttatgt tcctgcggtt
    45721 ttccagttag cagtagcttg tattatgatg agccttggtt ctttcgactt tttaacagac
    45781 atgttgattt ttgtgatgtg gctattcagt ttactgattt ttatcggtgt ctttatttta
    45841 agaaaaaaag cgccggaatt gccacgtcca tataaagtac cactttatcc aatcgttccg
    45901 attattgcga ttctcggtgc tattttcatt ttaggtatga cgatgatgac gcaaacgaaa
    45961 ttagcattga tcggtatagg tgttaccttg ataggtatcc cagtctatta tcaaaaaaag
    46021 aaaaaacgct cagaagagta aaatatttca acaacagaca gaaaaagtac gaactaggtc
    46081 ctctagatct tcgtgctttt tctatttcaa taaaacaagt tcttctattt tgatttttgc
    46141 tacttctgca agtagtgctt atgtgctaaa gtaagaatga aaaggagaga taaacatgat
    46201 atttgattct catacccatt taaatgctga acagttcaat gaagatattc cagaaacgat
    46261 tcagcgagca caagaaatgg gggtaacgaa aatggcggtc gtgggcttcg atacgccaac
    46321 gattgaaaag tctttgcaat taagccatga ctatccaaat atatacagta ttatcggctg
    46381 gcatccgaca gaggctggca gttatacgaa agaaatcgaa aataaattac aagaacaatt
    46441 gactttacca aaggttgtag cattagggga aattggcttg gattatcatt ggatggaaga
    46501 cccgaaagaa gtccaagata aagtatttcg cagacagatt gctatcgcaa aagaaatgaa
    46561 cctaccaatc agtattcata ctagagaagc acttgaagac acgtatcaaa tcctaaaaga
    46621 agaagatgtt cgagatatcg gtggaatcat gcatagtttc agtggtgatt atgaatgggc
    46681 aaaacgattt cttgacttag ggatgcatat ttcatttagc ggtgtcgtca ctttcaaaaa
    46741 agcattagac gtccaagagg ctgcagcaaa tgtaccaatc gaacgattac ttgtggaaac
    46801 agatgcccct tatctggcac cagttccttt tagaggaaag cgaaatgaac caggctatac
    46861 tcgttataca gtagaaaaga ttgctgaact tcggaatctt ccgacagaag aagtggctgc
    46921 ccaaacatgg acaaatgcgc accgattatt tggtctaagc gaacatggat aagatgaaga
    46981 tccaagagat tatagtcgtt gaaggaaaag acgatacaag aaggctgcgg gaagtagttg
    47041 atgcagatac gatagaaaca atagggtctg caatcaatga agagatcctg atgcaaattg
    47101 aacatgccca agagactcgt ggagtgatcg tttttaccga tcctgatttt tcaggagaaa
    47161 aaataagaaa aatcattatg gaagctgttc ctcaggcaaa acatgctttt ttgccgcgca
    47221 cacaagctaa accaaagaaa aagggaagcc ttggtgtcga gcatgcaagt gatgctgcta
    47281 ttttagaagc attgaaaaag gtcgtgacgc cagacatttc ccaaacggct gtttctgaaa
    47341 tcactagaca agacctttta gactatggtt taatagctgg ggcacaagca aaagaaaaac
    47401 gagaaaaact aggtgacgag ttgcgcatcg gttacacgaa cggcaaacaa ttggaaaaac
    47461 gtttgaagat gtttcgtatt acgccgaaag aactcgccca agcaatgaaa atagtggagg
    47521 aacaacatga gtgaatatcg tgaaattgcg acaccctcta gaacaaaaga gattttattg
    47581 aaacatggtt tttcatttaa aaaaagttta ggacaaaatt ttctgactga accaaatatt
    47641 ttaaggaaaa tcgtagaaac tgcgcaaata gatgaacata cgaacgtgat cgaagttgga
    47701 ccaggaatcg gtgcattgac ggaacaatta gccaagcatg caaaacaagt cgtagcattt
    47761 gagatcgatg atcgtttgat ccctgtattg gctgatacga tgcaacccta tgacaatgtg
    47821 actattgtac atcaagatat tttaaagacc gatttgtcaa cagctgttag agaaacattt
    47881 catgaggagc ttccgttaaa agtcgtagcg aatttacctt actatattac gacaccgatc
    47941 atgatgcatt ttcttgaatc agatttggtt gtggatgaac tagtcgtcat gatgcaaaaa
    48001 gaagtagctg atcgtatctc tgctgaacca ggaacgaaag cttatggttc attatcgatt
    48061 gctgttcaat attatatgga agccagttta gcattcatcg taccaaaaac agtatttgtc
    48121 cctcagccaa atgtagattc agcgattttg aaactgacaa gaagagatat accggcagtc
    48181 gaagtgacag acgaaaaagc atttttccga ttgacaaaag cggcatttca gcaaagaaga
    48241 aaaacgcttt ggaataactt gcagcattcg tatggcaaag atgaccagac aaaagcatgg
    48301 ttagcaaaaa gcttggaaac agctggaatc gatccaaaac gtcgtgggga gactttgtca
    48361 ttacaagaat tcgccgcatt aagcaatgcg atgtcagaaa atatgcagta aaaaaagagg
    48421 ttgtgacaga agttgtgaaa aagctgtcct gcatcaagta ataagaacag ccaaacaaaa
    48481 atagttcctc atgtttttcg tttgtttggg cttattaccg cagatgcaag cttttgaaca
    48541 ccgtttaaga aagaggttgt gggcctgccg tttaactcta agtcacaagg aacaatttca
    48601 aaaaacagct tctcatgttt ttgagttagt tggtcttatt acttgatgca agcttttgac
    48661 cactattatg ccgaacaagg agatgtgaca caaattttgt cacatctcct atttttgttt
    48721 cttgatcaaa aaattcttat acttgatact cacactcatt ttgtatggat ttagaaaaga
    48781 atatgtgtct tgacagttat tagtaagtga gttatactaa gtcgacattt atgtgtcaag
    48841 acatattagg agagagaaaa aatgagaaaa aattcagttc gaaaactaac gatttctgct
    48901 ttattgattg ggatgggggt cattatccca atggtcatgc ctaaaatcat gattccacca
    48961 gcttccttta ctttggcgtc tcatgtgcca ttatttattg cgatgttttt tacaccagga
    49021 gttgcagtgg ctgttgcgct aggtacgaca tttggtttct ttttaacaac gccggttatc
    49081 atcgcattgc gagcattgtc acatcttgtg tttgcgttga ttggggcttg gtacttgcaa
    49141 aagcatccga gtatcgtttt aaaaaatgga cagtttactt ttgctaattg gcgtttccaa
    49201 gggttcaatt ttgtgatcgg tgtgattcat tctttagcag aaatgctagt agtcagcatc
    49261 ttttacttta ttggtaatat gcctgaaaca tattattctc aaggatattt ttatacagta
    49321 ttcatcttga tggggattgg tgggcttatc cacagtttag ttgattataa tattgcttat
    49381 tttatagcag gaacactcag caaatatttt gatatccccg tatttacggc agcaaaaaaa
    49441 gaaaatcgga aagagtcgat tcaagggtac gcgaagaaaa cgacatatta gacatgatct
    49501 ctcaaaaaaa aaactctcat ctagtaatgg ataataaatc ctctaagatg agagtttttt
    49561 gtcctaaaaa gagctgcacc aacatcttct ggcacagctc taacaggggg caatttatgg
    49621 aagtttgatg acttgttctg tttctttatc aaagaagtgg cctttgctga tgttgaaggc
    49681 aaggtcgact atttcgcctg gtttatggaa atctcttgca tctacttttg agatgaactc
    49741 agtagaacca gtttttgtgt aaagcatcgt ttcagctcca agtaattcgg aaacgacaac
    49801 ttctgatttc actacggctt caggtgaagc ttcaagggct acttgttcac tgtggatgtc
    49861 ttctggacga ataccgaaga taacttcttt tccttcataa cctttttcaa ctaatacttt
    49921 gttttttcct tcaggaatac gaagcttaag cccatgtcca tctgtgataa caccattttt
    49981 caatgtcaca ttaaagaagt tcatggcagg agatccaata aagccggcaa cgaacatatt
    50041 gacgggtgta tcataaactt ctttcggtgt accgatttgt tggataaatc cgtctttcat
    50101 gataacgatt cggtcagcca tagtcattgc ttctgtctga tcgtgagtaa catagatggt
    50161 cgttgtttca agacgctggt gaagtttggc aatctcagca cgcatggcta cacgtaattt
    50221 agcatctaaa tttgataatg gctcatccat taagaagact tttgcatccc gaacgattgc
    50281 ccgtcccaat gccacacgtt ggcgttgtcc accagataaa gcagctggtt ttcgtttcaa
    50341 gtattctgtc agacctaaga tctctgctgc attgtccaca cgttttttga tgtctgcttt
    50401 atcatattta cgtaatttca agccaaaagc catattatca aaaacagtca tatgaggata
    50461 caatgcgtag ttttggaaaa ccatggcaat atcacggtct ttaggtgcca cgtcattcat
    50521 gacttttccg ccgatattta gttctccttc agagatatct tccagtcccg cgatcattcg
    50581 caaagtagtt gactttccac aaccggaagg accaacaaaa acgataaatt cacggtcttt
    50641 gattgataga ttaaaatcag ttacagaata attttctgca ttgtcatatt ttttatatac
    50701 gtttttcaga gccatttcta ccataatacg ttccacactt tcttttttag ttttattaac
    50761 tatttaaagt ataaatgaaa gcgttaacta acttcaatgt catgttgaac aagaattttt
    50821 tctttttttt gtcaatgtgc tagttttaag ctttaataaa tatccataag aaataaaaac
    50881 tgatacactg gagtaaataa gtatgttaac aatatcaaaa ggagtgtctc ttatgaaaat
    50941 cgctttgatc gctcatgacc gaaaaaaacc tatgatggtg aaattagcaa cagcgtataa
    51001 aacaatattg gaaaaacatg aactttttgc taccgggacg actgggcaga ggatcacgga
    51061 agcaaccggc ttgccgatcc atcggtttaa atccggaccg ttaggcgggg atcagcaaat
    51121 tggagccatg atttcggagg atcagttaga tttggtgatt tttcttcgag acccgctggc
    51181 tgcacagccc catgaaccag atgtaacagc acttatccgt ttatctgatg tctatgagat
    51241 tccgttagct acgaatatcg gaacagctga ggtgctacta agaggactgg aagccggctt
    51301 cctagatttt cgaagaatcg tccatgaaat agacaagcat ccactttcat tttgatggat
    51361 aagcgtatgg aaaaataacg tttaatgttc gcctatatgt agctataaaa gctaaacaaa
    51421 ctgataatat gcgatataat acgaacgtat tggataatat aaacaataat attagttttt
    51481 cgtatttgca gtaaatgtga aaatatgcta tagtttctgt gggaaaagat cccaaaaata
    51541 atacagagta gaaaataaag cgttaagtgc taagaggatg ggatgttgcc tcttggacga
    51601 aggacgtaat gttcgcggtt ttattttcgc attcgctgca tgatacgatg tagcagctct
    51661 taaaggagat gctaaaaatg aagaaacacc ggttagacgc acgtatgatt gctattatgg
    51721 gcttattgat tgcattgatg gtcactttgt cccgactggt agcaatcgag accccattta
    51781 ttaaaatcag tgtcacattt attccacaag tgatcatggg cattcttttt ggtccttttt
    51841 ggtcagggat aggcgcagtt ttagctgatt tagtaggaat ggccctcttc tcgaaatctg
    51901 cattctttat tggatttaca ttgaatgcat ttattgaagg agcaatctac ggattctttt
    51961 tctatcgaaa agagatcact tggaaaaatg ccattctggc tacgcttagt gtcacgctga
    52021 tcatcaactt atttttgaca ccattatggc ttgcgttgat gtaccatgtg ccattgttca
    52081 gctgggtcgt ttgggcgccc cgcctgttaa aaacagtaat atggttaccg attcaatcaa
    52141 ttgccattta ttacgtagga cgtagtattc cttacaaaaa aattttaaga agtttagcga
    52201 tccacgctaa ataaaaaaca agcagtcttc ccatcccaga agactgcttg tttttattgt
    52261 gctgtgaatt gtgcttgata gagccgtcgg taataaccat ctttttgaag cagctcatca
    52321 tgggtgccca tttcgacaat agctccctga tccatcacta atatctggtc cgcatttttg
    52381 attgtggaca ggcgatgggc aatcacaaaa ctggtttttc cttccatcat tgctaagaag
    52441 gcttgttgga tttttttctc tgtcaatgta tcgactgagc tggtagcttc atctaagatc
    52501 aacatagggg gattactgat catcgttcga gcaatcgtca acagttggcg ttgtccatct
    52561 gatatcttta acccttgacc gccaatctta gtatctaatt tttccggcaa acgttctaca
    52621 aattcataca tataagaggc ttttagggca tcattgattt ctgcgtcact tgcttccgga
    52681 ttcccaaaac gaagattttc tcgcaatgta ctgtcaaata gccaagtatc ttgtaacacc
    52741 attccaaaac ttttacgtaa tgtatcacgt tggatagagc ggatgtcatg gtcatcgact
    52801 gtaattgttc cttttgttgt gtcataaaaa cgcatcagca aattaacaag tgtggatttt
    52861 ccggcccctg tttttcctac tatagcaatg gtttgacctg gataagcagt aaaattgaaa
    52921 tcttcgatca aacgctgctt ggggtcataa gaaaaagaaa catgatcaaa agagactttt
    52981 cctttgatat ttttgggttc caaggcatag gcatctggca aatcaggctt ttcttctggc
    53041 tgatcgatca aatcaaatgc tcgttctaga ccagaaaaag cggtttgcag ttgtgtcgtg
    53101 attccagaaa gttcgataaa tggtttagaa aactgacttg agtagatcgt aaagctggaa
    53161 atcacaccaa cagtgattga cgaaccactc ttcaatgcca ataggccgcc aactaaacca
    53221 atcgataaat aagcaaggtg atctacaaaa cgagaagacg ggtttgtcaa ggaagaagaa
    53281 aattgtgccc gttgtccttt ttcatataga tcagcattta gcagttcaaa ttgctgttga
    53341 ctagcttctt cttgctgaaa agctttcacg attttctggt taccgattcg ttcggtcaca
    53401 aagcccgaga tatccccaat aatcctttgc tgtctatcga aatttgtttg tgaagcacga
    53461 gcaacgatcc aactcacaag gaaaataatt ggtgtagaac aaagaacgac caatgtcaga
    53521 agtggactta gacgcatcat aaaaataaac gaaagaatga tgattgccac tccagaaaat
    53581 aattgattga aggccgcaga aattgcaatg gaaatattgt ccatatcatt tgtaaatcga
    53641 ctgacgatat ttccgtggga gttttgatca taataacgaa gtggcaatcg attcagatga
    53701 gcaaatgcat cttttcttaa ttttgcaacg gataagtaag ctaaccgatt gcttaacact
    53761 tggatgagcc attgactgac tacgttgatt aaaacgatac caccgaatag aataagtaaa
    53821 tggaacagtc gattgaagcg gacctgtcct tctccaatca tttgatcgat actttgacca
    53881 atttgtaacg tcatcacaac tgttgcaatc ccattgatga ttcctagtat cacagctagc
    53941 caaatgtctt ttgcataggc agtaaggtaa ggaatgaatc ggcggagcgt ctgcaaggat
    54001 aattttttta ctttcataac tattcttcct cctgtgatgc gacgatttcc tgatattctg
    54061 ctgattgagc aagtaattct tcatgggtac cctgagcagc aatcttacct tgatccatca
    54121 ctaagatatg atgtgcttct tgaatagagc ggacacgttg ggagataata atcactgtac
    54181 tgccaagata agtctgtagc gccttacgca aatccaagtc tgtttgataa tccaacgcac
    54241 ttaaagagtc atctaaaatc agtaatgctg gcttggcaat caaagctctt gcaatcgtca
    54301 gtcgctgttt ttgtccgcca gagaaatttt tcccattttc catgactttt gtatctaaac
    54361 catttggaag ctgacggaca aattcttctg cctgagcgat tttcagagct tcccaacatt
    54421 ctttttctgt ggcgtctttc ttaccccatt gaaggttttc acgaatagtc ccggtaaata
    54481 gtacagaagt ttggggaaca agagcaattt gctgacggag atgatccagc tgccaagaac
    54541 gaacatccat tccgtccatt ataactgtac cggaactgac atcatagaaa cgcggaatca
    54601 attgtgtcaa agtcgttttc ccgcttccgg ttggaccaat gattccaagg actgtatttc
    54661 gcttcagctg aaatgtaata ttttggagag aaagaccaga atcaggagta taacggaagt
    54721 caacatggtc aaaagcgata attgcttcag aagaaaaatc gggagtagta ctgacctcag
    54781 cttcaagaat cgaattttct gtgtctagca cctctttcac ccgatttcct gaagcttcgg
    54841 cacgtgtgaa gatcacgacg aggtttgaaa caacgatcag tgccaaaagc atttgattca
    54901 tataattgat caaagcaaga acttgtcctt gttgcaagct accaatattt actttgatcc
    54961 cgccaactgt cagcaaacag atgatcccga cattcatgat caaggttgta gcaggtgata
    55021 atagggcaga gatattggaa acacgtaaat aattgttcgc tagatcattt gtgcttttat
    55081 cgaacttctc tgtttctttt tttgtctgcg caaatgcgcg gatgacacga acaccgctaa
    55141 gattctgact aacgtgttca ttgagctgat ctagtttttc ttgcactttt tggtagagag
    55201 gaacggtttt tttgatgata aaaaataaaa tgattgagaa aataggcaat aatgctaaga
    55261 aaaacagacc tacttcccag tcgatcacaa aagccatgac cactgacccg atacttaaaa
    55321 acggtgctct gatcaataaa cgaatgacca ttgctaaagc tagctgaagc tgattgatgt
    55381 cgtttgtcat tcgggtgatc aaggtatctg ttccaaaatg attcaactcg ttgtgagaga
    55441 aagtattgat ttttttgatt agctgattac gtaactctgt accaaatcct tgtgaagcta
    55501 ctgaagcata gtattggcaa atgatagcac aaatcagacc aatcacagac atagcgacca
    55561 tccataagcc catttcaatg atttttcctc ggtcattcat ttttagtcca ttatcgatca
    55621 aggaagccat cattaaaggc aggacaagtt cgaagacagc ttcaagaaat ttgaagaacg
    55681 ggcccaaaat gatttgctta cgatagtctt ttgcataacg taataactga atcatatgat
    55741 tcctcctatt atttatttgt ccacaattga aaaaacaagt actaccacat tgtagcttag
    55801 gaaatttaga atgaaaagag aacaagcctt ttcataaatg aaagttttat tatgaagaag
    55861 ctttagaaat tgaatagact atttttttta aaaaaaagaa aatgagaaaa catgccagtc
    55921 tcttcattca taggaacgtc tattttactt aatttttcta taaatgaatt ctgcataaaa
    55981 aatatatcaa gtaaatgttt atagatgaaa ctctatttac ttctttttta atttgttctt
    56041 gcaatctttt ttgctacgta atttttgtaa aaaagtgggt tgagagaaat ctaattgatt
    56101 ttcaaagaag gagtatgaaa atgagaaaaa tatttattcg tttattgtgg gtactatctt
    56161 agaggaataa ataatagtgg agaaaactat ggtttggcgc agattctatc aggtttgatg
    56221 gaacgaagac aacctcccga catcaagtca aaagctactt gagattttga tctgaaaata
    56281 aaaaaagaaa acaaggtagg aacatcaatg tttctacctt gttttcgtaa tcaatgggaa
    56341 aaaactaaga gtggtgtacg taatcaataa aaaggatggt gacaacagta cctctttact
    56401 ctctgaaagc atcataactc gtttttcctc attatgccaa taaattgttg ttataccaca
    56461 tataaggatt tgtaatagct aaaaacagac aggaaagttg aaatctgtga atcttatttt
    56521 gtatggaagg atttatagaa cgcaaaaatc aagataaaga tgaataaaaa tcctgtttcg
    56581 gctatatatt gcgtatctac gccaataaaa cgagtttgtt ctgtcatagc catataaagc
    56641 aaaggcaaaa atacaactac agcgagataa gatccgatga tttctcgaaa agttttccag
    56701 gaagtatgtt tcctgttttt atatttatcc gatttcattg aatagtcata gcctccttat
    56761 tctttcatat gttgaaattc cagtataaaa actggaagga actgtacgtt ttttagaata
    56821 aaaattataa gggataagta ggctgctgtc tataataaga tatatttttc aattctttat
    56881 taaagatttt attgacaaaa tgaatccgtt ttctatgatg gaggaggggt gaataagttg
    56941 ttgaagaagg aaattttatg ttacttagag aaccagacag cctttttcga tttagaacat
    57001 atgaacgagg tctttacagc acaaaggtta gctgatcatt ttggggtaaa aagaaacaca
    57061 gtcagtcatt atttgaacca gttaaatgat gagcaactac tagtcaaaat caattctcga
    57121 ccagtgattt atttccacaa agaagctttt gaaaaacaat tttttaagtt acgcacgaat
    57181 ttttattttt ctatcgatga tctcaaagag gaacagcctt ttttcgcgca accaaaagac
    57241 ttattctctt ttatgatcgg atacgacgcc agtttgaaag aaagtatcga acaaatcaaa
    57301 acagctcttt actatccaga tggcggatta ccacttttga ttacaggcga aagtggcaca
    57361 ggtaaaagtt atttagttaa tttggtctat cagtattgtc tgcttcatga tctgctagaa
    57421 gattctgcac cattcatcac ttttaattgt gcacaatatg cagataatcc tgaacttttg
    57481 actagcaatt tgtttggaca tgttaaggga gcgtacactg gtgcagaaga aaataaaaaa
    57541 ggggcttttg aagcagcaga tggtgggatc ttgtttttag acgaggtaca tcgcttaaca
    57601 ccagaaggtc aggaaaaact gttcacctat cttgatcaag gtgtgattta tcgtatggga
    57661 gaacctaatt tgtcacgccg gatcaaaaca cgtctctttt ttgctacgac tgaagagatt
    57721 actagtcatt tcttaacaac tttcattcga agaataccta tccgaatcga actacctgca
    57781 cttaatcagc gtagtcgtaa tgaacggcta gaactgattt actctttttt tctcgaagaa
    57841 caaagaaaaa tggggagccc tttgtcagtc agtggaccag ctttgtcact tttaacaagt
    57901 cagaaattat ccggaaacat aggagagctg aaaaatatcg tcaaagtttc agcagcaaaa
    57961 gcatatgctg aacagcgtga acagcctgaa atccatgtca cgatccatca tttgcaaaaa
    58021 gaactacttg cgcagcctat tactaaaaat acagcacagc aaggaatcta tattacgcaa
    58081 gaccagacct tagagcaatt aatggagaag caacagcccg aacagcagcg aatcgttaaa
    58141 agttttgagc aaatcctaat tgatttcaag aaaaataact gtctgctata ttcttgcgaa
    58201 ggaaaattaa agcaagaagt gattcaatta tttgattttt tgctgtttga gaccagtaga
    58261 caagaaaaac acgagctgct ggtttattgg acacaatcta tccgagagac ctttcgacaa
    58321 atggaaactg cctatcaaat caaattcgat ggaaacagtg tctatgcctt gagttactat
    58381 ctctatcagc gaagcactat caaatggtta ccggaagaac atgatattat ccaactaatc
    58441 aaagaattag aacaacaagt ttctcagtct tatccatcta gttatcacta tgtccaacga
    58501 attctggaat taagtaagat caaattagat attgaagaca caagtatgga tcggatttta
    58561 ctgacgatct atctaaaaaa agcgaaatgg tcaaaagaaa aacgactgcc aaaagcgatg
    58621 attgctgctc acggttatgc aactgctagc agtatggcaa atgtagtaaa tcgtttatta
    58681 caagaggatc tatttgaatc atttgatatg ccactagatg tcacaccaca gcagattgct
    58741 tcagaaatcc ttgattattg cgaaaacagc gatgtttcaa atggattgat catattagta
    58801 gacatgggat ctctgaaaga aatccatcag ttttttaaaa aacagttatc cgtaccgctt
    58861 ttgattttga ataatgtgac gacaccttta gcaatcacag taggggaatg cctgcaaaaa
    58921 aatgtatcat tagaagagat agcagaagag actgttcgac agatccagcc agaatggcga
    58981 ctgctctatc cagaggaaaa caaacccaaa gcactcatta ctacttgctt cactggaatc
    59041 ggtacggcgg tccacttaag tgaactgcta gaaaaaagct tacctacggc ttgtcagttg
    59101 aaaatcatcc catatgaata tcagcaatta aaagataaga aaaacagtga cccattattt
    59161 tccatatacg aagtcgtagg aatgattggc accacagatc ctgatatcac caatatcgac
    59221 tatctttcat tagaagacct catctcgggg gaaaagatgt ctgtactagc tgaatggttg
    59281 gacactacta tgaatgcttc agagaaggaa atattcaatc agcgcatcat tcgtaatttt
    59341 tcattggaaa aagtactgga ttccgtgact attctagata cagagaaggt gatgggagaa
    59401 atcgatcatt ttatgagaga attagaggtg cagttgaatc gaagcatcag caatcccaaa
    59461 aaattagcgt tgtatgtcca tgtgagctgt ctcattgaac gattgatccg acaaatgcca
    59521 atcgaaacct atcaaggatt agagaaatgg aagcagtgtc aaaaagaagg gttatctgct
    59581 attaaatctg cgtttagtgt cattgaagag cattatagtg tcatgatccc caattctgag
    59641 attgcctata tctatgatat tttgagtgaa gatacagagt ttctctcgat agaagaagaa
    59701 ttttgaacat aagcaagttg ttgccactaa ttttggcatg caacttgctt ttttagtatg
    59761 tgtaagtgaa aagaggagat gaaaaagtgg atagagaaat tatcttagct tcccatggaa
    59821 aatttgcttc agggatatta gattcattag agctgatcta tgggaaaaat cattctatta
    59881 ctgtattcga ttgctatact gatgagaatt ttgatttagc ggaaacagta aggcagcttt
    59941 ttatgaggta caaagataaa gaaatcattg ttctgacgga tctttttggc ggaagtgtca
    60001 acaacgaatt cttacaatat atcaatcggg atcatgtcta tctcgttgcc ggattgaatt
    60061 tgccactatt gattgagcta gtatctcggt tggacgctga agtagagaca actgttttga
    60121 tccagcaggt gctaactgat tcaaaaaaaa tgatccagtt ttgtaacgag cggctcaatc
    60181 agaaaataga agaagacgaa ttttaggagg aagaaaaatg attgtattga caagagtcga
    60241 ccatcggtta ttacacggac aagtagcttt ttcatggaca caaacaatag gcgcagactg
    60301 tattttgatt gctaatgatg atgtacctac gaatgagata cgaaagacaa cgatcaaatt
    60361 agccaagcca caaggagtca aactagtgat caaatcaatt gatgactcga ttgccgcgtt
    60421 gaaaagcggg gtgacagata aatataagtt attcatcgta gtggaatcga tcgaggatgc
    60481 atataagctg gcagaagcgt atccagaaat caaaaccatc aacttaggag ggatcaaggc
    60541 aaaacctggt actcgcagca tcggaaaagc ggtaaatatt ttaccagaag aggaggaacg
    60601 cttgaaacga ttaattgaca aacaaataga agtagaaatc cgtcaagtac cagcagataa
    60661 aaaagtggat gtaagagaag ttttgtaaga aaggaagaac ctcaatgatt gtacaagcag
    60721 tcttattagg aattgttgca tttgtcgcac aatcagaata tgcactaggg acatcgttgc
    60781 tttctcgtcc gattgtgacg gggctgttta caggaatcgt gttaggtgat gtaaaaactg
    60841 ggatcattat gggcgcaact ttagagttag catttatcgg atcgttctca gtaggtgctt
    60901 cgattccacc tgatgttgtg accggtggga ttttagggac ggcttttgct attacagctg
    60961 gagccggtac agaaaccgcg cttttactag gtttgccgat tgctacgttg acattgatat
    61021 tgaaaaatat ttacttaggg cttttgattc caattatgaa ccataaagca gacaattatg
    61081 cagaagaagg aaattataaa ggagtcgagc atatgcactt gcttgccggt atcggtcttt
    61141 ccttgatgct tggtgttgtg gtaatggttt cttatatggt gggaagcaat acgatcggaa
    61201 atctattaaa tatgattcct gacttcgttc aaaaggggtt gtcagtagct acagggttga
    61261 ttccagctct tggttttgcg atgcttgctc gtttgctgat caacaaacaa gttgcaccat
    61321 attttttctt aggttttgct atagcttctt acttagagat tcctgtgacc ggagtagcta
    61381 tttttggtgc gattttagca gttgtggtag tcaatattat gaatgtccgt caactaccac
    61441 ttcaaacaac tgcaggggag gtagaagaag atgaagaatt ctgagatcaa aaacagcaaa
    61501 ataacgaaaa aagagctaaa tcacgtattt tggcgttctt ttcaaatgga gttttcttgg
    61561 aattatgaac gtcagatgaa tatggcttat gtttatgcaa tgattccgat tttgaaaaag
    61621 ttatatcagt cgaaagaaga aatggcagca gctttgaaac ggcatctaga gttttttaac
    61681 acgaccccac atatcgttac actgatttta ggaatcacgg ctgcaatgga ggaagaaaat
    61741 aaggatgatc ctgaatttga tgtgactgcg atcgatagta tcaaaacatc tttgatggga
    61801 cctcttgcag ggttaggaga ttctttcttt tggggaactt tgcgattgat tgccacaggt
    61861 gtgggtacct ctttagccat gcaaggaaat attttaggcc ctatcttgtt cattttgatt
    61921 ttcaatattc cgcacattct gtttcgctat ctagcaacag gttggggata tcgcttagga
    61981 acgggttttt tgaaaaagat ccaggcaaac ggtatgatgg aaagtttgac attaggcgcg
    62041 tctattattg gactgatggt cgttggagca atgactgcca cgatgatcac catcaatatt
    62101 cctttaaaaa tcggttcagg agaaaatgct gtgactgttc aaagtatttt tgatgatatc
    62161 gttccaaata tcttatgtct tggagcattt ggcatagtgt tttatctatt gaagaaagaa
    62221 gtgaaaccat taacgatctt gatcggacta gctttctttg gaatttttgg ttcgtggata
    62281 gggatttttt aaaaaaggag cagagaaaat gtttacgatg caagattata tctatgaaga
    62341 aaaggaagta ctaagtacga tcttgaaaaa gaatgatttt tcgacaagag aacatatgaa
    62401 aaaaacagtg aatttactga tcttagcaac gggttcatct tataacgctt gtttagcagc
    62461 gaagccagca ttggaatctt atggtgatct tactgtcgat attcaagaac ctttttattt
    62521 tttcaattat ggaaaacttt ctccttcaat cgatactgtg attgctgtgt cacaaagcgg
    62581 gaaaagtgct tctactgttg aagcagtaaa aatgatacaa aaacaagggt tacctgttgt
    62641 tgctatcaca aatgacgtgc aaagtccact tgctttagaa gctgcacaaa ttattgattt
    62701 aggtgccggg gtagaatcag taggcttcgt tacaaaaggc tattctgcga ctgttttaca
    62761 gttactactc ttagggatag gaattggaat aagtaaaaat aaaatcagca aaaaaataga
    62821 acaagactac atgcaacagt tgcgcaaaat aatcaaccat ttaccagcga ttattcaaaa
    62881 aacggaagaa ttttttgatg gatatcaaag tttatttcgt ttagcacagc gtttcgtcac
    62941 cattggatat ggtccaaact ggggaacagc taaagaagca gagacgaaat tgactgaaac
    63001 aatccgcgtt ccgtcacaag gatttgagtt agaagcttat atgcacggcc catacctgga
    63061 ggcagatgct tcgcatttgc tattctttat tgaaggggaa agtgtaaata aggaacgttc
    63121 gcaaaagttg caaagatata tgagtcggta cgttggagag actctcacca ttaccacaaa
    63181 aaaagcaaga aacgagaaaa cacttggatt agcaatagaa tgtgatgaat atctgtctgt
    63241 attagcgctt gtcgttccgt ttcaactatt cgcttataaa accgcagtag ctaaaggtat
    63301 tgacttgaac aaaaagattt ttgaagactt tgatacagtc ttgaaaagta aattataaga
    63361 ggtggaaatc atgctgaaat tcaatgaaga agaacaaatc aaagcaataa aaggcgcact
    63421 agctttacgt ccgcaagtag aagaaatcat cgataaactt tatgcggaaa aatttgacgc
    63481 tgtctattat ctaggaatcg gtggaacgta tgcttcctcg atgcaagctg tcacttatat
    63541 gaatgggaaa agcaacttgc ctgtctttgt acagcatgct gcagaatatt acactactgg
    63601 aaacaaaaga ttaacaaaag attctatcgt tattttgtcc tctgttaccg gtacaactca
    63661 agaagtagtg aaagcagtag aacaaatcaa gaaagtagga gcgacactga ttggatttat
    63721 cgataaagcg aacagtaagt tgtctcagct atgcgatttt gtggtcactt atccagctcc
    63781 tggaacagaa caaatcaaat tttttatggc agcagatcga ttgatgtatt tgaatggaga
    63841 attcgaagct tattcagaat actatgaaca gctcgaacgt tatttaccaa cagggttagt
    63901 ggaagcagag aaaaaagcag atgcatttgg cttatcattt gcagaaaaac atcgacgtga
    63961 tagtatgcat tattttattg gagcagggaa tcaatgggga gctgtttatt catatgccat
    64021 gtgttactgg gaagaacaaa gctggcttcc atcgaaatct atccatgctg ccgagtttct
    64081 tcacgggacg ttagagatcg tagaagaaac aaccccagtc acattatttt taggcgaaga
    64141 tgaacagaga gtgttatctg aacgtgtggc taaacttttg ccaaaaattt gcagcaatta
    64201 tacattgata gacacaaaag actatccagt agaaggtatc agtgaaaaat atcgcggacg
    64261 tgttttgtct ttcttattga tgcatgtagt gacacaacgc atcgatgctc atgtggagca
    64321 gttgaactgc catccattag agatacgccg ctactatcgt cagtttgatt attaggatag
    64381 actggataaa aagaatataa aaaataaaga gagcagcgat aactgctccc tttatttttt
    64441 taaaatattg gcatcaatta cgttataaaa cacatttttt gcattatcta cagttcaact
    64501 tataatctgt ttaatgggac atgtgggtgc caaccatttt ttgttatgca atagtactat
    64561 ttagttgttg catggatccg tagtaaaagt ccaagtacaa cgagttgcgc cagtttacat
    64621 agcgttttgt atccagaatg ttgactaaaa caaaagttcc tatgtcaacc gtcaacagag
    64681 acaatctgtc cgttgcagga cctgacagat ttagaaatgt tcaatctgtc tcttatgtat
    64741 tttaaatcaa tactcactag gagaagtttc ctaacctcct aatagtaatg ctggtagtaa
    64801 cattgtcaaa actgcttcct cttaggaaca agcaaagcat aacgagtgta aaaataaaat
    64861 gtagactatt gtaacatatc attgattatt tcaagtaaaa acgataaaag aagtaaacaa
    64921 acacttaaaa acaatggaaa ttagtcccaa ctttaagaaa tgtatactat aatggaaatt
    64981 atcaattatt tatttggagg aatatccatg aaacaaaaaa tcgcagttct tggtcctgga
    65041 tcttggggca ctgctttagc acaaacattg gcagaaaacg ggcatgatgt ccgtatttgg
    65101 ggaaatgtac ctgaacagat tgatgaaatc aataagtatc atacaaatca gcatttttta
    65161 cctgatttga cgatcccaga atcgattatc ggatataaag aattggcaga agcagtggat
    65221 aacgcagatg ctattttatt tgttgttcca acaaaagcga ttcgttcagt cgcacaggaa
    65281 cttattggta aaatgaatac taagccaatc attatacatg caagtaaagg actagaacaa
    65341 gatacgcata aacgaatctc agaagttttg gctgaagaaa ttccagaaga aaaaagacag
    65401 gcaattgttg tattatctgg tcctagccat gctgaggaag tggcagtaca tgatatcaca
    65461 acaattacag ctgcaagtat tgatcaaaaa gcagcagcct atgtacaaaa actgttcatg
    65521 aatgattatt tcaggattta tacaaataat gatgtgattg gcgtagaaac tggtgcagca
    65581 ctgaaaaata tcattgcaat tggtgccggc gctatccatg gattaggatt cggagatgat
    65641 gcaaaagcag caatcatgac tcgaggattg gcagaaatca gccgtcttgg tgtcgcgatg
    65701 ggtgccaatc ctctgacatt tatcggtttg agtggtgtgg gggacttgat cgttacttgt
    65761 acaagtgttc attctcgcaa ttggcgtgcc ggtaacttgt taggacaggg acataagctg
    65821 gaagaagttc tagaaaacat gggaatggtc gttgagggtg tggcaacgac aaaagcagca
    65881 gtagagctag ctcaacagct aggtgttgag atgccaatta ctcaaacaat ctataatgtt
    65941 ttgtataatg gagaagatat caaaaaagca gcaaaagaaa tcatgttacg tgacggaaaa
    66001 atggagaatg aattttctct tcgttaaata gatgatcaat agttaatcgt cgtttaggag
    66061 gaacagcaag tgaaggtcaa aaaagcagtc attcctgccg ctgggctagg aacacgtttt
    66121 ttgccggcaa caaaagccat ggcaaaagaa atgcttccaa tcgtggataa accaacgatc
    66181 cagtttattg tggaagaagc attggattcg ggaatcgaag acatcttgat cgtaacggga
    66241 aaagaaaaaa gacccattga agatcacttt gatgcaaata tcgaattgga aaacaatttg
    66301 cgggaaaagg aaaaaacaga attactcgct ttagttgaag aaacgactca agtcaatctt
    66361 cacttcatcc gtcaatctca tccaagagga ctgggggatg ccgtgcttca agcaaaagca
    66421 tttataggaa atgaaccgtt tgtcgtcatg ctgggggatg atttgatgaa agatgatatc
    66481 ccattgactc aacaattgat gatggattat gaagaaacac aagcttccgc tgttgccgtc
    66541 atgcgtgtac cagaaaatga aacatctaaa tacggaatta ttgatcctaa aacagatagc
    66601 gaaaagggtc gttgcagagt aaaagggttt gtagaaaaac ctgaaatggg aaaagcacca
    66661 agtaatttag ccattatcgg acgttatcta ctgactccta aaatatttga gatattagaa
    66721 actcaagaac caggagcagg aaacgagata cagctaacgg atgcacttca gactcttaac
    66781 cagacagagg cggtctatgc gagagagttt aaaggaaaaa gatacgacgt aggcgataag
    66841 ttaggatata tgaagacaaa tattgaatat ggacttcaac attcggaaat tgggacttca
    66901 ttaagtgcat atattatcca gttgagtaaa aagctaagaa cagaaagtta actggaaata
    66961 agtggcctgc tgagaatgaa aggctatttg ttattaaagc ggcagcttgt gcgtcatttg
    67021 cgcaactgtc gttttagttt tttgactcta gatcagttga gtcgtggaaa acgaaagata
    67081 gaaaaagact ttcgtgaata gattcagaaa atattatgct aatggtttaa ttttttttta
    67141 agttgtataa aagaaaatga ttacataaga gaaatgaaag ccaagccaga agattcatag
    67201 tagaataaaa aggcgaattt tttaattata aaaaaaggtg tgtgttcact atgggaaaat
    67261 tagtcgctgt tgcacagtcg ctgcttgata tactcaagtg gctgatggaa ggaagcaatt
    67321 ggatatttgt gttgccacta ttgcttatta gtctatttat catgtttcgc atggtcagaa
    67381 aaaaagaaac gtttctgatt tttatctggt atgcagcatc cgttggggtt gctaccttga
    67441 tggttgaatt ggcgttaggt agttgggaag cttgcgtatt tgctttattt tttgctgtac
    67501 tgtatctaat catttatatc ccatatatga aaagaaagtc tcggataggc agaaaaggta
    67561 gacatacaac tactttttct agtacagatt ctctcgaaca aagtagaaga acgagaagaa
    67621 gacggtaata tttagtaggt atacgcaaaa aaagataaaa taatggataa actattgaga
    67681 tgagagattt atttaattgg tggaaaaaag cttttttcac ttatataaaa gaatcttttt
    67741 taaaggaatg cttgttgtat cgggataagc cattcctttt tttatgttat ttatatatat
    67801 ataaatcata ccaatgtttt tttgtatttt cttgcttgca cttggataag agattactta
    67861 caataaattc agatagaaac agctgaataa aaaaaggctc cctgaccctt agttggcgct
    67921 aagaatcagg gaatgaccag tcacacacat acaccctgac cgatcatttt gccatagtca
    67981 atgcagtgca tcgacctaat ttattgtacc taatctaggg tgaaaattct acccctatgt
    68041 agatattttc catggtctgc acgttgtttt atttgctatg tcaaggtatt gggcgtattc
    68101 gttcaatgcc ttttttgtgt ttgaaacagc aaagaccaca tgtgttactg tctaactact
    68161 gtttttttat gtacttcctt agattaggca gctgtttcta ttcatgtcaa gtatagctag
    68221 gcgggagaga taaatgagtt tatgttattt tgactattat caccaattgg aagagaaatt
    68281 aaggatagaa gagccgctga tgcttcaagc tggcacttgg atcgcgaaac aaattaatca
    68341 aggtggtaga ttgcagatat atgctagccg cacactaagt ggtgtagcat ttgaattttg
    68401 ggatcaaacc ccggatcttg taccaagtat attgattgaa aatccagccg gaggtgtcta
    68461 tgaaacgcta gaaggtgcag gacaggcaat tattgatcag ctttctgtca aatcagaaga
    68521 catttttctt cttctttcga atgaaggaag aaacccggca atcatcgaac tagctcagtg
    68581 gatcaaagaa aatggtcatc cattaatcat tgttactgga tttgatttgt cacgaagtat
    68641 caaatcgcaa catagcagtg gtttgcgatt atttgaattt gctgatttgg ttttggacaa
    68701 ccacgccaat ttacatgatg cagtcttgac tttgccaaat ctagatccag cgatctgcgg
    68761 aacagcctct cttgcaacga tctttttgct gcagcaagtt ttgtatttta cagcaaaaca
    68821 gctagtccag gacacaagtg gaaaatagtt atccacatgt tgacaaagtt ccttaaaaaa
    68881 ataatgttcc acataaaaat ggagcgtttg aaaaaaagaa aacgattatt aatgaggatt
    68941 aacaacgact actttttttg ttttagttat tttaagatgg atcatctttg attttaagct
    69001 tgttttgttt aaagtttgtt atttttataa gttgtttcac agttatgaga aatgagttat
    69061 aagaatatgt agtgtcagaa aaataaaaag tagtggaaaa agagacaaga aagaatccat
    69121 atggattctt tcttgtctct taatacacgt tgatgaaaga gtcttcccca aaactcttta
    69181 caaagtaatt atagtacatt tgttatcatt attgcaatga agtttacctg atataacaaa
    69241 attgtccaac aggatacctt tttctaatag aaataaaata cacaaaaatt gaaggataga
    69301 taatggatat ttataagtgt ttattatttt ttttgcaatg aaattcaatt tttcaatgat
    69361 tgtaaaatga aaaaaacagg acgagatttt ctctaatcta aaaataaaaa aagaatttta
    69421 aggaaaaaca gagaaataaa atacttaata taaatggaaa gagaaaaaaa taatcataca
    69481 taggagaaaa aaaacaaaat agaaaaaagt gattttctaa taaattattc atgtggaaat
    69541 gtcattttta ctgtataatt catttgatta tccatttttt attcatcaaa attactgaaa
    69601 aaagaaagga agaaataaat ttgaagaaaa caaattcttc aggaaaaccg aaacgcgact
    69661 tcactaaatt atcgacaccc catacgtatg tcattatttt tggtgtagtc atctttgcat
    69721 ggatactgac ttttgtcgtt ccagcaggaa agttcagcac gcaagatatt gaatacaaag
    69781 atgcaaatgg cgaaacaagt actcgtactg ttttacgtca agattccttc cgttatgctt
    69841 acgagctgga taagtcgtat gtgtttgatc aattagaaga actgcaagat catccagcag
    69901 aacgtgaaaa actggatgtt ccggaaaaag gattggaaaa agtcattgct gacggagaaa
    69961 aaaatcttac gcaggaaaaa ctagatgaaa tctccttgac agatgatgtg ctttacgatc
    70021 agtacggcga aaatatctat gatacttcta aaaaattgca taaaacagcc aaaatatggg
    70081 gaacagatga ttttggcggc tttggtttct taaattttgt ttttgaagga ctagtatctg
    70141 gagataagta tggatctgct gtagggatcg ctgcattgat ccttgttgtt ggaggtgctt
    70201 ttggtattat tatgcgtacc ggagcgatcg acgcaggtat ctatgcgttt atcagtaaaa
    70261 ctaagggact ggagcgttta gctttaccgc tattattctt tgctttttca ttcggtggcg
    70321 ctacattcgg gatggcagaa gaggtaattc cattctcaat ggtgatggtt ccatttgtca
    70381 ttgcgttagg atatgactcg atcgtagcag taaccgtgac ttatgtcgca tctcaagtcg
    70441 gaaatgcgac ctcttggatg agcccgttta gcgtagcggt ggctcaaggg attgctggaa
    70501 tccccgtgtt gtctggtgcg acattccgat tgattatgtg ggtagttgtt actgcattag
    70561 ccgctggtta tatgatgata tatgcagaaa aaatccgtaa aaaaccagaa agttcgttga
    70621 cttacaaatc agatgattat ttccgttctc atatcaaaaa gacatctgat gaaaataaaa
    70681 aattcatgct tgggcataaa ttgatcttat tagagatgtt agttgtcctt gtctggatcg
    70741 tttggggcgt gactcaaaaa ggctattaca ttccagaaat cgcttctcaa ttctttgtga
    70801 tgggattagt tgctggaatc attgctgttc ttttcaaatt agatggaatg aaagtcaatg
    70861 acatcgcttc ttctttccaa tctggtgcag ctgatttagc tggtacagca atcgtagtag
    70921 gtatggccaa agggattctt cttgtcttgg gaggatctga tgcatctgtt ccttcagctt
    70981 tgaatacgat tttgcatggg atcgggacgg cgttgaccgg tgttccagct gtcattggtg
    71041 cttgggcgat gtacatcttc caaagtttgt tcaacttggt tgttacatca aattcaggac
    71101 aagcagcttt gactatgcca atcatggctc cactggcaga tttagtaggt gtatccagac
    71161 aagtagcagt tcttgcttat cagcttggtt caggttttat ggacgctttt acacccgtat
    71221 cagccagctt gattggtgtg ctaggtgttg cacggatcga atgggcaaaa tgggcaagat
    71281 tccaaatcaa gatgcaagga ttcctgtttg ttttaggaac tattttcatc atgattgcca
    71341 ttgcaatagg tctgcagtag tactggagac ctgtaaataa aaaagtaatc caaacagtag
    71401 ataaggactc caagaaccgt cattttacgg taaaatcaaa ggagtaaaga tcctatcgtt
    71461 tggattattt tttaagatcc tatcatcagt tatacttaaa gaaagaggaa aaatgtatga
    71521 aaatcattcg acaaattgaa gtgtttgcac cagattactt aggaaaaatg gatgtactga
    71581 ttgccggtgg gaagattttg gctgtagaag aacagctaga aggcggctac gaaggagtgg
    71641 aagtagaaga actttcaggt gagggaaaag tactaacccc gggtttcatt gactgtcatt
    71701 tccatatttt aggtggagga ggagaaggcg gttatcaaaa tcgaacgcca gaagtcacat
    71761 tgagccaatt gactacagct ggtgtaacga cagttgtcgg ttgtttggga acagacggag
    71821 aaggtagaga tatgactgcg ttgatcagca aagcgaaagg tctggaagca gaaggaatct
    71881 ccacttatgt atacgaaggt tcgtaccgat tgccggtaaa aacagtaaca gattctatca
    71941 tcaaagactt tttgacaatt gataaaatta tcggaatcgg agaaatcgca gtatccgatc
    72001 accgttcttc tcagccaagt tttgaagagt tcgctcgtgc agtagcagat gctcgtgtag
    72061 gaggcatgtt atccggaaaa gctgggatca tcaatgtcca cttaggcgga ggaaaaagaa
    72121 agctagagct attgacacga atcgtagaag aaacagaaat tccgatcaca caatttttgc
    72181 ctactcatgc aaatcgcaca ccagaattat ttgaagcttg cgtggcattt gccaaacgtg
    72241 gtggcacgat tgacttcact gctagcgaag atcctgattt ttgggagaag acagatggtg
    72301 aagttcgctt cagcaaagca ctgaaacgat tgatcgagga agatgtttct ttagataatt
    72361 tcacgatgac ctcagatgga caaggaagct tgccttattt tgatgaaaac aatcatttcc
    72421 tagggttagg agtaggaagt gccaaggcat tgctagtagg gatcaaagaa gctgtgcaaa
    72481 aagaaagtat ccctttggaa atcgccttac gagctataac cagtaatcca gcacgtatat
    72541 tgaaattgga taaaaaagga aaaatcgaaa ttggtgctga tgcagatctg tgtatcttgg
    72601 ataaagaaac gcttgatatt gatacagtta tcgctaaagg agaaataatg gtccaagaaa
    72661 aagaagtcaa agtatggggg actttcgaaa aaagttttta atcaacagct ctaactatct
    72721 tttttagaaa acgagcgttc tgtttgtctg tatctgttgt tgatgttacc ctgaaggtag
    72781 atcaataaac aaactaagag gaggaagcac aatggcagat ttaaaaggac gttctaaaga
    72841 tatgaaagat aaagtagtcg gtgaaggaaa agaagcatac ggcaaagcaa cagacgacaa
    72901 gagcaaagaa acagaaggga aagcacaatc actaggtgct gacatcaaag aaaaagctcg
    72961 aaatttaggc gacgaagtca aagacaagtt ttctcgaaaa gacgaaaaaa aataaaaacc
    73021 acttattact aattgaatca agcaaataaa aaatccgaac catatctgcg agacagatat
    73081 ggttcggatt ttttatttga tcattatcct gttttttaaa cttcgatttt ttgaaatttt
    73141 ttatttttta gttcaaagac ttcatcacag ctttttgcta cttcaatctc atgagtcacg
    73201 atgataatac agcgattttg ttcatgggcg atttcttgga aaagtttgac gatatcttgt
    73261 gaagttgttt catctagatt tccagtaggc tcatccgcta cgattagttg atgttcacag
    73321 cagatagcac gaacgatagc gactcgctgc tgctgacctc ccgaaagttt ggtcacctgt
    73381 ttttttgcta atatttcatc aattcctaca cgagccagtc gatctaaagc aacttgtcga
    73441 taattctctt gcttggtctt agtgatttcc attgctgcta tgacgttgtc tagagccgat
    73501 aaataaggaa gcaagttgta agcttggaaa ataatcgaga catcattttt acgataactt
    73561 cttaacccga ttttgttcag tgaacgatct tgatagtata cctttccttc ttttggtgca
    73621 tctagtccag aaataagcga aagaaaagtc gtttttccag aaccacttgc tcctaaaata
    73681 gcgtacattt ttccagcttc gaaattcagt tctacatctt tataaagcgc atcttgcgga
    73741 tcttgatacc aaaatcccaa ttgttctgtc cgtaacatca aattcctcct ttagtttaat
    73801 aggatttttc ttgggtttaa tcttaatatc cctatagaag ctaaaaagac agaaaacaga
    73861 ctgattccaa atgctactcc ggctaatagt cccaattgtg caggtttgac attgatttcc
    73921 aattcgctga cttgatcaga aacagcaaat ggattattcg tggttccttg ttgaccatcg
    73981 cgttgaccgc cttgttcttg tctgttacct ggcatttgtc caccgccagg agcttgctgg
    74041 ttttgtgtcg tggtttctgt ctgttggtca agtagctgct gtcccacggc attcgcgacg
    74101 acgtttccgc taagcgaagc aactcctaat gcaagaatca tacaaatagc cacttcggta
    74161 aacaattgga gaatgatttt acttctggat tctcctaaag atagcaagac gcctaactca
    74221 tgccgacgct cccgaatggt aatcataatg atcagagtaa gtatgataat accggctaca
    74281 gtcactagta aaacaacatt tttagaaaaa cttgccacgt tgtttaaagg ttccaacatt
    74341 gactgataca tggaatcatt tgattgtaag ctaaatgtat ctgtgtcgat cagcttctca
    74401 gcttctttga gaaactcatc cattttatct ggatcagata gagtgtaaat agcagaatct
    74461 atcgtgttat cgtcagatgt cccatttagt tcatttgcaa aagtgtaaga agtgtaaagt
    74521 gtattcgacg gattcatgaa gttgaatttc atacccatac tgccgcttgt ttcgctggat
    74581 tcataaattc ctttgatcgt catttcataa gtggtatctt catcttcagt actcgtgatt
    74641 gtgaaagtat ctccgactgc caggtcattt gtttctgcta gagtagaatc aatgactaca
    74701 ttgtttgtgc ctttgtcgct gtcatctatt ccttcaccat ccgtgatttt tgctgttcca
    74761 tcagaaaaat tactattttg tgcagttgct gacacaccac tgatttgaaa gtctgcttga
    74821 gtcatttgcg gattcccgcc cattcctcca gcaggttcac cgcctgcatc agtagtttct
    74881 gaactgtctt cacttgaatc agaactagtg atggcagtta ttccatcttt tgccatagct
    74941 gaggcggaac tttcaaagga ataactcttt acattatcta attcagctat tttttccgcg
    75001 tccgttaagg aaactggtgt aagagaaaaa ctgcctggat ctggacgttc ttcagtggta
    75061 gaaccgcttg aagaagtttg ttcctgtttt ttaaatgaag cttctcgatt ggcacttaaa
    75121 gtcactgttg ctccaacttc tttttgtgct tgattcgctg cttcttctgc agcgcttcga
    75181 atcgtgaggc cagctagcac aaaaataaga atggctgtga acacggcaaa caataacaat
    75241 gaacgtcccc attttacttt tgtacttttc catgcacgtt tcataaaatt catattttgc
    75301 atccctccta gtagatgcat ttgataatag acaacctatc ttaaagctag cttaaatctt
    75361 atgctgtttg cacaccatca acatgaggtt ctgtatatat aaaaagtcac tatagttatt
    75421 gcaaaaaatg tggtaaaatg aaaaaagtat gtttcaaacc gacgaagaag aaatgaaaga
    75481 ggaatagcaa aagaaatcct agatgctaca gagggatttt tacgtgcata gttgttctaa
    75541 caattgctga tactagcgat ttagtttatt tgttgtataa taatggggaa cagctgaata
    75601 cttatataag tattctggct atagcgtttc gcaaaagatc cattttgtta atgaagtata
    75661 tccaaaataa aatgcccatc caactgtcag aacgcggatg tgctggtaat tttcctgctg
    75721 attctccata agttgagaaa tagtgatttt gcatatgctt cattggaatg gctcatatat
    75781 ttagataaag aagaaaatcg acatctttaa acttggatgt cataagaaga ggtgaagttt
    75841 gtgagtacca ttaaaattat cccattaggc ggcgttcgtg aaaatggaaa aaacatgtat
    75901 gtcgcagaag tgggcgagga tatttttatt ttagattgtg ggctaaaata tcctgaaaat
    75961 gagttgttgg ggatcgacgt cgtaatccct gattttacgt atttagaaga aaacattgat
    76021 cgtgtagctg gtgtcttttt aacacatgga catgcagatg cgatcggggc acttccttac
    76081 ttgttgtcaa aaatttctgt accagtattc gggacagagt tgacgatcga gttagcaaaa
    76141 ttgaatgtca gtcgtaatga agcagccaaa ggatttaagg atttccatgt ggtagatgag
    76201 catacagaaa tagactttgg tgaaacagta gtgagctttt tccgtaccac tcatacgata
    76261 ccagattcag tggggatcaa tctgaaaaca aaagaaggta gtatcgttta tacgggagat
    76321 tttaaatttg accaaacggc tatcccaatg tatcaaacag attatgcacg attggcggaa
    76381 atcggcaaag aaggagtctt agccttacta agtgaatcgg caaatgcaga aaatcctcag
    76441 cctgtagctt ctgaagccca aatagcagat gaagtatttg atacgatcaa atattgggaa
    76501 gggcgtatca tcgtcgcttg tgtagcaagt aatttgcaac gagtgcaaca agtattggat
    76561 gcagcagaaa aagcacaacg aaaagttgtc ttgactggtc aagatttcga acgaattatt
    76621 cgcacagcga tgcgtttaga aaaacttcaa ttaccaagtg aagatctgct tgttacgttg
    76681 aaagacatga aaaactatga tccagaagaa ctgatcattt tagaaactgg ccgaatgggt
    76741 gaacccatca agtctctgca aaaaatggca aacggtacac accgtaatgt caagattgaa
    76801 gaaggagatt tggtttatat cactactacg ccaagcatcg cgatggaaac catcgtggcg
    76861 aaaacggaag atatcattta tcgagctggt ggaacagtga agttgatctc tgagaatatg
    76921 cgcgtttctg gccatgccaa tcctaatgac ttgcaattaa tgatcaattt gatgaaacca
    76981 acatattttg tgccagttca aggagagtat cgtgaattag ctgctcatgc agatttggct
    77041 catgcagtag ggatgccata caaaaatatc tatattactg gacgcggaga cgtgctggaa
    77101 tataagaaca agcgtatgag tgttgcagga actacaagtg cagaaaatgt aatgattgat
    77161 ggattaggca taggtgatat cggaaacatt gttttacgtg atcgaaaaat cttgtcagaa
    77221 gacgggattt tcgtagcggt tgtcactatc agtcggcgag aaaagaaaat catttcaaaa
    77281 cctcaaatta cttcacgggg attcgtttac gtaaaagcta gccgtgatct gatgaaagaa
    77341 agcagcaata tgattgaaac aatcgttgag aaacatttag aaagcaatga ttttgagtgg
    77401 agcaaattaa agcaagacat ccgagatcaa ttaggccgtt acttatttga acaaacaaaa
    77461 cgccgcccag tgatcttgcc agtcattatg gaagctactc aacgtcgaaa taaaaaataa
    77521 acaaaaagag taagatgaac ctctctatag agtgctcgtc ttgctctttt tttgcgaaaa
    77581 acaaataatt tttgaataca gcatccctcg ctttataata aacgatagaa taaagggagt
    77641 gaatcaatga tgagtcaaac aaaagtcgaa cgttatttag aagaacaaaa gatcagctat
    77701 caaccacttg attttagtca tgtggtagaa gaatctttca cagaagaact acaaaaaaga
    77761 gggattgatc cagctttgat atgtaaaact ctcgtagtga aaggaaacaa aactggggtg
    77821 atcatcgcat tgattccttt gaacgatcac ttagattaca aaaaaacgag acaagtgacg
    77881 aaagatcgta aagttggttt tcctggaatg gattttgtat taatgcatac aggatatccc
    77941 cacggagcaa acacccctat tggaataaaa ctcgcacatc ctgattattg ttttttagca
    78001 gacagttctt taaaagaaaa agaagaagta attgtgtcaa gcggtgaaat cgggagaagc
    78061 cttcggataa aagtagccga tttagaaaag atcgtccatc ctatttacgc tgatttaatt
    78121 agttaaggga cgagaagaga agctaagcag agcagagacc tcaaacttga gattatatct
    78181 gcttggtact tggtgcatcc tgtattatct gttacaattg ctttgtacat actgtactat
    78241 caatccaatg aaaatatatt tagcagctat attttttcat tgatgtgcaa gtgatgaaat
    78301 cgtttttaat aaaaaagata cagagaaaac gcgaggtgta aaatatgaaa attacgtatc
    78361 atggacattc ctgtttaaca attgaaatgg aaaatggcca acgcgtgatg attgacccgt
    78421 ttattacagg aaatccattg acagacttaa ctgcagaaga agtaaagaca gattggttgc
    78481 tgattactca tggtcatagt gaccacatag gagatatgat tcctattgca aaagaaaatc
    78541 aagccacaat tatcagtatt gttgagattg ctgattatgc gaacagcaga ggagtagatt
    78601 cattcggtat gaatatcggt ggaaaacatg cgtttccatt cggcgtggta aaattcgtac
    78661 atgcacagca tagttcaagc tatgaagtag acggtatcgt tcagtatatg ggcgagccta
    78721 gcggaattat tattcaagca gaaggaaaaa cgatttatca tgcaggggat actgcttatt
    78781 tcagtgatct aggattgctt gcagaagaat tcgatattga tgtcgctttc ttgccgattg
    78841 gcgataacta tacgatgggg ccagaagatg cagcaaaggc tgcgcaaaca attcgtgcca
    78901 agaaagtagt tccaatccat tacaatactt tccctgtcat tgaacaagat cccgaatctt
    78961 ttgtagagtt actggaagat agtgaaggaa aaataatgag cgtctcggaa acgctggaag
    79021 tgtaggcaga aaatggcgac aaaacatgat ttgattttag aatatattga aagtttacct
    79081 gttggcaatc gaatttctgt aagaagcatc gcaaaagaat tgaatgtcag tgaaggaaca
    79141 gcgtaccgtg caatcaaaga tgcagaaaat gtcggactag tttcaacaat tcaacgagta
    79201 gggaccatcc gtatcgaacg caaattaaaa aaacatattg aacgtttgac atttggcgag
    79261 gtcgtcagga tcattgaagg ggacgtttta ggcggggcgg caggattaga caaggtcttg
    79321 aataaattcg tcatcggcgc gatgactaaa catgccatgg aacgctatat tacgccagga
    79381 tcactaatga tcgtcggcaa ccgggcggaa gtccaaaaat tagcattgga agatggcgcc
    79441 gcagtattga tcacaggagg attcaatacg actgctgaga ttgcaaagct agctgatgat
    79501 cttgaaatgc cgatcttacg cacctcttat gatacattta cagtcgcaac catgatcaac
    79561 cgagcgttaa gcgaccaatt gatcaaaaaa gatatcatgc ttgtcagtga tatctatatg
    79621 ccagctgaaa agactcatta tttgcagcag acagatacga tttctgatta tcagcgtttg
    79681 tcagaagaaa cgcagcattc gcgttttcca gtcgtcaacc gccatcatcg tttgatgggg
    79741 attgttacgg caaaagatgt tttagggaaa tcgccaaacc agatcatcga tcgggtgatg
    79801 acgaaagaac caatcagtgt aaagaaaaca atgagtattg cctctgttag ccatcaaatg
    79861 atctgggatg ggctagaagt catgccggtc gtttccgatg acttgacatt ggaaggcttg
    79921 attacccggc aagatgtaat gaaagcgatg cagcttgtcc agcgacaacc gcagattgca
    79981 gatacgattt cggatcagat atctggaaat atccatacga ttgatactga ccgtgaagga
    80041 aatcgtttgg aaaaccctaa gttcaaattc gtagtagcac cacaaatggt caatggcgtt
    80101 ggaaccattt cttttggcgt acttagcgaa atcatttctg atgtcgcaca aaaaacaatg
    80161 gtgatgaacc aaaaacgaaa tatcttgatt gaacaagtga acctacatta tttgcggctg
    80221 atccaattgg aaagcgaatt agacattcgt ccacgtgtat tggaaatcgg cagacgttcc
    80281 gctaaactgg atatcgaagt gtttattgaa aacaccatcg tttccaaagc aatcgttgtt
    80341 tgtcaagtaa tggaacgttc ttagaaagca ggagtgaaat gacagtacag caagaaatag
    80401 tagatacaat aaaaaaatac gataaaatca ttatccacag gcatttgcgc cctgatcctg
    80461 atgcattagg atcacaagta ggattagccg aactattacg ggaaagtttc ccagaaaaag
    80521 aaatacgtca agtaggtgaa acgattgaag ggcttcgctt tttagcagaa atgcaagaag
    80581 ttgaagatgt cttctaccaa ggagcgctag tcatcgtgac tgatacagct aattcaccca
    80641 gaatcagtga tcaaagatat cagttggcag aaaaactgat caaaatcgac catcatccca
    80701 atgatgaccc ttatggagat cttgtgtggg taaatacaaa agcaagtagc tgtagtgaga
    80761 tgattgcaga atttgctttg atgtttcctg aatctttaaa gatgaacgtt aaggctgcac
    80821 ggttacttta tgcaggaatc gtcggagata cagggcgctt tttgtatccc tccacgacgt
    80881 cccgtacatt agagattgct tcgatattga gaaattatcc atttgatgca agtgctttga
    80941 acagagagat tgaacaaatg ccgatgaaag tcgctaaact ttccggttat ctttatcaaa
    81001 atatccaggt ggatgaaaat ggtgcaggaa gaataatcct tccgcaagaa attcttgata
    81061 aatatggaat cgatgattca gagacagctt cgatcgtttc acttcctgga gtgattgacg
    81121 aagtgctggc ttgggggatt tttgttcagc agccttcagg gtattaccgc gtacgtttac
    81181 gttctaaggg gccgatcatc aatgaattgg ctaaacgcca tcatggagga ggccatccat
    81241 tagcaagtgg tgcgaatgca aaagatttag cagaagtaga ggaaatctat aaagagatcc
    81301 aagatatatg ccaatcgtat aagagcagaa aaacagaatg atacttcgtt cgaaaacgtg
    81361 ccttttgtag taaaaatcac aaatgtatct tttcaagatc ttctttttcc gttacaatag
    81421 tgctcactaa agattttaaa ggagaaagaa gatgacatta ccaaattgcc cagaatgtgg
    81481 ctcagagtac acatatgaag atcgaggctt gttgatttgc ccagaatgcg ggaacgaatg
    81541 gaacaaagaa gaacaagaaa ctgtcataga agacggatta gtggtattag atgcaaatgg
    81601 aaaccgtctg ttagagggcg atagcgtgac agtgattaaa gacttgaaag taaaaggtgc
    81661 gtcaggtgcc attaaacaag gaacaaaagt caagaacatc cgtttagtag aaggcgatca
    81721 taatatcgat tgcaaggtag aaggatttgg accgatgaaa ctgaaatcgg aatttgtgaa
    81781 aaagaattaa agaatattca aggtcttttc acattctttt cctactacta atgataaaat
    81841 aaagtaaacg aaaaggagtg aaacgaaaat gtatggttat ggaatgtatg gttttttaga
    81901 tccgacattt cttttggtca ttcttggatt agttatttcc ggaattgcgt cagcgtacgt
    81961 caatagtact ttccgaaaat acgatcaagt gagaagcaaa aacaatgtga ctggtacaca
    82021 agcagcacaa tatatattac aaagtcaaca gataaataat gtcggtgttc aacaaattgc
    82081 cggagatctc acagataact acaattcagg taataagatg ttgagtttgt ctcaagcaac
    82141 tgcacagtct acttcagttg ctgcgatagg tgtagcagct catgaatgcg gacatgcggt
    82201 acaagatgct tcgggttatg tcccattgaa gattcgtgca gcacttgttc cagcagctaa
    82261 ctttggttcg atgatttcgt tccccttgat tatggtaggt gtattgctta gctggaactc
    82321 tacgttaatc aatatcggga ttttcgcttt ttctttagca ttacttttcc aattggtgac
    82381 attaccagtc gaatttaacg cgtctcggcg agcaatccaa attttgagtg aaggcggact
    82441 actgacggaa gaagaagtac cgatggcaag acacgtatta tttgcagcag cactgactta
    82501 tgttgcagca gcgctttcga cattcctgca gctgttgcgc ttgatcttat tgttcggcgg
    82561 caaccgaaga gattaaaata aagaagttgt gaaatcagcg ctttgatctg agctaatacc
    82621 gagagttagc tgattgaata ccatttattt ggaataagag gatgtgacaa gaattttgtc
    82681 acatcctctt tgttttgttc tcataacctt ttttcatata cagttcatga accgctttta
    82741 ttaacttgcc aaataacact gtattgtgcg ttgtatccag atagaaagtc tccgtttcat
    82801 ctgaaatttt ctcatgctga tctgtaatga tcaaatcagc atgttctgaa tatgcggtaa
    82861 ttttaacagc atctttgcga aataactgct gcaaatggct ttgaagatga taatttcctg
    82921 taaactgttt ggttatctgc aaatggatga gtaactgctc tttcgtttct gtttgtagta
    82981 agtgttggat caattgacta aggtattgac tgatttggtt tctttcccca ttttttgaaa
    83041 aaattgtatc gattttttct cttaatttct tttcctgtat aaaagaacta gaatgattgg
    83101 acgtggcttc tggaaagcaa agtgtagaaa aactactgct ggattcaccc aacagttcga
    83161 aaaaaacaac tgccaacaca agaaaataaa aataaattgg tattttattt tctaaatggt
    83221 tgagaggaaa ctgttgagtt aagtaagtca tcaattgacc gacttgtcga caaataaggt
    83281 ttttgcttgt ggaaaataaa aaaccaatct cctgtttttg tcgaaaagag atttgatttg
    83341 gaaaaaaaca atagaaaaaa taattaaagt aggctctctc tgtttctgtc tcttcacaag
    83401 ggcgactcac tgaaaaagaa gtaaagtatt ctgaataatc atgtgtatgc tgcaataagt
    83461 ccatcaattc agtgatttca gaagaagttt ttggaaaata tgcctgttgt ttgtttcgta
    83521 atatgaataa agttaacagc aagtagatat ttttttcttg ttttgaaatt ttttctattt
    83581 gctcatctgt actgttcatt tttagtgcat ttaattcaag tgaggaaaat ggccaatcgt
    83641 tacctccaaa tgtatctgaa agaaaaaagt aaagatagag acggatagat aactcatttc
    83701 cttcaagagt acagcaattt tttacagata ggatccgtaa atggaatttt tttaaggaat
    83761 gattgagctg ttttgtcagt ttttcgagat aggagggcga tatataaagt tgttcaagta
    83821 aatatttttt tggtacagca gtttgtggat aattgattag taacatcaaa tagttaaaac
    83881 gattggattc ttttaggtag cataatttta acttagaaaa aacagctaac tttttagttt
    83941 gatcggtttc tttggtttgg atctctcctt tatgattaga ataaataaat tcatcaatca
    84001 ataaaaattg cttgagtgat acatttattt ttcggatcag ttctttgatt gtccgttttg
    84061 gaatatgtaa gtcattggat aattcttgta aagaacaatt atttttttga atgaccattt
    84121 gtagaacaag taactctttt tttcttgctt caattagcat aaatacctcc tttttattct
    84181 gtttttgtat atagttagac aaaaactgtg agtggaaagt catttcagtc tgtgttattc
    84241 tcacagagtg tcgccttctt ttttatataa cgttatttaa tttttttgtt accttgttta
    84301 ttctattgtt tatttcctag ggtattttgt caagatattc ttgtttttaa ggcggaaaaa
    84361 ttgattttta atggatataa ctaaatatgt tttgataatt atcaataata tttttagaat
    84421 tatttatgtt atttatttat gggtagatga aaagagacgg aggtaagaat gatggggaga
    84481 gtaacaaatt atagtaaaga atatttgctg ttcaaaagta tggtatacgt ggaagaatat
    84541 ggaatgaagt caattactgc aagagagtta gcagagttct gcggttgttc tacatacccg
    84601 atttatacac atttcaaatc aatcagcggg ttaaaagaga agatattaga agaaatcact
    84661 gtttattttg aaaactactt agctgaatgc agttccgatg atgttttaag cattgtctac
    84721 ttattgaaag attttttttc tatccatgaa agtattcgtg aaatcattgc aaaatctgat
    84781 ttagacatgg attcgctatt taagcggcca tttttctcat atgtcaaagg tcacacgaag
    84841 atcaaagaag aaaagtcgct tgaattggta tggcttaatg cattgggaag tttgcgctca
    84901 gatgattctt ctcaagattt tcttgaaatg atgaacgctg tttgggataa aaacgaggtg
    84961 acggatgaat acttggaaaa tatcttaaag gaacagtcac cttaggcagc aacatgaaaa
    85021 agtagatcag ccacctttat ttttcgtaaa aaagattgta aaatgtctaa cgaaacattg
    85081 gaatgaagga ggaagcgaca acgttaccac agcaatttat caaaaaatat cgtcttcttt
    85141 taggcgaaga agcatccgat tttttttctg cgcttgaaca aggaagcgtg aaaaaaggat
    85201 ttcggtggaa tccactaaaa ccggcaggat tggacatggt ccaaacttac catagcgaag
    85261 aattacaacc cgctccctac agcaatgagg gatttcttgg cactgtcaat ggaaagtctt
    85321 tcctccatca agctgggtat gaatatagcc aagaaccaag tgcaatgatc gttggaacag
    85381 ctgctgcagc aaaacccggt gaaaaagttt tggatttgtg tgcggctccc ggtggtaaat
    85441 caacccaatt agctgctcaa atgaagggga aagggttatt agtgacgaat gagatctttc
    85501 cgaaacgtgc gaagatttta tcagaaaata tagaacgatg gggagtttcg aacgcaatag
    85561 tgacaaatca tgcacccgca gaacttgtcc ctcatttttc gggctttttt gatcggatcg
    85621 tggttgatgc tccttgttca ggagaaggaa tgttccgaaa agatccaaat gcaataaaag
    85681 agtggacaga agaatctccg ctatactgtc aaaaacgtca gcaagagatt ttgtcttcag
    85741 caataaaaat gctaaaaaat aaaggacaac tgatttattc gacttgtacg tttgcaccag
    85801 aagaaaatga agagatcatt agctggcttg tagaaaatta tccagtaacg attgaggaga
    85861 ttcctttgac tcaatccgtt agttcaggac gttctgaatg gggaagcgta gctggtttgg
    85921 aaaaaacaat acgtatatgg cctcataaag atcagggtga aggacatttt gttgcaaagc
    85981 tgacttttca tggacaaaat cagatgcata aagaaaagaa gacacgaaaa aaaagtaaag
    86041 tgcaaatgac aaaagagcag gaaaaactct ggacggagtt ttcaaatgat tttcattatg
    86101 aagctactgg aagactttta gtgttcaacg accatctttg ggaagttcct gagttagccc
    86161 cttctctcga tggtttaaaa gtcgtacgta caggtttgca tttaggagat ttcaaaaaga
    86221 atcgatttga acctagctat gcattagcgc ttgctacaaa aaagatagag aatatacctt
    86281 gcttgccgat cactcaaaag gaatggcaat cttacacagc aggagaaaca tttcaacgtg
    86341 atgggaatca aggatgggtt ttgctagtat tagataagat acctgtcgga tttgggaaac
    86401 aagtaaaagg aacagtaaag aactttttcc ctaaaggatt gagatttcac tgagtggatt
    86461 agttcgttta tttttttgtc tatgctatga tggagataga taaaaaggag ctgatactta
    86521 tgaaaacatc aacaaaagta acaatcggat taagcgtagc agccgctgcc agtgtagcga
    86581 cagcagtcgt tgtatcggga aaagtaatgg aaaagatcca tcatatgact actcggacga
    86641 aagtaaaaaa attcgtctat gacaaatttg atggaaatga aaaattacta gaaatcgtag
    86701 atggtctttc agatagtgac ttggattctt tgatgggaat gttagcaaaa atcaaatcag
    86761 gaaaaaagaa aatctctgtt tatggtgatt caatcaaaga ttcaaccgaa gatgtaaaag
    86821 accggctaat gcattttgtt gaaaaaatga tgtaagagaa actagctttt gaacactatt
    86881 cattcgaaat aaggggttgt gacaaaatta ttgtcacaac ccctttaatc tatctttaat
    86941 tatgttcatg aagcaataaa agatagcaaa acagtaaatc gttggctttt tttagattga
    87001 aaccagactg ttcttgaaat ttttcgattc gatattttag agtattacga tgaagaaaca
    87061 gtgtttttgc agcagagctg acattgccta attcattcca taattcttga atgatcactt
    87121 ccatttcatt ttgtttgatc agttctatgt aacttttgat caacttacta tcttttacag
    87181 tatcttttgt atagtaatgt aaagccacat cttgcataga aaaagtacgg ctgtgagtat
    87241 aaagattgtt ttgctctgtt aaaaaaattt ttctttcttc agcaaacaaa gggacgaggt
    87301 cggtgccagg tgaatggaaa gaaccaacga atacagacgt tgtcgtatca aaatcagcat
    87361 ctaaagatag aaaaataccg ttgatttcag tagcatcaag ataatcacgg tttatttgtt
    87421 cgactaagag cgcatctgtg tctgtataaa aaaagaaatc agcagaatag cgaaataatt
    87481 ccaaaatagt atcttgccat tcttttttta agaattctcc ttttgattcg acgtgaagct
    87541 ggatcaaacg aaagcttttt tcttgaacac aagaagcatc tttaaaaaga tagtgatacc
    87601 atgggtgttt tttttgatcg ttgattacag ggaataacgc tttcaaaagg ctggtttctt
    87661 gttgagataa tgaatcttgt ttgatccaga taaaagcatc atcaattgca aaagaaagga
    87721 tatccgcttc tgatgctgga gagttttttt tctgtgcttg tgggtaaaga gcaagtaatt
    87781 tatccatttt catcttgttc acctcttgta tttattttac catagaaaaa aaagttagtt
    87841 acagcctttt tatcatatgc taaagtaaaa caagaaaaaa caaaggcagg gaagggtaat
    87901 tggtaaatac aaatcttgat gcagtagaaa aagaaaaatg gatgcgcctt gcattggcag
    87961 aagcaaagaa agcagaaatg cttcatgaag ttccgattgg agcagtggtt gtattggatg
    88021 gaaaagtgat tggaagagga tataacctta gagaaaccac gcaagatgct actacacatg
    88081 cagaaatgct tgcaatcaag gaagcctgtg aaaaagtggg aagctggcgc ttggaagatg
    88141 ctgcactttt tgttacctta gagccttgtc ctatgtgcag cggcgcgatg attttgtctc
    88201 gtgtagcaga agtttatttc ggcgcgtatg atccaaaagg cggaacagcc ggtaccttga
    88261 tgaatctttt ggaggacgag cggtttaacc accaagcata tgtagaaggt ggcattttag
    88321 aagacgaatg tgggatgatt ttgactgact ttttccgaaa gctccgccag cgaaaaaaga
    88381 aattaaaaaa agactggtca acgaatgaaa aataaggtat actattcttt gccgaaaggc
    88441 taggacaatg gtgggcttgt gaagcgtgtc aggtctggaa ggaagcagca ctaagcaggt
    88501 tccgccatgt gtctgattat aatgaaacga caacagactt tcgggtctgt tttttttatt
    88561 tttatagtac tgtaaaaatg aatgttcctg attttttagc cagactgatt tatcgaatat
    88621 tgtacttata caatttgctt caaggcagga aaaactctga aatagagctt gtttcaatgg
    88681 aagaaaaagc tgcctatggt atgataaaga taaagagagg cgagagggta catggaaaaa
    88741 atagtgattt tacatacgaa tgatctgcat tctcatttag aaaattggcc aaggatcaga
    88801 aggtttttgg atcaacgtaa acgagaaaac gaaaagaaag aaaaaacgac aacgattgca
    88861 gtagatctag gtgattttgt ggatcgttgg catccattgt cagaagcaac gaatggacag
    88921 gaaaatatct tgctgatgaa tgaagttggt tatgatgcag cgacgatagg aaacaatgaa
    88981 ggcgtaggaa attccaaaga agagttgaat catttatacg atcatgctga gtttgatatc
    89041 atcctggata acttattcga taaaaatacg ctccagccac cggcatggac gaaaccatat
    89101 aaaatcatta caacgaaaca ccagacgaaa atcggactaa ttgcatttac tgctccattt
    89161 ccgcttactt ataatccgaa tggctgggac atacggaatc cttatgatat tttgccagaa
    89221 ttagtcgaag atttacgttc acaagtggat gttttagttt tgatgagtca tctcgggatt
    89281 caggatgatt tccaaattgc aaaagaaata ccagcaattg atgttatttt aggatcgcac
    89341 acccatcatt tattcagaga aggtcacgta atcaatgatg tccaaatagc agccgctgga
    89401 aagtacgggc agtatgtcgg tgaagtccat ttaaccatcg atgaagagaa aaaaatcctt
    89461 aagcattcag ccaaagccat ccctaccgaa acaatgacag cttttacaga agatgaacaa
    89521 gaaataaata gttatctaga acgtgggcat gaattattaa aagaaaaaga agtagcagat
    89581 ttgccatttt ctctgagtct agatatcttc aatgagcatt cgtttatcca agtagccttt
    89641 gaggcggtga aagaacgagg aaagacggaa gcagcaatat taaacagtgg tctgttttta
    89701 actgaaattc caaaagggcg ggtcaatcag gatcagcttc acactgcgtt gccgcatccg
    89761 atgcacttgt taaatgtcac attgggtgga aatgatctga tccgcttagt tttagaaata
    89821 gaaaaaaatc gtaacttttt acgtaactat cctatgaagg gaatgggatt tcgcggtaag
    89881 atttttgggc agatggtcta taatggaatc acatatgatt ctattaacca tcaagtcttt
    89941 tggaagaaca agccaatcga tctgaataaa aattatactt ttactaccgt agatcatttg
    90001 atgtttgttc cattttttcc aacgattgag attgctggaa aaaatgaatt tttgttccct
    90061 gaatttatcc gaagtgtggt aggagattac ttgaaagctc actacccaat caaataaaaa
    90121 caaggtataa taaaaaagat aggtggtgaa cgcatgtctg caaaacaaaa tgaacagcag
    90181 aacgttgagc ataaaacaga aattgctaag aaaaaatcat cagctgaaca ggaaacaaca
    90241 gtcaccgaag aactgacagc tgctttggaa gaaatcgttg aggagcctaa agcagaaaaa
    90301 gtcaaaggcg agctagtgac actgttagat gacagtaatt ttttgatagg tgaaagacat
    90361 tatcggcttg tgtccgatta tcgtgaagga tttaatgcag aaaagcttgg agaacgttac
    90421 agtgatgtac tagcccgata tgattatatc gtaggagatt ggggttatga acaactacgc
    90481 ctaaaaggat ttttccaagc ggataatcga cgggcgcatc cagatcagcg aatcgattcc
    90541 ttggaagact atctttacga atattgcaat tttggttgtg cgtattttgt catcgagaga
    90601 atcggcggta aaaaagaaaa gacaactcag cgccgaaaaa agaaaaaaaa ccataatcgt
    90661 gcgtatatcg atgagaaaaa aggaccagtc gcatctaatc gcaaaaaacc ggttattaaa
    90721 aatcgaaaaa cagagtcagc aaaaacctct gaaaaagtaa aaaaacaaga acaacctaaa
    90781 caagtagaaa aaacaaaaac agcatttacg atcagaaaaa gggaagagta gtggatgaat
    90841 ggactataaa ggatatttaa ttgatttaga cggaacgatt tatcgtggga cacaacccat
    90901 accggccggt aaacgatttg tggaagaatt gcaaaaaaga aaattacctt tcttgtttgt
    90961 taccaataac acgactaagt caccagaaac agtagctaat cgtctagcag atgagtttga
    91021 cattcatgta gctccagaga cagtctacac agctactttg gcaacaatcg attttatgaa
    91081 agcagatgga aaagggaaaa aagtctatgt tatcggagaa gcaggattga ttgacttgat
    91141 tttagctgcc ggatttacat gggaagaaga ggctcctgac tatgtagtgg taggcttaga
    91201 taattatctg acctatgaaa aagtagttaa agcaacactt gctattcaaa aaggtgctac
    91261 tttcattgga acgaacccag ataagaatat acctactgaa cgcggccttc ttcctggagc
    91321 agggtcagtc atctcttttg tagagacagc aacccaaacg ccgccgatct acatcggaaa
    91381 accagaagcc atcattatgg ataaagccgt tgaagtatta gggctgcaaa aagaagaagt
    91441 aatcatggtt ggagataact atgaaacaga tatccaagct gggatacgca ataatataga
    91501 tactttgctc gttttatcag gttttacaaa agaagaagat gtacctgggt tgcctatccc
    91561 agctacctat gtgaaacaat cactggatga atggagcttc taatatgaaa aattcgagat
    91621 ggcagtggat ggaatatgct ggattgttca gcctatttct gacactgatc agtctggcag
    91681 ttggtgtgac gatcaacttt cgaccactat acgtatttga tatcggacat ttgcaaattt
    91741 tggattatac ttctttagat caagagacgt tactgaaaaa ttttgatcac ctaatgaatt
    91801 atctcaataa tcccttcaaa accatcctca gcttgccaga tttcccagtt tctgctagcg
    91861 gagcccatca cttttatgaa gtgaaaattt tgtttttagt ggattatgct gtgtttttca
    91921 tcactttgat cccgagtatt ttgtttatca aatatttgca aaagaatgat cggctttggc
    91981 ggttgattcg tccgtttcaa atcggcatgt tactgccagt tgttttcggt tttttcatga
    92041 tgataggatt tgatcgcttt tttatccttt ttcatgaaac gtttttcaac aacgatgact
    92101 ggttattcga tcccgttact gatccaatca tcaatgtact tccagaagaa tttttcatgc
    92161 atagctttat cttatttttt gtattattag aattattttt tgctgttttt cttttcttag
    92221 gaaaaaatag cttgaaacaa acaaaaaaga aagaactcgt ctaaatagac gttttctttc
    92281 tttttttgtt gaattattga gtaaggcgac ttcttttttc tggttctttg tgtgctaatc
    92341 gactggcagc agcagcggcg atcgctccga cgatatcatc taagaaggta tggacatgaa
    92401 cgccatcgtg gctgtttagt tcttttaaaa taccaggttt caccttgtcg atataaccat
    92461 aattcgtaaa gccgatcgta ccgtaaacat tcacgattga caaggctagg atctcatcga
    92521 taccgtaaag gccttcgtca tcttcgataa tatgttgcaa cggactcatc aattttttct
    92581 tttctgctaa tatatctaat tggattccag tgataatggc gttatgtact tcacgctttg
    92641 ttagcacgct gttgacactt tcagtacaat ccgccaaagt caaatcagaa atatagtctt
    92701 tttgtaaaaa catgacaagt tgtgcgatat cttctacagt tacgccacgt tccttcaata
    92761 gttctcttgc cttttcttct aaagtctcag ttttgacgac catattattg ctcccccttt
    92821 attttttctt tctctatttc atgttaacgg aacatgaaaa aaatgcaaga aactgctttc
    92881 gggtttaact tgaaatgcaa agagatataa aaaatcaact aggacgaaga tttttatcgt
    92941 ataagcttgt gctgtgacca ggctgagttc gttcctttgg attaatatag tgtaaagcgt
    93001 tgttcactgc agtaggtgct tcaccgagcc cagtagcaat cagtttcact tttccttcat
    93061 aggtacagat gtcaccagct gcataaacgc ctggaataga agtagacata tctgatttta
    93121 cagtaatggc atttctggta ctatcaagtc cccaagaaga aagatgttct aaattagaag
    93181 agaatccata attgacgatc agagaatcaa tcatcaaatc aatcgtctcg tcacttttca
    93241 ctttttttaa ccggatatct gtcagttccc cattattgcc tgataatcca tcgatgagat
    93301 agggagtaag caagttgaca gatgaagatt tcaagcgtga tacactatgt tcgtgcgcac
    93361 gaaattccgg gcgacgatga atcaagtaaa cttcgcttgc aataggctct aacatcaacg
    93421 tccaatcgat agcagaatca ccacctccag caatagcgac tttttttcca gcatacttca
    93481 tcaaatcatt cacgaaataa tccaatccgt ggttttcaaa tgattcagca ttatctaaat
    93541 tcaattttct tggctggaat gaaccatttc ctaaagctaa aatgactgct ttggaataat
    93601 ggatgccttt atttgtagta atctcgataa cttcgtcttc acgagtaagc gagagaactt
    93661 cttcttttaa atggaatgta tggttaaaag tagttaattg tttttctaat tgatcgatta
    93721 attcacttgc ttttattgct ggatacccag gaatatcgta aatatatttt tcgggataca
    93781 aagttgctaa ttgaccacca agttgaggta gactgtcaat gatttttgtt ttagcttggc
    93841 gcattcctgc gtaaaaagcg gcaaacatcc ctacaggacc tgcaccgatg attgtaatgt
    93901 catagatttc cataaaaatt cctccctttt cacactatag cagaatttaa ttgagaatgc
    93961 ttctcaaaaa tgtttgaatt cgaaatcgaa acggtaagtt atagaatgta tctagtgatg
    94021 aaaaataaaa gaaaacaaat ctagtatttt tacgagaggt taggtattat gttattatta
    94081 ttatgaagta tgcaaat
//
LOCUS       DAXLPQ010000005        88652 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.005, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000005 DAXLPQ010000000
VERSION     DAXLPQ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 88652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.005"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            188..418
                     /locus_tag="ACF3UO_000448"
     CDS             188..418
                     /locus_tag="ACF3UO_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFD3656503.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            515..1816
                     /gene="murA"
                     /locus_tag="ACF3UO_000449"
     CDS             515..1816
                     /gene="murA"
                     /locus_tag="ACF3UO_000449"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD3656504.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1829..2005
                     /locus_tag="ACF3UO_000450"
     CDS             1829..2005
                     /locus_tag="ACF3UO_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD3656505.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2140..2436
                     /gene="yidD"
                     /locus_tag="ACF3UO_000451"
     CDS             2140..2436
                     /gene="yidD"
                     /locus_tag="ACF3UO_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFD3656506.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2621..3088
                     /locus_tag="ACF3UO_000452"
     CDS             2621..3088
                     /locus_tag="ACF3UO_000452"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3656507.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3173..4057
                     /locus_tag="ACF3UO_000453"
     CDS             3173..4057
                     /locus_tag="ACF3UO_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3656508.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4171..4407
                     /locus_tag="ACF3UO_000454"
     CDS             4171..4407
                     /locus_tag="ACF3UO_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFD3656509.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4495..4575
                     /locus_tag="ACF3UO_000455"
     tRNA            4495..4575
                     /locus_tag="ACF3UO_000455"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4529..4531,aa:Tyr,seq:gta)
     gene            4582..4653
                     /locus_tag="ACF3UO_000456"
     tRNA            4582..4653
                     /locus_tag="ACF3UO_000456"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4614..4616,aa:Gln,seq:ttg)
     gene            4778..4948
                     /locus_tag="ACF3UO_000457"
     CDS             4778..4948
                     /locus_tag="ACF3UO_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656510.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5168..5875
                     /locus_tag="ACF3UO_000458"
     CDS             5168..5875
                     /locus_tag="ACF3UO_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3656511.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5934..6578)
                     /locus_tag="ACF3UO_000459"
     CDS             complement(5934..6578)
                     /locus_tag="ACF3UO_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFD3656512.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6704..6991
                     /locus_tag="ACF3UO_000460"
     CDS             6704..6991
                     /locus_tag="ACF3UO_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656513.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7099..7419
                     /locus_tag="ACF3UO_000461"
     CDS             7099..7419
                     /locus_tag="ACF3UO_000461"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3656514.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7500..8814
                     /locus_tag="ACF3UO_000462"
                     /pseudo
     CDS             7500..8814
                     /locus_tag="ACF3UO_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            8811..9530
                     /locus_tag="ACF3UO_000463"
     CDS             8811..9530
                     /locus_tag="ACF3UO_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFD3656515.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9658..10209
                     /gene="raiA"
                     /locus_tag="ACF3UO_000464"
     CDS             9658..10209
                     /gene="raiA"
                     /locus_tag="ACF3UO_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFD3656516.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10431..12965
                     /gene="secA"
                     /locus_tag="ACF3UO_000465"
     CDS             10431..12965
                     /gene="secA"
                     /locus_tag="ACF3UO_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFD3656517.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13091..14192
                     /gene="prfB"
                     /locus_tag="ACF3UO_000466"
     CDS             join(13091..13162,13164..14192)
                     /gene="prfB"
                     /locus_tag="ACF3UO_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFD3656518.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14297..14983
                     /gene="ftsE"
                     /locus_tag="ACF3UO_000467"
     CDS             14297..14983
                     /gene="ftsE"
                     /locus_tag="ACF3UO_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFD3656519.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14976..15860
                     /gene="ftsX"
                     /locus_tag="ACF3UO_000468"
     CDS             14976..15860
                     /gene="ftsX"
                     /locus_tag="ACF3UO_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFD3656520.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            16012..17460
                     /gene="cls"
                     /locus_tag="ACF3UO_000469"
     CDS             16012..17460
                     /gene="cls"
                     /locus_tag="ACF3UO_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFD3656521.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17797..18654
                     /locus_tag="ACF3UO_000470"
     CDS             17797..18654
                     /locus_tag="ACF3UO_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFD3656522.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18769..19689
                     /gene="pstC"
                     /locus_tag="ACF3UO_000471"
     CDS             18769..19689
                     /gene="pstC"
                     /locus_tag="ACF3UO_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFD3656523.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19689..20573
                     /gene="pstA"
                     /locus_tag="ACF3UO_000472"
     CDS             19689..20573
                     /gene="pstA"
                     /locus_tag="ACF3UO_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFD3656524.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20588..21394
                     /gene="pstB"
                     /locus_tag="ACF3UO_000473"
     CDS             20588..21394
                     /gene="pstB"
                     /locus_tag="ACF3UO_000473"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD3656525.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21410..22168
                     /gene="pstB"
                     /locus_tag="ACF3UO_000474"
     CDS             21410..22168
                     /gene="pstB"
                     /locus_tag="ACF3UO_000474"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD3656526.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22181..22858
                     /gene="phoU"
                     /locus_tag="ACF3UO_000475"
     CDS             22181..22858
                     /gene="phoU"
                     /locus_tag="ACF3UO_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFD3656527.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23435..24127
                     /locus_tag="ACF3UO_000476"
     CDS             23435..24127
                     /locus_tag="ACF3UO_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFD3656528.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            24124..24891
                     /locus_tag="ACF3UO_000477"
     CDS             24124..24891
                     /locus_tag="ACF3UO_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFD3656529.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24991..26559
                     /gene="liaX"
                     /locus_tag="ACF3UO_000478"
     CDS             24991..26559
                     /gene="liaX"
                     /locus_tag="ACF3UO_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFD3656530.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26856..27176
                     /locus_tag="ACF3UO_000479"
     CDS             26856..27176
                     /locus_tag="ACF3UO_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFD3656531.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27176..27526
                     /locus_tag="ACF3UO_000480"
     CDS             27176..27526
                     /locus_tag="ACF3UO_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFD3656532.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27693..28631
                     /gene="hprK"
                     /locus_tag="ACF3UO_000481"
     CDS             27693..28631
                     /gene="hprK"
                     /locus_tag="ACF3UO_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFD3656533.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28646..29476
                     /gene="lgt"
                     /locus_tag="ACF3UO_000482"
     CDS             28646..29476
                     /gene="lgt"
                     /locus_tag="ACF3UO_000482"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFD3656534.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29520..30545
                     /locus_tag="ACF3UO_000483"
     CDS             29520..30545
                     /locus_tag="ACF3UO_000483"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD3656535.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30560..31498
                     /gene="galU"
                     /locus_tag="ACF3UO_000484"
     CDS             30560..31498
                     /gene="galU"
                     /locus_tag="ACF3UO_000484"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFD3656536.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31623..32063
                     /locus_tag="ACF3UO_000485"
     CDS             31623..32063
                     /locus_tag="ACF3UO_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFD3656537.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32066..32668
                     /locus_tag="ACF3UO_000486"
     CDS             32066..32668
                     /locus_tag="ACF3UO_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFD3656538.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32727..33833)
                     /locus_tag="ACF3UO_000487"
     CDS             complement(32727..33833)
                     /locus_tag="ACF3UO_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HFD3656539.1"
                     /translation="MNNVKINELRQWMAQHQVELSYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            34043..35044
                     /gene="ccpA"
                     /locus_tag="ACF3UO_000488"
     CDS             34043..35044
                     /gene="ccpA"
                     /locus_tag="ACF3UO_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFD3656540.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35381..37726)
                     /locus_tag="ACF3UO_000489"
     CDS             complement(35381..37726)
                     /locus_tag="ACF3UO_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFD3656541.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            38005..38907
                     /locus_tag="ACF3UO_000490"
     CDS             38005..38907
                     /locus_tag="ACF3UO_000490"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFD3656542.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            39120..40895
                     /locus_tag="ACF3UO_000491"
     CDS             39120..40895
                     /locus_tag="ACF3UO_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFD3656543.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40961..42547)
                     /locus_tag="ACF3UO_000492"
     CDS             complement(40961..42547)
                     /locus_tag="ACF3UO_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFD3656544.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            42798..43022
                     /locus_tag="ACF3UO_000493"
     CDS             42798..43022
                     /locus_tag="ACF3UO_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFD3656545.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            43164..44915
                     /locus_tag="ACF3UO_000494"
     CDS             43164..44915
                     /locus_tag="ACF3UO_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFD3656546.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLMLDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44915..46699
                     /locus_tag="ACF3UO_000495"
     CDS             44915..46699
                     /locus_tag="ACF3UO_000495"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656547.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIITRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTSDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMMKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPIEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVEHGNHETLLAQNGLYADMYKLQSSGI"
     gene            47025..47876
                     /gene="licT"
                     /locus_tag="ACF3UO_000496"
     CDS             47025..47876
                     /gene="licT"
                     /locus_tag="ACF3UO_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFD3656548.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEDLQVHLNDSVYIALTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDKAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRCYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47971..49857
                     /locus_tag="ACF3UO_000497"
     CDS             47971..49857
                     /locus_tag="ACF3UO_000497"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3656549.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVRVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTVARKFKVNEFVGMLLGAALMNPNLSLEVLSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVNYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAMPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKDEAGETDDIQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(49897..50799)
                     /locus_tag="ACF3UO_000498"
     CDS             complement(49897..50799)
                     /locus_tag="ACF3UO_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3656550.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            51030..52433
                     /locus_tag="ACF3UO_000499"
     CDS             51030..52433
                     /locus_tag="ACF3UO_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFD3656551.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLDIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETITSIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETIGRLKEEGIEVQ
                     DELARELSSNTHIMEEV"
     gene            52433..53866
                     /locus_tag="ACF3UO_000500"
     CDS             52433..53866
                     /locus_tag="ACF3UO_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFD3656552.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWDSRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            54011..54937
                     /gene="trxB"
                     /locus_tag="ACF3UO_000501"
     CDS             54011..54937
                     /gene="trxB"
                     /locus_tag="ACF3UO_000501"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFD3656553.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            55152..56879
                     /locus_tag="ACF3UO_000502"
     CDS             55152..56879
                     /locus_tag="ACF3UO_000502"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFD3656554.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EENHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAKKVASYE
                     AIIKKMTEE"
     gene            56894..57244
                     /locus_tag="ACF3UO_000503"
     CDS             56894..57244
                     /locus_tag="ACF3UO_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFD3656555.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(57336..58196)
                     /locus_tag="ACF3UO_000504"
     CDS             complement(57336..58196)
                     /locus_tag="ACF3UO_000504"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFD3656556.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            58288..58716
                     /locus_tag="ACF3UO_000505"
     CDS             58288..58716
                     /locus_tag="ACF3UO_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3656557.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            58878..59054
                     /gene="rpsU"
                     /locus_tag="ACF3UO_000506"
     CDS             58878..59054
                     /gene="rpsU"
                     /locus_tag="ACF3UO_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFD3656558.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            59081..59527
                     /locus_tag="ACF3UO_000507"
     CDS             59081..59527
                     /locus_tag="ACF3UO_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFD3656559.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(59681..61060)
                     /gene="brnQ"
                     /locus_tag="ACF3UO_000508"
     CDS             complement(59681..61060)
                     /gene="brnQ"
                     /locus_tag="ACF3UO_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFD3656560.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            61766..62737
                     /locus_tag="ACF3UO_000509"
     CDS             61766..62737
                     /locus_tag="ACF3UO_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFD3656561.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            62761..64953
                     /locus_tag="ACF3UO_000510"
     CDS             62761..64953
                     /locus_tag="ACF3UO_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFD3656562.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKVNDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            64970..65446
                     /gene="ybeY"
                     /locus_tag="ACF3UO_000511"
     CDS             64970..65446
                     /gene="ybeY"
                     /locus_tag="ACF3UO_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFD3656563.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            65430..65825
                     /locus_tag="ACF3UO_000512"
     CDS             65430..65825
                     /locus_tag="ACF3UO_000512"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3656564.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            65840..66739
                     /gene="era"
                     /locus_tag="ACF3UO_000513"
     CDS             65840..66739
                     /gene="era"
                     /locus_tag="ACF3UO_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFD3656565.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            66882..67694
                     /gene="recO"
                     /locus_tag="ACF3UO_000514"
     CDS             66882..67694
                     /gene="recO"
                     /locus_tag="ACF3UO_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFD3656566.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            68078..68995
                     /gene="glyQ"
                     /locus_tag="ACF3UO_000515"
     CDS             68078..68995
                     /gene="glyQ"
                     /locus_tag="ACF3UO_000515"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFD3656567.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            68997..71072
                     /gene="glyS"
                     /locus_tag="ACF3UO_000516"
     CDS             68997..71072
                     /gene="glyS"
                     /locus_tag="ACF3UO_000516"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFD3656568.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGKASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            71463..72242
                     /locus_tag="ACF3UO_000517"
     CDS             71463..72242
                     /locus_tag="ACF3UO_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656569.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTIVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIDQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            72288..73232
                     /locus_tag="ACF3UO_000518"
     CDS             72288..73232
                     /locus_tag="ACF3UO_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3656570.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            73248..74027
                     /locus_tag="ACF3UO_000519"
     CDS             73248..74027
                     /locus_tag="ACF3UO_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFD3656571.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKEAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNGKTAPSRRSRSRV"
     gene            74039..74737
                     /locus_tag="ACF3UO_000520"
     CDS             74039..74737
                     /locus_tag="ACF3UO_000520"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFD3656572.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLSNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQIFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLSKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            74765..75529
                     /locus_tag="ACF3UO_000521"
     CDS             74765..75529
                     /locus_tag="ACF3UO_000521"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFD3656573.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFRKNPNYLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIGKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            75542..77359
                     /locus_tag="ACF3UO_000522"
     CDS             75542..77359
                     /locus_tag="ACF3UO_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFD3656574.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            77371..78336
                     /locus_tag="ACF3UO_000523"
     CDS             77371..78336
                     /locus_tag="ACF3UO_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFD3656575.1"
                     /translation="MNILILSCGRRCELVNAFKTALNNNEMEGKIIGADCSELAPALY
                     MCDEKIVLPKVSESNYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVV
                     LVSSEKVIDICENKILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIV
                     NNEKELLFFSEYIDNPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKG
                     QIIKDRELIETTKKMLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGAN
                     SPEYIIKMIDSKKNLRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            78329..79024
                     /locus_tag="ACF3UO_000524"
     CDS             78329..79024
                     /locus_tag="ACF3UO_000524"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3656576.1"
                     /translation="MIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIFPATFDEI
                     YRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLENADTLLTE
                     LRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPISYLLLLE
                     KFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFYQADKKIR
                     SLWEIKNFLGVIS"
     gene            79021..80139
                     /locus_tag="ACF3UO_000525"
     CDS             79021..80139
                     /locus_tag="ACF3UO_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFD3656577.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            80129..80749
                     /locus_tag="ACF3UO_000526"
     CDS             80129..80749
                     /locus_tag="ACF3UO_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFD3656578.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            80945..82045
                     /locus_tag="ACF3UO_000527"
     CDS             80945..82045
                     /locus_tag="ACF3UO_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3656579.1"
                     /translation="MAKYYNKKILIMANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKG
                     KNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYG
                     GLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQ
                     TLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNL
                     YSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHE
                     GMANTNLESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYE
                     QRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            82052..82447
                     /locus_tag="ACF3UO_000528"
     CDS             82052..82447
                     /locus_tag="ACF3UO_000528"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3656580.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            82444..83445
                     /locus_tag="ACF3UO_000529"
     CDS             82444..83445
                     /locus_tag="ACF3UO_000529"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3656581.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKIGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKNKIINLIYPKLIEDEHGE
                     YFSPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDIIQNLSDEYYTRAICKCKYKDNWKGISAKFALKNKWVFLIYIYNKLIKR"
     gene            83451..84497
                     /locus_tag="ACF3UO_000530"
     CDS             83451..84497
                     /locus_tag="ACF3UO_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3656582.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            84511..85590
                     /locus_tag="ACF3UO_000531"
     CDS             84511..85590
                     /locus_tag="ACF3UO_000531"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3656583.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            85609..87033
                     /gene="wzy"
                     /locus_tag="ACF3UO_000532"
     CDS             85609..87033
                     /gene="wzy"
                     /locus_tag="ACF3UO_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFD3656584.1"
                     /translation="MKEKINILMFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAIC
                     TWHWRKGDSIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSES
                     DMIMVKWYSCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIV
                     VPIVFVSKLLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKV
                     ITRFVFIIFALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIG
                     IYILNVITKARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNG
                     IYPFANTYLTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNG
                     GYIGGIVYIFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIV
                     KNFVYGVLIILLINFFLQQFNKRL"
     gene            87079..88584
                     /locus_tag="ACF3UO_000533"
     CDS             87079..88584
                     /locus_tag="ACF3UO_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFD3656585.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWARKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
BASE COUNT        29687 a        14906 c        18546 g        25513 t
ORIGIN      
        1 tttggaataa gggactgcga caagactttt gtctcagtcc ctttttttgc atatttttag
       61 catttatttc ctaaaaaatg taaggggatt cctatatttt taagtatact tgtttttcct
      121 tttatacatt ttatggtatt atcattttat tagttattat aaaacaatcg ttagaaagga
      181 cgtcattatg caagtatacg gaattgatgc ggtgcttcga atcgtgagtc atttggcgtt
      241 tatctactta gccttctggt ctttacgttc gttacgcatt gaaacttttt tcagaccaat
      301 gcataatacg caaattagaa tggcaatcgt acttttttca atttttttag ggtacactgc
      361 aagtaatttt ttcttagaag ttatcgcttt atgccgaaat cttttcgtta gcctgtaaat
      421 tttaaaaaaa ggtactattt taaaagcaag gatgttataa tagaaaagat tttgagtaag
      481 tgtatgctca ttggaatttt ttggagggaa caacatggaa gagatcatcg taagaggtgg
      541 caatcaatta aatggaacag taagaattga aggagctaaa aatgctgttt tgcctatttt
      601 agctgctagt ttgttagcag aagaaggtat tacgacatta gacaacgttc cgattctttc
      661 tgatgtcttc actatgaatc aagtgattcg tcacttaaac gtagatgtag attttgatga
      721 acaaaagaat caagtaacaa tcgacgcttc aagacaatta gaaatcgaag cgccttatga
      781 gtatgttagt caaatgcgtg cttcaatcgt tgtgatgggt ccgctacttg ccagaaatgg
      841 acatgcaaaa gtagctatgc ctggtggatg tgcgattggt aaacgaccaa tcgatttgca
      901 tttaaaagga tttcaagctt taggagcaaa aattattcaa aaaaacggct atatcgaagc
      961 aattgcggat gaattgatcg gtaacacgat ttatttagat ttccctagtg taggtgctac
     1021 tcaaaatatc atgatggctg ccgtaaaagc aaaaggaaca accatcattg aaaacgtagc
     1081 tcgcgaacca gaaatcgttg atttagcaaa cattttgaat aaaatgggcg ctcaagtcta
     1141 tggagctggt actgaaacaa tgcgtattga aggcgtggat catttacatg cagtcaacca
     1201 ctcaatcgta caagatcgta tcgaagcagg tacctttatg gttgctgctg caatgacaca
     1261 aggcaatgtg ctgattgcag atgctatctc tgaacataac cgcccattga tttctaaatt
     1321 gatcgaaatg ggtgcagaaa tcattgaaga agaaggcgga gtccgtgtca tcggaccaaa
     1381 acatatctta cctacagatg taaaaacgat gcctcatcct ggtttcccta cagatatgca
     1441 agctcaaatg acagctatcc aattagttgc agaaggtaca agtgtagtga ctgaaacagt
     1501 gtttgaaaat cgtttccaac atttagaaga gatgcgccgt atgaacgctc atgtcaaaat
     1561 cgacggaaat gtagcaatca tggatggaaa ccatgaattg caaggtgcag aagtatatgc
     1621 aacagacttg cgggcagcag cagcattagt tttagctggc ttgaaagcaa atggaatcac
     1681 acgtgtgcgt aacttgaatt atctagaccg tggatattat aatttccata tcaaactaca
     1741 gcaattaggt gcagacgttg aacgtgtaga catggatcaa acttctgctg aaaaaacagc
     1801 acaaacgatt gcttaaggaa gtggctgaat gagtaaccaa cgatatatct tattaacttt
     1861 gataaagatt ttaatggtga tcttattgct tatccttctt tttgtggccg gaacgatgat
     1921 cggatatggt gtcatcggtg gcggcaatcc atttaaagta tttcagccaa gtttgtggat
     1981 tcatattcga gacttttttc attgataaat aagaatcaca gtggttctag tcgatatgaa
     2041 gtgagccatg aagcagaaca tgataaaaga aaacagaagg gaacgttgac gttagtcgcg
     2101 atcccttttt ttagtaaaag aaaagaagga atctaattga tgaagaagat attgatttat
     2161 ttagttagag gatatcagcg ctttatttcg cctgcatttc cacctagctg ccgttattac
     2221 ccaacctgtt ccaattatat gataaaagca attcaaaccc atggcgcgct aaaagggacg
     2281 gtaatgggga ctgcacggat cttacgctgt catccttttg tcaaaggcgg tatcgattat
     2341 gtaccattga cattccgatt aacgcgaaat aagaaagata aaaaagaacc agattataaa
     2401 aaggttgtga aaaatacggg tagcactgag cgataaagaa acaatttgga aaatagcttc
     2461 ttatattttg caaaattgtg agttattgcc gaagtgttgg attttgaaca ccgtcaaaaa
     2521 aaaggttgtg aaaaatacgg ctagcactga gcgataaaga aaaagaggaa atttattgtc
     2581 aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag aactaaacaa
     2641 gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa aagttcaagt
     2701 atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa taggtgtact
     2761 gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa ccccaacgta
     2821 tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc tttcacaact
     2881 cgcttccagt caaactcaga tcatcatacg aaccggcagt actagcagtg cggcgttaca
     2941 tctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt ttatccatca
     3001 ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga ttttagcaat
     3061 tcacttacct aaaaatagct ttaactaata aaatttcaat tcaagaaaat gctttcaaat
     3121 gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt ttatgggaat
     3181 attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg gcaaagagat
     3241 taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaag cgcaattatt
     3301 tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa tcagctctcc
     3361 tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc cttatattca
     3421 tggatttaat attttccgag atttggaaac tctgtttcaa cttccagtaa cgattgaaaa
     3481 tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgcg attatcaaga
     3541 tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga aaggacaaat
     3601 caataaaggg gcacatcttt acggtggaga atttgggttg atgttcttaa atggcgataa
     3661 gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg aacgcaaagg
     3721 tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa ctggagatgc
     3781 aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat tattcagtat
     3841 tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg caaaagaagg
     3901 gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg atctgcatga
     3961 tttcgaaccg cagattttat tatgtgaata cagaaacgat gctaatcttg taggtgcagc
     4021 agcaaactat ctcgctgtac gtcaagggga gaattaagag ctttagagaa ggtgcagctt
     4081 gcataaaaga agtgaatgaa atgaatagga gatttttacc taaggaatgt tttatttgct
     4141 gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa agatattgaa
     4201 gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt cactcagtta
     4261 tttataggga aaaaaatgat tggtgagatc ttagcctatg gaccaaaaga atatgaaatt
     4321 ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat agaaacagtg
     4381 attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa taaagggttg
     4441 caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc tttcggagga
     4501 gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc agtggttcga
     4561 atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg actttgactc
     4621 cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag ctctcgttag
     4681 ttcgagagct cttttttttg ctttgctacc ttgttccttg aagattctgc tgatttaaga
     4741 tagagttaag ttaactacaa gaattggagg gatccacatg aaatggaaag aaaaagtaga
     4801 cgaagcagct gaaaagttat atgatttggt caaatcagaa aaatacaata ttgaagtgaa
     4861 tattccgaaa aaaggcggaa aagcggtccg ggtaaaatca aaacgcccaa cgaatcatac
     4921 aaaaaaatgg atggctaaaa accgctaata ataacaaaag atccataagt cggcattttc
     4981 atcgatttta gggtcttttg ttattttcta ggttggacat atctaaaaaa ttgtttctga
     5041 caataggagt aggaagaacg atgtgtgtct aaatcctctg ttgatggata gaaaccttta
     5101 tctttttcag ttgtgaatca ggtatatacc agttataata gaagaaacga aaggacgggt
     5161 gtacgttatg tcgaatcaat tacctgtata tatacagatt catgaccaat taaaaaatga
     5221 aatcgaacaa ggtatatgga aagtcggaga ccgtcttcct tcagaaagag aattagcagt
     5281 gaaattcaat gtcagccgta tgacgttgag acaagcaatt caaaacttgg cagatgaagg
     5341 aatcttagaa agaaagatcg gttcgggtac atatgttgca cgagaaaaag tacaagaaaa
     5401 aatgtctggt gcaacaagtt ttacagaaat tatggaatca caaaatcgag taccgtctag
     5461 tcggacaatc tcttatttct tgacttcgcc aagctcaagt gaaatggaaa aactaaactt
     5521 gagtaaagat gacacgatct tgcgaatgga acgtattcgt ttcgcagatg atgtccctat
     5581 ttgttttgaa gttgccagtg tgccacaaaa gctgatcgat ggctacagca aagcagagat
     5641 tactgaatcg ttgtatcgca cgctagaaga aaaaggcggg aaaaagatcg gtccagcgaa
     5701 tcaaacgatt actgctgtgt tggcttctga gaaaattgct gactatttag aggtaaaacg
     5761 aggagatgca gttcttcgtt tgcgccagat ttcttatttt gaagacggta cgccgtttga
     5821 gtatgtgcgt acgcaatacg taggaaatcg ttttgagttt tatttggaaa aataaaaaac
     5881 aggtgatccc tgattccgta ttagaaataa aagagaatca gaatcacctg tttttatata
     5941 tgatcagtta ccagttgctc gtgataagaa acaggaccct cttcaaattg gacttgtccg
     6001 ttcagcagct caatgatgga ttctttaaag tggtcagcac ttttttcatc tacagcacag
     6061 atgacgctaa cttgatcagt atattggatt tcttttataa aaaaatgttg gagttcaaga
     6121 taattctgta attttcctag ttgcggatac gtgatcatca cagagatctc ctgttgcaag
     6181 gtaccttcta cgattccaat gtcagacaat gcttgagaga ccgcatgagt gtatgctcgt
     6241 attaatccgc ctgtgccgag tttcgttcct ccaaaatatc gagtgactac tgcagctaca
     6301 ttgatcagtt gatttttttt gaggacttcc aacatcggta tgcccgccgt tccacttggt
     6361 tctccatcat cgctgcttcg ctggatttca tttttttctc caatgatgaa ggcgctgcag
     6421 ttatggttcg ctttccaatg ttcttttttt atttcttgaa tgaaactttt tgcttcgtcc
     6481 tctgattcta ttcgtctaag agaacagata aagcgtgatt ttttgatctc gatctcactt
     6541 tgtccatttt cttttattgt acgatagcgc tcgatcatct tgtcacctct tttttcattt
     6601 tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt tgcgcaattg
     6661 ctgtagtatg cgataataaa gacaaaggca ggtggatctg gggatgcagg aacgaatgaa
     6721 aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag taacgttgac
     6781 ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa cagcaaggga
     6841 aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct atggctggat
     6901 aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg tgttcaataa
     6961 attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa cgttgacaaa
     7021 tttctttctt tttatataat agagtaacag acgcgaagaa aacgtttgcg tagtttgttt
     7081 taaaaaggag agaaaagtat ggctaaaaaa acaatcatgc ttgtatgttc ggctggtatg
     7141 agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg aatcgactct
     7201 gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa agacgtggat
     7261 gtgttgttat taggcccaca agttcgcttt atgaaagctg attttgagaa acgtctggaa
     7321 ccaaaaggca ttcctttaga tgtcatcaat atggctgatt atggtatgat gaatggcgaa
     7381 aaagtgttag atcaagcaat cacgctcata ggtgaataaa tagaacagta taactatcga
     7441 acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg gcgaataata
     7501 tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata gactgtgagg
     7561 aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgagc aactggattc
     7621 tttgtcatcg ctgtggaatg agaacgtccg tcattgatgg acagcttgca gattacggtt
     7681 atttttgtac acattgtcta tatttagggc gatgcgacac tcaacaagat ttatatttgt
     7741 ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt tttggacagg acagcttact
     7801 gaaaaacaaa cggaaatctc aaagagaata ctttgccatt cagaaaaaag acatcatctt
     7861 atttgggctg taacaggtgc agggaaaaca gagatgcttt atcctatttt agtggaaact
     7921 ttaaaagctg gaggaagagt agcgatttgt acaccgcgag tcgatgtttg taatgaattg
     7981 tttttacgct atcgttatgt ttttccagaa gaaaaaatca cgttgctcca tgggaataca
     8041 gcaacggctt atacctttac ttcttttgtt atctgtacga ttcatcagct ataccgtttt
     8101 tatcggtcct ttgatttaat agtgatcgat gagatcgatg cgtttcctta taacggggat
     8161 gcaggattag ctcatgctgt gcaaacagcg attaaaccag acggacgatt catctactta
     8221 agtgccacac ctgataaaaa gttactaaag gagatcaagc agacgtttga catccacaaa
     8281 cttgctttac gctttcatcg gcgtttgctt cctgaacccg tcttggtttt catgaataat
     8341 tggcgacaaa aatgcaagaa caagaagaag ataaaatctt tggtgcggat cattcatcaa
     8401 ttaattaaag aaaaccatat ccttttattt tgtccaagta tcacgatgat gcatcgtttg
     8461 aaagccacac ttcaagaggc tcttccgaga tatgagatca cagatgtttc ttcaagagac
     8521 aatcagcggg cggaaaaagt ccagaaaatg cgagaagcaa aatatgacat actgttaacc
     8581 acgatgatcc ttgaacgtgg agtcacattt gaaagaatat ccgttatcgt tttaggagcg
     8641 gatcatccgg tttttactaa atcttctttg gtacaaatcg caggaagagc cgatcgtaaa
     8701 gggccttata cgaacagtca agtatatttt ttctatgaag aaaaaactgc agctattcga
     8761 aaagcttgtc aggaaatcaa agaaatgaat gaagaaggga agaagatact gtgaggtgca
     8821 gttgctgcag taaagatatc gtccaaaatt taacattcag cgagattatt ggtgtttcga
     8881 aatacagatt acctcagact tgttcagttt gtcgcgcaca atttcattta ttggaaacaa
     8941 gaggctgttc tggctgtcaa aaaccaatcc atttcaatct agagagtacg aaaaagaaag
     9001 taaattctat ccccgtttac tgcagtgact gtcaagaatg gaagaagaaa tatccgacct
     9061 atgattttca gcaccgtgcc ttttttgtgt acgatgaaaa tatgaaggcc tggctcaatc
     9121 aatacaagtt tatgggagat atccgactag caggcacctt tgcatataaa tggacgcaga
     9181 taaaaaaaga atacccgaca tacatctatt gtccaatacc tttatctgaa aaaaggcgaa
     9241 cagaaagagg attcaatcaa gtaagcgaga tgttgaaagc agcaagaatt ccttttcaga
     9301 tgctactcaa aagagagaag catctgctgg ctcaagcaaa aaacacgcga aaggaaagat
     9361 tggagatgcc tcaacctttt gaacttgcag tcaccttttc taagatacaa aataaaaaaa
     9421 tattgattat tgatgatgtc tatacaacag gacagactct tttccacgca gcagattgtt
     9481 tgcagatcgc acagccgaaa atcatccgaa ctatttcttt ggcgagatga attagatgtg
     9541 gaaatttgat agcgatttaa tttgcaaata acctagagtt cgatataata gaattaagaa
     9601 gagggaaaga gtggtccttc tccttcttga ttgtggtaga cgaaaggggt aatttttatg
     9661 tttagatata atgtacgcgg cgaaaatatc gaagtaactg aagcgattcg cgactacgtt
     9721 gagaaaaaag taggcaaact agaacgctat ttcagtgacg cacccgatgc aacggcgcat
     9781 gtgaacttaa aagtttatac agaaaaaaca gcaaaagtgg aagtaacgat cccattacct
     9841 tatcttgtat tacgtgccga agaaacttct ccagatttat acgcaagtat cgatttggtt
     9901 gttgacaaat tggaacgcca aatccgcaaa ttcaaaacaa aaattaatcg taaatcccgt
     9961 gaaacgggca tgaatactgc aaatgctgct gctttattca atgaagagga cgaaaacgaa
    10021 aatgattctg aattagatat cgtacgtacg aaacgccttt cattgaaacc aatggatagt
    10081 gaagaagcag tcttgcaaat gaacatgctg ggacataact tctttatttt tgaagatgca
    10141 gaaacaaatg gtacaagtat cgtttaccgc cgtaaagatg gaaaatacgg actgattgaa
    10201 acagactgat cagccttact taaataacaa cgaaaacttg cagcagctac tgacagctgc
    10261 cgcaagtttt tttgagtttc ctcctctttt agatgaaata tgaataaatt atgaagttct
    10321 tactttaata cgcttaagat atttcaatta tctataacta atgataaaat gaaaagtaaa
    10381 gtctacatag tctggataat acacagaagg aaaaggagat tacacaacgc atggccaatt
    10441 tgattcgttc acttatcgaa aacgataaga aagaactaaa acgtttagat agcattgcaa
    10501 aaaaagttga agcatacgct gaccaaatgg cagcattaac tgatgaacaa ttacaggcaa
    10561 aaactgctga attcaagggc agataccaaa aaggagaaac attagatcaa ttacttccgg
    10621 aagcttttgc agtcgtccga gaagcagcaa aacgtgtatt aggtttatat ccataccacg
    10681 tacaattgat gggtggaatc gtgcttcacg atggaaatat ccctgaaatg cgtactggtg
    10741 aaggtaaaac cttgaccgca acgatgccag tatatctaaa tgctctgact ggcgaagggg
    10801 tacacgtagt taccgtcaat gaatatttag caacccgtga ctcgacggaa atgggcgaac
    10861 tttataattt cttaggatta acagtggggt tgaatatcaa ctcaaaatct tcggatgaaa
    10921 aacgcgaggc ttataattgt gatatcactt atagtacgaa taatgaatta ggatttgact
    10981 acttgagaga caatatggtc gtttaccgcc atcaaatggt acaacgtccg ctgaattatg
    11041 ccattgtcga tgaagttgac tcaatcttga ttgatgaagc gagaacgccg ctgatcattt
    11101 cagggcaagc agaaaaatcc acagctttat atacaagagc agacaacttc gtgaaacgtt
    11161 tgaaagaaga agaagattat aaaatcgatg tacaatcaaa aacaatcagt ttaaccgaag
    11221 cagggatcga aaaagcagaa gaaacattcg gtttggataa cttatacgac attgaaaata
    11281 ctgcattgac ccatcacttg gatcaagcat tgagagccaa ctatatcatg cttttagata
    11341 tcgattatgt tgtccaagac ggaaaagtac tgattgttga ccagttcact ggtcggatca
    11401 tggatggacg ccgttattca gatggacttc accaagcaat cgaagctaaa gaaggcgtag
    11461 agatcgaaga cgaaacgaaa accatggcga cgatcacttt ccagaactat ttccgtatgt
    11521 acaagaaact tgcgggaatg actggtacag ctaaaacaga agaagaagaa ttcagagaaa
    11581 tttataacat ccaagtatac cagattccga caaatcgtcc ggttatccgt gatgatcgtc
    11641 cagatttgct ttacccaaca ttacaaagca agttccacgc tgtcgtgcaa gatatcaaag
    11701 atcgctaccg caaaggtcaa cctgtgttag tcggaactgt tgcggttgaa acatctgagt
    11761 tattatcaga tatgctgaat caagaacgta ttcctcatga agtgctgaat gcgaaaaatc
    11821 actttaaaga agcagagatc atcatgaatg ctggtcaaaa aggtgctgtg acgattgcta
    11881 ccaacatggc tggtcgggga acagatatca agttaggact tggggtaaga gaacttggtg
    11941 gtctagcagt tatcgggaca gaacgacatg aatctcgtcg tatcgataac cagcttcgag
    12001 gacgtgcagg acgtcaagga gaccctggta tgtcacagtt ctacttgtca ttggaagatg
    12061 atttgatgaa acgattcggt tcagaacgaa tcaaatcttt cttagatcgg atgaagatcg
    12121 gtgaggaaga tgctgttatc caaagcaaga tgctgacgaa acaagtagaa tctgcacaaa
    12181 aacgtgtaga aggaaataac tatgacacac gtaaaaacgt cttacaatac gatgatgtga
    12241 tgcgtgaaca acgtgaagta atctataaac agcgacaaga agtaatcatg gaagaaaaaa
    12301 gcttatccaa gccactaatg aacatggtca aacggacaat cagtcgtgta gtagatgcgc
    12361 atacacaatt agagaaagaa aattggaatt tggaaagtat catcgatttt gccggcagta
    12421 ctcttgtcca tgaagatagt attactcttg cagatatcga aggaaaaaca gctcaggaga
    12481 tcaaagagta tctaaacgaa cgagcacaag aagtatttaa taccaaagcg gctcaactaa
    12541 atggtccaga gcaactgttg gaatttgaaa aagtcgtgat cttgcgtgtt gtggactcta
    12601 aatggacaga ccatattgat gcaatggatc aattacgtca gtcaatcggc ttacgtgctt
    12661 atggacagaa caatccatta gtcgaatatc aaacagaagg ctataagatg tttgaagata
    12721 tggtaggcgc catcgagtat gaagtcactc gaatctttat gaaagctgag atccgtcaaa
    12781 acgtacagcg tgaacaggtt tctcaaggaa cagcttctca ctcagaagac ggagatgcca
    12841 aagaaaatag taatactagc gcgaaaaaac agccaatcca tgtgaacaag gtcggaagaa
    12901 atgatccttg tccttgtgga agcgggaaaa aatataagaa ctgtcatgga aaaaatgcaa
    12961 actaatttct gacagcagga ttggtgagac aaattctttt tttaagaatt cgtctcacct
    13021 tctttctgtt atttgctgat tctgttagac tagatataat gaaaaaagta tagtgaaaga
    13081 aggaaaaaac atggaaatat ccgaaattcg aaatctcctg acagaaatgc aggaaaaggt
    13141 cacaagcttc aggaggtctc tttgacttag accagctgga agaagacatt gcggaagcag
    13201 aagcaaaaat ggctgaacct ggtttttggg atgatagcga agctgctcaa aaagtgatca
    13261 gtgaaaacaa tgcaaataaa gaaacttatg atcaattcca ttctcttgct gaagaactgg
    13321 aagaaatcga attgatggtg gagatgttgc aggaagaacc tgatgcagcc atgcaagaag
    13381 aagcagaaac acgtatcaat gcgctagatg aaaaaatgaa gacatatgaa ttatctatgt
    13441 tgttagatgg tccttatgat cgaaacaacg ccatcgttga attgcatcca ggggctggcg
    13501 gaacggagtc ccaagattgg ggcagtatgc ttttacgtat gtatacacgc tgggcagagc
    13561 agcatgggta tcaagtagag acactagatt atcaagcagg tgatgaagca ggaatcaaga
    13621 gtgtgaccct actgatcaaa ggacacaacg catttggtta tctgaaatca gaaaaaggtg
    13681 ttcatcgcct tgtacgtatc tcgccttttg actcagcgaa acgacgtcat acttcttttt
    13741 gttcggtaga tgtgatgcca gagcttgatg aaacgatcga tatagaaatc aatccagatg
    13801 atttgaaaat cgatacgtac cgagcaagtg gtgcaggtgg tcagcacatc aataaaacag
    13861 aatctgctgt acggatcact cacttgccta caggaacagt agtagctagt caggcacaac
    13921 gttcacaatt gaaaaaccgt gagcaagcga tggggatgtt aaaagctaag ctttatcaat
    13981 tagaagtgga aaagaaagaa caagaagcag ctgcacttcg aggagaacaa aaagaaatcg
    14041 gctggggttc acagatccgt tcttatgttt tccatccata ttctatggta aaagaccatc
    14101 ggacaaacgt agagacagga aatgtccaag cagttatgga cggtgacctt gatttattta
    14161 ttgacggcta tttaaaaatg catctacaat aagaacccat tgttaaattg aaataaaatt
    14221 gtaagatttt gcaagcatgt tgaaacattg ccatgctata atagctaaag actgaaaaag
    14281 atatggagag aacgccatga ttgaaatgaa ggatgtaatg aagaagtact caaatggtac
    14341 gaccgctatc cgcaatctct caattgtcat cgaacaagga gagtttgtct atgtggttgg
    14401 tccgtctgga gccggtaaat ctacattcat caaattgatg tatcgagaag aaaaagcttc
    14461 aaaaggaact ttgaacgtcg caggtcatga tctaatagca atcaaaaacc gcgaagttcc
    14521 ttatctacgc agagaaatcg gcgtggtgtt ccaagactat aaattattac caagaaaaac
    14581 agtatatgaa aatgttgcgt acgctatgca agttatcggc agaaaacctc gggatatcaa
    14641 aaaacgagta atggaagtgc tggaccttgt tggtttgaaa cacaaagttc gagtctttcc
    14701 tagcgaatta tccggtgggg aacagcaacg tgtctctatt gctcgggcaa tagtgaatac
    14761 gcctaaagta cttatcgcgg atgaaccgac aggaaatctg gatccagaaa actcatggga
    14821 aatcatgaaa ttattagatc ggatcaatgc ccaaggaact actgtcgtga tggctacaca
    14881 taacagtacg atcgtaaata cgattcggca ccgagtaatt gctatcgaaa acggccgcat
    14941 tattcgagat caagcggaag gggaatatgg atacgatgat tagaaccttt ttccgccatt
    15001 tattagaaag tatcaagagt ttgaaacgta acggctggat gacagttgct tcagtcagtg
    15061 cggtaacgat cacattgact ttagtcggtg tattcatggc agttatcatg aacgcaacta
    15121 aattagctca agatatagaa ggaaacgttg atgtctctgt attcgtagat atcggtacaa
    15181 aagacgaaga gatgaaaaag ctagaaaaag aattgaatga cttagatcat gttaaaaaag
    15241 ttgaattttc aagcaaagaa caggaattga aaaaaatcca aaacgaaatg ggtgattcct
    15301 ggaaattgtt tgaaggtgac aataacccgt tatatgatgt gtatgtagta agtgctactg
    15361 atccttctta tacaaaacaa gtagcagaag aagcagcaga tttgaagaat gtttctcgtt
    15421 ctgattacgg tggagcttcc tcagatcgga ttttccaaat cgctggtgca gttcggacat
    15481 ggggattagt tgcagcggca ttgctgctgt tcgtagcgat gtttctcatt tcgaacacga
    15541 ttcggatcac gattttgtct agacagcgtg aaattcaaat catgcgttta gtcggtgcaa
    15601 aaaatggata tattcgctgg ccgtttttcc ttgaaggtgg ctggatcggt ctgatcggtg
    15661 cgattcttcc gattttgatc atcacatttg gttatgcatg gtttttccaa ttgatcaatc
    15721 catcattatt acgttcccat tattcattga ttcatccaca aaatatcgtt tggaaaatca
    15781 atcttttaat ggtcggcatt ggtgtgatca ttggttcact tggctcgatc atttctatga
    15841 gacgtttctt gaaattctaa taccacaata taaataaaat gagaaagttg gacagtttcg
    15901 ttccagcttt ctttttttat tggctaggag aatagaagga agcggctttt ttccctttac
    15961 tttaaaaaac aacttgggta ttcttaagtt ggtagaagaa gaggtgaagc cgtgaaaatt
    16021 atcgttgaca atttttttac gatccttttg attatgaata ttttgctttc ctttatcatc
    16081 gtttttcgag aaagaaagga aactgctcaa acatgggcat gggtgctcgt tttgatgttc
    16141 attccagttg taggatttat tttatatatt tttttaggaa gagggatttc caaagagaaa
    16201 atctttgatt tgaagatcca agggaaaatc ggtaagaacc tggaaattga agaagacaaa
    16261 caggcattga tgcgagggct ttatcctcat ccgcctactg gacaagtaga tgtgaaacaa
    16321 ttgatctata tgctcacggt atttgaaagt acgctctata cgactaaaaa tgaaatcact
    16381 ttatttacag atggtcgtga aaaattcgat gcgctgattg aagatatcaa gcaggcagaa
    16441 gaccatatcc acttccagta ttatatttat cgcagtgatg cattaggtga agaagttcga
    16501 gatgcattga cagaggcggc aagacgaggg gtaaaagtca gagtccttct tgatgcatgg
    16561 ggttccacac aagtttcttc cagctttttt cagaatttga aaaaagcagg cggagaagtc
    16621 gcatttttct ttcctctatt tgttccgtat attaatcctc ggatcaatta tcgcaatcat
    16681 cgtaaaatcg tagttattga tgggaaaatc ggatatacag gtgggttcaa tgttggaaat
    16741 gaatatctag gattggtaaa gaaatttggt tattggcgag acaatcattt gcgtatttac
    16801 ggagaagcgg tgtatacctt gcaaaaccgt tttttgatgg actggaattc tcagcataca
    16861 aaagaagtag gctattctcc caaatttttt ccgtccattc actctactgg tgatatagct
    16921 gttcaaatcg tgacaagcgg accagatacc gaacatgaac aaatcaaaat gacttatttg
    16981 aaaatgattt cgttagccaa acgggagata ttgatccaaa cgccttatta cataccggat
    17041 ggatcgattc atgaagcact gaagttggct cttctttcag gcgtaaaagt tcatatccaa
    17101 atacctaaca aaccagatca tcttctcgtt tactgggcaa cgtattcttt cgctgcagag
    17161 ctaatcgagt atggagcaag gatcgaaaca tatgagaatg gatttattca tgcaaagacg
    17221 atgattatcg atggtggcat tgtttcagtt ggctcagcaa atatcgatgt tcgttcattt
    17281 cgcttggact ttgaggtcaa tacactggtt tatgatgaac gaatggcttc acgtgtaaga
    17341 aaagcttttt ttgaagactc gaaaatttct acgcatctca caaaagaaat gtatgaaaac
    17401 cgaggaataa tcatcaagat gaaagaagga ttagcaagat tgatttcgcc gctcctttaa
    17461 aacataaaaa ggacatgaga accatcaaca gatggagatc tcgtgtcctt ttctaacggg
    17521 gccatttctg agagtacgtc agaaatggag aaagcgtctc gcatgagcga aattaacttt
    17581 ggggtatctc ttgttttttg gggaaagcaa gaaataagct aatatatgct attaaaagag
    17641 acacatttca aagccagtat agcatagaaa cttttaatga gatagttttt tttacaatta
    17701 tgagaattta ttttgttatt taatgatttt gattcgtttt catcaagtaa tgaaaatgat
    17761 aaaataaaca tactttagga ttaaaggaga tttctaatga aaaaacttaa attattctta
    17821 ccaataatag gattagctat tcttttatca ggctgttcaa agtggattga tcgaggagaa
    17881 tccattacgg ctgttggctc ttctgcttta cagcctttag tagaaacagt tgctgaaact
    17941 taccagacag aaaatcctgg aaaattcatc aatgtacaag ggggcggaag cggaactggt
    18001 ttgtctcaag tacagtcagg agcagtcgac atcggaaact ctgatttgtt tgcggaagaa
    18061 aaatcgggga tcgatgcctc agcattagtc gatcatcgag tagcagttgt tgggatcact
    18121 cctattgtga acaaggatat tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta
    18181 tttacaggcg agatcaaaaa ctggagtgaa gtcggtggaa aagatcagcc agtagttata
    18241 ttgaaccgcg cttcaggaag cggaacccgt agcacgtttg aaaaatgggt attggacgga
    18301 gaaacagctg ttcaggcaca agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc
    18361 gacacacccg gtgcaatcag ctatgttgct ttttcttatg tttccgatga tgtagatacg
    18421 ttgaatgtta acggtgtaga accgacagat gaaaatgtga caacgaacaa atggacgatt
    18481 tgggcatatg agcatatgta cacaagagat catccaaaaa aactgacaaa agaattttta
    18541 gactatatct tatctgatga agtacaagat aacatcgttg gagaactagg ttatatccct
    18601 gtttctcata tgaaagtcga acgtgattgg caaggaaata tcgttaaaga gtaatcttta
    18661 cacaaaattt acaaacttag ctaaactttt acatgttatt aaaaccaaat tgatgttcaa
    18721 tttgtacact gagtgagtat gttaaacctg attaaggggg agtcatctgt ggaagatgtg
    18781 aaaaaagtat tattaacaaa atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc
    18841 agttttttat gtatcgcgct gatcgtgttg gttgtattat ctatttttta ttttgtagct
    18901 agtaaaggat tggccacctt ttttactgat aagatcaatg tatttgattt tctgtttggt
    18961 acagattgga atccaagcca aatcggagca aatgggaaac caatggtagg ggcattgcct
    19021 atgatcacag gttcgtttat tgtgaccttt ttatctgcta tcgttgccac gccatttgcc
    19081 attggtgcag cagtattcat gacggagatc tctcctaaaa acggaacgaa gatcttacag
    19141 ccggtcatcg agctgcttgt aggtattcct tctgtcgttt atggttttat cggtttatca
    19201 gttatcgtgc cttttgtcag aagtattttt ggcgggactg ggtttggtat cttagctggt
    19261 acatttgtgt tgttcgttat gatcttgccg actgtcacaa cgatgactgt tgatgcatta
    19321 aaggcagtgc cacggcacta tcgggaagct tcattagcgc ttggtgccac aagatggcaa
    19381 acaatctaca aagtcgtgct acgagcagcc gtgcccggga ttttaacagc agtcgttttt
    19441 ggtatggctc gtgcgtttgg tgaagcctta gctatccaaa tggtcatcgg taatgcagca
    19501 ttgatgccaa caggtcttac tactcctgct tctacattga cgtccatctt aacaatggga
    19561 atcggaaata caatcatggg aacagttgaa aataatgtgt tatggtcatt agcgctgatc
    19621 ttgctattga tgtcattatt ctttaatatc gtgatccgta tgattgggaa gaaaggagag
    19681 ctgaaataat gaacgcaaaa cgctcagata aaattgctac aggtgtttta tatatagttt
    19741 cggggatcat cgtattgatt ttagcagctt tactacttta tatcttagtt cggggaatac
    19801 cgcacatttc atggtccttc ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa
    19861 tcgggatcca gctatttaac tcgatttatt tgcttttgat cacgatgatc atcagttttc
    19921 ctatttcttt aggtgcgggt atctatcttt cagaatatgc tggaaaaaac tggctaacag
    19981 atgtgattcg cacgtcgatt gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat
    20041 tcggtttctt ggttttcgtt attcaattcc agtatggttt ctcgattatt tctggtgcat
    20101 tggctttgac tgtattcaac ttgcctcttt tgactagaac agttgaggag tctttacaag
    20161 cggtccatta cacacaacga gaagcaggat tggccttagg tttgtcacgc tgggaaacag
    20221 tgataaaagt ggtggttcca gaagcgacac cagggatttt gactggtgtg atcctaagtt
    20281 ctggaagaat ttttggtgaa gcagctgcat tgatctatac ggctggacaa agtgcacctg
    20341 cgttagattt tacgaactgg aatccattaa gtgtttcaag cccgatcagc attttccgtc
    20401 aagctgaaac attagctgtc catatttgga agatcaatac agaaggcacg atgcctgatg
    20461 gtgtttctgt ttcggctggc gcttctgccg tgttgattat tgctgtttta ctgttcaact
    20521 tcggcgctcg tgcgattggc aaacgattat accgaaaaat gacttcagcc taaggagaag
    20581 aagcaaaatg aaaaaatata actggaatga aacaaatgtc atcaccatgc caaaagagaa
    20641 agaagtagca ctatatacgg atgatctaca tgtctggtat ggcgacaatg aagcaatcaa
    20701 aggagtggat ctggaatttg aaaaaaataa gatcactgca ctgattggtc cttccggctg
    20761 cggaaaatct acgtatcttc gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa
    20821 aatcactggg aaaatcatgt atcaaggcgt agatattaat gcgcctcaag tggatgttta
    20881 tgagatgcgc aaacggattg gcatggtttt tcaacgtcct aatccgttca gcaagtcgat
    20941 ttatgacaat attacatttg ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga
    21001 tgaaatcgtt gaaacaagct tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt
    21061 ggacaaaagt gccttggctt tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc
    21121 gatcgcgatg aaacctgata tcttgctgct agacgagccg gcaagtgctt tggaccctat
    21181 ttcgacagga acggttgaag aaacacttgt aaacttgaaa gaagactata cgatcatcat
    21241 cgtgacgcat aacatgcaac aagcagctcg tatcagcgac tatactgcct ttttctattt
    21301 aggaaaagta atggaatatg acaaaactaa caagatattt accagaccaa aaattcaggc
    21361 aaccgaagat tatgtgtccg gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga
    21421 gattatttca tctaaagatc ttcatctgta ttatggaaag aaagaagcac taaaagggat
    21481 cgatctaagc ttcaatcaag gggaaatcac tgcgatgatc ggtccttctg gttgcggaaa
    21541 atccacttat ctgcgttctt tgaaccggat gaatgacctg attccgaatg taacgatcac
    21601 cggaagtgtt ttatataaag acaaagacat ctatggtcca aaaacagatg ttgttgaact
    21661 aagaaaagaa atcggcatgg tattccagca gccaaaccca tttccttttt ctatctatga
    21721 aaatgtcatc tatggattga aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt
    21781 agttgaagaa agcctgaagg cagcgtctgt ttgggatgat gtgaaagaca aattgcataa
    21841 aagtgcttta tctttatccg gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc
    21901 agttaatccg gaaatcatct tattggatga accaacaagt gcgcttgatc ctgtttctac
    21961 tgggaaaatc gaaagtatgc tgttagaatt aagagagcgg tatacgatga tcatcgtgac
    22021 ccataatatg tctcaagctt cacgtatttc agataagacg gcattctttt tagatggtca
    22081 cttgatcgaa tacaatgata cgaagaagat attcatgaat ccagaaaaac aagagacaga
    22141 agattatatt tcaggtcgat ttggataagg aggaaacgga atgctacgta cacaatttga
    22201 agaagaattg ctgaatctcc ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc
    22261 cgtgcacaag tcagttcgtg catacatcaa acacgataaa atcttagccc aagaagttat
    22321 cgaaaacgat ataaatatca ataacatgga aacacgcttg gagaagaaaa gttttgaaat
    22381 gatcgcattg caacagccag ttacaactga tttgcgtatg atcattacgg tcatgaaagc
    22441 tagctcggat ttagaacgta tggccgatca tgcggtgtct gttgctaaat ccacgattcg
    22501 cgtaaaaggg cagacgagaa taccggaaat cgaaaaagag atctccgata tgtccgatta
    22561 tgtgaaaaaa atggtggaca acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc
    22621 acgtacgatc gccaatatgg atcaaagagt caatgactat ttcaatcgaa tctataatgc
    22681 aacaatcaaa aatatgcagg aaaatcctga gacagtcatc agtggaacag actacttgaa
    22741 tgttgccagt tatctagaac ggatcggaga ctatgtgaca aacatctgtg aatggatcgt
    22801 ctacttggct acagggaaaa tcactgagtt aaatacgaac cacaatgaga ttttctaaac
    22861 tgaagctgtg attatgccgt ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa
    22921 aagctgttct gcatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc
    22981 gtttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg
    23041 tttgtgacaa aacatgtcac aaaccctttt catcatttca tagaaaggat aaagaatgca
    23101 aaaaaaaatt agcatcatca ctatattttt tatttgtgtg cttacttcat gggttattca
    23161 gcatcaagcc gctttatatg aagtacctgt catcgagata gaaaaagtac gaataaaaga
    23221 ggatcatcaa ttgattacag gaaaactgat gaacacggat caaaaaggag aatcgattta
    23281 tttatcggtt ccttatcaaa aaaatcaaat agaaacagca aatataaaag cgagacaaat
    23341 gtatctagtc caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa atgatggctg
    23401 gcttttcttc ttcacaagta tcttcattgg cgccatgttg cttattggtg gaaaacaggg
    23461 tctatttgct ttaggaagtc tcatcatcaa tatcgtttta cttttacttt tgttgctcat
    23521 ctttactaaa acagaaggga tttctctatt aaatatatct atcctgttcg tcgttatagg
    23581 gatgattatt agcatattgg ctttagatgg atggaataga agcagtataa tcaaaatttc
    23641 agctgcagtt acgagtgttt ttttagcatt ttttatttgt cttttgacaa tgaatcattg
    23701 gaaagaccaa ggactgcgct atgaggaact gaattatctg acacgaccgt atcgttctgt
    23761 ttttctttct agcgtactga ttggaacagc tggaggaaca ctcgataccg ttatcacagt
    23821 cattgcgaca ttagaagaat tgactaagcg acaaccagaa ataacagcga aacagttatg
    23881 gctttcagga aggcaagtgg gtcgagatgt gattggctcg atgaccaata tccttttgtt
    23941 cgtctatatc agtgggtcag ttccatcgct tcttttatat ttaggaaatc aatggtcgtt
    24001 caaagaaacg atagaacagc atttatcatt ggaattttta cgcgtcattg ctggcagctt
    24061 aggaatagta ttatcgatcc ctatctcggt cctctttttt ctgactgtaa ggaggctgaa
    24121 acgatgaatg tacttattat acttgttggg attttagcaa tcagcgtgct acttattggc
    24181 ggtacgcaag gtatgtatat tcttttaggc ttattcatca atttagggat ctttttcctg
    24241 ttgttattcg gttatcatca gaagtggccg atactggcat tgtcggtcat aggattttta
    24301 ttgattgctg tggttatctt attttttatc aacggttata atctaaaaat gcgtgcagct
    24361 tttgtgagta tactgatctt tttattttgt ttcctactat tgcttcctat cactgatttt
    24421 ttagcaatcc aaggttttac atcggtagaa ctagaagaat tatctggctt agataagact
    24481 ttagcgattg attttagatt acttacgaga tcgttgcttc tgattagtct tagtggtgct
    24541 gttttagatg cgagtgtagc aatttctagt gggacattcg aagtatatca ggcaaatccg
    24601 caattatctt tttaccaatt gcgccattct agtttcgcta ttgctaaaaa aatattggcg
    24661 tcaacagtaa tgacacttct ttttgcattc atgggaagtt ctttagcgtt gatcctctgg
    24721 tttattgatt tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt tgttctagaa
    24781 tatacgatgg ctattcttac cacattgtcc gcactacttg ttcttccttt aacctgcgtg
    24841 actacagcat atctctttac aaaaaagaaa gaacaactca agatggagta aaagttacaa
    24901 cttaagtcct atgacatttt tactgaatca gtgcataata tggatgtaag gaaaagcttg
    24961 caaacaattt tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat tttagattta
    25021 gtgaaaaaag gaatcctttc gactgaagaa ggcttagatt tattagaaag catggcaact
    25081 gaaaaagacg aaaagcaaat caaaaaagaa gcagacaagg taactgctag tcataaagaa
    25141 aaagatcagg caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga aatttctgag
    25201 ccagttgatc caaaggaaag agaaagacaa gatcaagaaa acttagaaaa gatcttagat
    25261 gaactagcaa ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa tgctcaattc
    25321 gctgacaata aggcagcacg caatgagaaa caggaagcat tgatgcagct gaatacaaaa
    25381 gaagaattag gcgagttgac agaagaagaa ttagcacagc gtcagacgtt agaagcagaa
    25441 atcaaagaat tagaagctag tggcgataca ctgttagaag aacaattgaa attagaagca
    25501 gaattaaaag atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt tactgataag
    25561 tttgaattgc cagatgattg gaaagatcaa gcaacagata cactgaatca agtaggcgaa
    25621 aaaatgtcag aagctggatc acagttaggc aaattcttga agaaaacatt ccaaactgtt
    25681 tcagaaacag tgaatgacaa catggaatgg aaagatgtca gcttacgtgt ccctgggatt
    25741 gcgacaacga aatttgagca tgaattttac tatgaagctc ctgcagcaag tatccttgat
    25801 atcaaggcag caaacggaaa cgtgacgtta aaaacgtggg acagcaacga tgtgaaagtt
    25861 gaagctaaga tcaaacttta cggaaaaatg ggtgctgaac catttgaagc attctctgaa
    25921 cggagccaga ttgaggttaa tgaagatcat atctccttcc aaattccaaa taaacgtgtg
    25981 cgtgcagacc ttgttttcta cttacctaaa cgagtatacg accacgcagc tattaaactt
    26041 ctaaatggca acatcatgat tgaaacattg gaagctaaag atatttatac aaaatctacg
    26101 aatggtaaca tcatcgtgga ccaattaact gcaacgatgc tggaagtaga aggtgtaaac
    26161 ggcaatatcg atattcgaaa cgggaacatc ttagattcta ttatcgaaac agtaaatggt
    26221 acagtgacat ttggtgcgac agcagaaaac ctttctgtgt ctttggtaaa tggtgatgta
    26281 cgtcttacga ttaaagaaga taatttgaaa aaagtagaag caagttcagt gaacggaaat
    26341 gtcaaagtcg ctttaccaga tggcatcggt ttggaaggac atgctaaaac aagtcttgga
    26401 agtatcaaca gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga acggacaaac
    26461 caaatgttgc aattccgtcg tgtttcagat ggtgaaatcg cgcaagtgca actttcaacg
    26521 acaacaggaa gtatctattt aaaagataca gataaataaa gaggttgtga aagagatgtt
    26581 cagccttgag caataagaag cgattttgta aaatagcttc ccctatttta caaaattgtg
    26641 ccttattgcc gatagtctat ctcttgaaca ccgtttacca agagattatg aacctgccaa
    26701 ttatcgccga gtcacaagga ataatttcag aaaaagctcg tcacgtttta tgaatatggt
    26761 aatttgtgac cgagaatttt gcagaaagac accgattaag aagaaggttg tcacaacgat
    26821 tttcttcatt taaaatagta gaacagaggt gagacatgat gaaaaaaaag ttgacaaaat
    26881 ctaataaaaa tgttgttttg acagggactt tagcaggaat aggagaatac atcgggattg
    26941 atccgactgt tatccgtgtg ctttatgtat tcctgagctt agttgctttt ggaagtccaa
    27001 ttattttata cattttatta gctttgatta tcccatctgc gcgttctgca cgaacaaact
    27061 atggacataa caatgcatat tatgaaaaaa acaattatcg tgaacaaact cgtgaacaaa
    27121 caaaaaaacg caaagaagcg gaaaaaatcg atgatgacga atggagtgac ttttaatgtc
    27181 gtactttcaa cgtattttag ttaatacgtt aacattcata tcattggctg ttctttttcc
    27241 tgcgatggtc catgtgagca gtatttggac ggccgttctt gccagcttcg tattgtctgt
    27301 gttgaatatg tttgtcaaac cgattttgac gatactgtcc ctgcccttta cattagtcac
    27361 attgggattg tttacgtttg ttatcaatgc agcgattctt aaaatgacct ccttttttgt
    27421 gggagcagaa cattttagtt tttcttcatt cggtgcagcg ttgttagtag ctatcttgat
    27481 gtcgcttgtc aatgtaattg tcagcgaaca taacagtaga aaataaaaga aagctgtgcc
    27541 gaactatcgg cgcagttttt ttatttagaa tcaggaatgc gttttctatt acattggtaa
    27601 ttaaataaaa acgttttttt taattggtag tacttttggc tagacaatga taaaatgata
    27661 gagaacactc taatagaaat gaggtagcat gaatgtcaga agttgtaaaa gttagccaat
    27721 tagtgaaaaa attatctttg gaaatcgtga caggcgacga gaaaagctta gaccgtgtca
    27781 tcgtaactgg ggacatctca cgcccaggac tagagttgac tggttatttt aattattatt
    27841 cccataatcg tttacagcta tttggcagta aagaaatcag ttttgcggaa cggatgatcc
    27901 cagaagagcg tttgatcatc atgagaagat tatgtagtga agatatgccc gcatttatta
    27961 tttcaagagg attaccagct ccagaagaaa tgatccaggc agcaaatgaa aatgggatag
    28021 ctgtactgcg ttctcccatc tcaacttctc gtttattagg agaattatcc agttatttag
    28081 atggtcgcct tgcccctcga acaagtgtcc acggtgtttt agtggatgtt tacggattag
    28141 gtgtactgat tcaaggtgac agtgggatag gaaaaagtga aacagcgttg gagttgatca
    28201 aacgcggcca tcgattgatc gcagacgatc gagtagatgt ttatcagcaa gatgaattaa
    28261 cggtgatcgg agaaccgcct aaaatcctgg aacatctgat tgaaatccga ggaatcggga
    28321 tcattgatgt aatgaatctt tttggtgcga gtgcggtacg tggctctatg caagtccagt
    28381 tggctgttta tctggaagca tgggcaaaag ataagaaata cgaccgtctg ggctctgaag
    28441 acacgaccgt tgaaatcgcg gaagtgggca ttccacaaat aaaaatccct gtcaaaacag
    28501 gacgaaacgt tgcaatcatc attgaagtag ccgcgatgaa tttccgtgca cgtacaatgg
    28561 gctttgacgc aacgaaaaca tttgaagaaa gattaagtcg cttgattgaa gaaaactcag
    28621 gcaacgacta gcaaggagtg acaatatgtt agcacaaatc aatcgagttg cttttgagct
    28681 tgtagggatt cctatctact ggtatgcatt gatcatcgta tcaggtatca ttatcgctat
    28741 gtggcttagc agcagagagg ctgttcgggt aggattaaaa gcagatgatg tgacagattt
    28801 tatgttgtgg ggattgccta tctccattat tggcgctcgc ttatattatg ttttatttga
    28861 tcttccccag tatatagctg atccaatcca aatattcaat atccgttcag gaggcttagc
    28921 tatttatggc ggactgattg caggcgcgat cacgctgtat ttttttacta aatatcattt
    28981 tatttctttg tggacttttt tagatatcgc tgcaccaagt gtattattag cacaggcaat
    29041 cggtcgttgg ggaaatttca tgaaccacga agcatatgga ccagacacga cgcgaagctt
    29101 cttagaaagt ctgcatttac cgcaattcat cattgataat atgtatatcg aagggatcta
    29161 tcgtcaacca acatttcttt atgaatcact ttggagtttg attggattta ttttgctttt
    29221 gtttttacga aagaaaccac accttttgaa aaaaggcgaa gtccttttat gttatctaat
    29281 gtggtatagt ttcgggcgtt tctttattga aggattacgt acagacagtc tttacttttt
    29341 aggtgtgatc cgtatttctc aattattatc tgctgtgtta tttgtcggta cattgattct
    29401 atttatttgg cgcagaaaaa aaggaaattt accggattat gaccgctcat taggaaaaaa
    29461 tcaacaaatt atctgatttt tagagcgtta aaaatgaaaa aaatttcagg agtggtaaaa
    29521 tgaattatag agtagcggtt ttaggaccag gctcttgggg tactgctttg gcacaagtcc
    29581 tcgccgaaaa cggacatgac gttcggattt ggggacatcg tgcttcacaa gtagaagaaa
    29641 tcaacaccca acacacgaat caacgttatt taccagatca ttatctaccc gattccatcc
    29701 aagcattcac caatatggaa gatgcagtaa aagacgcaga tgcggtgcta ttcgtcattc
    29761 caacgaaagc aatacgttct gttgcaaaag aactagtgcc taaattgaat acaaagccag
    29821 tgatcatcca tgcaagtaaa ggattagaac agggaacaca taaaaggatc tctgacatct
    29881 tgttagagga aatcccagca gaaaaaagaa aagctgttgt tgttctttct ggaccaagcc
    29941 atgcagaaga agtagcaaaa catgacatca ctacgatcac agctgcaagt acagatgcaa
    30001 aagcagcaaa atatgtacaa gagctgttca tgaataatta ttttcggatc tataccaatc
    30061 ctgatgtgat cggtgtagag atgggggcag ctttgaaaaa tattattgct attggtgctg
    30121 gcgctattca cggcttaggg tttggcgata atgcaaaggc agcaatcatg acgcgcggat
    30181 tagctgagat cagccgttta ggtgtagcaa tgggtgccaa cccgctgacc tttatcggat
    30241 taagcggaat aggcgatcta gtcgttactt gcacaagtgt tcattctagg aactggcgcg
    30301 caggcaactt gttaggacaa gggcagcccc tagaagaggt gctagccaat atgggaatgg
    30361 tcgttgaagg tgtgaatact acccaagcag cgatggaact agcccaaatg atggaaatcg
    30421 aaatgcccat cactcaaaca atctatgaag tgctgtatga acaaaaagaa atcaaaacag
    30481 ccgcaaaaga aatcatgtta cgtgatggaa aaaaagaaaa tgaattctca ttaacaattt
    30541 tttgaaggag cgaatgtata tgaaagttaa aaaagcagtt attccagcag caggattagg
    30601 aacaagattt ttaccagcaa caaaagctat ggcaaaggaa atgttgccaa ttgttgataa
    30661 accaacaatc cagttcatcg ttgaagaagc gttgaaatca ggtatcgaag acatcttgat
    30721 cgttacagga aaagctaaac gaccaatcga agatcacttt gattcaaata ttgaattaga
    30781 aacaaaccta agtgaaaaag gaaagaccga attattgaaa ttagtagaag aaacgacaga
    30841 tgtcaacttg catttcatcc gtcaatctca tccaaagggt ttaggacatg ccgttcttca
    30901 agcaagagcc tttattggaa atgaaccatt tgtcgttatg ctaggcgatg atataatgga
    30961 agacgaagta ccattgacac agcaattaat cgatgattac gaacgtactc atgcttctac
    31021 gatcgccgtt atgcaagttc ctcatgatga aacttcaaaa tacggaatta tcaatccagg
    31081 agaagtattg gaagatgggt tatacaatgt caaaaacttt gttgaaaaac cagatccaag
    31141 caaagcacca agtgatttag ctattattgg acgttactta ttgactccag aaatttttga
    31201 tgtattgtcc gagcaacaac caggagccgg aaatgaaatc caactaactg acgcaatcga
    31261 tacattgaat aaaacacaac gcgtatttgc ccgtaaattc acaggtaaac gttacgatgt
    31321 cggtgacaaa tttggtttta tgaaaacaag tattgaatat ggtctaacac atccagaagt
    31381 aggtgcacct ttacgtgagt acatcctgtc tttaggtaaa acattagaag cagaaggaag
    31441 caagatcgat cataatccaa aaggaataac agaaatcaaa gaagaaaaga aaaaataacc
    31501 cttttttcta acgagcttca gctgctaatt gaataaaaag tagttgaagc tcgtttttat
    31561 ttgtttaaaa aacacgaaaa tgctatcctt atagaaaaga gagacaagaa gggagtttga
    31621 tcatgtcagg aggagaaatt gcaggattga tcgcagcaat cgcctttgcg atacttgtcg
    31681 tttttatcgt tcgtgtgttg ttgcaagttt ctaaaacttt agaaaaagta gatcagactg
    31741 tagcagaagc aaatacgacg atcgaaatcg tcacaaaaga cgtagatctt ttgtctagac
    31801 aagtagaagg cttactggtc aaaagtaatg aactgctctt ggatatcaat ggaaaagtcg
    31861 caacgatcga tccattgttc acagcagttg ctgatttaag tgaaagtgta tcagaactta
    31921 atcattctag taaaaacatc gcgacgaaag tcggcggaat cggtaaaacg acagctaaag
    31981 cgacggttgc cggaaaagtc ggtgggacag cgatgaaatt ttttaaaaac aaaaaacata
    32041 ctgaaacgac aggaggaaaa taaaaatggc taaaaaaggt ggatttttat taggtgcagt
    32101 agtcggaggc acagccgcag caatcgccgc gttattgtta gcaccaaaat ctggtaaaga
    32161 acttcgggat gaattagctg cccaagcgga tgatttgatg gatatggctt cagattacac
    32221 agatatggcg aaagaaaaat cgactgagtt aacaggtatt gcaaaagaaa aagcgcaaga
    32281 tctttctcaa caagcaggtg atctagcagg tagtgtcaaa caaaaagtaa gtgaatcagc
    32341 agatgaagca ggaagtgaat ctgacgatat cttgttaaat cttaaagaac aatcagctga
    32401 cttatctaat cgtttcaaaa aaacggcaga agatatgaaa aaacctgcag atgaattagg
    32461 aagtattgct aaagatactt cagaagatat catgattgat gtaaaagacg ctgctggtaa
    32521 agcaggagat actgtcaatg aaggaatgtc agaagcaaaa ccagttgcag atgactcaaa
    32581 agaaatgatg aaaatggcaa aagaagatgc gaaagaagct aaaaaagaaa taaaagatac
    32641 aatgacagat tcatctacaa atcactaaaa tcacaaattt atagaataaa aaggtgggag
    32701 cggactagct ctcacctttt ttactcttat ttttctaaaa caagtaattc ttttggtgta
    32761 gtcgtgaatg gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct
    32821 actttttcag gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact
    32881 aagtcatttc cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct
    32941 aaacggtgat tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga
    33001 tcaagttcac ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca
    33061 agagtgatgt tgtagatttt ttcttggaag tcggttggtt tttgataagc aattgtacga
    33121 gtagcatcac tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc
    33181 ggtgaaatct tcgtatttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg
    33241 actaatgtgt cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcaatttct
    33301 gcaatgatcg cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca
    33361 acatcggccc atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt
    33421 tgtagacgtt ggatgatgga agttagatca gtgtaagaat ccgttcccgt caagatatca
    33481 gagatagcat cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc
    33541 tgaccatagc gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa
    33601 tagccacgga catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga
    33661 gtgaaaagga aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga
    33721 tcactttcgt atccggaaaa gtaagcgatg tggccagggt cgctgatata agacaattcg
    33781 acttggtgtt gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa
    33841 cctactttct aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa
    33901 cgttctaaaa actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat
    33961 tcttgagatt atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata
    34021 aaatatgaat aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag
    34081 agaggcaaat gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgttaa
    34141 accagcaaca agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc
    34201 agttgcgcgt ggcttggcaa gtaagaaaac aacaacagtt ggtgtaatca tccctgatgt
    34261 cagcaatatg ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa
    34321 atacaatatt atcttagcaa attcagatgg caacgaccaa aaagaagtca atgtattgaa
    34381 taacttactg gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga
    34441 aatccgtgga gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc
    34501 agatgaacaa gtaggtagcg taaacattga ttatgtatcc gcaacaaaag atgcagtaaa
    34561 caaattggca aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc
    34621 catcaatgga caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc
    34681 atatagcgaa ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt
    34741 cgatcggatc cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat
    34801 cggtattttg gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat
    34861 cacaagtaac aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca
    34921 accattatac gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga
    34981 agaagtcgaa gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa
    35041 ataataaaag gacaaccatt cagaggttgt gtgcctgccg tttaactctg cgttacaagg
    35101 agcaatttca aaaaacagca tctcatgttt gatgaatatt gtgactcgtg attcggagtt
    35161 ggcaggagaa caccgtttat ttgggaaaag gggttatgac aaaattttgt tataatcctt
    35221 tttttgtgtc ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta tataaaacaa
    35281 tccgtgtata gatgctgcat tttgttcacc accatcaaaa aaataaggga ctgtgacaat
    35341 actattgtca caatccctta ttactgtgta ttctattaaa tcaatcatct ttctcatctg
    35401 attctttagt tgcttgattc gctcttgcat aagctgaagc ggtgttccag taatctgtat
    35461 agttttcatc ggtaccgcca acgccaaatt taaaggcgct tttcttcggt ccatttttcg
    35521 cccatagcga ttcaactgtt tttcctggtg tttggatgga ttttttattg acagtaactt
    35581 ttccaggtgt ttgaccagta aatccagata cttttttctt catcacatca gatgataatt
    35641 cgaatttctc atcagtgcca aaaatgtcag gttttgcttg gtaagcttga ttgatcagat
    35701 tggcaagata attagccgaa cgtatccttg ctttgctgtc cattccagta ttgtcatcgt
    35761 gccctgccca gctactgatg gtaatagacg gagtagagac aattagccat gaatctcggt
    35821 attcattggt agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc
    35881 ttgagatggc atctttgaat ggtgtagtga tttttgcatt gatcacacta cgcatcatgt
    35941 cattcatgat cgatgccgtt gcttccgaat agatccggac agagttgctt tcgtgtttat
    36001 aaattacatt tcctgcgtta tctgtgatgg aatcgatgat atagccttct tcatagacgc
    36061 cgccgtttgc taaagcctga aatccgttgg tctgttgaag cgtcgtgaca tctactgtac
    36121 ctaaaggagc agattcaacg ccccaattgt catttgccgg gtagttcatc tttgccaagt
    36181 agtgctcgta agcatattgt ttcgatccac cggaattcaa cacatcttga tataagtgat
    36241 aagccgggat attgttggac cattctagtg actcacggac ggtttggaag gtgttcgatc
    36301 cttcgttagt agcattgacg attttctcgc cagcattttc tccttcttgc caagttgttg
    36361 cataatctga tacacgggat tctgatccga taagccccat gtcgattgca ggtccataaa
    36421 caagaactgg tttgattgat gagccagctt gacgttctgt atcgaaggca tggttatttt
    36481 gattctgact gtaattccgt ccgccaacga atccgtagat gcggccagtt ctgttatcca
    36541 tcaatacatt tccggtttct acttgactgc cagcaccatc atctaacatg tatccataat
    36601 tttcaacgcc attttgcaat gcagcataga catctttatc gattgtcgaa tggattgtat
    36661 atcctttatt ttggatcgtt tgctgtgcct tttgataata agcgtcactg accgatgaat
    36721 cagacatatc agcgttgtct ttttcagcca attgttgtgc aatgattctt gttgcttcat
    36781 tcatcacagt ataatacaag aattctctgt cagtctgttc tgcgatttgt tgtggtagaa
    36841 agtcttttgt aaggtcatag gcttttgctt cttcgtattg ttctttcgta atttggcctt
    36901 cacgatacat actgaataaa acaaaatctt ttctggcaag gccggcagaa agatcttctt
    36961 ttagcgcgcc tgtgttcgtg tatggactat acgtgatcgg gctttggggt aatccagcga
    37021 tataagcagc ttgcggcagc gtcacatctt ttgcatctac accaaagatt ccttttgcag
    37081 cttcctggac tccagcaatg ttttgtccct tattattacg accaaatggt gagacattca
    37141 aatacgtagc aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaatga
    37201 tctcgtttgc tttacgtttg aatgttgttt catctgtaag gatctgctgt ttgactaatt
    37261 gctgtgtcaa agttgatcca ccagaagagc caataccagt agcttcagat actaatgctc
    37321 gtaaaacagc tttaggaacg taaccttggt gtttatcgaa gtattcatcc tctgtgctga
    37381 taattgcagt tttcaataaa ggtgaaatct tatcagatga aatagtcgtg cgcatcagat
    37441 ctgtctggat ttttgatatc tctgtattat ctgcataaac aatctttgac gtttctgtaa
    37501 tgtttcctag ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct tcgacgagat
    37561 aggcaaaata gccagcgcct attccaatac ctagagctgc gaacatcaaa agaagaacag
    37621 taataaaaac agtcaatgat tgaaaaactc taaaaataat cttaggaaca aaccattttt
    37681 ctttttttct tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa
    37741 ctaatggttt tatttcgcta attatagcaa ataatagaac aaaaaaacag acaaggctgt
    37801 ttttggcagg aatttctttt ttaaaagagt taaaacgtga gaaaatgatc tttattataa
    37861 aagagttctt aagcttttct ttagagaaaa tttcagttac tatggagaac agggcaaaga
    37921 aaaatcaatc attttctttg tatatcatct taccaatata taggaattgt tagtaacaat
    37981 tgcctttcaa ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag
    38041 aaaatgctgt taggagcagc agaagaagca gccagttatg gatcttcgac ttttatgatc
    38101 tatacaggcg cccctcaaaa cactagaaga aaagccatcg aagagatgaa tattgatgcc
    38161 ggaaaagcgt acatggcaga aaaaggtcta acaaatatcg tcgttcatgc cccttatatc
    38221 attaatttgg ggaatacgat caaaccagaa atgtttcctt ttgccgtcca atttctgaga
    38281 gaagagattg ttcgtgcgga agctttaggc gctactcaaa ttacacttca cccaggtgct
    38341 catgtagggg caggaacaga agccggaatt gctagaatta ttgaaggctt gaatgaagtt
    38401 ttgacaaaag aacagacggc acaaatcgct ttggagacaa tggcaggtaa aggtacggaa
    38461 atcggtcgaa catttgagga attagcgcaa atcatcgatg gagtaaaatt gaatgaaaaa
    38521 ttatccgtta cttttgacac ctgtcatacg aatgatgccg gttataatat taaagaagac
    38581 ttttcaggtg taatggaaga gtttgataag atcatcgggt tagatcggct taaagtactc
    38641 catatcaatg attctaaaaa tccgcaaggt tcgcataaag accggcacgc caatattggt
    38701 tttggaacaa tcggattcga cacgctgaat aagatcgtcc atgatccaat gtttgacaat
    38761 atttcgaaaa tcttggaaac tccctatgta ggcaaagata aaaagaaagc ttacgcacca
    38821 tatggaaaag aaatcgccat gttcaaagcg caaacattcg atccagaagt gtttcctgag
    38881 ttattagcag aagaagtgat actctaagat tttctatctg acagcagcaa aaaaggacca
    38941 ggcacattgc cttgtccttt tttgtttaag aaacaaagga gtactttttg cagtcttttt
    39001 catcatgcat cttctccccc ctctttttaa atttagacaa acaaggtata ctggtagaaa
    39061 agtaaaaaaa cgaaaagttt cacaagcaag tggcaaaacg tgattggaag gacgaaaaga
    39121 tgctgaacac tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca tactttattc
    39181 ttggcatagc cctattattt acaattattc gtttgtattt atatagtaaa gcaatctatg
    39241 gaacagacat gtcggcaacc tatgatgacc agctgctgat tcgctatgct caaaatattt
    39301 tggacggtaa atggctaggg gagtatacga ctacaacact ttccaaagga atctcctaca
    39361 gcttattttt agtacttgca cataaactgc atctttctta tgcagttttg ttcggcatgt
    39421 tcagtatttt tgccagtata ttggttgcac tcgcgtttaa accgattgtg aagaacaagt
    39481 atcttctttt aagtatctat ttttattttt tgttttctcc gattagtttt acacatgaat
    39541 attccactcg aacatatcgt aatgccctcg tgattccggc tgttgagatc attatcgctt
    39601 gtttattagc tatttattac cgcaaatacg gttctagcag aaaattgctg ccatggtttt
    39661 tagggctttc tgtcgctttt cctttctttt ggttcattcg cgaagattct atctggcttc
    39721 ttccttttac tgtagtagct ttgggtatca gtttcgtcca gatcttgcta gggcaagact
    39781 tttctttcaa agaagtaaag aagttaaaaa aacgactctt tcttctctcg aaacgggaat
    39841 ggctgaaact ttcattgttt ttacttccta tagttggctt ttccatcgtc tatcaatgga
    39901 tcgaatataa aaatgagaca acatacggta ttgcaaccat caatgaccgt tccagtggag
    39961 aatttggacg tttgatgaaa caactgatcc gaatagatga tgaaacgaac ttgaataaag
    40021 aaaacagtga gatatgggtc tcacatgctg cactaaataa agcattagcc gcatctccta
    40081 cattccatac tgtttctacc cgtattgacg aattatatac gactcacgcg tggactcaag
    40141 gtggaaaagt aaaagaatta cccggagata tcatcttttg ggcattgcga gatgtggtaa
    40201 gcgaatctgg ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg aaaaaagtca
    40261 accaagaatt agaagaagcc tatcacaagg gaacaatcaa aaagaaaaaa gagttctatc
    40321 tgatgggatc aggagatgga aagacgatga gtgatctgcc aatcgtattc gatttccttc
    40381 aatcaggata cgcttatgca tggcgatata aagatttcca tcaaggagga aattatagtt
    40441 tcggaacgca agaacaagtc aaacaggctc aagaattatt aaaccttccg ctaatggaga
    40501 attggatcga tagtaatgaa ccgagaacac ctaatttcca attaacaaaa tcagcaaaag
    40561 tcgcgaatgt catcataaaa atttaccaag ttctggctat tcccgtgctg attgcttcaa
    40621 tagcagggat attacttatg atactaggaa ccgtatttgc aaaagctgat cgtgcctatt
    40681 atagttcctc tttgattgtg gtcaccggat taatactgac acaattggtt tttcttttcg
    40741 gtgtctcatg gttttgttct tatgcgccag aaaaaaagga ctatttttta agtgtctaca
    40801 ctggtgcagg cgtgccatta acgcaattca tcgtagtaac aagcatgcta gttttcagta
    40861 aattaaatct gaaaaaagct ttatcttcta aataaaaaga cccttggtag ctagattttt
    40921 aacctaacta tcaagggtct ttgtgtggaa aaatcagttt ttattcgatt tcttctaccg
    40981 tttcctgcaa aagctgttca tattttttgt ttcctttata taaatcacca atcgtccatg
    41041 ccaacaggag aaggacaaga acaatgatta cataagcgat gtgatcagcc aatgctagtt
    41101 gagcggaagt ggcttgctcg ccgaagaaac tttcgatctg tcctggtaat cctcgtaagt
    41161 tcaagtaagt tagactaatc acagagaacc agccaagaag ttttacgatg aatgaatttt
    41221 taaatcggct acccatctcc gcttggctgt tggtcatcat cagtaaagga atcatcgaaa
    41281 acggcaacgc aaaagccaag aacacctggg attcattcat taagttattc aaagcggcat
    41341 gttcttcgat cgttcctttt gtacttgtaa acaaaacaca aatcaataca ggaatcacag
    41401 aaagcaatcg tgtgaccagt cttcttagcc aaatcgggat acgcatatgg atgaatcctt
    41461 ccatgatgac ttgaccggtc aacgtaccag taatagtaga gttctggcca gaagcaagaa
    41521 gtgctacagc aaataaagtg gacaagatac cagattttgc tacagcaatc aaaataccat
    41581 tgctcatagc tgatggatca gataaagctt catacagacc aaaaaaggaa ggatcttgga
    41641 cagaaccggt tttgaagaca gcgacaccca tgatcaatag cagtgcattg actagaaaag
    41701 ccattgacaa ctggatatta gaatcccaag tagaaaaacg tacagcttgt gctacatctt
    41761 cttcgttttg gtgatcgatc ttccgagttt gtgaaactgc tgaatgaaga tataagttat
    41821 gcggcatgac tgttgcacca ataatcccta aagctccagt cagcggagtt tcgccgccga
    41881 tgaccggtga gtctgagaat gtatgactgt tagggataaa gccagcaaat aaactgtgcc
    41941 aatctgggtt agacaagcca acttgataga caaaaacgaa taaaatgacg aaaattaagc
    42001 agacaaccag tgcttcgatc ttacgaaacc cgacttttgt cagtagtaag agaacgaaaa
    42061 catctaatac agtaataaag acggcaatca ccaatggaat atcaaaaagt aagtagaggg
    42121 cgattgctgc accaatgact tctgcaatat ctgttgccat aatggctaat tcagtcaaga
    42181 tccataaaat gacacctaat gtcttacttg tgcgtgctcg gattgcctgt gccaaatcca
    42241 tttggctcac gattcctaat tttgctgcca tatactgtaa aagcatagca atcagactag
    42301 acatcaaaat aactgacatc aataaatatt ggaaattttg tcctccggtg atcgaagtag
    42361 accagttacc cgggtccata tacccaactg ctactaacgc accaggtcca gagtaagcaa
    42421 gaagtgtttt aaaaaaactt ttcccctttg gtacatcaac tgttccattt acttcagcta
    42481 aagataaacc atttgtatgt tcaataagtc gatgcttatg aaattgttta ttggattgat
    42541 tattcaagaa aaaaccacct ttcctattta tctacgatta cattctacac ctcaaaaaga
    42601 aaaaattaaa gaaaaagatt cggtacgcct aatttttttt catggcgcgt cttgctagat
    42661 gacgaaagaa attttgttct cctctaaaaa aaccactatt ttttgcatga aactaaagaa
    42721 tacgcctttc ttttttcaat aaactttagt aaaataagtc attgagagca attcggaaat
    42781 agaaaggaga gatttatatg ttatcaacag gtattgtcgt acttattgct attattgctt
    42841 tgctaatcgg cgcagtaggt ggctttttcc tagcgcgtaa atatatgaaa gactatttag
    42901 aaaaaaatcc tcccgttaat gaggacatgt tgcgatcaat gatgatgtca atggggcaaa
    42961 aaccatctga gaagaaaatt cgccagatga tgcagcaaat gaagaaccaa gggaaaaaat
    43021 aggttctgac ccaacgactt tttacgggct gattttttca gtccgttttt tatttcgtaa
    43081 tttgttagac tattcagatt attcagcaaa aaagacaagc acagacaatc ctaggctctt
    43141 gataaagaca aaggaggagt aaaatgtcga tttttagaaa attaggctgg ttttttcgtc
    43201 aggaaaagaa acattattta attggggttt tctcgctatt cgcagtggcc ttggtacagt
    43261 tagttcctcc aaaagtgatt gggatcatca ttgatgagat cgccgataaa aatttatcaa
    43321 taaagatcat tttcgggtgg atcttcctat tgattatcgc tgctttttta caatatcttt
    43381 ttcgttatat ctggcggacg aatatttggg gaagtgcagc tcgattggag aaagaacttc
    43441 ggcagcagtt attcaaacat tttacagaaa tggacaatct cttttaccaa aaatatcgga
    43501 ctggggattt gatggctcac gcaacgaatg atttgaatgc gatccagaat gtagcaggag
    43561 ctggtatctt gacctttgca gattcagtga ttacgggcgg aacaacgatc attgcgatga
    43621 ttttgtttat tgattggcgc ttaacactga ttgcgctgat tcctctgcct ttgctggccg
    43681 tcacttcacg agtgctgggg tcaaaactcc atgatgcttt tcgtgattcg caagaagctt
    43741 tttctagtat caatgataag acacaagaaa gtatcactgg gatcaaagtc attaaaacat
    43801 ttggacaaga aaaagaagat ctagcggatt ttgaagaaaa gattgaagat gcaattatta
    43861 aaaacaaacg agtcaatttt ttagactcct tatttgatcc attcattacc ttgattatcg
    43921 gtctgtctta tgttgcaaca attattttag gtggaaagta tgtcttggaa ggcacgatct
    43981 cgatcgggca gatggtctca tttattagtt atatcggtat gcttgtttgg ccgatgtttg
    44041 cgattggtcg attgttcaac gtattggaaa gaggaaatgc ttcttatgat cgcgtcaatg
    44101 aacttttgca tgaaaagacg catatcgtgg aacaactggg tgcagtgcag accccggcaa
    44161 aaggcgagct gaatgtagct atttcctctt ttaattatcc gaaagaagaa tcaccagcat
    44221 tagaacaaat caagtttgcg atccaagaag gagaaacatt aggtattgtt gggaaaactg
    44281 gtgcgggaaa aacgacgatc atcaaattac tgatgcgtga atacgatgat tatcaaggga
    44341 aaatccaatt tggcggacgt tcgatcaaag aatattcatt gaatgcttta ttaggatcaa
    44401 tcggctatgt gcctcaggac cacttcttgt tttcgatgac cattcgagat aatatccgtt
    44461 tttctaatcc aaaactttca gaagaagaag tagagcatgc ggcttcttta gcatttatca
    44521 acaatgaaat caaggaatta ccaaaaggtt atgatacctt agttggagaa cgtggagtct
    44581 ctttatctgg cggacagaaa caaaggattt cgattgctcg agcattgatc aaaaatcctg
    44641 aattattaat gttagatgat gcactttctg cagtagatgc caaaacagaa gaagctatct
    44701 tgcataattt aaaagaaata agaaaagaga aaacaactat cattgcagct caccgtttaa
    44761 gtagcgtaat gcatgcaaaa gaaatcattg ttgtcgatca agggaaaatc attgaacgag
    44821 gaacccatca tgagctgctt gcactaggcg gctggtatga acaaatgtgg gagaaacagc
    44881 aattagaagc gaagatagaa ggaggcgagg cctgatggat gaaaattatc aatcggaatg
    44941 gacaaaatcg attccactta aagaacagaa aaagatcatc acacgactga tgaagttcgc
    45001 caaacctttt agaagaacgt tcatcgttgc tatcttattt gcgtttgctc tgtctgtgat
    45061 caatgtccta ttgccaagga tcatccaaac ttttatggat gatcatctgg ctaaacagtc
    45121 ggctacgaca caagttattt tgttttttgc tggtatgtac ttatttggag tcatagtaaa
    45181 aagtatcatt tggtttttcc aatggtattt gtattccatg gcttcattga agacctatca
    45241 gtatattagg gtaaaattat ttgaaaagct gcatacacta ggtatgcgtt attttgatca
    45301 gacaccggca ggttcaaccg tttctcgagt gacgagtgac acagaaacgc tatttgaatt
    45361 ttggtacgtc tttttgatgg tattgactgg gatctttgca gtcgtttctt cattcattgc
    45421 catgtttcaa atcaatggag aaattgcctt gtggactttg gtgttcttgc caattttagg
    45481 aatcgtcatc tggtattacc agaaatttag ttctcgtatt taccggaata tgcgagaaaa
    45541 attaagtcag ctgaatacga aattgaatga atcgatttcc ggcatgcgta ttatccagca
    45601 gtttcgccaa gaagctcgtt tagctaaaga atttgaacaa gtgaacaatg agtatttaga
    45661 cacgcgttat gcgatgatga aaacgaattc gattctatta agtccgatca tcaattttct
    45721 atatgcactg gcgattgcgt tggtgttgac tttgtttggg atcgatgcgt tgcattctcc
    45781 catagaagtt ggactgatct atgcatttac gacctatgtc cagggatttt ttaatccaat
    45841 gtctcaaatg atggactttt tgagcatctt cacagatggg atggttgctg gtagtcgtat
    45901 cttgaagatt atggatacag aagaatatgc accacaacaa aaccctggag cagatcaaat
    45961 gattacttca ggtaagattg agtttcgcaa tgtaagcttt tcttatgatg gagagcacaa
    46021 tgtattaaac aatatctctt ttgttgctaa tccgggagag accgttgcat tagtgggaca
    46081 caccggaagt gggaaaagct cgatcatcaa tgtgttgatg cggttttacg aattttatga
    46141 aggtcagata ttgattgatg atcatgacat tcgagaatat ccaatggaag agttacgtaa
    46201 gaaaatgggg ctggtcttgc aagatgcttt cttgttttat ggggatatcg caggaaatat
    46261 tcggatgatg aatccagcta tcacagacga acagatacgc catgcggctg agtttgttca
    46321 agcaaacaaa ttcatcgatg aattaccaaa aggatatcac tcaaaagtga tcgaacatgg
    46381 tgccagctat tctagtggac aacgacagct gatcactttt gcgcgaacaa tcgtgactga
    46441 tcctaaaatt ctagtattgg atgaagcaac agcaaatatc gatactgaaa cagaaggatt
    46501 gatccaagaa ggattggcga aaatgcgaca aggacggaca acgattgcga ttgcccatcg
    46561 gctgtcaacg attcgagatg cagaattgat tttagtttta gacaaaggtc atatagtaga
    46621 acacgggaat catgaaacac ttctagcgca aaatggtttg tatgcagata tgtacaaact
    46681 gcaaagcagt ggtatataaa agatgttgtg acagtagcat tttgacctaa gcactagagt
    46741 gaaaataaaa catagcttcc catatttttc atctgtgaga gttagtgtcg tagttaccag
    46801 atttaaaaaa gacgacgcca gctagtcaga agtgcctagt agcccctaag aaagcgttga
    46861 caaaatcgtt tgctttcgat aatacaaaga aaacgataca acttggatag tgattgccta
    46921 atgcaagcta aacctgatga gtctcccatg gtttcatgga cggctttttg ggtttttctt
    46981 tttgttttgg atacagccct atatatcatg gaaaggagca aaacatgctg attgagaaag
    47041 tactgaataa caacgtcgta ataaccaggg atgaaagaaa tcaggaaatg atcgtgatgg
    47101 gaaaaggttt ggcattcaaa aagaaagtgg gtgacccgat ttttgactca tgcatcgaca
    47161 aaaaatttca gttgacaaat gacggacttt cacaacagtt ccaagaattg gcacaagcga
    47221 ttcctcttga gtacttagaa atttcttgtg aaatcattga atatacaaaa gaggatctac
    47281 aagtccattt gaatgattct gtgtatattg cattgacgga tcatttgtat acagctatcg
    47341 aacgtcaaaa aatggggatc tttgtgccaa atgtattgct gtatgatatc aaacaactgt
    47401 ttcctaaaga gtatgccatt gggaaaaaaa cagtgaagaa aatctcggat aaataccaca
    47461 tcaagttatc agaagacaaa gccggattta tcgcattgca tttagttaat gcacaaggca
    47521 ttcaaagcca gcaagacaat acctacctgt ttaccacaac aatacaggat attttaaata
    47581 tcgtccgctg ttactataag attacttttg atgaagattc agtccatttt tttcgatttg
    47641 tcacacacct acgttttttt ctgacacgtg ttctagatgg agcgaaatca gaagatggag
    47701 aagtttctga ggaattgttc caagttattc aaaaaaaata taaggatacg tttggttgcg
    47761 ttgagaaaat agcagacttt ttaaccgggg ctttcgacta ccagatgtcc acggatgaaa
    47821 aaatgtattt aacgatccat actgcgcgtt tagtgcatga gaatcgttgt aaataaataa
    47881 aaaggaggac aaattaacac gaacgtatga aataagggta gtgacattca gttggctaaa
    47941 ccttccacta attaattgga gggaacagaa atgggaaaat accaagaatt agcgagcaaa
    48001 attgtagaaa atgtcggcgg gaaggaaaat atcaatggtt tgacacattg tatcacaagg
    48061 cttcgtttca aattaaaaaa cgaagaaaaa gcaaatgatg agatcttgaa aaatatggac
    48121 ggtattgtga cggtaatgcg agcgggagga cagtaccaag ttgtcatcgg gaatcatgtg
    48181 cgagtcgtgt ttgaagaggt tataaaagca ggaaacctta cttttgatga ggctgtttca
    48241 acagaaaaaa tgagaccgtt tgatatgctt attgatggaa tatcgggatg tttccagcca
    48301 ttccttgcta tcctggctgc tggtgggatg attcgtggac tgacagcatt acttgtcttc
    48361 ttaggcgcgt ttgatcgcgg ttctggaaca tttgttatgt tcgacaatat cggtgattct
    48421 gtattccaat ttatgcctgt tattatcggt ttaacagttg cccgtaaatt taaagtaaat
    48481 gaattcgtag ggatgttgct tggcgcagca ttaatgaatc ctaacttgtc gctggaagtt
    48541 ttgagtggtg cagcagaagc accactgacg accatatttt ctggtactat ttttgaagca
    48601 cctatttatc aaacagtatt tggcattccc tggattgcgc gtaactacgc ttcttctgtc
    48661 attcccatta tctttattgt gttgttagct agccaaattc agaagccaat taaaaagtta
    48721 gtacctgaga tgatcgcgaa tttcttcgtt ccattcttca ccgttcttat tacaatgccc
    48781 ttaggttttt tactcgttgg accagcattc acattcgcaa ctgatatttt aatggctgga
    48841 tttgaaacac ttttagcact ttcgccagtt aattatggag caatcgtagg cttcttctgg
    48901 caaattctgg tgatgtttgg tctccattgg gcaatcgtac caatgggatt gatgcaattt
    48961 tctgtgaatg gctggcaaaa tatcatgaca cctgttgcag tagtgtcttt tggacaaact
    49021 gcagcactta ctgcactcta ctttaagctt agaaacccaa aagacaaagc aatcgcaatg
    49081 ccagccattg tttctggtat tgtggggatt acagagccag ctatttatgg gtttacattg
    49141 ccacgtaaaa aaatatttat ttttacctgt gtcggtggtg cgttaggggg cgcgtatagt
    49201 gggttaatga atttaacttc ttggaatcaa ggtggactag gcatctttac gattcccaac
    49261 tatattagac cagatggtga tttaacagat gtgattaatg tattaattgg gatcgccatt
    49321 gcgatggtgg tatcctttgc gctgactttt ttcttttgga aggatgaagc aggtgaaaca
    49381 gatgatatac agaaaagatc gggtaaagaa attgtaaaaa caccgataca aggacaaatc
    49441 gctccactaa atgcagcgaa ggatgcagct tttgctcaag gaacattagg tcgagggatc
    49501 ctgatctacc ctgaaaaagg agaagtacgt gccccttttg acggaacagt tatgaccctg
    49561 ttcccgacga aacatgcaat cggaatggtt tctgaaacag ggctggaatt gctgattcat
    49621 gtcggattgg atactgtgca gttggaaggg aaatattttg aaagcttagt gcagcaagga
    49681 gaaagagtga aacaaggcga cctgttgcta cgcttcgaca aaaagaaaat cgaaaaggaa
    49741 ggatacagtt tagaaacacc tgtgatcgtc accaattata cggattattt ggatattttg
    49801 gaaaaccaag gggagacggt cgggccagac gatgcactta tcaccgcact gacctgaacg
    49861 gttaggtgaa gaatggacta ggcttaacta ttctttttat tccacttctt tattttcaaa
    49921 attgaaaggc tctttcatga tggctgagct gatagggcgt ttatcgaatt tttgaccgac
    49981 agaaattaga tggactaaat tctgctgata attttctgca aaaacacaac tatataacac
    50041 gtctagaaga taacaaattg atgtattgat cgtaaaatta ccaatttttg aatacagtcg
    50101 ctcgcgtgtc gtaagtcgca aagcggctgt actcattgca gatagcgttg aatcaccgat
    50161 actggtcaaa gctaaaattg gaacatcatt ttgtttcaat atttctgcgg tacgaaggat
    50221 cacattgttt tcacctgtat aagaaatcag aatcccgcac atatcgctcg tgcaattgta
    50281 cgcttcatag aatgattcac caaaagtggt gacaattgtg acatccattt tgatgcgctt
    50341 cattttcagc atgaaatctt gagaaatcaa agtattcgag ttactggcga agatcacgat
    50401 tttttttgcc tggagcagta aatacttagc tttttgcagt tggtcatgat gaatgagaga
    50461 aagtgtatct tgaatcgtca tctgttctaa agaagccatt ttatttgcga tcgtcataat
    50521 accgtctgtg gtggaaaaag gaagattcgc atctacgtct tgaaaattcc cttcaagata
    50581 ggctgtttca gctaaaaaag cattacgaaa actgacccag ccatcaaacc ccattttttt
    50641 tgctacacgg atgagtgtgg acgggtggac ataacatcgc tcagcgatct cttggatggt
    50701 catttcgcca agtgctggag aatcgcttaa gagaaactgg atcacttcat tttctgaagg
    50761 agaaaaggag atttctttga ttttttcacg taataacatg tagatacctt cttcttattt
    50821 ttttacgtaa attataactt ttttgaaaat gatttgtaaa cggatttata ctatataact
    50881 taaaatagac attttttgac aagatattta caaaaatcca ctagaaaaca gtaacttttg
    50941 taaatgttac tggaaagaaa cggatttcta ttgtttgttt tgtttacaaa aaagataatt
    51001 aaagtgtaaa aaagtaaagg agtgagaaca tggcaaaagg aatcaaaatc gctacgattg
    51061 gtggaggcag cagttacacc cccgagttga tggaaggatt tatcaaaaga tatgaggaat
    51121 taccgatacg agaaatctgg ctcgtagatg tagaagaagg aaaagaaaag cttgatatcg
    51181 ttagtcagat gtctcagcgt atgtgggatg cttctccgta tgaagtcaag atctatgcaa
    51241 ctctggatcg ggaagaagca ttgaaagatg cggattttgt tacgactcag tttcgtgtcg
    51301 gtcaattaga tgcacgaatc aaagacgagc ggatccctag ttattacggg atgatcggac
    51361 aagaaacaaa tggtgctggc gggatattca aagcttttcg taccgtgcca gtggtcttgg
    51421 caatcgttga agacatgaag cgtttatgtc caaatgcttg gctgatcaat ttcgcgaacc
    51481 caagtgggat ggtgacagaa gcagttatca gatatggtaa atgggataaa gtgattggat
    51541 tatgcaatgt gccagtaatg gcgatgatga cagaaccagc aatgcttggc aagaaaaaag
    51601 aagagctgat ctacaagttt gccggtctaa atcatttcca ttggcacaaa gtagcagata
    51661 ataaaggaaa tgaccgcacg gcagaattga ttgatcgttt atacgatgaa gacaatggat
    51721 tgccgaaaaa tatctttgat atcccgtttt tcaaagaaca attaaaacaa atgaacatga
    51781 tcccttgtgg ctaccaccgc tattactatc gtgaagaaga aatgctggaa catgctttag
    51841 aagaatatca aacgattggt acaagagcgc agcaagtgaa agaaacagaa gcagagctgt
    51901 ttgaattata caaagatcca gaattagacc ataaacctga acaattgcaa aaacgaggtg
    51961 gcgcttatta ttcagacgct gcctgtgaaa cgattacttc aatctatgga aataaagaaa
    52021 cacagatcgt tgtatctaca aagaatgatg gagctgttcc tgacctgtcg gcagattgtg
    52081 ttgtagaagt cactgcctat gttggcgcac aaggagcgag aaatgtagcg tttggttctc
    52141 ttcctgctgc tgaaagaggc tggttgcagg taatgaagaa tatggaattg ctgacgatcg
    52201 aagcagctgt gactggtgat tatgggacag ccttacaggc gtttacgatc aatccactta
    52261 tacgatcagg aaagacagca aaacggatca tggatgagtt gtttattgca caccagcagt
    52321 atttaccgca attcaaggaa acaatcggcc gattaaaaga agaaggaatc gaagttcaag
    52381 atgaactggc aagagaatta tcaagtaata cacatataat ggaggaagta taatgggatt
    52441 cagaaaagat tttttatggg gcggtgctac agcagccaat caatgtgagg gcggttatga
    52501 tgaaggtgga cgcggactag caaacgtaga tgttgtgcca atcggaaaag accgttttcc
    52561 tgttatcacc ggaaagaaaa aaatgtttga atttgatgag gaccattttt atccagcaaa
    52621 aattgcaatc gatatgtatc atcgttataa agaagatatt gctttgtttg cagaaatggg
    52681 gttcaagact tatcgaatgt ccatcgcctg gagtcgtatt tttccaatgg gggatgagaa
    52741 agagccgaat gaagctggct tgaaatttta tgaggatgtc tttaaagaat gccaaaagca
    52801 cggaattgag ccacttgtga cgattacgca ttttgattgt ccaatgcatt tgatcaaaga
    52861 atatggtgcg tggcgttcca gagaactcgt tggtttttat gaaaatctgt gtcgagtcat
    52921 cttcaatcgc tataaaggac ttgtcaaata ttggctgaca ttcaatgaga tcaatatgat
    52981 ccttcatgca ccattcatgg gcgcagggct gtattttgaa aaaggagaaa atgaagaaca
    53041 aatcaaatat caagcggcac atcatgagtt ggttgcaagt gccatcgcaa cgaagattgc
    53101 tcatgaagta gatccggaga acaaagtagg ctgtatgctg gcagcaggag catattatcc
    53161 atacacttgc aatcctgaag atgtttggga ttctagaaaa tcagatcgag aaaattattt
    53221 cttcattgat gttcagtcac gaggagaata cccagcttat gcattgaaag aaatggaacg
    53281 aaatggcatt cagatcgaaa tggaaccagg ggatgccgca ttgctgaaag aacatactgt
    53341 tgattttatc tccttttctt attattcttc ccgagtttcg actaccgaca acgaactctt
    53401 ggaacagact gcaggaaata tctttgcttc tgtcaaaaat ccatatctgc aagcaagtga
    53461 atgggggtgg caaattgatc cattaggctt gagaataacg atgaatgata tttatgatcg
    53521 ttatcaaaaa ccattattta ttgtagaaaa cggcttaggt gcagtcgata cgccagatga
    53581 aaatggttat gtggaagatg attaccgaat cgattacctg gcagcgcata tccaggcgat
    53641 gaaggatgca gtagaactag acggagtcga tctattaggc tatacgactt ggggatgtat
    53701 tgatttagta tcagctggta ccggtgagat gaagaaaagg tacggattca tttatgtcga
    53761 tcgtgataac caaggaaatg gcacattagc ccgttcaaag aaaaaatcat tcaactggta
    53821 taaaaaagta attgattcaa atggagaaaa tctttcgaac gattgatcaa tgatttataa
    53881 aagtctattg tttttcagcg gatttttcga gtataataaa gctattcgag aaacgcaagc
    53941 agaacaatag actttttttc gcattggctg taaagtatgc ttacttgatt aagtaaagga
    54001 gaatctacat atgtatgatg taatcgttat tggcgcaggt cctgctggga tgactgctgc
    54061 tttatatgct tcacgttcaa acttatccgt attgatgatc gaacaaggtg cccctggcgg
    54121 ccaaatgaac aatacggcag aaatcgaaaa ttatcctgga ttcgattcga tcatgggccc
    54181 cgatctagct tataagatgt atgaaagtgt ctcaagattt gggacagaaa atgcttatgg
    54241 aatcgttcaa gatatcaagg atcacggcag ccataaagaa gtcatctgtg aagataaaag
    54301 ttacgaagga aaaacagtca ttatcgcaac aggctgtatc caccgtaaat taggcgtacc
    54361 tggcgaggaa gaatttgctg gacgaggcgt ttcttactgt gcagtctgcg atggtgcgtt
    54421 tttccgtaac aaacgtctag tagtcatcgg gggtggggac tcagcagtag aagaagccat
    54481 ctatttgaca caatttgctt ctgaagtagt gatcgtccac cgtagagatg aattacgtgc
    54541 acaaaagatc atccaagacc gtgcatttgc aaatgaaaaa atttccttta tgtgggatac
    54601 agtcgttgac gaaatcgttg gaaacgaaat ggtagtgaca ggtgtgaaag cacgtaatgt
    54661 caaaaccggc aatgaatttg atttagcagc agacggagta ttcatctatg ttggactgga
    54721 tccattaact gcacctttta gagaagcagg tttgacgaac gaagctggct ggattccaac
    54781 agacaacgaa atgaaaacga atatgccagg cgtttttgcc atcggagatg ttcgtgaaaa
    54841 agatttgcga caaatcacta cagctgttgg tgacggcggt attgctggac aacaagtgta
    54901 taaatacttg gagtctttag aagaaacaac agcataagtt taaaaagagt gaaagaacgg
    54961 ttttaattgt tcttttactc tttttttttc gcgtgaaatc cactgaatcc gatttatgtg
    55021 aatacttgca atcatgcttg ataaaagaat cctttcttga tttaagcgtt ttttggtcct
    55081 catactttca tatctaataa gtgaatgcta tacttattaa gaaccatatt tcagaaagag
    55141 gtgttatttt catgtcttgg gaacaagtgt atgaacaatg ggtacatgaa gaaaatttag
    55201 aagaaaactt aaaaaaacaa ttaaatgatc tgggtgaaga tcctgaaaaa cttgaagatg
    55261 ctttttatgc accgttggaa ttcggtactg caggcatgcg gggaatctta ggacctggga
    55321 tcaatcgaat gaacatctat acggtaagac aagcaacaga aggactagca cgtttcatgg
    55381 atacacaagg tgaagaaaca aaacgccgag gtgtcgctat cgcttatgac tcacgccatc
    55441 agtcaccaga atttgcaatg gaagcagcca aaacactggc acatcacaat atcccgtctt
    55501 atgtattcga aagtctgcgt ccaacaccag agctttcttt tgcagttcgt catttgaaga
    55561 cgtttgcggg aatcatggta accgcatctc acaacccagc ggcttacaat ggatataaag
    55621 tctacggaga agatggcgga caaatgcctc ctgcagacgc agatgcattg acgaaatatg
    55681 tccgtgaagt cagcaatccg ctaaaagtcg aagtattatc tgacgaagaa gctaaacata
    55741 gcgggttgat cacgatcatc ggagaagaag tggacgctgc ttatctagaa gaaatcaaag
    55801 cagtgacgat tgatcgtgaa ttggttgaaa caatggggaa agatttgaaa cttgtgtaca
    55861 cgccacttca tggaacaggg aaaatgttgg gcgaacgcgc gttgaaacaa gctggattcg
    55921 aacaattcgt actagttccc gaacaagctg tggcagatcc agatttcact acggtcaaat
    55981 cgccaaatcc agaagaacat tcagcttttg aatatgctat acgacttgga gaaaaagaag
    56041 gagctgactt gctgattgca acagatcctg atgcagaccg tttaggcgca gcggttcgtt
    56101 tgccagatgg ttcttatgaa gtattgactg ggaaccaaat cggagcattg tttgctcaat
    56161 atattttgga agcacatcaa tcaagaggca ctttaccaga aaacgcagcg gtattgaaat
    56221 caatcgtttc cagcgaattg cctacagcaa ttgcggaaca ctacggtgct accatgttca
    56281 atgtgttgac agggtttaaa ttcattgctg aaaaaatcca acaattcgaa gaaaaccatt
    56341 cacatacttt tatgtttgga ttcgaagaaa gttatggtta tttagttaaa ccttttgttc
    56401 gcgataaaga cgcgatccaa gcattgcttt tattagcaga agtagcagct tactataaaa
    56461 aacaaggcaa aacgttgtat gacggcttgc aaacgatttt tgaaacctat ggctatttcg
    56521 cagaaaaaac gatttctgtg acaatgagcg gacaagaagg ttctgcgaaa atctctgctt
    56581 tgatggaaaa attccgtaaa gaagcaccga cagaatttgc cggagcaaaa gttattcaaa
    56641 cagaagactt taaagaattg acgagaacag accgtgaagg aaacgtagaa aaactcacaa
    56701 caccgccatc cgacgtattg aaatatacat tggaagaaaa tggctggatt gctatccgcc
    56761 cttcaggaac tgagccgaaa atcaagtttt atattggtgt aaaaggaagc tctacagaag
    56821 acgcagccaa aaaagtagcc tcttatgaag cgattatcaa aaagatgaca gaagaataaa
    56881 aaacttgaga ctgatggaaa aagtggtaaa ctttagaagt cagtcttttt tcaagttgga
    56941 ggtgaatgga ttgccagaca cgcaaaaatc aaaagtagag aaagtcagtc aattattcaa
    57001 aatgttgagt gatcccactc gtcttaaaat tctgctatat ctgaaagacg gggaacaaaa
    57061 tgtgacagca atcacccaag cagtggaaat ggagcagtct gctgtatcgc atcaactacg
    57121 tttattaaga gaaaatcatg tcgtcaagtc tcatcgcgag ggaaaagcga ttttgtatag
    57181 tcttgatgat tctcatgtac tggatatttt gaaccagaca ctcaaacatg tggaacatca
    57241 ataacgatag gtgcaaatag ataaacactg gagtgtgaca acgaaatttc ttcgttgtca
    57301 cactccagtg ttttttaaga aaaagacaaa aatgatcaat cgcttttttc tgttgtttca
    57361 gttccataat aactatgatc ttctaggtct aaagcattca aaataagcga agccgtttct
    57421 tcaatagata aagatgctac attgatcact acacatccta gtttttcata aagatcattc
    57481 gcaaaatcga gttcagctct aattttttcg atatcggaat aagcagtatc agggtttaat
    57541 ccgtaagagc gcatccgttc tttacggata ttatttaaaa tatctgggtt attcgttagt
    57601 cccacgattt ttttaggatc gatctcccaa agctgtttgg gaatatgtgc ttgtgggatc
    57661 aaaggtaaat tggcaacttt taaatttttg ttagctaaaa acaagctcaa aggcgttttg
    57721 gaagttcggg atacgcctag caaaacgaca tctgcttcta aaaaaccacg aggatctttc
    57781 ccatcatcgt attttacagc aaattccatt gctttgatcc gtttgaaata gttctcattc
    57841 aataaatgga gggcaccagg ttgccgaatt ggcttgatac cagttaaacg ttcaatttct
    57901 gatatcggtg gcgtcatcac atcaaaacta aataattgat gttcttcaca aaaagaacgt
    57961 gttatctcga tcagttcttg attgattaat gtatgcagga caagtgcttt ttcttctaat
    58021 gcatcttgca atgcctgcct taatgttttt tcatctgtca cgaacgttct gcggaatagg
    58081 ttgaactcaa cggtaggata ctgagccata gtagcttgcg ctagttttgt cgcagtttct
    58141 ccagcagagt cggagatgac aaaaaaagta acgatttctg tagaatcgga agtcatggat
    58201 aaaacctcac ttgcattttt tttatgttta ttataccata ctctagaatg cgtacttcgt
    58261 aatcattttg atttggagga ataagtcatg aaaaaacaga cattgatcga acaatcatta
    58321 gaaacattga aaaataacgg ttttaaatat actaaaaaaa gagaagcatt gttaacttat
    58381 ttagtgaagc gtaaccgcta cgtatctgct aaagaagttt ttgactatat gaatcaggaa
    58441 ttcaaagggg taagttatga tacgatttac cggaatctcc atgattttgc agagatcgat
    58501 ttactggaag aaaccgattt aaatggagaa atgaagtttc gttttcattg ctgtcagggg
    58561 gaaatcggcc atcaccatca ttttatctgt acagtgtgcg gaacaacgaa agaaatccat
    58621 atgtgtccga tgaattattt cgaagaacag ctaggtggat gcacgatcga agggcataga
    58681 ttcgagattt tcggaagatg tgaaaattgt caataaggat ttaaataaaa taacatttga
    58741 taatttaaaa aaaaagcaag atttccttga cggtcaaaac agcattagat ataatattta
    58801 caggacagtc ttgttttttg agatatattt caataacaat tacggttact ttttaagctc
    58861 ggagggaggg aattaacatg tcaaaaacag tcgttcgcaa aaacgaatca cttgacgatg
    58921 ctcttcgtcg cttcaaacgt tccgtgtcaa aagcgggtac tttacaagaa tctcgtaaac
    58981 gtgaattcta cgaaaaacca agtgtaagac gcaagaaaaa atctgaagca gctagaaaac
    59041 gcaaaaaatt ctagttctgt gatgaattgg agttggtagt gtgtcactac taagtagatt
    59101 aaacgatgac atgaaagcag cgatgaaagc gaaagataag gaatctttac aagtcatccg
    59161 aatgatcaag tcatctatac aaaacgagca gattaaagaa ggtcacgact tgacagaaga
    59221 agaagaacta acggtgttgt ctcgtgaaat gaaacagcga cgtgattctt tgcatgagtt
    59281 tgaagaagca ggacgtgacg atttagctga aaaagtaaaa agtgaaattg taatagtcga
    59341 aaaatatatg ccggaacaac tttccgacga agaaattcga caacttgttc aagaagcaat
    59401 cactcaaact ggtgcttcat caatgaaaga atttggcaaa gttatgggtg caattatgcc
    59461 taaagtcaaa ggaaaagcag atggaaacca agtgaatgcg attgtgaaag aactattaca
    59521 atcttaattt tatcatttaa actgcggaca gtgattatcc gcagtttttt gtgttcgtaa
    59581 aaaaagaact aaaaaacagc tagaagaaag aatcttattc tttcttctag ctgttttttt
    59641 cctgtttaat atctcttatg ttaaattgtg tttgatttgg ttattcttct ggtaactcac
    59701 ttgcttcttg tttatatcct gatacgcgat atacataata aaagagcaag ctgccagcgt
    59761 aaccaagcaa cgttgggacg acccagccaa gacctaatgc agcaaaagga acataatgat
    59821 gataaaatcc tagtaagctt gctacgacag tttgctgact cactaatgca ggcgaatttg
    59881 ccaacatatc caatacggct ggaacggcag aaaagaacat cgttacttga tagacaaatg
    59941 gactcttttg gaagaatttt gctgttaagg aaagtaagat taacgcaagt gacaatggat
    60001 acaaaagcat caatactggt aaagaccatt ggatgatatt atccaatccg gcattcgcaa
    60061 cgacaaaaga gacaaaagtc gttaaccgca gccatgtcat ataactgact ttagggaaca
    60121 gtttatggaa atcttgtgca aaagaaacaa cgagtcccat agcagtagtg aagacaccta
    60181 atgtgaccat tacccctaag aagctagcac cgaagttacc taaataaaaa ttagtgatct
    60241 gagaaagtgc agttccgcca ttttctgata aagacatctt attcaaactc atcgcaccga
    60301 gaaggaccag accaaaataa atcatgactt ctaacgcaac gctcaggcta ccagcttttg
    60361 ctgttaattc tgtgactttt ttatctttaa aaccaagatc acgaactgca tggacaaaag
    60421 tgacacttaa agcaagtaaa gctactgcat caaccgtgtt gtatccttct aaaacgccat
    60481 ttgtcaaagc gttcgtctga taagaatctg cagcagattg gtttagattc cccatgggtt
    60541 ggaataaaga aacgacaaaa atgatagcta ataatgcaag aaacaaggag tttaaatact
    60601 ttccgacata tttgaccaaa cgtgttggat gtacagtaag gaaataagca agtaaaaaga
    60661 aaagagcaga gaataaaaac atacctaatg aatcatattt ttcaggcaaa aagggtttag
    60721 cagccatttc aaaagcagtt gctgctgtcc gcggtgtacc aaagaatggt ccgatcgtta
    60781 aatgaacaag gatcaagaac aaggcagcat accattttcc gacaggttta gctaagtcat
    60841 acagaccatc actttttgtc actactacag ctaagatagc taataatggg aaaagagcgc
    60901 ctgagatggc aaatcctaca ccagcgctga tccagtttga tccagccatt tgacctaagt
    60961 gtacaggaaa gatcagatta cctgacccga agaacatccc gaagataagt gaactgacca
    61021 tcaataattg cttccatgaa taagtttttg tttcttccat aaatttttcc tccaataatt
    61081 atcattttga gtaacaaaat aaacgttgca gaaactagaa ataccactaa tatcagattc
    61141 catgaaaacc accaccttaa aatataaaaa aagccctttt ccacttggga aaagggctct
    61201 agattctaga acggtaccac cttttttcgc ttaaaaaagc ttcttcattc acggacgctt
    61261 ttcgataaag ttatccgcta gcctgataat ggaggcagcc acaatgatct acgttttcga
    61321 cattgactcg gaaatgatgt tcgtctattc gatttattgt catttctcac ttacatgact
    61381 cactgggaat aaatcactga atagcctact gttttcctcg acgctttgct gtatatttat
    61441 ttgttgacgt tataatacac ctgttttttt tgaaatgcaa gaatatttca aatattttgt
    61501 tttctttttt tgaaacaaga aaaataccca gagaatactt gctaagttag acggaatact
    61561 tgtcctctat cttatgcata gcttacatga tcagcttttt ttattcaaac gagaccttta
    61621 gagaatggaa gcggctagtt ttttaacgtt tcttggtact tatggttaag caactctttt
    61681 agaacctttt cttatttgct atatagtttc ttctgagtat ggtaaaatag gaaagaatta
    61741 atcgaaaaaa aggggatgtc tatttttgac ggaagagtct agttctttag agattagatt
    61801 gacggctgct gatgatgtca gcatgctttt aggtgcacac gacaagcata taaaactgat
    61861 tgaggaaaca acggaaacaa ccatccatac acgtggagaa atcattcaga tcattggtga
    61921 gcaatcccag atttccttgg ctgcctcagt cattcggaca ttacaggaat tgatcaaacg
    61981 aggaatccac gtaagtacgc ccgatgttgt gacggcattg aaaatggggc aaaaaggtac
    62041 attagattat tttgttgaga tgtatgagga agagatcgtc aaagaccgta atggaaaacc
    62101 tatacgggta aaaaacagcg gccaaaagaa atatgtcgaa tcggtagcca aacatgatat
    62161 cgtatttggc gtaggaccag ccgggacagg aaaaactttt cttgcagtag tattagcaat
    62221 cgctgccttg aaaaaaggtg aagtgcaaaa aatcattttg acgcggcctg ctgtggaagc
    62281 aggtgaaaat ctaggctttc ttcccgggga tctaaaagaa aaagtggatc cttatctgcg
    62341 gcctgtttat gatgctttat accaaatttt tggattggat catacgaacc gattgatgga
    62401 acgaggcgta atcgaaatcg cacctttagc ttacatgcgg gggcgaacat tggatgatgc
    62461 attcgttatc ttggacgaag cacaaaacac gacagtcgct cagatgaaaa tgttcttgac
    62521 ccgtctcggt tatcaatcaa aaatgattgt caatggggat acaagtcaga tagacttgcc
    62581 tcgagggacg acaagtggtc ttgttcatgc agaacgaaca ttaaagcaaa tcaagaaaat
    62641 cgattttgtt aattttgaag caagtgacgt tgttcggcac cctgtagttg ccgaaatcat
    62701 caaagcttat gaaaaggcag atctccatca agaataagct ttgcttagga ggataagcac
    62761 atgttgaata aaacactgca gaaactacaa gaaaaacttg gaaaggcagc attgcctttc
    62821 ctgctgttct tgttttttat cattatctgc ggcgttacat ttagtagtgt caaacaaaag
    62881 gtcaatgatt tcagagaagg ccaagtagca gaagaaagta tccgtgcgaa caaaacgatc
    62941 gagaacacgg aagaaaccga acaaaaaaga aaactggcag cagaagcagt cactccagaa
    63001 tacacttacc aaaaagatct tgcagatgac cagaacaatc ggatcaagca actatttgaa
    63061 ttgatcgata agacgaatga tgccatcaac aaatcttatg acgaaaagat tgataaggca
    63121 aaggaagatg aaaatatccc aaagcctact acagaagagc ggatcgccgc gctgaagaaa
    63181 aattttgaaa atgtgaatgc agaaaatgtt gtgttttatc aaaaactacc gaacaatttt
    63241 tattcgacga tatttgaaat gactgaaact gagattcata ctgtgaggga tgagagtctg
    63301 aagctcattg acgaacagat gagcaaacaa gttcgtgaaa gtgaattgga agcttttaaa
    63361 caagaagcag aagagcaaat ccaatatttg aatgtcacac cagcacaaca acaaatgatt
    63421 cgctacttag tggatcaagg tatcgtagtg aatgacgtat tgaatgagaa aaagacagaa
    63481 gaattgaaac aatccgcacg agaagctgta cagccagtga tgatcttcca aggagaaatc
    63541 attgttcgtg aaggtaatca aatcgatgct tcagctatga aaaaattgga attactagga
    63601 ctgactaatc aaacaacttc gatttttccg ctaattgcca tggttttagc tgttttgctt
    63661 caaatcggcg tactgattta taattcactt caattccaaa atgcaggaga aagaacaaaa
    63721 tacgtgcttt tctatgtgac agctatgtca gtcagcatag tgctgatgaa atttttccaa
    63781 ttattccaaa cggaacaagc tacttatatc ccgctgtttt atcccgctgc ttttgcacca
    63841 cttgttttaa gctttttctt gaatcgaaga gcagggatca tggctggtat tttccaagca
    63901 gtatccgcac ttttcatttt ttatgattcg attggcacga actttctaac gattatcttg
    63961 atgtcttatg ttttctctgg gctcatggca acgattgtca gacgcaaacg gatctcagaa
    64021 caaggattat ctgctgccat gtgggtcatt atttttcctg tgatgatgga tgtcattttg
    64081 atcgtctatc aaggaatgag ctttggtgat gcaacgactt ggttaatgct cgtctgcggg
    64141 ttcactggtg cactcttctc attcttgctg acgatcggtc tacacccata tattgaattg
    64201 atggtcaatg atgacagtgt aattgtatta aatgaactca gcaatccaaa tcatccttta
    64261 ttgaaacagt tgctggaaga agcgccaggt acttatcatc atagtatgat ggtagctaat
    64321 ctaagtgcta acgctgtagc agaaatcggc ggacgttctt tgctaactcg agtagcttgc
    64381 tattatcatg atatcggcaa gatcaaacat gctagctttt tcgttgaaaa cttgccttca
    64441 ggagcggaaa acccgcacaa tttcttattg ccagaagaca gtaaacatat tatctttgga
    64501 catgtgacag atggagccaa aatattggaa gattataata tgccgcaaat ggtgatcgat
    64561 atttgcaaac agcatcatgg aaccacgcta atgcgttatt tctacatcaa agcgaaagaa
    64621 cgcaatccgg aagtaacaga agagcaattc cgttatcctg gaccaaaacc gcaaagtcgt
    64681 gaagcaggga tcgtcaatat tgctgacagt tgtgaagctg cagtacgggc aatggatcat
    64741 ccgacgagcg aaaaaatcga aagttttgtc cataatctta tcgaagagcg tatttccgat
    64801 ggtcaattag acgatagtgg actgaccttg aaagaaatcc gaaaagtgga aaaatcatta
    64861 atcagcggtt taagtagcac cttccattct cggatcaaat atcctaaaat gaaaacagaa
    64921 gttgagaaga taaaggaaga acaagaagaa tagaaagaag cgatgtataa tggatattac
    64981 ctttatggat gaaacaaacc aagtctcaga agagaaaatg aaagaaatcg atgacttgct
    65041 gcaatttgca gcatcttatt taaagctgcc agaggaaaca gaaatgtctg ttactttcat
    65101 ggacaatgcg gcaatccaag taatcaatcg tgattaccgt ggaaaagatg caccgacaga
    65161 cgtcatcagt tttgctctgg aagaagaagg cgaagacgaa atcccagtga tttttgaaga
    65221 tggagagaat ccattacctc gtgtactagg agacatcatg atctctattg aacgtgctgc
    65281 tgaacaagca gaagcttacg gccattcata tgatcgggaa cttggctttt tagcggtaca
    65341 tggattcttg catatcaacg ggtatgacca tatgacacca gaagatgaga aagaaatgtt
    65401 tggtttacag aaagagatct tggatgccta tggactcaaa agataaaaac gtagagaaaa
    65461 acaaacattt cctgatgtct gtggaatttg ctgtccaagg agtcaaaacc gtttttgagg
    65521 aagaacgcaa tatgaggaaa catgttgcgt tcggtattct tgctttattt atgggcgtga
    65581 ttttccagct tgatcggata gagtggttat ggctgctttt agctgttttt ctcgtttgga
    65641 tagtagagat catcaatact gtttttgaaa atgtagtgga catgtttacg gattttcatt
    65701 ttcatccgat tgggaaaaaa atcaaagata tggcagctgg agcagtttta gtgaccgctt
    65761 gttttgctgt catcattggg ttgattttat ttgtccctaa aatatatcat ttgttgttta
    65821 attaaaaagg agaacgtata tgccagaaca taaatcaggg tttgtcgcaa tcgtcggccg
    65881 cccgaatgta ggaaaatcca cattattgaa ccgaatcgtg ggtcaaaaaa ttgccattat
    65941 gagtgacaag gcacagacaa ctagaaataa aatccaagga gtatatacta caccagaagc
    66001 tcagctgatt tttatcgata caccaggaat ccataaacca aagcatcgtc taggagattt
    66061 tatggtagaa gcagcttaca gtgcgttgaa agaagtggat gcagtcttat ttatgatcag
    66121 tgctgatcaa aaacgcggcc ggggagacga ttttattatt gaacgtctaa aaaacgtgca
    66181 ttctcctgtt tatctgatta tcaataaaat cgataagatc catccagacg agttgctggg
    66241 aatcatcgaa gattattcga cgcagatgcc ttttgcacaa gtgattccga tctctgctac
    66301 agaaggaaac aatgtcgaac gcttaatgga tgtattagtc agtgaaatgc cagagggccc
    66361 acaatatttt ccagatgatc aagtgactga tcatcctgaa tacttcatcg tttctgaatt
    66421 gatccgtgag aaagtcttgt ttttaacacg agacgaagtg cctcattctg tcgcagtcgt
    66481 tgttgattcg atgaagcgaa acgagaatga taaaatccat atccaggcca cgatcatcgt
    66541 cgaaagagat agccaaaaag gaatcattat cggcaaaggc ggaaaaatgc tgaagcaagt
    66601 aggaacgaaa gcaagaaagg atatcgaaaa tcttttagga gacaaagtat ttctagaact
    66661 ttgggtcaaa gtccaaaaag actggcgaga caaaaaagtc tatctgcaag acttcggcta
    66721 ccgaaaagat gaatactgat attctgaact tcttataggt taagtataga aataaactgg
    66781 ataaaaatcc gcacgttgag aaaaacggcg gaagatcgaa acataaataa tctggatcgg
    66841 cagaatctgc ttttccagat ttatttttta ggagggagaa tatgagccag cttgcagaat
    66901 cgaaaggctt gattttatct agccgtaatt acaaagaaaa agataaatta gtcaaaatct
    66961 ttacggaatc ttctggcaaa atgatgtttt atatcaaagg aatccatcgg caaaatcagc
    67021 cattagctcc ggctttgctc ccctttaccg aagcagtcta tatcggtaat tttcgaagtg
    67081 aaggtttgtc gtttttaagc agtgtcaaag acgtccatgc gtttcggaac atccaagaag
    67141 atatcttttt gagcggttat ggtacctatt tgctaaatct agtagatgca gcaatcgaag
    67201 atcatcaata tgacccgcat ttattccaat ttacgcaaca agctctgcag cggatggatc
    67261 aaggagatga tgcagaaatc atcacgaata tctttgaagt tcaaatactg caacgcttcg
    67321 gaatcgcgcc aatttggact cactgtgtcg tatgcggaga aacaaaagga aaatttgact
    67381 attcttccaa atatggcggt gtgatatgcg agaaacactg gccaatggac gaacaccgtt
    67441 atcatgcaga tcctcgtgct gtttatttcg tccgaatgtt ttcggctatt tcttatgata
    67501 agatcagtgg aatccacttg aaagaagaaa cgaagcaggc aatccgtgac ctcattgacc
    67561 agttgtatga tgaatatgtc ggtattcatc taaaaagcaa aaagttcatt gatcaaatga
    67621 agtcttgggc acacgtatta aagacgccag agaaaaatat gcctgaaaaa gagatacctg
    67681 aaaaagaaga ataaatgaaa gatacaacaa aaaaatcaaa actatttgac aaatacaggg
    67741 acttccgtct attattaacc gtagattaaa tagatcgttc actgagagga tctattatat
    67801 aaacaagaaa actgcaaaat gaatacgtac attgaccaag atcagtaaaa aacacgtggt
    67861 ttagcgagtt cgggagagtg gaagccggac ccaaacgatt tttgaagagg cacttgcgag
    67921 tacgataaat gaagctgccg aatctttatt cggaagtagg gtggaaccgc gaaattattc
    67981 gtccctatgt ctgtaatcag acatagggac tttttgtcgt tttctttcct gtattcttat
    68041 tgacagcaac gcttaaaaat tgaaaggggc aaaacagatg agtaaaaaat tgaccgtcca
    68101 agatatgatt ttaacattac aaaaattttg gtcatcaaac ggctgcatgc tgatgcaagc
    68161 ttatgataca gaaaaaggag caggtacgat gagcccatat acattcttac gggcaatcgg
    68221 accggaacca tggaatgctg cttatgtaga gccatcccgc cgaccagctg acgggcgtta
    68281 tggagaaaac ccaaaccgtt tgtatcagca tcatcaattt caagtcgtaa tgaaaccttc
    68341 acctgaaaat atccaagagc tttatttaga aagcttgcgt cttttaggaa ttgatccatt
    68401 agaacacgat attcgttttg ttgaagacaa ctgggagaac ccatcgatgg ggtgtgccgg
    68461 tgtgggttgg gaagtatggc ttgatgggat ggagatcaca caattcacgt acttccagca
    68521 agtcggagga ctaccttgta aaccagttac ttctgagatc acttatggac tagaacgtct
    68581 tgcttcatat attcaagaag ttgaaagtgt ctatgatctg gaatgggctg atggcgtgaa
    68641 atatggcgag atcttcaaac aaccagaata tgaacattcc aaatattctt ttgaagtaag
    68701 cgaccaagac ttgctactaa gtaattttga ccgttttgaa aaagaagcta aacgctgtat
    68761 cgatgaaaat cttgttcatc cagcgtatga ttatattttg aaatgcagcc atacattcaa
    68821 cttattagat gcccgaggtg cagtatccgt aacagaacga gcaggttatc tttcccgtat
    68881 ccgcaacatg gctcgtgctg tagccaaaat ctttgtggca gaacgcgaaa aattaggatt
    68941 ccctttattg aataaaaaca cagcaaatcc agaaaacatg aaggaggctg aataagatgg
    69001 caaaagactt attacttgaa atcgggctgg aagaaatgcc tgctcatgtt gtcacaccaa
    69061 gcatgaaaca attagaagaa aaaacagcaa aatttttaga tgaaaaccaa ttgacttatg
    69121 atacgatcga aacattttcc acaccgcgcc gtttagcaat caaagtaaca aatattccag
    69181 aacgacaagc ggacagcgaa gaagaagtca aaggaccagc caaaaaaatt gctttggacg
    69241 cagatggaaa ctggacgaaa gcagctgaag gatttgtccg aggacaaggt ctgacgacag
    69301 atgctatcac ttttagagaa ttaaaaggcg tggaatatgt ctatgtaacg aaatacactc
    69361 acggcaaaga agcaaaagaa gtattgacag gtttagcaga tgtcattaaa agcctcactt
    69421 tcccagtaac gatgcattgg gcagaatacg attttgaata tatccgccct attcactgga
    69481 tcgtggcatt gttagatgac gaagtaatcc cattcgaaat cttggatgtc aaaacaggca
    69541 aagcctctcg aggtcatcgt ttcttaggcg aagatgtaac atttacgcat gcaaaagaat
    69601 acgaagaaaa attaaatgaa caatttgtta ttgcttcacc gcaaaaaaga aaagaaatga
    69661 tcatcacaca agcaaacgaa ttagcagaaa aaaatcactg gatcattgat ctagatgaag
    69721 atttactaga agaagtcaac aatctagtcg aatatccaac tgtcttttct ggcgacttcg
    69781 aagaaaaata tctatctgtt cctgaagaag tactagtcac ttctatgaaa gaacatcaac
    69841 gttatttcga agtacggaac gatcaaggta tgttgcttcc tcattttatt tctgctcgta
    69901 atggcgatcg ggtaaaattg gaaaatgtgg tacgaggcaa tcaaaaagta ttgactgctc
    69961 gtttagaaga tgcggaattc ttttataatg aagacaagaa agcttcaatc gaccaatacg
    70021 ttgaaaaatt aaaaactgtt actttccatg aaaaaatcgg tagcatctat gagaaaatgc
    70081 aacgggtaca agtcatcgct cgcatcatag gcgaacaagt aggactatct gaggaagaat
    70141 tgatggatct gcaacgcgct gctgaaatct ataaatttga tctagtaacc aacatggtag
    70201 gagaattccc tgaactacaa gggatcatgg gagaaaaata tgctctgctt aaaggcgaga
    70261 aaccagccgt agcaacagcg atccgtgaac attacatgcc tatatccagt gaaggagatc
    70321 tacctgagac tacagtaggt tctgttttag cgattgctga taaattagat agtatctttt
    70381 ctttctttgc agttgggatg atcccaagtg gctcaaacga tccatatgct ttgcgccgtc
    70441 aagcatatgg tgtcgttcga atcatcgaat cgaaaaaatg ggcctttcct ttgtctgttc
    70501 tgcaagaaac gattagtgaa gttatcagta aagatacgga tcgttttggc attggcttgt
    70561 cagcgggaca acaacaggtg atcgacttta tcaaaggccg tctgcgccaa ttattgacaa
    70621 ctaagaatat tcgtcatgat gtcatcgaag ctgttttgaa cgcagaacaa aaagatctga
    70681 caaaagtatt tgcagcagca caattgttca agcagcatct tgcagatgaa gacttcaaac
    70741 catcgatgga agctttgaca cgtgtcgtga acttagcgaa aaaagcggag cttgaaaaac
    70801 aatcagaagt agaccctgaa ctgttcgaaa acgaagcgga gaaagaactg cacaaagcag
    70861 tagaggcaat gaaaacaagc tttgctgacc aaacgatcaa cgaaaattat gatcagcttg
    70921 taagccttcg cccactgatc gaaaattatt ttgatcagac gatggtcatg gcagaagaac
    70981 cagcagtacg taagaaccga ttaacgcaat taagtcaaat tgctgccatg gctttgtcac
    71041 tagcaagttt agatcaaatc atcacaaaat aatttctaat atgtaaataa accagagaac
    71101 aggcacaaaa taggctattt ctctggttta tttgttataa atataaataa ctattattaa
    71161 ttcaatgtta attttttttg ttattttatt ttttgtgtaa cttttaaaaa cacctatgaa
    71221 aattaaggaa ataaaaatga aatcgattaa ttgttatctt attaatgttt tatttatttt
    71281 taaatcgtaa attgccctag tcaagaaaac agtttgtggt atgattatat agggaaaact
    71341 tgtttacaaa tatttctgtg aatatattag tttaattatg ttttttaaaa taaaaagctg
    71401 tcatttttat gtaagtgaat tatatcttaa tttatctatc atcaatactt aggagtgaat
    71461 ctatggaaaa gccattcgtc aagtcattga ctgctgtggc ggtaggtgca ggtgctattg
    71521 cgatctgttt gtttggttac catatcaata atcagcggca acatcagcaa cggatcaatt
    71581 atgcagaatc tgccatcacc aatcaaaaag acaccttgac ttctttatca aaagaagtag
    71641 acaagctgta tagtacaaaa gaaaaaaatt ttctaaaccc tgaaataaca gaagaaacaa
    71701 tcacaagttt gtcaaataag ctatcctctg tcaaactttc agcagatgat tacgacatca
    71761 aagaatcaga attgcctaaa gaagctgttg caatccaaga tgagaagaaa gcaatcgtga
    71821 cacagttaga tagtgcagaa tcaaaactga agatccagac agctgtcaac gatttattta
    71881 ctaaaaatgt atcaaactgg cagcaagctg tagacgatgt cgtcatcaaa gaaaaggtga
    71941 caagtgcaga tgtcgctcgt gtacgtgaaa atatgagctt ttttaaagat agtccttgga
    72001 aaacgattgt tatgcaatat ctaggattcg ctgatactca gatcgcgcaa gtcacgcaac
    72061 tagatcagtt attcgatacg atgttgaagg atggtcaagt gactgccacc gctacttacg
    72121 atcaatattt gacggtgctc agtcaaatag atcagatccg gaatgaaaaa atacgcgcag
    72181 catacgcaac aaaagcacaa actgttgctc agcaaatggg ctatagcaat ataagctatt
    72241 gacagttaaa acgttgattc aagcaaggtt agcaaacgga ggaaactatg gcaagacgaa
    72301 gaagaaaatc aagagggaaa aaaatatttc tgattatttt agcagttctt atcgtattag
    72361 tattagcaat tgtaggagta ggagcaaaat tatatctgga tctctcacat tctattgaga
    72421 aaacttacga atcagtggaa cgaacccaag gagaacgaac gaaaccagtt gatctggaca
    72481 aacaagaatc tttctctgtt ctattgatgg gcattgatac tggagattta ggtcgggtcg
    72541 atcaaggaag atcagatacg atgatggttg ccacagtcag tcctgaagac aaacagacaa
    72601 cgatcgtcag cattcctcga gatacgtatg tcgacatcgt aggtcgtgac acaaaagaca
    72661 agatcaacca cgcttacgca ttcggcggag ctgccatggc gatggatacc gtacaaaaat
    72721 atgtagacat cccaatcgat cactatgtct ctatcaacat gaaagggcta aaagaacttg
    72781 ttgatgcagt tggtggtatc gaagtcaata atgacctcac tttctcacaa gatggctatg
    72841 actttacaat cggtaaaatt actttgaacg gggatcaggc attatcttat tctcgtatgc
    72901 gttatgaaga tccaaatggt gactatggta gacaagagcg tcaaagaaag atcgtagaag
    72961 gtgtagcgaa aaaagtattg agtctaaacg gtgtcagcaa ctatcaatcc gttttgaatg
    73021 ctctagagtc gaatatgaaa acagacatga gctttgatga aatgaaaaaa attgctttag
    73081 attatcggga ggcatttggt acgatcaagc aagatcagct gcaaggagaa ggcttcatgc
    73141 aagataatat ctcctatcaa aaagtcagcg atcaagaact tgatcgtgtg aaaaaagaat
    73201 taaaagatca aatgaatcta gagaataaat aggaaagtgg agaaaaaatg gaagagacaa
    73261 tcagcttgaa agaaattttt gaaacattac gcaaacactt ggtaacaatc atcatctcaa
    73321 tgtttgctgg cttggccatc tcaggaatcg taacattttt catcttgaca ccaaaataca
    73381 gttcacaagc acaattgatc gtgacactgc cacaatcaga cacagcaaat gtcaatgatg
    73441 tcaatacgaa cctgcaaatg atcaatacgt ataaagatat gatcgtcagt gatttagtgc
    73501 taaatgaagt caaagatcgt ttagaaacag aagacaatgt gaaaatgact gctgaacaaa
    73561 tcaaagaggc catctcagtc aatcagtcac aaaattcaca aatgttctcg atccaggcaa
    73621 taagcacgaa tgcagtgact gctcaacaga tcgctaacac aacttcacaa gttttccaag
    73681 agaacgcaaa agacgtgatg aatgtcgata aaatctcgat tatttcaggt gcagttgcca
    73741 atacgacacc tgtttcgcca aataataaat tgaatttagt gattggctta gtattaggaa
    73801 tgatggtagg cgtaggtctg gcattcttat tcgaattact cgatcggaca gtgaaagatg
    73861 aaaaatatgt gacggataca ttaggattcc caatcttagg aacagttcca gaaatgtcag
    73921 cgaaagaatt gaacgctggt atccgtaaaa aaggatcagc tcctgcacga ccaaaagcta
    73981 caaatggtaa aacagcgcca tcacgcagaa gccgctcaag agtctaggag gaagaaaaat
    74041 ggcacgaaca cagaaacaaa aagcagcaca aactcatgca gtcagtttga tcacattaac
    74101 aaacccatct tcaccaatcg ccgaacaata tcgtacgatc cggacgaata tccagtttgc
    74161 ctccgcagct ggtcagcaaa tcaaaacgat tgtcgtgact tcatcaggtc ctggagaagg
    74221 aaaatccacc actgcagcaa acattgcagt cgtttttgct aaatccggtc aacgggttct
    74281 attagtcgat gcagatttac gtaaacccgt cgtctataaa acattccagt tgagcaatgc
    74341 tagtggatta agtacagcac ttagttcatc aggaagtgta gcagatgtga tccaacgaac
    74401 gccagtcgag aacttgtcga ttttgcctag tgggcctaag ccacccaacc catcagaatt
    74461 gttaagctcg ccaagaatgg atcagattct agccgaagca agacagatat ttgacgtggt
    74521 gatattcgat atgccaccag tagtagccgt aacagatgca cagatcatgt cttcaaaaac
    74581 ggatggcact ttattggtcg tacgtgaaaa tacatcacgt aaagaatcct tgtctaaagc
    74641 aaaagaactg ctagagatgg tacaagcacg agtcttaggt gttgtataca acggagcaga
    74701 acatagcaaa gatgctggtt attactacgg aaattaagga ataagaagag aggagacaag
    74761 agaaatgatc gatctacatt gccatatcct accaggaatc gatgacgggg cagaaaactt
    74821 agaagcaagt attgcaatgg ctgaaaaagc gattcagcaa ggcatcacgc atattttatg
    74881 cacaccacac cacaataatg gaaaatacag caatgaaaaa tcacaagtca tttctctagt
    74941 cgcttcgtta caagccgaat tagagaaaag acaattgcct ttgacgttat tggaaggaca
    75001 agaagtacgt attaccggaa cgctcatcga agacatccac cgagatgaaa ttttatttac
    75061 agatttagat gatacatatc ttctgatcga atttccgaca ctggaagtgc cgttatatgc
    75121 agaacggctt ttttttgagt tgttagaact aggaaagaca ccagtgatcg tccatccaga
    75181 acgtaacgcg cattttcgta aaaacccgaa ttatttgctt ccgttcctag atatggggtg
    75241 tttggcccaa cttactgcgc caagttatgt tggggtgttt ggcaaagaca tccagaaaac
    75301 agctaaaacg atggtcaaac ataatctcgt gcagatggct gcttctgatg cccatggggt
    75361 ctctaagcgc accttttact taaaagagtg ctatgagcag attggcaagg actttggtaa
    75421 ggaaaaagta gtacagatga aacaagtcgc aaaggatctg atcaacgggg atgaaatcag
    75481 ttatccagtc tatgaagagg taaaaaagaa gaaatttggt ttattttagg gggaatgtag
    75541 ggtgtttgta ttaacaagaa gaagaaaaat tgccacattg gttgttgtgg acagcttgtt
    75601 attaatcgct gcaaatattg cagcagctaa attcatgaag ccgtttgtag ctataccaat
    75661 ggaccttatt ttaatctcta ttggtttgtc gattggtttt tatttatttt atggtagttt
    75721 atttaaagtt ttcactcgaa tcaatcgcta tacaaattta agagagatca ttgcaatttt
    75781 tagttcacta tctgcaagtg ctgcctcaag tatcctcata ctgctgttca ttaatcggcg
    75841 atacagttta cggttagtta tctttgctta tctgctttcg ctcttattga tcatcggtag
    75901 ccgattgatc tggcgtatct acatcgaaac aaaaaatatg agatatgtat cagcagattc
    75961 tgctaaaaat acattgattg ttggtgctgg cgaaggcggg cgtattttat acaacagctt
    76021 tcttggatcc aaaacggctc aagatatcca cgttgtcggg ttcgtagatg atgatccaaa
    76081 taaaagaaat acgtatcttt caggaaaaaa agtattaggt gcattaaaag atattccgga
    76141 attgattgaa aaatatgaca ttcaaatggt aacgatcgct atcccttcct tatcaagaaa
    76201 aaaattacga agaatcttcg agttagtcga atccgctcgt gtgaaagtca acacgatgcc
    76261 ttctatagaa gaacttgctt caggaaaaat tagcgtatca aaattaaaaa caattgacgt
    76321 agtggattta ctgggaagag atgaggtaaa gctggatatt gaatccatca aagatcagat
    76381 cacagacaaa gtcattcttg tcaccggcgc aggaggatcg atcggttcag aaatctgtcg
    76441 gcaaatcatt caattcaatc ctgcaaagct attgctttta ggacatgggg agaactcgat
    76501 ctacttgatt gaccgtgagt tacgcacgca tcatcaaaat tgtcctacag aaatcgtacc
    76561 gatcatcgca gatatccaag atcgcgagaa aatcaatgag atcatggaac aatatcatcc
    76621 agatatcgtc taccatgcag ctgctcataa gcatgtacca ctgatggaat ataatccaaa
    76681 agaagcagtc aaaaacaata ttttcggtac aaaaaatgta gcagaagcag ctaaagcagc
    76741 aaaagtgaaa aacttcgtca tggtatcgac agataaagct aacaatcctc caaacgtcat
    76801 gggttcaaca aaacgaatcg ctgaaatgat cgtgactgga ttgaatgaag aaggctgtac
    76861 gaaattctca gctgtcagat ttgggaatgt ccttggttct cgcggtagtg tgattccagt
    76921 attcagagaa caaattgctc aaggtggtcc aatcactgta acagactttc gtatgacccg
    76981 atacttcatg acgattcctg aagcgagtcg tttagttatt caatctggcg cattagcaaa
    77041 aggtggcgaa atttttattc tagatatgag tgaaccagtg aagattgtag acctagccaa
    77101 aaacatgatc cgattgagcg ggtatagcga agacgaaatc gaaatcattg aaacaggtat
    77161 ccgtccaggg gaaaaactat atgaagaact attgttggat aaggaaagaa atgatgaagc
    77221 agtttatgag aaaatctttg taggaaacat caaaggttac tcaatacaaa aagtgatgga
    77281 ttttgttaag agcctgccac aagacgatga acaactggct aaagacattg tcacttttgc
    77341 aaatgcttcg aatagatagg agattaaaaa ttgaatattt taatattaag ttgtggacgt
    77401 cgttgtgaac tagtgaatgc atttaaaaca gcattaaaca ataatgaaat ggaaggaaaa
    77461 atcattggag cagattgctc tgaactagca cccgcactat atatgtgtga cgaaaaaata
    77521 gtattaccta aagtttcaga aagtaattat attgaggaat taataaaagt aataaagttt
    77581 tttgaaatta aattaattgt tcctactatt gatactgaat tatcaacatt atcaagaaat
    77641 aaaaaatata ttgaaaatga aacagactca gttgtattag tttcttcaga aaaagtcatc
    77701 gacatttgtg agaacaaaat tttaacttct gctttttttg aacaaaatgg ttttaaaact
    77761 cctgaaattt taaactcttc tgaaattaca aaatttcctg tatttataaa acctctgaat
    77821 ggtagttcat ctgttaacac atttattgta aataatgaaa aagaattgtt gttttttagt
    77881 gaatatatag ataatcctct tattcaagag tatattttag gtgaagaata tactatagat
    77941 gtttgcttaa actttgattc gacaccagta agtattgttc ctagaaaaag aatagcaact
    78001 agaggtgggg aaatactgaa gggtcagatt attaaagata gagaactaat tgagactacg
    78061 aaaaagatgt tggaaaaatt aaatgcaatc ggacatatta ctattcaatg tataaaaaac
    78121 gaaaagggaa tattttattt agaaataaat gcaagatacg gtggaggagc ccccattagc
    78181 attaaatcag gagctaattc ccctgaatat attataaaga tgatagattc aaaaaaaaat
    78241 ttgagataca gagaaaatta tttagataaa atgatagcac tgagatatga tcaagcgatt
    78301 tatttagatg aaaaaggaaa tgtatataat gattaaagcg gtgatctttg atttagatga
    78361 cactcttgtg tctgaatatg attatgtaaa aagtggatac aaatgtgtag ctagaagatt
    78421 agcagtgcaa aaaattttcc cggctacttt tgacgaaata tatagagtcc ttttagatct
    78481 ttttgctgaa gatagtaaaa atgtatttaa tcgtctatat gactattttg aaattcctta
    78541 tagtaaaaaa gaaattaaag aactggtaaa tgtatatcga gaacacaaac cagacataaa
    78601 ttttttagaa aatgcagata ctttattaac ggaattaaga agtagaggat acaagctggg
    78661 gattattaca gatgggtatg ctataaccca acgaaacaaa ttggatgctt tgaaagtaga
    78721 ctatttggta gattatattt gtattactga cgaattaggc cgtgaattgt ggaaaccaca
    78781 ccctatctca tatcttttat tgttagaaaa gtttaattta aaggcacaag agtgtatata
    78841 tattggcgat aatgagttga aagattttat aactgccaaa tcaataggaa tgcaaacaat
    78901 taaaatagaa agagtaaatg gtatttacag agaaagcagt ttgaagttca aaagatttta
    78961 ccaagctgat aaaaaaatac gttcgttatg ggagataaaa aattttttgg gagtgatttc
    79021 atgaaaagta aaagaattct attagcttct ccacatatga gtgaagaagg atatgaaaaa
    79081 gagtatgtaa aagaagcatt tgatacaaat tgggttgctc ctttaggtgc gaatgtgaat
    79141 ggatttgaga aagaattagc agaatacgtg ggagctagtc atgctgccgc attatcttct
    79201 ggaacagcag ctatacattt agctttgaaa gcggctgggg tcggtaaaga tgacatagtg
    79261 atttgtcagt ccttgacgtt ctcagctact gctaatccaa ttctctatca aggagctata
    79321 cctgtatttg ttgatagtga ttacgaaact tggaatatga aacctgaaca tttgcgaaca
    79381 gcactagaaa aatatcctaa cacaaaggct gtattagtag tacatttgta cggtttatca
    79441 gctaatttag acgaaattac taaaatatgc aaagaatacg atgttactct aattgaagat
    79501 gctgcagaat cattaggaac aacatataaa ggaaaatata ctggaacatt tggcgactat
    79561 ggaatttatt cttttaatgg aaataagata atcacaactt caggtggcgg aatgcttgta
    79621 tccaatgaca aagaaaaggt ggaaaaagtg agattttggg ctacgcaatc tcgtgagaag
    79681 gcacgccatt atcaacacaa tgaaattggc tataattatc gaatgagcaa tatcgttgct
    79741 ggtatcggtc gaggacaatt gaaagtatta aatgaaagaa ttgagaaaaa acgatatatt
    79801 catagttttt ataaaaaaga attgtctaaa ttgtcaaata tacaattcat gccagaaaat
    79861 aattggaatg aaccgaatta ttggttaagt gtcataacaa taaagggaat aaatgcgaat
    79921 catcttattg atgagttaga caaaaataat atagaagccc gcccagtatg gaaacctatg
    79981 catttacaac ctgtttttaa aaattatgat tatattggcg atgatgtagc agaaacttta
    80041 tttgacttag gagtatgttt accatcagat acaaagatga cagatgaaga tttaaaatat
    80101 gtagtatcta cgattaaaag agtgatcaat gatgcgtaaa aaaactttct atcagctttt
    80161 tgggaaaaga attttagata tcctattgtc aggaattgct ctcatcgttt tatcgccgat
    80221 aatcttaatt gtaggttttt tagtaagaat taaacttggt tctccaatta tcttcaaaca
    80281 agaacgacca ggaaaaagtg aaaaaatttt ttccatgtat aaatttcgta caatgactga
    80341 cgaaagagac cacaatggag aatatttacc tgatgaaatt cgactaacta aatttgggaa
    80401 aatgcttaga gcaacaagtc tggatgagct acccgaactt tggaatattt tgaaaggtga
    80461 tatgtcgatc gtaggacctc gtccattatt agtggagtat ttgccactat atagtgagaa
    80521 gcaacggaaa agacacaacg taagaccagg attaactgga ctggctcagg tcaatggaag
    80581 aaatgctatt agttgggaag aaaagtttga tttagatgtt tattatgttg ataaaattag
    80641 tttctttaat gatcttatta ttataattca gacatgtaaa aaagtaatca agaaagagaa
    80701 tattaataca atcaataaca atatcccaga aaaatttaaa gggagttaaa tacagcagct
    80761 taatgcaagt tttgtgactt gcattatatt taggtataaa tcaaagcgag tatattagaa
    80821 ttatataaca tatgttaaaa aaacgtatag ctaataaaag tatgatttta aaaatttgtg
    80881 tagagtttta aatatactgt ttcaatacga gaaaattata aaaaagtata aggaaaagag
    80941 agttatggca aagtattata ataaaaaaat tcttataatg gcaaacaacg atgatggtct
    81001 ttaccgtttt cgaggaatgc tcataaaaaa cttagtagat caaggtaatg aagttattgt
    81061 atctcttcca aagggcaaga atattcctaa attaattgaa cttggatgtc aaattattga
    81121 aactccaata gatagaagag gaattaatcc aaaaactgac tttaaactat tttttaacta
    81181 ttgtaatatt ttgaaaaaaa taaagccaga tatggtcatt gcttatacta tcaaaccaaa
    81241 tatatacggt ggattggcat gtcggttaag aaaggtttct tatgcattaa atataaccgg
    81301 attaggaacg gcatttcaaa aaaagggggt tttgaaaagt ctcattgtat ttttgtatag
    81361 attagcagct aaaaaatcta aggtcatatt tttcgaaaat tttgaaaata tgaaaacatt
    81421 tcagacttta caaattgcta aacaaagtaa atacaagcta ttaaacggtg caggagtaga
    81481 tgtagaacac tttagttatt tagaatatcc taaagatgag caagttcatt ttttatttat
    81541 tggaagaatt atgaaagaga aaggtgtaga tgaacttttt gaagcaatga aaaacttata
    81601 tagtgaagag aaaaattgtg tacttgatgt ccttgggtat tttgaagaag attacggcat
    81661 aaaaattgaa aaatacgaaa aagagggatg gttaaaatat catggatatc aatctgatat
    81721 tcgtcccttt gtagaaagag cacattgctt tgttttgcct agttggcacg aaggaatggc
    81781 aaatactaac cttgaatcag cagcatcagg gagaccaatt attacaagtg atatcccagg
    81841 gtgtaaagaa gcagttattg aatcgaagtc tggttattta tgtgaaagaa aaaatagttg
    81901 tagtctctat aattcgatga ataaatttct aaaattatca tatgagcagc gcattaacat
    81961 gggaaaaatg gggagaaatt atatgattaa aaaatttaat aagaagaaag ttgtcgatga
    82021 aacaattaaa tcattattta gttaaaaaga tatgttttgc aaagtatgtg atagaaaaga
    82081 gggattctgt ggcttcagaa tagatatcaa agaattggca aaagtttctg atattttttt
    82141 atttactaca ttacaagaag gaatgccaag atctatgatg gaagctatgg caagtggatt
    82201 gccatgtata gcaagtaaaa tccgaggtaa tgtagacctt ttagtggaag gaaaaggtgg
    82261 atatcttgtt ccagctaaag atgcagaatt agtagcagag tgtttgagag aactaatcaa
    82321 taataaatct cttagaaagt atatgggaaa tgagaacctt tccagaatta aagaattcga
    82381 ggttagtatc gtaaaaaaaa gaatcaaaga aatatatgaa gaagttatag gtgagagtgt
    82441 aaaatgaaaa atccaatgtt ttcaataata gtacctatct attgcgttga aaaatatttg
    82501 aaagattgct tagattcaat aagaaatcag acatttaaaa attttgaagc aatactagtt
    82561 gatgacggta gtcctgacga atgcccagaa atatgtgact attattccca aatagatgga
    82621 cgtttaaaag taattcataa gaaaaatggt ggaataatag atgcacggaa aataggagtc
    82681 actagtgcta tgggagagta tatagttttt ctagatggtg atgattggct tgcaaatact
    82741 tatttagaaa aatatgcgga agtaattact aagtacaatc cagatataat atgtagtggg
    82801 tattttgcat cacgttccaa caaaattaga aaaagagaat tgtcttgctc gtttggatat
    82861 tatgacaaaa ataaaattat aaatttgatt tatcctaaat taattgagga tgaacatgga
    82921 gaatatttta gtccacaatt atgggcaaaa gcttttagaa ctactctgta caaggagcaa
    82981 caacaagtat ctgggcaagt tagtgttggt gaagatcatg catgtacaaa accatgtatt
    83041 taccatgcaa attcgatata tatgatggaa aaatgtttat attattacag aataaacgaa
    83101 aattctataa caaaaaaacc acaaccatat tattgggaag gaccaaaggc tattggagag
    83161 cattttgaaa agcagattga tatgaataag tatgattttc aagatcaagt atatagaaat
    83221 gttacacaca atttatttaa tgttgctgtt tcacaattta ataaacagga caaatattta
    83281 aatataaaaa aagatattat acaaaatcta agtgacgaat actatactag agctatttgt
    83341 aaatgcaaat ataaagataa ttggaaagga attagtgcta agtttgcatt gaaaaacaaa
    83401 tgggtatttt taatttatat ttataacaaa ttgataaaga ggtaataata atgtcagtta
    83461 agattagtgt aattgtacct tgttataatg ttgaaaaata tattgatgag tgtataaata
    83521 gtttgataaa tcaaacattg aaagatattg agattatttt gttaaacgat ggttcaacag
    83581 ataatacgtt ggcgatatta aagaaatatg aaaagcttga ttctagaata aaagtttacg
    83641 aacataaaaa tatggggtta gggccaacta gaaatcgagg gattaaaata gctaatggag
    83701 aatttttggc ttttgtggat tctgatgatt ttgtttccaa tactatgttt gaaagtttat
    83761 ataattgtgc aattgcagag aatgcggaca ttgcaattgg agaagtaggc attttttctg
    83821 atagagaaat agaaagagta aaaataagaa aaagtctaac gaacttaaaa acaattgaat
    83881 tagcaacata taataagaaa gaatttttta agcaattcta tttcaatcgt ttatattcac
    83941 ataatgcttg ggataagata tatagacgta gtttagtatt agagtttaat ttatcatttg
    84001 gtgataacaa aataattttt gcagaagata attggtttca attacaagta tttatgacaa
    84061 atacaagaat ctgtttcgta gataaattgt gttattatta tcgccaacaa aataattcta
    84121 taatgcataa gccaaaaagt aatttggttt ttagacatgg aaatatgatt gctgattatg
    84181 aaaagttgat aaggcaaaat ggaaacaaca taatagataa aaaagcttgt atgttggttg
    84241 catttgatgt actaattatg gagattttta atcaaaaaaa cgttggtgga acatgtgaag
    84301 attataagaa tgcattagtt tctttgaaac atcataaaat attgagagaa aatatttcaa
    84361 atatagttag aatgaaagca tatgaacttg aacctaatat gagaaagaag ttagcccttg
    84421 tgaccattag tataatgttt aattttaaaa tgtataaaac agcgtataat atgctctgga
    84481 gaatatataa tcgataaaga ggtaggaaat atgaggaaat tgacctttgt gataggaatt
    84541 atgggaaaag gaggggcaga acgagtaatt gcgaatttgg caaataattt tattcaagat
    84601 aactgggaaa ttgatattat aactatatat gggaatcggc aagactatga actgaataga
    84661 aaaatacagg tacatccaat aatatgtaaa agttcgtttc gtgcatttag acctttggaa
    84721 cgctttaagg aacttaggaa aaaaataagg gaaatacagc ctgatctggt tatttcgttc
    84781 cttgctgatg taaatatcca tgtcattatt tcattgttag gagtaaaaca aaaattaatt
    84841 gtttctgaac gaaatgatcc acaacggaat ccagaagaac catggattag gaaaattaga
    84901 gattttcttt ataaaaatgt agatggaatt gtttttcaaa caccagacgc aaaaaaatat
    84961 tttagtaaga tcaatgataa aaaagtaaaa acaattataa ttcccaaccc aataaaggaa
    85021 aatttacctt attataataa aactacaagt agtaaaaaat ttattactgc atgtagattg
    85081 gataaacaaa aaaatttgcc cttaatgatt gatgcaatag gaaaacttat tcatgaagga
    85141 tatgagtgtg aactggatat ttatggagaa gggggattaa aaaccgagct tgaaagttat
    85201 atcaaccata atggattaac agaatttgtt catctaaaag aatttacaaa taaaatacat
    85261 gaaaagatgc aaaatgcggc aggatttgta atttcttctg attatgaagg tatatctaat
    85321 tctatgttag aagcactggc tattggagtg ccagttatcg ctacagattg tccagtaggt
    85381 ggcgcaagaa tgtatttagg tgatagaaat gaaataggtc atcttgttga atgtaataat
    85441 ctagataagt taacagatgc aatgcgtagg gtacttttgg atagagaaag tgtggtaaga
    85501 aaagcgcaaa aaggaattaa actaagaaaa gaactgacat ctaaaaatat ttcaaatata
    85561 tggtacgaat atttaaacca gttcttttaa ccaaaaggag gatattgtgt gaaagaaaaa
    85621 ataaatatat tgatgttttc gttaacgtta gtcgcgttta caatattttg cgctttttca
    85681 ttaaatcaga actattggct aaattggctt ggaatattga tttacttata tgcaatctgt
    85741 acatggcatt ggagaaaagg agattcaata ttttcattat acacgatttt tttcactctt
    85801 tttttattat ttagttatgg gcaatgcatt atgtgggcat tcggtattgg aacagatcgt
    85861 ggaatcggta caacagtagt agcttatggt acggggatta ttcctagtga atcagatatg
    85921 ataatggtaa aatggtattc ttgtatttct atgtttgtat ttcacatagg agcactctta
    85981 tttacgagaa aaaccacact aagaaaagtt agttggtatg aatctggaga tgctgatgcc
    86041 gatagaaagt ttttatttaa aatagggtgt atcatttcta taatagtagt accgatagtt
    86101 tttgtttcta aattactaga ggtacgtata gcattagtcc atggttataa tgcattatat
    86161 tatggtgatt atgctacaca aagtggatat ttacaaatta ttctatatct tttttttcca
    86221 gccttaatat gtttattaat tggtagcaac ttttcaaaag taataacgag atttgttttt
    86281 attatttttg ctttatattc tttattagga attatgtcag gagacagagg aagttggttg
    86341 tatagctcta ttatactcat atgggcatac actcaatata aaggaacctt taattataaa
    86401 aaattaataa agtggcttat tttagctgtt ataggaatat atattctaaa cgtaataacg
    86461 aaagcacgtg atggtggagg actaagtaaa cttactttaa aagattttac atctgtattt
    86521 gattcagatg attctccttt agttgattct ttttttgaaa tgggggggac tatgagtatt
    86581 ataacttttt tcctaataag tggtaatgga atatatccct ttgctaatac ttatttgacc
    86641 tcactcttag gctctatatc aacaagaatg ctatcaatgt ttggaataaa gtttgtttta
    86701 ttagctgatt ggttttctca ggattattta ggaatcactt gggggactgg attctcaatg
    86761 attgcagaag cctatgtcaa tggtggatac attgggggta tagtctatat ttttattatt
    86821 ggtatagtca tcggtaaaat cctttctaat agtatagaca accaagatat tgaaaatcat
    86881 cctatgaaga tgtttttggc tataactaca gcaaatatta taatgggttt tcctagagct
    86941 gcttcatatt taattgtgaa aaattttgtg tatggtgttt taattatatt gttgataaac
    87001 tttttcctac agcaatttaa taaacgtctt taatatttaa gcttaataaa aagataaaac
    87061 aagtcaggag ttgcaaaaat ggaaagaact gctcggctca aaaaaaacac tatttgggct
    87121 ctggtgtttc aaataacttc tattgtctgt ggtatgatct tgctacgttt gatattaaca
    87181 aagtacggat ccgaggttaa tggaatgatt agctctatta accaatttct acaaattatt
    87241 tcttttttac aattaggagt aggcgctgta atgcaatcaa ctctatacaa accactagca
    87301 gaaaaggata atttaatgat aagtcaaatc ttagcttctg gagggaagtt ttatcggcaa
    87361 attgcatata ttctactagt atacgtgggt ttgttacttg cagtctatta tgttctcgtt
    87421 cctaatgaat ttgggagatc atatacaatg gcaatgattg caacattaag tattaattca
    87481 tttgctcaat attattttgg tattgttaat actttgttat taagtgctga ccagaaaatt
    87541 tatattacgt atattgcaca gacaatagca tttatttcta atacagttgc atgtgcttta
    87601 ttaattagtc tgaacacaga gatccttatg gtaaaactta ttactgctat aatttatctt
    87661 gcttgtccaa tatattatag atggtatgtg gatcgaaact ataatataaa gaggaatgtg
    87721 tcatatgata aggaaccgat ccctcaaaaa tggaatgggg ttgcacaaca cgtagcttct
    87781 gttgtactag atagtactga tgttgtagtg ttatctatat tttctaacct gatatatgta
    87841 tctatatata atgtgtacaa tttagtaata tacggagtaa aacagctatt catggctatg
    87901 acaaatggcg ttcaggcctt actaggggaa ctttgggcca gaaaagaaat agaagttctt
    87961 tacaaaacat ttgcatggtt cgaatggatt gtacatactt tgacagtttt tatttttggc
    88021 tgtaccggta tactaatcgt tccatttatt caagtatata caagaggagt aacagatgct
    88081 aattataatc aattatcatt cgcagcttta cttgtaactg ctaacgcact tcactgtctg
    88141 cgtacacctt atcatgtaat gataaaagca gctggtaaat ataaagaaac tcaaaatagt
    88201 tttataattg cttctttgtt aaatttaggt ttatcattaa ttttggttaa accactaggg
    88261 ctagttggag tagcattagg atctctaatt tcaatcacat atcatacact ttggagtgca
    88321 aattataatt caaaatattt gcttaaatgg ccgatgaaaa aattctataa acagttattt
    88381 gtaaacatct taactgtagt tctttctttt ggggcgacat cacaattgaa aatgatgtca
    88441 atcacatatt tggattggat tgttctcgca attaaatgtg cagttattgt atttatatgt
    88501 ataatcctag ttaatgtttt attttataga agatatgtag taaaaataat tagtaaaatc
    88561 atcgtaaaaa taaagaaaat ttaatacaca ataaatgttt taataaactt aataaaatta
    88621 tatttgccaa aattagacac atatattaaa tt
//
LOCUS       DAXLPQ010000006        88528 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.006, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000006 DAXLPQ010000000
VERSION     DAXLPQ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 88528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.006"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            79..831
                     /locus_tag="ACF3UO_000534"
     CDS             79..831
                     /locus_tag="ACF3UO_000534"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3656586.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(853..2007)
                     /locus_tag="ACF3UO_000535"
     CDS             complement(853..2007)
                     /locus_tag="ACF3UO_000535"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFD3656587.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            2192..4633
                     /locus_tag="ACF3UO_000536"
     CDS             2192..4633
                     /locus_tag="ACF3UO_000536"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFD3656588.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(4963..5667)
                     /locus_tag="ACF3UO_000537"
     CDS             complement(4963..5667)
                     /locus_tag="ACF3UO_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656589.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(5854..6099)
                     /locus_tag="ACF3UO_000538"
     CDS             complement(5854..6099)
                     /locus_tag="ACF3UO_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656590.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(6116..6967)
                     /locus_tag="ACF3UO_000539"
     CDS             complement(6116..6967)
                     /locus_tag="ACF3UO_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3656591.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            7133..8137
                     /locus_tag="ACF3UO_000540"
     CDS             7133..8137
                     /locus_tag="ACF3UO_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFD3656592.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(8378..8734)
                     /locus_tag="ACF3UO_000541"
     CDS             complement(8378..8734)
                     /locus_tag="ACF3UO_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3656593.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            9102..10289
                     /gene="tuf"
                     /locus_tag="ACF3UO_000542"
     CDS             9102..10289
                     /gene="tuf"
                     /locus_tag="ACF3UO_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFD3656594.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(10477..13068)
                     /gene="mprF"
                     /locus_tag="ACF3UO_000543"
     CDS             complement(10477..13068)
                     /gene="mprF"
                     /locus_tag="ACF3UO_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFD3656595.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(13094..13855)
                     /locus_tag="ACF3UO_000544"
     CDS             complement(13094..13855)
                     /locus_tag="ACF3UO_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3656596.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            14022..14654
                     /locus_tag="ACF3UO_000545"
     CDS             14022..14654
                     /locus_tag="ACF3UO_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFD3656597.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            14713..15573
                     /locus_tag="ACF3UO_000546"
     CDS             14713..15573
                     /locus_tag="ACF3UO_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFD3656598.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            15758..18073
                     /locus_tag="ACF3UO_000547"
     CDS             15758..18073
                     /locus_tag="ACF3UO_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3656599.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            18255..20096
                     /gene="dnaG"
                     /locus_tag="ACF3UO_000548"
     CDS             18255..20096
                     /gene="dnaG"
                     /locus_tag="ACF3UO_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFD3656600.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            20120..21229
                     /gene="rpoD"
                     /locus_tag="ACF3UO_000549"
     CDS             20120..21229
                     /gene="rpoD"
                     /locus_tag="ACF3UO_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFD3656601.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            21446..23587
                     /locus_tag="ACF3UO_000550"
     CDS             21446..23587
                     /locus_tag="ACF3UO_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFD3656602.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            23783..24646
                     /locus_tag="ACF3UO_000551"
     CDS             23783..24646
                     /locus_tag="ACF3UO_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFD3656603.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            24751..25224
                     /locus_tag="ACF3UO_000552"
     CDS             24751..25224
                     /locus_tag="ACF3UO_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3656604.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            25320..26207
                     /gene="xerD"
                     /locus_tag="ACF3UO_000553"
     CDS             25320..26207
                     /gene="xerD"
                     /locus_tag="ACF3UO_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFD3656605.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            26226..26597
                     /locus_tag="ACF3UO_000554"
     CDS             26226..26597
                     /locus_tag="ACF3UO_000554"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3656606.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            26594..27364
                     /locus_tag="ACF3UO_000555"
     CDS             26594..27364
                     /locus_tag="ACF3UO_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFD3656607.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            27348..27917
                     /gene="scpB"
                     /locus_tag="ACF3UO_000556"
     CDS             27348..27917
                     /gene="scpB"
                     /locus_tag="ACF3UO_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFD3656608.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            27923..28639
                     /locus_tag="ACF3UO_000557"
     CDS             27923..28639
                     /locus_tag="ACF3UO_000557"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD3656609.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      28721..28845
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            28968..29579
                     /locus_tag="ACF3UO_000558"
     CDS             28968..29579
                     /locus_tag="ACF3UO_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3656610.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            29957..31480
                     /locus_tag="ACF3UO_000559"
     CDS             29957..31480
                     /locus_tag="ACF3UO_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD3656611.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            31717..33057
                     /locus_tag="ACF3UO_000560"
     CDS             31717..33057
                     /locus_tag="ACF3UO_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3656612.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            33211..33948
                     /locus_tag="ACF3UO_000561"
     CDS             33211..33948
                     /locus_tag="ACF3UO_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3656613.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(34113..34334)
                     /locus_tag="ACF3UO_000562"
     CDS             complement(34113..34334)
                     /locus_tag="ACF3UO_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFD3656614.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            34365..35396
                     /locus_tag="ACF3UO_000563"
     CDS             34365..35396
                     /locus_tag="ACF3UO_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656615.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            35383..36786
                     /locus_tag="ACF3UO_000564"
     CDS             35383..36786
                     /locus_tag="ACF3UO_000564"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFD3656616.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            36852..37487
                     /locus_tag="ACF3UO_000565"
     CDS             36852..37487
                     /locus_tag="ACF3UO_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFD3656617.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            37536..38216
                     /gene="cmk"
                     /locus_tag="ACF3UO_000566"
     CDS             37536..38216
                     /gene="cmk"
                     /locus_tag="ACF3UO_000566"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFD3656618.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            38351..39580
                     /gene="rpsA"
                     /locus_tag="ACF3UO_000567"
     CDS             38351..39580
                     /gene="rpsA"
                     /locus_tag="ACF3UO_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFD3656619.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            39762..41072
                     /gene="der"
                     /locus_tag="ACF3UO_000568"
     CDS             39762..41072
                     /gene="der"
                     /locus_tag="ACF3UO_000568"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFD3656620.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            41315..41590
                     /locus_tag="ACF3UO_000569"
     CDS             41315..41590
                     /locus_tag="ACF3UO_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFD3656621.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            41825..42871
                     /locus_tag="ACF3UO_000570"
     CDS             41825..42871
                     /locus_tag="ACF3UO_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656622.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            42873..44132
                     /locus_tag="ACF3UO_000571"
     CDS             42873..44132
                     /locus_tag="ACF3UO_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFD3656623.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            44138..44719
                     /locus_tag="ACF3UO_000572"
     CDS             44138..44719
                     /locus_tag="ACF3UO_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFD3656624.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(44801..45676)
                     /locus_tag="ACF3UO_000573"
     CDS             complement(44801..45676)
                     /locus_tag="ACF3UO_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3656625.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            45824..46156
                     /locus_tag="ACF3UO_000574"
     CDS             45824..46156
                     /locus_tag="ACF3UO_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFD3656626.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            46268..47476
                     /locus_tag="ACF3UO_000575"
     CDS             46268..47476
                     /locus_tag="ACF3UO_000575"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFD3656627.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            47630..48085
                     /locus_tag="ACF3UO_000576"
     CDS             47630..48085
                     /locus_tag="ACF3UO_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656628.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            48447..48722
                     /locus_tag="ACF3UO_000577"
     CDS             48447..48722
                     /locus_tag="ACF3UO_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656629.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            48735..50813
                     /locus_tag="ACF3UO_000578"
     CDS             48735..50813
                     /locus_tag="ACF3UO_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFD3656630.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            50976..52859
                     /locus_tag="ACF3UO_000579"
     CDS             50976..52859
                     /locus_tag="ACF3UO_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3656631.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            52871..53818
                     /locus_tag="ACF3UO_000580"
     CDS             52871..53818
                     /locus_tag="ACF3UO_000580"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFD3656632.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            53838..54365
                     /locus_tag="ACF3UO_000581"
     CDS             53838..54365
                     /locus_tag="ACF3UO_000581"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFD3656633.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(54428..55081)
                     /locus_tag="ACF3UO_000582"
     CDS             complement(54428..55081)
                     /locus_tag="ACF3UO_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFD3656634.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            55213..56055
                     /locus_tag="ACF3UO_000583"
     CDS             55213..56055
                     /locus_tag="ACF3UO_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3656635.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            56213..57109
                     /locus_tag="ACF3UO_000584"
     CDS             56213..57109
                     /locus_tag="ACF3UO_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3656636.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            57112..57825
                     /locus_tag="ACF3UO_000585"
     CDS             57112..57825
                     /locus_tag="ACF3UO_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFD3656637.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            57845..58363
                     /gene="msrA"
                     /locus_tag="ACF3UO_000586"
     CDS             57845..58363
                     /gene="msrA"
                     /locus_tag="ACF3UO_000586"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFD3656638.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            58360..58587
                     /locus_tag="ACF3UO_000587"
     CDS             58360..58587
                     /locus_tag="ACF3UO_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFD3656639.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            58739..59290
                     /gene="lepB"
                     /locus_tag="ACF3UO_000588"
     CDS             58739..59290
                     /gene="lepB"
                     /locus_tag="ACF3UO_000588"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3656640.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(59373..59915)
                     /locus_tag="ACF3UO_000589"
     CDS             complement(59373..59915)
                     /locus_tag="ACF3UO_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFD3656641.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(60152..60550)
                     /locus_tag="ACF3UO_000590"
     CDS             complement(60152..60550)
                     /locus_tag="ACF3UO_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3656642.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            60822..61781
                     /locus_tag="ACF3UO_000591"
     CDS             60822..61781
                     /locus_tag="ACF3UO_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3656643.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
     gene            61875..62735
                     /gene="ylqF"
                     /locus_tag="ACF3UO_000592"
     CDS             61875..62735
                     /gene="ylqF"
                     /locus_tag="ACF3UO_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFD3656644.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            62728..63495
                     /locus_tag="ACF3UO_000593"
     CDS             62728..63495
                     /locus_tag="ACF3UO_000593"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFD3656645.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            63551..64408
                     /gene="dprA"
                     /locus_tag="ACF3UO_000594"
     CDS             63551..64408
                     /gene="dprA"
                     /locus_tag="ACF3UO_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFD3656646.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            64530..66608
                     /gene="topA"
                     /locus_tag="ACF3UO_000595"
     CDS             64530..66608
                     /gene="topA"
                     /locus_tag="ACF3UO_000595"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFD3656647.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            66577..67953
                     /gene="trmFO"
                     /locus_tag="ACF3UO_000596"
     CDS             66577..67953
                     /gene="trmFO"
                     /locus_tag="ACF3UO_000596"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFD3656648.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            68151..69056
                     /gene="xerC"
                     /locus_tag="ACF3UO_000597"
     CDS             68151..69056
                     /gene="xerC"
                     /locus_tag="ACF3UO_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFD3656649.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            69093..69641
                     /gene="hslV"
                     /locus_tag="ACF3UO_000598"
     CDS             69093..69641
                     /gene="hslV"
                     /locus_tag="ACF3UO_000598"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFD3656650.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            69655..71055
                     /gene="hslU"
                     /locus_tag="ACF3UO_000599"
     CDS             69655..71055
                     /gene="hslU"
                     /locus_tag="ACF3UO_000599"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFD3656651.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            71073..71864
                     /gene="codY"
                     /locus_tag="ACF3UO_000600"
     CDS             71073..71864
                     /gene="codY"
                     /locus_tag="ACF3UO_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFD3656652.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            71946..72821
                     /locus_tag="ACF3UO_000601"
     CDS             71946..72821
                     /locus_tag="ACF3UO_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFD3656653.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(72953..73591)
                     /gene="plsY"
                     /locus_tag="ACF3UO_000602"
     CDS             complement(72953..73591)
                     /gene="plsY"
                     /locus_tag="ACF3UO_000602"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFD3656654.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            73718..74152
                     /locus_tag="ACF3UO_000603"
     CDS             73718..74152
                     /locus_tag="ACF3UO_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFD3656655.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            74318..76363
                     /gene="parE"
                     /locus_tag="ACF3UO_000604"
     CDS             74318..76363
                     /gene="parE"
                     /locus_tag="ACF3UO_000604"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFD3656656.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            76375..78825
                     /gene="parC"
                     /locus_tag="ACF3UO_000605"
     CDS             76375..78825
                     /gene="parC"
                     /locus_tag="ACF3UO_000605"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFD3656657.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            79102..81333
                     /gene="pflB"
                     /locus_tag="ACF3UO_000606"
     CDS             79102..81333
                     /gene="pflB"
                     /locus_tag="ACF3UO_000606"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFD3656658.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            81577..82338
                     /gene="pflA"
                     /locus_tag="ACF3UO_000607"
     CDS             81577..82338
                     /gene="pflA"
                     /locus_tag="ACF3UO_000607"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFD3656659.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            82423..83349
                     /locus_tag="ACF3UO_000608"
     CDS             82423..83349
                     /locus_tag="ACF3UO_000608"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFD3656660.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            83531..84424
                     /locus_tag="ACF3UO_000609"
     CDS             83531..84424
                     /locus_tag="ACF3UO_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFD3656661.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            84558..84683
                     /locus_tag="ACF3UO_000610"
     CDS             84558..84683
                     /locus_tag="ACF3UO_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFD3656662.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(84817..85449)
                     /locus_tag="ACF3UO_000611"
     CDS             complement(84817..85449)
                     /locus_tag="ACF3UO_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656663.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(85597..86139)
                     /locus_tag="ACF3UO_000612"
     CDS             complement(85597..86139)
                     /locus_tag="ACF3UO_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFD3656664.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            86274..86663
                     /locus_tag="ACF3UO_000613"
     CDS             86274..86663
                     /locus_tag="ACF3UO_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656665.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            86667..87431
                     /locus_tag="ACF3UO_000614"
     CDS             86667..87431
                     /locus_tag="ACF3UO_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3656666.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            87560..88507
                     /locus_tag="ACF3UO_000615"
     CDS             87560..88507
                     /locus_tag="ACF3UO_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3656667.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
BASE COUNT        30262 a        15226 c        18565 g        24475 t
ORIGIN      
        1 agagatagaa tagataaaag aggagaataa tttattccga aaagtgaaaa catataacaa
       61 aaaattagag gaaatcaaat gaatgaaaaa gaatgggatg aatttgctga agaatattat
      121 gaaatccagc aagaatcgca agtaactatt gctgaagatg taaaaaatta tctgaaaacg
      181 gagaaagtcc tgcctgctga aacagcagca gacgttgctg gaggatctgg cagatttctt
      241 tccttagcaa aagaaattaa tcgctatgat ttgatcgatt tttcttcagg aatgctagaa
      301 aatgcaaaaa aagaagcaga aaaaaatgag ttgccaaatg tttcctttat caaacagtcg
      361 ttagaagaat ttatccaatc aaatgagaca tatgaaatgg tttttacagc agcaaatcca
      421 gcattggtac atcttattca attagaaaaa ttgatgaaaa agtcaagcaa atggtgcgtg
      481 ataatcaggg tagtggaatc aatcgatgat gttttttatc ctatcgaaaa gcaactagga
      541 atgatagaag aagatcctaa tacatcgcca gttgtaatgg atcaatttga aacatactta
      601 attgatgaag gattcaaagt gaagaaaaaa gattttactt attttacaca ggaatcaatt
      661 actgaagaat tgatgaagct atactatgac gcgtacgcaa aagatcctgt tgtgaccagg
      721 tacattcgca aactattcag tgaaaaacga gaaatcctta gtacgactaa gctgacctat
      781 agactgctcc tttggtccgc agataaaaaa agaacctttc acgactcgtg aagggttctt
      841 tttatgattt tattatattt tgtagtaacg aatatcattt tcgatctttg taatcgaaaa
      901 aggtacatct gaagtatatt ctgcacattc tccgtgttca ggaagcgtct cactgaaaat
      961 cgtttcatat tcgtcaacag tgatccgtgt tcgagaatct agcatctctt gatgagattg
     1021 tgcgaagaga tattcttgat agttttcttc cagataacct gtaaaaaatt cacttactgc
     1081 accagaaccg tagctgaata gaccgatgcg atctcctggc tgtagtgatt tcgaattttc
     1141 cagtagagaa gttagcccca ggtataatga accagtgtaa agattaccga ttcgtcggct
     1201 gtaacggatg ctttcttcat agcgagccat aagacgttcc tgattttctt cgtctgtttg
     1261 gtctaatacg ctttgcaatg ccttttttcc catcttagta tacggaatat ggaaagcaat
     1321 cgcctgataa tcttcgagtc ctcgacccga caattcttta tgtcgattcc aaactttttg
     1381 gaatgattcg atatacgtag aattagataa aggaccatca acaacaggaa attcgctata
     1441 atctggacgc cagaaatcat agatatcttc tgtcagaaat acgctgtcgt cttcaatcga
     1501 taaaatacgc gggttttgag tgatcatcat cgcaacagca ccgacacctt gcgtcacttc
     1561 accaccgctt gccaagccgt aacgagcaat atcacttgct atgactagta cttttcgttc
     1621 tggatgattt ttgacatatt ctttcgccat gtgcaaagct gcggtgccac cgtagcaagc
     1681 ctcttttact tcaaaagaac gagcaaaaga ttggattttc agtaaatggt ggataattac
     1741 cgcactcgct tttgaatgat caatcccgga ttctgttccg acgatgacca tgtcgattag
     1801 ctcacggtct ttttctgtta cgattttgct ggcagcattt gctcctagtg taatgatgtc
     1861 ttcatttgca cgattgactg ccatttggtc ttgaccaatc cctatatggt attttgcagg
     1921 atcatcccca cggctttctg ccaactctgt catatctaaa tataaattag gaataaaaaa
     1981 ggaaagacga tcaatcccta ttttcatttc aacacctctt tacttatgat aaaaaactta
     2041 ctttactaag gtatcataaa aagattaaaa gaaatataaa aaagagaata tttaaggatt
     2101 gttaaaattt aatcttagaa aaaaacaact ggaacaagag ctatttgttt ttacagcaaa
     2161 gaatggtata tttttgtagg aggtggctta cttgaaagaa gtcgttatga tagatgctgc
     2221 aagaacgccg ataggaaagt atcgcggaag tttaagtcca tttactgcag ttgaattagg
     2281 cacacttgtg actaaaggat tattagataa aacaaaactg aaaaaagata aaatcgatca
     2341 agtaatattc ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca gacagattgc
     2401 tttgaacagc ggtctccctg tagatgtccc agcaatgacg atcaatgaag tttgcggatc
     2461 tggtatgaaa gcagtgatct tagcacgcca gctgatccaa ttaggtgaag cagaacttgt
     2521 gatagccggc ggaacagaga gtatgtctca agcacctatg ctgaaaccgt atcagtcaga
     2581 aacaaatgaa tatggtgaac caatttccag tatggtcaac gacggattga ctgacgcatt
     2641 ttcaaatgca catatgggat taaccgcaga gaaggttgca acacaatttt ctgtgagcag
     2701 agaagaacag gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg ctgtcgaagc
     2761 cggtgtattt tctgaggaga tcatcccagt caagatttct gatgaagacg tgttatctga
     2821 ggatgaagca gttcgtggaa atagtacatt ggaaaaactg ggcacgttac gtacagtatt
     2881 ctcagaagaa ggaactgtaa cagcaggaaa tgcttcgcca ttgaatgacg gtgcctctgt
     2941 ggtgatcctt gcatccaaag aatacgcaga aaataataat ctgccttatt tagcaaccat
     3001 caaagaagta gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc caatcaaagc
     3061 cattcaaaaa ttgacagata gatcaggaat gaatttatca acaatcgatc tttttgagat
     3121 caatgaagca tttgcagctt cttctatcgt agttagccaa gaactgcagt tagatgaaga
     3181 aaaggtcaat atatatggag gagcaatcgc attaggccat ccaattggtg caagcggtgc
     3241 acgtatcttg actacattag cttacggatt gcttcgtgaa cagaagagat acggtattgc
     3301 ttcattatgt attggtggag gtttaggctt ggcagtcttg ttagaagcga atatggagca
     3361 aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg aacggcgcag
     3421 tcaattaata gaaaaaaatg tattgacaca agaaactgcg ttgatttttc aggaacaaac
     3481 actttctgaa gagctctccg atcacatgat cgaaaaccaa gtgagtgaag tggaaatccc
     3541 aatgggcatc gcgcagaatt ttcaaatcaa tggtaagaaa aaatggattc cgatggcaac
     3601 agaggaacca tctgtcattg cagctgcaag taatggtgca aaaatctgtg gaaatatctg
     3661 cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa aatcggagta
     3721 tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag ctgattcttt gtgcaaatga
     3781 aagttatcct tcaatcgtga aacgcggggg cggtgttcaa gatatctcta ctcgggaatt
     3841 catggggagt ttccatgcat acttatctat tgatttttta gtggatgtaa aagatgcaat
     3901 gggcgctaac atgatcaact cgattcttga gagtgtggca aacaagttac gggagtggtt
     3961 ccctgaagaa gagattctat tcagtatttt aagtaatttt gctacagaat cattggcttc
     4021 tgcctgttgc gaaatcccat tcgaacgctt agggagaaac aaagaaatcg gtgaacaaat
     4081 tgccaaaaaa atccaacagg caggggaata tgcgaagctt gacccttacc gtgcagcaac
     4141 gcacaacaaa gggatcatga atggtataga agctgtagtg gcagctacag gaaatgatac
     4201 acgtgcggtt agcgcttcga ttcacgccta cgcggcaaga aatggattat accaaggatt
     4261 aacagactgg cagatcaaag gggataaact agttggaaaa ctaacggtgc ctttggctgt
     4321 tgccacagta ggcggagctt ccaatatcct gccaaaagca aaagcatctt tagctatgtt
     4381 agatattgat tcagccaagg aactagcaca agtaattgct gcagtagggt tagctcaaaa
     4441 cctggctgct ttgcgtgcat tagttacaga aggaatccaa aaaggccaca tgggacttca
     4501 agctcgttca ttagcgatct caattggggc tattggtgag gaaatcgagc aagttgcgaa
     4561 aaaattacgt gaagcagaaa agatgaacca gcagacagct atacaaatat tggaaaaaat
     4621 ccgggaaaaa taaaaaagca atatctttag aagaataaag caagatttac agttatttta
     4681 tttactgcaa atcttgcttt tttctctatc agaaaatatg tttattatta gaatttttta
     4741 tagttaaggt taggcatctt aagaaatcag gcaactccaa gatatcttca ggtagaagag
     4801 aagtcgccta acattgtagg atcataggtg atttgttgga caggtcaagc tgatatttga
     4861 gcctgatgtt agaaggaatt tctttttact tgctgtagaa attattatat gactaaaaag
     4921 gctgggattt taaatcccag ccttttatga caaatagaat ttttatcgat cagtaatcgc
     4981 tgtcgctgca aattgttcga tcaaaggaat caaagtcaat ttgactttgt atttccgttc
     5041 gagtgctttt tcgataacga actcattttc agtagtcata gaaatagttg ctaatttacg
     5101 aggttcatca gcattttttt cattaataac tacttcatgt tcattttgtt ctgtgtaaaa
     5161 tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa cttaaagcgg cattcgtatc
     5221 agttgagcgt gtattttcag ttgtgtccgc ttttggtttt tccgtttttt cttctggcac
     5281 actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc gcagttggtt catcgttttt
     5341 caatcgttga tcattccagt aagacacgat ttcaataaga agattgtcac ggaatcgttc
     5401 gaaaatcccg ttttctcctg aacgaattct ctttaataca gtattgaagt tgtcatcgat
     5461 tggcacgttg atccgtgtat cttcatttgt tttcccagct aatccgatcg ttaagatttg
     5521 acggtttttg ggatcaagca tgacttgtaa cggcaaacca tagcgtcgca agctctcttc
     5581 ttctagagaa cggaataatt gtcctcttac accatccaat gaaggacgga attgatttaa
     5641 taatttttgt ttctgttttt tcttcatatg ttctctcctt cgctcatacc ctttcgatta
     5701 taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa aacttgcgta tacgcaaatt
     5761 acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga aaaataaaaa atggaacgga
     5821 ttatgtatat atacataatc cgttccattc tttctatttt ttcggtatca aggcaaaaac
     5881 aggtagttca ggtgaataaa tgacttcatg ttcgtgccag ggtttgacca ttagcgaatg
     5941 atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt gtccagtttc ttgcaggaaa
     6001 atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg gaatgaaaag tctgggtaac
     6061 ttcttccgag agagaattca agcgttcgat tggatccata aaatcacctt tcgacttaaa
     6121 attgggtagt atctgggtct tttgctttgc cgactacacc atctaactga tcgatttgtt
     6181 tcatttcttc ttctgttaat tcaaaatcaa ataattcagt attttctttg attctgcttg
     6241 gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag cgaccaacgc aaagcaactt
     6301 gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat ttcaggcaca tcgaagattt
     6361 taccagtgcc taatggacta tatgcttcga ggatcatatc atgttttttt gcatactcaa
     6421 ctacagttgg ctgtaattcg cctggtgcaa ggaaaacttg attgaccatc ggcataattt
     6481 ttgctgtttt tgctagtgta tctagatggt ggggtaagaa attgctcaca ccgattgctt
     6541 tgattttacc tgcttcatac agttcttcaa atgctcgcca tgtatctgca tttgcttgtt
     6601 cccaattatc acgaaaagca acagggtttg gccagtggat caaaaacaga tctaaataat
     6661 ctgtttggag cttcttcaat gattcttcaa aagaagacat cacaagttca tagctgtggt
     6721 ttgcattcca taattttgtt gtcaagaata tctcttctct aggaattcca ctttccttaa
     6781 tcgcttggcc gacactttct tcattcttgt atccttgggc agtatcgata tggcgataac
     6841 ctgcagccag cgcttcttta acagaggaaa cagcgacatc cccatcaggt gtttgccatg
     6901 tgccgaatcc tactaccggg atttcgtaac catttaatag acgataagtg cttgttaatg
     6961 aattcatact ttcagctcct tttttattcg ttcaactata agtgtagcgc atttttcgaa
     7021 aaaaagaatc cattttgttt ctactcttga aatttttgtt taaaagaaaa tgattttgat
     7081 tctggtattt ttgatttttt ttccgtaaac taagacagaa gggaatgaga aaatggatat
     7141 ctatttaaaa aaagcaattc tgcatattat tgacagagaa actggttctc cagtcttttc
     7201 acaaaaagag ctggatctga caaaagaata tattcgtgat tttcttcaaa agaagatcca
     7261 aaaaatctct tctgctcaaa caaaaactgg acaactagca gaagaaagca tgatcgttga
     7321 atcacttaaa atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg ttcagcggtg
     7381 gttcgatatc taccaagaaa gtgaagaagc acctagtgca gatgtatttg ttgttttgta
     7441 tgaattagat acagtgatgt acttatcttt attgaaagtc aattatcgtg aggcttacac
     7501 tcactttgtt gaagcagacg aagcagggat cgacaaccgc ttgattttga atcgagcaat
     7561 tctaggggcg aaaacacaaa aagcagatga agcattcgct gtgaatttga ctgattggac
     7621 ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt atttttctgg
     7681 aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag tgatccaaaa
     7741 agtagccaag catcttggaa aaaaatttga gacagaagaa tttgatatca tggctgattt
     7801 gaaagaagct gtctatgata cgatagaaga aaaaggtcgg ttggatcatg agatgattgc
     7861 ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct tttaaagaag aagtacaaga
     7921 gcaaggattt gtcccagaag cacctcctgt aaaagaagta caagaaattt ctgagaaaaa
     7981 atttggaaaa caaaaattca agctatcaaa cgggatcgaa ctgatcgtac cagtagatgt
     8041 atatcgcaac ccagatttga ttgaatttgt gaataatccg gatggtacga tatccgtgat
     8101 gatcaaaaat gtggatgaag tattgaatcg tttataaaaa tgactagaac attaggtgtt
     8161 caagtaccag tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa agacgaatat
     8221 aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt
     8281 ataaacggcg gaagcagaag caactccttc ttatttcttg gagttaaacg cttctgtccc
     8341 agcctctttt tatctaataa aattttaaga ccatttacta attatcgatt ttttctgccg
     8401 catttttagg cacttcagaa gcctttattt cttcccagct taatacacct ttacgaggat
     8461 tgactttgag tttaagatac gcattcatct ttaatggatg ttctctttct tcgcgaagcg
     8521 tcacctgttt tttttcacca tctttattat aagccgcttg cttgtaggta taagtcgtga
     8581 atttctctcc gttatctgct tgggtagctg acatttcgcc attcgtcgtg atttttgtat
     8641 aataagcttc gccgccgtaa aaataatgat aagctgcaaa acttccgccg agaaatatgc
     8701 ctaaaacgac aagtacgcca attaattttt tcatgtactt cacctctttc cttattatta
     8761 acgaaataga agatttcgtc tattgaaagt tgttggcaac agctgaattt taaacttttc
     8821 ctcattttgt tcttattgct tcaaaagaaa gttaaggact atcttgaagt ttttctcaaa
     8881 aaacacattt ttttatttat aaaaggtact tttttcgcgt ataagacaag cgagtgctct
     8941 tagttgactt tgaccaatat tgacgtataa taagcttagt tcgaatctta caaaaagtaa
     9001 gtcggacgta ttctttttga tttagtcaaa aaaagactat aataaaaagg tgagagctga
     9061 aatttttcag tgatctatat tatttaggag gtttgtaaat tatggcaaaa gaacattatg
     9121 acagaagtaa accacacgtt aacattggta cgattggaca cgttgaccat gggaaaacta
     9181 ctttaactgc tgcgatcact acagtattag gcaaaaaagg cctagcaaat cctcaagact
     9241 atgctagtat tgatgcagct ccagaagaac gtgaacgtgg gattacgatc aataccgcac
     9301 acgtagaata tgaaacagaa aaacgccact acgcgcatat tgatgcacca ggacacgcgg
     9361 actatgtgaa aaacatgatt acaggggcag cacaaatgga tggtgcaatc ttagttgttt
     9421 ctgcaactga cggtccgatg cctcaaacac gtgaacacat tttattgtca cgccaagttg
     9481 gtgtaaaata cctgattgtt ttcttgaaca aagttgattt agtcgatgat gaagaattga
     9541 tcgatttggt agaaatggaa gttcgcgagt tattgagcga atatggtttc ccaggcgatg
     9601 acactcctgt gatcaaaggt tccgcattaa aagcattgca aggcgatcca gatgctgaag
     9661 ctgctattat ggaattgatg gatacagtag atgaatatat cccaacacca gaacgtgata
     9721 cagataaacc attactattg ccagtggaag acgtcttctc aattacaggt cgaggaactg
     9781 ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg tgatgaggta gagatcgtag
     9841 ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt agaaatgttc cgtaaaacgt
     9901 tagattacgg ggaagctggg gataacgtag gcgtgttgtt acgggggatc caacgtgacg
     9961 atatcgaacg tggacaagtg cttgctaaac caggttccat tactccacat acaaaattca
    10021 aagcagaagt gtacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcaaca
    10081 actatcgtcc acaattctac ttccgcacaa ctgatgttac aggaacaatc acattgccag
    10141 aagatacaga aatggtcatg cctggtgaca acgtgacgat tgatgttgac ttgatccatc
    10201 caatcgctgt tgaaaacgga acgacattct caattcgtga aggcggacgg acagtgggtt
    10261 caggtatcgt tacagagatc gaagcataag aaacgcgact cgaatatttt ggtaatgaaa
    10321 aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt ttggaccgct ctttgttctt
    10381 caattgtata agaagagatt gtagaagcat gaactttcgt tttacttcag tctcttttat
    10441 tcatcatgag agtgttcatc tatcggtatg cagtttttaa tactttcttc gtatccattt
    10501 tttcaaacca cttattctac cttgtgtctg ctcaactggc gcattatcaa taatcagcaa
    10561 agcaatcata acatatgcaa tccaactatc tctagaatat agagtataac gtgagaccca
    10621 gtttgtagcg tacttgcttt tatattctct taatccatgg aaagaataaa aatgagaacc
    10681 aaactcgtaa accaagtatg caatcctttc ctgtaaaaaa ctctttctgg aagttccgac
    10741 atttgaaaga ggggccatcc ctaaattgaa ccattggata tgttcttctt tcatataggc
    10801 aaacaaatgc aagaacaaga aatccatact gccagaaggt gcttttttag gatcatatcg
    10861 catcagatca atcgttccta ctttattgtt cgtgtaagta ggcatgatcg ttgcaaaagc
    10921 gacaatttct tcttgggtat ttttgacaac tgcaataggc gctctttgta gataatcttc
    10981 agagaaaaag cctaaagaaa accctttttc ctttcgtgaa cccaaccaat tatcagagat
    11041 atttttgaaa gtactcattt gctcagtaga aaatggtggt tgtaagacat caaatgtaaa
    11101 tccttctcgt tcgatccgat tcaagacagc acgagtgccc ttcatttttt tccctgaagt
    11161 tgtaaaacta ttcaggtcta cataagcttc ttcccccatc ttaatgaaat cgtagccgaa
    11221 ttcatgcaaa atcataacaa tctcttcgct tgtttcgtag aaaactggta aatagcatag
    11281 tcgatctgtt tcttcgataa aagcttcgat tgcttctgga aaatcttctt tcttaccaga
    11341 aggatcaccc attacaatac atttattatt gaagcaagcg aattggagaa gaacagttgg
    11401 ttcaccgtct ttttcatagg caaacatccg cttatctttt aagaagatca attgactatc
    11461 ggagtttcct ccataagttg taaggatctt cagggccttt tcttcattaa aggcttcgcc
    11521 aatctgtttc ttttctcctt gaaggaaatg aacaaataga acgatcatga aactaacagc
    11581 gatgatggcc aacaatcccg aaaaccaaat cttttcagaa ggaaataaga aaaaggaaat
    11641 aaaatggtga cgccgatgag ggaaatccgg cagattgtat accccaataa cgatgtaaag
    11701 caaggacagt gcaccaataa tgattccatc gatcgtacgc cactcccatg aatagatcaa
    11761 ttgttcccga aataattcgt ttttagaagc aagaatgatc agaagcagaa tagacaagaa
    11821 aaccaccggt gtgaaactaa aatcacttaa taaaacataa agtaaagcta gaacaatcaa
    11881 gaagattgta ggcaaatatg ctcgtttcac acgtgctgcg atccctctgc ccataatgat
    11941 taaaagaaat cccaatagta tactaggaaa ttggataata aaatgaaatt tcaatgggtt
    12001 caaactatga agccagcgaa actctgtaaa agcttgcggg atagtggcag aaagtactag
    12061 catgattcca gaaaagtata ataagacaac cacgatttta tgcgcaattt ctgttgctaa
    12121 ttgtttaggg ataccagaat aacgctgatc aaaagtggaa ccgatatttt tgaagaaaaa
    12181 gacgattcca atcaaaaacg gaatgatgta gtagaacagg cgatagagca agatccacac
    12241 aacgactatt tctcttggca caccaatagc ggacaacccg ataatcatca ttacatcgaa
    12301 actcccaatt tctcctggaa tcatagacac gattcctatc actgaagcag caatgaataa
    12361 cggaattgtt tgccacagat caatccggat ttccattaaa taaccaacag aaaggaaact
    12421 aaacaggaca ccggtccatt ccaacaatga aactagcaat agctgtcctt gagttttaag
    12481 tgaggtacca ccaaggaatc ctttcttttt gaaagtagta aataaaaaga cgacaggaaa
    12541 atatagaccg ccgccgatca accatatcca atattgcttc aaaaaaggag caactggcgt
    12601 gaagactaca agtaaaaaag aaagcagact gtaaatagaa agtccagcca tcaaaaacaa
    12661 gaaaactttc gataatgctt ggatcacgtt tctgctctct ttcttttgtc catatagttc
    12721 agagcgaagc cccacactaa caaacccgcc gaaaccggca atattgttga ttgtattgat
    12781 cagccagctt gtctcaaaca agtaacgagg attctgcttt tgttcaagca tccgattcaa
    12841 aataatatca taaccaatca taggtaacac agagacaaga ccaatcaaca gcataagtcc
    12901 gcttttccat acaggtatag tggcaaacgt ttctcctaat tgctggatag atagagtttt
    12961 accgatggac atcaattcac cgacaataat gacaatgaca gaaatcaaaa agattgtttt
    13021 gaacagtcct aggtggtttt tcagccattg tatggtattt tttaacaaat aaatcacctt
    13081 ctattcctaa tagttatgtt tcagaaagaa attgaagaac ttctcgattg aagcgttcag
    13141 gatcttttct agctaattca tgtccttgtt ctttcacaag cacaaaggaa gcttttggta
    13201 tagttttagc tatatacaaa gaatgtttta gcttgattac atcttttttt cccacgatga
    13261 tcaaagtggg ggagttgatt ttttttaaat cattttctgt aagcccgatg tcatgcagca
    13321 aaagtttgat aactaaaaga tttttgcgaa gacttgggcg aaataaagag agtaaccata
    13381 cccatgcata atgaatatta ctgatgactc tggcagaaaa acgaacgcct ttaacaagcg
    13441 tgtttccaga atttaaaatc aatcgatgaa cttttttagg gaagctgctg gcaaatacca
    13501 gtgctagatt tgctccatca ctaaatccaa gaaaatctgc ctgatcgatt ttttccagca
    13561 acatgatcgt attcagatcc tcggccatta actgaaaatt caacatagat gcttcgtttg
    13621 tcgaacgacc atgtcctcgg ctatctacta gatacacggt atagtagcgt tcgagtacag
    13681 ggacctgttc tgaaaaaaag cggccgctgc cgtcattgcc atgcagtaaa aagagaggga
    13741 agccttgacc gctcttttca tagtaaattt cgctcccatc tggcattttt gcatatttct
    13801 tttctttttt cacataatca cctactgtgt aaagtataac gattatatca gtcattgggc
    13861 aattgttttt actgaaaaac aacgatcatt ttcgtaagat gacaaaaaat acaggaaaat
    13921 tcattttttc ttaaggcgta cacagaaatc aaggaagaaa tagccaagaa gataaagaaa
    13981 tagtaagata aaaaaagatg tcaaaataac taggtgatga aatgaagcga aaacgattat
    14041 ctattatccg tattcttttt tacatgatca ttctgacggt tattggtgcg gtgttgtttt
    14101 taggaggaag aacttatcgt tcggtaaaac gagtggaaag ctatcaaata gaaataacaa
    14161 cagctgcaaa aaattatcat atggaaaact acgagaattt gatcaaggcg ataatattga
    14221 ccgaatcaaa aggaaaaggg acagatctca tgcggagctc ggaaagtctg catggagaag
    14281 ctgagatcat tgataatcca gctgacagta ttgatcaagg tgtcaaatat ttggcggaaa
    14341 tgatagtaga agcaaagaaa caaggatgcg atttatggac agctgtccaa gcatataatt
    14401 ttgggaaaga ttatattgcc tatgtaaaaa atcatggcgg agaaaacaca gtagaattag
    14461 cagaagcgta ttctaaagat gtgctgagcc cacttttagg aaatgaggaa gggaaacaat
    14521 accgatattg gcggatccag tccttgcttt acaatggcgg ctatctctat cataatggag
    14581 gtaacatgtt ttatcctgat attgtcaaaa tgaatgaaaa aataatagag acctatgaaa
    14641 aagtttttaa gtaaaatagc aggaaatgtt caatcatgaa taaaattaaa tgaaagaagg
    14701 agtgcgcaaa tagtggaaaa aaggcaaaaa atggaaaatc aaaaagtggg gtacacaacc
    14761 aaagactgga tgttacggtt tgtgaaggga atgtttatcg gttcaggatt tatcttgcca
    14821 ggagtcagcg gtggtgcatt agcagctgtc tttggcatgt atgagcggct gatttctttt
    14881 ttagcccacc ttacaaaaaa tttcaaagaa aatgttttgt tttttctgcc tgttggtcta
    14941 ggcggagtga caggcatctt tctactttct tttttagtca gttttttatt aggtgcgtat
    15001 gaaacaacga tattatggtt ttttgtcgga tgtatcgctg gaactgttcc tgcgttatgg
    15061 aaagaagcag ggaaaaaagg aagagatact tctgatgtga tcatcatggt tgttactttt
    15121 gttctggctt atttgttttt attatacggc gctcaattat ttgacgggca agtcgatcag
    15181 aattttggaa catggctgat tgccggcgga ttgattggtt tgggtatgat cgtcccagga
    15241 ttgagccctt ctaatttttt ggtgtatatg ggattgtata aagcgatggc tgacggattt
    15301 aaagaagtac gacttgaagt gattgtgccg atcggaattg gtgggattct ttgtgttctt
    15361 ggattgtcaa aaatcatgga ttacattttc tcaaaggcat atagcaagct attccatttc
    15421 attttaggtg tagtttttgc ttcaacgatt atgatcattc ctaccgatta cgcgggattg
    15481 ggagttgctg gggtactagc ttgtcctgtt ctttttatag ccggtacagc actaggttgg
    15541 tggatgagcc gtttggagga acaatataag taaagataga ttgataataa aaacagcaca
    15601 cgggtgattc aaacaaaaag gttggcatct tttttgtaaa atcattcgtg tgtttttcta
    15661 taaattttat aaaaacaagt tgtttttaat cttggaacac gctagactta aacacgtgat
    15721 tatttttgaa agttggcgga aaatggagaa aaagaaaatg aatggactta cacagcaaga
    15781 ggtagttcag aaaatggctt ctggccagca aaatgactac caggaagatg catcaaaaag
    15841 tacaaaacaa atattcagcg ataatatatt gacgttattc aattttctga actttggtat
    15901 tgggatttgt ctgttatttg taggtgcgta ttccaacatg gcgtatttag caattattgt
    15961 cgtcaatatc gttattggaa tttatcaaga aatacatgca agaaatcttg tacggaaatt
    16021 atcgattgtt tcccaatcag aagtactagt gatccgggac ggtaaagaac aatcgatttc
    16081 tactaaagag ctggtattag gagatttggt aaaaatcgga gcaggagaac agataccagc
    16141 cgatttacag gttatatctg gacgggcaga agcaaatgaa gctcttttga caggcgaatc
    16201 tgatttgatt gtcaaagaaa ctggagctga attgctttct ggaagctttt tgacaagcgg
    16261 ttctgtcatg gctgaagtta tccgagtagg tgcagataat tatgctgtcc gcttgactag
    16321 cgaggcaaag actcacaaag ctattcgttc tgaacttgta gattcgattc gcaaagtatc
    16381 caaattcact agtttcgtga ttattccttt ggggatcata ctatttttgg aagcactgtt
    16441 catccgcgat gcttctatca aaatttctgt tattgcatct gcagcagctt tgttaggcat
    16501 gcttccaaag ggtttggtat tgctaataag tattgcatta acgacagggg taaccaaact
    16561 ggcaaaaaaa cgaatccttg ttcaagacat gtattcaatt gaaacgctgg cccatgtcga
    16621 tacattatgc ttggataaaa cagggaccat tactgaagga aaaatgagta tccagcgggt
    16681 agaagcacta catccgctgt acgagaaagc catcccagaa attatgggga cgtatctggc
    16741 agaaagcagt gataacaaca tcactatgcg ggctatgaga gattattttg agctttctaa
    16801 tcggtatgat gtgacaaaca aagtcgcatt ttcttctgat cgcaaatggg gcgcgatgga
    16861 atttccagaa ctgggagtcg tgtacgtagg agcgcctgaa cgtttggtgg aagaagatcg
    16921 gcttccggac agtctaaaaa cagcccaagc gaatggctat cgcgtactta tgttagggat
    16981 cgctccaaat cagcaattga acgaagaaaa accagcattt gttgagccgg ttgctctgtt
    17041 tgaaatcgat gatccaatcc gaaaaaacgc tcaagaaaca ctagcttatc ttcatgagga
    17101 aggtgtggat ctgaaagtga tttctggaga caatcctttt actgtctcca atatcgctag
    17161 acgtgcagga ttaccgaatt atgatgcgta tgtcgatctt tctcaaatta ctgaagaaat
    17221 ggaagtgcga gaagctgctc atcgctatac ggtttttgga cgagtgagtc ctcagcaaaa
    17281 gaaattgctg gtaaatgaat tgaaagaaag cggcagaacg gttgcaatga caggcgacgg
    17341 tgtgaatgat gttttggcgt taagagaagc agattgtagc attgctatgg cagaaggtga
    17401 tggagcaaca cgtcagattg cgaatctggt attgttggac tctgatttta ctacattgcc
    17461 agaagtcctg tttgaaggac gccgagtggt caacaatgtg acgaaagtct caggcatctt
    17521 ttttatcaaa acgatttatt catttatttt atcgattata tgtgccgtta cagcaattgg
    17581 atttccgttt atccctatcc aaatcacgct gattgattta gcgattgaag ggtatccttc
    17641 cttcttttta tcttttgaac aagataaaag aaaaatcact taccgttatt tgcctacagc
    17701 acttattaat gctttaccaa atgccttgct tgtagtagtg aatatcattg cggtgtatct
    17761 acttggaaaa acattcgcat ggggaaatgc tgaaactact actttgatgt attacttgct
    17821 gattgggatc agttgcatgg cagttgtaaa agcttgttat cccttcaacc cattgcgcat
    17881 cttcctagca gtaacgacga tcgtagggat atatgtagct gcaatgctgt tccatggaat
    17941 tttggaagta aacttagggt tgggagagag cgtaggatac ttctttgtat tcatgctcgt
    18001 aaatattgtt cttcgagtat tgtactggaa ggctgatatt caaaatcagt tactgaaaag
    18061 agtagcaaat tgatgcttaa tgagatagaa atgtgttata cttgaaaaag caatgaaata
    18121 tgatacaatc aaacatgtat aattgtgtcc tttaaaatcg cactgatttc agttagtgcg
    18181 attttttacc ggttattctc ctgaaatatc ttctgttaaa cccaaaagat atcaatagag
    18241 cagggggtgg aaaaatggct caacggattc ctcaagaggt tatcgaaaca gtacgcagtc
    18301 aaacgaatat cgttgaggtg attggacaat atgtccagtt gaaaaagtct ggtaaaaatt
    18361 acttggggct gtgtcctttt catgaagaac gtacaccgtc tttttctgtt gcagaagaca
    18421 agcagatttt tcattgcttt ggttgtggta agggcggaaa cgtgtttact tttcttcaag
    18481 aactagaagg tctaagtttt ccagaagcag tggtaaaagt ggcagacttc gaacagatac
    18541 cgttagaaga tcaatggcgt cagcgtacta tagctgtcca aaatcctgaa tctgctacgg
    18601 ggaaactgat tgctgctcat gaaaaagcag cggaaatcta tcatcacatg ctattgcata
    18661 caaaagctgg acagccagct ttagaatatt tgcaaagtcg tgggttgtct ttagaattaa
    18721 ttgaagaatt caacataggt tttgcaccta atgagcgttc ttttcttcag caagtattca
    18781 agaatgaatc aatttcaaat gaattgttag aacgctctgg attgtttgtc acgcatgatg
    18841 atggccgtat gtctgatcgt ttttatcaaa gagtgatgtt tccacttcgt aattctcaag
    18901 gccagacgat cggtttttca ggacgctggc ttgcacctga aaaagggcag gaaaaagatc
    18961 agcccaaata cttgaatagt ccagaaacag aactgttcaa taaaagacaa gttttattta
    19021 atcttgataa agcaagaagc gatatccgga aaaacggaga aattttgttg ttcgaagggt
    19081 ttatggatgt gattgctgca tggcaggctg gtatcaaaac tggattagct tctatgggga
    19141 caagtctaac agctcaacag atccaacaaa tggaaaagct gacgaaagaa ttggtctttt
    19201 gctatgacgg agacaacgca ggttttgaag caaccaatcg agggattgaa ttgcttcggc
    19261 aaaacagtcg cttagcactt tctgtcgtag tcgttccaga aaagcttgat cctgatgaat
    19321 atctccgtaa gtatggagaa gcatctttcc aagaattagt ggctcatggg cgcgaaacag
    19381 tctttacttt taaatcacgt tatttaaaac aagggaaaaa tttagataat gaaaaagaca
    19441 agatcgaata cctcgaagaa ttactagttg aacttagccg agttgtttca ccaatcgaac
    19501 aagatatgta tctatctcaa ctgtcaacag agtttcagat cggcagagag acgatacaaa
    19561 aacaactgcg cgatcttcga aggacaaatc agcaaaatcg tcaagaacct caggaaagtc
    19621 aacacactca ggttacgaga caagaaactg cacggaaaaa gagacctttg acgcaagtag
    19681 aaaaggcaga gcagattcta ttatatcgtg catttaaaga agtttctgtc cgtaatattt
    19741 taaaagaacg agaatttcag tttattcatg atgcatatgc agaagtttat tttttattcg
    19801 atgcatatgt ctcacaacat tatgaattca accttgcaga gtttttagac tttttgcaag
    19861 atgaaaattt aaggcggttg gtggtggaaa tcgaatattt accggtggca gaagaaagtt
    19921 cgccacgaga aatccaagac ttgctagatg tgatcagcaa atctggctta gctgatgaaa
    19981 taacattaaa aaaacaaatg cagcaagaag ccagacgaac tggaaacaaa cagcttgagc
    20041 ttgaattgac gattgaaatc atcaatttaa cgaaacagtt aaaacaagcc aaatagctac
    20101 tcaagggggg ccttctttta tggcaaatgg aacagataaa aaaacgtatg aagcagcagt
    20161 agcagctttc atcaaagaaa acaaacccaa acgacaagtt gtatatgatg atttatccaa
    20221 tcagcttgct acaccattca ctttgaatgc agatgaaatg gacaaattga tccaaaagat
    20281 tgaagacgca ggtatcagtg tggtggatga aaatggtgat ccatcaattc acagcttgaa
    20341 gagtgctgag aaaaaagctg aacaagcaaa aacagaagat ctatctgcgc caaccggtgt
    20401 aaaaatcaat gacccggttc gtatgtatct gaaagaaatt ggccgtgtct cccttttaac
    20461 tgcggaagaa gaagtagcgt tagcattgaa aatcgaagaa ggcgaccaag aagcgaaaca
    20521 gcgtctggca gaagcaaacc ttcgtttagt agtaagtatc gctaaacgtt atgtaggacg
    20581 aggcatgcag ttccttgact tgatccaaga aggaaacatg ggactgatga aggcagttga
    20641 aaaatttgac taccgcaaag gatttaagtt ttcaacctat gctacatggt ggattcgtca
    20701 agccatcact cgagcaatcg ctgaccaagc acgtacgatc cgtattccag ttcatatggt
    20761 tgaaacaatt aataaattga tacgtatcca acgtcaattg ctgcaagacc ttggaagaga
    20821 acctacgcca gaagaaatcg gtgcggaaat ggatcttcca acagaaaaag tccgagaaat
    20881 cttgaaaatc gcgcaagaac ctgtttcact tgaaacgcca atcggtgaag aagatgactc
    20941 tcacttaggt gatttcatag aagatcagga agcaacaagt ccagcagaac acgcagctta
    21001 tgagttacta aaagaacaat tggaagatgt actagataca ttgactgacc gggaggaaaa
    21061 tgtccttcgc ttacgttttg gtttagatga tggccggacg agaacattgg aagaagtagg
    21121 gaaagtattt ggtgttactc gggaacgtat tcgtcagatc gaggctaaag cattaagaaa
    21181 attgcgccat ccttctcgtt caaaacaatt aaaagatttc ttagaataag catgaactat
    21241 tgaccagaag agaaatcagt aaaactgttt ggtttatttt aaaagaaaaa aagcttgaga
    21301 ctacgcagtc tcaagctttt ttttctatag gaaggaaatt cattcattat ttttaagtaa
    21361 atcctaaaaa taagctattg gcgtgacgta tagaatatga tagattaaat ggtagcgtaa
    21421 acctagtaaa ggagccgatc gctaagtgat gaaaaaatgt ccaaattgcg gatcgaaaaa
    21481 aatggagcag aatactatct gtccagactg cggtcatcaa ataactgcag aagatcagca
    21541 aataaaagaa tcaattgaag aaacaaatac agatgcagct atgcaggata aatcaactga
    21601 agatgcagtc tttcctgata cagaattaaa cgatccaatc gaatggtcgg aattgaaaga
    21661 tttacctcta gaatctgtaa tggaattatt cgaaaaagca gaaccagaag acgaagaacc
    21721 acctgctcac gatcaagtaa ctaatataga gaaaaatgaa cagaagaaag caactgttca
    21781 tgagacttcg gaagaatcag gaaagaatca agaagaaacg cttgaatcaa aacaaaaaag
    21841 aagagtagct gaactgaaag aaatcgtcga taatgaggaa gaaaattcga tactatccgc
    21901 ttatatcaaa gcacatcgtg aagatacaaa agaagagcac gcgaaagagc tgctcaaaat
    21961 gatcagtgaa aaaattgcac aggaaaacaa agtagagcca gaacatgaag ctgaaaaaga
    22021 cactgaaaaa gacattagtg gagtaaacgc tgcaggtaaa gaatcattaa aaacgaatga
    22081 tctaaaaacg aatgatctaa aaacggatat cccggaaaaa actgaaacat tgtctgaaaa
    22141 acaatcagaa gacgagaaat cgaatgggtt gccggaagca gataaaaaag aaatgctcga
    22201 aaaagcagac aagaaggcaa cagagtcgga tggaataaat aatgaagccg atgctgaaac
    22261 tcaatctgca agtgaagata gcactgctct tgaagctaaa atagaaaaag aagagaacca
    22321 gcctgagctg attgaagcag aaacagaacc aataacaatc gtgccaaata ctgaaaaaac
    22381 gcctcaagaa tcaaacccag aaaaaaaaga tttagataag acacaaaaga aaaaatcaaa
    22441 aaaagtgccg tatctcgctt tagcagcagt tcttctacta ggtgggggag gctgggctta
    22501 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    22561 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    22621 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    22681 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    22741 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    22801 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    22861 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    22921 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    22981 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    23041 tgctcagttg aatgaacaat tgcaacaagt agataagatg ctcactgata aagagaaaaa
    23101 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagaaaaag cgaaaaaagc
    23161 agctgaagaa caagcaaaac aagccgctca agcagcagct gcagctcaag ccgctcaaca
    23221 agctgcggtc gcacaagcag cacagcaaga agcggcatcc tcgacccctt cctcttcaaa
    23281 ctcagcgaat cagccaatca aatctgccag agcaagtgat attgccgatg catctaatcc
    23341 agcatggacg tgggcaccag gtgtccaaag caaagtgatt gctacatgta tccaacgtgg
    23401 atatatcgtt gaaggaggat acagattaga aaaagccaga atcgaaaatg gggaaggcta
    23461 ttacaatcta tatgccactt caacaaaatc tgcattgatg aaaggcattg gagaaagtgc
    23521 tttgccattt tacatcgtaa ccatcaactg taaaactgga tggttcggag gaaatgggag
    23581 caattaattt taggcaaatg aaagaggctg tgagcctgcc gtttaacacc gtttattcga
    23641 aaaaggggag tatgacacaa ctgttgtcat actccttttt tcacctttcc aaaccaaggc
    23701 tcagctattc aagtagataa cattatgtta tgatagcaaa gaaatgtatt aagaaaacct
    23761 ttcactatag agggagaaaa aaatgaacga tttattagca actatattta caggtattat
    23821 tattgatgaa aatgaaaaaa actactttgt ccaaaaaaac ggacaaacct ttggcttaag
    23881 caaatcagaa ggtgaacaca aaatcggtga agcagtggaa ggattcggct accaaaatca
    23941 aaaacatgaa aatcggatca ctacacaaat tcctaaaagc cgtatcggtc attacgcttt
    24001 tggaatcgtt actgctacac gaaaagattt aggtgcgttt gtcgatatcg gtcttccaga
    24061 taaagacttt gtcgtatctc ttgatgaatt gccgacaatg acagagctat ggcctaaaaa
    24121 aggggatcgc ttgatgattt cccttagagt tgatgcaaaa gaccgtattt ggggcagttt
    24181 agcagatgaa aaaatattca aatctttaag caaatatgga acagaagaaa tgaaaaacaa
    24241 agatgtgata ggaacagcat accgcttgaa attaacaggt acgtacgttt taacggaaga
    24301 tttctatctt gggtttatcc atccttctga acgatataat gaacctcgtc taggcgagca
    24361 aataaaaggt cgagtgattg gtgtccgacc agacggtgta ctgaatcttt cattgaagcc
    24421 aagagcatat gaagctatat cagatgatgc acaaatgatt ttaaccattt tagaacgttc
    24481 tgcagatcag caaatcaact ttacagataa atcggatcca gaagaaatca tgaaagcttt
    24541 tggtatcagc aaaggagcat ttaagcgcgc attaggtaat cttttgaaac aaggattgat
    24601 tacacaagaa aacggtgtga caaaactagt caaaaaatct aattgagaat cccttgcatg
    24661 tttttcttaa ctagcttata ataattttaa ttaacatagt gttatatctt tttttatttg
    24721 taattattat aaattgttgg ggttgagtaa atggtcatga atgctatttc ggcgatgaaa
    24781 aaaacaaaac agcagctaca tgaagcgggg tttaagctga caccgcaaag agaagctact
    24841 ctgcttgtgc ttttggaaaa tgagaaagag catttatctg cagaagaaat cttcttttta
    24901 gtgaaaaaaa agagtccgga aattggactt gctactgttt atcgaaccct tgaaatcttg
    24961 acagaattga aaattgtcga taaagtaagt tttaatgatg gattagcccg ttatgatttg
    25021 agaaaagaag gcgccaaaca tttccatcat catttactat gcttgaactg cggcacgatc
    25081 gaggaagtag aagaggatct tttacttgaa gtggagcaag tagtagaaga acgttatcat
    25141 tttttagtaa aagatcatcg gctaacgttc catggaatct gtcaggaatg ctatgaaaaa
    25201 gaaaaaagaa accagtccgt ctgagtgtct agacggcttt ttctttgctc agattatgga
    25261 aaaagactat cagaatgaag cggtatctga tatgatagag aggcatgagg gggattatta
    25321 tgaaagagca aatcaacgat tatctccact acttgaatat tgaacgggga ttgtccgcca
    25381 atacacgaca aagctatgaa cgtgatttgg aacagtactt gcattttcta caggagcaga
    25441 aaattgcttc atggcaggat gtcgatcgct ttttagtcat ccgttttctg gagaagttgc
    25501 atgaagaaaa aaaagcgaca gcaactgtta ctcggatgat ctcaagtctc agaagattcc
    25561 atcagttttt acggcaagag cgtatcactg atcatgatcc gatgcaacat atcgatacgc
    25621 cgaagaaagc acagaaatta ccaagtacat tgactctgac agaagtagaa aagctgattg
    25681 aagcacctga tacgacaaaa acgttaggga taagagatcg tgcaatcttg gaagtcatgt
    25741 atgctacagg gatgcgcgtc agtgaattga ttggattgaa attgggagat cttcatcttt
    25801 ctcttggact ggtacagaca gttggaaaag gagataaaga gcggatcatt cctttaggtg
    25861 attatgcgat ccaatggctg gaacgctact tagacgaagc acgtccatta cttgtaaagg
    25921 acgcatctga aatgcatgta tttgtcaata atcatgggaa aggtctttct cggcaaggaa
    25981 tctggaaaaa tctgaagcag ctagtacgag aggctgggat ttacaaagaa gtaacaccac
    26041 atacgctgcg gcatagcttt gccacacatc tgctagaaaa tggagctgat ttgcggacag
    26101 tacaggaatt gttaggtcac gcggatatct ctacgactca gatttataca catatcacga
    26161 agaaaagaat gacggatgtt tataagcagc attttccaag ggcttagtca taggaaggtg
    26221 agaagatgtt aacacattac cggaaagaaa accgtaaaat tgctatggga ctattgagtt
    26281 tccataagaa actgacaggt aaaacttctt tgttgaagga gattgatacg tacgaatctg
    26341 aagacgatta tgaacttttt ttctttacgc cagaaggttc aaccaacatt caagggatta
    26401 ttggtgttta ctgggcaacg aacgatcagc tgatcatcca tgacatttct ttgaatccgt
    26461 cttatcgcgg tgagaatatg ggctttcaaa tgttagatga attacaggaa aagtacccgg
    26521 atgtctccat ccgtgcaact gaaatcacag agccttacat tggaaaatgg ctagcaaaga
    26581 aaaagaagaa agagtgaatg agttgacgga gatcaatatt aaattagatg tattcgaagg
    26641 tcctctcgat ctgctgcttc atctgattca gcaaatggaa atcgatatat atgatatacc
    26701 gatcgctacg atcacggagc aatatatgaa ttatatccat acaatgaaaa cactagagct
    26761 agctgttgca ggagaatact tagtgatggc tgctacattg atggcaatca aaagcaagac
    26821 attgcttcct gtccaagaat tcgtcacaga tgatgaagaa ttatgggaag aagatcctcg
    26881 agaagaattg gtcactcagc ttttagaata ccgtaaatat aaatatgcag ctgaaagact
    26941 gacagaaaaa gcagaggaac gaagtcttta ttacacaaaa gaacctatga acatcgatgg
    27001 gttagcggat gctgaaaagc cgttgaagcg aggacaagtc aaaaaaatcg atttgatccg
    27061 tgccatgcag aaaatcttag aacgtaagaa attttctcaa aaagtggaaa aaacgatcac
    27121 gcccgatgac acaacgatcg aagaacgaat ggtatttatc gaagagcgta taaaaagaaa
    27181 tgcgcatggc tgtactttcg attctttttt tgagtcacct tctaaaagtg aagttgtcac
    27241 tacttttatg gctttgctag aattgatgaa aaaagggcag atcattgcgc aacaaaaaga
    27301 aaactatgaa tcaattatgc tttatccagc agtaggagat accgaacatg acgaaattaa
    27361 gtgaacttga agcccttctt tttattgttg gcgaggaagg gatcagtaat gaagaattaa
    27421 gcggactgtt aaatctcagc gaagcagaag tcacaagttt agtgaaagaa ttaaaagaat
    27481 cttacactca aaactcgcac tcagctttgc atatttttga aacggaaagc cattatgtat
    27541 taacgactaa aaaagagctg gctcccttac ttaagcgata tgcgcaaggg acatcaaaca
    27601 cattatctca agccgctgtc gaaaccttag caatcatcgc ttataaacag ccaatcacaa
    27661 gagctgaaat cgagcagatt cgaggagttc aggtttcagg agcggtacag cgtctagctg
    27721 cccataaact gattgaagaa aaaggtagag tagaagggcc aggtcggccg atattatatg
    27781 gaacaactgg ctacttctta gattattttg gtttgaaatc attagaagaa ctgcctgata
    27841 cacaagaaat ggaaatttca tttgaagaag acgtgtcacc agatctattc tttgatggaa
    27901 tgaataaagg agaataattg taatggaaag attgcagaaa gtaattgccc acgctggcat
    27961 cacttctcgt cgaaaagcag aagaattcat ccttgcagga cgtgtaaaag taaacggaca
    28021 agttgtaagg gaattaggga taaaagttgg gaaacatgac actgtggaag tggatgaagt
    28081 cccaatttat caagaagaat acggttatta tttattgtac aaacctaaag gagttatttc
    28141 tgctgttgca gatgacaaag gaagaaaagt tgttacggat cttttgccga tggtaaaaga
    28201 acgtatctat cctgtaggtc gactggatta cgatacttcg gggatcttgc tactgacaaa
    28261 tgatggagat tttgctcagc gcctgacaca tccaaaacat gaagtggata aagtttacgt
    28321 tgcaaaggta aaagggatcg ctacaaaatc gatgcttgca cctttgacaa aaggaataaa
    28381 gatcgaagga cgaaaaacat ctccagctaa attccaaatt ttatcagtgg atcctaagac
    28441 aaaccacagt atcgtggaat tgacgatcca cgaaggacgt aatcatcaag tgaaaaatat
    28501 gcttcaagca gttggtcttc ctgtgcaaaa actaaaacgt gaaaaatacg gagatctgac
    28561 tttacaaggc ctacgtcctg gagattaccg tgaactgaac aaaaaagaag tcagcagttt
    28621 gctgaaccac tcaaaatgaa cacttacttt ttataagtgt tagatgttgc gttttttgaa
    28681 tagatatgta taatgaatat gtaaacaaaa attatataag gttcgtcttc aggggcaggg
    28741 tgaaattccc gaccggtggt tatagtccac gacctatttt gcaaaaaata gctgaatcgg
    28801 tgaaattccg ataccgacag tatagtctgg ataaagaaga tagagcttat ttgacgacgc
    28861 ttgatcaaat aactctaact ctattttccc tggaaaatag agttttttca tttggagaga
    28921 aacgtcaaaa agttcgctga agaggagtcc taacaggagg atttcaaatg aagaacaccc
    28981 gtgtacagaa aatggttgca gtagcgatgt ttgctgcgat cgcgttagtt ttacagtatt
    29041 ttgcttttcc gatcatgccg gcttttagtt ttttgaagat cgattttagt gatatcccgg
    29101 tattgatcag catgttctta ttcggtccag cggccggagt tgcaacagcg ttcttgcgtt
    29161 cagtattaca tctgctgact acaggttttt ctccggataa tttggtagga gacactgcta
    29221 gtttcttatc aacaacgatc tttacattcc cgatttatta tttctttagt gtaaagaaac
    29281 agcataaagg aagaaacaaa tttttaggtg tcattacagg aaccatcgct ctaactattt
    29341 ttatgagtat cgcaaattat ttcgttatta cgcctcttta cttaatgttt ttaggactga
    29401 acgcaacaca gatgctaggc atgtctttag caaactatgt actgattggg atcgttcctt
    29461 tcaacttgat caaaggattc atcgtgagcg ctgtcttttt agtgctgcat gcgcaacttc
    29521 ttccatggtt aagtcgaaaa caacatcagt tcgaacaacg tcatacagca gtcaaataat
    29581 tatcaaaaag atcaagaaat ttcttggtct ttttttttgg aaaaaaatac aagacatgca
    29641 ataatgtaaa cgttttattt gtttgttttg agtatttttt tgatttatgc ataaaaatca
    29701 atcaattctt tgcaaatgtg aaattcttct ccttttaaaa gacgaaaatg tttgtttata
    29761 aaaaaaagga aacgctacaa tgaaaaagaa gaaagcttta aaaacctgaa aaaagaggag
    29821 ggaataggga aaaacgaact ttttgaacaa aagttttaca aaatgcgtgt tattattttt
    29881 gttctgatac tctttttgat aaaataacat tagagccaaa attgttgtct ctaacggaaa
    29941 agaaaggaag aagaagatgg aacaaacaaa aaagaaaaaa tttcaaatgc cttcagcgta
    30001 tacggtctta tttattatta ttgcagtaat cgctgtactt acttggttta taccagctgg
    30061 gcactatagt gtagacgatg caggcaacat cgtcgctgga tcatatgaac gagtacaaca
    30121 aaatcctcaa gggctgtggg atattttcat ggcgccaatc aatgggatgt taggtgtacc
    30181 agcgggggag ctaactaaag aaacacctgc tgcaatccca atctctttct tcattttggt
    30241 tgttggtgga tttttaggta ttatcaacaa aacaggggca ctagatgccg ggattgcttc
    30301 agttgtgaag aaattcaaag gaaaagaaaa aatgcttatt ccagtattga tgctgttatt
    30361 tgcattaggc ggctctactt acggaatggc agaagaaacg attccattct atgctttact
    30421 gatcccagtt atgatggctg taggctttga tacagtagta gcagtagcaa tcgtattagt
    30481 agggtctcaa gtaggctgtc tagcttcaac ggtaaatcct tttgcaacag gcgtagcttc
    30541 acaagctgtt gggatttcga tgggtgaagg tattggtctt cgattcttga tgttcgttat
    30601 tttgttagct atttctattg tatatgtgta tcgttatgca tcaaagatcg aaaaagatcc
    30661 aacaaaatca ttagtataca accaacgtaa agaagatatg aagcatttcg atattgaagc
    30721 aatcggtcgt caagaagtaa tcacgaaaaa acaaaaacat gttaatgtat tgttctttat
    30781 tacttttggt atcatgatca tcagtttgat tccttggaca accttgaatg cgaatttcac
    30841 gatttttgaa tcattgacaa actggttaac aaaccttccg gtactaggta ctgttctagg
    30901 taaaagcatg cttccattag gtgactggta cttcccagaa attactatgt tattcttagt
    30961 aatgtccatc gtagtagcaa tcacttatgg catgaaagag tctgaatttg tctctgaatt
    31021 tttagctggt gcttctgatt tgatcggtgt agcaatcgta gtagctgttg ctcgtggtat
    31081 ccaagtggtt atgaacaatg gattaatcac agacaccatc ttacattggg gcgaacaagg
    31141 attaagttca ttatcttcaa gtgtattcat cattattaca tttattttct atatccctat
    31201 gtcattcttg attccttcaa cttccggctt agctgctgca acaatgggaa tcatgggacc
    31261 tatgggtgaa tttgccggcg tcggtaagga tttagtaatc actgcttatc aatctgcatc
    31321 tggtttagta aacttaatta caccaacatc tgctatcgta atgggtgctg tagcaattgc
    31381 tcgtttcgat gtttcagtgt ggtggaaatt taccggtaaa ttaattgcga tattatttgt
    31441 agccatctgt gtgatcctag gtgtagcagc aatgttctaa acctagacaa atacaggtac
    31501 aaggtctatc ataagaatga agaaaccgat aaacggctat cgataagcac gtggacaagt
    31561 caatagctcc attcagtgag tgttttttct ttcatcattt gttaagaaca ttctgcttgc
    31621 tgatggagca ggcttaaaac gtcattattt gagaagaaga ggttgtgtcg gaggaatttg
    31681 acatgaccct ttttaacata ttaggaggat aatatcatga aaaaatttgt gacagaacaa
    31741 catcatgaac aagcattaga atcattgagc gaattgatcc gaattccttc cgtactagat
    31801 gaagcagatt caggacaagg acatcccttc ggtaaaaaag tgattgaagc tttggataaa
    31861 gtattggaaa tcagtgaaaa gctaggattt agaacattta aagatccaga aggctattac
    31921 ggttattcag agattggctc tggagatgaa ttattcggta tcttgtgtca tatggacgtt
    31981 gttccagcag gggacgaaaa taattgggaa acaaaaccat tcgatccaac tataaaagac
    32041 ggctggttag ttggtcgcgg atcccaagat gacaaaggtc cttctattgc ggcaatgtat
    32101 gccgtcaaag ctttgattga tgctggcgtg gaattcaaga cacgtattcg ttttatcttt
    32161 ggtacagatg aagaaaattt atggcgttgt ttagaaaaat ataacgaaaa agaagaagga
    32221 attacgcaag gatttgcgcc agatgctgaa tttcctttaa tttatgcaga aaaaggctta
    32281 ttgcaagctt acttgacagg accaggaacg aacgagtttt ctgtaaaagc tggaggagcg
    32341 ttgaatgttg ttcctgatgc agctccttac tctggagaaa agctttctga agtaaaagaa
    32401 gcgttgaaaa aacacgaatt cgatttcgaa gaacaaggtg aaggcatcgt cgttcttggt
    32461 aaaagtatcc acgcgaaaga tgcagcacaa ggagtgaatg ctatttctcg tctggcaatt
    32521 gctctttcag aagtattcga ttttggccca atcaatttct taggaaaatt agttcaagaa
    32581 aatgcaactg gtgaagctgt cgtgggcaaa acagaagatg aacaatccgg cgagctaacg
    32641 atgaactttg caagtttgga aatcacacca gaacaaacaa aaatcggtgt agatatgaga
    32701 atccctgtta cattcaagaa agatgattta gtagctaaat taactaaaac agcagaaaaa
    32761 tatgggttga cttatgaaga atttgacttc cttgattcat tatacgtgcc actagacagt
    32821 gagttagtga aaaatctatt ggggacatat cgcgatatta ctggagacat gactgaaccg
    32881 tttgtatcag gcggcgctac ttttgctcgt acgatgaacc agtgtgtggc attcggtgcg
    32941 atgttccctg atactcctga ctttatgcac caggcgaatg aacgatggga attaagtagt
    33001 atgtataaag caatggaaat ttatgcagaa gctgtgtatc gtttatgtgc taaataaaaa
    33061 taaacataca aaaagggcgg atattcaaat ggatattccg tcttttttta tttgatgctg
    33121 gaaagtttgc atttctctct tatttttttt aaggtataat catacttgat taagaaaaag
    33181 gggtcactca gatagaaaag gtgggagaaa gtgaaaatat ttagacgaat actaattggc
    33241 ttagtcatca ttttaggatt actcggtgga gccggttatt actatataca gcaaaatacg
    33301 tacgaaccat cgtcagaagc gcaagtgttg gtaaaagaag gaaaaaacaa agaagattac
    33361 ttattttttg aaggagagaa aaagaatcat ggaaattctc cattacttat tttttatcct
    33421 ggtgctctcg tagagccaga aagttatagt atttgggcgc aagatttagc aaaaaacggc
    33481 ttttcagtcg ctattgtcaa aatgccactt gatctagcag tgatgggcgg aaacaaagcg
    33541 gataaggtca aagaagattt tccaaattcc gattatgtga tcggtggcca ttcattaggt
    33601 ggcgtaatgg caagtcgtta tgtcaataag aatcattcag acaaacattt aaaaggggta
    33661 ttcttcatgg caagttatcc cgacaaaaaa ggaacattga cagaatcagc tgttcctgtt
    33721 ttatcgatca cggcgacaaa agataaagta ttgaatcagg aagcttatca agaagctaag
    33781 cagtatttac cggaaagaac agagtatgta tcaatcaatg gcggaaatca tggaggtttt
    33841 ggcagctatg gtgagcaaaa aggagatgga gaggcagaaa tttctaacgc agaccagcaa
    33901 actgtgatcg tcaatacatt ggaaaactgg ctgaaaaagt tgaaataata taaatgggtc
    33961 ctatagggtc cgtgaaaaaa ctagtcaatt aactatagat agcaaatgaa tctttcaaaa
    34021 taagtcggga tttcacggaa caagagaaac agatcccggc ttattttcaa gtttagagaa
    34081 cttagtgtac gtttttaaag tttcgtttat atttatattt tattttctaa taaaatcgct
    34141 cgaactggac atttttgata cgcttttttt acatatgttt cttcttccgg catcacgaac
    34201 tgttgatgag cctctggttc ttgggcaaat aaaacgattc cttcttcatc ataatcgaaa
    34261 atatctggcg cttcgatttg acaaagaccg catgcaatac agcgttcagg tacaagttta
    34321 catagtagtg acatttctaa ccatcctaac ttaaggagaa taatatgatt gtttttattt
    34381 tatcgctatt ttcatcagga cacaagctgc ggattagttc tctttaccaa ctccttgtgg
    34441 gaaaacgaac gacttcagta cttatttatg gatttaccca cgaacttttg tttatccata
    34501 acagttttcc agaattgaag caggataagt tttatcaaat tttgcaaaaa attgcgcagc
    34561 aaggttggat cgaaataaat gaaaatgaag caaagctaac gcctgcaggg gctgatatgt
    34621 tgtccgaaca tcaaatagaa catactggtt tgcgttttga ccgctatggc agaacagggg
    34681 aaactagttg gcggctcatt aaatttgctg ttcaagtaat ttctaatctg gcaacgggta
    34741 ttcaagacta tcttccagca gagacaagtc ctttttatac tttccaacta aaaaaatggc
    34801 ttagtgaaag ccaattgcca cgtgaaattt tgattgatac tgcgtatgag agtttggtgc
    34861 agctgttttc ggagatacca gaagaagcag cagatttttt agctaaccaa ttatctggaa
    34921 atgagcgaac agggctgctt ccttatcagc tggcaaaaaa caatgatgag tcagcggttt
    34981 atctgcaaca aagcagatgt atccaccttt tgttagcaca aatcgaaaaa cggccagatt
    35041 cgctttggca cgctttgatc gattcattat tacagcaaaa tttcaatcaa agcatgatga
    35101 tcaccaagca gatgtttatg aatggtcaga caattgacca gattatggca atccgtcatt
    35161 taaaaagagg aacagtaaca gatcatctta ttgagtgggc cttgtttttt gatgattttc
    35221 catacgagcg gattctctct gcagaaacaa tcgaacgttt ggaaccaaat aaggattccg
    35281 tgcgagagtg gcgctttagc gaatggaatg tagatggaca attagattat ggagaatttc
    35341 gtttgtatca aatctatcta ttgagaaagg aagcgataca gaatgttaat aaatgaatta
    35401 aaaaaatatt ttggatttga ttcatttcgt cccggccaag aagaaatcat tcaggcgttg
    35461 cttgatggag aagatactct cgctattttg cctacaggaa cgggaaaaag cctttgctat
    35521 caattgacgg ggtttttaat ggaaggtctg gtcatcatcg tgtcaccgct gctttctcta
    35581 atggaagatc aagtgacgca attacaaaaa cgaggggaga aacgagtagc tgctttcaat
    35641 agtttacttt cgcaatctga aagaagatac gtcctccgtc atctatcgca atataaattt
    35701 ttgtttttga gtcccgaaat gttgactaat ccttctcttt tagagcatct gaaaaaacaa
    35761 aatattgcgt tatatgtagt agatgaggct cattgcgtgt ctcaatgggg agttgatttc
    35821 cgtccagaat atcaacagtt aggaaaaatc cgaaagcttt taggaaaccc ggtcacactg
    35881 gcactaacgg cgacagcaac agatttagta gcaagagata tacgtcatgt actatttgat
    35941 cgaccaccaa aagagatcag acaatcagtc aatcggcaaa atatctcgct ttttgttcgg
    36001 aaaacgcagc aaaaagaaca agaacttgaa cacttcatgg aaagagcaca aggagcggca
    36061 atcatttatt gtgcaacaaa aaaagaagtc gaacgattgt atcatttatt cagggaacgt
    36121 tttacagttg gatactatca cggtggtctt gatgcagctc aaagaagaca acttcaacag
    36181 cagtttgtaa aaaatcagct gcagtttctc attgctacga atgcatttgg tatggggatc
    36241 gataaatctg atatccgtta tgtgatccat tatgatttgc cagacagtct agaaaactat
    36301 gtacaagaaa tcggtcgagc aggcagagat caggaagaaa gtgcagcaat tcttttttat
    36361 caaagtgggg atgaacgtat ccattatttc tttaatcaac tttctagaga acagcgacaa
    36421 agttttgagc tttatttgga atatgccaca gagcaagctc cctttgatga gctgcaaaaa
    36481 aaatggatgg agctgatcca gcagtctgaa aaaccagaaa attgggtgga acggctcaaa
    36541 cgtcaggaaa aagaaaaaga attccgcctg cagcagatgc ttcgctatat taatgaagaa
    36601 aactgccgca gaaaattcat cttagcttat tttggcgaaa aactctccga aaagccgcag
    36661 aattgttgtg atattgatgg agcaaaagca gaacttctgc caaagaggaa gcttttttct
    36721 aagactgaac aacttcattg ggaaacgatt ttactaaatt tatttaaaaa aaacatggaa
    36781 cattgatttt ttaggacaag acactttttc ctatggtata atacacacga tagagtttag
    36841 gaggtaaaac agtgagcaga aaagatagac atcaatctac agaaaataac gaaacacaag
    36901 aaccatggga acaaccaatc tacgatacag atgatgaagt ttcatcaaga agttctcaga
    36961 gacaacaaaa gaaaggaaat acattatttc tttcgctatt tttgatttta ctggtcttat
    37021 gtatcgctat tccagcaggt gcttatttct ggatcagaaa tggatcaagc aacaatgcaa
    37081 cagcagcaac ttcttctgaa acttcgacat cagtagtaga aagttctaca agtacaacaa
    37141 aagaggagtc aactgagact tcaacagtag aatctagtac aatcgcggaa gaatctactg
    37201 tgtctcaaga tacaggtgta acgtcagaaa gcagtattgc agcagagaca acaccgactt
    37261 cctcaagtga ggcaacttat caagcagggg attcaagcag caatgcagca gaaacaacac
    37321 cttcttcatc agctgcagcc ggttcaacaa cgactgttca agcaggcgaa ggtccaaaac
    37381 aagtggctga gcgtgcaggg atcaccactg atcaattgtt tgaattgaat ggcttagatc
    37441 caaacaactt tatgctttac cctggtcaag aattaagaat taaataataa tagccgcgct
    37501 ttgcggcttt ttttctgaga aaaaggagtt atatcatgac acaaatcagt attgcaatcg
    37561 acgggcctgc ttcatctggg aaaagtaccg ttgccaagat attagcaaaa gaattgaatt
    37621 atatttatac agataccggt gccatgtatc gcgcagtaac ttatttagct attacgaaca
    37681 atgtatcttt ttcagatgaa gaagggctag tttcgctgat caaaaagtat cctatctctt
    37741 tttcgcaaca agaagatgga cagcatgtat tcatagcatc aaaagatgtg actttagaaa
    37801 tccgtcaacc agatgtcaca aaagctgttt ctgaagtctc tgcacatgga aaagtcagag
    37861 aagaattagt tgctgtccaa cgaaaaatag gggaacgcgg tggcgttgtc atggacggaa
    37921 gagacatcgg gacagctgta ttaccgaatg cagaagtgaa aatcttttta gtagcaagcg
    37981 taagtgagcg tgcagaaaga cgtttcaaag agaaccaaga aaaaggaatt ccgactgatc
    38041 ttgaaacact gacgaaagag atacaggaaa gagaccatta tgattcaaca agggacgtct
    38101 ctccgctgaa gcaagcagag gatgctgttc gtatcgatac gactggcaaa tcgattccag
    38161 aagtcgttgc agcaataaaa gctgttgttt tgaaaaaagg ttatcttctt ttttaaatta
    38221 agaaaaaaaa tgaaaaacaa ttgttttttc aaggaaaacg aacgaaatcg ctttattttt
    38281 tttgaataat caattaaact aaaaacagta ccgtacttac ggcagaatgt tggttaggag
    38341 gacaagtgtt atgacagaat ttgatcaaaa tcaagagaac aaccagtcaa tggaagacgc
    38401 aatgaaaagc gtacaagaag taaaagttgg cgatgttgtt aagggcgaag ttttagtcat
    38461 tgaagacaaa caagtgattg tcggaatcga aggggctgga gttgaaggag tcgttccggc
    38521 aaaagaatta tcaactttgc cggtagaaga tatcagcgaa gtagtaaaag tcggtgatgt
    38581 attagattta gtcgttatca gtacgatcgg caaagataaa gaaaacggca gctatctact
    38641 ttcaaaacgc cgtttagatg ctaaaaaagt ttgggaagat atcgaaagag atttccaaga
    38701 gggcaaggtc atcgaagcac ctgttacaaa tgttgtcaaa ggcggtttag tcgttgacgt
    38761 cggtgtacgt ggttttgtcc ctgcatcaat ggtggaagat cattttgttg cagacttttc
    38821 agactataaa ggcaaaacat tgagctttaa aatcatcgaa atcgaaccat cagaaaatcg
    38881 tttgatctta tcgcataaag cggtagtgga aaacgaaaga gaagaaaaga aaaaagaaat
    38941 tctttcaact atccatgagg gagatgttct cagtggacgt gttgcacgtc ttactgattt
    39001 tggcgcattt gtcgacctag gcggaattga cggtctagtc catgtctcag agatttcaca
    39061 tagtcatgta gcaaaaccaa gtgatgtatt ggctgtcaat gatgatgtaa atgtcaaagt
    39121 gttgtctatc aatcctgaac aagaacgtgt ttccttgtca atcaaagaca cacagcctgg
    39181 accttggtca gaaatcgata caaaagctcc agttggcaca gtattagacg gaacagttaa
    39241 acgtttgaca agcttcggtg cctttgttga agtgttccct ggagtagaag ggctagtcca
    39301 tatctctcaa atttcacata aacatattgc gacaccacat gaagtgcttc atgaaggtga
    39361 cgaagtgaaa gtgaaagtat tagagatcca tccagaagaa catcgtattg cattgagtat
    39421 caaagcttta gaagaaaaac cagcttcaga agaagaacca aaaaatgttg agtcttatga
    39481 attaccagaa gaaaatactg gatttactat gggagacatt ttaggtgatg cgttgaaaga
    39541 agaagtagaa gaaaaagcaa ccgatgattc tgaaaaataa ttgattttgt atctgtgact
    39601 gagatgaaag cagctgcttt tgtctcagtt tttcttttga aaagcgatta gtatttcaat
    39661 aaggaataaa aatacttcgt ttaattgaca atctatgctt gaaagttggc aatgcattcg
    39721 ttaaactaag tgagattgga aacttgtgag gaggaaataa tatggcaaat ccaacaattg
    39781 caatcgttgg ccgcccgaac gtcggtaagt ctacgatttt taaccgcatc gctggtgagc
    39841 gtatctcgat tgtcgaagat actcctggag taactcgtga tcgtatttat gcaaaaggtg
    39901 aatggttagg tcgagaattc agcgtgatcg acacaggcgg aattgatctt ggcgatgaac
    39961 cttttatgga tcagatcaag catcaagcag aaatcgcgat tgaagaagca gatgtaatca
    40021 tttgtgtagt cagcggacgc gaaggcgtga cagacgcaga tgagatggtt gcgaaaattt
    40081 tatacagaag taataaacca gtgattttag cagtcaataa agtagataat ccagaaatga
    40141 gaaacgatat ctatgaattt tattccttag ggctaggcga tccttatcct gtttcaggaa
    40201 gccatggact agggattggt gatattttag atgaagcagt gaagtatttc tctgaagaga
    40261 ctgaagaaga ggacgacgac acgattaagt ttagtttgat tggtcgccca aatgttggta
    40321 aatcctcttt gatcaatgcg attttaggag aagaacgtgt aattgtttcg gatattgaag
    40381 gaacgacccg agacgcaatc gacacccact tcgtttctga aagtggtcag aaattcttaa
    40441 tgatagatac agctggtatg cgtaaacgcg gaaaagtata cgaaaatact gaaaaataca
    40501 gcgtgatgcg tgcaatgcgt gccattgacc gttctgatat cgttttgatg gtactgaatg
    40561 ctgaagaagg gattcgggaa caagacaagc gagtagcggg ttacgcccat gaagctggtc
    40621 gtggaattat tatcgtcgtg aataaatggg atcttgtaaa gaaagaaacc aatacaatgc
    40681 gtgatttcga acaagagatt cgtgatgaat tccggtatct tgattacgct ccaatcgttt
    40741 ttgtttctgc agtgactaaa caacggttgg aacgtctgcc tgaaatgatc gaacaagtaa
    40801 gtatgaacca gaatcttcgt atctcttcgg ctgtgttgaa tgatatcatt atggatgctg
    40861 tagcaatcaa tccaacacca acagataaag gaaaacgcct gaagattttt tatgctacac
    40921 aagtcgctgt caaaccacct acatttgtcg tttttgtcaa tgaagaggaa ttgatgcatt
    40981 tttcttatga acgtttctta gaaaatcaaa tcagaaaagc atttactttt gaagggacgt
    41041 ccatccgaat tatccctcgt aggagaaaat aggcatttta ccatatcgac gttttttttt
    41101 caaaagaaaa agacagtttc gtttgttacg tttctatgac taaaaaaagc atgtgaaaat
    41161 tggtaaaaac cttgctatta agcggttcat atgatatcgt gataacagaa tattgaagtt
    41221 aatcaatatt tctttttaaa cttctggacc actcagaaag ttttaactaa atgatatttc
    41281 tatcatatct cttgtggagg aggtgaatct atccatggca aacaaagcag aattaatcga
    41341 aaaagttgct tcagctactg atttaactaa aaaagatgca actgcagcag tagatgctgt
    41401 attttcaact attcaagatg ctttagctaa cggcgaaaaa gttcaattaa tcggttttgg
    41461 taactttgaa gttcgcgaac gcgcagctcg caaaggtcgt aacccacaaa ctggtgaaga
    41521 aatcgaaatt ccagctagca aagtacctgc attcaaacca ggtaaagcat taaaagacgc
    41581 tgttaaataa gacagttgaa aaagcgcttg tggctctagg gctacaagtg cttttctttt
    41641 tatttcctag cagaaaagga ataaataaga gacagagatt ccgaatccgt atgtcataca
    41701 tagaaaacac atgtatttta tttaattttt atttatttgc aagttatgag gtgagctttg
    41761 ctcttatctt ttctagaatt tgcttactaa tggtaaaata aaaataagaa gaggagggat
    41821 gcgtatggaa cttgattatc aagtagaaga tgcgttgacg aaagtgtttt acggagaaac
    41881 gctagtcagt cagctaagag aactttccat tgatcagcca atcttatttt taacgaatca
    41941 gcgctattat gatttgtttg cagataagat caacccgtta tttgcaaatc aagcaaacaa
    42001 tgactggtat atttgtgcca acactcaatg caatcattta acagaattaa agaacctgct
    42061 tgatttcgtc aaacgctatc ccgaaaatca atccatgttt atcatcggat ttggaaatga
    42121 agggatcatg gatctggcag gtttttttca aaaacataca acccttgatt catcactatg
    42181 gatgatccct gtatcgatcc gttctctaag ccgagcatta acaccgcagc ggacgatttt
    42241 gcagctacca aatcgtgtag tgctgcaaac catcaatctg ccagaacgca tcgtttatga
    42301 tcaaacaatc agcgagcggc aggtggacgg aaagcagatt gactttttga cttttatctg
    42361 ttgcggaatg atttgtgatc atcgtttttt gcaaaatctg tataaaaact atccaaataa
    42421 aaagcaatta acgactcggc cgtttgccgg gatgatcgaa gaaatgatct atttttatca
    42481 attagaggca gaaaacctgt caaattatgg taaactgttt gaacaagctt tttatctgac
    42541 cgaaaatggc catctacttt ctgctagtat gaaaaaattt ttaggaatga tgtttcattt
    42601 cgtgtggaat ctccaagcat atccttttga tttccaacta aaaaactttt ttgtgtggct
    42661 ggacttgctt ggctatccaa tccactggct ggaacagatt tcaaagatgg agtatttgga
    42721 aaaagttctt tttttggcag aaaaaagcaa aaaaatactt gttttagaaa aaataggtat
    42781 aatagacgga taccaacatc caaacgaaaa agaattattg agaacaatga cggtatttca
    42841 acaaatcgtc agtgagataa gagggaattg aaatgaatac aaatagcgaa aaaatgttgc
    42901 aagctttatc agatgaagac ttgtcacaag cacaaatctt tttagaaaaa gcattaaaag
    42961 aagacccagc agatatatta gctgaactag gcgaagaatt gctggctatt ggctttttga
    43021 tcgaagcaaa acagattttt gaacaactga tcaaccaata cccagaaaat gacggactga
    43081 acatcccgtt agcagaaatt gcaatcgaag ataatgagat cgacttagct tttgaatacc
    43141 tggaaaaagt ggataagcaa agtgattact atccgcaaag cttattggcg atagctgatt
    43201 tgtaccaagt tatcggaatc cctgaagtga gtgaagcaaa attgaaagaa gcagctgggt
    43261 tgcttcctga tgaaccattg atccagtttg cgctagctga attgtatttt tcagttgatc
    43321 gtttcaaaga ggcagcagtg gtttatgaaa cattgttggc aagcgggata aatgaaattt
    43381 caggaatctc gatgcaggaa cgtttaggac aatccttaag tatgcaagga gaattcgaag
    43441 cagctatcgt acctttagaa gaagcactga aagaagaaag gacagatgat cgactgttcc
    43501 agctagcttt tacgaatctt caattgaaag aaaatcagca ggcaatcaac tatctggaag
    43561 aacttcgaga agttaatccg cattatcaat cgttatatct atatctagga caagctcttc
    43621 aagaagaaga aatgattgaa gaagcacaaa cagtgttaga agaaggaatc aaagaaaatc
    43681 cttaccaagt cgaactttat cacctggcct cggaaaatgc tttccgtctg catgatagac
    43741 agcgagcaga agaactttta ctgaaagctt tagaagtagg agacaaacaa gatgaaacat
    43801 tacttacttt aagtaatctt tacttggatg atgaaagata tgaagatgtg atacaagtga
    43861 tcaatcagat ggaagaaact gctaatcctt atgcagaatg gaacctagcc catgcttata
    43921 atgaattaga agactttacc gttgcagctg tacactatga acaggcttat catgaactat
    43981 cacatgaacc agatttcttg aaagagtatg cctttttctt aagagaagaa gggcagctga
    44041 aaagagcgca agaattattg acttattatt taacacttga accaggagat atggaggcac
    44101 tgtcattatt agatgaccta acagagaggt gagaaaaatg ctaattgatg tacgggaaaa
    44161 gaagaatttt ttaacgtgga tggtcaatca tgtatctttt agccgaagag aagttttttg
    44221 gatcttgaat tatcttgcca atcatgaagc gattttaagc aatgtccact ttgttgaagg
    44281 ggcgaatttt gcggatcgag gactgcagat cagtgatcta tctgttgaag gggaacccat
    44341 gaaattgttt ttgcagggaa aagaatttac ggacacagac cagatttttc atgaaatccg
    44401 tttgaattgg aaaaagcctt tatatgtgga atgtatattc gaaaatgctt ggcagacaag
    44461 agaatatcta tctatcttag aagacaatcc attttcttct tgggattctt cagtcagtga
    44521 agaagatact gaattaattg aacgatattt tcaagaaaaa gaagaagagg caaaactaaa
    44581 aatgctttat gctcaaatcg atcaagcact agaagatgga gatagggatg cttttttgaa
    44641 attatctgat gaagttaacc gaaagatcct tttgcagaca caaaagaaaa gtaaccgggt
    44701 aagtgaacat aacaattagt taaaaatagt atagtactaa aaaagacaaa ggtcagctgg
    44761 atgtggaatc tttcctcata gcctatcttt gtcttttttc ttatagtttt ttcagtaatc
    44821 ttgtctgtgg cttcaaataa gtaaagcctt gcccttccac ttcatgcaca ttgatgattg
    44881 aaaggaaagc tttttcgtca atctcgtgga cgatcctctt agcttcagtt aattcactag
    44941 agctaacgac catatagatg attttttttg aattaccaga gaatgcgcct tctccagaaa
    45001 ggaaagtcac acctctttgc agaccggtca tcagtagtgg tgcaatctct tcgcttttgt
    45061 tggagacgac aagtagacct tttgcagaat atccgccatc taagatcgaa tcaatcacac
    45121 gactgaaaac atacgaaaca atcaacgtat acatcatacg tttcaagtcg atataggtta
    45181 atgaagcaag taagacgatg atatcaaatg ccaataggga acgccccata gtgatgccgt
    45241 aattttgttc taaaatccga gcgataatat cactgccgcc tgttgttcca cccatgcggt
    45301 agacgatccc gcttcctaca cctgcaacta aacccgcaag tagagaaacg atcagtagat
    45361 catgctgtaa attgatttct agtggaaccc tttgccagat ccataaaaag aatgacaaag
    45421 aaagtgtacc tagaacagta taggccaagg aacgtttacc gaggatcttt cctcctagta
    45481 aaatcaatgg gatgttgatt aataaagtcg tataagctgg atcaatacca aataaagctc
    45541 ttaagatcaa ggtgatccct gagactcccc cttctgctaa atgattagcg atgttcaagt
    45601 aaacaagacc aaatgcataa atacttgttc ctataatgat aaaaagaact tcttttactg
    45661 tttttcgttt gaccatatga attccagctt tcaattatgt attttcacag aatttccatt
    45721 tagaaattcc ttcctaaatg tagcatggaa attcgatttt ctcaattgct cttatctagg
    45781 atttgcgtta aagttttggt aagatagttt tggagggaaa aagatggata aaaagcgttc
    45841 tttatacagt atgcagcagg aagtggatga atatatccag caattcaagg tggggtattt
    45901 ctctccatta gctcagatgg ctcgattaac tgaagaagta ggtgaattgg caagagaagt
    45961 caaccacact tatggagaaa aaagcaaaaa ggcttctgaa ccagttaact cggtagcaga
    46021 agaacttggt gatgttttat tcgttacgat gatcatggct aattcattga atatcgactt
    46081 aactgaagtt tttgaaaaaa acatggaaaa attcaatcaa agagaccata atcgctttga
    46141 gcgtaaggac gagtaaacaa gatgaagtgg tcctggcctt gaagactctg aaacggactt
    46201 gtcaaacagt caccatgcaa ctgagtcttt atctcaggac aagaaacacg caggaaaggt
    46261 tggaaaaatg aaattaaaac aattacctct ggaataccaa aaggcaattc cagttctgaa
    46321 aaaattagag aatgcaggat atgaagctta ttttgtaggt ggaagtgttc gtgatatctt
    46381 gctgaaccag ccaatccatg atgtggatat cgcaacaagc gcatttccag aagaaatcaa
    46441 acagcttttt ccaaaaacga tagatattgg gatcgaacat ggaactgtgt tggtattaga
    46501 aaatgatgaa caatatgaga tcaccacatt tcggacggaa tcaacttatc aggactaccg
    46561 tagaccagat catgtcgaat tcgttcgttc gttggcagaa gatttgaaaa gaagagattt
    46621 tacgatcaat gcgtttgctt tgaaagaaga tggagaaatc atcgatttgt tcgatggtct
    46681 gcaagatcta gaagaacaga tcttgcgagc tgtaggcaat cctcatgagc ggttccatga
    46741 agatgcctta cgaatgatgc gcgggttgcg ttttgtcagt caactagggt tcaaattaga
    46801 ggaagaaacc ttctacgcca tcaaagaaaa ccacgagcta ttaggtaaaa tatctgtaga
    46861 acgtataaat gtggaattca tcaagatgct cttgggaaat gaacgggccg cgggaatcca
    46921 tgcatttatt gaaacagagt gctacatttg ctgtcccggt ttgaaagaag aaggcgaagc
    46981 acttttacgt tttgctgaat taccatccgt cccattgaaa gaagagagcc aagcatgggc
    47041 attattgatc agccaactgg atctaaaaga aaatgagatt cgttcctttt tgaaatcgtg
    47101 gaagtgttct aaccaaatga ttaaagacgt tcaagcactt gtccaaggac tacgacaacg
    47161 agaaactgga gctttggaac cattcgaatt gtacttctta ggcaaaaaac atgcactgca
    47221 agtagaagaa ttgatgatct attttgacga aacacctcag atggatgccg taggagaatc
    47281 ctatgatcgt ttacctatca agtcattaag cgaattagca gtagatggta aaatcttgct
    47341 agaagaaact ggaaaaaaac ctggtaagtg ggttagtgaa gctttgcaat tagctgaaaa
    47401 agccgtcgta gaacaaagaa taaaaaatga taaaaaacag gttttggatt ttttatcgaa
    47461 agaaaaattg atttaaaaaa cactagactg tatctgctca gctttgttgg ctacttaaag
    47521 tgggcagata cgtcattaga agaaaaaaca taagatgtga ccacttacat aaatttgtgc
    47581 taaactgagg tagtacaaga ataaattaca tcataaagga gtctttttaa tgagtaaaga
    47641 aatgacagcg ctaaaatttt attttagaaa tggagaaacc tggacgatca accgccgtca
    47701 tatcggcgat ctttggatca aacaaatcac aacaagtttt ggacgaatca atggcagtga
    47761 atttgttgaa atccatccgt gtgctggatt taaaatcgaa atcttccatg aaggggacgc
    47821 agttgcgaca catgatatca acctaggcgg actggaaatg ggcatgttta atcgcgcatt
    47881 gaaatacgaa gatatcgagc gaatggaaat cctttaccga aatggcacac ctgatcttgt
    47941 gtacttccca tatctagata aaggaacaga aggattagac aatcaatatc aatcaacaaa
    48001 aatcagcgaa aaaacaggta acttgtatat cgtgatcaat ccagatcaac gtgtagaaga
    48061 tgtatacggg gaatttttcg aataaatcga tttttacgca aaaatgaggc tgtgaaagag
    48121 atgtgtctta ttactactga taggctgtct cttccacacc gtttattcag aataagggac
    48181 tgtgacaaga tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca
    48241 ggaatgggaa agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga
    48301 tatctgatac tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag
    48361 caataaacga tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg
    48421 aagtttgtgt ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt
    48481 tgcatgatcg ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc
    48541 gtaaaagaaa tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt
    48601 tggagtcaaa acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg
    48661 aaaccaaaat tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat
    48721 aaaggggatg gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct
    48781 tatcgaacat agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc
    48841 ttggagtggt attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt
    48901 tcttagttat gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt
    48961 cgattctcaa aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc
    49021 ttgtcggggt aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct
    49081 ttgcttttgg agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac
    49141 gagtgaatat ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg
    49201 catctggtgt tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag
    49261 cagtaaacgc ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt
    49321 tgcttgtctg gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg
    49381 tcacagggta tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg
    49441 catttgatgt atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt
    49501 ttaggaaaat ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa
    49561 ctattgcttt tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag
    49621 tgttctcgcc agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg
    49681 tattaatctc tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat
    49741 tcaaagatgg cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg
    49801 gcggtgtaaa gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata
    49861 atatgatgtt ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga
    49921 ctttggtcat agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca
    49981 cggatttgaa tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa
    50041 aggaaattga tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc
    50101 aagaacggat acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac
    50161 aagaaataca agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt
    50221 cgggcaagct ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac
    50281 attctatcac aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt
    50341 taatgcgaat cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga
    50401 catttattag tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt
    50461 tgattattga aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt
    50521 ttatccagca acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt
    50581 ggatgatcca gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa
    50641 gaaaaatcat tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct
    50701 atcgcaggaa tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt
    50761 ctttccgatt tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta
    50821 aaaattttca agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt
    50881 ctttttttga gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt
    50941 ttatgataca atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc
    51001 tcaaaaaaac ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa
    51061 aagaccgtat cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta
    51121 ttgccggtat cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc
    51181 gtattggtta tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag
    51241 tctttcaagg aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg
    51301 aactagggga aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac
    51361 aaatgaataa agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat
    51421 taggaatcag tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag
    51481 ttagtctggc gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa
    51541 accatttaga ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg
    51601 cactattgat ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg
    51661 aactttcatt tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa
    51721 aagcagaacg tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac
    51781 aggaattagc ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga
    51841 tcaaccgttt cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag
    51901 agctgaacct agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt
    51961 accgtataaa tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa
    52021 gactaggtat tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg
    52081 gcagaattcc cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt
    52141 atacacaaga aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag
    52201 ctgctgaaga agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac
    52261 gatttttatt tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa
    52321 aacgccggtt atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg
    52381 aaccgaccaa tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt
    52441 ttccaggtgc tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata
    52501 agttattagt attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt
    52561 atttactgaa gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga
    52621 gcaaggaacc tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga
    52681 ttgaagatga gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc
    52741 atcaaggaga taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag
    52801 cacaacttga agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg
    52861 aggaaaaagg atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca
    52921 tcgtaaagaa gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt
    52981 tgatctgcaa aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa
    53041 aagcgaattg ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa
    53101 aaaccatatt tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg
    53161 accagatatg actgattttg gccatagatg tttgacagat cctgaattca atgaagaata
    53221 taaaaagcag agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac
    53281 atacggcgat cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg
    53341 tggctttatc gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag
    53401 aagattgatc gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg
    53461 tcatacgatg tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg
    53521 cagtggggat gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca
    53581 cctaattgca catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc
    53641 tcatctttat atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc
    53701 atttccgact ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga
    53761 tatccaatta gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa
    53821 tcagaaagga tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg
    53881 gaaaagaaga ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga
    53941 cagaagcaaa tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt
    54001 tgccgaatcg tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc
    54061 atgtcatgca tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt
    54121 tcatcgctgg agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc
    54181 gtacagtcat ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg
    54241 attggtcact gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc
    54301 aatttgaaac gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga
    54361 tataaaaaag ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt
    54421 ttttttatta agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa
    54481 acaaatgcca aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta
    54541 tcgtgtaaga aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat
    54601 aaagaggaac agcagccacg acacagagcc accccataaa aatatagatg atcgtagata
    54661 cttttgatac tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg
    54721 caaacaacca gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac
    54781 aaaaaggagt ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga
    54841 acaccttttt tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa
    54901 gaatcatcat cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg
    54961 caccttttac taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg
    55021 tgactgcatt aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca
    55081 tgaaaacggc tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta
    55141 aaaatagaaa ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag
    55201 agagagaaaa taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa
    55261 aatgtacgcg atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca
    55321 gtatatcccg atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca
    55381 aaaaatctgc ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag
    55441 ctaggagaag acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca
    55501 gtagaagcag caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt
    55561 gataccactg accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa
    55621 ggtaaaacag tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta
    55681 tacatcggaa tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact
    55741 ggtttgctgt ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta
    55801 atccctgtaa ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa
    55861 aatgaactga aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa
    55921 gaattggcgc aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct
    55981 gtactgcata cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg
    56041 tattatgtag attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt
    56101 ctctttttct ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt
    56161 ttgataaaat ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt
    56221 aacgaaacga catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc
    56281 aggtttagct gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag
    56341 agaagatcca aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga
    56401 aggagtagga gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa
    56461 agaccgttat aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag
    56521 tgaccagatc ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc
    56581 tgattttatc acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt
    56641 attcgggtta acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac
    56701 agaactattg gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat
    56761 ctacaatcca ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa
    56821 ttggaacaaa ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat
    56881 caatgatttg ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga
    56941 tcaaacaact agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga
    57001 agatcatttc catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca
    57061 gctgatcgag acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca
    57121 agatctgacg tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt
    57181 atccttcttg gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat
    57241 cgggaaccag aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta
    57301 acgatcaatt caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat
    57361 caaaaagata gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt
    57421 actttcgaag tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg
    57481 gaaaacggaa atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca
    57541 atcaaagatg tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc
    57601 aatacagatg atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg
    57661 tatattaaag cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg
    57721 ccaaaagata cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt
    57781 actgaaagca agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat
    57841 cataatggaa cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga
    57901 cacgcttcct ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc
    57961 gacttatgaa caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta
    58021 tgatccaaca ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc
    58081 aactgacgct ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta
    58141 tttgacagaa gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg
    58201 acgtttcgaa cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga
    58261 agaagaccat caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg
    58321 ccgggctgcc tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat
    58381 tatttaatga cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa
    58441 gccggtaaag acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat
    58501 ctggaactga atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa
    58561 tatttagaaa ataatcatga catataagag atagttttgt actttatgat caaaaaagtt
    58621 ttttgtccaa tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt
    58681 ttgatatttt tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt
    58741 gacaaaaaaa caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc
    58801 tgtattcctt gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa
    58861 ttcaatggaa aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat
    58921 cagacgattt gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt
    58981 aatcggtctt ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa
    59041 agtagttaag gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta
    59101 tacgacggac tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta
    59161 ttttgtactt ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa
    59221 taaaactgat attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg
    59281 gatccagtga gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat
    59341 ccaaaatcag tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta
    59401 gcctctaaag ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata
    59461 ttcctgatga atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc
    59521 agccaagaat tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg
    59581 gaaggcaggt ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa
    59641 gccgtgataa gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg
    59701 ttcgacaaca tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc
    59761 atacttaaaa atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag
    59821 atgacatcaa gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc
    59881 aatctaaaaa cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat
    59941 aataaaagga taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact
    60001 ggcatctaac aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat
    60061 tgtacgaata aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt
    60121 tgttataaaa aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg
    60181 tatttccgtc tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat
    60241 ctacttcgtg gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat
    60301 ccgcattttc aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt
    60361 ctttatcttt tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt
    60421 catcccatac cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca
    60481 gcttttcata aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca
    60541 tactattcat ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa
    60601 acgctgtcaa aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa
    60661 aagtgaagat gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt
    60721 ctttataacg ccgattgtaa aattaagcta gacaactaaa aaagtcattt gtgctacact
    60781 caaaatagtt ccgtccaaag aattataagg agtgagtaca aatgacctat acccatctta
    60841 caacggatga acttgtaatg atagagtctt atttcaaaat aaatcaatct gttgcgaaaa
    60901 ctgcgcattt cttgaatcgt tcaagacaaa cgatccataa agtatacctg ttcttcaagc
    60961 aaggaaaatc agccttagag tactatcaac agtataagaa aaacaaatca aactgtggta
    61021 gacgcccgct tgttttacct gaggaacaat cagaatatat tcaaagaaag gttgttcaag
    61081 gatggacacc cgatgtgatt gttggtcgtg cagcgtttcc tattcgttgt tctgctcgta
    61141 ccatttatcg tatgttcaaa aaggggctat ttaatccttc tgacttaccg atgaaaggca
    61201 agcgtaaacc aaatggacat caagaaagac gtggaaaaca agctttccgt cgctctattc
    61261 atgaacgtga aaaagattat agccaattct caaatgagtt tggtcacctt gaaggtgaca
    61321 ctatcgtagg tttgaaacat aaaagtgctg taattacctt agttgagcga ttatcaaaag
    61381 ttatcatcac attgaaaccg tgtggtagac aagcgattga tattgaaaac aaattaaatc
    61441 attggtttga atctgtaccg aaaaatctat tcaaatccat cacttttgat tgtggaaagg
    61501 aattttcaaa ttggaaacag atcagtaatg ccaatgatat tgccatttat ttcgctgatc
    61561 caggaacgcc gtctcaaaga ggcctaaacg agaattctaa cggattgtta cgtagagatg
    61621 gtttattgaa atctatggat ttcaattcag tagatgaatc ttttattcaa tctgtcgcat
    61681 cgaaacgaaa taatattcct agaaaatcac tgaattatcg aacacctttg gaagtatttt
    61741 tgagttacgt aagtattgat gatttgtcta acttaatttg acaattaaga taataaaaaa
    61801 gtgaatttat attgaaaaag aaaaaaacaa gtaaagccgg ggaatattcc ggtatgaaag
    61861 gaatggagag aacaatgacc atccaatggt ttccgggaca tatggcaaaa gcccgacgag
    61921 aagtttctga aaaaatgaaa tatgtggaca tcgtatttga attggtagac gcacgattac
    61981 ctttatcttc tcgtaatcca atgctagatc agatcattca gcaaaaacct cgccttgttt
    62041 tattgaataa agcggatctg gcagatccac aacagacaaa gctgtggcaa gaatattttc
    62101 gtaaacaagg ccatcttgca ttagctatca cggcacaaga aagtaaagga attaaaggtc
    62161 tagtacctgc ggctaaagaa gcattgaaag aaaaacgggc aagagatgct gctcggggga
    62221 tcaagcctcg cgctattcgg gcaatggtct taggtattcc aaatgttggg aaatctacgt
    62281 tgatgaatcg actagtaggc aagaaaattg cacagacagg aaataagcct ggcgtaacaa
    62341 aaggtcagca gtggcttcgt ttaggtaatg agttggaatt gttagacaca ccagggattt
    62401 tatggcccaa atttgaagat gaagaaatcg gcaaaaaact agcgctgaca ggcgcgatca
    62461 aagaccagct tgtccattta gatgatttag cgatttacgg attagacttt tttgcccgat
    62521 attattcagg aagaatcagc gatcgttatg gtttatcaat cgagcaagaa gaaaaattgg
    62581 caccggaatt actgatggat attacagcaa aacgtgggta taaagaagac tatgatcgtg
    62641 gcagcgaatt agtcgtgcat gatattcgtc aaggaaaact tggacgatac acactggatc
    62701 gttgcgaaga aatggagcaa aaaagtgatg actgaatcca tccaaagtat caaagaacga
    62761 ttgaaaagca tacagagaat agatgatcct acactagaat cattaagaaa tgatccacgc
    62821 aaaggcgtgc agcaagcact ggcttctttt gaacgacgat tgaaaaagga agcattaatt
    62881 aaggaaaaat atgaagaaat gttttgcttt gaaaagcaag ggtacgcaca aggtcaccaa
    62941 tggattgccg gcattgatga agtaggaaga ggaccattag ctggacctgt cgtggcagct
    63001 gcagttatct tgccgaaaaa tgagatcata ttagggctga atgactccaa acaattatca
    63061 gagaaaaagc gagaacttct ttatcaacaa gttcaagaaa aagccctggc aatcgggatc
    63121 gggatcgttg atcagcagac aatcgatgat gtgaatattt atgaagcaag taaattagcg
    63181 atgatccaag cagtagaaaa attgtccatt gtaccaagct atttgttgat cgatgcgatg
    63241 accttggatt tgcctattca gcaggaaaaa ataatcaaag gggatgcacg atctgtgtcg
    63301 attgctgctg caagtatcat tgctaaagta tatcgagacc aattgatgaa agaatatgac
    63361 gtgctttatc ctggatatgg tttctcgcat aatgcaggtt atggaacaaa ggaacactta
    63421 gaaggacttg aacgacaagg aattacgcca atccatcgta aaagttttgc acctgtaaaa
    63481 aaatatttac aataaaaaac agccgctttt acgtatctta ttagaaagag agacgaaagg
    63541 cggttttatg atgtatcaaa tagaagaaaa tttattgaaa cttgcttata caaaaggaat
    63601 cagtagtcaa ggaaaatggg cacttgctaa ctggatgatg cagtatcctt ataaagaaat
    63661 cggatttgaa gacatcatta agataggtaa aataaccaaa caccgggagc tgtttcgcaa
    63721 aagttggcag gaaattcacg ctaactgggg caaaatccaa tcgaaacagt cgtttatcac
    63781 ttgctttgat cccaaatatc cccctcagct gcttcacttg acctatccgc caattgtact
    63841 gttttataat ggtgatctat ctttactttc ttgtaacatg ttaagcgttg ttggtggaag
    63901 acacacttct gctttagcca aaaaaacagt ttattattta ctaaaaccag tgatagaagc
    63961 tggatatgtg atcgtcagtg gctgcgcgaa agggatagat acatacggtc accaagcagc
    64021 aatctctcat ggtggacgga caatcgcagt cattggaaca gggatagagc aagtctatcc
    64081 tgctgaaaat cgtgacttgc aagaggtgat tgcaaatgat catcttcttt tgagtgaata
    64141 tcctcctcaa tccggcccga aaaagcattg ttttccaatg agaaatcgga ttatcgcagc
    64201 tttgtctaaa ggaacatgtg tctttgaagc caagaaaaaa agcggctctc tgataacagc
    64261 acagcaagca ttggatcttg gaagaacagt tttttctgtt ccaggaaata ttttaacaga
    64321 acattctacc ggatgtcatc atttgatcca agacggtgca gtttgcacgg tttcgggtga
    64381 agatatcttg gcagaattta aagaataaca ccatactttt catttgcttt tcttgacaaa
    64441 cgttttctga atggatatga ttagctacga tttgtatgaa tcctctttta atagtaggaa
    64501 cacgacaatg gaaaggagtc cattcagtaa tggcgtataa atatttagtg attgtagaat
    64561 cacctgcaaa agccaagaca attgagaaat atcttggacg aaactataaa gtaatggcca
    64621 gtgttggcca tataagagat ttaccgaaaa gtaaaatggg tatcgatttt gaaaacaatt
    64681 atgaacccca ttatatttct atacgcggaa aaggcgatgt catcaaaagc ctgaaagccg
    64741 cagcaaaaaa agctcaaaaa gtttacttgg caagtgaccc ggatagagaa ggagaagcga
    64801 ttgcttggca tttagcgtac ctacttgggt tggatctgaa agaaaaaaat cgggtggtct
    64861 tcaatgaaat cacaaaagac gcagtcaaag cagcttttaa ggaaccaaga acgatcgatg
    64921 tagatttagt agatgcacag caagctcgtc gtaccttaga cagaatcgtt ggttattcga
    64981 tcagtcctat tctctggcgt aaggtcaaga aagggttaag tgcaggacgt gtccaatctg
    65041 tcgctttaaa aattattatt gaccgtgaaa aagagatccg agaatttgtt ccagaagaat
    65101 attggagcat cgacggtaat tttaaaaaag ctcgcaagaa attcaaagca aatttctggg
    65161 gaatcgacgg taagaaaaag aaattaccag atgcacaaag tgtaaaagaa gtcactgcta
    65221 gaattgatgg aacagacttc gaagttaaaa aagtagaaaa gaaagagcgc aaaagaaacc
    65281 ctgcgaatcc tttcactaca agtagcctgc aacaagaagc tgcccgtaag ttaaactttc
    65341 gaacaagaaa aaccatgatg gtagcacagc aattatatga aggaatcact ttgggtaaac
    65401 aaggaacagt cggcttgatt acatacatgc gtactgattc tacccggatt gccgatacag
    65461 caaaagcaga ggccgcagca tttattgaag atacgtatgg aaaagaattt tctagacatg
    65521 gtcaccgaaa gatcaaaaat gctcaaggcg cacaagatgc ccatgaagct gtgcgtccaa
    65581 cgagtgtgct tcgtacacca gatgaactca aacaatattt agataaagat caattgaaac
    65641 tttatacatt gatctggtca cgttttgtgg ctagtcagat gacaccagct attttagata
    65701 caatgaaagt gacattagaa caaaatggtg tcatcttcat tgcgaacggt tcaaaaatca
    65761 aattcaaagg attcatgcaa gtgtatgtgg aaggtagaga tgacggcaaa gaagagaaag
    65821 aaaatattct tccagaactt gaagaaggcg atgtagtcca atctgttgat attgaaccaa
    65881 aacaacattt tactcaacca ccagcacgtt ttagtgaggc tacgttgatt cgtgcactag
    65941 aagaaaacgg ggtagggcga ccttccactt atgcaccaac acttgatacg atccaaagac
    66001 gctactatgt aaaattgaca caaaaaagat ttgagccgac tgaactagga gaaattgtca
    66061 attcattaat ctgtgaattc ttccctcaaa tcgtcgatat ccatttcaca gcagaaatgg
    66121 aaggagattt ggataaaatt gaagaaggca cggaagcgtg ggtcaaagtg gttgatcgtt
    66181 tctataaacc gtttgaaaaa gaactgacga atgcggaaga aaaaatcgaa aaaattcaaa
    66241 tcaaagatga accagcagga ttcgattgtg atgtctgtgg acatccgatg gtgataaaat
    66301 tagggaaata tgggaagttt tatgcttgca gtaattttcc tgattgtcgg aatacgaaac
    66361 caatcgtaaa agaaatcggt gtgacttgcc cagtatgtca tgaaggacaa gtcattgaac
    66421 gaaaatctaa gaaaaacaga ctattctatg gttgttcccg tttcccagaa tgtgaattca
    66481 cttcttggga taaaccagtg ggcagaaatt gtccaaaatg tgacggatat ctggtcgaga
    66541 agaaagtcaa aggcggtaaa caagtagtct gtgtaaatgg agattacgaa gaagacatcc
    66601 aaaaataata gaaaagaggt tctttcattg aaaatggtaa atgttgttgg agcagggctt
    66661 gccggaagtg aagctgcttg gcagatcgca caagcaggag tccctgtccg tttatatgaa
    66721 atgcgtccag tcaaatcgac tgaggcgcat cacacaagta attttgctga actagtatgt
    66781 tccaattcat taagaggaaa cagtttggct aatgcagtag ggttattgaa agaagaaatg
    66841 cgccgattga attcggtagt aatcacttcg gcagatgaaa cagcagtgcc agctggtggt
    66901 gccttagctg ttgaccgcga ttctttttct gaaacaatta cccgaaaagt caaagagcat
    66961 ccattagtaa cagtgataaa cgaagaaatt actgaaatac cggaaggaat caccgtagta
    67021 gcaacaggac ctttgacttc tcatccatta gcagaaagca tcaaagcatt caatggttca
    67081 gatggttttt atttctatga tgcagctgca ccaatcgtag acaaagctac gatcgatatg
    67141 gataaagtat atttgaagtc ccgctatgac aaaggagaag cagcttactt gaactgtccg
    67201 atgacagaag aggaattcaa agctttccat gaggcactaa tcaatgccga agtggcagaa
    67261 cttaaatctt ttgagaaaga aaaatatttt gaaggatgta tgccaattga agtaatggca
    67321 cagcgaggat tcaaaacgat gcttttcgga cctatgaaac cagttggatt ggaagatcct
    67381 aaaactggca aacgtcctta tgctgttatc cagctgcgtc aagacaatgc tgcagcttct
    67441 ttatacaaca tcgtgggctt tcagactcac ttgaaatggg gcgagcaaaa acgtgttttc
    67501 cggatgattc ctgggttaga aaatgctgaa ttcgttcgct atggtgtgat gcaccgaaac
    67561 agctttatga attcgccaga attgctgaaa ccgacttacc aatcaacgaa acgcgaagat
    67621 ctgttctttg caggtcagat gactggtgta gaaggctatg ttgaaagtgc agcgagcgga
    67681 ctacttgctg gaatcaacgc cgcacgctta gcaaaagaaa tggaaccagt cgagtttcca
    67741 caagaaacag ctattggaag tatggcttac tacattactc atgcggaagg aaaacatttc
    67801 caaccgatga atgccaacta tggtctgttt cctgaactgc cagagcgcat tcgagacaaa
    67861 aaagcaagat atgaagcaat tgcacaacga gctttaaaag ctaatgaggc aataaaaaca
    67921 gaattagaaa aaactgcaat cccaaatgag taaggaaact ccatgaagag ggtgagacgg
    67981 atagtctcgc tctttttctt gcgtttttct taagaatttc tcaaacaaaa tgtgaggaat
    68041 tgcgccaatt gtgaacaaac ttagaaatat tggttaaatt ctgacaattt atttgtcttt
    68101 ttataaacgc tgtgctaaat tattctctgg gacaaaagga aggtgagaaa atgacagaag
    68161 ccacgtggga acaaaaattt ttgcgttatt tgattgtcga aagaggatat tcagaaaaaa
    68221 cgaaagaagc atatgaagaa gacattctcc atttcaaaca ttttttggag gaatctggag
    68281 acgctgatct gctgaaggcg gaatatttta cggttcgtgt ctatttgagt gcattagctg
    68341 atcatcgtcc tagctatagc agaaattcta tcagtcgcaa gatagccagc ctacgttcgt
    68401 tttatcagta tcttctcaaa gaagaagtga taaaagaaaa tccattttct tacgttcatc
    68461 tcaaaaagaa aaatttgaga ctgccacgtt ttttttatga aaatgaaatg caagcacttt
    68521 ttgacagcgt agcaggagat agtcctttgg atttgaggaa ccgcgcttta ctggaagtcc
    68581 tttacgggtc aggcatccgt ttaagtgagt gtagcagttt gtcggtatca gacattgatt
    68641 ttgattcaga ggtcatgttg atccatggta aagggaacaa agagagatat gctcctctag
    68701 gttcttttgc tcaagatgct ctgcaagaat atttcaggga aggccgccag gtattgatga
    68761 caaaatatca cgaagagcat gatatcgttt ttgtgaatca tcatggaaaa ccaatcacgc
    68821 ctactggaat tgaatatgtc ttgaatcaaa tgatcaaaaa aagcagtttg gatagtgata
    68881 tccatcctca catgctgcgc catacatttg ctactcattt attaaataat ggggcagatt
    68941 tgcggacagt ccaagaattg ctaggacatg ccaatttatc gactacccag atctatgccc
    69001 atgtaacaaa agaaagttta caaaaaaact atcgttcttt ccatccaaga gcgtaaaaat
    69061 aaggaaaaga acaaatttag gaggaaacaa acatggtcga atcaccattt cattcaacca
    69121 ctatctgtgc cgtcgaaaaa gacgggaaat ttgctatggc tggagatggc caagtaacaa
    69181 tgggtgaatc tgttgtcatg aaaggcactg caaagaaagt acgacgtatc tacaatggag
    69241 aagttgttgt aggtttcgcc ggaagtgttg cagatgcgtt tactttagaa gaaaaatttg
    69301 aaggcaaact aaacgaatat aacgggaatc tacaacgcgc agctgtcgaa ttagctcaag
    69361 aatggcggac acagcaatct atgcaaaaac ttgaagcgat gctgatcgta atgaatgata
    69421 aagaaatgct tcttgtttca ggtacaggag aagttatcac accagatgat ggtatcttag
    69481 ctatcggatc aggagggaat tttgcgttgg ctgcagcccg agcaatgaaa aactatgctc
    69541 aaaacgacat gagtgcgaaa gaaattgcag aaaatgcgtt aaatattgcc gcagatatct
    69601 gtatctttac taatcataat attatcgtag aagaactgta agaggtgagt agatatgtat
    69661 gaattaaaac aaacaccaag acaaatcgta agtgaattag atgaatatat cgtaggacag
    69721 cacgcagcaa aaaaatctgt tgccgttgct ttgcgtaacc gctatcgccg tttgcagtta
    69781 gatgaaaaaa tgcaacaaga tattacacca aaaaatatgc tgatgatcgg acctacaggg
    69841 gtcggtaaaa cagaaatcgc acgacgtttg gcaaaaatcg tcaatgcacc atttgtcaaa
    69901 gtcgaagcaa caaaatttac tgaagtcggt tatgtcggaa gagatgtaga atcaatggtt
    69961 cgggatttag tagaaaatgc gatccaaatc gtagaaaaag agcagtacag ccgtgtatac
    70021 acaagtgcta aaaaaaatgc agaaaaacgt ttggtaaaaa tcttggtacc tggtatcaaa
    70081 aaagaacaga aacaatccac taatcaattt gaacaaatga tgaatctttt taatgctagt
    70141 cagcaaaata ccgctgaacc gcaagaagaa gtgacagaag atattcgaat caatcgccgt
    70201 acagtcttgg aacaactaca aaagggttta ctggatagtc gtgaagtaac cattgaagtt
    70261 gaagaccaaa agaaacctgc accaatgatg aacaatggat tggagcaaat ggggatcgac
    70321 ctaaatgaaa ctctaggtgc tttgacaccg aagaaaaaag tggaacggac ggtaacagtc
    70381 aaagaagctt tagagttatt gatcaaggaa gaatcagcaa aattagtcaa ggatgctgat
    70441 atccatagtg aggcaatcaa attagcggaa gaaagtggaa ttatttttat cgatgaaatc
    70501 gataagatca cttctaaatc acagcaatct ggagaagtat ccagagaagg cgtccaaaga
    70561 gacatattgc caattgtcga aggttcacaa gtaaacacaa aatacgggat catccaaaca
    70621 gatcacgtcc tattcattgc ttcaggagct ttccatttgt ctaaaccaag tgatctaatt
    70681 ccagaacttc aaggacgctt cccgatacgg gtagaattag atgatttgac agctgaagat
    70741 tttgtgaaga ttctgaccga accaaataat gctttagtaa aacaatacgt cgcgttgatc
    70801 ggtacagaaa atgtgtcagt tacgtttaca aaagaagcaa ttgaacggat cgctcaaatc
    70861 gctttcgatg tcaaccgtga cacagataat atcggcgcac gcagactgca taccattttg
    70921 gaaaaactac tagaagatct attatttgaa gcaccagata tgcaaatggg agaaataacg
    70981 atcacagaag catatgtgga tgacaaactt ggctcaattg cggcaaatga agatttaagt
    71041 cgctatattt tataaaaaat cggaggacga caatgacaga cttgctaacg aaaacccgca
    71101 agataaacac acttttgcag caaaagaata cttttgacat gcaagcagat ttgccttacg
    71161 ataaaatggc tgtcacacta ggtggtattc ttgacagcaa cacctatatc ataggaagtg
    71221 acggagtatt actaggttat aatgaacgtc acgatgtgaa caatgaacga atcaaaacaa
    71281 tgtttgttga gaaacaattt cctgaatctt atactgatac agtggcacag ttgatgaaaa
    71341 ctgaagctaa tatcccaatt actagtgata ttactgcatt tccggtagag tcaagagaga
    71401 aatatccatt tggtctgacg actgtcgttc cgatctttgg agctggcgaa cgtttgggta
    71461 cgattatctt atctcgtatg gaacaatcgt ttgcagatga cgatctagtc ttagcagaat
    71521 atggagctac ggttgtcggt atgcagatcc tttatcagaa gtctcgaagc atcgaagcag
    71581 atgtacggag tgcaacggct gtccaaatgg caatcaacac attatcttat agcgaattga
    71641 aggctgtaca agctatcttt gaagcattgg atggagatga aggtcgtctg actgcttcta
    71701 atattgccga tagtatcggc atcactcgtt ctgtgatcgt caatgcttta cgaaaattgg
    71761 aatcagctgg aatcattgaa tctcgttcgt taggcatgaa gggaacttat ttaaaagtat
    71821 tgaattcccg ttttaaagac gagttagcaa aacacagtta ttagaagtaa ggggactggg
    71881 gcagatagaa atgtttgttc cagccttccc attttaaaaa gtaagtcgaa gttggaggaa
    71941 tggcaatgac tgttattatt caaaatgacc agctgatcgc cgaaatcgct gaacacggtg
    72001 cggaattgat cagtctgaaa tcaaaagaac atggtttaga gtatatctgg caaggtgatc
    72061 cagcgtattg gggcagacat gcaccggttt tattcccttt tgttggacgt ttaaaagatg
    72121 atcagtatgt ttatcaaggg aaaacatatc aaatggggca acacggattt gctcgggata
    72181 tggattttga agtcattgaa catggacaag aaatggctag tttcatctta aggagtacgc
    72241 cggagacatt agaaaagtat ccatttgatt ttgaattagt gatcagctat gaattaggag
    72301 gagacggcat cacggttcat tatcaagtgg caaataccgg tgaaaaagaa atgttctttt
    72361 ctatcggtgg acatcctgct ttcaatgtac ctcttgaaga aggattgtca tttgaagatt
    72421 tctatctggc attttctcca ttgaaatcaa gattacgcct accattgaaa ggcccattca
    72481 tcgatatgga tcaaaagacg ttaggtcaga caaatacgaa tctggctttg aatcgtgaac
    72541 tttttgagca agatgccttg gtttttgaaa caaggggtct aaatgcgtac gccattcgaa
    72601 gtgaaaaatc ttcccatagc gtaactttaa gctataaaga tatgccttat gtagggatct
    72661 ggtctcctta tccaaaagaa gcgcctttcg tttgtatcga accgtggtgc ggaatcgctg
    72721 acacggtgaa cagtagtgga aacttgatgg aaaaagtagg gatcaatcaa ctaggtgccc
    72781 atgaaatctt caagacaaaa tattccatca cagtgaagta agaggttgtg accgagaagt
    72841 tagcagggaa caccgtttac caaggtgtgt aaaaaagcta tcctgtaagt aataagggag
    72901 tgtgacatcg atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt
    72961 ttttcttgct gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct
    73021 tgatattgtc tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca
    73081 gtaaccaatt gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata
    73141 aagtgatcaa tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac
    73201 taacgataaa gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc
    73261 ctgcacttgt cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc
    73321 caagaatggc gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg
    73381 gcaaacaagt agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg
    73441 ttttgcctaa tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga
    73501 tatctttttt gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat
    73561 atgctaaaat aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat
    73621 cctttatttt agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata
    73681 atagatggaa taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca
    73741 agaaacgatt ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa
    73801 taaaccagaa cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat
    73861 cataccagta aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa
    73921 tttgacagaa atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt
    73981 acctgaaata gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg
    74041 gattgaaaac aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat
    74101 ggatcgttgt attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc
    74161 acaaagaaga gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa
    74221 ttgatttctc gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc
    74281 ggttttgccg caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga
    74341 atacaatgac tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg
    74401 gatgtacatt ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga
    74461 taatgcagtt gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga
    74521 agacaatagt ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc
    74581 cggaatacca acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca
    74641 aggagggtac aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt
    74701 atcgaaatgg ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa
    74761 aaacggcggt aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg
    74821 gacgactgtc cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga
    74881 aattttagcc gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct
    74941 ttctgatctt cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa
    75001 agaatttgtt gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc
    75061 aggagaaaaa gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga
    75121 aaatgtttta tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg
    75181 tatgaaagcg gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa
    75241 agaacgggac aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc
    75301 tatccgtgta cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac
    75361 gccagttgct cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca
    75421 ggaaaatagc gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag
    75481 agaagcagca cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga
    75541 atctcttctt tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt
    75601 gtatttagtc gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt
    75661 ccaagcaatt ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga
    75721 tatcttgaaa aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc
    75781 tgagttttct atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac
    75841 agacggcgcc catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct
    75901 gattgaagct gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca
    75961 aggaaagaag caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa
    76021 aaaagtcggc aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga
    76081 acaattgtgg gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga
    76141 tgatgctgcg caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg
    76201 aagaaaatgg atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga
    76261 taaaaaagag gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg
    76321 agcagataaa aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa
    76381 aatcgacaag aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt
    76441 tattccaaat atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca
    76501 gtgcaacgcc ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc
    76561 cgtaaatcag caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgacatc
    76621 agtatttatg aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc
    76681 gaaatgcacg ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact
    76741 gaagccagat tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc
    76801 gatctcgtgt ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac
    76861 ccaaaccttc tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg
    76921 actcataact tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg
    76981 agccttgaaa aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg
    77041 caaggaaaag atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt
    77101 tcgaaaacaa agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc
    77161 ccatatgaag taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag
    77221 aaaatcgatg gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc
    77281 gtcgaattga aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact
    77341 gagctacaga tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa
    77401 gttggactga aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa
    77461 cgtagtcaat tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg
    77521 aaagctttat cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa
    77581 gacgccaaaa agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt
    77641 gtcacattgc aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc
    77701 gaaagcttga ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt
    77761 ttctctgtta tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta
    77821 acgacaatcg aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa
    77881 gaagacgtaa ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct
    77941 tatagtgctt ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca
    78001 ggtgaattga gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac
    78061 cgccctgtcc atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa
    78121 acaatctcca atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt
    78181 caagcagaga aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg
    78241 acagagttcg aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag
    78301 gcggaagaag atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt
    78361 ttcttagtaa cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt
    78421 ggagcaaagg cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac
    78481 gggctgcttg tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct
    78541 gttaaacgca tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg
    78601 gtcatgcgtg agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca
    78661 aaagaaataa ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc
    78721 cctataggtg atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa
    78781 gtcatcgaag ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt
    78841 aatgaagaga cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata
    78901 aatccttata cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt
    78961 caacgttgat ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa
    79021 acccttgcaa agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca
    79081 gaaatttagg aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa
    79141 gaaggcgtag acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac
    79201 agctttttgg aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta
    79261 aatgatatcc aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact
    79321 attacttcac acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag
    79381 acagacaaac ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat
    79441 gcgctaaaaa gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg
    79501 cgcaaaacac ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt
    79561 aaaaacaaaa tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac
    79621 tatcgtcgtg tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat
    79681 gatatgactg gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact
    79741 gaacaatatc gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt
    79801 tctaaaccag ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca
    79861 gcaatcaaat cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat
    79921 atctatatcc aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg
    79981 atcgaccact tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac
    80041 caattattct caggattccc tatctgggct actttatcca ttgcaggtat gggattagat
    80101 ggtcgttcat tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga
    80161 ccttcaccag aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga
    80221 acatatgcta gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag
    80281 cttcgtgaac aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt
    80341 gtcggaaaag acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat
    80401 gccatcaatg gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca
    80461 atcacatcag aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat
    80521 tggttagcag aactatatgt caatacgttg aacatcattc attatatgca tgataaatat
    80581 tcttatgaag cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca
    80641 ggtattgctg ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta
    80701 aaagcaatcc gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct
    80761 aaatacggaa atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc
    80821 atgggacaaa tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg
    80881 acgattactt caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa
    80941 gctggaaaac cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta
    81001 ttagctagcc tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca
    81061 aatacccaaa caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac
    81121 ttgcgtaatg tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta
    81181 ttcagtaatg atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg
    81241 atccgggtat ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat
    81301 gtcttgatga gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact
    81361 tagcgtcgaa aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt
    81421 tgaaagaaac gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat
    81481 aacgaagcgg caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt
    81541 acttaaaatg aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat
    81601 gttcattcta tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt
    81661 atgcaaggat gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc
    81721 ggagggaaag aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac
    81781 tggggagata aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt
    81841 ttgatcgaac tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc
    81901 ggaaaacctt ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat
    81961 acagatttac tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg
    82021 cattgggaca atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg
    82081 gtttggattc gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga
    82141 ctagacaact ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat
    82201 acgatgggaa aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa
    82261 ccacctacaa aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca
    82321 aaatatttaa cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt
    82381 ttgctattat taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt
    82441 tttggtcacc aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg
    82501 caaaatgaat taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca
    82561 caatacgcat tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca
    82621 gaaaatgcag atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc
    82681 agcgaagtaa atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct
    82741 aatccattgt actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta
    82801 tataaagaaa accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc
    82861 atttcagata cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca
    82921 aaagaacttg cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa
    82981 gcaggaacaa atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt
    83041 ttcccaatgg gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa
    83101 gtgatggatc gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc
    83161 tacgatctgt tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt
    83221 gctggtaaag gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt
    83281 gctttgctta aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta
    83341 tttagctaat caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa
    83401 aaagaaacat agaacatact aaaggccgaa gaaatggagg agaataacag tcaattatga
    83461 ctcttgttct tcctcctttt tacgtaaaag ccttttaagt aaaataaaac ggatagaaaa
    83521 gagaacatat atgaactatt attcaaaaaa taaggaaaac ttttatcaaa aactgaccga
    83581 tgatccgctt ttttcttcat tgaccgatta tctatatgaa catcgagaac aagaaacgat
    83641 tctaagagaa ttgaaaaaag aattttcgca aaataaattt tcccattttc ttgatttatt
    83701 gatcgatgca ggattaatca agagggaaga acgaagatat catttgaact ttccaatatt
    83761 tgatcctaaa gattacttgc aacaagccac ttcggctgct gaaaccatag ctgaacaatt
    83821 gaagagactc tctgttgatg aacaaaaatt agcgatggga gaagttattt gggcgtattg
    83881 tttcgaagat gaacggaaag aagcgtattt ttatggagta agaaacagcc gagagacaga
    83941 attgctgagg acaactgcag gaaatgagaa gtaccgtttt atcacacttt cctctataga
    84001 acacttcccg cttactttgg ctaattactt ttttgtacag aagaatcagc ttcctgtaac
    84061 gaaggcattc aaagaattag ccgaacttat tggagacgta aatgaatcgt acttttttga
    84121 tcaaatagaa gttatcgttg acaggatacg taagaataaa tataaaaatc gccggcctag
    84181 tattttccat cagtctctac ttgtgacgaa tactataaag gaagaagaat cattcacatt
    84241 agaattacct attgtcgaaa aaaacaattt tgagattgaa ttaccaacat tggatccttc
    84301 attgacaatg gaggaaatgg cctttcttaa acgacaaatc ttttctgagc tgagcaagaa
    84361 atttataccg catgcatttt cttatatcaa agaatatgga acagttttag tgagtaaaac
    84421 ctaagagagc agtaagcaaa aattatactg actcttgcag gaggagcctt tctcttcctt
    84481 tatggttaaa agaattattt gagtattttg cctatctacc acctattaga ttcactacat
    84541 ggtctggaaa caaaggaatg caaaaaaatg gtgagaaatg tggaatgaca aaggaagtag
    84601 tgataagaaa agttagattt ttaaataatc aatattatga ttcagtcaag tatggcattt
    84661 tatgggaaga actagctgat tagattagga agtccatttg ataatccaga atcactaaga
    84721 aacgaatggc gagtcattaa taatttatcc aatcttgggt tattctttta gattgaagtg
    84781 tttaaaacta aaaaagcatt tatgaagtcg taatagtcag gcttcaaaat gctttttatt
    84841 ttgtttgttt tttctttgcc acataaatac acctagactg acgatgaaga gcatatccaa
    84901 cagatttcct gcgacttgga tcgtcgaagg gttggtcagt ggcattaaag caaggacaaa
    84961 aaaggaaaac aagctgtaaa taaaacaggt gacaggaact aatcgaaaga agagcggaca
    85021 tttcaattgg ctaaaaatga gtgaaaaaat aaaataagta aaaatggata aaatcacgac
    85081 taaaccattc atgataaaga agaaaagcgt attgtgatta aacgaataaa aaagaattgc
    85141 taaaaaagaa aacgttttaa atgcaatcaa tacgcttgaa gcttcgttta acgtaccagg
    85201 atgtcgatga aaaaaatagg caccgaaata aacagaaaac agtaagccgc aaagagaaga
    85261 caaaatcaaa aaaaacggat tttcttcggc ttctgtgata tcagaatgat ccaaaagcaa
    85321 ccagcctaat gcactagaag gcgcatgtga ggtcttaagg tatgaataac atagaaaaaa
    85381 taagatcgtc aaagttgcaa aaaaagagcc taaatgtaaa aaattagtgg ttctacgttg
    85441 aatttccata atatctccaa attaaattga taagtatata aagtataata acaaattgat
    85501 gagtatatgt cgatgttttt taatcaaaat aataaataaa aactgtctaa catttaaaat
    85561 ttaatttaga tattagacag tttttaagtt tgtgagttat tttccttgtc gttttctcac
    85621 ttttttagtc cagaaaccac ctgaaatata ttttggctca taagaaatga taaaagcacg
    85681 ctcttcgatt tctttgatca ggcgatacag ttcacgttcg ctttttctag gagaaagtat
    85741 ttcgagaact agccgctcac cttccagccc cattgcagaa gtctgtgtca caccataacc
    85801 gtgttctctc agtatacccg gcaaactttt atcttctgcg ctatttgctg gcaaaatcgt
    85861 tgtgaccatg atgtatccta atgccaattt gtcttcaatc aaaattccga cactgatacc
    85921 tactgcgtaa cctaacgcat agacaaataa attcagtgga ttatctaaac gatctaaaac
    85981 aagggataag ccgacgatat aaatcgtgat ctcgaccata ctgacaagtg gagcaatcag
    86041 tcgatagcct ttcattgtca acatgaaacg taacgtgttc agagtgatat aagcaaaatt
    86101 aatgaggaag atcatcccca acatttttgg atcaatcatt tgtaaaactc ctttcattta
    86161 tataacaaca atatcaaaaa aaatcgtaag tgaagaaaaa ttgaaacttt atacatacaa
    86221 aaaaatgata aaatgattat aatagaatta taaagatagg ttaggtgatt aaaatgaaaa
    86281 cggtcaatcg tgtgttttgt gccagccacg tgctaagtct ccttctcagt atatacttag
    86341 gtgtctattc gattcaacag ccaattgagg tagagaacat tgtttttcag atgtcgctga
    86401 cagatggttt aattttaagc gtttttttct ttttgatact gtttattggt aatattttcg
    86461 gtagcgttgc cagttttttg aatttttcta tttatccact cctttcgcta gcattaggag
    86521 tggtgggact ttgttctctg tgcttatttc ccgagccatt cagtcctgca tttatattat
    86581 ttggtacact gaacctgttc cagacaactg ttggagcatg gttgctatgg cgatcaggaa
    86641 atttaatgaa aataggtgag taacaattga atccaattat attgaaacgt tctgtccatc
    86701 atattccagt gttagaagtt gttctgaaag aattaagaga ggaacgtatt cccgttgtca
    86761 tctattatca cggatggcag acaagtaagg agttagtttt gacgcaagga agaaaaattg
    86821 cgcagcaggg cattcgtgtg atcctgccag atgcgatgaa tcatggggag cgcaaacagc
    86881 cggtttcttc tattccatcc tatacatttt gggatagtat ctacggaaat ctgtttgaat
    86941 ttgacacact tatcaagcat ttagaaaaaa gaggtcttct acatgatcag cttgcagttg
    87001 gcggggtttc gatgggggga atgacaacat gcgccttgtt ggctaaacat cctcatatag
    87061 tagcgggcgt gtgtttgatg ggttcccctg cacctttgga atatggaaaa gaaatcgtaa
    87121 ggcgcgcatc ggaatataat tatgtcgtac caaaagacta ttttgatttg atttcatggg
    87181 ttaagagcta tgatttgtca ttgcagccgg aaaagttagc tggacgtcct ctgttctttt
    87241 ggcatggaca agctgacgaa aaaatccctt atatacaaac ggaacgattt gtagaaaaaa
    87301 atcggcataa gtcttacgga aaagaaattg tttttcgttc ctcaaaaaca cagcgacata
    87361 tggtacaaat accactaatg gaagaagctt ccactttttt agcaaaaaat ttgataaaaa
    87421 agtataaata attgaaacgg aaaatcactc atgacgatag aggattttcc gttttttatt
    87481 ttgggctata ataaactctg ttaggaaaat ttggtataat tgatagtaag aatgacaaca
    87541 tgttagaaag gaagagagca tgcccacttt agcagatgtt gcaaaacgtg ccaatgtttc
    87601 aaaaatgacg gtctctcgag tcatcaatca tccggaacag gtgactgacg aattgaaaga
    87661 gttagttttc tcagcaatgg ctgaactgga ttaccgtcca aatattgctg caaaagcact
    87721 tgtcacgaat cggtcgcaga tcatcaaatt atttatactg gaagaaatcg acacaactga
    87781 gccctattac atgaatttgc tgatgggaat cgctaaacgg atcggtaaag cgcattattc
    87841 tctccaatta gttacaaatg atgccttcga cgtcggttct tgtgatggat acatcatcac
    87901 aggtgtcaga aaaaaagact tcgattggat cgaccgtttg gaaaaaccag ttgtcttgtt
    87961 tggggaaaat tctgaaggat atgattatgt agacagcgat aatgaatatg gtacagcaaa
    88021 agcaacgcaa tatgccttag aaagagatta tcaaacgatt atttatatcg gtatcgaagt
    88081 ggacgagcct tttgaaattt caagggaaac tggttattta tctgtgatga aggaagttga
    88141 tcttcctagt aaaatcttgc ggtttccaaa tcattcgaca gaagtagaaa gatatatgac
    88201 agaaaactgg gcagatttta cagataaaac ttgttttgta tgtagttcag atcggctagc
    88261 actaggagca gtaagaggga ttataaatgc tggaggacac ttgcccgaag aatttggtgt
    88321 gattggattt gatggggtat ttttagacca aatcagttca cctaaattga caacgatcaa
    88381 gcaagatatt atacgtatgg gtgaagtatg tggagaaatg ttgttaaaaa aaatagaaga
    88441 aaaaggggcg agtcaaggtt atcgtcgttt ttttcctgaa ctagttatca gagagacaac
    88501 gaattaagtc ttattactat atatatat
//
LOCUS       DAXLPQ010000007        79036 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.007, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000007 DAXLPQ010000000
VERSION     DAXLPQ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 79036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.007"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..1073
                     /locus_tag="ACF3UO_000616"
     CDS             <1..1073
                     /locus_tag="ACF3UO_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656668.1"
                     /translation="VFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFS
                     LLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRY
                     NYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKP
                     FFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNG
                     NKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTS
                     IFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKN
                     EFMQFGLTVLGICTFIITVINR"
     gene            complement(1313..1396)
                     /locus_tag="ACF3UO_000617"
     tRNA            complement(1313..1396)
                     /locus_tag="ACF3UO_000617"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1360..1362),aa:Leu,seq:gag)
     gene            1469..1630
                     /locus_tag="ACF3UO_000618"
     CDS             1469..1630
                     /locus_tag="ACF3UO_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656669.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            1779..2996
                     /locus_tag="ACF3UO_000619"
     CDS             1779..2996
                     /locus_tag="ACF3UO_000619"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3656670.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3180..4016
                     /locus_tag="ACF3UO_000620"
     CDS             3180..4016
                     /locus_tag="ACF3UO_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656671.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            4092..5240
                     /gene="nagA"
                     /locus_tag="ACF3UO_000621"
     CDS             4092..5240
                     /gene="nagA"
                     /locus_tag="ACF3UO_000621"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFD3656672.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            5518..6519
                     /locus_tag="ACF3UO_000622"
     CDS             5518..6519
                     /locus_tag="ACF3UO_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFD3656673.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            6538..7557
                     /locus_tag="ACF3UO_000623"
     CDS             6538..7557
                     /locus_tag="ACF3UO_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFD3656674.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(7659..8375)
                     /locus_tag="ACF3UO_000624"
     CDS             complement(7659..8375)
                     /locus_tag="ACF3UO_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3656675.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(8344..9129)
                     /locus_tag="ACF3UO_000625"
     CDS             complement(8344..9129)
                     /locus_tag="ACF3UO_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3656676.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(9120..9869)
                     /locus_tag="ACF3UO_000626"
     CDS             complement(9120..9869)
                     /locus_tag="ACF3UO_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFD3656677.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            10167..10691
                     /locus_tag="ACF3UO_000627"
     CDS             10167..10691
                     /locus_tag="ACF3UO_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFD3656678.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10707..12206
                     /locus_tag="ACF3UO_000628"
     CDS             10707..12206
                     /locus_tag="ACF3UO_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFD3656679.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(12294..12896)
                     /locus_tag="ACF3UO_000629"
     CDS             complement(12294..12896)
                     /locus_tag="ACF3UO_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3656680.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            13000..13956
                     /locus_tag="ACF3UO_000630"
     CDS             13000..13956
                     /locus_tag="ACF3UO_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFD3656681.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(14261..15217)
                     /locus_tag="ACF3UO_000631"
     CDS             complement(14261..15217)
                     /locus_tag="ACF3UO_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HFD3656682.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITINKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            15391..15951
                     /locus_tag="ACF3UO_000632"
     CDS             15391..15951
                     /locus_tag="ACF3UO_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656683.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15944..16768
                     /locus_tag="ACF3UO_000633"
     CDS             15944..16768
                     /locus_tag="ACF3UO_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFD3656684.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16778..17395
                     /locus_tag="ACF3UO_000634"
     CDS             16778..17395
                     /locus_tag="ACF3UO_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3656685.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            17413..18096
                     /locus_tag="ACF3UO_000635"
     CDS             17413..18096
                     /locus_tag="ACF3UO_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFD3656686.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18779..20062
                     /locus_tag="ACF3UO_000636"
     CDS             18779..20062
                     /locus_tag="ACF3UO_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3656687.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            20078..20965
                     /locus_tag="ACF3UO_000637"
     CDS             20078..20965
                     /locus_tag="ACF3UO_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3656688.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20982..21818
                     /locus_tag="ACF3UO_000638"
     CDS             20982..21818
                     /locus_tag="ACF3UO_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3656689.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21821..22444
                     /locus_tag="ACF3UO_000639"
     CDS             21821..22444
                     /locus_tag="ACF3UO_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656690.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            22441..23733
                     /locus_tag="ACF3UO_000640"
     CDS             22441..23733
                     /locus_tag="ACF3UO_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3656691.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGNVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      24092..24189
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24305..24886
                     /locus_tag="ACF3UO_000641"
     CDS             24305..24886
                     /locus_tag="ACF3UO_000641"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFD3656692.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24889..26196
                     /locus_tag="ACF3UO_000642"
     CDS             24889..26196
                     /locus_tag="ACF3UO_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFD3656693.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26612..27100
                     /gene="purE"
                     /locus_tag="ACF3UO_000643"
     CDS             26612..27100
                     /gene="purE"
                     /locus_tag="ACF3UO_000643"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFD3656694.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            27093..28217
                     /gene="purK"
                     /locus_tag="ACF3UO_000644"
     CDS             27093..28217
                     /gene="purK"
                     /locus_tag="ACF3UO_000644"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFD3656695.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            28230..29525
                     /gene="purB"
                     /locus_tag="ACF3UO_000645"
     CDS             28230..29525
                     /gene="purB"
                     /locus_tag="ACF3UO_000645"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFD3656696.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29705..30082)
                     /locus_tag="ACF3UO_000646"
     CDS             complement(29705..30082)
                     /locus_tag="ACF3UO_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656697.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            30338..31066
                     /gene="purC"
                     /locus_tag="ACF3UO_000647"
     CDS             30338..31066
                     /gene="purC"
                     /locus_tag="ACF3UO_000647"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFD3656698.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            31066..31320
                     /gene="purS"
                     /locus_tag="ACF3UO_000648"
     CDS             31066..31320
                     /gene="purS"
                     /locus_tag="ACF3UO_000648"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFD3656699.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            31322..31993
                     /gene="purQ"
                     /locus_tag="ACF3UO_000649"
     CDS             31322..31993
                     /gene="purQ"
                     /locus_tag="ACF3UO_000649"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFD3656700.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31994..34216
                     /gene="purL"
                     /locus_tag="ACF3UO_000650"
     CDS             31994..34216
                     /gene="purL"
                     /locus_tag="ACF3UO_000650"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFD3656701.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            34201..35640
                     /gene="purF"
                     /locus_tag="ACF3UO_000651"
     CDS             34201..35640
                     /gene="purF"
                     /locus_tag="ACF3UO_000651"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFD3656702.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETNFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35663..36715
                     /gene="purM"
                     /locus_tag="ACF3UO_000652"
     CDS             35663..36715
                     /gene="purM"
                     /locus_tag="ACF3UO_000652"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFD3656703.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36712..37290
                     /gene="purN"
                     /locus_tag="ACF3UO_000653"
     CDS             36712..37290
                     /gene="purN"
                     /locus_tag="ACF3UO_000653"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFD3656704.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            37287..38822
                     /gene="purH"
                     /locus_tag="ACF3UO_000654"
     CDS             37287..38822
                     /gene="purH"
                     /locus_tag="ACF3UO_000654"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFD3656705.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38838..40112
                     /gene="purD"
                     /locus_tag="ACF3UO_000655"
     CDS             38838..40112
                     /gene="purD"
                     /locus_tag="ACF3UO_000655"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFD3656706.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            40234..41148
                     /locus_tag="ACF3UO_000656"
     CDS             40234..41148
                     /locus_tag="ACF3UO_000656"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFD3656707.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(41281..42846)
                     /locus_tag="ACF3UO_000657"
     CDS             complement(41281..42846)
                     /locus_tag="ACF3UO_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656708.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42839..44290)
                     /locus_tag="ACF3UO_000658"
     CDS             complement(42839..44290)
                     /locus_tag="ACF3UO_000658"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3656709.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(44304..45320)
                     /locus_tag="ACF3UO_000659"
     CDS             complement(44304..45320)
                     /locus_tag="ACF3UO_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3656710.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45540..46628
                     /gene="chvE"
                     /locus_tag="ACF3UO_000660"
     CDS             45540..46628
                     /gene="chvE"
                     /locus_tag="ACF3UO_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3656711.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46682..48208
                     /gene="mmsA"
                     /locus_tag="ACF3UO_000661"
     CDS             46682..48208
                     /gene="mmsA"
                     /locus_tag="ACF3UO_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3656712.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            48210..49415
                     /gene="mmsB"
                     /locus_tag="ACF3UO_000662"
     CDS             48210..49415
                     /gene="mmsB"
                     /locus_tag="ACF3UO_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFD3656713.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49672..50649
                     /gene="guaC"
                     /locus_tag="ACF3UO_000663"
     CDS             49672..50649
                     /gene="guaC"
                     /locus_tag="ACF3UO_000663"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFD3656714.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50913..52337
                     /locus_tag="ACF3UO_000664"
     CDS             50913..52337
                     /locus_tag="ACF3UO_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFD3656715.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(52379..52636)
                     /locus_tag="ACF3UO_000665"
     CDS             complement(52379..52636)
                     /locus_tag="ACF3UO_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656716.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            52798..53907
                     /gene="pdhA"
                     /locus_tag="ACF3UO_000666"
     CDS             52798..53907
                     /gene="pdhA"
                     /locus_tag="ACF3UO_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFD3656717.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53910..54887
                     /locus_tag="ACF3UO_000667"
     CDS             53910..54887
                     /locus_tag="ACF3UO_000667"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFD3656718.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54912..56555
                     /locus_tag="ACF3UO_000668"
     CDS             54912..56555
                     /locus_tag="ACF3UO_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFD3656719.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56563..57969
                     /gene="lpdA"
                     /locus_tag="ACF3UO_000669"
     CDS             56563..57969
                     /gene="lpdA"
                     /locus_tag="ACF3UO_000669"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFD3656720.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            58131..58406
                     /locus_tag="ACF3UO_000670"
     CDS             58131..58406
                     /locus_tag="ACF3UO_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFD3656721.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            58412..59179
                     /locus_tag="ACF3UO_000671"
     CDS             58412..59179
                     /locus_tag="ACF3UO_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFD3656722.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            59347..61176
                     /gene="typA"
                     /locus_tag="ACF3UO_000672"
     CDS             59347..61176
                     /gene="typA"
                     /locus_tag="ACF3UO_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFD3656723.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            61437..63209
                     /gene="recQ"
                     /locus_tag="ACF3UO_000673"
     CDS             61437..63209
                     /gene="recQ"
                     /locus_tag="ACF3UO_000673"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFD3656724.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            63323..63625
                     /locus_tag="ACF3UO_000674"
     CDS             63323..63625
                     /locus_tag="ACF3UO_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFD3656725.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63628..64791
                     /locus_tag="ACF3UO_000675"
     CDS             63628..64791
                     /locus_tag="ACF3UO_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFD3656726.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64817..68245
                     /locus_tag="ACF3UO_000676"
     CDS             64817..68245
                     /locus_tag="ACF3UO_000676"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFD3656727.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            68266..69390
                     /locus_tag="ACF3UO_000677"
     CDS             68266..69390
                     /locus_tag="ACF3UO_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFD3656728.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            69371..69817
                     /locus_tag="ACF3UO_000678"
     CDS             69371..69817
                     /locus_tag="ACF3UO_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3656729.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69801..70139
                     /locus_tag="ACF3UO_000679"
     CDS             69801..70139
                     /locus_tag="ACF3UO_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFD3656730.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            70258..70818
                     /gene="rsmD"
                     /locus_tag="ACF3UO_000680"
     CDS             70258..70818
                     /gene="rsmD"
                     /locus_tag="ACF3UO_000680"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFD3656731.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70815..71306
                     /gene="coaD"
                     /locus_tag="ACF3UO_000681"
     CDS             70815..71306
                     /gene="coaD"
                     /locus_tag="ACF3UO_000681"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFD3656732.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            71296..72339
                     /locus_tag="ACF3UO_000682"
     CDS             71296..72339
                     /locus_tag="ACF3UO_000682"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFD3656733.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72498..73226
                     /locus_tag="ACF3UO_000683"
     CDS             72498..73226
                     /locus_tag="ACF3UO_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFD3656734.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            73342..73587
                     /locus_tag="ACF3UO_000684"
     CDS             73342..73587
                     /locus_tag="ACF3UO_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3656735.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73584..73802
                     /locus_tag="ACF3UO_000685"
     CDS             73584..73802
                     /locus_tag="ACF3UO_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFD3656736.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73938..74477
                     /locus_tag="ACF3UO_000686"
     CDS             73938..74477
                     /locus_tag="ACF3UO_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFD3656737.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            74470..76743
                     /locus_tag="ACF3UO_000687"
     CDS             74470..76743
                     /locus_tag="ACF3UO_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFD3656738.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            76781..77827
                     /gene="holA"
                     /locus_tag="ACF3UO_000688"
     CDS             76781..77827
                     /gene="holA"
                     /locus_tag="ACF3UO_000688"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFD3656739.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77916..78170)
                     /gene="rpsT"
                     /locus_tag="ACF3UO_000689"
     CDS             complement(77916..78170)
                     /gene="rpsT"
                     /locus_tag="ACF3UO_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFD3656740.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78570..78839)
                     /locus_tag="ACF3UO_000690"
     CDS             complement(78570..78839)
                     /locus_tag="ACF3UO_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656741.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
BASE COUNT        25630 a        13497 c        17199 g        22710 t
ORIGIN      
        1 atgtttttga gaaaataaat gttaaaaatt tattattggt ttgctctata tactgtttaa
       61 taccattgac agtaatgggg gaaaccggtt ggagagcaac caccttgaac tatcagtggc
      121 cagtagcatt tagtttacta actttttatc cgttttttca actcttaaga ggagaagaaa
      181 taaatagaaa aatatattgg gtaagtattc ctttattgat atttttaact aatcaagaac
      241 aagtcaacgc ctgttttttt gttctaacaa gtatagttag tttatatttg attgtcaatg
      301 gacgatataa ttataagtta tcagtatttt caataataag cttagcagaa ttaattttct
      361 ctttgacaac tccagggaat gcattacgtg ctgcacatga aattaataaa tggtttcctg
      421 aatataaaaa tttcaacttt cttaataagt tagatttagg tatttcatca tttggaaagc
      481 cgtttttttt agacatgaat atcttatttt tattgctatt tttcttaatt ttccttctaa
      541 catataggaa atgtcaaaac tattatgtgc gtatattgac tgcattaccg tttttcttaa
      601 acctgattat ttattttggt aatacaatgg gtcaaagctt tacttacgtc aatggaaata
      661 aaagggcaat gatttggagt agtagtaacc tgaataatct ctttacagag ttaggaacga
      721 aactgtcact tttttatcca ggtacttgga tagctacttt agtagtcttg gcattattac
      781 tatgtttaat tgttggaatt tatttaagtt ttgacaataa gaaaacttct atttttttag
      841 ttattttgat gataatggga ttttgttcaa ggttaattat gggattttct cccacagtat
      901 gggcttccgg aatgcggacg tactatatac tttatgttgt tatcgccatc ttagtactaa
      961 tggcagttaa agagctaatg aaaagcatga gtgtacaaaa aaatgaattt atgcaatttg
     1021 gattaaccgt gcttggtatt tgtaccttta taataacggt gataaacaga taatatacaa
     1081 aaaatccctc gctttagtat taggtgaggg attttactcg tttttcgatt aattgtttta
     1141 acacttgcaa gtttctacga gtagcttgtt tccgaccttc atatactcac ctcaggctgt
     1201 ttacatgatt gtacgttctt tttgtaaagg atacagtgat atgtatataa tggcataaag
     1261 aaacgttcaa acaaaaaaac tcgtgaagca aaattaactt cacgagttgt agtgcagatg
     1321 atgggactcg aacccacacg agctaacgct cacatgaccc tcaatcatgc ttgtctgcca
     1381 attccaacac atctgcgtaa taataacaca ctaatgatag cgaggtttta catagttgtc
     1441 aagctcaaaa atgggaggac ttattaagat ggagaaatat gacggagaat tttcaggact
     1501 gggaatgatc ttaggtgtat tgattggact tgcattcgga cgttttttgc ttggttttat
     1561 gctaggaatc atttgtggaa ttgcaatgga ttgggcagcg aatctatgga atgactatca
     1621 tgacaattaa gttctcaacg cttgtttgtg tttttttaat acttacgttt ttcctaaata
     1681 agtggcaaaa ttttctagga tggagtatga tattgaaata gtaaataaca aaaaatttgg
     1741 aaagttctaa ctttttgaaa tgagggattg gctaagtgat gagagaattt gaaaaatcca
     1801 acaaattaga aggtgtcagt tacgatgttc gcggtcccgt tctagaagaa gcggagcgga
     1861 tgcaagaaga gggcattagt attttaaaat tgaacacggg aaatcccgca ccttttggat
     1921 ttgaagcacc aaacgaagtc attcgtgatt tgatcatgaa tgcccgtgac tcagaaggct
     1981 actcagattc caaggggatc ttttctgcta gaaaagcaat tgagcaatat tgccaactga
     2041 aacattttcc gaatgtgacg atcaatgata tctacaccgg caacggagtg agcgaattga
     2101 tcacgatgtg tatgcagggg ttgctggaca atggagatga agtactggtt ccaatgccgg
     2161 actatccgtt gtggacggct tctattgcat tagctggagg cacacctgtt cattatattt
     2221 gcgatgaaga ggcagaatgg tatcctgata ttgatgatat caaatcaaaa ataacgagtc
     2281 ggacaaaagc tattgttatc attaatccta ataatcctac tggggcactt tatccaaaag
     2341 aattattaga agaaatcgtt gaagtagctc gacaaaataa cctgattatt tattccgacg
     2401 aaatctatga tcgcttagtg atggatggtc tagaacatat tccgattgct acattagcgc
     2461 ctgatttgtt cgttgttacg ctgaacggtc tatccaaatc tcatcgtgta gcaggatttc
     2521 gagtaggctg gatggtccta agtggagata agtcacacgt caaaggctat atagaagggc
     2581 tgaatatgtt gtcctccatg cgtttgtgtt ccaatgtatt gtctcagcaa attatccaaa
     2641 ccgcgctagg cggttatcaa agtgtcgatg agctgctcct gccaggcgga aggatctatg
     2701 aacaaagaga atatatctat aatgcaatca atgatattcc tggtctttca gccgtaaaac
     2761 caaaagctgc tttttatata ttcccaaaaa ttgatacaaa gcgattcaat attttggatg
     2821 atgaaaaatt cgttttggac tttttacatg aacatcatat tctacttgta catggtggtg
     2881 gatttaattg gaaccagcca gatcattttc gaatcgttta tcttcctaaa atggatgatt
     2941 tgaaacaaac agctaagaaa atgagagaat tcctagcaac ctatcgccaa aaatgatttt
     3001 aaaaaccaaa tttttcagta ggagggccac agacaaacac actgaggctc tctttctagt
     3061 ggagttttct taaataacta aagtatatta tttagttgca agtcttttct tgaagtttgc
     3121 gacttcctaa agtaaaatac gaatagaatg cgaatacgca tattttgggg aggatactta
     3181 tggaaacgtt aatcgagtcc tttggaacga tcattaaaga gattcgaaaa gaacaaaaaa
     3241 tgacgcaaaa aatgctttcg catgatattt gttcacaaag tgtattaagt cggatcgaaa
     3301 ataatgagga actgccgaat gtattggtga tgatgcagat ttgtcaacgg ctaggggtaa
     3361 cgattgatca tgtgatgaat ctctctcgaa aaactactcg gacaaacgat aaattatttg
     3421 aactgttgga tagttgtttc caaaaacgtg attatcggaa gttagaacaa gtactaaaat
     3481 cttctgatat ttctgaaaat ctgtatcaag caactgactt tcaacgctat tattattatc
     3541 tcggtgtttg cgaattcacg ttgcgtcaaa atatctctca gtccctttat tatttgaaag
     3601 aagcattaag ctactctagc caaaaagaaa gaatccatgt ttctgacaca gaaatacaac
     3661 tgattagttg tatcggaaaa atatatggtg tggcaggaaa aacggctgaa gcacgctact
     3721 atttgagtcg aagcatccaa ctgctgcatc aatcagctga tgaacgatca aaaagtgaat
     3781 tttcgcaaat tttttataat tatggaaatt tcttattcca tcaaaatgaa atcgacgaag
     3841 cgttagaaca ggtgaatcaa ggaatctatt gggctcaaga gaagaatagc tactattacc
     3901 tcaatgattt atttgtgctt aaaagcttaa tatacaagcg taaagaagaa ccagaaagag
     3961 cagcattcta tgaaggctta gcacaagctg tgaaacaaat ttcaaaaaat ttgtaaatgg
     4021 tgtagaccat tcttgacttc ttctctaaat aagagtactt tagaggtaga aaaacaaagg
     4081 gagagaatag aatgagaact tttatctatg ctgacaaatt ctttttagcg tcaggtgtca
     4141 aacatgcagg ctatcttgaa attaccgatg gactttttgg tgaatacacc aaagaactac
     4201 ctgagggaga agtcaacatc attgaccaaa gcggcaaatg gattgctcct ggtttggtag
     4261 atacacatat tcacggctat atgaatcatg atgtaatgga taatgatgca gaaggcatca
     4321 aagtgatgtc tgaaggtctg ttatcttgtg gagtgacttc atttttacca acaacattga
     4381 cgtcaagcaa agaacgttta aaagatgtag ctgagacaat cggcaaaatg tatcaggaag
     4441 caccaggagc taaaatcaaa ggaatctatt ttgaaggtcc tttcttcaca gaagaacaca
     4501 aaggggcaca aaacccaagt tatttcgggg atcctgattt ggatactttc catgaatggc
     4561 aagaagcttc aggtggttta atcaaaaaaa ttgctttagc accggaacgt caaggtgtag
     4621 aagagtttgt caaacaagtg actgaagaag gagtagttgt ttctctagga cacagtaatg
     4681 ctacactaga agaagcgcaa aaagctgttg aagcaggcgc aagtgtattt gtccatgctt
     4741 tcaatggtat gcgtggattg aatcatcgcg aaccaggtat ggtgggtgcg ttattatctt
     4801 tagaacatgt cttttctgaa ttgatttgtg atggccatca tgtacatcca aatgctgcgg
     4861 gaatcctaat ggaaaaagca ggacatgatc atgtcgcatt aattacagac tgtatgatgg
     4921 ccggtgggat gcctgatgga aattacaatt taggcgaatt tccagtagta gtaaaagaag
     4981 gaacagcacg tctagaatct ggcaacttag ctggaagtat attgaaattg aaagaagcaa
     5041 ttaaaaatgt tgtagactgg ggattagcaa caccagaaca agcagtcatg atggctagtc
     5101 tgattccagc aatcagctgt aaaatcgatg atacatgtgg aaaaatcgct caaggacgcg
     5161 atgcagactt tatcgtattg aaccctgata tgacattgga agcaacttat ctagatggcg
     5221 tggaacgttt ccacgcataa tataatttaa gttaacctta aaactaaact tcttaagttt
     5281 ggttttaagg ttttttttgt gttctagtaa aaatcacttt acataagttt caaaagtttc
     5341 tttaatttcc tattgttcaa taagtaacaa tgtaaagata aaattaaaaa tgttaatacg
     5401 tattagcaaa ataaaagctt tttttattgt gaataaatga acataattag gaggagaaag
     5461 atgaacttat ttgacatttt tcgatcgact ttgacagata tgtcgattgt cagtgcaatc
     5521 acttcaacag tttttattat attattaggg tttgtttgta gaaaaaaggg gattttttct
     5581 gaatctgttg gaaaaattct atcgaaagtc gtcttaacag tggctttgcc agcactggca
     5641 tttcgagctt tcatgcaaga tatcaataca gaattactga tgcaaggaat caatgtcttg
     5701 atttggggat tagttattta tattattctt attctagttt caaaaccttt tttcttaagc
     5761 tataaagggg ataagcaaac aacgttgcgt gtcctgacga tctttggttc tacgaccttt
     5821 ttcggaacgc ctatcgtcag tgcgatttat ggtcctgtcg gcgtgatgta ttcctcaatt
     5881 ttcaatattg gctaccgaat ctttttgtat tcttatggat acataaaaat gagtggcttg
     5941 aagatggaag ctaaaaatat caaagcgatg ttcgtcaatc caatcattat cgctactttt
     6001 gccggccttt tcatttggct gttccaaggg tatctgccac aagtgtcagt tacaggtgca
     6061 gaaggagaga taagccaagt agcgtttttg cgaattgacc agactgcacc gtggctattt
     6121 cagccgatgg attatttagc tggtttaagt tcaccattgg cgtggctagc aatcggcgca
     6181 acattaggtg aagtaagctt caaaaaagct gcatctgaaa aaacttcatg gtattacagt
     6241 ctagtcaaag tggtatttgt acctgcattg aatatcgtga ttctagcagt tttgacggca
     6301 acgaatattc taccagtcaa ttttgaagca ctggcaacaa tcgttatcat gatggctaca
     6361 ccagctgcaa cagtggcagc agcctatgct atcagttttg atagggaggc acttttagcc
     6421 tccaatgcat ccttactgtc aactattttt gctgtggtac tgacacctgt atggatcgtt
     6481 gtattacaaa tgattcatgg cataggttta ttttcataag aaatggagga agaaagtatg
     6541 agaatcgcat gttacggtgt tcgtccgaac gagatagatt tttttgaaaa attgaatatt
     6601 taccattatg atctcagtct ttatgaagaa ctgttgacac atgacaatat cgtgtcagca
     6661 aaggaccatg atgctgtatt gttgagggga aattgtatag cagatgagac caatcttgca
     6721 aaaatgcagg aatatgggat tcgttatgtt tttacacgga ctgtgggagt caatcatatc
     6781 gatctacaag cggcagctga ttttggtatg acagtagccc gtgtaccatc gtattcgcca
     6841 aatgcgatag cagagttatc tttgactttt gccatgatgc ttttgagaaa tactgcgtat
     6901 acgacgatcc gaacatcttt caaagatttt cgagtggatg agcaaatgtt tagtcgtgaa
     6961 atcagaaatt gcacagtagg gatcatagga acaggcagga tagggttgac ggaagctgtt
     7021 ttgtttaagg gactaggagc caaagtgatc ggctacgata ttcatcagac agaagctgct
     7081 aaaaaagtat tgacgttcca ctcgcttgaa gagttattag ccaaaagcga tattgtcagt
     7141 attcatgtac ctcatatccc aggtgaaaac gatcaaatga tcaatgaagg atttttagct
     7201 caaatgaaaa aaggtagcat cttgattaat acagcccgtg gagagcttca agataatgaa
     7261 gctattttaa gagctttgaa aagcaatcat ttagctggtt ttgcaaccga tgtttttgca
     7321 aatgaaacag aggttttttt ccgatccttc aagccatggg agacgattcc agaccctgct
     7381 atccagcaat tagtagaaat gtaccctaga gttcttgtaa ccccgcatgt aggttcaaat
     7441 acagatgagg cattatcaaa tatgatttcg acaagtttcg agaactttcg tgaaataata
     7501 gaaactggaa aaacgaaaaa tgaggtatct cttcctaaag cccgtcaatt aagataagaa
     7561 aacatggata ttcgtcaata aaatgtttaa aaatagtcca agtaaacagt tgttacttct
     7621 gtatacttgg actattttgt atgggataat tcgatgactc aacagtaatc tgtgagcttt
     7681 ttccgcccat tctttgtcaa ttcataacag gttagcggcc ggccgatttc caaatatttg
     7741 attctttcgt tcaatatatc ttgttctact aaaaaattca aatatttctt gacggatata
     7801 cgtgacagtg agcttttttg agccagttct tttgttgaaa aaatagtatc ttcttttaga
     7861 ataaatgcac ttattttttt taaagtcagt tttgacagac ctttaggcaa atcgatgaat
     7921 gatggtattt cgtgaatggg agtggtgtgg ttgaatactt gatcgatcaa tttctgatcg
     7981 gctttttcag tcgtttggat tgtctgagag aaagcaagat acttttcgat cgccagctga
     8041 aaacgttgca aagtgaacgg tttgatcaaa taatctaagg caccgtagcg gatcacattc
     8101 tttatggttt cgatatcatc tgcagcagtg atcaaaatca ctgggatatc atttccttgc
     8161 tgtctaagcc aagataaaaa atggatacca ctttcgccag gcatgtatac atcaagcagc
     8221 agcagatctg cgtttttttg tctgaaatat ttttttcctt cttctacatt tctgaaactt
     8281 tcgattacgt tcatattagg gatgctttcc acaaaagtac gattcaattc tgcaaccatt
     8341 ggatcatctt cgattatcag gacatttgtc atcattttga tcttcctttt ttggtaattc
     8401 tagatagacg attgtaccgc catttgtttg tttggaaaat tctaaaaatc caccgtggcg
     8461 tttgacgatt gaatggatga gattcaatcc aaacccacga ttgattccct tcgtcgaaaa
     8521 acctagcgta aatatttttt ctgagatttc ttctgatatc ccgacaccgt catcgcagac
     8581 ggtcacgatg aatacttcag cttctgtgtc atagtttaaa tgaatccgga cctgtccgtt
     8641 tctttcatgt ttttgtagca cggcttcttt tgcattatca agtaagttcc ctaacacttg
     8701 caaaagtgaa tggatggagt catccatctc cattttaggg ataaaagaat cgctttctaa
     8761 cagcatttca acagattgtt ctttggcttc gtttattttg cctaataaaa aaccggcaat
     8821 tgcaggtact ttgatcagac ttgagacttg gccaatctct tttttataat tttgatttag
     8881 ctgctggata aaatgggtga cttcttcata cttcttcaaa tcaatcaaac cagaaatgac
     8941 atgaagttta ttcatgaatt catgggtttg agctctcatg gagtttatat attgtttcgt
     9001 ccccccaagc tcctccatta atttcattac ttctgatcga tttcgtaaag ttgcgactgc
     9061 tcctaaaaaa cggtcattgc taaaaagagg tgtaacgcta gaaatagttt ctatcccatt
     9121 taaatacatg gattgagtcc gaacggtcgt ttgatgctca atcgtctctt taaacaaaac
     9181 gtcatataga ttatcactga tttttttcct acttcgaaat ccaatagctg ctctgtttgg
     9241 tagaaaatgt tttttgcagg tgtattgatc aagaggatag ttttatcaga agagatggct
     9301 aagattcctt catctacttc attttcgata atcgtttttt cacttaactg ttctgctatt
     9361 tcttgtggtt caagtccaag cagtactttt ttcatttttt gggcaagaaa aacggcgcct
     9421 atgatgccta cgctaagtcc aataatcaat gaaaaaacaa tcattttttg tccatctttg
     9481 acttgattgt caatcgtgtt gtttgttaag ccaacacaaa ctgcaccaat aatctcttga
     9541 tcataataaa tagggacgaa atagcggaag ccgaacccta acattccttc tttttcagag
     9601 aaaaattctt gtcctccaat cacttttttc acatcttcat gacttgagaa aggaagaccg
     9661 atgtaacttg ggtctgcgtg agaatatcga atgccttcag ggtccatgac aacgataaaa
     9721 tctaaattcg atgcaatcat gatttcattt gttattcctt gaatcgcatg tgtcgggtca
     9781 ccagtctgca gctttttttg gatgagttta tcattggcaa cgattttagc aatgctagag
     9841 attttatctg acacactaga tcggttcatc gaaagaataa aattcctgat caatatggca
     9901 gaaacaatca aagaaacgaa tgtggagaaa caaacgacaa ggatgatcgt gttctggagc
     9961 tttaatggtt ttttcttaaa aaaaggaaac ataggctacc tcgaaagaat ttattgtgaa
    10021 aattttaaca tgaaaacaaa aatttaacaa attgtcaacg ataaacacaa ccttcctata
    10081 aaaaacacca ctgagtcggt aaaagaagct atacagaatt ttcaaacatt ggtatgatag
    10141 acgtagaaat ggaaggaggc gtgtatatga tagggggaat cgcacttgag acgatttatt
    10201 ggtatacatt gctgatttgt gcaggattgg cagtcctatt gattattttt ggagatgtat
    10261 tcgattttga tggcccgctt gatccgatgc ttattatccc ttggttaact ttcacaagct
    10321 tatttggttt tctaggtgag cgtttaacag atcaatcatc tttattttta tttattgcta
    10381 gtggaggcat atcgatagtg ttggtatttt tgcttaattt ctatatattg atgccgatga
    10441 aacatgccga atcaacgatg tcgtcttctg aaaaaactct ggaaggacaa gtagctgttg
    10501 tgatcacacc gatccctgta cgaggtatgg gagaaattca gttgaaaagt gttaccggtt
    10561 ccattagtcg tccagcttgt ttttacagcc cccaagaaca gacagctgag cggggaacga
    10621 aagtattgat cattgagatc aaggaaagaa tctgttatgt catgccttat gaaagcatga
    10681 taaaagctta aaggagcgtg tgttaaatgg aaataccagt tgtttttatc gcgatcgcaa
    10741 tcgcagcttt gattttactg atgttgctga tcgtctttgt agcgaagtac cagacagcaa
    10801 aaccggatga agcgttgatc atcagtggaa gttatttagg aagcaaaaat gtgcacattg
    10861 atgaaagcaa taacaaaatc aaaattgtgc gtggaggtgg cgcattcgtc ttgccagttt
    10921 ttcaacgttc gaatcggatc agtctattat cgagtaaatt ggacgtctcc acccctgaag
    10981 tgtatacgga acaaggcgta ccggtgatgt gtgatggtac ttcgatcatc aaaatcggtt
    11041 catctgtaga agagattgct acagcagcag aacagttttt aggcaagaca agagaagaac
    11101 tggaaaatga agcaagagaa gtattagaag gacacttgcg ctcgattctt ggttctatga
    11161 ctgtagaaga aatctatcaa aatcgcgata agttcagtca aagcgtacaa gaagtcgctt
    11221 ctgtagacct tgcaaaaatg gggttgatca tcgtttcttt cactatcaaa gaggtcagag
    11281 acaaaaacgg ttatcttgac tctttaggga aaccaagaat cgcccaagtc aaaagagatg
    11341 cagatatagc agaagcggaa gctctaaaag aaacgcgtat caaaaaagct caagcagaaa
    11401 aagaatcaca agcagctgaa ttacagcgac aaacagagat cgcagaatca ttaaaagaaa
    11461 aagaactgaa attagcaacc tacaaacaag aacaagatgt tgctaaagca aaagcagacc
    11521 aagcctacaa tttagaaagt gcccgagcac aacaacaagt aatcgaacag gaaatgcaga
    11581 ttaaaatcgt agaacgtcaa aaacaaatcg aactggaaga aaaagaaatc acacgtcgtg
    11641 aaaagcaata tgattcggaa gtgaagaaaa aagcagatgc cgatcggtac gctaaagaac
    11701 aagaagcaca agctcaaaaa gtcaaagaag tgactgaagc cgaagcagaa cgattccgtg
    11761 tggaagcact ggcagaagcg gaagccaata agacacgttt agctggacaa gcagaagccg
    11821 aagcagcact agcaaaagga aaagcagaag ccgaagcaaa acaaaagatc gccaatgcct
    11881 tcaaggaata tggcgaagca gctgtcttga gtatggttat cgatatgcta ccgcaattga
    11941 tgcgcgaagc agcacagccg ctaggaaata tcgaaaaaat ctctgttgtc gatacaggaa
    12001 gcagttcagg agaaaccagt ggagcgaacc gagtgacaaa ttatgccaca aatttgcttt
    12061 cttctactca agaaacacta aaagcgacaa caggacttga cttgaaggaa atcgtagaga
    12121 atttgtcgac acgtgggact actagccaag taaatatgta tgaagcgcca aaagaggcag
    12181 aacaaaactc gatgaaggaa gaataaagta gtacacttca ccgttcaatc aaaaatggag
    12241 gaagactttt taaagttctt ctctccattt ttttatttta ttgcaaaaga aaattagtcc
    12301 tcgctatttt tcttttgttt ttggatctta gcttctatct cttgtaaatt tgttcttagc
    12361 aatcgttctt tcttttggag ttcgaccaaa tcttctgata gttcttcctt cttttctgtt
    12421 tcaggaggac gaagaaagaa attgataccg attgcaatga atgtccctat aaaagtatct
    12481 agtacacgtt ggatagcata caaagcggat tcgccttgag ggatgctcaa cgcaatcagc
    12541 aacaacgtag ctattgcgga aatgataccg gaattattgt taataccatc tgacacgacg
    12601 atcacaataa taactagaat aggaagcaag atcaattcta ccaaaaaatc attgtgaaaa
    12661 tagcttttga caaaaaaata aatgatagct aatgtaccac ctaatgtatt gccgatgatc
    12721 ctagactttc caaaagaaac ggttgtagtc aagtcctgac gcaaagaaaa aacagcagat
    12781 aatgcagcaa tcatcgggat tcctcgttga gtcaaatgaa aaaacaagat acataaaaaa
    12841 acagctaagg cacttttgat cgtacgcata cctagtcgaa aacggccaaa ttgcatagag
    12901 attctccttt ttggtctttt tactatcata cctaaacttt tgtctgatag ctagtttttc
    12961 attattcaag tataattaaa ataaaaaagg gggaagtaaa tgcgtatagg aatgcgaaca
    13021 gtcaaaacag tgatcagtgt cttcttttcg atggtcacag cgggtagctt atcgctgttg
    13081 tattggccag ctgcagggat cattgcatta ttaagtgtag gaaataccaa gcgctctaca
    13141 ttgcgtacgg gcatgaatcg aatcgcagcc tttatattag ctacggcaac agcactgttc
    13201 agtttttttg ctgttgggta tactattttt ggcttcagtc tttttttatt cctgttcatc
    13261 ccgcttgcct ctcgcttcaa attaaccgaa gggatagtag taaattcggt tttggtcact
    13321 cattatttag tggaggaaaa catgtcttgg cagctgatcg gcaatgaagc gggattaatg
    13381 gcgattggat tagtatttgc tttgcttgca aatgtttaca tgccagatcg tacgaagcag
    13441 ctgaaggaaa accaaataca gatcgaaaaa gaatttcgaa atattttgag acaaatggca
    13501 gaatttcttt tatcagaaaa taaagaagat gtgcagatca aatgcgaaca tttactgaca
    13561 ttcattcgcg aaagccaaga agatgccaga gaacatcaag aaaactactg gctcagacag
    13621 ccgctatact acgaaactta cttctctatg agaagagcac aggccaatgt gattaaagac
    13681 atgctggaaa atctagagag aatccagcaa ccagcttatt atggaaaaca tatctatggt
    13741 ttattgattt atactgcaga aacattttca gagtcaaatg atggcagaca aattttaaca
    13801 cgtattgaag aagtttatgt attgtatcgg caaatgcctc tgccgactag tcgccctgaa
    13861 ttcgaggatc gagcagaatt gttccagttt ttgcagtctt ttaaaagttt tattgaaatc
    13921 aaggcagaat tctcccaaca aaaaatccaa aaatagaggt tgtgaattca gctaatattc
    13981 aggtcaaaaa gctgatttca caacctcttc tttaaacggt gttctcctgt caactcctcg
    14041 gtcacaagtc acaatattca acaaacatga gaagctgttt tttgaaattg ctccttgtga
    14101 ctcggagctg aacggtaggc tcacaacctc tttcttaaac ggtgttcaaa agctttcctc
    14161 tgcggtaata agtccagcca aacgaaaaat aggaggagct atttttgttt ggctgttctt
    14221 attacttgat gcagaacagc tttttcacaa ccttttaaaa ttacatattt ttccatagaa
    14281 cttgcatttg atccaagatt tcgatgacat cttttgtcaa gaagagagag cgattgggca
    14341 agtcaccttc aatcatgtgt accatattct ttatttcgta attcattgct tcagatgtat
    14401 tcccgctttc gatgaattcc tttgtaccat ctgtaaataa gatctccgca cgatcagcac
    14461 gcgggtaatc agcaatcgtc acataaccgt tctcaaaggc aacgataccg acttttggca
    14521 tttttgcctg aaaagtcaag ctgacagcag caagttcatt ttctttgtta cgcaagatag
    14581 tgacggattg ttcgtccacg cctgtttcaa aaggaaccat tgtagaggca actacttcag
    14641 gttgagagct caaaaagaaa cgagcgaaag atacagcata cgtaccgata tccaacagag
    14701 ctcctccagc taattctgga ttgaagaacc ggtttttagg gtctggttct ttgtaactgc
    14761 cgaaaggtgc ttggatcatt tttaaagccc ccagttttcc tgtatccatt attgagcgta
    14821 actgctgata aagtggcatg ttgaagattg tcatcgcttc tgctaagatc aaattctttt
    14881 cttctgctaa gcgcatagcg tcagccagtt cttttttatt tatcgtgatg gctttttcac
    14941 atagaacgtg tttgcctgct tccaatgctg ccaagatatg gtcgatatgc tgtctatttg
    15001 gtacagcaat gtacacgatg tcgatttcag catcgtctaa catttcttga tagcttccgt
    15061 aagcttttgg aatattgtaa cggtgagcga agttttccgc tttttctgaa gttctggaag
    15121 caactgctgt tagttcgctc gtctcttgat tgaagctttc ggcaaactca tgtgcgatgg
    15181 taccaagacc aacgattccc cattgatatt ttttcatctg aaaacgctcc ttcatagttg
    15241 gattgagttt cttgtctgtc tattattata acaaaaatca cgaagaataa agaggagagg
    15301 acttgaaaca ttaaaaaaaa tgaaagcagc gatttaagag gtgctttttg atcaaaactt
    15361 aagtagaata gttaaaagga ggggataaac gtgcatcaag tatatattga tcttattatg
    15421 agtgtattat tagaacagtt tgaaactgaa aaaaattttt tagatgaata cttgctgatc
    15481 agtccagaac aatggcaaaa atggaaagat ggcgagaaaa atctgccatc tgaagcgatg
    15541 cagaaagtaa aaaatctttt cactgattat gaatggatgc taacgcaaaa gattttgcgt
    15601 caaacgatta tttttcccga aaaacgaaac gttgccgttg cagagtacaa gcaaatcaaa
    15661 acacgcatcg cgcaaaaatg gcttagcagc aaagcagcaa aagtcgagct gatccctttg
    15721 aaaaataatc agcaggctgg tagatacctt gacttgaaag taagtattca atatgatgaa
    15781 tggggctatg atgatatttt gaattttcgt ctgccagcag atgttcaaaa acagatcgaa
    15841 ggagaaaaaa tcgaacttct cgattgggtg aatgaaaatc tggaagaaac ttacgttcat
    15901 gaggcgaatg gggaacgtga agaacaacga aaggattttt caagtgaata aatttttagg
    15961 atttggagca gttgtgatta tgatcgcagc aatgggctat gttattttta gcgatgatga
    16021 ttcgcatgtt caagccggca atcaagcagt cgaacgaaca agcaccaaaa caactgctag
    16081 taaagaaaag aacagtcaaa caaccagcag caaggtaaag gacaaagaaa caaaagatcg
    16141 tacgtccaaa caattgccag atgttaaaac agacgattgg aagctagttt tggttggtcc
    16201 agatcacaaa ttagaaaaag aaattgatga gtctactcaa ttggcatcat taagtaacgg
    16261 atacttgatc gacaaacgca ttgctccaga atatgaagca tttgccaagg ctgctgaagc
    16321 agctggattt ccattagtga tggtctcagc ttaccggtct gtatcatccc aacaacaagt
    16381 tttcgaacaa aatgtccaag atgtgatgag tcgtcaaggt gtatcagaag aggaggcgac
    16441 aaagattact aaagaaacga ttacggagcc aggatacagc gaacaccaca caggtctggc
    16501 agtcgatgtc gtcgatcaaa actggtacaa cagttatcct tctactgtat tggatgcaag
    16561 ttacggagat cagcctggag ctaaatggat cgcagataat gctgcgcagt atggatttat
    16621 cgttcgttat ccaaaaggac acgaagatat aactaagatc acatatgaac cttggcactt
    16681 acgttatgtc ggtaaagaaa acgctgagta tatcaccaaa caccaattga cgctagaaga
    16741 atatctgaat gaattaaatg aaaagtagga attgatcatg gcgaaaaaaa agtggaaaaa
    16801 gcaaaagcgc aagaatatcc gttggccagc agtggttgcc ggtgtagcag tgatactctt
    16861 agcctttgtt ttttccttga agaatctgtc ttctcctttt actgataatc agcaagaaaa
    16921 tgaagcgcaa tcccatcagc aatttattga acggcttgtt ccgcatgccc aagaactaca
    16981 agatggttat ggagtgcttc ctagtatcat tttaggacaa gctatattag aatcaaattg
    17041 gggaaaaagt accttggcta gcaaatacaa taatcttttc gggatcaagg cttatgggga
    17101 tcagaagaaa gtaagcctgg aaacaaagga atttgttaac gaagaatgga taactatcca
    17161 aggagacttc aaagtgtatg attcatggga acagtccatg gatgaccata cacaactgtt
    17221 cgtccaagga gtagattgga atcctgcgct gtatgaaaaa gtgattacgg ccaccaacta
    17281 tcaggaagcc gcacaagcat tgcaagatgc aggttatgcg acagaccccg gttatgcgca
    17341 aaaaatcatc caggtcatcg agacgtatca attgaatcag tatgaccgga gatagcaaag
    17401 gagaagtggc tgatggcaga acaatttacg ccagaaatca tgacggaatt gagaaaagat
    17461 atcgtaagag taccggaaat cattttagaa gcaagcggga tcaagatatt tggaaaattg
    17521 atccgttcga tcatctttac tacggatatt gcgatcatac gtaatacaaa tgcgaatgca
    17581 gtaattgctg tgtatccttt tacacctcat ccagcgatta ctaaaagcat tattgaggca
    17641 gctgacattc cagttttctc cggtgtaggt ggtggtttga cacaaggtgc tcgttcttcc
    17701 tacatgagca tgttcgcaga agcgcaaggt tcgttagggg tcgttttgaa cggtcctacg
    17761 cctttagaga cagtaaaaga agtttgtcga gtagttgata ttccagttat cagtacggta
    17821 acgtcgaaat atacagaaat agatgaaaag ttagcagctg gtatttcgat tatcaatatc
    17881 agtgcaggta aagaaactgc agaagcagta cgccattttc gtaaaaaata tcctgaactt
    17941 cctatcattg cgacaggtgg tccaacggaa gaaagtattg ctgagaccat tcaagcagga
    18001 gcaaatgcca tcacatatac gccaccaagt agcggagagc tttttagtcg taaaatggaa
    18061 aaatatcggg aaactgagaa aaagaatcat gaataacagg tgagaatcaa aagacgagga
    18121 agagcagata gtggctcttc ctcgtctttt gtactccagt actatttgtt cagaattcaa
    18181 aaaaaagaga aatttttttg tttttttacc tgtaatgtac ataagaagag ttaaaacctt
    18241 ttgttattat tagcattcta acaaaaaaat gtcttgattt attgaagcgc tttctataga
    18301 atgaaaaacg aataaaaact aaaaaaggca cccgacaatt tagtagcagc taaattgtcg
    18361 gggcttgaaa agtcagcggg aactgaccaa tcaagttgcc atagtcaatg cttgtgcatc
    18421 gacgtgtata ttgtacctaa tttcatacag aattactagt tatttttctg ttttttaggg
    18481 aagagcgcac acgaagaagc atgcttattt agctatgtca aggatattgg gcagttgtct
    18541 gatatccttt tttctttgcg taattatcct cccatcattg aagcaagaag tgtttttagc
    18601 gatgaaagaa gaatcagcac tatctaattt ttcttgaaag tattgagttg ttcatcctag
    18661 gcagaacgat aaggcaagtc ttggttttta ttccccttga aaaagatcgt ttaataaata
    18721 tgttctgtat aaaaatacag tatattgaaa aataacaatg gaagtagagg tgcagagaat
    18781 gaagaaaaga atgagaatca tcttagcttt aagtgttatg ttattcttct tgacggcttg
    18841 tgggcaagaa gatgacaaaa aaatcacgct gaacatggct tggtggggtt cgcaagtccg
    18901 acacgatgca acagtaaaag taatcgagct ttatgaagaa aaaaatcccc atgtgacgat
    18961 cgattatgaa ttttatgatt atgaaggata ttacacaaaa ttaggtacac tagcagcatc
    19021 agatgatatc tgggacattt tccaactgaa caatcaattt cctcaataca tcaatcagat
    19081 tgaaccatta gatgaatatg tggagcaagg gataattgat atttctaatg cagatgaatc
    19141 ctatttagca acgacgactt acgacgggca attagttgga ctgtctaacg gggtgaattc
    19201 gtttgcgatt gcttacaata aaaatatatt tgaacaatta aatatccctg aaccagcttc
    19261 aaattggaca tgggatgaat ttgaacaaat cagctatcaa atcactgaag aattaggaat
    19321 ctatgctatt tcaagattcg aagattttat agctggctgt attattcaaa taccacaagt
    19381 tgagaaagga ttgaattttt ataatcggga agatctatct aacagcttgg gatttgaaaa
    19441 tccagactat ctaacagatt ttttccagct gcgtaaaaat ctggtagaca aaggggccca
    19501 tccagaacca ggtggtggag ctgcaagtac gacggatctg tcttttcagg cggttaggga
    19561 tagagaagcg gcaatggtgt ttctatcaag taaccagttg acagaaatat tgtcaggggc
    19621 tcctgaagat atggagattc agttgattaa tccacctcgc agaaaagcag atggagaatc
    19681 tggtatccct ttacgttctt cgcaaatgct gagtatggca aaaagctcag cccataaaga
    19741 agaagctgct aagtttattg atttctttca aaacagtgaa gaagccaatg aaattttaaa
    19801 aggagaacgt ggtgtaccaa tcatgtcgaa tattcgagaa cagctcgctc gtgcagatga
    19861 tgcaactttg caagcgacat ttgattattt agaaatgatt tccgatatgg acaacggcga
    19921 agtgaatgtc tttgatagtg ctttgaatcc ggaaattcaa gaccaataca atcttttagt
    19981 tgaaaaagtc atttatgaag aagtaacagc agaagaagca gcagagagtc tttatgagtt
    20041 tgcgtcaaac attctaggat agcagcagga ggaaggcatg aaaaaagaaa aactaaaacg
    20101 gttcttggat caagacaatg tggtcggtta cgtatttgct tctccattca tcctaggatt
    20161 tctattgata acagtgatac cgatgatctt gtcactttat tattcgttca ccgattatcg
    20221 tttgggaaat ccagtctcat ggatcggctt ggataattat ataaagatgc tgagtgatgc
    20281 ccgttttttg aactccatcc gagtcacttt tctctatgta tttgcatctg tacctgtgaa
    20341 actgatcttt ggtctattga ttgcttatct tttaacgagg aatatcaaag gaacgacttt
    20401 ctttcgttct ttgtattatg tgcctagttt gatcggtggc agtatttcta tcgctctagt
    20461 ttggcgggag ttgttttcta aaaacgggtt agtgaatatt ttcctggaac gattaggcgc
    20521 acctgcgctt tcctggttta gcgatcaaaa actggtcatg atccctcttg ttttgatgtc
    20581 tgcttggcaa ttcggttcgg caatgatcat ctttgctgca ggtatcaaag agatcccagg
    20641 ctcgtattat gaagcggcag agatcgatgg agcgaacaaa tggcagacgt tttacaagat
    20701 cacgttacct cttctttcgc cgatcatttt gtataacttg gttatgcaga caatcgcggc
    20761 gtttatgact tttacgcagg catttatcat tacccaaggt ggtccgaatg atgccacgaa
    20821 cttttatgct ctttatgtgt ataaccaagc tttttctttt aattctatgg ggtatgctag
    20881 tgctatttcg tggatcatgc tgttgattat gggagctgtc acctttctga ttttcaaatc
    20941 atcaaaaaaa tgggtcgttg tgtgaatgag aggaggaaga aatgaataat acagtaacga
    21001 aatggtttca atacggtttt attttgctat taggtctagt catgatttat ccggtcttat
    21061 ggatgatcgc aggttctttt aaaacggatc aagagattat gagtggttcg ctgaatttga
    21121 ttccagagac ttttcaatgg gaaaattacg caaaaggatg ggcggggttt gctggaattt
    21181 cattttttac tttctttagg aattcgtttg tcatctctgc agtttcgacg atagggacag
    21241 ttctgagctc gacttgtatt gcttacgcat tatcgagaat cgatttcaaa ggaaaaagat
    21301 tctggttcgt cgtcatgtta gtaacgatga tgattcctgc acaagtgatt ttgattccgc
    21361 agtttattat ttacaatcgg ctgaatttgg ttgggacgta tgtgccgctg attttaccac
    21421 atttttttgg acaagcattt ttcatttacc agatcatgca attcatggtc agcatcccca
    21481 aagagttaga tgaatcagcg attattgacg gatgcagcaa gtatagtgtc tttaccaaaa
    21541 ttatttttcc tttgctgaaa ccttcgatca tcacgacgat catcatccag ttttattgga
    21601 aatgggacga cttcatggga ccattgattt atttaaacaa gccgagatct tacacggtat
    21661 cgattgccat caaattattt gcagacgctg gatctagtac gacttacgcg agtatgtttg
    21721 cgatgtctac gttgtcgctg ctaccggttt ttctgatttt cttattcttc aataaatatc
    21781 ttgtccaggg gatcagtaca agcggtctga agggctgaat atgaaaaagc caatagaaga
    21841 gatgtttctt tacaagctca actactatgt ctgtcggatt tttttaacca gtcttatcag
    21901 taatgctctt ttcgctttag ttctaggatg tttgttcact ttaggattag tgctgtctgc
    21961 tcgtgttgtc tatctgattt attttttgat gatgtatcct tcttattatc tatctgtcca
    22021 ttacttggca gaaaaaaagg tatgttggag gaaaggaaaa atcaaacgga tgtgtttcat
    22081 cattacgttg tttcagctgt ttgtcattat ttttgcagtt gattggtatt tattagtggg
    22141 aaagattgga gcttggtatc tgattccttt tctattgtgt ctgttgcttt ttgtatccca
    22201 tagttttttt agtacgctaa ttgatatctg caaagaagat aaagcagata gtcttgttta
    22261 tttgatcaaa aggaatatct ggctgttgtc aaaaaacgtc aaggggtttc tgtggtattt
    22321 atgccttttg tatggactgt tctggtgtat acagcatgat tttttactca ctgcattact
    22381 gtatccaggg ctgccatttg tcacagtatt ttgcttaaaa gaaaaggaga atgactttaa
    22441 atgaagaaaa aatatgtaca agtcggactt ggtgggagag cgcgtttttt ttatgaggca
    22501 attgcctcta cgtatcatca aacttgtgaa ctagtcggtt tttgtgatgt atctcaaaca
    22561 aggatggatt atgcaaatcg gatacttgtg aacaagtatg gacagaaaaa agtaaagaca
    22621 tgtatgccat cacaatttga gcaactactg gatgacgtac ggccggctga agtcattatt
    22681 acgtcagtag atcgaacgca tcatgattat atcattcgtg caatgaaaaa aggatatgat
    22741 gttatttgcg aaaaacctct gactatcgat gaggaaaaag ctcaagaaat aataacggtc
    22801 caaaaacaga cgggaagaag cctgcgagtc acttttaatt atcgttatgc accgtatcac
    22861 acgaagataa aggaactgat agaaagtgat gtgattggta atgtgttttc tatccacttc
    22921 gaatggctgt taaatacgca acacggggca gattatttca gaagatggca tcgaaataag
    22981 cacaatagcg gcgggcttct tgttcataaa tctacccatc attttgatct agtgaatttt
    23041 tggttgaaca gccgtcccca aaaggtattt gcattcggtg gattaaactt ttatgggatg
    23101 cataatgcgg agaaacgcgg agtagaaata ttttacagtc gatgctatgg aagcgaacta
    23161 gctaaagctg atccatttgc tatagacctg tcagccaatg aggaattgcg agaaatgtat
    23221 ttagaagcag aaaaagacag tggatatatt cgtgaccgca gtgtattttc cgatgatatc
    23281 tctattgaag atacactagg cgtaacggtc aaatatgaaa ctggtgcgat tttgacgtat
    23341 tcgctaaacg cgtatatgcc gtgggaagga ttcaatgttt ctttcaatgg cagcaaagga
    23401 cggatcgaaa tgaaagtgat cgaaaagtct tacatcaatg caggtggaga taaaaaggat
    23461 gaaggagcag ccgttcttca gtccatccat gtctatccga tgttcggtga gccatatgag
    23521 gtaatcgtcg aacaagaagc gggcggacat ggcggaggag atccgcgttt attagatgat
    23581 ctatttggtg aagaaaaaga agaagatccg tggaatcggg cagcaactca cgtagatggt
    23641 attttgtcga ttttgacagg aatcgcagca aatcattcta ttgcttcagg aaaagcagta
    23701 gtgattgacg agcttgtcag cttaaaagaa taagaataga tttacggaaa ttacttcccg
    23761 tagtttataa aatcttgcct tattgccgat aggctgtctt ttgaacacta tttattcgga
    23821 aaaaggggct atgacatgct ttttgtcatg ccttcttttt atgtgggctg cttttttaga
    23881 taggagaaaa taaaaataac tatttaaacc cgaacaaaaa ggaataatgc attaaaaatc
    23941 attagatttt acaaaaaaat aagtaaacca cgttgtcagt ttcagaaagt agtgttagac
    24001 tgttttcaat atttgaaaca acatttttta ttcaaatatg gcaaactgcc ttcacgtgca
    24061 aaacagttgc aagaaaatga atttacacta ttattagttt tacataccta cttatatatc
    24121 gtcataatat ggatgacagt ttctagccag taccgtaaat gctggactat aagtaaaaga
    24181 ttggctattt cacccttctt ttcttatgat aaagtggagg gtgtttttct ttaacagaaa
    24241 catagtaggt ttttgcacaa aagcggttat ttcggtatta ataaatgata aaggagcaaa
    24301 taaagtgaaa gaattagttg aacgtattca aaaagacgga cgtatattag gcgagggcgt
    24361 attaaaagtc gacagcttcg tcactcacca agtagaccct gtattgatgg aacaaatggg
    24421 aaaacggttt gcagaagtat ttaaagaaca aggaatcacg aaagttgtga ccattgaagc
    24481 ttctgggatc gcaccagctt tatttgctgc aagagaatta gatgttccaa tgatcttcgc
    24541 tagaaaagca aaaagtttga cgatggatga agaattattg acagcttctg tttattcttt
    24601 tacgaaacaa gtgacaagta cgatttctat ttctcgtaaa tttttatctt cagaagacaa
    24661 agtattgatt atcgacgatt tcttggcaaa cggacaagcg gcaaaaggat tgatcgaatt
    24721 atgccagcaa gctggagcgc aagtagaagg aatcgggatc gtcatcgaaa agtctttcca
    24781 agatggacgt cagttacttg aagaaatggg attgagagtc gtttctcttg cgcgtattgc
    24841 ttccttgacg aatggacaag ttgagtttct tgaggaggac gcataatcgt ggaaaaagaa
    24901 acacaaaatg gaaaagctgc ggttttaggg ctgcagcatc tgctagcgat gtatgcagga
    24961 gcagtagcgg tgcctctttt gatcggtaca ggactaggct ttaatcaaga acagatgact
    25021 tatttgattt caattgatat ctttatgtgt ggattagcga cattattgca attgacagtt
    25081 aaccgatttt tcggaattgg cttgcctgtc gttttaggat gtgcgatcca agcagtagct
    25141 ccactgatct tgatcggaac caatgaagga gtaggagcta tctacggatc tattatcgct
    25201 tctgggatct ttgttgtgtt agtttctggt gtcttttcta aaattaaaaa actattccct
    25261 cctatagtaa caggaacggt tatcaccgtt attggtttga ctttgattcc tgtagcaatc
    25321 gagaaaatgg gtggaggtaa tgcaacagca gctgattttg gtgacaaaac aaatctgcta
    25381 cttgcatttg tgacgattct cctaattgta ggcgtgcaaa tgctggcaaa agggttcatt
    25441 cgttcaatcg cggtattgat tggtttagtc ggaggaagca tcttagctgc tttcatggga
    25501 atgattgatc tgagcgcgat tggagatgcg ccgttgttcc atgttccaca acccttttat
    25561 tttggtaaac caactttcga cgtatggtcg attttactaa tgatcatcat ttccatggtc
    25621 agcatggtag aatcaacagg tgtatatttt gcacttggtg acattactgg gaaaaatgtt
    25681 ggagaagaag aattgaaaaa gggatatcgt gcagaaggac ttgccgttat cttaggcggt
    25741 attttcaata cattccctta tactggcttt tctcaaaatg tcggattggt tcaactttcg
    25801 ggaatcaaaa caagaaaacc catctatttc tctgcattct tcttgattgt tttaggatta
    25861 ttccctaaaa tcggtgcgtt agcacaaatc atccctgagc cggtacttgg tggaggaatg
    25921 ttagtcatgt tcgggatggt ggcagtccaa ggaatccgta tgctgttgga agttgatttc
    25981 agcaatgata aaaatctatt gattgttgct gtttctgttg gatttgggct gggtttcaat
    26041 gttacgccga cattattcag tcaaatgccg caaacattgc aaatgttcac tggaaatggc
    26101 atcgtaatga gtagcattac ggctatcata ttgaatttga tctttaatgg attgaaaaaa
    26161 gatgaagaaa tattggaaga agccttcaag aagtaataga gcaaaagaaa ggttgtgaaa
    26221 tcagcgtttt gacctgattg ttagagaaac aaacggaaaa atagttcctc gtattttgcc
    26281 gtttgtttga gctaataccg agggtcagct gattgaacac cgttgaagga agaggtcgtg
    26341 agcctgccgt tcatctccga gtcacaagga acaatttcaa aaaaaagctt ctcatgtttg
    26401 ttgaatattg ttccttgtga ccgaggagtt ggcaggagaa caccgtttat ccataaaaag
    26461 gaatgtgacc taacttttgt cacattcctt ttttttatct ttaataaaca cgaacaataa
    26521 aatgtttttc tttgttaaca ttcgaaattt ctttgacatc aaaaaaagtg attgttaaaa
    26581 tatgaatgta gaaaaactgg gaggaaaaac aatgacagca aaaatctctg tgattatggg
    26641 gagtacttca gattgggaaa caatgaaaga agcatgtcaa atattggatg aattcggtgt
    26701 gtcttatgaa aaaaaggtcg tttctgctca tcgaacccca gatttgatgt ttgaatatgc
    26761 acaaaacgct cgaaaaaaag gaatcaaaat cattattgca ggagcagggg gagccgcgca
    26821 tctgccgggt atggtcgcat caaaaacaac tttgccggtt atcggtgtac cggtccaatc
    26881 acgaacatta aatggtttgg attcgcttct ttcgattgtc caaatgcctg gaggagtacc
    26941 tgtagctact acagcaatcg gaaaagcggg agcaattaat gctggactac ttgcgataca
    27001 gatgctttcc atgtatgatt tagaattgga ggctaaattg gctgaaagac gttcaatgtt
    27061 ggctaaaact gttatagaaa gtagtgatca acttggttaa acctttgttg cctggttcaa
    27121 cgatcgggat cgtcggtggc ggtcaattag gtcgtatgat ggcgattagt gcaaaagaaa
    27181 tgggctttaa agtaggtgtg ctggatcctg tgagcgattg tccagccgca caagttgcag
    27241 attggcatat tgaaagtgtc tatgatgaca cctttgcgct gaaagagctt gccagaagaa
    27301 cagatgtcat tacctatgaa ttcgaaaacg tcagtgtaga ggcgttaaat gcgattttac
    27361 ccatgtcatt tattcctcaa gggacagact tgcttgcgat tacgcaagac cgcctgttag
    27421 aaaaatcttt tttggaaacg aataacatcg tgattgctcc ttatgcaacg atcgtcagtc
    27481 cgacggatat ccaagatgcg attgacggga tcggctatcc ttgtgttttg aaaaccactc
    27541 gaggcggcta tgatggcaag gggcagtatg ttttgaaaag tcgggcggat ctagctcctg
    27601 ccatggacct tttaagagaa ggaacctgtg ttttagaagc atggatcccg tttgaaaaag
    27661 agatttcgat catggtggca ggaaatggtc aaggagattt cacgactttt ccggtcgtgg
    27721 aaaacatcca ccacaacaat attcttcatg aaacgattgc tccagccgcg attgatcagg
    27781 atgtgatcga ggaggctgag cgtattgccc gtgtgattgc agaagcagtg agcctttcag
    27841 gtgttttagg ggtagaaatg tttttaacaa aaacaggcgg gctatatgtg aatgaattag
    27901 ctcctcgtcc tcacaattct ggacattatt ctattgaagc ttgttctatg agtcagttcg
    27961 atgcccatat tcgaggtatt tgtggttggc cattaggaga aaaagtacgt ttgataagca
    28021 atgcagtaat ggtcaatgtt ttgggagaac aactgctgga aagctatcgc ttgattgaga
    28081 ataagccaga ctggcaattc catttctatg gaaaaaaaca agcaaaaaaa ggtcgcaaga
    28141 tgggacatat cactatcttg acagaagaca tccagcaaac gctggaagaa atcaaacaaa
    28201 cgaatatttg ggattagagg agaaaaaaca tgttagaacg ttatacacgc cctgaaatgg
    28261 ggaatatctg gacggaagag aacaaatacc gtgcgtggct cgaagtcgag attttagcag
    28321 atgaagcttg ggcagaactt ggtgaaatcc cgcaagaaga tgtgaaaaaa attcgtgagc
    28381 atgcatcatt tgatatcgat cggatcttgg aaatcgaaaa attaacacgc catgatgtcg
    28441 ttgcgtttac acgagcggtt tctgaaacat tgggagaaga aagaaaatgg gtccattatg
    28501 gtctaacaag tacggatgtc gtagatactg cttatggcta tctcatcaag caagcaaatg
    28561 atattttacg ggaagacttg aaacgtttta cggaaatcat tggcgaaaaa gcaaaagaac
    28621 acaaatatac agtgatgatg ggtcggacac acggtgtcca tgctgaacca actacttttg
    28681 gattgaaact tgccacatgg tattcagaaa tgaaacggaa catcgaacga tttgaacatg
    28741 cggcaaaagg agtagaagca ggaaaaatct caggagcagt gggaacgttc gcaaatatcc
    28801 cgccatttat tgaagagtat gtatgtaaac aattggggat ccgtccacaa gaaatttcta
    28861 ctcaagttct ccctcgggat ctacatgctg aatatttctc agcgatggcg cttattgcta
    28921 caagtattga acgttttgca acagagatac gcggattgca aaaatccgaa acacgtgaag
    28981 tagaagaatt ttttgcgaaa ggtcaaaaag gttcttctgc tatgccgcac aaaaggaatc
    29041 cgatcggttc agaaaatatg gctggtctag ccagagtggt gcgcggacac atggtcactg
    29101 cctatgaaaa tgtcacatta tggcatgaaa gagatatttc tcattcttca gcagaacgaa
    29161 tcatcttgcc tgataccacg attttattga attacatgtt aaatcgtttt ggcaatatcg
    29221 ttaaaaatct aacggtcttt cctgaaaaca tgaagcggaa tatgtctgca acatttggtt
    29281 tgatttatag ccagcgcgtt atgctgaaat tgatcgataa gggaatgaca agagaagaag
    29341 cttatgatct tgttcagcca aaaactgcgt acgcttggga caaccaagtg cagttccgcc
    29401 cgctgttaga agaagatcca accatcacat cggtattatc taaagaagaa atagacgatg
    29461 cctttgatta tcatcatcat ttgaaaaacg ttgacgtgat attcaaacga gtaggtttgg
    29521 aataaagaag agtgagttgc aaaattcaat taaaatagaa tagcaaaaat aaccaaaaaa
    29581 gaagcagatc cgttagcggt tctgcttctt ttagtttatt atattttctt atcaataata
    29641 ggaacctgat tttaaaagcg gctacctctt taccgtgcct ctttacatac aaaaaataga
    29701 ggaattaagc gtaaatggct tggctattat aactaaaatg ctggttatgg agatgttgca
    29761 gcaagttttc gagaaaagcg tattccatct cttgtccatt gaataagatc tggatacgat
    29821 aatgattttt gaaacgcttc tgttcatgaa tctgactgat tgaaagttcg cctttgtgtt
    29881 ctgtctgata aagaaaagtc cttttacggc attcagcaca gcgtttggtt gctcggcgga
    29941 tttttcggaa tgtataaaaa ctagtatctt tattgcataa ataaacgtct ttgatcgaca
    30001 gcaaatcatt atatagacag gaacgttctt cagctgttaa ttctgataaa aaaagctgac
    30061 cttgttttat tgcatcttcc atcggcaagt gcctcctcga acccattatc caaattttta
    30121 gttaattcta atataccatc attaagtata aatgtaaacg cttgttgatg gtataagatt
    30181 ttcgtttctg ataaaacacg aacattaaaa gaatctaatg ccttaaatgt acatattttt
    30241 gttgatttat aaaaagatga ttgctaaaat ttaaagtgaa aaaacgaaca aaaaacgatg
    30301 tatttgcttt taatgtaaat aaaaaggaga gacgtacatg gagaagaaag aacttttgta
    30361 tgaaggaaaa gccaaaaaaa tatatcttac ttctgatgag aacttgattt ggatagaata
    30421 tttagatcaa gcaactgcgt tgaatggcgc gaggaaagac cagataagtg gaaaaggaga
    30481 attgaataat caaatcacaa gtgcaatttt ccgttatctg actcaaagag gaataaaaaa
    30541 tcattttatt gaacaattgt ctaaaaccga acaattagca aaaaaagtac aaattatccc
    30601 tctggaagtg gttatccgaa atattgcagc aggaagtttc tcaaaacgtc taggtgttcc
    30661 cgaaggtaaa gaattcatca aaccaatcat tgaattctac tataaggatg accagttgga
    30721 tgatccattt atcaatgaag agcatatcta tttcttacaa cttgcaaagc cggaagaaat
    30781 cagtgagctg aaagcccaag cgttggctat taatgaaatt ttgaccgaat tatttgctaa
    30841 ggtcggtttg gttttagtag atttcaagct agaatttggc cggtcgaatg gacaaatttt
    30901 gcttgcggat gaagtaacac cggatacttg ccgattatgg gatgaacgta cgaatgaaca
    30961 tatggacaaa gacgtttacc gcagagatct aggtgatttg atcccagtct atcaagaagt
    31021 atataaccgt ctatcggaac taactgaaga aaaggagcga gtatgatgta tttcgtaaaa
    31081 gtatatgtaa cctataaaga ttcagtgtta gatcctcaag gggaggcagt aaaaaaagca
    31141 gtccatcgta tgggatatga aacaatcgaa gatatccgaa taggaaaata ctttgagata
    31201 caacttgctg atgcagaaga accaatcgat acagtgattg aaacgatttg tgacaagctg
    31261 cttgcaaatg taaatatgga aacataccga tatgaaatca aaaaaatgga ggaagtataa
    31321 catgaaattt gcggtcatcg tttttccagg ttcaaattgt gacgcagata tgttatgggc
    31381 agttcgcgag atcatgggcg ctgatgccga atttgtacgg catgatgagt cctctttaga
    31441 aggatttgat ggggttttac tgccgggagg attctcctat ggtgactatt tgagatgcgg
    31501 tgcgattgct cggttttcta caatcatgga agaagtgatt cgttttgctg aagaagggaa
    31561 accagtattc ggtacatgca atggattcca gatattgaca gaagcaggac ttttgccagg
    31621 tgtactgaga cgaaatgagt ctttgcattt tatttgcaaa actgtaccat tgaaagtcaa
    31681 ccccaagacg gcctttactt cagagtatga agccgacgaa ataatctatc ttccagttgc
    31741 tcatggggaa ggaaattatt tctgtgacga agaaacactt caagaactaa aaaaaaataa
    31801 tcagattgcc tttacttata atgacaacat caacggcagc gtggaaaaca ttgcagggat
    31861 tacgaacaaa gcagggaatg tgttaggaat gatgcctcat ccagaacgtg cagtagaaga
    31921 cttgctagga tcagaagatg ggaaacggtt ctttgcttcc attttaaaaa acttcggaaa
    31981 ggtgaccgta tagatgaaaa cattgaaaga accgacagct gaagagatca agaaaaaaag
    32041 aatctatgcc gaatggggat tgactgatga agaatatcga atgatcgaag aagatatctt
    32101 aggaagaatg cctaattata cggaaactgg actgttttct gttatgtgga gcgaacattg
    32161 ttcctataaa aattctaaac cggttctacg caaatttcct actagtggac ctcatgtgtt
    32221 gcaaggccct ggagaaggcg caggcatcgt cgacatcggt gatggactag cagttgtctt
    32281 caaagcagaa agtcacaatc atccttcagc cgtggagcct tatgaaggag ctgcgacagg
    32341 agttggcgga atcatcagag atattttcag catgggggct cgtccaattg cgttgctaga
    32401 ttcattgagg ttcggcgaat tagataatcc aagaacgaaa tatttactag aagaagtagt
    32461 tgcaggtatc ggcggatacg gcaattgtat cggcataccg actgtaggcg gcgaaattgc
    32521 atttgatcct tgttatgaag gaaacccatt agtcaatgca atgtgcgtag gtttgattga
    32581 acacaaacat atccagaaag ggcaagccgc tggcgtcggt aattcgatca tgtatgtagg
    32641 tgcaaaaaca ggtcgcgacg gtatccacgg agcaactttt gcctcagaag aatttaatca
    32701 agaagaagaa cagcaacgtt ctgctgtaca agtaggcgat ccttttatgg aaaagctgct
    32761 gcttgaagcg tgtttggaat taatcttgca tcattcggat tctctaatag gtatacagga
    32821 tatgggagca gcaggacttg tttcatctag tgcggaaatg gcttcaaaag ctggctcagg
    32881 acttatattg acattagatg aagtcccaca aagagaaact gggatgacac cttatgaaat
    32941 gatgttatcg gaatcacaag aacggatgtt gatttgtgtt aaatcaggag aggaagaaaa
    33001 aatccaagaa ctatttcaga agtatgatct agatgcagtc actatcggta aagtaacaga
    33061 cgacgggcaa tatcggctat atcatcaagg agaagaagta gcaaatctgc cagtcgatgc
    33121 attagctgaa gatgcaccag tttatcataa agaaatgaaa gaaccagctc gaatcgtaga
    33181 atttcagcag ttagctcctt atcagccagt tatcgaagaa cctggacaag tattgcttga
    33241 tctgctgcag caaccgacga ttgcttcaaa acgttcaatc tacgaaactt atgattcaca
    33301 agtacaaacc aatacagttg tccgtccagg aagcgatgct gctgtgatga gggttagagg
    33361 gacgaataaa gcgttagcta tgaccacaga ctgcaacgcg cgctatctgt atttggatcc
    33421 aaaaatcgga ggacaaatag cagtggcaga agctgctaga aatattattg ctagcggtgg
    33481 taagcccttg gcgatcaccg actgcctgaa ctatggttct cctgataaac cagaagtttt
    33541 ttgggaatta tcgacttcag ctgacggaat tgctgctgcg tgtgaaacgt taggaactcc
    33601 tgttatttca ggaaatgtct ctttatataa tgaaacggat ggtcaagcaa tctatccaac
    33661 accaatgatt ggtatggtcg gattgattga ggatcataaa catatcacta ctcaggaatt
    33721 caaaaaatca ggggatctaa tctatatatt aggtaagacg tttgcagatt ttgatggcag
    33781 tgaattacaa aagatgcagc ttggaagaat cgaaggtgtg atccgaaact ttgatctatc
    33841 cattgaaaag agaaaccaag agttagtatt gacagccatc caaaacggat tgattgaaag
    33901 tgctcatgac tgttcagaag gtggcttggc aattgcactg gcagaatcag ctttcaaaca
    33961 tcagctaggg atatctgtac agtttgaatt gtcctctgct caattatttg cagaaactca
    34021 atcaagattt gtgttgacag tcgcaccgga aaataagaca cgattcgaag aaatgatggg
    34081 agatgctgct gttttagcag gtaaggtgac ggatgaagcg ataatcgaaa tttcagcaac
    34141 tgacggtcag atcaaaatag aaactgcagt agcaagaaag tgctgggagg atgcaatcgt
    34201 atgtcttatg aagtgaagag tttaaatgaa gaatgcggga tcttcggtgt ttggggtcat
    34261 ccagacgccg ctagtgtggc atacttcggg ctccatagtc ttcagcatcg aggacaagaa
    34321 ggtgcaggta tcgtgtccaa tgatcgagga aagcttaagg ggcatcgaga tttggggctg
    34381 ctttctgagg tattcaaaga tcaaagaaaa ttgcagcagt taacaggaga agctgcaatc
    34441 ggacatgtac gttatgcaac agcaggcaat ggaagtgtgg acaatattca gccttttcta
    34501 ttcaaatttc atgatcagtc gatcggctta gcgcataatg gtaacttgat caatgctcgt
    34561 tcccttagaa aagagttaga ggaaaatggg gcgatcttcc attctaactc cgatacggag
    34621 atattgatgc atttgatccg acgaagtgaa gaaacaaatt ttttaaataa attaaaaagt
    34681 gctttgaatg aagtcaaagg tggctttgcc tatttattaa tgacagaaac ggcaatgatt
    34741 gccgctttgg acccaaatgg ttttcgtcca ttagcaatcg gacaaatgaa aaacggagca
    34801 tacgtgattg cctcggaaac ttgtgcatta gaagttattg gggcacgttt tataagagat
    34861 gtccagcctg gtgagatagt gatcatcaat gacgaaggaa tccagattga ttgctttacg
    34921 aaggacacgc agctttctat ttgttcgatg gaatatatct attttgccag accagattca
    34981 aacatcgcag ggatcaatgt gcatactgca cggaaaaata tgggacggaa tttagcgaaa
    35041 gaatcgccag taaaagcaga tatggtcgtt ggcgtaccta attcttcttt gtcagccgca
    35101 agcggttatg cggaagctag tggaatccct tatgaaatcg gattagtaaa aaatcaatac
    35161 attgcccgaa catttatcca gccaacgcct gagctaagag agcaaggtgt tcgaatgaaa
    35221 ttatctgctg tacgaggagt agtggaaggt aaaaaggtga ttatggtcga tgattcaatt
    35281 gttcggggta cgacaagcag acggatcgtc catcttttga aagaagcagg ggcaaaagaa
    35341 gtccatgtga ggattgcttc tcctcctttg aaatatccat gtttttacgg gattgatatt
    35401 caaacgcgta aagaactcat tgcggcaaat cacacgattg atgaaatcaa agaatgtatc
    35461 ggtgcagatt ctttaggttt tttaagtgaa gagggtctga tcgaatcgat cggtctggaa
    35521 aaagatgctc cgtattcagg attgtgtatg gcttatttca acggagatta tccgacgccg
    35581 ttatatgact atgaagaaaa atatcaggaa tcactaaaag aaaaagtatc gttcttttaa
    35641 aagcagacca agaagggagt atatgaattc aatggcaaat gcatacgcaa aagctggcgt
    35701 agatgtcgaa gctggatatg aagtagtaga acggatcaag aagcatgtca aaaaaacgga
    35761 acgtttaggt atgatgggcg ctataggagg attcggcggt tgttttgatt tatcggtctt
    35821 tcaattaaaa gagccagtcc ttgtctcggg gaccgatggc gtggggacga aattagcagt
    35881 ggcaatcgaa gcagacaaac acgatacaat cgggatcgac tgcgtagcga tgtgtgtcaa
    35941 tgatatctta gcacaaggcg cagagccgtt atatttctta gactacttag caacggggaa
    36001 aaatgatccg ttacgtttgg aaaatgtagt aaaaggtgta gcagatggat gtgttcaagg
    36061 aaatatggcg ctgattggcg gagaaacagc tgaaatgcct ggtatgtact caggtaatga
    36121 ttatgatcta gccggatttg ctgtagggat agctgaaaaa tctcaattat tgacaggaga
    36181 aacgatcaac ccaggagatg tgttgcttgg aatagcatct agcgggattc attcaaatgg
    36241 gtactctctt gttcgcaaaa ttttctttga gcagcagcag ttttctttat catcaaaact
    36301 gccagaattg aaaaaaacac ttggcgaaga attgcttgag ccaacgaaaa tctatgtttc
    36361 ttccttgctt ccgctgatca aagaaaagaa aataaaagga gctgcacata tcactggtgg
    36421 agggtttgta gaaaatatcc cgcgaatgtt accagaatct atggctgcac aaatcaaact
    36481 tggctcatgg ccgattcttc caatattcgg ctgtttacaa aaatatggtg aaattcctga
    36541 gatggagatg tatgaaatct tcaatatggg catcggtatg gtcctggcag tcgaagaatc
    36601 gaaagtaaaa gaaatagtac acgaaattga gcaagctggc gaaaaagttt atgaaatcgg
    36661 gaaagtgatc gccaaagaaa aacatcgtgt ggtgtttata ggagaagaac gatgagaatc
    36721 gctgtttttg cttctggaaa cggaagcaac tttcaagcgc tagccgatta tctatcgaaa
    36781 aaaggattgg aatcttcgat tgactggttg ttttgtgatc agcctgaagc atatgttttg
    36841 aaacgtgcaa ctgcgttgag tgtaccggca gattgttttt cacctaaaga atttgattca
    36901 aaaaaagagt atgaagaagc aattttgcat aaattgaaag aaaaaaagat cgatttgatc
    36961 gtattagctg gatatatgcg aatcattgga ccggtattgc tgaaaaatta tgataaaaga
    37021 atcatcaata tccatccgtc tcttttacct gccttccctg gtttgcatgg catacgtgat
    37081 gcctttgaag ctggagtaaa agaaacgggt gtcacaattc attatatcga ccaaggtgta
    37141 gatactggac caatcatccg gcaggaaaaa gtgagaattg aacaggagga cacgttcgat
    37201 tctttagaag aaaaaatcca tagagtagag catcgaatct atccagaagt gattagtgaa
    37261 attattgaaa atggaggcta tctgaaatga caagagcatt gatcagtgta tcagataaaa
    37321 ctgggattgt agcattcgcc caaggtttga ttgaacaagg agtagaaatc atttcaacag
    37381 gaggaacaaa gcatgcgttg gataaagctg ggatcaaaac gctttcgatc gaagaagtga
    37441 cagggtttcc tgaaatgatg gatggccgtg tcaaaacact tcatcctaaa atccatggtg
    37501 gtcttttagg aagacgcgat ctccctagcc atatggaggc aatggaaacg gaaaatatcc
    37561 aaccaatcga ctttgtttgt gtcaatttat atcctttcaa agaaacgatt atgaaaccag
    37621 atgtcgaaat agcagaagct attgaaaaca ttgatatcgg tggtcctagt atgctccgta
    37681 gtgcagcaaa aaaccatgaa tttgtcacct ctgttgttga tccatctgac tatgaagaag
    37741 tactttcaga attacgtcag tatgggcata cttcactttc tttcagacaa aaactagcgg
    37801 caaaagtctt tcgtcatact gcggcatatg atgcactgat cgctcaatac ttaacggatt
    37861 gggtggaaga aaaagaaccg gaaaaattga cacttacgta tgaacgaaaa caaacgcttc
    37921 gttacggtga aaatagccat caagccgctg ccttttatca gtccgctctt ctggaaaaat
    37981 attcgatcgc agcagcaaaa caactccatg ggaaagaact ttcttataat aatatccgag
    38041 atgcagatgc tgcgctacgg atcatgaagg aatatgacga gccaacggta gtcgccttga
    38101 aacacatgaa tccttgtggt attgggacag catctacgat tttagaagcg tgggaagcag
    38161 cgtatgaagc agatcctgtt tcaatctttg gtgggatcat cgttttgaat cgagaagtag
    38221 atctgccaac agcagaacag atgcataagc tgtttctaga aatcatcatt gccccttctt
    38281 atacacaaga agctttggaa ttactgcaaa aaaagaaaaa catccgatta ctgacagtag
    38341 actttgcgca ggaagaaaat caaaatcgag aagaaacggt ctcagtctta ggtggacttc
    38401 ttgtacaaga tcaagatctg gcaatagaaa atgaagaaga gtggaaagtc gtgacaaaac
    38461 gtaagccgac tccagcagaa gcaaaagcat tagtgtttgc ttggagagct gtcaaacatg
    38521 tgaaatctaa tgcgatcgta ctggcaaacg aacgtcagac agtaggaatc ggagccgggc
    38581 agatgaatcg agtcggttca gtaaaaattg cgattgaaca agcgcaagag aaaatggaag
    38641 gtgcagtttt agctagcgat gcttattttc caatggatga ttcggttgaa tatgcagcca
    38701 aacatggtat aaaagcaatc attcagccag gaggaagcat caaagaccaa gattctattg
    38761 atatggcgaa taaatacgat ctagcaatgg tctttactga tgttcggcat tttagacatt
    38821 agagaggagt cggataaatg aacattttgg tgatcggtgc aggtggtcgt gaacatgcaa
    38881 taagtaaaaa acttttagcc agtccgaagg tggatacggt gtattgtgcg ccaggaaatc
    38941 cggggatgac aaaagatggt atcaattgtg tcgctatcag tgagcgagat cattcagcgt
    39001 taatccattt tgttaagaaa gaggctattg attggagtat cgttggtcct gaagttcctt
    39061 tgttaaatgg gatcgtcgat gattttatgg cggaaggatt gaaaatcttc ggtccgacaa
    39121 aagcagcagc tctgatcgaa ggttcgaaaa gttttgctaa acaattaatg gatacttatc
    39181 aaatcccgac agctaaatcc agaagttttg aatgttacga aaaagcagca gcgtatatca
    39241 aagaaaatgg tgcgccaatc gtagtgaaag cggacggctt agcagctggg aaaggtgtag
    39301 tcgtggctac cacagtgaag gaagcgctgg atgcggcaga acaaatgttg aaccagcatc
    39361 gatttgggga tagtagcaaa aaaatcgtcg tagaagagtt tttggcagga gaagaattct
    39421 cccttttggc gtttgtccgt aataccaagg tgtatccgat ggtcatttcg caagatcata
    39481 agcgggcatt tgataacgat aaagggccaa atacaggcgg aatgggtgct tattcaccag
    39541 taccgcaaat ttcaaaaaag atgattgaaa aagctgtgga agaagtttta aaaccagcgg
    39601 ctttgggaat gaaagaacta ggacgctctt tcacgggtgt tttatatgcg ggtttgattg
    39661 ctacgaagga aggaccaaaa gtgatcgaat tcaatgcgcg tttcggtgat cctgaaacgc
    39721 aagtcgttct ttctcggttg aagagtgact ttgcgcaagt aatcgatgat ttattagaga
    39781 atcgtacagt agagttaaag tggcagcaag aaggatacaa tgtaggcgtt gtggttgcag
    39841 ctgccggtta ccccgaagaa tatgagacag gaatggttct accagatttt ctggaagaag
    39901 agctttctgt ttactatgct ggagtttcct caaataacgg caaactagtt ggagcaggag
    39961 gacgtcttta tttagtagaa gcatacggtg agacgatcaa agaagcacag aaaaaaattt
    40021 acaccgcgtt aatggataaa acgacagatg gaacatttta tcgtacagat attggagaaa
    40081 aagctgccaa tagcgaactg atcgtgaagt aaatcagctg cttccattta taaaaaatac
    40141 aacaaacata atcggaagcg ccgattttag tgaagccttt tcataaagag tgtggtacac
    40201 ttttgttgtg tatataaata aggaggagtt cagatgaaaa aaattcaatt aggtacttct
    40261 gatcagaaag cagctgcagt gatcttaggc tgtatgcgta tcaacaatgc ggaagatcca
    40321 gtaaaagtga ttgagacagc ttatgaaaac ggcattgatt tttttgacca tgcagatatt
    40381 tatggaaacg gtgaatgtga agaaatcttt gcagatgctc tagcaaaaac atcaatcaaa
    40441 cgagaagatc tttttattca aacaaaatgt ggaatcgttc caggtgtgat gtttgatttt
    40501 tctaaaaaac atatcattga atctgtagaa aaaagtttga cccgtctgaa aatggattat
    40561 gtggatgctt tacttcttca tcgtccagat acattggtag aaccagagga agtagctgaa
    40621 gcgtttgatg aattggaacg gtcaggaaaa gttcgttatt ttggcgtcag caatcaaaaa
    40681 ccaatgcaaa tcgaattgct gaaaaaatat gttcgtcaac cattagtagc taatcagctg
    40741 caatttggct tgaaacatac tggaatgatc gatcaaggga ttcatgtcaa tatgacagat
    40801 gaagcaagta tcgatcatga cggtagtgta cttgattatt cccgattgca tgatatgacg
    40861 atccaagcat ggtcaccata ccagtatgga ttttttgaag gtgtatttat cgggaacgaa
    40921 aaattccctg aattaaacca aacattagaa gaactagcag ctaaatatca aacgacacca
    40981 actggcttgg cttctgcttg gattttacgc catccagcca atatgcaagt gatcgccggt
    41041 acgatgaacg tagggcgaat caaggaaatc gctcaagctt cagaaattaa tatgtctcgg
    41101 gaagattggt acgaattgta ccgtgctgct ggaaacattt taccttaaag attgtcataa
    41161 gcaggtcaaa agggctataa attaaaaaga cagaataact tgaaagctgt tttcagcttc
    41221 gagatattct gtcttttttt attgcaaatg gaaagagtat cattgtacgg atttcgttta
    41281 ttagttattt ttgtttttaa ggaaaagctg tgtccgatat tcttttggag aaatcccttg
    41341 ttttttctta aataaataac tgaaatagtt agggtcatta taaccaattt caaaagcaat
    41401 atctgaaata cgatagtctg attgctgcaa taattttttt gctaattcga ttctttgttc
    41461 tgtcagataa tcgatgaatg tttggttaaa cgattgagaa aaaatcgtac tgaaatgaga
    41521 gggacttaat gcaacttgtt gagcgaccca agttaaggac atatctggat cggtaaaatt
    41581 ttctttgata aaatccaatg catggttcaa aattggctga tatttgttcc ttgaaggctg
    41641 tgagggcaga gcagttaaga aagaaatgaa catataaact gtcgaacggt aaagcgagtc
    41701 gtcggcgctg attgctaagc gttgactggt ggatgtgcaa tgaaccattt cttgcgggat
    41761 tttcttttct ttcaggcaga catgctggag tagcttagtc aagacaaata aacgatataa
    41821 tcgtgttcga gttggtgtgc cttgtggttt cgtcaagtgt tcgatgtact tagatacttc
    41881 gtttttcgat aatgaagaca aatcaagtga gaggtcaaag taaaagacag aatcaactgg
    41941 aagtttcgct tcttgaatca aatcctcata gctgataatt tgttctttaa gggaactggc
    42001 ggtttcaagt atcatctgcg tgatctcaaa agatgcaggt aattcgctga ttctttctgc
    42061 gacaggacca atggcgacag aaaaattatt tttttgtccc ttttctaatt catggaccaa
    42121 cgtttgggct acctgataac tggtctcgat cacattttct tcaagagaat caactattaa
    42181 aaatttgatg aatcgagagg aaacagcaga gaagatcact tgttgattct ccctaaataa
    42241 aaacttcaaa taatcactga gatgagcgta atcttcaaag tctgtactga cttggtttgc
    42301 tgctaataat acggtcattt ttttccctgc taaagagcga ttgaaagatt cagcaagttt
    42361 caatgtttca ctgatcgtaa gtgagccttt gaacaaaccg ttcaagaaat gatttttttt
    42421 caattcgaaa acaagatcag aagaagtgtg cgtttctttt tgctgcaaat ctaaagcagt
    42481 tactgctttt tctattgctt gtttcaattc gctactttta atcggtttaa gcagataatc
    42541 atctgcctgt acctggattg ctcctttcat ataatcgaaa tcgtcgaatc cactaataaa
    42601 tatgagacga gtccaaggaa gtagtttcct tgcttctttt gaaaaagtca acccgtccat
    42661 gaaaggcatt tggatatcag tcagaatgat gtcgggctgt aagtcgataa ttgaagacag
    42721 tgccatctca ccatctccag cttcgccgac ataagtgatt ggataataag aaccaaggac
    42781 agttatttgt tcccgcaagt tattgcgaat gaggtattcg tcttcgatga taaaaacttt
    42841 atacatgttt gtttcctcca attgttttgg gagatagagg gatcatcagt gtgacagttg
    42901 ttccttctcg gtatttgctg tcaatcgtga taggtttttg atcatttccg taataaagaa
    42961 ggagacgctt gtttacgttg taaagtccgt agccgatact gaaatctgaa tcgatccctt
    43021 tggctaactc tttacgtatt tctgccagtt tttctgcagg gatgccaatc ccgttgtcta
    43081 taactttgaa ttggatcatc tcatcaattt tgcatgtggt aatacgaata aatcctttgt
    43141 gacggacgta cttcgttcca tggtatacag cattttcaat caatggctgc aagatcattt
    43201 ttaaaataga aacaggaaaa agtgtttctg gtatatcgat cttatagtca agcatatggc
    43261 cgtatcttat ttttaagatg actagataat cattgatatg gctaatttct ttttcaagag
    43321 gaatccagtc ttgtcctttg cttaaagacg tacgaaaaaa gccggaaagt gcatgggtca
    43381 tagtcagagc ttcttcaaag cagtcttgtt cgatcaaaga aataatggca tccaaactgt
    43441 tataaataaa atggggagta atctgagctt gcaatacacg aacttcactt tgtgctaaat
    43501 ggtattgttt caaagcgttc tcccgtaaag actggtttag atcttccgcc attttattca
    43561 tgctagcggt aagtgtttgt aattccagtg tttccggcag ggttaaacga aagccaaggt
    43621 tccctgaaga aagttgttct gacatctcga tcagctgatt gatcggttct tggacctttc
    43681 tctctaaaaa gcgacgattc tttttcgcat agaaaaaaat ggtactaaga actccaagtt
    43741 ccactattgt taatagaatg agcgagcgga caagtgtcgt attttttttg cttgctaagt
    43801 cgatctccac acgaacaaaa tcttgtaaga tatctgacag cagttgagtg acagaatcta
    43861 cctgattgat gatctcttca ttggtatcca taaaatcttt tgccaagata ttattgatca
    43921 gctcgttttg ataatcttcc agtgtatcga tcgtacgtag cgatacatct aacgtactaa
    43981 tttctttaag tgtatttgta ttatttttgc tctctcgaat atcattccta agttcttcta
    44041 ggatattttc ctcattgaac tcatctacgg ttacttggcc agaaatcaag tcccacatac
    44101 tttccaaaac tttttgatca accttcaaag caattgcatc tgctttttgg atatttgcga
    44161 tcgtctgttg ataaatcaaa agctgttgcg aatataacag tatgctcagt agcaaaggga
    44221 taacagcaaa tagaagcatg gctttgtttg cttgggcaaa aatctgtttt atgcttaaat
    44281 tttttgtcat gatacttctc cagtcaataa tttctggttg ggatgttagc tatattctgc
    44341 tgggaaaaga cagtctcgga aataaaaata tctttaggta atgtttttcc tgtttgaata
    44401 tttccaaaat aacgagtaac ggtattggct acataccagc cgacatcagg tttacactcg
    44461 actacacaat tgacgattcc tgagcgtagc ttctcgatca tatcttcttg tccatcaata
    44521 gttacaatga tcaaatcttc tccaggtttg attgatgttt cttttatcgc agctaaagca
    44581 ccgtgagtca tttcatcact atggctgtat aatacatcga tttcggataa atcatttgtt
    44641 tctaaatatc gtttcatctg gtcttttcct ttcatccgaa taaaatcacc gacaattcgg
    44701 tgaacaatag tcatcggagg tttatggtcg atggttccat ctttttttag ggttggttta
    44761 cgattgattg attccaaaaa tccttcggag cgtagcttgg tcggtgtgga gttctctgaa
    44821 ccagcaagtt ctaggattct gatttcctgt ttctttgaat ttgtgaagtg attgctgaca
    44881 aataaacccg cccgatttcc ttctgctttg aaactggggc caatgtgggt gacgaaaagc
    44941 tcgggatcat tcgtttgaat atgtctgtcg acaagtatga cagggatccc tgctcgcttt
    45001 gcttctttta atacagagtc ccacccggat tcttgcaaag gagtaaaaat gatcatatcc
    45061 actttatagg caatgaacgt ccgtatatct tggatttgcc gttcctgatt catgtagcca
    45121 tttcggtaga gaacttggta atcttctttt tcaagcgcag tgataattga ttcagtatgc
    45181 tttttccgcc agctactctc cgttcctgat tgcgaaaaac caacgactag tgggtcaggt
    45241 gcttcctttg tattaggtgt acaccccatc atttggtaag cgattacaac aagggctaaa
    45301 aaaaataaaa cacgtttcac tttaaatcac tccatctgga tttgttagta ctatcttatc
    45361 agataaaagg gaaaatcaaa gtcaaaagga atcaatcgaa aaaaatccaa gaaacttaaa
    45421 aaaatccaag acaaaaaaag tacacctaaa aaatttaaag taaatcccat aaaaaaatca
    45481 atgttaacgc tttctttatt agctatactc ggtgtatcaa ttgaaatggg ggataaaaaa
    45541 tgaaaaacaa atttagaaag attgttggga ctatcgctat tttgaccgca agcattctat
    45601 taagtgcgtg tggcaattca ggatctgcag atgatagtac ggggtatgta ggaatcgcta
    45661 tgccgaccaa atcagcagaa agatggatcg ctgatgggaa caacatggtc tcggaattag
    45721 aaaaactggg ttataaaaca gatcttcaat atggagaaga taaagtagaa aatcaagtag
    45781 cacaaataga aaatatgatt acaaaagggg tagatacact tgtgattgct tctatcgatg
    45841 gttcggcttt aactgatgtg ttagctaaag caaaagaagc agatatcaag gtgatcgcct
    45901 atgatcgttt actgatgaat tcagaaaatg tcgattatta cgcgactttt gataattttg
    45961 gagtaggtgt atcgcaagca gcttatattg aagagcactt aggattgaaa gaaggaaaag
    46021 gaccattcac gattgaatta tttggtggct cgcctgacga caacaacgca ctaatcaatt
    46081 acaacggagt gatgtctgtt ttacaaccat atatggacaa cggtcagttg gtcgtgccat
    46141 ctggacagac gagtttcagt caaatcgcta cgcttcgctg ggatggttct acggcgcaag
    46201 caaggatgga taatctgtta agcgcaaatt atactgacca aacattggat gctgttttgt
    46261 cgccatatga tccaataagt ttaggaatca tttcgtcatt aaaaggcgtg gggtatggga
    46321 gtgaaagtaa acctttacct gtgattactg gacaagatgc gacagttgct ggcgttaaat
    46381 cgatcattgc cggggaacaa acacaaacga tctttaaaga cacacgtatc ttagcaaaaa
    46441 atacgattga aatgatcaaa gcaatcagtg atggagaaga ggttccggtc aatgatactg
    46501 aaacttatga taatggggtg aaaactgtcc ctacgtattt agcaaataca gtatctgtcg
    46561 ataaagataa ttatcaagca gagctgatcg acaccgatta ttataaagaa tccgatctga
    46621 aaaattaaga ggaaccaaac aaggaactaa agagatctaa gtcagagaga ggataagaat
    46681 tatggcggat tgtattttaa aaatggcaga tatcaccaaa aaattttctg gaatccgagc
    46741 gttagattgc gtgaatctga tgattgaacg tggggaaatc catgcattgt gcggagaaaa
    46801 cggagcggga aaatcaacat tgatgaatgt cttgagcggc ttgtatccat atggctccta
    46861 tgacggggaa atcttttatg atggaaagct gtgtcaattt aaagatttga aagatagtga
    46921 agaaaaaggc atcgtcatca ttcatcaaga attagcacta agtccttatc tttcaataaa
    46981 agagaatatt tttctcggaa atgaacaagc agaaagaggc gtgattgatt gggaactgac
    47041 agaaaagaaa acatatgaac tgctgaataa agtcggtttg tctatcgacc cgaatcttct
    47101 agtatcccag attggcgtag ggcaacagca actagttgaa atagctaaag cattatcaaa
    47161 atccgtccgt ctgttgattt tggatgagcc taccgctgca ttgaatgaag aagaaagcgc
    47221 gaatttgctg agattgatcc gagagttgaa agagcaaggt gtaacctcca tcattatttc
    47281 acataagctg aatgaaatcg tggatatcgc agatcgaatc accattttac gggatggaca
    47341 gacgattgag acactagaaa atgaaatgat cagcgaagag catattattc gcggaatggt
    47401 gggcagagat ttagttgatc gttatcctga aagaaaaccg gatattggag aagtttattt
    47461 taaagtagaa gactggacgg tctatcaccc tcttgatcac gagcgaatca taaacgacca
    47521 catcaacttg catttgaaaa aaggagagat tgtaggaata gctggactga tgggagcggg
    47581 cagaactgaa ttcgctatga gtctatttgg acattcttat ggaagcaaga tatccggacg
    47641 tatattaaag gaaggggcag agatatcagt taagaccgtt ccttcagcca ttgcaaacgg
    47701 actcgcttat gtctcggagg accgaaaatc tttaggactg aatctgctga tggatattcg
    47761 ggaaaacgtg acgctgagca gtttggataa aataagtcaa aaaggagtat tagataaaga
    47821 aaaagaagta actgaggcag aaaatttccg gaaaaagatg cgtataaaaa caaactccat
    47881 ccatcaaatt gtcagtagtc ttagtggtgg gaatcaacaa aaagtcgttt tatccaagtg
    47941 gctgatgaca caacccgata ttcttttttt ggatgagcca acccgtggga tagatgttgg
    48001 ggcaaaatat gagatctaca cgattatcga agaaatggca gcaaatggca aagctgtctg
    48061 tcttatctct tctgaacttc ctgaaatatt agggatgtgt gatcgaatct atacgatgaa
    48121 cgaaggacgt attacaggag aagtctcgcg agaagatgca gatcaggaag tcttgatgaa
    48181 attaatgacg aaagaagagg tgggttaagt tggaacaggc aaaaaatctt acggataaaa
    48241 aagagaaaaa actaaatttg aaaagtagag cagctgatct ttttggtcgc tacagcatgg
    48301 tgatcatttt agcgggacta cttattgcgt ttcaattgat gacggatggt attttctggc
    48361 gtccattgaa tataactaac cttgttctgc aaaatagcca tatattagta ctagctgcag
    48421 ggatgttatt agttgtgctc ttaggtcatg tggatttgtc ggtagggtca gtgatggcgt
    48481 ttgttggtgc aattgcgggc atgatgatgg tcaatcgcca aatgaacccg tggatgacag
    48541 ttatcgcatg tcttgcagta ggcgggctga tcggcgcatg gcaaggtttt tgggtagctt
    48601 atgcagggat accggcgttt atcgtgactt tagcaggatt gctgatgttt cgtggactga
    48661 cacaagttgt tctaggaggc caatctctag caccttttcc agctgttttc caaaaaatgt
    48721 ctacgggtta tttaccagac ttaagcgaag gaagcagcct tcacttcttg acattgattt
    48781 taggaatgat catcacgatc gtgttagttg ttggtcaatg gcgaacaaga aatcgtcgga
    48841 aaaatcattt atttgaagtg gaatctccaa cagctttctt ggtaaaggcg gtatttacag
    48901 cagtcgttgt actaggaata acttatatct ttgcctctta tcaagggtat ccgattattt
    48961 tgatcattct tggtttgatc gttgcagcat atgggttttt gacaaataaa acagtagcag
    49021 gtcgacagat ttatgcgacg ggcggaaatc gaaaagcggc tgaactatca gggatcaaaa
    49081 caaagcgaat cacgttctgg gtattcgtca acatgggagt catggcagct ttagctggat
    49141 tagttttagc tgctcgattg aatgcggcaa cacctcaagc aggtacatcg atggaactgg
    49201 atgcaatggc ggcagtatat tttggtggtg cttcgacttc cggcggcatt ggaacaatca
    49261 tgggtgcgat tgtcggtggc ttggtcatgg gtgtattgaa caatggcatg tcgattttag
    49321 gcgtcggggt agactggcag caggcaatca aaggattgat cttgctttta gccgttgtgc
    49381 tagacttgta taataagaaa aaacgaacaa cgtaggagaa cgccggttat tcagaaaaaa
    49441 gactgtgaca agacatttgt cacagtcttt ttttcgctaa aagcgaacat tcattgtttc
    49501 gtttgtatag actaaaaata atatatgttt ttttaccatt cgtataaatt ctctttttgc
    49561 tcttgatttt tttgcttaat tgagttaaat tacatagggc gctaaaaaaa gccttgatta
    49621 aattaataat gttcgtgttt tgctggatgt gaacatcagg aggataatgt aatgaaagta
    49681 tttgattacg aagatattca attaattcct aataaatgta tcgtaaatag ccgttctgaa
    49741 tgtgatacaa cggtcacatt aggtaaacat acattcaaaa tgccagtagt gcctgccaac
    49801 atgcagacga ttattgatga aacaatcgca gaattcttag cggaaaatgg ttatttctat
    49861 atcatgcatc ggtttgatga agcagctcga attccgttta tcaaaaaaat gaaaaagcgt
    49921 ggattgatta cctcgatcag tgttggcgtc aagaaagagg aatattcctt tatagagaag
    49981 ttggcagaag aatcgctaaa tcctgattat atcactatcg acatcgcgca tggacatgct
    50041 aactcagtta ttgatatgat tcagcatatt aaaaaatatt tgcctgaaac ttttgtgatt
    50101 gccggtaatg ttggtacacc ggaagccgtc cgtgaattgg aaaatgcggg cgcagatgca
    50161 acaaaagtcg ggattggtcc aggaaaagta tgtattacaa aaatcaagac aggctttggg
    50221 actggaggct ggcaactggc agctcttaga tggtgtgcga aagcagctcg caagccgatc
    50281 atcgctgacg gtgggatcag aacacatggc gatattgcaa aatctgtccg ttttggtgcg
    50341 acaatggtca tgattggttc attgtttgcc ggtcacgagg aatctcctgg cgaaacaaaa
    50401 gtcgaaaatg gaatcgtgta taaagaatac tttggttctg cttcagaatt ccaaaaaggc
    50461 gaaaaacgaa atgttgaagg aaagaaaatc tggatccaac acaaaggatc tttgaaagat
    50521 acactagtgg aaatgcaaca agaccttcaa tcatctattt cttatgctgg aggaagagat
    50581 ctggaagcca ttcgaaaagt tgactatgtc atcgtgaaaa attcgatttt taatggagac
    50641 acaatctaaa aaataaataa aatattagga tgttgtgaaa aagttgtcct gcattaagta
    50701 ataagaacag ccaaacaaaa atagttcttt atatgttttg tttggctgga attattatcg
    50761 cagatacaag cttttgaaca tcattattca gaataaggga ctgtgataag atttttgtca
    50821 cagtccctta tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg gtaaaatcaa
    50881 aagaaaaaat agacaataga aaagagaagc ttatgtggga aaaagtagag aaaaaacaag
    50941 gaccgattta tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac ggaaggatca
    51001 atcctggaag tcaacttgaa tcagaacgaa aactagggca actttttggt gtgaatcgtt
    51061 ccaccgttgt ccatgcattg gaagagctta gggagcttgg ggtactaacg agcaaacgtg
    51121 gcagcggatg gtttgttaat cagactgaat gggggaaatt cgctgttcca agaatcgatt
    51181 ggcggcaaat gatctctcct cgttatgagc agacggactg gtatgagcaa aaaataagag
    51241 aagcaaagca gatccaaaaa acatcgtttc ttgatttata cgctagcgag atgccagatg
    51301 agcttttgcc gaattttgag tttccttctt attctcttga agaaatctta gcggaagaaa
    51361 aagaaatgga tcttttaggc tatactccgt tacgtaacaa aatcaaacgg tatttggaaa
    51421 gtaaatttga attggcattt tcccccaacc agcttcttgt gactggtggc ggtcagcaag
    51481 caatcttttt gattttacaa acgattcttt cagctggaga ggggatagct gtagagtcac
    51541 cttctttttt ttaccgatta cctcttttca aagcttcagg aacgcgttta tttgggatac
    51601 cgatggatga agaagggatc gacttagaaa aactgaaaga atcgatccat aaaaataaat
    51661 tgaaagcagt gcttatcaac ccgaattttc aaaaccctac aggaaaagtg atgagtcaaa
    51721 aacgacgaga aaagctagta gaattgtgtc gacagtatcg gcttccaatt attgaagacg
    51781 atgtatttac ggatctttca tttctaaacc aagaagaagt ccttcctata cgaacgattg
    51841 atccggataa tgtgttatac gtcggttcgt tatctagggt tttaggaaaa acaacgaaaa
    51901 tcggttgggt gataggacct gagactttta tctcgcaact agctcaagcg caagaaatga
    51961 tggagttttc gatgaatatc cttacacaaa tcacagtggc taatgtattt aatgaagcaa
    52021 ttgatttgaa aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga ctgataagcg
    52081 cttggggaga ttcacaatcg tttttcaagc ttcattcaat tttaggtggt tactatgcct
    52141 ggattacttg ggatgggaaa aaactagacc ccgaactagc agaaaaagta gtagatatgg
    52201 gtcttggaat tgcaccaagt ctactttttg ggcaagatat aaatggaatc agaatcaatt
    52261 acagtaggct ggatgaaaac caaataccgt tgttttattc aaagatgaaa attctagaaa
    52321 agtggttaac agaataattt cacaaagtaa atagattaaa gaatataaca gcttggattt
    52381 aaatttcaag ctgtttcttt tttttcggaa aaagaatacg atataaagaa actaagaaaa
    52441 aaccattatt tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg caacaaaact
    52501 gtataacacc aacgttttta aatagaaaca gatggttgta agtttgatta gaaaatagaa
    52561 aaaatgcaga tgaaatataa aacgctttcc ttattgtgat tttattcact aatgctgtta
    52621 atatgcggat tggcataatt tcctttcatc gtgaaaattt gtgcttttag cttgtgtttc
    52681 tcataaatcc atgataattt attaatgaag acggttaaat agtgatacag ttttattcac
    52741 tgtttcaatc gcagaatgaa gagattttct tatagatgag agaggaatgt gtgacaaatg
    52801 gcaaacaaaa aagcaccgat cgacttccaa gcactgctag atgaagtcaa tgcagatttc
    52861 ccagtatatc aagcacttga tcaagatgga aacgtagtta acaaagattt agtacctgat
    52921 ttatccgatg atgaactcgt tgaattaatg actcatatgg tatggtctcg tgtattagac
    52981 caacgttcaa cagcgctgaa ccgccaagga cgcctaggct tttttgcacc aactgctgga
    53041 caagaggcaa gtcagctggc tagtgcttac gcatttgata aagaagatgt tcttcttcca
    53101 ggttatcggg atgtacctca actagtaaaa catggtttac ctttatctca agctttttta
    53161 tggtctcgag gacatgctgc aggtaattct tatccggaag aattgaaagc tctaccacca
    53221 caaattatca tcggtgcaca atatgtacaa gcagccggtg ttgcattagg tttgaagaaa
    53281 cgaaacaaga aaaatgtcgt cttcacttat actggtgatg gcggttcatc acaaggtgat
    53341 ttttacgaag caatcaattt cgctggcgct taccatgcaa atgccgtatt ttatatccaa
    53401 aacaacgggt atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa aacacttgca
    53461 caaaaagctg tcgcagctgg gattcctggt attcaagtcg atggaatgga tccgcttgca
    53521 gtatatactg tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg accagtccta
    53581 atcgaaacac tgacttatcg ttatggacca catacactat ctggtgacga tccaacccgc
    53641 taccgtacaa aagacacaga tgacgattgg cagaaaaaag atccattgat ccgcttccgt
    53701 aaatatttga cggaaaaagg actttggtct gaagaaaaag aagaacaagt catcgaagca
    53761 actaaagaag aaatcaaagc agctattgct gaagccgaca aagtaccaaa acaaaaggtt
    53821 tcagatttct tgaaaaacat gttcgaagta tctccacaat caatcaaaga acaaattgca
    53881 atttatgaag cgaaggagtc gaaataatca tggcacaaaa aacaatgatc caagcaatca
    53941 cagatgcctt agcacttgaa ctagaaaatg acgagaatgt cgttgttttt ggtgaagatg
    54001 ttgggaaaaa cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag ttcggagaag
    54061 accgagtatt cgatactcct ttagctgaat ctggaatcgc aggattgagt ttcggtcttg
    54121 cgttagaagg atttcgtcca gttcctgaaa tccaattctt tggttttatt ttcgaagcaa
    54181 tggacgaagt agtagctcaa atggctcgta caagatatcg aatgagcggc actagaaatc
    54241 tacccatcac aattcgttcg ccatttggtg gcggtgttca tacaccagaa ttgcattcgg
    54301 ataatttaga aggtttgatc gctcagtctc ctggtattcg agtagtgatt ccttccaacc
    54361 cttatgatgc aaaaggacta ttgatttctt ctattagaag taacgatccg gttgttttcc
    54421 tagaacacat gaaactatat cgctcattcc gagaagaagt gccggatgaa gcttacgaag
    54481 ttcctttgga taaagcagca gttactcgtg agggaacaga tgtatctatt atcacatacg
    54541 gagcaatggt gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa aatatatctg
    54601 ttgaaatcat tgatcttcgt acagttgcgc cattagatgt agaaacgatc attcaatccg
    54661 tggaaaaaac tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg ggcgttgccg
    54721 cgcaagtagt ttctgagatc tcagaacgcg ctatcctttc attagaagcc ccaatcggac
    54781 gagtttctgc acctgataca gtcttcccat ttggacaagc agaaaatgtc tggttgccaa
    54841 atgcaaaaga tatcgaagac aaagtaaaag aaatcgcgga attttaagaa aagaagggac
    54901 gaaacaaagt catggcttat caatttaaat tgccggatat cggtgaagga atcgcagaag
    54961 gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat gatacattac
    55021 tagaagttca aaatgacaaa tcagtagaag aaatcccgtc acctgttaca ggaacggtta
    55081 aaaatgtgat tgttccagaa ggtaccgtag caaatgttgg ggatgtatta gtagaaatcg
    55141 atgcaccagg acacgaagac aatgaagggg acagtggtgt agccgcagaa tcccaaactc
    55201 cagctaaacc ggctgctgaa cccactgttg atacagaatc agctggatcg tcaagcgaag
    55261 gagtcttcca atttaagtta ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca
    55321 aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta gaagttcaaa
    55381 atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa aacgtgattg
    55441 ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat gctcctggac
    55501 acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa aaagtggaaa
    55561 catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta ttggctatgc
    55621 catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta actgcaactg
    55681 gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt ggtccaagca
    55741 gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca gctcctgcag
    55801 cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga gacttggaag
    55861 aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc aacagtaagc
    55921 atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta tgggataatc
    55981 ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc ttgccatatg
    56041 tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca tctatcgacg
    56101 atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca actgatacgg
    56161 atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg tttgctattg
    56221 cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct gcagaagata
    56281 tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt tggtttacac
    56341 cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca caacaaccaa
    56401 tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca ttaagtttcg
    56461 atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc aaacgtcttt
    56521 tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt tggagatttt
    56581 gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt agctgccatc
    56641 cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat tggcggtgtt
    56701 tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca ccattatcaa
    56761 gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact agattttgca
    56821 aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg tgttggtttc
    56881 ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt agatgatcac
    56941 acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa cgcaatcatc
    57001 gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg tgtgttagat
    57061 tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat cggtggcggt
    57121 gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt aacgattctt
    57181 gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt agtagaagat
    57241 gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga agcagtcgat
    57301 aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc cgttactgct
    57361 gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg cttagaacaa
    57421 gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg acgtacgaac
    57481 gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc acacaaagcc
    57541 agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc tgtagattat
    57601 aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg tatgacgatc
    57661 aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt ttcagggaac
    57721 ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac gacgatcgaa
    57781 gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat ggtctctgaa
    57841 ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac gattcatcct
    57901 catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg tttaccaatc
    57961 catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc gttttgtttt
    58021 ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc ttggtttatt
    58081 accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag atgcaagaat
    58141 atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta atgaagatgt
    58201 gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt ttgaagactt
    58261 atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg ggacgggaat
    58321 ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa aaaaatccaa
    58381 acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc atatcaagtc
    58441 ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa caatctcgca
    58501 aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga attttctaat
    58561 cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag aagggtgtaa
    58621 tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg gcaccttgaa
    58681 ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat ccggcgttgg
    58741 aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg gaaaaggaat
    58801 aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct tatcggaagg
    58861 cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc gagaaattgc
    58921 ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag tggcaatctt
    58981 gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg cagcgggaaa
    59041 tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc ctttgacatt
    59101 tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa tcgcagacct
    59161 tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat aaaaacgagc
    59221 aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga aaaaagtctg
    59281 ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa aaaggagtta
    59341 gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca cgttgaccac
    59401 ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga cgcacatacg
    59461 caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg tatcacgatt
    59521 ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat ggatactcca
    59581 ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga cggcgttgtg
    59641 ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt gaaaaaagca
    59701 ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc ttctgctcgt
    59761 cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc agatgatgat
    59821 cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag cttgtcagat
    59881 gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat tgaaaaaatc
    59941 cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt acttgactac
    60001 aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat caaagtagga
    60061 gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt aacgaaatta
    60121 tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg agacttgatt
    60181 gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt ggatcatcaa
    60241 gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt cttagttaat
    60301 aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat tgaagaacgt
    60361 ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa ctctccagat
    60421 gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga aaacatgcgc
    60481 cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga aatcgacggt
    60541 gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata tatgggtagt
    60601 gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca tacaggaaac
    60661 ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta ttcaactgaa
    60721 ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca atatctgcca
    60781 atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat cgatacagga
    60841 aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt cgtagaacca
    60901 ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa tgatttgact
    60961 gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa agaccaaaca
    61021 tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt cttgaatgat
    61081 gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat tttagagaaa
    61141 aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg aagagagaaa
    61201 ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc tgtggagaag
    61261 tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta aaagactttt
    61321 aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca cgaaaggaga
    61381 tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc gggaagatga
    61441 acgacttatt aaaacaatac tttggctatg atgagtttag acctggtcaa aaagaaatta
    61501 tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga agtgggaaat
    61561 caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt gtgtcccctt
    61621 taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata cccgccactt
    61681 ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa atcgatagac
    61741 agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat tttatccaag
    61801 caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt atctctcagt
    61861 gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat caactgccaa
    61921 atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct gctgacataa
    61981 aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa cgagaaaatc
    62041 tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa tatttaaaga
    62101 tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta gaccgtctct
    62161 atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt ctaaatgaga
    62221 atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg attgtagcga
    62281 caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc cattatcaaa
    62341 ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga gatggtcttt
    62401 ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag ttttttatcc
    62461 agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta aaagcgatga
    62521 cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat tttggcgaga
    62581 caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata gtagaagtaa
    62641 cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac tatggtaaac
    62701 aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct ttaggttttg
    62761 gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg atgcagttaa
    62821 ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat cctgttttga
    62881 aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat cgaaaggaac
    62941 ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa gtgctgcggg
    63001 aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta ttttcagatt
    63061 ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg cttcagataa
    63121 aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct cggataaaaa
    63181 atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat gaataaaaac
    63241 aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat aattaaggaa
    63301 ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga tccaagtatt
    63361 aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca gtctctgtat
    63421 ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct tttcccggca
    63481 agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc tgatgttaag
    63541 tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa tttatgataa
    63601 aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag gcatctatta
    63661 gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat catggtatat
    63721 agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc agtcattaac
    63781 cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa aatgaaaaca
    63841 gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac gattttgctg
    63901 ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct gcaaattgca
    63961 ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta cctgtctctg
    64021 actttatcta aaagacaaaa cagtgtacaa aaagattttc ttgggactgt gaaacgtcca
    64081 cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt tggtaatgcg
    64141 gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa ttatgtgtat
    64201 actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg gctgatcaat
    64261 atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg atttgctatt
    64321 taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa cggctactat
    64381 gccatgttca acggaggact atttggcagg ggattaggta acagtatcca gaaaaaagga
    64441 tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga actgggagtg
    64501 attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat tgtccttgta
    64561 ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg cgcaatgttt
    64621 ttgatccaag tatttgtcaa tcttggaggg attactggcg ttattccttt gacagggatc
    64681 acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat ttgtgtcggc
    64741 tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata ataaaaaaag
    64801 atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa tcgctgtacg
    64861 tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg cagaagaaga
    64921 tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac aaggaaaaaa
    64981 accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag aatgcggagc
    65041 tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg cgcaacggtg
    65101 cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata tttttggaga
    65161 taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc caggcacaga
    65221 tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg gttatccgat
    65281 tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc acgatgaaaa
    65341 gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct ttggtagtga
    65401 tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac agattctcgg
    65461 ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc agcgccgtca
    65521 ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac gtcaaaaaat
    65581 ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag gtacagtaga
    65641 atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg tccaagtgga
    65701 acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac tgttgattgc
    65761 tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa ttaaattaaa
    65821 tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact ttttaccaga
    65881 cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc tggatgtcgg
    65941 aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag taaaagtatg
    66001 tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct tgaaagaatt
    66061 tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca cacatcctga
    66121 attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat tatttgaatt
    66181 tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa ttactgtgaa
    66241 tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac gtatgcctaa
    66301 agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg cgaagggtgc
    66361 cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg atacgacatt
    66421 tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt tcaagcagat
    66481 tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt gggggggagc
    66541 aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt tgagaaaaat
    66601 tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa atgccgttgg
    66661 gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag cagcgcaagg
    66721 aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg aaaaaagtat
    66781 ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata ctggcgatat
    66841 caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg caaaggaact
    66901 agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc ttaaaccgca
    66961 ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa tccatctgca
    67021 tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa aagcaggagt
    67081 agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc ctagcatgag
    67141 cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga ttgaaaatgc
    67201 acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt ttgaaaacgg
    67261 cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac agtattcgaa
    67321 tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa tcaaacaaat
    67381 gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat catctaaagt
    67441 agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag atatttatga
    67501 aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag gagaactagg
    67561 gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag gcagacctgc
    67621 attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag taaaaaaaga
    67681 attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct atttgatgta
    67741 tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg ttacattact
    67801 ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg tacaaatcga
    67861 acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata tcgaagggaa
    67921 tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca aagataattc
    67981 gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag aacaaattgg
    68041 agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata acgttaaaaa
    68101 aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg aagcacgttt
    68161 tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt ctggtgacct
    68221 tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa aagactgggt
    68281 ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc agtcttgttt
    68341 ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca aatgacaacg
    68401 tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa accgatcgat
    68461 cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt tggttttgaa
    68521 acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat ccaagacagc
    68581 agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc gttttattta
    68641 gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt cacttttgag
    68701 taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta tcgtccgcta
    68761 attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac aaacggccta
    68821 ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata tcaagtgttt
    68881 ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc aatcaatcgc
    68941 gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga cgaacttccc
    69001 atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca tgattttttg
    69061 acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa atcgctaggc
    69121 agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa gttaatcagt
    69181 aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga cgctactttt
    69241 tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga cccgggaacg
    69301 gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca agaagaaaac
    69361 ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg aggatcaatg
    69421 cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc ttgaacataa
    69481 acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct tgtctaagaa
    69541 agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc gtgaaaaaaa
    69601 acgagctgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg cagctttccg
    69661 atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac ttgccgaaga
    69721 agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga aaaaacactt
    69781 tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata acaaaacgac
    69841 gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa aagttcggct
    69901 tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat gaagagacat
    69961 tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta gaacgttctt
    70021 accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca gtattaaaag
    70081 acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa catctttaaa
    70141 aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga tttttgatca
    70201 ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag tgagtagatg
    70261 cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg ggcgaacacc
    70321 agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc atattttgat
    70381 ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga agcagtatct
    70441 agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa aatcatcaaa
    70501 gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact tgatgcggac
    70561 aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt tcttgatccg
    70621 ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact gggacttttt
    70681 tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc agaaactgtg
    70741 gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac tatctataga
    70801 aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct tttacaaaag
    70861 gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta attggtgttt
    70921 ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca ttgatcacaa
    70981 aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa ttgacggtag
    71041 aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt atcaaagact
    71101 ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa ttggaaactg
    71161 tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta aaagaagtac
    71221 tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa gctttagctg
    71281 gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat tatcatattt
    71341 ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga atcaccggga
    71401 gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa aggttctggg
    71461 tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc tttaaaagct
    71521 aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg ggcgacaaat
    71581 gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc agcaatcgaa
    71641 caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt atatgtcatg
    71701 agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac agtaacaaaa
    71761 gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa aagccaaaaa
    71821 gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac agcttctggt
    71881 gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct tactgaccat
    71941 accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg tgggccatca
    72001 gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa cttgcgacat
    72061 ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg ccgaatcgga
    72121 ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt ctttgcacca
    72181 gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac caactacgaa
    72241 gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc agtaaaaaca
    72301 gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat taaagagggg
    72361 ttgtgacacg agttctgtca caacccctct ttttcgtcaa aaatcttcac gataaaaata
    72421 aaaacaaaag aaaaaattga cgtaattaga tgttgaaggg acgattttgc cagagctcac
    72481 tgtttcttca attttaaatg aaaggagtaa tgaatgattt ttactggtca ttctttgaaa
    72541 aaagaacaat gatagaaaaa atcagcaaga aaatactagc ttcacccaaa ttgatcattt
    72601 ggatgtctat gatagttctt atcttttgta tcgcaagtgg ttttttatta tcaaatttgc
    72661 tattttatag agaaacagaa gagactgctg caaaagaaat actttcttcg tttagttcca
    72721 gtggagaaga tccatcagct gaaggaaacg atgtagaaga ggatgctcgt ccaaaggtca
    72781 tgtacaccga tatcaaagga agtgtgaagg agcctggtat ctattccttt tcttcagaag
    72841 aacgggtcta tgatgtacta aagcgtgcag gtggattatt agaagaagcg gatagcgatc
    72901 gaatcaactt ttctgcgaag atagaagatc agcaagtcct atatatccct gctgtaggtg
    72961 aagagctgcc agaacatctt gatcagttgg catcctcgga aggaaaacag cctacagcag
    73021 attccgagcc tcccaaaata aatatcaata cagccactcc atcagaactt cagcagattc
    73081 ctgggatcgg atcagtcaaa gcgcaagaaa tcattcgatt tagagaagaa aacggatcct
    73141 tccagaaagt ggaagacctg caggagattt ctggtatcgg tgaaaagaca gttgaaaaac
    73201 taaaaaactt cgttacaatt aaatagaatg attcaaaatc gactggcacg agcaataaat
    73261 ggacgctaat ggatactaag aataatccaa ttctaagagc ttggcaggac gaggaggtag
    73321 tatttttgga taggaaatag cttgattgtt cgcaaagaaa cattaaaaaa accaatgctg
    73381 aatgtctatc tccaaaataa aatatctggg attcatatta tgaatacggc tgtcagcggc
    73441 aataacagtc aagctctacg agaacgcttt gccaaagatg tacttagcta tacagcagat
    73501 aaagtattta ttctcattgg gacgaatgat ctagcagagc ataaacaact ttctaaagaa
    73561 acgtaccaaa aaatctgcag tggatgatag ttcagctgaa aaaagactat agttctgatc
    73621 atgctttctt tatcacgcca ccagcagtcg atgagacaaa acaaaaatat cggaataaca
    73681 agttgatcaa agaatatatc tctgttctca cagaagtagc aaaacgccat gattgtgaag
    73741 tatcgatttt tatacggaat ttcttgaaca aatggattcg aagaattttt ataatgggct
    73801 aatggatgac ggacttcatt tcggcagtga agggtaggat cttttgtcag acaggatgat
    73861 tcgttatatt taaagaatat tttgtttaag caatgagtac tttttaatca acttgaaaaa
    73921 acggaggaat ataaaacatg ttagaaaaat cttcaaaagc atgcgatacg aataaagaaa
    73981 aagttactga taagtcacat aatgaacgca ttccttggga ccagtacttt atggctcagg
    74041 cagtactgtt atctttacgt agtacgtgta cacgtttaga agtaggagcg acactcgttc
    74101 gagaaaaaag gatcattgct ggcggctata atggagcagt cagtggagat gtccactgca
    74161 tagatgaagg gtgttacgtc gtggatggac actgcttgcg aacgatccat gcagagatga
    74221 atgcactcct acagtgtgca aaacttggta tcccgacgga aggttcagaa atctatgtca
    74281 cacattttcc atgtttggcc tgtacaaagg ctttgttgca agctggtgtg aaagggatca
    74341 attatctcca tgactatcga aatgatcctt atgcccaagc gttgatcgaa caattaggtg
    74401 tatctgtaca ccaagttgct ttagactcac agcatttttc aaaacttcaa aatgaattaa
    74461 caggaaaaca tgtctagcgt tttagaaagg catgttcgaa atcggttgat ttttccggca
    74521 attacgtcga tgattatctg tttgttgtat tacactgaca attggggtta tcgtttgctt
    74581 cttgccggaa tttttttatg gttttcgcta aaagaaggac gttttatcgc gtacttgtgt
    74641 attttgtgta gcataacggt atccatttct tataggctac aagagtattc atttttagag
    74701 gaaaaaacaa catctgcgca aattactgta tttacagata cgattcgtgc aaatggtaat
    74761 tttttgacaa tggaaggaag gttatcagag aataaacaaa agctccagct ttcttatcaa
    74821 gtaaacacag aagcagaatt gaaaacatgg cttaacttcc gaggaaaggg aatagaattg
    74881 actgctgaag gcgagttcat ctctccagca aaaaagcgga atctttataa ttttgaccaa
    74941 gaagcttact tcaggaacca tagaatttct ggacggttcc aaattcaaaa gattgaacag
    75001 atcaccatgc aaaatcactg gcgaaactgg cttcagagaa aaagaggatc ttttatctcc
    75061 tttgtccaat ctgaatttcc gcaaaaaaca agtgtatata ttaattcttt attatggggc
    75121 tataaagatg caggattcag agaaccagaa gaaattttta gggagagtgg tttgctgcat
    75181 ctgttcagtc tatcgggtct acacatccaa ttttatttag ggtggctgta ttatttattt
    75241 cgacgtatcg gatggccact acacgtcagt attattccgt tgagtctact aactatctgt
    75301 tatgtttcta ttgcaggaag ttctatttct gttttgcgtg ctagtttgct gtttttattg
    75361 cgattgctag tcaaattgct gaataagcat tattccacca tggacttatt tgcagttgtc
    75421 ttttggcttc ttttactatt tgatcctcga tttctttttc atgcgggtgg acagcttagt
    75481 tttttcatga gttttttgtt tatcctgatt tcttttgatg gagattggtt gaaaaaaacg
    75541 gcctctcacg tcctgtttac tatgatcacg atgccgttga ttgtatggca tttttatgag
    75601 tggcctattt taggtagtct ttttacatta ctgattgcac cggtattcaa gtttcttttt
    75661 cttcctggtg tgttatttct cacactcttc aatcgctggc tgccggaaac tttacttttg
    75721 ctgatagaag agggattaat cttatttgag cgaataatcg atttttcttc agggtcgtct
    75781 ctcattatag gacgtttgcc ccttgtgcta tctgggatgt atattttcgg attactgatt
    75841 tgtatggata ggttgaaaga acaacctgtg aaacacttgt tttatgttgg tcttttttct
    75901 tttatttttt tgactttgcc atttttacgc ttttcttcaa cgatcgcttt tatcgatgtc
    75961 ggtcaaggag acagtatctt tttgcaaagt ccttttcgaa aagaaacgat tttgatcgat
    76021 actggaggtc agttacactt tgaaagagaa aagtgggcgc aaggtatgat acgtcctcct
    76081 gctgaaagaa atatcgttcc atatctaaaa ggtcagggga taagtgtaat cgataaactc
    76141 atcttgacac acgacgatac ggatcatgtg ggagaattac ccacgttatc tcagcatttt
    76201 actatcaaaa aaatttatat cggttggggc gctggacgaa atgagccatt acaaaggcat
    76261 ttatctgaag ctcaaaaaaa tggtactgag atcattgaaa tcaaacatgg ggacaggatc
    76321 agcggttatt atgatcttta tgtattgact ccttttgaaa agggagaggg aagaaatgaa
    76381 gattcgattg gtctatggat ggaatataac aataggcgct ttttattttt aggagatttg
    76441 aatcaagcaa tggaaaaaca attgcttttg atttatccta atctgaaagc cgatgtagtc
    76501 aaattaggtc atcacggtag ccgtacgtca agtaacacag attttctttc ccatattgaa
    76561 gcaaaacatg ggattatatc ctgcggcgta aataatcgtt atggtcaccc gcacagcgaa
    76621 gtattggaga cactagaaga aaatcagata aaaacatggc gaacggatca acaaggaatg
    76681 atcacctatc gctggcatcc agtttttcat cctcatgggc tagtggaaac aatgatagac
    76741 tagtaattct catctgctca tggtaggata atttttgaaa gtggtgagta atttgagtat
    76801 acaagcagag ttacaaaaaa tacgtaaaga aaaacttgca tcttgttact tgattttagg
    76861 aacagaaaag tttctccaag atcaagttcg gacagaaatt gtcaaaaaaa tccaattaga
    76921 gggcgaagat gacttaaatt ttttaagttt tgacatggaa aatgcaagtt tagatgaggt
    76981 agtagctgaa gcagagacgt tgccgttttt cggagatcaa cggttagtat tcgtagagaa
    77041 tccttatttt ttaacaggtg aaaaagtaaa caatggaatc gaacaaaata ctgatttatt
    77101 gacggcttat ttgaaagaac cattagaatc gactgtatta gtattctttg cgccatatga
    77161 aaagttggat gaacggaaaa aagtaacgaa acaattgaaa aaaacagcaa ttatcatcaa
    77221 tgtccaacag ttgaatgaaa aagaagtacg tcaatatctg atgaatacct tagagaattc
    77281 ctcaatcaaa atggaacgaa gtgcaattga tttattcttg aggttgaccg acttagattt
    77341 atccaaaatg atgagagagt tacagaaatt ggtcctttat ggacaaaatc aacagcaaat
    77401 cacggtaaga gaagtagaag aattagttcc taaaacgtta gaacataata tttttgacat
    77461 gacccaatat attttaaaag ggaagacgga acaagctttg cgtttatacg aagatttagt
    77521 tatgcaaggg gaagaaacaa tcaaaattaa tgcgattttg ctttctcaat tacgtttatt
    77581 tttacagaca aaatttcttg taaagattgg ttatcagcag gcaaatattg ctgaaacatt
    77641 gaaaatccat ccatatcgtg taaaacttgc catgcaggaa gtaaaaaaat tcgatgaaca
    77701 tttgctggta cagttgtttg atcaattagt tgagatggat tatcaaatca aaacgggaca
    77761 aatcgaaaaa gaattaagtt ttcaactatt cgttttgcgc acagggcagt tgttaagaaa
    77821 tcgataagaa gaaagacgag ggcaaagcat gcgggaaggt cgtttgtttt tgtccttttt
    77881 ttgacaaata aaaaaatcgg ccgaagccga ttcttttatt tagcgatttt tttgcttaaa
    77941 cgagatttgt cgcggttagc tttgtttttg tggattagac cttttgattc agccatatca
    78001 atagctttaa cagcttcttt atataacgca tctacgttgt cagcacctga agctacagca
    78061 tcttcaaatt ttttgattgc agtacgcata gcgcttgttt gagatgaatt tttcacatta
    78121 gcgttttcgc ttgtacgaac acgtttgatt gcagattcaa tgtttggcat tagtttcacc
    78181 tccgataact taagttctta cgcgtgttac cgcataattc aacattcatt attataccta
    78241 aaggcagcgt gctttgcaat atgaacatga caagtttttt tccttaacag tcttttatta
    78301 ggattttttt tcagtaaaaa cggatagtac aagctgaaaa aaatcaaaaa gacgctattg
    78361 tgggaggcaa tagcgtcaaa ccaaactaga tttttattta tctatttaaa caaagtttga
    78421 atgggaatgt ttggtactaa gttattatat aacaaagaga accgtttgca aagttttttt
    78481 tgaaaaggga tacgattccc tgttgttctt tgtttttcta ttaagaaact gcagttattt
    78541 tataaccagt atcctttgat cagtaaaggc tattctggtg taccgattat tttaatgtat
    78601 tcatcgatat tttttatcaa catttttttt atgaccaact ggttccgacg gttccatttg
    78661 ccacttactt ccagcacata tttatttagg ggcaaacgta agatatattt tgccaaatag
    78721 cgatctttaa gcaggccatt gatcacacgg tcctcaagct gcaagttgat cccagtcagc
    78781 atcattggct gttcttgtaa aacgtacgta tcaattaaaa gaccttcaaa agtttccaca
    78841 agcgtcttcc tttcttttca aagtaacctg aaaacaggca ctaattcttc cattttgata
    78901 ttcgttgaag tggatgcgat cattctttct tttgtccact gtaatctagt ataacaaaaa
    78961 agagcagaag agccaaaaag aaaaaagagc atcgaattct ataggaagtc tcattggcac
    79021 ggcctaaatt attaca
//
LOCUS       DAXLPQ010000008        69786 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.008, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000008 DAXLPQ010000000
VERSION     DAXLPQ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 69786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.008"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(9..125)
                     /locus_tag="ACF3UO_000691"
     CDS             complement(9..125)
                     /locus_tag="ACF3UO_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFD3656742.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(198..1154)
                     /locus_tag="ACF3UO_000692"
     CDS             complement(198..1154)
                     /locus_tag="ACF3UO_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3656743.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1325..1693
                     /locus_tag="ACF3UO_000693"
     CDS             1325..1693
                     /locus_tag="ACF3UO_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFD3656744.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1863..2294
                     /gene="mraZ"
                     /locus_tag="ACF3UO_000694"
     CDS             1863..2294
                     /gene="mraZ"
                     /locus_tag="ACF3UO_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFD3656745.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            2315..3274
                     /gene="rsmH"
                     /locus_tag="ACF3UO_000695"
     CDS             2315..3274
                     /gene="rsmH"
                     /locus_tag="ACF3UO_000695"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFD3656746.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            3279..3680
                     /gene="ftsL"
                     /locus_tag="ACF3UO_000696"
     CDS             3279..3680
                     /gene="ftsL"
                     /locus_tag="ACF3UO_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFD3656747.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRRVK"
     gene            3681..5873
                     /locus_tag="ACF3UO_000697"
     CDS             3681..5873
                     /locus_tag="ACF3UO_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFD3656748.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5899..6861
                     /gene="mraY"
                     /locus_tag="ACF3UO_000698"
     CDS             5899..6861
                     /gene="mraY"
                     /locus_tag="ACF3UO_000698"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFD3656749.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6875..8236
                     /gene="murD"
                     /locus_tag="ACF3UO_000699"
     CDS             6875..8236
                     /gene="murD"
                     /locus_tag="ACF3UO_000699"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFD3656750.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            8262..9350
                     /gene="murG"
                     /locus_tag="ACF3UO_000700"
     CDS             8262..9350
                     /gene="murG"
                     /locus_tag="ACF3UO_000700"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFD3656751.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            9365..10585
                     /locus_tag="ACF3UO_000701"
     CDS             9365..10585
                     /locus_tag="ACF3UO_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFD3656752.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10741..12066
                     /gene="ftsA"
                     /locus_tag="ACF3UO_000702"
     CDS             10741..12066
                     /gene="ftsA"
                     /locus_tag="ACF3UO_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFD3656753.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            12089..13330
                     /gene="ftsZ"
                     /locus_tag="ACF3UO_000703"
     CDS             12089..13330
                     /gene="ftsZ"
                     /locus_tag="ACF3UO_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFD3656754.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            13347..14024
                     /locus_tag="ACF3UO_000704"
     CDS             13347..14024
                     /locus_tag="ACF3UO_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFD3656755.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            14038..14637
                     /locus_tag="ACF3UO_000705"
     CDS             14038..14637
                     /locus_tag="ACF3UO_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFD3656756.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14718..14939
                     /locus_tag="ACF3UO_000706"
     CDS             14718..14939
                     /locus_tag="ACF3UO_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFD3656757.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            14988..15770
                     /locus_tag="ACF3UO_000707"
     CDS             14988..15770
                     /locus_tag="ACF3UO_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFD3656758.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15791..16498
                     /locus_tag="ACF3UO_000708"
     CDS             15791..16498
                     /locus_tag="ACF3UO_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFD3656759.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDIGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16760..19558
                     /gene="ileS"
                     /locus_tag="ACF3UO_000709"
     CDS             16760..19558
                     /gene="ileS"
                     /locus_tag="ACF3UO_000709"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFD3656760.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19607..21133)
                     /gene="zwf"
                     /locus_tag="ACF3UO_000710"
     CDS             complement(19607..21133)
                     /gene="zwf"
                     /locus_tag="ACF3UO_000710"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFD3656761.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(21148..21795)
                     /locus_tag="ACF3UO_000711"
     CDS             complement(21148..21795)
                     /locus_tag="ACF3UO_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFD3656762.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(21979..22308)
                     /locus_tag="ACF3UO_000712"
     CDS             complement(21979..22308)
                     /locus_tag="ACF3UO_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFD3656763.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22485..23213
                     /gene="sfsA"
                     /locus_tag="ACF3UO_000713"
     CDS             22485..23213
                     /gene="sfsA"
                     /locus_tag="ACF3UO_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFD3656764.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            23229..24242
                     /locus_tag="ACF3UO_000714"
     CDS             23229..24242
                     /locus_tag="ACF3UO_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3656765.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            24242..25519
                     /locus_tag="ACF3UO_000715"
     CDS             24242..25519
                     /locus_tag="ACF3UO_000715"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3656766.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25582..28284
                     /locus_tag="ACF3UO_000716"
     CDS             25582..28284
                     /locus_tag="ACF3UO_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3656767.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28436..28753
                     /locus_tag="ACF3UO_000717"
     CDS             28436..28753
                     /locus_tag="ACF3UO_000717"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3656768.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28783..29103
                     /locus_tag="ACF3UO_000718"
     CDS             28783..29103
                     /locus_tag="ACF3UO_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3656769.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            29211..30671
                     /locus_tag="ACF3UO_000719"
     CDS             29211..30671
                     /locus_tag="ACF3UO_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3656770.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30739..30960
                     /locus_tag="ACF3UO_000720"
     CDS             30739..30960
                     /locus_tag="ACF3UO_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656771.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            30991..31173
                     /locus_tag="ACF3UO_000721"
     CDS             30991..31173
                     /locus_tag="ACF3UO_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFD3656772.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            31173..31586
                     /locus_tag="ACF3UO_000722"
     CDS             31173..31586
                     /locus_tag="ACF3UO_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFD3656773.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31709..32890
                     /locus_tag="ACF3UO_000723"
     CDS             31709..32890
                     /locus_tag="ACF3UO_000723"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3656774.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(32961..33125)
                     /locus_tag="ACF3UO_000724"
     CDS             complement(32961..33125)
                     /locus_tag="ACF3UO_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656775.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            33279..33352
                     /locus_tag="ACF3UO_000725"
     tRNA            33279..33352
                     /locus_tag="ACF3UO_000725"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33313..33315,aa:Arg,seq:cct)
     gene            complement(33421..34560)
                     /locus_tag="ACF3UO_000726"
     CDS             complement(33421..34560)
                     /locus_tag="ACF3UO_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3656776.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            34732..34866
                     /locus_tag="ACF3UO_000727"
     CDS             34732..34866
                     /locus_tag="ACF3UO_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656777.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(34859..35495)
                     /locus_tag="ACF3UO_000728"
                     /pseudo
     CDS             complement(34859..35495)
                     /locus_tag="ACF3UO_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35608..36243)
                     /locus_tag="ACF3UO_000729"
     CDS             complement(35608..36243)
                     /locus_tag="ACF3UO_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFD3656778.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(36277..36738)
                     /locus_tag="ACF3UO_000730"
     CDS             complement(36277..36738)
                     /locus_tag="ACF3UO_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFD3656779.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(36868..37299)
                     /locus_tag="ACF3UO_000731"
     CDS             complement(36868..37299)
                     /locus_tag="ACF3UO_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFD3656780.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDK
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(37317..37637)
                     /locus_tag="ACF3UO_000732"
     CDS             complement(37317..37637)
                     /locus_tag="ACF3UO_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3656781.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            37936..38712
                     /locus_tag="ACF3UO_000733"
     CDS             37936..38712
                     /locus_tag="ACF3UO_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFD3656782.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            38727..38930
                     /locus_tag="ACF3UO_000734"
     CDS             38727..38930
                     /locus_tag="ACF3UO_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656783.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            38946..39284
                     /locus_tag="ACF3UO_000735"
     CDS             38946..39284
                     /locus_tag="ACF3UO_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFD3656784.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            39271..39450
                     /locus_tag="ACF3UO_000736"
     CDS             39271..39450
                     /locus_tag="ACF3UO_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656785.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(39493..39963)
                     /locus_tag="ACF3UO_000737"
     CDS             complement(39493..39963)
                     /locus_tag="ACF3UO_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656786.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            40050..40748
                     /locus_tag="ACF3UO_000738"
     CDS             40050..40748
                     /locus_tag="ACF3UO_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFD3656787.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            40926..41267
                     /locus_tag="ACF3UO_000739"
     CDS             40926..41267
                     /locus_tag="ACF3UO_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656788.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            41260..41931
                     /locus_tag="ACF3UO_000740"
     CDS             41260..41931
                     /locus_tag="ACF3UO_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFD3656789.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            41937..42623
                     /locus_tag="ACF3UO_000741"
     CDS             41937..42623
                     /locus_tag="ACF3UO_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFD3656790.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            42626..43375
                     /locus_tag="ACF3UO_000742"
     CDS             42626..43375
                     /locus_tag="ACF3UO_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656791.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            43387..43656
                     /locus_tag="ACF3UO_000743"
     CDS             43387..43656
                     /locus_tag="ACF3UO_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656792.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            43661..43825
                     /locus_tag="ACF3UO_000744"
     CDS             43661..43825
                     /locus_tag="ACF3UO_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656793.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            43818..44120
                     /locus_tag="ACF3UO_000745"
     CDS             43818..44120
                     /locus_tag="ACF3UO_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656794.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            44117..44278
                     /locus_tag="ACF3UO_000746"
     CDS             44117..44278
                     /locus_tag="ACF3UO_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFD3656795.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            44275..44580
                     /locus_tag="ACF3UO_000747"
     CDS             44275..44580
                     /locus_tag="ACF3UO_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656796.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            44580..44936
                     /locus_tag="ACF3UO_000748"
     CDS             44580..44936
                     /locus_tag="ACF3UO_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFD3656797.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            44896..45141
                     /locus_tag="ACF3UO_000749"
     CDS             44896..45141
                     /locus_tag="ACF3UO_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656798.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            45138..45557
                     /locus_tag="ACF3UO_000750"
     CDS             45138..45557
                     /locus_tag="ACF3UO_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFD3656799.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            45554..46111
                     /locus_tag="ACF3UO_000751"
     CDS             45554..46111
                     /locus_tag="ACF3UO_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFD3656800.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            46108..46404
                     /locus_tag="ACF3UO_000752"
     CDS             46108..46404
                     /locus_tag="ACF3UO_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656801.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            46481..46894
                     /locus_tag="ACF3UO_000753"
     CDS             46481..46894
                     /locus_tag="ACF3UO_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFD3656802.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            47203..47355
                     /locus_tag="ACF3UO_000754"
     CDS             47203..47355
                     /locus_tag="ACF3UO_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656803.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(47352..47627)
                     /locus_tag="ACF3UO_000755"
     CDS             complement(47352..47627)
                     /locus_tag="ACF3UO_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656804.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            48081..48287
                     /locus_tag="ACF3UO_000756"
     CDS             48081..48287
                     /locus_tag="ACF3UO_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656805.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            48483..48650
                     /locus_tag="ACF3UO_000757"
     CDS             48483..48650
                     /locus_tag="ACF3UO_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFD3656806.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            48676..49020
                     /locus_tag="ACF3UO_000758"
     CDS             48676..49020
                     /locus_tag="ACF3UO_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFD3656807.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            49025..49306
                     /locus_tag="ACF3UO_000759"
     CDS             49025..49306
                     /locus_tag="ACF3UO_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656808.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            49409..49723
                     /locus_tag="ACF3UO_000760"
     CDS             49409..49723
                     /locus_tag="ACF3UO_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFD3656809.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            49701..51395
                     /locus_tag="ACF3UO_000761"
     CDS             49701..51395
                     /locus_tag="ACF3UO_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFD3656810.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            51415..52593
                     /locus_tag="ACF3UO_000762"
     CDS             51415..52593
                     /locus_tag="ACF3UO_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD3656811.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            52556..53242
                     /locus_tag="ACF3UO_000763"
     CDS             52556..53242
                     /locus_tag="ACF3UO_000763"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFD3656812.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            53242..54402
                     /locus_tag="ACF3UO_000764"
     CDS             53242..54402
                     /locus_tag="ACF3UO_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFD3656813.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            54412..55287
                     /locus_tag="ACF3UO_000765"
     CDS             54412..55287
                     /locus_tag="ACF3UO_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656814.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            55284..55595
                     /locus_tag="ACF3UO_000766"
     CDS             55284..55595
                     /locus_tag="ACF3UO_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656815.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            55585..55938
                     /locus_tag="ACF3UO_000767"
     CDS             55585..55938
                     /locus_tag="ACF3UO_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFD3656816.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            55928..56329
                     /locus_tag="ACF3UO_000768"
     CDS             55928..56329
                     /locus_tag="ACF3UO_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656817.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            56322..56726
                     /locus_tag="ACF3UO_000769"
     CDS             56322..56726
                     /locus_tag="ACF3UO_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656818.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            56738..57346
                     /locus_tag="ACF3UO_000770"
     CDS             56738..57346
                     /locus_tag="ACF3UO_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD3656819.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            57366..57728
                     /locus_tag="ACF3UO_000771"
     CDS             57366..57728
                     /locus_tag="ACF3UO_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656820.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            57731..57913
                     /locus_tag="ACF3UO_000772"
     CDS             57731..57913
                     /locus_tag="ACF3UO_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656821.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            57930..61361
                     /locus_tag="ACF3UO_000773"
     CDS             57930..61361
                     /locus_tag="ACF3UO_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFD3656822.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVKKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            61412..62149
                     /locus_tag="ACF3UO_000774"
     CDS             61412..62149
                     /locus_tag="ACF3UO_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD3656823.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            62159..64450
                     /locus_tag="ACF3UO_000775"
     CDS             62159..64450
                     /locus_tag="ACF3UO_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFD3656824.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            64474..66600
                     /locus_tag="ACF3UO_000776"
     CDS             64474..66600
                     /locus_tag="ACF3UO_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656825.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            66617..66766
                     /locus_tag="ACF3UO_000777"
     CDS             66617..66766
                     /locus_tag="ACF3UO_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656826.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            66763..67209
                     /locus_tag="ACF3UO_000778"
     CDS             66763..67209
                     /locus_tag="ACF3UO_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656827.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            67211..67348
                     /locus_tag="ACF3UO_000779"
     CDS             67211..67348
                     /locus_tag="ACF3UO_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFD3656828.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            67386..67679
                     /locus_tag="ACF3UO_000780"
     CDS             67386..67679
                     /locus_tag="ACF3UO_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656829.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            67676..67900
                     /locus_tag="ACF3UO_000781"
     CDS             67676..67900
                     /locus_tag="ACF3UO_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFD3656830.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            67897..68922
                     /locus_tag="ACF3UO_000782"
     CDS             67897..68922
                     /locus_tag="ACF3UO_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFD3656831.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNPYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            69112..69185
                     /locus_tag="ACF3UO_000783"
     tRNA            69112..69185
                     /locus_tag="ACF3UO_000783"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:69146..69148,aa:Ile,seq:cat)
BASE COUNT        23873 a        11309 c        14393 g        20211 t
ORIGIN      
        1 ttttattttt acatgacact cattacagca gtcaatacaa cagatccaat cgttaaaatc
       61 agcattgtcc aaatgacaaa ttttgttact ttagcaaaag tacttgtttg ttttttttca
      121 cgcattgttt tcaacctcgt cattaattag ttgattcaag tgtacaatct tttttccatt
      181 tccacaagag ggctttttta taaaaacttc ccttttttta aataataggt agttacgata
      241 caaataaata atgttaatag aactagccat ataaaggcat catccctttc agcaataggt
      301 aacttaatgt tcattccata gatactgccg acgattgtcg gtatagttaa aataatcgtt
      361 aaagaagtta aaattttcat aatattattc agattattcg atacgattgc tgaaaaagtc
      421 tgattcattt gttctactag ttttaattga atgcgagaag tagtcattgc ctgctctgtt
      481 tccaccaata catcacgtaa atgatttttc aaagcatgat tttcttggaa aagtttattt
      541 tgcgctagtt ctttcaatgc atctaaatta gcagaagtcg cttctctgaa ataaacgagg
      601 cttttttgga tatccatgat ttgataaagt tgtttgtttt cagtggatac ttgaagtttg
      661 gcttccaaag tatcgcattg agattgaagc gtagctaaat aactgttgta agagagtgtg
      721 acctgccaaa tgaattgaaa gaagatattg agattaggcg aaatatcact ttttggaaag
      781 gtctggctaa agactttctt taaaaacagt ggttcatgat tcgtaattgt gataagcttc
      841 tttttgggcg tcaaaataat agagagcggg tatgtatcca cttgaaaata accgctagga
      901 cttgttttag caaaaggata ttgtaacaat aataacgctg gctttgtcaa ctttgattga
      961 ttgaattctt ctgtacggga attttctgca tcgtccaata tggaagtgat gtaatctgac
     1021 ggaatttcaa attgatgtgt cagctgatga atctcttctt gattaggacg ttctacacaa
     1081 taccagatcg tttggtcagt ttcctttccg gtattacgca gtttctcatt atctaatgta
     1141 aaatatttga tcatgatttt cctcctgttg cctgtttctt ttattataac ggatagggaa
     1201 ttggaataca tggaatgtgt ttgtaagata tagaatataa ctgcataaat ttaaataaaa
     1261 tgaaacagtt gtgtaaagta tatacagtat acttgaagca acgataaaaa aggagtttac
     1321 gttcatgggc acattcacac cacttatctt gttttggtat atttacccgg taatcgtttt
     1381 gtttggttgc caatttcttg taaaattatt ttcgttaaat cgtcgtttta aaataaaagc
     1441 ccctgatttg gcgattcctt ttttgtgggg cggtatgcat gcattgtcta gaaatacagg
     1501 gacaatttct atcttaccgt ttttctttat ttctgttttg ctaatgggaa tttgtattgc
     1561 tgttttccaa gcatattatt atgaagaaat tatttatccg cgttatttca agatgacttg
     1621 gcgtttggtt tttctgttga caatcgtctt gtacgctgtc ttgatcattg tgaacatact
     1681 ttcttaccta tgaaaaaaat agaaaagctg taaaaagtct tttaaaaggc tttttgcagc
     1741 ttgattttta aaaaaatgtt tatgaataaa aaaagttgtt cccggatttc ccagaaaagg
     1801 tggtagaaag tgggggattg tggtagacta attttagtta gtggaggaat ggggggcttt
     1861 caatgttgat gggtgaattc caacataata ttgatgcaaa aggacgttta atcgtgccct
     1921 caaaacttcg tgaagaactt ggcgaaaagt ttgttctgac acgcggattg gatggctgtc
     1981 ttttcggcta tccgatgagc gaatgggaaa atctggaagc taaactgaac gaaatgccgt
     2041 tggctaaaaa agacgcacgt acttttgtgc gattcttcta ttcggctgcc actgaatgcg
     2101 aacttgataa acaaggacga atcaatatac ccagcacgtt aagaaattat gcagctttga
     2161 caaaaggttg cgtagtcatc ggtgtatcta accgaattga aatttgggat gagacacgat
     2221 ggcaagattt ttctgcagca gcagaagaga actttgacga aattgctgaa agtatgattg
     2281 atttcggact ataagaatag gaagaggctg actaatgact gaaacatttc aacactatac
     2341 agtcatgttg aaagaaacgg tagatggatt gaacatcaaa ccggatggcg tttatgtaga
     2401 ctgtacactc ggcggtgccg gacatagtga atatttatta agccaactaa gttctaaagg
     2461 gcatctgtat gcgtttgacc aagatcaaaa agcaatcgat cacgccaagc tgcgtttagc
     2521 ttcttatgtc gaacaaggta tggtcacatt tatcaaagcg aacttcagag aattagaaga
     2581 acgcttgagt gagcatgtag ataaggtaga cggcattttg tatgatctag gggtttcctc
     2641 tcctcagcta gatgaagcag aacgtggatt tagttatcat caagatgcac cgttggatat
     2701 gcgcatggat cagtcagctc ctttatccgc ttatcacgta attaatgaat attcctacca
     2761 tgaattagta aagattttct tccgctatgg cgaggagaaa ttttccaaac aaattgctcg
     2821 tgaaatcgaa cgagtacgaa aaacaaaacc aatccaaaca actggtgagc ttgtcgaaat
     2881 cattaaacaa gtcatcccag ctcccgcaag aagaaaaggc gggcatcctg caaaaagaat
     2941 ttttcaagct gtgcggattg cagtaaatga cgaactcggt gccgaagagg cctctttaga
     3001 acaggcaatc cggttattga aagtcaatgg aagaatcagc gtaatcacat tccattcatt
     3061 ggaagacaga attgtcaaaa gtatgtttaa agaatatagt acggtacaag atctaccacc
     3121 gggacttcct gtcatacctg acgaattcca accagaactg aaagtcatta ctcgtaaacc
     3181 aatccttcct tcagaggaag agctaacaga aaacaatcga tcacgcagtg caaagttacg
     3241 tattgcagaa aaaataagaa tgaaagagga gtagaatgat ggcagaatta aagaaaatgc
     3301 aagattacga atatgattta cctgaattgg tggatcagcc ggaacaacaa atgcctgatt
     3361 cttcttcgaa tcaagaaatc attcttccac aatcaccggc aaaacgatta aagcagattt
     3421 ctgctttgga aaaaattgct gtggcaagcg tggcgattgc tattgttgct ttatgtgttt
     3481 taacagttat gctgcgcaca aatatcagcg gagctgaaaa agaaatcacg tcaatacaaa
     3541 cagaaatcaa tgataaaaag caagaaaaaa cgagtttaga acaagaaaaa aacgaacttt
     3601 ctcgtactga acggattaaa caaatcgcag aagaaaaagg attgtctatt aatgacgaca
     3661 atttaaggag agtgaagtaa atgagtctta aaaataaaat tcggcggttt atggaaaaga
     3721 aaaatctaaa tccgatgaac aatcgcaaaa aagtaggtat cattttattt gctacgagta
     3781 ttggattgtt ctttttattt gccgtccgtt tctcgtatat cgttattgga ggtcatgttg
     3841 ctggtacctc attagctgaa aaaacaaaac agttgtacca aggaagtgaa gtagtaaaag
     3901 caaaaagagg aacgatttat gatcgtaacg gtgtggcgct cgcagaagat gcctcctctt
     3961 attcaattaa agcgatactc tcaaaaacat atacctctgg ggataaaaaa ctgtatgttg
     4021 aagaaaagaa ttttgataaa atagcagaaa tcctgcataa gaatctttct atagacaaaa
     4081 aagatgcact gaatatttta gaggacggcg caaaaaaaga gctgtatcaa gttgaatttg
     4141 gtagctatgg gaaaaatatc tcccaagaaa ccaagcaaaa catcgaagcg gacatgaaaa
     4201 aagaaggtgt cgctggtctt tattttgtcg accatcaggc tcggatgtat ccaaatggcg
     4261 tcttttcttc tcattttatt ggatacgcag ttccagacaa agatgagaat ggcttagttg
     4321 gtaaactagg tttggagtct gcttacaatg atatcttgag cggtaaagat ggtaagatta
     4381 tttatcaaaa agataatttt caaaatcctc tgccaggtac agtggcagaa gaagaaaaag
     4441 ctgtcgacgg acaagatatc tacacgactt tagacagcag actacaaagt tatttagaaa
     4501 cactgatgga tcaagtaaat gaagaatatc agccagaaga attgacagca gtcctgatga
     4561 aagcaaaaac cggagaaatc ttggcaatgg gacaacgacc tactttcaat cctgaaacaa
     4621 tggaaggatt gactggaaaa gatgctatct ggcgtaattt cttggtacaa gatagttatg
     4681 aaccaggatc aaccatgaaa gttttcacta ctgcagctgc tatcgaagaa ggagaattca
     4741 acgagaatga aaccttccaa tctggaaaaa tccaagtaga agatgctacg atcaatgacc
     4801 atgactttgg tgaaaaaggt gtgctgacca tgcgtcaagc tctttcatgg tcaagtaacg
     4861 tcgggatggt catactggaa cagcgattag gcggacgatg gtataactat ttacaaaaac
     4921 tgggatttgg acaaagtact cattctggat tagatgatga agtaaacggt gctttaccta
     4981 cattaaatat tgtcgaccga gcaatgagtg cttatggaca agcggtaggt gtgacgaatt
     5041 tccaaatgat gaaagctttc acttctattg cgaataacgg tacaatgatt caacctcgat
     5101 atatcagcaa agtggtggat ccccaaactg gagaagagcg aacaactcaa acagaagttc
     5161 tagggcaacc tttttcaaaa gaaacaacag aaaaagtccg tgaatatatg agagatgttg
     5221 tcgaaagcga aaactacggt agtgcttatg gtgtatatag tgtacctgga tacaatgtat
     5281 cggcaaaaac cggaacagcc caaatcgctt ctgatacagg gggatatcaa acaggagata
     5341 cagcctacct gtattcgatt gtggagatgg ttccttctga agatccagac tatgtcttgt
     5401 atctaacaat gaaacaccct aagacatatg atcgaatggc attggctaaa atcgcaaatc
     5461 cattgatgaa acgggcaatg gattttaaag aaactgaaga agattcagat acagaaacaa
     5521 aaacagaaaa agtatccgta gccgattatc gtaatcttga agcggacgtt gcagcagctg
     5581 atgctcaaaa aagtggactg caacctgtag tgatcggtaa tggtaaaaaa gtacaaaaac
     5641 aatctactgc caacggtgat cagttgatct ctggagaaaa actgatccta tatactggtg
     5701 gtgataagct gatgcctgac gtaacaggat ggtcaaaagc agatatcatg aagctgggga
     5761 aaatcctcgg tattgaagtt agttttgatg gagatggtta ttgtgtcaaa caagaacttg
     5821 ctccatatga aaaaatcact gaagacaaac ttagttttac tttagaagaa taagaagaga
     5881 aataggagag aaaagagcat ggaatggaca caagcattga ttcccattgt cagcagttgt
     5941 gcaatgacaa ttgccgcaat gccgctattt attggttatt ttcaaatgaa aaagcaaggt
     6001 caggcgattc gtgaggaggg accaaagtgg cacaatagca aagccggaac tcctacaatg
     6061 ggcggcttag tgtttctgat cggctctatt ttgacaggaa tttgggttgg agcttggcaa
     6121 aaacagctaa ctcctactct tttcatcttg ctttttgtat tagcgttata cggagtaatc
     6181 ggctttcttg atgattttat aaaaatattc aagaaaagaa acatgggact gaactcgaag
     6241 cagaaattga ttggacagat tctaggggga atcatctttt atcttgttta ccgttctgaa
     6301 ggttatccag gtgtattgaa tttcttcgga ctagatctac ctttaggaat catttatggt
     6361 attttcgctc tcttctggct tgttggattt tcaaatgcag taaatctgac agatggcatc
     6421 gatggattag ttgctggctt aggaagtatc tcttttgcag cttacggtct aattgcttgg
     6481 catcagcatc agtatgatgt attaatcatt tgcttaagtg ttttaggagg tttactgggt
     6541 ttcttcgtct acaacagaaa acctgccaag atttttatgg gagatgtcgg ttcattagcg
     6601 ttgggcggac ttttagcggc aatttctata atgctaaacc aagaatggac attgcttttg
     6661 attggtttga tctatgttat ggaaacagca agtgtgatgc ttcaagttac ttcctttaag
     6721 cttacaggaa aacgaatttt taaaatgtct ccaattcatc atcactttga aatgtgcgga
     6781 tggtcggagt ggaagattga tacagttttt tggttgatca gcattgtgac ttcgttgatc
     6841 acattatgga tcgtttggta ggagatgacg ggaaatgaaa aaaatatcaa catatgaaaa
     6901 taagaaagtg cttgtcttag gactcgcaaa aagcggagta agtgcggcca aattattaca
     6961 tgaattgggc gcacttgtca ccgttaatga tggaaaacct tttgacgaaa atccggaagc
     7021 acaagagctg ctttctttag ggataaaagt aataacaggt agtcatccaa tcgaattgtt
     7081 ggatgaagaa ttttcattga tggtcaaaaa tccagggatt ccctacagtc atcctttagt
     7141 agcaaaagcc caagaaatgg gtattccggt aattacggaa gttgagctag cttacgaagt
     7201 agcggaatgc ccaattattg ggattacagg aacgaacgga aaaacaacga caacaacgat
     7261 gacaggacta ctactgaatg caggagcaga tcaaggaatt gcacgtttag cgggtaatat
     7321 tgggtatcca gcaagtggtg tagcgcaaga agcaaaatca gaagataaaa ttgtgatgga
     7381 attgtctagc ttccaactca tgggaatcac agatttccgc cctcatatag cggtgattac
     7441 caatatctat gaagcacata ttgattatca tggtacaaga aaagaatatg tcaaagctaa
     7501 atggaacctt caaaaaaaca tgacagaaaa agattatctg atccttaact ggaatcagtc
     7561 agaactacaa gaattagcgc aaagaacaaa agcacgcgta ctgcctttct cgacaaaaga
     7621 agtgttggaa gacggtgtgt atgctgacga ttactcaata tactataaaa aagaaaaaat
     7681 aatggaaata tctgaacttg gcgtaccagg taagcataat gtagaaaatg cactagctgc
     7741 tatttctgta gcaaaattgt atggtatatc aaatgaagct atacgagaaa cgttgcattt
     7801 tttccatggc gtaccacatc gtacgcaata tgtaggagaa atccaaggca gaaaatttta
     7861 taatgattca aaagcaacca atattttagc gactaaaatg gctctaagtg gatttgaaac
     7921 gtctaaggtc gtgttattgg ctggcggatt agacagagga aatacatttg atgaattaat
     7981 tccttcatta aaaggaatca aagcaatggt cgtatttggc caaacaaaag aaaagttgat
     8041 ggatgctgga aaaaaagcag gcatcgagac aatagtaaca gccgattctg tagaacaagc
     8101 agttccttta gcattagaaa acagtacaga tggtgatgta gttttattat caccagcgaa
     8161 tgccagctgg gatcaatacc caaattttga aactagagga aacagattca tggaagctgt
     8221 gaaccgatta aaatagaaaa agtagaagcg agcgataaaa aatgaaaatt ttggttacag
     8281 gcggaggaac agggggacat atttatccag ctcttgcctt tgtcaattat gtaaagactc
     8341 aagaaccgaa tgctgaattc atgtatgtgg gagcaaaacg aggtctagaa aacaaaatcg
     8401 tccctgatac aggaatgcct ttccatacct tggagattca aggatttaaa cgaaaaattt
     8461 ccatgcataa catcaagacg gtccgattgt ttcttaagag tatccgtcaa gcaaaaaaaa
     8521 tcctcagtga ttttcaacca gatatcgtta tcggtactgg aggatatgtt tccggagcgg
     8581 tagtgtacgc tgcagccaaa atgggtattc caacagttat ccatgaacaa aacagtgtac
     8641 caggtgttac caataaattt ttaagccgat atgtggatcg gatcgctctt tcatttaaag
     8701 atgcggcttc cttttttcct gaaaacaaag cagttcttgt aggtaatcct cgagcacaag
     8761 aagtagcaga tactaaaaaa tcagatattt tgaaaacatt tgatttggat ccagaaaaga
     8821 aaacagtctt gatttttggc ggtagtcaag gagcacttaa aatcaatcaa gcagtatcag
     8881 tttttttaag tgaatatatt ccttcttctt accaagtttt gtatgcttca ggagatagat
     8941 attatgaaga gatcctaaat aaaataaatc ctgaaataca aaatattagt gtccagcctt
     9001 atatcaaaaa tatggcagag gtcatggctt ccagtgatct gctggtgggg cgtgctggtg
     9061 caacttcgat cgcagaattc acagctctgg ggttaccggc agtgttggtt cccagcccat
     9121 atgttacgaa tgatcatcag actaaaaatg caatgagtct tgttcacgca ggagcagcaa
     9181 aaatgattgc agataatgaa ctaacaggtg aatcactaag tcagacagtc aacgaaatca
     9241 tgggtgatga agaattgcaa aagcaaatgt gccgagcttc taaagaacaa ggaatccctg
     9301 atgcttcaaa acgtctttat gacttagtaa aacaaataat caaaaaataa aggcggtggt
     9361 cttagtgagt aagaaaaaag aaccaaaaaa attgtctcat ccgtcttctg atgaaaacaa
     9421 tttgactcct tggcaaaagg ctaaccgaaa atatctggca gaacaagaga tgaaaaacca
     9481 agagccaaaa aaagaagaca taacattaga tacacccctt tcagattctg aagaagaaaa
     9541 aacggttcaa gaggaacagc aagaagaaag ccagtccgag aaaaaaatcg aattttttga
     9601 agagatcaag caaaagaaaa acggtggacc atataacggt tcttttttga accggctgcc
     9661 caatttaaaa agtcaacggc acaaagtact atttcgtcgg ttagctttga tcatcactgt
     9721 attgggtata ccgctgattt ttttgatcta ttatgtttct ccttatagca aattacaagc
     9781 agttgcagta tcaggcaata agacagtcaa cagccaagaa atcatctctg atacaaaatt
     9841 gtcattagga gaaaatgttt ggggacagta ttttcatcga tctacttata tcgatcgcct
     9901 taaaaaagca cagccaagaa tcgaaacagc aaatatacat ttcaaaggga tgaatgaatt
     9961 cgatttggat gtaacagaat ataaagagat tgctttgatc gcaaaaaaca atcaatacta
    10021 cccagtgatt gaaaatggaa cagtattaga tgaaaaagta gcaaatccta caaaaaatct
    10081 ccctatcttg gaagagttca aagactctgc aaaaatcaaa gaattaacaa agcaatacaa
    10141 tcagttatca tcagaattac aaaaagcaat ttctgaaatc aagtacacgc caagagcaag
    10201 caataaaaat ctgatccaat tgaatatgaa tgacggcaat caagttattg taaatatcaa
    10261 taatcttgcg aaccaaatga aatattattc gcaagtagcc aaagatatgg atgaaaaagg
    10321 tgtgatcgac atggaagttg gtatcttctc gcatccttac ggtagcactc aagaaacgga
    10381 agaatcgggc caatcggaag aaacaactga aagtgaagaa aatgcggatc aaacaaacga
    10441 atcaagtgaa gaggcagaaa cgcaaaaagc acaaacacct ggatcgtcta gcacaaacgg
    10501 atcatctgat tcaaatgatt caagtgaaac aagtcaaata gaagataatc caagtacaac
    10561 tccgtcaagt ttaaatgaaa attgataaaa caactttaaa aagtaagaat gtactttcta
    10621 aaaaccagta atttatggta gaattggaag cagtgaatat atctattaat aagtatattt
    10681 taaaacggac gctagttgtt cgcttgtata tggaatagta agtaggaggg aatcccattc
    10741 atggcaaaaa caggaatgta tgtaggcctt gatattggaa cgacatctgt taaagttgtc
    10801 gtggctgaat atatcgacag ccaaatgaat attattggag taggaaacgc aaaatcagaa
    10861 gggattaacc gaggcattat cgttgatatc gataaaacgg tccaagcgat acaacgagca
    10921 gtacgacaag cagaagaaaa agcaggtatc cagatcaaag gcgtaagtgt cggtttgcca
    10981 gcaaacatgc ttgaagtaga aaattgccag ggaatgattg cagttaacgg agattcaaag
    11041 gaaatcaccg atgaagatgt cagaaatgtg gcttcagctg cccttgttcg ttcaatacct
    11101 cctgaacgtc aaatcgtgtc aatattgcca caagatttta ctgtcgatgg gttcgaggga
    11161 atcaaagatc ctcgtggaat gatcggcgta agattagaaa tgtacggtct gttgtttaca
    11221 ggacctaaaa cgatcatcca taacatacgt aaatgcgtgg aaaatgccgg attaatcgtc
    11281 aacgaaatgg tgattactcc tttagcgctg actgaatcaa ttctttctga cggagaaaaa
    11341 gattttggta cgatcgtcat tgatatgggt ggcggccaaa caacaacggc tgttatgcat
    11401 gataagcaat tgaagtttac caatcttgac caagaaggtg gcgaatttgt cactaaagat
    11461 atctctattg tattaaatac gtcatttaac aatgcagaag cgttgaaaat aaactacggg
    11521 gatgcatacc cagaacggac atcaccagat gaagaatttc cagtagatgt gattggtcag
    11581 tcagaaccag tgaaagtcga tgaacgctac ttgtcagaaa ttatttcagc tcgaatggaa
    11641 cagattttca acaaagcaaa agatgcattg gaccaaatcg aagcattaga gttgccaggt
    11701 ggcgtcgtat tgacaggcgg agctgctagt cttcctggtg ttgtggactt ggcacaagaa
    11761 atcttcggcg taaatgtaaa attgtatgtt ccaaatcaca tggggctgag aaacccggta
    11821 tttacaaatg taataagtat cgtggattat tcagcaaact tgagtgaagt gtatcaattg
    11881 gcaaaaattg ctgttacggg tgaaacctca gcagctcgtc aaatggtagt tgaacaagaa
    11941 acaacaaaca catatgagag ctatgaagca cctgaagaaa caatctacga tgagccggaa
    12001 ccaaaagagt ccggagaaaa tgtaaaaaat aaaatcaagg gtttctttac aaatattttt
    12061 gattaattca tcctgggagg aataagatat ggaattctca attgataata atatcaatga
    12121 cggcgcagta atcaaagtca tcggagtcgg tggtggcggt ggaaatgctg taaaccgaat
    12181 gattgaagaa aacgttaaag gtgttgaatt cattacagcc aacacagacg tgcaagcatt
    12241 aaaaaattca aaagctgaaa cagttatcca attaggcccc aaatatactc gtggtttagg
    12301 tgctggttct cagccagaag ttggacaaaa agcggcagaa gaaagtgaac aatccttacg
    12361 cgaagcttta gacggtgcag atatgatttt catcactgca ggaatgggtg gaggaaccgg
    12421 tacaggtgct gcaccaatcg ttgcaggtat cgcgaaagaa ttgggcgcat tgactgttgg
    12481 tgtcgtgaca cgtccattca cttttgaagg accgaaacgt ggccgttttg ctgcagaagg
    12541 tatcgctcgt ttgaaagaaa atgtggatac attattaatt atctcaaata accgtttatt
    12601 agaagttgta gataaaaaga caccgatgct tgaagctttc cgtgaagcag ataatgtttt
    12661 acgacaaggt gtacaaggta tctctgattt gatcacagcg ccaggttacg ttaaccttga
    12721 ctttgctgac gtgaaaacag tgatggaaaa ccaaggtaca gcattgatgg ggatcggtgt
    12781 ggctagtgga gaagatcgcg tagtagaagc aacgaaaaaa gcaatctcct ctccattgct
    12841 tgaaacatct attgatggag ctgaacaagt acttcttaac atcacaggcg gtttggatat
    12901 gacattgttc gaagcacaag atgcttcaga tatcgtagca aatgcagcaa ctggcgatgt
    12961 aaatatcatt ctaggtacat ctatcaatga agaaatgggc gatgaaatcc gtgtgacggt
    13021 catcgcaaca ggtatcgatg aatcaaaaaa ggaacgcaag tctagccgac cagctagaca
    13081 agcacaaatg caatcacctg ctcaaaagac tgtattagat atggatcaag ctaaaccaac
    13141 ttcttcagaa gaagaaaaca gttttggcga ttgggatatc agacgtgaac aaaatgttcg
    13201 tcctagagtt gatgattcca attttgacaa tatcgaaaaa aaagaatttg atacattcaa
    13261 ccgcgaagaa acaaaatctc atggcgatga tgaattaaat acgccaccgt ttttccgtcg
    13321 taaaaaataa aggagaggaa gagcacatga ttgctgacaa cttgcagaaa atcaagcaag
    13381 aaattcagga ttcgtgtgct cttgttcatc gtgatccgaa agaagttaca ttagtagctg
    13441 taacaaaatc tgttgaatcc gctcaagctg aagaattggt tagagctggc gttatgaatt
    13501 gtgcagaaaa ccgagtagat aaattattag aaaagaaaca agatttattt gattttcctg
    13561 aaataaagtg gcatttaatt ggtaatttac agcgcagaaa ggtaaaattg attgtaaatg
    13621 aaattgatta ctttcatgcg ttggacagtt taagattagc agaagaaatc cagaagcggt
    13681 tagagaaaga attatcctgt tttattgaag taaatgtttc tggtgaggaa tcaaaacatg
    13741 gaatttcacc agatgagctt ttaccgtttg tggaatcttt agctgcctgc acaaaaatca
    13801 aggttgttgg gttgatgact atggcgccta aagaagcttc tgatgagcaa atccataaag
    13861 tgtttggtac gctgaaagaa ttgcgtgatc ttgttcaagc aaaaggttat gcccatgcac
    13921 catgtagtga attaagtatg gggatgagtc aagactttca aattgcgatt gaagaaggtg
    13981 caacatttat ccgtgtagga acagcgctat tcaaagacga ataaaggagg aacaaaaatg
    14041 ccgcttttaa acagaggagc aattgctaat tttttcggat tagctgatga ggaagagtac
    14101 gaataccaag attatcctga aacaacaaaa aaggctgtac agccaactaa aaaaaataca
    14161 acacagaatc aatcaactca ttctgtatct gctgcgaata ctcatgaaaa acaaaaaacg
    14221 gcgacttcac gtcctgtaac gcatgaaagt attcagccgg ctgaaaagaa aaaagtaatt
    14281 gaactacatc aatcacctac aaaaactgta gcgaaagaaa gaacagcttc aagaacctct
    14341 acacaaccta aagcaaatct tgctggaaaa atcactgtaa tggaaccaag agcttattct
    14401 gaagctatgg cgattgctaa acgaatcatt gctggagaag caaccttagt gaattttcat
    14461 ttagtagaag aaaaacaagc gagaagaatc gttgattttc taacaggaac agtttatgca
    14521 ctagatggag atatcaaacg tgttggagat gagatttttc tttgtacacc gactgggatg
    14581 gagattgaca gttcaaccgc tcaatctttt gcagatgcga atttgtttga tctgtaagag
    14641 gaggaactac gatttatact attgcactat tacttcattt acttcaacgg gcagcctatt
    14701 tctatagcat tatcttgatg gtatatgcat tgctctcttg gtttccaggc gggtatcaat
    14761 cagggctagg acgattatta gctaagatct gcgaaccgta tatcagtttg ttcgatcgtc
    14821 tgcctttgag gattggaccc ttggatttca caattttagg ggcaatcctg atcttgaact
    14881 tagccgtaca aggtttagca cagatcgtta tatggataac tgtccattta gtttattgat
    14941 tgaagcaaca aaatctttat tctcagaata gataggaggg gaaaattttg gatgcaaatg
    15001 tataccagca ctttcgggca gatgaacgta catttatcga ttcggtaggc gattggattg
    15061 aacaggttca aggacaatat gcaccctatc tgaccgaatt tcttgaccca agacaatcct
    15121 atattttaga aacactgatt cgacaaagca gtgatttgcg tttcatgttt tatggcggat
    15181 atgaacaggc agaaagaaaa agatgtttga ttttccccga ttattacgaa cctgtagagg
    15241 aagattttga aacagcattg tatgaaatcc attatcctag caaatttgcc agcctaagtc
    15301 atgggaaaat ccttggaact ttagtgggaa cggggatcaa acgctcttac tttggcgata
    15361 tcatctcgga cggtgatcgc tggcaagtat ttattgcaaa tgaggtggat cattttgttg
    15421 ctgcacaagt aacaaagatt ggaaaggttg ctgtacgctt ggaaccaatc aaatacacag
    15481 aaatgattat gccgaaagat agctggacac aagaaagagg aacagttagt tccatgcgac
    15541 tagacagtgt gatctctgag atttataata tttccagaca gcggtccaag cagctgatcg
    15601 aagctggtaa agtaaaagtg aactggacag aaaatacaag acctgatttt gtacttgaac
    15661 tattagatat tatttcagtc agaggttatg gcagagtcca gatccaagaa cttgagggga
    15721 agacgaaaaa agaaaagtac agggtactgt tcggtgtatt acgtaaataa aataaaaagg
    15781 tggtttactc atggctttaa ctccattaga tatccaaaat aagacattcc cgacaaaaat
    15841 gcggggatat aatcaagacg aagtagatga tttcttagat ttagttgttc gtgactatga
    15901 ggaattgact caaagaaatc gagaattaga aaaagcagtc aaacattctg aagaaaaact
    15961 tgagtacttc aatgaattaa aagatgcttt gaaccaatca atcatcgtag ctcaagatac
    16021 ggctgataaa gtaaaaacaa gtgcaagcaa ggaatccgaa gtgatcgtta cttctgcaca
    16081 aaacaaagca gatgagttag ttgcgaacgc tgaaaaacgt gcacatcaat taacaactga
    16141 tgcagaagaa aaagcaagaa aaatcttgac agatgcaaca gaaaaagcaa gacagcttgc
    16201 gacagaaact gaagatctta agaaaaaaac acgagtattc catcaacgta tcagcttgat
    16261 gcttgagtct caattagaac aagtgaaaag tccggaatgg gatgaaattt tacaaccatt
    16321 ctccagctac gtgactgaca gccatgaagt gatcaaagaa gttttagcaa aacagcttga
    16381 caatgaaaat gatactgatg taaactcaga cataggagtc atagaagcac ctatgacggc
    16441 atttgataca caggctattg atatctcgat cgtgcctggt gaaaatgaaa acgagtagaa
    16501 cagaaaagca ctttgttatt cttaaagcga gccgatgaga gtggaagttc ggtaagacac
    16561 tgcatggtga aagatcctct acttgagacc tgcttttccg aaattagagt aagaagcagc
    16621 ggctgacctc gttattggtc acagagagtt tgcactagat agatgcaact aaatttgggt
    16681 ggtaccacgg catgttcgtc ccttgcggct gaacatgctt ttttgtgtcc ggaaaacaaa
    16741 taaaggagtg tatggttgaa tgaaaatgaa agaaaccttg caattaggaa aaacaaaatt
    16801 ccctatgcgt ggtaatttgc caaaccgaga aggcgagtgg caaaaagaat gggaagaaaa
    16861 tcgaatctac caaaaaagac aagagttgaa cgaaggaaaa cctagctttg ttcttcatga
    16921 tggacctcca tatgccaatg gtaatatcca tttaggacat tcattgaata aaatcagtaa
    16981 agacattatc attcgttcaa aatcaatgtc tggctatcgt gcaccatatg ttccaggatg
    17041 ggatacacat ggattgccga ttgaacaagt attggctaat aaaggcgtga aacgtaaaga
    17101 aatgtccatg gcagaatact tggaaaaatg tcgtgaatat gcactttccc aagtagataa
    17161 gcaacgagca gatttcaaac gcctaggagt tgcaggagat tgggaacatc cttatgttac
    17221 attagatcct tcttatgaag ctgcacaagt acgcgtattt ggtaaaatgg ctgaaaaaag
    17281 ctatatttac aaaggattga aaccaattta ctggtctccg tcaagtgagt cttctttagc
    17341 ggaagctgaa attgaatata aagatgtaaa atctccatct atttttgtag ctttcaatgt
    17401 caaagacggc aaagatattc ttgatgaaga tacagctttt gtcatttgga cgacaacacc
    17461 atggacattg ccagcaaacc aaggtattgc tgtaaatcca aaatttacgt atgtattggt
    17521 ggaagccgat ggccgtaagt ttgtcgtagc gaaagatttg ctagaaacag tccaatcaga
    17581 aatcggttgg gaaaatgtaa cagttctaaa agaatttgct ggacaagaaa tggaatatat
    17641 gactgcaagt catccattct atgaacgtga atcacttgtg attttaggcg atcatgttac
    17701 tttagacgct ggtactggat tagtccatac tgctccagga catggggaag atgactatat
    17761 cgctggtagc aaatataaac tatctgtagt gtcacctgta gactcaaaag gattgtttac
    17821 agaagaagca cctggatttg aaggtatctt ttatgacaaa gcaaatccta tgatcactga
    17881 tctattaaaa gaaaaaggag ctttgctgaa gctagatttc tttactcata gttatcctca
    17941 cgattggcgg acgaaaaagc ctgtgatcta tcgggcaact ccacaatggt ttgcatctat
    18001 cgataaattc cgtcagaata ttttggatga agtagaaaaa gtagagtggg ttatcccatg
    18061 gggtaaaaca cgtttgtata atatgatccg tgaccgcggc gattgggtaa tttcccgtca
    18121 gcgtgcatgg ggagtaccac ttccgatttt ctatgctgaa aatggagaag caatcatcac
    18181 accagaaaca atcgaacatg tggcaaaatt atttgctgaa catggatcaa ttatctggtt
    18241 tgaaaaagaa gcgaaagaac ttcttcctga aggatttacc cacccaggtt ctcctaatgg
    18301 cgaatttaca aaagaaaaag atatcatgga tgtctggttt gattctggtt cttctcatga
    18361 agctgtttta cgtcagcgac cagaattatc attcccagca gatatgtatt tagaaggatc
    18421 agaccaatat cgtggctggt tcaactcaag tatcacgact agtgtggcta tcaatggtgt
    18481 agcaccatac aaatcagtta tttctcaagg atttgcttta gatggtgaag gccgtaagat
    18541 gagtaaatct ttaggaaaca tcattgcacc agaaaaagtg atcaaacaat ttggtgcaga
    18601 tatccttcgc ttatgggtat ctagtgtaga ttatgaagca gatgttcgtg tttctatgga
    18661 tatcttaagt caagtggcag aagtatatcg taaaatcaga aatacgatgc gtttcttatt
    18721 agcgaataca gaagatttcg atcctaaaaa agatactgtt tcgtacaatg atttacgttc
    18781 tgtagacaaa tatatgaccg ttcgattgaa ccaagtaatc aaagaaatcc gagaagaagg
    18841 gtacgacaaa tataacttca tgcatattta ccgtacagtt atgaacttct tgacggttga
    18901 tctatcgtca ttctacctgg attttgctaa agatgtagtt tatattgaag cagaagatga
    18961 ttatcaacgt cgttgcatgc aaactgtttt ctatcaaaca gctgtagctt tgacaaaatt
    19021 attgactcct atcattccgc atacagcaga agaaatctgg tcattcctga aagaagaaga
    19081 ggagtacgtt cagttaagcg agtttcctgg ttatgaagag tttgcaaacc aagaagaatt
    19141 gatggatacc tggactgctt tcatggactt ccgtgataat gtcttaaaag cattggaaga
    19201 agcaagaaac agcaaattga ttggtaaatc tttggaagca aaactaactg tttatccaaa
    19261 acaacaagtt cgtgaaatgt taaaagcttt ggatgcagat attgcacaat tattgatcgt
    19321 ttcaccagac tactttgaag ttatggcagc agatgaacaa gtgccagata acgctatggt
    19381 atttgatgat gttgctatta cagtggaaaa agcagacggg gaaacttgcg atcgctgtcg
    19441 ccaagttcgt aaagatgtag gagtagatga aaaacttcct catctatgcg gtcgttgtgc
    19501 aaaaatcgtt gaagacttct atcctgaagc tgtagctgaa ggattcgaag aaaagtaaaa
    19561 gggaaaaggg ggtgtgacat gttctttgtc acaccccctt ttgttatcaa tcgtttaatt
    19621 ttccacgttc acgataccag ttatctggtt gccagatcca ttcgaatccg tctttttcaa
    19681 gtagttcgaa agctgcttta ggtcccattg atccagcttt gtagttggga aaatccggtt
    19741 gtgtttggtc ccaagctttt cgaatgacat ccacgatatg ccaagattga gcgacttctt
    19801 cccaatgaga gaagttcgtt ccatcaccat tcaacgcatc taatagtaat ttttcgtaag
    19861 cttctgggct attttcaacc atttctgcac tatttctaaa ttccaatttg attggttccg
    19921 tttcaaatcc ttgccctact tctttcccat tcaaggataa agaaaatcct tcagttggct
    19981 gaatatagat cgttagaaca ttaggtggaa gtgtcgtatc gtcacatggt tcatcgacag
    20041 atgttttgaa tacattaaca ggaacttgtt tgaatacgat gttgatccga gtcccttttt
    20101 cagtcaaacg tttgcctgta cgtacataga aaggaacacc tgaccaacgg aagttatcga
    20161 tagtgaattt gcctgcgacg aatgtttcag tctctgattg agcatccact ttgtcttctt
    20221 cgcgatagcc cttgaattgt acaccatcca attcaccttg agcatattgc ccgcgaacga
    20281 agttttctaa cacttcttct tcgttataaa tgcggatagc tttcaatgct ttgatctttt
    20341 ctgtacggat ttctttttcg gaaaatgcta ctggcggttc cattgcaagt aatgctacaa
    20401 cctgtaaaat atgattttgc accatgtctt taagtgcgcc actatgatcg tagtagcccc
    20461 cgcgatcttc tacaccgagg ttttcgccaa aagtaatttg gatattgtcg atatagcgat
    20521 tgttccattg agcctcaaaa atattattgg caaaacggat agctgagatg ttttggatca
    20581 tttcttttcc taaataatga tcaatcctga aaatatcttg ttctgggaat acttctctga
    20641 tttgctggtt caattcaaaa gcagactggt aatcagaacc gaacggtttt tctatgatca
    20701 aacgattgaa gccatttttt gtcataatat tttgtgattt caaatgagaa acgatcgttc
    20761 caaaaaattg aggtgccata gccaaataat agacacggtt accgtttaat tgatagtgtc
    20821 catctaatcg gtcagacaat tcttttaatg tctgataatg cgttgaatca tttacatcat
    20881 gggattgata gtaaaaatgg cttgcaaagg tagttgcttc ttcatctgaa ggattcaatg
    20941 cacggattgt ttctttgaca acttcacggt agtgctcatc gctccaggga cggcgagcgg
    21001 ttccgattac agcaaaatgc tcgcctaaat ttccttttct gtaaaggcgg aacaaagacg
    21061 ggtacaattt acgctgggct aggtcacctg taccgccgaa tatcgtaaac aatacatttt
    21121 tttcattaga catgtggata cactccttta tattttatcg acaaaaatcg tgctggccgc
    21181 cttaaagctg acggggattt tctttctatc attttggata gtgatcggtc cttcataagc
    21241 tgcgatgtca acgatctcat attcttcgtt gatattcagg tcaatagtga ctaagtaatc
    21301 caacaattct ttttcatcaa gcactcgtgc gatacgcact tttgtaccga caggatagga
    21361 ctccaatgtt tgtcggcgtt cttcatggac aacttcctct tttttaggaa tcgatcctcc
    21421 atgaggacaa tgttcaggat gattcaaata gttttctaaa tgatctgcaa gatgttccga
    21481 agtcacatgt tccaatactt cagcatcatc atggacttca ttccagctat agtctaaatg
    21541 ttcaactaaa aaaacttccc ataagcgatg tttgcgaatc agactgctag ctttttgcag
    21601 tccgcttgca gtcaattgta caccttgata aggggaatgt tctacaagct cttctttcac
    21661 aagtttagaa atcatttcac tgacagatgc agctgagaca tctagactag atacgatttg
    21721 tttattgttg actttcgttg tatctccacc tagttctaaa atgattttca aataatcttc
    21781 tcgatttggt gtcatattcg atcatccttt catggtaaaa aaccatcatt agtaagtgta
    21841 acaaaaaaaa cgttaattga ctatttttct aaataaaaaa caaaggattt ttagacgttt
    21901 ttacaacaaa aaacgaaaga tgatagagaa gactcattct ttcgtttata aaggatatat
    21961 atatacattg ggagggatct atttttcaga taacaactta tatgaagtgt ctgcagattc
    22021 gtcataaaga gtttgttcgg gataagaaaa gataagataa aaaccatact gatcacgtac
    22081 gactaaacga tattcatcta tttctaccac agatgtgcca agagactgac cgttgatcaa
    22141 aaacgtgtaa tcagatgtaa tctgtaattg ttgtttttgc tggctatcac taaagaacca
    22201 tgtaccttga tactttgaga gtccttctga cttttccgct tgttttttct ttttcaagta
    22261 aataaaactt gagagaacgg taatgagtga accaagaaaa tagatcattt tttttatcac
    22321 caaatcactc ctttatgaga aaataatcgc atagacatat tctttcttct ttatttcatt
    22381 gtaccgaata aaagctaaaa tttctctaag actttcgact ggttttttta ctgtttttct
    22441 acaaattatg ataggataca tagtaggaag aaaggtgaca taatttgaag tatcagcaag
    22501 tggaaatagc tttttttatt gaccgcccga atcggtttat agcacattgt atgaaaaaag
    22561 acggagaaat aattattgcg catgtcaaaa atacaggtag aggaaaagag gtcctgatac
    22621 caggcgctga agtggctatt gtatttgctc ctggacctaa acggaaaacc gcctatgatc
    22681 tgattgctgt aaaaaagaag ggtgactggt ttaatatcga tagtcaattg cctaatcggc
    22741 tggcaattga tggtatttta gacggcacga tccttttacc aggattaact ggtccattta
    22801 cggtatacaa gcgtgaagta acttatcttc actccaaatt tgatatttat ttagagacgg
    22861 tggtcggaca aaaagcattt gttgaagtca aaggtatgac acttgaaaat aaagcgattg
    22921 gtgcttttcc tgatgcgccc acactcagag gattgaaaca tataggagaa ttaacgtatg
    22981 ccgcacaaga tggttatgcc gcttatgtct tgtttattgc tcagttcgaa catcttcatc
    23041 tggcaacgat ccatgaagaa atgcaaccag cactagctga tatggttcga catgcgcagc
    23101 aaagcggagt tcaaatcctc gcctataatt gtcaagtatc ggcagatgag gtaactgtca
    23161 agcaggccat tccatttgat gtagatatcc cttttgaaga tcctatacaa tagaaagaag
    23221 gtaaaataat gatcaactta ggtattatcg gaacaaattg gattactcat caatttgtcc
    23281 aagcagcttt aagcacaaaa aaatatgaat tgacagcggt atattctaga catttggaaa
    23341 aagcacagga atttggttct cattatgaag gggatatcga attcgcaaca gatttgaaga
    23401 cttttttcaa tattactcat atggacacca tttatattgc ttctccgaat agtcttcact
    23461 ttagtcaagc taagcaagca attttggcag gaaaaaatgt gatagttgaa aagccagctt
    23521 tttcgacgcc aaaagaaatg gatgaaatca tccatttggc aaatgaacac aatgtgtatt
    23581 tttttgaagc agcaagaaat atccatgaat caggttttaa aaagattgcc gattacttac
    23641 cattaaaaga cgagataatc ggtgcaaatt tcagctatat gaaatattct tcgcgctatg
    23701 accaagtatt agatggagaa gaaccgaata tcttctcgac tcatttctca ggtggtgcat
    23761 tgatggattt aggtgtttac cttgtatatg cagctgttgc ttggtttgga atgccaaaag
    23821 aagtccatta tttcccaaga aagatttcta ctggtgtaga tggtcttgga tgggggatct
    23881 tacgttatga gaattttgat gtatcgatcc agccaggtaa aatcggtgat tcttatttac
    23941 cgtcagagat ttattttgac tcaggaacgc tagtgatgaa tggagtcaat gcaattgaac
    24001 aagcacaatt tcatgatcgc gcgcataaag aaatcattga tttggcggta acagctgcag
    24061 aaaatccaat ggcagatgaa gcagaggatt ttgccaatgt catggctcat ccgaaagatc
    24121 cagcttgggg attgttgtat gaagagtgga tcgagctagc tagaaatgtg aaccaagtga
    24181 tttatgattt aagaaaaaat ggcggcatca aattcgatgc agataatgag gaagattttt
    24241 aatgaacgaa tttgtacaag tatttcccga aaattggcag aaaaaatatg aggataaagg
    24301 gtttatctca ccttctctta ttcaacgagc agtttttcag ccactaagta ataaacaaag
    24361 tatagtagcg gtttctccta caggttcagg taaaacactg gcttatcttt ggcctctact
    24421 actaaacgtg gaaccaggtg aagcaagtgc gttggtcatt tttgcttctt ctcaagaact
    24481 agctattcaa gtagcagatg ttgcacgtga atggggaaaa gacaaagagt tgaaagtcca
    24541 atctttggtg ggcggagcca acgtcaaacg tcagattgag ggtttgaagg aaaaaccaga
    24601 aatcttgatt ggtacaccag gaagaatatt ggaattgatg aaagcaaaaa aaataaaagc
    24661 acatcaagtg aaaacaatgg tatttgatga agcagaccag ctatttgacg ctgggaacag
    24721 ccaaatcatt gatcaaattc ttcatcaagc tccaacagag tatcagctag cttttttttc
    24781 agcgacagca gatcgttccc ttgaaagcat tgaaaaaatc actgggaaaa cgtttgagac
    24841 aattgacgtg acagcagagg acgattctcg aaaaggactg agacattact ttttacgtgt
    24901 accgatacga aagaaagatg actacttgag acgtctcacg catatagaag attttcatgg
    24961 tctgattttc tttaatcaac tgactgaatt aggcgtaatg gaagaaaaat tgctgtatag
    25021 aggtgtaccg gtaggaagtc tggcctctga tcagaacaag ctactccgaa aagcagcgct
    25081 agaacaattc aaaaagaaaa tggtcagagc acttttgacc acagatgtgg cggctagagg
    25141 tttagatatt acaggtcttc cttatgtagt gaatgcagaa gttccgttaa gtgaagaagc
    25201 ttatttgcat cgttcgggaa gaactggtcg aatgggtaat gaaggaatag taattacact
    25261 cgtacaagat aataatctaa gagatttaaa acggctttta cgtccatcaa atataacact
    25321 tgaagagatt tttttatacg gaggtaagct gcaaactgag cagccaacca aagaagatgc
    25381 agctcctgca gtaaataaaa agtatgcgaa aactttttct ggaaaggagc agaacccaga
    25441 atataacaaa gaaaaaataa gaaaaaaagt taaaaataaa tcaaaaaaag agagaaataa
    25501 aggagcaagg cgcaaataag cgccttttta tgctatgatt atgaaaacgg gaacaaaatt
    25561 ggttgccaga ggaggggtta tgtgaaagaa cgtcaagaag agatcttgca gctattgaca
    25621 gaaaaccaac aaggattgac agcaagtgat gtagctgagc gcttaactat cgatcgaagc
    25681 aatgcaagcc gatatttaag tgaactatac aaggcccatc atattgtaaa aaccgctggc
    25741 cgaccagtcg tttactcttt gccaacggaa aagtcaaaat ctgatgaagt gcatgtcgac
    25801 tcttctacgc aagtgacttt tgaaacactc gttggagaaa atgattcttt aaaagtcagc
    25861 atacagcagg caaaagctgc gattctttat ccaccgcggg ggttgcatac gattattttt
    25921 ggagaaactg gtacagggaa gtcgatgttt gctgaatgta tgtatcattt tgcaatcgat
    25981 tcagagatgc tttctgcaga tgcgccattt gtttctttca attgtgcgga ttatgctcaa
    26041 aatccgcaac tgctctttgg acacatcttt gggatcaaaa aaggggctta cacaggagca
    26101 gctcaagata gtcccggtct aatagccaaa gcagacggcg gtatattgtt tttagatgag
    26161 atccaccgtt taccgccgga agggcaggaa atgctgttta ctttcattga taaaggtatt
    26221 taccgtccgc ttggagaaag tgcacaagta catgaagcat ctgttcagat cattggggcg
    26281 acgactgaat cttcagaaag tttcttatct acgttcaatc gacggattcc tatggcaatc
    26341 accttgccga atcttgcttc acgttcactg gatgagcgtt atgaaatcat ctctcttttt
    26401 atcaaacaag aagcgaatcg tttgaatcaa cgtatcgata tcgaaaaaga agcgattctt
    26461 gccttcatgc tttatgatgc ggaaggaaat atcggtcaag tgaaacgaga cttgaaacta
    26521 gtctgtgcaa aatctttttt acattaccgt actcatcatg agaaaaagct aatcattcga
    26581 aaagaagaac tttcccttca agtacaaaaa ggattactga aaatcaagga aataccggaa
    26641 cgtctcgacc gattcatgga cagcaaaagt cagtatttga catttgaacc aggatttgct
    26701 gatgttgtct ggtcacaaga tccagaacga aacatgcagg tctataacga tattgaggaa
    26761 aaagtcactt ctctttccga aaccggtgtg gagaacattg atctagagac cctcatttca
    26821 aaagatgtgg atgcttattt ccagacatat gtcaaagaat tgactaaaag ttcgattccc
    26881 aaagatcttt tgccagatga aatctggcgg ttaaccaatc aattgtatga tgtggctgaa
    26941 aaacggttag accgtattta taatgaaaaa gctcgttttg cttttgcttt gcatctgcaa
    27001 agtacattgg atcgtgtgag agaaggtcat atgatcgtcc acccagattt gaataacgta
    27061 cggaaaaatt ttaagaggga attccaggta gcaatcgatc tttcaacgat cattgaagaa
    27121 gaagaacaag ttgagattcc ttttgatgaa atcggcttta ttagtatgtt tctttctatc
    27181 aatctaggag aaagtgagcc tgttaaagaa aacaaagtag atgttctcat attgatgcac
    27241 ggcagacaga ctgcttcaag catgttggag atggcacaag aactattagg aacaaaagta
    27301 gggaaagctt ttaatatgcc actggttatg gaagttcaaa caatgtatga agaagtgtta
    27361 caatatgtca aaaactatca agagcatttg acgaatggcc tactcttgtt aacagatatg
    27421 ggatcattaa acaccttcag tgatttgatt tatgaagaga ctggcattcg gacgaaagct
    27481 atcacgatga caagtaccat gattgtgata gaagcgatac ggatggcaag tgttggaaga
    27541 agcttagaag atatttatca aaatatccag ctttcctttg aatcgatcgt acgtgatcag
    27601 ttcaaagcgg aaaagtctga aactttacag cgtaaaaaag ccgtaatcgt gacatgcttt
    27661 actggtgaag gagtagctgc caaattatat cagcgtatta tgccagtgat taatcaaaat
    27721 aaggtagaac tgatccagat gcagttttta gaacgtgaat cattcaaaaa acacatcgat
    27781 gccttattgg aagaatatga gatcaaagca attgcgggaa cagttgatgt tgattatcaa
    27841 aatatcccat ttttttcagc ctatgacgtt tttgatgatg aaaaactaaa tattttaaag
    27901 cgtatagctg atgatgagat cccgacagct aaaattgtcg attcacttgc tggatcatta
    27961 agcgatgtct tttctattga tgaactgatc cgttcattgc aaaagacagt tcagcagatc
    28021 cagaccgatt tgtcgattat cgtggaacct ggagtagata ctggaatcgt tatccattta
    28081 gccttcatgt tagacggatt gatcaaacaa gaaagccatc ggcaatttga gaaactgtct
    28141 attttctcaa aaatttatcg tttggaaatg gatatcgttc gggcaaactt gatggcacta
    28201 gaacgaaaat atcaggtaaa aattccagaa gatgatatcg catttcttac acaaatgttt
    28261 cttgaaaata aaataaaaaa atgaacacac taatcatact gtttacacac taaacatctg
    28321 tgtgcgcact ataaaaaaga gctaaaaagc atgaaaacgc tatttcagct ctttttttta
    28381 ttggcatgct tcttgcgtta tataaaagtg taaaaaaata aaaggagtgt taaaaatggc
    28441 aaaaaaaaca atcatgttag tttgttcagc agggatgagt acgagtttat tggtcacaaa
    28501 aatgcaaaaa gcagcagaag aaaaagggat ggaagccgat atttttgcgg tctctgcctc
    28561 agatgcagat aataatttag aatctaagaa tgtcgatgta ttattattag gtcctcaagt
    28621 acgtttcatg aaagctcaat ttgaacaaaa acttgcgcct aaaggtattc cattagatgt
    28681 catcaatatg caagactatg gcatgatgaa cggagaaaaa gttcttgcac aagcagaaaa
    28741 tctaatgaaa taaatcaagt atgcagttgg gggtataaca acgtggaaga tcaacaaaac
    28801 ctagaagcca tcatggggtt aatcatgttt ggcggtaatg caaagagcga tgcaatggaa
    28861 gcgattgcgg ctgctaaaat cggtgatttt gagttagcgg ataggaaaat cgctgatgca
    28921 gaagaatcac ttatacaagc gcatcatgca caaacagaca tgttgacaca agaagcacaa
    28981 ggaaatcata tgcaagtgac attattgact gttcacagtc aagatcactt aatgacatct
    29041 attgcgttta ctgatttagc aaaagaaatc atcgaacttt atcgtcgcgt atacagcgaa
    29101 taaatacaac ttcttttttg aacggaagaa gaaaaatttt tgaacggatt ttttattttg
    29161 ttataaggag aactctcttt atataaaaaa cttataggag gaagtaaaaa atgaacggac
    29221 tatcaagttg gatggagaaa tacatcctgc cggttgccgc aaaaatcgga gcgcaaaaac
    29281 atttagttgc tttgcgtgat gcttttatcg gcacactgcc cgcaacaatg gcgggatcag
    29341 tcgctgtaat gatcaatgca attattcgtg atttaccgca acagtttaac agtacctatg
    29401 ctgacagttt agcagcagac aaaggaatct ttgccgtatt gaatgtcatc atcggaatca
    29461 atggttttgt ctggaacggt acactagcaa tcgccggatt gatctttgcc ttttcttggg
    29521 ggtataatct tgcccgagct tatggagtaa atgatctagc tggggggatc gttggtttag
    29581 ctaccttgat tcaaggtatt tcctttggtc cagcattatc agcagcatta gatgtgaatg
    29641 ttccttcaaa tgtcgcagat gcaatcaata gttctgagat tggtgcaacg attgcagatg
    29701 gcacactgtc agttggatta tggggttggc taaaactaga tcatttgaat ggaaacgctt
    29761 attttacagt tatgatcatg ggagctattt cagtcattat tttttgtaaa ttgatgcttg
    29821 ccaacattac gatcaaaatg cctgattcag taccaccagc agtatctaaa gcatttgcag
    29881 ccattttacc agcgacgatc gctttatacg tcattgctat tatcaattat atcgtaggtc
    29941 gtgtagctga tgggcaactg atcattgatt tggtgcaaaa atatattgca gaaccattcc
    30001 taggattatc tcaagggttg ggagcagtat tgatcgtcac agtatttgtt caagtattct
    30061 ggttctttgg tattcatgga ccaaatgtat tggcaccagt gctagaggga atctggggac
    30121 aagcacaact aatcaatatt gatattttcc aaaaaggtta taacggaaaa actggtacac
    30181 cagccgtgtt agatgcaatc gaagatggaa aagcttatat gtgggtccgc ggatcgttcg
    30241 atgcttttgc atggtttggc ggatcaggcg gaacgatcgt cttactgata gctatcttga
    30301 ttttctctaa acgtgcagat tatctaacag tagctaaatt atccattggg cctggtatct
    30361 tcaatatcaa cgaaccagtg atgtttggtc tgccaatcgt attgaatgca atcatgttta
    30421 tcccattctt gattgctcca gtagtagcaa cagcaattgg atggacagct acttatcttg
    30481 gcctagtcgc tccggtatcg cagcaagtca catgggtagt accgccgttc ttattgtcat
    30541 tcttagcaac aggagcggat tggcgggcac cgatcgtaac attagtatgt atggtcgtga
    30601 ctttcttgat ttgggcacca tttgtcatct ctgcaaacaa aatggaccct gccgcaggcg
    30661 aacaacaata agatgaacgt gaggagcggg acgctttaag tttcgttcct cataatgaat
    30721 tttcgaggag gaactgaaat gattacaatt gccagtgcaa tgcaacaaga tgaaatcaaa
    30781 gaattgttag aaggatacaa tgaagaagga atgactttta catttaaaga aaaacaagga
    30841 atcaagctgt tctttgaaac aagtgcagaa gatccggaag ttgcggctaa aaaagcaaag
    30901 gaactaatca aagcacagcc ttggggaaca gtcctttatt ttcaatcaac agctgtttag
    30961 aaaatggttt aaaaagatag gatggttgag atgataaaaa acggtttatt tttatgtagt
    31021 attggttctt tgatcgtgtt gtatagtttg aatccacatt cgcaaaggta tgatttgtat
    31081 agtatggtca caggtctttt tctaacagga ttaggaatct atttcttcat gaaggggaaa
    31141 aaaagagaag aagcaaagga gaaaaataac taatggaaat cacgaaaaaa ttaaatattc
    31201 cagcatcgtt tttttacgat aaagttatgg actctgtcct tttcgatgta cgtaaagcga
    31261 ccggcaaatc agtaactaga aaacagctga aaaatttgga gtacgtcaaa caattctcgc
    31321 aaaataaccg ggctcgcata aaaatcgaag aagtcattga aaaccagtct tataagtttc
    31381 gtacatcgac aacgaagaat gaattcgtcg ttcattatca aatcaaacca ttggacgatt
    31441 cgacctgtga ggttcattac acagaaaaaa tggagtctta tggcatgctt caaaagttga
    31501 atgatatgct tttaggaaca atcttgatgt attttaaacg gagacgtttc aaaaaaatgc
    31561 tagatatgat cgaagcaacg tattaaatca atgaaacatg gtactattta gttattgaaa
    31621 aatgaagtaa gctagaagga atttttcata ggaagataga tctttcctgc gaatcctcac
    31681 tagctttttt gtaggaaggg gcagcaaaat gacaaacaaa gtaagagagc taggtgtatc
    31741 ttcgattgag gaaatgtttg atttagccac ttatgcattt aatggggcag atacacctga
    31801 aaggcgagaa cgttttcgta cacttgcgga gaattcttgg aattacggat tttttgatga
    31861 ggaggatcgg ctaacaagtc aagtcatggc gacccctttt ccagtgaatt tttacggaca
    31921 agagtaccta atggccggca ttggctatgt tgcttcttat ccagaagcaa ggggacaagg
    31981 cgggatcaat cagatcatgg aaaagatcct tgaagattgc cgtgatcgta aagtaagctt
    32041 atcttatctg gcgccattct cctatccctt ctatcggcgc tatggctatg aacaatcatt
    32101 tgataaaatc agttatcaac taaacagtcg tgatgtgccg tttatcaaaa aaaaatctgg
    32161 aaaaataaag cgtatggatt ttgaagatgc aaaagctgca atcagaagaa tttatgaaca
    32221 gatgccggaa aaccaacgag ctggtctgaa gcgcgaagac tggtggtata cgtataaatt
    32281 caagcaaaaa ggcaattacc agtttgcttt gcattttgat gataatgagg aagcaacggg
    32341 atatatcgtt tatcagcttg caacgtcttc ctttattatt gcggagtggg gatttttgga
    32401 tcatgatgct ttttgcagcc ttgttcgctt cgtaagttct cacaatggtg cttttgaaac
    32461 atttgaatat tcatgcggct acggcggtaa tgatcaaaat tatctattag aaaatccatt
    32521 tgcttctgta atgatcacac cttatatgat ggcgaggatc gtagatattt ctttgttttt
    32581 ggaaaattat ccatttaaaa agagacaagc tgcatttgcc ctacaaatag aagaagatca
    32641 ttatgcgaaa tggaatgaag gaatcgtgga agtaacaatc gaaaatggaa aaaatcatct
    32701 ctcaaaagta gaacaaacaa aactcccaat cgttcgagga agtatccaac atatcacgca
    32761 gctattatta gggtatcgta aagtggaaga gttggtattc caagaaagaa tacaggtgac
    32821 aaaagaatat gaagaaacgt taagctcaat cttgccacag caacagccaa ttcttaatga
    32881 ctatttttga taaaaaacgg gtgatgacaa tatttttgtc accacccttt tgtttttcat
    32941 ttggcatttg aaggaaaatg ttaaagtaaa tcctcttttt tcgtaaattt gaattttttg
    33001 ttttcttttg ttttagggtt ttcttttttg tggtcttgga ttgcttcttt cgtaatcttt
    33061 tcccgatttt ttttagatga atctaagcgt tctgcgtata ctttttcttt tggcttatca
    33121 ttcattggaa aggacctccc tacattattt cattctacct ctagtttatc atctgttaag
    33181 gactagtgga aacgttttgc ctaacttata agctgatttt tttagcagat aagcttgcaa
    33241 gtaaaaaaca aacaagctac aattgattta ttgaaattgt tcctgtagct cagtaggata
    33301 gagcaatcgc ctcctaagcg ataggtcgct ggttcaattc cagtcaggaa cgtataaata
    33361 acccctgtat cctttgcggt acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa
    33421 ctagttatca tttttatata aactatcgaa cacagtattg attttttctt tatcctgatc
    33481 ttcaagctct cgaacaatat gaagataagt agacattgta gtttctaaac tgctatgtcc
    33541 taaacgtttc gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgtgt
    33601 atgccttagt ccatgcaaag taaattgctt ttcaatccct aattctttta attttttgcg
    33661 caaatatttg ctgacggcgt ttgatgaaac taatccattt tttaagttga aaaaaacaaa
    33721 attatgaggg tttttgattt caaaattctc gaataattct ttttgattga ttttaaactt
    33781 ttttaagaga tcaatcgtat gtttatcaat ggaaattttc ctatttgaag tttcgttttt
    33841 tgtttttccc cattcattta atttataatt ccatgtttta ttaatagtga tgatttgatc
    33901 ttcgaaatcg atatcttccc atgttaatcc tagaagttca gcaaatcgca ttccagtggc
    33961 accagcaact aacacgagca taggagaaga gtactgcgca gaaaggtttt cttctacgag
    34021 tttcattaaa gatttaaatt gatcataatc taaatattta tcttcttttg gcttcaatga
    34081 atcttttcct ttgattactg cttttctagt tggatcaaac ggaattaatc cttcttctac
    34141 ggcatctttc aacgacgctc taatatggtt attaaactta ataacggtag attttacatg
    34201 gtctttagca tacttattta aaaagcgttg atatcccact ctatctaaat cagaaatcaa
    34261 taccgctggc atatatttct ttatgttcat taacgtatct tcgtattttc tataagtgat
    34321 aggagatact gttccttctt tataaagttg catccaatcc tcaaagtaat ctgataataa
    34381 tagatttttg cgatcccctt taaggccttt gttcaagtta tattctaatt cgttggcggc
    34441 atcttttgct tctccttttg tcttaaatcc tgattttctt atcttcgtgt attttccgtc
    34501 atcttttttg tatgaaattt cgtattgcca actatttcca cgtttgacta atcttgccat
    34561 aattgaatca gctctctttc tctgatacaa taggaactat aaagaagccc attgtttggg
    34621 ttttattatt ttttgcacat cctttttgct tgccggcgca aggatgtgct atttgtcgtt
    34681 ttaatggtat aattggatgt gtattagatc atccaatcag aggtgtttat tatgattaaa
    34741 gtgattttta aaagaataac tgaacttcca gagtttagat tatttgttga ttattggtat
    34801 gtctggtttt ttattgttgc attgctgata ggtctagatg tcatattaga aagaaaactt
    34861 aagtaagagt tgagttaata aattgaattc ctaaatgaga tattttgtag cccatatttt
    34921 gtttgccgac atcacctaat actatggagc taatcgtttt ttctaacaga ccaaaatcag
    34981 ataatctatt taagctacca tctattagct cttgtgaata gccagacatg ctgatatttc
    35041 cagtgaaatt ttcgtttcca cgactcatta agcatgctaa caattgaatc tcaatcgatg
    35101 ttaattgatt cagtacaaga agataatact cctcgttatc ccatgaagcg ttgttaattc
    35161 gaagtaaaca attcttataa agatttttat acatatctat tttattttgt gcctttgatt
    35221 tttctacctc gtcatttatc ccttcgaata ttccaatgag ttggtccttg ttctctaagt
    35281 tgaaaacatc ttctggaatt tgatcgcgaa tgttttctaa tgattcgttt aaatttttgt
    35341 agaatttctc gatgcgtttg aaacgcttct cgtttttaga cccaaaaata aagtgactgc
    35401 acaacgccac caatataagg aattgctcca ataccgcctt caactattaa ttcaagatat
    35461 tcttttttgg ttagtttttc attgctatta tccatagtta cctcctattt tgtcatttcc
    35521 tttacaagca ttgtgactcc tgatggcact cttttgtata ggttttatta ttgtgcacaa
    35581 tctaactctt agtggggcgt ggttcattta ttttttactt actttactat taatcatatc
    35641 ccattgagca taggattttt ctatgttcga tcctcttgaa ctaatttctc ctgtaaaagt
    35701 tactttatcg ccctttgtaa aggtatcagc attgtttaag tccttcgcaa aaattacata
    35761 tgaaacttta ggtgttgcag aaatatcatt ccaactttta tcatcgtact ctttgtctgc
    35821 tataatggct attctagtag tcattgattc gataacagtt ccttcaaaag tatatgtttt
    35881 accactaata tatttagtaa aagctgtatt ttgctcagta gctggagtaa tagaataata
    35941 actatctaag aaagcacccc agtcatgatt atttgtctct aaaaattctt caaattgagt
    36001 taggctttta ttgctgctgt tagatgtagt agtttgagta tcagatgatg agctttcctg
    36061 tttgttattg tcatttgcct cgtttgatga ggaaagcgag aaacctacgg tagtaaaaat
    36121 aatcccgata ataaggagaa tcataggtgt tttcttattt gtttttttga taaatcttac
    36181 aattaacatg attaaaccta taataaataa aacaatacca gtaaaaccaa atataccgtc
    36241 cattaataga tcctctttct cttttgatat tgaatattat aaaccaagca attctttttt
    36301 cttaaaatcg aattcttctt gattaataat cccttcatct aacaactctt tatacttttt
    36361 aatttcatct gcacttgaaa tttgtgtttc tttggaatta ttatctaata tagattgttg
    36421 cttctctata tattttttta aattttccat ttcattccaa tatttttttg taaacataac
    36481 ggtgttttca tctttcgtgg ccgctaatat acctccgcga ctttcgtttc cgcctagcaa
    36541 ggtaaattgt atataaccat tactcatacc tggttttttt aattgtacgg ctgatatatt
    36601 tttaaagggg atagtttttt ctcctttaat accttgatta actaaattta taaatccttt
    36661 tctaataatt gaaatagaat catcagttac tttaatcaag gtttttcctg gagattttat
    36721 taaaatctct ttttccattt tttcttcctc atttctgtga tatgattttt tttgtagaag
    36781 ctcatatatg aggaaagagc ccgtgttgca gcacgggctt ttttaatgtt ttgctgaaat
    36841 cggttttttt aataattctt gatgtattca tacatattgc cttgcgtaag aatatttttt
    36901 cttaaaatag cattggcaga cagcataaca agtgtatctg agcttattct gaatagaata
    36961 atactccata aatttttcga gattaaactg agatttatca gtcagttcgt tctcaatata
    37021 gatatttaat aaaattagaa tagctatttt atctgcttct gtttcaaatt ttgagtgaaa
    37081 agttgtagaa gtatcgtaca aaactgaaaa ttcaaaatga gaggcgctga aatgtgcaag
    37141 ttcatgagat aaatgaaagg cttctgcagt ttcaccgtat agattttcat tcaaaaaaat
    37201 gattctgggt tttggatagt agaaaccagg ctctttcatc tccatataaa ctactttcaa
    37261 attgtattcg ctcaacattt ctttcaattt caaatacata caaaccatca ctccaactat
    37321 tcattttcct ctaaagcttt agcaattgca atcgctttac gcattgtctc cttagatatt
    37381 tcttttccat caaaagaaaa aacagtatcg tcttctgata aatccacatg tttaggggtt
    37441 tctctttctt ctctacctag aaggtagtct acagagacat cgaaatagtc agcaatccga
    37501 cttaattcat ctgaattagg agtattattt ttccactttg ctagataacc gttagaatat
    37561 ccaaaattaa tttctaactg ccgtatagat atctttttcc tcttcgccaa gtcttttatt
    37621 atttcatagg tattcatcga taaaacaacc tttctaaatg tttacaaaaa aagtttagaa
    37681 aaatacgcag aaataatttg actaattctg agtaatgagc tatactatat cttgtaaaca
    37741 gatttaacaa ctaaaaagac aacaaaaaac actattgata tgtaaatgca gaccgccaag
    37801 aaagctttaa aatcaatgtt tttatgtctt atttaattat gctcttagta tagagtatta
    37861 ctcagatact gtcaattgaa tttagaaaaa agttgttaaa tttgtttacg aatataaaag
    37921 aaaggaatga gaaatatgaa cacaccgcaa atttttaatt tcgaacaaaa cgaagttcgg
    37981 acaattttag taaatgatga accatatttt gtaggcaaag acgttgcgag tgttttgggt
    38041 tattcaaaca ctaaagatgc tttgtcgcgg catgtagatt tggaagataa gatggggtcg
    38101 cgaatcacga cctcaggtca atcaagagag atgacaatca tcaacgaatc tggtttgtac
    38161 agtttaatct taaaatcaaa acttccctct gccaaaaaat ttaaacgttg ggtaacaagt
    38221 gaagtgttgc cagcaattag aaaacatgga ggttatctaa ctccagaaaa agtagaagaa
    38281 gctttgctta atccagatac aatcattcaa ttagcaactc aactaaaaga agaaagaact
    38341 ggaagattaa tcgcagaaca aaagattgca gagtacgaac ctaaaatctc ctatttagat
    38401 agcatattat cttctacaga ttcagtaaca attagtcaga ttgcagcaga ttatgggatg
    38461 tctccacaac agatgaataa attacttcat aaactaggta ttcagaaaaa agtcggtaac
    38521 caatggttat tgtgcaaaaa acacatgaac caaggataca caaaatctca tacaactgag
    38581 atcccgaaag ccgatggtgg cactaaaatt gtaatgaata ccaaatggac acagaaaggg
    38641 cgtctattta tctacgaatt actaaaaaaa gaaggatatt accctcaaat ggatttagag
    38701 gaaattggtt agaaaggagt tttagtatga ctgacattgc agaaatcact caacgagata
    38761 gagaaaaaat caaagaatat gtcgaaagtt caaagttctt aacttacacc atgcttgctg
    38821 aaagatttgg aattagcaaa agctacttat ctttaatttt aaacggtaaa aagacttctg
    38881 cagaagcaaa cagaattata gattcgatta tcactatgta cgaattgtaa agggaggaac
    38941 agctaatgca atatctagaa gcaaaaatcc caattccaga aggctatgta attatctccc
    39001 aagtggatta tgaggagtta aaaaaagctg atgatactgg tagatggatg acgttgccag
    39061 aagtgctaga acggattaac agaaaatatg attggtttac ttctagagtt ttaaagaacc
    39121 caagatatag aaatattatc gatatcgaga aaaacaaaaa tggatttgtc tattatccag
    39181 ttgaaggaag agacacatat ctatttttaa gaagtaaaac acttgaattt ttagaaacaa
    39241 atttttcgga aatcttaagg aggcaagcgg atgggaaaat ttaatagagc gctagtgttc
    39301 agcgcaccgc taatcatcta cgctttagga ctttggggaa gcaggcaagc gttgatagga
    39361 acgattgttt acatggtttg gatttttatg gggcttgatg aagctgaagc tgagtacaga
    39421 gcgaaaaagc caaccgaggg ggctgactaa aaatgaatag aaaagagaaa ctagaatgta
    39481 tattactatt actcagttta attctttcac taatttctct attgggaagt ttgtattttt
    39541 gatatcaaca attttgtgga tttgggttct atttagagta aatatcattt ttgtttggtg
    39601 attaaggagt ttattaaaat taattttccc tacttcaaat gcaaggtaac aagatatagc
    39661 acttttagga ggaatattta gcggtacagc ttcagagtat attctattat catcgactga
    39721 tcctccttta gcaattaatt tcttaaatgg agtagctgac catctgcggt ttaagttagc
    39781 ggatgaaagt tctaaattaa ctaacatagc tggttctgtt gaatagttag aaatgattac
    39841 ttttgtataa atcatatctg cagcgaagta agaagcatta agttcaactt ctagttgagg
    39901 gcgcattcct tttattttta tccctgttaa aaacgtactc aatataaaac ttattattga
    39961 catccattga aaaattgtta agtgaaaaaa attcaaaata aacaccacca gtttttaact
    40021 aaattatacc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg aaaaataaag
    40081 aagctgtgac tacgagctta caagtggcag aaagcttcga gaaaaaacat caacatgttt
    40141 taagagatat tgatgcacta aaaaaagatg tgtccaattt tggacagatg tttgtagaag
    40201 gtaatgaacc agattcatat ggcagaaatc gacgagtttt cttcattagt agagatggat
    40261 ttttcttgct ggctatgggg tttacaggaa agaaagctat ctacttcaaa caaaaataca
    40321 ttgaagcatt caacgaaatg gaagatgtta ttcgcaagaa tactgttcct caaacaattg
    40381 aagatatgat gatctatcaa ttagaagaaa tgaaagatgt taaaaaagat gtttccatgc
    40441 ttaaagatac tatgcgaatt agcggacaac aagagtttga aattaagcaa aaaggaaata
    40501 tgaaagttat gggagttcta gggggaaaag aaagccgagc ttatgaagaa atcagcaaaa
    40561 aagtattctc aaaattttgg tctgaattta aacgtacctt ttcaatccca agatatggcg
    40621 agttacctcg taagagattc gatgatgctg tttcatttat tgaaatgtgg ttgccagaaa
    40681 ctgcgatccg tatggaaatt gatcaactga acagacaaca gagacttttt ggtgatgaca
    40741 atgaatagag ctgaagcgct aagaataggg acggcaattg ctaattgctg gtggaaatac
    40801 tataaaccaa tcatcctaag ccaacaacat attgacaagc aaaaagcatg gcaacaaata
    40861 aaaaagtgac tccgccggca agcaaagagt cacaaagaaa acacatcata aggagatttt
    40921 agcatatgga aaaagaactt tccactctag atcaatattt gattgatcct gattggggca
    40981 agccgaaaat tgaggaaaca agtggtcgaa aaatcagacg aaatcttttg acgaatgaag
    41041 aactagcttg ggatcaagat gatttaggca accatgtaac tatttgggat catgtttatc
    41101 ttatccatct atcgaagcat tcgaataaac ctgaatatat ttacgtcatc gaagatggct
    41161 tgattgatgc gctagaagag tacgacagag ataacttgat tgatatctct tattacggac
    41221 caggtaagaa atacattgct gaaatggagg cagaatttga tgagtgaaat caaagggaca
    41281 acgaactttg aaaaactttt tagtcgtaag ttaaataaaa ttctcaagaa aaaaggaaat
    41341 tttgattatt tatcttgggc tcacgcgtgg gagattatga aaaagaatga tccacaggca
    41401 acggtaacta ttaatgagta caaacactac agggttgttt ctggaactca tcaagacttt
    41461 cttgttgagg aatataaacc ttttcttatg gatgaaactg ggacttatgt atctgtctca
    41521 gtaacggtta aaggacacac ggaaaccgaa ttatttcctg ttttagatta tcgaaaccaa
    41581 ccagttgtta aaccaaatgc aatgcaaatc aataactcat tgaagcgatg ctttgtgaaa
    41641 gcattggctc tacacggact gggattatat gtatttcaag gggaagatat tccaacacca
    41701 cctagaatcg atacaaagaa attaaacatg ctagagacga ttctagaagc tttcaatgag
    41761 cagatgggta aagatatgac caaaacctta atcgaatatg ttaatgagca gacagataaa
    41821 ttagggctct tagctgataa cgttgaaact attgaacagt taagctatga gcaatgtgcc
    41881 ttgatggagc gagcaatagc agctaagaga aaagaattag ataagaagtg atatgagtgt
    41941 ttaaaccatt aatcgattca tattcagcgg ttctgaaaaa gttcaaagga aaagacataa
    42001 gcgcaaccat caatgaggaa gtgaacattg atcgactaaa gacgatgtat gacggctacg
    42061 atggtgatcg agtcattgaa attcgtttta ttgatcctag acgtttcacc gtacagcaac
    42121 gaaacttcat ctatgcgctg ataggcgata tttttatcga tacaggcatg ccaacggact
    42181 tctggaagga attcttctac tttcgttttg aaggtgtcac agggcgcaaa ataagcctga
    42241 aagacgaatc gaatacaact gtgagtgatg ccaatgtctt agcaaatatc atcttagatt
    42301 tcatctttga acatcatatt cctttcaaag aaggctatga gattttacct gcgaatcaag
    42361 aatattactt ctacaaatgc atcacaaaaa gagtctgctg catctgtggc aaaacaggag
    42421 ctgacatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa gttgatcatg
    42481 cagagtacac atttgcagca ctctgcagaa tccatcacac agagaagcac aaaataggtg
    42541 tgattaattt caaaaataaa tatcaaatca aagggatcaa attaaaccag aaaacaatca
    42601 aaaagttaaa tattggaggg taaaaatgac agaacatcga agttattatg cgattatacc
    42661 agccaacgta aggtacgaca aaagacttaa accaaatact aagttgttat acggagagat
    42721 aacggccttg tgtaatgaaa gaggcttttg ttgggcaggc aatgagtact ttgcagattt
    42781 atatggtgtg aataaagaga ccatatcgcg atgggtaagt gatttgatta agtttggata
    42841 cttgaatcgg gaaatcattt acaaagaggg taccaatcaa ataatcaata ggtacctacg
    42901 aattaatcaa taccctattg acgaaaaacg caatacccct attgacgaaa aagtcaaaga
    42961 taataataca tctattaata atacatttaa taatacaaaa gaatatataa gagagttacc
    43021 gccttcgaaa aaatcgaagg ctaagcccgt ccgtcataaa tacggagagt ataaaaatgt
    43081 tcttttgtca gatgagcaga tggagaaact caaaacagaa ttccctaatg attaccaaga
    43141 gcgaatcgaa cgactgtcag agtattgtga atcatctggt aagacttata aaaactattt
    43201 ggcaactatt cgaagttggg caaggaaaga aaaaagtgaa cctaagaacg caagcagtgg
    43261 atacaagcgc acaggaagac gagagaagct tcctgaatgg gcaatcgacc aagaagccta
    43321 tctcaagaaa aaagcgctag aacgagctaa tagacaatca aaagcaccat tctaagaggt
    43381 ggaaaaatga agatcgatta tctagaacta attaatgaaa tagcgaatta taaaaagggc
    43441 gaggaattag acgtcctgag agacgtatat gatcaactcg aagaagctgg aattgaagga
    43501 attaagaatg atcgttcgag ttggagtaag ctcagatact atttcgcact ttatatcgat
    43561 acaacacaat taagaaattt agcatatacc aaattactat ttgttgattg tgttaaaggc
    43621 ttgcaaaaac atcttaatga acttgagcag gtgtaatcag atggacctaa agacatttac
    43681 agcacagatt gaactaatgc atcaagaagc tttaagacaa agtgtatcgt acgaagacaa
    43741 gtggctcaac acgttccatg gcggacgtga gagcgcactt gatcaagtac tcaaattact
    43801 gaaaggagaa tgtcgggatg gataagaaag cggcaatgca gcgaattatc gaattgactt
    43861 attcagaaga ttggcaaaat gacaaagaag ctgcttcaga agtgatgagg cttggaagag
    43921 cgatgtgggc agacaagagc aacaagccaa gaccacgaaa aatcgcaatt tggcacggtg
    43981 acaaacttct agtgataggg acagctgaac agttagcaag tctcacaggc ttgcacgaga
    44041 aaatcgtgag gaaaagagca aggtgtggct acacagacgc taagaagaga acgtttagat
    44101 acgtggagga atcatcatga caacagaaga agtgattcaa atgcgtattc gaagccttca
    44161 gcgtgagatt gacgatctgg aacgaacaaa ggcagtgatg gtcaatgaaa cggcgagaaa
    44221 ggcaatcgat ttgcacatag agaatttaag aagggaaatc catcgattgg aggaatgagc
    44281 gtggataaga aagcagcaat gaaaagaatt gctgaattaa ccaagtcaga atcttggcaa
    44341 gaagacaaag aaatagttgc agaagtccaa aagctcggta aatcaatgtg gactgaaaag
    44401 cccaaacgga gaacgccgag aaaaattgca atctggcatg atgaccgaat tttagtaaca
    44461 ggtactgctg aacagttatc tgaaattact ggattaagca aaaacattat ctgggataga
    44521 gctaggagct tatggattga ttcaaaagga cgacagttta ggtatgtgga ggagagataa
    44581 tggatctcat tacacaatac agtgacatca tcctcaagaa aatcatgatg aagattcaga
    44641 aagataaaaa atcaaaagaa cgagctgaat tagttaagtt agaaatggct gaaacaggag
    44701 caggagtgcg aagtagcagg cattggaaag cagcagcaaa cattgaattt tattacaacg
    44761 aaattcaaaa agggttcgat cagatgcgtg agctggatcg gcaaacaaat tggagcaaga
    44821 aacttcatca agatcgtttc aaatttgtag agaagtataa agaaatatta gaagagtatt
    44881 tgaggaggac agcaaatgat aaaaaaactc gttcaattca gcatggattt atatgatatc
    44941 gaatcaggag caacactatc tgtggaatcg gaccatctaa tcataaattt tggtggaaag
    45001 cgccagatta ttttgtgggt agttgatgat gtactgtttc cagaaattgt tcatgatttc
    45061 gaagaatcaa aagcggttga gtttgaaata gtgaaaaaag taatggaatt gattgaaaaa
    45121 tacgaggagg acagcgaatg ataccgaagt ttagagcgtg ggataaacga aagaacgtaa
    45181 tgagagatgt agccgtcttg cattttacta aaaacggcaa aacaaacttt attgaatatt
    45241 ggataaatcc taccgaattg aaatcatatc acgtgcgaaa catcgacctc atgcaatcca
    45301 caggaatgaa agataagaat ggtgtggata tatttgaagg ggatatagta ttagtcagcg
    45361 tgcgaaatgg cttcgattac ttagataata aagtctgtat tgtcaaaaat tcaatagatt
    45421 attccggatt agtttgtgcc actgttgatg aagacttaga gtatcaaatt tttaacacag
    45481 agctgtttga agaatacacg tacgaagtca ccggaaatat atacgagaat agcgagttat
    45541 tggaggaaca gcgatgaata aacaggaagc aatcaaaaag ttagaaagta ttaaagcgat
    45601 aggaaatgat gcaatagctg cttgctataa cgagagtata aattcaggta ttacgttaat
    45661 gaaaaaaata gacgaaccgc agaaaccagt tattccacaa ctcgtggccg gttggcttga
    45721 gaaatctacg gaccctttta caaaagctga aaaaatagcg tatttaatca aatctaaaga
    45781 tggtgattca tattatttct gtgattggtt tgtacgagat ggcatagtga cgcaagagca
    45841 aggagaagaa ttactcgctt gggcaacaag acaatcatat gaaacactat tgagcctata
    45901 caacggctac gaggttgaga aagagccgtt atgggcaata aagaatgccg atggaaacta
    45961 tcttactaaa tgtgctttat ggggaaaaga tggagtaaat tatagttttg aatgcaatcc
    46021 atctcatcga ttgcttttca ctgataaagc aacagcggat gctgcagcat tgttggtgaa
    46081 tggaacagtg gaagaggtgg tagaaagatg aaactaaaag acggatttta cgctagcagt
    46141 cacggtatcg gcggtttaat gctagatatg ccgacaaaga accctaaaac acgcaagaaa
    46201 tcaaaattca aagtcggtga catggtccgc tgtgaagcag aagagttcgt ttatccgttc
    46261 agaggatacg ttaaaaagat actgtcaaac tcagcaatca ttcgtattga aaatacaatg
    46321 aagtgtgatc gttcgactgc aaaacacaag cattatttag ctgtagcgag attagttgac
    46381 atggaagtaa tcaagagcaa ataaaaaaag ccggatcgct ccgactgatt caataaatcc
    46441 aacacattta ttatatcaca taaaggagcg gtttgacttg atgcaattgt tacgagaggt
    46501 agatttcaaa cagacaagat gtaatgcgag agatgtgctg aagaactttc ggcgtttgga
    46561 gcggatggca ggtcgctctt tgatagatat taagtcgccg attataacgg atatgccgaa
    46621 ggcaccgaag catggcaata aggcagaaga cgcgattatt cagatgatgg atatagaaac
    46681 ggagagagat gcgattctag cggctttgat ggctcttagt ctgattagtc gtcagatact
    46741 ctactacagc ttctgtgtgc cagatagctt ctcaaactac agaattagcc gtgaagtggg
    46801 ttattcagaa agaagtatac aacggatgaa gtcggaagct ctaatagagt ttgcagaagc
    46861 atataaacac ggaaaaataa ttgcttataa ataatttggc ggttttttgg cggaatgatg
    46921 gcggttttta gacatttacc agtgttatta tggtagtgtc gaaagattag gaaacaggat
    46981 cgacaaaata aacgaaggga ggcaatctcc ctcatcgttt taaacttctt cttagataga
    47041 cagcaactaa ttatgaagaa aaggatgtga attcaactcc tcctaaattc ttcatcggtt
    47101 gctgtttatt ttgattagac agcagcactc acaaaactaa acatgttctt gtcgtctttc
    47161 aactgctgct gtctattaat ttatgtattg gagggaagaa aaatgaaatt atcagtagaa
    47221 ggcactccag aagaaataca agaattgctc caagctattg gtagtagcaa ggagcaaaag
    47281 gtaagtgttt ctaattcaga tattgacggt atttgcaatt gtttaaacag agaaaaaata
    47341 tctaatcctt actaagagaa aatatgttcg ttaatgaatt tccaattttc ctctgtagct
    47401 ctaccttgat aatttttttg cagttcacag atgaataagg aatcgttatt atcaagtact
    47461 gtatttaatt tttcacacat ttgatttgga ttcaaattag ttttaactaa ccaaaaagat
    47521 ttttgtagct ttatatatgc cccaaattct tttattattt caaatacttt atcatacttt
    47581 tgccctgggt tattaagatc ataactaatc atgtagggtt tatacatgtt gtcttgcaca
    47641 tccttgtttt atatttcagc ggaccactcg ctgataaata aaattatacg cttagtattt
    47701 attttcacaa tattaattta tcgtaataac ttttgagtaa atagaacaaa aaacctgcac
    47761 tagtttccgc tagtacaggc agtgactata tcggttgata atctagcata tattaaaaat
    47821 aattgcaaga aaagaaattt atagtggttt ataccaaatt atcaaagcaa tgttattttg
    47881 ttgctgtcta ttgtttttta attattcaca cgataactaa aggtgggtga agagaaatga
    47941 ttccattaat aatttcaatt tttgcgctct gtcttaatgt ctatatgatt ggatttaaaa
    48001 atgggcaaaa taaaaaatag tagcagccaa gaataatttt atagtgtcac tgtggcggaa
    48061 agggtagacg ctaagcatgt gtgctaggtc aatgcttcgg caaccatgca aggttcgatt
    48121 ccttgccagc gacattaaat gcctatgacg gttacgacta ccgaaaaaag atcgttaaga
    48181 agctatacgg tgctacgtac ggcaatgtag taagtgtgct atctgtacac caccaagctt
    48241 cggtcactgt ggcggaagta gaagacgcag cggtaaatgg cgagtagcct cgtgagagcc
    48301 tggtaagttc tcgtgagtgg tgcaatccca ctccagcgac tttaagcaac cgaggcatcg
    48361 gcggtttaaa aatatagggg tgcgcaattt cgtacgcgtt ttgtgcatcg tgcaagttac
    48421 tattacatat tagatcactc tttgagtggt ctttttattt ttgcacaaag gaggaaacaa
    48481 caatgtatag accacaatac ttagaacaga agtatgaagt aatcactgtt cataaaggta
    48541 atggcgaaaa agtatatgag tatagaagac caataaagag cgatacatat aaacgaaagg
    48601 aaaacaatga agttattcca ttgtatggca aaagaatagc taagcattaa ataagattgc
    48661 gaaaggagac ggaacatgac cgaggaattc tatagatggc tattacagtt gacaagagaa
    48721 gatcgtttgg ttaagttcta tcagtctcct aaatggcgca ggcttagaga gaaagcgatg
    48781 aaacgagatc actatgaatg ccaagagtgt agaagactag gtaagtatca tagagtagag
    48841 aacgttcatc atataaagga agtcaaggat agacctgact tagctttaga tttagataat
    48901 cttatttgtt tatgtgttga acatcataat gaagttcatg gcagatatct tacagcatta
    48961 gataaacaag agaagaagat agaaagcttt gctaacttcg atgcaagtga aaggtggtaa
    49021 gtgcatgatc atcaatgata atggcagaga gtatgataca gaaaagattg aagagtattc
    49081 atcttatact cagggattaa ttaaacgttt gatatacgtt cgctatgtag gtattaggga
    49141 tctgttatca gataactgtt gtagtaaata caaagtgaat caagtaagag aagcgttgaa
    49201 taaagataat aacgtcgaaa gaataaaaaa tgtttttgga tatagtattg aagagattaa
    49261 ttattacatt gacttcgctg aagctttcat tccgatggtg agataacccc cccttaaaat
    49321 aaatcgcaaa ttttttgggg gtgatgaaac ggagggggct gtcaggaaaa gagatttttt
    49381 cgaactttat catgaaagga gggctaaaat gtttaaaaac gaattgtctc aaaatcgcta
    49441 cagagaaaaa ttacgccgct ctttaataag ccaattggaa agtcagaaaa caaatattga
    49501 gccattctta gataatgttg atcgttatat cagtttatgg gaaacggcga tatcactgga
    49561 agaagatata tccgagaacg gcattagact ggagaatggt aaaaagaatg aatcagtagc
    49621 gttgcttgtt tctgtcaaca aacaaatggg attgatgttg gataaacttg ccattactcc
    49681 tgaattggta ggtgaagcaa atgaatcaat tcctgagtta taagcatatt gaaaattggt
    49741 tcaaagctat agaagaaggc actatcaagg tatgcaaaga gcaattattg ctaaaaaatt
    49801 atctagaaga aagagtcttt actagagaag atatttactt cgataagcag atggtagagg
    49861 attcaatcaa tataccagca caatactttc cattcgaatt aattccgtgg gaaaaatttc
    49921 tacaatgttt tatttatggt gttcgatgga aaaaagataa aacactagtg ttcaatagat
    49981 atctttcatt aatgggacgt ggtaatggta aaactggttt tgcttcttgg aacaacttct
    50041 ttctactaac cgctaaacac ggtattaaaa attatgatat tgatatctat gccaataatg
    50101 aaagccaagc aaagactagt tttgatgatg tatttaaagt aattaaagat catcctgatt
    50161 tagataaaaa agtatttaaa gctacgaagg aagttattca aaatatcgct acaaacagca
    50221 aacttcgtta taacacggca aatgctagaa caaaagatgg gaagcgacca ggtgcaaacc
    50281 gctttgatga aattcacgaa aatgaagatt attcaatgat aaatgtggct acttctggtg
    50341 gtggtaaaat tcgagattat agagaatttt atgatacaac taatggtcat gttcgtggtg
    50401 gtccgcttga tgacattata gaagaatcaa aaatgattct ttctggagaa cttggaattg
    50461 acaaggatgg agcagaattt tctagtttgt ttccatttat ttgtcgcttg gataacgata
    50521 atgaagttga tgatcccgac atgtgggaaa aagcttgtcc aactattaat tacaatgcag
    50581 atttaaaacg gaaaatgttt caagaatact ctcaaatgca acgtaatgct ggtttaagac
    50641 ttacgttcat gaccaaacga atgaacagac ctatggaaga tacacgattt gctgttgctt
    50701 catatgatga tgttctgcat acgaaagaaa aagaatttcc tgaaaaaatg gatgaagtga
    50761 taggaacagt cgattttgct gatagacgag attttgccag cgttgggttg ctaggaaaat
    50821 acgataaaga tgtttatttt acacaacata cttttatcca cgaatcagcc cttcgattac
    50881 aaaacatcaa acgagaggtt atagatattt ctatagatca aggaaaatca cagatcgttc
    50941 atggaaaaaa tatagaagct gattatattg taggttggtt tcttgaaatg agtaataaat
    51001 attatattaa aaaaatcgct atggatatgt accgtgcaaa aatattgaag cccgctttag
    51061 aagaagcagg ttttactgtg gaaattgttc gaagcggatc tgttacacat ggtatgttaa
    51121 aagatctggt tgatgacctt tttattaatc aacgtttatt ttttggtgac gatgcgatta
    51181 tgcgttggta ttgcatgaat gtatatgaag agcatatttc taatggaaat atacgctatg
    51241 aaaaaataga acctgaaact agaaaaacgg atggcttttt ttcattcctt catggtttga
    51301 attttttaga tgatatttat gattctgctc ctgtaacagt cacaaatagc tcagtagaaa
    51361 atacaggaac tggatttact cctctagtat tctaacttga aaggaggtga gaaagtgggg
    51421 atttttcaaa aggcggtagg atacttcaca aaaaaagcaa cggttccttt agaagaatac
    51481 ttttgtaaat tgcaagttga ttttgtgtat cgaaaatttg cgattgaaac ttgtattgat
    51541 ttgattgcaa atgcgatgag taaagcggaa ttcaagtcat atgaagatgg aaaaaataaa
    51601 aagaatgatc tttactatag gctgaatgta gctcctaata agaaaaataa tgcaacagaa
    51661 tttagaaaaa aactgatcag gagattaata ttctacaatg aagtattgat cgtttctccg
    51721 tctaataatt ctagcgaaat atttattgcg gatagttggg atgtcacaga atatgcattg
    51781 aaagatgatg tgttttctca agtgcaaatt aacaacatag tccttgatag agaatttcta
    51841 gaaagtgatg ttatctatat aaaatacgca gatcaacaaa ttaggcaact agtcgatgcg
    51901 tattatcaag cgtatgggaa actcatttct agtgccatga atgtttacaa gcgctctaac
    51961 gctcgtagat acgtactgaa agggaattta ttccgaccgc aagacaatac aacacaagat
    52021 caaatcaata aaatgatgac atcacaattt aaggctttta tggaagctga taatgcaggt
    52081 gcggtatttc aattacaaaa tgagtacaca ttagaagatt tcagcggaaa cttccaaagc
    52141 aattcaagag atataaaaaa cttaatagac gacatctttg agatgacagc agcagcgttt
    52201 cacgttccga aaaacctact aaagggagac atgagtgggt tatcggatca agtggacgct
    52261 tttttaatgt tcgaaatcat accgattgct gaacttattc aggatgcgtt taacgctagt
    52321 ctctatgaag tagaagaata cttgtcaggg aattttgtac gtgtggatac aactatgatc
    52381 aagattacta gcttcaaaga tttggttgac gctattgatg taggcattag aaatggagta
    52441 tttacaatca acgaaggaag agaacgcgtt ggaaatgatc gctctgataa ggcgatggca
    52501 gatgaaatat ttataactaa aaacaatcaa caagtatcga aaggaggtga ggcgaatgac
    52561 gacaatgaaa acatttctag cagtaaagaa tgaaggcgca gtaccgcaaa tttttattca
    52621 gggatttatt ggttctagtt ggttctttga agggaatact gacaagggaa tcaaaaatat
    52681 tttggatagt ctaggtgatc aagaagaaat tgaagtagta attaattcaa acggtggaga
    52741 cgtatttcaa gggattgcta ttgggaactt acttaagtca aataaagcaa aagttaacgt
    52801 tgtgattaac ggcttagccg ctagtgctgc ttcaattatc gcaatggctg gcgatactat
    52861 aaaaatctac aacaatgcac aattgatgat tcaccgcgct tccacatacg gagaaggaaa
    52921 tgtcgatgac ttccgtacga ttgctgacca actggaatca attgataaat cggtaaaggc
    52981 ttcatataaa acacgattca atggcacaga tgaagcattg caagaacttc ttgaaaaaga
    53041 atcgtttatg gatgcagaaa cagctttgag ttatggattg gtcgatgaaa ttatcgatgc
    53101 agaaaatagc tcaggtactg aagctaaaaa agaacaaagc gttgaagaaa ttttgaatga
    53161 cgttaaagaa aaaagagcag aaaaaattgc tgcatttaca gcagcattaa ataaaacatt
    53221 tggacaagga gatgtaaaat aatgacagtt aaaaatttaa aaggtgtaac agctgcaagc
    53281 gaccaattga tgaaagcttt taaagatggt aacgaagaat cttttagcgc agctatggta
    53341 agcttatcta aggaaattca ggataaaatt ttagaagaag caacagcaaa aaatcaagat
    53401 caattagtat taatgaaccg tggtcagcgt gtattaacta cacaagaaac aaaattctat
    53461 aacgaagtag tgaaaaacga aggttttgca ggggtcgaag aattagtgcc agctactgta
    53521 tttgaacgtg tatttgaaga tttagaacaa tctcatccac tattgcaaaa aattactttt
    53581 gttaacacaa ctggtgtaac agaatggatt gtgtcacgtg gagtcaatcc agcatggtgg
    53641 ggtaaacttt gcgaagctgt taaaaaagtt ttagataatg gctttgatgt aattaacatg
    53701 aagcagttca agctatcagg ttatattcct gtatgtaagg caatgcttga tttaggtcca
    53761 gtatggttag atcgttatgt ccgtactgtt ttagtagaat cattgagaat tgcattagaa
    53821 caagcaattg ttgatggtac tggtaaagat atgccagtcg gaatgatgcg tgacatgagc
    53881 aaacaaacta gcggagaata tgctgaaaaa aaagcagaac ctattacagc tttagatgct
    53941 gtaactatgg gcggtttgat ggcgcgacta tcaaaattca atatcgaagg tgtgaatgat
    54001 ccgatttatc gtaatgtgaa tccttctgat gtggtcctaa ttgtgaatcc aactgattac
    54061 tggtctaaag tattcccagc taagactgta ctaactgcta atggagaata cgtacaagta
    54121 ttgccagtac cagtttcaga tttgcagtca acggctgtgc cagaaggaaa agcagttatt
    54181 ggggtagcct cagattactt catgggtgta ggatctacac taaaaattga agcttcagat
    54241 gaataccatt ttgttgaaga cgaacgcatt tatctagcta aacaatatgc aaacggtcaa
    54301 cctaaacgta acgatagttt cattgtatta gatattagcg ctttgggaac tactactaca
    54361 actacaaaac caacaaccac aacaactaca acacaagcgt aggtgatcag aatgaagtat
    54421 attctttgtc agccggcaat caatcggttt aaatgggagc ttgaagtttg tttaactaat
    54481 ctgaagaaac taggaatcaa agatatcgta ttgcttttca gcagacacga tgatcagatt
    54541 cctatttttt ttgagaagga atatggtgtt gaagttcatg tgtacgatga tctgcgggac
    54601 gacaaagagt atattccttc gattaaacca tatttatggt ggaaatattt agaagaagat
    54661 cattcgcgtg aggacgaccg atatttctat atcgattcgg atgtcatttt caataaaaga
    54721 attaatttgc gcaaattgcc ttctaaagat gatgtttggt attgtagcga ctgctgtagt
    54781 tatctaagtc ttgattatat tagaagctgt gaaaacggag aaaatattct aaaagatatg
    54841 gcaaacattg taaatgttac agtagaatct ttggaaacta taaacactaa ttcaggaggc
    54901 gcacagtggg ttattaaccg tcctaaagcg aattattgga aaaaggttta tctggattct
    54961 aatcggctat atcgctacct tagagggcaa aaaacaaata tacaaatctg gacagccgag
    55021 atgtgggcac agctttggaa catgatgtat ttcaatattg gtcctaaagt tcacgaggaa
    55081 ttagactttt gttttgctac tgatccaata gaaaaagtta aagaagtaaa aatcttacac
    55141 aatgctggag taacaacaaa cgatgaagat ttatttttca aagggagata cgtgacttct
    55201 acgccttttg atgaagattt atcatttgta aacaagaaaa aatgctctta cgcatatgtt
    55261 aaagcaatta aggcggtggt tagatgacgc ctgaacaagt gactgaagaa ttgctaatag
    55321 ctgtgaagga taatatttac gttacctgga acgaagaaga tgagtcaatt aaaaagatga
    55381 tagctaaaaa tgctgtttat cttcaaagta aagtgagtac aacactttct ttttctcctg
    55441 aaagcttaga atacggattg ctaatcgaaa gatgtagata cgactggaat cgtgctttag
    55501 atgagtttga acaaaatttc gctagtgagt tattaggttt cattcaacat tatgcgctac
    55561 aagaatatat tgcaggtgat gtgaatggcg aataatcgta gactcgaaga aacattcaac
    55621 gatggttggt taaagatttt gacgcaaact accaaaagaa atgaactagg aaaaaagatt
    55681 ggtgtagaag atacagaaat cacttcttta aaatttagaa atctttccat gagagatagt
    55741 gatataacag ctatggatgc gatgggatcg aaattaacta agaaagtaaa gactccattt
    55801 catccaatcg ccaagaaatt taataaagat caatatttta tcgtaatcga tagtatgcgt
    55861 tacaacgtta tctatgccga ttacgataat ttttatatct atttttatct tgaaagtgtg
    55921 ggtgaatatg gtgattgata attctaaaga aaaagaacgt ttaaataagc aaatttctgc
    55981 tatcaaaact tccttagaag agcattttgg cctcaaactc tttcaagact ccgtaggcga
    56041 ggatgagcta cctgatgatt ttaattactt cattctcgaa acaggagaaa tagaaatgat
    56101 cactgagcca aaatatagcg tgggtcaaaa tctatatcta actttctatt cagaaaatag
    56161 agaagattta acaggagact cactagatat tatttcattg attcaaaatc gttcgattcg
    56221 ttttcagaga atggatccca atcatttaaa actagagaac caagatcgct atatcgatca
    56281 attggtattt acgtttagac gattattgaa gagtgattgt catggctaaa aatagttggg
    56341 agctaaaaat aaatggacat gatgaacttc ttgtgcggat ggaacgctat tcaagcgaga
    56401 gcgaacgact gattaacgaa gcattgaaat caaaaggttc ggctattgca gtggatagga
    56461 ttacagaaaa aattcctgtt tctgaagcag atttaagaag agggcaccaa cacgcaaaaa
    56521 atagtcgtcc acttaagact caatacatta atttgggttt catcattaga cctacaagaa
    56581 aatttgagta tttaaaatat cctgatttgg ggataggtac ttctaaaaga aatcagccgg
    56641 acgaatttat gagaagagga ttaggtcttg cacttgatcc aattacagaa cttctgattc
    56701 gtcaattcga taaattaaat aaataggggg aacaacaatg gctaaaacaa aaactgtagt
    56761 aacaacgttc gataacgtaa gtatcaaacg aattgctttt aattttaaga acgcaggaaa
    56821 tgcaatcgca acgaattgta acggacaatt agatggcgaa acagaaatgc aaacggtggt
    56881 taaaaaatgt ggagcgacag aagtaaaatc aaaatctaaa ccaatcaata tgacggtaac
    56941 aattactgca catgtaccga tggaagttta tcgacgtttc aatgggttga aacaagatgg
    57001 acgtattaaa ccaggcattt actcttacgg tcctgattcc gtaggcgaag atttctcact
    57061 tgctgcagag atcgtggatg acttcgaaga aaatagaaag ttagttggta tgttagcatg
    57121 cacttcgaat acaggattaa cattctctat tgaaaatggt gcggatgaag tagctgcgtt
    57181 agaactagaa acaaaagtta tgcaagatga atttggtaaa ttttatcatg aagcaattgt
    57241 tgcagaactt gaagaagact taacagatca atggatgacg aatctatctg ctgatgtgat
    57301 taaaaaaact tcagttgtga caactacggc cactcaatca cagtaaaaaa aacggaggta
    57361 gcgaaatgaa cgaagattac tcaaaaattg aactaaacga tggaacaatt ttgaatttag
    57421 aacctaaact gaatatcaag aaattattga tgatcaatag agattttaac acagacgagt
    57481 ttgcaaaaat gactgtggga aaaggatcca tggatatttc tgttattcaa ggtgcaaagg
    57541 ctgtgtatat tgcttaccgc caagcgaaca tgactgatta tatttcattc gatgaattta
    57601 tcgataaatg ggattttgat atggctactg ccagctatat ttatcaattg atgatgttca
    57661 aacaagcacg cgatgcttat caaaaagaat ttgaaaaagc aaataaggaa aaaaagcttc
    57721 aaaagtaaaa attccaaagc tcttagttga aacgtgggtc gatgtctatt cgatgttgac
    57781 cgacgttttt tctatgcctt cagatttggt tttaagcgat atctgtttag atgacatttt
    57841 gcaaatggct tacaacaaga gtgcttatga aggatggaaa aactatgcaa taaaccaatc
    57901 ccagaaaaac taaagaaagg aggtaaaaaa tggctaaaaa gagaacagaa gcagaagtaa
    57961 ctttcatagc taacgatgac ggattgaaat ctacgttaaa agaaatcagt gctgaattaa
    58021 ctaaaaatag agcagaatta aaactagaac aagctcaatt acaacagact ggttctgaat
    58081 cagacaagtt aggaagtaaa ttatcttctt tagaaaagca gtatgaatta caaagtcaaa
    58141 aagttgaagt aactagccaa cgtttagcca atgcgaaaaa atattatgga gaaaattcca
    58201 ccgaagttaa gaaacttgaa agagaactga ttaatcaaca aacagcgcaa caacgtttgt
    58261 caaacgaaat tgataaaacg agtaatgcac tagctcaagc aaaaggcgaa atacagacgt
    58321 acgagtctac aatgcaacag ttggatagcg aacaaaaaaa tgttcaagct agtgcttctc
    58381 tgattgaatc cgaatacaaa aaatggcaag caactgctgg tcaatcagct tctgaagccg
    58441 agaaattagc gaaagcccaa gaatatgttt ctcaacaatc tgaaaatgcg gagaaaacga
    58501 tagatatcct aagacgacag ttagaagcta cacagtctga atttggcgct acatccacag
    58561 aagcaatgca gatggaagcg aagcttaatg atgctgaacg tgaatttgaa gagttaggac
    58621 aagctgctaa aaatgtagat acaactaact tggacgatat cggaagcaaa atagatatga
    58681 ataatttaat ggaagcttct gacgttttaa gcgacattgg cgataagctt acagaattag
    58741 ggaaacaagc agtggactct gctaacagtg taggtagttc ccagagtaag atacaagcta
    58801 attttggttt gtctaaacaa gaggctgaag aattaacgaa tgtagccaga gacatttatt
    58861 ataaaggttt tggagaatcg ttagatcagt ccacagatgc attgattttg gtaaagcgta
    58921 atttaggaga tttaaataat caagatttac aaaatatcac ggaacaagct atggtcctag
    58981 aaaacaccat gggcgctgat atggatgaaa cgttacgtgg tgtaaatggc ttaatggtca
    59041 atttcggctt gagtgctcaa gatgcaatgg atttaatggt ttcgggtact caaaacggtt
    59101 tagataaaac gcacgaatta ggcgacaata tggcagaata tagccaatta tggagtcaaa
    59161 tgggatattc agctgatgaa acgttcggaa tgcttcaaaa tggtttagat gcgggtgctt
    59221 ataaccttga taaagtcaat gacttagtta aggaaatggg aatatcgtta acagatggtc
    59281 gatttgagca aaacatggat atgtttagtg aaagtactag aaaagctttt gaagagtgga
    59341 aaaatggcgg aggaacacaa aaagacgtta ttaattccat gattcaagat tttagcaata
    59401 tggatggtca atacgaccaa ttaaataaag cttcgacaat ttggtctgcg cttggcgaag
    59461 ataatgcgat gaaagttgtc caatctttaa ctgatgttaa ccatacattt gatgatgtta
    59521 gtggatctgc acaaaaaatg aatgaagatt ctactactcc gttgcaagag ttgaacggga
    59581 aaatagctga attaaaggat tcattagctc ctataggcaa cacaatcata gatgcactcg
    59641 aaccagtaat tgattttcta ggaaagatgg ctgatgcgtt taataatctt ccacaaccag
    59701 tacaggattt cattgttgct ataggtggtc ttacagcagc atttggcata ctgttaccgg
    59761 caatactagc cgtgtcatat ttatttggtc cgatgatgct tataattgga ggaattatag
    59821 ctgttatagc aggcgttatt gtggcaatta agaactgggg tgcaattact gactggttta
    59881 gtggtttatg gaaaaaattt actgattggt tgggtgatac ttgggaaagt ataaaagacg
    59941 gagcctcatc agtttgggat ggggttaaag aaacctggtc tggatttgta gattgggttc
    60001 aagatatttg gcaaggagtt tctgattggt ttggagagct atggagcgga ttagttgaag
    60061 gagcttccaa catctggcaa ggagtccaag aaacttggca aacattcgtt gattgggttt
    60121 caaatatttg gaacggagtc aaagaagtat ggtcgattat ttgggcagac attgtaggaa
    60181 ttgttcaaat accatggaca ttaataacgt cattgattca agctggtatt aatattatcg
    60241 tgggtatttt tgatgtagct ggacagttat tgggcgcagc ttggcaagct gtttggacac
    60301 ctatttctga tttccttaaa aatacttggg atactatgac acaatggata agtatcgctt
    60361 ggaatgggat tgtaactaca ttccatacta tatttgatcc agtagtggca tggtggaatg
    60421 gtatatggac agctattagt actacggctt caaatatttg gaattcaatt agtgcaacag
    60481 cttctagtat ttggaacagt atcaagaata caatcactag cttggtacaa gcagctgcta
    60541 cagtaattca aaatatttgg tcaactgtat ctagttggtt aggtggaatt tggaattcaa
    60601 tcagctctac agcatcaaat atctggaata gtgtgactag tagtataagc aatgctataa
    60661 acgcagctaa aagtgccatt caaagtgttt ggaatagtat atcttcgtgg attagcggaa
    60721 tttggaacgg tatcaaaaat actgctttga atctttggaa tggaattaca agcactatta
    60781 gctctaaagt aaacgatgga aaaaatgcaa tttcaagcgg ttggtccaat ctaacaggta
    60841 ttgtttccga catattcaat aatgttaaaa gtacaattgc taacatatgg gaaggcatca
    60901 aaaagactgt tagcgctcca attgattgga ttagagacaa aatcagtggc atttttgata
    60961 atttgaatat ttctatacca catattccgt taccggaatt tatcatggaa ggcagcttta
    61021 acccgctaaa aggtcaaatc ccccatttgc gtgtaaaatg gcatgctaaa ggaggtatct
    61081 ttactaaacc aactttacta ggtggaatga acggtgtcgg tgaagcagga cctgaagcag
    61141 ttttaccttt gaaaagatct gttttgcaag aaattggtga tcgtatcttg agtagcacat
    61201 cagtttcatc tagggcacaa acgattcaac ctgtgaataa ctacgaattc aatttcacaa
    61261 ttgatggtaa cgcagatgag gttactatga agcaaacaac tcaacaaatc attgatagca
    61321 ttacaaaaat tcaaaatgat aatgcttcgg catggcgtta aacaggagag tatttctcct
    61381 gtttttttag tattaaaaag gatgtgaaaa aatgactgat tgtatacatt ctataatcga
    61441 tggatttcct gattatttgc ataaattggc tttagctgaa agaccaacca taccttctcc
    61501 aaaaagacag agagttgaaa cttctgtttt aggtaggtta ggtggcttag tacaagatta
    61561 ctcgtttgaa gatatgtcgt ttacattgca ctataactat ttagaggatg tggaagacca
    61621 tcaagcgttc aagcaatcgt tttatatcat gcgtcattgg ttaaactatg caaagaaatt
    61681 agaattctct gacgatccca acgtctatta cgttatccag actatcgata ttggggatgc
    61741 agaaaacgat attgttgaat ggggagagtt cgatgtaaat attactgcga aaccattcgc
    61801 aagagttcaa gaagatgtac ctataaccgt agataaacca cagtcattta acttgctgaa
    61861 taatagttta gaagaaagtt ttccaaagat tatcatcact ccttcagcta cttcatgcca
    61921 gttcatctta aatgattatg tgtttagttt cgaaggctta gtagcaggaa ctgatgtagt
    61981 cattgatagt gatttgatgc tttgctacga agagcaatcg gacggagata ttttagatcg
    62041 gtccaacaaa atgaagacca tgcaatatcc gacattgcaa gtggatatca atcattttaa
    62101 ttgcactggt ttgagcaaaa tacaaattta tcgtaacggg ttaaggtagg tgaaatagat
    62161 gatcgataat ttaataacta tttacgataa aaatgacgcg aataatttag ctgaacattt
    62221 atatgatacg caaggtttag gcgctttgtc agactggtta acagctactg ttagcaataa
    62281 actaaacgga gccgagatat ttcagggtac ttattcaata aacggaacta atgcagattt
    62341 gattgtagaa ggacgtatta ttcagtgtta tgtagatgaa aatcgagcaa aacagcgtct
    62401 acggatttat tatgcaaaaa cttctgtaat aggcaatacg atagaagtaa aagctgaacc
    62461 tattttcaat gatataagaa aatcggtgtt gaataaatat gacagcggaa cagaaaagat
    62521 cactgctact caggcatggc aaaacgcaaa agttttagcg aaaccagcta tcccttcgca
    62581 gttttctttc tcgtcattag tagatacgct tgctaatgtg aagatagaaa aggcgaattt
    62641 tttagaattc tttggtggaa aagagggatc tattctagat cgatttcatg gtgagtttct
    62701 aaaagataat aacacattac gtcatgaaaa aagtctaggt acggatcata aaatcaaagc
    62761 gatttatact aaaaacttaa ctggtcttga cttagagatt gatgctcaaa gtgttttagt
    62821 tggagtttat ccattcatta gcagctcttc agaaggagaa gacgagatca ctctaccaga
    62881 agaagttatt ttcacggatt acgtggatga ttatcctgct ggatatgttt cttttgttga
    62941 ttttaaagac aaagcgactg atgtagccac attaagggaa gctgctaaag actggttgaa
    63001 aacaaacata gataaacaaa aaccacaagt gagtggttcg attgaattag taccattgag
    63061 gcatcaaaga ggctatgaaa aatttgttga tctagaaaaa gtttcgatgg gtgacggagt
    63121 agatgtgtat catccacagt taaaagtgaa tatgtcagcg agaattgtgg aatatacgtt
    63181 taatgttcta accaattcat acgataaatt agttgtagga aacgtcaaaa caaacttctt
    63241 agaaaacaca gagaataatg tcagcaattt gattaatgat gccattgatc aattgaaaaa
    63301 cggtggcgaa atcagtgatt tactcaatga tattgtagat catcaaactg atatgattac
    63361 tggtcaaaat ggtggttatg ttttattaga tcctaaagaa gcgcctagtc gtattttgat
    63421 tatggacaca ccagataaga ataccgcaag gaatgtttta caaatcaaca atgctggtat
    63481 tggtttttct aaaactggca ttaatggaac atatgaaacg gcatggacgt tagatggcgg
    63541 attcaatgcc tcgtttatta cggctggtga aatagtagga attactatta gaggtactac
    63601 attaattagt gatggtgctg attatagaac aagtattgct aatggcaaaa tgacttggta
    63661 ctcaaaaaaa gttaacaaag atattatgga gctagaagca cgtgattatg taagtgctga
    63721 tgccggtatt gtatcataca ccatgaaaac tggtggtggt ttcatgatta gaaatccaca
    63781 gggtaacttg gtttttagta cgtgggataa tggtaataac agaccgtttc tatcttttgg
    63841 tgcgcccaat ttcaggtata gcaatgctag ttatgtaact tctggcgacg gtagttcttt
    63901 aagcattaat ggtagtgcgg gtaactcatg ggaatttaag gtagctggta ggactatgaa
    63961 atttactagt gatggtatgc taacgttacc aggttgtttt tttggttcat gggaagatgg
    64021 gaaacttgct aggtttgaac aatcaacggt acaagtatat aaagatttta ctgttagagg
    64081 tactaaaaac tcaactgtac caacagaaca ttatggacaa cgactattga acgcttatga
    64141 aactccagaa tattatttcg ctgattatgg ggaagccgtt acaggtgaca atggtaaagt
    64201 tcgtgttgat attgacccca tgtttgctga aacagtaaat ctaagtcggt atatgacaca
    64261 tgtgacacct acagaactag ttttgtgtgc tgttactcat gaagatattg accatttcat
    64321 cattgaaact agtaagccaa acgtattagt tagatggaat ttagtggcac accgtctagg
    64381 gtatgaagat attagattaa aagaggatac agcatatgat agcacagtgc ttgaccaaaa
    64441 acgtttttaa aacgaagaca aggaggtata taaatggcta gcagtttata taatttggct
    64501 ttagatttca gcaaagaatt aaactacacc aaagctatta tggctcgtca aggtgataaa
    64561 gggattacgg tgacggttaa accgtttcta aatggcttgc agatggatac gagtggcgga
    64621 acatttactt taaaaggaac aacaccatct aaccgttacg tagataatgt tgcaactagt
    64681 gtaactagtg aagaagtcac gttttctctt gatggcacat ttatgagtga agcaggatat
    64741 tataaacact gctacgtaga atatagaaaa gacaatcaaa ttttaacaac gcaagatatc
    64801 atttttttct cactaggagt gtctgacatt tcgcaaggcc aagccgatga atatgtttcg
    64861 caattagaag agttgattcg aaagtacaac gaaacttttg atgcttttat ggctgaaatc
    64921 aaaggtagag tggatagctt aaatcaacag attactgatt taactggtca agctaaaacg
    64981 ctacaagaca agttagatgc tctgaaagaa gaaatttcta agttaggtaa cttacaagtg
    65041 atgtacagta acagcatcga cttcggggac tatgattatt cggagaaccc gaatttaatg
    65101 ccatatatta cagaaccttg ggttggacct ttgttaggta atggacatac agttaaagat
    65161 agtgttaaaa gggttataac tcatactaaa actagaacag ctaattccgg cgacatatta
    65221 tcgcttggct taggtattcc gtgtacagcg gaagctaata ataggtatct tataaccact
    65281 ttacgaccat ctacgacata cacattaagc gttactatga gtgtcggttc agattggact
    65341 ggagagacca atactatagg ggttaggctt agatatttaa atgaacaagg tggtatagaa
    65401 ctgcccatta atgcattaat accagcaaat gtagaacgcg ataaaatggt cactcataca
    65461 tttactggta taacaaaaga taatgtaact agcataacaa actgttatgt tgaaatattc
    65521 tcacttaata gtgaatataa aggaacggtt agtgtcagct atgacgttaa gttaaaagca
    65581 cactacccta acttactaga tggcccttac tggttaggta aagttccttt aggcgagaat
    65641 attgctgacc ctacagttgt ctttccacac aaaactagtg aatatatggt ttatggtaga
    65701 cgcaatacag aaaactatat cgctgaccaa acatatacca tatcaatgaa agcaactaaa
    65761 ctaacagttc aatcgtttgc cgtgtatatt gctgctggcc gcgttaaagt aggagacatg
    65821 aagcctactg aggggttagc taatacatgg gagttaactt ttactgtaac taagcaacat
    65881 atagatagtg gggtaactaa ttatctggaa atataccaat acccgtcagc tacaaaagga
    65941 gctgttcaaa ttgagtggct caaactagaa aaaggcaata ctcgaacccc gaatattagt
    66001 gagtataaat atcgtggtac tggtatgcgt gattcaaaca atccaaaaga ttatgtttgg
    66061 gatctagcac cagaatatgt cgaagataat ttggccacag atattaaaat ttctgaaatt
    66121 actggtaaag caaacaatta taccgatggg aaagtatcgg agattaattc gcagttgact
    66181 gcttcaatta atgaagtaga caccacagct aaggatgctc aaacaaaagc gaatgctaat
    66241 gcgactgcta tagatgaatt agacaataag atcgatgaac gcattaatga tacagctact
    66301 accacattaa cagttacaaa cgggaatacc ggatcagcaa agctttatcg tgaaggaaaa
    66361 acagtttcta tatattttgt ggctttaaac ggaaaaagca gtggtggaaa tgattcaacg
    66421 atactaacaa ttccagaagg ctatcggcca ccaattagtt ttgagcaact ggttggctcg
    66481 atagaccgtt ctactttgaa cagtgctcag ttatctattg gtgcagatgg agccattaaa
    66541 tggcgaagaa actcaagtta tggatcggat tatacctttg caattactta cacgatttag
    66601 aaaagcgtga atcgatatga aggcagcata tagaccaatt gaaccttacg gattcgagca
    66661 aatcattgtg aatgatgaag aacatttacc ggaagaatgc acagaagtcg aaccaccgat
    66721 tccaaattgg aaaccgaaat tcaattactg ggagggaaat aaatgaaaaa catttggaaa
    66781 tatggacgta ctggcggaga gtacgcagga aaagtattgg acgacatgct tgtatccgtt
    66841 ccttacacag atcagccacc gcttgaagga attcgtgctg atggcgaacc gttaacaatc
    66901 gctgatcaaa tgtttgatcc taaattgaat caatggatta ttttagcgaa cgcactagat
    66961 cacaacgatt taaacaatct caaagcaatg tatgagtcgt tagaaaatga gaacggcgat
    67021 ttaaaacaga tcaatgccaa actcatgcta agcgatgtag caattaaaca ggaaaatact
    67081 gcattgaaag aaaaagcgga tagtttagca caaatcaatt caaaaatgat gcttgcttcg
    67141 ttacaaaata gcaaagacat ttcagaaatt aaagagcaac taaatccagc ttcaaaggga
    67201 ggtgagtagt atgtttagtt ttagcgatgt gaaaatgatg tatgattggg gctgtttcac
    67261 taacgaacaa gtaatggttt tcgttccgtt gtgcattact gaagaaaaag cagataaaat
    67321 cattagcaaa gaagagagcg catcttaatt gatgtgcttt ttattttgat tcaaggagtt
    67381 gtcacatgat taatttaggg gaatggggag cgatagcagg atcaataacc gctatcgttt
    67441 ctttgatttt attagtaata aaaccaatta ctgcatcttt ctcgaagatt actgagactc
    67501 tttcaaaagt aagtcacaat ttagatttgc tgactaaaga tttagaatcg agcaaatcag
    67561 atcgattgat gattcatgaa gaactaaaga aacacgatga aagattagat acacatgcag
    67621 aaaaattggt agaacacacg caacaaatta aaactttatt tagggagaga agaaaatgaa
    67681 taataaaacg ttcgaagtac taaaatggtt cgcactggta attattcccg cactagctac
    67741 tttcgtgggg ttagttggta aagcgctcaa ttggcagtac acagatatct gtgttgtcat
    67801 cattactggt tttggcgcgt ttttagggag tgtgttgggt gtatcaaatc gaacctacaa
    67861 aatgttctcg gctgaaagcg aagaaggagg aaacaaatga aaaagaaaat tactattact
    67921 gcgatgagcc tgttaacggc tcttttttta ttacccatta atacgtttgc ttatactatt
    67981 aatgacgagt ataatttagc gccgaatcaa ggagactcca gattagcaat tcctaacaaa
    68041 attattttgc acgaaactgg aatagatgca ccagcaagaa acgtagccgc caacatgaaa
    68101 aataattata acggaagcaa tccttatact acagatgtta ttggtgacgg tgggattgtt
    68161 taccgtgtgg gtgagcaagg atatgtttcg tggggagctg gtaacgctaa tccttatgcg
    68221 cctgtacaga ttgaattaca gcgcacatat gataaagcat tgtttgaaaa aaactatcga
    68281 gcttatattg aatatacaag agatagtgca aaaaaatatg gaattccatt gactcttgat
    68341 caaggaactt ctttatttac aaaaggaatc atttctcatt tgtgggtgac aaattatgtt
    68401 tgggggaacc acacagatcc atatggttac ttatcgcaaa tgggagttag caaagaaaag
    68461 cttgcttatg atttagctca tggatttacc gatgaaaatc caacaacttc tgaaaacaag
    68521 cctgtcattg atccaacacg agctggtgca gctaatccta cgctgacaga tggaacaaat
    68581 cacgcccaca ttgatcagtt tggggaaatc gaaaacgcaa acttgcatgt ggctggatgg
    68641 cacattgcta actataaata cgagtatatt ttcattatgg actacaatac tgggaaagaa
    68701 ttagctcgag taagagctga tggaatttat agaccagatg taaaccaagc ttataatact
    68761 tctggaaatg ttggttatca tgtatctttc aatatgcgta attttcctag taagaaagtc
    68821 tatgtaatga tgcgggcaac gaatgatcca gagggaaaca ctaaaggcgg tgcgcaagat
    68881 ttccatgaca aacgttggta tttaaatatt cctaaacgat aaaaatagct cctcgttgag
    68941 gagcagtaca taactatatt gacaactata aaaattattc gataaaatag tgatgttatc
    69001 gcatatcttc actatcaccc ataaatagtc acactccaag ctatgcgata acaggtttgt
    69061 tgccacacat tctactggtt gattgtttat ggctttatgt ggcaacaacc agtaccctta
    69121 gctcagttgg tcagagcaga cggctcataa ccgtccggtc gtaggttcga gtcctacagg
    69181 gtacattaac gtagccattt gaatcgttct gtgttagaat ttttttgaag agtattatac
    69241 aagctaaagc ttttcttcat tgccactcaa atgagtggct tttttatgta tccttttatg
    69301 gattaatgaa aggatgtttc acatagttat acttctgtat atttgaaaag ttttactttg
    69361 atttttaaat agaaagacat ttgggttaaa ttgtgagata ataataaaga agagtttaaa
    69421 gcgcacccca aaccacttcc ccataagtgt gttacgcttt aaactctttt atatttgaag
    69481 ccattaaaaa gcataccata tttttgaaaa aaagtgagaa aaaaggctta caattggagt
    69541 ggtagttaat tagtgactta tttttgattt tatagcactg atactataaa atatagatat
    69601 catcatatta cacaatctta atactaactt aaaaaatatc tcctttcaca agtatggtga
    69661 taaaattcgt tccgggctac ctttttaggt agcctacttt aatctttata cctttctgga
    69721 tcaacgaaag tatactttat atagtcataa cgccgatgat cgctacgtgc gtccggcacg
    69781 tcagtc
//
LOCUS       DAXLPQ010000009        66578 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.009, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000009 DAXLPQ010000000
VERSION     DAXLPQ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.009"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..1283)
                     /locus_tag="ACF3UO_000784"
     CDS             complement(<1..1283)
                     /locus_tag="ACF3UO_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3656832.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKG"
     gene            complement(1581..2516)
                     /gene="murB"
                     /locus_tag="ACF3UO_000785"
     CDS             complement(1581..2516)
                     /gene="murB"
                     /locus_tag="ACF3UO_000785"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFD3656833.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2589..3509)
                     /locus_tag="ACF3UO_000786"
     CDS             complement(2589..3509)
                     /locus_tag="ACF3UO_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3656834.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3622..4374
                     /locus_tag="ACF3UO_000787"
     CDS             3622..4374
                     /locus_tag="ACF3UO_000787"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFD3656835.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5238..5771
                     /locus_tag="ACF3UO_000788"
     CDS             5238..5771
                     /locus_tag="ACF3UO_000788"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFD3656836.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6261..6785)
                     /locus_tag="ACF3UO_000789"
     CDS             complement(6261..6785)
                     /locus_tag="ACF3UO_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFD3656837.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(6778..7251)
                     /gene="tsaE"
                     /locus_tag="ACF3UO_000790"
     CDS             complement(6778..7251)
                     /gene="tsaE"
                     /locus_tag="ACF3UO_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFD3656838.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7374..8354)
                     /gene="pta"
                     /locus_tag="ACF3UO_000791"
     CDS             complement(7374..8354)
                     /gene="pta"
                     /locus_tag="ACF3UO_000791"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFD3656839.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8507..9187)
                     /locus_tag="ACF3UO_000792"
     CDS             complement(8507..9187)
                     /locus_tag="ACF3UO_000792"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFD3656840.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9313..10182
                     /locus_tag="ACF3UO_000793"
     CDS             9313..10182
                     /locus_tag="ACF3UO_000793"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3656841.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10208..10723
                     /locus_tag="ACF3UO_000794"
     CDS             10208..10723
                     /locus_tag="ACF3UO_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFD3656842.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(10770..11333)
                     /locus_tag="ACF3UO_000795"
     CDS             complement(10770..11333)
                     /locus_tag="ACF3UO_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3656843.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11388..11567)
                     /locus_tag="ACF3UO_000796"
     CDS             complement(11388..11567)
                     /locus_tag="ACF3UO_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656844.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11644..12153)
                     /locus_tag="ACF3UO_000797"
     CDS             complement(11644..12153)
                     /locus_tag="ACF3UO_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656845.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12249..12629)
                     /locus_tag="ACF3UO_000798"
     CDS             complement(12249..12629)
                     /locus_tag="ACF3UO_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3656846.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            12959..13708
                     /gene="pnuC"
                     /locus_tag="ACF3UO_000799"
     CDS             12959..13708
                     /gene="pnuC"
                     /locus_tag="ACF3UO_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFD3656847.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(13892..15169)
                     /locus_tag="ACF3UO_000800"
     CDS             complement(13892..15169)
                     /locus_tag="ACF3UO_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656848.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15248..15892)
                     /gene="pcp"
                     /locus_tag="ACF3UO_000801"
     CDS             complement(15248..15892)
                     /gene="pcp"
                     /locus_tag="ACF3UO_000801"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFD3656849.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16091..17035)
                     /locus_tag="ACF3UO_000802"
     CDS             complement(16091..17035)
                     /locus_tag="ACF3UO_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFD3656850.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17037..17723)
                     /locus_tag="ACF3UO_000803"
     CDS             complement(17037..17723)
                     /locus_tag="ACF3UO_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFD3656851.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18197..18517
                     /locus_tag="ACF3UO_000804"
     CDS             18197..18517
                     /locus_tag="ACF3UO_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFD3656852.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18671..19576
                     /locus_tag="ACF3UO_000805"
     CDS             18671..19576
                     /locus_tag="ACF3UO_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656853.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19573..20346
                     /locus_tag="ACF3UO_000806"
     CDS             19573..20346
                     /locus_tag="ACF3UO_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3656854.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20527..21951)
                     /locus_tag="ACF3UO_000807"
     CDS             complement(20527..21951)
                     /locus_tag="ACF3UO_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFD3656855.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22162..22608
                     /gene="nrdI"
                     /locus_tag="ACF3UO_000808"
     CDS             22162..22608
                     /gene="nrdI"
                     /locus_tag="ACF3UO_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFD3656856.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(22673..24655)
                     /locus_tag="ACF3UO_000809"
     CDS             complement(22673..24655)
                     /locus_tag="ACF3UO_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFD3656857.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24669..25565)
                     /gene="murQ"
                     /locus_tag="ACF3UO_000810"
     CDS             complement(24669..25565)
                     /gene="murQ"
                     /locus_tag="ACF3UO_000810"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFD3656858.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25568..26629)
                     /locus_tag="ACF3UO_000811"
     CDS             complement(25568..26629)
                     /locus_tag="ACF3UO_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFD3656859.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(26840..27367)
                     /locus_tag="ACF3UO_000812"
     CDS             complement(26840..27367)
                     /locus_tag="ACF3UO_000812"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3656860.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(27434..28936)
                     /gene="eat(A)"
                     /locus_tag="ACF3UO_000813"
     CDS             complement(27434..28936)
                     /gene="eat(A)"
                     /locus_tag="ACF3UO_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFD3656861.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29194..30315)
                     /locus_tag="ACF3UO_000814"
     CDS             complement(29194..30315)
                     /locus_tag="ACF3UO_000814"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3656862.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30441..31382
                     /locus_tag="ACF3UO_000815"
     CDS             30441..31382
                     /locus_tag="ACF3UO_000815"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFD3656863.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31532..32428)
                     /locus_tag="ACF3UO_000816"
     CDS             complement(31532..32428)
                     /locus_tag="ACF3UO_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFD3656864.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            32697..34037
                     /locus_tag="ACF3UO_000817"
     CDS             32697..34037
                     /locus_tag="ACF3UO_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3656865.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34255..34698
                     /locus_tag="ACF3UO_000818"
     CDS             34255..34698
                     /locus_tag="ACF3UO_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFD3656866.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35202..36620)
                     /gene="nhaC"
                     /locus_tag="ACF3UO_000819"
     CDS             complement(35202..36620)
                     /gene="nhaC"
                     /locus_tag="ACF3UO_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFD3656867.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37023..38246)
                     /locus_tag="ACF3UO_000820"
     CDS             complement(37023..38246)
                     /locus_tag="ACF3UO_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3656868.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38277..39116)
                     /locus_tag="ACF3UO_000821"
     CDS             complement(38277..39116)
                     /locus_tag="ACF3UO_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3656869.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39133..39813)
                     /locus_tag="ACF3UO_000822"
     CDS             complement(39133..39813)
                     /locus_tag="ACF3UO_000822"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFD3656870.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(39815..40888)
                     /locus_tag="ACF3UO_000823"
     CDS             complement(39815..40888)
                     /locus_tag="ACF3UO_000823"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFD3656871.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(40944..41182)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41225..41458)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41535..42206)
                     /locus_tag="ACF3UO_000824"
     CDS             complement(41535..42206)
                     /locus_tag="ACF3UO_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3656872.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42293..44941)
                     /gene="mgtA"
                     /locus_tag="ACF3UO_000825"
     CDS             complement(42293..44941)
                     /gene="mgtA"
                     /locus_tag="ACF3UO_000825"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFD3656873.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(45283..45457)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            45630..46067
                     /gene="ndk"
                     /locus_tag="ACF3UO_000826"
     CDS             45630..46067
                     /gene="ndk"
                     /locus_tag="ACF3UO_000826"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFD3656874.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46089..46955)
                     /locus_tag="ACF3UO_000827"
     CDS             complement(46089..46955)
                     /locus_tag="ACF3UO_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3656875.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(47115..49208)
                     /locus_tag="ACF3UO_000828"
     CDS             complement(47115..49208)
                     /locus_tag="ACF3UO_000828"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3656876.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(49957..50580)
                     /locus_tag="ACF3UO_000829"
     CDS             complement(49957..50580)
                     /locus_tag="ACF3UO_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656877.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHVGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(50739..52136)
                     /locus_tag="ACF3UO_000830"
     CDS             complement(50739..52136)
                     /locus_tag="ACF3UO_000830"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3656878.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(52168..53139)
                     /locus_tag="ACF3UO_000831"
     CDS             complement(52168..53139)
                     /locus_tag="ACF3UO_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3656879.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            53513..53938
                     /locus_tag="ACF3UO_000832"
     CDS             53513..53938
                     /locus_tag="ACF3UO_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656880.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(54426..55127)
                     /locus_tag="ACF3UO_000833"
     CDS             complement(54426..55127)
                     /locus_tag="ACF3UO_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3656881.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(55143..55583)
                     /locus_tag="ACF3UO_000834"
     CDS             complement(55143..55583)
                     /locus_tag="ACF3UO_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFD3656882.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(55583..56158)
                     /locus_tag="ACF3UO_000835"
     CDS             complement(55583..56158)
                     /locus_tag="ACF3UO_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFD3656883.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            56399..56608
                     /locus_tag="ACF3UO_000836"
     CDS             56399..56608
                     /locus_tag="ACF3UO_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFD3656884.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(57006..57518)
                     /locus_tag="ACF3UO_000837"
                     /pseudo
     CDS             complement(57006..57518)
                     /locus_tag="ACF3UO_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(57644..58345)
                     /locus_tag="ACF3UO_000838"
     CDS             complement(57644..58345)
                     /locus_tag="ACF3UO_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3656885.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(58453..59895)
                     /locus_tag="ACF3UO_000839"
     CDS             complement(58453..59895)
                     /locus_tag="ACF3UO_000839"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3656886.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(59909..61774)
                     /locus_tag="ACF3UO_000840"
     CDS             complement(59909..61774)
                     /locus_tag="ACF3UO_000840"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3656887.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(61895..62746)
                     /gene="licT"
                     /locus_tag="ACF3UO_000841"
     CDS             complement(61895..62746)
                     /gene="licT"
                     /locus_tag="ACF3UO_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFD3656888.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(63056..63769)
                     /locus_tag="ACF3UO_000842"
     CDS             complement(63056..63769)
                     /locus_tag="ACF3UO_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFD3656889.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(63837..64163)
                     /locus_tag="ACF3UO_000843"
     CDS             complement(63837..64163)
                     /locus_tag="ACF3UO_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFD3656890.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(64286..64513)
                     /locus_tag="ACF3UO_000844"
     CDS             complement(64286..64513)
                     /locus_tag="ACF3UO_000844"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFD3656891.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(64835..66088)
                     /locus_tag="ACF3UO_000845"
     CDS             complement(64835..66088)
                     /locus_tag="ACF3UO_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3656892.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            66149..>66578
                     /locus_tag="ACF3UO_000846"
     CDS             66149..>66578
                     /locus_tag="ACF3UO_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3656893.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGS"
BASE COUNT        19302 a        13854 c        11476 g        21946 t
ORIGIN      
        1 cctttcactt gagaaataat gtaatcggta taagcagatc cttgcgaaaa atcaatacag
       61 acatgaatcg gtgcttcaaa atatgatacc ggacaaatac cgaccaataa aaagagataa
      121 tcataaaata agcgaatcat gaaacgttca tcttttccca agaaatagcg tttattctct
      181 tgtatgacct tttggattgc tgtactgaat attggatacg tctcgaagaa aaactgtagc
      241 tgctttttag acgtaaagct agtcatctca aagtcgaata tccaattttt tcgattgaca
      301 tgcatcatac ccatacgaag ttcttttcgt atatatagtc tttcttcttc agagatttca
      361 atcgaaaatg gtaattgatc aatcaattcc actgacattt tttgactaat catgtggata
      421 tcatgaaaat gagcttccgc aagtccaaat gcgccatcta attcaaattc ttcttccgtg
      481 atcaaaaaca acatgatata agaaatctca tcaatgatct gctctttagg gatatgaaga
      541 aaagaaatat gtgataaatc cttgatgatc ttcattcctt ctgagctctt aaagtattca
      601 tctgaaaaga aacgttttcc gattggttga ttcccatagg ccctcaacaa actaatagtg
      661 gttagcaaat tgaatttgat tcgttttgtt gcagacagtt ttaaattgaa cagatattca
      721 aaatattgca cgatactctt tgcttcattc atgacgcttt ctctaaatgg catagaaaaa
      781 ccattaaaga ccccgaaata taccccaaat aatacgttcc gtatgtttat ttcttcccca
      841 actaatatgt ttttctttaa ctttatttga tgctgttcaa gaaaagagac taattctctt
      901 ctttttacat aggctcttga tatgcttaaa aaatgattct ctgcaaattt ttcgatcgtt
      961 acttttgaat ccacgatctc cgttaacagt cgagcaattt ttgatcgttg aaagtagatt
     1021 cttcttaaat ttttgatatc cgtcaaattc agacgttcga catggatctc tgcttcttct
     1081 gaaatttgga tctctggctt tgttttgaat tcagtaaatt ctttatttaa ttctatgata
     1141 taatttcttg ttttaaattt agacaaacct aatgtttcat ataacttagg cagcactaca
     1201 taattctttt tctcaaattc taaatatcta gctagcagca gtttttctct atcttcctct
     1261 tctataaggt aatccaactt catatcctac acctcaaaaa atgcctcata ccaattactt
     1321 gatatgcaga tgaaagttca tcttttcacc tatactgatt ttatgatgga ttatgcttgt
     1381 tttttcatca gttattctca ttttttatct tttttttgag aatattgcaa aaaatggaaa
     1441 aatttatgag gaaatattct atattttttg ttttattgtg ttaaaatgta caagatttgc
     1501 gccatttgcg taaacaacca caaaaaagag caggacggcc accgtcctgc tcttttactt
     1561 attttaagtt ccattactta ttaattggct aaacttctgc ttgtttctga tattgcttgt
     1621 ttttctccaa tgatccgcac ttctgtttct aaagacacat caaatttttc tttgattact
     1681 tcttggatgt gcgcaatcaa ttcaatataa tctgtcgctg tcgcatgatc gatattgacg
     1741 atgaatccag catgtttttc agagacttgt gcaccgcccc atttcaggcc ttgcaatcct
     1801 gcttgttgga tcagctgacc tgtatagtgt cctactgggc gcttaaagac acttccgcat
     1861 gaagggtatt ctaatggctg ttttgattga cgcaattcgg tcaactcatc cattcttgct
     1921 ttgattgctt cataatcccc tgtttgcaaa ctgaatcgag cttccaatac gatagcacgt
     1981 aattcttgga ctttactgtg acgataagaa aataccattt cgtcttttgt caaagttttc
     2041 aatgttccat cttcaagcaa aagatccact tcagcaaaaa catctttgat ctctccgcca
     2101 tacgcacctg cattcatata aaccgctcca ccgacacttc ccgggatgcc gcaagcaaat
     2161 tcaaatccag tcaatgattc tgccaaagct gcataagtcg tatcaatcag tgaggcacct
     2221 gcttccgcaa tgaccatcgt tcctttgaca tgaatctgtt tcatttcagt cagcatgatg
     2281 actacaccgc gaatcccgcc atcttgaacg atcagattgc ttgcatttcc taataccatc
     2341 caaggtatat catggattcg gcaataatcg atgatttgct ttacttcttc ttgttttttc
     2401 gggaatgcaa ggacatcagc tggtccacct gttttcgtaa acgtatagtt catcaatggt
     2461 tcatcaaaca atatagtaat cgtggctaag ctttcaacta tttcttcttt attcactgag
     2521 gattttcctt tcttttctca aacgtcctca ttattctatc acgcttaata caatcttgcc
     2581 agtcttgttc aaagttgatg acggtagtga tctttaagca cttcctcaca taattcatga
     2641 cttcttacaa cttctttttg tttaagcaat tctgtttccg atttacctaa acggatctga
     2701 gaaaagaagg cctctaccat tggctcaaac ccgcgtttga ctagcgtgtt tgtccagtcg
     2761 ccaaattctt tcactttttt tccatcagca tcttgaatga caagctgggt cagatcgttt
     2821 acttcataag taccattttt acttgttact tgatattttt ctatattagc gccacttgct
     2881 aaatccatcg ttaaaatagc cgtttgattt tgtgtttcta attgtaaaat ggcatattcc
     2941 aaaaattcct ttgtttctct tatctggtat tttgttctca aaatgggttc atctaataaa
     3001 tacacagctg tatcaataag atgtaaaaac aaatcataaa ggacgaactc tgtcgtttct
     3061 tttgccgcta ttcgattttt ttgcaggtgg atcaaccgct tatctgggat acgtttcaat
     3121 tcttctacca taggagcaaa gcgccggttg aaaccgatca tcaaaattat ttggttctta
     3181 tcagctaatt cttgcaattc acgaacttca tttagatgga cactcagtgg tttgtcaata
     3241 taaacatgga taccattttc tagacatttt ttggctaatt cataatgtac ttttgttgct
     3301 gcgtggatca tacatgcttc gattttttct tctaaaagct catcgatcgt ttcatataga
     3361 tgttggaacc cgtactcttt ttgaattctt tcttttgttt ctttatttct tgttgcaaaa
     3421 taaaaatcaa gtgttccttg ttttttcgca taagttggta aatatgcttt ttctgcgata
     3481 ttccctacac cgattacacc aatcttcatc tactttcctc ctggatcatt tagttacttt
     3541 catcttacac cattttttac taaaatgagg tacaatagta tcgcaaaggt aaggaaatta
     3601 attcgaagga gtgtgctttt attgaaattt atctcttgga acgtaaacgg gcttcgtgcc
     3661 atcgtaaata aaaatttttt agaagttttt catgagttag acgccgattt tttctgtctg
     3721 caggaaacga aactccaagc aggacaaatt gatttagatc ttccaggtta ttatcaatat
     3781 tggaattacg cggaacgaaa aggctattcc ggcacagcga tttttgctaa aaaaccagca
     3841 ttgaatgcca cttacggaat gggtatcgat atccatgata cagaaggccg tctgattact
     3901 ttggaatatt ccgatttctt tcttgtaacc tgttacacgc caaattctca aagcgaatta
     3961 aaacgtttag attaccgatt agaatgggaa gaagcctttt ataattattt ggaaaatcta
     4021 aaaaaacaaa aaccagtcat cgtgtgtggg gatctaaatg tcgctcatca aaagattgat
     4081 ttgaaaaact ggaaaacgaa tcaaaaaaat gctggattca ctccagaaga aagagcggct
     4141 ctttctcgac tgttggataa cgggtttatc gatacattcc gttattttta tccaacccag
     4201 gaaggtgtct actcttggtg gaactaccga ttcaattcaa ggaaaaacaa tgctggttgg
     4261 cggatcgatt actttttgac gagcaaagat ttagagccag gactagctga tgcaaagatc
     4321 catacggaca ttatgggcag tgatcattgt ccagtagaat tagatttgaa ataaagaggt
     4381 tgtgaaaaag tcgtttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
     4441 ttttgcataa atttggcata ataccgagaa actggctttt gaacactgtt tatcgagaga
     4501 ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
     4561 atttttcgtt tggttgggct tattaccgca gatacaagct tttgaacacc gtttattaag
     4621 aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa aatagttcct
     4681 catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttatt
     4741 aagaggttgt gaaaaagctg cactgcatca agtaataaga acagccaaac aaaaatagtt
     4801 cctcatattt ttcgtttggt tggacttatt accgcagatg caagcttttg aacaccgttt
     4861 attgagaagt tgtgaaatca gcgtcctgac ctgagtatta gagaaacaaa tggcaaaata
     4921 gttcctcata ttttgctatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
     4981 tagtggagaa gttgtgaaaa agtcgcctac tttcgagtcg taagaaattt ttttgaaaat
     5041 ggttcctcac aactttgcat aaatttgact taataccgag aagtcatgat ccccatctaa
     5101 ctccaaatca caaggaatga gttcaaaaac tagcttttct caacaaatat tacataaaaa
     5161 attctatgtt ttttgttaaa tttatttgct tttttcaaaa gtatgttaca gtaatttccc
     5221 aaggaggttt tacagaaatg aattttgttg ccatggattt tgaaactgcc aatcatcagc
     5281 cttatagtgc ttgttctctt gcgctagtca tggtaaaaaa tagccagatc gttgatgaat
     5341 tctatacatt gatacagcct gagactcctt ttttctggcg aaatgtccaa attcacggaa
     5401 tccatcaaga agacgtacgc aatgcgccga aattcccaga agtctggcaa actatccaac
     5461 catattttca aaaaaatcgt ttagtcgttg cacataatgc tgcttttgat acaaaggtct
     5521 tagcgggatg cttagattat tatcatcttg aacagcctaa ttatctttct ttatgtacag
     5581 tgaaaagtag ccgtcgcctg tttcctgaat ttccaaatca tcgattgaac actgtgtgcg
     5641 aaaatttgaa catccaatta gatcatcacc atgatgcatt ggaagatagt cgtgcatgtg
     5701 cggaaatcct gctttatcaa gaaaaaaaat tcgggacaga tccattgaaa aaacttgtga
     5761 ctataaagta aaagaatact tatgaaacac acaaagaggt cgtgagcctg ccgtttcact
     5821 ccgagtcaca aggagcaatt tcaaaaaata gcttctcatg tttattaaat attgtgactg
     5881 gtgaccgagg agctggcagg agaacaccgt ttattggaga ggttgtgaaa aagctgttct
     5941 gcatcaagta ataagaacag ccaaacaaaa atagcttctc atatttttca tttggttgga
     6001 cttattaccg cagatgcaag cttttggaca ccgtttacca agaggttgtg aaatcagcgt
     6061 tttgacctga gtattagaga aacaaacggc aaaatagttc ctcatatttt gccgtttttt
     6121 gagctaatac cgaaggtcag ctgattgaac accgtttatt caaaaaaaat ggactgcgac
     6181 acgacttttg tcacagtccc ttcgtgtgtt tttctgcctt ctcaaaagga tgacagtttc
     6241 tcactctttt cctatttctt ctattcaatc aaataactca ttttatatac atctaaaaat
     6301 tcacctagat ctgttcttgc ccctctaggc atgaccgctt cgatttggaa gcccattttt
     6361 cggtaaaggt gtacggctct ttcattacga acttgaacgt caagctccaa tcgaaaaagt
     6421 acacccattt ccttcgccca actgatgatt tcttctagca taagagtgcc tagtcccatt
     6481 ccccaatatt cctgcagaat actgataccg acttctccca cgtgagacaa acgaaattga
     6541 ctgtctgcct tgacagatgc tgttccaata atcgtccctt catagattgc aagcagcaat
     6601 aaattattat tgctttcgta tatataatcc aactcttctt ctaaggtttc tggtggtaac
     6661 aggagttctg cttcatccaa aactaaaaat tctgtctcct tattaacttg tcccatcatc
     6721 aaaagaatgt cttttgcatc tcctggcact gcttcccgca agatgatccc aacttcttca
     6781 ctcatgattt tcagcccatt tttctagaat tcgctgtttg aaggtttcac tttgctcccc
     6841 gtatgagatt agtttcacat accgcttttc taaatctgta tcactttttt ctaaaatcag
     6901 ttccaaataa tcctccggca gtgcttcttc taatagattt ccccattcaa caacggaaag
     6961 cccatcacct tcaaaatatt catctaaccc taaatctgct ccgctagctg ctacccgata
     7021 aatatccata tgatacaacg gaatccgacc ttgactatat tctctaataa tcgtgtatgt
     7081 cggacttttg atcatttgcg ttatccctaa tccttgggca attcctttcg tcaacgttgt
     7141 tttacccgca cctagatcac cagtcaatat cagattgtca cctggcattg cggaatgacc
     7201 aattgcctct gcgaattgtt ctgtcattgt taatcctgat agttcgatca tttttcatct
     7261 tctcccgctc ttctttcttt ttgccagtat atcgcgtaat gaagtttttt taaagaaaaa
     7321 atgaactagt caagaacagc agctgctgtt tttggctagt tcgcgtgtat ttgttaatca
     7381 atcaatgttt gtgctgctgt gataatcgat aatttatata catcttcttc atttgctcca
     7441 cgagacaaat cagaaaccgg tttgttcaag ccttgtagaa ttggtccgat tgcttcaaag
     7501 ttaccgaaac gctgagcaat tttatagccg atatttcctg actgcaattc tggaaataca
     7561 aagactgttg cttgaccagc tacttctgaa tctggcgctt tcagttgtgc aactgaagga
     7621 acataagaag catcaaattg caattcgccg tcgatcatgt attgtggcgc tagtttttta
     7681 gcgattttag ttgcttcaac tactttgtct acttctggcg atttcgctga gccttttgtc
     7741 gagaagctca tcattgctac ttttggttcg atatcgaaca attctgctgt ttttgcagaa
     7801 tctacggcga tttcagccaa ttcttgcgca gttggattca cgttgatcgc acaatccgaa
     7861 aagacatatt tttcttgatc tcttccacgt accatgatca tcgctccgct tgtccgactg
     7921 atgccaggct ttgttttgat gatctgaagt gctgggcgaa cagtgtcgcc agtcgaatgg
     7981 atcgctccag agaccattcc gtctgcaatc cccatatacg taagcatcgt accaaagtaa
     8041 ttcacatctt ttaaaatctt ttctgcttgt tctttggatg cctttccatt tctacgttca
     8101 acaaaagtat ccaccatttc atcccactta tcgtaattat cagggctgat gatcgtaaag
     8161 ctagatgttt tgattcctct ggcatgcgct gcatttctta tttcttcttc gttccctact
     8221 aaaatgggtt ccacaagttc ttctgctttc aaccgggcag ctgcgcctaa aatacgagca
     8281 tcagtagctt ccgggaaaac gattttgatc ccacggcgaa caattttaaa tcttaaacta
     8341 tcaaacaatt ccacaagatg acctccagac gtttttatat gtattatcat acactattcc
     8401 agaaaaaaag aacagtttat tttatctgta tcagtcaaaa atgctggaaa aattaagttt
     8461 ttcacataca aagcgaactg cactataaca ggaaagcgct gttttattac actgtttcag
     8521 gcagttgcca atcaatcggt tcttctccta acgcaaggag cgcatcattc gttttcgaga
     8581 agggtttgga accaaaaaag ccacgacttg cagataacgg actgggatgt ggagatgtta
     8641 tgatgatatg gcgactctta tcgatcattt tgattttttc ttgtgccggt tttccccaca
     8701 agataaacac gattggtttt tcccgttcat ttaatttttc aatgatcgtg tctgttaatc
     8761 tttcccaacc tttcccgcga tgagaatacg cttgcccttc ccgaacggta agaacggtgt
     8821 tgagtaaaag gactccctgt ttagcccatg acactagatt tccatgttga acaggtgcga
     8881 ttccaagatc atcataaagc tctttataga tatttcttaa cgatggcggg atctttacgc
     8941 caggttgcac agaaaaagat aagccatgag cttgattttc tccatgataa ggatcttgtc
     9001 ctaaaatcac cactttaact tcttcataag gagtcaattc caatgcttca tagatatgat
     9061 acatatctgg atggatcttt tgggacgcat attctttttt taaaaattct cttagatgca
     9121 gataataatc ttttgaaaat tctgaggaca aaacttcttg ccaactgtta tgaatgattt
     9181 ctttcaaaaa ctccacctcc taataaaaag aataactcac attttcttca atcacaaggg
     9241 acaatcttca ccctcagcac ttgattaata tggtaaacta ggaacaagaa gcagaaagga
     9301 acgataatca ttatgatcaa attaattgca tcagatatgg acggcacatt attagatgcc
     9361 catatgagtg tttctcctga aaatgccgag gcgatacgtt ttgcaaatga tgccggtgtt
     9421 gagttcatgg tcgctactgg tcgaaactat caagaagctc gcgcagcttt agatgaggta
     9481 ggaatcgatt gtgcgatgat cactttgaac ggggcacagg tatttgataa agaaggaaat
     9541 tcattgttta ccgtgtcgat tccaaataat caagcaatct ctgttttaga tattctagat
     9601 gctaacggta tttactatga agtagcaacc aacgatggtc tttattctga aaatcaagcg
     9661 aaacgaattg aaagttttgc ttccatggtg gctacccatt tacctcacct tacgtataaa
     9721 atggcgattg ccatggcctc agctaagctg gagttattgc acatcacata cgtggacagt
     9781 attcgtgcta ttttggaaga aaagaatctg gaagttttaa aaattatttg ttttcataca
     9841 gaagggccag ctgtattagg tccagttgga aagcagattt ctcttttagg cgatctagcc
     9901 gttacttcct ctggtcaaaa caatatcgaa gtgaaccata aaaacgctca aaaaggaatt
     9961 gctgttgccc atgtcgctca cgagcgtggg atttctttag aagaagtcat gacgattggc
    10021 gataacttca atgatgtcag catgctgcaa gtagcaggag tcagtttcgc aatgggaaat
    10081 gcagaaatcg aagtaaaaga ttatgccaaa tatacaacgg acacaaacct tgaatctggc
    10141 gtaggaaaag ccatattgcg cgcgattgca gaagacttgt agttttatct agaaaagagg
    10201 gatatagatg tcagaatttt tcattcagga aaagcagctt ggacgtgcaa ctcggacaat
    10261 tgtcaaaaac gaaaaaggac attccctgtt tttgatggtt ggtcgctggg gaacaaaggg
    10321 cgatgcattg tctctttatg ccatgaatgg cgatctcgtt gctcacatca agcagataag
    10381 cctgacattc ggtacgcgtt ttgagctgta taaagagttc gaaaaggtgg gaaccatgca
    10441 gaaaatattc aattggcccg gtgactttta ttatattcgt agacttcact ggacagtcca
    10501 aggtgatatc tataatcatc aatatcaaat ccatcatttc aatcagcaaa tcatgaaaat
    10561 ggataaagca acactttttt caggagatta ctatgtattg gatgtctcaa atgatgaaga
    10621 tgctccagtt tgtatttgta ttgctgcggt tttagattac tggctctacc gtaaagacaa
    10681 aagtcgcgat aagcctgttt cttaccgact taacttaagt taaaaagatg tacctgaaat
    10741 gcggaaatac gcatttcagg tacatctttt tagatattct tttgcatatg atcataaaga
    10801 tgaccactga tcatccgctg accgacaact ttgaagtcat ggcgttcgta taatttttta
    10861 gcctttggat ttttttcatc cacacttaga ccgatgacgg agcgattagc tttcttcgcc
    10921 aatttaggta atgcttctaa taatcgcgaa ccgatgcctt gtcctctaaa atcttctgat
    10981 acactgatag agtccaaata ccattcgttg ggaaacgttt ctttatcaat gaacaaacgt
    11041 gtagacgcat ctagctgata tttctctaag ataggtacca gtggctgatc gatgattgat
    11101 tcttcttcat ctgtataacc gtaagcaact cctgcaactt taccgtctat ttcttctacg
    11161 atacctcgtg aataactgta acgataattt ggatcagtga ttgcttcttc taaaatctct
    11221 aaagtctttt gttcccctgt ctgcttcaaa aatggcagtt ccatatcttt tagaatcact
    11281 aagatcaatg gggcgatttc tggagcatct tcttttctcg caaaacgaat catagtttcc
    11341 tctccttttc tccattctaa catgcagaaa aagaaatcgc aaaatcgtta ttttaaaaaa
    11401 tcttcaatct tttcagtaat gaaataacca tgagtaacga ttcttgccgc ttcagttcgg
    11461 caataagggc agacgactgg catttcttta tcattatgtt cgactacatt attgacttct
    11521 tcgtatgcaa atttttttcc gcaattaggg catttcattt tttccatgtt atctcaactt
    11581 cctttcatct ttactctctt agcttactct tatattgtaa aaaagagaag caatatcctt
    11641 cttctatgca gatatccata cctgacggtc ctgttctcca tctattaatc ggactttata
    11701 ataaggacgt tcatctttga ctagaagtgt ccactctttc acttttgctt ttttcccgta
    11761 gtagctgact gcttccttca tcgctgcttg cggttgtttg aactcttccg ttttttctat
    11821 atcaaaaaga tgttctgcgg ccttttccgt gtcatttcgt acggttgttt tcccagtgga
    11881 tggattgact gctatgactt gtccttcaca aaaaaactgg tattcatatg ttgcattcgt
    11941 aggattctcc aaatcttttt caactgcaaa atgaatagca gatatgttat gttcttttgt
    12001 ttcgtttttt acgattgctg ctgctttttt caatgagatc cgatattcct ggtcactaat
    12061 atcatccatg tgaaaagcgg cattgagcag tcccgtcata ccggtaatcc ctattacgat
    12121 gagggcagca acaccaaaca tcattttttt cattcttcat tctcctgttt ctttttttta
    12181 aagaatatca agaaatgaac gaatgaaaaa tcgaatgaaa cgaaaaaaaa gtgacaattt
    12241 tgttatcttt attcgtgcag ttctaatggc aatccgtctg gatcaaagaa aaacgtcatt
    12301 ttttttcctg taaaggtatc ttctctaatc ggttctgatt cgatccctaa ggactgcaat
    12361 tctgcaattg tttcttcaat atcgtctact ttgaaagcaa gatgacgcaa gccacaagct
    12421 tctggatagt ttggtcgttg tggcgcatta gcaattccaa aaatctccaa ttcagcactt
    12481 cctagtttca gatctaattt atagtcatct cgttctttgc ggtaattttc tctgattact
    12541 tcaaatccta atttattaac ataaaaatca cgtgatttct gataatctga aacaatgatg
    12601 gctatatgat ggatcgttgt aaggttcata tgagcactcc tattcttcgt ttaagctcgg
    12661 atctatatta atctccagtt ccattgtaaa tgtgtcagat tgaaaaaaat agctgttttt
    12721 cctttttata agaaaaaagg caaaaaaaac agaaagtagg tcctccaaga cactcttcct
    12781 gttcccaata taataaatga aagtaagaaa ttatattttc aagaaaacaa acagaaaatt
    12841 atcataacac aaattattta taattgaaag actagttttt tttcaagaaa agcatacaat
    12901 agattgtgtt agtaaataca gaacacacta catttagtgt cttaaggagt cctcatacat
    12961 gaagtcatat tttcagtttt tagctcatca gctaaaaggc tggccgcaac aaaattatta
    13021 tcttttcttt ttcagtcttg gctgccaggt catgactctt gtcaatagtc ccatcacttg
    13081 gctgtccgtt attacattta tcggtaccac gcttggtgta ttgtgtattt tatccatcaa
    13141 tgcggcaaaa tcagtcaacg gtattttagg tattttgtct gcgatttgtt ttattatcgt
    13201 tgggttttca gcaaagaact atttaagtat cggtgaacag attgcttata tgatcacatt
    13261 ggatatcccc gtattgttaa gtaaagaatg gaatcataat atggcttcaa aaatccgaaa
    13321 attcactgga aaaagctggt ttatcgcaat catcagtact ttccttgtct atcttgtttc
    13381 aggattcctg attggtcgtt atacagatga tcctcggccg tgggtagatg ccattgcttt
    13441 ttctattagc ttgactgctg gtatcatcag tttcttgcgt tacaacaacc aatattactg
    13501 gtggttagct tcagggcttg ctcaaatggt cctttggtat atttcattta cgcatggatc
    13561 tgcaagtttg gcgatgttcg tgaacagctc tgtttacttg ctgaatgatg tccttgcatt
    13621 taccgtttca ccttggtata accaaaaaga acgtgaacgt atgcaaaaaa tggaagaaga
    13681 atactacaac gcacaacaac acgcataaaa aaactgagcg tgggacaaaa gtaaagaaca
    13741 cttttgtctc acgctctaaa cacgtataaa cggcggaatc agaagcaact ccttcggaaa
    13801 taagctgaaa ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg
    13861 agttaaacgc ttctgtccca gcctctattt tttatagtaa ttccttcaga tactttcttg
    13921 cctcatcatt gaaacgcagt gattcttcta acttctgata atattccaac gcttgtttct
    13981 gagcttcagt aaaacgataa tgttttcctt tccatttgtc gattgtctct tgcacatttc
    14041 cagattggat atctttcact actagttgcc atttttcttt tgagactgta cggtctttct
    14101 tatcagcaga ttgtatagct tctcgttctt tacgcaatac ttttaaaaaa ccatttctga
    14161 ctatccgagg aatgctgtcg aagaaccctt ctgtaaaacc atagcgacaa tattgcttcc
    14221 aaataaatag atagattttt ggttggatga atcgttggtt tttcgcaaaa tattccatct
    14281 gagcagtgac ttctggtgtt cgttgacgtt ttgtctttct caacacggaa ataaatgttt
    14341 caaaataagc attaggatgt actggcactt cttcatatac gatggattgc caatctttac
    14401 gtaaaaatgc gcgatagttg atcaagaatt cttctacatc ctttactaat tcttctgcaa
    14461 agtcgtcaaa tagttctttt tttatctgtc gcttttttga ctgcccattg atgtgttcac
    14521 ttattttctt gatttcattt tccaatgctt gataatccgc tatgtaaatc ggcatttcta
    14581 cttggcgaaa ttctgcgagc cgctgagcta attttatatc cggtaaatat ggctgtttca
    14641 tccgacgatt ttggtacaag acaaaacagt atttttgcca tagtccttca ggaaaatcga
    14701 tattcttctg cttaagccat aataattcgt ctaaggccag atcaactttt gtcattccct
    14761 gatggatcga agctgccact gtcggagaga catgcaggtg atcggcaaag tggttgatgc
    14821 ctagttttag gatctttccg gtttttggcg atttaacgat gtattgcact tttaattctc
    14881 taccacactc acaatacaat ttttgctggc ttcgttttgt tcgaaaaaac ggattgatct
    14941 tgaagtcaga aaacacccaa tctgttgcag ctaaataatg ttcttccata aaacgagagc
    15001 tgattagata tcggcggtgc ttatcgacta gttcccgctg ttttttcgtt aattttgcat
    15061 agatctccca acgttgactg cttgtgtatt gtttagaaat tttgatggga tagcttttgc
    15121 tgatttcttt tggaaaccat tcttcaaaga cggattgcca ttcttccacg gctgtttctt
    15181 tcctttctaa ttacaaaaag ctggctacta acataacgtt agcaaccagc cagtgtttct
    15241 tgctaaatta gtgagttgtt ccggcatttc cggaaatatc ttctttattt tctactgctg
    15301 cttcaactgc ataagtcaaa gaagaagcaa tgtcttctaa agacatagaa ggcgtaccca
    15361 ctggacgatc gatcacttga tcgggtgaga atggcacgtg gatgaaccca cctcgaattg
    15421 ccgggaattg tgtttcgatc aaatgaagca aacgatacat gatatcattg cagacaaatg
    15481 ttcctgctgt ataagagatg tacgctggta gaccatgatc ttgtacattt tttgtcattg
    15541 ctttgattgg caatgaggta aagtaagcgg ctggaccgtt ttcttctaaa gccgtatcga
    15601 atggctgatt tccttcatta tcagggattc ttgcttctgc tagattgatt gcgacacgtt
    15661 cgaacgagac tgctgaccgc ccacctgctt gtccgacaca gatcacgaca tctggttggt
    15721 gctgttggat ggcttctttg actacttgac tgcttttttc gaatacggtc ggtacttcca
    15781 ctttgatgat ttcagcaccg ctgatttcat ctggcatttt ttttactgct tcataggctg
    15841 gattcacttt gtccccacca aatggatcaa aacctgttac tagtactttc atctgttgtt
    15901 cctccgtccg attgatttaa catatggtta tcttttatca taccattttc cttgaacagc
    15961 gtaaataaag gaaacaatag tttaaataac ataacagatc aaacttaata tattcttata
    16021 aaaaaatagt gttccactac aatgttagaa gaggttgcga caattattct gtcacaaccc
    16081 ctctcttcta ttatttaaat agaatcatat aagcaatttg gaaaactagc ataaataacg
    16141 caataaacaa ctggtttttg atcactccgt atttgtcttt catctccagc atcgctacag
    16201 gcacgatatt gaagttagca gccatcggtg tcagcagggt cccacaaaaa ccgcaagtca
    16261 atgcaaccat tcctattaac gctggattcg ctccatgact aaatacgaat ggtgcaccga
    16321 tcccaaccgt catcacggtg atggccgcaa atgcattccc catgattacc gtaaatatca
    16381 ccatgccaag agcgtaaatg atgatgccga tgttcacatt tccttctgga acgatcgtac
    16441 ctactgcatt ggaaatcact gtcccaactc cagcgcttgt aaataccgca cctagagaag
    16501 ctaaaagcat tggcaacatg cttaacggcc ctactgtgcc cagcatatct gctgcatcat
    16561 ctaaaaatgt acttggtcga ttatctcgag aaaagaacat caagattagc atggctgcaa
    16621 aaacaccgac gcccacgccg actaaagcac ctaaattggt aaatagagca aacaagatcg
    16681 caaagacacc gatactcaaa gctggaataa aaattttcat tcctagtttg tctgacattt
    16741 tttccatata ttcttttgat ggaagccggc tttctccttt gctgactttc ttagcaattg
    16801 ctggtatggt catcgcaaag atcaagccac cgttcacgat tgccggaagc catcttcctc
    16861 ctgcaataac tacccctaag accgtccaga aaaaggctga cccataacga tgaggattgg
    16921 ttttatctgt taaatttctt actccagtgt aaatcaatac gagtcccatc acgatataaa
    16981 ggatctccag taatttatcg cctaataaaa tatcaggatt tgtaaaaaag tccatcttat
    17041 tgcccctttc ctggataata tttcttcgct aatttctttt ctttaagata gaagtagaca
    17101 cttgccacaa ctaaagccgt gatagccact ggaacttcca ctaaagcaag ctgtcccaat
    17161 gttacgtcat atcctagatc tttcagtgtt gattggacta gcaacgcccc tgctcctccg
    17221 atgaatagta cttggccaaa gaaccagcag acattttcca tagctgaagc catacctttt
    17281 agttcttctt catgcttagg atggacttct aacccttttg attcgatggt ccccaatgcc
    17341 atcggtaaaa tgattggacg aacaaatcca gcaactccac caaaactcac gttaaaagcc
    17401 gcaaagatca ttcgaaagat cccataaata tctacaatca taccagcaga tactttcttg
    17461 aatcgcttga tcaaggaagc cgctgattct ttcagaccat ttctttcaag cgttcctgtt
    17521 gccaacataa tgatgataaa aatcgccatc ccgcgattgt ttacaaaact tgtacctaaa
    17581 agttctaaca ttccttgaat gccaagaccg ccagtcaaag ctgtaacaac taaagcaacc
    17641 attacgatca atatcgagtc taatttaaat gcaaacccga gaataacaat caagacgcct
    17701 aaaaggctaa gataattttc catatatttt cctccataaa atgacaatat ttttttaatt
    17761 ataaagcaaa acacataaaa aatatagttg ttttctcacg aaatagacac tatttttaaa
    17821 tatttttcgt tattttttta tcacaaaaat tatcttactt attgtaaggt aaagcttttt
    17881 ttaatttatt gcccgataat atatagaaat aaggtctagt tactgttttt tttaaatgat
    17941 taataaataa caacttcttt ctatgaaatt gcaaagcatt catcttcttt tccgctaacg
    18001 atatatccgt cagtgcttgg tacactttac taaaaagtat gagattgccg atatctggat
    18061 aggtgtgcta tactacagaa aaagatatac aatctgccac cgggtaggat aaagaggatg
    18121 atcattccat taggtctttg aagggatgat tttcctcttt ttgtgtattt ttttatagtt
    18181 aaggaggaat gtaagtatgg catggatgga attaatcata gcaggaattt tggaagtatt
    18241 ctggtcaacg atgatgaaat ggagtgatgg tttttctaaa atcaattatt ctttttacac
    18301 agtgattggc atgattgcta gtttttactt tttgtcaaag gcaatcaaaa gtttgccgat
    18361 gagtctctct tatcctatct ggacagggat tggcgcagtt ggttcggtca taattggtgt
    18421 ggtcttgttt catgataagc tgaatctttc cacttggttc tttgtgggga tgctactcat
    18481 cagtatcatt ggcatcaaga ttactagcgg ccactagaca cttggaataa gtactgatca
    18541 gaaaaaataa gcctttttat ttaatattca atttttttat gaaaaaataa gaaataagtc
    18601 caatgaccta gcgacttctc cactcatcag gtgtatgctt gtactatcta tagaaaagga
    18661 gtgaatattt ttgaaaagtc tttcggtcca agaattatcc aagaactttg gtcacaaaca
    18721 agccctcagc gatgtcagtt ttagcttatc ccctggcaaa atcgttggat tagtaggtcc
    18781 taatggcgct ggaaaaacaa cgatcatgaa agctatttta ggactgatcc attactcaga
    18841 tggaacaatc tgtattggtg aaaatgagat ttctccctct agtcataaag ggttggaaca
    18901 agtaggagca ttgatcgaat acccgggtat ctatccattc ttaacaggct atgatcatct
    18961 gaagttattc tctgaaacca acgatgtatc tgctatcgac actatcgtga atcagctcaa
    19021 gatggaaaag tacattcaca aaaaagcgaa atcctactcg ttgggaatga aacaaaaatt
    19081 gggaattgct cttgccttac tgaaccatcc gtctatcgtt attttagatg agccgatgaa
    19141 cggtttggat ccacaagcaa caagagatgt gcgaaaaatc attaccgact tggctactca
    19201 gggcacctct ttcttgatct ccagtcactt actcagcgag cttgaaaaaa tggtcgatga
    19261 gctgatcctg atcaatcaag gaaagatcat caaacaatgt acaatggctg aattgaacca
    19321 aacagcgcaa gatttcatcg ttatctctac aacaaatgat ctagctgctc gaacgatctt
    19381 gacagaagct ggatatactt tggaagatcc tgataaaatc aagcttttaa aagaaaacga
    19441 agaattatta ggaaccgtga tccagctatt gtctgcacaa aatatccatg tgacagacgt
    19501 ccagcatctg acgaatgatt tggaatcttc tctattggaa attctggatt cagtaaaggg
    19561 ggaagaagaa aaatgacatt gcttgtaaaa caagaattat ttaaattgat caagaaaaag
    19621 tcaactgctg ttttatctgt tctattagtt gttttgctca taggaacagc acttctagcc
    19681 aaaaaataca cgacgatcat tgatccagtt gaaatgactg ctcagctttt tagtgccaca
    19741 tcttggattg tctttatcat gattgcagct gcaagcacga tcatttcgat ggaagcacaa
    19801 tatggtacat tgaaaaatct cctttatcga aagtattctc gaggagaaat attagtaagc
    19861 aaatggatca cattagttat ttattctgtt tatttatacc ttttagctat tattgtcact
    19921 gtgttgatga aactgattct tttcccttcg atttccttca cggagaaggt ttctactggt
    19981 caaacactga tccaaagctt gttcacttat actttgggta gttatatcgg tttatggctg
    20041 attttaagtt tagtgttgat gattgcttgc tttatcaata gttccggcgc atccatctca
    20101 gcaggaatcg tcttttattt tgcttcgtca atcatatctg gtatccttat tgcactcatc
    20161 caaaaatggg agtggatcaa atggaatccg atcagtatgt tgaatctgca aaaccaaatt
    20221 ggaaacgaag agatcatgaa gcaattgact catctttcta ctaatcaaat gctattcggt
    20281 aatttagctt acatcgtttt gttcttagca ttaggatatc tcgtatttaa gcgaaaaaat
    20341 gtatgatgac tcatcaaaaa agaggctgtg aaagagacgt tcagccttat tgccgattgg
    20401 ctgtctctta aacaccgttt attctgaaaa aggagctgtg acaacatttg tgtcacagct
    20461 cctttcctag tatgtttttg aataaacgac aggctcacaa cctctcttta tacttctttt
    20521 atacttctat acgtgaagca tcccagtggc aaataaaacc attgcaatca ctccgaccat
    20581 cgtcacacct ataagtaaaa tcttatctaa gtggatatgt tgtacaggct cgttttgctc
    20641 cttacgtgct ttgaggtaaa aataaatgcc tggcaagaaa agaacaagaa caagcattac
    20701 ttcattaaag gctacgacta gcatagccca tacttgaaag gcacttgcta aaagccctac
    20761 taaaaattgg acccattctt tccgctgata agaaagtttc atttggtaca atcctaagaa
    20821 aagccacgtg aagaaaatag ctgctgtacc aagtgtgtaa gcaaagttat aagcactgtc
    20881 agtgaataat aatgaaagta aaaagacatt cgtacataac gtcgtcaata cgatagcata
    20941 agttggtgcc ccatttttgt tgagttttcc ccatgcttta ggcaaaagtc cgtcttcagc
    21001 catgtttccc attgtttcaa tcggtaagat cgtccatgag agccaaacac caactaaaga
    21061 aatgatcaaa ccgccgttga tcacgactgc tccccattta ccaaccatca tttcaaacac
    21121 atagcccata gcaggctgcg ccttgatcgt ttgcagctga ttcatcgtca ttgtcccata
    21181 tggaagcatg gaaaccaaga cgtaaataat aatcaagccg aatatcccta gaatcgttgc
    21241 tttcccaaca tctgattgtt tttttgctcg tgaacctacg acagaggctc cttcaatacc
    21301 aacaaatacc caaagcatca ccatgatgca actcaatact tgactggaaa acgggatcgg
    21361 ctgtccattc gcattcaata taatgtcgct agaaaagtta tcaatgaatt gttggatcga
    21421 aaacgtgctg atagctacta caataaataa aaataatggc actaatttac agaatgtgac
    21481 gatagcattg acgaaactag cattttcgac tccccgattc actagccatg catatcccca
    21541 taaaaagact gtactcatca cgatcgatgc cagattttgc ccaccttcaa atactgggaa
    21601 gaaatatcct aatgcgctca tcaacaatgt tgcaaaagct acgttgccta accagcatgt
    21661 gagccagtaa ccccaaccgc tgataaaacc agcgaaacgg ccaaaacctt cttctgcgta
    21721 actaaagatc ccgcctttta aatctggacg ttttttattg atattattga tcgacaagga
    21781 gagcatcaac attgctgttc ctacgagtac ccaactgaaa atagctgggc cgccagccga
    21841 tccggagatg tccgtcataa taccaaatac gccacctcca atcgctgaac caattactaa
    21901 ggcagcaagt ggaattaaac caattccttt tttctgttgc tctgtatcca tgtaagcatc
    21961 ctccaaaata aaaccgcttt tatcaaaaag tataacaaac cttttttatt tttacttaat
    22021 taataaaaac tttaatagaa atataattct accggctttt ttctcattat acaagcaaag
    22081 cgcctagtcc ctttccaaat tacaccacca aaaaacttaa aaaagatgct atactaaaag
    22141 gaaagaattg gaggatgatc catgaacatt ttatatatat cgatttcagg aaatacgcgt
    22201 gcctttgcca aacatctagc agaatatgct gaaaaaatgc atgcagaaga tcctgtcaat
    22261 cctgaagtta ctttaaaaga aatccatgaa aatagtgatt ttacgaaaga aacagaacca
    22321 ttttttactt tcgttcctac ttatttagac ggcggaaatg gtttagataa cggtgataca
    22381 gaaatcttga ccgaaacgat gcgtgaatat ctggaacatg aagacaatca taaactttgt
    22441 cttggtgtag tcggtagcgg aaataaaaac ttcaataatc agtattgtct aacagccaaa
    22501 caatatgcac aaacatttgg ctttcctttc ttggcagatt atgaattacg gggaacacca
    22561 tctgatgtga cacgaattta tcagatttta gcagaaaaca ataaataata aaaaagaaga
    22621 agctgaaaaa tagatttcag tttcttcttt cgtttctatt gtttctatca tattaagctt
    22681 tgacatccat cacaggtgct tttgcttttg ctttacctgt tttttccaag acaaagtttt
    22741 ttacacgatc catattggtt accaagacga tcatggatgt ttctttgcct gctgctttga
    22801 tcgcttctaa gtcagcttct gctacaagcg tatcaggtgt cacttgctgc ccttctgtta
    22861 ctttcacatc aaatggcgta ccgcctaagt caactgtgtt gattcccata tgaagcaaga
    22921 tttctaaacc atttggcgtt gtgatcccaa tagcgtgttt cgttgggaag acagagctga
    22981 ctaccccagt aactggagaa tagatatgtc cgttttctgg ttctacaaag tagccttcac
    23041 ccatcatctt ttgtgcaaaa actggatcac ttgctttatc taaagaaaca actgttccgt
    23101 cagcaactga tgagaggata gtcacacttt cagctgaagt ttgaggtact actttttcag
    23161 gcacttcatt tactgtggct gtttcagtcg ctaattcttc tttttctaaa cggtctttag
    23221 gaataccgaa gaagaatgta gcaacgaagc caccagcata agctgccaat aatccaagga
    23281 tgtagcctaa ccatttaccg tcagagatca atgggatcaa agcggctcct gaaggtccaa
    23341 tagcgatagc cccgacattt ccgatcattc cgatcactgc cccgccgata cctccaccga
    23401 tacaagcagt aataaatggg cgtcctagag gtaatgttac tccgtaaatc aatggttcgc
    23461 cgattcctag gatcccgact ggtaaagctc ctttgatcat ttctgttaat tctttatctt
    23521 ttttgcagcg aatccataat gccaatgctg cacccacttg tcctgcacca gccatcgcaa
    23581 gaattggaag caatagcgta cgaccagttt catcaatcat ttgcacatgg attggagtca
    23641 aaatttgatg cagtccgaac ataaccatcg gcaagaataa tgtgcctaga acgaagccgg
    23701 caaatgctcc accaacgcca agtacccagt tgatcccacc gaccatgcca tcagaaatga
    23761 aacctgctaa aggcatgatg aagaaaattt caatcagacc gatggcaatc aatgaaagag
    23821 ttggtgtaac gatgatatct accgcatcag gtactacttt atgcagtttt ttctcaacga
    23881 ttgacaatag ccaaacagcg aagatgacac ctaggatccc accttgtcca gctgcaagag
    23941 cttcaccagt aaataagttt ttcagtggtg cttccggatt catccctgtc agcatcacaa
    24001 cggccccgat aactccacca agagttggtg ttgcaccaaa aacttgtgca gcattgatac
    24061 ctgtatagat aactaggtag ctaaacatcc cgtttttcaa gatgttcatc acatcgatat
    24121 attgttgcca tgttgctgca tcaagtgttc cggctgtgac taagtttgct aaaactgcgg
    24181 caatccctgc cacgatccca gtaccgacaa atgcaggaat cattggcaca aagatattag
    24241 aaatgtcttt taataccgat ttgattttag atggtttttg tttcgatttt tgtgccgctt
    24301 tcatttcttg tgcccgttcg tttacacggt cttttccaga tgctgatgaa tttgctgtag
    24361 ctgtacttac agaagaaagt ttttctccta atttcacgcc tgccaaatca accatttgct
    24421 gtgctacttt gttcactttc ccaggtccga tgatgacttg aagctgttca tcttctacta
    24481 caccaagcac tcctggaatc gcttttaatt cagagacatt tacaagatca tcattgatga
    24541 tcttcatacg cacacgagtc atgcagtgga caatgctttc tacattgccc atgccgcctg
    24601 cccctttata aatttgtttt gccagttctt ccaaagtcag ttcgtttttt gccatggtct
    24661 tttccccctc ataaggtccc ttttacaaat ccgtttgctt cagctaattt tgcttgagct
    24721 tcctctttat cactatttgt caaaatcatg acgatagcca gcttaacatt ttgatctgct
    24781 tcttcaaagt acttttcagc tgtttcgtaa tcagcttctg tcgcttgcat gatgattcgt
    24841 tttgagcgtt cgattagttt ttcatttgtt ggtttgacat cgaccatcaa gttattgaat
    24901 actttaccta taccaatcat actgatagta gaaatcatat tcaagataag tttttgtgct
    24961 gttcctgact tcaatcgagt agagcctgtc aaaaattctg gacctgcatc gacttcgatt
    25021 gggaaatccg cgtgtttact gatttcggct tgtttattgc aagaaatcgt tcctgtgaca
    25081 gcaccgatcg attttgcgta atctaatcca ccgatcacat atggtgtacg accgctagct
    25141 gcgataccaa taactatatc attttttgtc aaattcagct tgattagatc ttcttgccct
    25201 agctcataag aatcttcggc cccttcgaca gctacagtca ttgcttcttc tccaccagca
    25261 attagaccta tgaccatttc cggttctaca ccgaatgtcg gtacgcattc agcagcatct
    25321 aacacaccta gtcttccact tgttccggct cccatataaa tcagacgtcc acctttttta
    25381 aaggactcaa tcgtgttagc aatcactggt tcgatacttg tcagttcttt ttcaaccgca
    25441 gcggccactt tctgatcttc tttgttcatt agttgaacgg cttgagaaat actcatctca
    25501 tctaatccaa aagtttcttg gtttctgcgt tccgttgtta ggttctctaa attgattttg
    25561 ctcattttta tcttccttct tttcttataa attgatagtt cataccagct ttgatttggt
    25621 tgatcaatgg tagctcttct ttgataactt tagctactac attcactttt tcatccgctg
    25681 gcaaatcata tttggttaat tggatctcac ccatatagcg caaatacttt tcgttatcta
    25741 aagtaataga ccctttcata cgcgtagctg tatttcttgc tgggataggc ggaatctctc
    25801 gaaaacgtgc atctacgctt cgtatgacat ctcttgcatc gtcttgccga ttcgtatgct
    25861 tccctaatat atattcgtaa aattcttcat ctacaggttc cgtatggagc aagactgtct
    25921 gttctttttg gaaagaagca aattgctcct gaacgttttc tgacagacct gcatctccga
    25981 tgtaaacaat atccgtgtta cttgctaata gatctagagc gcctgcaaga ggatggatcc
    26041 ctcgatgttc ttccaaagtt ggcaatcctt gatatagtgg gcctctcaac tctgtatctc
    26101 ctggtacaaa accttggaca aggagacctt gaattttgag ccattgattt tttttctgat
    26161 accattcttt gtccagccct gtttcgggac gtggataata attatgccaa gcttcaatct
    26221 gtgagaaatc agcttctgct tctttcaatt catcgatatc tttaggcgtg atcgtgctag
    26281 cattcaaact gattttcaat tgatgtgacc agtcggcaat ctgctgattg gaaatatgat
    26341 aatccattct taaacctgtt acaccaattg ctttcaaagg cgttagatct tctaatgaaa
    26401 aacccgctcg ttccaatgcc tctcctgaaa tatcgaccat caattctagt ttattctttt
    26461 tcgcttcgct tcctagttcg atcaatcgct tttgatatgc cgaaacatca tcttctggta
    26521 tatgcatgga agtgaaaata ccgacaaagc cattggatgc catttggcgg atatactgtt
    26581 tcttctcttc tgacaaagaa tcgttcataa atattgaaaa gccaaacata ttatccctct
    26641 ttttctgtat ccgtcttcat ttctatgact agagtatata tctaaagaaa caaaatttca
    26701 atacttttat taaaataatt aaatttcatt tctaaaggtt gagtttatat tatcaaaaga
    26761 attgtcataa cctaaaaaag gcactgctaa gcaaaagcag tgccttgaaa tattttattt
    26821 aaataacaca aaaacataat tactcataag aaaccaattc tgtattatct accatgaatg
    26881 taaagaaccc ctcattaggc atcggatgaa aataagcatt gatcactctt atcaaggcat
    26941 tatggcaaac taacagatag acattttctt cgtcttcgat gcattctttc aataaaggaa
    27001 cgatccgtgc atacacatct aagactgact ccccatttgg gaatcgtaca gcgaacgcta
    27061 aacgtgcttt ttgaaagttc tcatctttgc ttggcagtcc atcataatcc ccaaaatcca
    27121 tttctaccaa tcgttcatca acggtcagcg gcaagctgag acgatcagca actgcttgtg
    27181 ctgtatctct tgctcgttga agaggggaat ggatgatttt cgtgattgga acaggcaaat
    27241 ctactacctt ttctgctagt ttctgtgcct gcatctgtcc tttttcagtc agcggcacat
    27301 ctgcccgtcc gcaaactaat ccttgtgcgt tccaagttgt ttctccgtgt ctcgttacat
    27361 aaagcatgtg attctctcct tcgttggcaa agttcccctt aaccatacct tgttgttctt
    27421 gagattacaa gggttagatt ctctcaagag aaataatctc agtagatact ttatccagga
    27481 aggtttgatc atgttccact agtaacatgg caggtttcac gttcaagatc agttgttcta
    27541 attgttcttg attgaagaca tccaaataat tcaatggttc atcccatgta tatagttcag
    27601 ctggctgtga taaagattta gccaattcca cttttttccg ttggcccata ctcatctgct
    27661 cgatcttgtt atgaaaaaca tctctttcca tcccaagctt tcggaggttg ttcaaaaatg
    27721 cttggtagtc tacttggttt ttctctgcaa attccgccaa cgttcctcga ttgtcttcat
    27781 aattttggct tgcataacta atgctcagat gttttggctg gtatttttct cctataacct
    27841 tgccgttgaa tgcccccaga agataatgga taatggatga ctttcctgca ccgttaggac
    27901 ctgaaatcgc cacccgctga tgaggctcga ttgtaaaatg aattggctcg aataacagat
    27961 tttcataccc taattgaaga tcttctacgc ttaaaagtcg cttatggtga gacgcttggc
    28021 tattcatcgt caaagaatcg atatattcga tatcttttaa tagtttttct ttctcgctga
    28081 tctgggtctc catccgattc acgattgctt tggatcgttt catcgtccgt gcagcatcag
    28141 cacccactgc tcctttattc actcgtctag attcagtatc gatgaatccg acttgtttct
    28201 ttgttttatc tccttctcgg gaacgagacc attcggcttt ttcagctgct gttttcttta
    28261 gcctactgac ttcttttttc aatttttcat tttgagccat ttcaaattca tcacgaagtt
    28321 ttttctgttc ttcatagata gagaaattcc cttgataaag ttccagttga cttttttcga
    28381 ttgctaaaac atggtccact acttcatcga taaatccccg gtcatggctg accacgatga
    28441 agccttgttt tttctttttc aaataagccg ctacttgttt tctaccagag atatccaaat
    28501 gattcgttgg ttcatcgatt aacgggaaat gagtgtcatc cacaaataaa agtgccagta
    28561 ggacttttgt cttctctccc cccgatagtg tgctgaattc tctccataag atttcaggat
    28621 ctgtttgcat caattggagc tctctttcga tttcccatat ctcaaaatcc gtaatatcat
    28681 ttaacacgta ataggttaaa cgttctttat cttttgtctg ttgcgggaaa taggcaaatt
    28741 cttgctgatg gattacttgc ccttgataag gtagtttgtt ttgtagaata ttcagtaaag
    28801 ttgtctttcc tcgaccgttt cgtccgataa gtcctagttt ccattgtgtg tcaaaattta
    28861 gatttgcttg ttcaaataat aatgtgcctt ggctgtcgta gccgaatgtc agatttttta
    28921 tttcgatttt agacattttc catcacctcg taaaaaaaga ccagtcctat tttcagaact
    28981 ggctaaagag gatgcaaggg ttggatacac acaaaaagac ccatacatcg aaaaaaccaa
    29041 gccaatcccg aaaatctgca cactgcttcc ttgtctccac aaggtacagt ctgaatgcag
    29101 ctttcatcaa tcgacttaat ttttcaatgc acggatccct cactttgtcc tatatttgaa
    29161 attacgatag cataaagaaa atgattttgt caactacttc gggaggatgg tgaaaaatct
    29221 gctaagtgtc tgtcctaaga tttttgtttt ttctaatgtt tgcctgtgtt ccattgcttc
    29281 ttctaaacct attggaccca aatgaatact taagacaatt gggagaaaat cagaaagtcc
    29341 ttctagctct tggtctctac ttccgcaaat agcgattatt ggttttcgat atttttttgc
    29401 aagcactgct acaccgtatg gaacttttcc gtggatcgtt tgctgatcga tccgcccttc
    29461 tcctgtaatg atgacatctg cttgttcgat ctttttttcc aatccagtga tttggctgac
    29521 taaatcgaaa ccagaaacca tcttcgctcc caacaaaaaa agggctccac caataccgcc
    29581 tgctgctcca cttcctggaa tatcatctaa atccacctcc cagaaatctt ttatttgctg
    29641 agcaatcttt cctgcttgtt tatctaagaa agctagcgtc gtatctattc ctcctttttg
    29701 tcttccaaat tgccaagcag ctccttgttg acctgtatat ggattggtaa catctgcagc
    29761 gataatcaat tttactttag aaacaagaac gtttcttcga tcaaaatgaa gttttttagt
    29821 agataataaa ggatttcctt ctgtgtaccc ttctaaagaa gcacccaagg attggagtaa
    29881 tcctagacca ccatcgctac acccgcttcc tcctaaagtg acaataattt gttctacttc
    29941 ttgaagcagt gcatctttaa taagttctcc taaggcataa ctggaagcaa gtcggatagt
    30001 ttgatccgtt ggtttatcaa gtagatctaa ccccaatgct tgtgcagatt cgatgactgc
    30061 ggtgtttttt ccttgccaag ttgtcaataa atagctgatt tttcgctgac ggaataagag
    30121 atccatccca tcaatggtac gccatgttcc cctgagcgcg taatagattg cttctgcagt
    30181 attttctccg ccatctgcaa tcggcacatt gatttttctt cctttacgat cttcccagcc
    30241 atttagaact gcctgattta gttcaaatga agaagcactt cctttaaatg aatcaattgc
    30301 cgccaaaata tccatctgta tccctcactt tcttcttaag taagacactt tttttcattt
    30361 ttttcaaaca aaacaatgct attttcttcc atttttctat atactaaaag ggaactcatt
    30421 gaataaagga gagaaaaaac atgaaaatcg caatagctgg ggccggagca atgggcagcc
    30481 gaatcggatt gatgctacat caaagcggaa atgaggtcct cttgatcgat cgttggcctg
    30541 ctcacattga agccattcgt acaaatgggt tgattgctga ctttaacggt aaagaagtgg
    30601 tcgcaaaact gccaatctat tcaccagaag aaatcatcga aagcaacgaa cacgtggact
    30661 tgatcgtagc attaacaaaa gccaatcaat tagatgatat gttttgttcg atccaatcca
    30721 ttattactga caatacttat gttttgtgtt tactaaatgg attaggtcat gaagatgtac
    30781 tggaaaaata tgtgccaaag aaaaatatct tatttgggat cacgatgtgg acagctggtc
    30841 tagctggtcc cggaaaagtc acattgttag gtgatggaga aatcgaacta gagaacttgg
    30901 aaccagaagg cgaagcattt acaaaaaaag ttgtagaagt ctttcaagaa gcaaatttaa
    30961 atccgatcta tagccataac gttcgttatt ccatttggcg aaaagcttgt gtaaatggaa
    31021 cattgaatgg tttatgcacg attttggatt gtaatattgc tgaactaggc gcgcaaaaag
    31081 cggcagagag catggttcga acaatcgtat ctgaatttgc ttctatcgca gcaaaagaag
    31141 gaatcatact agatcaagaa gaagtgtacc aacatattgc ttctacttat gatcctgaca
    31201 acatcgggtt gcattaccca tctatgtacc aagacctgat caaaaaccat cgtttgactg
    31261 aaatcgacta catcaatggt gccatttggc gaaaaggaca aaaatatgat attgctacac
    31321 catattgtgc ctttttgacc caattagtcc atgcaaaaga aggaatcctt ggcgcagaat
    31381 aaaaggctct ctgatgagaa tcagctgaat cagcagctgg ttctcttttt ttaagcccaa
    31441 taaaagatca aaaagaaaac acaactctca tgatgccata agaattgtgc ttgtttgttt
    31501 cagtacataa tctcttcaaa atgtaggttt tttatttgtt ttcaacagag gagaggtcat
    31561 attcgtattg ctcataaata gtggaatcgt tagtgataaa tcgttttgcc caattttctg
    31621 catcataaaa ttccaatagc tctgatagga ttggcttaaa tggtgtatgc agaaattccg
    31681 gtaattcatc taaatcacgt tctcgaagca aaaaaatatt ttcaggacga taaaaatgat
    31741 aatgagcaat cgcttgatta tccgtcacta gtttcttttg aaaatacatg gattcaaatg
    31801 tccgcaaagt cactccttgc tgaccctccc gcaacagttc cagaatcccg cgcgattccc
    31861 ctgttttttt caggtactct tcataagtaa gatatccagg ttgttcattc cctcgatgtg
    31921 gaagaatgaa atagttggtc gtaacatctc tttttataaa ttcctgctta tagctttctg
    31981 ctcgttcttt tctcccatta ttcgttgcac caaaaaatag atccgtcttt ggttcgctag
    32041 aagaaaaatt catatgtttc gaataaaatg aactattatg tttcagccca agttcttttg
    32101 cttccaaaaa atcaaaatga taaatctcat cgattgccgg ttcatcttgt gcctgcttca
    32161 gcatcgcctc gtgttctgct ttgaagtgat tccaaaaaaa taacacaatt tttgcattgg
    32221 taaatgggcg cacgcgtcga gccatctcca tatcaaatcc ataatctaaa aaaacgatca
    32281 gctgataatt tgccaactgt tgtctagctg atttaatgaa ttccgactgt agtaaatctt
    32341 ttccggacca aacatctaaa gagcggatgg aaggcaaaaa ataaagtgat ttattttttg
    32401 caactagcag tacgtcattt ttgttcatct tttccgcctc actttctctg tcactttttc
    32461 ctatgatagc ctgtttaaat agtaaaaagc cagtaaaacg tttcctatat ttgtatgaaa
    32521 atttaacatt tgtatgaaaa tatgatgaaa taaatcattc ttctattaaa attcgcctaa
    32581 aagttttctg aatagttgta attgtctgaa aatttgttat cattagtcat tgttaaatat
    32641 tgctatttat tcttaatata aattttgatt gtgaatttaa aagaaagagg tcatttatgg
    32701 aagataaaaa attgaaaaaa caacttagct ccagacatat caccatgtta gctttaggtg
    32761 gagcaatcgg tgcaggtcta tttaaaggaa gtggcgaagc gattgggatc gccggccctt
    32821 ctgtattgat tgcttttttg attggtgggc tgattttata tatcgtgatg aaaggtctgg
    32881 gaaaaatcgt tttaagcggt ggcgacacgc atcacggatt atctggtttg atacgccctt
    32941 atctaggtgc tcattctgct gattttactg attgggtcta ctggtctatg tggattatca
    33001 atatcatcgc tgaagctgtt gcagctgctt cctttttgca gttgtggttc ccgcacattc
    33061 cagcctgggt atttgttttt atgttggctg ttttaactac gatcatcaat ctttattcgg
    33121 tacggttatt cgcagaaaca gaatattggc tggcttttgc taaaatcagt gtcattatct
    33181 tactgatcat ttttgctact tatcttgtcg gtcagcaaat gttgggcaca ggcgttttcc
    33241 ctacccttca gcaattgact gaccatggtg ggtttactcc tcatggtatg aagggaatca
    33301 tcagttcttt gcttgtagtt atctattctt acggcggttc tgaactgatt gctatcacgg
    33361 taagcgaagc agatgatcct aaacgtgcga ttcctaaagc aatcaaaggt gtcatgggaa
    33421 gaatcatttc cttttacatc attcctttgt ttttgctttt gattcttttt ccttggaata
    33481 ctttagcagg cacgaatgtc agtccttttg tgatggtatt tgaaaaaatg aatatcccat
    33541 ttgcagcgga tatcgtcaat tttgtgattg tccttgcttt gttctcatct atcaattcgg
    33601 gtgtgtatgc atcttcaaga attttgttct tccgtttgaa ggatcgaaaa ggttcctcta
    33661 gaaaactagc tgttttaaac aagcatcaag taccgcaacg tgctgtttta ttttgtacca
    33721 gtgttcttta tcttggtgta gctctttctt attttgtcgg tgacaaatta tttggctatc
    33781 tggcaggttc cctttcgtat acagtattat tgatctggat cattatcagt gcggcatcct
    33841 ttgtactggc actaagaaaa ggaacattat gggataaagg aatcagcttt tttgcattag
    33901 ctgtcttagg attgattttc cttggtatcc tgttcacgaa ctccattggg gtaactgtat
    33961 tgactggcct gctttacctg ttcatttatt tcagttatca aaaaaagaat gatgcgttcg
    34021 tattgacgaa tgaatgaaat cgatagaaaa ttttatttta tttatgtgga atagatggag
    34081 ctattgaaga aaggagttgt gacaaaagtc ttgttgcaac tcctttttcc gaataaacag
    34141 tctcatgacc tcttggtaaa cggtgttcaa aaaccctctg tgcaaaataa ttgattgttc
    34201 tccatgctca tgacatgata gaagaaagga atgaaaaaaa ggagtttgtt ttaaatgaaa
    34261 aagtattgga agtttttgtt gatgatcggt gtttcaacgg tagttatgtt tggtatgatg
    34321 tacttgaatg tctatgcgct cgatcatatc ttcttcagtc gtacacgagt attcatggcg
    34381 ttgatgatgg gtgcagtcat ggcagtcatc atgctgttgt tcatgtggaa aatgtatgaa
    34441 aacaaaaaga taaatgttat gatcttagcc gctagtcttc ttgtttttgc cggttccttg
    34501 tttatggtac gaagccaaac tactgtcaac gacacagctt ggatgaaggc catgattcct
    34561 catcattcta tcgctatcct ggcaagtaaa cgagctgatt taaaagatcc tgaagtaaaa
    34621 aaattagcgg aagaaatcat tcaggcacaa gaagaagaga tcgacaaaat gaaaaaaatg
    34681 atcaaagaaa tggaatgacc attatccgtc caaataaaaa aagaggatgt tccagaagtt
    34741 atcagcttca agaaataaga agaagctact tctggaacgc cgtgaataag gggttgtgaa
    34801 aaagctgccc tgcatcaagt aataagaaca gccaaacaaa aatagcttct cctatttttc
    34861 gtttggttag gcttattacc gcagatgcaa gcttttgaac accgtttatt aagaggttgt
    34921 aaaatcagcg ttctgacctg agtattagag agacaaatgg aaaaatagtt cctcatattt
    34981 tgccattttt tgagctaata ccgagggtca gctgattgaa caccgtttat cgagaggttg
    35041 tgaaaaagtc gcttagtttc gcgtattaag aaaaattttg tgaaatggct ttccacattt
    35101 ttgtataaat ttggcttaat accgagaaac tggcttttga ataccgttta ttcgtaaaag
    35161 ggattgtgac aaaagtcttg tcacaatccc tttttatgtt tttattgttc taattgcgct
    35221 gtcttgctta ctgcttcttg cggtttcaca aatttttttg agattcccca acctgtgaag
    35281 gcactgacca tcgaaaacac aggagaaagc aaactgaaaa atacgaatgg caagtaagtg
    35341 agtgtaggaa taccaaatgt acttgctacg aaacttccgg caattcccca aggcactaag
    35401 tagttgatta ctgttccacc atcttctagc gttctaccta atacagttgg atcaaatcct
    35461 gctttttcat aagtttcttt aaatgcatta ccaggcagaa taacagatag gaattgttca
    35521 ccaataaaaa tatttactcc gatacttgtc atcaatgttg taaaaatcaa atttggtgtg
    35581 ttcgtcatct ttcttgatac tcgttccatc acggttgaga tcaagccaaa ttcgatcaac
    35641 aatccaccta atgacaaagt tagaataatc aatgacacag taggcatcat actttcgatt
    35701 cctccgcggc taagcagtga atcgatttgt tggtttccag tatttgaaac aaaccctgat
    35761 tcgatgaccc cagccaactt cgttaaggaa gtttgtgggt tttgaataaa aatcattcct
    35821 actgctacag cgatattcaa caaaatcgtt aaaattgccg gcaccttttt ccatgcacac
    35881 agtaacatta aaaataaagg aatcagtgac cagattgaaa tagtaaagtt tgcttctaga
    35941 acatcagtca cttcacgaat agatgaaaga cttgcggctt tacttgtgtg tcctaaaatc
    36001 atgaataaaa agaaagaaac aacaaatgcc gggacagttg accacatcat atgcttgatg
    36061 tgtttgaaca aatcggcatc aacaatagct gctgctagat ttgttgattc ggataatgga
    36121 gacatcttat ctccaaaaac ggcacctgaa acaatagctc caacaaccag cgctggattt
    36181 aagcctagtg ttgtcccaat accgaaaaat gcaatcccaa tcgttgacat aacagtaaag
    36241 gcactcccta cagcgctacc tacgattgca cacacaacaa atacagaagg gacaaaccac
    36301 tggacactga tcaatttgaa cccaatgacc attagagttg gaatgatccc tgcttgtatc
    36361 catacagcaa tcaatgaacc gactaaaata aaaataaaga ttgggatgat tcctggtttg
    36421 atgccattga tgattccttc gtgcagccaa tctgtcgggt atctttttat cactgcatac
    36481 aacatgacca ttccgatcgc tgctaagatc gtgatattag gtgagacctt taatccgaca
    36541 acgccaatcg caatgcctaa aacaataacc attaatacaa gtgttgcttc taaaaaactt
    36601 ggtgttcctt tttttcccat gataatctct ccttttttag ttgttcttat gttctaaaaa
    36661 agttaagata tcggattact ccgccgcaat tcatccgcga ttcctccttt ataaaaataa
    36721 aaagacctgt tttaaactaa ggacgaatga ctccgcggta ccaccttaat taaaaacaga
    36781 tctgtttttc actttcaaac ttttattcaa atgtatggac tttccatgta attcgtcaat
    36841 taggcttgat cggttcacag cgaccaccga ctttctgaac aaaacaccta accgctactg
    36901 cgtgaaaagt tgacttgtac gaagtttacc ttccataaga tcatttgtca atgaaaaaga
    36961 aaatattttt tcatttttct gaaaattatt tttataactt tcacacacaa gtttattttt
    37021 tactagaaag tagcgccctc ttgttttttt cttgctacta tttcttgatg ttcttgcttg
    37081 attctttcta atagctttgg ctctttcaac agatcaagag ctgtattggc gagtagttct
    37141 gctgcaatcg caatagaagc aaggcctttg tcacttttag cagcagcttt gaattcttct
    37201 gtgtgtccgg caatatatgt ctcagagatt gctaccgtag gctggattgt tggtatgact
    37261 tggctgacat ttcctacatc agaagaaccg agacttgttc tttgttccgt ttctatttct
    37321 tcatctggaa cacctgcttc ttttgcatgc tggaagaata agtcatcaaa agaaggagta
    37381 acgatgacat catcaactgc attttggaac aatccaaact caaaagtcgt gcccgtactt
    37441 atcgcagcac ctcgtacgat attttccact ttttcatata ctttatctaa tgtttgccga
    37501 tttcctgcac gtaaatagaa acgtccagca gcgtaatctg gaatgacgtt ggcagctact
    37561 cctccgtctg taatgatccc atggatattg acatcttttg gcaattgcaa gcgtagagcg
    37621 ttgattccat taaacacttg gatcaatgct tccaaagcat ttactccttt ttcaggtgct
    37681 gctgctgcat gggaagcgac accgtaaaat ttgatgtcga ctggatcatt cgctaaagat
    37741 tctgtcgttt tcccataacg aaaagctgga tggacgcata acgctacatc gacatcctca
    37801 aaaaaacctt ctcgaacaaa gctgccttta gctgatccgt tctcgccccc ttcttcccct
    37861 ggggtgccat atacacggat ttctccacca gtttcatcaa tgaattgctt cactatgctg
    37921 gcggctaata cggagtaagt accaaacaaa ttatgcccgc atgcatgacc aatacctggt
    37981 aaagcatcga attctgccaa aaaggcaatt gtgggaccgg gtttattgga aatataacgt
    38041 gcatcaaagg ctgttcggtg tccagctact tctttttcta cccaaaacct ttctttttct
    38101 aattgtttaa tcaacgctgc tgaggaataa aactcatagt tacttacttc aggatgttcg
    38161 tggatatcta gagcaagtgc ttgatattct ggtaaacgat attggattag atccttcaat
    38221 tggtttgttg agattgttgt tgtcataaaa aattcctcct atgctagtca tttttcttat
    38281 tttctcccga atgtttccca tgcaggcacg cttgatcctt ttgatgtttt ctcgattact
    38341 ttgactgtgt cttctgtttg ataagcgtct actatttttt gatacgtttt attgttttca
    38401 tcttcttttc ttgcaacgat gatattcaca taaggacgtg catggtcatc cactggttct
    38461 aagaagatgg catcagaagc aggattaaat ccagcatcta cagctacacc gctattgatc
    38521 actgaaatgt ctacatctga caaagcacgt gctgtttggg aagcatctaa ttcagaaatg
    38581 tctagatttt ttctattctc ggtaatatca gaaacagtgg gcgcttgtcc ttttgcctta
    38641 tccactttga tcaatccagc agtttgcaat aacagaagag ctctgccgcc atttgtaaca
    38701 tcattaggga ttgctacttt tgctccgtct ttgatatcag ctacatcctt caaagtgtta
    38761 gaataaattc ccagcggtgc attgacagta tttccgatcg atactaaatc agttccgtgt
    38821 tctttattgt aattgtctaa aaagaattga tgttggaaag aattcaaatc aatcgatcca
    38881 tctgctaaag ccacatttgg ttgattgtaa tctgtaaatt tcacgtattc caaattaatg
    38941 ttctcctttt tcaaacggtc tttcacgttg tcccatacat ctgtatcttc tccaataatc
    39001 cctagtttta cgatagtttc ttttttgtca gttgtatctg cttttccttg gctacaccct
    39061 gccaaccaaa taattgctac aaatgtaatg actacaaaac gaataatttt tttcattttt
    39121 tctcctccac tttcaatgtg taattttttt aatcagttga ttactgataa attgacttaa
    39181 aaaaactaag attagaatca ataatgtagc cacaatcgtt acatctgttt ggaatcgatt
    39241 ataccctctc gatatagcaa gattccctaa tccgcctgca cctactgctc cagccatggt
    39301 agtcagtccg atcacgttga tgatagtcaa cgccgagacc cgaatgatac caggcaaacc
    39361 ttctaacaaa tacacacgta aaatgatacc gattggactg gttcccatcg cttctgccgc
    39421 ttcgatcacc ccaggatcaa cttctagcag tgcgttctcg atttgacgag caaaaaacgg
    39481 aacaactcca aaaatcaatg gcactaaagc tgctttcgca ccaatcgtcg ttccaactaa
    39541 gaaacgagta gtcaatgcta aaagagaaag caagataatg aaagggatgg aacgaatgat
    39601 attgatcagc ttatcaagta tttcaaatag cagacggtta gctagtaatc cattagggcg
    39661 tgtcactact aacgtcacac ctaagatgat tccaatcatc ccgccaatga atgctgtcca
    39721 aaaagacata tatagtgttt gcttcgtcgc ttcgacaaat tcatccggaa tcaaataaac
    39781 attgggcaaa tatgttttaa agaaatcagt cattttatct tcctccttcg atcactttga
    39841 tacgactatc taaatcgttt ttttgtaaaa tatttatttt tacaccagat ttgatcaaat
    39901 aatccaatgc ttttttccgc tgtttggttt ctccagctaa agtaacgatc aaactcccta
    39961 acggcgtttc ttgtaataac tctacattgc catataaaat attcgctgtt acttgatatt
    40021 tgctgtacag atgagcgatt agaggttcgt tcgtctgatt tccaatataa cttaattcca
    40081 ccagccattt attggcgatc tgatcggcaa aagcagaatg ggcaatgatc gtttctaatg
    40141 cttggtcaag atgagtagct gttcgaataa aatctttggt caattcttct tcaggattgc
    40201 tgaagatctg gatgctgcta cctttttcaa cgattcttcc atcttccata accgctacct
    40261 tgttgcagat ttctttgaca acttgcatct catgagtgat caggacgatt gttaaaccta
    40321 actggcgatt caattttttt aacaatgcaa ggatctgaag ggtcgttttc ggatcaagtg
    40381 cactggttgc ttcatcacat aataatacct taggttcatt cgccaaagct cgtgcgattg
    40441 ctactcgttg tttttgtccc cccgacagtt gtttaggata agcagatgct ttttcttcca
    40501 aaccgacaag ttccagtagt tcattcactt tttgacgacg ttcctgtttc gattttccag
    40561 aatactttaa agaaaaatca acgttgtcaa aaatagttcg gctttccatt agattgaaat
    40621 gctgaaagat cataccgatg gcctttcttt cttttcgcaa ttctttggga gagagctgac
    40681 tcagattcgt ctgattgaca atgacttctc ctgctgttgg tttctgcagc aaattcatca
    40741 cacgaactaa cgtacttttc cctgcacctg agtaaccgac gattccataa acatcgcctt
    40801 tttcaatcgt taaatctaca gaatctactg cctgtatctc tttttctttt tgtttgaaac
    40861 atacagaaac atctcgcaat tcaatcatta aaattcctcc ttatctaaaa aaagcgtcct
    40921 caagaaaatg aaaatgtcat tttcttgagg acgctttttt gcgtgttacc acctcatgtt
    40981 caagctgtgt tcacacacaa ctcctcttca agtacgatca tactctagca agatatcggt
    41041 cgcagccgtc atcgccttac atctatgctc gggatgaatt gctcgatggc cattttccaa
    41101 tagtcgttcc ttgcttcttc tcagctaccg aagctctctg tcaaaggttc ttctatcgta
    41161 cttaccattt caatgcaaat aatattcaaa aaaaaagtcc ttttactaac ataaactatg
    41221 tcagtaaaag gacgacgtat cgcggtacca ccttttttcg gaagtttcct tccctcaagc
    41281 ccaacatctc aaaaagagag attggcgttc gttttaacgg tcgaacagtt ccgaatttgc
    41341 ctacttatcg acaaattatt ctccaaggcc attttcagct tttcttactt gactcttctc
    41401 accagccaga gcctctctgc aaagtttcca aacttacttt ccttttcaac gaaatcgata
    41461 ttttgttgtt gggattaatc tacatgagga aaactgaaaa gtcaagtacg aaattcaaat
    41521 tattttttct atatttattt ttctgttttt ttatttaaca tttcaataac agttcgaaga
    41581 tcttttcctt ccgcaagaag tttcaatttt tccttttctt cgacggtata atttcggaca
    41641 aaactggaat caggtatcaa aacaacgcct aatcctgctc gtgaagcagc tgttgctcct
    41701 actaaagaat cttccactgc aaaggctgaa ctagcttcta atcctgttcg ttccaaagct
    41761 gtcagataag gaatcggtga aggcttgttc tccgacactt cgtctccgaa tgtaaacgtg
    41821 tccaagtaat cagctaattt aaagtgatcc aagatatctg ttgctctttt cgtaacagtg
    41881 gtcgtagcaa tgcctagttt catatgacgt tcttttaagt ctgccaatat ttcttttgca
    41941 tatggtttta agtggatggc tccgcttgtc agctgttgat aaaaatattc ttcacgcttc
    42001 gctcggactt cctgtacttt ttcagggcta cctgctgctt tcactaaaat atcaaaactt
    42061 tgtttccagt tttttccgcc ccaagcgtca acgatttctt ttgggatatg gatatcaaat
    42121 tgctgaaatc cccaaagcca gccatcacga tacgtttttt ctgtgtcaac taacaaacca
    42181 tctaaatcaa atattgcacc tttcatctat acattaatcc tttccaaaac aatacacata
    42241 gtttagcacg actggtccaa aaagaacaga agcaaagaac cagccttctc gtttataaga
    42301 gttcttggaa tcgacggata tagattttct tcacagctgt cacaagcgcc agataagcga
    42361 tgactgtagc aaataaccat aaccagtaat tgccaggaag tggcatcaag cctaattcag
    42421 caccaaaact tgtaaaagga aggacagaac cgacaataat tcctaatgta gtgataacaa
    42481 acatggcaaa tgttgcgttg ctttggataa atggtacttt cggtgtacgc agtgcatgga
    42541 gcactaaggt ttgtgtccat agtgattcga caaaccatcc tgcatggaat aatgcgatga
    42601 aaatcactcg ctgtgaacta tccaatgtat ggaaacttcc gcccactaca gcaggacaaa
    42661 taacaaaata catcaacaag taagtagtaa tatcaaatat cgaacttgtt ggaccaaagt
    42721 aaaccatgaa ttccccaata ctagatgcat tccatttttt tggctcgtcc aaatattctt
    42781 tatccatccg atcccatggc aaggaaatgc aggaaacatc atagatcaga ttcaaaaaca
    42841 aaagttgtaa aggcagcatt ggtaaaaatg gcaggaacgt acttgcaatc agcacggaaa
    42901 acatattgcc aaaattagaa cttgctgtag ccttgatata tttcatgata ttcccaaaag
    42961 tttctcgtcc agaaagaagg cctctttcca aaatcgtcaa atctttttct aaaaggatca
    43021 cgtctgcaga ttctttcgca atatccacag ctgtatctac agaaataccg atatcagcca
    43081 ctttcattgc aggagcgtca ttgataccat ctcctaaaaa tccgacagta tgaccatttt
    43141 tacgtaaagc tgtcgtcaaa cgtgcttttt gctgaggatt caattttacg aatacttcat
    43201 ggtcttcagc tacttgtgct aattcatgat cactcatttc cgagattttc tcaccggtaa
    43261 ccaattcatt gatctctaga cctacttgac ggcacactga acgtgtaact aattcgttgt
    43321 ccccagtcag aacttttaca gctacaccat gttctttcag agctttcaac gcttgtttcg
    43381 ttgtttcttt tggtggatca aggaaagcaa gataaccaat caaaaccatg tctgactcat
    43441 ctttgactga aaattctcca acgacgcttg gattggtctt ttgtgcgaca ccaatcactc
    43501 gtaagccatc ttcattaagt gactgtactt ttgcaagtac ggcttctttt cgttcttttg
    43561 ttaatggtgt aacagtaccg ccaagatcaa taaatttaga aatgttcagc atttcttcaa
    43621 tcgcgccttt tgtgatcatt tgtgttttac cagctggatc agcaaccaca acactcatac
    43681 gacgacgttc aaaatcaaaa ggaatttcat ccactttttg ataattgatc ttatctgtat
    43741 ctaaagtttc tgttgcttca tcaatgatag ccacatctaa caaatttttc agccctgttt
    43801 gatagtagct atttagatac gcatggcgca aaacacgatc atcttcattt ccttcacaat
    43861 ccatatgata ttcaagaatg attttatctt gtgtcaatgt ccccgtttta tccgtacata
    43921 acacatcgat tgcaccaaag ttctggatgg cattcaaatt tttgatcact gttccttttt
    43981 tggccatcac acttgctcct ttgaccaaat tcgtcgtaac gatcattgga agcatttcag
    44041 gtgttagacc aactgctaca gatagtccaa aaagaaaagc ttctagccaa tccccttttg
    44101 taagcccatt gatgacgata actgctggag ccatcaatga cataaatttg atcagtagca
    44161 tggatgtttt atggatgcct aattcaaagc ttgattgaat tggtttttca gatagcgttt
    44221 ctgctacatg accaaatagt gtttcatttc caacagaaac aatgattcct tccgcacttc
    44281 cactgatgac attacttccc ataaagacaa gattttcgta acttgtttcg ctttgctgat
    44341 cgtcttcaca tactttcgca tgcttttcta ctggatagct ttcccctgtc aatgctgctt
    44401 gggaaatgaa taaatccttt gcggacaata aacgcatatc cgctggtatc atatcccctg
    44461 ctgaaagccg aacaagatct ccacagacga tttcttccat aggaatctct gtgtactttc
    44521 cattacgttt tacagctgcc gttactttca caagtgattt cagtttttca gccgcttgat
    44581 tggaacgtac ggactgaatc aacgtcattg tcccgctgac gataaccata gtgaagataa
    44641 tggctacacc gaaaagatct ttatctccag gagctgctaa tacatattcc gtgatgaatg
    44701 aaataattcc taatgcgatc aacactaatg taaatggcgt gatgtatgct ttcaatattt
    44761 ctacaatgaa tggtgttttt ttgccatatg aaatcgcatt ttcaccgtaa ttttctcttg
    44821 aacgttcgat ttgttcttct gtcaatccat ttgctgatgc atggaatagt tcaaataatt
    44881 cttgtttcgt ttttccagca aaagctgcat agattttttg tgtatctttc tttttttcca
    44941 tctcaatctc tcctttgtgt ccaaaagaca gctgttctcg ctgcttttgg tctttagcta
    45001 ttcatcggat cgatagagaa aaaactgaaa ggggctgaga acagatagat aatagccctg
    45061 gcctttcctc tagatccttg tttttcgaat gactgtcatc catttgttct catctccttt
    45121 actaagtaat tttaattcat gacttccaat catttttcga atagttattt ttccaattag
    45181 accacctcct ttttattttt caccgatggg gatttgcggc aacaaaaaaa cctctcgcca
    45241 aatactcagc gaaaggtttg aaaaagcata ttaaaaaaag cttctcagat ctcatcgttg
    45301 agttttgaca ctgtacaacg taaaaagcag atacctgctt ttagctacct tatgaaaagc
    45361 cttatctcga caattcctgt tctacccatt ggcgtctctc gacgtttttg ggcagtagcc
    45421 tatgtttgta taggagcctc acctaacaaa tcttattcgg ttttccttcg ttaatataac
    45481 aactaaaaaa gaggatgtca aatcaatttt ccatgttttt catacttttt ttaaaataca
    45541 cacgttatat tcctgtctca cgcggtttta tttgtctcat tttccacctc ccgctataat
    45601 agaaatatag taggaaacga ggtgctgtta tggaaagaac acttgttatt atcaagccag
    45661 acggcgtgag acgccattta gtcggaagca tcatccaacg ttttgaagca aagggactgg
    45721 ccattgctga aatgaagttt gaaactatga ctcctgaatt agcaaaagaa cattatcagc
    45781 acttgactga gcgcagtttt tttgatgaac tgatcgatta catgacttcc ggtcctgtcg
    45841 tttatcttgt gctggtcggc gaggaagtga tcgatatcgt ccgtaagatg gttggagcaa
    45901 caaaagctgc cgatgctgtt ccaggtacga tccgaggaga ctacgcgctg ccggggactg
    45961 aaaacatcat tcacgcttct gattcccgtg atgctgcggt aaaagagatc gcccgctttt
    46021 tcccgccatt cgatataaac aaaccgtctg aaaaagcggc gaagtgatac aaattctaaa
    46081 ctgctggtct agttgctggg ttcagcaatg gccagcagtt ttttctctaa ggacctccgt
    46141 tgattctttc ctaacatata ttcgagcact gtgaagaatt cttggtagtc tttcgtcttt
    46201 tcttccccta aagcagcaga aatcaatctt tgataataat ctgccatcaa tgtttcatag
    46261 atcactgtac ttctttcttt atgtgataag ctccgtttca tatcttcatt cacactacgt
    46321 gcctttttca accgaccatt ttctatataa aacgaagtca ggttcattaa aaaagtaaag
    46381 agatactgct catgattgtt caactgtgct aatcgtcgca ttcttttttt gattttcaaa
    46441 taattgttct caatgaaccg atcactgaat atccaaggaa aatcagctag aatagatagt
    46501 tcaaattgac catagtctgg tatctgcatc aagtattctt caatgattcg gcattcataa
    46561 cgtaaaaatt caaattctgt ctcagatact tctgtttttt cgaccatgtg aagattcaaa
    46621 accaaataat acagatcttc tgttttctta aaatgcctac ggttattgct gatctcttta
    46681 taaggatcaa agctgtcttc ttgtacccga tctagcattc gtcttttttt ctttaacttt
    46741 attggttcat ccagctggtt tcgcatccat tcatattctg caagtgtcat gttcattcgc
    46801 tctaaaaatg atctcaatgt tacaaatgac atttttttca ctgaatttgt ctcaatcccg
    46861 actagagaag tcttaaaaca gattccttcc gctaattggg actgtgtcaa cttcttgttg
    46921 actcgaagtt tcttgatcaa ttcaccatca tacataatag ttctcctttt taatttaaat
    46981 ttttccacat tcaataaata gatacgttaa aaaggaaaaa tacacgaaaa aaataaaaaa
    47041 atgttttttt cataaaaaat accaaccttc aagcattaga atgttgtcta actactgaag
    47101 gttggtttga ttgtttattg attatttttt tgctgttcaa cgtctgttct tgttactgga
    47161 tataagttgg ttgttgtttt attaccattt tttgaaaaga cacttgtcga atgttcgcct
    47221 ttttgctttt cgattgcttc attacgttcc gcttcatttt tatagtcata ttttttcgga
    47281 tcaatcgtct caaatccgtt tggcacataa aaccgcaaga gattttcctg attcagctta
    47341 tctgaaagac ttaacgcagt cttgactttt tcctgatctt tggagatttc ctcatcgatt
    47401 cctgctgctt tcgtatcgat gatttctcct gtctgattat tgtaagcttt tcctcctagg
    47461 acggtgtatt tgggtgtcac aaagttccca tttcgaaaag caactacttg atcatgctga
    47521 gaagataata agtctgtacc aaaatgaaga taatctttat catcgattcc caatagatgt
    47581 agtaatgtcg gcaaaacatc gatttctcca ccgtattcat gattgactgt ccctttagta
    47641 taaccaggca tatggatcat caatggcact cgttgcatct gtgcgttgtc aaattcatcc
    47701 catgtatctg gatctttacc aagagcgctt gctaaatctt tattatctgt attcgagatc
    47761 ccaaaatgat ccccgtaaat cacaaagatt gaattttggt aaataccaga ttttttcaaa
    47821 tacgtaaaaa attgttccaa tgattgatcc agataatgtg ccgttcgaac ataattatct
    47881 actgtgctat tgccagtatt caaagatgga aagtcgaaat tcttgtcatc cgtataataa
    47941 ggcgtgtggt tggttacgga aagaaatttc gtgtaaaacg gctgttgtag atgctcaaga
    48001 tattgggcag attctctgaa taaatcttta tctaatatcc cataacctaa cgtttcgtcg
    48061 gattcatcaa aataagatcg atcaaagaaa ttgtcataac ctaagttttt atatacatga
    48121 tctctattcc aaaaactagc tacattccca tggaaaacag cgcttgtata gccttgcttt
    48181 tgtccaagga tcgctggtgc ggcttgaaag acattgtctg acccaagttc tgtgaataat
    48241 gagccttgag gtaaaccaaa tgtgccagtt tccaacatat tttcagcatc acttgtcttt
    48301 ccctgtccta cttcatgaaa gaaattgtca aagctgatcg ttgcttgatt ctggaaaata
    48361 ctatttaaaa acggtgtgac ttcttgtccg tctaccttca tattaatcaa aaactgctgg
    48421 aaactttcta aatggagaac gatcacattt ttccctttag cgatcccaaa tgtttcggga
    48481 tttggctctg cataatgttt ctttgtataa tctaaaactt catcaatccc attactgctt
    48541 gcatgcgcgc gaacactgct agtcattcct gttttgattc cgtcataaat agtatacgca
    48601 tcgattccta gatatttgac aatatatgaa cggtcaaatg ttcgctgcag caattgtgga
    48661 cggttggctt cgctcagcgc tagatttcct gaaaaaataa gccctgaaag acaggtaaca
    48721 gcgatagcca tcggtttgcc gacagggttg cttttgatag gtattttctt gaccttcaac
    48781 caaaccagta gcccaatgaa cacagcgata tccagccagt agatgacatc atggggcttc
    48841 atcaaagaaa aggagcttcc tgacaatcct tgcgacactt tcgaaaagcc taatacagat
    48901 ttgactgtaa tgaaatctgt gaattcccga taaaaaataa tattcaagta caacaaaagc
    48961 gtatttaaaa tatcaatgat caaaagaata gctaacgctg gctttggctt tttaatatac
    49021 aaagaaaggc caaaaaacaa taaggtagtc gcaattgggt tgatccacaa gataaagtac
    49081 tggatcgtac cttccacacc taatgaaaaa tctgcatagt aggcaatgat cgtcttcagc
    49141 cagaaaaaga aaacagctgt caaaacgatt gctaaacgat tttggcacaa ttttttaagt
    49201 tgtgtcacgt atatcacttc tctctattca cattttttct tattttgctc ctgaaaaatg
    49261 aaaatttcct aaaaaagttg ttatcttaag atttttttat tctttctaaa gattattccg
    49321 tccacttttc acagcataaa accgctgcga tgtaagcgat taaactaatg aagagataaa
    49381 agtcttgtgg tgaccgcttc actccacggt attcaaaagc cagtttctcg gtattcgtac
    49441 aaaaaaagag gctgtgacaa aattcttgtc gcagctcctt atttcttgat gcaggacagc
    49501 tttttcacaa cttcttcctt aaacggtgtt ctcctgccaa ctcctcggcc acaagtcaca
    49561 atatttataa aacatgagaa gctgtttttt gaaattgttc cttgtggctc agagttaaac
    49621 ggcaggctca agacctcttg atacacggtg ttcaatcagc tgaccctcgg tattagatta
    49681 tgtcaggacg ctaattttac aacctcttgg taaacggtgt tcaaaagctt gcatctgcgg
    49741 taataagccc aaccaaacga aaaatataag gagctatttt ttgaaattgc tccttgtggc
    49801 tcagagttaa acggcaggct caagacctct tgatacacgg tgttcaatca gctgaccttc
    49861 ggtattagct caaaaaacgg caaaatatga ggaactattt tgccgtttgt ttctctaata
    49921 ctcaggtcaa aacgctgatt tcacaacctc tgtttttcat tgtccatagg attgatattg
    49981 tccttgtgat gactcattcg taataattga ggcttgattt tcttcacttc ccgttatcgt
    50041 ttgtccactg ccagaatctg aaggacttgt tcctgtcgac tcgttttttt gagaagagac
    50101 agttgttttc ttgacttgtt catttgtctt tttccattcc gctaaacgat cggcgaccac
    50161 ttttttgtct actttttcag aataagcggt gatcactttt ccatttttca aacgggctac
    50221 tttgtcgcca acatgagtca aaagcaaaac ggtcaaatgc ttgtctttaa attgatattg
    50281 tctgagagaa atcgcactaa gtacgtcatc gatattaata aattgatttt cttcttttcc
    50341 ttttggcaaa taaatgtcca attcgccttt ttcgtaattg gcagttattt tatactccgc
    50401 ccaccaataa gttgagaatt cttttttgaa attatctact gattctttgc ttgctacgat
    50461 tttttctgtt tctttctgag caagatctgc tgtcattttt cctgaaaatg ctgcggataa
    50521 aataagcagt aagaaaaaac cgaataacca aaagagaaga aacggtcttt ttttcctcat
    50581 gctttcctcc actcctattt aattttgact attctattat atacaaaaaa tgaaatagaa
    50641 agacaaaaaa gttgaaaaag atcgtaaata attgaacttc tttttcacaa aatggtaaga
    50701 atggagaatt tcacgcattt gctctcaact attctttctt aagcctcaaa tccgttttta
    50761 tctgatacgt ctttgaacca atgacccgat tttttgattg ttctttttcc atcttgtgct
    50821 aagtctactg aaataaagcc atatcgattc ttatatgcat tggtccacga ccagttatcc
    50881 atacatgtcc acatatgata gcctaaacaa ttggcacctt cttgaatggc ttgatggaca
    50941 tatttcagat gagattggac aaattcgatc cgataatcat cgtggatcat gccatcttct
    51001 ttgataaatc gtgcttcgtt ttctacaccc ataccgtttt cagaaataaa gcagtcgata
    51061 tttccataat gatctcgtac attgatcaaa atatcataga ttccttgttc atagatctcc
    51121 catccgcgat aaggattcat tttacgacca ggcatttcat aattgtcgaa ataatcctca
    51181 ggcattggac cgtttttagt atcgattggt gtttcttttg cttttacccg gcgtggctgg
    51241 taataattga tacctaaaag atctactgta ttttctttga taaccgtcaa atcctctgca
    51301 tggatcacag gcatgagatc aagttctttt actatctcaa tcaattcact tggaaactcg
    51361 ccttttacag ctggatcaag gaatgaacga ttgaagaacg catctgctat ttgcgctgct
    51421 ttaacatctt cagggtttga ttcgtctctt ggatagcttg gtgtcagatt caagatgata
    51481 ccaataacac caccttgctc catttcatgg taagatttga tggctaacgc tgaagccaac
    51541 gcttcatgat agccaacttg gatcgctttt ttcatatctg actcttctgg ataatgccat
    51601 cgatataaat aacctgcttc gactggaacg attggttcat tatgagtaaa ccattttttt
    51661 actttcgaac caaacaattc aaaacaactt ttggcatatt tttcataggc ttcaaccgtt
    51721 tctcggttca accatccgcc tttttcttgc agatacatcg gcatatcgaa atgatacaga
    51781 ttcacaaagg gttcgatacc gttttcaatc aactcatcaa aataacgatg atagaaacga
    51841 acggcttctt cgttgattgt tccagattca tcaggtatca aacggctcca ttggatagat
    51901 gttcgaaatg aattatgccc agtctgtttc atcaactgta catcctcttg atacttcgta
    51961 taaacttgcg aggttttttc aggtcctact tgatcaaaga acttttgcgg ttcttttttg
    52021 taccaataat caaaaatgtt ctctcctttt ccatcgcctg aaatccttcc ttctgtttgt
    52081 gggccacttg ctgcagaacc ccaccaaaaa tttgctggaa attgatattt tttcatcaaa
    52141 gcacctcttt ttctttttta gttcgtttta gttgattcca tgtatgatat tttccatcac
    52201 aatcactttt tcattttctt cctcttcttt tttgattcgt tttaacagct gttctgctgc
    52261 tcgttccccg attttatctg ttggtggcgt gatcgtgatt ttcggaagga tactcagatc
    52321 gtttttatct aaataatcat agtgactgaa cgcaatatcc ttcccgattc tgacaccttc
    52381 ttgattgaaa cattcgatgg caccaatcga catattgtaa ttgctgacaa aaatagcagt
    52441 tgcccctttt tctaataatg cttttgcccc gtaatagccg ctttttctag aatagtctcc
    52501 tgtaaagacc tctaattgga tcgatggatc attttggacc gcttctttgg ctcctgctaa
    52561 acgttctctt gctacgtagt ctgtttgagt ggcagcaata aatccgattt ttttatgtcc
    52621 ttgttcacca tgatgagcga tcacttttgc tacactttct cgatcattca ctaatattgt
    52681 atcaatacct gctggtcctt ctggacaatt caatgcgata actggaatac tcatttttgt
    52741 gagcatttca aatccagacc actcttcttc ggataagaag acaatcagcc catcgatcac
    52801 atgcttcatc aggtattcaa ttttttgttc aattttttct ggctgatcgg caaacccgct
    52861 taataataag ctatacccat tttcttcagc tactctttcg atccctgaga caacttccga
    52921 cccaaaacgg ctggaaatcc cgtttatcaa aagtccaata gagaagcttc gattattctt
    52981 caacccttta gcaatgatgt tttctttata gtccaacgct gaaatcgctt ctgctatttt
    53041 tttcatgttc ttttccttca gttgctgacc attcaagtaa cgggaaactg ttcccactga
    53101 aacaccagcc atcttagcca catcacggat cgatgccata cattctcact cctgccagtt
    53161 acatttgatt tctctttctt gttgttcgat tatgatgacc gcattctttg catagtgttg
    53221 cttgtcatca atatccatat aactaaagtc ttcagtagag caacttcctc tcactattaa
    53281 ttatacttaa acaagtattt gaaccggttc atttttaata tagcattttt ttaaaagatt
    53341 gcaacacttt tttaaaacgc tttctgaaag tggcggattt tttgcctttt taaaatttta
    53401 ttctaaaatt tactctattt gtgggtgttt tgtgcgtttt tctcttccat ccgtttgaag
    53461 ttttacattc caatggtata atttctttat cctatcaaat gggggaagta ttttgaagaa
    53521 attaatcgta ctatttattt tgtctgcggg acttttgaca ttgactggct gtgatttgtt
    53581 tggcggctct gaccaatcct cggacgaaac aaccgattct tctgtcttaa aagcggaaaa
    53641 agcagatacc accaacagtg tatatacgct aaaagtacgt aaagatatgg atttatccgc
    53701 gggacagttg acatttacag ataaaaaaat ggaatggaca cgcacgtatc agacacaagg
    53761 aactgattct tctgaatcat ctgaagaaaa aacagtgctg acagatatca agatcactac
    53821 caaagatgac gaatatatta tttcaggaaa agaaaataaa aaagaaacaa cagtcatatt
    53881 tacaaaaatc ggtaattacc gtttgaagga tgaggatggc aacatctaca gtctatagtg
    53941 ccgtctgttg gatcttcttt tgtttctccc cttcttttct gctatagtaa agaagcaaga
    54001 tgattgtaaa ggagacgaaa tggatgatcg atagtcctga ttattgtaca tgtaataaca
    54061 acaaaaatat ccatacagaa tttaatgacc aaggaagctt gagcatatgc gacaactgtc
    54121 acaaactagt caaagattca tttaaaacat ttgaatctta tcctgttcaa aattatgtaa
    54181 aaagtagaag aagataaaca aatccaagca aaactcacta tggctgattt ttatgaactt
    54241 caaactcagc ttcttccttt gatcaagctt catcagtaaa acaaacagtg gatcatttca
    54301 gtttacaaat caaagagtaa agatttattt atttcaaata tttgaatata aaataaccaa
    54361 acgatagaaa ggcttattct acatcacgta gtaatttttc tttcccgtcg tttggttttt
    54421 tatttttagc ctaattcttg accttttgca tgctggttat ccgtaaaata ttttccagca
    54481 ggctttcctt ccaattcagc taatttttct tggatctgac ggatcacctt ttttgcatct
    54541 tctggatttt ctacaaaatc gaatttatcc ccatccactt gtattttagg acatacatca
    54601 aaatcttcat accattgatt atagcgggtg ttcaacgttt cataataggt atataacgtc
    54661 tcatcgcttt ctagctgttc atagtcacgc ccacgttttt tgatacgttc tagcatcgtg
    54721 tccaaagaaa ctttgatatg gaccatcaaa tcaggccgtt tttttggagc aacatcatct
    54781 aactcgttta gcatcgtatc taataagcta tcgtactgct gtacttcgat atccgttacc
    54841 cgacctaaat cagcgtttag atggaacaac aggctatctt catagatgga tcggtctagc
    54901 acattgtcat cgttcactaa agcatttttc attgctaaaa atcgcttgtt caaaaagaag
    54961 atttgcaata aaaaagcgta ctgctcagga tttgaataaa agagcggcaa tacttcgtta
    55021 tcttcgacat tttcataaaa tggtttagaa tcaatctctt ttgcaagcat atccgtcaaa
    55081 ctgctcttac ctgcaccaat cgttcctgaa atcaaaatca ctgacataca acccttcctc
    55141 ttctataagt actcgcctac gtaagtttca acaggcaatg tttcaaaatc atattcacgt
    55201 acagcttggt ctgattttaa atacgtatgg agactttgtg taatcatcaa gttcgtaggt
    55261 accgtctctt cttgtacaat gatcatcggt tttttcaaca tagttgccac acctaattcg
    55321 taagccgttc ctggatcgat tgtttgatgc tcaaagtcaa ggatagcaac aacaaattct
    55381 gcatttgtca gttcttccat atctttttcg tatacttcct gcgcccatcc agcgctgaat
    55441 agttcataat tgctttcttg gtgatgacgt ggagagtaga aacttgtgac tgttttgttt
    55501 tcctccaacg ctttttcgat acgacttact cgatcgattt gctcctctga aaaaaatggt
    55561 cctgctaaat atatttgact cattattttg cctccttcaa taataactga tttttaatag
    55621 atactgctcg taattcattg accagttcca atggattgtt ggaaaagatt acttgatcca
    55681 accatttttt atccataaaa tcctcttttg caaaagtttc taataattgt tgcaagccgc
    55741 tgtaataacc gccaatattc aatattccga ttggcttgtc gggcgtcaga ccgattgcta
    55801 tccaagaaag aagttgtgag aattcctcca atgtacctag acctccaggg aaaacgagga
    55861 cagcatctcc cttttcaaat aataatacct ttctttcatc gatcgtttct gtaggaataa
    55921 atgtagtaac atcttttcca ggcaattcag tttcaaaaag cccattcgga tagatacctg
    55981 tgacttttcc gttattttcc agtactgttt tactaatcac tcccataatc ccggagtatg
    56041 aaccaccgta aaccagttcg atttcttctt gtgccatgta ttttcctaac gtttgcgcaa
    56101 taaatttgta actttcttta ttaccaaaac gggaaccgca aaaaacagta agtttcataa
    56161 aaaaacactc cctaactcaa aagtctatct tcattctaca cgtgtttttt taaaataaaa
    56221 gactagattt tgtagttttt tagtggtata taggatagac gccactatat atagtattta
    56281 gaaaaaaatc atttttcagc cattttatag ataaaacaaa aataaataac gtgttttcat
    56341 cgatatgaaa tgacttactt atagaagata ctgggatttc gtcctatatg ccaataacgt
    56401 gtattatttt aaacaacaaa tacttgtttc ttttattaac gaaaaaatca ttttgttctc
    56461 gtgttatgtt tcactgataa atgatgtttc tctaaataaa aaagccgacg aactaaacga
    56521 tcaaaatttg atcatttttg ttcatcagct tctcctaaaa atctttttgt taacgataaa
    56581 tagctggatt tgtaaaaata tcacttgaat cgtcactgct ggaagaaaat tcagtgataa
    56641 ccgcacctgt tgcgcctgcc tggaactagt gtttgatatt gggctcgaac gtgtactgat
    56701 ctctagcatg aagaataatt tcttttttta ctgtataata actttctttc ctttttggaa
    56761 tagtacagga aagttttttt gtttcctttc cttcgacata aggtatacca gaccctttcg
    56821 acaacgaaag gttctcattt ttccttcatc gtcatttcaa ggagggtgcc gatgctctgg
    56881 acagtttcga tcgctcctaa accaaaatct gtatattcga ttctttctaa ctctgattct
    56941 ttcataccat tcctgtctca aggtacatct attgtacttt tttcttgtaa tccattctgc
    57001 ctctcctaac taattgtcaa atcatcccaa gatatgtctt cttcctcttt ttcttcttgg
    57061 atgatttctg cattcggatc tactggtttt ttcaataata aaatggttat tcctgtgaca
    57121 aaagaaccag ctaacaatgc accaatgaat gcccatggtc tggtcatcgt agcgactgca
    57181 aacattcccg atgccggaat acggctatct gcgccccaaa acatgcttaa tccgccacct
    57241 actgtcccac cgactcccgt tgctatgaca ttgcgtgcca agtcgttcaa tacgataggg
    57301 aaacatccct ctgtgatctg acagatcccc ataggaaaag cggtcttcaa tgtatcgatt
    57361 tcttgacgat tgagtatatt tttacgaatg attttcccta agaaataagc gatcgtcaag
    57421 ccgaatgggg ttaccatcga agctaaaatc aatacagtga ttggttcata gattccttct
    57481 gaaaatcgtg ccacaccccc ttatccagaa taaatggtaa tccagaaaca gccgtgtatc
    57541 tgcggtaata agcctaacca aacgaaaaat atgagaagct atttttgttt ggctgttctt
    57601 attacttgat gcagggcagc tttttcacaa cctctttttt tatttatgtt tcataatcaa
    57661 tatggtaagg atgcagctcc gtatggtaga ccgcctccga atattcaatc atttccccaa
    57721 tttgcgtaga cgatttccgt atccgtttga tgccgatctg tgcgtctgtt ttcagaattc
    57781 cttgttcttc ttctgttaaa aatactgccg agaaatcatc agaaaatgag tcaatagtat
    57841 atcctttttt cgtcagcaaa cgatacaaag attctttgcc aaattcttct ctgctgaatt
    57901 gcatcatttc ttgtggaaga taatgaacaa aataaatata aggctgattg ttcaaataat
    57961 ataagcgctt aaaacaaaca gcttgctcac cgaaaaagga aaacaaagga tcttccttct
    58021 ttatatggac caattgcaaa tccagcgttt ctttccggac ttcatatcgg gagttctcca
    58081 agatttgcgt aaagcttgcc gctttggata atcgattgta aggacgattg cttagaaccg
    58141 tcgtcccacg accacttttc tttgcgacat attcatctga tgccagcagt tcgattgcct
    58201 ttcggacagt gattttgctg acttgaaaca gttcttctaa ttcactttct gtcggcaaca
    58261 tcgaaccgac tggatatttt cctgagaaaa tatcttcttt aattttatct gcgacttcca
    58321 agtatagtac acgtgtcctt ttcataacgt caccctttgc tttactatta ctaaaagaat
    58381 agcacataaa aaataaaaaa agaacacaaa tcacatgtga gaagtgtgtt ctttttcatt
    58441 cagctgcttt aattacaagt ttacgccatt tgaggcaatt acttctttat accaatcaaa
    58501 agattttttc tttgatcgat tcagtgtccc atttccttca tcgtctagat ccacatagat
    58561 aaagccgtaa cgtttactca tttctcctgt tgatgcactg acaagatcga tacatcccca
    58621 aggcgtatag cccatcaaat ctacaccgtc tgctactgca ttagccatcg cttcgatatg
    58681 acgacgtaaa taatcgatcc gataatcatc aataatcgtg ccatcctctt ccatatgatc
    58741 aatggctcca agaccgtttt caacaatgaa taatggtttc tggtaacgat tgtataattc
    58801 attcaatgcg attctcagcc cttctggatc gatctgccag ccccattcac ttgcctcaag
    58861 aaacggattt tttactcctc ccagcaagtt cccttctgaa gttgctgctt gtggatcagt
    58921 ctcattgatt gccgtagaca tataataact aaatccgatg tagtccactg gatattcttt
    58981 tagcaactgg aagtcttttt ccgtttgctc taatttttcc ggatcgactc catatttttt
    59041 atgggtacgc gctgtgtatg cagggtattc tccacgtact tggacatccg tgcagaaaaa
    59101 attgaattct tggttttgga tcattgttgc tgcctgattg actggattgg catcgatgct
    59161 gtaagttgtt gcatagataa tcatgcagcc gatttggata tccgaacgca attcgtggcc
    59221 gatttttacg gctttgctac ttgcaacgaa ttgattatgc catgcttgga aaatattttg
    59281 gtactctcct gctccattgc tttttactaa tccttgactt aaagctggaa agtgaaaggc
    59341 cgaattgatt tcattgaaag tcatccaata tttgacttta ctgctgtatc tctctaatac
    59401 tgtctgagca aatcgttcat agaagtcgat cagttttcga tttttccagc caccgtattc
    59461 ttttgccaaa tgaagaggca tttcgtaatg agaaatcgtg atcacaggtt caatatcata
    59521 ttttaagcac tcatcaatca gctgatcata aaattctaat cccgcttcgt taggagtacc
    59581 ttcgtctcca tttggaaaaa ttcgtgtcca ggcaatcgaa aaacgataac atttgaatcc
    59641 catttccgca aacaaggcaa gatcttcttt gaaacgatcg taatgatcaa ttcctcgatg
    59701 attcgggtaa atatattttt cttgatcaat cgtccagtca aattcttcac tgccgataat
    59761 cgcaaagcgc tgcttacctc caggcatagc atctgcaacg gatagccctt ttccgtctcg
    59821 atcataagcc ccttctaatt gattggcagc agttgctcca ccccataaaa atttttctga
    59881 aaaacgtgat tgcatcctga tttcctcctt attttacaat tgccagaaca tcttcgtttg
    59941 caataatctc tttttggtct aattcaagta tatcggcaaa tgcatcagta ttcgtaatga
    60001 caactggagt gattacgcta tagccagctg ctctaattgc ttcgatgtca aaacgaatca
    60061 ataaatctcc tgctttgacg agatcccctt gtttgactaa gatctcaaag ccattcccat
    60121 ttaattctac tgtatccatc ccgatatgaa tcaaaatctc cgctccgtca gtcgttgtga
    60181 tccctacagc atgtccagtt ggaaaaatag tcgtgatctc tccgtctgca ggtgcaacta
    60241 gttctcctac ttctggatca atagcgatac cttttcccat cacgccagaa gaaaaaactt
    60301 ggtctggtac ttcactcaat ggcagtactt tacccgttaa aggacttttt aaggtatgcc
    60361 gtgctgaagt aatcggttct cctgcattcg catgtttgtt ttctaattga ttgtcttgtg
    60421 tttgttcgtc aaatcctaaa atcaatgtac ctacgaatgc aagaacaaaa gcaattcctg
    60481 tagctattac tgctactgtc acatttgact ctacaccatc caccgtatta atgaaagtcg
    60541 gaatcgtcaa taagctgacc aaactgctgg agaaagcttt tactccggaa aatccgataa
    60601 tagctccacc aatacctcca gaaatacaag cggcaatgaa tggtttcttc aaaggtaatg
    60661 tcacaccata cacagttggt tcagtgattc caaataacga agtcactgta gaagaaatcc
    60721 ctaatgctcg aagtttcgta tcttttgttc gcaatgctac agctaaagca gccccacctt
    60781 gtgccaagat ggctggaaga agcattggca tcaatacatc aaacccatat tgttcgatat
    60841 tcaaaaacat gatcggtacg aatccccaat gcatgccgaa catcacgaat acttgccata
    60901 aacttcccat gattagacct gctacgattg gactaaatcc ataaatcgag ttgaagagac
    60961 cgcctaaagc attaccggca accgtcccga ttggtcctaa agcaagaaat gttaatggaa
    61021 ccatcactac taaaacgaca agcggaacta aaatcatttg cagaaattgc ggaatcactt
    61081 tttttacgaa tggctctaat ttactttgaa cccatacggc tagaatgatt ggtatgacag
    61141 aagaagtata accagatggt gaaagaatca ctgggatccc aaagaaactg atagcttctc
    61201 ccgcaccagc aactgctgtg atagctggat acacaagtgc catagcaatt gctactgcta
    61261 aaaactggtt ggctttgaac tttttagctg ctgtaaaagc aagcatgaca ggtaagaagg
    61321 taaagacacc atctgctgca gcaaacaata tttgataagt accgctatca gctgtcagcc
    61381 agcccatcac cgttgccaat gataagaatc ctttcaatac cccggcggct gccatcgccc
    61441 ctagaaaagg tgtaaatata ctagagataa tatcgatcag acgattcaaa atatttttgg
    61501 actcttcttt tccatcctcc gaaactgcaa gaccttcctc atccacgatc gattgataaa
    61561 catctgctac attactgcca atcactactt gatactgacc gccactttgt acgacttgga
    61621 tcacgtccgg gtcttctttt aacttttgcg tatctgctaa agattcatct tttaatctga
    61681 atcgcaaccg cgtagcacaa tgtactaaac ttttgacatt cttttgtcct cctaccgctt
    61741 cccatacacg acgaccaact gcttgattat ccattgtttt ttccttcttt cttttttatt
    61801 taaaaaataa aaacccagat tgaaaaaaac agtcacaaac attcgtgaac ctattttttc
    61861 aatccaggtt ttgcctgcca tacagtaaca atccttatga ttggatgctt tttttctcac
    61921 ttactactct ttgaatatga atcgttaaat aaatctgctc tgcgatcccc atttcctgtt
    61981 tttgcgtttg tcgaagatac tcattgatcc gttcgacaca atgaaacgct tttggatact
    62041 ttccttgaac taatgcgtag agaaattcat cttgctcgtc agatccttcc cctttgagat
    62101 aacgctgggc aaaaaactgc agatgagtaa tgatacgctg ataattcaaa gattcttcat
    62161 cgaacacgat gccgaagaat ttactgatga tactcagtat atctcttacc attgtggtag
    62221 cggtcatcgt cacttgcatg tcttcgtttc cttgttggct attcacaaaa tgaaaggcaa
    62281 taaaaccggc ttcatcctca gaaagttcca cacccgtctt ttgtttcacg aacaaaagag
    62341 cctctttcgc tgcttgatat tctttcggat aaaatttttt tgtttcaaat aataatggat
    62401 taggcagttg gatattttct tttgctcgtg tgatcgcata atgaagatga tcggtcaatg
    62461 tcagataaat attaggcgaa aattcaactt ttagtttatc ttcagccagt tcgactactt
    62521 gtttgaccca ttcgatctcc tctgccggaa tatcagccat cagctgctgg aattggtttt
    62581 tagcaaaaga atctcttaaa acaaattctt tttggaccgc ttctggcgaa atctcgtccc
    62641 caatcttttt ttgaaaagct agtccttttc ccatacaaac gacttcttcc ccgaatccat
    62701 ttttcgaaat gacgacattg ttattcaaaa ttttatcaat tttcattttg cttcgccctc
    62761 tcaagaaaaa taaaaaaacc tagaattcgc ctactgtttc ttagctgaat tctggttttg
    62821 cctgccgtac agtaacaatc catttcttat tcaaaatcat cataccatcg aatttttatt
    62881 tatgcaagcc ttttcatata aaaaataaaa aaactggaac acaagtctat ctagaaaaca
    62941 accaaatcag agatgcacct ctttgcgttt ctcttttttt cagcaaattg gtttttcctt
    63001 atcgattcat atcctttggc tgtttttaat ctgtaacgac ttatgtccca gtatcctaaa
    63061 atgtttttgt ctctagattg aaagcagatc tcatatcatc tgtcgcatct tttatcgatg
    63121 taacactttc cagttctcct tgtacaacta gtcgcgtgac ggcgtccatg tcgccacaag
    63181 taattagtgt gacaatttct tttccctcga cttcattcag taattgggta tctgtaggag
    63241 caactttttc tttaaaaaat gttttgtatg tatacacatt ttctaaatct gtcaaataga
    63301 tcttggcacc catctctaaa ttttctagcg gtgtaaacag caattcaggg ttcgttgcac
    63361 gatggcttgc taaggcataa tttccttttc ccatttcttg atctggagat aatgttcctg
    63421 ctccgtaaag tagtgacgta ttatccaagc ctttgaaaac cggtaaattg attgaaactg
    63481 aagggactgc gatactagca atcactggta gatctgttcc tctcatttgc gacctcatga
    63541 ccccttctgt cgtcattggt tctaccgcat caaagtcaaa actgacatct ttatcgttat
    63601 tctttttcag atcttctttt gttacattcg ctatagcata tttatctcct gtctctctga
    63661 caaaataatc cttgatctgt tcattgaaaa tcaaagctag tcctactaat aacaagagga
    63721 acaagaggat attgactagc catctttttg cttttccttt ttttttcatt ttctctccct
    63781 ccagactcat tttactgttt ttcttttgct ctttccaaca gccgaatgac acatttctac
    63841 aactctgtgt atttttttcg tacacctgcg cttttttcta caggatattt caaattattt
    63901 ttgatcaatt tttcttcaat gatctcatct agatccaggt gaaggttgtc tgccatcatg
    63961 tatgaataga tcaatacatc tgccagttct tctttgattc gttctaattg tgtttctttt
    64021 acttcttccg gcgttttcca ttgaaaaagt tctaacaatt cagatgcttc caaagaaata
    64081 gagatagcca aatctttttc gttatgaaat tgtcgccaat tacgttcatc tctaaactgg
    64141 ttgacttttt ccatactatt catttgcttg ccttcttcca atcacttctt acttgattaa
    64201 tcataccatt tttttacata aaaaatagat gatgctttta aaaaaactcc tgttttcttt
    64261 tatttaaaat aaatgtcata gaaaatcaat aatttaggta gccaccatgt gtatgcagta
    64321 gcgtgtcttc ttcccttgag gctttttgtt tttcgatacg ttcttcttcc caaacagaca
    64381 acgctactag aatctctctt aatgattttc cttcttcggt gagcgagtac tctactttag
    64441 gcgggacttg gttataggct tttcgatgga tactttcatc ttgttctaac tctcttaact
    64501 gctgggtcag catttttttt gtgatcgtag ggatttgctt gcttctccac gcctaaaata
    64561 agcgatattg ctcttccctt tatctggtgt aagcaaagca gttagcattt tgacgatcgt
    64621 gggttccgct tttcacttct tatctactta gtatcatgaa gtatactttc gtactaatac
    64681 taagtagcgg aagtgtcaac tactttgttt aactacatag caaaagaaac agaagggtga
    64741 caacggtcat cacgcttctg tttcttttga atatgctgtg ttgttgtctc tatctccgtg
    64801 tagactttcc tcaaacttat cctttgacag taagtcagta ggctgatttg ctctttctag
    64861 atgccagata catttctaca aaaaaatagt gattctgttt tgaaaattcg atttttagtt
    64921 ctgcattttc gtaaacatcc aacatttttt tcgcactgta tagacctaac ccgccatttt
    64981 ttttagaggt ttttcctctt ttgaccatct ccgatagcgt caaattcgtt ggatttgcct
    65041 tgttcgctat actaaaacgt gatccctctt tttcttccag cagattgatc gtaatcggac
    65101 tctgatcggc tacacgatga tcgaatgcgt tagaaataaa aatagataaa cagcgaataa
    65161 aaacaaccag atcaatcggg attgttttca cttcgacagg aataactact tggatcggga
    65221 ttttctccga ttctgctttt tctagaaatt ttaaaaagac acccctgaca gctggggata
    65281 caatatttgt tagctgttgt atttgcggtt tttcaaaaat agctgcagaa tgatcttcta
    65341 atatttctaa aaattccaac gtttcttttt tattttcctg aagagtaatt tttaatgaaa
    65401 acagtagact tttataatca tgtttgaatt cctctagatg atggtaatat tcttcattta
    65461 tttgatacag ttgaagcgat tcctgatgtt gtctttcttt tacttggaaa ctgatcaaca
    65521 taatggaaaa aaacaaagaa aaaaaactga tgactatcga caaaagagat agaagcagat
    65581 aattagatga gcggaagtga acacttccca ataccaagta aatcacgccc cagcttaata
    65641 aaatacaaat acctccaaaa tagtgttcag ttggataagt aaaaagcaag ttgagaaatc
    65701 tcgtctgttt gtctatactt tttactaata gatagaaaat aaatgcgata agtagtgcaa
    65761 aaaaacttgc tgttccaaga tgtctctttc ctaaataatc catcagatca aaaaccagaa
    65821 aaaagctgag tccagtgata gcaaaaaaaa gattactgat caaacagctg ataaacaggt
    65881 ttttcgtagt aaaataaaaa agaaacatca ataataagcc aattaggtaa ggaaagctca
    65941 ctttagggat aggaagtaaa agtgtcacca ccatcaaagc tatacaacca aagctgtttt
    66001 ttactagcag ttgtttcgaa aagaataaat agatacctaa atctaaaatc aaagtaaagg
    66061 tcaaataaag tgtcactgtt gcgaccatct tattcctcca ttgttttgtt tcaaaatgta
    66121 cacatatttt tttaatagga gcctgcatat gaaaaagtat tttatcatag aagataacca
    66181 gtttcacagc gaatggatca tcagagaatt ggtcaatcat catatcgaga atatcgtgca
    66241 gctcacttct atctctcaaa tcaatcagtt gatccagttg ggcactattg ataatcacga
    66301 tgttttcttt atcgatatcg acttgaagca atcactcaca ggtattgatg tcgccgaaca
    66361 aatacgtaaa aaaaatgcac atagtaatat tgtttttttc accgcttata cgaattttgc
    66421 agtagagatc atcaatcgga aaatccttcc gattggatat atcagaaaag acaggaattt
    66481 atctgaacaa attcgtcaag tgctagaaca gatcaattgg aaagaacagc agatcgtaaa
    66541 tgtcgataaa atctttattg atcaaaaagg tggaagtc
//
LOCUS       DAXLPQ010000010        52450 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.010, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000010 DAXLPQ010000000
VERSION     DAXLPQ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.010"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            1..794
                     /locus_tag="ACF3UO_000847"
                     /pseudo
     CDS             1..794
                     /locus_tag="ACF3UO_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            934..1860
                     /gene="cysK"
                     /locus_tag="ACF3UO_000848"
     CDS             934..1860
                     /gene="cysK"
                     /locus_tag="ACF3UO_000848"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFD3656894.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2096..2542
                     /locus_tag="ACF3UO_000849"
     CDS             2096..2542
                     /locus_tag="ACF3UO_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3656895.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2814..4166
                     /locus_tag="ACF3UO_000850"
     CDS             2814..4166
                     /locus_tag="ACF3UO_000850"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFD3656896.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4337..4624
                     /locus_tag="ACF3UO_000851"
     CDS             4337..4624
                     /locus_tag="ACF3UO_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3656897.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4850..5293
                     /locus_tag="ACF3UO_000852"
     CDS             4850..5293
                     /locus_tag="ACF3UO_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFD3656898.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5299..6483)
                     /locus_tag="ACF3UO_000853"
     CDS             complement(5299..6483)
                     /locus_tag="ACF3UO_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFD3656899.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6751..7449
                     /locus_tag="ACF3UO_000854"
     CDS             6751..7449
                     /locus_tag="ACF3UO_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD3656900.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7456..8133
                     /gene="nth"
                     /locus_tag="ACF3UO_000855"
     CDS             7456..8133
                     /gene="nth"
                     /locus_tag="ACF3UO_000855"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFD3656901.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8259..8792)
                     /locus_tag="ACF3UO_000856"
     CDS             complement(8259..8792)
                     /locus_tag="ACF3UO_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656902.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9089..11470)
                     /locus_tag="ACF3UO_000857"
     CDS             complement(9089..11470)
                     /locus_tag="ACF3UO_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFD3656903.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11460..12107)
                     /gene="recU"
                     /locus_tag="ACF3UO_000858"
     CDS             complement(11460..12107)
                     /gene="recU"
                     /locus_tag="ACF3UO_000858"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFD3656904.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12171..12710
                     /locus_tag="ACF3UO_000859"
     CDS             12171..12710
                     /locus_tag="ACF3UO_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFD3656905.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12800..13219
                     /gene="gpsB"
                     /locus_tag="ACF3UO_000860"
     CDS             12800..13219
                     /gene="gpsB"
                     /locus_tag="ACF3UO_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFD3656906.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13241..13608
                     /gene="rnpB"
                     /locus_tag="ACF3UO_000861"
     ncRNA           13241..13608
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACF3UO_000861"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13817..14983
                     /locus_tag="ACF3UO_000862"
     CDS             13817..14983
                     /locus_tag="ACF3UO_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFD3656907.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15029..16525
                     /locus_tag="ACF3UO_000863"
     CDS             15029..16525
                     /locus_tag="ACF3UO_000863"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFD3656908.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYGIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16606..17289
                     /locus_tag="ACF3UO_000864"
     CDS             16606..17289
                     /locus_tag="ACF3UO_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3656909.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17934..19124
                     /locus_tag="ACF3UO_000865"
     CDS             17934..19124
                     /locus_tag="ACF3UO_000865"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFD3656910.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19226..20179
                     /locus_tag="ACF3UO_000866"
     CDS             19226..20179
                     /locus_tag="ACF3UO_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFD3656911.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20248..21597
                     /locus_tag="ACF3UO_000867"
     CDS             20248..21597
                     /locus_tag="ACF3UO_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3656912.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21780..22103)
                     /locus_tag="ACF3UO_000868"
     CDS             complement(21780..22103)
                     /locus_tag="ACF3UO_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656913.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22232..23395
                     /locus_tag="ACF3UO_000869"
     CDS             22232..23395
                     /locus_tag="ACF3UO_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3656914.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23465..24814
                     /locus_tag="ACF3UO_000870"
     CDS             23465..24814
                     /locus_tag="ACF3UO_000870"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3656915.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24859..25290)
                     /locus_tag="ACF3UO_000871"
     CDS             complement(24859..25290)
                     /locus_tag="ACF3UO_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3656916.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25678..28320
                     /gene="alaS"
                     /locus_tag="ACF3UO_000872"
     CDS             25678..28320
                     /gene="alaS"
                     /locus_tag="ACF3UO_000872"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFD3656917.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28520..29116
                     /locus_tag="ACF3UO_000873"
     CDS             28520..29116
                     /locus_tag="ACF3UO_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3656918.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29238..30386
                     /locus_tag="ACF3UO_000874"
     CDS             29238..30386
                     /locus_tag="ACF3UO_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3656919.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30424..30837)
                     /locus_tag="ACF3UO_000875"
     CDS             complement(30424..30837)
                     /locus_tag="ACF3UO_000875"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFD3656920.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30916..31347
                     /locus_tag="ACF3UO_000876"
     CDS             30916..31347
                     /locus_tag="ACF3UO_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFD3656921.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31446..31679)
                     /locus_tag="ACF3UO_000877"
     CDS             complement(31446..31679)
                     /locus_tag="ACF3UO_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3656922.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31862..33532
                     /locus_tag="ACF3UO_000878"
     CDS             31862..33532
                     /locus_tag="ACF3UO_000878"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFD3656923.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33679..34065
                     /locus_tag="ACF3UO_000879"
     CDS             33679..34065
                     /locus_tag="ACF3UO_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656924.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34052..34750
                     /locus_tag="ACF3UO_000880"
     CDS             34052..34750
                     /locus_tag="ACF3UO_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFD3656925.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34755..35219
                     /gene="lspA"
                     /locus_tag="ACF3UO_000881"
     CDS             34755..35219
                     /gene="lspA"
                     /locus_tag="ACF3UO_000881"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFD3656926.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35216..36127
                     /locus_tag="ACF3UO_000882"
     CDS             35216..36127
                     /locus_tag="ACF3UO_000882"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3656927.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36362..36901
                     /gene="pyrR"
                     /locus_tag="ACF3UO_000883"
     CDS             36362..36901
                     /gene="pyrR"
                     /locus_tag="ACF3UO_000883"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFD3656928.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36915..38198
                     /locus_tag="ACF3UO_000884"
     CDS             36915..38198
                     /locus_tag="ACF3UO_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFD3656929.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38211..39137
                     /locus_tag="ACF3UO_000885"
     CDS             38211..39137
                     /locus_tag="ACF3UO_000885"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFD3656930.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39156..40436
                     /locus_tag="ACF3UO_000886"
     CDS             39156..40436
                     /locus_tag="ACF3UO_000886"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFD3656931.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40441..41517
                     /locus_tag="ACF3UO_000887"
     CDS             40441..41517
                     /locus_tag="ACF3UO_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFD3656932.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41522..44707
                     /gene="carB"
                     /locus_tag="ACF3UO_000888"
     CDS             41522..44707
                     /gene="carB"
                     /locus_tag="ACF3UO_000888"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFD3656933.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44761..45537
                     /locus_tag="ACF3UO_000889"
     CDS             44761..45537
                     /locus_tag="ACF3UO_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFD3656934.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45534..46466
                     /locus_tag="ACF3UO_000890"
     CDS             45534..46466
                     /locus_tag="ACF3UO_000890"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFD3656935.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46463..47179
                     /gene="pyrF"
                     /locus_tag="ACF3UO_000891"
     CDS             46463..47179
                     /gene="pyrF"
                     /locus_tag="ACF3UO_000891"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFD3656936.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47186..47815
                     /gene="pyrE"
                     /locus_tag="ACF3UO_000892"
     CDS             47186..47815
                     /gene="pyrE"
                     /locus_tag="ACF3UO_000892"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFD3656937.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47803..48117
                     /locus_tag="ACF3UO_000893"
     CDS             47803..48117
                     /locus_tag="ACF3UO_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656938.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48155..48796
                     /locus_tag="ACF3UO_000894"
     CDS             48155..48796
                     /locus_tag="ACF3UO_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFD3656939.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48839..49531
                     /locus_tag="ACF3UO_000895"
     CDS             48839..49531
                     /locus_tag="ACF3UO_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFD3656940.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49528..50430
                     /locus_tag="ACF3UO_000896"
     CDS             49528..50430
                     /locus_tag="ACF3UO_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3656941.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50588..52294)
                     /gene="efbA"
                     /locus_tag="ACF3UO_000897"
     CDS             complement(50588..52294)
                     /gene="efbA"
                     /locus_tag="ACF3UO_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFD3656942.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17146 a         9140 c        11270 g        14894 t
ORIGIN      
        1 ggaacgagtc ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca
       61 gatgaacaag gatctcaaac agttgctgat cctcaagcgt ttatcgatca aatcggctgg
      121 tctgcgtcag aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg
      181 ttgttggaaa gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc
      241 ggtgtgaaag gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaacg
      301 gacaatgggt aacgatgaat gaaccattcc gaaaatattc ttcttattgg gaatccttcc
      361 aagaccatgc gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg
      421 gcgtgtggaa aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt
      481 atgctaccga tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa
      541 cccgttttga tacgccatca acaggttcgg ctaccacaag tacaacaaca acgactacta
      601 cgacgacttc aacgtcatca tcttcaacaa cagatgtaaa tacaaataat ggtcagacat
      661 atacagtcgt gtcaggtgat acgctatggg atattgcaca aaaatttggc atgtctgttg
      721 atgatctaat ggcgaaaaat ggcatgtcta tgtccagtta ttctttatta gttggtcaag
      781 aactaaacgt ttgatttaga taaaaaggca aagaaactac catatatggt atatctttgt
      841 cttttttttg ctagtcaaag acgaatcact cgccataaat gaacagattg tattatgata
      901 agtaagaaga gcaaagacaa ggaggaattg aagatgacag ctatctataa ctcagtcacc
      961 gaattgattg gcaaaacgcc aatcgtcaaa ttaaataaaa tcgtaccaga agattcagca
     1021 gatgtttttg taaagcttga gttttttaat ccaggaggaa gtgtaaaaga tcgtattgct
     1081 ttaagtatga tagaaaaagc agaacacgat ggtctactga aaccaggtga tactatcatt
     1141 gaacctactt ctggaaatac aggaatcgga ttgtcgatgg taggagttgc aaaaggatat
     1201 aaagtaatca tcgtgatgcc tgagacgatg agtatcgaaa gacgtttatt gatgaaaggg
     1261 tacggcgcag agttgatttt gactcctggt gcggatggta tttctggatc aatcagagaa
     1321 gcagaacgtt tggcaaaaga aaacggctac tttttaccat tacaatttga aaatgaagca
     1381 aatcctcttg tgcatgagaa gacgactggt cctgagatac atcaagcatt tggagtaaat
     1441 ggcttggacg cgtttgttgc aggtatcggt acaggaggaa cgatcactgg cgctggccga
     1501 gaattaaaac gtgtgtatcc gaaaatcgaa ttaatcgggg tagaaccagc agaatctgct
     1561 attttagaag ggaaagaagc gggacctcac aaaatccaag gaatcggtac aggttttgtt
     1621 cctaaaacac tggatacttc tgtgtatgat aaagtccttt ctattagtgg agacgaagcg
     1681 atggaaacag ctagagaagt tgggcgaaaa gaagggattt tagtaggcat ctcatctggc
     1741 gctgcaattg ctgccgcgct aaaagtcgca aaagaattag gaaaaggcaa gaaggtatta
     1801 gctgtggttc ccgacaatgg tgaacgttat ttatctacag ccctttacca agagatataa
     1861 ggcacttggt ttttctccag ataggtttat gtaaaaaact tttaaagatg aaaagaacac
     1921 acaaaaattt atgatgagaa aaattatttg aatagagacg taaaatagtg aacgcgactg
     1981 ttttacgtct tttttcatta aaatacaata aaattgaatt ttcttttcat gttaagtgga
     2041 ttttaaaatg taaaaatagt atgataagac gagaataaca acgtggggtg tttacatgga
     2101 aaataagtta gtcgaagagg ttatcgaaaa gttaaaaaaa gagaacattc gaatcacacc
     2161 tcaacggtac gcggttttag aatatttgat tgaacatcat tcccatccaa cggctgatga
     2221 gatttataaa gcacttgaac atcggtttcc aaatatgagt gttgcgactg tttacaataa
     2281 ccttcgctta tttacttcga ttggatttgt tcaagaaatg aagtacggcg atgcttctag
     2341 ccgatttgat ttcagttcaa agcgtcatta tcatgtaatt tgtgaaaact gcggtaagat
     2401 tgttgatttt cattacccag ggcttgaaga tatagaaatg gctgcgagca gactgactga
     2461 ttttgagatt aatgaacatc ggttggaatt gtatggactc tgtccggatt gtaaagagtc
     2521 agcaaaaaag gcgcaaatgt aaaaacagtt tctataagtg ttatacctaa aaaaagctag
     2581 ctgtgtaaaa aaacgctagc ttttttattt ttttgtcttt tattcacaat cttagatatc
     2641 aaagtgaata ttatcacaat aagaatcttg tagatattgg gttcttatgc ttgaaaagga
     2701 atgaaactac aaacaaacct ttgtgaattc acaagcatta aactgttgta tccgttttat
     2761 ttctgttata gtagttttgt cgaaggacaa aatgttaatc ggagggacca taaatgaaag
     2821 tagtagtaat tggctgtact catgcaggta ctgcagctgt aaaaagtatt ttaaaaaatc
     2881 atccagaagc agaagtgaca gtatatgaaa gaaatgacaa tatttctttc ttatcttgcg
     2941 gtatcgcact ttatgtcggc ggagtagtaa aggacccagc aggcttgttc tactcaaatc
     3001 ctgaagaatt atcttcatta ggagcaacag ttaaaatgga acacgatgta acagacgtcg
     3061 atacagaaaa taaaacagta acggcaaaag atctgaaaac aggagaaaca gaaacggttt
     3121 cttatgataa attagtgatg acaactggtt catggcctat tatcccaccg attagtggaa
     3181 tcgatgcgaa aaatgtactc ctatgcaaaa actacaatca agcaaatgaa attattgcac
     3241 aagcgaaaga agcaaaacgt gtagtaattg ttggtggtgg atatatcggt attgaattag
     3301 tagaagcttt tgtcgaatct ggaaaacaag tgacattgat tgatggatta gatcgcatct
     3361 tgaataaata tctagataaa ccattcacag atatcttaga aaaagaattg acagaccgcg
     3421 gtgttactct tgcgctaggc gaaaatgtta ctgaatttat cacagatgaa gaaggaaaag
     3481 tgaaacaagt agctacacca acagatacat ttgatacaga tatggtcatt ttatgtgtgg
     3541 gcttccgtcc aaatacaaaa ctgatcgaag gaaaagtaga tacactgcca aacggggcaa
     3601 tcaaagtgaa tgaatacatg cagacaagtg atccagacat ttttgcagct ggagactctg
     3661 cagtagtcaa ctacaatcca agtggcacgc aaaactatat tcctttggca acaaatgccg
     3721 ttcgtcaagg tttacttgtg ggaaataact tgacagatca taaaatggcg tatcgtggta
     3781 ctcaaggaac ttcaggactt tacctatttg gctggacgat cggttcgaca ggtgtgacca
     3841 aagaaagcgc aactttgaac gatctagaag tccaagcgac tgtatttgaa gataattatc
     3901 gtccagagtt catgccaact actgaaaaag taatgatgga gctagtctat gaaaaaggaa
     3961 cgaatcgtat cgtaggtgct cagttcatgt ccaaatacga cattacacaa tcagcaaata
     4021 ccatgtcttt agctgttcaa aataaaatga ctgtagaaga tctcgcactt tcagatttct
     4081 tcttccaacc acattttgac cgcccatgga attacttgaa cctacttgca caagaagcgc
     4141 taggcgaaat cgaaactgca caataaagaa aaagggttgt gacacaattt tgtcacgacc
     4201 ctctgtcttt ttttgtgaaa agtacaatta gttgtctttc ttcgaatttt ttgtcacaat
     4261 aagcagcaaa gataaagctg ttacataaaa gaacaagcag ctttatttga ttttgaaaag
     4321 aaaggtgaga aagaagatga ataaagaata ttttgtccaa caagatgcat ttttagaaga
     4381 ttataaaagt gcttcgaaga aattaacgat caatattgat gagttggcag atcaagtact
     4441 ctctcagttg aatgaaacgc aagaggaata ttacacgatg ccagcaaatg acgccaaaga
     4501 taatgtttct catcgttttc ctttcagtag acgcatctac tcagatgaaa atgacggcac
     4561 attgaataca gagtacacat atgaaggtca gccatatgtg ctagaaactg atgatgatct
     4621 ttaaagacag tttttgaaaa ggccgctcat ccttaagtga tgacaaaaaa tcatcacaat
     4681 taccgatgac tgtctcttta ctatctttta atcagaaaaa ggggttatga caagctttgt
     4741 caaccccttt ttttcttggt ttcagattgg gttttcctac aaaatatttt tatctttgtt
     4801 gaataggaaa caaaaaaaca atataatgaa agaaaaagaa ggtgtagaaa tggataaaag
     4861 acaactgcta atagaagaat atctggattt agctaatgag attattcatc gtaataaacc
     4921 agaaatggaa aaagaatttg caggatttac tctaaatgaa ctagaagtga ttgaacatat
     4981 cgggaaaatc cctgatccta acgtgacaaa attagcgaat gctagttaca tgactagagg
     5041 agccatcagt aagctaacaa aaaaactgat agctagaggg atcataaaca cttatcaaag
     5101 cgaagagaat aaaaaagaaa tctattttca attgacgcca atcggacaaa aaataaggaa
     5161 tagacacgag caactccatc aaaaatgggt acagcgagat gctactgtat ttgaaaatat
     5221 gtcaaaagaa gaatttgaca cagtatttcg ttttatcggt cgatacagag aatttatacg
     5281 aagtagcaaa tgaagctact attttttatt gtagtgataa taggcaaaaa tcataagcaa
     5341 aaatccgaat accgtcggaa gaaatggtgc tgcagcataa agctgtcctg cgattagcgg
     5401 gccgatgacg cgcgatagag attgtatact ttgggtaccg cccattacaa gaccttgctg
     5461 gttatctgag acagaattgg atagttggcc attgaataca ggagtaaaaa tagaatcacc
     5521 gaaaccataa cagataatcc caaataaaaa caaaatcggc agtagaagaa ttccagataa
     5581 tgtgatgaat agataggcga ggatttcact gaacatccct attcttgtga tctgctgttc
     5641 tgaaaatttt ttgagcaatc gaggcataat gaacaattgc gagacagtat ccaagattcc
     5701 aatcaaagag aagcttaaac caaccaaccc agccttccac tgaaaggcgt caatcgaaaa
     5761 ttgagaaaag atagattgaa gagagccagc tgccaaccaa acagcaaaac ctgctgtcaa
     5821 taaaggaata acggatgaaa tcttgaataa ttgttgtaat tggtgaaaag gtcttacatg
     5881 ggagaaactt aaatctactg aacgtttttt tattggaagg ctttctagca taaatgtgta
     5941 gccataaacg gcatttaaga aagtaaagag tgctccaata aatataggaa cagaattccc
     6001 caactcagct aatagacccc ctataatagg acccagcgtt gttcctatac cgactaaagc
     6061 acccatccat ccaaaaactt tggttctttc attaggttcc gtgatgtcgg caaagtaagc
     6121 atataaggtg gagatttctc ctgccgtcaa tccttcaatg atacgaccaa ggaacaacat
     6181 ccatatcgaa tttcctaaac caaaaagcaa atatccgata cttgatccta ataaactgat
     6241 aataaggatc ggatgacgcc caaaatgatc acttaagcta ccgagaatgg gggcagataa
     6301 gaaggcagct agagcataaa cagacatgag caaagtgata tagaaagctt gctgatgtat
     6361 ggagtgagaa taaggcagcg ttaaaaacgg aagtacagga ctgacgatag taaatcctaa
     6421 tccagtgaat aagacagaga cgtatccaaa aactttagaa tgtttatttg tgaaactgta
     6481 catgtaaaaa ctcctttatg caataatgtt aacttggaaa caaaaatagt gtatagtaat
     6541 tttgtttcct tgtcaacatt ctaaggaaca gcgaaatcta cttaatttat ttattccgaa
     6601 aagtgaagat acgcatcaaa aacatgaaca aacaaaaatc aagtagacga cattgtaaat
     6661 ctgaccgatc agtgaagtaa atagaaaaga aacctgttct tgcttcccat gtttttttta
     6721 cgtatactgt gattgagcgg aggagaaatc atgttgaatt tagaaaatta cttaagcgct
     6781 ggacaaacag tcatatctaa tcttttactt aaaaattatc ataggatcgg tctacaatct
     6841 gaagaatttt tatttgttct acagttgcat atggcacagc ttgaaggaga tactttccct
     6901 gatttgcaga tgattgctat ggatatggga atcaaacaag atcagatttt tcaaatactg
     6961 gatcgtctcg taacaaatgg atttatcaag atagaaacga cgattgtcaa cggtaaaaaa
     7021 gcagatcgat ataatcttta ccccatctat gatctattag gtgagtattt aaaaacacaa
     7081 gaaaaaaaat acgaagaaaa aacacaagaa aaagaaatcc agtcagtgta tcaattattt
     7141 gaacaagaat ttggacgccc gctttcttcg atcgagttcc agcggatcgg acaatggcta
     7201 gaagaagacc attatcagcc ggaaattttg aagctagcac tgcgggaagc cgtattaaat
     7261 caggcttata gttttaatta cgttgaccgc attttgctat cgtgggaaag aaaaaatcta
     7321 cgtacaaaac aacaagtgga agaagaccaa aaacgaagaa aacagcagct tcttcaaaga
     7381 gaagtagaac agtcagctca acaagaagaa ttgccgaaag tctcactgaa aaattggttg
     7441 gaggagtagc ggaatatgtt aagcaaacaa aaaacaatgg aagctctaga aacgatgtat
     7501 ggaatgtttc ccgaagcaca tggagaactc aagcacaata atccatttga gttattgatt
     7561 gcagtgatct taagtgccca ggcgacagat gtatcagtga ataaagcaac gccagatttg
     7621 tttgcctctt ttccgacacc cgatgcgtta gcagaagctt caatcgatga aatcattctt
     7681 aaaataaaaa cgattggttt gtatcgaaat aaagcaaaaa acatcaaagc gtgtgcacag
     7741 cagctgattg aacgtttcga tgggcaagtg ccaacgtcaa gagaagaatt gatgtctctt
     7801 cctggtgtag gcagaaagac agcaaatgtc gtattggggg atgcattcgg gataccagca
     7861 atcgcagtag atacccacgt ggaacgtgtc tcaaaacgcc tgaggatctg caaactagat
     7921 gctacggtca tggaagtaga agaaacactg atgcggaaag taccacaaga attatgggta
     7981 aagacacatc atacactgat tttttttggt agatatcatt gcacggcaag aaatcccaag
     8041 tgcgaggtat gtcctttgct atcaatatgt caagatggga aaaatcggat gcgtctaaaa
     8101 gaaaaggcgc taaaaaagaa accacgcctg tagacgtggt ttctttaatt gcaaataaat
     8161 gtatgaatta tcttgttatt atggagaaaa gctgtttcgt ttatcttttt tgcatgaaaa
     8221 agtaaatgta catactcagt agctaggatg gtaacttatt acaatttatt gcgataaaaa
     8281 taaaagttgt tatttttatt gggaaaatac ccgatgtaga aaataatgcc ttccaatata
     8341 cctataaaat aagtccagta ttccaaagga ttatataaat aagtgacgta tctatctaaa
     8401 ggtgtaataa aaatgataag tgataataaa aaaataccat ttataactaa acataaacta
     8461 atggatttgg gcggtttcag gctcatcaga aaaatataga ttctggtgaa caacaaccat
     8521 aaaaaagtga gaatcattgc atgagagctt ctttccataa attttccttt aagagtagtg
     8581 cttaaaagta cagaaaaaat aataaatgca aggataggag caattaaagt aaatttattt
     8641 aataataaac aaaatttttc agctttttta ttcttggaat aacgaggtat tgttttcgat
     8701 aaaaaaagat ggtgcagaca aattatgata attaagcata ctatcagata actcaaaatg
     8761 aagccttctt tcaaaaaatt attcaaaacc atatattgta ttttttattt gataataaca
     8821 atgggattat taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt
     8881 ataaacaagt aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt
     8941 ttaagctaaa tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa
     9001 tacagcttgg tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac
     9061 cacgcttgta gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg
     9121 atggtgtatg gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag
     9181 gaggagcaga tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg
     9241 aagacgctgg ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt
     9301 cgctttgact agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag
     9361 tctggacata gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg
     9421 tatattgatc tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc
     9481 agtctgtatt tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg
     9541 ctacgtgtga cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg
     9601 aaatcgaata atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa
     9661 taccaagttt tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat
     9721 ataacccagc gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt
     9781 ctgtgatcat ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt
     9841 cttctgttcc gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc
     9901 cattggcgaa agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc
     9961 catcttgttc ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga
    10021 tcccaagatt ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga
    10081 ctgctggaac attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt
    10141 gattatccca gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa
    10201 tagtttttcc agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt
    10261 tcatcgtaga accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt
    10321 cttctgcgat gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa
    10381 gggtggaggc aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga
    10441 tatcatatag tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg
    10501 tgtagacatt cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat
    10561 cgacgatctt agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta
    10621 cattaacagc ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca
    10681 aaacagtatc tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag
    10741 gggcttgagg catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct
    10801 taccaaagta catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt
    10861 tatttacgta gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca
    10921 tccacgcttc ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg
    10981 aaagtttgat caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt
    11041 tagagagggc agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc
    11101 gatcttctac cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt
    11161 tttcacgctt ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg
    11221 aagatacggt agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc
    11281 agaaaagtcc tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga
    11341 tcttgataaa taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat
    11401 tcttcttcac actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt
    11461 catttgccat tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg
    11521 tccaaataag gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc
    11581 aaagataaag gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa
    11641 tgaacactat tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag
    11701 accccatttt gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta
    11761 aagggaaaag atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga
    11821 tagacgccat tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca
    11881 gcacttctct taggatagtc tactttcacg atttggatag gggtaggctt tttatggata
    11941 accgccaacc cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc
    12001 atcccccgat tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga
    12061 gaggcattct tataataagg ttggccattt ggatagcgca ataccatctt taatcacact
    12121 cctaggccac attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt
    12181 caaaagtaat ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg
    12241 atcctaaaat ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag
    12301 aagggctgga atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa
    12361 tagtagcgga attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt
    12421 ctgattttgg taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat
    12481 tagcagatta tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga
    12541 atcacactcg ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat
    12601 tccctggaaa aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct
    12661 acgaaattcg gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt
    12721 gtttgattta tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat
    12781 gaaaactaga ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca
    12841 agaattcaaa acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa
    12901 tatcatcaaa gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga
    12961 tcgattgagt gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt
    13021 gcaacaaaca gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt
    13081 gtcaaatctt gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa
    13141 accagcacaa cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga
    13201 aaaaacacgt caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc
    13261 tgacttgatc aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg
    13321 tgcttagcga aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag
    13381 gcttcggcta tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc
    13441 catccggtgg aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt
    13501 tttgtctgga agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct
    13561 ttgttttttc tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat
    13621 cagggaatta ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag
    13681 ctatttttca atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg
    13741 ttattcggaa tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata
    13801 aataaggaga ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag
    13861 cgggctagaa gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga
    13921 gaacggacgt gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt
    13981 acgtacagca gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga
    14041 attgtttgaa aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt
    14101 tcctgtagct ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat
    14161 cacaaaaaaa gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc
    14221 actgacggaa actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat
    14281 ggtaactctg gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg
    14341 tggagcacca ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa
    14401 agaccgtcca ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt
    14461 aataggccat aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg
    14521 gttcagtcaa gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga
    14581 tattgaatta gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc
    14641 caatgcagaa gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga
    14701 cttcaaaacg gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct
    14761 aggagaagaa gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt
    14821 aaaaacatgg agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca
    14881 aaaagcaacc aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta
    14941 ttggggaact cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca
    15001 ttcaattgga tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa
    15061 agaaatcaat cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat
    15121 gcctgaaaaa gctagtgcat accgaagtga agtagacagc tatctttacg gcatttattt
    15181 ttcaaaaaaa atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga
    15241 agaattgtcg gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga
    15301 acatcgcgta ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg
    15361 acaatggcaa aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca
    15421 aaatattgaa ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta
    15481 tgatgttttg ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt
    15541 tgatcagctt aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga
    15601 acctgaaaca gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt
    15661 gaaagtaatc gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca
    15721 cccatttatg actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac
    15781 agatttcaaa atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca
    15841 agacatcgat gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca
    15901 tgaatcacaa tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa
    15961 gcaatatcct ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa
    16021 attttatcgt ttattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt
    16081 gacttaccct ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg
    16141 ggtagatgtt gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat
    16201 acgaccaaca aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt
    16261 tggttatttt ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt
    16321 gcagcaagaa atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa
    16381 ctggatgtca gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat
    16441 ggatgcaaca catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta
    16501 ttttaatgta tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa
    16561 tctatagatg ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa
    16621 gtgatcgctg attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat
    16681 cataccaaaa gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac
    16741 cgctttgtga cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa
    16801 aatgagaacg aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag
    16861 gaacagatct cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct
    16921 gaagcggccg aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca
    16981 ttaggagcaa tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt
    17041 tttgatcctg aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg
    17101 acagtgatca atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat
    17161 tacggatatg aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt
    17221 tttctggaat ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac
    17281 aaaaaatgat ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc
    17341 gtaaaagtta cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg
    17401 agtcacaagg aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg
    17461 attcggaatt ggcaggagaa caccgtttat tcggaagaat aggactgtga caagactttt
    17521 gtcacagtcc ttttttcgaa ttcaacaagt aaaactttta agaaatattc agagagtaaa
    17581 attaaaaatt gctgataaac gaagatggaa attttatgta tttttattgg tctatgcaat
    17641 aaataaatta aatattcaga atacaattga ttttaacgaa agggcttcta tcaatggttg
    17701 tgttgtattt atctgcccag gtagagtaaa atagatcatt atctaaaagg taattgttca
    17761 tactatataa gtcatttgaa agtaaaaaga tactgtaaat aaaaaatgtg gttaaataat
    17821 tctcataatc agtgtaagcg ttatcaaaaa tatagcatac ttgctttgta gatgaatgac
    17881 acgatatatg tttggtatgt tctgcaagac agatgaatat ggaggtggag acaatgtctt
    17941 ccaaagaact aacaatgtat ttagagaaag aattggatca actgaaagaa aaggggttat
    18001 acaatacgat cgacatacta gaaagtgaaa atggtgcttg tatcatcgta gacggaaaaa
    18061 agatgatcaa tctagcatcc aacaattatc ttggatttgc caatcgcgaa gaattgaaaa
    18121 aagcatgtat tgaagcaacc gaaacttatg gtgtaggagc aggagcagtc cgaacgatca
    18181 atggttcgct gaaaatccat cagcaattag aagaaaaaat cgcagaattc aaagggacag
    18241 aagcagcaat cgcctttcaa tctggattca actgcaatat gggcgctatc tctgcagtaa
    18301 tgacaaaaga agatgctatc ttatcggatg aattaaacca tgcatctatt attgacggtt
    18361 gccgcttatc cggagcaaaa atcatccgaa ttaaacatca agatatgaaa gaccttgaga
    18421 aaaaagcaaa ggaagcgata gaaagtaaga aatataaaaa aatcatgtat atcacagatg
    18481 gtgttttctc catggatgga gacattgcac gattgccgga aattattccg attgttgaaa
    18541 aatatggact gatcacctac gtcgatgatg cgcacggctc aggcgtaact ggaaaaggtg
    18601 caggaaccgt caagcatttt ggattaagcg acaaaatcga tatgcaaatg ggcacgttat
    18661 cgaaagctat aggtgttgtt gggggttatg tagctggatc gaaaacacta atcgactggt
    18721 tgaaagctag aagtcggcca ttcctatttt ctacttcgct aactccaggt gcagctgcag
    18781 ctgcattggc ttcgattact ttgatgcaag aacatccgga acttgtcgaa aaagtttggg
    18841 aaaatgctaa ttattttaaa gaagaattga aaaaagtagg ctataacatc ggtatgtctg
    18901 aaacacctat tactccagtc attttgggag acgaaaaagt gactcagact ttctctaaga
    18961 agctgatcga acatgggatt tatgctaaac caatcgttta tccaactgtg cctcttggga
    19021 caggcaggat cagaaatatg ccgactgcgg aacatacgag ggaaatgctt gatgaagcag
    19081 tagcagttta tcaaaaaata ggaaaagaaa tggaaattat ttaactaaat ttagtttttt
    19141 cgtctattta aaattagaga acatgttcac gcatatattg ttaatcatct gaagatagta
    19201 gtaaaaaaga tcagggagga tcatcatgaa aaaagtattg gtgacaggat gtttaggaca
    19261 aattggttca gagttgatca cacggctacg tcaagaacta ggcagtgaaa atgtcattgc
    19321 gacagatata cgcatgcctg aagtcattga gaaaaacgat atctttgaga tcctagatgt
    19381 aatggattac gaaaaaatgc gcagcatagc agaacaatat caagtggaca cattgattca
    19441 tttggctgct cttttgtcag ctgttgcaga agcaaaacca caattagcct ggaatttgaa
    19501 cgtgactggg ctggtcaatg cattggaagt cgctagagaa ttccagctga aattttttac
    19561 gccaagttca atcggcgcgt ttggtccaaa tactccaaaa gatcataccc cacaagatac
    19621 tcttcagcgt cctacaacca tgtatggggt aacgaaggta gctggagaac tactatgtga
    19681 ttattattat gtgaaatatg gcgtagatac tcgtggtgtc cgtttccctg gattgatttc
    19741 ttatgcaacc ttgccaggag gcggtacgac agactacgca gtcgatattt attattcagc
    19801 aatcaaagaa ggaaagtaca ctagtttcat tgatcaaggt acatcaatgg atatgatgta
    19861 tatgccagat gcgatcgatg ccattataaa actcatgaat gcagatcctg atcgattggt
    19921 tcatcgaaat gccttcaata tatcggcgat gtcttttgac ccggaagaga tcaaagcatc
    19981 tattcaaaaa atcataccag attttgaaat ggattatgat gtggatcctg tacgtcagtc
    20041 aatagcagaa tcttggccaa attcactaga tgtttcttgt gcgcaagagg aatggggctt
    20101 ttcgccgaaa tacgacttag atgtgatgac aaaggatatg ttggaaaaac tgaaagaaaa
    20161 attggtagag acggtataaa acaagaacca catccaaaaa gttttttata cttttgggat
    20221 tggctatggt atgaaagggg acaagggatg gaagaatatc aagccacgcc agtaaaagaa
    20281 gtaaaaatag aaaatgaatt aaaacgtacg atgggatttt ttactgcttt atcgactgtt
    20341 atgggcacag tgatcggtgc aggggtattt tttaaagccg caagcgtagc agaagttaca
    20401 ggatccgcca gtttgcatat gttttcttgg tttctcggtg gtatgatttc tgtctgtgca
    20461 ggactaacag gagctgaact ggcagctgct attccagaaa caggagggat gattaaatat
    20521 atcgaacgga tttacggaaa tacagcagct tttttattgg gctgggcgca agtcgtgatt
    20581 tattttccag caaatgtagc agccttgtcg atcattttcg gtacacagtt cgtcaatcta
    20641 tttggtcttt cccagtcaat gattgttccc gtagctgtta cagctgctgt atcgatcctg
    20701 ttgatcaatt ttttaggttc taaagctgga ggggcttttc agtcgattac gcttgtctgc
    20761 aagcttattc ctttgtttgt gatcgtcatt ttcggtttgt tccgacaaga aggagtagac
    20821 ttccaactgt ttccgatcca agcaggagaa aatctttcat ttttctcagc cttgggagcg
    20881 ggcttgctag caacgatgtt cgcatacgac ggttggatac acgtaggaaa tatttcggga
    20941 gaattgaaaa agccggcgaa agatttgcca aaagcaattt ctttaggaat catcggaatc
    21001 atgatcgttt atttattagt aaatgcggtg ttcttaagaa ccgcatctat cgacggagtc
    21061 gcaggaaaca gcaatgcggc aagtgacgtt gcaaaaatga tttttggcgg cttcggtgga
    21121 agactggtca cagttggtat cttgatttct gtttatggaa ccatcaatgg ctataccctt
    21181 actggaatgc gtctccctta tgttatggca aaagaaaaca acctgccttt tagcaagctc
    21241 tttgctaaac ttcatgataa aactaaagtt cctgtagccg caggtatctt agagctagtc
    21301 atcgctattg gcatgatgat gatcggtggt tttgatacac taacggatat gctgatcttt
    21361 gtcatttgga ttttttatac gatggtcttt gttggtgtca ttcttcttcg taaaaaagaa
    21421 cctgatttgt ttcgaccata caaagttcca atgtatccgt ttattccact agtagcaatc
    21481 attggaggga cttttatcgt atcaagcacg cttatcactc agaccttttt agcttcgatg
    21541 gggatagtat tgacacttgc tggtatcccg atttatctct atttaaaacg tagatagcta
    21601 aaacattcga attttattag aactgcactt ctctgccaaa caaaatattt tatttaaatg
    21661 aggagtacgt ggaagaaatg tcaaaagtac tcgttaattt tgatcacgta aatgtcgttt
    21721 tgtctacgat gaaatagcaa agtaaaagac agaaatcggg ctcaaccgat ttctgtcttt
    21781 tactttgatt tgcgtaactg aactattcgg cgtacgccgc gataaatatt taataaaacc
    21841 aagcaaccag aaatgaaaat gggaagccaa atcagataga cagggtagcc aagcacttta
    21901 gacaaagcat gtggagtcat tttatccatt tcaagaagtg cttgctgcca agtctgaaga
    21961 ttgaagacta gcatgaaacc cgaaataatc aggagaataa atcctaaata atgaattgta
    22021 gttctttttc ttacataagc gatcgtagca taaaggaaca gtaaaaaaat aggtacgcca
    22081 aaaacaaagt acatattcag catctcgaca ccccctttgt gtttatctta ctttactttg
    22141 aaagaaatga gaaataatag cctcgttact tgcttgaaac agcaaaggac tgctaagata
    22201 agagagatac aaagaatcaa ggaggagtca tatggcaagt tatatcgaac cgattcgttt
    22261 tgcgctgatt gtttttccat ttttagcctt agcgatctca tctgtttttt ttatttatga
    22321 atatcgaaag tatggaacat ttctagtaac aagggcagtt attttgtatt ctttcgtttt
    22381 ttatttattg tgtgcgtatt ttttggtgat cttaccactt ccggcaaagg agacggttgc
    22441 ccaaatgaca gggccaaaga tggagctgca tttatttgct tcatggcaac atttcagaga
    22501 caacacggta ttggtcttgt ctgaacctag tacctacctg ccggcaatga agcagagtgt
    22561 atttttggaa ccagctttta atgttttatt actcatacca tttggcattt atttaagata
    22621 ttatttccgg ctttctttta tgaaaacgat gattgctagt ttctgccttt ctctattttt
    22681 tgaattgacg cagctaagtg gactttattt tatctaccca agaccatacc gcttatttga
    22741 tgtgaatgat ttagtgacaa atacattggg tggaatcatt ggttttgtcg ttacgccgtt
    22801 atttacattt atgcttccta caagaagacg aatggatgaa ctttcttatg aaaaaggaaa
    22861 gactgtctca ttgactcgac gcttggtcgc ttatttgatc gactggacat ttttatctct
    22921 tattaatttg gtagcggcga ttttctttaa aattgcgttc gattcagggg cagttacttc
    22981 tcatatctgg tggcttttat tagaagtagg ggtatacttt atgattgtac cgtttataac
    23041 caatggatgg acacttggca aaaaaattgt gcgtatccgt ttggtggaag aagaccgcga
    23101 acgaatttct ttaaaagcat tgatgatccg ctacgggtat ctgtactttc ttttttatgg
    23161 tttaagctgg ttggggcagt tgcttcagca aatcatgaat tcgacaacga atacggtgtt
    23221 gcagatgagt gcagtattca tttctctcgg tgtcttgtta ctacaaggta tttttatttt
    23281 aaatatcttg ctatcatttt tgagaaaaaa acggattctg ttttatgaaa aagctagtca
    23341 cacatatact gttagcacga ttggccaaac aaaggatgat gattctcgaa attagctgag
    23401 caaaaacgct ttgtctgtgt tataatgcca aagtcgtgat aatttaaaga gaagaggtgc
    23461 acgaatgaat aattttgata tattccgctt caaaccgttt atcaatgaag cgttaaccgc
    23521 aaagggcttc aaacagccca cagaggtcca ggaacgtttg attcctttaa ttgcaaaagg
    23581 aaaaaatatc attgggcaat ctcaaactgg tacaggaaaa acacatacgt ttttgttgcc
    23641 tttgtttgaa aaaatcaatg cagaaaaaga ggaagtacaa gttgttatta cagctccaag
    23701 tagggaacta gctgcacaga tctatgaagc agctacacaa atcgctaaat tttctacacc
    23761 ggagatccgt gtctcgaatt ttgtcggcgg tacagacaaa cagcgtcaat taaatcgtct
    23821 gcatcaccaa cagccacagg ttgtagtagg cacgcctggt agaatattag acatgatgaa
    23881 tgaacaagcg ctgaagattc acaccgcatt tgcatttgtt gtcgatgaag cggatatgac
    23941 attggatatg ggttttttaa atgaagtaga ccaaattgca agtcgattac cagaaaagct
    24001 gcagttttta gttttttctg ccactattcc agaaaaactt cgtccattct tacgaaaata
    24061 catggaaaat ccaatcattg aagaaatcaa accaaaagca gttatttctg aagacattga
    24121 aaattggctg atttcaacaa aaggtaaaga tgagaatcaa atgatttatc aactgctgac
    24181 aattggtcat ccttatttag caatcgtatt tgccaataca aaacagcatg tggatgaaat
    24241 tgccgattac ttgaaaaacc aaggcttgaa agtagcaaag attcatggag acatcacccc
    24301 aagagagaga aaacgagtga tgcgacaagt acagaatctg gagtatcaat atgttgtagc
    24361 gactgattta gctgctagag ggatcgatat cgaaggtgtc tctcatgtta ttaatgcaga
    24421 aattccagaa gatctagact tctttatcca tcgtgtcgga cgtactggac gtaatggctt
    24481 aaaaggaacg gccattacgt tatattcgcc aaatgatgag caagccattg atgcgataga
    24541 aaaattgggc gtctcatttg aaccaaaaga aatcaaaaac ggggaaatcg tcaaaacata
    24601 cgatcgtaat agacgtgcca aacgagaaaa atcaaaagat gtattagatc ccacgctgat
    24661 tggtcttgtg aagaagaaaa agaaaaagat caagcctggt tataagaaaa aaatcgattg
    24721 ggcaattgca gaaaaaaata aaaaagaacg caaaatcgaa cgcagacagc aaagccgtac
    24781 tgctcgtaaa aataagaaaa attcacataa ataaaaaaca agaggttgtg acaaaaggcg
    24841 tgtcacaatc tcttgttttt aagctagact ttttttcatt ccgatacaaa gtacttcatc
    24901 ttcaataaaa ggttctgtgc aagtatgata cccttgtttt tcataaaaat ctacagccgt
    24961 catttcagct actacataac tagtctgaca accttctgaa accgcccgtt tttcagcagc
    25021 ttcaagcaac tgaccgccta acccttttcc tcggtattct tttgctacgc aaaatcgttc
    25081 cggcttgaag caagtaggtg ttttcttttc ataacgcaaa gtagctactg gtcttttttg
    25141 atcaagaaat agataatagg tttgttgcgg gatatctttt ccgtcgaatt ctagttctgc
    25201 aggaatccct tgttctaata caaaaacttg atatctcaaa aagcagctag ctgcgcgtat
    25261 ccattcatcc gctccaacta tttttttcat catattcctc cttgtcatga atagcagaga
    25321 tgtattgatt cctttattct tatcgtacca aaaatcgtgg agtatgacca aaaggaaatg
    25381 aaaataaaaa ttgagatatt gacagtgatc aatagaatgc gtatactaat taagtacgaa
    25441 aaggatatga tttgtttttt aagactcaca gaaaattctt tcttggctga aaaaagaata
    25501 gtcactaatc aaattgctcc ctttttctat tttggtagaa ataccgacgc agctcagcgt
    25561 tatcgagttt aagaggtaat gattacacat cattgcaatc aaggtggtac cgcgagtttt
    25621 cgtccttggc tgtgatggtg tttttttgta tttaatttat agaaagcagg taatgacatg
    25681 aaacaattaa gtagtgcaca agttcgacaa atgtttcttg atttcttcca atctaaagga
    25741 catacgattg aacctagtgc gtctttgatc cccgtgaacg atccaacctt attgtggatc
    25801 aactctggtg ttgcaacatt gaaaaaatat tttgatggtt cagttgtgcc agaaaatcca
    25861 agaatcacaa atgcccaaaa atctattcga acaaatgata tcgaaaatgt cggtaaaaca
    25921 gcacggcacc atacgatgtt tgagatgctg ggtaattttt cgattggtga ctatttcaaa
    25981 aatgaagcca tccactgggc atgggaattt ttgactgatc caaaatggat ggcattcgat
    26041 ccagaaaaac tttatgtaac agtttatcca aaagatacag aagcaaaacg catctggcat
    26101 gaagaagttg gcctgccact agatcacatt attgatgtag aagacaactt ctgggatatc
    26161 ggtgcaggcc catgtggtcc ggatacggaa attttctatg accgtggaga agcttataac
    26221 gatttagcag aagacgatcc tgaaaactat ccaggaggag aaaatgaacg ttatttagaa
    26281 atctggaact tagtattttc agaattcaac cataagcctg ataacacatt tgaaccactt
    26341 cctcataaaa acattgatac ggggatggga ttggaacgca tggtctcaat cgttcaagat
    26401 gcgtcaacga actttgagac agacttgttt atgcctatta tccacgccgt agaaaagcta
    26461 agcaaacaag taaaatatgg tgaaaaccca gtaacagata tttcttacaa agtaatcgca
    26521 gatcatattc gcgccctttc atttgctatt ggcgacggtg cattgccatc gaatgaaggg
    26581 agagggtatg tcttacgccg tttgcttcgt cgtgctgtca tgcatgggaa aaaattaggt
    26641 attgaacaag cattcttata tcgtttagtc cctgttgttg gggaaatcat ggtaagttat
    26701 tatcctgaag tacttcaaca aaaagaattt attgaaaaag ttatccgtac agaagaagaa
    26761 cgtttcaatg aaacaatcaa tgaaggtttg gaaatcttaa atcaagtgat ccaagaagta
    26821 aaaaacgaaa acgggacgac tctagcagga aaagacatct tcaaactata cgacacatat
    26881 ggcttcccgg tagaattaac ggaagaggtg gcagaagatg aaggactgaa agttgatcat
    26941 gctggttttg aaaaagaaat ggatgcacaa cgcgaacgtg ctcgctctgc ccgcagtact
    27001 gaaaaatcaa tgggggtaca atctgcttta ttgacagata tcaaagtaga aagtaaattc
    27061 attggataca cagaacaaga atcagatagt caattattgg tcatcgttaa aggtgagtct
    27121 cttttgaatg aagtcgcaga aggtgaagct caaatgatct ttgatcaaac acctttctat
    27181 gcagaaatgg gtgggcaagt agcggatcaa ggatggatca tgaatgaagt aggcgaaatc
    27241 gtagcagttg ttacagatgt tcaaaaagcg cctaatggtc aatttatgca caccgtagaa
    27301 gtaaaagcac caatgagtga aggacaaacc tatcatctat tgatcgatca atcgatgcgc
    27361 aatcggatca tcaaaaacca tacagcaacc catctactgc acaaggcatt gaaagaagta
    27421 cttggcgagc atgcaaatca agctggttct ttagtcgctc ctggacattt acgattcgac
    27481 tttacccact ttggtcaaat cacttcagat gaattagctg aaatggaaag aatcgtcaac
    27541 gaaaaaatct gggaagctat cccagttgaa acaattgaaa cagatatcga tacagccaaa
    27601 aacatgggtg caatggcttt gtttggtgaa aaatacggac atgacgttcg agtagtaaat
    27661 attggcggct ggtcaatcga actgtgcgga ggcacacatg tagcaaatac agaaaacatc
    27721 ggaatcttca aaatcgtttc tgaatcagga attggtgcag gcgtgcgacg aatcgaggct
    27781 gtaacaagta aagaagcgta cgaactactt gaagaagaag aaaaacaact aaaacaagta
    27841 gcaacaattg ttaaatcacc tcaattgaaa gaagttgttt caaaagcgga acaattgcaa
    27901 cagcaagtaa gagagctaca aaaggaaaat gaacaattag ctagcaagtt agcgaatcaa
    27961 caagctggtg atgtattcaa agatccagaa acgatcaatg gaaaaacaat cattgcagca
    28021 caagtaaaag tgaaagatat gaatcagctg cgtcaattag ctgaccaatg gaaacaaaaa
    28081 aatatttcag atattcttgt tttagcaaac gaacaagaag gaaaagtcag tctgctagcg
    28141 gcaatgacga aagaatcaaa tgaagctgga ctaaaagctg gcgacttgat taaagcaatc
    28201 gcaccgaaag taggcggtgg cggtggtgga cgtccagaca tggcacaagc tggcgggaaa
    28261 aatcctgctg gtattccaga tgcacttaaa gctgcgaaag aatgggttgc gcaacaatag
    28321 ggcgtttacg tttgacagaa aaacaaaagt tcaaacattg aacgaaacat gattatgggg
    28381 gcgaagacaa acaagtcttg ccctcatact tttttcaatt ggatggcgca tctaatcaaa
    28441 tggtcggatt cggatggtct ttagttgacg aaagtgacag aaatttttac gattagtata
    28501 aataaaaagg ggtgaaaaaa tgaatagtag aaataagacc tttcgactag tcttacgtgc
    28561 gatcttgtta gcaatcatca tcgtacaagc gatggttcct tggctggggt ttattccatt
    28621 aggattcatt agtttaacaa ttatccatat cacagtaatt attgctgcag tagtattagg
    28681 cccaaaagat ggcatggtga ttggcttgtt ttggggaatc gctacaattg ttcgtgccta
    28741 tgccatgcca acaacgccat ttgatacatt agtgttcacg aatccgatta tctcggtagt
    28801 tcccagagta cttgttggct tagtagcagg cttggttttc cactggattt atcaaaaaaa
    28861 taaatcaata acgatcagct cagcctttgc aggggtactg ggttcattgg tcaatacagt
    28921 cttagtgtta ggattcatgg gattatttta tacaggtgca acggcagatg cctatggtgt
    28981 agactctgct cttttattta aaaccttagc aggggttgca gcaatcaatg ggataccaga
    29041 agcaataggt gcgggaatca taacaccatt actagcaaaa gcgttatttg cagcaacacc
    29101 gttgaaacca gaataatgac catcttttaa tagtaatagg acgcacgata gatagaaaaa
    29161 ggaagagagg agaggaaaac aatcgtcctc tccatctttt tacctgagca acaagcaaac
    29221 tagaaggggt aaaaaacttg gctaagaaac aagaagaaaa aaagaaacaa ataccgcaac
    29281 agcggacaaa aaaaggagta ctagcgggta tcttaggatt ggttacgaat ctgatcttgt
    29341 ttgtctctaa gctaatgatc gggctttttt caggaagtgt ctccattatg gctgatgcag
    29401 tgaacagtct atcagatact gcttcatcca tattgacttt gatcggattt aaaattgctg
    29461 caaagccagc agatcaggaa catccttatg gacacgaacg cttcgaatat atcagtgggt
    29521 tatttgtttc gatcatcatt acttatgtag gatttcaatt tttagagtct tctgctgaaa
    29581 aaatcatcca tccagaaaat gtctctttaa cacccatcgt cttttttgtc ctaatcattt
    29641 ccatcttttt gaaatttgca caaggcaaaa tgtatcaggt tattgcgcaa tccattgatt
    29701 ctgaaacatt gagagctaca gcaacagata gttataatga tgtctttact acactggctg
    29761 tattgctttc agcagcaatc gaatgggtaa ctggatggcg tattgatgga tatataggtt
    29821 ttgctttagc attatatatc ctttatagtg gattgacgat gcttcgaaat tttgtatacg
    29881 aactattagg aagtcgccca acgccagcag agattgaaga aatggaagag catttaaatg
    29941 cttgcgatga tatacttggc tatcatgatt tattggtgca taactatgga cccaataaac
    30001 gctttgcatc agtccacatc gaagtagatg aatcaatgaa tttgaatgtg gctcataaga
    30061 ttattgatct gatagaaaaa gactttaaaa agtctttgga tgtggaactt gtctgtcact
    30121 tggatccaat gcctgttgat aacgaaaaat actataatat cttgcggcag ttaaagcaaa
    30181 ttcttcttga aacaggtaca gggcttaata ttcatgattt tagagtaatt catcaaggaa
    30241 aaacgctgca atttgatgta gtggtccctg agaaattcca gtttgttgat acagaactag
    30301 aaagaatctt acgtagtcaa atagaagaaa aaatcggaga ttaccaattg gaaattacgt
    30361 ttgatcacaa ttatctttta tattaaatga gaaactataa aaagactcct taaagttttt
    30421 aatttaaaga gtcttttttt cttttaattg tttatggaga gcctgacgtg caagattatc
    30481 tgctccttta tttttgtttt cgggcaacca ttgcaggatc aataaagaaa attcggatag
    30541 aagttcttgg attctttgaa ggtagggaag gaagagctcg ttcttcgttg cgtttttgtc
    30601 gaccgtagaa actagtgttt tgctgtctga aaaacagaaa atcgtttcat tctgtaagtc
    30661 gtttttcttt agaaattcta aagtttttaa aaagacttcg aactctgctt gatggtttgt
    30721 ccctatagaa agcgggatag atagctgttc ttgtttacct tgatagacaa tcaagattcc
    30781 acctccacta ggaccagggt tgccttttgt agaggcatca atgtatactt ttaacataaa
    30841 aagagattct cctttttgtt caaactaatg ttatggtaag attatatcat tactgaatcg
    30901 gtgagaggtt agagaatgaa aaaaaatatt cgatggcagc ctgaactggc acatacgatc
    30961 atctattggt cattgacctt gatcattctg ttttttagtc tgattctttc tttagaaaac
    31021 acaggtcctt attggaaaag caattttgtt ttaggtattt ttcttgtttt tctatttcta
    31081 ggtttgcggc gttcttttat tttaaaatca aactctgtga ttatacgtta tgctgctttt
    31141 tggaaagacc gagaaatatc tgtcggacag attcgatctt tgacgccaac taatactggg
    31201 gtgcaaatga tgttgcaaga tgagaaagcc ccatctgttt tcatgatgcg aaaaaaagat
    31261 caagtagtcc tttttgatca ttttgaaaaa aacggaccca aatcagaatc aattccttat
    31321 ccttatacga aaaaaagaaa aagctaattt taaaaatcag aacctaaaaa aacgaatttt
    31381 tacaggaaaa gaaaagagtg agacgtacgg ttcatcccgt ttagcgtctc actctatttg
    31441 tttatctatt catgcatact agtatcggta gtctgaacgt tgcctttctt gacatgggca
    31501 gcttgtgttc ctcgattccc ttcgatgatc tcaaattcga ccacttgatt ttcttccaaa
    31561 gttttgaatc cctcttcttc aatcgcagta aaatgtacaa aaatttcttc tgtgtcatca
    31621 taactgataa agccgtatcc ttttttgttg tcaaaccatt ttacaattcc tgtggtcaaa
    31681 gcactcacga cctttctaaa gtctgatcat agccttcatt ataaagagta tttataagta
    31741 cgtcaaataa attaaaaacc tgtaatttta tgtttttttt ctgaataaaa aaaggtataa
    31801 ttggcatatc ttaacaaaga agatattttg ttgaataaag ttcgtgaaaa ggggtaatca
    31861 aatgaagaat gatctgcaaa tttcacaaga aacagagcta gaaccgattg ttgaagtggc
    31921 tagtaaatta gatcttaagg aagacgattt ggaactgtat gggaaatata aggcgaaaat
    31981 caatttttct ggaatcaatc gatcaaagga taacgctgag gggcatttga tcttagttac
    32041 ttccatcaat ccaacaccag ctggcgaagg aaagtcaacg atcactgtag ggttaggaga
    32101 cgcgctcaat aaaatcaata aaaaatctgt tattgcattg cgagaaccct cacttggtcc
    32161 tgtgatggga atcaaaggtg gtgctgcagg cggaggatat gcacaggtat tgcctatgga
    32221 agatatcaac ttgcatttta ctggtgacat gcatgctatc acaacagcta ataatgcatt
    32281 atctgctctt ttagataatc atattcatca aggaaatgaa ttgaacatcg atgcccgccg
    32341 agtgatttgg aaacgggtag tcgatctcaa tgatcgtgaa ctgcgtaaag taattgttgg
    32401 cttgggtggg ccaatccaag gtgttccaag agaagatggg tttgatatca cagttgccag
    32461 cgaaatcatg gctatcttgt gtcttgcggc agaccttgaa gatttaaagg ctcgtcttgc
    32521 aaggatcgtt gtcggctata catttgaccg tcagcctgtg actgctggag acttgaaagc
    32581 agaaggcgct ctggcattac tgctgaaaga tgcaatcaag ccgaatcttg tacaaacaat
    32641 ttacggaaca ccagcttttg tccacggggg accgtttgcc aatatcgctc atggctgcaa
    32701 tagtatttta gctaccaaga cagcattgag attagcagat tacgttgtca cagaggcagg
    32761 atttggtgca gatcttggcg gagagaaatt tttagatatc aaagtaccta acttgaaaaa
    32821 agcgccggat gctgtggtga ttgtcgccac tgtccgtgca ttgaaaatgc atggcggaat
    32881 gaaaaaagat gaacttaaaa atgagaatct tgatgctttg aaagtaggtt ttgcaaattt
    32941 aaagcgccat atacgtaata tggaacaata tcagctacct gtgatcgtcg caatcaatga
    33001 attcgtaaca gatacagaca atgaactcac actgttggag cacttgtgtg aaaatcaggg
    33061 gattcttgcc aagagagcga gtgtatgggc agatggagca gaaggcggcg ttgatttagc
    33121 aaaagctgta gtacgattga ttgatagaaa agaagctaat tacaagccat tataccgcct
    33181 agaagaaacg atacaagaaa agacagaaac aatcgtcaag aaaatttacg gaggaaatgg
    33241 tgttgttttc agcaaaaaag cgcaaaaaca aatagaagag tttacgaaga atggatggga
    33301 caaactgccg atttgtatgg caaaaacaca gtattcattt tctgatgatc cttcactgct
    33361 aggtgcaccg gaagatttca ccatcacgat ccgcgaaatc atcccaaaat taggggcagg
    33421 atttttagta gccttgactg gagatgttat gacgatgcct ggtttgccta aaaaacctgc
    33481 tgcattgaat atggacgtga caaatgacgg agaagtgttg ggattgtttt aagcttgatt
    33541 ataatctacc atcgaaggag ctgtattttg actacagctt ctttttttag acgataggga
    33601 attaattttg tttacactag gatcattctt tttctttatt gtattttgag ctatactaaa
    33661 gcataatagg agggtatgat gaaaacgaca tttataagaa aaaccggttt ttacggtatg
    33721 ggtagctcga ttcagctaag aatcaacaat gaaaaacgca gtgttctcag tcatgaacaa
    33781 aagataacgc ttgatctgga agtgcccttt acgatgcagg tcacctttta ttggctaaaa
    33841 agccccgttt atacagtgaa agaagcaaag cctgcttatg tgatcacaat gaattacttg
    33901 attcttcaaa tctatccgtt tttatttcta gcaactgggt tgggggccgt tttcctacaa
    33961 aatttatttt tcagtttttt tgcagttatt gtgttgattg cgttcttttt ctatataaaa
    34021 aaccgggcat atttgatcaa ggaggaaaat tatggcaaac tctgatcttt ttttaatcag
    34081 tttcaatcga atcgaaaaat ggatgagaga cgagatggga aatgcacgaa atatgggatt
    34141 taccgaactt gtcagacgcc tagctcaaag aaaacaatta atgatcagaa aatacgaaga
    34201 tgatctttta cagcttgctc agttaaggaa tgcgatcgtc catgatcgga tcgcagtcga
    34261 ttttgtcatt gcagagccaa atgattggac agtcaagcga atccagctga tcgaacaaga
    34321 actgattcag cctgaaaccg tgctgcctcg atttgcaaaa cgtgtaacag gttttgaaca
    34381 agatcttccg ttacttgaac tgttaaagat agtagcagaa aaaaggtatt cacaatttcc
    34441 gttatacaat aaaggaaaat ttgtagcatt gattacttta cgtaatatcg ggttttggct
    34501 agcaaaagaa agccaaaaag gtccggttga tttaacaaat aaacgagcgt tggatttgat
    34561 catccaaaac ggaaagtaca caaattatca ttttgttcca gctaaaacac atatttacga
    34621 ggttgaagcg atgtttcgtg agcaagggac tttggaagcc gtacttatca ctaaagatgg
    34681 gaatcccgat ggtaatctgc tcgggatcgt acgacctcgt gatatttata aacaaataga
    34741 aaaggattga ttttttgtta attatttatt ggatattcag cgctttgcta gtaggagtgg
    34801 atcagttggt caaatggtgg atcactgata atctagcgct tggagagacg aaaaatctta
    34861 taccaggtat tttgtcactg aatcatattc gaaacactgg agccgcatgg agtatgctag
    34921 aagggaagat gtggttcttt actatagtga cactcattgc agtcgttgtg attctcacat
    34981 tgatgattaa aaatcgtgaa aaaggtaatc gctggttcat gattggattg agtttgattc
    35041 tagctggtgc gattggcaat tttatcgacc gtattcgtct tggctatgta gtagatatgt
    35101 tccagacaga ttttatgagc tttccgattt ttaacgtagc agatgtgaca cttgtatgtg
    35161 gagtgatttg tatgttaatt tatattattt tagatgaaaa ggatcaaaga aaaaaatgac
    35221 agaacttaaa acgacgattc accatgaatc tggtaggatc gataaagtat tgactaattt
    35281 attcaccgat tacagtcgtt cgcaaattca gctgtggctg aaaaatggag cggtttctgt
    35341 caatggacag ccagtcaaag caaattacaa agtaaaacaa ggagacgaga ttactgtctt
    35401 gatccccgaa ccagaaacat tagatgtggt cccagaaaat atcccgttga cgatcgttta
    35461 cgaagatgaa gatgtagcgg tgataaacaa acctcaagga atggtcgttc atccttcagc
    35521 aggtcatacg catggcacaa tggtcaatgc gctgatgtac catatcaagg atctttctac
    35581 gatcaacggc gttattcgtc caggtattgt tcaccgaatc gacaaagata cttccggact
    35641 gctaatggtt gccaaaaatg accaggcaca cgaatcatta gctcagcaat taaaagataa
    35701 gacctctttg cgcaaatatg ttgctttagt ccatggagag attcctcacg aaaaaggaac
    35761 catcaatgcg ccaatcggcc gttcgaagga aaaccggaaa atgcaggcga taagagaaga
    35821 tgggaagtcg gctgtcacac attttactgt attggaacgt ttcgaaggat ttactctggt
    35881 tgaattaaaa ctagaaaccg gaagaacaca ccagatccgt gtgcatatga agtatatcgg
    35941 ttatccgtta gctggagatc cagtatacgg accgaagaaa actttgaaag gcaatggtca
    36001 gtttctccat gcgcaaatgt taggttttac gcacccgact acaaacgaaa agatgatctt
    36061 tgaagcacct cttccagaag tttttgaaaa aactttagaa aaattaagaa aaaacattgc
    36121 attttaattt agataacggt atagtaatta acaacgaaag cataaaactt aatagaattc
    36181 ctttaagttt agtcccgtga ggctaagaag ggtgggagca aggatacgta tggtgcgcca
    36241 taagtagatt gctcattgac atagtatagc tatcagtgta tcagtatacg ctcagtctaa
    36301 acattcctcc tgtcctctta gggcaggagt ttttttatgc aaaaaagtag ggggaatgaa
    36361 aatgcaagca aaagaagtag tagatcaggt aaccatgaag cgagcattga ctcgaattac
    36421 ttatgagatt atcgagagaa accatagtat ccaagatatc gtattggtag gtatcaaaac
    36481 acgaggaatc tacattgcat caagaattgc cgaacgcctg aagcagctag aagatatcga
    36541 tattcctgta ggagaactgg atatcacttt ataccgagat gacaaaaaag aaaatccaga
    36601 agaaccggaa cttcattctt ctgacatccc agtttcctta gaaggaaaag aagttatttt
    36661 gattgatgat gttttgtata caggacgaac gattcgagca gcaatggacg cagtaatgga
    36721 ttttggcaga ccaagaaaaa tttcattagc agtcctggtc gatcgtgggc atcgagaatt
    36781 gccaatccgt gcagattatg ttgggaagaa cattccaaca tctcgggcgg aagagatttt
    36841 agtagagatg caagagcttg atggacaaga tcgcatcatg attttgaaag aggaagatta
    36901 gaggagagag aaacatgtcg gagaaaaaag gatttcataa tgatgacgtg gtgttagata
    36961 tccacgatcg cccaacccca ggacattggg taggattaag tttacaacac ttgttcacga
    37021 tgttcggagc aaccgtgtta gtccccatct tagtaggtat cgatccaggt attgcgctag
    37081 tcagttcagg actaggtaca ttggtgtact tatttactac taaaggaaag atacctgcgt
    37141 acttaggaag cagcttcgct ttcattgcag cgatgcagct tttgatgaaa acagatggtt
    37201 atccagcgat tgcacaagga gcagtcacaa ctggattagt ctatttgatt gttgcgctga
    37261 tcatcaaaaa gatcggttca gcatggctgg ataaaatctt gcctccaatc gtcgtcggtc
    37321 cagtcatcat ggttatcggg ttgggacttg cggcaaatgc agcaacaaat gctatgtata
    37381 atcagggcac gtatgatttc aagtatattg ctgtagcgct gatcacatta ggattaacaa
    37441 ttttcttcaa catgtggcta agaggttttc tcggattgat tccgatttta ctaggtatta
    37501 ttagcggata catcgtagcc ttgctgtttg gaatcgtgga tactaagcca atcgtagacg
    37561 ctgcctggtt tgctgttcct aactttgaga ttccctttgt acaatatgaa ccaaagctat
    37621 atcttggagc aatcacaaca atggcaccca tcgcttttgt gacgatgaca gagcatatcg
    37681 gccatcttat ggtattgaat aaactaacta aacgtaattt ctttgaagaa ccgggtcttc
    37741 ataagacgtt gacaggtgat ggattagcac aaatcgtggc agcctttgtc ggaggtcctc
    37801 ctgtaacaag ttacggtgaa aacattggtg ttctggctat cacacgtgtc catagcgtgt
    37861 ttgtgatcgg tggagctgca gtatttgcag tcattttagg attcgtagga aaattaagcg
    37921 ctttgatttt aagtatccct ggaccagtca tctcaggaat cagttttatc ttatttggag
    37981 taattgccgc aagtggaatg aagattttaa tcgagaacaa aatcgatttt gataaaaaga
    38041 aaaatctgtt gattgcttca gttatcttag tagtaggaat tggcggactc gtctttgaag
    38101 taggcacatt tacattgtcg gcaatggcat tagcaactgt acttggcatc attttaaatc
    38161 ttatcttacc agaaacttca cgaagcgaag aaaactaagg aggaaacatt atgatcatca
    38221 aatcagaacg tatcagctta aagcatttat tgaccgttga ggcacttact gatcaagaag
    38281 ttatgggctt gatccgcaga gggcaggaat tcaagcaagg tgctaattgg actccgcaaa
    38341 agcgccagta ctttgctaca aacctctttt tcgaaaatag tactcgcaca cataaaagct
    38401 tcgatgtagc ggagaaaaaa ctagggctag aagtgattga atttgaagca agcacaagct
    38461 ctgtccaaaa aggggaaaca ctatacgata cagtactgac gatgtcagca ttaggcgtag
    38521 acgtagcggt tatccgtcat ggtgatgaga actattatga cgaactgata caaagtaaaa
    38581 caatccagtg ttcgattatc aatggaggag acggaagcgg acagcatcca acccaatgct
    38641 tgcttgattt gatgaccatt tatgaagaat ttggtcattt tgaaggtctg aaagttgcca
    38701 tcgtaggtga tatcactcac tctcgcgtag ctaaatccaa tatgcagatg ttaaaacgtc
    38761 taggcgcaca agtattcttc tcaggtccta gagaatggta cgacgatgaa ttcgaagtgt
    38821 acggacatta tatgccattg gatgaactac tagatcaagt tgatgtcatg atgatgcttc
    38881 gggtgcaaca cgaacgccat gatggaaaag aaagtttctc aaaagaaggc taccatcagg
    38941 aacatgggtt aacagttgag cgtgcgaaga agttgcaaaa acatgcaatc attatgcacc
    39001 cagcaccagt taaccgtgat gtagaattag ctgattcatt agtggaagga ttacagtcgc
    39061 ggatcgttca gcaaatgagc aatggagtat tcgtcagaat ggcaatctta gaagcagtgc
    39121 taaatggaaa agcgtaatta taggaggatg aaaaaatgaa aacactcatt aaaaacggtc
    39181 agatcaatac acgaaaaaat atgacgacac cagcagaaat ttggatagaa gatgggcgaa
    39241 tcaaagcaat cggtacagga ttctcagaag ccgaatttga tgaagtgttt gatgcaaagg
    39301 gacaattgat cacacctggt ttagtggacg tccatgttca tttgagagag ccaggattta
    39361 catacaagga gacgatcgaa gctgggactc gctcagctgc tcgtggcggt ttcactactg
    39421 tatgcgcgat gccgaattta aatcctgtac ctgatacggc agaaaagctg agacaagtat
    39481 atgacatcat tagaaaagat gcagttgtga aggtattgca gtatgcgcca atcacagaaa
    39541 atctgcgaag tgagaaatta gttgatcaag aagcactgat tgaagaaggt gcttttgctt
    39601 tcacaaatga cggtgtaggt gtccaaacag ctgggacgat gtatctggct atgaaagaag
    39661 ctgcaaaaaa caataaagcc ctagtagccc atacagaaga tgaatcttta ttatttggcg
    39721 gcgttatgca cgctggcaag aaggcagaag aacttggtct tcccgggatc ttaagcgtaa
    39781 ccgagtcttc tcaaattgct agagatctgt tgctagctga agcaactggt gttcattacc
    39841 atgtttgcca tgtttctact aaagaaagtg tccgtgtaat cagagacgca aaaaaagcag
    39901 gaatccacgt aacagcagaa gtttcacccc atcatcttat tttgatcgac gaagatattc
    39961 ccgaagattt cggcttttgg aaaatgaacc cgccgctaag aggacgggag gacagagaag
    40021 ctttgatcga aggcttgctt gacggtacga tcgattgcat cgctacagac catgcccccc
    40081 atggattaga agaaaaaagc caaagtttca tgaaatcacc atttggtatc gtaggaagcg
    40141 aaacagcgtt tcaactgatc tatactcatt ttgtagaaac tggtcgattc acgttggaac
    40201 aagtgatcaa ttggttggca gttaaaccgg ctgagatttt tggtttgaat gcaggaacgc
    40261 taacggttgg tgcccccgct gatgtagcag tttttgatat tacacaaact tgcacgatcg
    40321 ataaagaaga ctttttatca aaaggggaga atacaccttt tatcggctgg aaagtaaaag
    40381 gcgaaacaca aatgactttt gtcaacggaa aacttgtgtg gcagaaggga gaataaaagt
    40441 atggaacgtt tgcttatatt agaagatgga acagttttcg aaggaaaggc ttttggtgca
    40501 gatgctagtg tcttcggaga aatcgttttt acaacaagta tgactggtta tcaagaaact
    40561 atcactgatc aaagttttaa cggtcaaatc attacattta cctatcctat ggtgggtaat
    40621 tatggggtaa atagagatga ttatgaatcg atttctccaa catgcaaagg agtagtagta
    40681 aaagaacatg cacgtgtagc ttcaaactgg cgaaaccaaa tgacgctaga ttcatttttg
    40741 aaacaaaaag gaattcctgg aatatcaggt atcgatacgc gcgcccttac tcgcaaaatc
    40801 cgtgaagtcg gaacgatgaa agctagtata gttgatgctg gagattcctt cgaacatgca
    40861 tttgatcagc tgaaagcaac cgttctagca accaatcaag tgcagcaagt ctcaactaac
    40921 aaaccttatc caagtccagg aacaggtcgg aaagtcattg tcattgactt cggcttgaaa
    40981 catagtattt tacgagaatt gagtaaaaga aactgtaacc tcacagtact tccctataac
    41041 acagatgccg agacgatttt agcgctatca ccagacggag tcatgctgac gaatggacct
    41101 ggtgatccaa aagatgtgcc agaagcaatc gaaatgatca aaaaaatcca aggaaaagta
    41161 ccgatttttg gtatttgtct cggtcaccag ttatttgctt tagccaacgg tgcagatacc
    41221 tataaaatga aattcggaca tcgaggatta aatcacccgg tacgagaagt agcgaccgga
    41281 agaattgatt ttacttctca aaatcatggc tatgcagtcg atgaagccac gattgatcca
    41341 gaaaaactca tcgtaactca tgtagaagta aatgacggaa cagtagaagg agtcaaacac
    41401 agagattatc ccgctttcag tgtgcagttt catccagatg ctgcccctgg tccgcatgat
    41461 gcactacatt tatttgatga atttatggaa atgatggacg caggaaagga gcagtaaaca
    41521 gatgccgaaa cgtacagata tcaagaaaat tatggtgatt ggatctggtc cgatcatcat
    41581 tggtcaagcc gcagaatttg actacgcagg aacacaagcc tgccttgcct taaaagaaga
    41641 aggatatgaa gtggttttag taaattctaa tcctgcgacg atcatgacgg ataaagaagt
    41701 ggcagatcaa gtatatatcg aaccgatcac acttgaattt gtatcaagga ttcttcgaaa
    41761 agagcgtcca gatgctctcc ttccaacttt aggcggacag acaggcctca atatggcaat
    41821 ggagctggca gcatcaggta ttttagaaga attgaacata gaacttctag gaacaaagct
    41881 ttctgcgatc gatcaagcag aagatcgtga tctattcaaa cagttgatga aagaattgaa
    41941 tcagccaatc cccgagtctg aaatcgtcaa tacagtagaa gaagctgtag attttgcaaa
    42001 taaaatcggc tatcctgtca tcgttcgtcc agcctttact ttaggcggaa ctggtggagg
    42061 tatgtgtgaa aatgaagaag aattacgtat cgtatcagaa aatggattaa gtctttcccc
    42121 cgctacccaa tgtttgattg aacgaagtat tgcaggtttt aaagaaattg aatatgaagt
    42181 gatgagagat tcggctgata atgcaatcgt tgtctgcaat atggaaaatt ttgacccggt
    42241 gggtatccat acaggtgatt ctatcgtatt tgcccctagt caaacattgt ctgaccatga
    42301 atatcaaatg cttcgtgatg cttctctttc gattattcga gcacttaaga tcgagggagg
    42361 ctgtaatgtc caactcgctc ttgatccaca tagttttaat tattatgtga ttgaagtcaa
    42421 tccgcgtgtt tctcgttcat ctgcgttagc aagtaaggcg actggctatc cgatcgctaa
    42481 gctagctgct aaaatagcgc ttggattaac attagacgaa atgaaaaatc ctgttacagg
    42541 aacgactttt gcagaatttg aacctgcatt agattatgtt gtagctaaaa ttcctcgctg
    42601 gccgtttgat aagtttgaaa acggagaacg gcttttaggc acgcagatga aagcaactgg
    42661 tgaagtgatg gctatcggtc ggaatatcga agagtcttta ttgaaagctg tgcgttcttt
    42721 agaaatcggt acacaccata tcgaacttcc tgagttggca gacatcacgg acgatgacct
    42781 aatccaaaaa gtggttcgag cacaagatga tcgcctgttt tatgtagctg aagctattag
    42841 aagagggtac accatagaag aattagcgga tttgacaaaa atcgatttat tctttttaga
    42901 taaactgttg catatcgtag aaatcgaaca gcagttgaaa cagcagccgt tggatgacaa
    42961 gatattgaaa acagcgaaac aaaacggttt tacagacaaa aaagtggcgg agctgtggga
    43021 aataaacgaa gaagccgttc gccagatgag aaaagaaaat gatttgattc ctgtatataa
    43081 gatggttgac acttgtgcag cggaattcga atcaaaaaca ccttattttt atagttccta
    43141 tgaatatgaa aatgaaagtt cacgatcaga aaagccctca attctagtac tgggatctgg
    43201 tcctatccgt atcggacaag gggttgaatt tgactatgcg actgtgcatt ctgtcaaagc
    43261 aatccagcag gcaggatacg aagcaatcat catgaacagc aatcctgaaa cagtttcgac
    43321 tgacttttct atttcggata aattatattt tgagccattg accttcgaag atgtgatgaa
    43381 tgtgatcgag ctagaacagc cgataggagt aatcgttcaa tttggtggtc agacagcaat
    43441 caacttagcc gaacctttga ctgctgctgg tgtaaaaatc ttagggacaa cgatcgaaga
    43501 cttggatcgt gcggaaaatc gtgatttatt cgagcaagcg ctgaaagagt tggatattcc
    43561 tcaaccttta ggggatactg ctacaagtaa agaagaagcc gtggttatcg cttcgagaat
    43621 tggttatcca gttcttgttc gtccaagcta tgtattaggc ggacgtgcga tggaaatcgt
    43681 tgaaaaccag cgagatttag aagattacat ggaacatgct gtgaaagcat ctccagaaca
    43741 tccagtacta gtggaccgtt acttgcttgg tggtgaatgc gaagtggatg cgatttgtga
    43801 cggtgaaaca gtactcatcc cagggatcat ggagcatatt gagcgtgctg gtgtccattc
    43861 aggggattca atggctgtgt atccacctca aacattatct gaatcgatca agaaaacgat
    43921 cgaagattac acgatccgct tagcattagg tttgaattgt gtcgggatga tgaatatcca
    43981 gtttgtcatc catgaaaatg aggtttatgt gatcgaagtc aatcctcgag caagtcggac
    44041 tgttccattc ttaagtaagg tgacaggaat tccaatggca caaattgcga cgaaagctat
    44101 tttgggagag aaactaaaga cacttggtta tgaaaacgga ctttatccag aaacaaaaga
    44161 agttcatgtt aaagcacctg tcttttcttt tacgaaattg cagaaagttg atacttactt
    44221 agggcctgaa atgaaatcga ctggagaagt aatgggatct gacagacaat tagacaaagc
    44281 tttgtacaag gcattcgaag cttctggatt acacttgcct gaatatggag ccgtattatt
    44341 tacgattgcg gacgaaacaa aagaagaagc actagaatta gctaaacgtt ttacagaaat
    44401 tggctatagt ctgataggaa cgaaacatac agctgcttat ttcgaaaaaa atggtctggt
    44461 cgttgaaaca gtagcgaaaa tttctgagga agcagcagaa aaaaatgtag tcgacttaat
    44521 aagagatggt aaaacacaag tggttgtcaa tacgattgat aaagatcggg gaaatgcttc
    44581 taaagacggt ttcatcatcc gaagagaagc agttgaacat ggtattccat tgtttacttc
    44641 tttagacaca gcagatgcga tcgttcgagt gatggaatcc cgtgcttttt caactaaccc
    44701 tatttaacgg cgagcacatg ttaagacaaa aagacgaaaa accgttgcag gaggggacag
    44761 atgaaacaag aaatgatgga aatcgttcag caaaaacagc tggcaccaaa gatttttgaa
    44821 atgacattga aaggtgatct agtaaaagaa atgcagcaac caggacagtt cttgcatatt
    44881 ctcgtgccgc gtgcagactt gctattacgc cgaccgatta gcttgaatca tatcgaccac
    44941 gaaacaaata cttgccgtat catttatcgg gtggaaggtg aggggactag agtcttctct
    45001 actctttctg ccggagacca tttagatgtc atgggtcctt taggcaatgg ttttgatttg
    45061 tccaatcttc atacaggaga cgaagtattt ataatcggtg gaggaatcgg tgtccctcct
    45121 ctatatgagt tatcaaaaca gttagtcgaa aaaggaatta agccaacgca ttttttaggt
    45181 tttgccacac atgaagtcgt ttattatgaa aaagaattta atcgtctagg agaaacaaga
    45241 atcgctactg acgatggaac atacggtatg cacggaaatg tcggtaattt attgttagga
    45301 acgaagacgg aacctacagc tgtttttgca tgtggttcaa acgggttatt gaagacagtg
    45361 gaacagctgt tttcttcgca tcaaaatgtc cagttatcat tagaatcccg catggcatgt
    45421 gggatagggg cttgctatgc ttgcgtttgt catacgccgg aagatgaaac aggaacaaaa
    45481 agtgtgaaag tttgtgacga aggaccgatt tttaaaatag gagaggtaat tatatgaatg
    45541 agaatccttt agcggtcaaa cttcctggcc tagaattaaa aaatcctatc atgccggcaa
    45601 gcggctgttt cggttttggc aaagaatacg gaaaatacta tgatttgaat cagcttggat
    45661 cgatcatggt caaggcaacg actccaaatg cccgctttgg caatcccacg ccaagagtgg
    45721 cggaaacacc atctggcatg ttgaatgcaa ttggtttgca aaatcctggt ctagacgttg
    45781 ttatgcataa acttcttcca gaattagagg agtacaatga gttacccatc atcgcaaatg
    45841 ttgctggtgc ttgtgaagaa gactatgtag aagtttgtag caaaattggc gaagcaccaa
    45901 atgtgaaagc aatcgagctg aacatttctt gcccaaatgt caaacatggc ggaattgctt
    45961 ttggaacaga ttctgatgtt gcttttcaat taacacaagc agtaaagaaa gtttcttctg
    46021 ttcctgtcta tgtcaaattg tccccaaatg taacagacat cgttccaatc gctcaggcaa
    46081 tcgaagctgg aggggcagat gggtttacga tgatcaatac tcttcttggt atgcggattg
    46141 accttaagac aagaaaaccg attttagcca atcaaacagg tggactctcc ggaccagcaa
    46201 tcaagcctgt cgctattcgt ttgattcacc aagtagcaag tatatccagc cttccaatca
    46261 ttgggatggg cggcgtgcag acagtggatg atgttcttga gatgtttatg gctggagcaa
    46321 gtgctgtagc tatagggacc gcgaatttca ccgatccgta tatctgtcct aaactaatta
    46381 aagagctccc tgtgcgaatg agcgaactag gcatcgaatc gctggaaaga ttaatcaaag
    46441 aagtgagaga ggaacgtgaa cgatgaatca actagaccaa cgaccaatta ttgcattaga
    46501 tttttcaact aggcaagagg tagaagactt tcttcgattt ttcccgaaag aagaaaaatt
    46561 gtttgtgaaa atcggaatgg aattgttcta ccaagaagga cctgaaatcg tacgttatct
    46621 aaaagaggct ggtcataatg tatttttaga tctgaaactt cacgatattc cgaatacggt
    46681 cgaaaaagca atgcggggat tggcaaagct tggtgttgat ctcacctgtg ttcatgccgc
    46741 tggcggtatt cgtatgatgg aggcggcaat gcgaggatta gaagagggga ctccagaagg
    46801 tggaaaacgt ccgctacttc tagctatcac tcagcttact tctacaagtg aagaagaaat
    46861 gcatgccgat caactaatcg aagtttcttt agaaaaaagt gtgatccatt atgctagctg
    46921 tgccaaaaaa gcaggattag atggtgtggt ttcttctgct tgggaagtag aagcgatcaa
    46981 agaaatggca ggagacgaat ttgtttgctt aactccgggt ataagaccag aaggaacagt
    47041 cgcaggagat cagacaagag tagtcacacc ttctcaggca aaaaagatcg gctcaacttt
    47101 tatcgttata ggtcgaccaa tcactcagtc aactaatcct tataaagcat atcaaacgat
    47161 tcaaacagaa tggagctaac ctaaaatgaa tgttgaacaa agtatcgcaa aagacttatt
    47221 agaaattgaa gcagtatttt taaatccaag taatcctttt acatgggcaa gtggaatcaa
    47281 aagcccaatt tactgtgata accgaatcac gatgagctat ccaaaagtcc gaaaagagat
    47341 cgcaaaagga ttagcaagca aaatcaaaga agcttaccct gaagtacaag tgattgctgg
    47401 aactgcaaca gcaggaatcc ctcatgccgc atgggtagcg gaaatactgg atttgccaat
    47461 ggtctatatt cgaagtaagg cgaaagatca tgggaaaggt aaccaaatcg aaggacgtat
    47521 atttgaaggt cagaagatgg ttgtgatcga ggatttgatt tctacaggcg gaagtgtctt
    47581 ggaagcagct gaagcagcaa aaagagaagg tgcggatatc cttggtgttg cggctatctt
    47641 tacgtatgag ttgccaaaag gaaaagcaaa tttcgaaaaa gccgaaatcc ctcttatgac
    47701 gttgaccaat tattctgtat tgattgaagc agctttagaa gatcgttata tcgatgagca
    47761 agaattaact ctgctaaaag aatggaaaaa agatcctgaa aattggcaga tttaagcgcg
    47821 cttgatgaag atagagaaat ccgatttgtg tctccagaat catcaattgg aatagcaaaa
    47881 atccaaaaac tgattgcgag aagcatcttt tcatcaggta tgaaaagaaa cttctatcgt
    47941 gatcagtttt tgattttttt aaaattcatt tttctaagac tggttagcag aaagaagaga
    48001 ataatctctt ctcttttttc tattatatat agattttctc tattttttgg taagggagct
    48061 gtttcaaaaa tggtaaagag cggaaatgtt gcgaatatca gttatttaat gatatgatat
    48121 tcggaaaaag aaatctcaaa gggaggtaac ttttatgggg ttgaatgaat ttattttagg
    48181 attgaacaat ttagagacga tcacaagggc acctggattt tttaaatata cagagcatac
    48241 agttgcagca cattcgtatc gtgtagcatc tattgcgcaa gttctaggag acattgaaga
    48301 agcgaatgga caaccgatcg attggaaact gctctatgaa aaatcattga atcatgacta
    48361 cacagagcgt tttattggtg atatcaaaac gccggtgaaa tacgcaagca aagagttaag
    48421 agggatgctg caaacagttg aagaaaagat gacggacgaa ttcatcaacc aagagattcc
    48481 agctgagttc caagaagttt atcgccgtcg gttgttcgaa ggaaaagatg aaaccgtaga
    48541 aggagaacta ttagccattt cagataaggt tgaccttctt tatgaatctt ttgatgaaat
    48601 catcaaaaat aacccggaaa aagtttataa ggagatgttc attgaggcag tgactacgat
    48661 taaaagcttt gaacatcggc cttctgttca gtatttcttt aaagagatat ttccggaact
    48721 attgaaccag gaattttatg gaaaagaggc gtttttagaa accgtctcaa cgattgtaaa
    48781 gaaagaagaa aaataaaaat gatatgagat gcagggggaa gtatagttga aaaagaatat
    48841 ggatgtcgaa tggggctatt ctggagacaa aggtccggaa aattgggcga gtttatgtga
    48901 ttggtttgcg agaggtgcgg aatttccatt gcagtcgcct attcatttga ccaaggggga
    48961 agaaaccaaa atagaaggag acacgctttc ctttcattat caaaagcaac ggtttactga
    49021 caaggaattc aaaaacacga ttcatttagt accttttgac caactcagtt atgtagagtt
    49081 caagaaagaa cgctattatt tgacagatat tcatttccac ttgccttctg aacatatcat
    49141 caacggaaaa caggaagata ttgaatttca ttttgttcat atgaacagca aaaaagagaa
    49201 tctagttgtg ggtgtcatgt accagctaat ggtacaggaa ggttggctgt ataatcaaga
    49261 aaatggggaa agttggaact tagaaaaaca tgagcattgg gtaaatccgg atgtgttctt
    49321 tccggagcaa aaaagccatt tccattatat tggctcattg acaactccgc ctaccagcgg
    49381 gccaatccaa tggtttgtaa tggatcatgt aggaaaactg aaccaagagt ttcttctccc
    49441 cttcgatggt cagtatgctc gaccgaacaa ccgaccaatc cagcccttga atggaagaga
    49501 aatttattat ttcgaggagt ttgagcaatg aatattcagc agatgaaata cgtggtcgct
    49561 gtagcaaaca atggtagttt cagagaagcg gcaaagaaaa tgtttgtctc ccagccaagt
    49621 ctttcagctg gtatcaaaga attagaaacc gagttaggga tcacgctgtt tactcgaacg
    49681 aatcgagggg catatttaac agaagaaggg caagacttct taaatcgtgc cgagaaaata
    49741 ttggtccagc ttgatacatt agaaactcac tatctaacga gtgaaaagag agacaatttt
    49801 tcgatcgctg cccagcatta tgatttctta ggtcctttga ccgcacagct actcgaggaa
    49861 ttcaaagacg agatcaaaca atttcggatc atggagacga caacagcgag agtgatcgaa
    49921 gaagtcaaag agcagcacag tgagatcggc attatttata tgaatgagca taatcaagct
    49981 ggtatcagaa gatatttaca acaaggagag ctaagtggcc gcagcattgg aaaattcaaa
    50041 acgcatattt ttttaaggca aggacatcca ttagctgaac acgcagagat caccaaagaa
    50101 gaattgttat cttatcctca agttcgtttt acacaggatg gaaataattt cccgtatttt
    50161 tatgaagacc ttatcgagat ccctgatcaa gaaacagtga tttatacgag tgatcgaggt
    50221 actttgatga atatcgttct tgaaactgat gcttacgctt caggatctgg tattgtgatt
    50281 ggagggattc gcgagcactt gcggttaatc cctttggcag aaggcgaact aaatgaattt
    50341 tatatcattt attcggcgaa acgtccgctc agtgaaatcg ctcaaagatt tatcaaagag
    50401 cttactcggt tactggacca gcagagctaa gaaaagcaga tgagaacgct gtttattgaa
    50461 caccgttgat caaaaaagag gggttgtgac agaattttgt cacaactcct ctttttgtag
    50521 caaacaattt ataactaatt gctgttgtgg gaaagtacgc aaatatgatt ctagaaacac
    50581 tcattgatta cctgttttgt ttcatagctg taattttttc ttcttctggt gtcacgataa
    50641 tcgtcttttg gttttcataa ataacataac caggcttggc gccatttggt tttcggatat
    50701 gctttacctg tacaagatca accggcactt gggcagagta tcggtatttt gaaaaatagg
    50761 cagctaactc ggcagcttct gtaattgttt catctgaggg cttgtcactt ttaatgatga
    50821 cgtgcgaacc gggtatattt tttgcatgaa gccaatagtc ggttttttta gctgtcttca
    50881 ttgtcagctg gtcattttga agattgtttt taccaacaag aatgagcgtt ccgtcagaag
    50941 aaaagtattg atcaggctga gatggtttct tacgtttttg tttttttaag ttcttctttt
    51001 tcaggtatcc ttctgaagtc aattcttctt taattgcttc gatatccatt gggccggcaa
    51061 tttccagttg agataagaca gattcaagat attggatttc atctttggct tcttggattt
    51121 gttcgccaat cagcttaaca gcgttcttca gcttttggta tcgatggaaa tatttctgtg
    51181 cattttgatt tggtgtcaat gccggatcta gtgctatttt gattggccga tcttcttcat
    51241 aataattagg taaaacaact tcttttgcgc cgcgtggtac ttgtgtcaga aaagtagtaa
    51301 gtagttcgcc atttctacgg taattctcag cgttttcgga ttctttgagt gtttgttcac
    51361 gttttttcaa tttattttta tttcgtttta gttcattttc gatttttcga atcagttctc
    51421 cgccttgttg ttttgcccga tctttctctg ctttttcgtg ataatagcta tctaataatt
    51481 gactgagtgt tggataagct gttacagcag atgcctgttc ggacaatacc tgataagcaa
    51541 tcggtgtgaa aaaatcttta ttttccgttt cgtaaaaagt aggaataggc tgatggctga
    51601 tggctgagaa aaattcgtcc catacaacca tcttttcatt aggacgttcc agtaatcttt
    51661 tggtcagctc ttgagcgata tcgaaaccga ttccctgaaa ctgacgttgg attgcttttg
    51721 gatctagttc agtttgggaa agccgctgaa agattttttc tttctcggag ctaaatgggt
    51781 tcaagacctc ttgttttggc ggagcaacat attctacacc aggaagcaaa gaacgataag
    51841 tgttttgaga gcttccaatg tgtttgatcg catccagtat ttttccagtt tctcgattaa
    51901 ctaagacgat cgtactatga cgtcccatta attcaacgat caatatgata ttttgtagat
    51961 cacccaactc gtttcgttta gcaaagtgga aatggatcac tcgatcattt tcgatttgtt
    52021 cgatgtcttc taaaatagcg ccatccaaat attttcgaag catcatcacg aagttaggcg
    52081 gattatcagg attctgataa tcgatttggg taatctgtac acgagcataa cttgggtgcg
    52141 cagataataa taatcgatgg tttttgccgc gtgaacgaat caccagcacg atttcatttt
    52201 cataaggctg atggattttc gagatccggc cagatagtaa cgtttcacgc aattcgttga
    52261 ccatcgcgtg ggtaaataca ccatcaaagg acatggttca ttcctcattt cttttcataa
    52321 gtatattcat tataacgaaa aaaagaagaa aaaccaattt ggccgaatag taaagcaaaa
    52381 gtctagaaaa atcttggact aattacataa aaaacagtgt ttctatcgtt gaaatccaaa
    52441 tttttaggta
//
LOCUS       DAXLPQ010000011        52237 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.011, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000011 DAXLPQ010000000
VERSION     DAXLPQ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.011"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(34..870)
                     /gene="pheA"
                     /locus_tag="ACF3UO_000898"
     CDS             complement(34..870)
                     /gene="pheA"
                     /locus_tag="ACF3UO_000898"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFD3656943.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(867..1376)
                     /locus_tag="ACF3UO_000899"
     CDS             complement(867..1376)
                     /locus_tag="ACF3UO_000899"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFD3656944.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(1369..2664)
                     /gene="aroA"
                     /locus_tag="ACF3UO_000900"
     CDS             complement(1369..2664)
                     /gene="aroA"
                     /locus_tag="ACF3UO_000900"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFD3656945.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREIGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(2677..3768)
                     /locus_tag="ACF3UO_000901"
     CDS             complement(2677..3768)
                     /locus_tag="ACF3UO_000901"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFD3656946.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(3785..4951)
                     /gene="aroC"
                     /locus_tag="ACF3UO_000902"
     CDS             complement(3785..4951)
                     /gene="aroC"
                     /locus_tag="ACF3UO_000902"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFD3656947.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(4953..6017)
                     /gene="aroB"
                     /locus_tag="ACF3UO_000903"
     CDS             complement(4953..6017)
                     /gene="aroB"
                     /locus_tag="ACF3UO_000903"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFD3656948.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(6050..7072)
                     /gene="aroF"
                     /locus_tag="ACF3UO_000904"
     CDS             complement(6050..7072)
                     /gene="aroF"
                     /locus_tag="ACF3UO_000904"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFD3656949.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(7731..8705)
                     /locus_tag="ACF3UO_000905"
     CDS             complement(7731..8705)
                     /locus_tag="ACF3UO_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFD3656950.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(8686..10569)
                     /locus_tag="ACF3UO_000906"
     CDS             complement(8686..10569)
                     /locus_tag="ACF3UO_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFD3656951.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(10587..12812)
                     /locus_tag="ACF3UO_000907"
     CDS             complement(10587..12812)
                     /locus_tag="ACF3UO_000907"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3656952.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            12927..13961
                     /locus_tag="ACF3UO_000908"
     CDS             12927..13961
                     /locus_tag="ACF3UO_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3656953.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(14028..15041)
                     /locus_tag="ACF3UO_000909"
     CDS             complement(14028..15041)
                     /locus_tag="ACF3UO_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3656954.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(15119..15307)
                     /locus_tag="ACF3UO_000910"
     CDS             complement(15119..15307)
                     /locus_tag="ACF3UO_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFD3656955.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(15747..15875)
                     /locus_tag="ACF3UO_000911"
     CDS             complement(15747..15875)
                     /locus_tag="ACF3UO_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFD3656956.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(15878..17251)
                     /gene="rlmD"
                     /locus_tag="ACF3UO_000912"
     CDS             complement(15878..17251)
                     /gene="rlmD"
                     /locus_tag="ACF3UO_000912"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD3656957.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(17362..18417)
                     /locus_tag="ACF3UO_000913"
     CDS             complement(17362..18417)
                     /locus_tag="ACF3UO_000913"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFD3656958.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHADDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(18427..19857)
                     /gene="gatB"
                     /locus_tag="ACF3UO_000914"
     CDS             complement(18427..19857)
                     /gene="gatB"
                     /locus_tag="ACF3UO_000914"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFD3656959.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(19854..21326)
                     /gene="gatA"
                     /locus_tag="ACF3UO_000915"
     CDS             complement(19854..21326)
                     /gene="gatA"
                     /locus_tag="ACF3UO_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFD3656960.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(21326..21631)
                     /gene="gatC"
                     /locus_tag="ACF3UO_000916"
     CDS             complement(21326..21631)
                     /gene="gatC"
                     /locus_tag="ACF3UO_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFD3656961.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(21737..23773)
                     /gene="ligA"
                     /locus_tag="ACF3UO_000917"
     CDS             complement(21737..23773)
                     /gene="ligA"
                     /locus_tag="ACF3UO_000917"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFD3656962.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(23790..26024)
                     /gene="pcrA"
                     /locus_tag="ACF3UO_000918"
     CDS             complement(23790..26024)
                     /gene="pcrA"
                     /locus_tag="ACF3UO_000918"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFD3656963.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            26179..27738
                     /locus_tag="ACF3UO_000919"
     CDS             26179..27738
                     /locus_tag="ACF3UO_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFD3656964.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(27848..29779)
                     /locus_tag="ACF3UO_000920"
     CDS             complement(27848..29779)
                     /locus_tag="ACF3UO_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD3656965.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(29797..30711)
                     /gene="pfkB"
                     /locus_tag="ACF3UO_000921"
     CDS             complement(29797..30711)
                     /gene="pfkB"
                     /locus_tag="ACF3UO_000921"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFD3656966.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(30708..31460)
                     /locus_tag="ACF3UO_000922"
     CDS             complement(30708..31460)
                     /locus_tag="ACF3UO_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3656967.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(31621..31830)
                     /locus_tag="ACF3UO_000923"
     CDS             complement(31621..31830)
                     /locus_tag="ACF3UO_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656968.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(31841..33169)
                     /locus_tag="ACF3UO_000924"
     CDS             complement(31841..33169)
                     /locus_tag="ACF3UO_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656969.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            33305..33460
                     /locus_tag="ACF3UO_000925"
     CDS             33305..33460
                     /locus_tag="ACF3UO_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFD3656970.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(33534..34121)
                     /gene="yihA"
                     /locus_tag="ACF3UO_000926"
     CDS             complement(33534..34121)
                     /gene="yihA"
                     /locus_tag="ACF3UO_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFD3656971.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(34204..35454)
                     /gene="clpX"
                     /locus_tag="ACF3UO_000927"
     CDS             complement(34204..35454)
                     /gene="clpX"
                     /locus_tag="ACF3UO_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFD3656972.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(35701..36990)
                     /gene="tig"
                     /locus_tag="ACF3UO_000928"
     CDS             complement(35701..36990)
                     /gene="tig"
                     /locus_tag="ACF3UO_000928"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFD3656973.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(37144..38076)
                     /locus_tag="ACF3UO_000929"
     CDS             complement(37144..38076)
                     /locus_tag="ACF3UO_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656974.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(38233..38892)
                     /locus_tag="ACF3UO_000930"
     CDS             complement(38233..38892)
                     /locus_tag="ACF3UO_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFD3656975.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(38895..39920)
                     /gene="sppA"
                     /locus_tag="ACF3UO_000931"
     CDS             complement(38895..39920)
                     /gene="sppA"
                     /locus_tag="ACF3UO_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFD3656976.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(39933..40223)
                     /locus_tag="ACF3UO_000932"
     CDS             complement(39933..40223)
                     /locus_tag="ACF3UO_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656977.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            40632..42437
                     /gene="glmS"
                     /locus_tag="ACF3UO_000933"
     CDS             40632..42437
                     /gene="glmS"
                     /locus_tag="ACF3UO_000933"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFD3656978.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(42509..43864)
                     /gene="glmM"
                     /locus_tag="ACF3UO_000934"
     CDS             complement(42509..43864)
                     /gene="glmM"
                     /locus_tag="ACF3UO_000934"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFD3656979.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(43888..45057)
                     /locus_tag="ACF3UO_000935"
     CDS             complement(43888..45057)
                     /locus_tag="ACF3UO_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFD3656980.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(45054..45941)
                     /gene="cdaA"
                     /locus_tag="ACF3UO_000936"
     CDS             complement(45054..45941)
                     /gene="cdaA"
                     /locus_tag="ACF3UO_000936"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFD3656981.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(46130..49822)
                     /gene="nifJ"
                     /locus_tag="ACF3UO_000937"
     CDS             complement(46130..49822)
                     /gene="nifJ"
                     /locus_tag="ACF3UO_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFD3656982.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLHHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLNLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            50021..50542
                     /locus_tag="ACF3UO_000938"
     CDS             50021..50542
                     /locus_tag="ACF3UO_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFD3656983.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(51241..51798)
                     /locus_tag="ACF3UO_000939"
     CDS             complement(51241..51798)
                     /locus_tag="ACF3UO_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656984.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(51977..>52237)
                     /locus_tag="ACF3UO_000940"
     CDS             complement(51977..>52237)
                     /locus_tag="ACF3UO_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3656985.1"
                     /translation="DLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDFI
                     LGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
BASE COUNT        14124 a        11385 c         9406 g        17322 t
ORIGIN      
        1 taagttaaat aaatcaatca gtattcttga ctttcatcta cgcgtctctt ctactgtcag
       61 cactggataa cagcccaata tttgactttc tcctccgagc atcttgattt cttggagcgc
      121 attctctact aatgtcattg gacggtccaa caacaaatcg atcacgaaaa aatattctcc
      181 caagctagtt ttcaatggtc gggattcaat cttacttaag ttgatttccc gccagccaaa
      241 agctgccagc attttatgaa gcatccctgg ccgattagca ggtagtgtca agatgacact
      301 catttttact ggagctgact gctggctggt catctttcgg tcaccgacga tccaaaaacg
      361 tgtctggttc aactcattat cttggatatt ctcagctaag atctccaatc caacatgctg
      421 tgctgtttct aatgaagcaa tcgctgctgc gtcttctttc ggatgttctg ctacatacat
      481 tgctgcagca gttgttgatt ctgttgctac taaaggaaca ttaggataat gcgtttctaa
      541 aaactgttgt gattgtgcta gtgcttgtgg atgtgaaagg atttttgtaa tctttgttgc
      601 tggattgcct aaaagctgct gcttgatagg aagaacgatt tcacttttaa cttcgacttc
      661 tggatgtttg gaaagaagat cgattgtgtg atgaacagct ccttccaatg aattctctac
      721 aggaacgaca gccagatcga cttgtttgcg aaacaaagcg cgcaaacaaa cagggatgga
      781 agcatacgca gtcaattgtt ctgtaggaaa tagctgacaa gccgcctgat aagtgaatga
      841 actttctggc cctagatagc tgacgttcat atgcttttga tcctttctat aatggtatcg
      901 atgatctttt ctggtgtttg attggtcgtg ttgattcgat gtgtcgcact ttcttcatac
      961 caagaaagtc gttgtgccaa taatgctttt atttcttctc ttgtttttcc aagagctaaa
     1021 ggtcgaatag acgtttcatc ttgttggata cgatcaacta gacagtccgc ttctgcctct
     1081 aagtaaagaa caatcggctg tgtttttaaa aaacgccgat tttctgcact ttggacaatc
     1141 cctccaccag tcgcgataat tttgtcttca tttgacagct ttcttaaaat atctgactcc
     1201 acttttcgaa agcttttttc accgtaatag tgaaaatatt cggcaatcga caattggata
     1261 tgttcctcaa tctttgtatc taaatctaca tactcttttt gtaaacattg agctaaccct
     1321 ttaccgattg ttgtttttcc agcgcccatg aaaccaatca gcaaaatgct agccatgagc
     1381 ttctcctcct gacacaagtt ctgctaaatc gtcaaaaaat gccggataag agattgaaac
     1441 agcttcagct ccttctagtt cgcaaggtcc atcagctatc aaagcagcta cttgcagcat
     1501 cataccgatt cgatgatcgc ctctgctgga cacttttgcg ccatgcagag gtgtcggccc
     1561 atggatgatc agaccgtctg ctgtcgcttt tatctttgct cccattttct gtaattcttc
     1621 tgccaccgca tcaattctgt tggtttcttt tacttttaat tcttctgcgt ctttgatgat
     1681 cgtgattcct tctgcttgag tagccactaa agctagaatg ggcaattcat caatcagacg
     1741 cggaatgatt tctccaccaa tcgttgcttt cttcaaatga ctcgtcttga cacttaaatc
     1801 agccgattgg ttctgttcat tgtgattcgt ctgggtaatc gctgcgccca tctcctccaa
     1861 cacatctaag ataccagttc ttgttggatt gaccccgaca ttttttaaca acagttggct
     1921 ttccggaaca agaagtcctg ctgctagaaa gaaagcagct gatgaaatat cacctggaac
     1981 agttatctgt tgaccagtta atttttgcgg tccggtcact atgatcgttt tatcttccac
     2041 tgtgatcctt ccgccaaatt gacgaatcat ttcttccgta tggttacggg aacgttcttt
     2101 ttcaacgatt acggatgtgc cttctgcttg taatgccgca aacagcaaag cagatttgac
     2161 ttgcgcactg gctacaggca tattgtatcg gataggtgat aaagagcggg ttcctgtcac
     2221 agtgattggt agatactggt cattttcttc tccttgcaag tcagcgccga tctcgcgtaa
     2281 aggttccatc actcgcccca ttggacgttt agacaacgaa gcatccccga acagagtagt
     2341 cgtaaaaggc tgtccagcca aaatacccat caataaacgt atggtcgtac cggagtttcc
     2401 catgtcaatt gattcggttg gttggacaaa tgagtggcta ccgcgaccat gaatcttgat
     2461 cacctcttcc tcttcttcga tctcgacacc taattgttgg aaggcatgta aagtactcag
     2521 acaatcttct gcgcgcaaaa aattttgtat agtcgtcgtt ccttcagcaa ttgctccaaa
     2581 catgatgctg cgatgggaaa ttgatttatc tgctggtatc ctaacagtcc ctcttaatcc
     2641 atgtatttgt tgtaataatt gcatttatcc agcctcctat ttgatccagc aatgataact
     2701 ggtattagac ataatgattc tttttgcttg taacaaatcc tgttggtttt taaaactgat
     2761 ttgcagtatt cctaaaatat cttccctggt ctcttggatc ttcaaattaa tcaaagaaac
     2821 tcccgctttt ccgatcagtc cagttacttc tgcaataacg ccaggttcat ctggcacatc
     2881 gataaataaa tcaaaaaagg caggaatcgc gccttgctta tggacaggca actggtctcg
     2941 actttctttt gcccgattga aaaaagaaaa gatttccgat tggttctcag tcatgatcca
     3001 ttctgctatt tgtgtcattt cttgttgcca atctgccaat cgttccaata atatctgctt
     3061 attgctcaac aaaatatctg tccacatgac aggatctgag gaagcgatcc tagtgatatc
     3121 tcgaaagcct cctgctgcca gttgtttggc tcgcggatac tcttgattga attgttctgc
     3181 ctgattgact aagccagctg ccagaatatg tggaaaatga cttagcattc ctgttatacg
     3241 gtcatgttct cttgctgtaa gagttacata ttttgctttg gttccgcaaa atagttcttg
     3301 cagtttttca acatcttttt tcgtcttttc caaaggtgta aagatgtaat aggcattttc
     3361 aaatagttta gcatctgctg cctgtatacc tgatttatga gaaccagcca ttggatgtcc
     3421 accgacaaac cgaagatttt tctgctcagc ggatgtcacg acttgctgct tcgtactgct
     3481 gacatccgta atgatgacgt gatcagacaa gttgattctt tcaaggacat caagataagc
     3541 taaggttgta cggacgggaa cggctaataa gataacgtct gcttgttctg cacctgtttc
     3601 aaaatcactt gcaacgtaat caacgatctg ctgttctact gcttgctcac gggtttttga
     3661 ctgactatcc caaccaacta ctatcagttc tggattggtc tgacgaatac aaagtgccat
     3721 agaagcacca atcagtccaa gccccacgat aaaaacatgt tgtgccatct tatttgcccc
     3781 ctttttagta atgtttcaag tagtcacggt actccttcac tgcagctttc aactcaacaa
     3841 gcgaatcact tgggaatttt gacaatagct ctgtcgctac cacagtggct acaacatttt
     3901 ccgcaacgac gctagctgca ggaactgctg tactatccga acgttctaca cttgctttgt
     3961 aaggttcttt tgtatcgata tcaacacttt gaagtggctt gtacaatgta ggaatgggtt
     4021 tcatgacccc gcgaatgaca agtggttcgc cattggtcat tccgccttcg aagccgccta
     4081 gattattggt acgtcggaaa tagcctcttt cttcttccca taggatctca tccatcactt
     4141 ctgagcctgg taatgaacca gaagtgaatc cgaccccaaa ttctacgcct ttaaaggcat
     4201 tgatactaac cacagcttgt gcgattttgg catctagctt cgtgtcccat tgtacgtagc
     4261 ttcctaatcc agctggaacg cctccaacga gcacttctac aattcctccg atcgtatctc
     4321 catttttctt tgtctgatcg atcaaatctt ttattctttg ctcaactgct ggatcaacaa
     4381 ctcgtacttc tgacgcttca gaaatttctt tgatttcttg aatcgagata tttccaggta
     4441 tttctgcttg gattccacca agacaaatca cgtgtcctgc tacgatgatg tcaagttctt
     4501 ccagaatttt cttggcaatt gcgccgattg ctacacgcat ggtcgtctct cttgcagagg
     4561 accgttcaag cacattccga agatctcgat gatggtattt cataccgcct accaaatccg
     4621 cgtgtcctgg acgcggacgt gcaactcgcc gcagtgattg gtctttttca ggcacttctg
     4681 ctacagacat gacagttgtc caatttttcc aatctttatt ttctaccact aaagtgacag
     4741 gtgaaccaat tgttttgccg tgacggatgc cagacgtgat ccgaacacga tctttttcga
     4801 tcttcatcct tcctcctctg ccgtaaccag cttgtctgcg agcgagttcg tgattgattt
     4861 cttcttctga cagaggtaat cctgctggta gtccttcaat aatggctgtt aattctggtc
     4921 catgggattc tcccgcagtc atataacgca tcttacagtc ctcctaagta atctttgaat
     4981 gtctctgtgg gaacaggaac gatttttgct tgcccaatct tttctagcaa gatgatattc
     5041 aattggcttc ctcttgcttt cttatcatgg gttatcgcgt ggaataattc atctggatga
     5101 cttagatcgt acgtaatcgg cagatggaat ttttgaagta tcctttctaa agcagctgtc
     5161 gatccagttg gagacaagcc gattttttct gcatgagaag tgatggctac cattccaata
     5221 gctactcctt ctccatgact gactacccca tatcctgctg tattttcaat tgcatggcca
     5281 attgtatgac caaaatttaa aataagtcga tttccttggt caaagacatc ttcttccact
     5341 acttttcgtt tgatttccaa cgtagcagta atgattggaa cagcatgttc cagaagatct
     5401 ttttcgtctt tcagctcgtt cagctgtttc caaagcgttg catctgctat agctgctgat
     5461 ttgatgattt cagcgattcc ttctcgtaaa cgacgtaccg gcaaagtttt tagaacctca
     5521 ggatcaatca atacaccagc tggctggcta aatgttccga caaggttttt cgctttgttt
     5581 gtattgactg ctgtcttccc gccaatacta gaatctactt gtgcaagtag cgtagtcgga
     5641 atttgaacga aatggatccc acgcatgaac gtcgaggcca cgaatgctgc tagatcaccc
     5701 accattcctc caccaagtgc aagtatccca tcgctgcggg taaaatcatt atctgctaaa
     5761 aaatcgtata actcagctgc ttgttctaaa gatttactgg tctcacccgc cggtacgatt
     5821 gaaaggactg gttcaaaatt agcttgtctc aattggaaca tgattttttc tgcatatagt
     5881 ggagcaacgt ttgtatcagt gatcacagct actttttgag gtctccaaat cgtttgaagc
     5941 catgatccag cctgttctag tgcgcctttt tcaatatgaa tatcgtattt ttggttatca
     6001 acatgtacag taagcattcg tttcacttct ttcttttaaa aagctggaat taatcgagtg
     6061 tctgaatctt ttccattgct tctttcatga tcgcaacttc tttcatcatg cgtgagtaag
     6121 tcttttcatt caacgattgg ggaccgtctg accaagcatt tgcaggatca ggatggatct
     6181 ctacgatcat gccatctgct ccgcttgcca cacccgcacg agccattggt ggtacaagtt
     6241 cccaaattcc tgtaccatga cttggatcaa caatcacagg gaaatgagtt aattttttca
     6301 tcaatgggac agcacttaaa tcaaacgtat tacgtgtcgc tgtttcgtaa gtccgaatcc
     6361 cacgttcgat aaaaatgaca ggagatttgt cttcgactgc aatgtattct gcagcattaa
     6421 gccattcatt gatcgtaccg gaaattccac gtttcaatcc aacaggttta cctgttttac
     6481 cgacagcaga tagcagttta aaattttgca tattacgtgc gccaatctgt aggatatcgc
     6541 tgtactcagc caccatatcg atatgccctt catccatcac ttcagtaatc actttcattc
     6601 caaattcatc agccgcttga cggatgtatt tcaatccttc ttcttctaaa ccttggaaag
     6661 catatggaga agtacgtggt ttgaaggcac cacctcgcag aatttttgcg cccccggctt
     6721 tggccattcg cgcacattct ctgatttggt ctaatccttc gatagaacaa ggaccagcca
     6781 tcgtcacgaa actgccgtca ccaattttta ctccgtctac atccacgact gtattgccag
     6841 gatggaattc tcgagaagtc aatttgtatg tgtttaaaat acgcacagca ttttctactc
     6901 cttcatagcg tgtaaatgct ccttcttgta aacttcgcgt atcacctttt agtccaatca
     6961 ctactcgttc tgttccttga tcgattgaga ctttgaatcc ttctttttcg atatgatcga
     7021 cgactttttt tatttgttct tccgttgctt cttttttcat aattactatc attgtttttc
     7081 ccgctttctt ttgtttactt atctatcttg gctgattttc tctacttttt caaggtggtt
     7141 ttacattaat tcctactaaa tgaccgtgtc ctgttgttct cattttcgct ccttctttcc
     7201 tacttatgac ccagataatc aacaaaaaaa gatgtccctg taggaaattg cctctacagt
     7261 gaacatcttc aacgagcctt aaaaagcgct gcaaaaatat aaaatagcca ctatagatga
     7321 atttctctac gtggctgtaa gtcgtgttta aaaatcttta gccatcatag atacaaacct
     7381 ggtttgtttg tacccacgaa gtcatgaata caaacctatc taaaatagct aaagtaatac
     7441 gtattcagtt ttgtaagttt tctagatttc ataaaaaatc gctccaaact gatgtaagaa
     7501 ttgtacctag tatagacata aaaaaatcga ctgtcaatca tttttatgaa acttttttta
     7561 attttctgat agttaacttt gtttttcaga aaaataacaa ttggttttat tgaagaaaat
     7621 agtcatgaac aaaagtatct gagaactttt ttactctctt gttcatgaca tatagaataa
     7681 agcagctttg tcttgtaaac tccgtttttc aaataataat ctaaagattg ctactgaata
     7741 ataaagccga tttcatggtc ctcttcgctg ctgattcggt aaggtgactc aacatccgct
     7801 ccccagctat tgataccccc gactcctctt acttttgcaa aaatcgtaag aaccgttcgt
     7861 ctttctggcg gtagttcttc tatatgtgtt gcctgttcca gttcttctgc tttgaatggt
     7921 aaagcggaaa aagcaaatgg cgtatcctgc tgttcaaatc gcaacgaaaa atcttcttga
     7981 tctttatccg tattatccaa cgtttgattt cttgttagtt ctacccattt cgtttccata
     8041 tgcatgccgc attcttgggg aacaaggtat ggggaaacgg ggagtcctgc cactttataa
     8101 ataccttcga caccaccagc catccgatcc ggatatgttt cccctgatag gccttcatac
     8161 tcaaaaaatt ttgctttcgt tggcataatg aaccttaaac ccaatgcggg taattccggt
     8221 aatccttttt gtccataata atgcatattg acaagcattt taccctctcc agcgatttgg
     8281 taggaaattg tcacttgggt ttttggtact gtgttgattt ccagtgtaaa aatgatttca
     8341 accgtttcag cgtattcatt acttgaatat tgattattta ctggagcaat cggcaaatcg
     8401 atctttttat tgtccaccag tacttctatt tctttgactt ttggatacaa tccggctcct
     8461 aaccacatac cggatttaaa tccaaatccg ctacctctgt cattatcggt cgttgctcgc
     8521 caaaaaactg gaagtgtttc ccggtatagc cattcttttc cgtttttatt gagcgattcc
     8581 agtccgcctc ttgtataaga aaaaatataa tgcgtattcc ccgatttgac acctaatgta
     8641 cagtcgccga agacgattgc aactttttcc gtatccatat gacttttatt tactgtattt
     8701 ttcataataa tatcttacct cctgcatggc gggtttttct tgtccatctg caaaaacgat
     8761 cccattccct gagaattcat agtcacttgg tttatcgtca aagtcaccgc catagcgcat
     8821 cacttctctg cctgtgattg gatcagtcac ttggatcgcc tgatctttaa aatcccatat
     8881 atagcctcct tggtacattt cataacgatc aagcaacgtc atgtaagaat ccattccacc
     8941 taacgaattc cccatgtcat gcatatattc acataagatg aacggttttt ccgctttatt
     9001 ttcaaggtag tcaatgatct cttctggtgg cgcatacatg cagcttttta catctgaaat
     9061 cgaatcttcg aatgctggat ttggaaaatt cccttcataa tggacaagtc gatcggggtc
     9121 tacttttttg aagtaatcgt tcatttgtcg aatgttttct tccgcataag attcatttcc
     9181 aagagaccaa aaaagaatac ttggatggtt ttttaatgtt tcgaaattcg tttttgctcg
     9241 atcaagaaca gccgcctgcc actgaggtac tgcacctggt acgttgtaag aaggctcaaa
     9301 tgcgcccatt ttttgccatg agccatggga ttcgaggttc gtttccgcca tcacatggat
     9361 tcctgcttgg tcgcataaat aataccaagt gatctggttg gggtaatgag atgtccgtac
     9421 gccgttgatc tttgcatttt ttatgatagc caaatctttt tccatatctt ctatagtgat
     9481 ggcgcgtcct tttttcggat gccactcatg tcgatttacc ccgttgataa tcatccgttt
     9541 tccattgaag tagatgattt tatctttgat ttcgatttta cgaaaaccga aggaatagtc
     9601 aatatactcc gttactcttt tttcttcgtc tatcgtctcc aattcaagct tatataaatt
     9661 gggctgaaaa tgcccccaca gtgccacatt ttcaaatcca tcgatgcgaa tcgtcatttg
     9721 ctcttttaac ggatattgct gttgatagat ttccttccca tcaggatcta gtatcgctac
     9781 attcagctga ctgtttttgg ctacttgctc aaaagacaaa tctacttcaa gtttgccatt
     9841 ttgacatttg tcatctaagc gaggtttgat ccaaagatct tctaaatggt tttgtcctcg
     9901 agcaactaag aagacatctc tgaagatccc aaaaaatcgg aaaaagtcct gatcttccaa
     9961 gaatgcagct gtacttcttt tgtaaacctc cacagctaga atattttctt cttccaaata
    10021 aggtgttaaa tcaaattcag acggagtgaa cgaatcttcg gcatacccga taaaatgacc
    10081 attcaaccaa ataaacattg cttgttctac accagcaaaa tgaatcgaga tttgttttcc
    10141 ctttagacct tcttctaatc gaaaagtcgt caaatacgaa ccaaccggat tgtctttagc
    10201 agctgaaaag atcccttccg cctctttctc agggcttgtc gtgaaagggg gacggcgaaa
    10261 tacatgtccc tcccacggat acatcgtatt gatgtaatgg atcttgtcat aatttgctaa
    10321 ttcaatatga ctaggaacag tgatttcatc aaaagaacag gcatcaaaat cttttttata
    10381 aaatgttttt ggtcgtaccg aaggatttgg cgaataacaa aaacgccatg atccatttaa
    10441 agactgttta agggaggatg tggtttctac ttcttccctt gttgcataac aaacatgatc
    10501 gctatgtgca tttgattggt tcactctaaa aacttgtgga tcatctaacc attttatatt
    10561 tgctttcata cttttttcct tctctctcat aactttttga aatgaagcag ttctgtttgg
    10621 aaatcacctt gaaaatcggg gaagtaaagt ccaactgtca tcaattcggc ccccgaaaat
    10681 atccgcttcg aggtctgttc ctgataaagt gcctcatcat ctaaccccat cagatatact
    10741 tcatggaacg ctggttgagc tgaagctagt atcctcccta aaaacacaat agcttcatct
    10801 tgtttaggag acacaaacat ccatgcggca atattttctt caaaaggact cgccaaacga
    10861 taataatggc catactggat caccggacga atcgtttgat aggatataat ttggtctttt
    10921 acttgctttt cttcttcagg agacagcttt gtcaaatcca gttcataacc aaaaacagcg
    10981 ctcatagctg tttctcctct tgttttcaac gaagtagatc tgtcggtctg atgatttggt
    11041 acagctgata catgagctgt gatggacgaa atcggataag caaggcttgt tccatattgg
    11101 attttcatac gctccactgc atccgtgtta tcacttgtcc atgactgcgg catataataa
    11161 ataaacccgg catcaaaccg tccacctcca ccagaacagc cttcccataa gatttccgga
    11221 taatcagttg tcaaatgttc aagtagttca taaagcccga gcatataacg atgcgctact
    11281 tctccttgtc tctgtgggtc aagggtaatc gaatagacat ctgaaagcga acggttcata
    11341 tcccatttga tgtagtcaag aggaatcgta tctaaaatct ttctcatttg tttctcaatc
    11401 gtctgccgaa catctaacct tgtaaaatcc agtacatgtt gtgatctgga agcagaaggc
    11461 attctacctg gctcctgcat aagaaaatca ggatgtgttc gatacagttc agaatcaacc
    11521 gagatcattt caggttcaaa ccataaacca aatttcaatc ctttgctatg agcataatct
    11581 gctatttcac gtaatccatt tgtcaacttg ccttcatact cgaaccagtc tcctaatgaa
    11641 gaattgtccg catctctttt tccaaaccag ccatcatcta atacgaacat ttcgatgcct
    11701 agctcctttg cttcatcaat gatcgccttg attttttcac tattgaagtc aaagtaagtg
    11761 gcttcccagt tattgaccag aatcggccgt tcagcaaatt gatgacgacc tcttgcgatt
    11821 ctttcacgta gcaactcatg gtggatctga ctcattttgt tcaatccctg acttgagtaa
    11881 gaaaggatca tttcaggtgt ttgaaaagac tggcctgcat tcaattccca cgaaaaacga
    11941 tggctgttga tcccaccgac gactctcaat tgattgatct gatctttttc aagttcgaaa
    12001 gaatggttgc cggaataaac aaattgaagt ccgatcgctt ctccagtatt ttctgtcgta
    12061 tgatgatgaa ctaaagcaat aaagttattc atatggtgac tgctcgttcc tcgacggctt
    12121 tcaaatactt ttgttccaga taaaacagat tgccgtgaaa tctgtctttc attgacatgt
    12181 gctcctggca aagcaatgac ttcatcaaat cgcctagtat gggcaaagtc tagctggaaa
    12241 ctagccgctt tttctagttt gattgtttct ccggtttcat ttcttatctt tacagatcgt
    12301 gtgatcactg ctctatcagt aaatatggta tagaacaaat cgaaataaat cgctgtttct
    12361 ctatccttaa gtgaaatcac caacgtttgt gcctctgact tgtccatcac ataagtttga
    12421 ggcaagcctt cgatctctgg cttcccatct gtaatataat ggctgtcata tctcagatcc
    12481 agtaagtctg atccattctt gcgctgaatg atcgatgcgg gcgttcgaaa gtccatgctg
    12541 ccatgagaag agtattcttg cggtagtgta tctttcgaca gagaccggtc aggatttaag
    12601 ggaacatttc ctgaaaatcc acgatctctt cggggataat ttttattgtc tttgtactgc
    12661 ttgactggtt tgccaaaata aatatgcgcc aatacattgc tttcttctat ctttatcaga
    12721 taagaaagaa atgtatttcg taaatggaag actcggctct tttcatcaaa taagatgaaa
    12781 tttttatctg tttttctatg cgtaatatcc atcatttcac tcccaacaaa acggaaaccg
    12841 tttacttttt tttataattc ctgtatactg tttactaaac aattttgtca ataaaaattt
    12901 tttatttttt tgaggagtgt gtaaaaatgg ttggaattag agatgtcgca cgaaaggcaa
    12961 atgtctctcc tgctacagtt tcccgtgtgt tgaataacga tcagacgatc catgtggctc
    13021 agactactcg gcaacggata gtagaggcag ctgctgcgtt ggattatgac atcagtactc
    13081 gtaaatatat caaaaagaga atgccttcga ttggtgtgat ctctacgatc ggcaaagcga
    13141 gcgaagaaca ggatatctat tacaaacatt tgcgagtagg gatggaagaa gaagctcgac
    13201 gtctgcattt agggatgaat cgaatctata atctatctga taatcctaaa caatgggaag
    13261 atctagatca gttaggtgcg gtgatcgttg ttgggactgt tacgaaagaa tcgattaccg
    13321 ccttgttaaa acaaaacatg caaatagtcg tcgtggataa ccctgacatc cagcaagagg
    13381 tcgatatggt gtatgcagat cttgaacgga tgactaaaac cgtactggaa ttgttcttag
    13441 aaaatggtca taaaagaata gcctatatcg ggggatataa agtcgatatg gatgaattcg
    13501 gtgggaagca gatttctata aatgaaaaga ggatgcgtgc ctatcagcat tttatgatcg
    13561 atcatcactt agaaaaatat atgtcttatc atctaggtgg ctggacagaa aaacaaggtg
    13621 aggtacttgc gactaatcta ttagaaaatg aatcccctct tcctactgcc attcttgtcg
    13681 ggagcgatcc aatggcaatt ggtgtctatc gggcattgaa acaaaaaaat atccaaattg
    13741 gagaagagat tgttgtagca agctttgata atatcgagac aatcgcaaac ctctcccctg
    13801 gcttgaccag tgttcaaatc aatgcgaaat caattgggca agcagctgtt cgaatggcat
    13861 tggagcgaat tgacggtata cgggacgaac caatcatttt gacttatcct gcacgattga
    13921 ttgttaggga aagttttatc ccaagaacaa aaaggtattg aaagagaggt tgtgaaaagc
    13981 cgcttcgttt cttcatactc aaaacgaaac ggctttttca caacctctta cttatactta
    14041 ttcacaaaat ccaatgtctg ctggtaacaa ttttgcgatt cttttagcgt gtaatcaaat
    14101 tggtattcat gggtaatctc tttttttgta tctgtataaa acaaggattg cacgggtacc
    14161 tttaattctg tcaaccgatt ttctaatgct tgaccttgct cctggaatga gtatgcattt
    14221 ccgtcagtta tatacgttgg cggaaattcc ttagaaacat ggtcagccac actagcttct
    14281 ttcaattgct cactcgtttt ccaatctttt gttccaatca acgaccacgc aacggttttg
    14341 acgaaaaact tcataaatcg atcatccgaa tgctgctgtg ctgttagctt caaatcaaca
    14401 ggtccgcaat aagaaatggt tcctttcaga ctatcttttg gaagtagatg tttgattttc
    14461 atttgtttag catacgcatc attcgtttgt atagctgcat attgcaatgc gatttgtgaa
    14521 cctgcactat ctccaccaaa aaataattgt tccatgtcta gcaatttgtc gtctttttct
    14581 tcagctaata aatctttgat cagttcattc acttgaagaa cttgattagg gtattctgaa
    14641 tcaggcgcta attcataatt catcgcaacc actgcgatgt tggcgtctga aactaatttt
    14701 gtcgcaaatt ctttgacacc cgatttatct ccgccgacga atcctccacc atgtacccaa
    14761 aatagaacag gaacaggccc cttgctgttt tttggatagt agatgtcata agtattctct
    14821 ttatacttgg actcatacgt caaatctgtt tttttcgcca cgtttttttc tgcttgatcg
    14881 aacgtttttt tatcagtgat ttgaacagta tttgaaaaca tatggttgat caagaatgct
    14941 ccaggtctgg gggaaagctg gaaggcaaga aagattgcaa acgcgatccc aagaatgatt
    15001 ccgaagaacc atccgataaa tttaagaatt ttctttttca taaggctccc tcagtagtta
    15061 gtattaagca ttctgattat accatagtgt tatttcctat caagctctcc tagatgattt
    15121 aatgattttc cccaaacttc ttctgcaatg cttttgacaa aagaaatttt ttccattgtt
    15181 cttcaaacaa aacattttct tcttctgttg aagcaaatcc acattgagga cttaagcaca
    15241 aacgatccaa aggcagatat cgtgtcgctt cgtagatccg gtcaatcact tgctggtgct
    15301 cttccatttc gccatttttc gttacagtca aaatctaaga caactaattt atcttcagag
    15361 actttctcta aaagaacaaa actcccagca cgttcactat cgtattctaa ataataggca
    15421 cggacatttt cttgagtaaa ataatgggtc tgctacgtcg tcatcccccc tgatgccgcc
    15481 aaaatcgaat aataatttcc gcgtcaaaca tgtatattta gtgttgaatc atttgagaat
    15541 atgaaaataa aaatcttttt gatcaatcag ttaatcaaat tgaaataacg aaaaatctga
    15601 gacagaatga cgttcattct gacccagatt tgattttgca caactcaaca gtccttattg
    15661 gcaaatcgcc aaaataatgt agactaacta aaaagactaa gaaacaataa caaaagttaa
    15721 cacttcttag tctttcttta gcacgtctat ttattaaaga ttttagggcc ttttctcatg
    15781 tttttacgat cattcttagg tgtttccatt tgtttggatc ggcctccacc ttgtttcttt
    15841 ttgatcaatt ctttcatttt ttctttttgg tccattttta ttctccttta acgaatgaag
    15901 cgactaattc gatatgatgg gtttgcggga aaagatctac aggctgaact ttcttcacgg
    15961 cataacctgc ttctgcaaat aacttagcat ctcttgcaaa agttgccgga ttacatgaga
    16021 tatagacgat tcgttctggt gacatttcga ttgctgattc aataaaatga tgatctaatc
    16081 cttttcgtgg agggtcaact acgatcacag atggtttgat ccctttttct tgccattttt
    16141 tcataacttt ttctgctttt ccgacttcat aatgaacatt ttcgatttta ttatttaaag
    16201 cattgaactg tgcatcttca attgcttctg gaataacttc catcccatac accttatcca
    16261 ctctgtctgc taaagacaag ccaatcgtac ctattcctga ataagcgtcg atcacaatgt
    16321 cttttttatc taactcggca aactcgatgg ctgtttggta cagatactct gcttgttgag
    16381 tatttacttg ataaaatgac tttgctgaga ttcgataggt ttttcctaat agctgatctt
    16441 cgatatagtc tctgccatat aaaacttttt ctttgtctcc taaaatcaca tttgtttttt
    16501 cttcattgat attttggatg accgaaacca cttctggcaa ttcttcatga atagcttcag
    16561 caatttcctt ggatttaaag aatttttctt tacgagtaac taaaacgacc atcatttcat
    16621 gggaataatg accacgacgg ataatgatgt gacgaagctg tccttcattt ttttcttcat
    16681 tatatcctcg tacttggaac cgttgcaaga tatctctgac tactttgatt gcttgatcga
    16741 tgacaggatc ttggatataa aaatcttcga tagggactag atcatggcta ttctttttgt
    16801 aaaaaccggt ggctaactgt ccatcgatac ggcgaacagg gatctgtgct ttattacggt
    16861 agccgaatgg ttctgccatt ccgaccgttg gaagtacagg aacttctggc atcttagcaa
    16921 tcttcgccat tacatgctct acttgttttt gtttgaagac aagctgttgt tcatacttca
    16981 aatgggctaa aggtgcgata cctatgcgaa gtaatgcatt gttttctaca ggctgacgat
    17041 caggtgattg tgtaataaat gtttcgactt ttccatatcc aaacttattg cctgctttta
    17101 ctactagtat ttctacttct tctccaggga gtgcattttc gataaataat ggataaccat
    17161 cgatttttgc tacccccatt ccttcataac tcaagtcgac gatttcgact gtatatcgtt
    17221 cgtttttctt tactatttgc tgttctgtca tattttgctc ctttaagcct atttttcaat
    17281 cctactgaac tctactataa atcagctaat tacacaacta aaaccggcac tgaccttact
    17341 acgttcagca ccggcttttg attaattctt ttgattaggt gtttcgtctg ctatttttcc
    17401 gtcaccgtcg atatcttcat ccgttaaacg ttcgacttct tttacgaatt ctttgctgac
    17461 aacctctaat tcttcttcat ctgtacctgt gattgcttca tcaggaatct gatcggtatt
    17521 ggcaaagaac tcaatgtgtt gatgaagatt ttggaaatgc atcggtgctt ccccgccgta
    17581 ttcaccatct aagttgatca ttactggtcg attgatatca tcttctgttt caacgaacaa
    17641 actgcttgtt ttggtataga ttattcttgg atcatcggca tgtcgaccgc cattcagcat
    17701 gagtgctgca atatgcaaga tctcaaagat atttgctgtc ttcacaatga ttaaagaaaa
    17761 cttcccatca tccaatttgg catctggcgc gatctgttcg aatcctccaa cagagttcgt
    17821 cagccctagg aaaaacatcg aagcatttcc gatatattcc ccttcatcat acttcaagcg
    17881 cattttgatt ggctttactc gagggagcat ctctgctcct ttcgcaagat aagcaagata
    17941 accaaaaata ctctttagtt ctgatggaac ttcataagtc aattctgtca aatagccacc
    18001 tgcagcgata ttgatgaagt aactgttatc agaaaggccg atgtccattt ttacggtttg
    18061 gtgttttttt atcacttctg ctgctgcttt aatattatct ctaggaattt ttaatgctcg
    18121 agcatagtcg ttcgttgtac cagctgggat gatggccatt ttaggacggt gttcaagcgg
    18181 agcgattcca ttaaccactt cgttgattgt gccatcgcca ccagctgcca ctactagatc
    18241 aaaacctagt tctgcgactc tacatgcttc attcttggct gaatctggtt ctggtgtagt
    18301 tgcataggcg ctggcttcaa atcctgcttc ttctaatgcc tgtaggatat ccgccaaatt
    18361 ttttttcaat aattcttttc ccgaggtggg gttataaatt acgcgtgctt ttttcatttt
    18421 cagcctctat cgtttcgcta attcatcttt aagtagctta ttcacgacac caggatttgc
    18481 ttgtccttta gttgctttca tgatttgacc gactaggaag ccaaccgcac gatcttttcc
    18541 atttttgaaa tcatcgacag attgttggtt gttatccaaa atttcattaa tgattggcag
    18601 tagtttgttc ggatcagata attgcaccca accatttttt tcaactactt cttgggcttc
    18661 tccgccattt gtgatcaatt cacggaagac ttttttggcg atttttgagc tgatcgttcc
    18721 atcggcgatc aaacgaatca ttcctgctaa gttctcaggt gtcaattttg tctcagctaa
    18781 ttccagtttc tcactgttca agtaagcaga aacttcaccc atcaaccagt tagatgcttg
    18841 cttggcatct gcaccatttt ccaaaacagc ttcaaaaaaa tcagacattt cttttgtaag
    18901 tgtcaatacc attgcgtcat actctggaag tccaaactca cggatatagc gttcgcgacg
    18961 agaagctggc atctcaggca aactagcttt tactttttga atccattcgt catcgatcac
    19021 gaatttcggg atatcaggct ctgggaagta acgataatca ctagaccctt ctttgacacg
    19081 catcaaaact gttttattcg ttgtttcgtc aaaacggcgt gtttcttgtt ggatttctcc
    19141 tcctgaaaga agaacttttg cttgacgttt ttcttcaaaa gctaaacctt ttttcacgaa
    19201 agataaagag ttcaagtttt tcaattctgc tttcgtaccg aactcttctt gtccataagg
    19261 gcgaagagaa atattggcat cacagcgcat agagccttct tccattttca catcgctgac
    19321 ttctgtaaat tggataattg atcgcaatgc ttctagataa gcgtatgctt cttctggtga
    19381 acgcatatca gcttcagaaa cgatttcgat caaaggcgtg ccttgtcggt tcaaatcaac
    19441 gtaagaataa ccgccaatac catgcatgtt ttttccagca tcttcttcta aatggacacg
    19501 ttcgatccgg atttttttct ttttaccttc tacttcgatt tcgatccatc cgtcatgacc
    19561 gattggttga tcaaattggg aaatttgata tgcttttgga ttatctgggt aaaagtaatt
    19621 tttccggtca aaatgagtat ctttagagat ttcacagttt aatgccaaag ctgctttcat
    19681 cccgaattcc agcgcagctt tattcattac tggcagcacg cctggataac cccagtcgat
    19741 cacgtttgta ttgctgtttg gttctgcacc aaaatgagct ggcgctggag agaaaatttt
    19801 tgagttggtt tttaactcga cgtggacttc tagtccaatg actgtttcaa aattcattcg
    19861 tctttccctc ctaaaatagc tggttgttgt ttatggaatt ctgttgcttg ttcaaacgca
    19921 tatgccgctt gatacatcgt tttttcatca aaataattac cgatgatctg caatccaact
    19981 ggtaatcctt ctgataaacc tgccggtaca gacatacctg gaagtccagc caagttgaca
    20041 gggatcgtta agatgtcact catgtacatt gtgattggat cgttaatgtt ctcaccgatt
    20101 ccgaatgcaa ctgttggtga agatggcccg atgatcaagt cataatctgc aaagactttt
    20161 tcaaaatctc gtttgatcaa tgtacggact tgtcctgctt ttttgaagta agcgtcataa
    20221 taacccgcgc ttaaggagaa tgtacctaac atgatacggc gttttacttc ttcaccgaat
    20281 ccttctgaac gtgagttgac atatacatca tctaatgatt tcacattttc agagcgataa
    20341 ccgtagcgga taccatcgaa tcgttgcaaa ttggaacttg cttctgatga ggcaatgata
    20401 taataaacag ccacaccgta ttttgaatga ggcaagctga cttcttccac aacagcacct
    20461 aatgaacgga atgtttctgc tgctttcaat acagcttctt ttacgccagg ggccacacct
    20521 tcgcctaagt attctttagg taaagcaatc ttcattcctt tgatgtcgcc tgtcagtccc
    20581 tctgcaaaat caggaactga aacgcctgaa gaagtaccgt ctttttcgtc ataaccgctg
    20641 atagctgtca atgctaatgc attatctttc accgtacggg tcattggtcc gatttggtca
    20701 agagatgaag caaaggcaat caaaccaaaa cgtgagacac ggccataagt aggtttcatc
    20761 cctacgatgc cgttaaaagc tgctggttgg cggatacttc ccccagtatc actacctaaa
    20821 gaaactggaa tttgtccagc tgcaactgct gctgcagaac caccagaaga gccaccaggt
    20881 acttttgttg ggtcccaagc attttttgtt ttcttgaaat aagaagtttc tgtacttcca
    20941 cccatagcaa attcatccat gtttagctta ccaacaggga tcatatctgc ttgatagatt
    21001 ttatccatga ccgttgcatc ataaattggt tcaaaattgt aaaggatctt agatgcagcg
    21061 gttgtcaaga tatcttttgt tacgatatta tccttgatac caattggaat accagcaagg
    21121 acgttgcttt catcaatccc tttttcatct aaagcttttg cctgttccaa tgctttttct
    21181 tcgttcaatg taatgaatgc ctcgacctca ggctctgttt ctttgattcg ttcaaatgtt
    21241 gtttttgtca aatcttgtac agtgatttct ttcgatacaa gcatatgatg cagttcttct
    21301 agagaacgat tgtgtaattc tgtcattatg cgccagcctc cccattatcg atgattgcgg
    21361 gtactttgat aaagccgtct tctgtttccg gcacattttt caataattca tcgcggttcc
    21421 atccagcttg cgcccgatct tgtcgcatca cgtttactgt ttcaaccaca ttcgacgtaa
    21481 atggaacacc ttccgtatct acttcttcca gcatttcaac catatcgatg attttaccta
    21541 attggtcggt aaaacttgca agttcttcat ctgcgaacgc aagttttgct aatttggcaa
    21601 cgtgtttcac ttgttcttca ctaatcgcca tactacccct tctttctaaa cgagttaaaa
    21661 actttgctct ctattttaac acaagagtgc cgtgtctgaa attgtttatt gaaatttgtc
    21721 tgaaaaaact catttttcat tcttctactg agcgactttt agccaatgca tctgccattt
    21781 gatcttctgt ccaaacttcg attcctaatt cttgtgcttt ggtcagcttg ctgccagcat
    21841 cttctcctgc taccacgata tccgtttttt tcgatacgct accagtcact ttcccgccaa
    21901 gattttcgat cgtctctttt gcttcttcac gagtaaatcg tgttagttta ccagtaagga
    21961 ctactgtttt ttctttaaaa ggagactcga cttcttgcaa ttgggcattt cgaagccctt
    22021 tgtattcgaa attgacgcct gcttgtttta attcattcat caattcatgg acttcttcgt
    22081 tactgaaata agtgactaca ctgtcggcaa tgatatcacc gatcgtatca agcgcaataa
    22141 tcgactcata gtcactttta ctcaatgttt ctagatcacc gaaatgttct gctaaaattt
    22201 ttgctgcttt cgctccgaca tgtcggattc ctaacccgaa aatcaaccgc tcgaccgaat
    22261 tatctttgct gttgtcgatt gctgtcaaaa tattatttgc tgatttttct tttattttgt
    22321 ccaacgtcaa taactcttct tctgtcaatt tgtaaagatc agcaacatct gctactagtt
    22381 ttttatcata catctgttct agtacgcgcg gccccaaccc atcgatattc atcgcatttc
    22441 ttgaaacaaa gtggttcaaa ccttctttca tttgagcagg gcatttagga ttgatgcacc
    22501 gtaaggctac ttcttcatcc aaatggacaa gttcacttcc acaaactgga caatgtgtag
    22561 gcaattggta ttcttcgctg tctttaggtc gtttatctaa cacgacttgc gaaacttctg
    22621 ggatgatgtc tcccgcttta taaatcagaa ctgtatcttt caagcggata tccttcaact
    22681 taatataatc accgttatgc aggctggcac ggcttactgt cgttcctgct actcggactg
    22741 gtgtcatgat agctgttggc gttactaccc ctgttcgacc gactgtccat tcgatgtttt
    22801 cgattagcgt ttcaacttct tctggcggaa acttgtaagc tgctgcccat ctcggtgctt
    22861 tgatagtaaa accaagttga tcttgtagcg agaattcatt cactttgatg acgattccat
    22921 cgatttcata gggcaaatcc acacgtttgt catgatattc ttcaatgtat gaccacactt
    22981 catcaatcga atgacataga cgtttttccc gattcgtgtg gaatccaatt ttttctagct
    23041 cttctagcgc atcatactgg gtttttgctt gcataggacc gaaatcagct actgtgtata
    23101 aaaaagtgtc cagatttctt ttcgctgtga ttttagaatc taactgacgc aaagaaccag
    23161 ctgcggcgtt ccgaggattc gcaaagatat cttttccctc tgcttctctg tcttggttca
    23221 attggacaaa tgaccgtttt ggcatgaaac attcgcctct tacttcgatg ttcattggtt
    23281 cttttaattt gattgggacc gaccggacag tttttaggtt ttcagtgatg ttttctccta
    23341 cagttccatc cccgcgagtc gcacctctca cgaaatttcc atcttcataa cgcaaagaaa
    23401 cggaaagtcc atctattttt agttcacagc aatagtcaac tacacgtccc actgcttttt
    23461 gtacacgttg atcaaaagct atcagctctt ctttgctgaa aacgtcgttc aaactgtaaa
    23521 gcggaatatc atgagtgact ttttcaaaac cttctaatac ttttccgcct actcgttgag
    23581 tgggagaatc agacgtgatc aaatcaggat attgttcctc gattgctact aattctgcgt
    23641 attctttatc ataaacatag tcttccactg ttggtttatc ttctacgtag tattcgcgag
    23701 accattggtt cagtcttgta cgaagttctt ctgctcgttt agcagcttcg tcaatcgtca
    23761 tttcatgttc catcatttac cctccactac taagcttttt caattggcgc aaaggcagcc
    23821 aaaagacgtt ttactccttg acttgggaaa gccacatcta gttctagatc cttcgacgtc
    23881 ccgcttactc ggacgactgt tcctagaccc cattttttgt gtttgacttt atctccaggt
    23941 ttccagctgt tattttcccc tccagtagca cttttagagg gaacaaccgc tgtctctggc
    24001 tgtttatagc tatatgctgt ttttttagcg aatacaggcg tttttttagg cgtaggacgc
    24061 atgccttcga tttccagtaa ctcctgatcg atttcttcta caaaacgaga aggtcggtta
    24121 tattgcgtcc gtccatataa tgttctggag aaagcatttg ttaaatacaa cgcttcttct
    24181 gctcgcgtga tccccacata tgcgagacgg cgttcttcct ccagttcgct ttcttccatc
    24241 aatgctcgag ataaaggaaa aaccccctct tctagaccaa tcaggaatac aactggaaat
    24301 tctaatcctt tggctgcatg caaagtcatc aatgtcactt gggaagcatc ttcttctaaa
    24361 ttgtcaatgt cggaaacaag tgccagatca tttaagaaga ccgttagttt ttcttctggt
    24421 gcatcagcgt cttcttcatt ttgctgttcg aattgtttgt cgaattcttg tgtgaccgtt
    24481 aaaaattcct ccaagttttc gatgcgtgct tgtgcttcta atgtattttg gatttttaag
    24541 tcttctagat atccgctacg atccaaaacc tctttcgtca attctgtcac tgtcaagtat
    24601 gggatcatct gagtgacttc ttggatcatc tctccaaatg cacctaattg ctgtcctgct
    24661 tttccaccga tatttgccag atccacattt tgcgctgctt caagcagtgg ccattcatga
    24721 agagaagcaa aactgcgtag tttttcgata gatcctggtc cgatgcctcg tttgggcgaa
    24781 ttaacgatac gctcaaaact gattgaatct tgaggattta ccagcacatt caaatacgct
    24841 aaaatatctt tgatttcttt acgatcgtag aacttgtgcc ctccaaccat tttataagga
    24901 atatttgctt tcaacagagt ttcttccatt acacgagatt gtgcgttcgt ccggtacaag
    24961 atggcaaagt cgccgtaatt ccgatgattg cttcgaatct cttcttgcat ccggtctacg
    25021 ataaaacggg tttcgtctcg ttcattatct gcacggtagt aagtgatctt gtttccttct
    25081 ttgttttctg tccacaagtt ttttggtttt cgattgctat tgttttcaat gacttggttt
    25141 gctgcgctaa ggatgttttt cgtggagcga tagttttgtt ctagcaaaat tactgcagca
    25201 tctggataat ctttttcaaa atccaagatg ttctgcatat ctgcaccgcg ccagccgtaa
    25261 atactttgat ctgcatctcc cacgacgcac aggttcctaa atctacctgc caataaattg
    25321 actagcgtat actgtgcgtg atttgtatct tggtactcat ctacatgaat ataatggaat
    25381 ttgttttgat aatacgtgag tgaatcagga tgttcttcaa ataatcgaat cgtattcatg
    25441 atcaggtcgt caaagtccat acattgatta tattgaagct ctttttggta agcagcataa
    25501 cattttgccg caatctcttc gtaataactg ccttgcattt ttgcaaaatc ctgaggggtc
    25561 tgcaggctgt tttttgcttg agagattgtt cctaatatac ttcgaggatc atattttttc
    25621 ggatcaatgt tcagttcttt tagtatccgt ttcatcaagg tcagctgttc agaagaatcg
    25681 atgattgtaa agttccggtt atacccgata aaatcaacat ctcttcttaa aatacgcaca
    25741 cacatcgagt gaaaagtcga tacccagaca tcttcgcctc cagatgcgag aatcgcattg
    25801 acacgttctt tcatttcttt tgcagcctta ttggtaaaag taatcgctag gatgttccaa
    25861 ggattgactt ctttttcctc aatcaaatag gcaatgcggt gtgtcagcac tctcgtcttt
    25921 ccacttcctg cacctgccat tagcagtaat ggtccgtcag tgtgaagaac agcttctttc
    25981 tgacgggggt tcatcccgtt taataattca gctttggatg acattaacaa catcctttct
    26041 tttatcaatc ttgttaatta tagcattttc ttggctttca ttaaactagc tagttcaaaa
    26101 tcatttgttt ctttttatgg atttttcctt gtcaattcgt tgatttcgcg ctaaattaaa
    26161 agaaagcgag gcgtttgaat ggaaaaaaaa ggaaaaatca agaaattaga taagactcag
    26221 atatatttta ttctaaaagg aatatttgtt ggactgctga caggaatcgt cgttagcctg
    26281 tttcgattat ctatcgaaaa gctaagcgat ttagttcgaa gtatctatga aatgagtcgg
    26341 gaacagccga tttacttaat tggcctagct atttgctgca tccttgcagc atttttcgtg
    26401 ggttatctgg tcaaaaatga accggatatc aagggaagcg ggattccaca agtagaggga
    26461 cagcttcgcg gggaattatc aatgaactgg ttctctgttt tatggaaaaa gttcattggc
    26521 ggtgtacttt cagttggtgc gggccttttt ctaggtagag aaggaccttc tatacagctt
    26581 ggcgcatcca ttggacaagg agctggacaa ttgtttcgga gtccatcttc agaagaaaag
    26641 attttaattt ctagcggtgc aagtagcgga cttgcagcag cattcaatgc tcctatcgca
    26701 ggattactct ttgttttaga agaaatccat cactcctttt ctccacttgt ttggctgaca
    26761 tcatttgctt cagcaatcac tgctaacttc gtctctcttt actttttcgg cttgagacct
    26821 gttttatatc taggtgacct tccttctttg ccgttgaaat attatggttc cttagtgatc
    26881 ttaggagtac ttctaggcat cttaggtttt atttatcaga atgtcttgct ggctttgcca
    26941 aaattttaca accgattgcc tttaccagct tattttcacg ggttcgttcc tttcttgctg
    27001 attttgccaa ttggttattt atggcctagt actctaggcg gaggcaatca aatcgtttta
    27061 gcttttggac atgcttcctt gccaatcatt atgattatcg gtttgtttgt tcttcgattc
    27121 gttttttcca tgatttctta cggtgggggt cttccagggg ggattttcct tccgatattg
    27181 acattggggg ctttaatcgg tagcttttat ggaaacatta tggttgattt cgggatggat
    27241 ccaatctaca tcaaggattt tgtcgttatt gccatggctg gttatttcac agcgattgga
    27301 aaagcaccgc tgacagcaat tattttagtg acagaaatgg ttggctctct taatcatctg
    27361 atgcctttag gattggctgc tcttgttgct tatatcgtca atgaccttct cggcggtaat
    27421 ccaatttacg aatcattatt ggaacgtcta cttggaaata ctcagaccgc ctcactaaaa
    27481 ggtgcaagga caacttttga ttttccagta acggcagaga gttctttaga cggattaatg
    27541 gtacgagact tcaattggcc taaaaatatg ctgctaatct ctatacgcag aggaaatcag
    27601 gaaatcttga ctcacggtga tacgatcatg aatgtaggag atattttggt tatcttgact
    27661 gatgaagcaa acttgccaag aatcaagcag gaaatcgagg ctaaatcttc tatcacaaat
    27721 ttgaagcaat cattttaacg aacatggaaa aactatttta caacaactat tcatctacac
    27781 tacttgattc tatatgattc tataaaaaag aagaggctgg gaaaacccag cctcttcttt
    27841 tttatttcta tgcttctgct actgcaggag cttttctcaa taaaccataa atcacaccag
    27901 atacgactgc tccgatagca ataaacacca aatacatgac cgggtgactc agtaagaata
    27961 caacgaaaat cccgccgtga ggagccagta atttgattcc gaaagctccg actaatccgc
    28021 cagttaaagc agaaccaata ataaaacttg gaatggcacg aatcgggtca gctgctgcaa
    28081 atggaatcga tccttccgtg acaaacgata gtcccatcac gatgttcgtc aaaccagcat
    28141 cttgatctgt tttgctgaat ttattcttaa acaaacgtgt agcaacgaaa attgccaatg
    28201 gaggtaccat tcctccagcc ataacagaag ccatcacgac acttccgcca gttgcaacag
    28261 tcgtagctaa agttgctgta ccaaacacat aagcggcttt gttgattgga ccgcctaaat
    28321 ctgccgccat cattccagct aataatgcac caagtaaagc agcattcgaa ccactcatac
    28381 ttgtcaagaa accgttcaat gcatcattga ttgctttcat agggacattg accagcaaca
    28441 tcaagaaacc agtaatcagt aagccaaaca ctggataaaa gaggatcgtt ttaattccat
    28501 ccaatgattt tggtaagttc ttgaataatt tacgtaaaaa tacgatgaca taaccagcta
    28561 agaatccacc aatcagtgca cctaagaatc ctgcaccgcc tgtattagct aatgcaccag
    28621 cagcaaatcc aacgatcaaa ccagggcggt caccgatact tgaagcaata aatcctgcta
    28681 ataccggcag catgaaacca aatgcagctt gtccgatttg gttgaaccag ctagcagctt
    28741 gattgtaatt ccctagattt gataattgat catgtggcac gccaataaat tggtcgatca
    28801 tgaaagaaag cgcaatagcg attcctccac caataacgaa aggtaacatg tgtgatacgc
    28861 cgttcatcaa atctttgtaa attctttgtc cgatagtacc atccgcattt ccttcttctg
    28921 aactgctttc ttttccatca ccatggaata ctggtgcagt accactaagg gctagattga
    28981 tcaactcttc tggtttacgg ataccatcac tgacaggacg attgatcagt tcttttccgt
    29041 caaagcgatt catctctact tttttgtctg ctgcaacgat tacaccttct gcacgggcga
    29101 tgtcttcagc agtcaatcgg tttttgattc cttctgaacc gttcgtttcg actttgatct
    29161 ccacacccat ttctttcgct tttttcttca aagcatcttc tgccatgtaa gtgtgagcga
    29221 tccctgttgg acaagctgta acggcaacaa cgaattttct ttctggatga gcagaagctt
    29281 ctgcagcttg tgtttcttgt tctgcttttt cttctgcttc tttttgctct tcagctgttt
    29341 ggaacaagtc ttggacttct tctggtgtat ttgcttcttt taattttcct acgaaatctg
    29401 catcaatcag caatcgagat agtgctgcta atgcttgcaa atgtgtgtcg tttgcgcctt
    29461 ctggagctgc gatcatgaaa aacagataag ttggctgtcc gtctaaggct tcataatcta
    29521 ctcctttttg gctttttgcg aataaaactg ttgcttcttt aactgcactg tttttcgcgt
    29581 gaggcatggc gattccatca ccaagacctg tagaagtttg tgcttcgcgg gctagaattc
    29641 cttctttata tgtttcgata tcggaaatcc ggccggcatc aaacattttt tggaccattt
    29701 catcgattgc gcctttttta tcagtcgctt gcaaatccat gatcatcgct tctttgacca
    29761 ttaaatcctt gatattcatg attatcctcc ttgaaactaa tcaatttttg tgatttcaac
    29821 ttctggcagc aactcatcaa tcaattcgcg agctgccaag tcatcagaaa aagctgttgc
    29881 gcttccgcaa gcaactcccc atttaaaggc ttcgattgga tctttcgtac ggctgtaagc
    29941 cccaataaag ccagcaatca ttgaatcccc tgcacctact gaatttttca atgggcgaac
    30001 taatacattc gttttataag ttccttgttc cgtgaagagc aaagcaccgt ctccagccat
    30061 tgagatcagc acattctgtg ccccttcagc tagtaatttt ttcccatacg gaatgatttc
    30121 ttctacagat tggaaggttg tgttgtaaag ctcagctaat tcgtgattgt ttggtttgat
    30181 caacaacggt ttcttaacaa gtgcattttt taggtcatca cctgttgtat caatcacgaa
    30241 atctgcacct ttttctcgaa tgatatcaat cagttcttga taaaatcctt ttcgcaggct
    30301 agctggcgcg cttcctgaca atacgacgat atctccttgt cctactgttc ctaatgcttg
    30361 cttcaactca tcgatttctt catctgaaat agatgggcct aagccattga tctcagtttc
    30421 agtgtctgat tttagtttga tattgattct tgtatcttct tttacggttg tgaacaaaga
    30481 ctggatttgt tctttttcaa gccacttcga aataaattcg ccagtgaacc ctcctaaaaa
    30541 ccctagtgct gtagattgag aatcgatccg tttcaaaata cgggaaacat tgatcccttt
    30601 tcctccaggt aacttgaagt cttccttcat tcggttcaaa tcgcctagtt ttaacccatc
    30661 tacgcgtacg atataatcaa ttgatggatt aagtgttact gtgtaaatca ttgtattgcc
    30721 tccttaattg ttgtcttttc acggaattca ttaacgaatt ctaatggaca acgctcggtt
    30781 atgatcgtgg ctgcttccaa aggtgcaaca gaggtgaagg acaactggtt gaatttggta
    30841 tgatcaatca atacaaatgt ctcttcggaa tttttcatgg ctaaacgttt aacagctgcc
    30901 tcttctggat ccggagtcgt gaatccttgt tcaagatggg caccgttcat tcccataaat
    30961 gctttattaa aatgaaaatt ttttagttgt tctatcgcat tagatcctaa aacagcatta
    31021 gttgccagct ttatcgttcc acctaaaata atggtagcaa gctccaaatc aactaaattt
    31081 gccgcatgtt gaacggaatt tgtcactact gtgatctgtt ttccttgcag aaaaggaatc
    31141 atttctaacg tagtagagcc agcgtctaaa taaatgacat cttcgtcatt aatggtttca
    31201 gctgccgatt tggcgatttg ctgtttttcg tgaacgtttt tgagtgattt ttcactcata
    31261 ttctgctcaa aattcaataa ttgctctttc ttagctccgc catgaactct ttctagaaac
    31321 ccactattct ccagctcttg taaatcacgt cttatcgttg attcagaagc attcaaaagg
    31381 tttacaagat cttgtgattt cacgattttc tgctgttcaa gcaagtctag gattttttgt
    31441 ctgcgttcct ctgtaagcat tttcacgatc acctcaatac aaataatagc atattttttt
    31501 tctactagca atataaatca gtcaaaaacg ttcataaaag ttataaatca gtcaaaaaaa
    31561 aaaataaaaa accagtcaga aagactggtt ttttattttt ttgtctatca tcaagccgtt
    31621 ttatcgtttt ttattttcgc ttcttgtttt tttcatataa acagaagcag gttttctttc
    31681 cttatgaaga agataataat aaagtcccat cccgccaaac atgaccaaaa aaccgatgac
    31741 tgatcgaata ggaaaattag gaacaaaaaa gagacagacg gataataatg atgccggaac
    31801 cattattcga taatagagtt gtttatccat tttcttcacc tcatattttt tgtaaagtaa
    31861 tcaattgttc taattctcgg taatctaaaa attgcacacg cagatgctgc tcacctttct
    31921 tgacatcgaa ttggatactt cgccgctttt tctttattcg tttgaaggta acatcagaga
    31981 gtctatgttt gatttccttt aacggtaatt ctgacaggga ttctgaagga acatagattc
    32041 ttaaggataa aagatactct tgatattttt catctgttac ctctacttct agatattccc
    32101 taatataata acaataagct tcgattccat tatccaaagc aacagtcgga tcgataactt
    32161 tatagcacat catgcgtgat cgattctcgt caacccaagg aaaatacgcc tgagcattta
    32221 gtgttccgcg aacacgcctt tctttataat ctccttgttg gatatcataa ctttttgtta
    32281 caaaaaatga agcattcttt ttaggaacag gttgcatttg tgcattctga tactggacag
    32341 attggatcgt atggtcagtg taaatgtatt caacgaatgg cggtttcaat aaaccgacac
    32401 cattgtccca agcaagatga tcaaacccaa gctggtccct aaaataggat tgaaacattt
    32461 gattgtttgg cttttgccag ttaaaggggt ctcgataaag ctggatacat atgacttcgt
    32521 tttctaattc cttcactttt tctacttgtt ggatgtcgag aaaaatcggt ttagggatga
    32581 tttgatgata atagcgacta taatacattt cccaacacga agtgaaacat aaaccttggt
    32641 aaaaaagatc gtatcctgga aattggttgc aatcgactac tacttccccg ttttgttgtt
    32701 tcattttagg taaatgttcg atttcatcct ttttctcaaa caatagccgt tgagagatct
    32761 gttttgtatt gtgatagata aactcgctat aagctcgcat ataggcgaac accccatgag
    32821 caatcatttt tttctgaatg aagtctcgaa tcaaaaattg cttttctttg aaaacagaga
    32881 tagacaatac attttttatc aataattgat tatcttccaa gcgaaaacta cattcgttct
    32941 cgtcatttcc tacaactaac caactttcgt ctcttaccga tgctagcatt attttttctt
    33001 gaagctttcg aagatcatac ggatccgctt gttgtgtgaa agagcggata aatgttggct
    33061 ggatcaacag acgtgtcaaa atagcccaat cgcttatttc ctgttttttt tcttcttcat
    33121 ttaagtctgt gagctggata gtcatcaata atttatcttc gccaatcatt ttctcacctc
    33181 tttcaaatct ttttataatt taattataac caatgataaa gaaaaactaa aactttatgt
    33241 cttagaaacc aatttggacg attacatgat agactaagta aaaagaaaca aagaggtgtt
    33301 tacaatgggg ttgaaatttg aacgtacaga taatttagat aaacttttcg aatcatttgc
    33361 tgtcgatccg gaaaaaacag ttgcaccaaa agaagagatc gatcgatttc taaaaccaca
    33421 gccacaaaat gaaaagaaaa aagacaagaa acaaaagtaa gttaagctca aaaaaagact
    33481 taccagccaa acttttatga aagagtttga ctggtaagtc ttttttattc tttttatgat
    33541 tcaattgctt gttcgattgc tgcccacgct tcttcttttc cctgttttgt aacggaagaa
    33601 aagagaataa acgtgtcatt gcgatcaaaa tccaacgctt ttttgatttc gctctcatgc
    33661 ttgttccatt taccacgagg gatcttatct gccttagtgg caacaacaat tacagggata
    33721 tcataatact tcaaaaattg atacatctgg atatcttctt gagaaggctt atgacgcaaa
    33781 tctactaaag aaacgaccgc acgtagctgg tctctagtcg ttaaatatgt ctcgatcatc
    33841 tttccccatt ttgctcgctc agttttggat acttttgcat acccatatcc cggaacatcg
    33901 acaaaatgta atgcgttctc gatcaaataa aaattcaatg tctgggtctt tcctggctta
    33961 ccggaagtac gggctaaatt ctttcgatca atcaatgtgt tgataaaaga agatttccct
    34021 acatttgatc gtcctgccag agctatttct ggcaattgtg tatctggata ttgttttggt
    34081 gccactgcac ttatgataat ttcagcttga tggactttca tggtctctct ccttaacaag
    34141 gtgatgaata aagcaagcgg ctgtcgcaaa agccaaaatg acttttacgg cagcctcttt
    34201 tcatcaaccc gcttttttct ctgaatcttt atagattact gttggctcac cagacaattc
    34261 agctgcttct tttgtgataa tcactttttc gatgttttca tttgaaggga tatcaaacat
    34321 cacatccatc atgatttctt caatgatgga acgaagtcct cgagcaccgg tattgcgttc
    34381 gattgctttt ttcgcaatgg ctctcaacgc ttcaggttcg aattcaagtt cggtattatc
    34441 tagagaaaga agtttttgat attgtttgac tagcgcattt ttcggctcag tcaagatccg
    34501 taccagatca tctgttgtca atttctctaa agctgccata acaggtaatc gtccgataaa
    34561 ctcagggatc aatccgaatt ttagtaaatc ttcaggaatg atatgctgca tgacactttc
    34621 gtcttcagaa agtttttggt tttgtgtacc aaatccaatc gtcttttcgc ccatacgatt
    34681 cttcacaatc gtttcgatgc catcaaatgc accacctacg atgaacaata tgttcgtcgt
    34741 atcaatctga ataaattctt gatgtggatg tttacgtccg ccctgaggtg gcacacttgc
    34801 aacagttcct tctagaattt tcagcaaggc ttgttggaca ccttcgccgg aaacgtcacg
    34861 agtaatagat acattttcgc ttttacgcgc aattttatcg atctcatcaa tatagatgat
    34921 ccctttttct gcaagttcca cattgtaatc agcagattga agcaatttaa gcaaaatgtt
    34981 ttctacatct tcccccacat aaccagcttc tgtcaaactt gtcgcatctg cgattgcaaa
    35041 aggtacattc aatgtttttg ctaatgtttg tgctaaaaat gttttaccag accctgtagg
    35101 tccgatcaag cagatattgc ttttttgcag ttcaacatca tctgtgtttt cttgtgcttg
    35161 ctgattgaca cgtttatagt gattgtatac ggcaacagct aacgagcgtt ttgcgcgatc
    35221 ttgtccaatc acgtagttat tcaatacttc aagaatttct agtggtttag ggacttcagt
    35281 gaattcgcgt acagcttctt cataaaattc ttcatcaatg atttctttac ataggtcgat
    35341 acattcatta cagatgtaga cccctggacc agctacgatc tttttcactt cttcttgggt
    35401 tttcccgcaa aaagaacagc gtacggtctc attgctactt ggattgtcat acatggtctt
    35461 caccccttaa cttgcaaaaa gtatgcaaga aactatcaaa gactttacag tcttttacta
    35521 tcataacata gtttagtaaa aagaaaaagt gtttaacaaa ggatcaactg acctatacct
    35581 ttgcattttt tactcttaac aaaaaataag gaactgtgac aaaatcgtgt cacagtccct
    35641 tatttcgaat aaacaatttt ctagaagtag cttcttcaga aatgatttat tacttgattt
    35701 ctattctttc gcttctgtcg ctgtacctgt gatcaattcg attgcttttt tcattgtcac
    35761 atcatgttcc agcatatctt ctgtcaacac gcgtttgatt tgttcgattg gcatgttgta
    35821 tgtttctgat aattcttgga tttctgcatt gatttcttct tctgttgctt gaagattttc
    35881 agcagctgca attgcttcga tcacaagatt tgttcttgtg cgcatttctg cttcaccttc
    35941 gaattgttta tgcaagtctt cttctgtaga accagttaat tgatagtaca tttcaggaga
    36001 gataccttga cgttgcatgt tgttcaagaa ttcgtccatt gaacgatgta cttcatcatg
    36061 aaccatcacg tgtggcaatt caacgatttc tgcgttttca acagccatac ggatcgctgc
    36121 ttcatctttt gcatcgtccg ctgctttttc ttttgtttct actaattctt tgcgatattt
    36181 ttctttcaat tcgtctaatg ttgatacttc gtcatcaaca tcttttgcga attcgtcatc
    36241 taattcaggc acttcttttg cttttacttc atggattgtc actttgaaga ctgcttcttt
    36301 tccagcaaga tcttctgctt gataatcttc tgggaaagtt acatttacat ctagactttc
    36361 acctgattta tgaccaacta attgatcttc aaaacctgga atgaatgagc ctgaacctaa
    36421 ttcaagtgag taattttcgc cttttccgcc atcaaacgct tcgccatcta caaagccttc
    36481 gaagtcgatt actactgtat cgccattttc agctgcagca tcttctttga taactaattc
    36541 agcttgtgct tcttgttcac gtttgatacg tgcatccacg tcagcatctg ttacttcacg
    36601 gtcttgtttt tcaacaacta gatctttata ttgtcctaat tttacttctg gtttcactgt
    36661 tacttcagca gtgattaccc agtcttgacc tttttccatg ctttcaacat cgatttttgg
    36721 ttgagaaaca ggatcgatgc cagcttcttt gacagcagct tcataagctt ctggtaatac
    36781 agcattcaat gcatcttcat ataaagcttc ttcaccgtac atacggttga atacttgacg
    36841 agaaactttc cctttacgga atccaggtac gttcaagctt tttttcactt tattaaacgc
    36901 agttgttaat cctttttgga tttcgtcttg cgcaatcgta aattttaaaa caccatcatt
    36961 cgtgcctttt ttttcaaatg ttgcagtcat ttaattccct ccgagtttag aaattcattt
    37021 tatacatcaa aaacgtttca tgcatacctt taaatagtac actaaccctt tcaaattgta
    37081 aacatattga atggatagaa tccttgtttt tcataacatt tttatctttt tcactgataa
    37141 aatctaatgg aagaagatca tttgctgcaa aattttttct ctttttttta aaaaatcttg
    37201 tttttcatct tctgtacctt catacatcgt ttttcctgta cacgcctcta cagtcagttg
    37261 aaaccagcgc ttcgggtctt cgatgtatgt atcatagaca ggataaacaa ttgcagattg
    37321 caacgtgaat tcttctttta acacggaact aagcagcgca tcttcattcc cgtaacgatc
    37381 tgaaaataca cataattgct ggtaacttgc ctgctgctgc ggctttggca gatcttttgg
    37441 tatgactttg actaactttt cttcaatcgt caaatagaaa acaggatggc attcgttcaa
    37501 ttgcctaagt gtctccagta attttgccct tgctaaaata tggacctctg gcgatacaat
    37561 aagtttactc gctgtttgga taaactcatg ataaggaagc tgttcgatct catcaataga
    37621 cgcaagctga cgtgcaggtt ccaacgaagg aagttcctcc gatttattgt ggagtgcctt
    37681 gatcttctgc ctctccattt gtccggataa ttcttctgca aattggattt tttcaatgac
    37741 ccgctgctcg aaagcttcat aaaaatctgt acttgctatc aattttctag catataaaaa
    37801 atcttgtgta ctgattaaca agtcaaaata aaattcagca aactcctcat tttgaagata
    37861 ctgtttttca tgcaagagtg cttgcttcaa tgcttctttt ttctcgtcca actcgtaaag
    37921 acaaaaaaca agcaggctat tagcctcaaa gctttctttc aactcgtaag ctcgttgaaa
    37981 taattctttt gcctgctgat attgctggtt tgctagtgct tgttgtgcca ctcgcattaa
    38041 attctcatat ttttctggaa aatcaatcgg cttcacgcag tgtcctcctc ttgctcatat
    38101 tcagctcatg ttcaatagta gcaaaacaaa aaaagcatga caattaaaaa taactgaagc
    38161 accctctaaa agctagattt tagatctgac ttttagaagg tgctttcaac tgttactgct
    38221 ttttattgct catcagctgt tgacttcctg gttgaacgct ttgatcagat tgatcgtaac
    38281 aacacttgta ttagtgaaaa aatcgcccag atgttgcttt ttctgattaa agactgctgg
    38341 aagataccct aacatcagca aaggaaattt tagaatgaac cggcaagcac cttctctaac
    38401 taaaacggtt gaccagctaa gttcttcttc atcaaagctg atgactcgaa taccaaagat
    38461 cattttccca atcgtttggc catgattgaa tttcgtcaat aaaataaaat acgctagata
    38521 aataagtaag gctgtgaatc cgtagagact cagataagaa tctgaaaaat taagccaacc
    38581 tagatttttg gcaataccaa gtgttaaacg cgtaatagct ccgatacaca aaagatcgac
    38641 caagaaggca aacattcgga taaaaaaacc tgcatagaaa tacttaggaa aatcatttgc
    38701 ttttggcggt tcatttcttg tgtccgtata ctttttccat ttacgttgtt tctttttgat
    38761 ttcttcgggc gtcaaaggct ctctttcaaa agagctcagt accttttggg aaaagttgga
    38821 gtcaggtcct acagcaggct gctgttgctt atctttttct tgttccttat tttcatttga
    38881 aagctctgac atgcttactc acctccgtaa taatacattg cttttggtga ttccgctgtc
    38941 cctagattct caagaacgga taagatctga ctagtctcag aaggcttcaa tccctggaat
    39001 tctgctagtt tacttcctaa ccatgtacta gcaaacccag atggcgtgga agaatattct
    39061 actagttccg catcttcaag ctgttgttcc tttcgtatag cttttaaagc atcttcagga
    39121 aatcccaatt catcgactaa acctacttct tttgcttgga caccatcata aatccttcca
    39181 tcagcaattt ttttgacttc ttcttcagat ttattccgtc cctcgctgac gattgctaca
    39241 aaacgactat atgcgctgtc gatatatgct tgaagcaccg cttcttcttc ttttgtctct
    39301 ggtcgcgttc ctgaacccat atctttcaac gctccgcttt taactgttgt atcttccaca
    39361 cccagttttt ctagaagtcc tgaataattc aatcctgaca tgatcacacc aattgagccg
    39421 gtcactgttt cttctgttgc aaagatttta tctgcttgag cagaaatata gtagccaccg
    39481 ctagctgcca tgtttttcat gctgacatac attgggatat catgttcttt acgaatcgta
    39541 tccaatttct tagcgatttc cgcactttcg tagacaccgc caccaggaga atttacttct
    39601 aaaaagatac ctttgactgt tggatcttct tcaatcgcct tcagttgttc cataaaattt
    39661 ttatgattgt aaccttcaga agcaaataaa cctgaagacc ctcccgcagc aatcgttcca
    39721 tctactgata attttacgat tttttgcgta ctgtctccct cttccaacac atttggagct
    39781 agttcttcat ccccatataa ccaactgttc aatccctcaa tttgatcgtt ttcctgaggc
    39841 ttagtcaaac tagctgaaac taacgaaacc acaaataatc ctgcagcaat cagaactgct
    39901 gcccaacgtc ttttattcat tctttctcct ttctaataca agttttttat gacgatcaca
    39961 gtttctgact gctcagaagt gtcgaaccgc tctgcttttt cttcccgcgc atacccggaa
    40021 aacgactctt ttgttaattc atcttctacc gtaaactcac gagcttgagc aacttccaag
    40081 gcatcaggtg cgatttcttg gatgctatcc cagccagtat ctaaaaatat tttcgtatca
    40141 tctgatacac cagctgatgc ttcgaatttg gacaattgtt tttttaacat tcccagtgtc
    40201 atgatctcaa tttttgaatc catttttact cctcctctat ccgattactt tctattgtac
    40261 cgaactcctg aaaaagatga tagataaaaa cccattattt tttgacataa aaaggacatt
    40321 tgacaaagaa tttgatatat accaatttat tttttattct ttttttgttg acaagaacat
    40381 tcgcaaaagg ttatgatttt aaatgtttcc agataaaaaa caaaaaggag gatagttata
    40441 ccttttagga tagcgccagg tctgtgtaaa cagatgacga ggagagggtt tatcgaaaga
    40501 ttcggcggat ggccctaggg actgcactct acagaaaatc cacaaaaaat gtctgcaaag
    40561 ataaaacaaa aggattttcc tgcagctgga agcattcata cgaattcatt atagaaagta
    40621 ggatgttttt tatgtgcgga attgttggaa tgattggatt aaaaaatgta acaccaggat
    40681 tgattgacgg tctagaaaaa ttagaatacc gtggttatga ttcagctggt atctttgtct
    40741 cagatggcac aactgattat ctggtcaaag cacaaggcag aattcaaaat ttgaaaaaca
    40801 aaataaatat tgatactaca ggaaatatag gtattggtca tacacgatgg gcaactcacg
    40861 ggcaaccttc tgaagaaaac gcccatccac atacttccca aagtggacgc ttcgtgctcg
    40921 ttcacaacgg cgtaatcgaa aactttgaag aacttaaaat tgcttattta gcaaatgacc
    40981 actttattgg tgagaccgat actgagatta tcgctcatct aattgaaact ttcgcgaagg
    41041 atactacaac gcaagaggcg tttttaaaag ctttgcgggt catcaaaggt tcttacgctt
    41101 tcgctttgat tgatcggaca gcacctgatg ttatttacgt cgctaaaaat aaaagtccac
    41161 tattaatcgg actcggcgat ggattcaatg tgattgccag cgatgcaatg gctatgcttg
    41221 ctcatacgaa ggaattcgtt gagattgaag atgaagagat ggttaccgtc acatcagaaa
    41281 aagttattat tcaaaatttt gcaggtgaca tcgtagaacg ttcttcattc gaagcacaag
    41341 tagatgcttc agatatcgag aaaggtacct atccttttta tatgctgaaa gaaatcgacg
    41401 aacagcctat tatcatgcgt cgtatcgctc aaaaatacgt aacagaagac aatcgtgtct
    41461 ctcttgatca aaagctggtc gatacattgt ctgatagcga tcgaatctat atcgttgctt
    41521 gcggaactag ttaccatgcg gggttagcag gtaaacagac tttggaaaaa ttgacacaga
    41581 ttcctgttga ggttcattta gccagtgaat ttggctataa cacacctctt ctttcaaaaa
    41641 aaccattctt tattttcttg agtcaaagtg gcgaaacagc agacagccgc caagtgctgg
    41701 taaaaatcaa ccgtctcggc tacccttcac ttacgattac aaatgttgct ggttctactc
    41761 tttcgcggga agcatccttt acactgctat tgcatgctgg acccgaaatc gcagtagcat
    41821 caacgaaagc ttatactgca caaatagctg tactaacttt attagccaaa gctatcggtg
    41881 ataaaaaaga atttgaaact tctcttgtat tcgatatcac tcatgaattg agtttagttg
    41941 ctaatgcgat ggaatcggtc atcgcccaaa aagattattt agaagagttg gcagaagtat
    42001 atctcagcga tacaagaaat gccttttaca ttggacgtgg tgctgactac aacgtttctc
    42061 ttgaagctgc tttgaaattg aaagaaatca gttatatcca ggcagaaggt tttgccgctg
    42121 gcgaattgaa acatggaacg attgctttga tcgaagaagg aacaccagtg atcggaatca
    42181 tcagtgaaga agtgactggt gcgcatactc gaggaaacct gaaagaagtc gaaagccgtg
    42241 gcgctaaaac actagttatt gtctcagagg gattagaaaa ggaaagtgac cagctggtgc
    42301 taccaactgt ccacccttat ctaactactc taaccacagt cgtaccgact caattacttg
    42361 catattacgc aacgctatta cggggattcg acgttgacaa accacgtaat ttagcgaaat
    42421 cagtgacagt agaataataa aagaacaagg accagtgtca gacatctgac actggtcctt
    42481 gttcttttat tttttatgaa aatatctctt aatccagtcc gatttcttct ttgactactg
    42541 ccgcgatttt atcgacatag taattaactt tctcatcagt aggcgcttct gccatcactc
    42601 gaagtaatgg ttctgtaccg gaaggacgaa ctaggattct tccttctgat cccatttcag
    42661 cttctgcctc ttcaatcact tttttgattg ccggaacatc catcgcaccg tttttatcac
    42721 ttacgcggat attcactaat ttttgcggat agattgttac ctctgctgca agctctgata
    42781 atttcttacc tgtctgtttc atgatattca gtaactgaat tcctgaaagc atcccatctc
    42841 cagttgtgtt aaaatctaag aaaatcatgt gcccagactg ctcgccgcca aagttataat
    42901 cgtttttgcg catttcttct acaacgtaac gatcaccaac ttgtgtaacg acatctttca
    42961 aaccgattcc ttccaccgct ttgtggaatc ctaagttact catgacagtc gtaacgatcg
    43021 tatctttttt caatcgattt ttttctgcca agtatttagc acagataaac atgattttat
    43081 caccgtcgac aatgtttcca agttcatcca ccgcaataat acgatcgcca tcgccatcga
    43141 aagctagtcc agcatctgct cctttttcaa cgaccatctc agctaaacgt tctggatggg
    43201 tagagcctac gccgtcattg atatttaacc cgtctggatt tgtgcccatt gtataaaaat
    43261 ctgtttcaag atcggcaaac aaacgattaa cacttgttga agttgctccg tttgctgcat
    43321 cgacacaaat ggtcaaaccg gaaaggtcac cgttgatcgt ttgtacaagg aattgagaat
    43381 atttcaataa gccttctgga aattcttcta cagttcccaa tccttcagct gatggacgag
    43441 gcaattcatc cacttcagca tctaataatg cttcaatttc tagctcttgg tcatctacta
    43501 gtttaaaacc atctgcaccg aaaaatttga ttccattatc ttgtgctgga ttatgagaag
    43561 cagaaatcat gacccctgcg cttgcttttt gcaaacgtgt cagataagca acacctggtg
    43621 tagagatcac acctagctgg aacacttcga tacccaccga taaaagtcct gaaatcagcg
    43681 cttcttctaa catttgacct gagattcttg tatcccgccc tactaacacg cgtgggcgtt
    43741 ttccttcttc ttcatgctgg cttaggacat aacctccgca ccgtcccagc ttaaatgcaa
    43801 gttctggcgt aagttccttg ttggcttcac cgcgtacgcc gtctgttcca aaatatttac
    43861 ccatagttgt aaaattactc ctttaactta attttctgag gaatttgttc tgctcatttg
    43921 tgttgattcg cttgtttctg atgtttcttc tgtacttgtg gtcgagctgc ttgtcccaga
    43981 ttccgaactg gaagaaatgg ttgttgtcga tggttccgtt cctgaatcag cagatgaaat
    44041 acttctactc gtacttgtat tttcttgtgt ccgactgctc gtcgaagcag agctactgct
    44101 tgacgtttgc aacacgggtg taatctccac actaactgat tcgggcttga tacttaaccc
    44161 ctcttctact ggtatttcaa ttttacgagt tgttcgatga ttgatacctg agacattgat
    44221 cggtacagca atactgtcac cgatcgatgc aagcaaatcg ctagagccgc ttacttctgc
    44281 ttccagtttt gaaaaactga aatcatagct ttctaccccg gcagctggtg ttccttgctg
    44341 tatcccataa agtcgtaccg acttgcttgg cttgatcgaa tcagctctca ctgttacttg
    44401 cactggatca gagacgatac ttaatacttc ccctgctgca ttcagcgcct gtattgggac
    44461 ctcactatta atcccatcat ctgtgaccat cgaagcgtcc acatcagcta ctactcgttt
    44521 gatttctgcc aatgttttgt cacctgtagt gatagagact tttttaggac taacggaagt
    44581 atcatcaagt tcatatccag atggtgtgaa cgttgaagga atcaacgttt ccacatcgaa
    44641 atcttttatt acctttttct caaccgttac tgtaatagtc gatggttcga tctttgctgt
    44701 gacagcactg ctcaaatttt gaatttttag cggaacttca tgtgttcctt cgcccagctt
    44761 agtgatatct gctgtgacgc ggaacatccg tgtatcttcg tttgcctctg cattcaactg
    44821 aactcggttt gcactggaaa gtttgacagt cactgcattt tcatatccat ggatatagta
    44881 gcgctttgaa tcataagaaa tcttgatcgg cacccccgta actgtttgat tatacgcttc
    44941 atttccagaa agcgtatttg gaacggactg gccatttgca ttgaagtaca gcgcaatact
    45001 gaacagcaat gcaataaaac tgtaaagaat gcttgtccgt ttctcttttg agatcatttg
    45061 cgatcccctc ccttagtcat accgtctagg aaagattgaa tcacgttttt cttgtttttt
    45121 gttttctctt cagcaattag ttctctacgc aagattgcca aatattcttg ctgggataag
    45181 ccagccatca gttcattatc taacgtgatg ctgacgtccc cggtttcttc agagacaacg
    45241 atggtaatcg cgtcactgac ttcgcttata ccgacagctg cccggtgtcg agtcccgaat
    45301 tctttaggga tcaacatact ttctgataga ggaagatagg cgcttgctac tgcgatcttt
    45361 ccttctttta caataactgc accgtcatgc agcggtgtat taggaataaa gatattgatc
    45421 agcagctccc cagtgatatc tgcatctaaa gcaatccctg tctcaatata ctcatctaat
    45481 ccagtatgac gttcgatagt gatcaacgca ccgatttttc gcttggacat atattggatg
    45541 gctttgtcaa aagacaagat catcttctca tcttcctgct gttcgctttt tgattgtttg
    45601 aaaagcgaac tgcgtccaag atgttccagt cctctccgga tttccggctg aaaaatcacg
    45661 atagcagcta tcaccccgta cgtaatgact tggttcatca gccaagacaa ggtgtgcaga
    45721 ccaatgattt ccgctacgat tcggataaca ataaaaatag ctacaccttt cagaagctga
    45781 atcgcttttg tgcctcgcag cagttggatc agtttgtata caagatacca gacaaccaga
    45841 atatcaagta tgttcaccaa aaaattcaga gagaacaagt caccggaaaa catttgctgc
    45901 caatagtcca aattaaaaag ttccccgatt tgaaatgaca taaaaagcct ctcttctctt
    45961 ttgagatttc ctctctagta tatcatatgt tttaatttta gaggctgata tgctcgtatt
    46021 tttcttgaga aaaacgcata attttcaaga aaattgcaag tatgcgtttt atttttctct
    46081 gcaataaata tttttaaact tcagagaatt attcattata ttttttctgt tatttttcct
    46141 ttttttcttt tgtagcttgt tccatttttt tacgtcgttc tgctctggca gctcttctag
    46201 cagctcttct ttcttctgct tcaaggtccg tcgttttttc ttttctagtc ttaacgggta
    46261 catcgataga ttcctctggt tcaagtcgtt tcttgatttt ttctaattct cccgtcagtg
    46321 cagcatagtt gtaaaaacgt gttttagcgt cgtggacagt cttttcaaat aaagcttttg
    46381 caagatttgg atttgcgtta tctagcgagg aaaagcgaac ttgtttcctc atgaaatcag
    46441 gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat tgggttcttg tttttttcga
    46501 ccattgtagg gttatatcga tataatgacc aataaccaga agaaacagct tcttttgctt
    46561 ctttaagcga ttctttcatt ccgccaagca agccatgtgt gatacaaggc gtataggcaa
    46621 taatcagaga aggaccagga tacttttctg cttcttcaaa tgccttgatc gtttgcattt
    46681 gattggcacc tgaagcaatt tgcgccacat aaacatttcc atatgtcatc gccatcattc
    46741 ctagatcttt ctttgaagca tactttccac tagccgaaaa tttagcgatt gccgaagctg
    46801 gtgttgcttt tgaggtttga ccgccagtat tggaatagac ttcgttatcc aaaacaagga
    46861 tattcacgtc tgctccgctg gcaagtacat gatcgatccc gccaaaacca atgtcgtaag
    46921 cccatccgtc tccaccaatc atccattggc tgttttttac gaatagatcc tttctcttgt
    46981 atatatcctc cagttcaggg aaaattgatc gttcgctttc gatcgcagct tgcagttttg
    47041 ctgctctttg ctgcgttcct tcactctcaa acatgtgtac taaccagtct tccatcaatt
    47101 ctcgtagttc ttctgatact tttggcaata cttctttgat tgaacttgcc aaagcctcgc
    47161 gacgagtctg tgccgctaga agcataccat aaccaaattc agcattatct tccaataaag
    47221 aatttgacca tgcaggccct tgaccacatt cattggtcgt ataaggagaa gcaggagaag
    47281 caccgcccca aatagaagaa cagcctgtcg cattcgcgat catcattcga tcaccgaaca
    47341 tttgtgtcaa taattttaca taaggtgttt cgccacagcc tgagcaagcg cccgagaatt
    47401 caagaagcgg ttgattgaat tgtgtagaca agacagtatt ctttcctttg actggatttg
    47461 ctttttgtct taatgtcatt gcaaaagccc aattcacagc ttgttctttc tgttcttcat
    47521 aaggcttcat cactaaagct ttttcttttg cgggacaagc ctctacacac agaccacaac
    47581 ctgtacagtc ttccactgaa acttggatac ggtattttac gccgtctgcg cctcgcattt
    47641 ctctcacgat aaatccttct ggcgcttctt ccatttcctc ttcatctgct aaaaatggac
    47701 ggatggcagc atgaggacaa acaaaggcac attcattaca catcgtacag cgatcactaa
    47761 tccactcagg tacttctaaa gcgacgcccc gcttttccat agaagccgtt cctaaaggca
    47821 tttcgccagt tgtcattcca tttgctacaa gtgtaccaac agagagttga tttccttcct
    47881 gtgcattcac tggttcaagt atttcttgta tataaccagt gttcctttta ttgatttttt
    47941 caggcatctc caacgttctc caatggtctg ggatcgcgac ttgatgaagc agttcggtcg
    48001 tccgatcgat tgcttgtatg tttttttcta cgatagccat tgatttatgt ccatagcttt
    48061 tcagggcttc ttcttttagc agcggaagca cctcatcaaa aggaatgatg tcagctaatt
    48121 taaaaaaagc cgtttccatt gccgtattga tccggcgtcc caaaccgact tcttgggcca
    48181 atctcatggc attgatcgta tagaatctaa tgttattttc agccaagtaa cgttttaatt
    48241 ttaagggcag atgcgtttct aattgttcgt cgctccaaag agtattcaat aaaaaaatgc
    48301 cacctggctt caatcctttg accaagtcat agctatgcag gtaagctggt gtgtgacagg
    48361 caacaaggtc cgcatgctcg acaagatacg ctgaacgtat cggcgtatct ccaaaacgaa
    48421 gatgagagac agtcagaccg ccagattttt tcgaatcata ataaaaatag ccttgcgcat
    48481 atttatcggt gtgatctcca ataatcttga tagctgattt atttgctcca actgttccgt
    48541 cagatccaaa tccccaaaac ttggcctgga atgtttgcgg ttctgtcaaa ttcagacttt
    48601 cctttggttc caaagattga taagtcacat catccacgat ccctatggta aaccgttttt
    48661 tgcgtatgct tgggtctttt ttcaattcat caaaaactgc tgagatttgg tcgggagtca
    48721 catctttaga ccccaatccg tagcgaccac caataacagc cgggcgaagt tcagaatcat
    48781 ataacgcact ttgaacgtct aataagagag gttctccacc tgcccctggt tctttacttc
    48841 gatcaagaac agcaattgtt tttactgtat gatgcaactt ttgcacgaat gtttccactg
    48901 gaaaaggacg ataaagatgg atattcaaaa aacctgtttt ccgtccgttt gcattcaagt
    48961 aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat agaaacaatg acttcttccg
    49021 catcgtctgc tccgtaataa gtcaccaagt cataagaagt tcctcgtaat cggttgatct
    49081 ctttcatata tttttgaacg atttcaggta atttatcata ataggggttg atcgtttccc
    49141 gttgttgaaa atggatgtct ggattctggt tcgtaccact aacagtcgga tgattgggat
    49201 tcatccctcg tttacgaaat gaagctaatt tctcctgatt gatcagagga gctaattctt
    49261 catattccaa aacttcgatt ttttgaatct cgtgactcgt acggaatcca tcaaagaaat
    49321 tcaaaaaagg gacttctcct tcaatagaag caagatgggc aacaggtgct aaatccatca
    49381 cttcttgtac actgctttca gctaacatag caaatcctgt ttgtcttgca gccatcacgt
    49441 ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac tgcccgacta gcaacgtgga
    49501 aaacacttgg cagtagttcc ccagcaatct tgtacatatt cggtatcatc aaaagcagcc
    49561 cttgtgaagc ggtatatgta gttgtcagtg caccagtttt caatgatcca tggaccacac
    49621 cagctgctcc tgcttcggat tgcatttcta ctacttttac tggttgaccg aatacgtttt
    49681 cttttcctgc tgctgaccat tgatctacta attcagccat ggtcgaactg ggtgttattg
    49741 gatatattgc agcaatctcg gtaaatgcat aagaaatata tgcggctgcc gtattgccat
    49801 ccattgtttt catttttcgc atgattcatc atccttgttc atattctctc ttattatctg
    49861 ttccattata acgtaaaaca tgccattttt ttcttttatt tataaaaata ttttacatgt
    49921 atctatttga attggtcatc taatttttag acaaacagtc taaatcgttg cctttttttg
    49981 tcagacatgt ataaactata agcgaaagag gtgttttaac atggatatat cagtgattga
    50041 tgcaacgaaa acaaatacac aaaaaggaat cctttatggt tcatcgaatg ctcctaaaaa
    50101 aatggtcgaa ttcatcaact tagcttgtcc gtattgccga caatggtttg aagaatctta
    50161 tgagctatta gaagaagcag tccaaagcgg gcaattgcag cgagtgatca aattgttcga
    50221 taaagaaaaa gaaagcttac agcgagggaa cgtgatgcac cggtatctca caatcagcga
    50281 tggccaaaaa gcgatcaaag agatcaaaca aatattcgat actcaagacg agtggaaaca
    50341 tctttctctc caagaagtag cggattttgc agtagataaa ctaaagctga cagaacaaaa
    50401 agacgaacag ctgagccaag ctgtcatcaa cgaagctgag caagcacata ttcgatttgt
    50461 tccaactgtc atcttgggta aagaaatctt tgatgaatct atttcaatag aggaattaaa
    50521 agaattgatc caaacaaaat aaaaaaataa ggagcgtggg acaaaagtaa agaacacttt
    50581 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    50641 ggagttaaac gcttctgtcc cagcctcctt attccgaata aatggtgtcc aaaagcttgc
    50701 atctgccaga ttatctcatt tcttatgaca agctaagcaa attatctcca ccaaataatt
    50761 tattcatatt tttgacttgc gcatactaac taattcttaa attttcatac aaaatttctc
    50821 aatttccctt aacgagtaat atttatgtac ggtgattctc actagtatcc caatcacttt
    50881 ttaagttatc ccgatttcaa ttctacttca aaaatagttg cttttatgta tgctgttagt
    50941 tgattagatg gtcatttgtt gagctaggtc gtttatttta aacaagttgt ttctttagct
    51001 tatacctatc tcgtctacca aacgcaagat ggcaaacaca aatgcatacg catctgtatt
    51061 tgccactttg attcgtataa agctaacaac tattaactcc tctcagctaa tagttgctct
    51121 cttttttatt cagattcatt tttgctgatc acagcctagt atttcaatgg ttttgaacac
    51181 taaaccaaat tgttccatta caacattcac tggctgatga aatggattag tagatttcga
    51241 ttattcaaag cgattttcta ttggtggatc gtgttcccaa ctaataagac ggattccaaa
    51301 cctatcgtac agatcttcta aaccacttat aaattttgca cctatttcag gtgttttatt
    51361 gcgtggatat tctattgtta cgccattaaa tggataccaa ttaggattag gctctctttt
    51421 tttctgtaca tctcccatag aatagttagc actttctggg acataatata ttcttcgacc
    51481 atcctctaat tcatctaata agatatttcg tgatcgtcta tcacttgcta aatgtagacg
    51541 ccacgtgcga taccatgcca tgctacctgc atctgcagaa aatccatcaa ataatgcaac
    51601 aattgtatct tctatcacaa tcctttcccc atctacttca tattctaatc taaaatcaaa
    51661 ctcccctcgg gtaatttctg gtcttggtgg cttaggaccc aatattattc tacttaaaac
    51721 cgcattcgtt cccagatgaa acacagctat aacaacaata atgattaata ttttgtttct
    51781 atttgataaa tttctcatta ttcgcacatc acctctacat tctcacatat tagttcgtaa
    51841 tactccttta atatcaaaat atctactggt cgtaataata ttcgctatga attcctacta
    51901 ctcgtataag aaaggccaaa tcatcagctt ttacttgctg atgatttggc ttgtttctat
    51961 ttatcgtaat tgttttctaa tcaccaaaat tgttaacaat cggttcagat atttcccagt
    52021 tgattaaggt aattccgtat tgtgtcaaaa cttcttgcgc ttctccgaaa ttaagtacag
    52081 ttcttatgta tccactttct cctaatataa agtctacctc tcttttaaaa ccttcctcga
    52141 gatttctaag ggctatatgt ggttttaatg acattgattg tacattttcc cccatataat
    52201 attgcgcact tcctcgacta aaatagattc ctagatc
//
LOCUS       DAXLPQ010000012        51314 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.012, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000012 DAXLPQ010000000
VERSION     DAXLPQ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.012"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            290..1135
                     /locus_tag="ACF3UO_000941"
     CDS             290..1135
                     /locus_tag="ACF3UO_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3656986.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="ACF3UO_000942"
     CDS             1416..2636
                     /locus_tag="ACF3UO_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFD3656987.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="ACF3UO_000943"
     CDS             2633..5353
                     /locus_tag="ACF3UO_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3656988.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="ACF3UO_000944"
     CDS             5337..6281
                     /locus_tag="ACF3UO_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3656989.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="ACF3UO_000945"
     CDS             complement(6350..7360)
                     /locus_tag="ACF3UO_000945"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3656990.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="ACF3UO_000946"
     CDS             complement(7540..7884)
                     /locus_tag="ACF3UO_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFD3656991.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="ACF3UO_000947"
     CDS             complement(7877..8311)
                     /locus_tag="ACF3UO_000947"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFD3656992.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="ACF3UO_000948"
     CDS             8449..9186
                     /locus_tag="ACF3UO_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3656993.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="ACF3UO_000949"
     CDS             9179..10390
                     /locus_tag="ACF3UO_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3656994.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="ACF3UO_000950"
     CDS             10594..11376
                     /locus_tag="ACF3UO_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFD3656995.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="ACF3UO_000951"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="ACF3UO_000951"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFD3656996.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACF3UO_000952"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACF3UO_000952"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFD3656997.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="comGA"
                     /locus_tag="ACF3UO_000953"
     CDS             14092..15021
                     /gene="comGA"
                     /locus_tag="ACF3UO_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFD3656998.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /gene="comGB"
                     /locus_tag="ACF3UO_000954"
     CDS             14978..16027
                     /gene="comGB"
                     /locus_tag="ACF3UO_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFD3656999.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /gene="comGC"
                     /locus_tag="ACF3UO_000955"
     CDS             16024..16302
                     /gene="comGC"
                     /locus_tag="ACF3UO_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFD3657000.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /gene="comGD"
                     /locus_tag="ACF3UO_000956"
     CDS             16277..16747
                     /gene="comGD"
                     /locus_tag="ACF3UO_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFD3657001.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16719..17066
                     /locus_tag="ACF3UO_000957"
     CDS             16719..17066
                     /locus_tag="ACF3UO_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657002.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17029..17454
                     /gene="comGF"
                     /locus_tag="ACF3UO_000958"
     CDS             17029..17454
                     /gene="comGF"
                     /locus_tag="ACF3UO_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFD3657003.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /gene="comGG"
                     /locus_tag="ACF3UO_000959"
     CDS             17426..17785
                     /gene="comGG"
                     /locus_tag="ACF3UO_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFD3657004.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="ACF3UO_000960"
     CDS             17957..18964
                     /locus_tag="ACF3UO_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3657005.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="ACF3UO_000961"
     CDS             18989..20173
                     /locus_tag="ACF3UO_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFD3657006.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACF3UO_000962"
     CDS             complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACF3UO_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFD3657007.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22298..22426)
                     /locus_tag="ACF3UO_000963"
     CDS             complement(22298..22426)
                     /locus_tag="ACF3UO_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657008.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22771..22914)
                     /locus_tag="ACF3UO_000964"
     CDS             complement(22771..22914)
                     /locus_tag="ACF3UO_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFD3657009.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23136..23615)
                     /locus_tag="ACF3UO_000965"
     CDS             complement(23136..23615)
                     /locus_tag="ACF3UO_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3657010.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23688..23972)
                     /locus_tag="ACF3UO_000966"
     CDS             complement(23688..23972)
                     /locus_tag="ACF3UO_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657011.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24050..24244)
                     /gene="ssrS"
                     /locus_tag="ACF3UO_000967"
     ncRNA           complement(24050..24244)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACF3UO_000967"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24316..25602)
                     /locus_tag="ACF3UO_000968"
     CDS             complement(24316..25602)
                     /locus_tag="ACF3UO_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFD3657012.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25740..26411
                     /locus_tag="ACF3UO_000969"
     CDS             25740..26411
                     /locus_tag="ACF3UO_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFD3657013.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26377..26865
                     /locus_tag="ACF3UO_000970"
     CDS             26377..26865
                     /locus_tag="ACF3UO_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFD3657014.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26878..27825
                     /gene="prmA"
                     /locus_tag="ACF3UO_000971"
     CDS             26878..27825
                     /gene="prmA"
                     /locus_tag="ACF3UO_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFD3657015.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27826..28590
                     /locus_tag="ACF3UO_000972"
     CDS             27826..28590
                     /locus_tag="ACF3UO_000972"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFD3657016.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28823..31036
                     /locus_tag="ACF3UO_000973"
     CDS             28823..31036
                     /locus_tag="ACF3UO_000973"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFD3657017.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31047..31493
                     /gene="dtd"
                     /locus_tag="ACF3UO_000974"
     CDS             31047..31493
                     /gene="dtd"
                     /locus_tag="ACF3UO_000974"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFD3657018.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31664..32923
                     /locus_tag="ACF3UO_000975"
     CDS             31664..32923
                     /locus_tag="ACF3UO_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFD3657019.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33012..33959)
                     /locus_tag="ACF3UO_000976"
     CDS             complement(33012..33959)
                     /locus_tag="ACF3UO_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3657020.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34353..35645
                     /gene="hisS"
                     /locus_tag="ACF3UO_000977"
     CDS             34353..35645
                     /gene="hisS"
                     /locus_tag="ACF3UO_000977"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFD3657021.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35660..37429
                     /gene="aspS"
                     /locus_tag="ACF3UO_000978"
     CDS             35660..37429
                     /gene="aspS"
                     /locus_tag="ACF3UO_000978"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFD3657022.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37538..38413
                     /locus_tag="ACF3UO_000979"
     CDS             37538..38413
                     /locus_tag="ACF3UO_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3657023.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38679..40562
                     /locus_tag="ACF3UO_000980"
     CDS             38679..40562
                     /locus_tag="ACF3UO_000980"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFD3657024.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40637..40921)
                     /locus_tag="ACF3UO_000981"
     CDS             complement(40637..40921)
                     /locus_tag="ACF3UO_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFD3657025.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40911..41645)
                     /locus_tag="ACF3UO_000982"
     CDS             complement(40911..41645)
                     /locus_tag="ACF3UO_000982"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFD3657026.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41774..42397
                     /locus_tag="ACF3UO_000983"
     CDS             41774..42397
                     /locus_tag="ACF3UO_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFD3657027.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42589..43710
                     /locus_tag="ACF3UO_000984"
     CDS             42589..43710
                     /locus_tag="ACF3UO_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFD3657028.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43717..46845
                     /locus_tag="ACF3UO_000985"
     CDS             43717..46845
                     /locus_tag="ACF3UO_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3657029.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46864..50058
                     /locus_tag="ACF3UO_000986"
     CDS             46864..50058
                     /locus_tag="ACF3UO_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFD3657030.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50204..50911)
                     /locus_tag="ACF3UO_000987"
     CDS             complement(50204..50911)
                     /locus_tag="ACF3UO_000987"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3657031.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16802 a         8956 c        10641 g        14915 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 ttgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatctcaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggctt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cggaccagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg aaactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acggtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatac cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccctggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttat tttacttgaa ctcattgact gttttccctt tattttaaac
    23041 attataaaga ccgatgagtg cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa
    23101 aaaaacctgc cgatagttgg caggtcgtct acgtgttaag ctttggtgtg gtctttagct
    23161 ggcaattggt tttctaaatc agttcggaca acaagcacat cgcaagctgc gtttctaata
    23221 acatattcag aaacagaacc aataaataaa cgttctacag cattcaatcc tgtggctcct
    23281 aacataatca aatctacttg attatcttct gggatttctc tggcaataat ttgttttggt
    23341 gagccatatt ctacgacaga ggttacatta ttcaagccag ctttcttcgc attgctttca
    23401 taatctgcca atgtttgctt tgccatttca gtagcttgtt ctgcaagcat tccatcaaag
    23461 gatgaaacgg tttggaaaga acgtgtgtca atgacatgtg ctaatagaag ttctccgtta
    23521 tttcggatag ctacattgac cgccttttta aaagctaatt cagcttcatc agaaccatct
    23581 acggcaacca tgattttttt gtattgttgt aacataagca ttcactcctc aagtcaatcg
    23641 tattgtactc ttttattgta gaacacttta gggaaaaaga gaattattta ctgctttggt
    23701 tcagcaattt tttttgcaaa tcggatactg aaggtggcag aaacaataat tacgatcagt
    23761 aaaaagacca aggcaataaa gcgttgattg aaaaaagctg ttaaaatacc cattacgcct
    23821 aaaacagcat atgcagcacc gtaaaattgt aggaatcctt gatttttatc atttttgttg
    23881 atcaatacaa aaaagatatc ctgtttatta aataaataat agctaacgaa taataatact
    23941 aaagtggcga taatcattaa aatcctaatc atgaacaaat cctccaaaat aagcaacaaa
    24001 tagaaaaagc aatttgccaa gagcaaattg ctttattctt taaaagatgg taatctccgt
    24061 taatgccgtt gtttgtcctg tagtattgat cccgcgaatt caagcaggtg ggtcccatgg
    24121 tcgtagcttc gaactaccaa atgataaggc atgttaccag cagtgacaca agacgggtcc
    24181 caagatatca ataaaaatgt tcggtcaaca cacaaagagg acaattcgaa catcacagat
    24241 ttcccacctc tatagtagca tatgaattta aaaagagcaa tgagagagct cgcagaaaca
    24301 gaaccgtttt cttgtctagt tttttggagg atgctttttc cactctttta tacggtaata
    24361 ctgttgaccc agagcctgtt catatttccc tgtatctttt ggctgataat actgagcatt
    24421 cttcagttta tctggtaaat attgctgatt gacccaagcc tgatcaaaat gatgaggata
    24481 ctgataaccc acgccacggt tgagtgattt cgcacctttg taatggctat ctctcaaatg
    24541 atcaggaaca tctccagctt tgccctctcg aatatcagca agtgctgcat ctaatgccat
    24601 gtaggcagaa ttggattttg gcgacaagca aagatcgacg acgacgtctg ctagtgggat
    24661 acgtgcctca ggcaatccca atttttcagc agctaataca gcgttcactg tacgagccgc
    24721 agcagcagga ttacctaaac ctatatcttc ataaccgata accatcagac gccggcaaat
    24781 acttgccaga tcacctgcct caactaaacg ggcgagataa tgaagtgcag catccacatc
    24841 acttccacga atcgattttt gaaaagccga aataacgtca taatgagcat ctccattttt
    24901 gtcatgggta agagcttttc tttggacaca ttcttcaatg atcgacagtg taagatgaat
    24961 ccttccttct ttatctgaag gagtcgatag tgtagccagt tccagcccat tcaatgcact
    25021 ccgcaaatcg ccgttcgttg cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat
    25081 tgcttgttgt ccaaggccgc gttctttatc ccttaaagca tgttcgactg ccaactggat
    25141 gtcttgttct gttaatggtt tgacttcaaa gatctgtgta cggctgcgga tcgctggatt
    25201 gatggtaata taaggattct cagtagtcgc tccgatcaag atgattcggc cactttctaa
    25261 atgaggaagc agaaaatcct gttttgtttt atctaatcgg tgtacttcat ccaataagag
    25321 gatcactgta ccactcattt ttgcttcttc cgctacaact tgtagatcct tttttgaatc
    25381 tgtagcggcg tttagcatgc gaaatgcata attagtagag ccggcgatcg cacttgcgat
    25441 actcgttttt ccagtaccag gaggtccata tagaatcatg gaagagagca tgcgagcatc
    25501 gaccatgcgg cgtatgattt ttccttcccc gactagatgc tgctgaccaa cgacttcatc
    25561 gatcgttcga ggtctcatgc gataagccaa tggctgttgc ataggatttt cctccttctt
    25621 gtttttacgt cccttaatta tatcatattt agcaagatgc ctagaaagaa cagccttctg
    25681 ttgttttgtt ttcatagctt atccaactaa tattgtgtat gataaagtag gtgagaaaaa
    25741 tgacggataa acaaaagata gatgaatttt tttggaataa aacgacgcca gaagtggcac
    25801 gggatttatt ggggatgtat ttggagcatg acacaccaga aggaagatta gctggatata
    25861 ttgtagacgc ggaagcatac ctaggtccag aagacgaggc cgcccatagc tatggtttaa
    25921 gaagaacacc gcgtgtgcgg gcaatgtatg aaaaaccagg tacgatctac ctttacacga
    25981 tgcatactca tcggattttg aacatcatta ctcagccaga agggattcct caaggagtaa
    26041 tgatacgtgc aatcgaaccc gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa
    26101 aaactggtcc agatatcagc aacggtccgg gaaaattagt ggaagcatta gcaattcctc
    26161 aagaacttta tggtcagtct atagcagata gttcgttacg cttagttttt gagaaaaaaa
    26221 agacaccaaa aaagatcaat gctttgccta gaatcggtat cccaaacaaa ggtgtatgga
    26281 cagaaaagcc gttgcgtttt gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa
    26341 accaaatcga gaaagattgg ggttggagga aagaaaatga aaaagaagga tctattaaca
    26401 tatttagatg aaataattga aaaacaagtg acagactatg atgtagcttt agattgggat
    26461 acaaaaaatc atacgatcga gatcgttgtt cgcttgtttg cagaaaataa agcacaattt
    26521 gagattgatg atgcagaagg gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc
    26581 gtacttcttt ttaatcctca gaaatctgtt tttgatgaac gcaattatct agcagtaatc
    26641 ccttatgaag gaaaaaaagg gttggcaaaa tcagtagctg attctttagt ggaatatcta
    26701 aatgaagtat tagctcaagg gcaaagcgat ttgcttgatt ttttggatga agacgatgac
    26761 gaagctgtat tcgagcttca ctgggataat caacaactag cagaattagt agaagtaaaa
    26821 cagcaaaatg aagcagatac ttatttaccg tacccaagtt attaaggagt gacagatatg
    26881 aaatggaatg aagtaaaagt agaaactgaa agtgaagcag tcgaagcagt tgctaatatt
    26941 ttgatggagg caggggcgag tggtgtcgcg attgaagatt ctttagatgt tgaacatttt
    27001 cagtcggatc aatatggtga gattttagat aaaaatgatt ttacatcgct gaaagaaggc
    27061 gcactagtca tggcttattt tccggaaacg actttcttac cggaaatctt gccttttatc
    27121 aaagatcgta tcacacaatt acctgagttt ggtctagcta ttggaaaaaa taaagtaaca
    27181 gttagtgaag tagaggaaag caactgggca acagcctgga agaaatacta tcatccggtg
    27241 cgtattacgc gaatgctgac ggttgcgcca agctgggaaa actaccagac agaagatcct
    27301 ctagaaaaaa ttatcacact agatcctggt atggcatttg gcacaggcac tcatcccacg
    27361 acttccttga cattgacagc actagaaaca gtcttgcgtg gtggtgaaac attgctagat
    27421 gtgggaactg ggtcgggcgt gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc
    27481 tatgcctttg atttagacga agtagccgtt cgttcggcga aagaaaatat ggatatgaat
    27541 gaaatagcca aagatgtcca tgtatcagct aacgatcttt tgacaggaat cgagattgaa
    27601 agtgatgtaa tcgttgcgaa cattttagca gatatcatct tattgatgat cccagatgct
    27661 tggcgtttac tgaagcaaac aggcacgctg atcgtttcag gaatcattga agagaagaag
    27721 caaatggttc tggatgccat gttagaacaa gggtttatcg tggatcaaat tttccagcaa
    27781 aaagactggt atgcaattat tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt
    27841 ttaaaagaat catatgaatc aaaagactat tttgttttag aaggggaaaa ctatcaccac
    27901 attgtacggg ttatgaggat ggaacccgag gatgaagttt ttttggcatt caatgatcaa
    27961 atagccattg ttgcagaaat cacggagatt actgaagagg ctgtttatct gaaagaaatt
    28021 aaaaaagaag aaaatcaaaa ggaactgcca agttcgatta ccatagcgag tggctatcct
    28081 aaaggggaaa agctggattg gatcgttcag aaatccactg aattaggagc gcaagctttt
    28141 cttggtttcc cggcatcagc ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga
    28201 caacaacggc ttgaaaagat tgctcaagag gcagcggaac aatcccatcg gcagatcgtg
    28261 ccatcagtag agttattgga aacgaaacaa gatttatttg agcggctaga tgattatgac
    28321 gtggtcttgg ttgcttatga ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa
    28381 attcttagtg aaacaaaacc agatagtcga atcttagctg tctttggacc agaaggtgga
    28441 ttatcccgcg atgaagtcga ttattttgta gaacacaaag ggatactttg tggattagga
    28501 ccaagaatcc ttcgtacaga aacagcacct ctttatttat taagtgctgc tagctatcaa
    28561 tgggaattaa tgaatccttc tttcagctaa cgttcttcat taataaaaga gtatcgacag
    28621 aaagaattga aaaaatagtc aacaatttgt ataatagaaa caattattta tacaatggat
    28681 acgaaaaatc gtttgaaaaa gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac
    28741 tgcacggatt ttgggacaat tatcaaacag atatttgtcc cgattcccgt tttaccgaaa
    28801 aaagaaaggg ggatcgattc ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat
    28861 aaagctcgtt agtcaataca tgggtcccga acatgtagca tttgttgaga aagcatgcga
    28921 atacgcgact gctgcacatg acggacagtt tagaaaatca ggcgaaccct acattattca
    28981 tcctatccaa gtcgcaggta tattagcaga tttaaaaatg gatccccata cagtggctac
    29041 aggcttctta catgatgttg ttgaagatac agaaatcact ttagaagatc tgagagaaga
    29101 atttggcgat gacgttgcta tgttagtgga cggcgtaacc aaattaggga aaataaaata
    29161 taaatcccac gaagagcagc tagcagaaaa ccaccgaaag atgctgctag caatggctca
    29221 agatttacga gttatcatgg tcaaattagc tgatagacta cataacatgc gtacgttgaa
    29281 gcacctgcga gaagataagc aaagaaggat cgctcaggaa actttagaaa tctatgcgcc
    29341 tcttgcacat cgtctaggga tcagccggat caaatgggaa ttagaagata cagcacttcg
    29401 ttatctaaat ccaaaacagt attaccgtat cgtccacttg atgcagacga agagagaaga
    29461 acgtgaaaaa tacgtaagtg gtactgttga agatattcga atagcgacag aagagctggg
    29521 gatttttgca gaaatctatg gacggccaaa acacatttat tcaatctatc gtaaaatgaa
    29581 agatcagaaa aagcagttca acgaaattta tgacttgcta gctattcgag tgatcgtaga
    29641 ttcaatcaag gattgttatg ctgtattagg agcaatccac acaaaatgga aaccaatgcc
    29701 cggcagattt aaggattata ttgccatgcc aaaagctaat atgtaccaat ctttgcatac
    29761 taccgtgatc ggtccggcag gaaatccggt agaaattcaa atccgaacac aggaaatgca
    29821 tgaaatcgct gaattcgggg ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa
    29881 agtagaacca gatggtatga cgaaacaatt aagctggttc catgagatac tcgaacttca
    29941 agacgaaagc tatgatgctt ctgaatttat ggaaggcgta aaaggagata tctttagtga
    30001 taaagtctac gtcttcacac caaaaggaga cgttactgag ttaccaaaag gatccggacc
    30061 attggacttt gcatacagta tccatacaga tatcggtaac aaaaccactg gtgcaaaagt
    30121 aaatggcaaa atggtgcagc ttgattacaa attgaaaaac ggagatatca ttgagatcat
    30181 gacttctcca aattcatttg gcccaagtcg cgactggttg aaattagttg ctactagcaa
    30241 agcaagaaat aagatcaaac gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa
    30301 aggccacgaa tccgtggtca aatgtattac agatctagga tttacgccta aagatatttt
    30361 gacgaagaac aaactgcaag aagcactcga tcgttttaat tatcaaacag aagatgatct
    30421 ctatgcagct gtagggtatg gagaagttag ccccttgacg atggccaatc gtctgactga
    30481 aaaagaacgt aaagaacaaa aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa
    30541 tcagccgaaa aaagaacctg acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca
    30601 aggggtagaa aacttactaa ttcgtatcag tcgctgctgt aatccgattc ctggtgatga
    30661 tatcgttggt tatatcacta aaggcagagg gatatccatt catcgtcgag attgtccgaa
    30721 tgttcagcct gacaaaccaa atgtagcaga acgtttgatt gaagtcgaat gggaagatac
    30781 atcgaataca cgaaaagagt atgatgcaga tttggaaatt tacggctata atcgttcagg
    30841 cttattgaat gatgtacttc aaacagtcaa tgcgctaacg aaaaatctca acagcgttga
    30901 agcacggacg aataaagata aaatggcgac gatccatttg acggttggta tccagaattt
    30961 atcccaccta aagagtatcg tggataaaat caaagcagta cctgatgtct acagtgtacg
    31021 ccggacgaat ggataggagg acagatatga gagcagttgt tcaacgggta agtaaagctg
    31081 ctgtgtcagt cgatcagcaa gaaattggaa aaattggcta cggcctactt gttttattag
    31141 gcattcatga aaccgatacg caaaaagatg tggactatct ggtaaaaaaa attgcacaaa
    31201 tgcgtatttt tgaagatgaa caaggaaaaa tgaatattag tgtagaagat gtgggaggac
    31261 aaattttaag tatctctcaa ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa
    31321 gctttgtgga agccgcacga ccagaaacag ctattccttt atacgaatca ttcaatgaag
    31381 gaatcagaag tcgcggcatc acagtcgcta ccggacaatt cggagcagat atgtcggttt
    31441 ctctcgtcaa tgatggacct gtaacgatca ttattgattc taaaaacaaa taaagtaatc
    31501 tggttttcac tagtaaaaac tatgaaacac gtcgcttaag ttagactgat aaactctaac
    31561 ttaagtggct tttttgtctg caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta
    31621 agcttaaatt atacaagtta ttttttatag gaggttgctg aagatgaaag aagtaccagt
    31681 agtagatatc aaaatcacag atttaaaaaa attgtatcaa aaaggataca acatgttgga
    31741 ggagttacgc catgaagcgg acgctcccgt cgtcaaagca aagattttca ataaagaagc
    31801 tatcacgatc tacggatcat cagcagcaaa agtattttat gatccaagga atttcaaacg
    31861 aaaaggtgct atgccaaaat tagtattgaa gacacttttt ggtcaaggtg gagtacagac
    31921 tttggatgga gctgctcatc accatcggaa aaatattttt atggatctaa tgacaccgga
    31981 aagaatggaa gattatcatc gtatcttaga taagaatctg acacaagcac ttgaagcaca
    32041 gcatggtcaa tttgaactat ttgatttaag taagatggtt ttctttacat ctatttgcga
    32101 gtgggcaggt atcaatttat cagcgatttc taaagatgag gtcgaaaaat tagcagaata
    32161 tcaaatctct atgatcagcg gaacgtttac ttctccgatt gatcacataa aaggtgtcga
    32221 gaatcgcaaa aaatcagaaa aatgggcgca aggcttgatt gaagaagctc gacaaaatcc
    32281 tgtggctgga aaagaaaatg tggcattata tgcttttgcc aatgccacag atttagatgg
    32341 tcagctttta cctctggaag tggcagctgt tgaattattg aacatcatcc gtccaacggt
    32401 tgctctaact gtgtgggcgg cattgatggg acatgcactt ttcagtagac cagatttgta
    32461 tcagcaatta aaaaatgact tttcgacgtt acaagatccg tttattcaag aaatgagacg
    32521 ctattatcct ttcttcccaa tgctacctgc gatttcgctg aaagaagtag aagtagatgg
    32581 ttatcgtata ccagaaggca gttgggttat tttagattta tatggaacag accatgatga
    32641 acgaacagtt gaagcgccag attcctttat gatcaaacgg tatgtaggga aagcaaaaga
    32701 tatttcctat aaagaagaat atgagatgat tgcacaaggc gggggaaatt ttcgacaaat
    32761 gcatcgctgt gcaggagaat ggatcactct tcatagtcta cgtgtgtttt ccgatcagct
    32821 agtaaataag tttgagttct ctgtacctga acaagattgg acgattccat tcaatcagtt
    32881 tccgacttat ccgaatagcc gagcgctact ttacaagaat tagattagca taaacttatc
    32941 gaaaaaaagg aagatcaaac agtgctgatc ttcctttttt catattacta taaattgata
    33001 aggtcaattg atcaaaatcc acgaaatgct tcatcaatgg tttgataatc ttcattggat
    33061 aaatgcaaat ctaaagcttg gacattgtca gatacttgct ctggacgctt agctccaggt
    33121 ataactacag acactcgtgg attcttcatg taccaagcta aaacaagttg cgcaggagtg
    33181 gcttggtatc ttttagcaat ggggcgaagt acatcgacag cggttaaaat ttctctgaaa
    33241 cgttctcctt ggaaatctgg atttcttttt cgaggatctc cttcaccaaa ttgtttttcc
    33301 tcaccaagtt catattttcc tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa
    33361 ctgattttgt ttttttcaag ataagggaat aattcttttt cagcctgccg atggatcaaa
    33421 ctgtatttat cttctactac atcgacatat ccatctgcat tcgcttcttt caattgttct
    33481 aacgtgaagt ttgacacacc gactgctcgg atttttcctg cttcttttaa ttcgtgcaat
    33541 gtagcaactg attcattttt tggtgtgctt tcatccggaa agtggatata aaaaatgtcg
    33601 atgtaatcag tttgcagacg ttttagtgca tcttccaccg attgtttgag aaactcagga
    33661 gaattatcaa atgttcgccc tttatttggt acatgagcag cttttgtagc gatgacgaca
    33721 cgtgagcgat catattcttt ttccttcagt acctcgccaa tcagttcttc ggaacggccg
    33781 tttccgtaag cataagcggt atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact
    33841 acttgttttc ctgtctcatc ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt
    33901 gctcctaatc caagctgttc tgcgtagact tgtgaatgtc cgattcttat ttctgccata
    33961 gctgattcct cctttttgtc tagtctaaaa caaaatacca aaaagctaaa ctaaaacgtt
    34021 tttgtgaggg gaaatagtca gatatctctt gactttgaga ctggttttta gtaggttata
    34081 agtaatatcg aatgtcaatg aaagagcgag taagtttttg aaactttaca agagaggatc
    34141 atcgaggctg aaaatgatct aaagtttcat tagcctaaag acactctgga gatggacgag
    34201 tgaaaagccg tcccgcgtac gagcgttatt cgtaagagga aagagaaatc tttcaaaatt
    34261 aggtggtacc gtgtatgaat ttcattcacc cttgttcatg atgaacaagg gtgatttttt
    34321 tatttacata gctaagaaag ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa
    34381 atgatatttt gccaggcgaa tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat
    34441 tattcagaga ttatcagtat aatgaaatgc gtacaccgat ttttgaacac tatgaagtga
    34501 tatcccgaag tgtaggggat acaacggata tcgtttcaaa agagatgtat gatttttatg
    34561 acaaagggga acgccatgtg acgcttcgac cagaaggtac agcaccaatc gttcgttctt
    34621 ttgttgagca taaattgttc ggcccagagt atgcgaaacc gttcaaaact ttttatatgg
    34681 gaccaatgtt tcgctacgaa cgccctcaaa aaggacggtt acgtcaattc catcaaatcg
    34741 gagtagaagc atttggatca gaaaaccctg caactgatgt ggagagcatg gtgatggcac
    34801 ttgatttctt caaacagttg gggatcacgc aaatccggct agtcatcaat tcattaggtg
    34861 ataaagaaac gcgtcaagcc tatcgtcaag cattgatcga ctatctttta ccttttgaat
    34921 cagagctgag tgaagactct aaacgccgcc ttcatgaaaa tccattacgc gtattggaca
    34981 gtaaagacaa acgagatcaa aaatttgtgg cagaagctcc atctatctta gattatctaa
    35041 gcgagcctgc tcaaaaacat tttgataccg ttgtttccat gctggatgca ttggctgttc
    35101 cttatgaaat cgacagtaat atggttcgcg gactagatta ttacacacat acgatttttg
    35161 aaatcatgag tgacgcacca aaaatggggg cacaagcaac gatttgcgca ggcggacgtt
    35221 atgacaatct agtggaagaa ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg
    35281 gtatcgagcg attactcttg actatggagg cagaggaagt agttatccct gcatttaatg
    35341 agttggatgc ttacgtggtc gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg
    35401 tccaagcgat tcgaaacttt ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa
    35461 aagcgcaatt taagacagca gataaagcga atgccaaatt agtattggtg atcggtgaag
    35521 atgagcttgc tagtcaaacg attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt
    35581 ttccattaga agagatatat gaacattttg atgaagtcta tgatgaaatg actttattcg
    35641 agtaggagga aaaaaataaa tggcacaaag aacgatctat tgcggattag tttccgaaca
    35701 acaattagaa caaacagtta cattaaaagg atgggtacaa aaaagacgag accttggggg
    35761 agtaatcttt atcgacctac gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga
    35821 aatcaacaaa gaagcatggg aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt
    35881 gactggggaa gttagaagac gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga
    35941 attcgaagtg attgcaagtg aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca
    36001 aattgaagat gatcaagcaa tcagtgacga aatacgtttg aaatatcgtt atttggatct
    36061 gcgtcgtcca aaaatgacta aaaacatcaa attaagaaat gcgacaacaa aagcgattcg
    36121 tcattattta gatgataatg actttctcga tatcgaaaca ccttacctag ggaaatctac
    36181 accagaaggc gcaagagact acctagttcc ttcacgtgtc catgctggac atttctatgc
    36241 gttgccgcaa tctcctcaat tgtttaaaca attgctgatg aatgctggat tcgaccgtta
    36301 ttatcaaatc gttcgttgtt tccgcgatga agatttacgt ggagaccgtc agcctgaatt
    36361 tacgcaagta gatattgaaa caacgttctt aacagcagaa gaaatccaaa cttacacaga
    36421 gggattgatt gcgaaggtaa tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc
    36481 tcgtatgacc tatgatgaag caatggctcg ctacggcagc gacaaaccgg atacacgttt
    36541 tgatatggaa ttgatcgatc taagcgatac agtcaaagaa gtagaattca aagtcttcca
    36601 aatggctctt gaaaacggcg gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg
    36661 ctactcacga aaagacatgg atcagttagg tcaatatgta ggacaattcg gagctaaggg
    36721 gcttgcatgg ctgaaagtag aagaagacgg attgaaaggt ccaattgcta aattcatggg
    36781 agaagcaaca gaagcaatca ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt
    36841 tggcgcagat aaaagtgaaa tcgtcgctgc tgcattaggt gctatccgga cacgtttagg
    36901 aaaagaatta ggactaattg atgaatcgaa attcaatttc ttatgggtaa ctgattggcc
    36961 acaatttgaa ttttcagaag aagaaggtcg atatgtctct gctcaccatc cattcacgat
    37021 gccaaaagaa gaagatatcc cgttattggc tgaagaccct gcaaaagtct atgcagaagc
    37081 ttatgatatc gtcttgaacg gttatgaatt aggcggaggt tctatccgta ttcatactcg
    37141 tgagcttcaa gaaaaagtac tagaaactct aggctttaca aaagaacaaa tggaagaaca
    37201 atttggtttc ttgttaacag ctttagatta cggattccct ccacatggcg gtattgcatt
    37261 aggattggac cgttttgcaa tgttattagc cggagaagat aatattcgtg aagtcattgc
    37321 ctttcctaaa aacggaaaag cagcagatgt gatgagtgat gcaccaagta tggtttcgcc
    37381 tttacaattg ttcgaattga atattgatgt aacgaatata gaagaatagc cgataaaaag
    37441 gtaaaaagga tttgtcgaat acgcttcttt tgacaacctt gatttaattg aaaaacactt
    37501 tataatgaag ccataacata taaagcgggg cttttccatg aaaaaaacat tcgaaaattg
    37561 ggcttatcat gattacacga ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc
    37621 agtcgcattg aatttctttt atcagccagg acatatttat tcaagtggta ttactggtct
    37681 agctcagatt ttgacgactt tgtcaaaatc actgatagga ttcgaagtac cggtatcaac
    37741 aactttgtat ttactgaata tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa
    37801 gtttacaatt ttcactttta tcacagtcac tttgacctcc ctttgtatcc atattttacc
    37861 ggaaacagtc ctatctaccg atccaatcat ctgtgcgttg tttggggggg ctgtgatggg
    37921 actaggtatt gggctagcgt tgagaaacgg cctatcatcg ggcggtctag atatcgtgag
    37981 tatcacgatt cgtaaaaaaa caggaaagtc gattggttct atttcgatct acttcaatgc
    38041 attgatcgtt tttgttgccg gaattctatt tggctggcaa tatatgtttt acagtacgtt
    38101 gtctattttc gtcagtggaa aagtaactga tgtcgtttat actaaacaaa agaagatgca
    38161 ggtaatgatc gtaacgaaac atccagaaaa agtagtaaat gaaatccaaa actgtatgcg
    38221 tagagggatc acgatcatca atgaagcaga aggtgcttat aagcatgata agcagacagt
    38281 attgatgacg atcgttacac gatacgaact gcctctactt agagaagcaa tgaaagcttc
    38341 tgatccacaa gcttttgtaa gtattgcaga aaacgtccag atacttggtc gtttctatga
    38401 ggatggcatt tagatcgagt ttgacaaaaa ttcatgaaat actgctgtag acagacgttc
    38461 gtttgtctgc agtttttttc taccatagta gaatcagcaa agaaaaactg cttttttatt
    38521 tgaaattttc ttaaagttga aaaaaagcat gtttattttt ttaaatttat gggatgatag
    38581 aaaaaaatag tagagaaagg acacgattct acttgctatt ttcacttaat acccgtatat
    38641 tacgaatgaa aaaagtttat gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa
    38701 aaaacagccg ctacatcact gggtttgatg ggctccgttc attagctgtg gtgggtgtta
    38761 tcttctatca ccttctgcca actagtatga aaggcggcta tttgggcgtt ccgatttttt
    38821 tcgtcgtatc tggttatttg atcacggatc tgctgcggca ggaatgggaa caaaatggaa
    38881 aaatcaatat ttggcaattt tatgtcagaa gaatgaagag actctatccg gcacttgttt
    38941 ttatgcttgt gacagcttcg gcttatatca ctttgtttca gcgagggctg ttaaacaatc
    39001 ttcgaggagt tgtggtcagc agcttactgt atgtcaacaa ctggtggcaa atcaataacg
    39061 gtttatctta tttcgatcga tttgctaatg agtcaccgtt tacgcatatc tggtctttag
    39121 cagtagaagg tcaaaactat ttggtttggc cgatcttgtt tgtattgttg atggtatttg
    39181 ttcgtaaaag aaaatggatc ttttatactg tgttaggtac atccttcctc tccgccatct
    39241 tgatgatgat cttgtataca ccaggaggcg atccaacccg tgtttattac ggtaccgaca
    39301 ctcgtctgtt ttctatatgg ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt
    39361 taaagaaaaa catcccgaaa caagcgaaaa atattctgaa tatcgctgga ggaatctcgc
    39421 ttttggcact gattctttgc ttcttctttt tagatgatca ttacaatttc atctattacg
    39481 gaggaatgct cctagtgagt ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg
    39541 gagcaagttt gaatcgatgg ctgacaaatc cagtatttac ttggattggc aaacgaagct
    39601 atggcattta tctgtatcag tttccagtta tgatttttta tgaagcaaag gtgactgata
    39661 ttgccgatca tgttttgttg catactttag tggaaatcac attgattcta atcatcagtg
    39721 aactttctta tcgatatgtg gagcgtccgc tagcacgttt tgattatggt cgtacattcc
    39781 aagtgatgaa aggatggttc agcaaaccga tcatcagtaa gagcaaacca tgggttgttc
    39841 caggcacatt acttgtagca attgcactcg ttggtttcgt tacggcaccg aaaaacgctg
    39901 taacagccga tcaaaaacaa ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag
    39961 aaaccagaaa caattcagaa aacaccacta gttcggttga ccaagcgatc cttgataagt
    40021 acgagttgtc caaggcacaa gggaataagg cacaaaaatt agaactaacg gcatttggtg
    40081 attcagttat gttggatgct gcaacggatc tacaagaact ttatccaaaa gtagtggtag
    40141 atggagatgt cggacgacaa ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac
    40201 aagatttgtt gaaagacact gttctgattg gactaggaac gaatggctca ttctcggaag
    40261 ctcagtttga tagtgtgatg gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc
    40321 gagtaccgac gaagcgctgg caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa
    40381 aatacgacaa tatgacgctg attgattggt acagctacag taatgaccat agtgactggt
    40441 tttatgatga tcaagtccat ccaaatcctg aagggatgac acattacatt cacttagtca
    40501 gcgaagcctt gctaggagga agttcaagta cgaacagcag tgagacaaac gtgacagaat
    40561 gatagctaca aaaaacttca ggcaaaaaca tttgtttttg cctgaagttt ttttatattt
    40621 accgtgtttt taacattcat atagattcag gaagcaaaac ggttgagtgt gtctgtaaat
    40681 aacgttcttt ttgttttcgg gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc
    40741 ttcttgaaga aaatacttct gcatggatca tcttaacagg tcttcttttt tgaagacgag
    40801 tatatttagc accagtacca ttgttatgtt cctctaatcg tctagaaaga tcggttgtat
    40861 atccaccata aaatgtctga tctttacaga ataatacgta aaaataatgt tcatttgcca
    40921 tagagcatct cacgaatctc tgcagtgtat tctccatcca tattgtaagt gatcaatggt
    40981 ggagcgactt tgaatccgtc taatttgcct tctttgattc cttcaactaa caaaatattt
    41041 gcctcttttc caggttttgg gtaaacaaat tggatccttt taggtgcaat tcgatagtct
    41101 tccatgacct gaatgatttc taagaaccga tcaggacgat ggaccatagt aaagcgtcca
    41161 tttgttttta gtagcttact tgaaatatcg atcacttctt ctaacgtcgt atgaatctca
    41221 tgacgggcga ttgccaggtg tttattaggg ttcgttttat ttgttggcag ccctttgaaa
    41281 taaggtggat tacagacgac taagtcacaa gaattatgtc gaacgacaga taagctgtct
    41341 ttcagatcga tggtgtggac agtcatttgt tcatttaaat ggttaagcgc gatactacgt
    41401 cttgccatgt ctgctagacg aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt
    41461 ttacttaaaa aaagtccaac tgcgccattt cctgcacaaa ggtcaacaat cttccctttt
    41521 ttaggtacac gggaaaagtg agcaagcagc acagcatcta aagaaaaaga aaacactttg
    41581 gaactttgga taatcttgat atcttctgcg tataattggt cgattcgttc gtcttcgtga
    41641 agcatggatt ccctccaaaa tgaaaaaaat agtcgtctgt attatactat ttttattaaa
    41701 aagaaccaag gtggcttgtc aaacctctat tttttatgca tactatgacc ataagaaggg
    41761 aaaggaagag actatgtttt atcgatttat gcgcggggta gttcgagtac tattagcctt
    41821 agttaatgga aatgcccgct atgagaataa agaagtttta ccgcaagatg agaattacat
    41881 actagttgct ccccatcgta cttggtggga cccattatat ctggcggtag ctgcagcacc
    41941 caaggaattc agctttatgg caaaagaaga actgttcaaa aatccagttc tgcgatttat
    42001 attaactcga tccaatgctt ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa
    42061 aacacctgta aagattttga aatcgacaaa tttgagtttg atcatgtttc ccagtgggac
    42121 aagacatgct acagaactta aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa
    42181 aatcgtgcca gctgtatatc aaggtccgtt gacacttggg gatctgttca agcgtcagag
    42241 agtgacagtg cgtttcggcg aaccaatcga cttatcagat atcaagaaaa cggataaaga
    42301 aggtatggcg gagatcgaac gacgaacaca agcagctttt gacaaattgg acaaagaagt
    42361 gaaccctgat ttcaaatatg aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg
    42421 gtcttttgaa tctactgtcc tgttcagttc agactttttc aatgaaaacg agggagagac
    42481 gtcaagtctg ccctcttttt gcgttccaat atgtaaaata gaagacaggt gtcatgtaat
    42541 ggatcaaagt gttataataa ttagaaggac attttttgag gtgattgaat gcgtttttta
    42601 catacagccg attggcatat cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag
    42661 cgtcatgtac tatcttctat actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg
    42721 attgccggag acttatatga taggagtgtc ccagctgttg atgccgtaga attatacaat
    42781 gaattgatgg tcgattggaa tttaaaggaa aagatcccga tttttgctat atcaggaaat
    42841 cacgatagca gtacgagact ttcagcgggt acgccatggt tcagttattc gaactatttt
    42901 ttgcgaacac agctagcaga agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc
    42961 tttcttcctt actttgaacc aattgcagcg agattatatt ttgaagatga caatatccga
    43021 acgatcaagc aagcggtagc caaggtgata gataaaatgc aggagctatt tgattcagaa
    43081 aaaaaacaag tattgattag ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa
    43141 acgaaaatcg aagtaggcgg gttggattcg atccctggtg aactacttac accgtttgat
    43201 tatgtagcac taggacattt gcataatcaa gctgctttga gacaggataa tgctcgctat
    43261 agcggttccc cattgaaatt ctctttatct gagatcaacc aaaaaaaagg cgtatggatc
    43321 gttgacctga caacaggcct ggagttgaat tttagggaga tcgaacccct gcatgatatt
    43381 gaagaaataa cagcgagttt caaagaattg ctggatcctg ccttttatca gtccgtcaat
    43441 cgggagaatt acatctatat ctatctcact gatagaacga tcatcccgaa tatgatgaac
    43501 cagcttcggc aaatatatcc tcgtattttg gggattgaac gggcaaacgg tcgagcagaa
    43561 caaacaaagc gcaaacgaaa agtactagaa atgaaagatc ctcaaaaatt agcagaagca
    43621 ttttttagtg aaatgacgga agagcagcta actgcaaacc aagaaaaatg gctcggagaa
    43681 acgttgcaag aaatcatgga aatggaatga tcaagaatga aaccgaaaaa attacaactt
    43741 aaaaattttg gtccttttat caatgagacc gtagattttt cacgtttgac agaagcaccg
    43801 ctttttttga tcagcgggaa gacaggagct ggcaaaacga cgatttttga tgggatcacc
    43861 ttcgcacttt ttggtgaaac ttccggaaga cttcgctctg gaaaagagat gcgttctttg
    43921 tttgctacac cagacgaaga aacaagcgtg actttttctt ttgaacatca gcagatgagc
    43981 tatgaaatcg aacgaaaacc agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa
    44041 aaacaggcag ccaaagtaac gttgaccatt tttgatggga aaggaaaaga aataaaacaa
    44101 atcacaaaac gtacagaagc agatcagttg atcagagaac tgatgaatct cgatgcgaaa
    44161 cagttttctc aaatcgtttt actaccccaa ggagaattcc gtaatttttt ggtttcatca
    44221 agcagtgata aagagactgt tttacgtcat ttattcggta ctcaattttt ccaacagttc
    44281 aatgagcgat taaaagaaaa agcaaaacaa cagcaacaaa aattggatca tttagagcaa
    44341 gagctgcatc ttctgcaaaa aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg
    44401 tttgaagccg ttttagccca atggacaaac catcaggcaa tactcgaaaa acaaatcacg
    44461 gaagaaaaag aagctctaac ggaacttcag gaaaaacaaa agcaactaga aaattcctac
    44521 tatcgttttg aaagcttgaa aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa
    44581 aaggaattag ctgctcaaaa agacgaaata gaggaaaaga aacgatggat tgggtattat
    44641 gaatttacgc aacgattagt cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa
    44701 atagaactgt cacaaaaaag tagtgagcaa acaaagaaac tagcgatgac tacgcagaat
    44761 tatgaagagt ggcaaaaaaa tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa
    44821 gctgctcaaa aactgcaaaa caaacagatg atggtgccaa ttgtcgaatc cttacgtagt
    44881 aaaaaacaag acgcagaaca attaacaatt tcattggata aagaagaatt gaatgccgag
    44941 aagctgtatc aaaatctcgc tatctatcag gaaagaactc gaattcttca agaaaattta
    45001 ctggatcagg aaaaactgca agaagatcgt cttgcttttg gacagttaaa atatctagat
    45061 gaaaagcagc aagaaataga aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata
    45121 agagaagaac tcaaaaaagc aactgaagaa ataacaaaaa atagtcagct attgaaagaa
    45181 cagacagaac aagcagaaca gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt
    45241 cagctttttt tgcgtccagg ggagccatgt cttgtttgtg gatcaacgga acaccccata
    45301 caacaattaa aacacgaaca gccaaataag gaagatatct taaaagtaga acaacaactg
    45361 gcagaagctg agtctgctgt agaaagaact cagcaaatca ttgccaaaag tgaagcacat
    45421 gaaaataatc ttcaacaaca attatcagat ttagaacaaa aaatcatggc aacgaatata
    45481 caattggctg aacaagaaga acacttgcaa caggctttga aaaaggcatt tcctgagata
    45541 acagaacaaa aaacaaaaac aactcttgta gtaatcgaac aatctttaga tagacgaaaa
    45601 agcaagatgg ccaatgcaag aatagagctg gaagaaataa gacaacaagc agaaaagctc
    45661 gaacaacaat tagctgtcta caaacagcag cagacagaaa aaaataatca gctccagcaa
    45721 ctgcaaggag aaatcaaaag tttagaacaa caattgcaag atacggatag taactgttta
    45781 gaagaggaga tacgacgact tgaaaaacag ttagaagaag actcgaatca actagctgtt
    45841 gagcagaaag caggagtgca attgttgcaa gatcttcata cgcttcggac acagcttgat
    45901 cttcaacatg aacaaataga aaaaatagat gaaaaaatag aaaaggaaca agaaagaata
    45961 gctaaaaagt tagaaagcca gtcgtatttt tcaacaattg aagaaatctg tgcatttgca
    46021 caacagcaag cacaatataa agaaaaccaa cgtacagtta cttcttatca tgaagagcaa
    46081 ttagtgacag ctgaccggct gcgtcaatta gaaaatatcc agctaactga gacattccca
    46141 gatacagaag agatcagcca acagttagaa gaaataagac gtatgatcga aataaagcaa
    46201 gaaaagatat acggtttaca agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt
    46261 ctttcgattt atcacacaag ccagacgaaa ttagatgagc ttacgcaatt acagcagctt
    46321 tcgcaaacat tcaacggaga aaatcctaag aagactagtt tggaacggta tgtgcttcag
    46381 gtttatcttc aagaagtgtt acaagtagca aatgatcatc tccaacgttt aacgaaaaat
    46441 cgttatcaat ttgagctagc ggataccatt ggcagttatc gagggaaaac cggattagaa
    46501 atcaatatct atgatgatca ggcaggtatg tctcgaagtg cgcataccct gtctggcggt
    46561 gagagtttta ttgcagcact ttctttagca ttagctcttg ccgatgtgat ccagacacaa
    46621 gctggtggtg tagcaatcga tgcattgttt attgatgaag gatttgggtc attagatgaa
    46681 gaagctttgg aaatggcaat ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc
    46741 ggcatcatta gtcatgtaag agaattgaaa gaacgagtat tacaacaaat aagaattgat
    46801 acagaaggta gcggacaaag caaaatacgc tatcaacttg gataaaaagg gagattggta
    46861 actatgaaat ggagtattcc agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa
    46921 ggccgagtgt tatcggttgt ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg
    46981 ggcagtgaat tgtatatggt tgatttggat ggtacagcaa aagagataga ttactgccaa
    47041 tgtccctatt gggaggaaca taaatattgt aagcatacag ttgctgtgga actttattta
    47101 cggtcgaaaa atctatctcg tatcatgaaa aaagaccagc caatgctaga accggtaaaa
    47161 gcaacaagtg agggagaaat cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat
    47221 cctcaagcgg tgcaaccttt gattattgaa taccaagtag aaacgattga gactaatcag
    47281 tatcacccag agctttctat tttggcactt tacttgcgta tcggttcatt ggcatcaccg
    47341 aaaaaaacat atatcgtaaa aaacatctat gattttttac aagcttacac agaaaaagaa
    47401 acttacactg ttaataaaca gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa
    47461 gatcaaaaaa tactcacgca tcttgcagga agtgctcaga cgcatcaatt attaggtacg
    47521 aacggcttac aagtcaaagg aaaactagat aaaagatatc tgcttctccc agtagaacaa
    47581 gcccgcttcc tgttagagca gatgaatcag actacacgtt tgcatctgca gataaatgaa
    47641 caaaacgatc aaggaataca attttccgat caaaacaaac ctttatcatt caaagtggaa
    47701 aaatttggag aagattattt gctgcaagca ttgaatgatt ttgatttttt ctttatgcat
    47761 tatcagtggg gagttatcca agggacattt tattctctga cgaaatatca acaaacggtt
    47821 tatcaaactt ggaaacaatt gattcgccga ttggagaaac cagaagtagt gttcaagaaa
    47881 aaagaattac cgtctttgtt taaagagatt atccctctgc tgtcagagat cggcgacgta
    47941 gctattgccc ctgcagtaga agaggaagta gcagatatcc ccgtcgaatt tattttcttt
    48001 ttccgaaaag caaaaggaaa aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc
    48061 tattcgactg acccgaagca tgaggtctcg acagaacagg cttttcaggt gttacgtgac
    48121 acagtagaag agaaacgagt acttgatcta ttcagaatgt atcgctacca gaaaaatgaa
    48181 actggttatg aacgtccatt gccaagcggg gaagaactat atgccttttt ccgcacagaa
    48241 ctatctgtct tccgtcagtt tggtgaagtc agacttggaa gaaaattgcg agagttgtat
    48301 ttagatgcgc ataaacatca accgaaaatc gaagtaaccg agaccggttc atggctcgat
    48361 attcgattcg atgtgacagg gatagaggag caagaaatcg atcatgtcct gcaaagcttg
    48421 ctgagaaatg atgcttttta tacattagaa aatggtcagg ttctttcttt tgattcagaa
    48481 gaatttcaac aaacaagcca agtgttgcaa caattacggg aatcgatacg tacagaagaa
    48541 ggaacgatcc atgtacctaa aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc
    48601 aatgctactt ttagtgaatc gttccaaacg atggtacaag atctcattca tccagaaaga
    48661 taccaggcac agcttcccaa aggattgaat gcaacgatga gagattatca aaagcaaggt
    48721 tttcgatggt tgaagatgtt aggtcattat cagtttggcg gtattttagc cgatgaaatg
    48781 ggacttggga aaacactaca gacaattgcc tttttacttt cggaaaaaga agaacggaaa
    48841 agcttctctg ctttgatcgt agcgcctgcg agcttaattt acaactggca ggcagaggtg
    48901 agaaaattcg ccccttcttt aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa
    48961 gaattactgg ctaaagacac agatatccga gtgacttctt atgccagctt aagacaggat
    49021 ctagctaatt atcagtcgca aaaaattgat tatttgattc ttgatgaggc acaaatggtc
    49081 aaaaatagca gtacgaaaac tgcacaagca ttgagagaat tagctgtacc tcagcggttt
    49141 gcactgagtg ggacaccaat cgagaataat ttagaagaat tgtggtcatt gtttgcaacg
    49201 attatgccag gatttttccc gactaaaaca aaattcaggg aacttgccgc agaagaaatt
    49261 gcgcaaatga ttcgaccgtt tattttacgg cgagataaac aaactgtgtt gaaagacttg
    49321 ccggaaaaaa cagagatgaa tctatattct gcacttacag aagaacaaaa aactgtttat
    49381 ttagcttact tgcgtcaaat gcgtgaagaa atcacatcaa tggattctga agcattcaag
    49441 aaaaaccgga tcgggatact tgctggtctg acaagactgc gacaaatttg ctgcgatcct
    49501 cgtctgttta ttgaagatta ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta
    49561 ctggtagctg ccaaagagaa caaacgaaga gttttgctgt tttctcaatt tacagggatg
    49621 ctgactatct tgcaagaaga gttagccgag ctagggatct cgacatttta tttaagaggc
    49681 agtacgaaac cacaagatcg gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat
    49741 gtttttctga tttccttaaa ggctggggga actggattga atctcacggg agcagatacg
    49801 gtcatcttgt atgacctttg gtggaatcct gccattgaag aacaagctgc tggacgtgca
    49861 catcggatcg gacaaaaaaa tgtggtagaa gtgtggcgta tgatctctga aggaacgatt
    49921 gaggaacgca tggattcact ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa
    49981 ggtaatgaag aacagttgac gaaactgact gaagaagaca tccgcatgat tttaagtgta
    50041 ggagaaatcg aggagtaaga gactcgaaaa agcgttcagt aatgggtaag aaagcctttc
    50101 taaagaagcg attgtttatt tgatttaaaa aatagcaagg aggctgggat tccattttat
    50161 cccagcttcc ttgctatcat ttttttattt ctatttttaa aggttataca aagattgtct
    50221 tcattgtctc taacagctga tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt
    50281 caattttgcg ttctcgatgg ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta
    50341 gaacatcatt gtcgtaatta tcgccaacgt ataaggtctc ttctggaagc atatgaaatt
    50401 ctttctcagc cagctgaaaa atctcttttt ctggtttttg gaaacctgtt gcttgagaaa
    50461 tgagcatatt gcgggaagga atccaattgt tcaattgaag ttgcttcagt ttttttgtct
    50521 gatggtcagt cggcccattt gtgataattc ctaatgggac attcttttcc ttcaagaaat
    50581 cgagggtttt tttgacctcc tcatgcaagc agatattatc aagttcttcc tcgtaaattt
    50641 tttgaaataa gaggccatct tcttccgtaa tatgagggta gtctaaatct tttagtgatt
    50701 ggctgatccg atgtgctcgc atatattcta gtgtccaatc tcctgccatt acttttggga
    50761 agttttcatc actatgatgg cggaaccgga tatatagtgg atgcatatct gcatctgaaa
    50821 caagcggaac gactcttttg accgcgtttc gaaatggctg ctgctgatca tacatcgtat
    50881 catcaacatc aaacacaact gatttaatca aaattttaca cgcctttcgg ttttcattga
    50941 ttttttcaca aatccttgac tattgtaaca gaaaaaattg tctaaaaaag ctgataaata
    51001 aaggtttttc ttactatatt tctatttcct tgacagaata aggtttttat atttcagttt
    51061 ttttcactaa aaatcgtgaa acacgtcaat aagtttgatg aacaaattaa tcattatggt
    51121 agaagtcgat tgatttattt taatgcaatc tctgtggaat tttcgaaaga tttatttttt
    51181 taatacagtc tcaatataac tattcaaaca taaaataacg ttatttgatt tatttgttta
    51241 tagtaaattt tatttagtaa tcattgcttt aaaatactac gcttatataa cagagaaaat
    51301 aagcgttata ataa
//
LOCUS       DAXLPQ010000013        50327 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.013, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000013 DAXLPQ010000000
VERSION     DAXLPQ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.013"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(87..266)
                     /gene="rpmF"
                     /locus_tag="ACF3UO_000988"
     CDS             complement(87..266)
                     /gene="rpmF"
                     /locus_tag="ACF3UO_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFD3657032.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(324..893)
                     /locus_tag="ACF3UO_000989"
     CDS             complement(324..893)
                     /locus_tag="ACF3UO_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFD3657033.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1079..1981
                     /locus_tag="ACF3UO_000990"
     CDS             1079..1981
                     /locus_tag="ACF3UO_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3657034.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="ACF3UO_000991"
     CDS             complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="ACF3UO_000991"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFD3657035.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="ACF3UO_000992"
     CDS             complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="ACF3UO_000992"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFD3657036.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="ACF3UO_000993"
     CDS             complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="ACF3UO_000993"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFD3657037.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8549..8734
                     /locus_tag="ACF3UO_000994"
     CDS             8549..8734
                     /locus_tag="ACF3UO_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFD3657038.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8796..9992)
                     /locus_tag="ACF3UO_000995"
     CDS             complement(8796..9992)
                     /locus_tag="ACF3UO_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFD3657039.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10127..11587)
                     /locus_tag="ACF3UO_000996"
     CDS             complement(10127..11587)
                     /locus_tag="ACF3UO_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFD3657040.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILTKEKGLEQYLF"
     gene            11880..12689
                     /locus_tag="ACF3UO_000997"
     CDS             11880..12689
                     /locus_tag="ACF3UO_000997"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3657041.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12875..15028)
                     /locus_tag="ACF3UO_000998"
     CDS             complement(12875..15028)
                     /locus_tag="ACF3UO_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFD3657042.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15322..16170)
                     /locus_tag="ACF3UO_000999"
     CDS             complement(15322..16170)
                     /locus_tag="ACF3UO_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3657043.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16394..18334)
                     /gene="thrS"
                     /locus_tag="ACF3UO_001000"
     CDS             complement(16394..18334)
                     /gene="thrS"
                     /locus_tag="ACF3UO_001000"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFD3657044.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18671..18850)
                     /locus_tag="ACF3UO_001001"
     CDS             complement(18671..18850)
                     /locus_tag="ACF3UO_001001"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFD3657045.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(18897..20720)
                     /locus_tag="ACF3UO_001002"
     CDS             complement(18897..20720)
                     /locus_tag="ACF3UO_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3657046.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            20998..23277
                     /gene="helD"
                     /locus_tag="ACF3UO_001003"
     CDS             20998..23277
                     /gene="helD"
                     /locus_tag="ACF3UO_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFD3657047.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23370..24017)
                     /locus_tag="ACF3UO_001004"
     CDS             complement(23370..24017)
                     /locus_tag="ACF3UO_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657048.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24196..24915)
                     /locus_tag="ACF3UO_001005"
     CDS             complement(24196..24915)
                     /locus_tag="ACF3UO_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657049.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25046..26197)
                     /locus_tag="ACF3UO_001006"
     CDS             complement(25046..26197)
                     /locus_tag="ACF3UO_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFD3657050.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26414..27154)
                     /locus_tag="ACF3UO_001007"
     CDS             complement(26414..27154)
                     /locus_tag="ACF3UO_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3657051.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27158..27481)
                     /gene="rsfS"
                     /locus_tag="ACF3UO_001008"
     CDS             complement(27158..27481)
                     /gene="rsfS"
                     /locus_tag="ACF3UO_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFD3657052.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27538..28131)
                     /gene="yqeK"
                     /locus_tag="ACF3UO_001009"
     CDS             complement(27538..28131)
                     /gene="yqeK"
                     /locus_tag="ACF3UO_001009"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFD3657053.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28115..28765)
                     /locus_tag="ACF3UO_001010"
     CDS             complement(28115..28765)
                     /locus_tag="ACF3UO_001010"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFD3657054.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28775..29086)
                     /gene="yhbY"
                     /locus_tag="ACF3UO_001011"
     CDS             complement(28775..29086)
                     /gene="yhbY"
                     /locus_tag="ACF3UO_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFD3657055.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29102..30211)
                     /gene="yqeH"
                     /locus_tag="ACF3UO_001012"
     CDS             complement(29102..30211)
                     /gene="yqeH"
                     /locus_tag="ACF3UO_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFD3657056.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30208..30735)
                     /locus_tag="ACF3UO_001013"
     CDS             complement(30208..30735)
                     /locus_tag="ACF3UO_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFD3657057.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(30915..31700)
                     /locus_tag="ACF3UO_001014"
     CDS             complement(30915..31700)
                     /locus_tag="ACF3UO_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFD3657058.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31693..32562)
                     /gene="accD"
                     /locus_tag="ACF3UO_001015"
     CDS             complement(31693..32562)
                     /gene="accD"
                     /locus_tag="ACF3UO_001015"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFD3657059.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32563..33942)
                     /locus_tag="ACF3UO_001016"
     CDS             complement(32563..33942)
                     /locus_tag="ACF3UO_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFD3657060.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(33950..34369)
                     /gene="fabZ"
                     /locus_tag="ACF3UO_001017"
     CDS             complement(33950..34369)
                     /gene="fabZ"
                     /locus_tag="ACF3UO_001017"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFD3657061.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34394..34870)
                     /gene="accB"
                     /locus_tag="ACF3UO_001018"
     CDS             complement(34394..34870)
                     /gene="accB"
                     /locus_tag="ACF3UO_001018"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFD3657062.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34873..36108)
                     /gene="fabF"
                     /locus_tag="ACF3UO_001019"
     CDS             complement(34873..36108)
                     /gene="fabF"
                     /locus_tag="ACF3UO_001019"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFD3657063.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36127..36864)
                     /gene="fabG"
                     /locus_tag="ACF3UO_001020"
     CDS             complement(36127..36864)
                     /gene="fabG"
                     /locus_tag="ACF3UO_001020"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFD3657064.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36876..37793)
                     /gene="fabD"
                     /locus_tag="ACF3UO_001021"
     CDS             complement(36876..37793)
                     /gene="fabD"
                     /locus_tag="ACF3UO_001021"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFD3657065.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(37900..38124)
                     /locus_tag="ACF3UO_001022"
     CDS             complement(37900..38124)
                     /locus_tag="ACF3UO_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFD3657066.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38177..39139)
                     /locus_tag="ACF3UO_001023"
     CDS             complement(38177..39139)
                     /locus_tag="ACF3UO_001023"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFD3657067.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39149..39589)
                     /locus_tag="ACF3UO_001024"
     CDS             complement(39149..39589)
                     /locus_tag="ACF3UO_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3657068.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            39895..40860
                     /locus_tag="ACF3UO_001025"
     CDS             39895..40860
                     /locus_tag="ACF3UO_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFD3657069.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(40917..41147)
                     /locus_tag="ACF3UO_001026"
     CDS             complement(40917..41147)
                     /locus_tag="ACF3UO_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFD3657070.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41233..42120)
                     /locus_tag="ACF3UO_001027"
     CDS             complement(41233..42120)
                     /locus_tag="ACF3UO_001027"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3657071.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42209..43432)
                     /locus_tag="ACF3UO_001028"
     CDS             complement(42209..43432)
                     /locus_tag="ACF3UO_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3657072.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43449..44495)
                     /locus_tag="ACF3UO_001029"
     CDS             complement(43449..44495)
                     /locus_tag="ACF3UO_001029"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3657073.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(44659..46386)
                     /gene="ptsP"
                     /locus_tag="ACF3UO_001030"
     CDS             complement(44659..46386)
                     /gene="ptsP"
                     /locus_tag="ACF3UO_001030"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFD3657074.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(46386..46652)
                     /locus_tag="ACF3UO_001031"
     CDS             complement(46386..46652)
                     /locus_tag="ACF3UO_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFD3657075.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            47131..49365
                     /locus_tag="ACF3UO_001032"
     CDS             47131..49365
                     /locus_tag="ACF3UO_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3657076.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            49513..49833
                     /locus_tag="ACF3UO_001033"
     CDS             49513..49833
                     /locus_tag="ACF3UO_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFD3657077.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(50038..50262)
                     /locus_tag="ACF3UO_001034"
     CDS             complement(50038..50262)
                     /locus_tag="ACF3UO_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFD3657078.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT        14350 a        10801 c         8779 g        16397 t
ORIGIN      
        1 atatttttta tttaccgact acaaaaaaat aaacctcaag gctccatggt tagccttgag
       61 gttttacatt ttctaattaa aatgtattaa gcttcttttg acattacgtc cttaccatca
      121 tagtaaccac aatttgcaca tacgtgatgg ctttttttca tttcaccaca gtttggacat
      181 tcgtttaacc ctttgattgt caatttgtag tgtgtacgac gttttgcttt tttagctttt
      241 gatgttcttc tagctggtac tgccattttg ctacacctcc ttgtaaagtc ttgtatctaa
      301 attagacaca atatattcca atcttacttg ttatcgtcgt cttttgattt agaatcaaaa
      361 agttcagata gttttgcaag acgaggatca attttattct cggcttcttc catttttctg
      421 cgctggtatt cttcttcgga aacaacttcc caatcattgc cttttggaag ttctgttgct
      481 gcttcctctt cttttgtcaa tacccgcatt ggaatcgcca ataagatgtt gtcttcaatc
      541 gactctgcta aattcaataa tggaccttca attagcaaaa tctcatctgc agacatttgt
      601 tcatctctac tttggaattg ttcttctgtc atgaatactt cgtctacaga aaaatccatg
      661 ggcagttcaa caggttctag tgaacgtgtt gaaggaactg tcaaagtcgt ctgcacagtg
      721 taatgaacga tatagccttt cttatcaact gagaccaaac cttcgacttc cactggcgca
      781 acatcaagta ttaaattgtc tcgcttcatg agagcggctt tcaagtcgag cgtctcatga
      841 aaagttaacg gtgtctcctg gtattttctc aattccaata aagaccattt catttttcat
      901 cactcctaag caacaaaagc aattatacag ggcaaaaagc atgttgtcaa tgaaattttc
      961 ttgacacctt gcagttcata aaaaaacaga aaaatcttta ttagaaagcc tctgtttgct
     1021 atcatcctca gaatcattta caataatcat tattccatta aaggagcgga tgatcttcat
     1081 gaacacgaaa gatatcgaat actatgtcca aatcgtcaaa caaaaaaatt ttacgaaagt
     1141 ggctaattat ttccgtgtga gccaacctac tattacatat gcattacaac gtcttgaaaa
     1201 agagtttgac accgtactta ttacaagaga tcgatcgcat cacgaattaa tcgtcacgcc
     1261 ttctggaaag cagctgtttc tccatgcaca aaccattctc caagagattt ctactgcaag
     1321 agctgaaatc actcagttgc aaaagaaaaa gcttcgtttt ggcatgcctc ctattatcgg
     1381 caatgaatac tttcctaaac tgtcaagtta ctttatcaag catgaattga tgaatcaaat
     1441 tgagattacc gatggaggct ctcgggactt atacgggatg atccgacaag ggaggatcga
     1501 tttagctgta ttaggctcaa cacagccaat cgtggatcaa tatttagaaa cagagttact
     1561 tttggacaaa cgtttcatga tcgtcgtgcc acctacacat cctctttcca agcaggatac
     1621 tgtctctttc aaagatatag cagatgaaca gtttgtacta ttgaacgaac attatgtcca
     1681 ccccgcagca ttcactaagc tttctaaaca aacacatact catccaaaag ttgtttatca
     1741 aagcaatgac ttgacgattt taaagagtat ggtccgagaa aatgtgggta tcggtttttt
     1801 ggcagagatt gctgtccatc ctgaagatca tttagtttgc ctccctcttt cagatgaagt
     1861 tcagcctcgc ttcttgattt cattggcaaa acgaacacag cagatcgtca cgcctcttca
     1921 agaacaagta gtccaagtta tccatgaatt cgttacagca caaaaaaaca gctcttcgta
     1981 aaagaagagc tgtttttatt ttttattaag ctaaattaga tagctgttgt ttcgccacgg
     2041 taaacgatgc cgcgacgtga atcaacggta atcaattcac cttctgtaat tgttgttgtt
     2101 gcgcctttag caccaacgat tacaggaata tcttgtgcaa ttcctacaac tgcagcgtga
     2161 gaagtcaatc cgccttcttc aacgataaca gcagctgctt tttcgattgc aggcatatat
     2221 tctttgtcag ttgatggtac aactagaacc attccgtctt ttgctttttt tacagcttct
     2281 tcagcagatg aagcaataac tgcatttgca acgacagatt tttgtccaac gccttgagct
     2341 tctaataatt tagaaccaat catttgaatt ttcatcacgt tagttgttcc gcgttcacca
     2401 actggtacac cagcagtgat caagattaaa tcgccttctg atgcgaaacc taattcaaca
     2461 gcttttttag ctgctagttc aaacatttca tcagttgttg atggtttttc agcaactgtt
     2521 gggtaaacgc cccagtttaa catcaaacca cgttttgtgc gttcgtcaaa agtaacagcc
     2581 aagatatctg catctggacg atattttgaa atcatttttg cagtgtatcc tgattcagtt
     2641 gcagcaacga ttgttttcac gcctagattt tttgcagcac gagctacaga taaaccgatt
     2701 gtttcagtta catctgtttt atcgaattcg ttcaattgga atgtacctaa ttctgataat
     2761 gcattttcag cttcttggtc gatacgtgcc attgttgaaa cagcttcaac tgggtagtcc
     2821 ccgtttgcag attcaccaga tagcattgtt gcatctgtgc catcaaatac agcgttagca
     2881 acgtcagaag cttccgcacg tgttggacgt gggttttctt gcattgattc taacatttgt
     2941 gtagcagtga taactgggat accagcagca ttacattttt tgataatgcg tttttgaacc
     3001 attggtacta gttcagctgg gatttcaaca cccatatctc cgcgggcaat cataacaccg
     3061 tcagaaactt tgatgatttc gtcaatgttg tcgatacctt cttgagattc gattttaggg
     3121 aagatttgaa catgagtcat gtctttttct tctaagattt cgcggatatc tagaacgtct
     3181 tgtgctttac gtacaaaact tgcagcgata aagtcgatat cgttgtctaa accaaaacga
     3241 atatcgtcag catcttttgg agtaatacct ggcaaactaa tagaaacgcc tggtgcattt
     3301 acccctttac gtgatcctag catacctgca tttttaactt ctacgactaa ttcacggttt
     3361 gcttcgtctt tttcaatgat ttgcatatcg atcaaaccat catcaaataa aatgtgtccg
     3421 ccaacgtgaa catcgtcaaa taatcctggg taagtaaccg cgattttttc ttttgaacct
     3481 acatgttcag gatccataga gatgcgtgtt tgatctccta cttcaaattt gatgtatcct
     3541 gcacgaccaa aatcagcttc tgttgtgcct tgaacagttg tacggatttc agctcctttt
     3601 gtatctaaaa gaataccgac atcttttcct gtctttttaa ctgcttcacg gaccatagtc
     3661 atacgtgata attgttcttc atggtcacca tgagaaaaat taaagcggaa gacatttgcc
     3721 ccagattcaa tcaattgaga aataatttct actgagttac ttgctggtcc taatgtacta
     3781 acgattttgg tttttttcat ttaaaaaact ctcccattca attttgttta tttaaagctg
     3841 tacacagctt aaatagcttg gtttctttca ctcttaaaat gaaagtgaat tatttagatc
     3901 atatagtgat aagtctggtt tatgtttgtt gttttcaagt gtatcaatga tgtcagacgc
     3961 aacgatttcg ttgtcatgga taccgacaca taatccacct tttccttctt gaagcaattc
     4021 gacagcgtaa gcaccgaatt tacttgccaa cacgcggtcg cgtgcgcttg gtgctccacc
     4081 acggacaacg tgtcccaaga tagatacacg tgtatgatag tcaccaaatt ctgaaagttt
     4141 ctcagcgaat tcatttccgc ccattacacc ttcagccaag atgatcaagc aatgtttctt
     4201 cccgcgatcg cggccttctt ggattttttt agcaactgaa gccatatcaa aatcatgttc
     4261 tgggatgatg atttcatccg ctccgccagc cacacctgac cataaagcga tgtctcctgc
     4321 attgcgtccc attacttcga taacgaatgt acgaacatga gaagtcgctg tgtcacgaat
     4381 acggtcaatt gattctagta ctgtattgat tgctgtatca aaaccgattg tgaaatcagt
     4441 cccaggaata tcattatcga ttgttccagg aatacctact gctgggaaac cgcgttttgt
     4501 caaagccatt gcgccatgat aagagccgtc tcctccgata accactagac cttcgattcc
     4561 gaattttttc aattgttcga ttccttttaa ttgaccttct tcagttgcaa attctggata
     4621 acgtgcagaa tacaagaatg taccaccacg ttggatcttg tcacctacat ctgccacatc
     4681 aagacgacga atatctccag caactaaacc ggcaaaacca taattgatcc cgtatacttc
     4741 cagtccttcg taaatacctt tacgaacaac ggcacgaaca gctgcattca ttccaggtgc
     4801 gtctccgcca ctggtcaaaa ttccgatgcg tttcataata aacattcacc tcattaaaat
     4861 actttatcct aagtatgact taggtttaca accatttttg cgttaaccac gactaacatt
     4921 ctaacattat ttttctcact tgtcttgatt tacggataaa aaaatgaaaa aaaatgaaag
     4981 caagtagtat tttttaccgt aagttatttg aaaaccacat tatcttcgcc aagcagataa
     5041 ataagttgcc cctttatact cttgctgtca tccacccaat aagcatctga cagaactact
     5101 tttcgttgcg ttttttcgtg atacataact actggtatat atcctgggtg tttctgaaaa
     5161 atcacttgta attgtttcat tatctcggga tcttcccgtt cttctgtaat acgcaaatag
     5221 caagtttgtg aaggatactg ggcttctaac tggttaggat cagcaaagct ttctccaatt
     5281 agttgcagtt cctgattata tttgctgatt tcgctccgcc cttgaacaaa gatcactcga
     5341 tcaacggcaa acaaattacg atatttacga taaagagttg gaaaaactgt gacagaaatt
     5401 tctccactac tgtcggttcc ttcaacaaag gccatcagtt ctcctttttt tgtccgaatt
     5461 tctctaactt ccttgatcat cactaataaa ttgactggtt gattagggac gatatctgta
     5521 atcagctgaa cttgtttagc taaacgaaga cgatcaaacc cttctgcagg atgacctgac
     5581 aaataaatac ctaagtactc ctcttccagc ttcaagcgtt cttctagtgt atagtcagcg
     5641 acttcttctt cttttaatgc catgattccc agcaagtcaa gacttccacc actgtaaacg
     5701 atattttgga tttttccttc gagatcaagc atcaattgtt tcctgttagg agataattca
     5761 tcaaaaactc ctactgctgt cagtgattgc agtaactcta atttcagcca acgcttatcg
     5821 atccgtatga ggaattgatc cactgactgg aacgggccat tttgttttct ttcgtttaat
     5881 atatcttcta caaaatcacg ccgaatacct tttatcgctg tcagtccgaa tctgatttct
     5941 tccttattga ccaactcaaa actggaatta ctttgattaa tggacggcga ggaaagtttg
     6001 agtttatttt tacgtgcttc tgcaatatat tctttcaatt ttgatgtgtt atgccgaaca
     6061 gaattcatca ggctggtaaa gaaagcacct ggatgatggg cttttagata cgccatttgg
     6121 aatcccacga atgaataagc aaatgcatgt gaccgattga atccatagtt tgcaaatttt
     6181 tcgatatatt catatacggt cgctgctgtt ttttccgaat atccctgttg taatgctcct
     6241 gatacaaaat gcgacttttc ttcatctaat acgtcttttt tctttttact cactgcccgt
     6301 cgcagaatat ctgactgccc taatgtaaat ccagccatag tcgaggcgat ctgcatgatt
     6361 tgttcctgat agacgatcac tccatatgtg tttttcaaaa tcgggatcag tgaatcatct
     6421 gggtagcgaa tggcttcttt tcctttcttc ctggcaatga aggtatctat attttgcata
     6481 gggcctggtc gatacaatgc attgactgcg gcaatatctt cgatgttttc tggatctaat
     6541 cttcgtaaaa cgttccggat accagcagat tcaaattgaa atactcctga ggtttcgcct
     6601 cgttgaaaca agagcagcgt ttttgcatca tttagcggga tctcttttaa tcggatctca
     6661 tacccttcta ctcgcttaac agctttcaaa gtaaaatcaa taatcgataa gttgcgtagt
     6721 cctaaaaagt ccattttcaa aagaccgatt gcttctacct cattcatcgt atactgggtc
     6781 agaaaagctt catcagaacc gcgttggagc ggaactagtt caagtagatt cttatcgctg
     6841 ataactacac ctgctgcgtg agtcgaaaca tgtcttggca atccttctaa aatcactgca
     6901 gttttgaata aaagttggtt tttttcgctt gcctgaacta attctactaa ttgatgcgaa
     6961 gttttataag cttgggtcaa tgtgattttc aattgattgg gtattgcttt tgaccagcgg
     7021 tttgcttcac tttgcgataa accaaacact ctagctgcat ctctaagaac catttttgct
     7081 gccattgtgc caaatgttgc gatttgtgcc atatgatatt gtccatactt ttctcgaaca
     7141 taattcaata cttcttcacg tcgattgtca ggaatatcca aatcgatatc tggcatcgta
     7201 aagcgttcgg ggtttaaaaa gcgttcgaac agcaaatcat attctaatgg atccacatct
     7261 gtgatttcta acacataggc tactaatgaa cccgcagcag aaccacgacc tgcaccggta
     7321 acgattttgt ttctatgagc aaaagccatt acatcccata cgatcaagaa ataatcatcg
     7381 aatcccattt gatggatgac agataactcg tagtccaaac gttcttggta ttcctttgta
     7441 tagtcagtga ttcggcgttc cacttgcgaa tagcataact ctcttaaata ttctccagct
     7501 tgttttccat taggaactgg ataatgcgga agtaatttct gatggaactg gaattcaaat
     7561 gaaatcgatt cagctaaacg ctgggcgcct attacagctt gggaaagacc cgctttttcg
     7621 aatcgtttga tcatttcttg ttctgaaaga agatagacat ttgctgttag tggtaaagat
     7681 gcagataaat tttctaaagg tatttggctt ccctctttga tatgtttcat cacttcaagt
     7741 gcaaaaagtt cttcttgttg taaactagcg atgggatgta atgcacaaag cgaataattt
     7801 tcttttatca catactgata ccattcaggc aattgatcag gcgtgttttc tgtcaagccg
     7861 atataaaaat ttctagtaaa aacattttca agtaaaaact gccaatgacc gaaaaagtta
     7921 tcctctttat tgaaagcctc agaaacagaa tgatttgccg gaacaacaaa cgctagatgg
     7981 tcggtttctg tcatttctgc aagttccaat ttttcttgga tcatttttcg gctggaaagt
     8041 ttcatcagct gctgataacc tatttcatct tttgcgtacg caagcaagcc ataatttttt
     8101 tcttcataag tataactaag atgtaatcca atgattggct gtactccttc ttctacacaa
     8161 atacgataga attcaggtgc accgtataag acatctttat ccgttatggc taatgaagtg
     8221 tagccttgtt tttttgcttc ttgtacatat tctcgaatac gtatcgtact ttgtaaaaga
     8281 gaataagaag taattgtata aagttgtggg aaaaacatct tgcattccgc cttttttttc
     8341 gttaaaattc actagcgtta aaaggtttga tccttttact ttcattaaga tagcaggcgc
     8401 tgaagttgat tattccactt catttgcttg cttgtaatct gtaggaatga gttctttcgc
     8461 aagaactcaa attttattga gatttggtct cgtttcttta cattcaaaga aaatctggta
     8521 aaattaagat agaaaagagg tgttctttat gcgatatatc gttacattat tctgggctgt
     8581 cgttctaggt caagtagtcg gttatattgg tgctgcatta acaagcggaa catatgattt
     8641 tactttgaca acaatcattt cattcattgc gggtgtcatt atccttttga ttggtgcagt
     8701 tgcgccaaga aaagaaacct ctgcccattc gtaaaaaaac agccaagagc ttgagatttc
     8761 tcaagctctt ttttattttc tactcctcac caccattata atctgctgcg aagaacttta
     8821 cgaaagttga ataaagaaag aagaatattt gacagaacaa acaaacttgt cacaataaaa
     8881 acagcactgt aattataagc atgcgcgact gtcgatccta gcatgggacc taaaacttgt
     8941 ccaaagttgc taaacatctg attgtagcta tagattcggc tgactccttc ttgaggcgta
     9001 atcttactga tcagtgtatt gacagaaggc atcaaagcgc cagttgaaaa gcctaaaata
     9061 aagcgaagta tacctaattg gagcggtgta gtgacgaatg ccataggtaa ataacagcaa
     9121 aatgataaaa tgagtcctcc aattagaact ttttgattcc caatcttatc ccctagtttt
     9181 cctagtttcg gtgaagaaaa gacagcggaa acaccagcta tcgaaacaat caagccgctg
     9241 acaaaaagga tattttctgt acttccgctc aattcacgaa tatataaggt caaaataggg
     9301 ctgatcgtag tgattcctat ctgtaaaatc aaggtcgtaa tgaagagacc gatcaaaata
     9361 gagagatgat ccatttttga aaaaatttct ttggtgctta tcagatcttt tttctcgatt
     9421 ggatggaaat cttctttgac taagaaaatg gtcaataccg ttgtgatcat caacaaagcc
     9481 cctgtgatca agaatacatt ttccatacca aaccactgag ccagtgcacc gcccattgaa
     9541 ggtccgatca gatttccagc aatcgctccg gtagacaatg ttcctaacgc ccatccgctc
     9601 ttttctctag gtgcctgtga agcaatcatc gctgtggcat ttggaatata tccagacaaa
     9661 atcccattcc aaaaccgcat gatcaaaagc caatacgcgt ttggtacaaa agccaaagat
     9721 cccattgtta atgtcatccc tgctgctgca cggatcatca tgagttttcg gccttttcga
     9781 tcagctagat ttccccagat tggtgcaacc acggcagatg caaaagcagt cacagagatt
     9841 gctagtcccg aaaacaattc gatttgatct tttggtgttc ctagttgctc aacataaact
     9901 ggtatgaatg gcataactaa actaatactt gcaccagtga aaaaacagcc aatccacgca
     9961 atcactaaat tttttctcca attaatctcc atctatcatc cctctttcgt ctcttttatc
    10021 atacctattt tcgaataaac aagcaacgat ctcgccagta aaaagagaaa aatcccgcaa
    10081 aggtcatttt atatgtaacg ttctttttat gtaaaacaaa aagagatcag aacaaatact
    10141 gttccaatcc cttctcttta gttaaaatga tgaagttgat aatgaataaa atatcaacga
    10201 tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca attgtataga
    10261 aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata aagatcgatg
    10321 caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca aaagaagcca
    10381 tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt acaatggcga
    10441 tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact gaagtcaaac
    10501 cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt gtattcgatg
    10561 taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct ttatccattt
    10621 ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag aaaatacctg
    10681 tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat aaactgaatg
    10741 cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa gattgcatgc
    10801 cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa ttacctaacg
    10861 aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata ccaaggactg
    10921 tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact aaaatggctg
    10981 tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg gctaacgcag
    11041 ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg acagagctcg
    11101 aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt ccgacatacg
    11161 caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga atcgcccgaa
    11221 taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg caaataaaca
    11281 ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta aaagtgaaaa
    11341 atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac aatcccatta
    11401 ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg aagggcatac
    11461 ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca aagaatgtcg
    11521 ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa ccgaaaaact
    11581 tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata ataataaaaa
    11641 ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt ttcattcgct
    11701 tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg tttagcttat
    11761 gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga ttgctcttgt
    11821 taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa ggacccttat
    11881 tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa gattcgatga
    11941 ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat catgtcagta
    12001 ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta gaattaacaa
    12061 caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac tgggatggtg
    12121 aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa aaaaagcagc
    12181 taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac agttttgatt
    12241 tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg ctttctccta
    12301 aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt tttgcaggag
    12361 ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg acatggggtg
    12421 gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa ggcgtgcaag
    12481 agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt gacgagcata
    12541 atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac ggtactgacc
    12601 aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac ggtttagctg
    12661 tttatctgga aaaactactt aaactataat agagaattag attccacaaa aaagaggttg
    12721 tgacaatttt tgtcacaacc ttttttgccg agtaaacggt gttcaaaagc cagtttctcg
    12781 gtatgaagtc aaatttaagc aaaaatgtga gaagctattt tcacaaaatt tttcttcata
    12841 ctcgaaacta agcggctttt tcacgacctc ttttttattt tgccatgaac atatcataat
    12901 acgcgtccat tatttcttta gcaatcgtca agtttatgtg gtcttgttcg tctaataagt
    12961 tcggcaagac aacactgatg gcaatttccg gattgtctgt tggtccgtat gccacgatat
    13021 tactattgac tgtcgcaata tctggatgac cttccgcaac cgtttctgca gtccctgttt
    13081 ttgcggaaag gtccattttc gcactggcta atggtttggc tgttgtgtaa ggatcggtac
    13141 catggacaac ttggtggaat ccttcacgga ggatcgccat attttctgca gaaatattga
    13201 ccgtattttc tactgttgtg ccaatttctt tcttcacttc acccaagttt ccattttcgt
    13261 cattgccata gatcgctttg actaggtgcg gctgtactcg tttcccgcca ttagcgactg
    13321 ttgaagcata ttgagctaat tggattggtg tatatgtgtc aaactgtcca aatgccaaat
    13381 cggtaaagtt acctggagca taccattctt tgccattatc cgcattgaac ttcttcatat
    13441 aatcaacaga acgtgagatc ccaggagatt cattcggcaa atcgatccca gtcgttgtac
    13501 caagaccaaa ctctttgaaa gagtctctca attgctgata agctttagct tcttcatcta
    13561 aactaggtag tcccattcca ggtgtatagt ctagtcctaa catctttaac gccactttga
    13621 tcatatacgt attagaagac aattccgatg ctttgactgc atcaagagca acttgtccgc
    13681 ttcgattaaa gacagagctt ttttctgaag caccttgcag acgaatcggc tcatcaatca
    13741 aaacttgatt tccgctgatc gcgttacttg cccagcctgc tgtcaaagta ccagccttga
    13801 ctacagaccc tggatcaaag gcgctagtaa tcgtgcctaa agcattctcg gtgatttctt
    13861 tggaaccttg ttcatgactg aaaccagtca ttgctagcac ttctcctgtc tgaggattca
    13921 tagccactgc ataagcacca ggcgaatact gtgctttgcc gttgttgatc aatgtttgat
    13981 aattcctttt caaaatttct tctacttttg attggaattc tgcattcata gataacatta
    14041 aattagaacc tttttcccca gagaagattt ctttttgatt cgaaacattt ccttcattat
    14101 caagggaaac ttcatattgg gttttggttc cttgcaggac atcttcatat tgtttttcca
    14161 aataactttg tcctacacgg tcattccgag aataaccttt tgctaggtat ttctctgctt
    14221 catctgctgg aagtccttgc ttttcagtcg tcacactgcc aagaatactt ttcagtgaac
    14281 ttgctgcatt atattctcgt gtccagtctg tgccagtcga aactcctgga agttcagaag
    14341 cgcgttctgc cacaacagct aactcttgat cagtaacacc agagtttttg atatagacag
    14401 tgtttaattc atatgcacta ttcatccgtt taaagatggt agcaattttt aattgctcct
    14461 cgtttaaatt aatctcatca gctgtgactt tattgaccat cgcactatat tgttcgctgt
    14521 tccctaattg cttttctttt gccgaaagtc tttttgtggc ttctttcaaa tgtttgggat
    14581 cagccagcca aaaatctttt ttatctctat ctgtcagatt ttcatctacc ggaacatcga
    14641 tcagcgagtt cagcttcgtt gcgatttcaa gcaaatcttt agccgtaact tgtgttcctc
    14701 tcgtatatgt gatggcctga ttcgctttat tcgtaactaa agcttttcct gtggagtcgt
    14761 agatcattcc gcgaggagta ctttcttgga ccgtaatcgt agaagtagac ttcactcgcg
    14821 cctccatctc ttcgccgttc acgatctgca aataacccaa tctagcaatc aacgcaacaa
    14881 ataacgtaaa tataatgaaa aaaagaaaat ttaagcgaaa aggaacatgg gaccggcgaa
    14941 acgttttgtt cttaggttct tgtgcacctt ttcttatttt ttctaaccaa gaagtattta
    15001 atattttttt cataaaatct ttcatcattt cctatccttc cgcctattta cattcatgct
    15061 tcattgtacc caaaaacttc ttaataaaaa agaaaaaatg ggcggagcaa gaaattcttt
    15121 acctaatttc aagataaaat caactttttg tttcacagca atcacttaaa gttacatatc
    15181 caactatttt tttcattaaa aaataaactt atttttgaaa attatgtttt cttaagtcgt
    15241 gaaacacttt gatggatcat ttatttgtgg aaaactacgt tttgttattc taaaaaactt
    15301 atataaaaaa tagtaaggtt tttatttcga atccataaaa tattcttgga ttgcttctcg
    15361 tgtttttttc actttttcgc taagcttttc gtttttagcc atatagaaat aaaaaatgat
    15421 atcgatcgta gcaaattggg ccaaaagtga attagttgcc gcacttcgat tcgtgatttc
    15481 ttttggtcta gatgtttgta cgagtacatc ggctatcttg ctaagcgggt tatttccaaa
    15541 ttgcgtcaac gcaatgattt cgatattcat gcttttcgcc agctcggcta atgcgactac
    15601 atctgcactt ctacctgagt ttgaaacaag ccaaagcact ttctttttct cattgctgac
    15661 aagttgcggg agcaagacgt ggatatcttt ttcaaaaatg attggcttac cgacacgaga
    15721 ccatttttgc agaatatctt ctactactaa agaagaggcg ccaaccccat ataaaaaaac
    15781 agtctctgcc gattccaaac actctacgac tttttggatc gtttcttctt ctagaatatc
    15841 tactgtttct tttatcgcta cttgtgcatt gttaccaagt ttgtttttga tagagtaaaa
    15901 ggactcattt gcttctatat cactaaaacc ttcatcgatt ccagtctgta gttctgttga
    15961 aatcgtgatt ttgaagtccg tcagactttg aaaaccgatt tttttggaaa aacgtacaac
    16021 tgtcggcgca ctcaacccgg aagcttctgc taattcatta gctgtcattg tagggacctt
    16081 ctcaatatta ccgataatgt agttggccaa ctttttttct gctgaagaat aatcttccat
    16141 catactttca atacgactaa ttacgctcat aagttcctcc acccttttaa tgatagtcta
    16201 tgtaagtata ccatatcaga cccttattca cggtcgtata ctggataaaa aacaaaaaaa
    16261 caatccgccc aacagaatat cttatcccat caatcccaca gattctattg agcatctgtg
    16321 tctttgagga atacctgtta tctattgttc ggattgcttt ctatctacta cttttttaca
    16381 ggaaatttac ctattagttt tctctgctgt aatttttgac ttctgcttcc atagcatcaa
    16441 taaagatatt caaatcttct acagctgttt ctttacttcc ataacgacgt acgttcactg
    16501 ttgcatcttc caattccttg tctccaacaa ctaattggta agggatcttt tgtgtttgag
    16561 aggcacgtat cttatagccc attttttcat tacgatcatc aacttctaca cgcaacccct
    16621 tcatttgcaa acgttctttg atttcataag cataatcgcc atgtgcatca acagaaacag
    16681 ggatgattgt tgcttgtata ggtgccaacc atgttggaaa agcgcctttg tatacttctg
    16741 ttaaataagc gacaaaacgt tccattgtag aaacaattcc gcggtggata actactggac
    16801 gatgcgtatt ttccccgtct tctccaacat atgtcaaatc aaagcgctct ggcaataaga
    16861 agtctaattg tatagttgat aatgtttctt ctgtaccaag agctgttttg acttgaacat
    16921 ctagttttgg tccgtaaaag gctgcctcgc cttctgcttc aaagtaatct agttctaatt
    16981 catccatagc ggctttcagc attgcttggg ctttttccca cattgcgtca tcatcaaaat
    17041 atttatctgt attgtttgga tcgcgatagc tcaagcggaa acgataatct gtaatattga
    17101 agtcagcata tactgccacc atcaattcaa gcgtacgttt aaattcatct ttgatttgat
    17161 caggacgaac aaatgtatga ccatcattca acgtcatttc tcgtacacgt tgtaaacctg
    17221 acaaagcacc tgatttttca tagcgatgca tcattcctaa ttcagcgata cgaattggta
    17281 attcacgata agaatggatc gtgtttttgt agaccatcat gtgatgaggg cagttcattg
    17341 ggcgaagaac aagcatttcg ccatctccca tatccattgg cgggaacatg tcttcttgat
    17401 aatgatccca gtgtccagat gttttgtaca actcaacatc tcccattatt ggtgtatata
    17461 catgttggta acctagacta acttctttgt ctacgatata acgttcgatc gtgcgtcgga
    17521 ttgttgcccc ttttggaagc cagaatggca aaccagaacc tacttctggg gaaaccatga
    17581 acaagtcaag ttcttttcct agtttacgat ggtctctttc ttttgcttct tcacggagac
    17641 ggatatattc tttcaaagct ttcttgtcaa aaaaggctgt cccgtataca cgttgcatca
    17701 tttgattgtt tgagtttcca cgccaataag cacctgccac tgataataat ttaaatactt
    17761 gtatacggcc agtggatgga acatgtggtc cacgacacaa atcgatgaat tcgccttgtt
    17821 gataagcagt aatcacttct tcttctggca attcactaat cagttctact ttgtacggat
    17881 cacttgcaaa aatttctaat gcttcctgtt ttgaaagaac acggcgttcg atcggcagat
    17941 tttctttgac gattttcatc atttctgctt cgattgccgg caaatcttct gcagttactt
    18001 ggttttgtcc attatctgta tcgtagtaaa accctgaatc gatagctggt ccaacgccaa
    18061 agtggatatt tggatagagg cgacgcatgg cttgggccat caaatgagct gctgaatgac
    18121 ggactaagcc aagtgcatct tcatggtctg gtgtgatgat ctcaatactt gcatcttcct
    18181 cgattggacg agtcaaatca acgagttttc cgttcacttt accagctaaa gctttttttg
    18241 ctaagctttt tgaaatgctt tcagcaattg ccaatgttgt tgttccagac tcaaattctt
    18301 tgactgcacc atctggaaaa gtaattttta tcataatagt ttcctccttg aaatgttttg
    18361 attgatcaga tcatcaagct gaaaaacaaa aaaatcctag catctcttga aaagagatac
    18421 taggacgaaa agttcgtggt tccacctaat gttcaaacgc aaatgcgttc ctcaagcgtt
    18481 gtaacggtcc gaccgccctt gcttcaacaa gggtttcgaa agtggtcatc ctttggtttt
    18541 ctcctggaaa agtttcagcc tagcttttcc tctcttatcg aagactctca aattcagttg
    18601 gctttctcat caatcaatta tgtgtttatt taaccactaa taaatagaaa aatcaagtgg
    18661 gaaactaaac ttattttttc cattccccat ttacaccgta tgttcctttt ttcatctcat
    18721 tgatgatgac atggatgtgt tcttttggtg cctgcgtgtt tttatgaaca gcttccgtga
    18781 tatctttcat catattttct aattgttccg gactgcgacc ttctactaat tcgacatgta
    18841 cgaatggcat aatgctctct cctctttctg atcgttcttt tttcaactcg attctatcat
    18901 actatgtttg tcttgggtac tgaatcagga aaaatggctg gatctttttt tgctctcaag
    18961 gcactcaaaa tagagaccgt atccacgact tcttgcaaaa cagctccgaa taatgcgggg
    19021 attagtcccg tacttgcaat taacatcaaa aaaatacaaa taaagatgcc aatcagtaca
    19081 gactgtttcg ctattctcat cgtatctctt gaaatcacta ctgcttttgc tacacgcaag
    19141 agatcatctt tcaagatgac cgcatctgca ctttcactag cagctgtaga accatgagcc
    19201 cccattgcaa taccgatatc tgcagcagca agtgctggtg cgtcattcac gccgtctcct
    19261 accatcgcaa caggtctttg atctttaggg atactttcta aaatggtcag tttatcttga
    19321 ggcaagctac gggcatgtac agaatctaat tggacttttt ctgcaatcgt ttgagcaatg
    19381 gcagatccat ccccggtgat catcatcaaa tttttcacat caagttttct tagctccttg
    19441 attgtctttg ctgcttctgg gcgaatctga tccgaaaata ggatcgttcc tgcaaaagat
    19501 cgatcaattg ttacatagat tgctgtattg gacgtttcta tttcttcagc tgaaacaaaa
    19561 gaggcacgtc caatctttac ttcatgatta ttgactactg cttggattcc ttgaccggtc
    19621 acttctttca gttgactaac aggatacagt tggctgtttt tcacgttgtt cactaacgaa
    19681 cgagctaaga tatggctaga ttcctgttct gcactagctg catacagaag tagctcttct
    19741 ttttttattc cattgactgg ctgaatcgcc tctacttcca atatcccttt ggtaagcgtt
    19801 cctgttttat caaaagcaat cgtttttgta cgtgcgagct tttcaatcgt tgttccagtt
    19861 tttacaacga tcccgttttt acttgaacgg ctcattcctg caactaaagc aatgggcgca
    19921 gctagaatca gtggacaagg tgatgccact accagtacct cagcaaatcg taaagggtct
    19981 tttgagaacc accaagaaat accaccgatc aaataagcaa tcaacgtgaa agggactgca
    20041 taacgatcag ctaaacggac aaatcgggca ggcttttctt ttgattcttc gactagttta
    20101 ataatcattt gatactggct gtctgcggca cgtttttcag cgatcatttg gatcgatccg
    20161 tctccattta aagaccctga cataatctga tctccaggtt tcttggtttc cgggcgggac
    20221 tcacctgtca aagaagattc atcgaccgaa gattctcctt tggtcactcg accatctgcg
    20281 ggtacaagtt cgccaggctt gactagtaac tggtcatcaa tatttatttc atcgattact
    20341 atatcctgca attttccttc tttgaatcga tgggcaattc ttggggtgtt atctaacaaa
    20401 gactgcagtt ctttacccgc tcgtttattc gcgtaatcct ctagactatc tccgcccgta
    20461 agcatgatca atatcatcaa actagcccag tattctttga cggctaatgt tgcaaggatt
    20521 gcggtaatcg ctaatacatc tacgccatat cttcctgaac gtaacgtctt gatcatttcc
    20581 aaaaacatca agaaggcgag aatccctcca gtaaatgcga caatcgcaaa tgcaagggcc
    20641 ggctggtgaa aaacaaattc acttaataaa gctatcccac caataagcaa agtaagtaaa
    20701 aattttttga aatgtgtcat tgttttttct cctcttttat gtgacttaga gaggttagta
    20761 ataaatttcc agctgcctct ttcatcttaa gcatagtcct tgactagcac tttttaaaac
    20821 aataggcctt aattgaaaac aactatcact atcagcgttt ccaaaattca tcagttctac
    20881 aaacaaaaat attcagcaag gattactttt tcgattcatc agttaaaaag tacctttttt
    20941 cgaaaaacta tgctatactt ttaattcgtt atttacggcg gaaggagcaa acatgcgatg
    21001 aatgagaaac aactagaaca aacgcacgtg gatgaaacga tcgaactaat ccagatcgaa
    21061 caaaatatgc tggatacaaa acaacaagaa ttgactcagg aaatgaatca ttcgacaaaa
    21121 gacacagcta atcacaagat tcgagctggt tccaatgaag ctttttatga atctgctgtt
    21181 gaatatcgcc aacatgagca ggaattgctt ttgaaatacc atactcttga agcacagcaa
    21241 aaacgcctgc aaacgttgtc tgtcatgaaa gatagtcctt attttgcccg tatcgacttt
    21301 aaagaagacc gtgaaacaga aacattatat ctaggtatcg cttctttaag agatctggca
    21361 gaagaaacaa tcgttattga ctggcgcgca ccaattgcca atctttatta tgaaggtgag
    21421 attggtcccg cattttatga aactgaaaca gatagaatag atgtcgatct gcagttgaaa
    21481 cgacaattta aaatccaaga aggacgtatt ttatctatgg tagatacgtc ggaagtaatc
    21541 aatgatgact ttttgctaga gatattggat gaatcatcaa gcaaccatat gaaaaacatc
    21601 gtctctacga tacaaaaagc acaaaatgca atcattcggg acacaacaag taaagtaatg
    21661 ctgattgaag gaatcgccgg aagtggaaag acatccgctt tgcttcaacg tattgctttt
    21721 ctgttgtatc ataatcgcaa gtggctcgag gctgaaaacg ttcttctatt ttcacccaac
    21781 catttgtttt ctgattacat ctcgactgta ttgccttcat taggtgaaag cggcgtgcct
    21841 acacagacat tcaaaaatta tttggtgcag ctgctgccag agttttcttt actagatgaa
    21901 cagcaacaag aaagtggttt tttgctaggg gaaaaagatc cgatacaagt gatgaaaagc
    21961 ggattgacct tagtcgatca gattgatcgc tatatccaag gcatcacaaa ctacggtccc
    22021 ttgttccgtg atatgaaaat aaatggccgt acgatcctat caaaggaatc gattcgccaa
    22081 tggtataaag aaacaaatga acaattacct ttacatcata gactttctct attacaaacg
    22141 aagctcctga aaaaattagg cggtctgcaa aaagacgaaa cacgtcagca atgggtcaaa
    22201 gatctggcgg aagaacagct ccaagaacta tacgcaacag atccaaatct tgaatataca
    22261 gaacaaaagg agcgttcatt acgtaaaaaa ctggccaacc aaatcgtacg taaaagattc
    22321 cgtcgaatcc atcgagggat catgaattat caatttgtca atataacgaa acaatatctc
    22381 cactttctac aaactgtgcc actttctctt ctaacacgac ataaaatcag cgagaccagg
    22441 tggcaggaac atttgacaac tgttcgtaca cacttgcgtc aaagagaatt gcgtcaagag
    22501 gatgctgtac tattcttttt actgatgcgc cgaacatatc cagtgacggt tacacacaaa
    22561 gctcgctata tctttattga tgaaatgcag gatttcgcac catcacaagt ggcattgctg
    22621 caagccttgt tcccaaaagc aaatttgact ttctgtggag atctaaatca aaatgtcttt
    22681 ggaaatgaaa cgatcgttgg atcattggaa gaccttttcg tggaccgtga agtcactcgt
    22741 ttccaattaa cgacaagcta tcgctccaca aaagaaatca ctgattttgc taatcatttt
    22801 attgtgaaag aacatcaagt agaaacaaca gcaagaaaag gagaccttcc tttgctcatc
    22861 caaggaacaa cagatgatat caaattgaat tggttagcag ataccattcg aacgactcag
    22921 ggaaaagccc ggtattggcg tacagcaatc atagctaaaa cacaagaaga atgcgaagct
    22981 ctttatgctc aactgccaga cgagttgaaa caacaagtcc agctgatttt aaatgagagt
    23041 gactttatga agcgttccat tattttactt ccagcctttt tagcaaaagg tctggagttt
    23101 gaccgagttt tcttgtggga tgtagatgca gaacattttt cttctcagca agacaaattg
    23161 atcctttaca ccatgtgtac acgtgcgatg catgaattga ccctttttac ctccaataat
    23221 gaaagtcctt tgttaaacaa tatggatatt tcatcttatg agaaaaaagt actgtaagta
    23281 aaaagacaac tgctatcatt aatgttagca gttgtctttt tatttacaat aataattgca
    23341 gaaaaagtaa ttcaatcatt taaggtcatt tattctatat ataaatccaa atctgtttca
    23401 ggatatttta atttgacaag cgaaataatc attttcagtt cttccatgtt ttctggatat
    23461 tctgggtcaa ataccttgct atgacggcca atcccgccat tgtcgatcaa tcggtaaatt
    23521 cgattccatt caatgaattg gtcaattgat tggaaattgc tgattggata gccgccacaa
    23581 tccaaaatct ctgatacacg aaatgctagg tatgcactat cgatcacttt attttttttc
    23641 gtgtctatct tctcatttct ttcgataaga attttttcag gacgatgttt caagctccac
    23701 tctaatagta gaaagaaagc ctccatccga tactcttctt caaataaccg aaaggctgaa
    23761 tcagaacgac gaaaaagcag cggaatcaga taattttgtc tataaatcag cattggtgcg
    23821 cggtccacca tacactctaa ataacggttc agataccctg taccgacata gtttcctaat
    23881 cgatagcctt caacgccgaa tcttgcgtat ttttgcgcta attttgaaca atcagttacg
    23941 ttcacagcta actcttctac tttgcggtaa ccgcttaaga tacgttcaaa aggttctaaa
    24001 gtgatttttg cttccatatt cttccccgtc catcttccac atacttcata tcatttcaca
    24061 tgatacttat gctctcatca taccacaggt tgaattagaa aagaaaataa atcacacaaa
    24121 aaagcaagac aatctgttag tgagattgtc ttgcttttcg aaaaagactg aatacttttc
    24181 gttaaaactg gttgcttagt cttctaatgc cacattatgg aacacatgct gtacatcttc
    24241 tagatcttcc agtgcatcaa tcattttttc aaatgtttct tgatcttctg gagatagtgt
    24301 tacctcgttt tgagggatca tttggatctc agcgattgaa aaatcagtga ttcctttttc
    24361 ttttaatgct tcttgtatac tatggaaatc cgctacttca ccgtaaacga tgatttgtcc
    24421 ttcttcttcc attacatcgc gaacatcgat gtctttttcc attaggtatt caaggatctc
    24481 gtcagcgtct tctcctgcaa aagcaaagat tgctgtattg tcaaacatgt aagaaaccgc
    24541 tccggaaaca cccatgttcc cgccattttt cccaaatgct gcccgtacgt ctgctgctgt
    24601 tcgattcaca ttgttcgtca atgtatcaac aatcaccatt gagccgcttg gtccaaatcc
    24661 ttcatagcgc aattcagagt atgtttcatc tcctgcacct tttgcttttt cgattgctcg
    24721 gtcaataata tgttttggta cattataagt tttagcgcga tcaatgacga aacgtagttt
    24781 ttggtttgca tgcggatcag gatcacctga ttttgctgcc gcgtagattt caatcccaaa
    24841 ttttgcataa atccggctat tattagcatc tttagcagtt ttctttgcta cgatatttgc
    24901 ccatttacgt cccatatttt cacttcgctt tctgatttga tagtttcata acgcaaaaac
    24961 gtcctgttcc attatacttg tgaatcacga ttctgtgaag ctttttttct ttcttccttc
    25021 attcttctca tttttagtca attatctata ctcggattgg gatttgcccg aaattctgtt
    25081 ccggaatatt gcctcccaat tgatagattt gatcacttct aactaacagt tccgcttctt
    25141 gtgcctcttt ttttccgatt cgggaataaa tagaaatctc ttttttttct tttaagaatc
    25201 ttcttccagc atcggtaaat ccaagtagtc gaagataatt tttattttgt tggacaggaa
    25261 tctcttgctt tttgatattc agcaagacat aacaagataa tcgttggatc cgtgtccatg
    25321 tatatctttt tgtttttacc tttgacacaa aatcctcaaa actatcagca gttgcagctg
    25381 ctgttttcat gcgcgattct attccttcgg tcatctgata gatatctgtc agttccagca
    25441 aagtagaaga taacaaccga taacgcaaat acggccaata agattcccaa gtctgcagcg
    25501 aacaagttga aagatcttct tctgtctgag gcggcacaag tccagctatt ctttttcctt
    25561 cttctaacgc atggcgaatg gctgttgcac tggctatcct ctgatctgtg atgatttttt
    25621 catgatagcc tgcactttta cgtcggatcg gatgtaattc catagggtgg acatacttgg
    25681 cattttcctt tgcataactt aatcccaaga tatgatttgg cgaagaaaaa tcaagcgtaa
    25741 tatcgggata cagactgcga aaaacctcag tcattttttg cggataacta tacgtttgat
    25801 cagacagttc ttgaaatgcc tcttctatcc tatcttgatt ctcttggaca aagcgtccga
    25861 aactgctgta atcaaacgaa gtctcttctt ctgttccaaa acacaaactg tcacagtcca
    25921 gtgtttgcaa gatttttact gcacctttag caaaatagtc agctgactga accgcccatt
    25981 cgacgggaag ctccactact aaatccacac cattttgtaa agcttcattc gcgcgatgcc
    26041 atttatcgat gatagccggt tcgcctcttt gcaaaaaatt cccgctcatt acagcaatga
    26101 cgacctctgc tcctgttatt tttcgtgcca tttccacatg atagcgatgt ccattgtgaa
    26161 aaggattgta ctctacgata atcccgcagc ttttcatgcg catcctcctt catagttatc
    26221 gataaaaaag aaatagagac aagtaaaaaa aggcaaaaat cggaaaaaat acccgaacta
    26281 tataaactat tctcgcaaac acaatacttc tgcgacgaaa agctgcactg caagagcaat
    26341 gcctatatcg ttcggatata taatttatgt tgaagattta ttcttttctt gttaactcga
    26401 gcaggcaaaa ccgctagtct ttgtatgcta caaagaacca gcgctttgat ttctctgatg
    26461 ctgcttcgtc tgtaaaatca gaaaatgctt cgactttcga aaagccgctg ttttccagca
    26521 ttcttaaata actttccaat ggataggtac gctcttgatg tagttcatct tcacgaataa
    26581 atcgaccaga cccttcttgt tcttcaacga aaaaggtaag aaaatgttcg atgctgtgtt
    26641 tctcgcttcc tggataacta tcccacaaaa aagcaaaatt atccccttga taatgatagc
    26701 tatattctgg aaaaacctca tctacttgat aggtggagtg tacgtcaaat aaaaatcggc
    26761 cattttcttc taacgcttga tagacttcat caaacacttg ctgtacctct tgtctatttt
    26821 tcatatagca cagcgaatca gaaaaacagg taattgcctg atattgtccg atttctgata
    26881 aatcgagcat attgccttcc acaaattgga tcgatgcgtc ttcttcatat gctcgctggc
    26941 tggcaatcat caacatctct tctgaaaggt ctaaccctgt cactttatat ccatcttttg
    27001 caaaggcaac cgctaatgct ccagtaccgc atgccagttc caaaatattt tttgtgtctt
    27061 cttgtaaatg acgtttcgaa aaagctaacc attgctgata aagtgtttcg tccatcactt
    27121 catcgtaaat gaaagcaaat gtttcataag ccatatgtta atccaaccat tcactaagat
    27181 cgactagcgg agcatctgac catagttttt ccagattata gaaatttcgt tctggcgcat
    27241 ggaaaacatg tacgatcaca tctccaagat cgatcaatac ccattttccg ccttcttttc
    27301 cttcaatacg ttttacttca tatttgtttt cttcttcttt atcaatgatt tcttctgtaa
    27361 ttgcgttgat ttgacgttcg ctatttgctg aacagatcat gaaataatct gccaacaagg
    27421 aaacatttcg aacgtctaaa gcgataatgt cttctgcccg ttttgaatct gctgcttcaa
    27481 tcgcaatttt taattgttct ttactatcta tgatgatttc ctcctaatat gagcagctta
    27541 tttttttgct acccagtaat tatatgtttc gattgttttt ggataaatct gttgttcttg
    27601 cgcaagcaaa tgggccaatg tatgttttgt ttcaaatgct acagcttcgt ctagatcagc
    27661 ccatgcaatg gctcgtgcat cttgtacccc aggaaaatct cgacctggtt caatatagtc
    27721 tgctacataa atgattttgt caaggagact catcttagca gccccagtcg tatgcacccg
    27781 gattgcatga agaatctctg catcggtgat tcctaattcc cgctctacaa acgaagcgcc
    27841 aacaagacca tgccagattg cattattata attcaataac tccggatcaa aaccgtctct
    27901 tacgattacc attttgaact cctcatctgg tcgttctttt gcataatcat gtgtcaatgc
    27961 agcaatacta gctttttcag gagaagcacc gtattttttg gcaagagcca cggctgtttc
    28021 ttctactcca agcacatgct tgaagcgttg ttcgctcatt ctcatctgta ttttttgcat
    28081 caggttttct ctagaataag cagtatattc attactatag tccatattca tacaaccctt
    28141 cattttgaat ataatcaatt actttatctg gaacaaggta gcggatagaa cagccttctt
    28201 tgatcttttg acgtattttc gtggaactga tgtcgatctc aggtacatct acccaaatta
    28261 caggatatgg agtatccgtt gtgtatcctg gtcgacgtat acccacaaag ttgaccatag
    28321 aagtcagctc atcgatttta taccattttg gcaaatattc taccatatcc ccaccgataa
    28381 taaagtaata atctgtatcc ggattgtttt gcgtcaattc cttcatagta tcataggtgt
    28441 aacttttccc accacgagct aattcaatcg tttcaatctg caaaaaagga ttgtcttcca
    28501 ccgctaattc caacatgttg agtcgatgtt ttgcatcaat cgtctgtttc tcatcaacat
    28561 gaggtggctg ataagaaggc atcaaaaata cgcggtcaag acctaaattc cggccagctt
    28621 gttcagccat cactaaatgt gcaaggtgaa cgggattgaa tgttccgccc aagatcccta
    28681 cttgcttttt cttctctaag aattgaggca tttcttcagg aaataattgt gaacgaacaa
    28741 atgtcttagc ttgcgtattc atcatggtca ctccttatat tgcttttact tcttttgata
    28801 gcctttgata cttttctttt gtggaaggtt tgtataatac aataacacgt ccaatgattt
    28861 ggacgatttc gcaatctatt tctttttcta atacttgagc tgcttcttct gcaatctcat
    28921 ctgtattttg aagtaacgat actttgatca gttctctttt ttctaaagct tcttcaattt
    28981 gaacgatcat tgctgaattg atcccacctt ttccgatttg aaaaatcggc tgaagatgat
    29041 gcgctttgct acgtaaaaaa cgcttttgtt ttcctcttaa actcataatt ttccttcttc
    29101 cttaaatcaa tgctttgcgt ttcaatacat ctacaccctt tggcgcccag cccgcaatta
    29161 ctactggcgc tgttacagtg atccagccta gaccggcaaa aacgatgtct gttttttctt
    29221 tcacagaaaa ctcaaaacga acaagctccg gaaatgcctc gacttcatca ggacgaggag
    29281 gctgtaataa tccacctaca tgtttttgat aaaattcgtc tgctttttcc agtttcgttc
    29341 gatgaatatt tacatcattt gacacataag caataaatga agcacgattg ccgctgataa
    29401 aatcaaatct tgcaagtccg cccaagaaaa gtgtttgccc ttcattcagc tgataaactt
    29461 taggtttgat ttcttttaac ggtgcaatga tccgcaaatc ttttttacct aagtagtgcg
    29521 ccatttgatg gcgatggata attcccggtg tatcaatcaa aaaatgcccg tcatctaaag
    29581 gaatctcgat tttatccaag gtcgttcctg gaaactgcga agttgtgatt acatcttgta
    29641 ctcccgctgt atttttgatg atttgattga taagcgtcga ttttccgaca tttgttactc
    29701 cgacgatata gacatcccgt ccatcgcggt attcttcgat tttttctaat agttccgtca
    29761 tctcatgaga tttcttagca ctagttaata atacatctac tggacgaatt cctgcttcgt
    29821 aagcacgttc cttcatccat tgtgttaatt tagttttttt caatgattta ggtaatatat
    29881 ccactttgtt cccaactaaa agtactggat tgtcaccgac aaaacggtgt agtcctggga
    29941 ttagtgaacc attgaagtca aaaatatcca ccacattgac gatcaatgca tctttttgcc
    30001 ctaattcatt cagtaagcgc aaaaagtcgt catccgtcaa tgagacatct tggatctcat
    30061 tataatggcg taatctgaaa caacgctgac aatagacttc cccggaagct aaaccttttt
    30121 ccaaagccgt ttgcggcgtg tatcctaatt caccgggttt gtttgtttgt ataacggcac
    30181 cacagccgat acattgtaat tcttctgtca ttcgattcca cctcgccagc ccatatcagg
    30241 gtgttttgct aatagatagg ccataattct tttttcccaa aaacgattaa attgtgtctt
    30301 ccaactatct gttgcgataa tgggttttac aaggatgcta cgtatccctg cacgattggc
    30361 tccacgtata tcagtcataa tctgatcgcc taccattact atctcatcat ctgctaaatc
    30421 caattgtttc tttgctatgt tgatccctct tgctaaaggt ttcattgctc gtgcaacata
    30481 caaaagatca aatttttcaa tcgctcgcgc gacacgtttt gaattattgt ttgaaacaac
    30541 aacaacaggg attcctgcat ttttcatttc taaaatccaa gtaagcaact cttctgttcc
    30601 atctggatta ttccatgcaa tcaacgtatt gtctaaatcg gtcaatactg ctttgatgcc
    30661 tagattcttt aattgggcag gtgtaatctg atagatggct tctaccatcc atgttggttt
    30721 gtaatttgaa aacatgctgt ctcctcatct gcaaaaaatg aaggagcaca taaagtactc
    30781 ctcaaccccg tattatactg catatcagca aaaaaaacta cctctatact cgttcgtctt
    30841 tcagaaaaag catttcttta caaaatgacc aaaaataaag attgatcaca gaaaaattta
    30901 gaaacaaaaa acaactaata ttggcggaac ctcttgtatc gtttttccag taatttatgc
    30961 tgatctaatc gaacaagttc cgtcaatctt tcaatcaacg cttttttcat aatgtgtgcg
    31021 actttatatc gtggcaactg ctcgccgttg aacgtttcag gaataactcg atcaacgatt
    31081 cctaactcgc gtagttctgg cgcagtaatt ttcatcaact cagctgcttc tgcggcgcga
    31141 ctaccgtctt tccacaaaat cgacgcaaat ccttctggag aaagcacagc ataaatcgtt
    31201 tcttccagca tccagacttc atccgctaaa cctagagcaa gggcaccgcc acttccacct
    31261 tcaccaatga tgatggcgat gatcggtacc tttaaatcag acatttcgag cagatttctg
    31321 gcaatagcct ctccttcgcc gcgctcttct gctcctacac cgcaatatgc acctgctgta
    31381 ttgatcaagg taatcaccgg tctattgaac ttttccgctt gtttcatcag tcgtaaagct
    31441 tttcgatagc cttcaggatg gggagaacca aaatttctgc ggatattttc ctgcagatcc
    31501 cgtccttttt gaataccgat cactgttacc ggtttgccat ctaatcgagc gattccacca
    31561 acaatcgctt cgtcatctgc aaataaacga tcaccatggc attcctcgaa agaatcgaag
    31621 atctcttcaa aaaaatccaa gcttgtccat cgttctttag ctcttgctaa ctgaacgaca
    31681 tcatgtgctg tcttatccac gatctatcca tcctttctgt gtatgcaatt caagaagcgt
    31741 atggattttc tgtttcaatt ccatgcgggg aacaatctga tcgacaaaac catgagataa
    31801 taagaattca gccttttgga aatcttctgg aagttcctgc ttgatcgtct gttcgatgac
    31861 gcgtcttcca gcaaaaccga tcaagctttg gggttctgct agaataatat cgccttccat
    31921 tgcaaaactg gcagttactc ctccggtcgt cgggtccgtt aaaacagtta gataaaaaag
    31981 accttcattg ctatgccgtt tgacagcagc agagattttt gccatctgca ttagagaaaa
    32041 gattccttct tgcatccgtg cgccacctga agctgtgaac aagacgactg gaagactttc
    32101 ctttgttgct cgttcgaata atctggtgat cttttctccg acaatcgttc ccatacttcc
    32161 catgataaaa ttaggatcca tcactccaat aatgaaggga atcccctgaa tggttgcttt
    32221 accagtgagg actgcttcat gaagtcctgt tttatcttgc atttttttaa ttttttccgt
    32281 atattcggga aatgctagcg gatctttggt tacaagatcc gtatcccatt cttcaaaact
    32341 tttttcatca ataatcaaag ctagacgctg ccatgcaccg attcgaaaag cgtatccgca
    32401 atgagggcat actttttctt caccgatgtc tttcgtataa aggatatgtt tgcaatttgg
    32461 acactttgcc cacatgttat caggaacaga tggcgagtta gcaggtttgc tctctctatt
    32521 aggattgatc cgaatatatt tctttttctt aaacagagcc atctatgcgc ctcctatctc
    32581 cgtttctggt gtccaattcg gtaaaaattc ttcttgtaaa aatgctgtgc tgtaatcacc
    32641 tgctatgact gcaggatgac taatcaaatc catctgaaat tctgcgttcg tgatgattcc
    32701 ttctgtgata aattcactta aggctcgctg catcttcatt aatgcttcaa aacgcgtatt
    32761 tccatggacg attatttttg caatcattga atcataatat ggcgggatcg tatatcccgg
    32821 gtaaactgca ctgtctactc gcagtcccat cccacctgct ggaagcagta agttttggat
    32881 cttccctgga gaaggagcaa aatggaaagc aggattttct gcattaatcc ggcattcgat
    32941 tgcgtgtcct tggaatacta cttcttcttg acacacattc aaaggctcac cggctgctat
    33001 ctccacctgt ttttttacta aatcgattcc tgtgaccatt tctgttactg gatgttccac
    33061 ttggattcga gtattcattt ccatgaaata aaaatcgcct tcttcatcca tcagaaactc
    33121 gatcgttccg gcattttcat aattgactgc tttagctgct cgaacagcag cgtctcctag
    33181 tgcttctctt tttgtttgtg agatcactac agaaggagat tcttccagta ctttttgatt
    33241 gttgcgttgt aaagaacaat ctcgctcgcc taaatgaatg acatgaccaa atcgatcacc
    33301 taagatctga acttctatat ggcgagcagg ataaatgatt ttttccaaat acatatcatc
    33361 atttccaaat gccgctgctg cttcttgctg agctgaagaa aaatgctgtg ggagctcttc
    33421 ttttgattga actttccgaa tgcctttccc gccaccacct gcagctgctt tcagcatcac
    33481 tggataacca attctgtctg ctatttccaa tgcttcttct actgtagata atacaccagt
    33541 acttcctgga atgactggga catttgcttc ttgcatcaat tgacgcgcat tgatcttatt
    33601 tcccattgca tcgatcgttg cacttttagg accaataaat gtgatattgc actcttcaca
    33661 catggaggca aatcggctat tttcagataa aaaaccaaat cctggatgaa ttgcttcggc
    33721 ttttgtcacg attgcagcgc tcagtacttc ctgaacattc agatatgaat caacggcttt
    33781 tgccgggcca atgcagattg cttcatctgc taactgtgta tgaagtgctt cggcatctgc
    33841 ttctgaatat atcgctacgg tttggatccc tagttcgcgg catgcacgaa tgatacgtac
    33901 agcgatttca ccgcggttag ctatcaatac tttagaaaac atatttcacc tatccaatca
    33961 taaaggttaa ttccgcttcg gctacttttt taccgtctac tttagcgatt cctttgccta
    34021 ttccggctga agctttcact ttcaatatct caacttcaag gtataaggta tctcccggtg
    34081 taactttctt acggaatttt gctttgtcca atccgccgaa ataagccgtc tttcccttga
    34141 attgttcaag agaaagtaat gcaactgctc ctgcttgagc cattgcttca acaatcaata
    34201 cccctggcat aacaggttct tctggaaaat gtccttgaaa aaagggctca ttgatcgtta
    34261 catttttctt agcaacgatc cgttctcctt caaccatttc ttccactcga tcaatcaaaa
    34321 gcattggata acgatgtgga atgatttctt ttatttcttg tatgttcatt gttttccctc
    34381 tttcctgctt tgcttatttt tgctgaatcc taaagagtgg ctgtccatat tcgacaactg
    34441 actcgttttc tacaaggatt tctgtgatca ctccgtcggc ctcactagtt atctcattca
    34501 tcagtttcat cgcttcaata atgcagataa cttctccttt ggcaacttga tcacctactt
    34561 ttttgaaagc tggtttgtcg ggcgctggtt gcagataaac gattcccacg attggcgaaa
    34621 caacctcgat tccatcaaat actgccgatt ctttttcttt cattatttct ggagcagttg
    34681 ttgcttgttc agatatgaca ttgactggct ccgaaactgg caacgtttcg tttgtttgaa
    34741 ccatattcat gcctcgactt gttttatttt tattcatata caattcaaat tgaccttcac
    34801 gcaaatcgaa ttccgttagc gaggattgat caaattgact gactaattct ctgatttcat
    34861 tgatatccaa aattattcct cccagcgttt catgcacaga accgcattat gtccgccaaa
    34921 ccctaatgaa ttactcattg cataagtaaa acttgcaggt ttgctttcgt ttttgacaac
    34981 tgtcaagtca atctcaggat cttgtttttc tacattgatc gtaggtggga taaattgatg
    35041 ttctaatgcc agcaaagttg ccaaggcttc gatcccgccg gctgctccca ataaatgtcc
    35101 agtcatcgat ttcgtgctgc tgacgtaagt atctctgaaa ttttcaccta atgcgatttg
    35161 gattgctttt gcttctgcct ggtcattggc tggtgtactt gttccgtgag cattgatata
    35221 tccgacttgt tccggctgta caccagcttc ttccatcgca agcttcattg ctttagatgc
    35281 accagaacca tctggagtag gagctgtcat atggtaagcg tcacagtttg caccgtatcc
    35341 aacgatttct ccatagattt tggcaccgcg agcttgtgca tgttctaaag attcaagaac
    35401 tagaacgcct gctccttcac ccatcacaaa accattccga ttttcgtcaa acggaatcga
    35461 accacgatta ggatcagttg attctgagag tgctgttaaa gctgcaaatc cagcaatccc
    35521 catctcacaa atcgttgctt ctgttcctcc agcaagaatg acatcagaat agccatgttt
    35581 gatgttacgg aatgcttccc caattgaatt cgttccgcta gcacaagctg ttacgatagc
    35641 tgtacaaata ccttttgcac ctacacgcaa agcaatattt ccagctgcca tgttggcaat
    35701 cgccattggt acgaacattg gagaaactcg ttttgcacct ttttcatgta gacgaataac
    35761 ttggttttcg attgttggaa gaccaccgat cccagatccg atgatgacgc caaaccggtc
    35821 ttgattcatt ttttctttat ctaaaccgct catctccatt gcttctaaag cagcgtagat
    35881 tccatagatc gaaaacatat ccattcgttt gctatctttt ttaataaaat atttatcgta
    35941 agggaaatct ttgacttcac ccgctaaggt aatccctgtt tctgaagcat caaatttagt
    36001 gatcggtgcg atgccattcg tcccctcttt taagctattc aaaaagctgt ctgcgtcatt
    36061 tccaataggt gaagtgactc catagccagt aattaccact cgattcattt gtttgctctc
    36121 cttttcttat ccgtgcatga ccaatccgcc atcgacattg atgacttgtc cggtgatata
    36181 tggattttgt gctaagaaaa ctgctgtttg tgcaatatct tctacttgtc cgaaacgctg
    36241 catcggaatt tgcttttccg cttgttcctt gactttgtct gctaaaactt ccgtcatatc
    36301 agttgtgatg aatcctggcg caatggcatt acatgtaatg cctctagttg cagcttctcg
    36361 tgccacagat tttgttaatc ctactacgcc agctttacta gctgcataat ttgcttgacc
    36421 aatatttcca atcaacccag atacactaga gagattaatg atggcccctt ctcgctgctt
    36481 catcattttt ttcaatacgt gctgcgtcat attgaaggtt ccaatcaaat tgatatccag
    36541 acattttttg aaatcttctg catccattcg catcacaagt ttgtcatttg tgattccggc
    36601 attgtttact aacacatgga tcgatccaag cttttcttct gcttctttga tcatttgtcc
    36661 cgctttctca taatcagaga tgtcaccgga aactcctacg cattttacac cgaatgcttc
    36721 gatttcttct atcttttctt ttggaatctc tccgcgacca ttcaaaatga tatttgctcc
    36781 agcttttgca aaagctaagg ccatcgcttt gccgattcct cttgtactac ctgtgataaa
    36841 tacatttttt ccttttacat ccataacgtt cctccttata gtattgctat tgtttcatca
    36901 aatgtctgct tattctcaac acgcagaact ggtattgttt tatcgatttt tttcataaat
    36961 ccgcttaata cttttccggg gccgacttcg atgacttgtt cgatgccgat tgtttttaac
    37021 ttatggatac tctcatagaa acgaacaggt tgcatgactt gctgttcaag tagtcccgcg
    37081 attgtttctt tcttcattat ttccgttgtt gtgttgctta tgataggaaa agaaggttca
    37141 gagaattgaa tctgacttag gtccttcgcc agtttttttg ctgccggttc taaaatagct
    37201 gtatgaaaag gcccgctgac atttagaggg atcattcttt tgaacccttt ttcttttaat
    37261 agtaaaacag cttcgtctac tgctttttct tcgccaccaa tcacgatctg ctgaggtgta
    37321 ttataatttg caggagatac gatgccgtac ttgctagctt catgacagct ttcctcgatc
    37381 gtttcaatcg gcgcattcat cactgcaacc attttcccgc ttccagctgg ggtagcttct
    37441 gtcatataag cgcctctttt tgctactaac gcaactgctt cagtgaagga tagcgcatta
    37501 ctagctacta atgccgaata ttctcctaaa ctcagtccta aagctgcatc tgggatgatt
    37561 ccatgctcct tcaataagcg ataatacgcg atgctgactg ttagaatagc tggctgtgta
    37621 tattgcgtct gatccaaacg ttcattttct gtaaagcaaa gttcagccat atcgtagccg
    37681 agaatctcac ttgcttcatc aaatgtctgc tttacaacgg cttcttcata taaatctttt
    37741 cccatacctt gatattgtgc accttggcca ctaaataaga atgctgtttt catgtttttc
    37801 tccaatatat ccagaatata tgtttgattc ttcctattca aaaaggccga gacattccta
    37861 tttcaggaaa tgtcccagcc cccaacctaa ttttaatgat tatgcagttt gtttttctac
    37921 gtaagtcact aaatcttgaa ccgttttgat tccgtcttct gtttcgattt tcacgtcaaa
    37981 ttcatcttca atttcattga tgatttggaa taaatccaag ctgtcagctt ctaagtcttc
    38041 ttggatgtca gtagtcaatt tgatttcttc agtttctttt cctaattctt ctgcgatgat
    38101 ttcttgaatt ttttcgaata ccataataat atattcctcc gatattgttt gctttttatt
    38161 tttataattt aacagtctac aactccatga gaatacttcc ccatgttaaa cctccgccat
    38221 agcctgtaaa tattactttc tgctgttttc ctaaggtgat ctttccacta gaaactgctt
    38281 catccaataa gatagggatg cttgcagcag atgtattccc atatttatcc atattggtca
    38341 ggaacttttc ttgcggcatc tttacttttc gggcaatttt ctcaataatt ctgaggtttg
    38401 cctgatgcaa aagcagataa tcaactggtt tgtctttcat gacttcttgg atattgtttg
    38461 caacgtctcg tacggcaaaa tcaaaaatat ctctgccagt catttgcaaa taatacgaac
    38521 cttctgaatc ttctgaatag aacggatttt tattttgctg gtagccagcg gtcaatgagc
    38581 tacttctggt accgtcagct gctaattttt ctttcagcaa ttttttctgt ggattcgctt
    38641 ctaagagaat cccacctgct ccatcgccaa acaacacagc agtcgtacga tcagaccaat
    38701 cgattagctt agatagtgtt tcaccaccaa tcaccagtcc cttagttgag ccgcagcgga
    38761 tcattttttc agccatgctt aacgcataaa caaatcctga gcacgcagca ctgatatcaa
    38821 aagcgatagc atgagttgct cccaatttcc cttgtacttg tgctgctaca gatggtgtcg
    38881 tgtaatcggg cgacattgtt gctactaaaa taaaatccaa atctttaggg tttagatttt
    38941 tctgttttat caatttttcc gccactaaaa tgcataaatc agaagtctcc tgatttgtta
    39001 cacatcttcg ttcacgaata cccgtccttg acgaaatcca ttcatcagag gtatccatca
    39061 tcttggaaag atcattatta gtaataatct tttcaggaag gacgctggct gttgcagtaa
    39121 tcattccaaa ttgttccatt aaatatcctc acttatagtc ttgcaagaag tcgtgcaagt
    39181 ttttcagtgc atccagcaag gcatgctgtt cctccgtagc cattccgtct aagatgttct
    39241 tgaccatttc acgatgaaaa tgctgatgga cccgaaatag taactttcct tttttcgtta
    39301 gtcccaactt tacaacgcgg cggtcatctt cactgcggat acgttcgaca tagccttttt
    39361 ttactaactt gttaatagca gtggtcaagg tcccaacagt aattgatagt tctttggcta
    39421 cttctgaagt tgtttttttc ttgtacatcc cgattgcctc gatcgtgtgc atctctgtga
    39481 ttgacagatc tttgaattga gattttttca gctcagactc ttcgattgtc aaaatatcat
    39541 tgaagacact aacaagataa tcatttactg tttttaaatc tggttccatg ttccaccgtc
    39601 cactaattag tttgattatc aaatcttttg atgttcaaac tatatcttaa cttttttcaa
    39661 aatgcaacct taaaagatca tttttttact atatgagctt tttttaagat tttactcatt
    39721 taaaacaact gataaatcag catttataat ttcttttatt agaaaaatca tctatctcac
    39781 atattttgat tatcaaagta ttttctgtga acagaactat agaattccct aaaacttgtc
    39841 cattatttca aaatttgtta tagtcttttt attcaaagcg taaaaggaga tcctatgtta
    39901 aaagaaaaaa tgaaaactct ccccatgctg ccgggtgtct atcttatgaa agaccgagat
    39961 ggtaaggtca tctatgttgg taaagcaaaa cggctcaaaa atagagtaag cagctatttt
    40021 catcagaata aacagcattc aaaaaaagta ttacgtatga ttcatcatat aacagatttt
    40081 gatttcgtcg tagtagacac ggaattagat gctttattgc tcgagtgtca attgatccaa
    40141 cattaccgtc ctttttataa ccgacaaatg aattatttca gtaattataa ttatgtacat
    40201 attaccaata agggatttgt attaacagat actcctacgg ctcgaacata cgggcctttt
    40261 cgtctctata aaaaaatgcc gtctattttg cgtataatgg aagaaactta tcaaatgcct
    40321 tggttgtctg aaattagttt gttagctttg cgagtccagc ttcctgacct acaggaaatg
    40381 acttttgaac agaaaaaaaa ggaactccaa gggctgtttc aaggccgaaa taaaaagcta
    40441 ctgacttact tgaaaaaaag acaacaacat ttcatctatc agttgaattt cgaaaaagcc
    40501 ggtatgcttc aaaaagatat cgaattagtt acttatttta ttagacggat ccaggaacaa
    40561 aagcagtttt taagaacacc atcgctcacc ttcagcatgc cattagcagc agatgagagt
    40621 cagaaaaagc actacctcgt ttgttatggt caacttgcag aaacaatgat tacctctggt
    40681 gacgtttctc ctgacttcta ttatgaaaag aaagaagctc atttatcttt gaaacgtcaa
    40741 ttgtcaaaag aagaaatcga tcctgtacaa atcttgatca gttaccgcaa aaaattagaa
    40801 aaagaacagt ttgaaattga actgttaaac aaaaaagaag ctgaaaagca actaaattag
    40861 ttgcttctcg gcttctttta ggcatcttca acttcaaatg tcaattatcc taaaatttat
    40921 tggattaagt catagatttc catcgctacg atatcgatat tatcaaattc gtattgctga
    40981 tgagtatctg tttcagttaa ttcaaatgta tcggtcgctt tatcataagt tactgtacac
    41041 ttctctacgc cttctttttc aaaacggcga acttgcagtt cattatctgc tgactcgacc
    41101 atagcctcca gtcgttttat gattgcgact aattgtgaat gtgtcatcgg aggtcctcct
    41161 tttcttattt ctgttatatt gtatcaaaag catagcctac ttgcattgat tttctctaaa
    41221 aaaactcgtt ttttatgatt ttttttctgg tatttttcct tcaggccacc aaagtttgat
    41281 caaagcttgg gttccgtcat tctcaaaacc tttatctgcc aactcttcat atagtttcaa
    41341 tgcttgggta gttgctggca atacaagatc cattttttct gcttcttcta atgcaatctt
    41401 taaatctttg ataaaatgtt tgacaaaaaa accaggtgtg taatcttctt ttaaaatacg
    41461 aggagaataa ttgcttaaag accagttagc tgcacttcca cctgaaagcg tctcaatcac
    41521 tttctttaaa tcaagtccgt ttttttgtgc atagacaagc atttccgtca ttcctgtcat
    41581 cgtacctgca atcatgatct gattagccat ttttgtatgc tgacctttcc cagcagaacc
    41641 atgcaatgta aatgtcgtac caaattcttt gaataaaggc agtacttgat cataaacggc
    41701 ttcttctcca ccgaccatga tcgtcagtgt accattcttt gctcctaagt caccaccgga
    41761 taccggtgca tctaacgcat ctgcgccttt ttcttttgct gtttttgcaa ttttttctgc
    41821 caggcttggt gtacttgtag tcaaatcaac taaaatatgt cctgagatat ctgcagaaaa
    41881 aatccccgac tgtccatagt agatttcttc tacatctttg gggtaaccta ccattgtaaa
    41941 gagaatatta ctttgttctg ctaccgcttt tggtgtatct gcccagatag ctccttctgt
    42001 tactaaagga tcagcttttg cttttgtccg attatagaca gctacttcgt gtcctgcttc
    42061 tagtagatgg cgtgcgacag cacttcccat gacgcctgtt ccgataaaac caagtttcat
    42121 tttttcgacc tcctaaaaat caaaaatcct tgcttctatg ctagtatacg ctagaaacaa
    42181 ggattttttc ataaaaaatg tttgaatttt atcttttaaa tgaatttaat tttattttga
    42241 ttcgttcaat cgagtcttct tcttcttttc ttcgcatctc ttcttcatga taaacaacca
    42301 tgtcttgata aaattcgatc atagcttcgc cgaaatgtgt agatgaaata tcataaagtt
    42361 tagcttctaa aacttttgga tctttaggaa cttcactgga aatataatca ataagtgctg
    42421 gtgcaaagtc ttcgtcggtt tcaaaagttt tccctaatga aggatgatcg aacaatcggt
    42481 tcaaataagc atttccttcc acgacacaag gtgttccggc tgccatcgct tctgtataag
    42541 taagcccttg tgtttctgaa gtagaagcac tgacaaaata atctgccgct ttataataaa
    42601 gtgctacatc attgttgtcc acttctcctg tgaactgcac aaattcttct aactgcagtt
    42661 ctgagatcaa ttcctctaac tcttctacat aaggtccttt tcctacgata actaatctgg
    42721 cgttaggata agcggagatg acctgaggaa acccattaat caaggcttgg atatttttct
    42781 cataagaaat cctgcttaaa gaaagaatca tcaaatggtt ttcctgaaga cctagtgact
    42841 cccttaattt gctgatatcc tgctgagtga tatcagaacg tttgaatttt tcaatgtcga
    42901 taccagtagg aatcacgcga agcggtgcta ttacaccata gctgcgtaat gtatcaataa
    42961 cacgttcact tggacaaact acacctgtcg tatgatttgc aaataatcta gacaagtatt
    43021 ttacatggga ttgcctgatc acttttcctt taccgatata atgaaggtag tcttcataca
    43081 tcgtatggta agtatggatc agaggtattt tcaacttctt agctaccatc ttcccaagta
    43141 tccctgctcc gaattctgta tgggtatgaa taagatctag ttctagttct ttggcaacca
    43201 aataagcata ccacatgcct ctaacaacaa ctcttcgatc cttgaaagaa ataaatggta
    43261 cacttggcat tcgaatcaca tctttttcca acttatccgc attaggatcg gtcgttgtaa
    43321 aaatatagac ttcatgccca tgtctttcta attcttgttt taatgttttg atcgatgtag
    43381 caactccgct gacttgcgga aagtaggtat cggtaaaaaa gccgattttc atgtttttcg
    43441 cctccaaact agtccttgac ctgatttact ttttttaatt tgctagagac tttttcattc
    43501 agtacacttt cgtatacatt tttaagttct tcaccgattt tattgatact tcgctctttt
    43561 gctgtttgat aaccggcttg tgtcgtactc ggtagttctt gattggtaat ctgttggatc
    43621 agtcggataa attcttcgtt tgtcttcccc atatagcagt tcttgctatc ttctaaccag
    43681 ccattataca ctggaatatc tcgaacaagt acgttttgtt tgcttgctaa agcttctaaa
    43741 acaacgatcc cttctgtctc ttcataagaa gggaaaaaga atagatctgc acctgaatac
    43801 gcaccttcta tgatctctcc acgaatgtaa ccaggaaaca ggacattttc aggatgatct
    43861 tcttttacaa ttttccggat gttccgagga atcgagtaca tgggaacatg accaaaccaa
    43921 ataaatgtgt attcgggcat cttcttagca atttctacga aatcaatgat tcctttacgt
    43981 tcgaaaaaca aaccgacaca aatgattact ttttgatccg gagacagttt gaaatattct
    44041 ctgaactttt gttctttcat tggatcaggg tgatatttct ctaagtcgat cccattggaa
    44101 atagcttgaa tcggcacacg gataccatag ctttccaaca actgttttga ataaggtgtt
    44161 ggcgtgatca gatagtccgc tttttggtac aatcctacca gatatttttt tacgatagga
    44221 gaaagctggt tcgatccgat aaaggaattt cggaaatctt cctctgtaga atgcgcatga
    44281 tagacaactt tttttccttc tcttctggct ttattgacca tattatgact attgattccg
    44341 tatgtattga tgtgcaggat gtcataatct tctttttcat ctagtgtata agagataccg
    44401 acttccgtca gagcacgttt ttgatgatca agcgcacgcc cgattccaga ttttgcaagc
    44461 atcttttcac tttcaaaata taataatacc ttcaccttac gtcccccttc acttatatag
    44521 tataacatag cctacaaact gtcactcaaa cttaagccct atttttgtct attcttactg
    44581 acaaaaacgt tttcttaaaa aagaacaaaa aaactggcgt agctctttta caagccacac
    44641 cagcttttga tacgttgttt attttacata ttcatgaaca agttcaacga cttcttccat
    44701 catatcgcat tctttcaatg cacgatcagc aagttcagcc attttcgctg tgtccaagcg
    44761 tttcattaaa ctacgcgttt taagaataga tgtcgcactc attgagaact catctagacc
    44821 catacctact agcaatggaa cagctgtttg atctccagcc atttctccac acatacctgc
    44881 ccattttcct tcagcgtgtg ctgcatcaat tacatttttg atcaaacgta aaattgatgg
    44941 gttatatggt tggtacaagt aagaaacgcg ttcgttcata cggtctgctg ccattgtgta
    45001 ttgaatcaaa tcgttcgtac ctacagagaa gaaatctact tcttttgcaa acttgtctgc
    45061 taagactgct gctgctggaa tctcgatcat gatgccgact tggatcgtat cagatacttc
    45121 cttgccttca cttatcaatt tttgtttttc ttcttcaaag atcgcttttg ctgcgcggaa
    45181 ttctttgagt gtagctacca tagggaacat gatacgtaaa ttaccatgaa cagatgcacg
    45241 aagcaatgca cgcatttgtg tacggaacat ttcgtcgcct tgttcagata aactgatacg
    45301 caatgcacga tatcctaaga atggattcat ttcatgaggt aattgcagat atggtagttc
    45361 tttatctcca ccgatgtcca ttgtacgaac aactacaggt tttccttcca taccttctaa
    45421 tacagctttg taagcttcat attggtcatc ttctgttggg aagtctggag aatccatata
    45481 caggaattca gtacggtaca gaccaactgc ttctccacca ttattatgga caccaactag
    45541 atcttttggt gttccgatgt ttgcagctaa ttcaaaatgc ttgccgtcag ctgtgacagt
    45601 ttctgcattt tttaattttt cccattctgc tttttgtgct gcgtaatctg cacctgcttt
    45661 ttcaaattca gctttttgtt catctgtagg atcgatgatt acatcgcctt cgatcccgtt
    45721 gacagccaaa atatcgcctt ctttgacttt agcagtaatt tcttttgtcc caacgattgc
    45781 tggaatttct aaagaacgtg ccatgatagc agaatgtgaa gtacgtccac caatgtctgt
    45841 tacaaacgct tttacaaaat tgcgatctaa ttgtgctgta tcacttggag tcaagtcatg
    45901 tgcaacaacg accacttctt cgttgatcat tgatggattt ggtaaagtaa cgcctaataa
    45961 gtgcgctaaa atacgtttag caacgtcacg aatatctgca gcacgctctt gcatataagc
    46021 attatcttcc attgcttcga acataccgat atacatatcc gttacttctt ttagcgctga
    46081 ttcagcattt acgctgttgt ctttaatatt ttgcttgatt tgacctacca tttctggatc
    46141 tgaaagaacc atcaaatggg catcaaatac ttgcgcttct gcttcaccta agctttgcgc
    46201 tgctttttca cgaatttgct gcaattcttc agtagattta gctaatgcag catccaaacg
    46261 agcttcttca gccgcagtat cttctactgt tgccttactg aatgttaaat ccggttgaac
    46321 tagcaggtaa gcttttgcaa cggctacacc gtcactagcg gcaatccctt ttagcatttc
    46381 aaccattatt cagataagcc ttctttcttc attgtttcaa cgattgctgc cattgcatca
    46441 gcttcgtcag caccttctgc agtaatagta acatcagaac cttgacctac acctaaagac
    46501 ataacgccca tgattgattt caagtttact gatttacctt tatactctaa gtttacatca
    46561 gagttaaatt tgcttgctgt ttgtactaat agtgtagctg gacgagcgtg gatcccagtt
    46621 tctgctacta cgtgaaattc tttcttttcc atattaatcg gtctccttta agtgagtgtt
    46681 gtttttatgt gagggttttc ttttttagta attcagagaa tcctaacaaa tgccaccctt
    46741 tcatctgtaa agattaacat tttttttcgt tagatacaac agttttcatt caatttcaga
    46801 taaaagtatt caaattattc cggattcttt ttcatccttt tcttcacatt ttataacaaa
    46861 cgtgtttatt tcctttttct tgtcgctttc tcttctcctg acgtttatca ttctttcctt
    46921 tgaccctctt tgttttcata tgaaacgaat tacttgcttc cctttttatt tttagtataa
    46981 taagagtcaa aggtcaggaa tggtcaatag agatttcacc ttttctacct cataaatctc
    47041 ttaaaaaact aggggttatt cttttacctc atgaaaaacg agatgtaaaa tatggatgta
    47101 cccatttttg tgaaaggacg tgaatgattc atgctttgtc aaaactgcgg caagaatgag
    47161 gcaacgattc acttgtatgc cactgtcaat ggtcagcgga cacaactcga ttactgtcag
    47221 agctgttatc aaaaaatcaa aaatcaacaa aatggaggtc tgactaatat ggcccaaaat
    47281 gatccatttg gatttggcag tttggacgat cttttccgtt ccatgtctcg ccaaatgcaa
    47341 cagcaaggaa attatgagca aacaccacca acacaatttg gcggaaacaa caacttcaat
    47401 ggtggtcagc cacctcaagg caatacagaa ggtttattgg gagaatacgg aatcaatatc
    47461 acagaacaag cacgacaagg tgatatcgat cctgtgatcg gacgcgatga cgaaatcaaa
    47521 cgagtcattg aaattttaaa tcgccgaacc aagaacaatc ctgtcttgat tggagaacca
    47581 ggtgttggta aaacagcagt tgttgaaggt ttagcacaaa aaatcgtaga tggtgatgta
    47641 ccgcaaaaat taatggacaa agaagtcatt cgtttagatg tcgtatcttt agtccaaggt
    47701 actggtatac gaggacaatt tgaagaacgt atgcaaaaat tgattgaaga gatccgtcaa
    47761 gcagaaaatg tgatcctatt catagatgaa gttcacgaaa tcgtcggtgc tggttctgct
    47821 ggtgatggaa atatggatgc tggtaatatt ttaaaaccag ctttagctcg aggagaattg
    47881 caaatggttg gtgctactac cttaaatgag taccgcatca tcgaaaaaga cgctgcttta
    47941 gaacgtcgta tgcaacctgt acgggtagat gaaccaactg tcgaagaaac gatcagtatt
    48001 ttgaaaggtt tgcaaaaacg ttatgaagac tatcatcatg taaaatatac tgatgaggcc
    48061 atcgaagcag ccgcaacttt atccaatcgt tacgtccaag atcgcttctt gccggataaa
    48121 gccatcgatt tgctagatga aacaggttct aagaaaaact tgacgatcca aatcgttgat
    48181 cctaaaacaa tcgagaaaaa actgcaagaa gcagaagaac aaaaagtttt agcttctcga
    48241 gaagaagatt tcgaaaaagc agcttattat cgcgatcaga tcaataaact tcaaaaaatg
    48301 aaagaacgtc agctcactga agaggaaaca cctgtgatta ccgaaaaaga tatggaaaaa
    48361 atcgttgaac aacggacagg tattccagtg ggtgaattaa aagaaaaaga acagacacaa
    48421 ctgaaaaact tagcagatga cttgaaagct catgtcatcg gacaagataa cgctgtagat
    48481 cgagtagcga aagcgattcg ccgaaaccgt gttggattaa acaaacagaa tcgtccaatc
    48541 ggctccttct tatttgttgg accaactggt gtaggtaaaa cagagcttgc gaaacaactt
    48601 gcctacgaac tattcggttc acaagattca atgattcgtt tcgatatgtc tgaatatatg
    48661 gaaaaacata gtgtctctaa attgattggt tctcctccag gttatgtcgg atacgaagaa
    48721 gctggtcaat taacagaaaa agtacggaga aatccttaca gtcttgtctt gttagatgaa
    48781 gtagaaaaag ctcatccaga tgttttgcat atgttcttgc aaatcttaga tgatggtcga
    48841 ttgacagatg cacaaggaag aacggtcagc tttaaagata cgatcatcat tatgacaagt
    48901 aatgccggaa ctggtaaagt agaagcaaac gttggttttg gtgcggcacg cgaaggtgtt
    48961 actcgttctg tattgaacca attaaacaac tactttacac cagaatttct gaaccgtttt
    49021 gacgggatca tcgaattcag tgcattatca aaagaaaact tgatgacaat cgtcacacta
    49081 atgctagacg atgtcaacca aatgctggca gcacagcaac ttcacatcga agttcctacg
    49141 aatgtcaaag aaaaattagt tgacttaggc tatgatccat ctatgggtgc tcgtcctctt
    49201 cgacgcacga tccaagaaca aatcgaagat ggtatcgctg aattttatct tgatcaccct
    49261 tctatccatg agttgaaagc aaaactggat aaagatggaa aaatcatcgt tacttctaaa
    49321 ccagaacgtt tggctaaaga atcagccgaa gaaacggctg aataaatcca gttttatagc
    49381 gtgagacggt atttctttga gaaatgccgt ctcattcttt tttcagaaaa gtcaaaatac
    49441 tgttcatttt ataaaaaaga aattataata agagaaacaa gcaattaaaa atacataaaa
    49501 gaggtgagcg ccatgaaatt ggtaaatgta acaaacagcc attcccgtct tgtattaaac
    49561 cagcttgaaa acactgatgc ccatctagtc aaggtctaca cagccggaaa taccactatt
    49621 gtctacactg aagcccctga acataatgaa attctgctga tcaatgacaa acgtaaaatc
    49681 cagccgaaag aaatcgaaga tgctaaaaat tatttcttag ataaaatcaa agacgccgtt
    49741 taccacgagg atgaaatcaa agtaatcgaa ttggcaggcc ttgttgaaat ctcgattcca
    49801 aaacatgaat taggcgctac attagccgtg taaacaaatt ttgaacataa taattaaaga
    49861 gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat aaacggcgaa
    49921 agcagaagca actccttcgg aaataagctg aaattcacga aaattgcttt tcaaattttt
    49981 gtgaattcca gcttatttct tggagttaaa cgcttctgtc tcagcctctt tttctttcta
    50041 gctttttgat ttttctcttt tcttttgtac ttttctcttt tcattttcag ttctacgcgt
    50101 gtctttattt ttaacttttt cctctttatg gatgattgat cgtacttttt gtgcaatttg
    50161 ctcgtttttg tcccagtctt ttacatctaa taatcgacat aatcgtaaca tctcttcttt
    50221 tttctgtttt tttctttcac gtctttgcca ttctgtttcc atgtgtcaca ctctcctttc
    50281 tttaatcata tgtacgcaaa ataattttta tatttttttg attagac
//
LOCUS       DAXLPQ010000014        49483 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.014, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000014 DAXLPQ010000000
VERSION     DAXLPQ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.014"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(271..1998)
                     /locus_tag="ACF3UO_001035"
     CDS             complement(271..1998)
                     /locus_tag="ACF3UO_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFD3657079.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(1991..3184)
                     /locus_tag="ACF3UO_001036"
     CDS             complement(1991..3184)
                     /locus_tag="ACF3UO_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3657080.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3371..4015)
                     /locus_tag="ACF3UO_001037"
     CDS             complement(3371..4015)
                     /locus_tag="ACF3UO_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3657081.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4109..4243)
                     /locus_tag="ACF3UO_001038"
     CDS             complement(4109..4243)
                     /locus_tag="ACF3UO_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFD3657082.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4245..6377)
                     /gene="feoB"
                     /locus_tag="ACF3UO_001039"
     CDS             complement(4245..6377)
                     /gene="feoB"
                     /locus_tag="ACF3UO_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFD3657083.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6374..6847)
                     /locus_tag="ACF3UO_001040"
     CDS             complement(6374..6847)
                     /locus_tag="ACF3UO_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFD3657084.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7248..7472
                     /gene="nrdH"
                     /locus_tag="ACF3UO_001041"
     CDS             7248..7472
                     /gene="nrdH"
                     /locus_tag="ACF3UO_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFD3657085.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7631..9790
                     /gene="nrdE"
                     /locus_tag="ACF3UO_001042"
     CDS             7631..9790
                     /gene="nrdE"
                     /locus_tag="ACF3UO_001042"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFD3657086.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            9840..10805
                     /gene="nrdF"
                     /locus_tag="ACF3UO_001043"
     CDS             9840..10805
                     /gene="nrdF"
                     /locus_tag="ACF3UO_001043"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFD3657087.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(10894..12033)
                     /locus_tag="ACF3UO_001044"
     CDS             complement(10894..12033)
                     /locus_tag="ACF3UO_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3657088.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12342..13055)
                     /locus_tag="ACF3UO_001045"
     CDS             complement(12342..13055)
                     /locus_tag="ACF3UO_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFD3657089.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13309..14010)
                     /gene="nagB"
                     /locus_tag="ACF3UO_001046"
     CDS             complement(13309..14010)
                     /gene="nagB"
                     /locus_tag="ACF3UO_001046"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFD3657090.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14244..15776
                     /locus_tag="ACF3UO_001047"
     CDS             14244..15776
                     /locus_tag="ACF3UO_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3657091.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(15967..17169)
                     /locus_tag="ACF3UO_001048"
     CDS             complement(15967..17169)
                     /locus_tag="ACF3UO_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3657092.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17251..17940)
                     /locus_tag="ACF3UO_001049"
     CDS             complement(17251..17940)
                     /locus_tag="ACF3UO_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3657093.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18046..18414)
                     /gene="rplL"
                     /locus_tag="ACF3UO_001050"
     CDS             complement(18046..18414)
                     /gene="rplL"
                     /locus_tag="ACF3UO_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFD3657094.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18467..18970)
                     /gene="rplJ"
                     /locus_tag="ACF3UO_001051"
     CDS             complement(18467..18970)
                     /gene="rplJ"
                     /locus_tag="ACF3UO_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFD3657095.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19174..19301)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(19380..20069)
                     /gene="rplA"
                     /locus_tag="ACF3UO_001052"
     CDS             complement(19380..20069)
                     /gene="rplA"
                     /locus_tag="ACF3UO_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFD3657096.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20173..20595)
                     /gene="rplK"
                     /locus_tag="ACF3UO_001053"
     CDS             complement(20173..20595)
                     /gene="rplK"
                     /locus_tag="ACF3UO_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFD3657097.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            20938..21606
                     /gene="sdaAB"
                     /locus_tag="ACF3UO_001054"
     CDS             20938..21606
                     /gene="sdaAB"
                     /locus_tag="ACF3UO_001054"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFD3657098.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            21619..22491
                     /gene="sdaAA"
                     /locus_tag="ACF3UO_001055"
     CDS             21619..22491
                     /gene="sdaAA"
                     /locus_tag="ACF3UO_001055"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFD3657099.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(22582..23682)
                     /locus_tag="ACF3UO_001056"
                     /pseudo
     CDS             complement(22582..23682)
                     /locus_tag="ACF3UO_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(23774..24661)
                     /locus_tag="ACF3UO_001057"
     CDS             complement(23774..24661)
                     /locus_tag="ACF3UO_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3657100.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(24738..25283)
                     /gene="nusG"
                     /locus_tag="ACF3UO_001058"
     CDS             complement(24738..25283)
                     /gene="nusG"
                     /locus_tag="ACF3UO_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFD3657101.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25384..25554)
                     /gene="secE"
                     /locus_tag="ACF3UO_001059"
     CDS             complement(25384..25554)
                     /gene="secE"
                     /locus_tag="ACF3UO_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFD3657102.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(25578..25730)
                     /gene="rpmG"
                     /locus_tag="ACF3UO_001060"
     CDS             complement(25578..25730)
                     /gene="rpmG"
                     /locus_tag="ACF3UO_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD3657103.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            25892..26536
                     /gene="cbpA"
                     /locus_tag="ACF3UO_001061"
     CDS             25892..26536
                     /gene="cbpA"
                     /locus_tag="ACF3UO_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFD3657104.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(26592..27095)
                     /locus_tag="ACF3UO_001062"
     CDS             complement(26592..27095)
                     /locus_tag="ACF3UO_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFD3657105.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27108..27154)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            27692..28657
                     /locus_tag="ACF3UO_001063"
     CDS             27692..28657
                     /locus_tag="ACF3UO_001063"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3657106.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(28756..29928)
                     /locus_tag="ACF3UO_001064"
     CDS             complement(28756..29928)
                     /locus_tag="ACF3UO_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657107.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(29915..31060)
                     /locus_tag="ACF3UO_001065"
     CDS             complement(29915..31060)
                     /locus_tag="ACF3UO_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657108.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31074..31998)
                     /locus_tag="ACF3UO_001066"
                     /pseudo
     CDS             complement(31074..31998)
                     /locus_tag="ACF3UO_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32115..33194
                     /locus_tag="ACF3UO_001067"
     CDS             32115..33194
                     /locus_tag="ACF3UO_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFD3657109.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33191..33819
                     /locus_tag="ACF3UO_001068"
                     /pseudo
     CDS             33191..33819
                     /locus_tag="ACF3UO_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(33929..34156)
                     /locus_tag="ACF3UO_001069"
     CDS             complement(33929..34156)
                     /locus_tag="ACF3UO_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3657110.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(34259..36847)
                     /locus_tag="ACF3UO_001070"
     CDS             complement(34259..36847)
                     /locus_tag="ACF3UO_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFD3657111.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(36867..37526)
                     /locus_tag="ACF3UO_001071"
     CDS             complement(36867..37526)
                     /locus_tag="ACF3UO_001071"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3657112.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(37575..38078)
                     /gene="trmL"
                     /locus_tag="ACF3UO_001072"
     CDS             complement(37575..38078)
                     /gene="trmL"
                     /locus_tag="ACF3UO_001072"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFD3657113.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(38299..39165)
                     /locus_tag="ACF3UO_001073"
     CDS             complement(38299..39165)
                     /locus_tag="ACF3UO_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFD3657114.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            39274..39915
                     /locus_tag="ACF3UO_001074"
     CDS             39274..39915
                     /locus_tag="ACF3UO_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFD3657115.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(39977..41338)
                     /gene="mgtE"
                     /locus_tag="ACF3UO_001075"
     CDS             complement(39977..41338)
                     /gene="mgtE"
                     /locus_tag="ACF3UO_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFD3657116.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(41356..42255)
                     /locus_tag="ACF3UO_001076"
     CDS             complement(41356..42255)
                     /locus_tag="ACF3UO_001076"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3657117.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(42257..43054)
                     /locus_tag="ACF3UO_001077"
     CDS             complement(42257..43054)
                     /locus_tag="ACF3UO_001077"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFD3657118.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43032..43736)
                     /locus_tag="ACF3UO_001078"
     CDS             complement(43032..43736)
                     /locus_tag="ACF3UO_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFD3657119.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            43867..44442
                     /locus_tag="ACF3UO_001079"
     CDS             43867..44442
                     /locus_tag="ACF3UO_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFD3657120.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            44560..45237
                     /locus_tag="ACF3UO_001080"
     CDS             44560..45237
                     /locus_tag="ACF3UO_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFD3657121.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(45316..47124)
                     /gene="pepF"
                     /locus_tag="ACF3UO_001081"
     CDS             complement(45316..47124)
                     /gene="pepF"
                     /locus_tag="ACF3UO_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFD3657122.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(47300..48298)
                     /locus_tag="ACF3UO_001082"
     CDS             complement(47300..48298)
                     /locus_tag="ACF3UO_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFD3657123.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(48524..49177)
                     /locus_tag="ACF3UO_001083"
     CDS             complement(48524..49177)
                     /locus_tag="ACF3UO_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFD3657124.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        14794 a        10394 c         8723 g        15572 t
ORIGIN      
        1 gtatataaac tatgtatatt ctttaatatt ttttgagaat gcacttcgta cataataaac
       61 tttaatcaca ttagtctttc atacctacga tcgatctctt tgactcgcac ccataaattc
      121 ataatagttt gtcggcgtct ttggacgttt cgaagatgag ctacgcattc tcttttttta
      181 tagacaaaaa agatagagac gaacatggag cttccaaatt tggatatttg atccaatttt
      241 ggaagctcca tttatttcgt gtctgtcttt ttattttttc cagctttcga ctaattcttg
      301 gttctctttg atccagtctt ttgctgcttg ctgtggatct tttccattgt tgatttccaa
      361 cataactttt tccatatctt tttctgacca atggaaattg tctaatactt tgtaagcttc
      421 tggctggtct tctttcaatc cttttcgaac catcgtatgg atctgctctt cgcttcccat
      481 tccgttttca ggatcttcta agtatttcag atcatatttg gcaaacatcc aatgaggtgt
      541 ccatcctgta actacaattg gttcgtgttt tttgatcgct tgacctagtg caacggtcat
      601 tgctcctgaa gaagatgtct ctactttcca gtctttcaag ttgtcatatt tttggatcgt
      661 gttttcagca gccgtaacta caccagctcc tggctcgatt cctatgattt tcttacctgc
      721 ctgatcggtt aactcatcga tcgaatttac atccatgtag gctggcactg ctaaaccaac
      781 ttttgctcct gtcaaattgg cacctaggtc ttcgacttga tctttatatt gtgcatattg
      841 tgaaccatga gttttaggta gccaagctga aaccatggca tctgactcgc catttgaaac
      901 agatttccac atgattgaat tatctaatgg cgtcatcgtt acatcatagc ccatttgttt
      961 caatacttca ccgactacat ttgttgaagc aacttctgta tcccattcaa cataagataa
     1021 gttgatacgt tttgtttctt tggcagatga aaaactccct ataccaatcg cacctaagat
     1081 cactactact acagcaccaa tgatcagtcc ttgacgtttt ttacttttct gtgttgttgc
     1141 tcctgcagct tttttattgt ttggctggtt caaatgctgt gtaaaacggt caatgatgat
     1201 tgctaagata actaatgcaa ccccgttgac aaatccattc ccgacttgtg ctctttgcaa
     1261 tgctgataat acgccgcgtc ctaagccggg tgcaccgatc atagaggcaa taacgaccat
     1321 tgaaagtgac agcattgttg tttgattgat ccctgccatg atcgtacttt tagctaaagg
     1381 caattctagt ttgaatagtt tttgacgact tgtgctcccg aatgaatcag aagcttctac
     1441 taattcttta ggaacttgtc gaatccctaa attcgtaaaa cgaacggttg gtggcagagc
     1501 aaagatgact gaggcaaata cccctggaac catcccgata ccgaaaaatg caactgctgg
     1561 aatcaaataa acgaatcctg gcattgtctg cataaagtca aggatcggtt tgataatact
     1621 ttgggcttta ctgctttttg ccatcaagat ccctaatggt accccaatga tgatcgagat
     1681 cacactagat aaaagaacaa gtgtgacagt attcatcaaa tcattccata gaccttggtt
     1741 ataaataaac catagaccga ttaatgtgaa caacgtaagt cctggacgtt tcttagaaat
     1801 aaagaaagct gctaccgtca ataacaagat aaacaaagga gctggaatca ctaacagtaa
     1861 atttgtaatc cccgacatca ctgcctgtcc aatcgtttgt aaaaatgaaa ataggccaga
     1921 aaaagttgtc gtaaaccatt ctgtgatatt ttctacccag tttgccactg gtaattgata
     1981 gttcaataga ttattcatgt tcactcacct cgcttgtttc tgctaatgct tcaatcacac
     2041 tacctcggat gacgacacct tttaattttc catcctctac aactgcaagt ggagtcggtg
     2101 agtcataaat aatattgaaa atatcactta ccaccatgtc tttcccaatc accgtcacat
     2161 tttcatctag gaagtcgatc aatggacgtt tttgcttcct agcttctaac gcttgatctg
     2221 cagtgatgat ccctttcagg tgtctctttc tgtcaacagc catcagcatg ctgacttctt
     2281 cattacgcat ccttgtcaat gcaacgtttg gtccatcaga ttcgatattc gtcgtcaatg
     2341 caggtaccat gatgttttga gccgtaagca ctttggaacg atcgacttct tccacaaatt
     2401 cacgtacata atcatttgct ggattggtca atatttcttc acctgttccg atctgcatga
     2461 tttcgccgtc tttcatcaag gcgattctgt ccccaatccg taaagcttca ttcaaatcat
     2521 gggtaatgaa aataatcgtt ttttgaacat tggcttgcag gtccagtaat tcgtcttgca
     2581 tttctcgccg gatcagcgga tcaagagccg agaacgcttc gtccatcagc aagatctcag
     2641 gatcatttgc taaagctctg gctaggccaa cccgttgttg catcccacca gataactgac
     2701 taggatattg gtctttaaat gaaagcaaac tagaattttc taatgctttt tctgcttttt
     2761 cttgtcgttc ttctttaggt acaccacgga cttctaaccc gtattctgta ttttccaaga
     2821 tcgttcgatg tggaaacaga ccgaagtttt ggaaaaccat attgatttta tgacgacgga
     2881 cttctcgcaa ttcttctttg cttaacttcg atacatcttc tccatcaata tagatactgc
     2941 ccgaagttgg ctcaatcaga cgattcaata gacggatcaa tgtggatttc ccactcccgg
     3001 aaagccccat gatcacgaag atttctcctt cttttacgtc aaaattcacg tcatacacac
     3061 caaccgttgc accggttttc tttaaaatct ccgttttcgg ctggtgatca ttcatcatat
     3121 ctaaagcggc ttgtgtcttt ttaccaaata tctttgttaa atgttttact tctactttta
     3181 ccaaacaaat tctccttttt tatgtaaatt catttttctt tctgaaaaaa gtgaccacac
     3241 tatgttaaca tcatgtagtc actttgtcaa aaatgaaaga aatttgcttg tccaaactga
     3301 aaaaaacttg gctaaatctt tgtaaataaa aggtttagcc aagttaatat ttttttaata
     3361 tttcacacaa tcattctgca agctgatgct ccgggtaaaa aaagtttgtc atacgctgta
     3421 gtgtatattc atttccaata aaatgaacga tgtcccctgc cgtaaattta gcataggggc
     3481 caggtgaaac aagcagttct tcattatgag aaattgcgat aactgtggcg ccagtcgcct
     3541 gccagatatt caactcgcta attgaacggt ccagatgcat tgctttttct gataaagata
     3601 attcaaacgg aagtaaagga ttcatcttat gtattcgctt cgtttgattg accagctgat
     3661 ccaataattg agaaaaatga ttcagctcat cttgttgctt ctccacactt gccatgattt
     3721 ctgcttttgt atcttggatg gattgtacat cttgatattg caataggaaa tcttttgctt
     3781 tttccttcga agcaacaaat gccccacttc catgccgtac ttccatgatt ccaagatcta
     3841 ccagcacatt gatagccttg cgggtagtct caggagaagc attgtacgta ctggcaagtg
     3901 ttgagcgggc atggatcttc tcacccactt tatatcggtt ttcaacgata cgttcggcta
     3961 aatcaacagc aatctgctgg tagcgcgggc ggacgatttt tttctttcca gacattttct
     4021 ttcctctttc tttttttact ttccctcatc ttactatgct ctagcaaaat aagcaaaaaa
     4081 ggggagaata gcctcttgca acgactgatc atcgcttgat ctgttccttt tttactgggc
     4141 aagctgtttg acagtcatca caattcttac cggattttaa acgagtatag acaattgcgc
     4201 ctgcacttcc aaagattaac acacttaata agaatgtcgc catcctattc ctctccttct
     4261 aatgacaata tagtataaaa ctggttcttg gattttggct gacggaacaa aacataaacg
     4321 agtcctatca tcagtaaaat agcaagatac gtccctaacg ctacctgtcc accctccaat
     4381 aagtgtccca actgataaat cacaaaacta actaaataag ctaaaccgca ttgatagcct
     4441 atggcgatcc aagtccattt cttggcattc atttcccgat ggatagcccc aattgccgca
     4501 aaacaaggcg cacaaagtaa attgaaggct aacaatgaat aagctgctgc gggagtatat
     4561 gtgtgttgta gcacttgcca gatttctctg ccattttcgg atacttccgc atgaccaaac
     4621 aaaataccaa atgtgccaat aatattttct ttagcgacca atcctgtaat cgctgcgact
     4681 gttccttgcc agtttcccca accaagcggc tgaaaaacaa ctgccaggat tcgcccgaaa
     4741 aaggctaaga tactttggtc ttcagaaaca ggttgagcat aaaaattata agaagagctg
     4801 aaccagatca cgatactaga aacaaagata atcgttcctg cttttttaac aaaagacttg
     4861 ctgcggtcat aggtttgtct taggaccgct gaccattgag gaaaatgata tgcgggcaat
     4921 tccatgataa aaggagctgt atctccagca aacaaacgtg tttttttcaa gctgattcca
     4981 gagaaaataa ttgcagtcat accaagaaaa taggcagaag gagctaccca agattgatga
     5041 ggaaaaaagg cccctgctac taaggcaata atcggcaact ttgcagaaca aggcatgaag
     5101 gttgtgacca tgatcgtcaa acgacgatct tgctcgtttt caatcgtgcg actggccatg
     5161 acgcctggca ctccacatcc tgtagcaatc agcataggaa tgaaggattt tcctgaaaga
     5221 ccgaatttcc tgaaaagtcg atccatgaca aaagcgatcc tcgccatata tccgcagtct
     5281 tccagaaagc tcaagcataa aaacaatata atcaattgcg gtagaaatcc taacactgct
     5341 cccacgcctg cgatgatgcc gttcaagatc agctcctgca tccatcccgc tacttgccat
     5401 tcagctaaca atctgccaac atgttctggt aaccatgtac caaacaatgt gtcattgatc
     5461 caatctgtcc ccattgttcc tactgtttga atagccagat aatagatcag ccacatcaca
     5521 aatgcgaaga tcggcaaggc taaccaacga ttcgttgcaa tctgatcgat tttgtcactc
     5581 atcgataatt ggaaagaatc atttgacaca acacagagtg tacatagttg ggtaataaat
     5641 tcataacgtt cattgaccag aatcgtctca ctatcgtcgt ccaatagttt ctctgttaac
     5701 tggatcagtt gctcgatctc tttttgctga gaaactgcta tctcgtaatc ctctcttacc
     5761 ttctgatctc gttcaaaata tttcattgca taccagcgtt tcttgccgct ttgttctcct
     5821 agtacatctt caatttcatg taaagctgct tctaaacgtg gatcatatgt acagggaaca
     5881 ggaatagaag gccgcttttt tgcagactcc tgaatctttt cgattagttt ttcgattcct
     5941 tgctttttca atacgctgat tggtaaaact ggtacaccaa gaccatagga aagcttttct
     6001 agattgattt tttttccttc ttttttgatg acatccatca tattcagacc aatgatcata
     6061 ggaatgtcta aatccaataa ctgcgtagtt aaataaagat ttcgttctaa attggtagca
     6121 tcaataatgt tgatgatcag ttcaggctgt tcctgaacca aataatctct tgcaatcact
     6181 tcttctggtg tataaggaga caaagaatag atgccgggta ggtcctgaat atgaatgttc
     6241 ggattttttt tcaacgatcc ttcttttttt tctactgtta cgcccggcca attccctaca
     6301 tattgattcg aaccagtcaa gagattgaac aagctagttt tcccgctgtt tggatttccg
     6361 actaacgcga tattcattct ttttcctccc tttgtatcaa gattagttcg gcctctgact
     6421 ttcgtaacgt cagttcatac cctcgcactg tcagttcgat tggatctccc agaggggcta
     6481 gttttcggat aactattttt acatttcgcg tcaatcccat atccattaac cgtcgcttca
     6541 ctgcgccttg tccgtggatt gctacgacga tcccagtctc tcctgctttt aattgatcaa
     6601 gagaagtcca gctttcagag gaagcagtct ttttattgac aaagatttga cctagtattt
     6661 cccgacttac tgccactcga tgacttttta ccagtaaaat ggcattgttg cctgataaat
     6721 tgacgacgac gattttactt ccggcaacga tcccgatatt ttgcaaatgg cgttttgttt
     6781 tttcttctgt ttcgattcgt tcgacttgat aaacgaaatt ctgctttgcc tgcgctaagg
     6841 tctgcatatt gattcctctc ttgtgaaata aatcatgtat taaaatcatt cattatatgt
     6901 tctaattttc ttacgtgtta cgcaaataaa tgagaatcat tctcacatag aatactctcg
     6961 gtaattgaga atgtcaatta tacttgtgat attatgagcg aatctttagt attgatagat
     7021 aaaaatgaga aaaaaatatt tcttcatagt tttccacaat tttttctcta ttaaatttgc
     7081 tattttccca cacgatactt gttttcagct cttttttcaa aaacacaaaa cttagtattc
     7141 cacagtttcc acaacacaat atgtagtgtt tgttgtttga cttttttact aagagtttta
     7201 tactatctat tatagataat aagaatgtgt tagaggaggc actcaccatg aacgtaaaaa
     7261 tcttttctaa aaataattgt atgcaatgta agatggtcaa acggttttta acagaaaatc
     7321 aaattgcttt tgaagaagtc aatatcgatg aacagcctga agcagtagac tggttgaaag
     7381 cacaaggatt ccaaagtgtt cctgtcatta cttctgatgc agaaacagtt atcggattcc
     7441 gtcctgatca gttgcgtaaa cttgccagct aacatgacta aaagaatcaa aacgtgatac
     7501 atggatttga agggcttgag acagcaccag tttttgtcgc aaacttccaa atcctttttt
     7561 aaagcttaaa aacaatgcaa tgatttgcaa tcaagcatca tcaaatacga aatgaaggtt
     7621 gggcgtacgt atgagtctta aaaatttaca agatgtcagt tatttcaagc tgaataatga
     7681 aatcaatcgg ccagtcaatg gtcaaatccc tttgaataag gataaagaag ctttagttgc
     7741 cttttttgag gaaaatgtca aaccaaatac gatgactttt ctatctatta tggaaaaaat
     7801 caattacttg atcgatcaag aatatataga agcagaattc attcaattgt attcaccatc
     7861 atttattgaa aagctatatc aatttttgga cgagcaacat ttttctttca aatcttttat
     7921 ggctgcttac aaattttatt ctcaatatgc gttgaaaacc aacgacggtt ccgcttatct
     7981 ggaaacttat gaagatcgag tagccttcaa tgcgctttac tttgcgaacg gggatgaaga
     8041 attagcactt gctcttgcag acgaaatgat ccatcaacga tatcagccag ctacaccttc
     8101 tttcttgaat gctggacgta aacgtcgggg cgaattggtg tcttgtttct tgactcaagt
     8161 cactgacgat atgaactcta tcgggcgctc aatcaactct gctttgcaat tgtcccgtat
     8221 tggtggcggc gtagggatta ctttatcaaa tcttcgtgaa gccggcgctc ctatcaaagg
     8281 atatgagggt gctgcaagtg gtgtcgttcc agtcatgaaa ttattcgaag atagtttcag
     8341 ctattctaat caattaggtc agcgtcaagg agctggcgtg gtttatttga acgttttcca
     8401 tccagacatt attgctttcc tttcagcaaa aaaagaaaat gcagatgaaa agattcgcgt
     8461 aaaaactctt tctcttggcg tgatcgtacc tgataaattt tatgaattga cacgtaaaaa
     8521 cgaagatatg tatttattta gtccatatag tgtcgaaaaa gaatatggtg tcccattctc
     8581 ttatgtaaat attacagctg agtatgatca tctagttgca aatccaaaca ttcgcaaaca
     8641 aaaaatcaaa gcgcgtgatc ttgaaaatga aatctcaaaa ttacaacaag aatctggcta
     8701 tccttacgta atcaatattg atacagcgaa ccgcgagaat ccaatcgatg gcaagatcat
     8761 catgagtaat ttatgttcag agattttaca agttcaaacg ccttctgtga ttaacggcaa
     8821 acaggaatat gaagtattag gaacggatat ctcatgtaac ttaggctcga caaatatcgt
     8881 gaatttgatg caaagcccta actttggtca atctgtgcgt acgatgactc gtgcattgac
     8941 atttattaca gatgcatctg atatcgatgt cgtaccaccg atccaaaacg gaaataagct
     9001 gaatcatacg attggattag gtgccatggg cttacacact tatcttgcaa aagaacaaat
     9061 ggaatatggc tcagaggatt cattagactt tacaaatatt tacttcatgc tgttgaatta
     9121 ttggacactt gttgaaagca acaatatcgc tcgtgaaaga aaacaagttt tccataattt
     9181 tgaaaaatca gcttatgctg acggcactta tttcgaaaaa tacgtaactg gagaattcca
     9241 gccaaaatca gaaaaagtca aagcattgtt tgaaggcatt tttatcccaa ctgctgaaga
     9301 ttggaatgct ttgaaacaag cagtaatgaa agatggactg tatcatcaaa atcgcttggc
     9361 agtagcacca aatggctcaa tttcatatat caacgatacg agtgcaagta ttcatcctat
     9421 cactcgcatg atcgaagaac gccaagagaa gaaaatcggt aaaatttatt acccagcgcc
     9481 ttatctatcc aatgagacga ttccgtatta cacttctgct tatgatatgg acatgcgtaa
     9541 agtaatcgat gtttatgcaa tggcacaaca acacgtcgat caaggcatga gtttgacttt
     9601 attcatgcgt tctgaaatcc cagaaggcat ttatgaatgg aagacaacaa cgaagcaaac
     9661 gacacgtgat ttgaatattt taagacatta cgctttccac aaaggaatca aatccattta
     9721 ttacgtacgt acctttactg atgatgcaga agaaatcgga agcaatcaat gtgaaagctg
     9781 cgtgatctaa tatcatagat agattcgctt attcatattt taattaaagg agcattctca
     9841 tgtcagaaac atattatgaa gcaataaact ggaatgaaat tgaagatatc attgataaat
     9901 ccacttggga gaagctgaca gagcaatttt ggctagatac acgtatccca ctttcaaatg
     9961 acctagatga ttggcgtaca ttgtctcaat tggaaaaaga tacagtagga catgtatttg
    10021 gcggtttgac actgctagat actgtccaat ctgaaagtgg catggatcag ttgcgtaaag
    10081 atgtccgcac tccccatgaa gaagccgttt tgaacaatat tcaattcatg gaatccgttc
    10141 atgccaaaag ttattcttct atttttagta cactgaatac gaaaaaagaa atcgaagaaa
    10201 tttttgactg gacaaatacg aatccttatc tgcaaaaaaa agctgagcgt atcaatgaaa
    10261 tctacaaaca cggtacaccg ctagaaaaga aaattgccag cgtcttttta gaaacattct
    10321 tgttctattc aggtttttat actcctcttt attatttagg aaacaacaaa ttggctaacg
    10381 tagcagagat catcaaacta atcatccgag atgaatctgt acatggaacc tacatcggtt
    10441 acaaattcca attaggattc aacgagttac ctgaagcaga acaagaaacg ttaaaagact
    10501 ggatgtacaa tcttctttat gagctttacg aaaacgaaga acgttataca gaagaattat
    10561 acgatccaat cggctggaca gaagaagtca agacattcct acgctataat gccaacaaag
    10621 cattgatgaa cctagggatg gatccactct ttccagatac tgccaatgat gtcaacccaa
    10681 tcgtaatgaa cgggatttca acaggcacaa gcaaccatga cttcttctca caagtcggaa
    10741 acggctattt gttaggtcat gtagaagcga tgaaagacga cgattatttg attggattgg
    10801 aataaggatt tattttaatt caaaaatttt tcgaaaaata aaaagagttt agcgtacaga
    10861 tattttaaat gtacactgaa ctctttttta tgcttattca cttgtttctt ccagcacttt
    10921 tggactgtct aacttttccg aaacatgttc cattcttctc aataaataga ttttccggat
    10981 atttaatatt atcgtcttaa tcactgcata gacaggtatg caaatcagca tgcctaatat
    11041 tcctgcgaca cttcctgctc caatcaatac caagatgatc gtcaaaggat ggatattcat
    11101 tgatttccca aataacaacg gcttgatcaa atttccatct aattgttgga tcactaaaat
    11161 cgacaacgcc atatacaaag cttgaaatgg agagataaac aaaccgacaa tgattgctgg
    11221 taccgctcca ataaaagggc cgacatacgg gataatattc gtgattccgc aaatgaccgc
    11281 aagcaacaag ctataaggct gatcgaatat tctcattgcc aaaaagctca ttacaccaat
    11341 aatcaaagca tctaagatcg tactgctgat ataggcagat aatgtttcgt ttaattcttt
    11401 taccgtttgg cgtaactctt tacgaatcgc tttcggaaag aagtgagaca acgcatcaat
    11461 aaatttgtgc ccatccttga acataaatag caaaataaat ggaacggtaa ataacaaaat
    11521 aaaaaattgc atcataaatg aaatgatttt tgagacactt gcagataaac tgactaatat
    11581 gatattgaac aaattactaa gagataaatt tgctgatgct aattgttctt ccaaattgaa
    11641 atttttaaac tcttcccgct gcgccaattc atttaaccat ttgcttgttt catctgcata
    11701 cattggcaag ctctgggtca attgaattgt ctgttccatt aactgaggca ctacattcat
    11761 gacagttaaa acaactaaaa tgattacgac caaaaacgtc aataaaaaac cgaacactct
    11821 cgggatccga tgcttttcga gaaaaacaac gattggatcg aacatataat agataaaacc
    11881 agcaacaagc aatggtaaaa aaactgccga aagcattttc aatattggac taaaaatatt
    11941 cggcatttgt aaaataaagt acacgccgat gatcgtgagt actagctcca ctgtccagaa
    12001 aaataatttt gattgtttaa aacgtgattg catacatctc ctccaaggtc ctttgatact
    12061 tctattctat catttaacaa agagttacgc gctgagattt tcatttgctt aaaaaaaaca
    12121 aaaaaaataa acatatttta atgagtagac gagtacttaa acaaaaacac ggtttggagt
    12181 agtgacaaaa attatactgc agtccctttt tccaaataaa cggtgttcaa aagcttgcat
    12241 cttcgtaata agcccagcca aacgaaaaat ataaggaact atttttattt ggctgggctt
    12301 attacttgat gtaggacatc tattttacaa cctcagatca tttattgcgc aatactgact
    12361 aaatgcaact ttgtgatatt tttgtgtacg gacaactcct cgatcacatc ggcataagtg
    12421 agcccttttg gaagatcaat cgtatagata tttttgtaca ctcggtagtc atcaacgaat
    12481 tttacgtcaa aattcacatc ttcgattacg atatttttct cttcaaaata atcggtaaga
    12541 aaatctttgg tttcttttct atggataaat tggatttcta actttttagt cgtaggtaca
    12601 tggatcacgc gtttcactac tgtgagtgca atagcaatcc cgataaaact gatgatcgca
    12661 atggaatagt aacccatgcc gatggcgatc cctaatccag caattgccca taaagaagcg
    12721 gcagtcgtaa gtcccgtcac cgattgtttc gtgacgatga tcgttcccgc gcctaagaaa
    12781 ccgacaccac tcaccacttg agcaatcagc cttgcttcat ctgaacgaat cgttccagca
    12841 agctgtggat actctaaagc atctcttaat gcaccactag cgatctcaac ttggatcaat
    12901 gcaatgatac atgctcccat acaaactaaa atatgcgtac gcatacctgc tggacgattt
    12961 ttatattgtc gttcaaaacc gattgctccg ccaaatagca tagcgatccc taaacgtaaa
    13021 ataatctctg gaattgtcaa taccatatca ttcatctaaa caccctccag tccaatatat
    13081 catgtctgaa aggagcagac aaaaaaagtg caatttttac ctcttacgaa aaaaggactg
    13141 tgacaaaatt tttgtcatag tcctttttat gaataaacgg tgttcaatca gctgaccctc
    13201 ggtattactc aacaaacggc aaaatatggg gagctatttt tcctttgtct tctctaatac
    13261 tcaggtcaaa acgctgattt cacaacctct ttagcctact attgaaaatt acaacttact
    13321 tgctgcttct tcatcgatga tcacaacaac attgtcgtga ttttgcaata cacttgctgg
    13381 caaatgattc gttacaggtc cttcaatcat ccctttgatt gcatcagctt tgctttcgcc
    13441 aaatgccatc aagacgattt ctttactttt cataattgaa ccgattccca ttgaaacagc
    13501 ttttgttggt acatcttctg ctttatcgaa gaatcgtttg tttgcattga ttgttgattc
    13561 tgttaagtca actactgaag tcgttccgtc aaatgaagca ccaggttcat tgaaaccgat
    13621 atgtccattt tgcccgattc ctaagatttg gatatcgatt ggatgtgcat cgatgatttg
    13681 atcatacttt ttgcatgctg cttccagatc ttctgctttt ccatctggta caaacgtttc
    13741 tttgaatggt tttttatcaa ataattggac atccatgaaa tgacggtagc tttgttcatc
    13801 tgaaccgcct agtccaacgt actcatctaa gtttacagaa gtcatttcac tgaaatccaa
    13861 atcgcttgaa gtcatttctt tatataaagt aactggtgtg cttcctgttg ccaatcctaa
    13921 tacttttgca cctttgttca taccttcttt gatgatttca aatgcttttt ttccgccttc
    13981 ttcagcgttt tttacacgaa tgatttccat agtgattgct cctttatatt ttggtatagc
    14041 ccaattatag cattcttttt ttctttttac aataattagt atagaccaaa ttgcattttt
    14101 ttcattttct tgacaataaa taggaatccg tgttaggttt cataagatgg ttcaatcaaa
    14161 caatccatgt tgcatgaaaa ccaagcaagt gattcactgt ggacgcttta tgtctgcagt
    14221 ttttttatga aaaaggagtt attatgagta tactgacatt aaacaacatt acccagcaat
    14281 ttggcgacaa aatcctctat gaaggtgtcg atctgcaatt aaatgctggc gaacatcttg
    14341 ggctgattgg acaaaacgga gccggtaaaa gtacattgat taaaatcatc actggtgaga
    14401 tcttaccaga tgacggacag atccattggc aaaaaaatat tcacaaaggt tacctcgatc
    14461 aatatgtgga agtcgatgaa acattaacaa tcgaagaatt tctaaaaact gcgtacgcaa
    14521 aagaatacga aaaggaagaa aaaattgctt ttctttacca aacatatagc gagaccttcg
    14581 atgattcctt gctggaaaaa gctgggaaac tccaaacgga attagaccaa ggagtgtttt
    14641 atcaaatcga caccttagtt gctgagatga gcagcgggtt ggggatcgat gtcttaggtt
    14701 tagattcact gttgaaaaat ctaagtggtg gacaacgttc aaaggtgatt ttagcaaaac
    14761 tacttttaga aaacccagat gttctgatct tagatgaacc aaccaatcac ttagatgatc
    14821 agcatatcca atggctgacg cagtttcttc aggattttga cggtgcgtat atcgtgattt
    14881 cccatgacca agaatttctt gatcagatca ccacccatat cgcagacatc gagtttggaa
    14941 agattactaa gtatactggc catctaaaac aagcattgaa acaaaaggaa caaaatcgcg
    15001 aaagctattt gcgccaatat catgctcaac aaaaacaaat cgaaaagacc gaagcttata
    15061 ttcgaaaata caaagccggt tcccgatcaa cgatggcaaa aagccgacaa aaacaattag
    15121 ataaaatcga acggctgacg cctccagctt cagcaagtaa agctgtcttt gattttccat
    15181 tctcgcctat tgtcacgaca ttagcagtgg aaacaactga tttagtcatc ggatatgatc
    15241 gaccgctact tgcacccatc aatttgacca tccgctttgg tgaaaatatt gccattcgag
    15301 gcttcaacgg gattggaaaa tctactttat taaaaacact gatcggtgag attgaaaaaa
    15361 taagtggcga tttccacttc ccagataaca caaaaatcaa ttacttttca caagatctgt
    15421 actgggaaaa tccattagaa acaccactac aatatttaag cagtcaattt ccaaaagcga
    15481 ctatcaaaga attacgtcgc caactagcta aagcagggtt agttaatcaa ttagcaagtg
    15541 aacctctcac tacattaagt ggtggggaac aaactaaggt gaaacttgca cagttgacaa
    15601 tgaaccaagg taatttactg attctcgatg aaccgacgaa ccatatcgat caagaaacga
    15661 aagaaagctt acaagacggg atacagaaat ttccaggaac agtaatcatc gtctctcatg
    15721 aacaagaatt ttatcaagat cttgtgcaac gagtcattga gattgaacca aaataaacgt
    15781 ttgattgaat agttgaaaaa aaggagctgt gacaaaagtt ttgtcacaac tccttcttct
    15841 gaataaatgg tggccaatta gctgaccttc ggtattagct caaaaaacgg caaaatatga
    15901 ggagctattt ttatttggct attcttatta cttgatgcag aacagctttt cacaacctct
    15961 tttcgtctat tttttatttt cgagatttct ctttccttta aaaacaactg tttgaaagaa
    16021 gaacgcacat ccttgaaaaa caagcccgct aaccgttaca cctaaccagc catactgctg
    16081 ccacattgtc gtccctagca atgaaccagc cgcacctcca ataaagtaca taaacataaa
    16141 tacagtatta tttcggttgc ttgctgcttc acctagccct tgtactcgtg tttgattggc
    16201 gacttgacca aattgattcc cgacgtctaa taaaataata gctaaaagca aaatggccaa
    16261 atggcttccg ccaaccaata aagcaataaa gcttattgtt tgcataacaa gtcccatata
    16321 cacgattttt ctttcagaat aagaatctgc cagtcgtccc acgataggtg cagcaactgc
    16381 tccagacaaa ccaaaaatcg ctaatatccc tgcttcgaat gttccccaat tgtaggcggg
    16441 actgctgata taaaaaatca acgtagacca aaagatcgaa aatgttccaa acatgaaaaa
    16501 tccactgact gccgcttctc ttaatagacg ttgagaagca actaaatgcg gcaaactttt
    16561 aagtgaatca aggtatgaaa cagctgtact actttgctgg acagaacgcg gcattttcca
    16621 gtaaagcaga agtgtaagaa ttccgactgc acataaagca aataaataga tcatccgcca
    16681 agaaaaaaga ctggcaacaa taccagatac cgtccgagaa agcaaaatcc ccacgagtaa
    16741 accgctaagc aatgtaccca tgaccttccc tcttgctttt ggtcccgcta gtaccgcacc
    16801 gtaaggaatg atgatttgcg gcacgatcga aagtaatcct attaaaaaag aagcgcatgc
    16861 aaataacgta aacgaaggcg caaaaaaagc ggccaacaga gagacggcag ataacgctgc
    16921 cattcgaatg atcaattttg gacgatccac cacgtcccct aaaggaacta aaaacagtaa
    16981 ccctaacgca tagcctaatt gggtcaacat cgtcaatatc ccgactgcac ttgtgctaac
    17041 agataaacta gctgctactt ttgttccaat cggctggatg taatacatat tggcaacaac
    17101 aacgccacaa gtgattgata atagtaaaat aagcgaagtt gttaaaggtt ttttttcatt
    17161 actcttcatt gatttccccc atttcctatc ttagtttaca acttatggaa aagattggaa
    17221 atagaaaaat acaactattc gccacactta ttatttgtgc ttttgttttc cttgtttttt
    17281 cttgcgatct ttataaatga agacaactaa ccctactagc acagtaacac ttgcaaccaa
    17341 cgtgactgca gttttgttat atccgtgaaa cagagcttct ccaccacacg catacaacac
    17401 agacgaaggg atgactccaa tcacgatcga caatatgatt tgctgtagag gcaatttcat
    17461 cgcatctgca gcaaaattga ccatagaaga tggaataacc ggtatcatat agcctaacat
    17521 tacacctatt tttggatgtt tcatttgtcg gattgcttgc acccaatgat tcgtttcggt
    17581 tttcttatct aaaaatttta agcgatgcat aaggaaaatt gcagtgatgt taccaagagc
    17641 attacccaaa atgttgatga tcgcacctgt cagtggtcca aagctcaaac cagcaatgac
    17701 tccaactact gaagtaggaa tacctggaac agcacacatc accgctgtca atacgatcaa
    17761 gagtatcgat gcaaaagtcc catgcgaacg aatatgtgcg agtagctctg ccttactcgc
    17821 tctcggattt aaaaataatt ggatgtctgt ctgatattct aaatacaacc gatagcccac
    17881 taccagtatc agaatgattc ccaacgagat caatatcaat cggattattt tctttttcat
    17941 atttcctcct gaaaaaaatc tatattcatt aaataatagt ttaacataaa aacaaaaaag
    18001 caccgaaatc caacatagga tctcagtgct tttaaatagt aaaaattatt taacagttac
    18061 agatgcgcca acttcttcaa gtttagcttt caattcttca gcttcttctt tagatacgcc
    18121 ttctttaact ggtgcaggag cgccatcaac tacagcttta gcttctttca agcctaaacc
    18181 agttgcttca cgaactgctt tgataacttt aactttttgg tctccagctg cagttaattc
    18241 tacagtgaat tctgtttgtt cttcagcagc agcagcgcca ccagcagcag ctacagctac
    18301 aggagcagca gcagatacgc caaattcttc ttcaatagct ttaactaggt cgttaagttc
    18361 taggatagtt gcttctttta actcagcaac gatgttttca atgttcaatg ccattataat
    18421 ttcctccgtt taattgttct tttttattta atgctttatg cggcaattaa gctgcatctc
    18481 catcttcttt gtctgccact gctttgacag cgtaagccac gttgcggact ggcgcttgta
    18541 gtacagatag caacatagat agaagtcctt cgcgatttgg caattttgcc aatgctgtga
    18601 tttcttccaa tgaagagact ttaccttcga tgataccgcc tttgatttct aatgcttttg
    18661 cttctttagc aaattcgtcc atgattttcg ctggtgcgac tacatcttcg ttactgaatg
    18721 caacagctgt aggtccagtg aatacttcgt ccatgccttc aaggccagct tttttagctg
    18781 cacgtgaaag aatagaattt ttgataactt tcatttctac gttagcatca cgaagttgtt
    18841 tacgtaaacg tgttacttca tcaactgtta atccgcggta gtcaacgact actactgatg
    18901 cagctgctgt aaatttttcg cttacttcat caacgattgc tgcttttttt gcgataattg
    18961 cttcactcat ttttgagttt cacctcctga attttgatgg aagagttttt tgcactgaaa
    19021 aggcaagtca cttttatagt tactttgctc aaccagtatt attcatcacc tattcacttc
    19081 gttcatagtg attctactcg ctttgctcga aaggaaactc ctttcgcttt gctcaaccag
    19141 tattgttcat catctcttca cttcgttcat agtgattcac aataaaaaac tctatgccac
    19201 cgcagacata gagggactat tgaatatatt caataaacgt cctcggtagg aaattaaggc
    19261 ttgatgccac ctactgtctt cggtacaagt taattattaa cctcaactag cttagcatgc
    19321 taaactagtt gagtcaagaa ttatttttca gttggatcaa tcaacattct aatatttaat
    19381 tagaaagaag cttggtcaac atggatacca ggtccaaatg ttgttgtgat cgttacattt
    19441 ttcatgtatt gacctttagc tgctgatggt ttagctttta gcaatacatc atggattgct
    19501 gcaaagtttt caactaattt ttcatcgtca aatgaaactt ttccgattgg tacatggata
    19561 tttccagctt tgtccacacg gtaagttact ttaccagctt tcacttcgtt tactgctttt
    19621 gttacgtcca ttgtaactgt accagtttta gggtttggca ttaagccttt tggtcctaat
    19681 actcgtccta gacgacctac agtagccatc atatcaggtg ttgcaacaac tacatcaaag
    19741 tcaaaccatc cgttttggat tttttgaacc atgtcgtcgt cacctacgaa atctgcacca
    19801 gctgcttcag cttcttttgc tttgtctcct ttagcaaaaa ctaaaacagt ttgtgtttta
    19861 ccagttccgt ttggtaatac aacagcacca cggatttgtt ggtctgcttt tttagggtct
    19921 acgttcaaac ggtatgcaac ttcaactgtt gcatcaaatt ttgcaatgtt tgtttctttt
    19981 gctaaagcta ctgcttcggc aacaggataa actttacttg aatcaacttt ttttaatgca
    20041 tcttgcattt ttttgctctt tttagccatt ttggttcctc cttgattgtg gttataacgg
    20101 ttgtacctcc cacgtgttct atatctttca atatagagcc aactgagaag ctgctgtctt
    20161 agggtgtata gattattcta cagtgatccc catgcttcgt gcagttcctt caaccatgcg
    20221 cattgctgct tcaacgttag ctgcgtttag gtcttccatt tttaattcag cgatttctct
    20281 tacttgatcg ctagaaactt tcgcaacttt atttttgttt ggttcgcctg aacctttttc
    20341 gattttagct gcttttttca atagaacagc agctggcggt gtttttgtaa cgaatgtgaa
    20401 tgaacggtct tcgtatacag aaataacaac cggaatgatc aaacctgctt gatcagctgt
    20461 acgagcgttg aattcttttg tgaatcccat gatattgata cccgcttgac ctagtgcagg
    20521 acctactggt ggagctggag ttgctttacc tgcaggaatt tgcaatttaa cgattttttc
    20581 tactttcttt gccacgagac atacctcctt aagtccgtga tgtggttaat tggagatgca
    20641 tatttctcct cccacgtttt atctgatctg aaaaaatcca gacaaataat gtgcaaaaca
    20701 atgcacactg gtacagtata gcaaatttat ttgttttttc aagatttttt tctgctattt
    20761 ttacattttg cttgaataaa cgctaaattt attctaaaaa aacaacaatt tttcgttctc
    20821 atttcttctt ttatgttaca cttgcgctag catggttcaa cagatgaaag caaacaataa
    20881 cacggttttt tagacccttg tacaaagatt cctacataac aaaatgaggt ggagaaaatg
    20941 aaagatttaa ggtatagaag tgtctttgat attattggac ctgtgatgat tggtccaagt
    21001 agctctcaca ctgccggagc tgctagaatc gggaaaatca tacgtagtat atttggcgaa
    21061 cagcctgatt ctgtagatat ttatctatat gaatcatttg caaaaaccta tcgggggcac
    21121 ggaacagata ttgcattagt tggcggcctg ttagggatgg aacccgatga tgaacgttta
    21181 gctgattctt tgaaattggc atatgaagcc ggtatggaag tcttgtttgt tcctaagagt
    21241 gaaaaagccg aacatccaaa ctctgtaaag atgcttctaa aaaaaggaac acgaaagctt
    21301 tcagtcactg gcatttcgat cggcggtggc aatatccaga tttctgaatt gaatggattc
    21361 aaaatttctt taagcatggg tactcctacc ttgatcgttg tccaccaaga tgttccaggt
    21421 atgattgcta aagtgactag tatactttct gagaccaata cgaatatcgg cactatgaca
    21481 gtgacacggg aatcaaaagg tgaaaatgcc attatgataa ttgaagtaga tgatcctcaa
    21541 gtagaagaaa cggtaaaaag actcaaacag ctgccaaata tcgacagcgt aaattatttc
    21601 gattaaggag ctaaaaaaat gtttttatcg attgaagaat tagtagatca agcaaaagct
    21661 tatccaagtg tagcagaatt gatgattgca gttgaaatgg aaatgagtgg ccgttcccgt
    21721 agtcacatca tcgagatcat ggaaaaaaac ctctcagtaa tggaacaatc aatcaacgag
    21781 ggaaaagaag gtgttacctc cgtcacagga attaccggtg gtgatgcaaa aaaattagat
    21841 gattatttaa atgaggcaga ctttttaagt ggagaaacaa tcttaaaagc tgtacgcaat
    21901 gctgtagctg ttaatgaagt caatgcaaaa atggggttga tttgtgctac accgactgcc
    21961 ggaagcgcgg gtgttgttcc tggtgtgctg atggctgtcc gagatcggct tgatttgaca
    22021 catgaacagc aattggaatt cttatttacc gctggcgctt tcgggttagt catcgcaaac
    22081 aacgcttcta tcagtggtgc agaaggggga tgtcaagcag aagttggttc tgcaagtgca
    22141 atggcagcag cagctttggt ttgtgcaaaa aatgggactc ctcatcaagc agcacaagca
    22201 gtagccatta cattgaaaaa tatgatggga ctgatttgcg atcccgttgc aggcttagtt
    22261 gaagtcccgt gtgtcaaacg taatgcttta ggctcttctc aagcttttat ctctgctgat
    22321 atggcattag cgggtatcga aagtgtcatt ccgccggatg aagtcgttgc tgcaatgtac
    22381 caagtcggac gtcaaatgcc gtcgattttc aaagaaacag cagaaggtgg cttagctgtt
    22441 acgccaactg ctaaacgact tgcggaagag attttaaata agagggcgtg ataaagctcc
    22501 ttaatttcga gtattaagag attagttatc ttcataacaa aaaacgaaga gaggactaat
    22561 tgcccttctc ttcgtttttt attaatccat caatttcgta ttttttactt catcgatcgt
    22621 ttttgttcct gcaagttgca tcgtgatcga caattctttg ttcaggtgtt caaaaacaga
    22681 tgttactcct tctgccccac ctagattcaa cccataaatc actggtcggc caatcgcaac
    22741 taagtcagca ccacttgcca gagctttgaa gacatgctct cctcgacgga caccagagtc
    22801 gaaaatcact ggtacacgtt tgttgactac ttcggcaatt tttggcaata cttcaaagga
    22861 cgcaggacct ccatctagtt gacgtccacc atgattggat acccagatac catctgcccc
    22921 tgcagagata gcgattactg catcttctgg cgattgtatt ccttttacga taactggaag
    22981 atgggtgatt tctttgattg ttttgatgtc atctggtgtc aagccttgtt ttgcagctgc
    23041 ataaatttct gcgattcctt ttccttcgcc attaccactt gcactttgtt cgctatacgc
    23101 agctaagtta ggcattggta atggaaattg gaattgattg atgacgtctt cttcacggta
    23161 accaccgagc gttgaatctg ccgttaaaat gatagcttta gcccctgctt ctactgcttt
    23221 gttcaaaatg aactcattga atctgtcgtc tttactcata tataattgga aaaactgcgg
    23281 tgcgcctggc gctgcatcgg ctgcgtcttt gattgtcgta tttgcataag tgctgatgga
    23341 aaagattgat ccagcagcag ctactccttt agctgtatca gcttcccctt tttcatgtgc
    23401 caatccttgg gccgctgatg gcgcttggat aatcggtgta tctaattcaa ttccgaaaac
    23461 agatgtatgc aaatcggctg agtcgattcc gcgtaatatc cgtggcatga ttttctttgt
    23521 attaaaagaa gtcgtatttt ctttcatcgt ccactcatct tcagaaccac cgcgaatata
    23581 gccaaaagct cctgcttcca tgcgctcttt tacacgacct tctagttagg caatgtttac
    23641 aatatcgatt ggatgttctt cattacttgt atgataagtc atagtagatc cttctttcat
    23701 cttcttgatt acatataaat catactaaac ttacaaaaag taagcaaaca tttactctca
    23761 gatactttta tcgctattct ttccaaataa atcgacttac aagctgatct acttcttggt
    23821 tttcatgaag catactatga gaggcatttt cacctgtcac tactttttcc tctatttcat
    23881 ttccgcgttg cttcaacaac gcatagaccg ctaatgcact gtttaacggt actgttccat
    23941 cactcaagtc tgtttcatct agttgaccag caatcaagaa aaatcgagtg gttataggaa
    24001 tattaccgat catttgctgg taatcttgat agcggttaga aacgacagca ggcccctttg
    24061 ctaactcatc tgtcagagac tgcgcactat catcgacaaa atcattaaaa ggcgcgccaa
    24121 ttgctgttaa tgtctgaact tgtggcaatg acgtatcctg tccatacgtt cctaaatagc
    24181 gtagtgcact aactcctccc atggaatgcc ccactatgtt gactttatct atgccgtagt
    24241 tttctttcag atacaaaaga caagttttga tccattctgc ttgattccac tcgttatttt
    24301 tattatcttc aaacaatact tggaccatcg gattgtctgc ttttccagac aaatctcctg
    24361 ttgcttgtat ttgtccatct gttcctactg ttaaaaccaa ttcttttact gcttgctgat
    24421 ttttttccaa acgccgcaac atccctttaa aggaattttc tgtcccgctg tagccgtgga
    24481 aaaaaagtgt tggaatagtg gttttttcta tcactttact ggattctgcc gttttttctt
    24541 tatcagaaac ttcagtagta tttatcttcg tcgtctggca accacttaac gcaaacaaac
    24601 tgataaggac taaagctgct gcagttgcac gtttgcataa atttttgatt ggttctgtca
    24661 tacacctctt cctttccata tagaaaaaag aaagacttga aaggccaatc atatgatcga
    24721 catttcaagt ctctttatta atcgatttta tctacttgat cgaaatcaag ttctgtactg
    24781 gtttcacgtc caaacatatc gatgttgact ttcaattttt ctttttctcc gtcaacttct
    24841 gttacttgtc cttctaatcc agcaaatgcg ccttcgatga ttttcacgac ttcgccaact
    24901 tctacttcta gatcattttg tcgcaggctc ataccgatag aacgcaagat atgattgact
    24961 tcttctggaa gtaatggtgc tggtttgctt ccggctccgt gtgaaccaac gaatcctgtc
    25021 acaccaggtg tgttgcggac aacataccat gaagcgtctg tcatgatcat ttcaacaagt
    25081 acgtatcctg ggaatgtttt atgaacgatt tctttttctt tcccattttt gacttcagtt
    25141 tctttttctt caggaacaac gacacggaaa ataaagtcgg ccattttcat actttgcgca
    25201 cgagattcga tatttgcttt tactttgttt tcatatcctg aatatgtatg caagacatac
    25261 cagttttttt caaaagattc cattgaaggc tcctcatttc attgtaaaat aaaaaaacct
    25321 cagtacaccc gaagtttttc tttcgcttca ttatagcact aaaagtacgt tgtggctagc
    25381 gagttatttt aaaatccagc caaataagct ttggatggct gtatccatta cgtaaaacat
    25441 caatccgaaa ataatagaag tttcgatgac tactaacgta tctttacgga gttgttttct
    25501 gcttggccaa gttacttgtt tgatttcatc ttttacgctt tttagaaatt tcatgagaca
    25561 acctcccttg ctactgttta tttcgtttct ttatgtaatg tatattgatt acaatattta
    25621 caaaacttat tgatttccaa acgttcgccg ctttttcctt cactgactga ttttgtgtag
    25681 ttgcgagacc cacaaacgga acaagcgagt gctgcttttt tctttgccat ttacttctgc
    25741 ccccttgctg agaatcagac ttatacttca taacagtatc acgtaacttt ttacttgtca
    25801 atttgtgaaa taaactatct attgttttgg ataaaattat gatatgatta atttgaaatt
    25861 aagctaaaat gagacaattg gaggtatagc gatgctatta aaaacacttg tatataagaa
    25921 aaaagatctg acaaccgtta cagagactag tacattagaa gaagcattaa aaattttaga
    25981 aacttccgga taccgttgtg tgccgatctt agattcttca ggtaatattt tccgtggaaa
    26041 catttacaaa atgcatatct atcgtcataa agcaaatggc ggtgatatga cgcttcctgt
    26101 cactcatctt ttgaaaaacg ctacaaagtt catttacctg gatacttctt tcttcaaagt
    26161 attctttacg atcaaagagc ttccttatat tgctgtcctt gacagtgaaa atcattttta
    26221 tggtattttg acacatagta cgttgcttaa tatgctctct caatcttgga gcgtagaaca
    26281 aggaagctat gtactgacaa ttgcttccac aggaaagcaa ggagatttgg ctgctattgc
    26341 aaaaatcatt tcaaaacaca gcagcattgc cagctgtatt actcttgata tcgaaaaaga
    26401 cgaatacatt cgacgtacat tgatcacgct accggctaac actgaagcga aagtatgtga
    26461 aacgatcgtc aaccacttag agaaaaagaa ttataaagtg gtagaaattg aaaatttgca
    26521 aaaccaagaa gcataatcaa aaagcgaaaa aagaaaacag ctaatctgct ttcttttttc
    26581 gctttttata attagacacg cttttcaaaa tcaagcgcgc gatctaaata atacatcaat
    26641 ggtgctgaaa cagccatgac gataaactca cttaatgcaa gcgtgccata ggttgtccaa
    26701 aatgcttggc cacctgttgg aactaacata taagcaatca gtcccatgct gatggtaaag
    26761 aagatcgtgt tcaatactaa acgcatcttt acatttttca ctttgttttg caataaagct
    26821 gtcaggccta aagaaagcaa tgtttggccg ccaccaaaaa ccacatccat gataccaaaa
    26881 ccaaagaagg cattatagac gatgaccccg cctaaaactc cccaaagcaa tttacggtta
    26941 aagacaacta aatgattcaa actttctgaa atacgaaact ggatcggccc tgaggataca
    27001 ggcgcaacta aaatagttaa cgctagataa agagccatga tgatgccatt tacaacgatt
    27061 acggataacc gttgtctgct tttcgttttt tgcattttct ctcctctttt ctcctagttt
    27121 ttttaacgcg ggatggttga tgaaccgcgg ttatgtgaaa caaacaataa ttataacaga
    27181 cttttcattt atttcaatcc gtcttatctg cttttaaaaa agcaaaagct taaacaatgt
    27241 aaacgtttgc taaaaatcgt gggatatggt ataaagtaag tgtaaggggt cataagaatt
    27301 cccagtaaag cagacgaagt aggatctgca agaacagaat tgttgtgaaa cttaaataaa
    27361 taaaaaagga tgtgggaatt tgagcaacct cttactagag aacggtctag caagcagctg
    27421 aagatctaag tggacatgcc gaaccttgga acttctcctt acgtaagtaa tggatcatgc
    27481 gcttgctagg cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct
    27541 gctataataa ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca
    27601 ttcaaaaaat agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat
    27661 atcttgtttt attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa
    27721 tccatcggca ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa
    27781 aaataagcat attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat
    27841 tgctgaaact ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat
    27901 cgatactttc ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga
    27961 tactttctat cagatggaag tagaattccc agttgcttat attccagcag gttctggaga
    28021 tgattttgct cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt
    28081 agcagctcaa tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa
    28141 aaaaggaata gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac
    28201 aaatcattct tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt
    28261 attctctatt ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg
    28321 aggaaaacaa ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt
    28381 tggcggagga atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt
    28441 cgtggtcgaa cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa
    28501 aaaacaattg aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc
    28561 aacaacaccg caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat
    28621 cacaataacc acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct
    28681 acatctggaa caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct
    28741 ttttttacta tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt
    28801 acccaaaata aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt
    28861 gaaccaaaaa gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt
    28921 attttgaaca aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa
    28981 gtattctgct ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt
    29041 gatcccaccg ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat
    29101 gatcggcaat aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga
    29161 ggtgtggatc actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta
    29221 actaatcaaa ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg
    29281 gtttcgttta ctgatctctt tgcgattaaa tgctagattg atgacgctga aaccgctaaa
    29341 aatggataga aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt
    29401 catccgctga ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg
    29461 tgtctgttcc atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg
    29521 caaaaaggtg ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg
    29581 tatcttgatc gtcggcatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg
    29641 taagataatg tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc
    29701 atccaatgta acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg
    29761 cgactcttct tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc
    29821 aatattttgc gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt
    29881 cgatttattt gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc
    29941 tttccatcca agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat
    30001 tggtataaaa actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca
    30061 agttgacgag atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt
    30121 gttccgaccc catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc
    30181 tatccttttg caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa
    30241 tcgcacacaa cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt
    30301 ctacttgata gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg
    30361 taaagcttgc tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca
    30421 agcgaatacc atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca
    30481 tcgtcccgta gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca
    30541 tattacgacc tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg
    30601 gcgcgagatc aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta
    30661 aaaattgatc catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga
    30721 gcgaaacaga tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt
    30781 cattcgcttc tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga
    30841 cttgttctaa gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa
    30901 ttccagtatt aatcgtttcg agattgccac cttgatcaat ctcgccaaag gccgccataa
    30961 acatcaatcc taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca
    31021 gcagtatttt tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct
    31081 ctcaaatcct tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct
    31141 atttttccgt aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta
    31201 tttagttcag tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct
    31261 attgttcgct gacaacacgt tttctgggag taatgggatg tcgatcgtca aacgatccgc
    31321 cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc
    31381 catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac
    31441 aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg
    31501 ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc
    31561 acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac
    31621 atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt
    31681 ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa
    31741 gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt
    31801 cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca
    31861 gttgatggca gtcgatttcc cactgccgtt tggtcctaac agacctaaga cttctccttc
    31921 ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt
    31981 atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa
    32041 taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa
    32101 tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta
    32161 tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga
    32221 tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc
    32281 aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga
    32341 cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt
    32401 tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc
    32461 tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt
    32521 acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag
    32581 cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa
    32641 ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg
    32701 gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg
    32761 ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat
    32821 cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga
    32881 ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca
    32941 tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt
    33001 ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa
    33061 aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg
    33121 gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg
    33181 agggacacca atgataacag tagtcattat tgagatgatc catttgtgac gaaatcgtta
    33241 caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca ttgtgccaag
    33301 gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    33361 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    33421 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    33481 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    33541 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    33601 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    33661 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    33721 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    33781 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    33841 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    33901 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    33961 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    34021 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    34081 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    34141 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    34201 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    34261 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    34321 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    34381 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    34441 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    34501 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    34561 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    34621 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    34681 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    34741 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    34801 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    34861 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    34921 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    34981 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    35041 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    35101 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    35161 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    35221 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    35281 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    35341 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    35401 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    35461 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    35521 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    35581 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    35641 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    35701 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    35761 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    35821 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    35881 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    35941 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    36001 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    36061 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    36121 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    36181 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    36241 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    36301 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    36361 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    36421 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    36481 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    36541 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    36601 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    36661 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    36721 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    36781 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    36841 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    36901 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    36961 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    37021 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    37081 agtgggccat ctttatgttg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    37141 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    37201 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    37261 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    37321 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    37381 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    37441 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    37501 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    37561 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    37621 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    37681 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    37741 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    37801 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    37861 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    37921 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    37981 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    38041 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    38101 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    38161 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    38221 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    38281 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    38341 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    38401 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    38461 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    38521 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    38581 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    38641 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    38701 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    38761 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    38821 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    38881 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    38941 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    39001 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    39061 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    39121 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    39181 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    39241 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    39301 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    39361 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    39421 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    39481 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    39541 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    39601 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    39661 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    39721 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    39781 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    39841 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    39901 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    39961 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    40021 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    40081 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    40141 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    40201 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    40261 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    40321 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    40381 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    40441 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    40501 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    40561 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    40621 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    40681 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    40741 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    40801 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    40861 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    40921 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    40981 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    41041 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    41101 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    41161 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    41221 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    41281 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    41341 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    41401 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    41461 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    41521 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    41581 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    41641 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    41701 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    41761 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    41821 ctttgcaaaa agcatcaaac cagatgtatc ccgatctagt cgcgtcacca catggattac
    41881 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    41941 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    42001 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    42061 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    42121 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    42181 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    42241 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    42301 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    42361 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    42421 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    42481 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    42541 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    42601 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    42661 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    42721 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    42781 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    42841 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    42901 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    42961 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    43021 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    43081 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    43141 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    43201 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    43261 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    43321 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    43381 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    43441 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    43501 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    43561 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    43621 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    43681 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    43741 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    43801 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    43861 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    43921 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    43981 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    44041 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    44101 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    44161 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    44221 accggaaagc ttacaacaaa acgggctgaa ttccctattg aagaaggact tttagctatt
    44281 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    44341 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    44401 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    44461 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    44521 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    44581 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    44641 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    44701 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    44761 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    44821 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    44881 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    44941 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    45001 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    45061 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    45121 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    45181 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa
    45241 aatacgtcga ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat
    45301 caaaaataga aagccttata aacgatcgat caattcttct aattcattta gacgttgttc
    45361 aaacatcgac attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt
    45421 cattacttcc acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag
    45481 tgcctctggt tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt
    45541 cgagtattgg aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt
    45601 aatttctggg tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact
    45661 atcacttagg tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg
    45721 ctcgaattca gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg
    45781 gttgagtaca taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag
    45841 gatattttca ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac
    45901 ataaggctgg ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag
    45961 cgtaaatagc tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata
    46021 gcttcccgaa gaataagcat cgcttcgttt ccctttattt tcgacaacat cgatccaacg
    46081 ttcagagaat gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc
    46141 taaagctttt tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg
    46201 tgtataaaga tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat
    46261 gtatcgatgt aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact
    46321 ttcaggaata tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt
    46381 cgctttaaaa ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa
    46441 ttgttcgtaa acactgtaca atcccttaaa tgctgcttcg cgcacccttc gatccgtgct
    46501 ttctagcaac tgaccataca cgccatgaga taattggact atttcaccat tttctccttc
    46561 aatcgttgga aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc
    46621 aaagatttca cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg
    46681 attatctact atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa
    46741 atattgccaa atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc
    46801 ttcactaact ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt
    46861 tccagtgtct tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata
    46921 aaccctcaat acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc
    46981 tttgtgtttt tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc
    47041 ttggtcgctt gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg
    47101 ttttggcaac tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat
    47161 caaaatagat catagtctaa catccacatg tcacagcatc taacttttct actcattcat
    47221 gtgtctgctt ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc
    47281 tagcctattt ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa
    47341 actgctgata gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt
    47401 ttatttggca aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt
    47461 acaacattcg ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat
    47521 agatccacga tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg
    47581 atactgtatt cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac
    47641 tcactttttc tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt
    47701 taaggtccct actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag
    47761 tctctgtaat atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat
    47821 gcactcctct ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt
    47881 gtccaagaaa agaattacca agtatccacc atacttggta actgttattc aaataatttt
    47941 gggttctttc aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat
    48001 tcgccaacaa aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg
    48061 gttctactga ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg
    48121 attctctttc actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt
    48181 ttttctttcc ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc
    48241 ctttttctgc atgtttagca aaacagcact tattatattc attcattgca agcagcattt
    48301 ttctccctct gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa
    48361 aaagctattc tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc
    48421 gtttggttgg gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga
    48481 ctgcgacaca atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt
    48541 tcgttcgctc gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg
    48601 gtgtacgatc gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg
    48661 cttggttgag attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat
    48721 acaaatcagt ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa
    48781 aatcttcaaa agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt
    48841 cttcctccgg atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat
    48901 caacagtaga atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca
    48961 gttctaatcc gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact
    49021 cctcttcgat atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat
    49081 tgccaagtaa atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta
    49141 cacggatcgt attttcatta atatgttcca tttccatttt gctacacctc actttgccac
    49201 aatgtttaat atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg
    49261 ctgttaagcg aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa
    49321 ctataacatt tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc
    49381 tatttttcgt gcaatcatca tcttctacta cctttttata catctaatca agaatacttt
    49441 ttgtaaaaac aaaaaaactt ggaaaaacta tctttgtaat agt
//
LOCUS       DAXLPQ010000015        47920 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.015, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000015 DAXLPQ010000000
VERSION     DAXLPQ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47920
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.015"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(37..1188)
                     /locus_tag="ACF3UO_001084"
     CDS             complement(37..1188)
                     /locus_tag="ACF3UO_001084"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFD3657125.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1201..1638)
                     /locus_tag="ACF3UO_001085"
     CDS             complement(1201..1638)
                     /locus_tag="ACF3UO_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3657126.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1653..3419)
                     /locus_tag="ACF3UO_001086"
     CDS             complement(1653..3419)
                     /locus_tag="ACF3UO_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFD3657127.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3683..4360
                     /locus_tag="ACF3UO_001087"
     CDS             3683..4360
                     /locus_tag="ACF3UO_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3657128.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4363..5490
                     /locus_tag="ACF3UO_001088"
     CDS             4363..5490
                     /locus_tag="ACF3UO_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657129.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5690..6130)
                     /locus_tag="ACF3UO_001089"
     CDS             complement(5690..6130)
                     /locus_tag="ACF3UO_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3657130.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6141..8174)
                     /locus_tag="ACF3UO_001090"
     CDS             complement(6141..8174)
                     /locus_tag="ACF3UO_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFD3657131.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8176..9879)
                     /locus_tag="ACF3UO_001091"
     CDS             complement(8176..9879)
                     /locus_tag="ACF3UO_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3657132.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9973..10923)
                     /gene="manA"
                     /locus_tag="ACF3UO_001092"
     CDS             complement(9973..10923)
                     /gene="manA"
                     /locus_tag="ACF3UO_001092"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFD3657133.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10962..11987)
                     /locus_tag="ACF3UO_001093"
     CDS             complement(10962..11987)
                     /locus_tag="ACF3UO_001093"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFD3657134.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12196..13065)
                     /locus_tag="ACF3UO_001094"
     CDS             complement(12196..13065)
                     /locus_tag="ACF3UO_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3657135.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13524..15416)
                     /locus_tag="ACF3UO_001095"
     CDS             complement(13524..15416)
                     /locus_tag="ACF3UO_001095"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657136.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15413..17140)
                     /locus_tag="ACF3UO_001096"
     CDS             complement(15413..17140)
                     /locus_tag="ACF3UO_001096"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657137.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17156..17806)
                     /locus_tag="ACF3UO_001097"
     CDS             complement(17156..17806)
                     /locus_tag="ACF3UO_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFD3657138.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18010..18306
                     /locus_tag="ACF3UO_001098"
     CDS             18010..18306
                     /locus_tag="ACF3UO_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3657139.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18478..19098
                     /locus_tag="ACF3UO_001099"
     CDS             18478..19098
                     /locus_tag="ACF3UO_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3657140.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19190..20356)
                     /locus_tag="ACF3UO_001100"
     CDS             complement(19190..20356)
                     /locus_tag="ACF3UO_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3657141.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20368..20721)
                     /locus_tag="ACF3UO_001101"
     CDS             complement(20368..20721)
                     /locus_tag="ACF3UO_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFD3657142.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20849..21871
                     /locus_tag="ACF3UO_001102"
     CDS             20849..21871
                     /locus_tag="ACF3UO_001102"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFD3657143.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21890..22051
                     /locus_tag="ACF3UO_001103"
     CDS             21890..22051
                     /locus_tag="ACF3UO_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657144.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22310..22744)
                     /locus_tag="ACF3UO_001104"
     CDS             complement(22310..22744)
                     /locus_tag="ACF3UO_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657145.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22854..24713)
                     /locus_tag="ACF3UO_001105"
     CDS             complement(22854..24713)
                     /locus_tag="ACF3UO_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3657146.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            24714..24854
                     /locus_tag="ACF3UO_001106"
     CDS             24714..24854
                     /locus_tag="ACF3UO_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFD3657147.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(24831..25991)
                     /locus_tag="ACF3UO_001107"
     CDS             complement(24831..25991)
                     /locus_tag="ACF3UO_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3657148.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26298..27722)
                     /gene="araA"
                     /locus_tag="ACF3UO_001108"
     CDS             complement(26298..27722)
                     /gene="araA"
                     /locus_tag="ACF3UO_001108"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFD3657149.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27738..28436)
                     /locus_tag="ACF3UO_001109"
     CDS             complement(27738..28436)
                     /locus_tag="ACF3UO_001109"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFD3657150.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28393..30054)
                     /locus_tag="ACF3UO_001110"
     CDS             complement(28393..30054)
                     /locus_tag="ACF3UO_001110"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFD3657151.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30272..31672
                     /locus_tag="ACF3UO_001111"
     CDS             30272..31672
                     /locus_tag="ACF3UO_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFD3657152.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31924..33003)
                     /locus_tag="ACF3UO_001112"
     CDS             complement(31924..33003)
                     /locus_tag="ACF3UO_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3657153.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33089..34048)
                     /locus_tag="ACF3UO_001113"
     CDS             complement(33089..34048)
                     /locus_tag="ACF3UO_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFD3657154.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34060..35571)
                     /locus_tag="ACF3UO_001114"
     CDS             complement(34060..35571)
                     /locus_tag="ACF3UO_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFD3657155.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35593..36156)
                     /locus_tag="ACF3UO_001115"
     CDS             complement(35593..36156)
                     /locus_tag="ACF3UO_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3657156.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36162..37025)
                     /locus_tag="ACF3UO_001116"
     CDS             complement(36162..37025)
                     /locus_tag="ACF3UO_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657157.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37039..37935)
                     /locus_tag="ACF3UO_001117"
     CDS             complement(37039..37935)
                     /locus_tag="ACF3UO_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657158.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38110..39399)
                     /locus_tag="ACF3UO_001118"
     CDS             complement(38110..39399)
                     /locus_tag="ACF3UO_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3657159.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39371..40888)
                     /locus_tag="ACF3UO_001119"
     CDS             complement(39371..40888)
                     /locus_tag="ACF3UO_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFD3657160.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41086..41976
                     /locus_tag="ACF3UO_001120"
     CDS             41086..41976
                     /locus_tag="ACF3UO_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFD3657161.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42049..42873)
                     /gene="nadE"
                     /locus_tag="ACF3UO_001121"
     CDS             complement(42049..42873)
                     /gene="nadE"
                     /locus_tag="ACF3UO_001121"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFD3657162.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42885..44357)
                     /locus_tag="ACF3UO_001122"
     CDS             complement(42885..44357)
                     /locus_tag="ACF3UO_001122"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFD3657163.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44994..45356)
                     /locus_tag="ACF3UO_001123"
     CDS             complement(44994..45356)
                     /locus_tag="ACF3UO_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFD3657164.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45579..46331
                     /locus_tag="ACF3UO_001124"
     CDS             45579..46331
                     /locus_tag="ACF3UO_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3657165.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46471..47394)
                     /locus_tag="ACF3UO_001125"
     CDS             complement(46471..47394)
                     /locus_tag="ACF3UO_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657166.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47409..47681)
                     /locus_tag="ACF3UO_001126"
     CDS             complement(47409..47681)
                     /locus_tag="ACF3UO_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657167.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        13961 a         9950 c         8261 g        15748 t
ORIGIN      
        1 aaaatttcgt cacattcccc tttttcgtat cctattttaa gcgacttgct tggcataacg
       61 gttcacgttt tgcttgatat tcccgattgt tttcggatca ttgattcctg tgacttcttg
      121 aatcaattgt tccaagtttt catggatctt catttcatgc aattgacggc tttgttcatc
      181 ttcaggatca tagtaattaa aaataatccc cattgttgcc gtcaaatgtg ggcaagtcaa
      241 gttatgttct tgtagttctc tcactggacg tgtaaatctt tcttgataac ctaacttacg
      301 taatggtgtc cgagcgacac gtgtgatcgc atcagagata tttttgtttt ggaagcgatg
      361 aatgattttt tcaatatacg catgatgctg ctctgcatca aacccccatt tggcaatcag
      421 caaacttcct gtttcctgca aaactgattt taattgtgcc acaactaacg catcttgcat
      481 tgcttcatca atggtctggt aacctaacaa ggcacctgta taagcgacag tcgcatgacc
      541 agtattgaca ctaaatagtt tgcgttcgat atatggttct agatcatcta catataaaac
      601 cccttttaat tggatttttt tattttttct ttggctatcg tcaatgaccc attctttgaa
      661 aggttccact tggacgaata aaggatcttc atggtgttgt aatgggacga ttcgatcgac
      721 tgctgcattt ggaaagccga tatatttgtc agtaaatgat gtttccggaa gatatttata
      781 cacttctttt tctagaaatg ctgaaccgcc aatcatattt tcacaggcaa tgatatctaa
      841 agatgttgtg cttccttcct tttctctttc ttggatacct tttgcaatca actcagcaat
      901 aaaaggtaag atattcgggc caatggcggt agtaactaaa tctgcttcag cgatttcttg
      961 gattactttt tctggatttg tttgattgtt gattcctttg acatttttta cagtgatttt
     1021 ttcttttgat tcatctgcta attcgatttc gtattctttt ctttcattta aagcatcaat
     1081 gatcgtgtga ttcacatcta cgaaagtaat ctcaaatcca ttagctgcca aaacctctcc
     1141 aataaatcct cgaccgatat ttcctgcacc aaaatgtact gctctcattt ttctctctcc
     1201 ttaagcaatt gctagatttt ccgttacttc ttctttgctg agcgcgtctg ctagctggac
     1261 aacattgtcc atatcactgc aataaagtgc gatttgctgt acaagttgca aatgctcatc
     1321 tccgactcct gcaataccga acaaaacagt cgcaatcttt tcttcttctt cggtaccaaa
     1381 atctacacca tctggtactt gaacgacaca gatgccggat tttttcacat atttttttgc
     1441 ttcatctgtt ccatgaggaa tcgcgataaa attccccata taaacagata acattttgtc
     1501 tctatctacc atggcatcga tatattcctc atcaacgcac cctgcttcta caagcatctg
     1561 accgcaatag cggatcgctt cttctttggt tttaaaagat cgattgagct cgatcatgtc
     1621 gaatggcaaa ctttgcatgc tgttttcctc ccttaagctg tctgtttcaa atattgtgca
     1681 atcgattcgt atttttgcgg attgaccatg ctgttgactg ataaatgaat ggattgaggt
     1741 gcagccatct gtactttttc cgctaaactt tctttggcta cgatcagtga atcaggttca
     1801 tcttttaaat cttggatatt gacttttctt aacgggatag ttaaatggtt cttgtctaat
     1861 atatctttga gcacggtcat ccccattgtt gctgatccgg aacgatcatc gtggacaagt
     1921 agaatctctt tgatttgttt gatgtttgct gaaagaaact cttctgctgg ctcattctca
     1981 atttcagaaa ctgatgtttt ctgcttgctg cttaattctt gaatgatttc atcatatcga
     2041 ggtgaattca aaaagttttc tactgagaca aaacgcgcgc tcggtgcttt ttgttttgct
     2101 ctttcttgta gttcgacctg agtaacgatc aatgtattcg agtcatctgt cagttggctg
     2161 attgcttgat tggtcaccgt ttgaggcaag tctgcttcct gtactttttt tctcaagatc
     2221 gaagcgccca tcgcacttga tcccattcct gcatcacaag caaaaatgat tttttgtacg
     2281 ccagagaatg tagctccttg aggaatacct tgggcacctt tggaagcttg cttagctgcc
     2341 tttgtctctt gaacagattt ttcgaagtct tcatttgtat ctttcgcatc cgctttcaaa
     2401 attactgcag aaataccaaa cgaaacagct gcggcaacaa tcacgcccaa aataacagga
     2461 aggtaagaat tgaacggtgt catcgctaga atcgcaatga tcgaccctgg agaagctggc
     2521 gctcttagtc cagcatccat caattggaaa atgaaacttc ctgacattcc tccgcctata
     2581 actgataaga ataataacgg tttcatcata acgtaaggaa aatagatttc atggatcccg
     2641 cctaaaaagt gaatgatcat ggctcctggt gctgaagatt ttgctgctcc tttgccaaac
     2701 aaagtaaaag caagtaatac gccaagtcct ggaccaggat ttgcttcaag caagaataga
     2761 atagattttc cagcctctgc tacttgttca gttcccaatg gtgtcaaaat cccatgattg
     2821 attgcattat tcaaaaataa gatttttgct ggttcaataa aaatacttgt caatggaatc
     2881 aaatgggcag ataaaatgat ctctacacct tttgccattg cttgagtcaa tgcatcgaca
     2941 actggaccaa tcgcagaaaa acctaataac gctaatccaa aaccgataag acctgctgaa
     3001 aaattattga ctagcatttc aaaaccggat ttgatccgtt tttggaatag ctgatcaaat
     3061 ttcttgatgg catatccacc aagaggtccc atgatcatcg cgcctagcat cattggaata
     3121 tctgttccga caatcacacc catcgttgca attgccccaa caactgatcc gcggtcacca
     3181 gcaattactt ttccgccagt ataaccgatc aataaaggaa tcagataagt tagcattggg
     3241 cttaccatgg tagccaaagc ctcatttggt aaataaccat ctgggataaa tagagccgtt
     3301 aatacacccc aggcaatcag tgctccaata tttggcatga ccatgcttga taaagtactg
     3361 cctaattttt gtaccctcgc ttttagcgaa atgttgtttt tgggaatcgt ccgttccatt
     3421 ttgtctctcc ctctctcctt ttgatactct aattgtatcc gcttactaaa aagagaaata
     3481 gtcgtacttt ggcacgaaac tttgtgccaa aggtttgagt atgtcagcaa aataaaaaga
     3541 tttcggtatc agaaaacttc aattttaaat aaaactgtta ttttaatttt tttataatat
     3601 gcaaacaata acttttgtta gcatttaatt tagatgtttt ccattctatt atgttattaa
     3661 attttatatt ggaggcctat ctatgacatt actgatcaaa aacatgaaca tgaaacgtgg
     3721 taaaaaacgt gtgattcgac aattgaatct tttagtagaa tcaggagaag tagctgcttt
     3781 gattgccccg aacggatttg gcaaaacaac tttgctgaat ggcattgccc aactgctgcc
     3841 aacaacttat gatcaattgt cccttcacaa catctctcct actgcttata cagattatcg
     3901 ccggtctttc ttttttctag aatcaacgaa tcagttatcc gactatctat cggctgttga
     3961 ttatttgact ttgatcaaat actattggca gagcaaagta gaatgccaaa ctgttttcca
     4021 acgattgaag atgactgagt accttacttt gccgattgga aaaatgtctc taggaatgaa
     4081 acaacatgtc ttgcttgctg cttacttgat cagtgattca tctgtcatgt tattcgatga
     4141 accgttgaac ggattagacc caggaagtat tgatatcttg aatagcctca tcagacaatg
     4201 gcagaaagag gggaagacga ttcttctttc ttcccacgct atcgcgaata tccaatcgat
     4261 ttgttctaaa gcatgttttc taaaaaatgg agaaatcgtc acagaatcct caaatatgga
     4321 agagatttta gctatttatc gtaaattata tgaggtgtaa ctatgtcttt acttacattt
     4381 gaacgcaatc tcttactaaa aaacaaagta aactttttat ttcctctatt gttggtcgtg
     4441 ctctttgcat tcccactttt ttttgatcat aaacttgctt atacagaatt cgatgaactg
     4501 aatcataact atgaagagat gcaacgtttg attgaaacgt tgaaagaaga tgagaatgag
     4561 aaagaatttg tggaaagttt agagaaaagc aacaaactga tcgaagcaat cttacatgca
     4621 aaaaacacag ggaatgtcca gcaaatggtc gaagcaactt atcattatga aaaagatata
     4681 ctggatcgac tgatttctgg tcaaagacaa ggaattccaa tcattgaaca acaaaaacgt
     4741 gtcgagttgc tccgttatat gaaagaacat cagatccaaa gatattctat ttttgacttg
     4801 ccagcgcatc tccctttagc aaattactac gaaaatattt tttcaggaat gatttctagt
     4861 tttttgattt tatgtataac cgccttgttt ctttcttcca tcatctctta tgaaaaaaga
     4921 aagcaggtaa tctctctagt caatctatta ccggatagta tggtaaagaa acatagcatc
     4981 cgttttacca tttattatgg tgcagctatg ctaagtctcg tgatgccatt tttgatcgtc
     5041 tctatactag taataatcaa aaatggtttg ggagacttcc gttatcctgt aggaacgatc
     5101 attggtcagg agatacgaat ccttccgatg tatgagtatc ttttccagag ctttctgttc
     5161 ctgttgttgt gggtgctctt tttaagtaca atcagttttc ttctatctgc tttatttgaa
     5221 cattctctag tcaatctttt aggtacactt ctttgtcttt tcttagcaga gtatcgcttg
     5281 ttttcttcga ttggatggat agaatcaatc agtcattact tgccaacttc ttatgttgat
     5341 tttcaaaatg tgatcatagg aggagatatt ttctcgccac tagcttcaga acaggttact
     5401 ttcatgaatg gtatcttgac acttggtata tggagtatcg ttttattatt cataggtatg
     5461 ggcactatct atataaaaaa gagctattaa aacacaaaaa taataggggc ggtgacaaaa
     5521 accttgtcac cgtcccctat ttcaaataaa cggttttcta gaataaatag ttttcaaaag
     5581 cttgcatccg cagtaataag aacctcccaa caaaaatagc tcctcttatt tttatcttgg
     5641 ttgaagttat tacttgatgc aaggcagctt tttttactgt gaacattggt tatatatgtc
     5701 catgttcaaa aatcatttgg acttcttcaa tggttttcgc atcactgagc gccattactt
     5761 ggtcgatgtc tgaacagaaa aaggctaaat cttggagcac cgctaactga tgttcttttt
     5821 ttaaagccac tacaaataag agtgtcgcga tttttggttc ctcttttgtt ccaaagtcca
     5881 caccatcagg cacttggact aaatagattc cttcttctac tacttcttca tctttgtcag
     5941 tcccatgtgg caaggctacg aaattcccga tatagacact cgctttttct tgtctttcga
     6001 tcattgattg gatatatgcc ggtttgattc ccccttgttg ggtcatccac tggccgatct
     6061 cggtcaacgc ttctttccaa ttttgatagg attgatcgag caatattttt tctgctggta
     6121 gctgtatcat cttttcacct tcatttcttt atttcttcaa tcaggatttt cgctaacaac
     6181 tgataaacga tttctttatt tcctgagcgg aagatctcgg tgttcaagtc attcatgatg
     6241 attgctccac tgatctttcc taaaagaatc ccgtcttttt cttggattgg cgaaggcgcc
     6301 agcataacta acatacggga caaatcgact ggctgtctat ccatcccttc aatggtcaac
     6361 ggatgtttca aattgaaaat acaaaagatc ggtttagaaa tcaatgagct ggatgtatgg
     6421 aataacccca tatttgtatg aggaataccg ataggtgctt gttcatatcg cttaagcagc
     6481 cggcgatgaa ccacctcttc atccgttact agtccttcag gaaaataagg aaataagctg
     6541 cgaatcgttt cggaaatcgt ctcaggatta tccagttctt ggataaaaaa acgaccgagt
     6601 aattgattga tttgatccat gaaatgcatt gtttcctcat aagtatcttc tatcatccac
     6661 tcgttattgc tgttatacgt aattttttgc ctttttttct tctcaatatg cgaaaaagct
     6721 tcttttagct gcttgacttc atcttctagc agtagcgggg agactaaaat atattttcca
     6781 ccgtatcctg gtaaaataga tgtagaaata acaacatcat attcttcttg taaatcgatt
     6841 ttttttaaat cagcaatccg atagaaatga atttgttgga tgaagggaaa ataccttttc
     6901 aatcgtagtt ccaacatgct agtagaagct aatccacttg gcgaaaatcc tgcaatactg
     6961 atattgcttt ctttcggact tcgttccaat gaattcgcaa aatgaaggac catataagcg
     7021 atctcttctt cggataattt tttttcttga aaaatccgct ctactgcttt acggattgca
     7081 ttcgcaactt cctcgtattg aaccatgatt ttttctaaaa tcggattggt cagtgtctct
     7141 tcttgtaaaa cggctcttga aaacacacca gataaatgag tcaacagcat tttgtacaaa
     7201 gtttcatctt cataaaaatg gacattcgtc tcttcactta cttcttgaat cagttgtttt
     7261 actaaataag caagctgtgt atcgaacgtc tcttcaaaga aattctgatc aaatgagttc
     7321 gtgaagtcat ttaataatcc tgcaaaaaag acgatctcat ttactggata aagttgtttt
     7381 gtctcagaag cgatccgtga aaacaatcgt ttagctgtct gtagtaattc tttgtttgcc
     7441 agactattat atgtctcatt tgtcagtaaa tgatttttag tcacacgctc catcgtcaat
     7501 gtcagcatca aaaccaaatg ttcaagcttt ctatcactta gattggtctt tttttggatc
     7561 aattcttccc cgattacttt gcgtgcaaga gatagatgtt gcggatcaac gaatcgaaaa
     7621 aaataattca gtgatgcatc gaaagaaata ctatgaaaaa gttcatattc attgatttct
     7681 aattctaata cattcgctgt cagaagccgg cggtattttt ccggtccttc gatctcgtat
     7741 ccctggttcc gaatgatttc caaaggcagt tggcgaatac tttcttccaa ctgtttgata
     7801 tctgcataaa aagtggtatt actgatgcga tatgattcca tgaaatgagc aagactcaac
     7861 ggctctgtcg tcagtaacaa ctcggctaaa atcgcgtgtt gtcgtttagc agtggataag
     7921 tcattacttt tcccatctgt attttctttt aattgctcta atacttcttc tgatgcctca
     7981 atgacaaatg agcctctagc tgcttttttc aaagaagcat ttaccgattt caatgagact
     8041 tcaagattat ctaattcgcg gtaaatagtc cgtttactga ccttcaataa attcatcatt
     8101 ttttggatag atacaggtga cgggctactg agaaattctg ctaataattg tttttctctg
     8161 ggcgataaat acatcttata tttctccctt cacgagtttt tcgtattcat tcgtagctac
     8221 ccaatgttca actagaacta gccgagggat cttttcttct agctgttcag ttacagctag
     8281 ttctctttgt gcgatataaa tcgtttcttc ttggattttg attttttcta ttgattcttt
     8341 tgagataaca aactgttttt tcgctttttt tgctaattga cttaaaatcg tcatgcccat
     8401 agtttgtgag ccgcgtctgt tgtttttata caaaaataca atattagcag gcgacttttt
     8461 ttgttctgtg atatctgcta tctctttttt ttcttcccgc tttggaaatt ggatcgcttc
     8521 ttttattcgt gacagcaaga tatctgtttc caaaaagtga tccagtacat agatttgact
     8581 ttgaggtact ttttctcttg caagacccgc tagttcatgt tgcacgataa ccagctgatt
     8641 tacttggtta ttcaattcat agatagagct gtatccgaca gaaagatcga ttttttctgc
     8701 tgctaatttc tttttcagca gggcggctcc catagcactt gatcccatac ctgagtcgca
     8761 agcaaaaatg acggaatgaa tgatagatgg ttccaagatt tctccccttt ctttgaccgt
     8821 tttgttctct ttttctttat ttggtaattt caatagtatc gctgcacaaa tgaaggtcac
     8881 aaatgtactg attgctatcc ctatacttac cccagctagt tgtggataag gcgcattggc
     8941 aaaaatcacg agtagtgacc caggcgatac aggtgcagct aatcccgtat ctaaccattg
     9001 aaatatcaac gtgccgcttg ccccaccagc cattacagct aaaaatagat acggtcgcag
     9061 caagacaaat ggaaaataga tttcgtgaat cccgccaatc gcatggatca tcaatgctcc
     9121 actcgcattt actttttcct gtttttctgc aaaacaaagg atagaaagta agatccctaa
     9181 accaggtcca ggatttgcct ccatcaaaaa taaggaagag tacccgactg tttgtgagaa
     9241 ttcgattcct aaaggtgtca atacaccatg attgattgca ttattgaaaa atagtacttt
     9301 tagaggttct aagatcagac tgacaagtgg taacagattc attgtgacta gccaagacac
     9361 aacggaggcg agcaacaagt gaacactatt taaaactggt tcaataaaaa cgattccaat
     9421 tatacaaata acgctaccag tcagtcctac tagtaggttg ctgacaagca tttcatatcc
     9481 agccttgaat ttcacgtgga atctagaaac aaattgttca tatacgatgc cggcaagcgg
     9541 cccgataatc atcgctccta cgatttgtgg agcattggaa cgagcgatca accctaaaga
     9601 agcaattgca ccggcgactg cccctttttg tccccctacc gatttcccgc ctgaataact
     9661 gatcaagatg ggtaaaagca gctggatcat ccaatggcat acctcttcta atgtggtgtg
     9721 caaatcgcca gacacacctt ttgttgctaa tgacaagatt ccccaagcga taaacagact
     9781 tagatttggc atgatcattt catttaagtg atgtccagct tttctcagtt gtttcataga
     9841 cacgcgactg ctgttgtttg ctttccattt gtattccatc tttttcacca tacttctatt
     9901 tattgatgga cggattttat gtagaaaaag cagcaaacga aaaaccgtct gctgctttca
     9961 gctatctggg aactatttgc ctggttcagt cgcaatgatt gctagttcac cttggaccgc
    10021 ccactcagaa acgccatttg gaataataca gcttgttcct ttttctaatg gatatgtttt
    10081 tccgtcaacg acaaggtctc ctgctccttc gattaccgtc atcaatgtat aaggggcttg
    10141 ttttttgaaa gatgtgattc ctttaatatc ccactcatat acattgaaaa actcagtttc
    10201 taaataagtg acgatcgatg aattcccttt tcggacttct ttgatttgta attctggtgt
    10261 tttcgcaggg acagttgtta catcgatcga ttgttggata tgcagctctc ttgtttgtcc
    10321 ttgcgcatct tttctgtcgt agtcatacac gcggtaagtc gtgtcagaac tttgctgtgt
    10381 ttctaaaatc atgattcctt taccaatagc atggatcgtt ccgcttggta cataaaagaa
    10441 atcacctttt ttaactggta ctttcttcaa aaggtcatcc cagcgcccat ctttgatcat
    10501 ctcagctagt tcttctcttg tctttgcatg atgaccatag atgatttctg caccaggttc
    10561 agcatcgatg atataccagc attcagtttt tcctaattca ccttcatgtt tcatcccata
    10621 ggcatcatct ggatgtactt gtacagatag atcatcttct gcgtctaaga tcttgatcaa
    10681 taatggaaac actggttctg aaggatggcc aaacaattcc ttgtgttctg accatagttc
    10741 atctaatctt ttccctttga attcgccatt ttctactaca ctgacaccat gaggatgcgc
    10801 actgatcgcc caatcttctc cgattttatc gttagggata tcaaaaccaa agactgaacg
    10861 taaacgactt cctccccaaa ttttttcttg aaaaactggt tttaaaaaca taggttcctg
    10921 cataattcaa actcctctca tttttcatag ctattatagc attatttcgg taataccgct
    10981 ttctctttca aaaagttttc aacaatttca tctcgacata tgagatactc cgcacgatga
    11041 tcgacaggat gtacgcgatt tgacaaaaat atcaacgctt cttgtgtttt tatatcaatc
    11101 aagaaaaacg tacctgtata accagtatga aaaagaatcg catgaccgtc ttctacatcc
    11161 ttttttaagt cccatcctaa agaacgatag ccattttttt tcggtgtttg atcttgcagt
    11221 aaagaatcaa tcgtctcttc ttctaaaaaa cgaccattac ggatttttcc cttgttcaaa
    11281 tacatttgga caaaagtaat gctgtctttc aaatcaataa agagacccgc gttacctgca
    11341 tgttcagcca aaactcttgc tttcggatca tgagtttgtc cacgcaaaac ctcacccgaa
    11401 ggcagttgtt ctgtgggaac gatttttttg gaaggaaaag gaagaaataa gctgttcatc
    11461 attcctaatg gttccaatac ttgttcttga aagatttcca ctgcagtttc ttggtaaatt
    11521 tcctctagca tcaacccaag aagaatcgta ccggcatctg tatattttac ttcttttcct
    11581 agttgctcac ctggttctag cttcaaataa gcggcgatca attcttcctg agatagctta
    11641 tctctgtttg gtatccatgt tttgatatca gaagtatgtg tcagtaaatg acgcaaagtg
    11701 attgtctgat tttcaaattc aggaagatat ttatgaagcg gttgatcgag ttctatcttt
    11761 ccatcttcta atagacgtaa aactaatgaa gtggttgcaa cgactttcgt cagtgaggct
    11821 gcatcaaaca acagatcttc tgtcatcagc tgcttttcag gaacgacttg ggcaaagccg
    11881 gctgtaaatg tttctacttg attttctttt atgaaggcga ctgctacacc tggataaaat
    11941 ccttcttcca tctttttcaa aataagctgt ttcgtgtgtg gatacatctt tttctcctgc
    12001 ttttctatca gattcttaca gtccaagctt aaagcttaat ctatgaggaa tcaacctttt
    12061 ttacacaaaa aaactgcgcg aaaaaccgcg cagtttcccc cggtatacta ttttctcttt
    12121 ctatctctag aataagcgat agtatgaccg ttcataaaat gacgagacat gcgacaatcg
    12181 ttaagaaaga aaaagttaag cgtcgcatcg aatgtcagtt ttattctttt cttttggctc
    12241 actgacgaac caccattcga ttcctatagc atcatagatt gtgagtactg tgtgcttttt
    12301 gtctaagaag aaatcaactg atagttgctg caagtgagca atcagtcctt ccatgctttc
    12361 agtatcgatc atgaatttca gaaaatcaag tccaatcact tcatctgtag gcaaatcaat
    12421 tgcgcctccg ctagcttctg tcaaaccaac atggaaatct ccttcattca atacatggat
    12481 gccctcttct tcattatgta ccttcaaacc aagtacatga ttaagaaatt ggcgttcttt
    12541 tgttaagtta gtaacattta aatggatttt ttcaaaataa gaacctgttg atagtttact
    12601 gaatttttct tcagattttc ttaataatgc ttcttgatcc attgtttctg gaatttctct
    12661 ttggtcgttc ttattctctt catggtaaat ttccaattca ttctcttctg ggtctacgag
    12721 caaaatcccc atacgtccat gatcttctaa agcttctttg attggataat tcattttacg
    12781 gatacgacaa aggatatctg ccatttcttc tgtgctaggg ataatcaatg aaaaacggtt
    12841 cagctttttg atcaccccca tgtgatcatt cgctctagga ctttcttcca gcagcaacat
    12901 ttcacttcca gcttcttctg ttcctaaaat ggctaattcg ttttcttctc ttttcaaatc
    12961 aaagccaaca acgttcttgt aaaaatcaat cattttatct cggtctttca cccgaatggc
    13021 tacacttttt aaataggtgg cagcccccaa ttgaaaatct ttcatatttc ttgctcccct
    13081 ctacgtcaag ctttatttta acgatggatt cttcttcttt caagcaataa ctttgatttt
    13141 gttaaaaaaa atgtgagaaa attcgcattt tgcttgtttt ttgtaaatta atgagtaaaa
    13201 actcttataa aaagaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
    13261 caaaaatagc tcctcctatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt
    13321 gaacaccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat tagagataca
    13381 aaacggaaaa atagcttctc atattttgcc gttttttgag ctaataccga aggacagctg
    13441 attgaacacc gtttattcgg aaaaagggac tgtgacacga cttttgtcac agcccctaaa
    13501 aaaaataata aatttgtact attctatgaa gcttcttctt cagaaaactg actgttataa
    13561 agatctgcat agaatccgtc tttttccatc aatgtatcgt ggtttcctgt ttctacgatc
    13621 gaaccatgat tcatcacaat aatgttgtct gcatcgcgta ttgtagacaa gcggtgagca
    13681 acaacgaaac ttgtccggtt ttccaatagg cggttcatcg ctttttgaat cagtatttct
    13741 gttcgtgtat ctacactaga tgttgcttca tcaaggatca ggacatctgg atttgctaag
    13801 aatgcccgcg caattgtgat tagctgacgc tgcccttgcg aaatattgct tgcatcctcg
    13861 tttaatacag tgttatatcc ttctggcaat ttacgaacaa aatcgtctac gtgagcagct
    13921 ttagcagcct caatgatttg ttcgtctgtt gcatcgtcgt tcccatattt gatattgtca
    13981 tagatacttc ctgtaaacag ccaagtatct tgcagtacca ttgaaaactg tgcgcgcaat
    14041 tcatcacgtg aaagatcacg ggtatctaca ccatcgtaac gaatactacc tccagaaaca
    14101 tcgtagaacc gttcaagaag gttgatcagt gtcgtcttcc ctgcaccagt cggacctaca
    14161 atagcgacca tctcaccagg tttgacatcc aagttaaaat cagtcattag caagttatct
    14221 ggtgtgtagc cgaattgaac attttcaaaa cgaactttgt atggtgtatc tttttcttct
    14281 ggaaggccag atttttcatt ggacatctct tcttcatcca acacttcaaa tacccgttcg
    14341 gctgaagcaa ctgttgattg gatagtgttc atcaaacttg caagttgagt gattggttga
    14401 gagaactgtg ttgtatattg caagaacgct tgaacatccc ctaatgtcat gttcccattt
    14461 gcaactttta ctccgcctag tacagcgacg aacacatagc ctagattttt aacgaaattc
    14521 atcaacggca tgatgattgc cgaaataaat tgagctttcc aaccagcggc atacagattc
    14581 tgattttctt tttcaaatac ttcctggtct ttttcagtat gattgaatgt tttaacaatg
    14641 gtatgaccac catatgtttc ttctacttgg ttattcaata aacctaaact tttttgctga
    14701 tctgcgaaaa acacttgtga tttcggcgct acgatcatca cgatgatcaa gcttaaaggg
    14761 atcatcaata acgcgactaa cgtcaattgc cagctgattg aaagcatcat cacgatgacc
    14821 ccaatcaatg tgactgcact agttacaaat tgagtcaaat tttgctgcag cgtgcttgcg
    14881 atgttatcca tatcattgat tgctcgagac atgatatccc catttgtatg tgtatcataa
    14941 taggaaatcg gtacacgatt cattttggct tccaaatcat gacgtaattc ataaactgtt
    15001 cgttgggaaa cacgtgtcat aataaattgc tgtaaaaagt tgaatacagc agaaatcaaa
    15061 tacatcacga ttactgtcgc aatgatctgc gcgattttat caaagtctat cggaaatttt
    15121 gttacttgtt ggccttgttg catctgttga gcgccagcca ttacaccttt gaatatttct
    15181 gtggttgctt tccccaagac ctttggtgtt tggatttgga agatcacggc tgctattgct
    15241 agtacaaata cagcgatgat cgcaaccata cgtttagaca tatagccaaa caatcggcgt
    15301 accgttcccc agaaattttt aggcttttca ccttttacac cgagatttct gccaggtcca
    15361 ccatgtcctg gaccgcctgc tggtccatga gagggacgtg tgtttgtttt actcatgcta
    15421 agtcctcctc tcttagttgt gaatgaacga tttcttgata agtttcgttt gttgctaata
    15481 gttcttcatg tgttcctttg ccaaccagtt ttccttcatc tagcacaagg atcatatctg
    15541 catccattac tgtacttact cgttgagcaa ctaaaacggt gatactttct ttcatattcg
    15601 ttttcaatgc ttggcgaaga ttggcatccg ttttgaaatc caacgctgag aaggaatcat
    15661 caaacacata gatatctgct gttttgacta atgcccgtgc aattgccaga cgctgtcttt
    15721 gtccaccaga gaagtttcct cctccttgtt ccacatggct atctaagcca tcttccatct
    15781 ctgaaacaaa atctttagct tgtgcgattt ctaatgcttt ccaaatcatt tcatctgttg
    15841 catccggctt accatactgc atattgtctc ggatcgttcc agagaacaga actgcttttt
    15901 gaggaacaaa gcccattaat tctcgcaaat tatattgagt catgtcacta atgtccgttc
    15961 catttatttg gatcgaacca gattcgatgt catataatcg agggatcaaa ttgactaagg
    16021 tcgttttacc tgaaccagtc ccccctatga ttgcgacgat ctcgcccgac ttggcttgga
    16081 aatcaatatc ttccaatgca agtttttctg ctccatgata tcgataattg acatgattga
    16141 aggccaatgt tgcgtttttt ccagcaaaag aaactgtttt aggattttca gggtcatgga
    16201 taccgatttt ttcatccaac acttcattaa tacggtcagc tgaagcttgt gcacgaggca
    16261 ccatgataaa aatagcggaa agcatcataa agctgatcaa gatctgcatc gcataagtca
    16321 taaatgcaat cagattaccg acttccaaag tcatatctgc tatgtagtgt ccaccaaacc
    16381 aagtgattgc tacgtttgta ccgctcatga tcaatgtcat cattggcatc atcaatgcga
    16441 cgatcgtatt aactttgatt gccgtatttg tataatcttt attcgctaaa tcaaaacgat
    16501 tttcttcaaa gcgtgtctta tcgaatgctc gaatcactct gacccctgtc aatccttctc
    16561 gaaataccag gtttaaacgg tcagttttct tttgcatact tttgaataat ggaacagcaa
    16621 agtacatgat tccgccgatc aaaataatca ttactgggat gacaactaag aagatttttg
    16681 tcaactgatg atctttttga taagcaagta tgctcgcgcc aatcaacgtg attggtgcat
    16741 tgatcatcat acgtaaaaac atttgtgtaa ccatttggat ttgagtcaca tcattggtcg
    16801 ttcttgtgat caaagaggcc gttccatatt tatcaaacgc atcttttgtc agactctctg
    16861 attttttata gacatccgta cgcaattgct tacccagttt ctgtgattca cgagtagcaa
    16921 aaaatgtatt tgcgatagca gctaagatac tgatcaaaga aaagccgatc atcacaaaac
    16981 ctgtatgcca aatataatcg acatctcctt gcgctacccc tttatcaata atattggagg
    17041 taagtgtcgg caaatataaa tctgccagta cttggatcac catgaaaact gcagctgcaa
    17101 ttgctgaagt caaggagatc cgttttacga tttttagcat ctagttccct tctttctatt
    17161 tatatactcc gtttttcagc caagaaagtt tcaaattgaa ttcactgatt gcttgctcta
    17221 ctgagtaatc ttcagatgtt gaaaataagc gatacgaatg cgcaattgtt gtaaatacag
    17281 tattcatcac taattggatc agtaattcca attcatgatc attttttact ttcagcttcg
    17341 tccgatcgat caattcaagc aactcttttg catcttgttt gtgttcttta tgtggatcgt
    17401 gaggcgtttt ttggcgactc gtatgaggag cgacttttct tgaggcacgg taatccatgt
    17461 tcataaacaa gttacgataa aaagaagcat tctcgccttc caaaatctca taaatcattt
    17521 tagaaaaata ggattcgaat cctttgaata gatcaccatc ggattctttc attagttgta
    17581 acatatcttt agagctgtca cgtctcattg tctcaaagta ataaaaataa agatcctctt
    17641 tatcttcaaa atactgatag aaactgcctc tagggatatc cgctaatttg acgatattag
    17701 caatcgaagc ttcttttaag ggtactctag aaaactcgat tctcgcagcc tcgattagtc
    17761 ttttttgttt ttctttaggc aaatggaaaa atgtctgtgt cggcatatgg atcctccttt
    17821 ctttcaagat gacacattgt catatgacgc tgtgtcatta taacacctcc tacctgtttt
    17881 gcaagacatt tgcatagttt ttttcattat catccgatac attaaaaaag tgataagagg
    17941 aatccttcca tttgaattaa tgagagttgc ccattaaaat agccacatac taaacaaagg
    18001 atgagataaa tggcccaatc aattagtgtc caagacttca ataaattgcc tctcgatgct
    18061 gacagcatcg ttttagatac aagaaatacc ttagattaca caaaaaacca cttaagccac
    18121 tcgctttcta tccccgctgc tatcttgcca agacaattaa aaaatctaga tccaaagaaa
    18181 ctttattata ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact
    18241 gctaatggtt ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt
    18301 gcttgaatat tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc
    18361 ttttataccc tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag
    18421 ccttttcttt ttctcatagt tataacaatc atagcaataa aaggagaagg taagcatatg
    18481 gcatctgttt tagtagtcaa aggtcatccc ctaactgcag aagaatcgcg cacagttaag
    18541 gcattgacgt cttttttaac aagttataaa gaaaatcatc cagatgatga agtgactgtt
    18601 ttggaacttt atcgcgatga tattccggaa atcgatgaag aattattatc aggttgggaa
    18661 gcattacgtg ctggtgcaga attcacttcc ttatcagaaa gtcaacaaca aaaaattgct
    18721 cgtttcaatg aattgactga tcagttcctt gctgctgata aaatcgttat cgcaaacgcc
    18781 ttatggaatc taaatatccc aacaaaatta aaagcttggt tcgataccgt caatgtagct
    18841 ggaaaaacgt tccgctatac agaaaacggg ccagaaggat tagtgacagg taaaaaagca
    18901 ctgcacatcc aatctaatgg cggtgtatac aacggacaag actttgcctc tcaatatgta
    18961 aaaggtattt taaactttgt aggcatcgat caagtagatc agctattcat cgaaggaatc
    19021 gattatgacc ctgaccgtgc agatgagttg atgcaaaatg cattagataa agctgctgct
    19081 ttaggtaaat cattttaaaa attgagataa atgcatacaa aagagacaga ggaaaaaatc
    19141 ttcaaagcag catttgtacc ttggatattt tcccatctgt ctctttttgt tattctttct
    19201 gctttttcaa cggattttct tcataaagag aagagattgt tgtgtaccat tcaaaaacat
    19261 gagtaatcac tactttagct gctgcataaa caggaatccc caagatcaca ccgatgattc
    19321 cgaacaattt cccagaagtc agcagaacta ataaaatcgt tactggatgg attgctaact
    19381 gattccctag tactaatgga gagatcaagc gtccttctat tgtctgctct actgcaaaaa
    19441 cgatcagtac tttgatgatc atgaatggac ctgctacaat ggctaaaaag atagccggaa
    19501 tcatcgctaa aaatgatcct aagtaaggga tcaggttcaa aaaacccgca ataatcccca
    19561 acgtgacagc atactctaaa ccaatgaccg caaaaccaat cataaacatg attgccacag
    19621 caaaagccac agttagttgt cctcttatat aagaagaaac ttgactattc atttcactca
    19681 gcacattcaa cgtcggtttt tgcatgcgtg tcggtaaaaa tttgacaaaa taaggtgcta
    19741 attgtttacc gtctttcaat agataaaata agataaacgg catcgtcagc agagccacta
    19801 aaatagtcgc taccgcgccg acaaaacttc caagactctg aactgtactc ttagatatat
    19861 cttggatcat atcgcctgcc gaattcatga acttatcacc tgctgtttcc aactgttcgc
    19921 gaaattggtt gaacagcggg tcccgcaaaa tctcggttaa tttattatca atcgtatcta
    19981 catattgagg gaagttactg atgaagctca ctgtttgttc ctgaatctta gggatgatca
    20041 ctacgctccc ccatgcgatt agtgcaacaa ccaaaacaaa cagcccaatg atactgtaaa
    20101 gccttggtac ttttcgcttt tcaaagtaat caactaccgg attcatcaag taatacaaga
    20161 ttcctgctaa aatgataggc agacctacga ttgctaaaaa ttgccagatt ggtgcaaaca
    20221 aatatgaaac ttttgtaaat aaaaagacga tcagcaatat taacaataca acaagtaagg
    20281 ctgtgactac ttgattattt aaaaaccagc gccaaaacca cgataccggt ctgttcttct
    20341 tattttttcc ttccataatt cctcctgtta gttataaaaa atttggcttc ccaaaccaat
    20401 agcaggcagt ctatgcggat gaagatagat tccatttgca atttgtcctt cttctggaca
    20461 agcatcaaaa atcaatgata cgtgagctac tgtctctaaa ttcccattgg ccatcggacc
    20521 gacataatcg atcgtatata cctgatcatc aaaagcaatt gttccgcctg ctttcaaaga
    20581 aaaaggttcg tcttttgata cttcttgaat caccgaatat tttcgtaagg cagctgttgc
    20641 tgttttatcg aacaaaatca gcatgggttc ttccttgttt attgcttctg tcccaatttc
    20701 tgtaatcttt gcctgaatca ttgcactctc tcctttaatt gctttcaaaa acagtataac
    20761 acattctcat tctttagccg tgtggaataa ttatgtgata gaataaaaac gaaaactatt
    20821 tcattacaat taggaggaat cagctcatat gatcgaaaag ataattttag gaacctatac
    20881 gcgtcgcgaa agtaaaggaa tctatacgat cgaccttgat acagaaaaag aagaattagc
    20941 caacctttca ttagctgttg aagaaaatag ccctacctat gtagcaaaaa gtaaagctgg
    21001 caatctttac acagttacta gtgtggatgg attaggtggt gccggtgcgt acgataagga
    21061 ttttcatttt ttgaatgcgg taacagagtc tggcgctcct ttgtgttatg tagcggttga
    21121 tgaagcacgt caattactat acggggcgaa ctatcataaa ggtgaagtaa atgtctacca
    21181 tatattagga gatggcgaac tgaaagcagc agattcaata ttccatcaag aagcgacagg
    21241 tcctcataaa aaccaagatc atgcgcatgt ccactatacg gatctgactc ctgaccaacg
    21301 attagtcgta tgtgatcttg gtacagatcg tgtgtatact tatgatgtgt ccgaaaacgg
    21361 caaattgaat cttgtaacta ccttcactgc agagccagga acaggccctc gccatcttgt
    21421 ctttcatcca aatggacaat tcgcttattt atttggtgaa ttagacagca cagtccgcgt
    21481 gctttcttat aataaagaaa caggtgcttt tgaagaatta cagaaaatat cgaccttgcc
    21541 agaagaattc gacggtgaaa atggaggggc agctatccgc atttcaaatg atggcaagtt
    21601 cctttatgct tctaaccgag gacataactc gattgctgta ttcgcagttt ttgaagatgg
    21661 ttcccacatt caaaacaagc aaatcatctc aacagaaggg gattttcccc gcgatttcgc
    21721 actagatcca agcaataatt ttgtcgtgtg tgccaatcag aacaccgata atctgacatt
    21781 atatcgccgt catcctgaaa caggattact ggaattactg aaaaaagatg tctatgtacc
    21841 agaatgtgtc tgtgtttatt ttgatcgtta gtaagaaaag gagaatgaaa tgaatcagca
    21901 agacgtatta gacagactac gggaagaact aaatattcct ttctttgatg ggaaaatcga
    21961 agataaagag tatagcgaag aggaatatca gaaactcaaa gccgatttac agaactactt
    22021 tgaacaatat gtacagaatg tagaaaacta atcagctttc catactatct gaaaagaaca
    22081 tcaggacaag acttttccgt ctatcctgat gttcttttct acaaataaaa aaccgccgag
    22141 atggttagac tcgacggaaa aggagtattt actcgatttt gagtaagtac aaggttgttg
    22201 ttggttatag gtatgtcatt atcataaagg attttgatca ctctatcata aaggtaatat
    22261 tacatttata ttagataact ctagttttta ttgttatcaa agatttcttt tattttttca
    22321 acaacaaatt agtcattttt tggatggcag ctgtcaattg gtctgtcgct tggtcttgtt
    22381 ttgcttcaga tgtattgaat agatcttcat ctacccctga ttcaagatcg atactttgga
    22441 tcatttcttc acagcctgct acatatgaaa gataagcttt ttcaaaattt ttatgaatgc
    22501 ccattgcttt tgctggtgga cgcaaagtac tgactttctt aagcattgcc cgatattttt
    22561 ttgttccttc ttcaaataac aggatgatct cttcaagagt cgatttgtcc agttcacttg
    22621 tttttccttc atcaattgcg tttctgatca cttcatattt cggatgcatt ccttctccga
    22681 ttgcttctgt ttccttgacg atttgatcga tggactgcac ataatagcca atattcggta
    22741 acatgttcgt tttcctactt tctccattgt tgttattatt tattctactt gtttttatcc
    22801 tcaaatgaca agtacttgaa aaaatttaat ggtttctata cagctcgcca ttcttattcg
    22861 tgctcaaaga aaccatctgc taaactatat tgtttccctg cgacaatgtc atattggatc
    22921 aattgatatt cgtcgtaaat ctcttgttgc gagcgattga attgcgcttc tttataccac
    22981 tgtccgtttt gatagtacag ttctcgttca aacgccggaa gttcctgttc taatgataaa
    23041 agcagctgat aaaagccatt tgttgtctga ttcgtctgtt ccattagatt cgctgcaaaa
    23101 taaaacggac tggtgattgc atcgtgagtc gtttgctttt ctaattctcc tttactgtcg
    23161 aacataagaa attgtgtttc atgcaatgtt tgtttgtcat tttttgcttg gatcgtatct
    23221 gaatagatcc ctggaagatg atccccccaa aaaacaacta aagtccttct agaaagattc
    23281 ttcaattctt ccgtgaactg cttcagtgcc gtgctgctat aggaaatatc ttgcagataa
    23341 ttctctaagt caagtgtccc acttccatct gaagtttttg caggatagtc tagattatca
    23401 tactttccat cgtagggcat atgtgtctgc atcgtgacta aatgaatgaa ctgaggtgtt
    23461 ttttcttcct tgagaagtgt cattacttct ttgtaagctg actcatcaga aatatatgga
    23521 ttattctcta tcgtatccgt ataggtcatc gtacgctcgc tgatgaactg gtcaaatcct
    23581 aatgtctgat aaacatcctc tcttttatac atcgaagtat tgtatggatg gatcgctgtc
    23641 gtctggtatg attgtgcgtt taacgctgaa acgatagaag gaagctgatc catttttggt
    23701 acaagcatcg tgtaaggggt ggtgagttgc gcattaaata acgccataga aaaaccagtc
    23761 aatgcttcaa attcgatatt tgctgttcca ccgccatagt tttgagaaag catattgcca
    23821 ctatatgttt gatcagctac ttcataataa tctgccaatg gctcaccaga tacttctacg
    23881 ccgtttaatc gactaggatc tgagaaactt tcactcatca cgaacacgat gttcggcgac
    23941 tcttcctcta cagttttatt tttttcatcg gctagcttct ggtatttttc agtgatttct
    24001 ttgatctttt ctttcgaata tccttcaggt tcatccattg gttctacctt cagattgtac
    24061 aaaaacccac cgataaaacc agtgttatag tagttcattt tctggctgta aggtatccat
    24121 agtgccgttt tattatatgc ttttcgcaac aaattatcgg gattgttgaa attactgata
    24181 taccctagca gtccaattgc cacaagcagt gtcgttaatc ggatcaattg gaatcgcctt
    24241 ccttttttca ggcttcgaaa catgtaccag caaaacaatc ctatcacggt tcctgcggca
    24301 gctaagatca ctgtaaacag catagtgccg gtcatatctt tcagcaatcc gatttcagtg
    24361 atcatcttca aatcgtctgg ataaatcggt tcttgccgat aactcatttt catataattt
    24421 gcaaaaccta atacaccgat ggctacgaca tacgtaaggg aacctaaagg gacagatcct
    24481 gctagtgcaa tcagaaaaat aagaataatc agcaagacga gacaggctaa gaagaatttt
    24541 tccgtatgcc aagaaaaagc aaatttcaac gcaaggtcta cggatagatc attttgacac
    24601 cactgcaaaa ataaattact aaaaacaaca agaaaaaaga tactgatgat tgctgctgtt
    24661 ccttttaaaa tctttttctg tttggtcgaa agtctgctta tatatctttt caaatgcttg
    24721 ctccttcatt tctatcaata aaagaatgtt gcttctctta ttttagttgt acgaaattcg
    24781 aaagtaaaga acggaaagaa gaattaatga aatccaaata ttctctttct ttatggcctt
    24841 tctggtttct ttaataagcg gacctttcgt actccagaaa ttttttctag ctgttgtttc
    24901 acttgattga gctgttcaaa atcagtactg tctatgtcaa tcaatatgta gacatgctca
    24961 ttcttatggt tacgcgatat atctgcgatc gctagctcgt tctcattcag cagagaaaat
    25021 atctctgcta atatattggt tttcttttga taaaatatag tgaatcgaaa cggcgcttgg
    25081 aaaaacattc gtgcggatgg ataattgacc gcttctctaa ccgtaccgaa caaaagataa
    25141 tcttttaagg cttcaactgc caaacgtccg ctgtctgcca aagcttcctg agtcgatccc
    25201 cctagatgag gcaacataag tatacggtca ttttctaaga actcttcttc tggaaaatca
    25261 gtcaagtatt tagccagatg ttgtttttcc aatgcttgca taacagcata tttatcaaca
    25321 atttcacttc ttcctacatt gataagtaca gcatcttttt tcattttttc tatattcgcc
    25381 tgatcgatca atccttttgt atcttctgtc aacggcagca tgactacgat gtaatccgag
    25441 gtagaaagaa ctgtttctaa atctgcttgc cgaacataat ccaactgggc atcgcggata
    25501 gaataaccca agacatccat ccctaagcta tagcaactta gcgctacttt tgtgcctatc
    25561 gctccaagac caagaagacc gatggttttg ccttgcaatt ctcgtcccac ataagcactt
    25621 cttttgtttt ctgcctgttc taaaatatta ggacctgtta gtgtttgtac catacgactt
    25681 gcttcgatta tcggacggga agataagagc aaacagcaca aaacaagctc ttttactgca
    25741 ttagcattta cacctggtgt attcatgacg atcgtcccgt tttcagaagc tttttcaacg
    25801 ttgatcgtgt tcaccccaac accagctctt gaaattgcta gcaaatctgg tgtaagccat
    25861 tcatctttca ctttcgtact acgaataact attccttcgg ctggcaaatc atctattatt
    25921 ttgaaatatt ccccttgtaa cttttctatc tcttgttctg gaatagcatc aatcaaatga
    25981 acgtgataca taaaaccccc tccttactaa caagtatctc gaaatttctg caattagaca
    26041 actgtttacc atttgacttc ctagaagcaa aaagagcagt tagagcagag taggctgagt
    26101 gataaaaata aggctatgac aagttactgc cataagcctt attttcgaga gcaaaatatt
    26161 gagggtgaga tatcttgata aatggtgttc cgttagctga cattgataat aagactaaat
    26221 ttcaaaaaag ttgaaaagca aatttcgtca atctcttctt atttcttaaa actaagtggc
    26281 tttttcacaa cctcttttta tctaataacc actgtttcca actcaactaa ttttgcccac
    26341 gtttcaattt gatctgttgt tagatttagc gagacaacgg tatgatgacc gccacctgcc
    26401 tgaatccatg aatggacacc ttcatggaaa ttcggtttag ttttccataa cacacgtgca
    26461 acaggtaaat taggtgcttc agtcgttggt tcaaaggctt ctacttcatt gatcagcagt
    26521 ttataatgcg taccgaaatc tgccatcgat acgactaccc cttctcctgc tttcccatca
    26581 aatacaagac gcgccggatc ttctctatct cccattgata aaggagaaac aacgattctt
    26641 ggtttcgtcg cagcaagcgt cggatctact tccatcatat gggattccaa gattgcttct
    26701 tggccactag ctagctcgta agtataatct tccatgaatc ctgtatcttt ccctcgagcc
    26761 atgattttca gcaaccgatc aatcgctgca gttttccagt cgccttcccc agcaaaaccg
    26821 tatccttctg ccatcaaacg ttgtacagct agtccaggta gttgtttcat tccatacagg
    26881 tcttcaaaat tagtcgtaaa agcgttatag cctccttctt ctaagaaacg gcgaataccg
    26941 atttcctgct gagcttgtac ttttacatgt tcctcccatg tcttttcttc ataatcacca
    27001 tagtcgaagg tatacaattc cttgtactct tcaaataatt gatcgacttc ttcgtctgat
    27061 acgcgatcga ttacttgtac aagatctccg ataccaaaat aatcaacagt ccaaccaaat
    27121 tgaatctgtg cttccacttt gtctccttct gtgacaccca cgtttctcat gttgtcacca
    27181 aaacgagcca cttttattcc aaaactttca ttataggcta ctgcaacatc catccaatca
    27241 gcaatctctt tttggatctc aggtcgtttc cagtagccaa cgacgatttt attttgttta
    27301 tttaatcgag cattgatgaa cccatattcg cggtcaccat gagcggattg atttaaattc
    27361 atgaaatcca tatcgatcgt tttccaagga atgctttcgt tatattgcgt agctaaatga
    27421 agcaatggtt tttgtagaag ctttgtcccg cggatccaca tttttgctgg tgagaaagta
    27481 tgcatccaag tgatcacacc tgctacttct tctcgataat tgacctcttt catgattttt
    27541 gtgatcgtat cagcagtaac tgctaattct tgaaggcgga ttggataagg caattggcca
    27601 ttttcattca gttcatcgac catttcttgt gcatgtttct ttacttctcg cagtgcttct
    27661 tccccatata aatgctgtga tcctacaaca aaccaaaatt ctttttctcc aatattcaac
    27721 ataattagcc actcctttta tttgttttgt ccgtaatacg cattttttcc gtgttttcgt
    27781 aaataatgtt tatctaaaat ccgttgaggc agctcttctg aaaatgaatt gagctgtctg
    27841 gtaaataaat tcatcttgca tacttcatct agtacgactg cgttcattac cgcactttgc
    27901 gcatctttcc cccaagtaaa tggaccgtgt ccgtgtaaaa gtacccctgg aattgctaag
    27961 ggatcaattt tgcgttcttt gaatgtttct atgataactt ttcctgtttc atattcgtac
    28021 ccgctgtcga tttcctgttg tgtcaaaaat cgagcacaag gtaccgatcc ataaaaagta
    28081 tctgcatgcg tcgtccccat cgcaggaaca tccaatcctg cttgtgccca gatcgtcgcc
    28141 catgtcgagt gagtatggac gattcctccg atttgaggaa atgaacgata taaaacagca
    28201 tgagtaggcg tatccgaaga gggattgagt ttaccttcaa tgatatgatt gtccaagtcc
    28261 acaacgacca tgtcgtctgc tgtcatctct tcataactga ctccgctagg tttgataacg
    28321 aaatatcgtg tttcaggatc aaaagcgctc acatttcccc atgtatattt gacgagtccg
    28381 tgtttaggca agtcaagatt tgcttggtat acttcttctt tcagttgttc cagcattttc
    28441 tatcactcct ttttcttgca attgatgaat cgctgttttt tcaatgtcga tcccctcacg
    28501 gtaacgtctc ataaatatct gatagcctgc tatttcttct gctgaaggtg tgatggtgat
    28561 tccttggtct tgtccaaaca cgtcttctgc caagaagttt tctaaagact tcccatgtcg
    28621 atccatcata taggctgcta ataacgcgat tccccacgct ccaccttctc cggctgtgtc
    28681 catcactgta actggtgcct ccatagcaga tgctagaatc cgctgtccaa cttctggtgt
    28741 tttaaaaatc cccccatgcc ccactaaacg atcaatttgg acattctcag atttcaatat
    28801 atccattccg attctcattg caccaaaagc actggctaaa tggatccgca tgaaattcgc
    28861 taaatcaaaa cggctacctg gtgtacgtac aaataatggc cttccttcat ttactcctgt
    28921 aatgttttca ccggaaaaat aaccataaga aagtaatccc ccgcaatccg tatcgccttc
    28981 tagcgctttg ttgaataata ccgtgaataa tttatctctg cttatctcca tacccaaaga
    29041 attggtaaat tcttcaaaaa tactgaccca agcattgata tccgaagagc agttattcgt
    29101 atgaaccatg cctactagtt ctcctgaagg tgtagtgacc atgtcgattt ccggatggac
    29161 attttctagt tctttttcta atacgatcat agcgaaggcg gaagtaccag ccgaaatgtt
    29221 ccctgtccgt ttggctacac tgttcgtagc gaccataccg gttcctgcat ccccttctgg
    29281 cggacaaacc gggattcctg gtctcaaatt tcccgtaggg tcgatcagat aagcccctga
    29341 ttcgcttaac ttgccagctt cttctcctgc tactagaact ttaggcaaaa tgtgatccaa
    29401 gtcaatcgct acgtgcgctt tttcgattaa ctgaccaaaa atatttttca tttcttgatg
    29461 gtaggttttc gttgaaggat cgataggaaa catgcctgat gcatctccta cgcctagtac
    29521 tttctcacca gtaagctgcc aatggacata acctgcaagc gttgtcaaaa aattaatttc
    29581 tttcacatgt tcttctttat tcaaaataga ttgatacaaa tgagcgatac tccatctctg
    29641 cggaatattg tattgaaatt tttccgttaa tattcgttct gcttcttcag tgattgtatt
    29701 tcgccaagta cgaaatggta ctagtaactg ttccttgcta tcaaatgcta gataaccgtg
    29761 catcattgca ctgaacccaa tcgacccgat tgtcgtaaga ttctcgccat agatttcgaa
    29821 tacttctgct gccatttttc ggtaactgac gcgcagtcct ttccaaatat cttctaatga
    29881 ataggtccag ataccatttt ctagtttgtt ttcccactca taactaccag cggcaatagg
    29941 agtaaaagat gaatcaatca atacagcttt gatcctagtt gatccaaact caatccctaa
    30001 agatgtacga ccatctatga catctaacat actttgcgca tttacttcct tcataatgat
    30061 ttaactccct ccttctcgtc aaacctgatc aaaccgtctt tttagtagcg cttacaatga
    30121 ttattgtata cttttgtacg tacatgtcaa gcggttattt acaagaatac aataaaaaac
    30181 acttgttttg tacgtacata agttataaaa tgaaattgct tacaaaatct gatcaaccgc
    30241 cttctcgaaa ttctagaagg agagaatact tatgaaaaaa gaaaaaaaag tttcctcatc
    30301 gtttatttat ttttttggcg catttggcgg cattctattt ggatatgata ttggtgttat
    30361 gaccggcgcc ttaccttttt tacagcatga ttggggtttg gcaggtaaag cttctttgat
    30421 aggatggatc acgtcttcgg tcatgttagg tgcgatcctt ggcggctctt tatctggtct
    30481 tctttctgat aagcttggac gacgaaaaat gattcttctt tctgcactta tttttatggc
    30541 tggttctgtc ctttctgcat ctgcccctca caatggttct tattttctga ttgcagcaag
    30601 gattcttcta ggtttagctg ttggcgctgc atctgcccta gttcctgctt atatgtctga
    30661 aatggctcct gctagactaa ggggaagatt gtcagggatc aatcaagtga tgattgcttc
    30721 tggcatgctc ctttcctatg ttgcagatta tttgctaaaa gtgttgcctg aaacgatggc
    30781 ttggcgcgtg atgttagggc tcgctgctgt ccccgcgctg attttatttt tcggtgtttt
    30841 agctctacca gagtcaccgc gttttcttat gcaatctggc cgcttggaag aggcaaaaag
    30901 agtattgaac tatattcgga caccaaaaga agctgaacag gaattcgaac aaatccagct
    30961 gaatgtcaaa caagaaaaga caaccggaac ttcttggcat actttgtttt tagaaaaata
    31021 tcgttcctta gtcattgccg gtattggtgt agcagtattc cagcaatttc aaggagctaa
    31081 tgctattttt tactatattc cgctgatcgt agaaaaagcg actgggcatg cagcgagcga
    31141 tgcattgatg tggccgatca tccaaggaat cattttagtt gctggttctt tgctcttttt
    31201 ggttattgca gacaagttca atcggcgaac tttattgaaa ataggcggta gcgtgatggg
    31261 actttcattc atcctaccag ctgttttagg aactgtactg gatgctcata caaattcgtt
    31321 gttgattctc ttgtttttat gtatttatgt cgcattttat tcttgcacat gggctccact
    31381 gacatgggta atcataggcg aaatattccc actagctgtc cgcgggcgag catctggcct
    31441 agcctcttct tttaattgga ttggttcttt cctagttggc ttgctttttc ctgtgatgac
    31501 tgcttctatg tctcaagaaa tcgttttcgg catttttggg atcatctgct ttttaggggt
    31561 tttatttatt caagagatcg taccagaaac tcgtgggaaa tctttagagg aaatcgaaca
    31621 aagtgcatct aaaaaaactt atcctaaacg tatttctatc catcattctt aaagaggttg
    31681 tgacagaagt ggtcagcttc aagaaataag aaggaaccgc ttagtttcca gtcacaagga
    31741 acaatttcaa aaaacagctt ctcatgtttg atgaatattg tgacttgtga ccagttggta
    31801 ggagaacacc gtttagtgga gaggtggtga aagaaacgtt cagccttgag cgatgacaaa
    31861 agctctcaca aacattgcga cgagtaaccg taggagcaat aagaggcggt aaaaacccgt
    31921 ctcttatttt tcgttttctt tcactgtttc ccgttcaact agtacaggtt catagagaat
    31981 atttggctgt gcctgtcctt tttcaatcgt tgtgacgatc caccgtgcgg catcttgtcc
    32041 caacttttct tttggatgcg tcaatgttgt caatttttta ttccctaaat ggcttaaaga
    32101 agaatcgtct gttcctacga tcgataggtc atctggaata tgatagccat tttctgtcaa
    32161 cttatctagc attaaactag ctatttgatc gttatagcaa atgatgccat ctaaagcttg
    32221 ttcttctttc aaccgttgta ctgttttttc agcgattgtt tctcgtgttt ccgtggtgaa
    32281 agtaatgata tcttccgtca aaaaacgcac attatactgt tcacacgcgc tgataaaacc
    32341 tttcatcctg tattttcctt gaagatcgtc gatttttgtg atgaacaaca gacgctgatg
    32401 tccttttttt atcaaatatt ctgctgccat aaaaccgact ttcacatcat ctaaacaaat
    32461 ataagaggca tttaactctt cataagcagc attgatcatc accatcggaa tgccttgttc
    32521 tctcaaagca acataaagtg ctaagtttgg gttatactga ttacttttcg taggctcaac
    32581 gatcaaacca tctaccccat aagcaatcat tttcttcaaa cactctttct ccaattcgtg
    32641 atcgttattc gtactggcta aaagcaatga atacccagat tctcgtaatt cattttcgat
    32701 tcctcggata atcgacggaa aaatataatc agagagatat gtggtgatga caccgatcgt
    32761 ttttgttctg ttcaatggtg ttttttcttt cttatagctg tcatctacat atgtgcccga
    32821 ccctttttct ttacgcagat agccctcatt taccaacaca gcgattgctt gccgaatcgt
    32881 atgtctgctg acgtcatata tttcttgcag cttgaattct gagggaatgg ttgtatttac
    32941 ttcgtattcc tcacgaagga tcttttgttt tatctcttct gcaatatctt gatattttgc
    33001 catttgcctt gccccttttt atttgtacgt acatatatca taacgagtct gcaaggttta
    33061 ttcaagcaaa aatcaaggtt tcttgtgctc ataaggcata cggaacaggt tcaccaaatt
    33121 ctggaaatcc ttgctcattc cacgtaaagc attgcgcgtt cgcgtgccga ttaggattgt
    33181 ctaacggatc ccctttttgg ttcttctctg gtcgagcatg atagatcaaa atatcaaagc
    33241 acccgtcttc tgaaaccgta aacgagttgt gaccaggacc aaattgctta tttttttcag
    33301 aagaaacgaa tactggctcc gataatttat gccatgattc ttttaataaa agattcttgt
    33361 gctcatcagc ccacagcagg cccatggcat agttttcatc tgttgcacta ccagaatacg
    33421 taatgaatat tttcccattg cgagtaagga ctgctggacc ttcatttact gaaaaacccc
    33481 gtttttccca ttcatactca ggtatagaaa ggaggatctg cttccccttt aacgtccaag
    33541 gattatccat ttcggataga taaagattag aattcccagt aatttcagga tcttgttggg
    33601 cccacacata atatagcttt ccttgagaag agaaagttgt tccgtctaaa ctgaaagttt
    33661 cccttttcgt ttttatttgt cccttttcta tccaatctgt attcattgga tctatatgct
    33721 gattttcaag tacgaacatg cggtgatgat gagattcatc acgtatagtt ttatgattgc
    33781 ttgcagcaaa gtaaatatac cattttccat tgatataatg gacttcaggt gcccagatca
    33841 attcactcat cggtccttct tcatgagcct gccatacaat caggcttgca gcatgttcta
    33901 attcattcag tgactttgcc cttcttaatt caatcacttg gtagcctgga accgatcctg
    33961 taaaataata ataaccatct gtatgtttat atacccaagg atctgcccgt tgccgaacga
    34021 taggattatt ataaagtgtc ttcatcataa caaatttcct cacattttct ttattctaat
    34081 tacattccaa gagtattttt ctatccctac atttaattcg tcatgttttt ctattgaaaa
    34141 atagtttatt tcaggtttta ttttttctgg ttcttcacgt gtatttttgt ccaacagatc
    34201 gctactggtt aatgtgtagt gctctccttg atctagcaaa ttgaaatcat gttcaatcgt
    34261 tatcttttgt tgttcatttg tgcgattgat caagaaaata gtcagctgat tgccgttatc
    34321 tacgatcaca ctgtccacat aaggaacatt ttttatcttt tcacaatcat aaacagggca
    34381 aatgatttgt tgtttcaata cttgaccttt agcatatttc gataagtgtt gcatcacata
    34441 ataagttgga ttcctccatg cttgtccttt agcatctgtc agtattaaag gtattgtgtt
    34501 tactaacaat gattgacaac taatctttac gcgatctgcg tgtcgtaaaa tagccagccc
    34561 taatgaacca aataataatg tatcttccat agtaaagtaa caccaatcga tgggactacc
    34621 gacttcaaaa tccctatgtc ttttttccgg ttgggcatgt acattccatt catcaaacgc
    34681 tagatacatt gttttctcac ttctcaaata tccttttaca taatcacaag tagcaacgat
    34741 ttcttcaatt tgacgatcga atcgataagc ttttgcaagg tatgtcgctg tatcatcacg
    34801 ctcattttta ggaggtttag tcaagtcttc ttcatcatac ttatcaatat agttatgcaa
    34861 agctaaataa tctacattct cataagcttc ttctaatgcg atacgatccc attcagggta
    34921 cgatggtaaa cgtggcgtag agcttccaac taagattgtt tcaattgaat catccactaa
    34981 cttcatgact tttgaggctt catttgctaa cctaccatat tcataagcac tcttagcccc
    35041 cacttgccat ggaccgtcta gctcattccc taaacaccat aatttaacgc caaaaggctt
    35101 tttttgccca ttttttattc ttaaatcact ccagaaggtt ccttttggaa aattacaata
    35161 ttctactaaa ttttttgctt catcaattcc ttttgttcct aaattcaccg tgaatatcgg
    35221 tttcgcttgt acatgactga tccatttaaa aaattcgtgg agtccaaaag aatttggttc
    35281 tatacctcgc catgctaaat caattttttt tggtcgttgt tctttcctac ctacagtatc
    35341 cacccaatca taaccagatg taaagtttcc tccaggatag cgaatgacac ctaattctaa
    35401 ttcctttaca taagagagga catcttgtct aaacccgtca ccatcagctg tttcatggcc
    35461 cggttcataa atccctgtat agacgacact tcccatatgc tcaacaaatg agccaaacag
    35521 ccgagaactg atctctccta ccgtaaaatc ctctctgatt tttactttca cttcttcgtc
    35581 caacagcttt ccctaccttt catttcctat agtcaagata atagatacaa gtttccatac
    35641 gccaccagca aagataaaaa taaaaggagg gaaaagaaat atgagcagta caaatcctaa
    35701 taacaatacg caacaaagaa tatttctcaa aaaatcaaaa aatactttcc atgcactttg
    35761 ttcaaaaatt tgtaaaaatg tgatatcttt gttttcagaa atcacatata tccaggataa
    35821 aagaaacatg gaataaataa gtaaaactac atatccacta attgaaagta cgattgtctg
    35881 ttcttctaat aattgattaa caagaaaata aataatgatc gttaacagac taaggaacaa
    35941 gttcttacca aaatgttgct ttattccttg aaagaaaaaa taaatgatat ttcctgatcc
    36001 ctcacctttc cattgcgcca ttacataaaa aacagcacat gtagcaggca cgatagtaat
    36061 aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag aaaccacaat
    36121 caactgtcca taaaatttag tctcaactat tttcatcttc ctcactcttt cattccagac
    36181 atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag taatggcagc
    36241 attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg ccctgtaaat
    36301 aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat caatggataa
    36361 agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag agtaggtttg
    36421 ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc aatgcgtgct
    36481 gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa gataccaaat
    36541 gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc aagcaaattg
    36601 acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt cagcaaaacg
    36661 aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata ccccgcaaga
    36721 gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt atttttgatg
    36781 taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt atagctatct
    36841 gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga agaaataatc
    36901 agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat cgttcgaatg
    36961 atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga gctttctggt
    37021 gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt acacattagt
    37081 ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg atgcatagcc
    37141 caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg tttctgtctt
    37201 aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca tcgaaccaat
    37261 cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg taatgttaaa
    37321 aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag agggagagat
    37381 tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc aaacagtcat
    37441 gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga tcggcaagcc
    37501 gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca tagaaaaaat
    37561 aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac gacaaaaacg
    37621 attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga taatttgtgt
    37681 tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg ctcgttcatc
    37741 actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa agaaaatatt
    37801 caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa ataataataa
    37861 aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat tccaatattt
    37921 ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata caatcttggt
    37981 ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat aacacctatc
    38041 tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta tcctgtataa
    38101 agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt tcatgagtgt
    38161 ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat cgttattgat
    38221 cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt gtttcgataa
    38281 ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat ccaagtaggc
    38341 aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc aatatttcaa
    38401 aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg catatcctac
    38461 gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg tagtcacatt
    38521 ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga tttcaatggc
    38581 tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt ctggaccagt
    38641 cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct caggagacgc
    38701 aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta acatccagtt
    38761 atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt tactactatc
    38821 agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt gttcagtatc
    38881 taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt gtacctgcat
    38941 ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt ctttaaaatc
    39001 agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg ctccgttttc
    39061 tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt ttttagaaga
    39121 aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca tttcaatttt
    39181 gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata tttcaccatc
    39241 agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat cagattctgc
    39301 tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca aagagccaat
    39361 taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga catctgacca
    39421 cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct tttacatttg
    39481 ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt gtatcaaatc
    39541 cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag tgaacagtta
    39601 gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg tcatttatta
    39661 cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag tttgctgaac
    39721 gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata aatggataat
    39781 agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca ataacgttta
    39841 ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa gtgattaata
    39901 gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa ggaggagcaa
    39961 tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata ttccattcat
    40021 caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta tcgcacatcg
    40081 ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa tgagaaagat
    40141 catttttttg gttgccataa tattgatgca gagacaaata atctatttga tcgtacgctt
    40201 gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc gaacttccgc
    40261 ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt tcctctgcta
    40321 accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc atttcattcc
    40381 ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc cttaaatcac
    40441 tccaataagt tcctttagga aaattacaat attcgactaa attacgagct gcatctactc
    40501 cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga caccagttat
    40561 aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa tccaaccttc
    40621 taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac acaaaatttc
    40681 caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg acgtcttggc
    40741 gaaatccact tttattagct gatggatgat ctggctgata aatcccttca tatactgctc
    40801 gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct acacgcttga
    40861 cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata catgaataat
    40921 acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt ttttatcgat
    40981 tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa cttttattaa
    41041 caaatatgtt aatatataag aaaaaccttt taagaggtga tatatatgca actacaaata
    41101 aacgaagaat ccttaccggt atatgaagca ttagctagta aaacaaggat caagatcatc
    41161 cagctacttt ccaaaaaaaa gatgaatgtc aaagatttgg caaaagaact tggagtgagc
    41221 agtgctatca cgacgatgca cgtgaaaaag ctagaggaag caaacatcat caaaacagaa
    41281 aaagtaggac aacaaaaaat ttcgagcctt cgtgtcgata aaatcgatat tagttttcca
    41341 gaaaaaatat tcaatgcttt tgatacgaaa gaaacatcga tacctattgg tcactataca
    41401 aattatgcaa ttgaaccaac atgcggttta gctacgatcc atgattttat cgggaaagtg
    41461 gatgaaccac gctattttat ggatcctcga aggatggatg cccgcattct ctggtttacc
    41521 agcggatttg tcgagtatca ggcacctaat tttttaaata cagaggatac attggagatg
    41581 ttggaagttt ctgtggaaat ttcttctgaa tttccttttt caaatgacaa ttggccttca
    41641 gatatcactt tcagcctaaa tggtgtggag ctaggaacat ggacgagccc tggagatttt
    41701 gctgatatcc gcggtaaata tacgcctgat tggtatccag ataatcttaa tcaatacggc
    41761 ttgctgaaga cgatccgaat taccaaacac ttgacgaata tgaatggaga acccttgtca
    41821 aacatcacga tcaacgacat ccctaaagag caagacactt ggcatttgcg aatcgaagtg
    41881 aaagacgatg ccaaacatgt ggggggctgt actttatttg gtaaaggatt cggtaattac
    41941 gatcaggata tcaaattaaa agtttactac agctgatatt tttcttttct attttataaa
    42001 acaaaaacag ccaatcccta tgaagggacg gctgtttttg ctttattgtt atttccagaa
    42061 atcatccaaa acggaaattg gcaaatgtcg tttatgttgt gtcttgttcc accatgcttc
    42121 gattttttct tgtgcttgag cgggaacttc ttttccttct agataatcat caatttcatt
    42181 atatgtgaca cctagtgcga cttcatctgc aatcattggt ttcccatctt caagatctgc
    42241 agtcggaatt tttgtgtata atttttccgg tgcattcaat gcttgaagca attgtttccc
    42301 ttgtcgtttg tccaaacgga ataatggcaa aatgtcggct ccaccatcac caaatttcgt
    42361 gaagaatcca gtaatgtttt ctgcagcatg atctgtccct aatacggctc ctgctctttc
    42421 tccagctacg gcatattgcg taatcatacg ttgacgtgct ttgatatttc ctttgttaaa
    42481 atcgctgatt cccacacctg cttcgcttaa tacttgtact tgtgcatcaa cagctggttt
    42541 gatatttact cgcagactaa catcgggctg gataaagtca agagcagctt ttgcatcttc
    42601 ttcatctgct tgttcaccat aaggaagacg aacagcgata aattgatagt tttcatcttt
    42661 tgtttcttca cgcatttctt ccatcgttag ttgcgccaaa cggcctgcta aagtagaatc
    42721 ttggccgccg ctgataccta gtacaaaagt tttaagaaac ggatattttt tcaaatatgc
    42781 tttcataaag tcaatacttt tacgtatttc ttcttttgga tcaattgttg gtttgacacc
    42841 taattcattg ataatttctg tctgcaggct catttattct cctcctatgc ttctgtatga
    42901 agttctgcta cgcttttttt cattcgttcc atgatagcca ttttatggtt ccagcattca
    42961 gtagacagat cgactgggta tttttgcgga ttcaagtctc gtttatactc ttcccatagt
    43021 gaatctagat tttcttttgt atattctttg atttcgttta gtgcaggtaa ttcgtaaact
    43081 ctttttcctt cgataaagat atcttgtaaa actgggcgag ctgtaaagtc tcgaacagtt
    43141 ttattgataa acgtatgcac tggatggaac atgaagatag cttcttcttc tcgagggtct
    43201 tcatcccata atgtcacgta gtctccttca gatttcccat caaaatttcg agtgatgcgc
    43261 cacacttgtt ttttccctgg agtagttact ttttctgcat tgcttgataa cttgatcgta
    43321 tccatcattt ttccttcatc atcttcgatc gatactagct tgaatactgc accaagggct
    43381 ggctgatcat aggctgtgat caattttgtc ccaacacccc atacatcaat tttagctttt
    43441 tgcatcttta aattcaaaat cgttgcttca tccaagtcat tcgaagcata gatttttgct
    43501 tccgtaaatc cggctgcatc taattgttcc cgaacacgct tagatatata ggccatatct
    43561 ccactgtcga tgcgtacgcc ttggaagttg attttgtcac ctaattcttt cgccacgcga
    43621 atcgcacttg gcacacctga tttcaacgta tcataagtgt cgactaagaa cacgcagtct
    43681 ttatgggttt tagcgtaggc cataaatgct tcataatcat ttccataaga ttggactaac
    43741 gaatgagcat gggtcccgct agctggtatc ccaaatatct tcccagcacg tacattgctt
    43801 gttgcatctg ctccgccgat atatgccgct ctagttcccc agactgctgc atccagttct
    43861 tgtgcccgtc tagttccaaa ttccaatagt ggatcttctc cgatgacaga tttgatacga
    43921 gctgcttttg tcgcgatcaa cgtttggaaa ttgaccatat tcaacagtgc tgtttctact
    43981 aattggcagt gcgctaaagg cccttccact tggatcaatg gttcatttgc aaaaactagt
    44041 tctccttcac gagcagaacg aactgttgct ttaaattcaa aattttgtaa atactccaaa
    44101 aaaccttcag gatagacttc taatccacgc aagtaagcaa tatcggaatc attgaacgtc
    44161 agattctcta aataattgac taaccgttcc aatcctgcaa aaaccgcgta tccgtggtta
    44221 aaaggcattt ctcgaaagta acattcaaaa acagcatgta aatcagctcg acctaattcc
    44281 cagtatgtct gcatcatatt gatttgatat agatccgtat gcagcgtcaa actgtcgtct
    44341 gggtaagtat tattcatctt gtattactcc tcttggcaag ttttcatttc ctacccatta
    44401 taacaaaaaa aattaatagg aaaagaaatc ttccattttt tctgaaaaag cacatgtttt
    44461 acggatattt cttgctaaaa atgaactcca tctgctaaaa ctatcctttc ttattggtat
    44521 ttaacctaaa cgagaaagaa tacttatttt attcaatgta tccgagacac gaagaaatta
    44581 gcgttttcta tttttcttac ttgataaaat aagtagattt tcctactaca atcgtagccg
    44641 ttaagatacc gatgattgaa caaatataac caaatgtctc tacaacataa tcaatggcaa
    44701 aagtttttga agcaataata cgtctttcct tttttgcttc ttatccccaa agaaacggat
    44761 ataacttatt atgtattgaa tttttttgga aaggcgaatt atgacaagat ataccttgcg
    44821 ttgaaaaaac tcgcggaaaa aatatcacac gtttttaaaa agatacaaag taagaaagca
    44881 gctgtcaata gaatggaaac aaaaatggcg agacatcaat cagtctcgcc ttgtttttta
    44941 ttgtatacat tagatatgga gcaggttacc ataaagatga ttattagtcg ttattaaata
    45001 gaatccttcg tatttttttg ttctatcact acaatatctt tatttggacg tttgaattgt
    45061 attccggcac gttctagctc ctgtttcact cctacatgga ctttgacatc ttctcgtgtc
    45121 atttttaaaa cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt tttcttcgta
    45181 ttgatcatca cgacttgctt tttatcatat gtgtctacca atagcagttg tgttcgatct
    45241 aacgaaaata atttgtaata attaatagcc gtattcccaa aaaagaattc cactacttta
    45301 ggataaaatg tcttaatatt taaattacta ttcacaggtg tttcgattag cttcatctca
    45361 ttcctctttt ctatatagtc gatttagatc caatcttaag ttatgttacc atctttccta
    45421 gcattaagga atcggttaca attgaacctt taaagacaaa aggatttacc ttttatcact
    45481 taatagtata acataatttc atgagaaaaa aatacaattt tttcttgacc atctcgttac
    45541 gtaaaggatt atgcttacat ttgtcaggag gaaaaataat ggagtacaca ataaagaaaa
    45601 tgtcagagat atcaggagtc agtccgagaa ccttgcgctt ttatgatgag attggactgc
    45661 taaaaccagc taggatcaat tcttcaggtt atcggattta tggcaaaaaa gaagtcgatc
    45721 gtctgcaaca catcttattt tatcgaacaa tggcattcaa gttggatgat atccaagagg
    45781 tcttagacaa tccatctttt gaccaccaga aagctttaat caagcatcag caaatgttgc
    45841 tggaaaaacg ggcacaaatc gataccctct tgacaactgt ccaacagaca cttgatatgt
    45901 acgaaggagg aagaaaaatg agtgacaaag aaaaatttga agggtttaaa caacaaaagt
    45961 tgaaagaaaa tgaagaatcc tatggacaag agattcgaca aaaatacgga aaaaaaaagg
    46021 ttacagcatc caatgaaaaa tggatgaata tggataaaga aacgtatgaa gaaatgcaaa
    46081 ctgttgaaaa gcagatgtta tttgatctca ctctttactt aaaagaacca gaagatgaaa
    46141 gcttagcaga ccgtatcttc caagctcata agaagtggtt atcttacagc tggcctgaat
    46201 atcagccaaa agcgcataaa ggactaggaa tgatgtacga agccgatgaa cggttcactg
    46261 catattatga cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa attatccaaa
    46321 aaaaggcgta atcttttaca tgatccaaca aaaaagtaca cgtaaaatga cctaataaca
    46381 aaacagcaga cacccaagtt agatttttat gctaactttt ggtgtctgct ccattctttc
    46441 acaagttttt tcatcctact ttaaatatat tcatcgttga ataaacgtat aaggtatttt
    46501 cactttatcc tttttttctg taagaaacaa ttgaaatgcc atttctccgc aagcttccag
    46561 atggtggtcg atggttggga aaccaagaag ctcgctgatc agcaaattat cgcgtccaat
    46621 caccactggt gtcttatctt gcagatagct ttgcaagatg cctgctgcaa ccatatccga
    46681 atttgtaaag acaccatcaa ctccaagctc tttaaaaaag aagcctgctt gttttccttt
    46741 ctctgcatct atacaatccc aaaaaacaag tgattcatca aaagatggaa aaagttgatg
    46801 acatagctgc aaagtgattt ttgagttata acttagcctg ccacttcgcc ccaacgtgat
    46861 gcccaattgc tttatacctt gctgcttcaa ataagtaaga ccttctgtaa ttgattgttc
    46921 tcgatcaata aagacacagc ttgcctgttt tcccttgatt tcttcacaaa aaactagagg
    46981 tccatatttt tgatatgcca ataaatcatc tagtgtattg gcacgagacg taatgatcaa
    47041 tccatcgaaa gctttagctg caaattcttc aagatacctt cgctcttttt ctttctgata
    47101 gcccgtcggt aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa tgatcccact
    47161 gatcaactga tcaaaatacg gatgattggt ataaggcaga atcactccaa tgcttttcgt
    47221 ttttccataa cttaactgtc tggcatttgc attagggata taatcgactt ctttcatgac
    47281 cgcaagtatt tctttccttt tttcctcatc tacatatgga tgtccattga ttacacgtga
    47341 aatagtagaa actgaataac ctgtgagctt tgcgatatct cgaatgtttg ccactgctgc
    47401 ttcgccacct atacaaaaag attttcttgt aaatagtcta ccacagctgg accgcattca
    47461 aaaaactgat acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc ccaatatata
    47521 tcttttgtca aattttcgat ttcattcatt ggtatttctt ttactatatt cctattcaac
    47581 ccttgaaaac tgtacaacgt taatacggat cccttgaact cgacaaacgc ataaaaataa
    47641 ttgttcgttg tgccatctgt tatctctaca taagtattca ttgcaagccc tccttttgat
    47701 actttgagta tagtgtatga aacgcgtctc atagcaagga gtttgttttg ccaaagaaaa
    47761 gttttattcc tctttcatta ttaccaaagt ctcttatttt aaattgaata cattataatg
    47821 atactgtaaa tatatcttta ttattagtga atggatattt acttttaata gataaaaaat
    47881 tataactatt aaaaataact attttcatta taattacaca
//
LOCUS       DAXLPQ010000016        47470 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.016, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000016 DAXLPQ010000000
VERSION     DAXLPQ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.016"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(55..789)
                     /locus_tag="ACF3UO_001127"
     CDS             complement(55..789)
                     /locus_tag="ACF3UO_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD3657168.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1116..1526
                     /locus_tag="ACF3UO_001128"
     CDS             1116..1526
                     /locus_tag="ACF3UO_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFD3657169.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1519..2220
                     /locus_tag="ACF3UO_001129"
     CDS             1519..2220
                     /locus_tag="ACF3UO_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFD3657170.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2220..3806
                     /locus_tag="ACF3UO_001130"
     CDS             2220..3806
                     /locus_tag="ACF3UO_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657171.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3825..4046
                     /locus_tag="ACF3UO_001131"
     CDS             3825..4046
                     /locus_tag="ACF3UO_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFD3657172.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4043..4804
                     /locus_tag="ACF3UO_001132"
     CDS             4043..4804
                     /locus_tag="ACF3UO_001132"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFD3657173.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5184..5693
                     /locus_tag="ACF3UO_001133"
     CDS             5184..5693
                     /locus_tag="ACF3UO_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFD3657174.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5768..6307)
                     /locus_tag="ACF3UO_001134"
     CDS             complement(5768..6307)
                     /locus_tag="ACF3UO_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFD3657175.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACF3UO_001135"
     CDS             complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACF3UO_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFD3657176.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7320..8171
                     /locus_tag="ACF3UO_001136"
     CDS             7320..8171
                     /locus_tag="ACF3UO_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFD3657177.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8199..8834
                     /locus_tag="ACF3UO_001137"
     CDS             8199..8834
                     /locus_tag="ACF3UO_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFD3657178.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8854..9627
                     /locus_tag="ACF3UO_001138"
     CDS             8854..9627
                     /locus_tag="ACF3UO_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3657179.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10035..10832
                     /locus_tag="ACF3UO_001139"
     CDS             10035..10832
                     /locus_tag="ACF3UO_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFD3657180.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10810..11223
                     /locus_tag="ACF3UO_001140"
     CDS             10810..11223
                     /locus_tag="ACF3UO_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3657181.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11207..13852
                     /gene="mutS"
                     /locus_tag="ACF3UO_001141"
     CDS             11207..13852
                     /gene="mutS"
                     /locus_tag="ACF3UO_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFD3657182.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13870..15978
                     /gene="mutL"
                     /locus_tag="ACF3UO_001142"
     CDS             13870..15978
                     /gene="mutL"
                     /locus_tag="ACF3UO_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFD3657183.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16000..16560
                     /locus_tag="ACF3UO_001143"
     CDS             16000..16560
                     /locus_tag="ACF3UO_001143"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFD3657184.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACF3UO_001144"
     CDS             complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACF3UO_001144"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFD3657185.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18856..19569
                     /gene="treR"
                     /locus_tag="ACF3UO_001145"
     CDS             18856..19569
                     /gene="treR"
                     /locus_tag="ACF3UO_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFD3657186.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19646..20092
                     /gene="msrB"
                     /locus_tag="ACF3UO_001146"
     CDS             19646..20092
                     /gene="msrB"
                     /locus_tag="ACF3UO_001146"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFD3657187.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="ACF3UO_001147"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="ACF3UO_001147"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFD3657188.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="ACF3UO_001148"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="ACF3UO_001148"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFD3657189.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="ACF3UO_001149"
     CDS             21907..22485
                     /locus_tag="ACF3UO_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3657190.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="ACF3UO_001150"
     CDS             22537..23019
                     /locus_tag="ACF3UO_001150"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFD3657191.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="ACF3UO_001151"
     CDS             23136..23510
                     /locus_tag="ACF3UO_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657192.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACF3UO_001152"
     CDS             complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACF3UO_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFD3657193.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25687..26277
                     /locus_tag="ACF3UO_001153"
     CDS             25687..26277
                     /locus_tag="ACF3UO_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFD3657194.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26405..27754)
                     /locus_tag="ACF3UO_001154"
     CDS             complement(26405..27754)
                     /locus_tag="ACF3UO_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3657195.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27922..28662)
                     /locus_tag="ACF3UO_001155"
     CDS             complement(27922..28662)
                     /locus_tag="ACF3UO_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3657196.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28675..30267)
                     /locus_tag="ACF3UO_001156"
     CDS             complement(28675..30267)
                     /locus_tag="ACF3UO_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3657197.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     regulatory      complement(30405..30579)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(30835..31131)
                     /locus_tag="ACF3UO_001157"
     CDS             complement(30835..31131)
                     /locus_tag="ACF3UO_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657198.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31307..32032
                     /locus_tag="ACF3UO_001158"
     CDS             31307..32032
                     /locus_tag="ACF3UO_001158"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFD3657199.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32025..32867
                     /locus_tag="ACF3UO_001159"
     CDS             32025..32867
                     /locus_tag="ACF3UO_001159"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFD3657200.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32870..33391
                     /locus_tag="ACF3UO_001160"
     CDS             32870..33391
                     /locus_tag="ACF3UO_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFD3657201.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACF3UO_001161"
     CDS             complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACF3UO_001161"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD3657202.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34458..34727
                     /gene="rpsO"
                     /locus_tag="ACF3UO_001162"
     CDS             34458..34727
                     /gene="rpsO"
                     /locus_tag="ACF3UO_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFD3657203.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34915..37041
                     /gene="pnp"
                     /locus_tag="ACF3UO_001163"
     CDS             34915..37041
                     /gene="pnp"
                     /locus_tag="ACF3UO_001163"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFD3657204.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37551..37817
                     /locus_tag="ACF3UO_001164"
     CDS             37551..37817
                     /locus_tag="ACF3UO_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3657205.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37961..39952
                     /locus_tag="ACF3UO_001165"
     CDS             37961..39952
                     /locus_tag="ACF3UO_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFD3657206.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40306..41607
                     /locus_tag="ACF3UO_001166"
     CDS             40306..41607
                     /locus_tag="ACF3UO_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFD3657207.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41737..43107)
                     /locus_tag="ACF3UO_001167"
     CDS             complement(41737..43107)
                     /locus_tag="ACF3UO_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFD3657208.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43289..43612)
                     /locus_tag="ACF3UO_001168"
     CDS             complement(43289..43612)
                     /locus_tag="ACF3UO_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFD3657209.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43937..44545)
                     /locus_tag="ACF3UO_001169"
     CDS             complement(43937..44545)
                     /locus_tag="ACF3UO_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFD3657210.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44875..45591
                     /locus_tag="ACF3UO_001170"
     CDS             44875..45591
                     /locus_tag="ACF3UO_001170"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFD3657211.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45604..46299
                     /locus_tag="ACF3UO_001171"
     CDS             45604..46299
                     /locus_tag="ACF3UO_001171"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFD3657212.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46383..47012
                     /gene="udk"
                     /locus_tag="ACF3UO_001172"
     CDS             46383..47012
                     /gene="udk"
                     /locus_tag="ACF3UO_001172"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFD3657213.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8788 c         9878 g        13413 t
ORIGIN      
        1 ataaaaaaac ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc
       61 cataaataat aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac
      121 tggtacccat gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg
      181 tacaagacgt ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag
      241 tgaagcaact aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc
      301 ttggaagaat ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa
      361 gaattcattg acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc
      421 taacacatgg tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat
      481 caattgtcca atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca
      541 agggaataga ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct
      601 gattccacca aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag
      661 catccagtca ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt
      721 acctagaacg attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga
      781 gtaatccata aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg
      841 aaaagcatcg gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat
      901 aaaaaaatga attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt
      961 taaaagttct ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt
     1021 tttctcaaaa attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta
     1081 gtaaaatgaa agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca
     1141 ttattatttt cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc
     1201 ctggaagtat cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc
     1261 ctgaaaaaat cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc
     1321 ctgctggtgt aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac
     1381 tgggagcagt cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag
     1441 gtgtagaagc tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg
     1501 aaatggagga gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg
     1561 actttaggag tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg
     1621 aatcctctcg tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc
     1681 tataaagact ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg
     1741 gcacttgcca tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta
     1801 atggctgcga ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac
     1861 ttcttctctc ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct
     1921 atttctgtcg atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt
     1981 gtctctacag gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc
     2041 gaaagtccag ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca
     2101 aaagcaatcg agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac
     2161 ggaatattga ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga
     2221 tgcgaaaacc actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga
     2281 aagacgtgta tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga
     2341 ttctcctcct agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag
     2401 ttgttcagct ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc
     2461 agcagtttag cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact
     2521 tttatgatac gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta
     2581 cgctgaaatt ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat
     2641 ttgcgcaaaa gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac
     2701 agcaactgca aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag
     2761 aagaaatcat tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct
     2821 ggccatttga aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt
     2881 tttttaatgt tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct
     2941 tttttttaag aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga
     3001 tttctgacaa tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt
     3061 attttcaagt agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat
     3121 attatagtga tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac
     3181 cgccctttac agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg
     3241 ggctgccagc agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt
     3301 tcgcctatct ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta
     3361 atcatttagt tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta
     3421 gacacaaaca tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc
     3481 tgactgtgtt taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt
     3541 taatgacaga tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt
     3601 tccgtaatga gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc
     3661 ttctgatttc gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg
     3721 tgactgaaga actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc
     3781 aaaaacaaaa actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa
     3841 ttttaccaga attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac
     3901 tttatgttgt tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat
     3961 tgatcaaaac aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag
     4021 cagatgattg ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt
     4081 atttatcaca ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca
     4141 agatgctttt gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg
     4201 atttcctgaa acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca
     4261 agcggtatcg aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg
     4321 gatattggat gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta
     4381 tgagacgaat gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg
     4441 ccaaaaaagc ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg
     4501 tgggatcgct tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct
     4561 ggattacgca ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc
     4621 aatgaatgcg gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac
     4681 accagtcaag cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc
     4741 tcctcaagca agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa
     4801 ataaccttgt gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg
     4861 atgataaaaa aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa
     4921 ttctttttaa taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa
     4981 acgatattca aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag
     5041 ctatttttat ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc
     5101 gacacttcag ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt
     5161 atcttgcaaa ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga
     5221 caacgacaga tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg
     5281 ttttgtctgt ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc
     5341 tgtccttgta taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata
     5401 ttgcttctcc tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat
     5461 tgcttatcaa ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga
     5521 cagcatgcgt atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc
     5581 aactaccttt tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg
     5641 tcggtgggat aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg
     5701 tttaatttaa aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct
     5761 tttttgatta atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat
     5821 aagctgctcc agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa
     5881 atgcagttgt aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg
     5941 cagcaagaga gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt
     6001 cgatcatcca accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg
     6061 gcccaaataa aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc
     6121 caagtaaaag ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg
     6181 ttaatccaat agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct
     6241 gagaaaggac agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc
     6301 ggttcataac gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa
     6361 acaaagtgat tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc
     6421 ggtctttttc aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga
     6481 gcttcgtcga tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc
     6541 aatttttcag cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct
     6601 tttactgtta cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg
     6661 tggtatgaag ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat
     6721 tgacgtgctt gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt
     6781 tgttctagta agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt
     6841 acgaacaagt tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt
     6901 tcagttaatt gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct
     6961 ggtgcgtaag ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga
     7021 cgagaaattt tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat
     7081 aagtttttgg agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat
     7141 cttcaccttt gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat
     7201 gagttattat ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca
     7261 cgaatgtcaa gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa
     7321 tgagagggta tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc
     7381 cggtatcacc attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg
     7441 aaaacagctt ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag
     7501 gaacggctgt ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa
     7561 agattttata cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg
     7621 aattaggaac atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt
     7681 taagtaaggc agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat
     7741 tatgtggatt tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta
     7801 tgttagaatc aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga
     7861 tgtttgcgaa tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg
     7921 tcggaaaagt gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac
     7981 acgtgatagc gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg
     8041 atggaatgac agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata
     8101 ttggtggcgg tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct
     8161 atgtggacta aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa
     8221 aaaatgagga aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg
     8281 gagtacctaa gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt
     8341 tatctatttc tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt
     8401 atcagtatgt agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact
     8461 tagtcgtatt gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga
     8521 gaaaagtata cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat
     8581 tgtttgaaaa aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt
     8641 ataaacagca aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa
     8701 aggaattctt tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg
     8761 ccgattgggt aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa
     8821 gtaagtattt ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat
     8881 attgatggaa cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg
     8941 gaaaaattac gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat
     9001 gcgcaagaga tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc
     9061 ggttttttag accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg
     9121 ttcgttcaag aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc
     9181 aagcgttctt cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct
     9241 gtcttgcctg aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca
     9301 tttttcgatc aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc
     9361 tggcatgaga acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg
     9421 cacttagcag aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa
     9481 aacgaccgtg aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca
     9541 gaagtacaag cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag
     9601 gcattgaaag agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt
     9661 aataagccca gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc
     9721 gcagatgcaa gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc
     9781 aagaaataag aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat
     9841 ttctgaagaa gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg
     9901 tcatagtccc atttttttat tttatttttc aaaactaaga aataccagga aagagttcct
     9961 tttgtttgac cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag
    10021 aagaggaatt tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag
    10081 agatgattac tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg
    10141 taaatggtga gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt
    10201 tgcaagacgg cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct
    10261 ttgagtttgt aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc
    10321 ctggacaagg gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc
    10381 aggctcgttc ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag
    10441 aagaagccag aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg
    10501 aaaaacaagc aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata
    10561 cacacgttca gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg
    10621 ttgggatgac aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa
    10681 agtttctgac tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa
    10741 gcggctgtat cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc
    10801 agatcaacga tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag
    10861 ccggaaattc aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc
    10921 attcgctaca aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga
    10981 gaaaaaatca aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca
    11041 gcagaaaaag aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg
    11101 cttgttgtag cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca
    11161 actatgatac aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac
    11221 taaaaatact cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt
    11281 tttgttctat cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc
    11341 acagcttttg gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat
    11401 gtgcggtgta cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta
    11461 taaagtagcg atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg
    11521 cgaagtgatc cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa
    11581 agacaacaat tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc
    11641 cgatttaagt acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa
    11701 tgaagcctct gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct
    11761 tcgtgaacag ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga
    11821 aaacgcggaa tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac
    11881 cggcaaacta ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa
    11941 agcagtagaa taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct
    12001 agaattaagc caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga
    12061 tgaaacaaaa acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat
    12121 ccaggcaaaa caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt
    12181 tgaacgtatc gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg
    12241 tcgagtagct ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga
    12301 acaagtgcca atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct
    12361 gctttcagaa atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga
    12421 tgatccgccg ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct
    12481 cgatatgtac cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa
    12541 agagcgtcaa gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta
    12601 ttatatagaa attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa
    12661 acaaacttta gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca
    12721 aatcctcgaa gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag
    12781 agaagaagtc aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt
    12841 agatgtgcta caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact
    12901 tgtcagtgac aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt
    12961 attaggacat caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt
    13021 gctgattaca ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac
    13081 tgttctgatg gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt
    13141 tgatcggatt tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt
    13201 tatggtagag atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat
    13261 tttgtttgac gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc
    13321 aatcatcgaa tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca
    13381 tgaactgacg gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt
    13441 tgaaaaagac ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag
    13501 ctacggcata catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc
    13561 agatatcctg catacgctag aaaatggcga taacggacac catactgttc cagctgaagt
    13621 agaagagaaa actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa
    13681 tcaagaccat atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga
    13741 attatccgaa aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat
    13801 gacgccaatg gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg
    13861 cggatatcga tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg
    13921 ggagaagtag tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac
    13981 gccggcagta ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg
    14041 attgataacg gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg
    14101 acaagtaaga tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg
    14161 gaagctttgc caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa
    14221 gaaaaacaag gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca
    14281 ccactgcgtc aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc
    14341 ttgaaatacg tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga
    14401 ctggcattga gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg
    14461 gcaactgctg gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc
    14521 gcaaaaaaaa tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt
    14581 tcattgcctg aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt
    14641 tttatcaaga acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg
    14701 gtcggtcgtt tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta
    14761 aatgttcatc cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta
    14821 attagtaacg ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat
    14881 aatctacggt ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat
    14941 ttgtcctacg cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga
    15001 gagacaggta cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat
    15061 aagtctgtgg aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca
    15121 gaaaaaacag cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa
    15181 acagtggaaa aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat
    15241 gaagaacaag cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca
    15301 ctccatcctg aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag
    15361 aaattagaaa cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg
    15421 cacggaacgt atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct
    15481 gcccaagagc gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat
    15541 ctgcaagaat tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta
    15601 aaagagcaaa aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac
    15661 agctttattg tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt
    15721 cgggagatga tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa
    15781 gcaacagcaa tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa
    15841 gcacaagcac gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc
    15901 catggccgtc cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga
    15961 atccaagacc cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc
    16021 caatcaccaa gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct
    16081 gctgatatcg atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg
    16141 gctgaagaaa aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt
    16201 gccagtgaca cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct
    16261 gaggctgaat tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt
    16321 gttttaaaaa caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat
    16381 cctttgacag acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca
    16441 ggggcatacg gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat
    16501 tacagtatcg taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa
    16561 acaaaaaagc ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt
    16621 gaaaagatta cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc
    16681 cgggcgaaca agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa
    16741 agcaacaata atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc
    16801 aatcagggtc tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc
    16861 ctttagttca acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag
    16921 aataccaatg gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata
    16981 gactttgccg tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac
    17041 tgggtcattt acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc
    17101 ttttgttgca actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt
    17161 tgcgccattt gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat
    17221 cttattcaaa attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc
    17281 aatgatcatt gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg
    17341 caaaccgcct actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc
    17401 taatccagag ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa
    17461 catagcaggt tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc
    17521 ttctttttta ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat
    17581 atttgataaa gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat
    17641 atcgatggca ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc
    17701 gaatacggca ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga
    17761 gatccagctt ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt
    17821 tggtaacaat gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg
    17881 gaagaagatt tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc
    17941 ttgataacca atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc
    18001 ggctgtggaa gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa
    18061 aacgattcct aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac
    18121 tggaagaaaa tggaaaattg cttcaccggg taaccacaaa aaggcattga caccattcca
    18181 aaacttcgag tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac
    18241 atttctgaat ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat
    18301 ttctgctaaa acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt
    18361 tccttgttct ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt
    18421 agaaacatcg tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac
    18481 gctaggtata tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg
    18541 catacgagtc gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa
    18601 cagcttctcg gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg
    18661 tctatgcaag ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt
    18721 attaaaaagt acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa
    18781 aaataggaac attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg
    18841 agtgagggaa aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt
    18901 ttagcgaaag aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt
    18961 tatggtgttt cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat
    19021 attcaaaaaa aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct
    19081 atttctggat tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg
    19141 atcatccata cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg
    19201 gagatcggtg cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt
    19261 atattagaca ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca
    19321 caaggatcga tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa
    19381 aaggagatca cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat
    19441 gacacttatg cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag
    19501 tattctgagt cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga
    19561 aaagtgtaaa tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga
    19621 taggatcaca aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact
    19681 gaaagaaaag ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc
    19741 atttagcggg aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg
    19801 tgaaccgtta ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag
    19861 caaaccaata acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg
    19921 aatagaagtt cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc
    19981 agtagatcaa ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata
    20041 tgaaaagatg gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata
    20101 cacaaagagc ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg
    20161 attgctattt gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcacagca tgacagcatt
    23641 gggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cactagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaagttt ttttgcgaaa actattttta tatcatatat atgtctaaaa tctatattat
    23881 aaaagaaatg ttgtttgatc agcttctctt cggtattagt tcaaaacaaa acggcaaagt
    23941 atatggagct actttgccgt tttgtttctc taatactcag gtcagtttat agacgctcaa
    24001 taaacggtgt tcaaaagcca gtttctcggt attaagtcaa atttatgcaa aaatgtgaga
    24061 agccattttc aaaaaatatt tcttaatact cgaaactgag cggctttttc acgacctctc
    24121 aataaacagt gttcaagaga cagcctatcg gcaataaggc tgaacgtctc tttcacaacc
    24181 tcttttatca atctgctact tcttctttct tagcgaaact ccaaatcagt ccgataacaa
    24241 aaccgataac tgctggtacg atccacccca tccccaattt gaaaaacggc aagtagcttt
    24301 ccgcaacata taaaagattt tgaacaatag gtgtttgttt gatagtttct gggcaagcgt
    24361 tcaacccatc aaaaatcgaa gcaatcaatg taaaataagt agtcattcga taaacagccg
    24421 tacgctgctt aaacaaagga ccaactaaca ctagtaaaat cagtgtcatt gctaatggat
    24481 agatgaacat caaaacaggc aacgaaaatt gaatgatatt cgtcaagcct acgtttgccg
    24541 ctaaacaagg aaggatacta gcaagtgcaa caaagaatgc gtaatttctt tgcggaaaca
    24601 aatctgtgaa tgtttctgca aaagctgtaa tcaaaccaat accggtcttc aagcaagcta
    24661 atataacgat aaatgctaat aagatactgc cataagtacc taaataatga tcagcaatct
    24721 gagccagcgt gatcccgcca ttttcactta gagcaaagct acctaagctc atagcaccta
    24781 aataagcgag caaagtataa atgattccca tcaatataat gctgatcgca ccagatttga
    24841 tcgtgtcttt agcgatttca gcaggttttg ttacacccat gttttggatt gttgtgacaa
    24901 tgatgatccc aaatgctaaa gcagcaagcg catctaatgt gttatatcct tgagtaaacc
    24961 ctgtgaaaaa agcatgctct tgataatttg gctgaatagg cgcttgattt acagaaccta
    25021 gtggattcaa aaaagcaagg agaagcaaag cacctaataa aaccaaaaat gcaggattca
    25081 ggaactttcc aacataatct aatatctttg tcggttttct tgaaaaccac caagccagca
    25141 caaaaaatac aatactgaaa attgctagat atagcgtctg tctgctagga tcgataaatg
    25201 gtgctaaacc aatctcgaaa gatgtggttg caaggcgagg taaagcaaaa aacggtccga
    25261 taactaagta aagcaagatg gtaaaaacca tcgcatatgt ttgatttatc cgttttgcta
    25321 attcatatac acctgagctt ttcgatacac caatggcaat cacccctaag aagggaagac
    25381 cgataccggt aaccaagaaa cctagattcg cccaaaaggt agcagcgcct gcttcttgac
    25441 ccaaatgaac gggaaagata agatttccag caccaaaaaa tagaccgaaa agcatggagc
    25501 ctataaaaag atagtcttta aatgataatt tttttgtcat acataactcc tttacggttt
    25561 ttttaaaagt aacaaaattt cgaaaaatat gcaacaattt tcagaaaatt tcctatataa
    25621 aacgacggtt atttaataac gtaagtgata aaataaaagc gctgaatcat ctgaggagga
    25681 atcatcgtga caaagtcgag attagaagca tttactgatg gagtggtagc cattgttttg
    25741 agagttcttg tattagagat caagatccct aatacatcta gctttcattc tttatgggtc
    25801 atccgaaata cattattagc ttataccatc agctttatat ttgttgcggt gatctgggtg
    25861 aaccatcatc gtatatttca gatggcagaa cgaattaatt accgagtggt ctggtcgaat
    25921 atctttttgc tcttttggct gactttatgt ccttctgtta ctagttgggt cgggcgtaac
    25981 cctgaagctt tttggcctga gatggcttat gtcttagtat acacgatgtg gagtttttct
    26041 tttggtatct tgatgaggca aatcatgaaa gcaaataaac cagattccca tgtcgtgaga
    26101 gttttgtcaa aggaccgtcg aagtcttatc tccatgatga ttaacttatg cttgattgcc
    26161 ggtgtctttt ttgtaccgtt gatcgggtta ttcggacgtt tttttgtatc tggtatttgg
    26221 attttttcct ataaaaaagc agatgcctat tatcagcggt tgtttccggg gaaatagaaa
    26281 agaggctggg acagaagctt ttaactccaa gaaataagcc gaaatttcac aaaaatttaa
    26341 gaagcaattt tcgtaaattc cttcttattt ctcgaagctg accacttctg tcacaactac
    26401 tttcttactt cttacgttca tatttcatat gatagattag taatagaagc aagaaccaca
    26461 caggtgttag taataaagcg attctcgtat cttttcctag gaacaagacg acacacacaa
    26521 aggccatgta aagaaatacc agataattac taaatgggta caacggcatt ttaaatgaat
    26581 gagctttttt gccgaggata cttttacgat atttcatgtg cgtgtagaca agcatactcc
    26641 agataaacaa gaaacaagta gtggcaatac tgcttactag tgtgaatact tcactaggca
    26701 tcacgtaatt caagataaca gaaatgaaaa tgacgatagt agaaaatgtc aaagcattcc
    26761 ctggcacatg atgtgttgtt aactttttga attttttagg ggcactgcct tcttgcgcta
    26821 aagaacgaag catacgtcct gtactatata ttgcactgtt gcaggcagaa gctgctgcac
    26881 ttaatacgac taaattgatc aaggaagcag caatcgtgat cccaatttcc gaaaatactt
    26941 ctacaaatgg actgttatct ggattcaagc tgttccatgg atagattgcc ataatgacaa
    27001 aaagagatcc taagtaaaat aagatgatcc tgataggaat attattgata gcttccggca
    27061 acactttttc aggattttct gtttctccag cgactaatcc aactaattct atcccagcaa
    27121 aagcaaaggt taccatttgg aaagctaaga taaatccttt tgcaccagtt ggaaagaatc
    27181 cgccatgaga ccatagattc gtgatactgg ctgtgccaat atctgtcgta tagtgggtga
    27241 ggatcatata agctcctacg aggataaagg caatgatcgc tacaactttg atcaatgcaa
    27301 accaaaactc taactcacca aacaatgaga cagccaccat attcaagcaa agaagaagac
    27361 ctaatgcaat cagttcagga agccactgag gaacaccagg cgcccagtag cgtacataca
    27421 ttccgatggc tgttaaatcg gccattgcaa tcgataccca gcagaaccaa tacgtccagc
    27481 cagtgatgaa agccgctttt ttgccaagat attctgcaac aaaatccaga aaagaatggt
    27541 tattggtgtt tgataacaga agttcgccta acgcacgcat aatgaaaaaa cagatgcatc
    27601 cagtaataag ataggcgagc aatatcgaag ggccagctag ctggatagac tttccggaac
    27661 ctaaaaacaa ccccgttcca atcgctccgc caatagaaat cagttggaca tgtctatttt
    27721 tcagtccacg ctgcagttct tgctcttcat tcatttttaa atcatcctaa ctaaaaaagt
    27781 ttaattactt ccatattaaa agagttttct gaaaaacaca actaagattc caaaattttc
    27841 agaaatttac cttttatgag taattcataa aaaagaactg cggtaaacac cgcagctctt
    27901 tgtcccaatc agctattgat cctaagcatt taaaatacgt gaaaggaatt cttttgtacg
    27961 ttcttctttc ggatggacaa agatatcttc tggtgtacct tcttctgcaa tcacaccttt
    28021 atccataaaa atgacacggt cagatacatc ttttgcaaat tccatctcat gcgtcacgat
    28081 aagcattgtc aagccagtat gtgctaagtc tttgatcgta ttaagcactt cgccaaccat
    28141 ttcagggtct aacgccgaag taggttcgtc gaatagcaat acatctggat tcattgataa
    28201 tgcccgagca attgcgacac gctgtttctg tccaccagat aattgtgctg gtttggcttc
    28261 gatataacga tccataccaa ctttttccag attttcgatt gctacttttt tggcagtttc
    28321 tttatctcgt ttcaggacag ttgtttgacc agacatacag ttttccaaga cattcatatt
    28381 gttgaacagg ttgaaggatt ggaaaaccat acctagattc gttcgatatt taggtaaatt
    28441 atatttagga gctaatacat tttctccatt ataaatgatc tcgccgcctg ttggtttttc
    28501 cagtaaattg atacagcgca agaaagtaga tttaccagaa ccggaagaac cgatgatcgt
    28561 cacaacttca cctttattga ctgttacgct gatatctttc aatacttcat tttcaccgaa
    28621 gctttttctt agatgtttga tttcaataat tttttcattc atgattcttc ctccttattc
    28681 ctgcaaattt gaattgtcga tttcttcaag cttggtataa gctgaaggac catcgatttt
    28741 cttttctacc gcccgcagga ttctggtgat cgtaaaggtc atgactaagt agatgatccc
    28801 gacgatcgta aatgtttgga agaattggaa attcgcaccg gaagcagagt ttccttggaa
    28861 gaacaaatca gctacgccga ttacacttaa aactgctgta tctttgatat tgataacaaa
    28921 ctcatttcct gttgctggca agatattccg taaaacttgt ggaataacaa cttttctcat
    28981 cgtttggcca tgggtcatac caatggcttg cgcagcttcg aactgccctt catctactgc
    29041 aaaaatcccc ccacgaacga tctctgtcat gtaagctcca gtattgagag agacaataaa
    29101 caaagcggca atcgttcggt tcaatgaaat gccaaaagcg agtgccagac cgtagaagat
    29161 gaccattgct tgtaccatca tcggtgttcc gcggaatact tcgacataga tagaaagaag
    29221 tgcatttccg attttttgga agaagcgagt cagtgcattt cctgattcag gtaccgaacg
    29281 gaagacacca atcagtaatc caagtgtagt accgacaact gtcccgatca atgcgatgaa
    29341 caaggtaagt ccagcacctc gtaagaacat attgccgtat tgtttccaaa tcgtagtgaa
    29401 atcagaaatg atgccaggtt tttcttcact atcagttgca gcaggctgat ctttgactgc
    29461 ttggtccata attttggttc gttcatcgtt agagatgcca gaaagaatct ggtttacttt
    29521 ttggatatcc gggtcgcctt tacgcatacc aacagaaatc tgaacatctt ccgggtttgt
    29581 ctggaagcca tctgcaccgc tgaattcaag catttccaag tctttgttca cactagttgc
    29641 cgttacacct tccggacgtt cgctgacata accatcgatc attccagaag ctaaagctgt
    29701 tctcattgct gagaaattat ccattgcttg ttgtttctgc acatctggta tctgatcgat
    29761 cacagtatag tggaatgtat ttaactgagc agtaatcttt gctccagaaa gatctgctaa
    29821 actttttgct tttgcatatt tgctatcttt ttgaactact actactaatt gtgattcgta
    29881 ataaggatcg gtaaaatcaa tttcttttcg tcgttcagca gtagggctca ttccggcgat
    29941 gatcgcgtcg atcttgcctg attgaagggc aggagccaga ccatcccatt tcgtttggac
    30001 gatgactaat tttttcccta aaccatctgc tactttttta gcgatttgaa catcataacc
    30061 gccggcgtaa ctattttggc cttgaattgg caaggcatta ttctcatctg tttgttgaga
    30121 ccagttgaag ggtgcatacc cagcctccat acctacgcga aactcatcgc tcggtgtttt
    30181 ttcatctgca tttgccagag atcccacact gaatagtgag aagacaaaag caaatagtac
    30241 ggcaactgaa accatatttt ttttcatttt tttctccctt tctgattata tgatacacga
    30301 gcggtctaga tgaaatgcgg taaagcttta tctgaaaaaa taaaaagcga ccgatttata
    30361 gatataaaaa ggccgctaaa attccataag gtgataaacc tctcacaaaa catagcgcaa
    30421 cttagcatca ctgctaagac agtccgcaag ctcttaactt gcgtcccaac atacactcca
    30481 agcaaaaaag tgcacatttc ggcgatcctc cctattcctg cttctccatg tttgcttcac
    30541 tccacagggt taatgattct cgcgacctct acctcattga ttgaggcatc tcgtattcag
    30601 ttatttatac aaaaaaagtt tacgatactc gagaggcttt gtcaatctat aactgctgtt
    30661 ttttgaaaaa atactgataa atatagaaat ctttactttt accgaaaaaa caatcaaaat
    30721 gtgaatcatc tatccattgc aaacgatagt ataattatac acaaaaatgt atgtaataca
    30781 ataaaaaaag aactagaaca gaaaatttcc tgtgtccagt tccatctcga tcatttaagc
    30841 tgccgctttc tttggctcac gtcctaggat cgcttgcaaa agaacaacga cgccataaat
    30901 ggctaatatt agataaatca aacttgagta ttgggtgatt ccccagcccc atgttcgata
    30961 tacggctaat gtaatggcta aaacaattgc ggcaatcacg ttgaataaag caaaagccca
    31021 aagatttcca ttttctttgc gtacaagata aaaaacagag aaataaacgc ttaacgctaa
    31081 ccaggcgata caagccagaa taacgcccca ataaataaag aatggtaaca tatcgattca
    31141 cctcactttt atacagcagt attgtaacac gttttcattc ttttgtcagt gaacattgtg
    31201 ataaattgtt caaatgccca taacactttt ttattcccat ttttctgact tttcaacaat
    31261 aaatttgttc gagtatgggc tataatggaa agtgaggtga caaaacatga aacaattaac
    31321 agtagacgaa gcagcaaaag agatattagc ttatcagcaa attacatttt tgaccggtgc
    31381 aggggtatcc acaccttctg gagtgccaga ctatcgatct ttgtcaggaa tctaccacgg
    31441 gatggagcag ccggaatact tgctgagtca tcaagcaatg gtgaatgaac cggataaatt
    31501 ctatcaattt gtcaaaaaga tttatcatcc tgaagcaaaa cccaatatca ttcatttgga
    31561 aatggcacat ctagcgaaag aaaaaaatgt ttgggttgtt tcccaaaaca tcgacggttt
    31621 gcacgcaaag gctaaaagcc cgcaactcgt caattttcat ggaagtttgt atcaatgtca
    31681 ttgtcgaaaa tgtcaacaaa cggtagactg gaaagaatat cttcacagcg acaaacatca
    31741 agcatgcgga ggacaaatac gcccagacat cgtgttatat ggtgaagggt ttcaagatgg
    31801 agtcatggag caggcggctt atgccgtcag ccaagcagag ctgatcgtca ttgttggaac
    31861 gagttttcaa gttcatccgt tttgtgatct ggtacagttt cgccagccgt cagccaaaat
    31921 cttagtaatc aatcaaacgc ctgtttattt agcggagcct tatacgttta ttcaagaaga
    31981 cggagcggtt gttttcaaaa aaatacaaga attaggagca gattatgact gaattcaaaa
    32041 ccgaaaaaga aaaaatgatt gcaggcgagc tttattttgc caatgatcct gagctggttg
    32101 ccgaccgtat gtttgcaaga agtcaaagcc aaatcatcaa ccaagcagaa tcagcggaac
    32161 tgcgatccca attgttgaaa gagacttttg gccgtacagg gaaaaaaatc tatatggagc
    32221 cagttatcaa ttttgattac ggatataata tatttgttgg ggagaatttt tatgcaaatt
    32281 tcaattgtac atttttagat gtcagcacga ttgaaatcgg tgataactgc atgttcgctc
    32341 cgaatgtcca gctttacacg gcgacgcatc cactacatcc agtgaaacgt aacagcggtc
    32401 tggagtacgc aaaacccatt aaaatcggta ataatgtttg gttaggcgga ggagttatcg
    32461 tcacgccggg tgtcactcta ggggacaacg tagtagtcgg cgcaggttcg gttgtgacca
    32521 aatcttttcc cgacaatgta gtgattgcag gaaatcctgc tcgtatcatc aagacagtag
    32581 aggaagaact aacagaagag tctcttgaaa cattacgtca taagatcgat atgatcgatc
    32641 gagagttgat tgctttatta gaaaaaagaa tggatacggt aactaaaata ggacaagtga
    32701 aaaaagaaga aaaccaagca gtttatgatg caaaaagaga gcagcaagta ttggataaag
    32761 ttgttagtct gctgaaaaat aagggatata aggaaacaat aacagatacg tatgttgatt
    32821 tgatgaaaca ctcgcgcgaa taccaaaaca aaatgaagga ggaataagtg tgatcgaagg
    32881 agagacacgg cgaaaacaaa tcatgcaaac cttggcaaat acagaaaaac cagtgagtgc
    32941 tagcaagttt gcgaaaactt ttggagtcag ccgtcagatc attgtaggcg atattgcttt
    33001 actacgagct gcaggtaaaa gtatcgtggc aacagcaaga ggttatatcc tcgaaacaga
    33061 agaaaccaat actgggcaca tcagtaaaat cgctgtccag catggaaaag atcaaacaga
    33121 agaagaactg agactaatcg ttgaaaatgg tggtgaaatc attgatgtaa ttgtggaaca
    33181 tcccctttac ggtgagttag caggaacttt gcacatcaaa acgccacaag atatcgattc
    33241 ctttatgaga cgttatcaaa aaagtaatgc tactttgtta tccgaattaa caggcggcat
    33301 ccatctgcat acgatccgct acccagaaaa gcatatgctg aaaaacatca aacaaaaact
    33361 agctgaagca ggaatcctct acgaaggata acatcgtagc tgctactttt tatcctagaa
    33421 actattctat catctctgag ataaacaccc atatggaaga aataagaaaa aataagaaaa
    33481 gatgcgtatc caatacacag aattttttgg aattgcgatt tctagatgtc tatctaaatt
    33541 tcgattagtg gagaaacata aaaaagggaa gtgcagcttt tgagcactcc ccttttttat
    33601 aaagctttct tgtagcatag tatcgaagga acctgccaat tctctactcg atcaccaata
    33661 cgccttcttt tagtgcaaat ggattttgat cgttgatgtg gtcatagaac atcacaccgt
    33721 tgatatggtc gatttcatgt tgaacgacga tcgattcata attcttcaaa cgaatcttgt
    33781 gtttttcacc attcatatca taataagaca cagtgatttt ggcatggcga acaacatatc
    33841 ctggtacttc tcgatcaaca gataaacagc cttcaccttc ccctaaacaa gcatcttgaa
    33901 cagaatggct caaaatttta ggattataca taacagtact tagagaaggt ccatctgcct
    33961 ctgggtcagg acttggtacg tgaacagcaa tgattctttt agaaatatct aattgaggag
    34021 cagctaagcc aacaccgcct cgtaagtgta gttcttcagc tttgattgga tcttggctgt
    34081 tttttaagaa ctcaagcatc tcttttccta aagagatatc ttcttcgctt aatggaagag
    34141 aaacttcttt tgcaacttcg cgtaaggtcg gatttccttc acgaatgata tcatccattg
    34201 taatcatgga atatgtaccc ctttcttaaa agactgtgtt tcaagtctat tttcgcatta
    34261 tagtttacca caaaaatgga aaagtagtag taagattgtt tgaaaactac cttttcttaa
    34321 tgattaacta cttgattttc aacccggttt caggtaaagt atagctgtgt gctctaggca
    34381 catgacctgc cacttggtta agcgaatcac caacgtttta ctcagtcgca ggggaataat
    34441 cgaaagaggt gaaagaaatg gcaatttcaa aagaacgcaa gaatgaaatc atcaacgaat
    34501 acgctcgcca tgaaggggat actggttctc cagaagtaca aatcgctgta ttaactgaag
    34561 aaatcaacca cttgaatgaa catgcacgcg tgcacaaaaa agaccatcat tcataccgcg
    34621 gcctaatgaa aaaagttggt caccgccgta acttgttagc ttacttacgt aaaactgacg
    34681 ttcaacgtta ccgcgaattg atcaaacgtt taggcttgcg tcgttaattt tagtcaaaaa
    34741 gagtgggatt cacatgaatc tcactttttt tactcgtata tcaattaagt aaaattccgt
    34801 gatcaagcta gatggactcc tactaaccaa atgaaagctg ctcaaaagac ggctttcggc
    34861 agttttcatt tgtttagtag cgtcttgctt tcacgagaag gaaaaggaga agttatgtca
    34921 gaaaaacaag tattcaaaac gacatggggc ggccgtccct tacaaatcga agtcggtcag
    34981 ctagcaaaac aagcaaacgg agccgtttta gtccgttatg gagatacagt agtcttaagt
    35041 gcagctgtgg cctctaaaga agcaaaagat acagactttt tcccattaac gatcaattat
    35101 gaagaaaaaa tgtatgcagc agggaaaatc cctggaggtt tcatcaaacg agaaggccgt
    35161 ccaagtacgg aagcaacatt gactgcccgt ttgatcgacc gtccaattcg cccgatgttt
    35221 gcagaaggct tccgtaatga agtccaagta acgaacatcg tgatgagtgt agaaacagac
    35281 tgctcgccag ctatggcagc aatgctaggt tcttctttag cactatcaat ctcagatatc
    35341 ccatttgacg gcccaatcgc aggcgtagaa gttggtcgtg taaatggcga gtacgtcttg
    35401 aatccaacag tagaacaagc agaacaaaca gatatcgaat tgactgttgc cggaacgaaa
    35461 caagccatca atatggttga aagcggcgcg aaagaagttt cagaagaaga catgcttggt
    35521 gcattgctgt ttggttttga cgctatcaaa gagttagttg ctttccaaga agaaatcgtt
    35581 caagcagtag ggaaagaaaa aatggaagtg actttactgc aagttgatga agtattgaaa
    35641 aaagaaatct ttgatgcttc ttacgctaca atgaaagcag cagtaatgac tgaagaaaaa
    35701 cttgctcgcg aagataatat cgagcaggtg aagatcgata tccgcgaagc ttatgctgag
    35761 aaatttgcag gtcatgaaga tgaagatcac ttgttgaaag aagttaaaca aatcacagaa
    35821 gatcttgaaa aagatgtcgt acgtgaattg atcaccatcg ataagatccg tcctgacggg
    35881 cgtaaattgg atgaaatccg tccattgtca tcagaggtca gcttattgcc acgtgtacat
    35941 ggatcaggtt tgttcacacg aggacaaaca caagctttat cagcttgtac actcgcacct
    36001 ctaggagagc accaaatcat tgatggttta ggggtggaag tcagcaaacg attcatccac
    36061 cactacaatt tccctcaatt ttctgttggt tctacaggac gtgcaggctc tccagggcgt
    36121 cgggaaatcg gacatggcgc attaggtgaa cgtgcgttag cacaagtaat cccttcagaa
    36181 gaagaatttc cttatacgat ccgtttagta gcagaagtat tggaatcaaa tggttcttct
    36241 tcccaagcaa gtatctgtgc tggcacatta gcattgatgg atgcaggtgt accaatcaaa
    36301 gcgccagtcg ccggtattgc gatgggactt gtttctgatg gtgaaaacta tacgatccta
    36361 actgatatcc aagggctgga agatcatctt ggcgatatgg actttaaagt tgccggtaca
    36421 aaagatggta tcactgcttt acagatggat atcaagattc aaggaatcac agaacaaatc
    36481 ctaactgaag cattaactca agcaaaacaa gcacgtatgg aaatcttaga agaattgact
    36541 tcaacgattg ctgctccacg tgaagaatta agccaatatg caccaaaaat cgaaatgatc
    36601 cagatcgaac ctgctaaaat caaagatgtt atcggtaaag gcggcgatac gatcaacgga
    36661 atcatcgatg aaactggtgt gaaaatcgat atcgatcaag atggaaaagt aagtattgct
    36721 tcagctgatg cagaaatgat caaaaaagct atcaagatca tcgaagattt gaccaaagaa
    36781 gtcaaagttg gtgaagttta tctagggaaa gttgtccgta tcgaaaaatt cggtgcattc
    36841 gtcaacttga tcaaaggaaa agatggactt gtccatattt cccaattagc aaacgatcgt
    36901 gtcaataaag tcgaagatgt tgttaaacta ggtgatgaga tccttgtgaa agtaactgaa
    36961 atcgataaac aaggacgcgt aaatctgtca agaaaagcaa tgttgaacga agatggttca
    37021 acgaaaaatg aagaaaaata atttaattca taggaataat gtacttgtga tcgtgaaggt
    37081 gacaggggga caataattat tcgaaaaaag gggactgtga caaaagccgt gtcacagtcc
    37141 ttttttttcg aataaacggt gttcaaaagc ttgcatctgc ggtaataagt ccagccaagt
    37201 taaaaacatt aggagctgtt tttatttggc tgttcttatt acttgatgca gaacagcttt
    37261 tttacaacct ctccaataaa cgatgttcaa tcagctgtcc ctcgatatta gctcaaaaaa
    37321 cggcaaaata tgaggaacta tttttccgtt tgtttctcta atactcaggt caaaccgctg
    37381 atttcacaac ctctgattca cggtgttcca gaagcagctt ctacggaaat aagctgaaca
    37441 cttttgttac aacttctttt tttctggagt ttcttggcgc atatttttgg agtccttctg
    37501 aataaagcgt aaaataaaag tgagaaatat ggataaagga gggaaaggag atgctgaatt
    37561 ttttatggtc gttatttatc ggcggtatat taggtttgat agctggcgca attttaggaa
    37621 aggaagtccc gggaggcgta tctggaaata tcattatcgg ttttttaggt agttggctcg
    37681 gcgaattttt actaggacca ctgggaccgg aactcggcgg tttttatttg ataccagcat
    37741 tattgggtgc aattttttgc cttgctcttt attcatttgt ggcaagacgt atcagagaac
    37801 gtccaaagaa agaataattt tattcaaata agttgacact tcagtgtgtt acttggataa
    37861 ttagaagcaa tttaggaaag cgggtgtcat ggataagaat atcatctatc attcaagctt
    37921 acctaaagga tatccatata acaagaaatg agggaaaaac gtggcaacaa cgcacaatac
    37981 caaaaagata tcaatgactg gcctgcttgt agcgatggga gtcgtctacg gagacatcgg
    38041 gacaagtccg ctttacgtta tgaaatcgat tgttgaagat aatggcggat tgtcaggaat
    38101 caatcctgat tttgttatcg gatcagtctc attgattttt tggacattga ctctactgac
    38161 aacaatcaaa tatgtcgtga ttgcattgaa tgcagataac catggtgaag gtggaatttt
    38221 ctcactctac acacttgtcc gaaaaggtgg gaaatatttg atcattcctg caatgatcgg
    38281 aggagctgcc ttactagcag atggggtatt gacccctgct gtgacggtaa cgactgcgat
    38341 tgaaggcttg cgaggaattc cgcagttttt tgaccggttc ggtaataacc agaacgtgat
    38401 cgtcattatc actttagtta ttatttttgt tttattcatg gtccaacgct ttggtacaga
    38461 tattgtcgga aaagcattcg gaccaatcat gttcgcttgg tttacttttt taggcgtaat
    38521 gggattaatg aacttcagtc aagactggac agttatccgt gcactgaatc cttattatgc
    38581 tatccagctg ctttttagtg cagataacaa attaggcttg ttcattcttg gaaatatttt
    38641 cctggctacg acaggtgcag aggcgcttta ttccgatctt ggacatgtcg gcaaacgaaa
    38701 tattcgtctg agctggcctt acgtcaaaat ttgtttggtt atcaattatt ttgggcaggc
    38761 tgcgtggttg ttgaatgttt atcaaaaccc tgaagcacag caaatcaaga acctgaatcc
    38821 attcttccaa atgatgcctc aaagttggat cgtgatcggc gttgcttttg caacagtcgc
    38881 tgcagtcatt gcttcgcaag cattgattac aggttcgttt acgctagttt cagaagcaat
    38941 caagttgaaa ctgctgcctc ggttaaagat catgtatcct gggaacagta tcgggcaaat
    39001 gtatatccca gcagtcaatc tgattttatg gatcgcctgt tctctagtgg ttgtcacatt
    39061 ccgaacgtct catcatatgg aagctgctta cggtctatcg atcactgtga cgatgttgat
    39121 gacaacagca ctgctttact tttatcttat ccaaaatggg cattctcgtt ggcttgcata
    39181 tttagttacc tttttcttcg gtgcgataga agtcgttttc tttatctcaa gtgttgtcaa
    39241 attcttccga ggcggttttg tagccgttct gattggtttg atcatcttag tcgtgatgtt
    39301 tatttgggaa caagggaaca ttattcgcga atcgtcaacc gaggatgtgt ctttgagaga
    39361 ttatatcccg cagcttagag aattacgtga tgatacttct ttaccaatct atcagacaaa
    39421 tgtggtcttc ttggttcctg atatggctga agataaagtt ggccgacagt tcatctattc
    39481 gattttagat aaacggccta aaagagcacg agtctattgg tttgttcatg tggaagtgac
    39541 ggatgagcca tatacgaaag aatatcaagt agatatgatg gacactgatt ttattgtcca
    39601 agtgaatctg ttcttaggtt tcagggtcca acaggaaatc aacgtatatg ttcgccaagt
    39661 catccatgat ttgatgaaac aaggccgttt gccaaaacag ccacaaagat actctctgac
    39721 accagggcga gaagttggcg atttccaatt tgtcctgatt gatgaagtag tttccaatgt
    39781 gacaactcta ggaaaatggc aacgtcaaat catgcaggca aaactggcaa tcaaaaaaat
    39841 cgctacctcg ccagaaacat ggtttgggct agagtacagc gaagtaaaac atgaaactgt
    39901 tccgcttatc attggaaata ctcggaaaac atggttgaaa gagcggttgt gaaagtagcg
    39961 ctttgacctg aactaatgtc gaatgtcagc tacttgaaca ccgtttatca gaggtcatga
    40021 aaaagctgta ctgcaacaag cagtaagaac gagcagataa aaacagcttc tcatgttttt
    40081 catctgtttg ggcttaatgc cgtagatgca agcttttgaa taccgttttt atcagaggtc
    40141 atgaaaaagc tgtttagcaa caagtaacgc aatgattttg aagtgataag gagatgtggc
    40201 tgaaaaatgc cgcatctcct tttttattcc taaatatgaa tacgcattat tttcaatctt
    40261 tttgtagaaa aagggtacaa tagaaaaaga gaaaggcggg agaatatggt tatcaatttc
    40321 attattttat ttttgatgat tgcaattact tcattttttg tagcaagtga atttgcttta
    40381 gtgaaaatca gacgatcaag attggaacaa ctagaaaagg aaaatgtaaa gaacgccaag
    40441 ctagctcttc atgttacaca ccatttagat aactatttat cagctagtca attaggaatt
    40501 acgctaaccg gtttgatcat cgggtgggtc ggtgaaggat ctgtcgcggc tttactagaa
    40561 ccagtgatcg gtaaactacc ttttagttcg gctattagca gtacaatctc tgtggcgctg
    40621 ggatttattt tagttacgta tatcgatgtg gttattggcg aactgcttcc taagagctat
    40681 agtatcgtca atacggagaa ggtcgtcttg ttcgtagtta aaccacttca ttatttttat
    40741 aaagtaatgt ttccttttat ttgggtattg aatcattcag ctgcagggct agggaagcta
    40801 ttaggtgtgc gtctcgtatc tgaaggagaa gagacattgt ctcaagaaga gctgacatta
    40861 gtcgcattga attcttatga aaaaggagag ttgaccaaag aagaatatta ttatttggaa
    40921 aacgtgtttg aatttgatga taccttggca aaagatatac aagtagaccg tacgtccatg
    40981 caagtattcg aagcttcaga aaccgtcaaa gaagcgataa aagcttcgat tgaacaagga
    41041 catactcgct atccggttat cttagaatca aaagacaatg ttttaggtta tgtcaccttg
    41101 ccagatttga tcaagcaatc ttataaagat gaccagctga cagtagaaca gttgattgaa
    41161 gagccgatcg taacaactga aacgatccct ataaaaaaat tattgacgat catgcgaaaa
    41221 aagggtaagc atattgctat cttaaaagat gaatacggag ggacaagcgg cttagtgacg
    41281 attgaagata ttttagaaga aatcgtcggg gaaatccgag atgagacaga tttggacgaa
    41341 gcattgatag cggaacagtc agatggctct tatatcatct ccggcaaact aacattagat
    41401 gatttccagc gttattttca tgtagagatt ccagagtttg aagaaacgaa ttttactaca
    41461 cttgcgggct ttgcttctag ccgatataaa gaaataaaag caggaacaat cattgagatt
    41521 gcatcattcc gtttcacggt attagaatac cagcatgcac atatcgatta tttcaaagta
    41581 gagtccacgg aaagaaaaac agaataaaag aaaaaaggct gtgacatttt ttgtcacagc
    41641 ctttttgtta tctaaaaaac ctgttttcgg taaacgaaga agatattttc aataaaagtt
    41701 ttcattttta gccgcaacga tttcttttaa tcaaggctat cttgcttctg catgttctaa
    41761 tgtgaaatgt tcctcttcac ccatgtgttt caattgtttc atcgaacgca tataagagta
    41821 aagcaacacg gcaacagaac cgatccaagc taaaggagaa gctgctgctg ctcctgggta
    41881 tccccacatt cctgtaagaa cgatagctgc aaaagaacgc ataagcaatt ccatcatacc
    41941 ggcgatcgta gggatcttgc tttgtccaag cccttgaagt gtgtagcgta aaatgaacag
    42001 gactgctaag atccagtaaa gagacccatt gatattgaag taggtttgtg ctaattcaaa
    42061 tacacgtgtt tctgatgggt taacaaacaa ttgaacaaag aaatgaccga agaaaatgac
    42121 gatagcacct gctaagagac taaatccgac actcatcagt aaagtttgac gtaccccttg
    42181 caagattcgg ccatattctt tcgcaccata gttttgtgca gtgaaagttg ccattgcaat
    42241 accaaatgac atcatcggct gatttgcaaa ttggtcgata cgaccagcag cggcttgagc
    42301 agctacgaca tctgtcccta gactatttag tgctgcttgt aacacgatag caccaacagc
    42361 gatgatcgaa gattgaaacg ccattggcaa agcagcattt aggtgtacag caaactcttc
    42421 tttttcaaat ttgaaatctt ttttgcgtaa ctgtaacaaa ggcatttttt tcttgatata
    42481 cactagacac agtacgctgg aagaaacttg tgcgattact gtagcaatag ctgcaccttc
    42541 cacacccatg ccaaaataga taataaagat caaatcaagt acgacgttga tgatgaccgc
    42601 aatgatcaga aagaatagtg gtgtgcggct gtcaccaagt gcgcgaatga cattagaaag
    42661 caaattgaaa ctgactgatg caaagatccc taataaaata attgaaataa atgtttgtgc
    42721 ttgatcaagt atttcaggag gagtttgcat caattgaagc atcggacgaa taaacaggag
    42781 acttaggaca gttaaaatca cagtgacgac aagactaatg acaacactag cagcaaaact
    42841 tttcttcaga ccccgataat cttttgcacc gtaacgttgt gcggtaataa tggctaaacc
    42901 agctgttaaa ccttgggcaa agccaatgat caaaaatgtc aggcttccag ttgcaccaac
    42961 cgctgccagc gcatttttac ctagcgtctg acccacgatg atcatatcga tcatattgta
    43021 gaactgctga aaaacatttc cgatcagtaa aggaacagtg aacatcaaaa tcagtttagc
    43081 ggggcttcct tttgttaaat cgcgcatctt ttaaactcct tatatcttta aaatttagtt
    43141 agtagtatat agcgtttatc ctgagaatac caattagaaa tcaatgataa tttatgaaac
    43201 tccataaaaa gaagccaaga attgagtcaa agaatcaaca acttggcctg gtctgtaaaa
    43261 taagggacat ccacgtttat ctatcacctt aatattgtct aatctcactt ggtaaaagga
    43321 tcgtttctct cgtaccgtca tcataggcgt atacttgagc aggaaattgg ttcgaatagg
    43381 caaacggcaa atcaatatcc atttccacat tgcttcctgc ttgagaaaaa tgcatcgtca
    43441 cttttccacg attttcgatc aaatcaaagg ttaatatatt ttctaatgga atgactccct
    43501 taagatctag gtcaataata aaccatatac tgtcaatcaa ttcatctggc aaacttgata
    43561 cgacaccaac tgaagcgtaa cggttgcggc tgctatcaaa actttcaaac atctgtttaa
    43621 cctccttcga atcaacgaat gttttatttt tataattaat cctaggataa actagaaata
    43681 cttacttcaa cgagggttca ttctaataaa gaatcaggaa aaatgcaaca ataattgaat
    43741 actttttttc aaagtataaa tttttataaa ggtacgataa aagtatgcga ggaaaagctt
    43801 ggtaaattag gatttttcgt ttgtaaagcc atttacaaaa gtggaagccc catatgaaaa
    43861 taaacgatta gaaataaaaa aggcgtgtta aaagctgctg acccgccgct tctaacacca
    43921 cctgattgtt tcagtattat tcttctgttg aaccgatcac ttctggttcg ccaccttcac
    43981 ctgtgctttc ttcttcttca ctttgagcga ctacagcagc gatttgctct tcactgtcgg
    44041 tcacgaattt gtaatcgtcg ttttttggaa gatcggctac tgtaatagaa tcacctaatt
    44101 ccaagtttgt cacgtcaact tcaattcgtt caggcaattt gtctggtgta gcagatacga
    44161 ctactgtata caagttttga gctaacactc caccagattt agcacccact gattcgccaa
    44221 caagaacgac ttctgtttcg acttctgttt cttccgacat gtttacagat agaaattctg
    44281 catgttcgaa atgattggta aaagtgttcg tttggatctt gtgaaccaat gtattgactt
    44341 tttgtccatc gatgtccatc gtgatgactg tgttcgctcc atgttcacgc aacaatttgc
    44401 ttagtgtcaa accatcgaat gagatagggg tactttctac tttataccca taaacaacag
    44461 ctggaacttt cccttcgtga cgaagtttgt ttcttaatga acggggacgt acttctcttt
    44521 tacttacttc taatgatact gacataacca aaattcctcc ttaaaatgtg actgtctgct
    44581 ttggtaacgg acagatttta tttaagtgaa ttctaaaggc taatctcgtg cacatcatcg
    44641 aaggcagggc gcttaaaaaa gcgcaaaagg agagatgcgc gcatctcccc ttagaaagtc
    44701 aggattcaac ttttctccac caggtcatta cgctgtgtat gagaaatcca attcacttta
    44761 ctatttaacc gtaacgtgaa ctgttaatta agtcaaggaa taactatgat gatgtatttg
    44821 caagcaagaa tattcaaggt ataattaatt agtagtaata agaaaggaaa cagcatgcgt
    44881 ttagataaat taatagaaga aaaattagaa acgacacgca aggaaatgaa gcggctgttt
    44941 gctttgaagc aagtgatgat agatggcaca gtcgaatttc gacaaaatcg aaatgtagat
    45001 agtttactgc atcaaatcga agtagcaggt gaacacttag aaacaaatga gtcctattat
    45061 cttctcaata aacctgaaaa agctgttaca gctgtatcag atccagaaaa gacgacagta
    45121 atcgatctga ttgcaagtgc cgatcgtttc caaccattat atccagtggg aagactagat
    45181 agagatacaa caggactatt gctgatcact tcgaatggac aattgggata tgaaatgcta
    45241 cttccagaaa aaaaggtttc aaagacttat caagtagttg tgaacgaaag ggtgacaccg
    45301 gcagacgtaa cagcatttga aaatggaatc gtattcgctg atgggtatca atgtaagccg
    45361 gctgatttaa aaatactcaa agcagacaag caccaaagta cggttttatt gacgatccaa
    45421 gaaggaaaat tccatcaagt caaaaagatg ttcttagccc aaggaaagaa agtgaccgca
    45481 ttgaaacggc taagcatggg accattggaa ttagatgaac agctaggagt aggcgagtat
    45541 cgatcgttga cattagcaga gatgaaaaag ttaagtattt attttaaata ggaggtcaaa
    45601 aagatgaaat ataaaacttt attgtttgat gtagatgata cattgttaga ttttcaatta
    45661 actgaagcca atgctttaag tgctttgttt gcagaacaag gaatcacatt gacaccagaa
    45721 atcgaaacca gctataaggc tttgaatcat catttatggc aggagtttga aaaaggcaga
    45781 ctatcacgag aagaaataat aggcagtcgt tttgggttac ttttccagca atttgggaaa
    45841 acagtagata gtgatcaaat ggaaaaacgc taccgccact acttgaacca aggtcatgat
    45901 cttgttccag gaagtctaga aatcctgaaa aaggtccatc cgcatgctga tctttatatt
    45961 gtgacgaacg gtgtgtcgca cacgcaacat cggcgattaa cagatgcagg aatgcttgat
    46021 tacttcaagg atatctttgt ctcagaagct gtcggagcgc aaaagccgat gaaagaattt
    46081 tttgatcatg tcttttccca cattcctaat tttgataaaa agcaaactgt gatcattggt
    46141 gattctttga cttctgatat caaaggagga aatatggcag ggatcgatac gatttggttc
    46201 aatagaaata aattaccaga aatcgaagaa atccagccta cttatcgaat cgattcatta
    46261 gaggaacttt attcattatt ggaaattgaa aaggattaat tttcagaaaa atatagcatt
    46321 ttcgtgtttt ttcgctataa tagattagaa tgaaaaaacg gatacgaaag aggttttagt
    46381 caatgacaaa aagcaagcca attatcattg gtgtgacggg tggatccgga agcggaaaga
    46441 caagtgtcag ccgtgcgatt ttcaacaact tcccggacca ttccatcatg atgcttgaac
    46501 aagattctta ttacaaggat cagagccatt tgagttttga agaacgattg aacacaaatt
    46561 acgatcaccc atttgccttt gataatgatc tgctgattca gcatgtaggc gacttactga
    46621 actataaagc cattgaaaaa cccgtgtatg actatgtagc gcatacaaga agtcaggcaa
    46681 cgatcattca ggaaccaaaa gaagtgatca ttctagaagg aatcctgatt ttagaagacg
    46741 aacgtctgcg tgacttgatg gatatcaaag tatacgtaga tacagatgat gacattcgta
    46801 tcattcgtcg tatcaaacgg gatatggaag aacggggacg cacattggac tccgtgatcg
    46861 aacaatattt gacagttgtt aaaccgatgt atcatcaatt tatcgaacca acgaagcgct
    46921 atgcggatat cattgttcca gaaggcggag aaaaccacgt tgctattgat ttgattacaa
    46981 caaaagtagc tagtttctta aaccataaat agtgcgcagc gaaacagttg aacggactgc
    47041 gaccgtttga aaagcaagga ttctgctttt tgaacagtca ccagccaact gtttttttat
    47101 ttataacaag aggttgtgaa aacagcatct tgacctaagt attaaaaaga agaaacggaa
    47161 aatagctgtt tatattttac cgttttttga gctaataccg aaggtcagct gattgagcac
    47221 cgtgaagtag aggttgtaaa aaagctgtct ttgcatcaag cgataagagc atccaaataa
    47281 aacagctcct cacgtttttc gttgggttgg gcttattatc gtagatgcaa gcttttgaac
    47341 accgtttaac gagaggttgt aacagaagtg gtcagatgca ataaataaga agaaacttac
    47401 gaaaattatt tctcgaattt gtgtgagatt tcgacttatt tttttgaaga agctcttttg
    47461 tcgcaccccc
//
LOCUS       DAXLPQ010000017        46219 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.017, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000017 DAXLPQ010000000
VERSION     DAXLPQ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.017"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            160..840
                     /locus_tag="ACF3UO_001173"
     CDS             160..840
                     /locus_tag="ACF3UO_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFD3657214.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="ACF3UO_001174"
     CDS             930..1964
                     /locus_tag="ACF3UO_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFD3657215.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="ACF3UO_001175"
     CDS             1978..2313
                     /locus_tag="ACF3UO_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657216.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="ACF3UO_001176"
     CDS             2297..4777
                     /locus_tag="ACF3UO_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657217.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="ACF3UO_001177"
     CDS             4833..6392
                     /locus_tag="ACF3UO_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657218.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="ACF3UO_001178"
     CDS             6389..7753
                     /locus_tag="ACF3UO_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFD3657219.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="ACF3UO_001179"
     CDS             7924..8994
                     /locus_tag="ACF3UO_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657220.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="ACF3UO_001180"
     CDS             9009..9677
                     /locus_tag="ACF3UO_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657221.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="ACF3UO_001181"
     CDS             9697..10275
                     /locus_tag="ACF3UO_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3657222.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="ACF3UO_001182"
     CDS             10676..11587
                     /locus_tag="ACF3UO_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFD3657223.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACF3UO_001183"
     CDS             complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACF3UO_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFD3657224.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="ACF3UO_001184"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="ACF3UO_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFD3657225.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="ACF3UO_001185"
     CDS             13579..14127
                     /locus_tag="ACF3UO_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFD3657226.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="ACF3UO_001186"
     CDS             14242..16602
                     /locus_tag="ACF3UO_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFD3657227.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="ACF3UO_001187"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="ACF3UO_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFD3657228.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="ACF3UO_001188"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="ACF3UO_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFD3657229.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="ACF3UO_001189"
     CDS             19108..20007
                     /locus_tag="ACF3UO_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657230.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="ACF3UO_001190"
     CDS             20000..21262
                     /locus_tag="ACF3UO_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657231.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="ACF3UO_001191"
     CDS             21423..23321
                     /locus_tag="ACF3UO_001191"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFD3657232.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="ACF3UO_001192"
     CDS             complement(23651..24370)
                     /locus_tag="ACF3UO_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFD3657233.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    24560..24607
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            24707..25039
                     /locus_tag="ACF3UO_001193"
     CDS             24707..25039
                     /locus_tag="ACF3UO_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657234.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="ACF3UO_001194"
     CDS             25026..27029
                     /locus_tag="ACF3UO_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFD3657235.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="ACF3UO_001195"
     CDS             27048..27518
                     /locus_tag="ACF3UO_001195"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFD3657236.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="ACF3UO_001196"
     CDS             27539..28123
                     /locus_tag="ACF3UO_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFD3657237.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="ACF3UO_001197"
     CDS             28138..29124
                     /locus_tag="ACF3UO_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFD3657238.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="ACF3UO_001198"
     CDS             29114..29425
                     /locus_tag="ACF3UO_001198"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFD3657239.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="ACF3UO_001199"
     CDS             29447..31228
                     /locus_tag="ACF3UO_001199"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFD3657240.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="ACF3UO_001200"
     CDS             31221..32597
                     /locus_tag="ACF3UO_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFD3657241.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="ACF3UO_001201"
     CDS             32604..33239
                     /locus_tag="ACF3UO_001201"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFD3657242.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="ACF3UO_001202"
     CDS             33269..34624
                     /locus_tag="ACF3UO_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFD3657243.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="ACF3UO_001203"
     CDS             complement(34816..36210)
                     /locus_tag="ACF3UO_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFD3657244.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="ACF3UO_001204"
     CDS             36302..37273
                     /locus_tag="ACF3UO_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFD3657245.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="ACF3UO_001205"
     CDS             37270..38052
                     /locus_tag="ACF3UO_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFD3657246.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="ACF3UO_001206"
     CDS             complement(38221..38592)
                     /locus_tag="ACF3UO_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3657247.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="ACF3UO_001207"
     CDS             38726..39169
                     /locus_tag="ACF3UO_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD3657248.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACF3UO_001208"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACF3UO_001208"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFD3657249.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="ACF3UO_001209"
     CDS             complement(40040..41407)
                     /locus_tag="ACF3UO_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3657250.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="ACF3UO_001210"
     CDS             complement(41391..42221)
                     /locus_tag="ACF3UO_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFD3657251.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="ACF3UO_001211"
     CDS             42384..42821
                     /locus_tag="ACF3UO_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFD3657252.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /gene="rpoE"
                     /locus_tag="ACF3UO_001212"
     CDS             42897..43517
                     /gene="rpoE"
                     /locus_tag="ACF3UO_001212"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFD3657253.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="ACF3UO_001213"
     CDS             43706..44212
                     /locus_tag="ACF3UO_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFD3657254.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="ACF3UO_001214"
     CDS             44229..45128
                     /locus_tag="ACF3UO_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFD3657255.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="ACF3UO_001215"
     CDS             45215..46099
                     /locus_tag="ACF3UO_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3657256.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
BASE COUNT        15236 a         7977 c         9766 g        13240 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaatttt
//
LOCUS       DAXLPQ010000018        46215 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.018, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000018 DAXLPQ010000000
VERSION     DAXLPQ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.018"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(445..975)
                     /locus_tag="ACF3UO_001216"
     CDS             complement(445..975)
                     /locus_tag="ACF3UO_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFD3657257.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            1080..1631
                     /locus_tag="ACF3UO_001217"
     CDS             1080..1631
                     /locus_tag="ACF3UO_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3657258.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(1784..2257)
                     /locus_tag="ACF3UO_001218"
     CDS             complement(1784..2257)
                     /locus_tag="ACF3UO_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3657259.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            2395..3867
                     /locus_tag="ACF3UO_001219"
     CDS             2395..3867
                     /locus_tag="ACF3UO_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFD3657260.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLTKAGDNA"
     gene            3864..4574
                     /locus_tag="ACF3UO_001220"
     CDS             3864..4574
                     /locus_tag="ACF3UO_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFD3657261.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            4926..5210
                     /locus_tag="ACF3UO_001221"
     CDS             4926..5210
                     /locus_tag="ACF3UO_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFD3657262.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(5491..5910)
                     /locus_tag="ACF3UO_001222"
     CDS             complement(5491..5910)
                     /locus_tag="ACF3UO_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFD3657263.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGWFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(5912..6496)
                     /locus_tag="ACF3UO_001223"
     CDS             complement(5912..6496)
                     /locus_tag="ACF3UO_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFD3657264.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLNEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            complement(6543..8018)
                     /locus_tag="ACF3UO_001224"
     CDS             complement(6543..8018)
                     /locus_tag="ACF3UO_001224"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFD3657265.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDVIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVKDWEKYLK"
     gene            8199..8510
                     /locus_tag="ACF3UO_001225"
     CDS             8199..8510
                     /locus_tag="ACF3UO_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657266.1"
                     /translation="MKKMEESFPKAAKVENIANILKVTFENGEVKYVKSHWTEEITDD
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(8625..10961)
                     /locus_tag="ACF3UO_001226"
     CDS             complement(8625..10961)
                     /locus_tag="ACF3UO_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFD3657267.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSD
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            11103..11771
                     /locus_tag="ACF3UO_001227"
     CDS             11103..11771
                     /locus_tag="ACF3UO_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3657268.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     HIELIITDVMMPEMDGYDLVGSLRNARFDMPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSILTIGQTKLELDTYTVVQNQHSFILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            11774..12814
                     /locus_tag="ACF3UO_001228"
     CDS             11774..12814
                     /locus_tag="ACF3UO_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3657269.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRVIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQVNGKIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAIIRLSK"
     gene            complement(13054..13935)
                     /locus_tag="ACF3UO_001229"
     CDS             complement(13054..13935)
                     /locus_tag="ACF3UO_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3657270.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITDFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            14095..14823
                     /locus_tag="ACF3UO_001230"
     CDS             14095..14823
                     /locus_tag="ACF3UO_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFD3657271.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            14980..15297
                     /locus_tag="ACF3UO_001231"
     CDS             14980..15297
                     /locus_tag="ACF3UO_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3657272.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            15290..15898
                     /locus_tag="ACF3UO_001232"
     CDS             15290..15898
                     /locus_tag="ACF3UO_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFD3657273.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            15953..16744
                     /locus_tag="ACF3UO_001233"
     CDS             15953..16744
                     /locus_tag="ACF3UO_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFD3657274.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADYELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            16882..17370
                     /locus_tag="ACF3UO_001234"
     CDS             16882..17370
                     /locus_tag="ACF3UO_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFD3657275.1"
                     /translation="MKAEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            17421..18293
                     /locus_tag="ACF3UO_001235"
     CDS             17421..18293
                     /locus_tag="ACF3UO_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFD3657276.1"
                     /translation="MREKRAFYINGYAGIVGLIVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            18469..18831
                     /locus_tag="ACF3UO_001236"
     CDS             18469..18831
                     /locus_tag="ACF3UO_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3657277.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            18840..19592
                     /locus_tag="ACF3UO_001237"
     CDS             18840..19592
                     /locus_tag="ACF3UO_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657278.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            19606..21408
                     /locus_tag="ACF3UO_001238"
     CDS             19606..21408
                     /locus_tag="ACF3UO_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657279.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQTTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            21684..22724
                     /locus_tag="ACF3UO_001239"
     CDS             21684..22724
                     /locus_tag="ACF3UO_001239"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3657280.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSLDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(22776..24926)
                     /locus_tag="ACF3UO_001240"
     CDS             complement(22776..24926)
                     /locus_tag="ACF3UO_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3657281.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNN
                     NNGSNNSNNNNNNSNNGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPN
                     TANQSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFEHLGKPYVWGAKGPN
                     TFDCSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVG
                     IYIGNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPATSGSLTGSSILDGLDGS
                     FHFSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLF
                     GIKGSYNGSSVTFNTHEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDF
                     YKPTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEA
                     NAEILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQ
                     IPETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(25283..26656)
                     /locus_tag="ACF3UO_001241"
     CDS             complement(25283..26656)
                     /locus_tag="ACF3UO_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3657282.1"
                     /translation="METTMNPEQMVLYEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRDNMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(26656..27051)
                     /gene="rbsD"
                     /locus_tag="ACF3UO_001242"
     CDS             complement(26656..27051)
                     /gene="rbsD"
                     /locus_tag="ACF3UO_001242"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFD3657283.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(27079..27996)
                     /gene="rbsK"
                     /locus_tag="ACF3UO_001243"
     CDS             complement(27079..27996)
                     /gene="rbsK"
                     /locus_tag="ACF3UO_001243"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFD3657284.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(28105..29118)
                     /locus_tag="ACF3UO_001244"
     CDS             complement(28105..29118)
                     /locus_tag="ACF3UO_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFD3657285.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(29199..29798)
                     /locus_tag="ACF3UO_001245"
     CDS             complement(29199..29798)
                     /locus_tag="ACF3UO_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFD3657286.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILSNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTNN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHVVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            29983..30684
                     /locus_tag="ACF3UO_001246"
     CDS             29983..30684
                     /locus_tag="ACF3UO_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657287.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            30694..33405
                     /locus_tag="ACF3UO_001247"
     CDS             30694..33405
                     /locus_tag="ACF3UO_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFD3657288.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNAKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            33926..35554
                     /gene="treC"
                     /locus_tag="ACF3UO_001248"
     CDS             33926..35554
                     /gene="treC"
                     /locus_tag="ACF3UO_001248"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFD3657289.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(35614..36795)
                     /locus_tag="ACF3UO_001249"
     CDS             complement(35614..36795)
                     /locus_tag="ACF3UO_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3657290.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYQNSSFSEEDYF
                     K"
     gene            37047..38570
                     /locus_tag="ACF3UO_001250"
     CDS             37047..38570
                     /locus_tag="ACF3UO_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFD3657291.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVASI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFITQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYIEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(38639..39367)
                     /locus_tag="ACF3UO_001251"
     CDS             complement(38639..39367)
                     /locus_tag="ACF3UO_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFD3657292.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(39380..40660)
                     /locus_tag="ACF3UO_001252"
     CDS             complement(39380..40660)
                     /locus_tag="ACF3UO_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3657293.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKTLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(40801..41403)
                     /locus_tag="ACF3UO_001253"
     CDS             complement(40801..41403)
                     /locus_tag="ACF3UO_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFD3657294.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            41648..41854
                     /locus_tag="ACF3UO_001254"
     CDS             41648..41854
                     /locus_tag="ACF3UO_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657295.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            42166..42885
                     /locus_tag="ACF3UO_001255"
     CDS             42166..42885
                     /locus_tag="ACF3UO_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3657296.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(42966..43649)
                     /locus_tag="ACF3UO_001256"
     CDS             complement(42966..43649)
                     /locus_tag="ACF3UO_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFD3657297.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            43895..46081
                     /locus_tag="ACF3UO_001257"
     CDS             43895..46081
                     /locus_tag="ACF3UO_001257"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFD3657298.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        14964 a         8216 c         9223 g        13812 t
ORIGIN      
        1 ctgggagcat tatttcattt tgaagtcact aatttaactg tgtgaatatg cagttgttac
       61 aatctttgat aaacggtgtt caaaagcttg catctacggt aataagccca accaaacaaa
      121 aaatatgagg agctattttt atttggctgt tcttattact tgatgcagaa cagctttttc
      181 acaacctctg attcacggtg ttccaaaagt agcttcttcg gaaataagcc gaaattttac
      241 aaaaatttga gaagcaattt ccgtaaattc cttcttattt cttgaagctg accacttctg
      301 tcacaacctc tttcttaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
      361 ggcaaaacat gaggaactat ttttccgttt ctttctctaa tactcaggtc agaacgctga
      421 tttcacaacc tctctttcac aaccttattt tactcgttta taattttcat cgaaatattt
      481 tccgctacgg atatcatctg gcattccatc gtatggttct tcgctaataa catcttcatt
      541 gtctatacct gcatcaccca tataagtgat agtagcaaat tcaggaacaa gtaattttgg
      601 ataagtttca tatttttcac gagctgcttc catttctgcg atatgttcgt tttggaaagt
      661 aacagtgatt tctggatgtt cttcaaccca tttagggaaa aagatcattc cgtgaagttt
      721 cttttcattt ggcataaagt ccaatgccac gtctgtccct gttggctctg tccaagtgat
      781 tttgaatacg ccgtccgtca atttaacgat atcagcttct tggtctttta cccaacggcc
      841 tttgaccatt ccgccatgga tacggtaatc aacagtatgg tcatttttgg cataccattc
      901 atattcccaa ccattatcat acgtatagat aaagtgagtt ccaataaaat cttccaattc
      961 tttaaattct ttcatgttta agcatctcct tataaattaa aacatgtaat aaactacatg
     1021 ttttcgatta ctcatttatg atagaatgga tttaaagatt tgtcaaggag ggaaaactga
     1081 tggcaagaaa aaatacactt cgatatattt tgttagggtt attaagtaag aagaagatga
     1141 caggatatga attgaatcaa tcgttcaaaa atgaaatagg agaattttgg caagcaaaac
     1201 atagtcagat ttatcctgaa cttgcaaaaa tggaagagca aggaatcatt cagcatcaag
     1261 tagagatcac aggtgaaaaa ttggaaaaga aagtttatga attaacagaa gaagggaagg
     1321 aacaattggc agagtggatt catacaccca ccaatgaact accggttaat cgagacgaat
     1381 ttgttctgaa attgtatttc gtcaaagacg tgaatgatcc ggcattagta gaaattattc
     1441 agcagcagcg tgaccttcat gaagaaaaac gacttcatct attagagcga aaaaaaacga
     1501 tctttcctac tgaaaaagaa aaacatgaaa attacggaca ctacctgatt ttagcgcatg
     1561 cgatcaatcg ggaaacagaa tatgcaaatt ggctaacaga tgtattagaa gaaagtaacc
     1621 gaaaaaaata aaaaaatatc cgaacagtga tggagaattc ctttctatat gaaagaaacg
     1681 cagatcaccg ttcggatatt cttatgttca aacaggcctt ttttcaagta tttatgtagc
     1741 atctacttat taaaaagctt ggtacttagg agattagtgg cgtttagagt tcttttaaca
     1801 gctgttcgta gtcagctttt tcatcgacag gaaggagctt gtaagttaat tcgtctgtct
     1861 cgttgtcatg aatgatgtac atcttagcat tctcttcttt gaagttaccg atttgtaaaa
     1921 tcgtatagcg ttcgtcgatc aattcgatat ctttgattgc ttttgaaaaa actttacgga
     1981 catggtgcat tttcttttgg cggatttctg ccttttctgc agcttttgac aaagtaaatc
     2041 cgtcatctaa atattttttg atcagttcta cttttatgac tgtaggtaaa cgatattttc
     2101 taggacaatt cgcatcagct tcgatcgaac gaatgaatcc cttttgttcc caatacctta
     2161 attgacgtgg agacacacct acgatatcac ttaattcact gatgccaaca accaattgat
     2221 cattttccaa caaacgttta agggaagccc caaccatttt tgtcactcct tttgtcctct
     2281 tgcttccctt aattatatcc gtattaactt atgtgtcaag taggttgaca aatagcgaat
     2341 ttaggactaa agtattctag tagtttcaga aaaaattcag aaagaaggag aaatatgagt
     2401 aacaaccaac ccgtagatat ttacggaaaa ccatataatc ggacactttt agttgttgtc
     2461 ttattaattg gtacattttg taccgttttg aatcagacct tattgacgac agcttttcct
     2521 acattgatga aagctttcga tatttcagcg tctgatgtgc aatggttaac gactggtttc
     2581 ttgctagtca acgggattat gatcccaata acagcatggc tgatcaataa attcagttca
     2641 agaaatttat atctttctgc catgacgatc tttttgatcg gaacgattac ttgctttaca
     2701 gcacctaatt ttagtacatt actaatcggt cgcttgatcc aagcttgcgg tgtgggagta
     2761 tcgatgccat tattgcaaaa tatcatgcta tctattttcc cgccagaaaa aagaggatca
     2821 gcaatgggga tgtcagggat cgttattgga cttgctcctg ctttaggccc tacattatct
     2881 ggttatatca ttgataacta ccattggcgt gacttgtttg gtatggtact gccaatcgtt
     2941 gttcttgtct tggttttagc attcttccta atgaagagcg ttattccatt gtcaaatcct
     3001 agcattgata ttttatccgc tattttatca acgattggat tcggtagttt gctttacgga
     3061 ttttctagtg taggagatga cggctgggga agcttgaaag taattggttt cttagttgtt
     3121 ggtgtgattt tcatcgcatt gttttcatgg cgtcaattac atttggaaca tccattcttg
     3181 gaacttcgcg tattcaaatc atctacattc acgattgccg ctgttttagc tggtgtaaca
     3241 aatatggcga tggtaggggc agaaatggtc gtaccattgt atattcaaaa tattcgtgga
     3301 gaatcagcat tccattctgg cttgatgttg ttgccgggtg cattgatcat gggggctatg
     3361 atgcctgtta cgggtgcgat tttcgataaa tatggcgcga aacgtttagc catcacaggg
     3421 atgttcattt tgacagccgc aactgcacca tttgctttct tgacaaaaac gactccagtt
     3481 ttatatatcg tgatccttta tgcgatccgt atgtttggga tctccatggt catgatgccg
     3541 gtaacgactt ctggtatgaa tgcattgcca aataacttga tcagtcacgg gacagcggta
     3601 aataatacat tccgtcaaat cgcaagctcg attggtacag ctattttgat cagtgtgttg
     3661 acgaatgtga caaaagcaaa tatcccaagc aaatctgtat tggataatac accattagct
     3721 tataaagatc aggcaatcaa tgccacactg tcaggttacc atgccgcgtt tatcgtagcg
     3781 atcatctttg ggatccttgg ctttattatt gcctttttat tgaagaaaaa agaacctgtt
     3841 ctaacgaaag cgggggataa tgcatgatta ttggagtttt gattgtcagc ttgcttgctt
     3901 ttgctttaac gaacgtgttc gctaaaaaaa catggcaaac ctttttatct ttgattttcg
     3961 gactaatctt cgtcgcttca ctaagtttga tcgtcgctaa tttgtccaat cactttggaa
     4021 tggaaaaagt aacggaaaca aaaacagaaa aaattgtttc cagtgctgat tcccaaggag
     4081 cagatatgct tttgtataaa gctttaggga atggaaaaga aaaagtgtat ctttaccgaa
     4141 caaatgaaaa acaagaaaaa ccaaaagcaa ctggtacgga taacgaaaca aataaagtag
     4201 aaaagacaga cggcgatgct gaaaaagtga cgaaaactac ttattgggaa tacaaaaacg
     4261 acatgtataa attctggttc aatattgctg ataacaatca cgaatatgac agccgagtga
     4321 atacattcaa aatcccagag acatgggtag aattaagtac ggaccaagca gccaagttag
     4381 ctgaattagt taagaaacag caaagtacga tggaaagtga agcaaaagct tatgttcaag
     4441 acggtatggt aaaagcaatg actgaaaatc caaaaatgag caaagcagag caagaacaac
     4501 gtacgaaagc cttagctgct gaattccaac aacaagcatt cgcaaaatta gtgaaagaag
     4561 caaaaggcga ataatatttt gaacaccgtg taggaggttg tgaaaaagct gctctgcatc
     4621 aagcagtaag aacaatcaga taaaaatagc actccatatt tttcatctga ttggggttag
     4681 tgccgtagat gcaagctttt gaacaccgtt taaggaagag gttgtgagcc tgccgtttaa
     4741 ctctgagtca caaggagcaa tttcaaaaaa cagcttctca tgtttgttga atattgtgac
     4801 ttgtgaccga ggagttggca ggagaacacc gtttattcga aaaaaggaac tgcgacaaga
     4861 cttttgtcac agttccttct tttttttgct atgctatact agatgtaaaa aataggagaa
     4921 ataaaatgag ggaaatttat tcttttgaat caaaaatcta tgcttccgaa gtcggcaagg
     4981 gcggggcata tattattttt ccgtatgata taagaaaaga attcggtgct ggaagagtta
     5041 aagtccaagc aacttttgac aatgtgccgt acgaaggcag tatcgtgaat atgggtgtga
     5101 aaaatccaga tggttcagtc tgctacatcc ttggactacg aaaagatatt cgtaaaaaca
     5161 tcggtaaaga aatcggtgat attgtagcag ttacagtgaa gcaaaaataa aagaggttgt
     5221 gacaaaagac gtgtcacaac ctcttgataa acggtgttca aaagccagtt tctcggtagt
     5281 aagtcaaatt tatgcaaaaa tgtggaaacc catgtttaca aaatttttct tactactcga
     5341 aacgaagcgg ctttatcaca acctcttgat aaacggcgtt caatcagctg tccctcggta
     5401 ttagctcaaa aacggcaaaa tatgagaagc tatttttcca tttttttctc tcatactcag
     5461 gtcataacgc tgatttcaca acctcttctt tcataatggt ttttcaccat ctttataata
     5521 aactggttct ttgatatgga aatctatttt ttccaaccaa tctaaaatct tgtaacctaa
     5581 ctcttctgac atcggaaaag aggcgttgat ttgtgcattg gagatatggt caacatggat
     5641 accggaagta atcgtacaac ttcccggaac ggcagttttg atgatcacag ctattttttc
     5701 ggctaagaca tcgtctttat ggaaccaacc atcgtggcta gggaaacgta cagtttgcat
     5761 ctctgtatca cgagaaaatg tagtgactgt tccgatatgt ggtgtatctc cgcctgttaa
     5821 agtgatcaat aagtctttac cgattacttt aacagcagct tggatcgtga aacctagttt
     5881 ggttacttca actatcgttt ctttttccat attaatcacc ctgccaacgt tttgaatgct
     5941 catttacaat tccaaattga tccaaaagtt tcattgtatg gtgattaaca agatcttgga
     6001 tcgtttgagg ctgattataa aaagcaggaa ttggtggtat gatttgcaca cctagtcgtg
     6061 ctaatttagt caagttttcc aagtgaatgg catttaatgg cgtttcacga ggaacaatga
     6121 ctaactttcg ttgctccttc attgttacat cagcagcacg tgcaataaga ttgtcgccta
     6181 aaccaacaga gatacctgcg actgttttca tacttgctgg tacgatgatc attccatcgg
     6241 tcaaaaatga tccgctggcg acagcagcac ctaaatcttt gtttgaataa tggtaatcaa
     6301 acaggctttc gaattcattt agtgataagt cggattccag ctttaagttc tgttttgccc
     6361 atggactgat gattccgtgt gtttctatca tcggatattc ttttagtttc ttcactaggt
     6421 tgatggcata aatggtgcct gaagcgccac ttacaccaat cacgattttt ttcttccgtt
     6481 gtgccaattg ttccattttc cgcactcctt tttatgatgt caaaacagtt gcagatcatt
     6541 cattatttca aatatttttc ccaatctttt acttcttgga attttgcacg tacaaaatgt
     6601 tctttcatat cgaaaggaac tgtaccgtca aagatagttt ttgcactcat cccacggaaa
     6661 cgaatagagc caggattata ttctggtaat tctgatgggt ccaatggatg gtttctcatt
     6721 cctgggatca caatgacgtc tttatctcct tggaaacgag tgttgaaagt ccaaactaca
     6781 tcgttcatgt cgaaaatatc aacatcttca tcgactaaaa tgactgtctt caattctttg
     6841 aaggctgata aagcaagaat agctgcttga cgctgaatac cttcatccgc ttcgttttct
     6901 ttacggattt gcatgatggt catcaattta ccaccacctg caggaggatt gtagacattt
     6961 actacttttc ctggaatagc tttatcgacc aaggcaagaa tacttgcttc tgtaggaata
     7021 ccggccatag atacgtgttc ttcactggga ccaatcgttg tttgcatgat tggattgtct
     7081 tttcggtgag taactgcttt gactttcact acttgtacag ctggattagc atccccagta
     7141 tagccaggaa attctggcat tgcttttcct gagttcgtgt tgatatcttc ttgcattgtt
     7201 tcatttggca tgatttctgc ttcaatgatg aattcagcac gagcaatacc cacttcatcg
     7261 actgctatac catcaacgat ttgaataggt tcgttacgca aagctcctgc acaccatagt
     7321 tcattgtagc caagtggagt ggtaggtggt tcgaaagtcg tgccaatggc aattgctgga
     7381 tctaaaccaa tattgatagt gataggcatt ggtttattca aggcttcgaa ttgtttttgg
     7441 aagtgaccaa tgtggcgtcc gccaggcatg atgtacatac cgatcgtatc tttatcttct
     7501 agaaccatac gatggatcgt tacatcgctc attgtttttt ctggatctga tcctaagact
     7561 acacccattg tgatgtatgg accagcatct tcaggagtat ttgtaggtgc aggcaaaatg
     7621 ttgcgaatat cgaagtctgc atcggtagct agatgaacga cttcttgtgc tggagcgtct
     7681 gctttgtcta ctttcacagg tttgattgga ttttctacag cgtctttcaa gaaacgacca
     7741 agtgttcgat aatcatggtg caaaatttca cctacacgtt tacgactagc cattgttccg
     7801 atgttcacac gtgtgccggg gaaacctttg atattgttga aagtcatagc tggtccttct
     7861 tgagtcggac gttttactgt accgccagca ccgatataac ggtaaacacc agataattct
     7921 gcttcaggat cgatttcaat atctgtttcg tgatattgac ctggaagtgt ttttagttct
     7981 tcgatgactt ttcttaaatc atacggttga tctgtcatga gagattcctc cttagttgtc
     8041 tttacctatc tatagtaaaa ggtgaaaaag aggaaaacaa ttcaacttgt tcggtaaagt
     8101 attctacaat ggaatggatg cgtttttttg ataatagaat aaactatgat atacttatca
     8161 ataaaagaaa gcgcatactt agtgttggag gaaggaaagt gaaaaaaatg gaggagtcat
     8221 ttcctaaagc agcaaaagtg gaaaatatag cgaatatttt gaaagttaca tttgaaaacg
     8281 gagaagtaaa atacgtgaaa tctcattgga cagaagagat aaccgatgac ttgcaatttg
     8341 gaaaaaaagg aagaggaaaa agaaaaaatc ttctcgcact ttctcgtaat atgtggattg
     8401 ggactgaagt aacgattgaa gcagatggaa cagtattcat aaatggaaaa gacaggtata
     8461 cgccagaaga gttgtggtac aaaggaaaga aaagtatacc agaattataa aaaataatta
     8521 aaaaaaacag cgcgaaacaa ggaacatatt acttcctcgt ttcttgctgt tttctactat
     8581 ttcagcgctc ttatgactca aatctaaatg tggttgtcac aaccttattc tgcacgcaaa
     8641 gcgatagcgg cgtctttttt cgctgccatt cgtgcaggaa gatgaccgcc aagcatcgtc
     8701 aatatagtag agacgatcac tagaataatc gcatggacag gatttagttg agcaacattt
     8761 tttagatccg tcatgttgta taagatgcta ttgataggga atgtagctag ccatgcaata
     8821 aacacaccta atatcccaga agaaatacct aaaatacacg tttctgcgtc aaatacgcga
     8881 gtgatgtctt ttttacgtgc acctaaagct tttagtacac cgatttcttt tgtccgttca
     8941 atcacagatg tataagtaat gatactgatc atgatcatac ttgttactaa agagatccct
     9001 gcaaaagcaa taaggacata agtgatagca tccatcaatc cgccagtcag ttcagtcatc
     9061 gttccagcta aatcagtata aatgatttta tcttcatctg atttgccttt attgtaatca
     9121 tctagataat ccaagatctt ttctttgtct tcaaaattgt tcggataaat catgatactt
     9181 gaaggcaagc tgtctccacc taaataacta agcaatgttt gtttggcatt ttcgtcaact
     9241 ttttcagtag ttaagacatt tacatcactg tctctttgag ctttgacgat ttctgattct
     9301 ttgttttcgt tgacgatttg agtcgttaat tgatcgctat aagcgattcc tggagataag
     9361 agattcattg tagaagaaga tttcacgcgt aggatccccg agatcttcaa ttcatcagaa
     9421 gcattctgat acatcgcatc ataatctgta ttagggataa aattcccagt tggaagtttt
     9481 gtatagtaag tattgttgtt tactaatttg aatgttgtac caacgatatc atcaaaatca
     9541 agtttttcgt cttctttcac atcaaatcca agattcttca atgcgttgat attagtatta
     9601 ttattgccgt ctacgatcag cacgacatct gttgctgagg ctggataact tccggcaagt
     9661 aaagaataat tgtcttttaa aaagttttct ttgctagtgt caagctgtgt agggaaactt
     9721 gacactccca cacctgtcat tgctgacatc gtactagata aagaaagaga ttccgtatca
     9781 ggattttgat tcgagaagct gacaggctgt actttgccat ttacatcacg taaaagattg
     9841 attcctgtag tacgggtaaa tccgatatta ttacttaagt taggatcgat gtctgttacg
     9901 taatcgacgt atgtttgatc aatcttattc gtgtgctgtg ctttatcttc ttcgctgact
     9961 tttgcagtaa tcgttttgct gtctggataa tccgctttgc ttgcacccaa tccggcatcg
    10021 tcacgagtct ggttagtcgt taccttagaa atagtaatcg gaaatttcgc catcgtttca
    10081 gcttgcgtgt tatcgatttg tttttggaat ccagaagaaa gggacagaac gatcgcgatt
    10141 ccgatgatcc caatactgga agcaaaggag gtcaagaaag tacgtccttt ttttgttcgg
    10201 atattgttga aggaaagctt caacgctgtc caaaaactca tctttgttct gcgtaagtta
    10261 aattgatcat cttttggccg ttcgatgtga ggatgggaat ctgttaagat cttaccatca
    10321 gaaaattcaa tgatccgatc tgcgtattga tgggccagtt caggattatg tgtgaccatg
    10381 atcactaatt tttctttcga taactcttgg atcaattcca tgatctggat acttgtttct
    10441 gtatctaacg ctccggttgg ttcatcgcac aaaaggatat ctgggtcatt ggctagtgct
    10501 cgagcgatgg ccactcgctg catttgtcca ccagataact gatttggctt tttatgcata
    10561 tgatctgtca agccgacccg gtgcaatgca tcttctgccc gttttcgttt ttcgtcttta
    10621 gaaacaccac ttaatgtcat cccaagctca acgttttcaa taatgcctag atgaccaatc
    10681 aagttgtaac tttgaaaaat gaaaccgata gagttgtttc ggtaggcatc ccagtcactg
    10741 tccttaaagt ctttagtaga ctttccgttg attaccatat caccggaatc ataattatct
    10801 agtccaccaa tcacattcag catagtcgtt ttaccagaac cactaggacc taaaatcgct
    10861 acgaattctt tttgtctgaa agcgacagac acaccatcca atgctttggt ggtggtttcg
    10921 ccgactttat aatatttttt tatatctttt aattgaagca taatcaccct tctcccgtat
    10981 tgaaatattc ggtatactaa taagtatatc agaacaatga tcgtagtata cgaaataaat
    11041 gttaactgaa gatgaactac aagaaaaaat ctagaaattt ttcaaaaaac agagggagat
    11101 caatgaatcg tattttagta gtagaagatg atccgcaatt acagttgctt taccgttctg
    11161 tgttggaacg agcgggcttt tcagtcatca ccgcactgaa tggagaggat gcgctgaaaa
    11221 aactagaagc gacacatata gaattgatca ttacagatgt catgatgcct gaaatggatg
    11281 gctatgactt ggtaggatca ttacgtaacg ccagattcga catgccagtt ctgatgatta
    11341 cagcaaaggc tgatttcgag gacaagaaac gtggattcaa attaggtgca gatgattata
    11401 tgacaaaacc catcgatgtc aatgaaatga tcctgcgtgt ggaagcattg cttcgacgtt
    11461 caaaaatcaa ttacagcagt atcttgacga ttgggcaaac aaaattagag ctggatactt
    11521 atacagtggt acaaaatcag cattctttta ttctgcctca aaaagaattt ctgcttctgt
    11581 ataaattact gtcttatcca aacaagattt tcactcgcca gcagttgatg gacgatattt
    11641 ggggattaga cacgaataca gaagaacgaa cgatcgatgt acatatcaaa cgtttaagga
    11701 cccgttttga aaagacagaa gattttcaaa tcatcacagt acggggacta ggctataagg
    11761 cggttattta aagatgaaaa agaagctatt ttcacaatta tggatctatt ttgctagtat
    11821 cgtatttatt tcgatcttag taacactgct gtgttttctt ggttttattt tcttattgtc
    11881 tcgacattct atctcgcctg ctgaatcggc tggaaaacca acgttatacc cgttattcgt
    11941 ctttgcgggg ttcagtatgg tcgtgggtac aggaatatcg atttttgttg ggcggcgtat
    12001 cctgcatcca atcagtgcgc tagggacaaa tatgagtctg gtagcaacgg gagatttttc
    12061 gattcgaatg gatgaacagc agaaagtagc agaagtacag caactgtata aagatttcaa
    12121 cgttatggtc caagaactca atagtatcga gacactgagg aatgactttg tgtccagtgt
    12181 atcccatgaa ttcaaaacac cactagcaac aatccaagga tatgttcaat tgttacaagc
    12241 cccaaatctt tctgacgaag aacgccaaat atttttatat cgggtcatcg aaagtatcac
    12301 gcagctttca caattaacag agaacatttt aaaattaaac aaactggaaa accagcgtat
    12361 ccaactggaa aagaaagagt atcgattaga tgaacaaatc agagaagtaa tcgttttttt
    12421 gcagcctaaa tgggaaaaag aacagctaga attggatatc gaacttgctg cagtaaacta
    12481 tacaggtaat gaagagtttt tgtaccaagt gtggctgaat atcatggata acgccataaa
    12541 gtacaatcaa gtcaatggaa agattcatat caaattattt gagacagcca cagagatcgt
    12601 actggaagtg accgattcag gtgtaggaat gaatgaagag acccgagatc gaatgtttga
    12661 aaaattttat caaggagata caagccgtca gatttctggg aatggactag ggctttcact
    12721 ggtcaaaaaa attctagaac tacatgatgg acgtatcgat tatagcagta tcgaaggagt
    12781 agggacgaca gcaataatac gtttaagcaa ataataggaa aaaagaacaa aatacctaaa
    12841 aattctagtg aaggttttta gggattttta gacgtttttt tgtgattagc gaattgctct
    12901 taatgttctt ccggcataaa atcgctgatc ttctattgaa atacgagaaa cgttagatgt
    12961 gtcattgaat caatggcacg atgtaagaaa gagagcgaaa gtcatgcgtc gctctctttt
    13021 ttggggtgga tagatggaca gaaaatgtag ggcttagttt tcttcttgat ttaaatactc
    13081 ccaaaatgta tctgaagcca aagaatgctc accgacttta cgagtaaatg caagataact
    13141 ctctgttgtt ggagaaatag ggagaatcac agtattttct tttaatagat tcttgactgt
    13201 tttttccata acaatagcaa tccccatgtc atttgcaatc atattgatga tcaagtcgat
    13261 tcttgctcct ttataagaga tttttggttc aaatccagct tcgcgacaca gatctagtac
    13321 aggttgatac aagttcgtag tggggccaag tagcaaaaag ttctcctttt tcagttcgct
    13381 tagatccaat ttctttttac tagctaaagg atgattttta ggtagaactg ctacaaaatc
    13441 gtctgtttca gtaggcaacc actcaatcga actcggcggg gcctggaaac ttctagcaaa
    13501 gtggatcgtg tcactatgtt cattggcgtc attgtaagtt aattcgacac tttccacttc
    13561 tttcaactgg actgtaaatt caggatggcg tttcaaaaag tcggtgattt tggaaaaacc
    13621 tttataattg atcattgtcg gtatcgttaa gatatttaat gaaagattgt tgtctttcgt
    13681 ataggtttca agcacttctt gcatagcatg gtattgttct acgacatttt ttacatatgg
    13741 gagcaataag cttccagctt cggtcaattc gatttttcta tgggcgcgtt cgaataattt
    13801 gacgtctaat tctgtttcta acgaaagaat ctgtttagaa atatttcctt gggtggtgaa
    13861 ttgtcgatca gcagttttgg tgaaattcat tgtttcggct aaatcaagaa aaacttcgaa
    13921 tttatggata tccatcatat tcctcctact tattccaata aagaatactt taacacaaaa
    13981 aatgaattgg tgtaatcttc tctgtctgtt acaatctttc ttgcagcgaa agcaataatt
    14041 acagaaattt ttctgatttt tttcgcttcg tagaaaaaga gaggagtttt tttgatgcca
    14101 actggagttt tgatcaatgt aggttccgtt ttgcttggcg gactaattgg cggattagta
    14161 ggaaataaat taagtgaaca ttttaaagca cagctgacga tggtttttgg tgtgtgttcg
    14221 atggggatgg gaatctattc cattgcgccg atgaaaaata tgccggctgt tatttttgct
    14281 ttagtgatag gaacagcgat tggtctgatt gttcatttag gtaatgggat aaataagggg
    14341 gctgcgctga tgcaagtacc tatttctaaa atcttcccta gtgaaaagct tggtatgacc
    14401 cacgatgaat ttatcagtac attagtgacg gtcattgttc tattttgtgc aagtggtacg
    14461 gggatctatg gaagtttaga ttctggaatg acaggagaca gtacgatttt gatttctaaa
    14521 tctgtccttg attttttcac agcagctatt tttgcgtgta atttagggta tgtcgtttct
    14581 gtgatagcaa ttccccaatt cattattttt tatattttgt tcttattggc aaaatttatt
    14641 tatccattga ctacaccaga catgatctta gattttaaag cttgcggcgg attcttgatg
    14701 gtcgctaccg gttttagaat gatcaacgtg aaaatgttcc cagtagctga catgatacct
    14761 gcaatgatcg ttatcatgcc actgagctgg atgtggacaa attggattat gccactgtta
    14821 taataaaaat caaagagaag ccattttttt gctgactaaa aaggatcaaa tcttttagtc
    14881 agtttttttg tatttgacaa actgattttg aaactatatt atatgttgta taatatagat
    14941 tgaaataaaa tattacactt gagaatagaa ggtgacgtaa tgcacatcca gattccaact
    15001 gttcttcttg atggtactgt gttagcagca ttaagcaagg aagatatgta tgggtatgcc
    15061 ttaacaaaaa tcgtacaaga aagtctctct gtcagtgaat ctacactata tccggttttg
    15121 agaagattga aaaaagaagg atatcttgag acctatgatg aaccttttga aggcagaaac
    15181 cgtcgatatt actcgttgac accaatggga agtcgtcatt tagaagaaat tattgatgaa
    15241 tggattgttt ttcgagattc tttagaccgg ttattggagg agagcacaaa tgaatgaata
    15301 tttgaatgaa gttgtggatc atcttcaaga aattcctgaa gacgatcgtt ttgatttgat
    15361 ccagtattat gaggaatatt ttttagattc tggaaaaaca ttagatcaga tcattgatga
    15421 atatggtaca ccaaagcagt ttgccttaaa attaaaaatc agttactttt cagaagaaga
    15481 acaagcagaa aacgagttag tgaaaaatcc aaaaagacaa attcgcctga tttggttaat
    15541 cattatcggt ttatttgctt ctcctgtcct cattccacta gcactggggt ttatattggt
    15601 tattggggga ctattggttg ctttactagc gctcattttt agtatctatg ttttatgtat
    15661 cagtatctta ggtgttggcc tattcatgat catatcagga ataagtgtgt ttggacaatc
    15721 gattctgagt ggattattct ttatcggtgt cggtctgttc gccacaggaa gcgcagtatt
    15781 tatttcgcca ctgttgctga aaggaacaaa agggcttttt tatgtcatga tgaactttgt
    15841 taaatggatg ggacgacgtt ttattacaaa aagagatctg cattcagcgg gcgtttgaag
    15901 gaggacacat aaattgagat tgaaacattt tttgattacc ggtattggtc tgatgcttac
    15961 tggtggcctc ctagcaggtg caacttatac attaggcgct caaaagagtc tgacttggga
    16021 taatggtcct cggttgatcg atatggttac tgagacaaaa aaaatcaagg atgcaaacaa
    16081 aatcgtcatc catgcagaaa atcaaacagt ttcggtcata cgcggattgg attttgagat
    16141 aaaaacgact tatgataaga cagaaaagcc agaaataaag gagaaaaatg gcgtgttgac
    16201 tgtgaatgca gtcaaaaaat caacaggtgc aatcattagt ttagaagaca caagtgcaca
    16261 aatcactatt gttgtccctg cagattatga attatctgaa ttgacaatcg aagggaataa
    16321 tagtgcaatt gatatcaacg aagtatcaat caaaaaagtg aatactaaga cacatgatgg
    16381 ctgggtatcg ttcaatgaat ttacaggagg aacaataact gcgaaagatg aattaggctc
    16441 acttcgacta gatgaggcca atgtggataa cttgatcgtc acaggtgaaa acagcaactt
    16501 ccatctagaa gacagtttga tcagcaaaga aggaaaagtc atcctaaacg gtggtaattt
    16561 atctttgcat gagatggaaa acagtggcta tactatccaa acgtctggtg aatcttatat
    16621 tgaaaaagac taccagccaa taacaaatac tttgttagaa caaggacaga aaaagctaaa
    16681 gatcactgct aaagacacat cgatcaatat tacgacggat caagaggaca atgaaacaga
    16741 ttgatcctgt actcaactag atattttaag aaaaaacagc aaagatcctt ccaatctttg
    16801 ctgtttttca tcgcttaacg cacataacta tagtaaaata agaaagaaaa tatctataaa
    16861 gaaaacaggg tgaaaaagta tatgaaggca gaagaaggtc aaagagaaaa gttaaagaca
    16921 gaaatggaaa gattacatac ttatatcact caactaagcc aaaccttcta tgatccagac
    16981 aaagaaaaag tgatggttaa ttacccgaac aattcagaag gtcgccaatt agagcaagtg
    17041 taccatgaag ttttcaaaca tttattgacg gtgaagaaag agctggatta ttattcttta
    17101 ccgattatcg atacaggaat attgaagtat gatgggaaga aggaacgatt tatctttaaa
    17161 tctgttcggg aagatttgcc tctttcagca gggatggatc tagaggtctt ggtagaagac
    17221 tattttacag aagaaaagca ctgggttcga acaaaattgg attatttacc gcaggcagcc
    17281 ggagggacac aggcaagcgg ttggtacatc actgaagaca aagagttaga actagaaggt
    17341 gtaatggcgc gtattcgaaa aaaaaattaa aaaagtaaca ttagatattt attgaaggat
    17401 aaaggagcgc aggaagtagc atgagagaaa aaagagcatt ttatatcaat ggttatgcag
    17461 ggattgtcgg attgatcgta ttagctttag ttggattgtt tttcttctat ttaggcatgt
    17521 ggcaagcgaa agtttgggca ctttttttaa gtatttttct ttggttgatc acgttattgt
    17581 tgttaagttc ggcaactgta gtcagtccta atcaagcaaa agtaattttg ttttttggac
    17641 aatatttagg tacgattcga gaaaatggct ttttccttac gatacctttg gcacaaaaaa
    17701 tgactgtttc gttgaaagtt cggaatttca atagttctgt tttaaaagtc aatgatttgg
    17761 atggaaaccc catcgaaatc tcagcagtag tagtctttaa agtcgttgat acagcaaagg
    17821 cattattcga tgtagcgtat tatcaagatt ttgtagaaat ccaaagtgag acagccattc
    17881 ggcatatcgc tagccaatac ccgtatgata cattcaatga gaatgatttg acgcttcgag
    17941 gaaacacgac ggcagtgtct gacgagttgc aaaaagaact gcaagagcgt ttagcagtag
    18001 caggtgtcga agtaatcgaa acacgcttga accatttagc ctatgcaaca gaaatcgcta
    18061 gtgccatgct ccaacgtcaa caagcaaaag ccattttgtc tgctcgacaa accattgttg
    18121 aaggagctgt cacaatcact caaatggcct tagagcaaat cgaagatgga caagaaatca
    18181 atttcaccga tgatcggaaa gtccaattga tcaataattt acttgtctca atcattacag
    18241 acaaaggaac gcaacctgtt atcaatacag gcgacatgaa agaccgtaag tgacatactt
    18301 tttgtaagat aggaagaagg agtttaggac ggattattgt cttgaactct ttttttagtt
    18361 gttttaaaga aaatgacaaa attgaaagaa gaatgatagt tgattcgaag gcagaattgt
    18421 tcgctttttt ctataatcag tatataaagt aagagagaag gggaaaaagt gaaaaaactt
    18481 ctgatcggtc tacttgtttt catcgttgtg gtacttgcag gggtgaaaat cgcagattac
    18541 gtagttatgg gtggagaaga atactatgta caaattacga cagatggtac aaaaacagtt
    18601 tcaaaatcag actctggaca agaaacagtc aactatagat atatcctgcc tggctatacg
    18661 aaagagggta aggaaaaaga actggacttc aagggacaat tgactcgacc gcttcgtaaa
    18721 ggagcatatt taaaaatcac ctggaacaaa aataaaggtg tcacttcgta tgaagaagtc
    18781 gaaaaaaaag acgtgccgaa aacagcactg gaaaaactaa ttaaagggta gggaaagaaa
    18841 tgaacaaaat agtcgaagta cagaatgtaa caaaagtata cggaaaaaac aatgagaaaa
    18901 agacgcaagc attaagcggc atcagcttcg atgtagaaaa aggcgaattt attgggatca
    18961 tgggcgcttc tggttctggt aaatcgacac ttttgaatat tttatccaca ttagataaac
    19021 caacagatgg gcatatccga atcaatcaaa aagatgtgac cacattaaaa ggaaatcaac
    19081 tagcagattt tcgtgcgaat gagattggct ttattttcca agactttaat ttattagaaa
    19141 gcttgacagc acaagaaaat atcgctgttc ctctttcttt acaaggcgtc agaccaaaag
    19201 aaatcaagca acgtgtccaa aaaattgcag aacgtttatc catctctcat attttggaaa
    19261 gctatccttc tgagatttcc ggtggacaaa aacaacgggt cgccgccgca cgtgcattga
    19321 tcacacaacc aacgattcta ttaggggatg agcctacagg tgcgctggat tccaaaagtg
    19381 cccgggatct tttagatacg atggacgaat tgaatacaaa agatcatgta tcgattcttc
    19441 ttgtgacgca tgatccgttt tctgcaagtt attgccaacg tattttattc atcaaggatg
    19501 gcggtatcca tcaagaagtg aaacgtggag atcaaagccg tgattccttc tatcgagaaa
    19561 tactatctat tcttggaaac ttggaacagt agggggagat tgactatgct ttggaaatta
    19621 tcacttactg ggatcaagag ccgtttaaga gactacttgg tgttattctc aggattagtt
    19681 atggcatctg ctatttttta catgtttgaa tcaatggcaa gcaacgaagc ttttttgaaa
    19741 agtaatacga tcgttgcggc tacagttatc attttccgat tcggttctgt tttactaggg
    19801 atcatcacat tcgtttatat tttatatgca aattcctttt tgatgacgat gcggcaaaaa
    19861 gactatgcaa tgtttatgat gctaggagca aaaggcagaa aaatcgcaca gatgattttt
    19921 tctgaaacat tcttagtagg gatcgcagct actttagtgg gttcagctgt cggtgtagga
    19981 ttgacaagta tcgtccaccg attattagtg gatcagttag atctcaatat ttcgcatttt
    20041 acacctttta gtattcacgg gttgttgatc actgttttgt tttttgctgt tttgttttta
    20101 ttagctgctg ttgtcaatgc tttttcgatt gtcaaaaaac cgattttagc attgattcgt
    20161 gcggatcaga caccaacaag aatcaagcag cataaattct tgtttttcct tgaagtagta
    20221 ctgggaattg cttttctagg ctgcggttac tatatgatga aacacgtggg gacctatcaa
    20281 gtctttggta taggagtagc cttagttacg atcgtattag gaacttattt cattttccat
    20341 tctgtgatca ttttcttttt atcattacta aagaaatcag aacagatttc attgaaaaaa
    20401 ttgaacaatt tcacattgtc acagttaaac tttcgtattc gtgaatatac acaaatgctc
    20461 tcaatggtcg ctatgctgtt tgccttggca ctgggcgctt tgacggtagg attaggtttt
    20521 aaaaatgaaa ttgcagactt gacagaaaac aattctggat atgatctagt gatgaataat
    20581 cctcgggcag aagatcagca aaaaatcaaa gaactttcac caacactttc tgcttcttat
    20641 actcaaaaag aagatgcggg aacgatttac tataatgcaa gtgaatttgc ggctcaacca
    20701 ttgatcatga taaaacatga agatggaaca ccgccgaaga tcacgaaaga aaaagttcct
    20761 gctgaaaaaa tgaatgaact gactgtacaa gaggaacttc gaagctatga attgccggaa
    20821 cagcaagaaa aagaaatcaa ggtagtcagt caatcagaat ttgatcaact gaacttgcca
    20881 caaaccactt tacagctagt tcaggtaaaa gacttccaag caaacctgaa accaatcgaa
    20941 acacttgttg ctcaaaataa aatgaacaat ccatctttgc aaaaagtaga gtacagcaac
    21001 cagaaatatg aaatgtatga agtgtataat ggtctattct ctggttttga atttatggga
    21061 ttcttcctag gtttagcttt cttgaccatg cttgctagct gtttgatgtt caagatcttg
    21121 tcaggaagca agagtgacat tgctcgttat gaaatgcttg aaaagatagg aacacgacgc
    21181 gggttgctta aacaatcgat ccgtagagaa gtaggcgtgt tattcttagc accaggaatc
    21241 ttaggtgtag tccatgtctt attcggatta caaatgtttg gtctattcat gcaaaatcca
    21301 tacaaagata tttgggttcc gtttacgatc ttcttcgtat tgtatttcat ctactatgta
    21361 ctgacgacat ggttatatac tggaatcgta ttgaaaaaga gattgtgaaa aagctgtcct
    21421 gcatcaagta ataagaacag ccaagcaaaa atagctcctc atatttttcg tttgattggg
    21481 cttattaccg cagatgcaag cttttgaaca ccgtttgttc ggaaaaagag gttgtgacaa
    21541 tacttttgtc acaacctttt ttcgcggtct tttattagaa tatagtaaat tttttctcgt
    21601 tactcacgga ataagctgtt aagaaaacgg tttctatgta tactggaatc agtgcaaatg
    21661 aaagaaaaga gggtgcaagg aacatggaaa tcaatgaaca aaattttggc gaaaactatc
    21721 acttgattac tatcacgaat caaaatggga catctttgtc tgtcagtgat cttggggcac
    21781 gggttgttca ttttcaaaca ataatcgata atgaaaaacg agagttgatc ttaggttttg
    21841 atgaagcaaa agaatatcta gaaaaagacc cttatatcgg tgcttcaatc ggacgtatgg
    21901 ctggacggat cacgaatggc acattcaaat tagatgatga aacgttcgaa gtaaaaacag
    21961 acccggacac tggtcattgt ttacatggtg gtgcacctag ctttgaagcc aagcagtggc
    22021 attatacagt catcaatggt gaaaacgaag catcggttat tttctatcag actagcccag
    22081 acatggaaaa cggatttcct ggaactttag atgtagaagt acggtatacg ctgacgaacg
    22141 atgatacatg gcgagtgacg gtccaaggga tcagtgaccg caaaacagta ttcaatccta
    22201 caaatcatgt ctatttcaat ttaaccggtg atccagcaca gtcaatcgac gaacatatac
    22261 tttggttgaa tagccgatta tttgctacgc tcaataaaga tacaacgcct acaggagaag
    22321 tagtttcagt aagtggcaca gcatttgact tccaacgtcc taaaaaatta ggtgaggtct
    22381 ttgccagtga ttttcgccaa tcaatgatag tgggcggtat cgatcatcca tttttgttga
    22441 aaaaacaatc tggtttacta aatgctgcgg aattgacaag cctagatgaa aaagtatcga
    22501 tccaagtaaa aacagatgct tcaggaatcg tgatttttac agcaaatttt ggagaagatg
    22561 gaccggaaat gcgcgggaat aaattagtaa atcatggcgg tatcacattt gagactcaag
    22621 aactgccagg agcggagcga cttgaaagtt ttggagatgt cactctggaa cctaatcaag
    22681 tacgcgagtt tgtaacggaa tacaaaataa atataaagaa atagaataaa ttaaaaaggg
    22741 agtgtgacag tgtcacatcc cctttttaat ttattctatt tctttaaagg cagatcaagc
    22801 cagaatgatt tgtctaaact taacaaggtt agtacaggaa cagttgcagc tttaactgta
    22861 cgagtagttg tttctggtat ctgtcttgcc gtaaaattgt tccacaaatc ccagattgaa
    22921 gcgacacgga agatggaaga agcgttgttg acgcgtttta tcgttgaaaa ttctaatcct
    22981 gtgattggca cgccatctgt tgtccatttg attggcacat cgaatcgctt agacatattg
    23041 aggatttcgg cgtttgcttc ttcagttgtt gctgcttctt ttttcggttc atcatatttt
    23101 gtcaggtcgt acgcttcgat gatcgcgttc aatttttgtg aatattggcg atctgtagca
    23161 taacgtcctt ccaaatattt ggttgcttct ttgtagtctt ttgtttccga cttccaagtt
    23221 ggtttgtaga aatcaggatt gccagtcagt ccatttttga tcaagtcggc atagtcttcc
    23281 aaactttcct tgtaagaagg atatttacgg aattgtgcgc ggatttggta gctttgtccg
    23341 gaactatctt gttcatgtgt attgaaggtc acgctgcttc cattatatga tcctttgata
    23401 ccaaaaaggt tatgatttgg ttcgcttgat aataagctgt ttccagatcc actttcaagg
    23461 atagcttgag ccatcatgac tgatgcgtag attccttctt tttgcccgat ttcctgtgca
    23521 tcatctgcaa tctttttcaa gaactgatca gttgtttggt tttgactgaa atggaacgag
    23581 ccatctaatc catctaaaat agatgaacca gttagcgagc ctgaagtagc aggtaaacct
    23641 gctaagttta ctcggacagc aaaatcaggc gtgaaatctg aaatagaagt tactcgaact
    23701 ttatctcctg gttggggcgc atggataaat tgtccgttcc caatatagat acctacatgg
    23761 tgagtaacac cggaagaagg tccccagaag acgagatcgc caggttgggc ctgacttact
    23821 ggaatctgcg tacctgcata ttgctgttcg cctgtccagc caccgatata atgaccggtt
    23881 gctttcatat atacgtaata agtcaaacca gaacagtcaa aagtatttgg acctttggct
    23941 ccccatacat atggttttcc aagatgctcg aatgcttctc gaacgattgc ttgttggaca
    24001 ttcgttgtat ttgtaggcaa tacagcatca attggtgatt ttacaacaaa atcagaagaa
    24061 gcagaagatg gattctctat accgctttga tttgctgtat ttggacgaga tgaagcattg
    24121 ttcgttccgc cattcgatga accattgttt ggatggtttg gttctctctg agtatttcca
    24181 ttgttattcg atccagatgg gtttgtttga ttcgaagaat tcccgttgtt cgaattattg
    24241 ttattattgt ttgaattatt tgaaccatta ttattgttgt tattgttgtt attacccaca
    24301 tctggtttgt ttggcgtttc cggatctggt gtactaggga cttcttcact aggatcagtt
    24361 ggtttctctg ttgaagtatc cggtacaggt tcaaattctg cagtaataga taaattgttc
    24421 gtacctactg taaaggtctt tgcatcataa tttacttctt tggcaccatt aacagcgact
    24481 gaagcaattt gttcaccttc agctggcgta atagtgtaag ttaccttcgt ttccgctaat
    24541 aaaccttcta ccgttccact ttccgtaata tccaaaggtt gctgttcagg ggaatccgct
    24601 gtcgaagcag tcagttggat cttaccaatc aaagaaggag caattgtaag ggaatatgtc
    24661 tcggctggct tttcattttc tgatggatca gccggatcaa tttcagttgg ctcggtcgat
    24721 cctgttgttg agttagttgt tccagttggg tcttctgtaa aagaatccgt tgtttcacta
    24781 gtagctgagc tggatgtagt cgtatctgtt gtgactgttt gatctgctgt ttgattatct
    24841 acggcaaata cggtattggt cgacaaaacg gacggagcaa tcagccaagt agcagctagc
    24901 aaacgtatcg tttttttatt tttcataata aactagtcct tttcctttca ttgattttct
    24961 gtcttattca gcattcatta gacatttttt ggaacagata atcgtgtcga aaagcttttt
    25021 cttttcataa atctgtctgt gtattctaaa taaaacaatt tgtaaataag caacgagcat
    25081 tcattcgttt ttctttgacg ttcattttat tgcatagacc acctttgttt ggggataaac
    25141 aagtggggat aaaaatggtt atgcatatgt aaattatacc aaagtttgga aagtatcaca
    25201 aaaatttata aaaataatga tcctaaaaag aaaaagactg aaatatgtga taaacatctc
    25261 atacttcagt ctttttcatt aactattcat aagacattag gtcttcatca aacccgctaa
    25321 cgagagtagt aatcattgct acgactagac taacagccag tcctgctaag taccagaaaa
    25381 aagtaccgga aatgaatgca ggcaatgtgg tcagactacc aaatacaaaa gcgatcgctt
    25441 tcacttgggc aaatcccatt acagctccac cagcagctgc accaatgcaa gcagcaacaa
    25501 atggtttttt caatgggatc gcaattccgt aaacagttgg ttcggtcact cccgcaagta
    25561 aaatcgaagc aaaagcagaa ccggagatcg aacgagtttt tgaacgttta cttcgtagaa
    25621 atacacctaa agctgcacca gccattccaa aattggctgc tcctgtcaac ggaacgattc
    25681 ggtcgaaccc ataagcagag atattactga tcatgacagg gtttacagcc cattggatac
    25741 caaatattac caaaatattc caaccaccag cgatgattgc gccgctgatc ggtccgttaa
    25801 tatccatcat ccaagtaatt gcggcagcta aaccttcgcc aaggtaaaca cccgcaggcc
    25861 cgaataccat taacgtcaaa ggaaccgtga taactaatga aagtaaaggt acaaatacta
    25921 attgcatatt atcgcgaata tattttttga ggaatttttc aacaaaagaa taaaagaaaa
    25981 tacctaaaat cgccggcatg acagtagacg tatactgcat cagtactaca ggaatcccca
    26041 gaaaatcagt agctgctttg ccactgtctg aaagtaaaga ggtcagattc ggttcaatca
    26101 gtgctgcagc aatgacagcc gcaatatatc cattcacttt aaacgttttg gcggcagaaa
    26161 aagcaagaaa gattggcaga aaataaaaga cggcattcga cgcagcagac aaaatatgat
    26221 aagttccgct tgtttcacta agccagccaa tcgtagtcgc taaaacaacc agacctttta
    26281 atataccaga accggcaaac agcggaatga tcggcgtaaa gatttccgat atcaaaccaa
    26341 atagtttttc gatcggattt agcttttctt tcggagctga atgatcgatt tgacgcgtca
    26401 attccttgta agcaggagcc aatccctgat ccatgattat ttctgcatat ctatcgagta
    26461 aaatgaaata cttaatggaa gggatttgct gttttaattt ttctgcattg gctactggct
    26521 gttttttcaa tttgatacga agccgagtcg cacatggaag gacagaatca atattgtctt
    26581 ttcctcccaa ctgttcaatc agcatatgaa tctgctcgta cagtaccatc tgttcaggat
    26641 tcattgtcgt ttccattaga agaccactcc actcactaat ataatattgg cgtaaggtgt
    26701 catttcgcct gtacgaataa atgcatgaca gttattcaac tcttttttca tttcttcatg
    26761 tgggataaag ctaatcggtg tatctggtaa caataatttg attttttcca atatttccgg
    26821 attcattgtc tttatttctt ccgccaattc aatcgattgt acctcaagtt cttctaaaac
    26881 gttttctaaa acagataaaa agcttggaag accgtttgag acagccaaat ctattttttc
    26941 agtaccaaag gggacaggca tgcctgcatc cccgatactt aatttatcaa agtgccccat
    27001 ttgtgcgatt actcgtgaaa tatctgaatt gattactttt ccttttttca tgtttgtttc
    27061 ttcctctcat tgttaatttt agactgctga ttgttctaaa gcttcgcggt aagggataga
    27121 aggttgcgca ccataagact gcacagcaac agaagaggct agatttccat aaaggatcgc
    27181 ttctttcaag ttactaaggt ctggctgaag tgtgctgctt aatgcgccaa taaatgtatc
    27241 acctgcggct gttgtgtcaa cggcatccac tttaaaagca gggacgatac cgtgttcttt
    27301 ttctgtatga tagaaagcgc cggcactgcc tagtgtaatg attactgttc caatacctaa
    27361 ttcatggagt ttttcggctg ctgcgaccaa actgttatga tctgtcactc tgattcctgt
    27421 aatgatttct gtttctgttt catttggtat aatgatatct gtcttttcaa gtagttcagt
    27481 aggaatcgtt tcacgagctg gtgcaggatt caggatcgtt gtttttcctg cgtcttttgc
    27541 aatagaaaaa gctaggatcg tcgcatctaa gctactttca aactgagcaa taataaagtc
    27601 actgtttgta atcagttgct tgttttttag gacttcttgt tcatggaaag cattatttgc
    27661 ccctgcatgg atcaagatac tattttctcc tgctgcgtct accataatca ttgcttgtcc
    27721 ggttgtggcg ccttggattt cagctatccc agatgtatcg atgttttctt ttgtcagtag
    27781 atctaataac tgttgtcctt cgctgtcagc cccaacgcct ccaataaaag atgtccgtgc
    27841 gcctgaacgt ttggctgcca ctgcttggtt ggcgccttta cctccgccag cgtgaaaaat
    27901 ctcatgcgca tgcatcgttt cgcctggctt gggcatgttg gttaaacgaa gggtagtgtc
    27961 catattaata cttccaatta ctgtaaccgt gttcatttta caaacctcca actatctcat
    28021 ttattttgat gggaaaaatt attttttaaa acgttttagt aaaacgtttt aatagttcga
    28081 taaaaatata gcacaccttg aaagctattt caagggtgca gttgaaaatc ttttttctaa
    28141 tcgtacaggt aatctttttt cttcccattc tttttctggg aattggatcc gatctaacaa
    28201 taatttggca gatgtttgtc ccaattcgaa gatcggttgt gcgatcgttg tcagtttcgg
    28261 cttgatatac tcgcacatat ctatattatc atagccaata atgctgtagt cttcagggat
    28321 gctttttcca gattcctcta atccgcgata taatccaaaa gctaattcat catttaaagc
    28381 aaacacacca gttgcagcag aatcaagaag ttctgctgtg atttggtagc caccttgttt
    28441 tgagaactgt gtaggtaaga ggatcagttg gtcgtgagag atttggtaaa catcaagagc
    28501 agatttaaac ccctcaatcc gagcgtggac attttccggc ggattttcag gatagacaag
    28561 ggcgatcgtt tgatgaccta gactaagcaa gtgcatgccc gctaggtaac caccgcgaaa
    28621 atcgtctgtt cgtacggcat cactaaatcc ttcagatttt ttctgatcca aaacaatgaa
    28681 gggccggcct tgttttttca aattttcgtt gattgcatct gtagagacag cagaagtcgc
    28741 gataatgaat ccatccacac ctcgacgtgt gagctcggct agatattcga tttctttttg
    28801 atgatcagaa tcagcattac ataatatcgt gacgaaattc tgcttataca agatatcctc
    28861 aattcctcgc atcagtgtac tgaagaatgg attcgtgata tcaggaacga gtacaccaat
    28921 tgttttcgtt tccttggtaa tcatttgtct agcaaaatag tcaggctgat agcctaattc
    28981 ttctttggca gctaaaactt tctgaacagt tttcggactg aatttctccg tatttccatt
    29041 taatatcaag gagacagttg tgattgaaac gccggaaagt ttagcgactt ctttgattgt
    29101 gatctttttt ttcaccatgt tcatactcct atctaaatcc tgtggttatt ttcccatgaa
    29161 atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt atttgctttg ttggatagct
    29221 tcgattattt gtttcgttga gcgtactcgt gcagttttcg gaaatatctt ttttatgaac
    29281 aattgatggg attctttgtc acgatcactg caagcatctt cagcaagtac gacatgatac
    29341 ccatgttgga aggcatctaa tgcagtagca tatacaccgt ttgttgtcgc tacaccgctt
    29401 aaaatgatag tttcgattcc acgccggcga agttgaagat caagagaagt accaaaaaag
    29461 gcacttggat tgtattttgt gatagtcaac atattgtttg tatctttcaa ggaatccttc
    29521 aacaacaagt cagtgaattc tggaggtaca gaagcagtca ttccacccat atcagtttgt
    29581 tgactcaaat aagggaaagt ggagatgtct acgttcacta aaactttcaa ggcagcggta
    29641 cgtttcaatg ttcttactaa caaatcattg tttgacagaa tagattgtgc agtgtgtgga
    29701 gagagtgtac cgttatttac gatccctttt tgcatgtcga tcgcgacaaa agcagttttt
    29761 gataaatcaa aaatcatatt ttcctttaaa tcattcatga tgttccttct ttcaaataac
    29821 aatgtttttt atgtaagtaa atcataaatc gtttatttgt caactaaata aaggattcct
    29881 ttctttagtc tagagaaatt cagtggtaaa ataaataagt gtgagaaaac gcattctatg
    29941 catagatata gcgagaaata tcgtgaaaat ggaggaatca gagtgaagta tgtcgaagta
    30001 aaaaatgaat acaaacgata caaaatggga gaaacgacca ttacagcaaa tgacgatatt
    30061 tctttttcaa ttgaaaaagg cgaattagtg attatacttg gtccaagtgg agcaggaaag
    30121 tcaacgattc ttaatatttt aggtgggatg gatacacctg atgaaggtca gatcattatt
    30181 gatgacacag atattgcgca attttcagat aaacagctta ctgcttaccg acgaacagat
    30241 gtagggttcg ttttccaatt ctacaatctc gttcctaatc taacagcaaa agaaaatgtg
    30301 gaattggcaa cggaagtttc tcctgatgcg cttgatcctg tagaggtatt gaggcaagtg
    30361 ggcctagctc atcgattgaa taactttccg tcccaattat caggaggcga acagcagagg
    30421 gtttcaattg ctcgtgcact agctaaaaat cccaaacttc ttttatgtga tgaaccgaca
    30481 ggcgcgctgg attttgaaac gggcaagcaa gtattgaaat tattgcaaaa cgctagcaga
    30541 caacacggca ataccgtttt gatcattaca cataattctg ctttagcgcc catcgctgat
    30601 agagtcattc acattaatga tgctaaagta aggtctgttg aattaaatga tcatccttca
    30661 tccattgatg agattgtatg gtagggggat tttatgaaaa caagaacata tcttaaagca
    30721 ggttttcgcg aaattcggca atctaaagga cgattcattg caatcatcct tattgtcatg
    30781 ctaggaacac ttttatttgt aggtgtcaaa actgctggac ctgtcatgca aaaaacgatg
    30841 gatcactatg ttggtacagc aggactttct gatttgcaaa tcgtttctac tggtggcttg
    30901 acacaaaaag atattgctca agcagaaaag atcccagatg caaaagtaga aacaggaaaa
    30961 cagatctatt attccaatac tggcaaaaac gaagtgattc aaatattttc ttataacaaa
    31021 aataacaagc agaacaagct acaattaact gatggaaaac tcccggaaaa accaaaccag
    31081 cttgtattgg atgaaaaagc ggaagatgaa gggtataaaa tcggtgatat ttatcagatt
    31141 gattcagatg aattgaaaga aaaagagtat accatcacgg gctttgtccg ttctccattg
    31201 ttcatcaaca atttggagag aggatacgcg aacgtcggaa atggtagcgt cgattatttt
    31261 gtctatttac ctgaatccgt ttttaaaaca gatatttatt ctgtcttata tcttgatttt
    31321 acaaacgcaa agaatttgaa tacgtacagc aaagcttaca aagataaaat ggagcaaaat
    31381 caagaaaagg cagaaaagta tttacaagat cgacccgaag aacgcttaga agagctgaaa
    31441 aaatcggcca acgaagaatt agaaccggca cagcaaaaaa tagcggatgg caaagcacaa
    31501 acaacgcaag caagaacacg gttagaagat gctaaaaaac agttagcgca acagtcagca
    31561 actatccagc agcttcctga agcgcaacga acaatcgctg ttcaaacatt atctcaacaa
    31621 gaagctcaac ttgctgaaca agaaaggcaa ttagttgaga aagaacgtga actggcctct
    31681 gcagaggaag aattgaatcg aaatgcagaa aaaattgaaa atttaactaa accatcatac
    31741 ctatacaatg aacgttcaga aaatgtcggt tttcaagaat ttggtgatct gtctgatcgt
    31801 atcgctgcga ttgccaatgt ttttcctgtt ttctttttct ttattgctgc attgatcacc
    31861 tttacgacaa tgacacgtat ggtagaagaa aaccgcaggg aaatcgggac attaaaggcg
    31921 ttaggttata cgaaagttga aatcgcaaaa aaatatgcaa tctatgcaag tctagcctca
    31981 gggataggca ttgttttagg aacgatatta ggaacgaatc ttttgccaag gatcattttt
    32041 gagctgtcta acgagcggta tgatattggg agtgcgctta ttttttatga ctggccgccg
    32101 attttacaag cagctgccgc attcttcatt gccgcatttg gcgctgcaat gatcgtttta
    32161 ttcaaagatt taagagaacg gcctgctgca ttgcttcaac cgaaagcacc gaagccaggg
    32221 aaacgcattt ttcttgaata catcactccg ctgtggtcac gccttagctt taatcaaaaa
    32281 atcagttacc gaaatctctt ccgatataag tcaagaatgc ttatggcgat tatcggaatt
    32341 gctggatgtg ccgggctgat ggttgcaggc gtgggattga aagattctct aagttctgtc
    32401 tcagccaaac aatttggacc gatcattgac tatcaagcaa tcgttacatt ggattcatcc
    32461 acggaagata gtcgtcaaaa agcagcggat atgctgcaga agcaagaaaa agtaaatgag
    32521 atcctagcta ttcatactca aaccgtagaa ttgagaaaaa aaggacatgc ttcgcaaagt
    32581 ctgacagtga tcgtaccaag taaaacagct gatttggatc gttttatcca tttaactgat
    32641 cttgaagaga acccacgctc cttgcctaaa acaggaatcg ctattacgca aaaagcagca
    32701 gaactatttg acttatctac aggagatcat atttcgcttt atgatgaaga tcaaaaagaa
    32761 tggaaagtcg aagtaaaaga aatcgtgaaa aactatctag gtagctttat ttatatgtcc
    32821 cctgaatatt atgcttcagt tactgatcaa tcgatgatgg ataatgcatt tttgctgcgt
    32881 acagataaga tgacaacaaa agaagaagaa atgctttccg agaaactgct tgccacagac
    32941 gctgtgacaa atacgtcttt catgtccaaa caaatcgaaa cgcaagaaga atcaatggcg
    33001 aacttagact cggttgtctt aatctttgtc gtattatcag gactgctggc ttttatcgtc
    33061 ttgtataatc taactaatat caatatttcc gagcgtgtac gcgaattatc tacaataaaa
    33121 gtccttggat tttttgataa agaagtcacg atgtacattg ttcgagaaaa tatcatcttt
    33181 actcttttag gaatcatcgg aggatttggt gtaggatata tattgactga cttcatcttg
    33241 caacaagcgt ctatggagaa tgtcatcttt ccattagtga tcacatggtg ggcttatgtc
    33301 ttatcagcag gattaactat cgtattcacg gttattgtga tgatcgttac ccatttcaaa
    33361 ttaaagcata tcgatatgat tgatgcgttg aaatcgaatg aataaaaaca gaggttgtga
    33421 aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagcttc tcatattttt
    33481 cgtttgattg ggcgtattac cgcagatgca agcttttaaa caccgcttaa ggaagaggtt
    33541 gtgaaatcag cgttttgagc taataacgag ggtcagctgc taattgaaca ccgtgaatca
    33601 gaggttgtga aaaagctgtc ctgcatcgag caaaaagaat actcaaataa aattagctcc
    33661 tcatgtttta catttgagaa gactgattgc cgtagataaa agcttttgag caccatttat
    33721 agaagaaaca agaatatttt gctattttaa acaagaggat agacaaatac atgtctgatc
    33781 tcttgttttt tattgggcaa cagacctctt agaatgtata aagataaatt ttacaaacgc
    33841 tttcggttca gttataataa taaatgataa cttgtatata taagttttgg taggtaataa
    33901 atcagttgaa tggaggtaaa tatccatgac atttaaagac aaagtcattt accaaatcta
    33961 tcccaaatct tacaaagaca gtaatggtga tggaattgga gatttaaaag gaatcaaaga
    34021 aaaactcccg tatctgaatg atctaggcat cgacatgatt tggctaaacc ctatttatcc
    34081 aagccctcaa aaagacaacg gttatgatat ctctgattac acagccatcg atcctatctt
    34141 tggtacgatg gaggaattcg aacagctaat agccgaagca aagaaatacc ggatagaaat
    34201 catgctcgat atggtgctga atcacgtttc gacagaacat gaatggttca aaaaagcact
    34261 agcaggggac cagcattatc aggacttctt cattttaaga gaagagccaa cggattgggt
    34321 atcaaaattt ggtggaagtg cttggtcgcc atttggagat acggggaaat attatttgca
    34381 cttatatgat cggacacaag ctgacttgaa ctggcggaac caagcagtaa gagaggaact
    34441 attcaaagtt gttcgttttt ggatggaaaa aggggtaaaa ggattccgtt tcgatgttat
    34501 caatgttatc ggtaaagacg aacaattgaa aaataataaa gaaaatgatg gcaaacctga
    34561 atatacggac aaaccaatca cccatacgta tctaaaagaa ttgaaccaag caacgtttgg
    34621 gacggattcc actatcatca cagtcggtga aatgagctct acgacgatcg aaaattgtat
    34681 cttgtataca gaacctagta gagaagaatt atcaatggtc tttaatttcc atcatttgaa
    34741 agtcgattat gaaaatggga ataaatggtc tactcctcca tttgattttg cagaattaaa
    34801 gcgactattt catacatggg gagaaaagat gagtgagggt aacggctgga atgctctatt
    34861 ttttaataat catgatcagc cacgtgcgct caatcgattt gtagctatcg atcagtatcg
    34921 aaaacaagga gcagagatgc tagcaaccat gatccatttg aaccgtggga cgccctatat
    34981 ttatatggga gaagaaatcg gcatgatcga cccagactat tcatcgattt ccgactatat
    35041 tgacgtagaa agtttgaatg cttataagtt actccttgaa caaggattca cagaaaaaga
    35101 agcgtttcgt cggatcaaag caaaatctcg cgataactct cgaacaccca tgcaatggtc
    35161 agacacagaa caagcaggat ttactacagg gaaaccttgg ttaaaagttg gaggcaagct
    35221 agaagagatt aatgtagaaa aagaactatc ttctgaagat tctattttgt cctattacaa
    35281 gaaattgatt cggctgagaa aaacatatcc aatcgttgca caaggagatt atcatgctta
    35341 tgaagcaaat catccggaag tttatggctt tcttcgccaa tttgaaggac agcagctgct
    35401 tgtattaaca aatttctatg ataaagatac aaggatcgcc atcccagaag gattcacaga
    35461 agccaatatt cttatcgata attattccga tactgttctt catcaaagtc tggagctaaa
    35521 accataccag gcaattgctt tgctgaaaaa ttaaaacaaa aacacaaaac gtcgttccta
    35581 cgagctattc tcgtaagatc gacgttttgt gttttattta aaataatctt cttcagaaaa
    35641 tgaagagttt tgatactctc ctttatcgcc ataaaattta ttgtagcgtt gtttgaattt
    35701 acggaaaata aaagtaacga gtaatttgac taacgtatag ataggaatac caaaaataac
    35761 gcccacaatt cccattagat cacccatgac aagtaaaacg attaagatcg taatcggatg
    35821 gatctgtaaa cgatcaccca ttactcgagg aatcaccaag tcaccgtgga gaagttgtac
    35881 ggcaaaccag acaatgacaa atttgacagc cataaaagta gagtcttgga atgcaatgat
    35941 caaacctgga aagaaggcga taaacggccc aatatatgga atgatacata acaacccagc
    36001 agaaatagct aaaacactag caaattctaa tccgatcagt aagaaacaaa cccagtagac
    36061 tgctccaagg ataaatgaag caatgatttg cccctttaga aatgaaccca attgttgatt
    36121 agcaatcttt gtcaaatttt taaaatctgt acgaaatgct ggtgggacaa tcgctaaaac
    36181 tgactgataa aatttttgag gatctctcaa aaggaaaaaa gcgacaattg gaccagtaaa
    36241 taaagtaata aaaatagctg taacagttga aaaaatgttg ctgatccgtt gtgcgccact
    36301 ttcccaataa tttccaataa atccagctat atcagacgtc acgtcgtcaa tagaagcgaa
    36361 aaattgatta aatgaatcgg caaaaggtgt tttctccaaa aattgtcgga gactctcttg
    36421 aaaatcttga aacaaatctg gcaaactact gatcaatgtc tttgcctgtt cttcaagaaa
    36481 aggaacaagc catacgcttc caagccccaa taaaaataaa ataatcacat aaacgataat
    36541 gactgacaag ttcctcgaaa ggtgcttgct caaacgtttg atgactggtt ccaaaagata
    36601 atacaagatc agtgcaaaca ataatggggg caagatagta gcgataatga ttccgacagg
    36661 cttgaatata aacgagatct gatggaaaaa ataaatgatc agcgcaagta agataactat
    36721 tcctaaaaca tagtaagagg tttttcctcc taaaaagcgg atcaaacgat tcgttgtatc
    36781 tgtttctttt ttcaatcttt ttcctccttt atctataact tcattataga caaaagcggg
    36841 tataaaagga aaatgataga ggttgattgc aaaaatatcg tcaatcattc acataaactt
    36901 tctcatcaat taaaataaga aaacgcttga cagttatttt aaccatatga taaattaaat
    36961 cctgttgcta aaacgtaact attacggttt acaaaaggcg aatcggaaca ttcaaatgaa
    37021 agaagatgag aagaggagtg tcataaatga aacgattgat aggtatattg gccatgctgg
    37081 ttttagcagg tatgttaact gcttgcgggg caagtgggaa agccgaggac agtaaagaaa
    37141 aattgagcgt gatgacgacc ttttatccca tgtatgattt tacaaaagca atcgtcgggg
    37201 atgaaggaga agtagagtta ttgattccag cagggactga ttcccacgat tatgaacctt
    37261 ctgctaaaga catggcaaag atccaagata cagatatctt tgtttataat gatgaaaaca
    37321 tggaaacatg ggtccccgca atccaaaaaa cattacaaga aggcaatgtc catacgataa
    37381 aagcgacaga aggtatgctt ttacttccgg gaagtgaaga aggacatgat catgaccatg
    37441 aacacgggga agaaggccat acacacgagc tagacccaca tgtatggcta gcaccaagtt
    37501 tagcaatcaa gcaggtagca agcatacgtg atcagctgat tgaagcttac ccagaaaaac
    37561 aggaagtatg gacaaaaaat gcagcagcct ataccgagaa acttcaagca ctccatcagc
    37621 tttatcaaga aacctttaag caagcaaaac aaagatcttt tatcacgcaa catgctgcat
    37681 tcaactatct ggcattagaa tatggattga atcaagtatc gattgctggt ctttcttcta
    37741 gtgaagaacc gtctgcggcg agaatcgctg aactgaaaca ctttgttaaa gaacatggaa
    37801 tcaactatat ttattttgaa gaaaacgcca aagatagtat tgccagaacg ttagcaaatg
    37861 aagcaggtgt atctttagaa gtattgaatc ctttggaagg attgacgaat gaacaaatag
    37921 aaaatggaga aaactatctt tctatcatgg aagcaaacct cgaagcgttg aaaaaaacga
    37981 cagagacaga aaacccgtta gaagatactt tgacccccaa aaaagaaaag agcgtctata
    38041 acggttattt cgaagacgag gatgtacaag atcgctctct ttcagattgg gcaggaactt
    38101 ggcaaacagt agatacgtat atagaagatg ggacatttga tcctgttttt gaatataaag
    38161 aaaaattgaa tcaggataag acagcacaag aatataaaga atattatacg aagggctatc
    38221 aaacagatat tgcttcaatc aagatcagtg agaaagagat ggcatttacg tttaaggatg
    38281 gaacaacgaa acgttcaaat tatcgttatg tagggaaaga aatcttgacc tacgaggcag
    38341 gaaaccgtgg cgtaaggtat ctattcgaag cagaagataa ggaaagtggc gcttttagat
    38401 atattcaatt cagtgatcac acgattgcac cggctgactc cgaacatttt catttatatg
    38461 caggaaatga aagtcaagaa gcattgctga aagaaatgga gaattggcca acattttatc
    38521 cagatacaat ggatggacgt gaaattgcac aggaaatgct tttgcactga taggcaaaaa
    38581 agaaccgaag ggtttggatc ggctggtcat ttagtcggtc caaactattc ggttcttttt
    38641 atgaaatcaa tttctttaat ccacggatag aggctgggat ggtctcgccg tttgccaacg
    38701 tgacttctct ggttttttta ttaatcgacc gcacattttg tgtattgata acataggatt
    38761 tatgacaacg gataaaattc cgatgcattt tctcgatttc tttgatcttc tcatagaatt
    38821 gtaattgggc atgagtcaaa tggacttcca gtttatgtgg tgctcctagc gaagtagaaa
    38881 aatattggat gtctttgatc ggtaaaaatt tgatctcatc attaaactct attttgaaga
    38941 tatctttttg gatctgggac atttgaaaat cttcgaaaat tttgctcagg atatgctcga
    39001 cattttcttt taaatcataa agatcctctt tgacgatata atcagtcggt tcaatgttgc
    39061 tttttaagat tttcatcgac atttccgtat gggaagtcac atagattatt tttcctaaag
    39121 gatctaattc acggatcaat ttaccgatcg ctacaccatc catttcactg tcttctagtt
    39181 cgatatctaa aaagtaaata ccaaaagaag aagttctgat cttggctgca ttgagaagtt
    39241 cttccggatc agaggtagaa atatggacat aactgtctaa gttttcaatc atgattctat
    39301 ttttgatcac cgttgataaa acttctaatt gttttggatc gtcttcacaa atataaatgg
    39361 gaatcatatc attactcctt tattttattt gtatataaat cgtttgagaa aaacgctggt
    39421 tttcaattga tgtttcaagg aaaagataag gattggtctt tgtcaattca tccaagataa
    39481 acaagccaag gccttcgttt tttggatttg tttttgttga gaaccctttt tgtttcaact
    39541 ggtttaacgg caatgtattt gttgttgtat tgatcacacg aatcattacg gaatgattct
    39601 tcttgagtat ggtcaattcg atttttttct tctttgcagc actagctcct tcaatcgcat
    39661 tgtccaagat aataccaagc atacgtacaa ggtttaccgt atgtttcgta tccagttcga
    39721 ttggctcagg aaaatgaagc tggacgacca accctttttc ctgtgccatc atgagtttta
    39781 atgacagtaa actacggatc tcaggaactt tcatattatc caacatactt agattggccg
    39841 gaaaaaggtt catcatctgg cgtgtaggta atatcgtttg atcataataa gaccgtaatc
    39901 cttctaagtc gccttctgaa atatagctgt gaagagaaaa aagcagattt tggtaatcat
    39961 gtttgaattc tctcaagtct tgatagtttt tttctagatc tttgatataa tcctgttgca
    40021 tcctgacttg ttgctctaat aactgatcag ctaatttctt attagagatt ttccaataat
    40081 aaaccaagat gatcaggcca acacacagat atagaatgaa aaaactcgta ttcaaagcta
    40141 agacatcagg tgtttcacca gaaaaacggg tataaaaaat aatgatatag tatgtaaata
    40201 atatcaatgt cccgatcgta ccgatcatac ggcggtccac agtgtgaaac caagtctcta
    40261 acgttttttt aaaacaaaaa gctaataaag cagataaaaa agcggataag gcaatgtgaa
    40321 aatactgcaa tgaatctcct ggttcaataa ccgaagattt caaaacaaaa aaatcgccga
    40381 tgcttgttaa gtgatctcct aaaagcgacg tcaataaccc aaaaggaagg gcgtaaacca
    40441 attgttgacg cgaagtcgaa aagaagaaaa aagtaagcat cagcattcct atagcaatta
    40501 gagcagtaaa aatccctaaa atcgaataga cccatccaat caaaatacaa gaaatcagaa
    40561 tgactcccgc aaacagatat ttgtatcgga tgtgatggtc aatcaataag atacaaattg
    40621 tgtaaatcaa atattgcaac gctatggacc ataaaaacat aaagtacagc tcccattgat
    40681 ttttaccaaa ttatagcaca attagcgtat tattttttta atttttcagg gattttgaat
    40741 tcagaactca taccaaagca gcagccagat acaaaaaagt cagataagtt agttaattgt
    40801 ttaatgattg tttttttcat gaaagattcc tccaaaattc atcaagtagt ttgtaatagg
    40861 aagcaacgta gctatttcta aaacaatccc aagtagcaaa taggtagaaa agtaagaagc
    40921 tgagaaaaat aaagtaatga gagaaaaaat tagaaacatg ctgatcgcct tctttaataa
    40981 tgggggacgt ttctcgggtt caatgggatt gattgctgta cctcttgatc catagcgaag
    41041 cagtaacaaa aagcagctga ttaacaaaaa gaccatcatt gggaaggaga tagtcaattg
    41101 cagatgtttc atcaccaagg gaacgcccca taaataaagt agtgtccaca gcagacaaac
    41161 gaattcagag tcggaatgca atccataagc atatctgcgg atgcagatat aagaaagaaa
    41221 ggtgattcct gtttccgccc atgagcctgt caccagagaa aagactagaa cgaccgctag
    41281 ttttccaaga ttattcaata aaacttctaa ggcaaatttt acttggacat acaccatatc
    41341 ttcttccgat ttgtctccgc tgaataaggc ttctaataat ttgttcacaa ctttatcttt
    41401 catctcatac gtacctccac cacaaatttt atgctaaaaa aaataaaaaa cgtcttttgt
    41461 ttcataaaaa gtggttttga catcaaaacc gtcatgattt cctaaaaaaa tcttcgtttt
    41521 ccaagaacct taccaaaaaa agtgacagtt ttgatacgaa aagtactttt tatgacaagt
    41581 ttgtgctttt tcgagtgatt tatgttaaaa aattactgac cttataaaag gtgatggagg
    41641 gattcttatg gaaaatgaac aattgtttga agtcggcgaa acatatgcat ttaaatctga
    41701 tttatttgaa tcaccaataa aaggaaaaat agaaaaaatc tatgaaaata gtgtgatgat
    41761 acgtgtcatg aaatgcgcag tagaagacaa tgataccgct cataatctgc actggcagtt
    41821 agttgtacgc aaatcaagta caatagaaga ataaaaacag ataaaatgtt gagagcataa
    41881 agaggttgtg agtctcccgt ttagctctga gttacaagga ataatgttaa aaaacagctt
    41941 ttcatgtttt atgaatattg ccttgtgacc gaggtgttgg caggagaata ctgtttattt
    42001 gaaaaaaggg ctgcgacaag acttttgtca cagcctttat tttcatgaat aggagttact
    42061 tttggctact tttagagaag tagcatttaa ggagcagata aagtcaaggc ttttatttct
    42121 ataaatgaag tagtaaaatg aagaacagat tttattacag gaaggatgcc gataattgtg
    42181 atcattgttg caggaacgat cggtgcaggg aaaagcacac tgactgaaat gcttgcccaa
    42241 gatttagaaa caaaaccttt ttatgagaac gtggaagata atgaagtatt gccgctattt
    42301 tattctaatc cagaaaagta tactttttta ttacagattt tctttttgaa caaacgcttt
    42361 ttggcaatca aagatgcttt cagccatgat gacaacgtac tagaccgctc catctacgaa
    42421 gatagtatgc tgtttcattt gaatgcagat ttagggcgtg tttctgaagt agaagtaaag
    42481 cagtatgaag gtcttttaga aacgatgctg aaggagttag aagaaatttc gccacaaaag
    42541 aaaccagatc tactggttta tattcgtgta tcctttgaaa ctatgttagc gagaatcaaa
    42601 aaaagaggcc gggaatatga acagctagaa caagatcctg aactctattc ctactataaa
    42661 gaactcaatc gacgatacga agagtggtat gaacagtttg atatatgtcc caaaatagtg
    42721 atcgatgggg acaaatatga tttcgtagcc gatccggcat gtggagaaca aatcgtacaa
    42781 gaaatcaaga tgcgggcaaa gaaaatgaca gaagaggcag atgcccagtc gatccgctac
    42841 actacaaata acccgaaagc aaagggaatc tttacaacta aataatataa aaactaagca
    42901 aattgctcac tcgcagatat ttctctgtga gcagcatctt gcttagtttt tttgattcat
    42961 tgagatcaaa tagtgaaccg attcgtatga taaaattgcc ataaatgaaa tgtctgagtg
    43021 agggccatga tcaaaaataa aatggaaacg atcaaaatcg aatgggcgcc aaacagatga
    43081 tgacagaaaa caaggacaat agctcctgcg ataaaggcaa gaacgacact tagatagtgg
    43141 aaaaatcgat caaaatctgc tttttcttta gaaatacaat aatcatataa gttcgttgct
    43201 acccctttta aatttccagt tgtaaataaa ttagtgtagg cacgcccgtt gattttatca
    43261 aaagctaccc actggatcga tgcagtaaaa gcaatcaaaa tcgttactaa tgcgggatgc
    43321 tcatggacgg gtgtcaaact aacaaagaaa aaaatcactg cttcataata tagaacaaac
    43381 aagcgccaga aatgtttttc tttttttcta aaataatcaa tcagatactt tgttagaaga
    43441 atccctaaga aaaagaaaag ggtagacaat acttttttac caacacttag ccattctccg
    43501 tcaaatgctt ggatgatcga tagaatgata ttgccagttt gagcagaggc aaaagcacca
    43561 tattggatat aagtataact gtccatggct cctccgataa atgtcagcaa aagtcctatt
    43621 gtacgcccct cgtgaaagga agtctgcatt tttttcatca ccttttatga atatttttgt
    43681 cttccttatc ttagcataaa cgattgaaaa aaaggaaaaa ttttcagaaa actaaaatca
    43741 tatcgcttcc cattttcatt tttagaaagg tctgttagta taaagaaaaa atagacaaca
    43801 aaactttaaa taaccaactt taaataacca actttaaata accaacttga aataaacaaa
    43861 ttcaaagaag aaagatggga aggaaatcaa tcagttgaat gaaaaagaaa ttctccgatt
    43921 acaaaaagaa ttgaaacgct gggagaacaa gtataaaaag cttcaacaag tctttcggct
    43981 acaagaagaa atcattgcta cctatgaagc ggcttatggc gaagcacccg gacttattga
    44041 ggaagaagta caagtaaaag aaagtgaagg aaacagctct ttctttaaaa tgatggagaa
    44101 acgttcctat aatcgcttca atcaagaaca aaaagcagct atcacatatg atatgaagaa
    44161 acatcttcga atcatagcag gagctgggag cggcaaaacg caaacaatct gtgcaaaagc
    44221 tgtttatctg atgacgcaaa aacaagtaga cgaagaacgc atactaatga tcacttttac
    44281 aaggaacgct gcaaatgaac taaaaaaacg agtagataat ttcagccaga gaaaaaccgc
    44341 tgtccatatc ggaacattcc atagtatctt ttttaggata tacaatgaaa tttgtcgaaa
    44401 atttcctgaa gtagcaatgc aaggaataca aggagacttt tcaaaggata ctgcacaaaa
    44461 agtgaatgct gttttgcaac agctgatacg taaatataat ctttatatat ttgatcaata
    44521 tggagaaaaa acgattgctt ctcggttaga ctattggcag aatatgaacc tttcagtaga
    44581 agaaatggtt cagttagtta aagaaaaata tgattccatt gataagaatg cacgacagcc
    44641 gatatcagaa cgactgtatg gattgctcac ggaactccaa gaacaaaaaa gaagccagca
    44701 attgctagag ttcaatgatg tactccaaaa tctgaaaagc gctttggaga atgaggagat
    44761 ccagcattat atcggccaaa aatatgatta tctattcatt gatgaatttc aagatactaa
    44821 tccacttcaa tgggaaatcg tgaaacggat gacaaaggaa aacaggatca agttgattgt
    44881 tgttggagat gatgatcaga gtatctatgg attcagagga tcagagccag catacatcaa
    44941 gaactttgaa aaagaatatc ctaccaaaac tcttttctta ttaactaatt atcgttctcg
    45001 ggcagctatt gtccaaggag caaatagatt gatcagctat aataaaaatg atcggatacc
    45061 aaaggcgatg attccagcac aaaaagaagc aggtgttatg gaagcctatt tgttttctga
    45121 tactaaagca gaaagtcagt ggctaatcaa acaaattcag acatttattc aaaaaaatgg
    45181 gaaatataag gaatcaatca tattataccg atcagcttca caaacgcagc agcttgtcca
    45241 atctctgctg aaaacgaata ttccttttgt actggaagca gatagtccat atgaaggtat
    45301 ctttggtatc aagtctttcc aacatttcta tcaaaaaatt gttcattggc aaacagcact
    45361 gaatctgcaa aagaaaaatc aggcctacca gcaattgctc cggcagctga tggcagactg
    45421 ctacctgaaa aaaagtgaat gcgatcaata cttttctcct aaatatcaaa atatagccgt
    45481 tgcagattat attttgtcga taagccccaa tttaaaatcg aaatctgcag aaatccgaga
    45541 gtttgaggaa gcgttgcgta aaacagacca gcatcaagaa atctattcgc ttgttcaaag
    45601 ctatcttcat ctgccacgta tagctaagga aatcgaccag agtgatcaag aatggatacg
    45661 agaagaagta aagcagcatg ctactttcag aagactccaa gccttatcgc aagaaaccca
    45721 agcgacagct aaagaattaa aaacccgctt gattgcttac agacaaggaa aacttgatgc
    45781 actatgtatc cagagcattc acaaaagtaa aggtcttagt taccgaaatg tctttttgat
    45841 tggttgtaac gaaggaagtt tgccttataa cggagcgaca gaaaagaaag taatcgactt
    45901 taatgaaata aaagcagaac cagtgacgac gatagaagaa gaacgaagac tattttatgt
    45961 tgcgatgact agagcaagaa atcgtctgta tctatgtgta cctcaaatga aaaattcaag
    46021 aaaattgaaa gtatcgagat ttatcaaaga aaccgggagt cgtgtgaaaa aaggaaagtg
    46081 atagaagaga gggtgtgaca gaagtggtca gtttcaagaa agaagaagga atgtacgaaa
    46141 attgcttctc aaatttttgt gaaacttcag cttattttcg aagaagctat ttctggaaca
    46201 cagtttattc ggaaa
//
LOCUS       DAXLPQ010000019        40522 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.019, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000019 DAXLPQ010000000
VERSION     DAXLPQ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.019"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(513..2009)
                     /gene="lysS"
                     /locus_tag="ACF3UO_001258"
     CDS             complement(513..2009)
                     /gene="lysS"
                     /locus_tag="ACF3UO_001258"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFD3657299.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2120..3124)
                     /gene="dusB"
                     /locus_tag="ACF3UO_001259"
     CDS             complement(2120..3124)
                     /gene="dusB"
                     /locus_tag="ACF3UO_001259"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFD3657300.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3125..4012)
                     /gene="hslO"
                     /locus_tag="ACF3UO_001260"
     CDS             complement(3125..4012)
                     /gene="hslO"
                     /locus_tag="ACF3UO_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFD3657301.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4229..6340)
                     /gene="ftsH"
                     /locus_tag="ACF3UO_001261"
     CDS             complement(4229..6340)
                     /gene="ftsH"
                     /locus_tag="ACF3UO_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFD3657302.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6430..6975)
                     /gene="hpt"
                     /locus_tag="ACF3UO_001262"
     CDS             complement(6430..6975)
                     /gene="hpt"
                     /locus_tag="ACF3UO_001262"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFD3657303.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6975..8420)
                     /gene="tilS"
                     /locus_tag="ACF3UO_001263"
     CDS             complement(6975..8420)
                     /gene="tilS"
                     /locus_tag="ACF3UO_001263"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFD3657304.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8540..9010)
                     /locus_tag="ACF3UO_001264"
     CDS             complement(8540..9010)
                     /locus_tag="ACF3UO_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFD3657305.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9056..9481)
                     /locus_tag="ACF3UO_001265"
     CDS             complement(9056..9481)
                     /locus_tag="ACF3UO_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFD3657306.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9548..9817)
                     /locus_tag="ACF3UO_001266"
     CDS             complement(9548..9817)
                     /locus_tag="ACF3UO_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFD3657307.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9828..11423)
                     /locus_tag="ACF3UO_001267"
     CDS             complement(9828..11423)
                     /locus_tag="ACF3UO_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3657308.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11438..14959)
                     /gene="mfd"
                     /locus_tag="ACF3UO_001268"
     CDS             complement(11438..14959)
                     /gene="mfd"
                     /locus_tag="ACF3UO_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFD3657309.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVSDQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14976..15536)
                     /gene="pth"
                     /locus_tag="ACF3UO_001269"
     CDS             complement(14976..15536)
                     /gene="pth"
                     /locus_tag="ACF3UO_001269"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFD3657310.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15889..16863
                     /locus_tag="ACF3UO_001270"
     CDS             15889..16863
                     /locus_tag="ACF3UO_001270"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD3657311.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17033..18433
                     /locus_tag="ACF3UO_001271"
     CDS             17033..18433
                     /locus_tag="ACF3UO_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFD3657312.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18511..19233)
                     /locus_tag="ACF3UO_001272"
     CDS             complement(18511..19233)
                     /locus_tag="ACF3UO_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657313.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19312..19818)
                     /locus_tag="ACF3UO_001273"
     CDS             complement(19312..19818)
                     /locus_tag="ACF3UO_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3657314.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19941..21740
                     /locus_tag="ACF3UO_001274"
     CDS             19941..21740
                     /locus_tag="ACF3UO_001274"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFD3657315.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21808..23382)
                     /locus_tag="ACF3UO_001275"
     CDS             complement(21808..23382)
                     /locus_tag="ACF3UO_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFD3657316.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23637..24146)
                     /gene="mreD"
                     /locus_tag="ACF3UO_001276"
     CDS             complement(23637..24146)
                     /gene="mreD"
                     /locus_tag="ACF3UO_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFD3657317.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24150..25004)
                     /gene="mreC"
                     /locus_tag="ACF3UO_001277"
     CDS             complement(24150..25004)
                     /gene="mreC"
                     /locus_tag="ACF3UO_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFD3657318.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25159..25797)
                     /locus_tag="ACF3UO_001278"
     CDS             complement(25159..25797)
                     /locus_tag="ACF3UO_001278"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFD3657319.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25798..26448)
                     /gene="rpe"
                     /locus_tag="ACF3UO_001279"
     CDS             complement(25798..26448)
                     /gene="rpe"
                     /locus_tag="ACF3UO_001279"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFD3657320.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26461..27360)
                     /gene="rsgA"
                     /locus_tag="ACF3UO_001280"
     CDS             complement(26461..27360)
                     /gene="rsgA"
                     /locus_tag="ACF3UO_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFD3657321.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27525..29594)
                     /gene="pknB"
                     /locus_tag="ACF3UO_001281"
     CDS             complement(27525..29594)
                     /gene="pknB"
                     /locus_tag="ACF3UO_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFD3657322.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29591..30331)
                     /locus_tag="ACF3UO_001282"
     CDS             complement(29591..30331)
                     /locus_tag="ACF3UO_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFD3657323.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30344..31702)
                     /gene="rsmB"
                     /locus_tag="ACF3UO_001283"
     CDS             complement(30344..31702)
                     /gene="rsmB"
                     /locus_tag="ACF3UO_001283"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFD3657324.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31702..32640)
                     /gene="fmt"
                     /locus_tag="ACF3UO_001284"
     CDS             complement(31702..32640)
                     /gene="fmt"
                     /locus_tag="ACF3UO_001284"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFD3657325.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32633..33124)
                     /gene="def"
                     /locus_tag="ACF3UO_001285"
     CDS             complement(32633..33124)
                     /gene="def"
                     /locus_tag="ACF3UO_001285"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD3657326.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33139..35547)
                     /gene="priA"
                     /locus_tag="ACF3UO_001286"
     CDS             complement(33139..35547)
                     /gene="priA"
                     /locus_tag="ACF3UO_001286"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFD3657327.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35800..36105)
                     /gene="rpoZ"
                     /locus_tag="ACF3UO_001287"
     CDS             complement(35800..36105)
                     /gene="rpoZ"
                     /locus_tag="ACF3UO_001287"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3657328.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36110..36724)
                     /gene="gmk"
                     /locus_tag="ACF3UO_001288"
     CDS             complement(36110..36724)
                     /gene="gmk"
                     /locus_tag="ACF3UO_001288"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFD3657329.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37211..37495)
                     /locus_tag="ACF3UO_001289"
     CDS             complement(37211..37495)
                     /locus_tag="ACF3UO_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657330.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37513..38403)
                     /locus_tag="ACF3UO_001290"
     CDS             complement(37513..38403)
                     /locus_tag="ACF3UO_001290"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFD3657331.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38423..38641)
                     /locus_tag="ACF3UO_001291"
     CDS             complement(38423..38641)
                     /locus_tag="ACF3UO_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFD3657332.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38611..40311)
                     /locus_tag="ACF3UO_001292"
     CDS             complement(38611..40311)
                     /locus_tag="ACF3UO_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFD3657333.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
BASE COUNT        10970 a         8791 c         7331 g        13430 t
ORIGIN      
        1 tttttggctg ccgtagcaac ttttatatca tatcagagag acaagcgatt gtcaactctt
       61 ttttaaaagt ttttttcgat ttcgtttttc gaaatctttc ggcaactcat ttaccataac
      121 ttatcgtttg ttatttgtca agaacttttt tgaagttttt ttcgatagaa tcaagcttcg
      181 caagtggttc ttttttaacg actcagttat cttatcatgt cgttagtaac atgtcaataa
      241 cttttttgtt atgtttttga ataaatattt tcttctgtct tttggacaag taataatata
      301 ccaactaaat ttagcttggt caacgaattt tttgtatttt ttcaagtttt tttcaataaa
      361 cgattattca taacttttct ttctttatcg ttcgttttcg tcttctttaa tgtctagaat
      421 agtcggcatt agcttttgaa ctttcgttat tatttattcc tttctacaca gcaaaagctg
      481 cctaaggaat tccttagaca gcttttattc gattatctca ttgttgggaa tagcaaaaca
      541 tcccgaattg attgtgcatc agttagcaac attactaatc tgtcgatccc gatgcctaga
      601 ccaccagttg gcggcatacc gtattctaag gcttccaaga agtcttcgtc tacaccgtga
      661 gcttcgtcat ttcctagttc acgttctttt tcttgcgctt cgaatctttc tctttgatca
      721 attggatcgt tcagttctgt aaaggcatta gcaaattcgc gccccactat gaatagttcg
      781 aatcgatctg tgaatcgagg atcttctgga tttttcttcg ctaaaggcga aacttcgact
      841 ggatgtccgt atacaaacgt cggttgtgtc aatgtttctt caacaaatgt ttcaaagaat
      901 tcattgataa catgtccgac acccatagct tcggttactt ctacattgtg tttttcggct
      961 aaagctaatg cttcttccaa tgtcatttct tgccagaagt ctacaccagt ttgttctttg
     1021 attgcatcta ccatatggat gcgtttaaag tcactttcta agtcgacagc ttgtccatca
     1081 tatgtgattt ttgctgttcc tagtactttt tcagctgcgt tacggataat accttctgtc
     1141 agattcatta catcattgaa atcagtatat gctgtgtatg cttctaacat cgtaaattct
     1201 ggattatgtg tagtatcaat tccttcatta cggaaaacgc ggccgatttc ataaactttt
     1261 tccattccgc caacaattag tcgttttaaa tgaagttcta gcgcaatacg caaatataaa
     1321 tcaatgtcca gtgcattatg atgcgtgata aatgggcgtg cggcagctcc acctgcctca
     1381 ttgtgcaata ctggtgtttc tacttcaata tagccattgc catctaaata gcgacggatt
     1441 tcgctgataa tttggcttcg tttcataaat cggtcaaagc tttcgcgatt actgattaaa
     1501 tccaagtagc gttgtctgta gcgttgttca atattcgtta agccatggta tttatctggc
     1561 agtggacgaa gtgcttttga caaaatcgtg atttctgaag ctttgataga aacttcgcct
     1621 gtgtctgttt tcatgatttg tccagttaca ccaaagaaat ctccaaggtc tgcatgtttg
     1681 aatacttcat aggcctcatc acctacttgg tcttttctta cataaatttg aatttggcct
     1741 tcacgatctt gtagatgcgc aaatccagct ttcccttttc ctcggcgagt catcatacga
     1801 ccagctacac tagcggtcaa tcccatttct gctagttctt cttttgttct tggatcaaat
     1861 agttcatgca attcttctga gttgtgcgtg cgttcaaatc gttttccaaa tggatcgatt
     1921 ccatcttcac gcaattgttc cattttttga cgacgtacaa gcatttgatc atttaaatct
     1981 tctacttgat gttgttgttc ctgtgtcaca aaagttcctc cattctcatg ttaatctctt
     2041 tcctataatg ccaatgaaac acaaaaaaag caagccgaac ttggaatttc ggcttgaaaa
     2101 ttcacgaaaa acttagaaat cacaacgttt gtttcaatag tactttttcc gctttttcta
     2161 caaattgatc cagcaggtca ttgatttctt gctgtttttc tgtctgattg attgctactt
     2221 tcactttcgc tgctcgagga atccctttta aataataagc cgcatgtgtt ctgaattctc
     2281 tacaagctac tttttctcct ttgagatctg ctaagcgttg taaatgaagt ttagctgtag
     2341 caattttttc ggctggtgtt ggttcaggaa tcagttcccc tgtttcgaga taatgctgtg
     2401 tgcggtgaat catccatgga ttgcccagcg ctgcacgacc aatcatcaca ccgtctgcac
     2461 cgacatagtc aagcatccat tttgcatctt ctggcgtttt gacatccccg ttccccataa
     2521 atggaatcgt caaatgtttt ttcacttctt tcaatacttc ccagtccgct tttccttcat
     2581 acatctgaac ccgtgtacgt ccatgcatag cgatggcact tgctccagct gattgtgctg
     2641 ctaatgcatt ttctacagca aagacgtgct cttcatccca accaatacgc atcttgattg
     2701 ttactgggat atttactgct gaagaaacag cttggaccat ttcgtatact ttctcaggat
     2761 ctaaaagcca ttttgctcct gcttctgctt tgattacttt atttactgga cagcccatat
     2821 tgatatctat tatatcggca gctgtgtttt cttcgacaaa ttgagcagct tcaactagac
     2881 tatctttatt tccgccaaat atctgtaaac ttaatggatg ttctgtttct tcaatgtgga
     2941 gcatctctaa agtttttttg tttctgaaat gaataccttg gtcactgatc atttcacata
     3001 cgactaagcc cgcaccaaat tctttgacag tgactcgaaa tgctgaattt gttattccag
     3061 ccatcggtgc aacaacgaca cgattaggga tttccacatt gccaattttc catgtgtgtt
     3121 ccacttaaat ccctcctaag gcttctttct tcaatccatc taattcttct tcgctatact
     3181 tgtatttgtt attacagaaa gaacaaaccg cttctgcacc gtgatcttcg tctatcattg
     3241 cttggatttc ttctgcacct aacgcgataa ttgcttctgc aaatttttct tttgaacagt
     3301 cacatttgaa ttgaacaggc attttttcca aaatgttcaa ttcttctgta ccaagcaatc
     3361 ctttcaatat ttcttctggt gtctgtcctt catctaagag ggtagagatt cttggtgtcg
     3421 tttttaattg ttcttcgatc ttgctgattg tttcttcatc ggcacctggc atgatttgga
     3481 tcatgaatcc tcccgccgtc ttgatgctgt cgtcagtatt gaccaataca ctcagtccaa
     3541 cagctgaagg gatttgttct gagatagcaa gatagtaagt aaaatcttca gcgatttctc
     3601 cagaaacaat cggcgtttgc ccagaaaaag gttcttttaa tcctaagtct tttgtgacag
     3661 taaacattcc ttgtgttcca actgctcccc gcacatcgat tttaccttca ctatttagag
     3721 gaagactgag atgcggattt ttgatgtaac ctttcacatc tccctttcca tttgcatcta
     3781 ctacaattcc tgttgctgga ccatcgcctt ggattcgaac agttagtttg tcttctcctt
     3841 tgagcgtcgc accaagtagc agactaccga ccaatgtccg tcccaaagca gctgaggagg
     3901 tgtgccaagt atcatgacgt ctttgtgcct ccgctacggt atttgttgct tgaacggcgt
     3961 atgctcggac gaatccgtcg tgagcaagtg ccttaaccaa ataatctttc atttgttatg
     4021 tactcctttt tccgttttta aactcatagt gaatcatact agcaactact gcttttttca
     4081 actttggaat gcttctttta aaaataattc agaatcatct agaaaacagg acatcaccct
     4141 atttacaact taaataaaga aatctcccga aaaccggttt ttgttccggt tttcgggagt
     4201 catatcagat caattgacct atattttttt atttgtattg atcgtctgaa tgattatctt
     4261 ctgattgttg agaatctgaa tcatgttctg ctttattttc ctcattcagt tcatgttttg
     4321 cttcttcaaa atcacgtttt tcttccgctt gtttttcagc gtctttttct tccaaagcac
     4381 gttttgcttc ttcaaaagtt ttcgcttctt tttcgcttgg ataatcattt gactcagtac
     4441 cttcaggcat cacaccgtgt tcaaacaatg acttgattgc tttggcatcc aatgtttcga
     4501 attccaaaag tttttcagca atcagtttat gctgtgcacg atgagcttcg atgatttctc
     4561 gagctttatc atgagcttcc atcaagattt ttcgtacttc ttgatcaatc tcgaaagcga
     4621 cttgttccga gtaagctttt gtttgaccat agtcgcggcc aacaaacact tgatggtttc
     4681 cttcatattg aacaggacct aaacgatcac tcattccata ttctgttacc atgcttcgtg
     4741 ctagagctgt cgcttgctca aagtcattgg aagcaccagt tgattggaca ttgaagatga
     4801 tttcttcagc tgtacgtcca ccaagtaagc ctacgatttg ttcaaacata tcttctttcg
     4861 tcatcaagaa ctgatcttct tttggtaaag cgatcatata tccgccggcg cgtccgcgag
     4921 ggatgatcgt tactttgtgg acgacccgag cgcgactcaa tactaatccg acaatcgtat
     4981 gaccagcttc gtgataagca accatttcgc gttctttttt gctgattacg cgatcttttt
     5041 tagctggacc tgcaatcacg cgatcttccg cttcatcgat atcagaagca tcgattttct
     5101 ttttatttct tctagcagct actaacgctg cttcattcaa gacattttct aaatctgctc
     5161 cggcaaaacc tggtgtctgt tgagccacaa ctttcaagtc aacgtcatct gccatcggtt
     5221 tattccgtgc atggactcgc aagattgctt cacgaccttt tacatctgga cgtccaacta
     5281 aaatctggcg gtcaaaacgg cctggacgta gtaacgctgg gtctagtaca tcagaacggt
     5341 tggttgcagc aatgacgatt actccttcat ttccgtcgaa gccatccatt tctacaagca
     5401 attggttcaa tgtttgttcg cgttcatcat gtccgccgcc cataccggca ccacgttgac
     5461 gacctaccgc atcaatttca tcaatgaaaa tgatagctgg tgcgtttttc ttcgctgttt
     5521 caaacaaatc acgaacacga cttgctccaa caccgacaaa catttctacg aaatcagaac
     5581 ccgagatcga gtaaaacggt actccagctt ctccggcaac agcttttgct aataaggttt
     5641 tacctgttcc tggaggtcct tctaaaagta cacctgccgg gatacgggca cctaattcaa
     5701 caaatcggcg aggatctttc agaaattcaa caacttcaac tagttcttgt ttttcttctt
     5761 ccgcacccgc tacatcagaa aaacgtacgc gattagcttt tttgtctgct tctttggctt
     5821 ttgatttacc aaagttcatg acacggccgc caccgccacc gccgccgcct tgttgtccca
     5881 tcatcatgta aaagaaaaag atgatgatta cgattggcaa gaagctaagc aatagggaaa
     5941 cccatatacc gctgcttgat tcttctttta ctgttgtagc aactttgttt tcttttgcca
     6001 gttctgttac ttggctcaat gttgtatcat ttggcaaaat gattgttgtg aaatgggtag
     6061 tagtcgtatc tgttgaacct aagatagcta acccaccgct gttagcgacg gtctgctgtt
     6121 ctttgtattc accagtgatc ttatatacac catttgcagg ctgcacttca aattctttga
     6181 tcttgcctgc ttgtagttgt tctgtgaatt ttgagtactc gatatctgac gatcgctggc
     6241 cgttattacc aaaaatgaaa taaacgacca ttaccatcgc taagattacg aggacataat
     6301 acaaggcatt tttcatcatg ccgttgttct ttttgttcat agttgccctc cctaagcgtc
     6361 aatttaattt aacagttttt tatcaatcct gaccattcta ttgtaccata atttaattga
     6421 gatacagcat taatttgatt gataaacact aggtttcaat acaccgatgt acggaaggtt
     6481 acgatatgct tctgcataat ccaagccata accgaccaca aattcatttg gtacgttgaa
     6541 gccaacataa tctgcttcga tatttactac tcttccttca ggtttgtcaa gtagtgtaac
     6601 aattttgact gattttgctt tgcggtattt gaaaagatcc actaaataag caagtgttct
     6661 tccgctgtca atgatatctt caacgatcaa cagatcgcga ccttctacat tcgtatctaa
     6721 gtctttgacg atttttactt cccctgacga gactgttgca ttcccgtagc ttgaaacatc
     6781 catgaaatcc aattccaaat acgtatcgat agaacgaacg atatctgcca tgaatggtac
     6841 cgctcctttt aagacaccta ctactagggg attggtgttt tggtaaattt ctgttaactc
     6901 tttgcctagt tctttgcaac gaacttgtat ctcttcttgt gagatcaaaa ttctctcaat
     6961 atccttttcc aacatcaggt tctccttcca attgcttctt tttgatattt gtaaagaagt
     7021 atgtagtgta ttttatcagt ttcttcacga atactcaaat atgaaaaggc aaaaggtatc
     7081 aagctatata tatttctttt ggcatctgta atgatccaag catgctgcct ttgtgaatta
     7141 ggtactttct gatcgataaa atatctagat actttttttg tgagattctc tgttaattta
     7201 atgcggtctc ctgcttttct tttttcgaca tacagttgca catcagcagg aatccaaatg
     7261 tcatgagaaa atagagacca tgaatctgtt gctttgatgt cccctgcatt ttcaggtttg
     7321 accagaccaa tccattctgt ttcattcaaa tatattcctt gttctggaat cagcaacaag
     7381 cgctggtctt ctgtctggct agttgcttgt ttttcttttt tagagagtac aacaaaatga
     7441 tactctcttt tcagtatcca attattgcca atactgagtt gccattggct ttttttctgt
     7501 tgccactggt ctaaaatcga ctccatttgt tgttctttca aaataattcc tgtttttgag
     7561 aatgctttgt cgaaaaagga gtaaaaaaaa tagtatcgtt cagcatctgt catttcttca
     7621 atcatttctg cagaaaatcg aaattgttcc tcccactgtt cgacttcctt ttcgatcaac
     7681 tgtcccatat atttttgaat gacttggtct gcccattgga tctgttgcga aaattgctgg
     7741 aaatgtctca acgcctgtgt attttcttgt ttcaattgag gaactaccaa atgacgaagc
     7801 cgatttctct ggatatctaa caattggttt gtctgatcct caaagtaaac aagctgcgat
     7861 tccgctgcat aagtatatag gtcttctttg ctaaaactca gcaacggacg aatcagtctg
     7921 cccgtagcaa atggttgtac ttctttgatt ccagaaaaag tatttaactg tcccccacga
     7981 acgattttca ttaacaccgt ctcgatttga tcatctccgt gatgagcagt catcaacgtg
     8041 tcatattgtc cttcttccat cacgcgagtg aattcttgat aacgaaagtt acgagcttct
     8101 gtttctatgg cggatttggc tggatcttcc caaatactta catataaagg gagattcttc
     8161 tcttcacaat atgagcgaag ataggcagct tcttctgctg attcttctct taattggtga
     8221 ttgatgtgga cgatacctaa agaaaaaccg atttggcgtt gcacttgtaa aagtaaatgg
     8281 agcaaaacca tcgaatcaac accacctgat accgctgcta aaattctcga tccttgttgc
     8341 cagaatcctt gttcattccc gtgccgaata aatgactgct gtaatagcgg tgcttttttc
     8401 ccgccttttt caacgttcat cctttccaca ccctttcttc ctaaaaaaaa gagagcggga
     8461 aaacgtctaa aacgacaatt aacctgccct ctgttgatac tatgacccaa atagtcgcac
     8521 tatcattatt tgcggctttt tagctgcgac gtccgccacg gccaccgcgc tttccttctg
     8581 tgtttcgctt caatgaagat aagcggtcat cgctatcttt caaaaatgaa ctcatcaatg
     8641 aatcgaagtc ttctttttga gctgaaggtt gactgcgaga aaaagatttt ttctgtgctg
     8701 gacgatttcg gttgtcacgg ggatcttttt gttgatattt tttaggacgg ctttcttctc
     8761 cagattcagc aggttgttcc tgcgctttcc ggatagatag tccgattttt ccatcatcat
     8821 ttactgaaat aactttaact gttacttcat ctcctacact taaaacatca tggatgtctt
     8881 ttacatagcc atttgacact tcgctaatat gaactagacc cgtttttcca gcacctagat
     8941 caataaacgc accaaaattt gtgattcctg atacttttcc ttgcagtttt gctcctacct
     9001 cgattgacat aaaaaaaatg ttcctcctaa ttatttccct tttttatatt cctgcttatt
     9061 ttgcagttgt agaactagtt gattgatctg tttcatttgt cgagctgtct gtatttgatt
     9121 ctaatatagg ataaactttt tcaccgtctt ttgagtaaaa gaatttgctt ctggcaagtt
     9181 tagctacata ctcatcatct ttcagcaatg aaacatcttg gtgcagctga tcaacgtctg
     9241 cgttgacttc tttcatttca gtatttgctt cgactctcaa ttcgttcaat tgatgcatcc
     9301 tttgcatgtc atggaaaatc tgcacaccta ttatcgcgaa aatgaccaaa gcaccaacaa
     9361 aaattgcagc cagtctgcgt cttcgaaaaa tcagttgacg ttgttgttgc tgaaattcag
     9421 catacttttt ctttgcatat tccgtatcta gcgcagcgat tttattgctt tttttcgtca
     9481 cttggattcg ctccaatctt tttgattgtc tttttcatta taccaatatc gtgaaagctt
     9541 gtctaatcta tttctctagt gtttctgtgc gattttcaga aataatttcg tacatttttt
     9601 gtgcatcttc ttttttggtt gattcatgta attccgtaat tttcacttcc aacgttttgt
     9661 tgccaaactg gactttcaaa atatcgccta ctttgacatc actggaagat ttcgccaatt
     9721 taccgttgat ttgaattctt cctttatcag ctacttcttt tgctactgat cgtcttttga
     9781 tgattcggga aatttttaaa aatttatcta atcgcatatc ttattcctca ctttttaatt
     9841 tttttattta atcgcaggat tttcttacca aaaggcaaca ttagccattc tcgtactgta
     9901 aacagacgaa gacgaatcac tgcataaatg aacacagaag ccccgatccc aactcctatc
     9961 acgctgacaa aaaaagcagt ggaacgatga gttacaggac caaatactat attcaataca
    10021 ccataataca gcagcagtac tactgtcata caaagaaggc tgaacatcaa cttccgtcca
    10081 aaatgccgtt ctttccaaaa agcatttagc tcttttgttt caattcgaac aaaataccaa
    10141 agcgtcacac ctaatcctaa aagggtagac aggcttgcac ctgctgttcc taataaaccg
    10201 gtcagaaaag aagtagtcaa tccttttacc aatagtcccc atcctgcgcc ttttaaagaa
    10261 gggcgaaacg agttcttgct ttgagcaata ctttgataag cttggatgac tgcagtgaaa
    10321 gcaatggaaa aaacaaataa tacaagcgct gcatttcccg cataatcttt aaacaacgca
    10381 taattgatat aagggagcag caaggctaat cccaaagacg cagctaatgc taaagcggtc
    10441 gtcaatctaa gatagatttt ggctgtctgt aaaaactgac gatagatccg gttggtcaaa
    10501 tgacgagtca acgcaggcag gaatgtcgca cttaatgcag tggcaatcac taaacctaat
    10561 tgtactaaag gctgacctcg atcatagacc ccttttgcta tcttcgcacc gtattctgac
    10621 agtccgtaaa cttccaaagc attttttaca aagaaagagt cgatcagctg gaaaaagata
    10681 agcaatccac tataaatcga aaccagtccg ccttctacca gaaaacgccg gatcaagggc
    10741 tttgacggct gtttgaacaa tggaaaccgt cggaagctta acgctcctcc atgaatcttt
    10801 tgttcatagt agtgaaggat cccatatgcg cataaaccgc caaaaacagc tccactcatt
    10861 gctgccgtcc ctgtttggta caccgtccat ccaagctttc taaaagcaaa cgcactacag
    10921 acaatcacaa aaacacgaac gaactgctca actacttgag aaacagcagt tggttccatc
    10981 aagaatcttc cttggaaatt ccctcgataa aaagatagac caggcatcag caaaaaggta
    11041 aaggaaacta cttggatcag cggtttcaat tgtatgtctc ccatcatcca agcaatccag
    11101 ctgctaaatg caaagacaaa caaccacaaa aagacacctg tccaaaatac taagggataa
    11161 agattttgca aagcttgctt tcgctcgaaa ggattctttc tttctgcaac gtactttgat
    11221 atgaactgcg gaagaccgga taaagctaaa gtcattgcta tcccataaat tggataaact
    11281 tgctgataaa cataaaaacc ttcgtcgccg actaagtttt ggaggggaat tcggtaaagg
    11341 gcacttaata cttttgctat gaaagaagca atcgtcaata caaatgctcc ttgcatgacg
    11401 cgccgcattt ctttatgatc caaatcattg ctccttccta cgctgacaga tatttttgct
    11461 cacgcaacgc tttgacaaac ttttggattt cctgaagcca tactgcttct tccatttggt
    11521 tggggatcgt caagcgtatc accatctgtt ctttttcaac gcctagactg gcttttagtt
    11581 ttgtcgctgt cagtgcttcg aataactgtt ccacactata gcgttttgtt ccaactttac
    11641 ttagagtaaa gactatatgc gcctcctgtt tccttatcgt ttctaggagc gctcgatcgc
    11701 catccatttt gatctgccca attgtcaaga gatgtgctac ttcttctgga tattctccaa
    11761 aacggtcgag cagatcatct tctagttcat ctagcatttc ttgcgaatca agttcacgaa
    11821 ttcgtttata gatctcgatt ttctgccgtt gatctgacac gtatgtttca ggtagatacg
    11881 catcgacacc gaggtcgatc tcaacagtgg tcttctccac ttgactattc tttccttgtt
    11941 tacgagaaac agcttcgctt agcatttgag aatacatatc gaaaccgact gcatcaataa
    12001 atccatgctg ctgagcacct aagagattac ctgcaccgcg aatggaaaga tcccgcatcg
    12061 caatcttgaa tccagatccc agttctgtaa aatctttgat tgcctgaaga cgtttttcac
    12121 tgacttcgtt aaggatcttc tgctgctcat acataaagta agcatatgcg acacggctgc
    12181 ttcttcctac ccgccctcgc aattggtata acgtggataa tcccatataa tcagcgttct
    12241 caacgaacaa cgtatttgcg ttcgggatat ctactcctgt ttcaatgatg gttgtagtga
    12301 caagaacatc atattgacct tcaataaatt caaaaagcgt attttctaat tgcgcctctg
    12361 tcatttgccc atgagcataa ccgatccgtg cttccggaac gagttcttgg atttcttcta
    12421 ctttttgttc gatcgtttct acccgattat ataaatagaa tacttgtcca cctcgtccca
    12481 tttctcgatg gattgcttcg cgaatagccc caggattttt ttccataaca tacgtttgga
    12541 tcggataacg attcgcaggc ggtgtttcga ttactgaaag atcccgcacg cctaacatcg
    12601 acatatgcaa agttctcgga atcggtgttg cagtcagagt caaaacatcc acttgtgcac
    12661 gtaactgttt caatcgttcc ttatgtttta caccaaaacg ttgttcttcg tcaatgatca
    12721 gtagacccaa atcgctaaat tcaatatctt ttgacaaaat tcggtgggtt cctacaacaa
    12781 tatcaacttg acctgtacgc agttgttcga tggtttcttt ttgttgcttt cttgttctga
    12841 aacgacttaa tagcccgata tttacgggga aaccttcaaa tctttccagc atcgtttcat
    12901 agtgctgctg tgccaagatc gttgttggaa ctaaaaaggc tacttgtttg ctttccttta
    12961 tcgctttaaa ggccgctcga agcgctactt ctgttttccc ataaccaaca tcacctacga
    13021 gtagtcgatc cattggtttt tctttttcca tatcccgttt gatctccgct gcacttctca
    13081 actggtcatc agtttcagag taggggaagg cattttcgaa ttctttttgg taggcgtcat
    13141 caggtccaaa agcatatcct ttttctgact ctcttgcggc atataatttg attagatcgt
    13201 cagcgatatc ctcgattttt gaagagactt ttcgcttggt tttcgtccat tcacttccgc
    13261 ctagcttatt gatgcgaggc gctttggctt cagaggcgac atatttttgg atcagattca
    13321 gttgagtaac aggaataaac agtttgtcgt cgttttgata caaaatagtc atatagtctt
    13381 ggtgaacgcc atctacttct agcgtttcca tcccaatgta tttcccgata ccatgattgg
    13441 catggacaac gtaatctcct gcttttaact cattatagct tttcaatcgc tctgcgtttg
    13501 ttactgtttg acgtctcgtt tgttttttcg tcgttttttg gaaaatttct ttttctgtga
    13561 tagctactat tttttcttga ggaagttcaa aaccagcctg caaagctcct tcaactaatt
    13621 gtacctgtcc tctgatcaat gcattttttt ctgtttctac tactaatatg tcttcatctc
    13681 gaagcatttg ttctgctttg cgtattctgt cctttgtcgg aataaagatc acaacagtct
    13741 gtttttgctt gcgccaacgg tccatttctg ttttcagcaa tggcatttgt ccgaagaact
    13801 gttgcatcgt ccgatattga aaattatgga ttgcttggaa acgaagattt cccatccctt
    13861 tttggaagag tgagaaaaag gttgtggtga acttttcctt ctgcacgatt ttttgtatat
    13921 ctgctgaaaa tgtctgctca gaaaacaccc gcaattcgct gattttttga gtctgccatt
    13981 ctgccgcttc cctttcgatt tcccgatttg tttccatgat tcgctgataa tcatcaacga
    14041 ctagtaaact atttgaaggg aaataatcca agatcgtcac agattcttgg taaagaagat
    14101 ctgagtagaa ttttgcttct tctgtcggga cacctgcttg ccagcttgaa gtcagctgac
    14161 cgaagtaatc ttgcaaaaac tcgcggtctg cttcttctgt ggtcgcagca agccgttttt
    14221 ctagcatttt ttgcatttgc tctattccat gttctagatc ctctggtccg tagacttgtt
    14281 cactcgttgg ggaaacccag atttcttccg ttttttcgat tgagcgttgt gtttctgctt
    14341 caaaataccg catagaatct atctctacat caaatagttc tacacgaaca ggataggttg
    14401 tcgttaacgg gtaaatatcg ataatgcttc ctcgaatact gaattctccc ggttttgcga
    14461 ccatctcttc tcgtacatag cccatcaaag tcaattggcg aggaagattt tccacgtcta
    14521 tctcatcacc aatatgccaa ttcaattgcg cctgtagcca agttttctta ttcggcagtc
    14581 gtttgtgcaa agatgcgact ggcaacaaat agatacctgc ttttttttct tgaagtgcgt
    14641 taagcgttgc aactctctcg cctcgcgctt ctggagaaga aaaggccatt tcagcagaaa
    14701 gcacttcatc cactggaaat aaatggatct gatcttgcgg aatcacatgt tgcagatctt
    14761 ctgctaactg attcgcataa tacaaatttg gcatcagaat aatcatgttt ttatttgttt
    14821 tcttaaacgc tcgagcaaat agaagtgttt tcgctgagcc cgctaatcct gtgattagtt
    14881 gtctaggcat tttttcttct aaattgctga cccattcttt tacttgcgga tcttttccga
    14941 ctaattgaat aatatccatt ccttttcctc cttcctcaat tgaatcgatt catcgcatcc
    15001 acgaacgaat gcccttctat gagatattcg actgctttaa cagattgaca catgctttct
    15061 tctatcaaag gctgattttc tttgctgaaa ggactaagca catgctggac tactgttttt
    15121 ttcccttctg gcctgccgat tcccaccttg attcgatcaa agacattcgt attcaaatgg
    15181 gaaataatac ttttgatacc gttatgcccg ccggcacttc ccttttgacg gagccggatt
    15241 tttcccactg ccagatccaa atcatcgtag attacgacta attcctctgg ataaatccca
    15301 aaataagtca ttagtgggcc gactgcacga ccagattcat tcatgaatgt ttgtggtttg
    15361 actaaaagga tcttttctcc attatgaaaa aattcggcaa cttctgcttc gaacggattt
    15421 tttttgaaag tagcttgatg ctcgcgtgca attttatcca cgaccataaa gccgatattg
    15481 tgttttgtat attggtattt ggtacctggg tttcctaacc cgacgatcat tttcattttt
    15541 gttttccacc taattctaaa aagcagcaca aaaggctgga ctgctaatta gcggtccagt
    15601 ccatcgagct tttttctttt ttacacttgt caatgcatag tataacacaa aacaaggcgt
    15661 ttcggctaaa agagaatcgt taataaatga taaagaaatt aaaaatttct tcaaagttta
    15721 atgaaataat tgatatataa aaatagtgaa ataacgcaca tgtaagcttt tacatataat
    15781 acaaccttgt tatctgttat attttatagc caaatagcgt gacatggggc ttgagaaatg
    15841 ttagcataag catgggaaaa aacaaatcaa tggaaggatt gatactaaat gactgcagct
    15901 gcagaaaaaa aagatcatca aaaagttatt cttgttggag acggcgccgt aggttctagc
    15961 tatgcctttg ctctagttac tcaaaatatc gctcaagaag taggtattgt ggatatcaat
    16021 actgctaaaa ctgaaggaga cgcaattgac ttgtctcacg ctttggcatt tacttcacct
    16081 aaaaaaatct attctgctac ttacgcagac gcacatgatg ctgacttagt tgttattaca
    16141 gctggcgcac cacaaaaacc aggtgaaact cgtttagact tagtaaacaa aaacctaaaa
    16201 atcaaccgcg atgttgtcac acaaatcgtt gaatcaggat ttaacggtat ctttttagtt
    16261 gccgctaacc cagtagatat tttgacttac tcaacttgga aattctcagg tttccctaaa
    16321 gaacgcgtaa tcggttcagg tacctctctt gactcagctc gtttccgtca agcacttgcg
    16381 gaattagttg acgttgatgc acgtaacgtc catgcttaca tcttaggtga acacggagat
    16441 tcagaattcc cagtttggtc acatgcaaat gttgccggct tgcaaatcta tgaatgggta
    16501 aaaaacaacc cagaaatcga tgaagaagct atggttaacc tattctttgg cgtacgtgac
    16561 gctgcttaca caattatcga gaaaaaaggc gctactttct atggtatcgc agtagcatta
    16621 gcacgtatca ctcgtgccat cttagatgat gaaaatgctg ttcttccttt atcagtattc
    16681 atgaatggcg aatatggatt gaacgacatc tacattggtg cacctgctgt tatcaaccgt
    16741 caaggtatcc aaaaagtaat cgaaattcct ttaagtgaca gcgagcaaga ccgtatggct
    16801 gcttctgcta agcaattaaa agaaattcta gatgaagctt ttgctaaact agacgctgaa
    16861 taatctttga acatgacgga aaacatctat tcggtgtttt ccgttttttt attttatcac
    16921 ccttatggtt tctaaatttt ttcataaagt agagataacc ttcgtctttt cctctaaatt
    16981 atgctatcat gagaccgttc caccctaaac ttttacttaa ggagttgtcg atatgacaag
    17041 atcttcgcat cgaaaaaaat cgaaacatgt tgctttgctt tcagttcttg gtgttctctt
    17101 agtgctgatc agcttttata cctatcgcag tacatactac acaaagcatt ttttgccgaa
    17161 tacagaaata aatggaataa atgtcagcaa tctaacagtc gaaaaagcaa atgaaaaatt
    17221 aaaagaagct tattctgata aaaaactggc tattaaagaa gatggaaaag tctggcagga
    17281 agtaccaaaa tccgagctcg gctacaaaga tgatttcact tcggagcttt ctccgatcct
    17341 aaatgaacaa aacggatgga cttggggaat gacttatgtc tcagcggcag aaaaacaaga
    17401 aatagatcct gtcagtcaaa accaccaaaa actagacact accgttcaga cattgacaac
    17461 taagctgact gatttgaaca aagaccggac acctactact gatgcaacga tcgaaaaagc
    17521 aggtgactct ttcgttatca agcctgaagt caatggaaat acgatcgacg tcgatgctgc
    17581 ggtcaaacaa ttaaaaagtg cggtaaactc tggtaaagat acaattgaat tgactgaatt
    17641 caaagaaaaa ccaaaagtaa catctgaaga cagctcactg aaagaacaac tcgcatccat
    17701 gaatgctatc gcaaatgtaa aagctactta cagtataaac ggtgagactt tccagatccc
    17761 atcaagtgat attatgagtt ggctgaccta caatgatgga aaagtcgatt tagatacaga
    17821 acaagtacgt caatatgtaa cagatttagg cacaaagtat aacacaagta cgaatgacac
    17881 aaaatttaaa agtacaaaaa gaggagaagt tacggtccca gttggcactt acagttggac
    17941 gatccaaaca gacagtgaga cagaagcatt gaaaaaagcg attctggcag gccaagattt
    18001 tactcgttca cccattgtgc aaggtggcac aaccgctgat catccattga tcgaagatac
    18061 gtatatcgaa gttgatctgg agaaccagca tatgtggtat tacaaagacg gaaaagtggc
    18121 ccttgaaaca gatatcgttt ccggaaagcc aactacacct acacctgctg gagtcttcta
    18181 tgtttggaat aaagaagaag atgcaacttt aaaaggaaca aatgacgatg gaacacctta
    18241 cgagagtccg gtaaactact ggatgccgat tgactggaca ggtgttggta tccacgattc
    18301 agactggcaa cctgaatacg gtggagactt atggaaaacc cgcggttcac acggctgcat
    18361 caacacccca ccaagtgtaa tgaaggaatt attcgggatg gtcgaaaaag gaacgcctgt
    18421 attggtcttc taacaaaaat aatatataaa aagaaagcac ccgtacgatt ggtacaggtg
    18481 ctttcttttt attatctaac aatgtgctac ttacatttca gcagcagtaa agacttctga
    18541 aacatcatca tcgtcttcta gcttatctac tagacgttcc aattgctctt tttgttcctc
    18601 atttaaatca atcgtcgttt gtggaatcat cgtcaattct gcttgcgcca aagtgaactc
    18661 tttttccaac tcatctcgta cagcagcaaa atcttctggt gcagtataaa tctcgaatac
    18721 ttcaggagaa gtttgcagat cttctgcccc cgcctctaat acatcctcaa acatcgtctc
    18781 ttcatcaaca gtcaacccat cgcgttcaat agcgatatat cctttgcggt caaacaagta
    18841 actgactgaa cccgtttctc ccagtgatcc accgtttcga gtaaaagcta ctcggacatt
    18901 tgtcgctgtc cgattacggt tatctgtcaa tgcatggact aagattccta ctccacccgg
    18961 accatatcct tcatacgtga tttcatcgta attcgtttca tctacggcac tcgtagcctt
    19021 tttaatcgcc cgttccacat tgtcgttagg catatttgca gcttttgctt tgtccacaac
    19081 aagccgcaaa gctggattca tagatggatc aggaccgcct gctttagctg ccatataaat
    19141 ttcacgagaa agtttctgaa agactttccc tcgttttgca tcttgggcat tttttcttcc
    19201 ttggatatta tgccatttac tatgtcctga catgattttt cctcccttgt tcttttgaga
    19261 atacacttct attctagtac tatttcacaa aaaaacaaag ccacagccaa tctataaacg
    19321 cttcttgaat gccgcaaaaa gcacacataa tatcacagca gtcagagcac cgatcgaatc
    19381 caacatgaca tcttggaaca taggtgttcg tccaccggtc atcatctgat ggaattcgtc
    19441 caaacctgcg taccctgttg ctgaaagcca agcaaggatc gctgtcagcc accaaatttt
    19501 tagcttgggg aaaacaccta aaaacaagct gcctcccaaa ataaaatagg taccgaaatg
    19561 tgcgcccttc cttaaaaaga actctaaaaa tttggcgtag cccagatggt tgatactcac
    19621 catacttcca ccataattaa aacgtatacc cgctaatgtg tctttaaatg gctgattagg
    19681 cagccagctt tctaatcgcg aaacttgtga ttgctgtccg taagtttgag aagaactgta
    19741 aaataagatt ataacgacta tcagtgcgat tactaaataa atatttccgt ttttcatttg
    19801 tttttttgaa gaattcataa gtcacctctg tattttatct tagacttttt ttgaagaaac
    19861 aacaatcatt ttcatagaga cttcttccat aaaaaagtgc tatacttaat tttgtattac
    19921 aatatgaagg gagttttttc atgagttatt cattaaattg gaatctagat tctatttttt
    19981 ccggaggcag tcattctgat gctttgaacc aacggatgaa gcaattggaa gaccaaatga
    20041 acgagtatta tcaccgcgta acaaaatggt cacctagttc tgacaatgca gagcagttaa
    20101 acgctattct tcaattgcaa gaaacgatta cgaatggttt tacccaatgc agcagctata
    20161 ttactgcatt gctttctgcc aatgtcaatg attcagatgc aaaggtctta tcaggcaagc
    20221 tttacgcaat gctgcctcgt ctgcaatcag ccgaaactgt attgtcaaag aaatttgcag
    20281 aaatatctga caatgattgg aatcagatgc tttctcaatc ttcgtttgaa acaattgctt
    20341 ttcgtttaaa cgagattcgt cgtgatggct cacaattatt atcagaagct gaagaaaaca
    20401 ttataaatac gctttcttta gatggtctaa atgcttggag cagtcattat gatacgattg
    20461 tagccagcat ttcgattccc ttcgaacaag atggacaagt agtcgaatta tctgctggac
    20521 aagccttcaa taagatgatg ggcgatccag atccaaaagt cagagaaaca cttttcgcag
    20581 catgggaaga agcctggaaa gaaaaggcac ccctcttcac ggatactttg aatcatttag
    20641 atggttttag actttctgac tatgaacttc atggtgtcac agattttcta caaaaaccat
    20701 tagagtacaa tcggttgaag aaagaaacat tgtctgtcat gtgggataca atccagaaaa
    20761 acaaacaacc ccttgttaat tacttgacta gaaaagctaa tcttttcggt aaagaaaaaa
    20821 tggaatggca agatcaagat gcacctatta ttttaggcga tttgaaagaa aaaaccttta
    20881 gttttgacga agcagcagca tttattatcg aaaactttaa caaattcagt ccaaaaatgg
    20941 ctaaatttgc ccaatctgct tttgaaaaga gctggatcga agcagaagat cgtcctggga
    21001 aacgtcctgg tggttattgt actgagttac cagaaacaaa agaatcaagg atctttatga
    21061 cctacagtaa ttctgttaat gaggttgcga cacttgctca tgaactagga catgctttcc
    21121 atagcagcac gatgtgggat ttaccttctt taaatcgcga atatgccatg aatgtcgcag
    21181 aaacagcaag tacattcgca gaactgatcg tagccgatgc tacattaaaa gtcgcaaaaa
    21241 caaaagaaga aaaaatcaat ttgctagata caaaactgca aaatgcttta gctatgttca
    21301 tgaatatcca ttcccgattc atttttgaaa atcgattcta tgaagcacgg caagaaggat
    21361 tagtctcaga agataagatc acagagatga tggttgaggc gcaaaaagaa ggctatcaag
    21421 gagctttagc tacttaccat ccatatttct gggctgcaaa attgcatttc tttattgatg
    21481 acgtaccgtt ttataacttc ccatacacat ttggctacct ctttagtttg ggcatctatg
    21541 cttacgccaa ccaaaaggga gcaaattttg aagaagaata tatccattta ctacgcgata
    21601 ctgcctcaat gacgacggaa gatcttgcga agaaacattt gaatgtcgat cttacccaac
    21661 cagatttttg gcaagcaggt atcgacatgg tgactgaaga tatccaaacg ttcatggaat
    21721 tgacagaaga atttatctga tttctatttt atcacaataa aaaaagagtt agtccagaat
    21781 gggctaactc tttttgatta atcattctta catgctgaca gcaaagtcag gggcaaacca
    21841 ttgaactgaa ccaactttta cgctttcgcc tggttgagga gcatggatat attgtcctcc
    21901 gcctaaagca atcgctacgt ggtaagttcc gccttgtgac ccccagaata acaagtctcc
    21961 agcttttgct tgagaaactg aaatttttgt tccagctgat tcttgaggaa ctgtccaacc
    22021 accgatgtca cgaccagtta cttgcatgta aacatagcgt gtgaaccctg agcagtcaaa
    22081 gccacttgga tctttaccgc cccaaacata tggagtacca atatatttgt aagcttctgc
    22141 tacgattgct gcaccattca cacttccaga aggagctgga gcaggtgtta caggttttgg
    22201 ttgttcaggt gttggtgttg gcgttggagc cggagtacta cttcctgtgc cgtttcctgt
    22261 atcaacactt tgatctgttg atggtgttgt aggcgcaggt gttgttgatt cttctgttgt
    22321 tgaagattca ggcactgttg ttgattcttc tgttgctgaa gattcaggca ctgttgttga
    22381 ttcttctgtt gctgaagatt caggcgctgt tgttgattct tctgttgctg aagattcagg
    22441 cgctgttgat tcttctgttg aagattcagg tgttgttgat tcttctgttg ctgaagattg
    22501 tgtagctgat gatgattctt cagtcattga agattgtgta gctgatgatt cttctgttgc
    22561 tgagctttgt gcagtagatg aagcttgagt agcttgtgct tcagcctctg cttgttcgcg
    22621 tgcttctttt tcagcttttt cttgtgcagc ttgttgacga gcttgttctg ctagacgttg
    22681 ttgttcacga atacgagctt gctctgcttc agcttctgct ttttgacggt tcaagtcagc
    22741 tttcttgtct tcagcagttg cttgttcagc agctaatgaa gttttcagta cgttcaaatc
    22801 agcttgttta gataaaagat cgcctttttg agattccaaa gcagcttggt tttcagctaa
    22861 ttcttttagt ttagcatcgt tttcagcttt tttgtcttct acagcttttt tatcttgttt
    22921 ttgttgttcc atcaagtcgt tgtttgcttt taccatcgtt gtcattgctt gaacgcgtcc
    22981 aatagcatct gctaatgaat cagcattcaa tacagcatcg atgtagtttg agcttgtgtt
    23041 gcttacttgt gcttcgcgtg cttgtttttg gattgtatct tcacgttttt caatacgttc
    23101 ttgtaaatct gcaatgtctt ttactaattg tgcagattct tgacgcaatg tatcttgttt
    23161 tgctaatagg tcttgtgctt gtgtgttgat ttcagaaact tggctttcta aggcatcgat
    23221 ttgtgattgt gcatctgctt gttgattttt caagtctgca atcttttgat cttgctgttg
    23281 tatctgagaa tcaaaatcgt ccgccgcggc agcgatcggt gatgctacgg cagtcaaggt
    23341 cattgaacat accattactg ctgatattaa actctttttc actcttcatt cctccgactg
    23401 gcttaattta ataaatatct aaatatattt aagtctttct taacgatata aaaattgtac
    23461 catagcagtg tgtcaacgat ataatagtta tgttacaaaa atgtttcaaa acaactttta
    23521 aaaatgacaa aactgttcgt ttcagaaaat gatcatgaaa aagccgcgtt aagtctagca
    23581 tttcttaaga taacaacgat tctttttcgc tttcgaccta aaaataaaaa aagaaattat
    23641 tcatcactga ataatttctt aaagggaaaa atgaataata caaatataat catgttcaac
    23701 agcagtgtag gtcctaaaaa ccttgtaata aaatacgtgt tatttactac tgctaattta
    23761 aaaatcaact ggaccaccat cgtaaacaat tcataacccg tgacaaagat gatcatactg
    23821 aaaaattcag taaagatgtt gacatggata acgtctttca ttacatacat caaccataca
    23881 attaaaggga gagctactgc atagataccg ataacgccaa tatagtaagc gtcatagata
    23941 gccccgagaa caatcgtggt aatcagtaaa taacgttttt caaacgccat actgcaacat
    24001 aataatgcca atatcagaaa gtgggcattt gacatatagg tgcctttcga ccactcccct
    24061 agcattcttg ttaaatgacc atctatcaac atcaaaaaga acaaaacgat tggcagatag
    24121 tacttcattg tttctttctt caacatggac taatcctccg ctagccgttg gacaatcgtc
    24181 acaactgaca cgtcatacat ttctgcataa ggtttcacat aaacttcccg atccagccca
    24241 taactatctg gtttcgtttt aataaccgta ccgatcggca agttagctgg agaattccct
    24301 ccaagaccgg atgtctggac aacatcccct tctttgatat ccgtatcacc agttaattgg
    24361 gtcaccacta aggcatggag cttttcatca tagtttttaa gcaaaccaaa cgcttcgcca
    24421 ttagccgaag atacccgtac tggaaaatga ttggagcttt cattagagga tgacagtaat
    24481 tcgattttag acgaagccgt attgacctcg atcactcggc caatcaatcc tttttgcgac
    24541 atgactgcca tatttgcttc gataccgtct ttagaaccct tgtctacgat cagcatgtcc
    24601 tgccaactgt caggcgaacg agtaatgaca tttgccgtta ctttttcgta actagtcagc
    24661 gtctgattca actcaagttc ttttttcaac gcttcgattt ctctctcgta attcttgttt
    24721 tgctgtgaaa cgtcatcata gctatcgatt ttttctttta gccgctcatt ttcggcataa
    24781 gttgaaaaaa gattatggac agaatctact ccatttcgta cccaccgtac tggggcagag
    24841 attgttttat caaccattgc aacactgtca ttaacgatgg attggaagaa attgggcttt
    24901 ccttcattcg ctcgctgcgc agcggtcaca cttagtatcg tcaccacgat gataacaata
    24961 accaaggtaa taataatatt tttattagga ttgaacttct tcacaaagac acctcgaatt
    25021 aattagactc ttgtgttcaa ttttatcact aaatgccgtg aaacaaaagg taagttgctc
    25081 ctcttaagct tttttttagc aaataataga ttctgtcatt tttagcctga aagacaaatt
    25141 tttttatttg tttatggatc aatctttgct ttgaataact gcaatcatac catctgaaaa
    25201 agaaaattct gcggtatctg aaagaaattc gttacttgca taagatgtcg gatattctac
    25261 ttctttattt tccaatacat acttgctgcc ttttaatgta agattcgaga cgggagtcaa
    25321 gcagcaataa gctaaatact tcatatctgg tatctgtctt actatatgct ctccaggcaa
    25381 ataataagac aaataatttt gacaatctct gataataagc tgatgggcaa agggtttgaa
    25441 gcgaggttcc atacctaacc agagattggc taaaagatga tccaatcttc cgcccgtagc
    25501 tccaatcaaa gtgacttccg cttgcgggta acgttcaaat gtttttaaga tacctaactg
    25561 tgtatctgta tcgtcttttt ctgcagggga acgggtatac tctttggctt ttgcaaatac
    25621 ttccttctgc tcttcgttcg acaatgaatc aaaatcaccc actgccagat ctactgggta
    25681 gcctgcttga agcaggtaca gcgcaccacg gtctatcccg acataggcat cgtatttgga
    25741 cagcagagac tgcggccagt tttgcggatt acctccagca gctaataaaa ttttcattta
    25801 gtctaatgcc tcttttaatc gttcgatttg tccgactgga ttttcggctc catagatata
    25861 tgatcctgca acgaagacat ccgcccctgc atctttacag atttttgctg tttctggaac
    25921 gattccgcca tctacttcga ttgcataagt ccaattgttc tctctacgta gatcagcgag
    25981 ttccgtaatt ttttctactg tttcttcaat aaagctttgt ccgccgaacc caggattgac
    26041 agtcatgact agtacttgat cagccaaagg caaaacatgt ttgatcatgg agactggtgt
    26101 tcctggattg ataactactc cagctttaac tcctaagctt tttgtcattt gaagtgcccg
    26161 atgaatatga ggagttgctt cgacgtggac agtaatgata tctgctccag cttttgcaaa
    26221 tgctggaatg tagttttctg gatcaacgat catcagatgg acgtctaacg gtaatttagt
    26281 aacaggacgg attgcctgaa caatatttgg ccctaatgtg atatttggga caaatcggcc
    26341 atccattaca tctacgtgga tgtaatctgc gcctcctttt tccactaact caatgtctct
    26401 ttgtaaattg gcaaaatctg cactcaaaat ggatggtgct atcttcattc ttgtttcctc
    26461 ctattttcgt ttaccttctt tttttgcata cattggtttt cttttttcga tttcttgtaa
    26521 gaattgcaaa taattgtcgt aacgtgtctg tgcgatacca cctgtttcta ctctatgttt
    26581 tacttcgcag ccaggttctt tagcatgcat gcactctcta aatttgcaat ggacagaagc
    26641 ttctacaaat tcaggaaatt gtctcggcag ttctcctgct tcaattgtca aaaagtcaat
    26701 cgagctaaat cctggtgtat ctgctactaa cccgccatag ataggaatca gttccacatg
    26761 acgtgttgta tgccgtcctc ttccaagtgc atcagaaatc tctcctgttg ctaaattcag
    26821 ttccggtgat atttgattca gtagcgtcga ttttcctgct ccagactgac ccataaagac
    26881 cgatagccgt tctgggaagt aacggatcag ttctgtcgta tcacccgtat gattgggtac
    26941 aatcaccgga tagcctattt tagtataggt ttgcttgatc tcttcgattt tttctgggtc
    27001 gtctgacaag tcggtctttg tcaaaaaaat aatcggttcg atcgactcgt attccaaggt
    27061 aactagaaag cggtcaagta gattataaga aaatgcaggc tctacgatac ttgtgacaat
    27121 gattccaaga tcaacatttg tgactggtgg gcgaactaat tgattttttc tcggcaagat
    27181 ttccagaaga tagccgtctg tttgattttc actctcaaag atcacctgat ctccgacaag
    27241 cggcgtgatt ttccgattcc ggaaatttcc tcttcctctt gtttgatagg tctctccgtt
    27301 tgcgtataca tagtaaaaac cgctgattgc ttttctgatt tgtcctttga taagtgccac
    27361 ctccgttttt gtttatttta ccatacgaag aggaaagtag gtgttattcc atgcaaactt
    27421 ctcaaagtat atggcttgaa aattgatcaa aagagataga aacacaaaaa agagaatgca
    27481 acaaatcaat gtcgcattcc cttctgatat attttattca gcacttattt tgaactttct
    27541 gaggtgctag ctgatgaact tgtggagctg gaagattctt cttttgaaga gttgcttgtg
    27601 ctactggagc tacttgagct gctagaactg tctgaagagt ctttttcaga actagaagac
    27661 gctggatctg gtcctttaga gtaaattacg ttcacaacca ttcctttggt aattgtcgtt
    27721 cctgcccctg gtactgtacg aatcacttta tctttatcca ccgtgtttga atattcggaa
    27781 gtctcatgcc cgatatattc tgcaccgaca ctagctaaat aactttgtgc ttcgcttttt
    27841 gtatagccgg agatatcatt caatttaggc tctgttcctt ggcttacgac aaaattgatg
    27901 taagtttctt ctgctacaac ttcacccgag gctggatcct gactgatgat cgaacctgat
    27961 ggtacagtgt cgctatagtc ataagtagca ctaatattat tgatattgaa tccttgtgta
    28021 acaagccaat tacgaacagt ttcgtagttt tctcctacat gactactcaa agtcactgtt
    28081 tctggtcctt tgctgactgt gaaagtaatc gtgtctgttt taggatcgac ttctgtatct
    28141 tctgatggag attgcgaaat gatcattccg ctttctacct ctgaactgaa ttcctcttct
    28201 ttttgaatca agtcagcaga aaaccctaat tctttcaaac ttgcttcggc atcttcataa
    28261 cttttaccac tgtaatcatc taatttgatt tttttcgtgc cgctactaat atacagagtg
    28321 acttcgcgtt tttgcttgac tgtcgttccc gctgccgggt ctgtcttcac tacattacct
    28381 tcttcgattt tgtcatctgc aatttcttct gtttttgttg ctacttctaa tttcgctttt
    28441 gcgagtgttt ctctagcaga agcttcagaa agatcagaaa catcaggaac aacaacttct
    28501 cctcgcccgc cagaagcaaa gaatacagct gttccgattc ctaaaacagc aagaatagct
    28561 aataggatca gccaccattt tttctgtcct ttctttttag gatcaggcag aacttcttcc
    28621 tcctctggta aggtttcgtt ttctggcttg tcttttggca gaggcataga tttgaatgaa
    28681 tcaggcattg gtgcatcttc cgtaaggggt gtgataactt ttgtttcatt atccatcaca
    28741 tgaggctgcc atttttcttc gtttgcacga gctggtgata atactgtaga aagatcatca
    28801 gacatttcct cggctgactt ataacggtct gcaggttctt tagccgttgc ccgtaaaatc
    28861 acgttttcca gtgcttgtgg cacatttgga tcaagtgctt ttatagatgg aagatcatct
    28921 tgaaaatgtt ttaaagcaat tgttacagca gattcaccat caaacggtac gctacccgtc
    28981 aacatctcat aaaggatgat ccctaaagca taaatatctg actgcttcgt tgccatactt
    29041 cctctggcct gctcagggga cagataatga acagatccta gcatcgtatt cgtctgcgtg
    29101 atcgatgttt cagataaagc gatagcaatc ccgaaatccg tgatttttac aacaccttca
    29161 ttatcgatca gtacgttttg gggtttcaaa tctcggtgga tgatttgatg gttatgagct
    29221 aaagaaatag cagaaaggat ctgctgcata atatttactg ctgtttcata aggaacagga
    29281 taatgtgttt ggatatatcg tttcaagtcc attcctttga cgtattccat caccagatac
    29341 tgcatgttgt cttcttcacc aacatcgtaa acactaacaa tgtttggatg aacgagttct
    29401 gttgctgcta aagcttctct ctgaaatcgt cgaatcgcag tctggtcatt ttgaaagtca
    29461 aatcgtaaga ctttaactgc tacatcacga tccaagatta aatcgtgcgc caaaaataca
    29521 tttgccatac caccgctacc gatatttcca gtgatttgat aacggccatt taattttttg
    29581 cccaactcga tcatacactg tcctccttat attcgataag aagaacggtg atattatccg
    29641 ctccgcctgc ttcattggca cgatcaatca gctcagttac tttatgagac aatgggcctt
    29701 cttgattgat gatcgttcct atttcttctt cagacagcat gttcgtcaag ccatctgaac
    29761 ataacagcag tcgatctttt agttgccaaa gatgagtaga aacatctact tcgactgttc
    29821 caggcatgcc gacagaacgt gttaaaatat ttttccttgg atggttcact gccatttctt
    29881 cgctgatttc tcctgatttg actagttcat tgactaaaga atgatcctcc gtcaattgca
    29941 tgattttatc ttcacgaatc aaataagctc tgctatcccc aacattggca atcgtgaacc
    30001 agtcatctga cagagcggcc gctacgattg ttgttcccat accgttatat tccggctgtt
    30061 cttgtccacg ctgataaatc agcatatttt cttcttgaat cgattgaatg aaccattggg
    30121 cgattttttc atcgtcaaca gcttcttgtt tttcccaagc ttcgcctaga ttcgttaccg
    30181 ccatctgact ggcaatgtct ccggcacgat gaccacccat cccgtctgct aatacagcaa
    30241 gcttgagacc tgaacggctg gtaaatacac tggcatagtc ttgatttgtg ttacgtcgtc
    30301 ttcctacatc tgattgatat tcaatctgca ttttttcacc tcattacttt ttgcgcaaac
    30361 aacaaatgaa aaatccatct gtgtaaaact gatgcggata caaagtcaac attttctctt
    30421 cgattgatga ttgtagcata ggattggtca aaacatcaat cctctcaaaa tcagggtgtc
    30481 tttccaagaa agcagaaaca acgtcttggt tttcttcttt taagatcgta caagtgctat
    30541 aagtcagaat accggaagac tttaaagttg gtgcgcagct ttctaaaatt tccaattgga
    30601 tttttggtaa attcgctaat tcatccggct gttttttata acgaatatct ggttttcgcc
    30661 gaagcagccc aagacctgaa caaggcgcgt ctactaaaat ccgatcaaac tgctctgctt
    30721 cgaactgttt actgacttct ctagcatcca tcttttgagc gtagacagca gaagagacac
    30781 ctagacgtgc tgcattatct tcaatgagtt tgactttgtg ttcgtgtaca tctaaagcga
    30841 ccacttctcc accgcatgac ggatctaaaa aagaagcaat atgcgtcgtc ttacctccgg
    30901 gtgctgcaca ggcatctaag acatgatgtt caggctcgat ttgcatagac ggcgctacaa
    30961 gcatcgaact ttcatcttgg atcgtcatga cgccatcgtg gaacaatgag ctagaagcta
    31021 aatgcccttt tttcgctact ataccgtatg gactgacttg gcttttttca gctgtgatct
    31081 cttcttcttg caaaacagtg atggcctgat ctctggaaag tcggcgtgta tctactcggg
    31141 cactagcatg gctaggctga tatagcgata aaccgagctt ttcagtttct tcgtatccga
    31201 tttgatccac cagtcgtttc gtcatccata gaggcaggct gattttgaca gaaagtcttt
    31261 cgataggatc agcaatgcct tgcagatctg gtgctccttg acgctgataa ttcctcaaga
    31321 caccatttac aaatttccct gtcccaggat ttccttttac ttttgcgatt tcgaccgcct
    31381 cgtttaaaat agcatgtgca gggactttat ctaaaaattc taattggtat acagaaagat
    31441 aaagaagcat cttgacccag tcatccactt tttttgcttt agcgatcaat ggtgcaacgt
    31501 aaaattccaa tagtcgctga tggctaatcg taccatagat caattctgta aataaaccca
    31561 catctttttg atttagctcg ctttgtttga tcatctcatt caacaaaaga ttcgagtagg
    31621 cgccaccctt gttcactcgc tctaatgtca gtaatgccat atatcgtact gattttttca
    31681 tttttttagg aatttttttc attatttcac ctgctgacca atctgaactt gctgaccgct
    31741 tccgttaagg aaatcatgta cggcctgttt tcctttacca gctggctgta attcattgat
    31801 ggctaagacg gtctgtttac cgcaagcaat ccatagattt tttttgtctt tccggatgat
    31861 cgtaccaggt gctttgtctg tagtttctgc caatacttca accgataata atttccagcg
    31921 tatgccctca taggtcgtga atgcaattgg ccaaggacgc attccgcgta cttggttgtc
    31981 aatttcttct gcagttttat gccaatcgat tgcttcttgt tcccgtgtga tgtttggcga
    32041 aaaagttgct tctgactcgt cttgaggtac tggtttttgt ccatccaaaa tattgggcaa
    32101 tgtttctagc aatagctttc ttcctaaaag gctaagcttt tcaaacatcg tccctacatc
    32161 atcttgttta gtgattggta tgctttcttg cgcatagatt ccgcctgcat ccattttttt
    32221 gatcatttcc atgatcgtta caccagtttc tttctcccca ttcatgatgg cataatgaac
    32281 aggcgcacct ccccgatatt taggaagtaa agaagcatgg acattgattg cccctaattt
    32341 tggtacttgc aataactttt caggcaagaa ttggccaaat gccgcagtga cgatcacatc
    32401 aggcaccaat tcaatgattt cttccatttc tggcgaaccg gagattttct ctggctgcag
    32461 cacacggata ccgtgcttca gagccgcttt ttttaccggt gtcggcgtaa ttactcgttt
    32521 ccgcccaact ggacggtcgg gctgtgttac cactgcctgg atctcgtaac ctgattctat
    32581 cagcccttca agaatcggca cagaaaaagc aggtgtgccc ataaatacta gcttagtcat
    32641 caagatgttc ctccatatat tcttcaagtt cttcttccgg gatctgctgt atcattttct
    32701 caatgaacaa gataccgtct aagtgatcga tttcatgctg gaaggcacgg gctaaatagc
    32761 caaaagccgt cacttctatc tcttctccgt ctcgatcata ataacgcacg gtcacttcat
    32821 ctgctcgctt gaccgttcca tagacatgcg gaatactgag acaaccttct acgtcaaggc
    32881 tttcaccttt tgcttcgatg atttctgggt taatcagttc aaatttctcg ccttcatcta
    32941 cttcgatcac agcaattctc ttgttttgtc ctacttgagg agcagcgatc cctattccgt
    33001 cattcgcaat cattgtctca tataaattgt ctaataaagc gattgtctcg tccgtgatta
    33061 catcgattgg ctgagcagtt ctttttaatt tatcattagg gtggatcaat ataggatagc
    33121 gcataatttg gccctttctt aaataaagtt taatggttcg ttgtcaattg ccacaaaaag
    33181 accttgtcgc tgttctttct ggcttccatt caaaatttca tccaaaacat gaggaagatt
    33241 cggttcatgt ttatatttga tgattagttg ataataatat cggtttttca ctctcaaaat
    33301 catgctgggc gttggcccta atagcaagct ttgagggctt aacacttctt ttagctgatt
    33361 ggcaatctga aagattttct ttgccgctac ttgttcttca ggatggctgg cggttatttt
    33421 cacagtaaag taataaggag gatagcctcc acgatgccgt acatgcattt cctgctgata
    33481 aaactgctca taattttgtt ttttagccaa ttctatggcg taatgttgag gattgaatgt
    33541 ttggatcacg acttcgcctg ctttttccgc tcgccctgct cgtcctgaaa cttgggtaag
    33601 caattggaat gtatgctcac tagaacgaaa atccggtaaa ttcagggagg tatcagcatt
    33661 caacacccca actaatgtca cttctggaaa gtccaaacct ttagcaatca tttgtgtccc
    33721 taataatata tctgcttctt ttgcaccgaa tttttgtaaa atctgttcgt gtgccccttt
    33781 tcttcgagtg gtatctacat ccatacgcaa aatcctagct tgcggataaa gttctcggag
    33841 ttcctcttct actttttgag tacctgttcc atagtagcgg attttattgc cgccacaatt
    33901 aggacagcga ttgggaatag gttcttcatg tccgcaataa tggcagcgca ttgaacgtgt
    33961 atccatatgc agtgtaagag agatatcgca attaggacat ggaagaacaa atccacagtc
    34021 cctacacatc acaaaagacg aatatcctcg acgattgagc agtaggacag tttgttcttt
    34081 tttgtctaat cgattttgta ttttttcctg caaattagca gaaaaagtag aggtccgatg
    34141 attctgaaac tcttcacgca tatctacgat ctcaatagct ggaagctgtg cagctgcttt
    34201 ggctcggtgg tttaactgca ataactgata aacgcctttt tgagctcgtg ctcttgattc
    34261 taaagagggc gtcgcgcttc ctagaactat tgggcaatga tgatatttac tgcgccaaat
    34321 tgctagatct ctcgcatgat aacgcggtgt ctcatcttgt ttgtaacttg attcatgttc
    34381 ttcatcgata atgatcagcc cgatattttt cagcggggca aaaatagcag atcgtgcgcc
    34441 tactactact tgcgcttctt cccgctcaat cttgcgccat tcatcatatt tttcaccttg
    34501 ggaaagtccg ctatgtaaga ccgcaactga ttctccgaag cgtcctttga atcgctcgac
    34561 catttgcgga gtcaatgcga tttcaggcac taacataata gccgttttat tttctgacaa
    34621 aacatcagcg attgcctgaa gatatacttc tgttttcccg ctgccagtga ttccctccag
    34681 caaaaagacc tgatcttttt gctgctgacc tgctgtgatg atttgttcga cagcattttt
    34741 ttgttctgca ttcagttcca atgccgtcgt ttggtcaaat actcggtctt tataagggtc
    34801 gcgataacgt tctgattcta taaactccag ccagcccttt tcttttcctt gattcaagac
    34861 agcagtactg attcctttat ttttgaaata agcaattggt tcttcttggc tcagttcaga
    34921 taaacacaaa agaagttctt tttgtttctt ggcattttgc cgtaattttg cccattcttc
    34981 ttcgatttgc ttttcagtta acaaagaacg gaccaaacga atcgttttta ctttatttcg
    35041 tgtatggact tcatatttga tatctactaa ttgctcttgg cgccagcgaa tcaattgaga
    35101 aaggctgcct tcttcttctg cttccttcca ggaaatcact tctcgctgat caaacaatac
    35161 ctgaacttct ggtgtgtctg ccaaaggata gatcaattta tcatattctg ctttcatcac
    35221 actcggaagc atcgtttgta gacaagtgat tttgaatgcg taagtaattt ttttcatata
    35281 atcagctaat gaaagtaatt cttcattgac caccggagca aggtctagca aacgaataac
    35341 tgccttcaaa gatggattag ctgattcttc tgatttttgg atagccataa caaatccttg
    35401 gacatgacga ttgccattac caaaagggac ttctactcgc atcccgactt gcaaagctgt
    35461 ttccatttca gagggaacca aataagtgaa tggctgatcg gtctgcatag taggtacgtc
    35521 cacaatgact tcagctgtta atgtcatggt tcgtttcctc ctttttttgt cttttcttat
    35581 caagcgacaa aaagttcctt gcctatttta ctagagatcg atggatttgt cttatcttct
    35641 gccaaatcct aacaaaaaat taacagcaga taagaaaaaa aagaactgtg tcaaaaagtt
    35701 cagacacagc cttttctacc agacaataag tggcgaatgt ttgaaaagga aacagctggg
    35761 tttgcttttc tttttagatg ttcgctctat ttttctttat tacatttttt gctcttcacg
    35821 gatacgtgat tccaattcgt gttgttcacg ctctttttgt gcttgacgtt cctcttcttc
    35881 catcttcaaa cgttcacgtt ttaattcagg atgtggatca ttgactacat ttcctgcatc
    35941 gatttcttct aaagcttgac cgacgctttt tactgaatca aaagaatcta gagtaggctg
    36001 tgcacttgca tccaattcat gcgcgcgttt acttgctaaa atcactagag aatattttga
    36061 atttacacga tctaatagtg agtcaattga aggttttaac atcataagac tacatctcct
    36121 ttaacatttt aatatattta ccgattacgc gatctactcg aaaatgttca ctggcaataa
    36181 tgtttttgat tcgttcaact gctagcggca cttcatcatt tacaacagca tagtcgtaaa
    36241 gagccatcat ttcgatttct tcttttgcaa ctttcattcg tttttcgatt acttcatctg
    36301 catctgttcc tcggcctacg atccgtgatt ttaattccgc taaatctggc ggagtcaaaa
    36361 agatgaatac accatcgggc actttttctt tgacttgttt tgctccttgg acttcaatct
    36421 ccaagaaaac atcttttcct tcatccaatg tcttgttgac atatgacaaa ggagttccat
    36481 aataattccc gacatattct gcgtattcca gcatctctcc agcttcgatc attgattcaa
    36541 actcttcttt gcttcggaag aaataatcaa cgccttcgac ctccccttca cgcattttac
    36601 gggtagtcat tgagatcgaa tactgaaaat cattatcctc actctcaaaa attgcttttc
    36661 gtactgtgcc ttttcctaca ccggatggac cagacaacac gattaataat ccacgctctg
    36721 acatgacgac gtcctttcaa ctagtctttt tgtacttatc gtttattttg cacttttttt
    36781 ctgcaacttt caaggttatc tttaattata gctagaaatt ggtaaaaaag ctaccctgta
    36841 ccaagaggtc gtaaaaaagc tgtcctgcat caagtaataa gaacagccaa acataaacag
    36901 cttctcatgt ttttcgtttg gttggggtta ttatcgcaga tgcaagcttt tgaacgccgt
    36961 gtataagagg tcgtgaagaa gccgattagt ttcgagtatg aagaaaaatt ttgtgaaaat
    37021 agtttctcac atttttgcat aaatttggct taataccgag aaaatggttt ttgaacatca
    37081 cttattcaaa ataaaaaaag attgtgacac gaattttgtc acaaccttta aatgtattcc
    37141 tagagcaaag aagctaagcg aagaaatcca attctgttta tttattgtat ttctttgttc
    37201 agcatccttg ctaaaagccc atattggaca aagtattcac tacacccatg atctcatctt
    37261 ttcgagaacg tgctttttct gtcggatctt ctacctcttc tgtgtcaatt cgaacaataa
    37321 atttccgatt catcgtcacg taagcaccgt cgttgatcaa aataaacagt tcgttctcat
    37381 tatagtctgc acaggcatct ttccatacgt caaagccgtt tttttcagaa gggatatccc
    37441 gtttaaccac agtttttcca cttaattcgt ggaacgttac gtcataatat ttcattatct
    37501 ctacctcttt cgtcattcaa tattttgtac ttgttctctg attttttcta agatcgtctt
    37561 agactggacg acttgatttt taatttcgat tgcatttgat ttggaaccga tcgtgttgat
    37621 ttcccgattc atttcttgga tcaggaaatc taattcccga cctacaggac attgtgcttc
    37681 gataagttca tctagttttt gtacatggat cgccagacga tccagttcct cgtgaatatc
    37741 tccgcgttcc aacaagatgg ctagctccgt caacaaccgt tgctcatcga ctttcgctcc
    37801 aagaaattcc tccagctttt tttgatacct tatttgaaat tccttttcat agatttctac
    37861 aaaactatcg agttttttta gtacttcttt gaattcttca gtattctttt tcaacactaa
    37921 agctaaagct tgaccttctt tttctcgact cgcctcaata gaatcaagtg cgcttttcaa
    37981 tgtatctaga gctaactgtg ccaattcttc catgctctct tccggttttt cttctaccgt
    38041 tacgaagttt tcgtccagca cgaagcgttc cgccatccga ctaattgaca cttgattttg
    38101 actaccgtat cgttgttgaa ttccgtctgt caattgagtg ataagtgaat caatcaattc
    38161 ccagttgatg acgatctgtt tttcgttttt gccaatataa gctagattca caaatacttc
    38221 gattcgaccg cggcttaact gctgtttaat aagctgacga aaatcgtttt caacaaagtt
    38281 caggatttta ggacttcgta tttgaacatc tagaaaacgc tggttgacac tttttatttc
    38341 aatatctaac tgatacgctt ttgtttcgcg gatggctttg ccaaaaccag tcatactttt
    38401 cattcgacag ggtccttcct cattacatat tttctattgc tttttgcagt tgttcaaact
    38461 cttcgttcgt caatgtcagg cctttcccca ttttttcatg gtctggcgcc caatctcgaa
    38521 gatcgaattt tggcgggcga ccattccagc tgactaggtt cagttcttta cgccacccct
    38581 tgttgttttc tgacaatata gcgatttctt ctacgatttc atatgaaaat tcttgtgcca
    38641 tggttgttcc tccttgagat aatataaata taggatcagt aatgtgtcaa ctggttgctt
    38701 aagcaattca tgctgcaaac gatccttgcg ttttccttgt agcagataat caaaataaac
    38761 agttttcgtg cgctcatttt gtattttttg ctggtatttt cgataccttc gccattcttc
    38821 agtacttaat tgaccaattt gtgccaataa atcatccggc atacttttta tatcttgttg
    38881 gcagatcatt tgaatcatca tgtctacttg atagatttca ttgggcagta aaaaatgttt
    38941 ttttgctaaa agttctagca tcgccaatcc gcatgtctct ggtacgaccc tgttcttata
    39001 taaattacgc agtttttgcc aaaattttat gcttttgaaa aaagataatt ctaactgaat
    39061 ttcttttgtt aagtaagaca aaaatcctcg ccagtatgtt cttgcaggtt taacagaatg
    39121 aaatgtatac cagttcccat agtaatagcc taatcgtttt ttcatttcca gatagcctaa
    39181 ttgtaaattt aattggttcc tttggctatc aaaaagcaga aagctgccta gtgtccacaa
    39241 tgtttgacat ttccaatgga taaaaatgtc tggcatacga atttttttcg ctgggcctgg
    39301 cccttgcaca tctacgacaa atgcctctgt tgctcctttg ttaatcgcaa tatcaatagg
    39361 tattttgttg cgatacccac cgtctgcata tttatttttt ccgatctttc gataagccat
    39421 agcgggataa aatgaagcag aggcgagtat ccaatctggt atttcttctg tttttgtctg
    39481 ttggatatca gtcactactt ccgctagttc tggcagttta gtagacaccg tatataaacg
    39541 tattttggga ttatgtttga gtaaggacaa atccaaattg tctttgacca tcttttccaa
    39601 tggagcagaa gaaaccccgc cttcaattag tgctgttttc gtcatttggc gtctttctcg
    39661 atagaagcgt tcacgaaggt cttcaactgc agccatttct ggtaacgcaa gcacttgtct
    39721 tgtcgacagc tttttccata aattcacagc ttttttcata tctccttgta aaatcaatgc
    39781 gccgttcaac gcacctaccg aggtacctgt gataatctca aagttgatat catgttcctt
    39841 cagcgcctgc cacacaccaa tctgataagc accgtgcgct cctcctccac ctaaaacaag
    39901 tgctgtatga tagaccagct ttttatttaa ttgtgtggtt ccttgatagc cgtttttatg
    39961 aaaaatacgc aaccattctt ctgatagagg agattgaaat aaaaaacaac agttttcttt
    40021 aataaaaaaa cgagcgcaag cttccatata ccgaaaaaat tttttccatt caaaagtttc
    40081 accttcaatc aacagattat taaaaataac atctcctcta cttttagcaa tagtaaaata
    40141 gacggtatat tttttcgata ctgctttaaa agcacattgc ttttttgcag aacgccaaaa
    40201 agcgtctcta ctttcttgat gactttgaaa aaatggaagg ggttgttttg cttgctggat
    40261 aggcgaatac agcgacattt tctgtgaaaa gtaaactttt tttatctcca tcgcgctctc
    40321 ctttttcttc aagtatacca gtacgtcata aaaaggtcat gagtctcgta ttcgactttg
    40381 tagattccat aagaaaacaa ttcataaaac ctcctttaaa taaaaaaata caaaaatcac
    40441 aaaaattaat tgaaaatgag agtgttttca atgaaaacgt gattttgtaa tggaatttta
    40501 aaataaaaga aacaagcttt tt
//
LOCUS       DAXLPQ010000020        40425 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.020, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000020 DAXLPQ010000000
VERSION     DAXLPQ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.020"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            212..604
                     /locus_tag="ACF3UO_001293"
     CDS             212..604
                     /locus_tag="ACF3UO_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3657334.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACF3UO_001294"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACF3UO_001294"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFD3657335.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACF3UO_001295"
     CDS             2698..2943
                     /locus_tag="ACF3UO_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657336.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3164..4774
                     /locus_tag="ACF3UO_001296"
     CDS             3164..4774
                     /locus_tag="ACF3UO_001296"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFD3657337.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4751..4963)
                     /locus_tag="ACF3UO_001297"
     CDS             complement(4751..4963)
                     /locus_tag="ACF3UO_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657338.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5066..5935
                     /locus_tag="ACF3UO_001298"
     CDS             5066..5935
                     /locus_tag="ACF3UO_001298"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFD3657339.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6100..7371
                     /locus_tag="ACF3UO_001299"
     CDS             6100..7371
                     /locus_tag="ACF3UO_001299"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD3657340.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7368..8663
                     /gene="rho"
                     /locus_tag="ACF3UO_001300"
     CDS             7368..8663
                     /gene="rho"
                     /locus_tag="ACF3UO_001300"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFD3657341.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8762..9025
                     /locus_tag="ACF3UO_001301"
     CDS             8762..9025
                     /locus_tag="ACF3UO_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFD3657342.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9470..9919
                     /locus_tag="ACF3UO_001302"
     CDS             9470..9919
                     /locus_tag="ACF3UO_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3657343.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9976..11394
                     /locus_tag="ACF3UO_001303"
     CDS             9976..11394
                     /locus_tag="ACF3UO_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3657344.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11394..12254
                     /locus_tag="ACF3UO_001304"
     CDS             11394..12254
                     /locus_tag="ACF3UO_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFD3657345.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12428..13201
                     /locus_tag="ACF3UO_001305"
     CDS             12428..13201
                     /locus_tag="ACF3UO_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3657346.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13348..13713
                     /locus_tag="ACF3UO_001306"
     CDS             13348..13713
                     /locus_tag="ACF3UO_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFD3657347.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13861..15069)
                     /locus_tag="ACF3UO_001307"
     CDS             complement(13861..15069)
                     /locus_tag="ACF3UO_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3657348.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15088..15366)
                     /locus_tag="ACF3UO_001308"
     CDS             complement(15088..15366)
                     /locus_tag="ACF3UO_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657349.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15559..16215
                     /locus_tag="ACF3UO_001309"
     CDS             15559..16215
                     /locus_tag="ACF3UO_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3657350.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16657..17454)
                     /locus_tag="ACF3UO_001310"
     CDS             complement(16657..17454)
                     /locus_tag="ACF3UO_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFD3657351.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17451..18635)
                     /locus_tag="ACF3UO_001311"
     CDS             complement(17451..18635)
                     /locus_tag="ACF3UO_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFD3657352.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18660..19907)
                     /locus_tag="ACF3UO_001312"
     CDS             complement(18660..19907)
                     /locus_tag="ACF3UO_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFD3657353.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20122..21867
                     /gene="dnaX"
                     /locus_tag="ACF3UO_001313"
     CDS             20122..21867
                     /gene="dnaX"
                     /locus_tag="ACF3UO_001313"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFD3657354.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21887..22201
                     /locus_tag="ACF3UO_001314"
     CDS             21887..22201
                     /locus_tag="ACF3UO_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFD3657355.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22226..22822
                     /gene="recR"
                     /locus_tag="ACF3UO_001315"
     CDS             22226..22822
                     /gene="recR"
                     /locus_tag="ACF3UO_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFD3657356.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22886..23530
                     /gene="tmk"
                     /locus_tag="ACF3UO_001316"
     CDS             22886..23530
                     /gene="tmk"
                     /locus_tag="ACF3UO_001316"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFD3657357.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23545..23874
                     /locus_tag="ACF3UO_001317"
     CDS             23545..23874
                     /locus_tag="ACF3UO_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFD3657358.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23888..24826
                     /gene="holB"
                     /locus_tag="ACF3UO_001318"
     CDS             23888..24826
                     /gene="holB"
                     /locus_tag="ACF3UO_001318"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFD3657359.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24862..25686
                     /locus_tag="ACF3UO_001319"
     CDS             24862..25686
                     /locus_tag="ACF3UO_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFD3657360.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25679..26026
                     /locus_tag="ACF3UO_001320"
     CDS             25679..26026
                     /locus_tag="ACF3UO_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFD3657361.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26095..26967
                     /gene="rsmI"
                     /locus_tag="ACF3UO_001321"
     CDS             26095..26967
                     /gene="rsmI"
                     /locus_tag="ACF3UO_001321"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFD3657362.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27076..28197
                     /gene="dinB"
                     /locus_tag="ACF3UO_001322"
     CDS             27076..28197
                     /gene="dinB"
                     /locus_tag="ACF3UO_001322"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFD3657363.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACF3UO_001323"
     CDS             complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACF3UO_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFD3657364.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACF3UO_001324"
     CDS             complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACF3UO_001324"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFD3657365.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31683..32450
                     /locus_tag="ACF3UO_001325"
     CDS             31683..32450
                     /locus_tag="ACF3UO_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657366.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32440..34482
                     /locus_tag="ACF3UO_001326"
     CDS             32440..34482
                     /locus_tag="ACF3UO_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657367.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34763..34912
                     /locus_tag="ACF3UO_001327"
     CDS             34763..34912
                     /locus_tag="ACF3UO_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFD3657368.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34923..36437
                     /gene="dltA"
                     /locus_tag="ACF3UO_001328"
     CDS             34923..36437
                     /gene="dltA"
                     /locus_tag="ACF3UO_001328"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFD3657369.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36434..37639
                     /gene="dltB"
                     /locus_tag="ACF3UO_001329"
     CDS             36434..37639
                     /gene="dltB"
                     /locus_tag="ACF3UO_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFD3657370.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37684..37917
                     /gene="dltC"
                     /locus_tag="ACF3UO_001330"
     CDS             37684..37917
                     /gene="dltC"
                     /locus_tag="ACF3UO_001330"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFD3657371.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37920..39188
                     /gene="dltD"
                     /locus_tag="ACF3UO_001331"
     CDS             37920..39188
                     /gene="dltD"
                     /locus_tag="ACF3UO_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFD3657372.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39329..40411
                     /locus_tag="ACF3UO_001332"
     CDS             39329..40411
                     /locus_tag="ACF3UO_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFD3657373.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
BASE COUNT        13016 a         7089 c         8463 g        11857 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga atttcggctc cctattctta ttgaagaata gggagctttg tttattgtct
     3121 gagacttttc ctgcacataa attaaaaagg agtttttgaa cttatgacaa aatatatttt
     3181 tgtgaccggc ggtgtcgttt catcaatcgg aaaagggatt gttgcagctt ctttaggacg
     3241 cttattgaaa aaccgcggct taaaagtaac tatccaaaaa tttgatccat acatcaacgt
     3301 ggatccgggg acgatgagcc catatcagca cggagaagta ttcgtaacag atgatggtgc
     3361 tgaaacagat ttggatctgg gccactacga acgttttatt gacatcaatt tgaacaaata
     3421 ctccaacgtg acgacaggaa aaatctattc tgaagttttg cgtaaagaac gtaagggcga
     3481 atacttggga gcaactgttc aagttattcc tcatattaca aatgagatca aagaaaaaat
     3541 catgcgagca gctaaaatga ctgattcaga tgtgatcatt acagaagtag ggggaacagt
     3601 aggggatata gaatctttgc cattccttga agcacttcgt caaatgaaag cagatgtcgg
     3661 tacagataat gttatgtata tccatacaac attgattcct tacttgaaag ctgctggaga
     3721 aatgaaaact aaaccaacgc agcacagtgt aaaagagcta cgtggtttag gtatccaacc
     3781 gaatattttg gtggtacgta cagagcaacc tgtttctcaa agcgtgaaaa acaaattggc
     3841 acaattttgt gatgtcgaac cagaagcagt tatcgagtcg ccagatgtag atacacttta
     3901 ctccatccca ttagttttac aagcacaagg aatggatcaa attgtttgcg accatttaaa
     3961 actagataca ccagaagcag acatgacaga atggaaagaa ttagaagaac gtgtcttgaa
     4021 cttgaagaaa aaagtacgga ttgcgcttgt cggtaaatat gtcgagttac cagatgcata
     4081 tatctcagta gttgaagcat tgaaacattc tggtttcgcc tataattcag acatcgagat
     4141 cgattggatc aaagcacaag aattaacgag agaaaatgta gaagaacgtt tgaaagacgc
     4201 agatggaatc ttggttcctg gtggatttgg tgatcgcgga gtagaaggga aaatcgaagc
     4261 gattcgttat gctcgcgaaa atgacgttcc gtttttaggt atttgtcttg gtatgcagat
     4321 ggcttgtgtc gaatttgcac gtaacgtcgt tggattagaa gatgcgtcat cagctgaaac
     4381 gaatccagat acagcaaaca atattattga tttaatggct gatcaggaaa acatcgagaa
     4441 tttgggtgga actttacgcc ttggattata cccatgtaaa atcaaaaaag gaacgaagac
     4501 ggctgaagca tatgatggag ccgatgttgt gcaagaacgt caccgtcacc gctatgagtt
     4561 caataacaaa tatcgtcaat tgtttgaaga acaagggcta gtcttttcag gtgtctcacc
     4621 agataaccgt ttagtagaaa tcgtagagct gccagagaaa aaattctttg tgggatgcca
     4681 attccaccca gaattgattt ctcgtccaaa tcgcccgcaa aaattaatca aagcatttgt
     4741 cggagcatca ttagcagatc acgaaacaaa ataatttttg aacttgatag aaagagaaaa
     4801 gtagcaagag aaggggataa gcaattttct tgtcactttt ctctttttct gatttgttat
     4861 tatttgtagg aaaaaagata gaaagcaaaa gacttttttc gattaaagcg ctattggata
     4921 ttttattttt tgcaaaaaac ttcttgaaaa ttttcatttt cattgatttt agtagaaaac
     4981 taccgaaatg tttggtaaaa tagggtcgtt ggttaagaat tgtcttaaca aatttagttt
     5041 tacaaaactt aggaggaatt ttattatgcc agtagtatca ggagctgaat ttttaaaagc
     5101 tgctcgtaaa ggcggttacg ctgtcggcgg attcaacaca aacaacttgg aatggactca
     5161 agcaatcctt gaagcggctg aagcaaaaca agcaccagta cttatccaaa catcaatggg
     5221 tgcagctaaa tacatgggtg gttacaaaat ctgtaaagat ttaatcactg atttagttga
     5281 agcaatgaac atcactgttc cagttgctat ccacttagac catggtgatt acgaagctgc
     5341 tttggaatgt atcgaattag gctatacttc agtaatgttc gatggttcac atctaccatt
     5401 tgaagaaaac ttgaaattag ctaaagacgt tgttgaaaaa gcacatgcaa aaggtatctc
     5461 agttgaatgt gaagttggtt caatcggcgg agaagaagac ggaatcatcg gtaacggcga
     5521 attagctgat attgaagaat gcaaacaaat ggttgctaca ggtatcgact acttagcttg
     5581 cggtatcggt aacatccatg gtcaatatcc agaaaactgg aaaggattag cttttgacca
     5641 cttacaagca attgctgatg ctgtaggtcc agacatgcct ttagtattac atggcggatc
     5701 aggtattcct caagatcaaa tcgaaaaagc tatctcaatg ggtatctcaa aagtaaatgt
     5761 taacactgaa ttccaattat catttgctgc agctactcgt aaatatatcg aagctggtaa
     5821 agataaagaa ggtaaaggat tcgaccctcg taaattatta gctccaggta aagcagcaat
     5881 cgttgaagat gctaaatctc atatcgactg gttcggttca gctaacaaag cgtaagcatc
     5941 cacataacag atacgatata taggaatgga gaacgacttt tgaagtcgct ctccattctt
     6001 ttttacttaa aacggcagac catgctcgtt tctttttttt atctatgata aaatacaagc
     6061 atatccatga aaaaagatta ataaacaagg tggaaacaga tgaaaaaaat cgtaatcaaa
     6121 ggaaaccgac ctttagctgg tgaagtaacg atcagcggtg caaaaaatag tgcagtcgca
     6181 ttgattccag ctgcaatctt agctgattcc ccagtgatct tggaaggtgt gccggacata
     6241 caagatgttc attcattaat tgaaatttta gagatcatgg gcgcaactgt ccatttttcc
     6301 aacaacatac tagaaatcga tcctcgagaa gtcgtatcga ttccgatgcc gcacggaaaa
     6361 atcaatagtt tgcgtgcttc ttattatttt atgggaacac tgcttggtaa atttggcgaa
     6421 gcggtagtag gcctgccagg tggctgttat ttaggcccta gaccgattga cctacacgtc
     6481 aaaggatttg aagctctagg tgctgaagtg acaaatgaac atggtgccat gtatttacgg
     6541 acagaaaata aaggattgcg tggcaatcgg attttcatgg acgtggtttc agtcggagca
     6601 acgatcaatg tgatgttagc tgctgtaaaa gcaaaaggac agacagtaat tgaaaacgct
     6661 gcacgagaac cggaaatcat agatgtggca actttactga ataatatggg ggcaaaagtt
     6721 cgaggagcgg gtacagatgt gatccgtatc gaaggagtcg aaacattaca tggctgtcgg
     6781 catttcatga ttcctgaccg catcgaagca ggaacctatc tagcattagc agctgcagta
     6841 ggaaatggta tcaaagtgaa aaatgtgatc tttgaacatt tggaaagctt tatagcaaaa
     6901 ttgcaggaaa ttggtgtcca tatgaaaatc agcgaagatg aaatcgaagt ttacccctcg
     6961 aaagaattaa aacccgcaaa catcatgacc tatccttatc caggatttgc cacagatctg
     7021 cagcagccac ttactgcgtt actattgatg actacaggca cttcagaaat catcgatacg
     7081 atctatgcga aacgtgtgaa ccatgtgccg gaactagcac gaatgggcgc tgatattacc
     7141 gtggaaggaa atatgatcat cgtgaatggt ccaaataaac ttcacggcac agaagtcgtg
     7201 gcttctgatc ttcgggcagg tgcttgttta gtgattgctg gactattggc agaagggaca
     7261 acgacgattt acaatgtaga ttatatctta cgcggttatg atcatattat cgagaaacta
     7321 acagccttag gggcatcaat tgaaatgata gaggaagtgg gagctgaatg agcgattatt
     7381 tgacaatggc agaactagag aacaaaacgt taaaagaagt ttatagttat gccaaagaat
     7441 ttaaaattcc ttattacagt aagatgaata aaaaggaatt atctctagct gtgattcgtg
     7501 cacaagcaga gaaacaagga ttttattata tggaaggaat attggatatc gttggtcaag
     7561 atggttacgg ttttttacgg ccaatcaatt atggaccaag tgcagaagat atctatattt
     7621 ctgcctcaca aatcagacga ttcagtttga gaaatgggga caaagtggca ggaaaagccc
     7681 gtccacctaa agaatcggaa cgttattatg gtttgatgca cgtggaaagc gttaatggaa
     7741 aagatccgga agaagcaaaa gaacgtccgc attttccagc cttaacacct ctttatccgc
     7801 aaagacagct tcaactggaa acaacaccgc aaagactatc tacccgaatg atcgatatct
     7861 tttctccaat cggttttggt cagcgtggat tgatcgtcgc accgccaaaa gcagggaaaa
     7921 cttctgtatt aaaagaaatc gcaaatggta tcaccgaaaa ctatccggaa gtagaattaa
     7981 tcgttctact gattgatgaa cgaccggaag aagtaacgga tctagaacga agcgtgaaag
     8041 gcgacgtggt atcttctaca tttgatctgc agccgcaaaa ccatactcga gtttctgaat
     8101 tagtattgga acgcgcaatg cgtttagtcg aagataaacg agatgtcgtt atcttgatgg
     8161 atagtattac tagacttgct cgggcctata acttagtcgt tccaccaagc ggacgtacat
     8221 tgagtggcgg gattgaccca gccgcattgt ataaacctaa gaaatttttc ggggcagcaa
     8281 gaaacatcga agaaggtggc agtttgacga ttttagcgac cgctttagtc gatacaggaa
     8341 gccgtatgga tgacgtgatc tatgaagaat tcaaaggaac tggaaatcta gaattacaac
     8401 tttcacgtga attatctgaa cgtcggatct tcccagccat cgatatcaaa aaatcaggta
     8461 cccgaaaaga agaattattg atgccaagtg aagaattaga agaaatttgg aaacttcgaa
     8521 aaaatatgac tggagattca ttagaatata cggaacaact gatccgcttt ttgcgtaaaa
     8581 caaaaaacaa tcagcaattt ttcaaagaat ttcaagatgt ctcctttggt aaaaaaaatc
     8641 cgaccagaaa tctgaaaaga taattgcaac cttgactgaa acatgttaag atgttaatgt
     8701 tgtaaatcga caaatcaact ctggttcagc aaatggagca gggcaaagga gcgaaaaaat
     8761 catgaaagaa aacatccatc cagattacca cccagtagta ttcatggatt caacaactgg
     8821 tttcaaattc ttgtcaggtt caacaaaaac ttcacaagaa acagttgaat gggaagacgg
     8881 taatacatac ccagtcatcc gtgtcgaagt aacttctgac tcacatccat tctacactgg
     8941 acgtcaaaaa ttcacacaag cagacggacg tgtggaccgt ttcaacaaaa aatacggtct
     9001 caaagacgca aacgctgcgg aataataaaa acgctgataa ctcaacgttt agcagactat
     9061 ctgataggga tagtctgttt ttttatgttt tttgccaatt taaaacttcg tttgatgctg
     9121 aaaaagtcgt aggatcataa tgcacaaaac aatgaaaaac tagtatatag ttttaattat
     9181 ccacttgata aaaacacctt atattaacga aatgaagagg ggttatttcg aagtaaaaaa
     9241 ccatttacct aaaattagaa gctaagcttt cctttcaagg aaggcttttt gttttgttat
     9301 agacttgcga ttgtttgtga gctagatcgt tcattttaat gacttataca cgcggatgat
     9361 gggtcttttt cctctgttca ttcataatat tgaacggtac agctagcgat gctatactga
     9421 cctcagttcc aagaaaacgt taacattttt tgtgggggag aggtttttta tgaggtttga
     9481 tcaattgatc gcagaagaac tgattgtttt cgatccatcg atagattcaa aaggatcatt
     9541 atttgagcga ataggggatg tgttgaaaaa aacaaataag gtaagaaatg ttcaaaaagt
     9601 cgttaaggca ctattcaaac gagaggagga gatctccaca ggaatagaag atggatttgg
     9661 gattccccat gcaaaaagca aatatgtgac aaaaccagca ctgtgttttt ttcatacagc
     9721 caaattaacg gactatagcg ggatagatga aatgccaatt gaatatattt ttgccatcgt
     9781 agttcctgaa aaatcagcag atatgcatct agagattctc agcacactct ccagacgatt
     9841 gatgaatgca gattttagaa agggaataaa agaagccact acgccagcag atatcatcag
     9901 acagattagt caagaatgaa aatagtagag tctttgtccg agtatcgata gtgaagaaaa
     9961 aggaggaaaa taatcatgaa aatcgttggt gtaactgctt gcccgactgg aattgctcat
    10021 acttatatgt cggcagaaaa attagaagta acagcaagaa atctaaacca tcaagcaaaa
    10081 ttcgaaacac aaggtgtaaa aacagaaaat cagttatctg aacaagaaat caaagaggca
    10141 gatgcaatca ttcttgcagt agataaagaa atcgaattgg accgatttgc cgggaaaaaa
    10201 gtaaagcgtg tctctacaag ccgagcaatc aaagaaccgc aagtagtaat agacgaagca
    10261 ttgagagata ttggcgtatt cgttgtgtct aatgaaaaag aaccagctgc aaatgagaaa
    10321 aagccgacaa tctataatca tttcatgaat ggtgtgaatt acatgcttcc atttgtgatc
    10381 gcaggcggaa tcatcatcgc actgagtttt gcctttggga ttacagcggc tgatcccaac
    10441 tcagcagact ataatgtgtt agcagctgca ttttcaagga tcggaggaga tacagcgttt
    10501 gccatgatgg ttcctgcgtt aggcgcgggg attgctacat cgattgctgg aaaagcaggt
    10561 tttgccccag gaattgttgc cggattactg gcctctacag gtggttcagg ttttcttggc
    10621 ggaatgattg gtggcgtgct agcagggtat atctgtgatt ttctggcaaa taaaattagc
    10681 gtaaaaaaag aattttctgc tatttatcag ctgattgtcg tccccttttt atcgatctta
    10741 attattgggc ttttgatggt atttgtgatt gaacaaccga tcacatgggt gttggatgct
    10801 ttgacaaatt ggctgaatag cttgggaaat acatccgggc tattgttcgg attacttatc
    10861 gggatcatga tggcagctga tatgggtggg ccgatcaata aatcgacttc gactttctcg
    10921 atcggtttga tgtcagctgg agtaaatgca ccgattgctg cttgtatggc tgcaggaatg
    10981 acacctcccc taggtattgc tttagccact ttattattca aacataaatt taccaaagaa
    11041 gaacggactt caggtcaatc atgctggatt ttaggcgctt cgtatattac agaaggtgct
    11101 ataccgtttg cggtatctga cccgatccgc gtgataccta gtttgatgac aggttcagca
    11161 gtcgctgcag ggatttccat ggcagtagga gttacttcaa tggcacctca tggagggatt
    11221 tgggtgatgc taattccaaa tgttatgaac aatttaccta tgtatgtctt ggcaattgca
    11281 tcaggtacag tcactacagc ctttatgctt ggactattga aaaaaacagt gaaagagaaa
    11341 aaacaagaca agtggacgaa aaatgaaaat ctaacaaatg aggtggaagc gtaatgttat
    11401 atacaatgaa agagttattg aaagtggcta aagagaatca atttgcagta ccagccttca
    11461 atatttgcag ctatgatatg atgaaagcaa tcatcgaaga agcagagaga ttagaagcac
    11521 cagtaatctt agaaattcat cctgatgaaa tcgcctattt aagtgatgag tttgttgcgg
    11581 cagtaagagc ctatgcttat acaagtaaac tgccgatcgt tatccacttg gatcatggcg
    11641 gtacgataga agatgtctta cgggcgattc gaaacggcta ttcttccgtg atgatcgatg
    11701 cgtctttgaa atcattcgac gacaatgtac agattacgaa aaaagtggtt gcgttagctc
    11761 atgcggtaaa tgtctcagtg gaggctgagc ttggaacgat tgggaataat ggttctgctg
    11821 aaggaggtgc tgaaacaatc atttatacag atcctgatca agcgaagatt tttgtgaaag
    11881 aaacaggaat cgatacactt gctgtagcaa ttggaacagc gcatggcttg tatccgaaaa
    11941 acagaactcc aaaattaaat atcgacttac tgaaagaatt gaaccaacaa atcgatcttc
    12001 catttgtttt acatggcggt tcaggtaatc cggacgcaga agtcagcgaa gcagtaaaat
    12061 acggagttgc caaagtgaat ttgagctcag atcttaaaag cgtctttttc aatgctttga
    12121 gagaaatatt gagtgaaaat ccatcgatgt acgagccgaa tgcaatttat ccagcagcta
    12181 ataaaaaggt acaagaagtg gtcaaacata aaatggaaat tttgaacaca gtaggcaagg
    12241 ctagtttata ctaaaaataa aaatgtgtgg tcaagagggt atgacaatag tcttgtcata
    12301 ccctcttaac cacacacgat gttcagaagt agttttttcg aaaaatttct tcttatttct
    12361 cgaagccaat cacttctgtc acaacctctt ttttcctgtt actatataaa gtaaatgggg
    12421 tgattttatg ttgaatgaag tggagaatag acagcaggag attgtgaatt atctaaaaaa
    12481 caaccaattt gcaagagtca ccgatttgat cgagttagta aattatagcg aagccacgat
    12541 taaacgtgac cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc
    12601 catgcttatt gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga
    12661 agaagaaaca gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat
    12721 ggtcttattc ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt
    12781 tgatggtttg cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac
    12841 aacggcaaaa gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg
    12901 ttcaaaagcc tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg
    12961 cgggctagat ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa
    13021 agcttttaga aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca
    13081 taaattcatg catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga
    13141 actgacaaaa gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata
    13201 aattattacg tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct
    13261 cgcttctctc agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt
    13321 tttatccagg agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca
    13381 atcatgatct gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg
    13441 gattcaacga ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg
    13501 atcttacgta aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt
    13561 atcttgtggc tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg
    13621 attcctgctc tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa
    13681 ggcatcgtac cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat
    13741 aaatgaaagc tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac
    13801 tcaaaaaacc gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga
    13861 tcaaatttca tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg
    13921 gccattaaca agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa
    13981 tcctctaaat gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc
    14041 taggtctaaa ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat
    14101 ttttaaacaa acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc
    14161 tccagagata agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt
    14221 taagaataaa tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc
    14281 agtcaatgga cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc
    14341 agcaactaag tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga
    14401 aagacccatc aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt
    14461 gatattccat gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg
    14521 aaagacaagg caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa
    14581 acgaaaatca gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa
    14641 actagtactt aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc
    14701 agtaacgata gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg
    14761 aactaaatac aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata
    14821 gaagatcgcg ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat
    14881 gaataagcgt gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct
    14941 caagctggcg tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata
    15001 aatcaggtag acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt
    15061 cttttccatg tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg
    15121 aacttctaca tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc
    15181 tcttgtagac ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac
    15241 tgctttgatc aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt
    15301 catatcaaat cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta
    15361 attcatgttt tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa
    15421 aaaggaaaaa aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag
    15481 taaaatacct ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt
    15541 ttggatgggg gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat
    15601 tttccgatta tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc
    15661 catacgtata tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga
    15721 gaatttaacc ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat
    15781 tcacaattca tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat
    15841 cgaatcaatc gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat
    15901 gtaaaagagt attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta
    15961 ttaaacggaa agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt
    16021 gtgcggacag aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa
    16081 ttttgtggca tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat
    16141 ggtattatca ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac
    16201 aatattatct tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga
    16261 gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    16321 agctgattga acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    16381 ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga
    16441 gttggtagga gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat
    16501 aagaagagcc aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta
    16561 gatgtaagct tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc
    16621 acagcccttt ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc
    16681 aaaagtcccg ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg
    16741 gcttttgggg attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt
    16801 taatttgata ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata
    16861 acgcgaaaca gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat
    16921 gatgatttct actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac
    16981 acgataatgt cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc
    17041 ttttgcagca ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga
    17101 atcgattctg ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc
    17161 acgctgtccc atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct
    17221 taagtaatta tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa
    17281 gactcgtcct ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg
    17341 atctgttgtg aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac
    17401 cggccagcca acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag
    17461 taacctccga tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc
    17521 aattttttct ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg
    17581 tagtagtaga cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt
    17641 aatacgtaat tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt
    17701 gtatatccat ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga
    17761 atctgtgatt tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa
    17821 tactggcttt taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc
    17881 ttttgttgcg tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct
    17941 gctcttgaaa cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg
    18001 cggataactg taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa
    18061 gggaaataca cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca
    18121 aaccattttt tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca
    18181 aaaggaagta ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga
    18241 ttatggcagt agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca
    18301 cagttgggac aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta
    18361 tctgaaaaac cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc
    18421 tgttcttggg ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg
    18481 ccagccatac gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag
    18541 atattcaggc agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg
    18601 ccgcaattag gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat
    18661 taattaacgg ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg
    18721 ttggaaagat ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg
    18781 ttttctacag gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg
    18841 caaactggac atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct
    18901 gcttgttgtt tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt
    18961 gcattcattc ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg
    19021 gctgcttcca taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca
    19081 cctagcatcg ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa
    19141 atgctggcta cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc
    19201 aatgcagtat ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt
    19261 tgaccatctg cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa
    19321 tactgctcat tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta
    19381 taaaataaaa tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat
    19441 tctgcgttat agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc
    19501 tttatttctt ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat
    19561 ttgaatcggt caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga
    19621 gctgcgtcat ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca
    19681 ccatcgacca aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa
    19741 acatcttctg ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct
    19801 tttgtcatga ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct
    19861 gccagaccgc cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc
    19921 tctgattcag ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa
    19981 acttctcgga ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa
    20041 aagccgagaa ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt
    20101 ttttaaaaaa gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag
    20161 cgtttcgaag acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt
    20221 tcccacaaaa cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt
    20281 gcagcaaaga ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc
    20341 aacgaatgcg aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc
    20401 gatgctgcca gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat
    20461 gcgcctacaa aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca
    20521 ggagctttca atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc
    20581 ttagcaacga ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt
    20641 gattttaaac ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa
    20701 tcgactatca gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg
    20761 atgcgggatg cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact
    20821 ttagatgatg ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg
    20881 agtgcttgcg tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca
    20941 gccggcaaag aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg
    21001 atgtatcagc aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt
    21061 acagaattgg cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc
    21121 gatactcaaa atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca
    21181 gtcaaacttg cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat
    21241 gatcagatag taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa
    21301 ctacgcagta atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat
    21361 aaaaaacaga caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa
    21421 gcgacaagac agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta
    21481 tctgtcactc agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga
    21541 ctagtgattg cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg
    21601 cagctttcgg tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt
    21661 tatattacaa gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa
    21721 gagggaacag aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct
    21781 caagaacaag aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc
    21841 gaagctgtta cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat
    21901 gggcaatatg caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc
    21961 acaagagctg ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc
    22021 ggtttttaca ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc
    22081 tgatgatatc gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca
    22141 aattgatgtg gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta
    22201 gttttaaact gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga
    22261 cagctacatg aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac
    22321 gatcgatatg aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg
    22381 cgatttgcat ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg
    22441 tagaaatcct tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat
    22501 ggcaatggaa aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc
    22561 accgatggaa gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca
    22621 tgatgcagat gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac
    22681 agctatgtat ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca
    22741 tggtctgtct gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt
    22801 cgaaggaaga cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag
    22861 cagcacaaga gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga
    22921 tggtgcagga aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa
    22981 aacagaaatc attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc
    23041 agtgatcctt gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc
    23101 agcagcaaga agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat
    23161 cgttttatgc gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat
    23221 cggcgttacc gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt
    23281 taccctttat cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca
    23341 aaatcaaatc gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc
    23401 ttacttaaag ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag
    23461 ctttgaagaa gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt
    23521 tgaaaactag gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac
    23581 agcaaccgtt tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg
    23641 acaggcggct tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt
    23701 gtagaagaag cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct
    23761 acacctgtta cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa
    23821 gtaggcggtg ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag
    23881 ctgagctatg aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct
    23941 tcaacggagt tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg
    24001 aacaggaaaa catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa
    24061 agacaatctg ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc
    24121 agatgttttg gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt
    24181 gcagacggaa ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga
    24241 agctgaaaaa atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc
    24301 tggagatttt ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca
    24361 atctcgttgt caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt
    24421 gcaagaagag cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt
    24481 aggaaaagca gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta
    24541 tcaatggttc gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa
    24601 attggtaaaa tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt
    24661 ttattatcag gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca
    24721 gataaaccag ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag
    24781 ttttcaggct gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga
    24841 tgatgatcaa ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt
    24901 catatctatt attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc
    24961 gaatctcagc aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc
    25021 aatgaccttc ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa
    25081 aaagacaaaa aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg
    25141 cagttgcgtg agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa
    25201 ttgatttttt ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg
    25261 gccgctgtat ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag
    25321 ataataggcg gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat
    25381 ttcgtgcctg tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa
    25441 atttccggtt tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag
    25501 acagcgaaaa aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg
    25561 aaagtcgtag ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa
    25621 aatcctgtcg aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat
    25681 ggataagaga tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt
    25741 aacagaactt gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt
    25801 ggagatggaa aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc
    25861 tccagctgaa aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta
    25921 tgaagaagga ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc
    25981 ttgtgcgttt tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg
    26041 agactggagc ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat
    26101 aatcaaaaaa gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca
    26161 attggaaatt tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt
    26221 atcgcaagtg aggatacgcg taatacacaa aagttattga atcattttga aatccataca
    26281 ccccaaaaaa gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg
    26341 ttaaaagaag gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat
    26401 cctggacatg agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca
    26461 ggacctacag ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta
    26521 ttttatggct tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa
    26581 gaacagacag ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg
    26641 aatttcttag aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc
    26701 catgaagaat accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca
    26761 gtaaagggtg aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa
    26821 gttgatgaag agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa
    26881 aaaccaaatg ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc
    26941 taccgtcagt accatgaatt agactgagat agtataagtt gtctataatg aaagactaat
    27001 gaggaaatca gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat
    27061 gaataagagg tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa
    27121 atcattcata ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag
    27181 tttcgcggac atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta
    27241 gtgactacag caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa
    27301 aaagcgtatg agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc
    27361 gatatttcca aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt
    27421 agtatcgatg aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc
    27481 aaaatcgccc gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg
    27541 ggagtaagtt acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga
    27601 atcacggtag ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa
    27661 tttcatgggg tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga
    27721 aaagacctat atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat
    27781 tctctttatc gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga
    27841 aaatctgtgg gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg
    27901 actcagttgc gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat
    27961 gggaaaacag tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg
    28021 acattgccag aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg
    28081 gaggaaatct tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg
    28141 gacccgatga cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa
    28201 cagctttgag agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag
    28261 tcttgctttt tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca
    28321 acttgattgg attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga
    28381 aattgtagtt ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt
    28441 tgcgaaagga gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct
    28501 gtccatgacc agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc
    28561 agacaaacat ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa
    28621 tcgttgcgca agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat
    28681 cggaaatttt gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg
    28741 taaagactgt tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata
    28801 tagttttggc tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa
    28861 cttctttcat ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata
    28921 aataagaaca aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag
    28981 ggcgttcaaa gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc
    29041 ttattctgaa taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga
    29101 aaaatatgag gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt
    29161 cacaacctca tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca
    29221 tcggacgagc ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt
    29281 ttggatcatg atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac
    29341 cttcgaaacc acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt
    29401 tgtcatatgc aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt
    29461 attcacagta gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca
    29521 atttttcaaa tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt
    29581 ctttatctgt gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt
    29641 cagttagact ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc
    29701 atgcatctgc attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg
    29761 ggtttgtttc ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc
    29821 ctaacgatac agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa
    29881 gacgtttccc gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt
    29941 tacaacgttc tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta
    30001 actgccagaa tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg
    30061 taacaacacc taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc
    30121 cttgcaagaa tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt
    30181 tatcgtaatt cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt
    30241 tgatgtcgta attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca
    30301 gtttagggaa gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa
    30361 ttgctttttg aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga
    30421 aaggagtttg tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag
    30481 catcgaagat atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat
    30541 cgatccattc ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa
    30601 gcaattcatc tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa
    30661 taatctgtga gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat
    30721 tgccgatttt gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca
    30781 tcggtgtata aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat
    30841 ttgctatatg tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca
    30901 gatctcgctg tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt
    30961 ggtccttgtt gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa
    31021 aatctcgttt ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta
    31081 gtaatatatg ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc
    31141 ttttgatttc ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg
    31201 ataatgagcc gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat
    31261 cgaaatcaac atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct
    31321 gagtaacgac agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg
    31381 ttcttgtcta tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt
    31441 attcaatgtg ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa
    31501 aaaggtgaaa acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa
    31561 ataattgaat aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat
    31621 tattcgtaga tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag
    31681 aattggaaaa gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc
    31741 ccgtcaaagc cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta
    31801 tgggcccaag tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc
    31861 ctacgatggg cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc
    31921 tcagtgactt tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata
    31981 ccctaaatgc aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg
    32041 aaatggaaaa gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac
    32101 ggtatcccga tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg
    32161 ttgttcagcc acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg
    32221 ctacagaatt gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt
    32281 tagtcaccca tgatccatat acagcaagct actgcgatag aattttattt attaaagatg
    32341 gtgtgatttt ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa
    32401 tagacatgca ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt
    32461 aaaagttttt ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc
    32521 gtaatgatct attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca
    32581 agtcaagata cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt
    32641 ttgctttttt tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata
    32701 ggcatctatc agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa
    32761 atcatgataa ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc
    32821 aaactctttt caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt
    32881 atctccattc catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta
    32941 tctgtatatt caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa
    33001 gaacaagcag atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc
    33061 gggttactac ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca
    33121 tggatgatca gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt
    33181 ttcgtttgtg tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc
    33241 atattgagta aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg
    33301 caagttcatt tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt
    33361 tctttaatga caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa
    33421 gtttcctccc cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt
    33481 ctagcagagg aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg
    33541 agtatctata gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa
    33601 acacaatatc aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca
    33661 cctggtcata ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat
    33721 ggatctagta ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt
    33781 gtattaggtg acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt
    33841 tttgaaaaag caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat
    33901 aatgaaaaaa tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt
    33961 tattattctt atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt
    34021 ccggatgacc aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct
    34081 tccagctatt cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca
    34141 ctatttgtcg ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta
    34201 gcagaagcag aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa
    34261 agaaggatca gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata
    34321 ttagggatca ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc
    34381 gattactggt tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat
    34441 gtcattacga gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag
    34501 ataataaata gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat
    34561 ttttgtcaca acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa
    34621 aagcagtgat ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa
    34681 acggtttctg taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga
    34741 ggttatatga ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg
    34801 gggaaaattc atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct
    34861 gtatcactat aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga
    34921 gtatggaaat caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc
    34981 gagttgctta tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg
    35041 cacttgctta ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca
    35101 atttggagtt tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt
    35161 tgccgattga agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac
    35221 catctatggt catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa
    35281 caaaaaaaga atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg
    35341 taaaaggtac agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag
    35401 gcgtacaaat cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg
    35461 ggatcaagcc tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat
    35521 tttctattta tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg
    35581 ttcaagactt tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt
    35641 ctactccatc atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc
    35701 cggaattgga catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc
    35761 tacttgatcg attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg
    35821 tagctatttc aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga
    35881 ttggctacgt aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa
    35941 aaggagaaac gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca
    36001 atcccgaaaa gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag
    36061 gggatgcagg tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc
    36121 aggtcaaatt acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag
    36181 acaaccgaat caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc
    36241 tggttgcttt tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat
    36301 ctatcaaaga acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt
    36361 atgtcgatct gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg
    36421 aggtgaatcc tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt
    36481 tcttttagcc attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt
    36541 accagtttat caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta
    36601 ttggcaacag ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg
    36661 ctattttgtt tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt
    36721 agcgataatt ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc
    36781 gttacttggt tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga
    36841 aataagagat ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt
    36901 ctttccaaca atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct
    36961 ccatccgcct gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt
    37021 tgtcggtttt ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt
    37081 agtgggacgc attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta
    37141 cgtgtacagt atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac
    37201 aagctacatg atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa
    37261 tatcaaagaa ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt
    37321 atatatgcga ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat
    37381 gtcaaatatc ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg
    37441 gtactacatc gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat
    37501 ccgatttaag aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc
    37561 cgtatttttg acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga
    37621 taaacttttt tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg
    37681 aaaatggaag aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga
    37741 aaaaatcgtg atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa
    37801 ttattagtcg agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga
    37861 gaggattgga gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta
    37921 tgaaaaagaa actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg
    37981 tgttttttac ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct
    38041 cttcttccat gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg
    38101 aaaaacaata tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc
    38161 cgtctgttct ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg
    38221 ggacacaatc gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca
    38281 agaaagtcgt ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt
    38341 actttaatac gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag
    38401 taacgcctgc tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga
    38461 atgatacgtt gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat
    38521 ctttgaatca gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca
    38581 atattgggtt gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac
    38641 aataccaaga aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga
    38701 ataatccatt cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag
    38761 agctcaaaca gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc
    38821 agctggtctt ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg
    38881 ttaacgagaa atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca
    38941 aaaagatcaa atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc
    39001 aagcgggtac caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg
    39061 ctgcagatca acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc
    39121 atcttgacga tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat
    39181 taaaataaag aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga
    39241 ataaaagata aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca
    39301 atatgaatat agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga
    39361 tttaacttct gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga
    39421 atatgccaaa ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa
    39481 acatggtgct ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt
    39541 tatggtaaca aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg
    39601 ggggcaagtc atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca
    39661 cggtgtgatt ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta
    39721 tgaaataaag gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg
    39781 gggcatacgt cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag
    39841 taaatattta ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt
    39901 attagagaat ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca
    39961 agaagaagta ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc
    40021 ttttgcttta gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga
    40081 ttcgatttta ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa
    40141 aaaattattg aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac
    40201 agtgatttct ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc
    40261 gtctgtagcc attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga
    40321 agatgattat ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga
    40381 aacagttgaa aaaattcgga gttatgaata atgaataata gaata
//
LOCUS       DAXLPQ010000021        38858 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.021, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000021 DAXLPQ010000000
VERSION     DAXLPQ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.021"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(31..588)
                     /gene="frr"
                     /locus_tag="ACF3UO_001333"
     CDS             complement(31..588)
                     /gene="frr"
                     /locus_tag="ACF3UO_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFD3657374.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(591..1313)
                     /gene="pyrH"
                     /locus_tag="ACF3UO_001334"
     CDS             complement(591..1313)
                     /gene="pyrH"
                     /locus_tag="ACF3UO_001334"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFD3657375.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1449..2330)
                     /gene="tsf"
                     /locus_tag="ACF3UO_001335"
     CDS             complement(1449..2330)
                     /gene="tsf"
                     /locus_tag="ACF3UO_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFD3657376.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2429..3211)
                     /gene="rpsB"
                     /locus_tag="ACF3UO_001336"
     CDS             complement(2429..3211)
                     /gene="rpsB"
                     /locus_tag="ACF3UO_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFD3657377.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3570..4049
                     /locus_tag="ACF3UO_001337"
     CDS             3570..4049
                     /locus_tag="ACF3UO_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3657378.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4266..5357
                     /gene="phnW"
                     /locus_tag="ACF3UO_001338"
     CDS             4266..5357
                     /gene="phnW"
                     /locus_tag="ACF3UO_001338"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFD3657379.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKELLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5350..5478
                     /locus_tag="ACF3UO_001339"
     CDS             5350..5478
                     /locus_tag="ACF3UO_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFD3657380.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5482..6027
                     /locus_tag="ACF3UO_001340"
     CDS             5482..6027
                     /locus_tag="ACF3UO_001340"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFD3657381.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6481..8172)
                     /gene="argS"
                     /locus_tag="ACF3UO_001341"
     CDS             complement(6481..8172)
                     /gene="argS"
                     /locus_tag="ACF3UO_001341"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFD3657382.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8592..9539)
                     /gene="arcC"
                     /locus_tag="ACF3UO_001342"
     CDS             complement(8592..9539)
                     /gene="arcC"
                     /locus_tag="ACF3UO_001342"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFD3657383.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9654..10673)
                     /gene="argF"
                     /locus_tag="ACF3UO_001343"
     CDS             complement(9654..10673)
                     /gene="argF"
                     /locus_tag="ACF3UO_001343"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFD3657384.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10764..11993)
                     /gene="arcA"
                     /locus_tag="ACF3UO_001344"
     CDS             complement(10764..11993)
                     /gene="arcA"
                     /locus_tag="ACF3UO_001344"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFD3657385.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12454..13155
                     /locus_tag="ACF3UO_001345"
     CDS             12454..13155
                     /locus_tag="ACF3UO_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3657386.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(13764..14780)
                     /gene="tsaD"
                     /locus_tag="ACF3UO_001346"
     CDS             complement(13764..14780)
                     /gene="tsaD"
                     /locus_tag="ACF3UO_001346"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFD3657387.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(14777..15241)
                     /gene="rimI"
                     /locus_tag="ACF3UO_001347"
     CDS             complement(14777..15241)
                     /gene="rimI"
                     /locus_tag="ACF3UO_001347"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFD3657388.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(15248..15790)
                     /gene="rimI"
                     /locus_tag="ACF3UO_001348"
     CDS             complement(15248..15790)
                     /gene="rimI"
                     /locus_tag="ACF3UO_001348"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFD3657389.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(15774..16496)
                     /gene="tsaB"
                     /locus_tag="ACF3UO_001349"
     CDS             complement(15774..16496)
                     /gene="tsaB"
                     /locus_tag="ACF3UO_001349"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFD3657390.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(16687..17667)
                     /locus_tag="ACF3UO_001350"
     CDS             complement(16687..17667)
                     /locus_tag="ACF3UO_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657391.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(17691..19175)
                     /gene="galT"
                     /locus_tag="ACF3UO_001351"
     CDS             complement(17691..19175)
                     /gene="galT"
                     /locus_tag="ACF3UO_001351"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFD3657392.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(19187..20176)
                     /gene="galE"
                     /locus_tag="ACF3UO_001352"
     CDS             complement(19187..20176)
                     /gene="galE"
                     /locus_tag="ACF3UO_001352"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFD3657393.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20424..20591
                     /locus_tag="ACF3UO_001353"
     CDS             20424..20591
                     /locus_tag="ACF3UO_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFD3657394.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(20653..22464)
                     /locus_tag="ACF3UO_001354"
     CDS             complement(20653..22464)
                     /locus_tag="ACF3UO_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFD3657395.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(22461..22826)
                     /locus_tag="ACF3UO_001355"
     CDS             complement(22461..22826)
                     /locus_tag="ACF3UO_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFD3657396.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(22989..23384)
                     /locus_tag="ACF3UO_001356"
     CDS             complement(22989..23384)
                     /locus_tag="ACF3UO_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3657397.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(23402..24364)
                     /locus_tag="ACF3UO_001357"
     CDS             complement(23402..24364)
                     /locus_tag="ACF3UO_001357"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFD3657398.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(24364..24576)
                     /locus_tag="ACF3UO_001358"
     CDS             complement(24364..24576)
                     /locus_tag="ACF3UO_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFD3657399.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(24597..25295)
                     /locus_tag="ACF3UO_001359"
     CDS             complement(24597..25295)
                     /locus_tag="ACF3UO_001359"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFD3657400.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(25315..25857)
                     /locus_tag="ACF3UO_001360"
     CDS             complement(25315..25857)
                     /locus_tag="ACF3UO_001360"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFD3657401.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(25989..26993)
                     /locus_tag="ACF3UO_001361"
     CDS             complement(25989..26993)
                     /locus_tag="ACF3UO_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD3657402.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(26990..27979)
                     /locus_tag="ACF3UO_001362"
     CDS             complement(26990..27979)
                     /locus_tag="ACF3UO_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD3657403.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(27976..28782)
                     /locus_tag="ACF3UO_001363"
     CDS             complement(27976..28782)
                     /locus_tag="ACF3UO_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657404.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            28948..29904
                     /locus_tag="ACF3UO_001364"
     CDS             28948..29904
                     /locus_tag="ACF3UO_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3657405.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(29981..30499)
                     /locus_tag="ACF3UO_001365"
     CDS             complement(29981..30499)
                     /locus_tag="ACF3UO_001365"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFD3657406.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(30587..30736)
                     /gene="rpmG"
                     /locus_tag="ACF3UO_001366"
     CDS             complement(30587..30736)
                     /gene="rpmG"
                     /locus_tag="ACF3UO_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD3657407.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            30964..31410
                     /locus_tag="ACF3UO_001367"
     CDS             30964..31410
                     /locus_tag="ACF3UO_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFD3657408.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(31605..33500)
                     /gene="asnB"
                     /locus_tag="ACF3UO_001368"
     CDS             complement(31605..33500)
                     /gene="asnB"
                     /locus_tag="ACF3UO_001368"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFD3657409.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(33825..34799)
                     /gene="bsh"
                     /locus_tag="ACF3UO_001369"
     CDS             complement(33825..34799)
                     /gene="bsh"
                     /locus_tag="ACF3UO_001369"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFD3657410.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(35133..35220)
                     /locus_tag="ACF3UO_001370"
     tRNA            complement(35133..35220)
                     /locus_tag="ACF3UO_001370"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(35186..35188),aa:Ser,seq:cga)
     gene            complement(35365..35931)
                     /locus_tag="ACF3UO_001371"
     CDS             complement(35365..35931)
                     /locus_tag="ACF3UO_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3657411.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            36187..37517
                     /locus_tag="ACF3UO_001372"
                     /pseudo
     CDS             36187..37517
                     /locus_tag="ACF3UO_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
     gene            37483..37833
                     /locus_tag="ACF3UO_001373"
     CDS             37483..37833
                     /locus_tag="ACF3UO_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657412.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(37925..38344)
                     /locus_tag="ACF3UO_001374"
                     /pseudo
     CDS             complement(37925..38344)
                     /locus_tag="ACF3UO_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(38345..38689)
                     /locus_tag="ACF3UO_001375"
     CDS             complement(38345..38689)
                     /locus_tag="ACF3UO_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFD3657413.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
BASE COUNT        11256 a         8074 c         6754 g        12774 t
ORIGIN      
        1 atgatccgcc cctctgtttt tatgatttta ttaaacttcc aataattctt tttctttatc
       61 agcagcgatc ttatctactt ctttgatgct gttatctgtc aatgtttgta cgtctttttc
      121 taatccgcgc aaatcatctt cggtaatatc accatttttt tgttgttttt tatattcatc
      181 gatcgcatca cgacggatgt tacgaatcgc gatttttgca ttttctgctt cttttttaac
      241 atctttagct aattcttttc tgcgttcttc tgtcagttgc gggataacta agcgaatgac
      301 atttccatca ttggttggac tgattccgat atcacttgcc ataatagctt tttcaacatc
      361 ttgaagaatg ctcttgtcaa aaggtgtgat cattaaaaca cgtgcttctg gaatttggat
      421 tgatgccatt tggttcaatg gtgttggcgc accgtagtag ttcacagtaa tacggtccaa
      481 aaggctagcg ttcgcacggc ctgcgcggat ttgcccaagt tcacgttgaa gattttgtgc
      541 tgcttttttc attttttctt ttgcttctgt cataattgca tctgccattt ttatttcccc
      601 cttacagttg ttccgatatt ttcgcctaag attgcacggc gaatatttcc gtgttcattt
      661 aaattgaaga caagcagtgg aatatcatta tccatgctta gtgaacttgc agttgaatcc
      721 atgacttgta atcctttggc aataacttcc agatgagtca gttcttcaaa ttttactgca
      781 tttgcatcta ctttcggatc agcagaataa acaccgtcta cattgttttt agccatcagg
      841 ataacatctg cgccgatttc tgccgcgcgt aatgctgctg ttgtgtctgt cgagaagtac
      901 gggttgccgg taccgcctgc aaagataacg atccgtcctt tttctaaatg acgttctgct
      961 ttacggcgaa tatatggctc tgcgatttga cgcatttcaa tcgaagtttg cacgcgtgtc
     1021 ggtacaccca cgttttccaa cgtatcctgt aaagctaagg cattcataac tgtagctaac
     1081 atacccatgt aatcagcttg agcacgttcc atgcccattt gtgctccgat ttgtccgcgc
     1141 cagatatttc cgccgcccac aacgattgcc atttcaacgc ccagctcgtg aacttctttg
     1201 atttcttgga tgatttcttt gattactggt ggtttgattc caaatcctgc gtccccagct
     1261 aaagcttctc cactcaattt taagactaca cgctgatatt tcggtgtgac catgttcatt
     1321 cctccaatat tttctattgc cattttacca tacttagatg atttcgacac tctaagactg
     1381 gtttttcttg ttttgcttaa aaaaagggag cgcacaaacc gtgcgttccc gtctgttatt
     1441 caacagaatt attttttcac ttggctcata acttcttcta caaagttatc ttcgcgtttt
     1501 tcgatacctt cgccaacttc gaaacgtacg aatgttttaa cagttgcgcc ttttgatgca
     1561 acgtattttt caacagtcat atcaggatct ttaacgaatg gttggtccac caaagcgatt
     1621 tctgctttga atttcttcaa gcgtccttct accatttttt caacgatatt cgctggtttg
     1681 ccttcgttca atgcttgttc tgtaagaaca gttttttcat gttctaattc agcttctgga
     1741 atttgtgatt cgtttacata acgaggattg atagctgcta cgtgcatagc tacgtctctt
     1801 gcaactgttt cgtcagttgt tccatctaga acagtcaata cggcaatacg tccgcccata
     1861 tgcaagtatc caccaaatgc agcattgtcg tctttttcta caacttcaaa gcgacggaag
     1921 ctgatttttt ctccgataac ttgagttgct tcgatcaagt cagattcaat tgtaccttta
     1981 tctgttttga ttttcattgc agcttccatg tctgctggtt tgttttcagc aacaagttct
     2041 gcaatttctt ttactaaatc ttggaacatt tcgtttttag aaacaaagtc tgtttctgag
     2101 tttacttcaa cgattgctgc agtgttacct ttcacagcaa ctgaagccaa tccttcagct
     2161 gcaatgcggt catttttctt cgcagccttt gccattcctt tttcacgtaa aagatcaact
     2221 gctttttcca tgtcgccttc tacttcaact aatgcttttt tcgcatccat cattcctacg
     2281 ccagtcattt cgcgtagttc ttttaccatt ttagctgtaa cgtctgccat gtttaactcc
     2341 tcctgtgtgt ttttcttttt aaaaaaagct gcttcaaagg agagtgaggc ttgtcgccca
     2401 gcctttgaaa cagctccatc attcaaaatt attctgctga agaattgtcg ccttcaacaa
     2461 catctacgat ttcttcgatt gatgttgctg tgttttcttc tgtgaaatct tcttcaacta
     2521 cttgatcttc accttggttt ccttcgatga aagcatcagc catttttgaa gtaatcaatt
     2581 taacggcacg aattgcatcg tcgtttgaag ggattactac gtcgatttca tctggatcgc
     2641 agtttgtatc aaccatagct acgattggga tatttaattt gtgtgcttct tgaacagcaa
     2701 tacgttcttt acgtgggtca acgatgtaca ttacatctgg gattcttggc atatcagcga
     2761 taccgcctaa gaatttttca agacgttcac gttctttgtt caaaccagca acttcttttt
     2821 taggtagaac ttcaaaagtt ccatcttctt ccattgcatt gatttgtttc aaacggctga
     2881 tacgtttttg gatagtatcc cagtttgtca atgttccgcc taaccaacga tggttaacga
     2941 agtattgtcc tgcacgagtt gcttcttctt tgattgcttc ttgtgcttgt ttttttgtac
     3001 ctacgaataa tgctacgccg ccttcttcag caacgctctt catgtaatca taagctgcat
     3061 ctactaattt aactgttttt tgcaagtcaa tgatgtagat tccgtttctt tctgtgaaga
     3121 tatatttctt catttttgga ttccagcgac gagtttggtg accaaagtgt acgccggctt
     3181 ctagtaattg tttcatagaa attactgcca tgtttgtttc ctccgatttg gttttatttt
     3241 tcctcttctt atcttctacc ttgccggcaa actttttcaa gcacctaccg acaatccaat
     3301 aagaatgtgg atttgctgat gcataaagca ccctcagcta ttatacagac aaaagatccg
     3361 tatcgcaaga gcaaatatac ttttctgctc aacattcaat agtttacctg aaagataaaa
     3421 agaattcaag aaaaacagta gatttctctt tgtttcttta ttatcctttt tccataaaat
     3481 aattttaggt ataaaagacg aatattattg ggcaatcctt cttttttttg ttatgataca
     3541 tgtgaaatct ttcgtaaagg agaaagaaaa tgcgcaaagc tcaaagacat ttgctgatta
     3601 aacaagtcat tgaagaattc ccgatccgta cgcaagaaga actattaaac aaacttgggc
     3661 attatggcgt taccgccacg caggcaacga tttctcgaga tatccgtgat ctaaaaatcg
     3721 tgaaggcacc tgatgaaaat ggcgtttccc gcttcgtatt gtttcgcgaa aaaggaactc
     3781 ctgagactag gactgaggaa gaggatcggc tggttcaaat gattgaagac attgtattga
     3841 aagtcgaacg agtccacttt ttgacgatcg tcaatacctt gccagacaat gctcatttat
     3901 ttgcatctgt tttagatgag atcaaacctc cctctattgt cagtacaatt gctggattcg
     3961 atacgatcat ggtcatctcg gaaaatgagg aggacgcaaa acgagtagaa gaatttcttc
     4021 accatccaac tgaagtatca cttttttaat cagagcacgt attcctaata tggaatgcgt
     4081 gtttttttat tttcaatatt ttccttattg aataaacctt tacactcttt acaaaaatac
     4141 atcatttttt attcaaattt ttcaacacct tgattgaatc acaataatca tcatttatat
     4201 tggatgttaa caagagcagc ttcttgctct ttgtgtattt caaaaaagaa atgaaaggaa
     4261 atcatatgta taaattatta acttctggac cattgacgac ttctgaaaca gtgaaaaatg
     4321 ctatgctgat cgatcattgt acttgggatc aagaatacaa agaaattaca caatggataa
     4381 gaaaagaatt attggatctt gctcaagtat cggaaggaat atacacaacg gtcttaatgc
     4441 aaggtagcag ctccttcggg gtagaatcgg tattaagttc tgtgatcagg ccagaagata
     4501 ctgtactgat ttgttcaaac ggcgcatata gacaacgaat gatcaacatg tgcgaatgtc
     4561 tgaaactgaa ctataccgtt tatgaggtat cggaacatca aatcctccaa gctcatgtga
     4621 ttacacagct gattgaagag aatccgtcta tctccgcact agcaatggtc catagcgaga
     4681 ctacttccgg tattttgaat aatttggaag agattgctgc tgtcacgcaa gaaagagatc
     4741 ttttgtttat agtggacgcg atgtcaagct ttggtgggat accgatttgt gtagccgaac
     4801 tagggattga ttttttgatt tccagctcaa acaaatgtat tcaaggtgtt ccaggctttt
     4861 cttttgtact tgctaataaa gcggaactgg aaaaacgaaa aaatgttagc cgaagtttgt
     4921 cacttgatct atatgaccag taccgcgtga tggaaaacga gaatggcaaa tggcgtttca
     4981 cttcccctac ccatacggtt ttggcttttc aacaagcgct gaaggaacta gaggcagaag
     5041 gaggaatcga aactcgatat tcacgttatc tcgccaataa tcatgtgcta cgacaaaaaa
     5101 tgacagagat ggggttccag cctttcattc aagaatatca ggggccattc atcacctctt
     5161 ttctttaccc taaggactgg cgatttgatt ttaatcattt ttatcagtat ttaaagcaaa
     5221 atggatttgt gatctatccc gggaaaatca gcgatcatga atgttttcgt atcggaaata
     5281 ttggcgagat ctatccggaa gatattttgg aactgacagc aattatcaaa gactataagg
     5341 agaacgttaa tgattaaaac tgtaattttt gattgggcag gaacaactgt ggactttggc
     5401 tgtatggctc ctgtccacgc ttttagaaat gcttttctag aaaaaggaat ccaactgact
     5461 gacaaagaaa tccgctaacc gatgggaaaa ttaaaatggg atcatatcca acagcttctt
     5521 tccctccctt ctgtcaaaaa acaatggata gctatttatg gacaactacc tcaggaaaaa
     5581 gaggtggagg aattgtatca acaatttgaa cattatctgt ttaaagattt ggtcaagcat
     5641 tctaccttga aacccgacac attggaaacg atcgaacggt tgagaaacgc tgggatcaat
     5701 attggttcca cgaatggatt taatgctcct atgatgacaa tcgtagcaga aaccgcaaaa
     5761 aaagaaaggt attcaccaga cttcatggca acttttgaag acgtcgaagg gtatggtcga
     5821 ccgtttcctt atatgatcca taaaaacatg cagtacttca aaaacaagtc ggttgatgaa
     5881 gtaatcaaag tcggagatac ggtctcagat atccaggaag ggaaaaatgc cggagtgttg
     5941 acagtaggtg taattgaagg tagttcgcta atggggattt cttatgatga gtaccaaaaa
     6001 ttagagatgg ggaaaaagat cgtttaaaac agtctgttgc tcttagattc caacaagccg
     6061 gcgctgatat ttgtgtaaac aatttaaaag agttaacaga atacattttg tacgctgaca
     6121 tgaatccaga atgactttta tacaaaataa gaggttgtga aaaagctgtc ctgtatcaag
     6181 taataaaaac agccaagcaa aaatagctcc tcatattttt cgtttggtta ggcttattac
     6241 cgcagatgca agcttttgaa caccgtttat tcgaaaaaaa aaagggagct gtgacacgac
     6301 ttttgtcaca gtccccttat ttgcaaacaa acagtgttta agagacaacc tctccactaa
     6361 acggtgttca ttcagctgac tctcggtatt tgctcaaaaa acgataaaat ttgaaaagct
     6421 attttctctt ttgtttctct aatactcgga tcagaacgct gatttcacat tctctttttc
     6481 ttacatctta tctggtgcat gaagtcctag caaacgaagg tcttctttca ataatacagt
     6541 cactgcataa actagagcta agcgtgcttc tttttgttca tcatcagcta aaatcttcgt
     6601 atgagcatag tatttgttga atgcttgtgc taatttgatt gcatgtttcg caatcactga
     6661 cggttcgtat ttttccccag cagacaagac cgtttcaggg tatttttgaa ctaatttaac
     6721 cacttcccag ctggtatcgt cattcaatgc atagtctgct gtttctgaag ggacaaatcc
     6781 tgctttttcc aacaggctga ctgcacgagc atgtgtatat tgcacataag gtccagtttc
     6841 tccttcaaat cgaacaactt cttccaggtt aaagtcaaat gtattcagtc gatcgttttt
     6901 caaatcgtgg aaaatgactg ccccaacccc aacttgttta gctacagcat ctttgttttc
     6961 caaatcaggg tttttctcgc tgatttgttc tttagcagat tggattgctt catttaatac
     7021 ttcttctaat aagacgatct ttcctttacg agttgataat tttttaccac cttgcgtgat
     7081 caaaccaaat ggaatatggt gcatgtcgtc agaccagtca aagcccattt ccttcaagac
     7141 agctttcaac tgtttaaaat gatagctttg ttcattccct actacatata gagattgttt
     7201 gaagtcgtaa gtacgtttac ggtacaatgc agcagctaag tcacgtgtaa tgtatagtgt
     7261 cgcaccgtct gacttcttaa tcaacgctgg attcaggtca taagcagata ggtcaacgat
     7321 ctctgcacct ttatcctcgt tcagcaaatg tttttcttct aaaagtttga cgatttcatc
     7381 catcttgtca ttgtagaaag cttcaccgtt caacgaatcg aaacgtactt ccagcagatc
     7441 atagatttta ttgaattctt tcatcgattc atcacggaac cattgccata attgaatagc
     7501 ctctttatcg ccttcttcca gacgtttgaa ccaagcacga gcttcttcat ttaattctgg
     7561 ttctgtttca gctacttcat ggaattggac gtataaacga agcaattcat tgattggttc
     7621 tgctttaaca gcttcttctg taccccattt tttgtaagcg acgatcagtt ttccaaactg
     7681 tgttccccag tcacctaaat ggttgatgcg gattggctga taaccgattt tttccataat
     7741 gaaaccgatc gaattaccga taactgtcga acgcaaatgt cccattgaga ttggtttggc
     7801 aatattagga gaagacatgt cgattggtac tgttccttga ttcccgatgt tgctatcccc
     7861 ataatgttct ttttctttca ctactgtttg caaaactttt ttgctgataa gttctttatt
     7921 catgaaaaag ttcaagtaag gtccgacaac ttcgattttt tcaaagttgg cagaatcgat
     7981 tttttctgct aaatctgcag cgatttgctg tggcgctttt cggtaaactt ttgctaatga
     8041 aaaggctgga aatgcaacat ctccgtgttc agctgatttt ggattttcta gtaattgctc
     8101 gacttgttcc agtgttaaat catctttgac agcgtcatag acagcttttg cgacaagatc
     8161 tttattattc atctttattc ctcctaaagt gttcccttga ttgttaaaca aaaaaaatct
     8221 ctagcgacgg catacttagt atgccatcac tagagacgag atttcccgcg gtaccactcc
     8281 aattgtccta aaaaaggacc agctccatct gatatcggta gacgaccgtc tgtttaaaac
     8341 agaattctcc aagtgcgctt cgttgtatct tcttcattcg gcttccacca cttccgaatt
     8401 cgctagccaa gaatgataca agtactctct tgttcaacaa atcttagtct tattaaactt
     8461 tcttgaatta tatcagaaaa aaaaacgaaa ggctagtcgt ttcataaaaa aacaatccag
     8521 atggcctaaa ggagaagaaa taccacctgg atagctataa atcatttcgt aaatacgaaa
     8581 gacttaacaa attaatcagc tacgataatc gttccttctt cagaagctaa aagattctcg
     8641 atattttcta aagaagtgat gattgcctta gcgtttggtt ttgcttcaac aaatgcaata
     8701 gctgcttcta ctttcggaag catgcttcct ggagcgaatt gcttttcatc aatgtattgt
     8761 ttcatttctg aaacagtaac agtttctaat ttcttttgat ctggtttttg gtaattgaca
     8821 tacacattgt ctactcctgt caatacgatc agcaaatccg catcgatgat ttcggctaat
     8881 ttttctgaag caaaatcttt atcgattacg gcttctcgtc cttctaatcc agtagctgtt
     8941 tctacaacag gaatcccacc gccaccaaca gagactgtga taactccttg atcgaccagc
     9001 gtttcgatga cacgtgcttc tttaatcgag atgggtttag gggaagcgac tacttttctc
     9061 catccacgtc cagcatcttc tttgaatgtc acagtggagt cagcattcat ttgttctttg
     9121 gcttcttctt ccgtgtagaa tggaccgact ggtttacttg gatttttgaa tgaaggatca
     9181 ttttcatcca caataacttg agtgactaaa gaaaccacat ctttatcgat ccctttttcc
     9241 ttcagtactt cgcccatggc gttttgtaac cagtaaccga tagatccttc tgtcattgca
     9301 acacatgtat ctaaaggcat tgccggtgtt ttctcagaat cagcagcttg ctgctgaatc
     9361 aataggttac cgacttgcgg accatttccg tgggagatga tcaattcatc tccttgttcg
     9421 ataaatttca ctaaatactt tgctgtttcc attaacgctt cttgttgggc ttttgcactt
     9481 gcatccgtag acaagatggc attgccccct aaagcgacaa ctacttttcg tttggccatt
     9541 tcattcgtcc tttcttcagt tctaccgaat tttctagata acaaaacgag ccagcgtttt
     9601 gtgattttcc ctcaatgctg actcgttttt tcgtgagatg aatgtggtta tgcttaaacg
     9661 cgagggataa acaagttacc taatgttgct gccatgatcg ctttgattga gtgcatacga
     9721 ttttctgctt ggtcaaattg acgagcatat ttgctgcgga agacttcatc tgttacttcc
     9781 atttcagtga tgccaaagcg ttctttcatt tgttcaccgt aaacagtgtt tgtatcatgg
     9841 aaagctggca agcagtgcaa gaagatcaaa cgatctgtgt tgtgtgtttt ttctaccatt
     9901 tccatattga tttggtaagg tttcaacaat ttgatacgtt cttcgaattt atcttcttca
     9961 cccattgata cccatacatc agaataaagg acgtctgctc cgtctacacc tttatcaaca
    10021 tcgtcggtaa tcatcaattg tgcaccggat ttttcagcaa agccttctgc cattttgacg
    10081 atttcttctt caggttgtaa ttcttttggt gcaacgatac gcatattcgc tcctaaaatt
    10141 gcacctgtga ctaataaaga gttagccata ttgtttcgac catctccgca gtaagcaaca
    10201 gtgatacctt ctactgttcc aaagttttct tggatagtta aaaagtcagc gatcatttgt
    10261 gttggatgcc attcatcagt caagccattc caaactggaa caccagagaa ttctgctagt
    10321 tcctctacca ttttttgact gaatccacgg aattcgattc cgtcaaacat acgtcctagt
    10381 actttagctg tatcttctgt ggattctttt ttacctaatt ggatatcatt tgcacctaga
    10441 tattcaggat gtgcacctag atcgatcgct gcagtagtaa atgcagaacg agtacgtgta
    10501 gatgtttttt caaataaaag cgcaatattt tttccttcta gatagtgatg tgggatacca
    10561 cgttttttca agtctttcaa gtgttctgaa aaatcgatca aatattgtaa ttcttctttt
    10621 gtaaagtctt tttctgctaa taagcttctt ccttggaata ctgattcttt catattaaac
    10681 attctccttt agattgtttt tatttaagat taaagaggaa atcccgacgg cagctgacag
    10741 taagactgcc gtcaggaaac aaattacttc aagtcttcac ggacaagtgg ttggctcatg
    10801 cagcgtggac caccacgacc tcgtgacaat tcacttgaat tgatttctaa cactttgatg
    10861 ccatagctac gaagcaattc gttcgataca taatttcggt tataagtgac tacaacacct
    10921 ggagcgattg ccaatgtgtt tgatccatca ttccattgtt ctcgaggtgc aacgatctca
    10981 tctccattac cagttgggat cagtacaaga tcatctaatc caagagcagc tttcatcgtt
    11041 tcgtgtaagt tatctgaatg agtaatcttg atatcatcac catctggttc gattgtaaag
    11101 acatccatct taccgtcttt actttgaatt gctggatgga tagtgaattt atcgtgatct
    11161 accattgtaa atacggtatc caaatgcatc attgcacggt tgttcggaat tttgattgcc
    11221 aacacttttt caaatcctga attttttgcg aataggtggc gtgctaattt ttctaaagct
    11281 ttcgcattag ttcgttgaga aatcccaaca gctactactt tatcgcttaa gatcaattcg
    11341 tctccgcctt cgatatgatc tggattttca cgatccaacc atacttcgat tcctttattt
    11401 gcaaatcttg gatgatgttt caaaatatat tctgtaaaca tcgattcacg acgacgtgct
    11461 tcaaaagtca tcttattgac tgtcatccca tttcccattg atgcggaagg gtcgcgtgta
    11521 aagtacaagt ttggcattgg gtccatgtaa aatggatagt catcgtctgc tgacagatca
    11581 tatagactgc tagaacgtac ttcgatatct tttgtacgaa ccccagccat gattttatct
    11641 accatttctt gcgtttccat tgatagaagg aactcatgaa gaccctctct tacagcattc
    11701 gatgcaatat gagattcatc caacatttta ttcaagaatt gttctttgac attgcctgcg
    11761 tcaatcgctt ctgccgctaa tttttccaag taaagagtct cgacgccttc attttgcaat
    11821 gtcttcgcaa agttgtcatg ttcttcttga gcaatcggaa gatatggaat atcatcgaac
    11881 aacagacgat ccataatatc tggtgtcaaa ttttccactt cttgtccagg ccgtttcagt
    11941 aaaactgtct ttaatttccc tatttcagag aaaacgtgaa taggtttatc catgttgtgt
    12001 tgcctccttc tttttgatta catgtatagg atatcctcct tttgtaatca ctttcataat
    12061 tttgtctcat tcaaaacgag acattcctca cattaatatt cgataattaa ataattaaac
    12121 gtttttctat ttttaagcgt aatttattca ttttttattc tgtatacact ttcaaaaaaa
    12181 tatttattca ttgaaaaaat ttttttgaat aaattaaaaa aataaattat attatcgttg
    12241 ttagcgttta ctatatgtat tattgttgtt ttttatacac aaatcattcg cttcaaaaca
    12301 aattattcaa taccattgta tattttttac ataataacaa attatatttg taaagtatta
    12361 aaacttgttt ctaatgttgg tatgttaaaa ctttacaaat tctttaaaaa aagtgacaat
    12421 aaatatagtg aacaataagg agaggacttt ttaatgcgtg ttaataaaat cgattttcac
    12481 ttttcaaaac tcagatatca acctgatttt gaacatttct cggatgaaga gttccaacag
    12541 atcaaggaac atactgttct tcgttcttat aaaaaaggac agatcctttt cgacgatggt
    12601 gatcccagac aacggttgta tatcttgacc aaaggactcg ttcgtttaga acgttatgat
    12661 gaaagtgcaa cttattacta ctatgactat gtgaatacaa ataacctttt tcctatgtca
    12721 ggaatgtttg gagaagagac ctacacttat acagctcaag cgatgactga tattgaaaca
    12781 ttctaccttc ctgtttccta ctatgaaaaa ttagcacgaa aaaatcccga acagttgatc
    12841 tatatgatac aaaaaatttc taaagtagtt gaaatacatg aattgcgtat ccaaatcgga
    12901 ttgacctcta gcgcctttga ccgggtaaaa caaaatttat tcattttgaa agaagaattg
    12961 ggcgtaccaa caaaagatgg tcatatcacc attccttatc cgatcacctt aaaagaatta
    13021 gcagtgaata gcggcacgac acgtgaaact gctggacaag taatcaaaca actacgtgat
    13081 tccgggctgt tagattatga caaaaagcgt tttactttct gtaagacagc tactactcca
    13141 gctatgagag aataacgcga acaaaaataa gcagtgaccc tgataaatat cagggtcact
    13201 gcttattttc ctccctaaaa cttctgaaag atccggcagt tttagatcac tggacaagac
    13261 tcaaagattt tctatgtgtg tttcagttat gtaatattca ctgtttgcaa aaaatactgt
    13321 tagattaact agatgaagcg tcttgtcctc atccgatcta gattattcga tattcctcga
    13381 caataaacga ttactcagtg agggcaatca gaggaacgga taatgataaa taagctgtaa
    13441 aaaatagcaa aataacaata atgattaaaa gtatgtaaaa aatagggctt tgacaaaaac
    13501 gtgtcacagc cctatttcga ttaaacggtg tgtacctgtc aactcttcgg tcacaagtca
    13561 taatgttcat aaacatgagg agctgttttt tgaaattgtt ccttgtgaat cagagttaaa
    13621 cgacaggctt acgaactctt gattaaacgg cgttcaaaag cttgcatacg cggtaataag
    13681 aacagccagg tcaaaaacat gagaagccgt ttttcctggg ctgttcttat tacttgatgc
    13741 agggcagctt tttcacaacc tctttattca gataaaacca agcttggatc agcattcaac
    13801 tgatagctag caaaatttct tttttgcatt tccacatgtg ctgctgctcc aatcattgca
    13861 gcattatctc cacaaagtcg aagaggggga atcactagtt ctacctcagg gagtttagct
    13921 gccaaagcat cctgcaatcc ttcacgcaac ccttgattgg ccgctacacc tccagctata
    13981 atcagttgct tgactggata attttgacaa gctcgaagtg ttttagtaat caatacatcg
    14041 atcacacttg cttgaaagct agctgctaaa tcatttttgt ctagatcttc tccacgctgt
    14101 tgtgcattat gcaccaaatt gataaatgca ctttttaatc cgctaaaact gaaatcataa
    14161 ttatcttcat ggatcatcgc tcgcggaaaa tggtaattat cttttccctg atgagctagc
    14221 tgatcgattt cttttccgct tgggtaagaa agacctaata ctcttccaac tttgtcataa
    14281 gcttctcctg ctgcgtcatc tcttgtctcc ccaatgattt catatgatcc atcttcttgc
    14341 atatagacta attctgtatg tcctccgcta acaagaagtg ccatcaatgg aaactggaat
    14401 ggtttaacca gacgggctgc atagatatgc cctgccatat ggtttacagg aataagcggc
    14461 aattggtgtg cccaagcaaa agccttagct gcagaaatac caatcagcaa cgagccgaca
    14521 agtcctggtc cataagtgac agcgactgcc gataaatctt ctgccgacac accagcttct
    14581 accagtgcat cttccaagca taaggtgatt tgttctacgt gatggcggct agctacttca
    14641 ggtactacgc caccaaaacg tttatgactg tttatttgag aagcaacgat gttagataag
    14701 atctctgttc catttctaac gaccgctaca ctcgtttcat cacaacttga ttcaatcgcc
    14761 agaatcaatt cttcattcat ttcatcgtct ccgtttttaa ctttctgctc ataatgatcg
    14821 catcttccgt cggattgcga taatatgatt tccgtttacc taatatacga aacttttctg
    14881 attcataaag ttttcttgct gcttcattag atagacgtac ttctaaaaaa acatgcagcg
    14941 aatcttttat ttgttccgta atcagtaatt gtaacaaatg ccgtgcatgc ccttttcctt
    15001 gttctgaaac tgcaacagca atatttgtga tctcgacttc atctattact ttcgagtatc
    15061 caataaagcc acagatctgg ttatcttcag ctaaaagcag ataatcagag tgaggctgtt
    15121 ggatgtctgc caaaaactgc attttcgtcc aaggtgaacc atgtggataa gcattttcgc
    15181 taatcatcca tacgcattct gccaagtacg cttcatcaaa atcttttttt ctgcaaatca
    15241 actaatctca ctcattttct aaaagtttta tcatatccaa cgcatcttct tttgtttcag
    15301 tgtaatatct ttttttgatc gttgttgctt gaaaccccaa tttccgataa agtctttgtg
    15361 catcttgatt actcatacgc acttctaatg acatcgtctc acagcgattc attatagcaa
    15421 agttctcgat ttcgtcaata agcagcgaac cgattcgttt acgctgatat gccggtcgaa
    15481 cggcaatatt cgtgatatgg caatctaaac cgaacgctct tgaaccgata aaaccaatca
    15541 ttcttccatt atcaaagata cctagatata gatgaggaag cggtgacttc aattctgata
    15601 taaaggcact ttttgtccat ggcaattcgc cattatagac ttctcgttcg acatccagca
    15661 gctctttgat atcttctgta gtcaattctc ttagtacgta acgacgatcg atttgttcga
    15721 ctgttttttc tgtataaatc attttatctt gaaaaaagct tctggcatac gctctaaatt
    15781 ttttcaacat aactttcgtc tccaggtgtg tgcgtctcca accatttttc ttctgcttct
    15841 actcgtttta aatagcgagg aagaaaagct tgtttctctg caactggttc aactaaagca
    15901 cctaattgag ccacagttac accacttgga atatcccatg ctggaactgt attaatcatc
    15961 gcactaggca atatttcctt tatttcagag aagaatttgt gacaatcact cccgacgaaa
    16021 taaatagctt cattcagctt ttgtagttgt gtgaacaaat cagaagcaga aatatgtaca
    16081 tcttcaagta cagtttctaa tctattttct ttccagcggt atgccccagc gtatacattt
    16141 tttcttcgag catcaaacat gggcacaata atattatcca caccgatgca attagccgcg
    16201 atggttttca gactagatac tcctactagc tctttatcta atgtataagc aatcgttttt
    16261 gctgtcgtta cacctatacg aagccctgta taagaaccgg gaccatcaga aaccgcgatt
    16321 cggtcaatgt cttttggact tatttgaaga tctgcaaaca attggtcgat tgcaggcatc
    16381 agtgttacac tgtggttgcg tttgatattt gtttgtattt gtccaagaat ttgttcgtct
    16441 tctaccacac cgatcgccaa agtttggttt gcagtatcta ttcctaatgt aatcatatat
    16501 ttgatccttt ctgctatgac attctcgcct tccattgtag catacttttt tattctgagg
    16561 atgaaaatac caaaggcaaa actagtacaa taatacatga ttatctgctg gcgggcaaat
    16621 tttgcccctt cctgaaacac aaaaaagctg cggtatcact ccattttccc acagcttttc
    16681 catcttttat ttcgttgatt ctcgaataat caactctgtt tccacaataa tctttcttga
    16741 aaccggtgct ttggaattac ttaattgaag aatcgtctcc actgctagct ctcccatcca
    16801 ttcggtataa acttttacag tagaaagcga gggcgttaca tatttcgcta cactgacatc
    16861 attgaagccc atcacagaaa tatcttctgg taccactaaa cctttttctt gaatcgcttt
    16921 cagtgcgcca atcgctaatg catcattagc tgcaaaaagc gcatcaggaa catgcggatt
    16981 cgtttttaaa tattgcttca ctgcttgata tcctgactcg acagaaaaat ctgcttcgat
    17041 aattggacct tcgtcgtagc ctttttctgc caaaacttgt tgaaatgcca taattctggg
    17101 atcttttagc cgctgatggt ttttcttcgt atattctgtt ccagcaagca tagcgatatg
    17161 ttgcgcttta tgggagacaa agtgttcaat gactttttga acacttgact taaagtcgac
    17221 aactagagag tcgattcctt gagaagtgcc gtcagaatct accaaaagca aggcattttg
    17281 ggatcctttc atttctaata actgagcttc gtcgaatttt cctagtgcga tcgttccatc
    17341 tgccggaaga tcactaatgg aatcccacgt ttctttcaat aaagtaacgt ttgcttcttc
    17401 tgcctttttt tcgattccta ggcgaataga taaataataa agatcttcaa gctcttccgt
    17461 atcgtcgtac cactggatca ggcgaagcgt ttgcttagta tttgctgcat ttttacgatg
    17521 tttcgtataa tttaagcgtt ctgctgcttc aaaaattttt tgctttgttg ctaagccaac
    17581 ggaaagatca ggatcatagt tgagaactct tgaaacagta gcaggagaaa ctcctgccaa
    17641 ctgcgcaatg tctttaattg ttgccatttg tctctcctcc ttttttacgt ttataaaatc
    17701 gcagtaaatc gttcaaacgc tgcctgtcct ttttcatctc gcttgaatac tccagcgtct
    17761 tccagtacac gtgcaaaaac ctgacctaca gatttttgta cgacatcggt gaccgtatct
    17821 ttcgtcaaat caggatgttc tttttttaat tgttctgccc acggacgatg atattcagcc
    17881 atctggtttt cttctcctaa taagaaatgc tctacttcta ctagttctgg tttcaaacga
    17941 ggtggtaaaa cagcaagccc cattacttcg atcaacccaa tgttctcctt tttgatatgt
    18001 tggacatctt tatgtggatg aaaaatccca tcaggatgtt cttctgaaac attgttgtct
    18061 cgaaggacaa ggtccaactc aaagtaattg tcccttcttc gtgcaattgg cgtaatcgta
    18121 tggtgtggtg taccatctgc tgaaaaagct ctgatagata ctgtttcatc cgaatatgct
    18181 ttccattttt ccaatactga gttagctgct tcaataagca agtttttctc tgttgattgc
    18241 aaacggatca cagacatcgg ccatttcacg actcctgcga tgacttgcgg ataatcttct
    18301 agtttgataa gtttttctat cggtgctttt gccataggaa attcatgacg tcctgcctga
    18361 taatgatcat gagaaagaat cgatcctcca acaattggta agtcagcatt cgaaccaaca
    18421 aagtaatgag gcaagacttc agtaatccga agcagtctag caaatgtttc ctttgtgatt
    18481 ttcatcgggc ggtgttgttc tgataaaatg atcgaatgtt cattgtaata agcataaggg
    18541 gaatattgga atccccagct ttcaccgtct agattcattc gaataatccg gtgattggtg
    18601 cgggctggat agttcaagcg acctctatat ccttcgtttt ccatgcaaag catgcaggta
    18661 ggatagtcta cttttaccgc ctcgcgttct gctgcgattt gttttggatc tttttctggc
    18721 ttagataaat tgattgtgat ttccagttca ccatactccg actctgccgg aaatttgatg
    18781 ttttttgcga tggctcttgt tttgatgtag tcatttttct tacttaaatt aaagaaatac
    18841 tcagttgctt cctctgggct tttcgaatag tgctgtgcaa agaatgcatt gacgactgaa
    18901 ggtggcggtg tgagaaaatc cattaattgc gcttcaaaaa tctcttgttc tgctggcaat
    18961 tctgaaagaa caccattttc tcttgcctta gcgacaagct gatccaataa gtctacagat
    19021 tcttccttaa ctggtcttac ttcaatgctt tctagagcat cttctcctac catccctaaa
    19081 agacgattct gtaaatataa gcggtccatt tccatccatc cgccagcttc gatcgcaagt
    19141 gtggcaaaat cacaaatcgt ttgactgatt gacatatctc attcccctat tcttcataac
    19201 catttggatg gctgacatgc caatcccatg ctgttttgat aatcgctttg atatctgtgt
    19261 attcaggttt ccagcccaga atctctctcg ctttttcact tgaagcgact aatcggctag
    19321 gatctccagc tcttcttggt gctatttctg ctggaatttc ttttcctgtc acttctctag
    19381 ctgcttctag catttccttg actgagtatc ctttgctgct gcctaaattg aagaagttgc
    19441 tttcatttcc ttctttcaag tattccaaag ctaaaatatg tgcagcaatc aaatcttcta
    19501 cttgaacata atctctgata catgttccat ctggtgtatc ataatcgtct ccataaacag
    19561 ccaaggcttt tctttgacca agagctactt gtaaaatgat tgggacaaga tgcgtttctg
    19621 gtgtatgatc ttctccgata gatgcatctg cttttgctcc ggctacattg aagtagcgca
    19681 aagcgacata gcgcatgcca tatgcttggt cacaccactt catcattttt tccatcatca
    19741 atttactttc accatacgga tttttaggat tagctggtgt atcttctgtg attggagact
    19801 ctttcggctc tccataagtt gctgcagtag aagagaatac gattttattc acgttgaact
    19861 cgtgcatgac ttcaagtaag atttgcatac cgtatacgtt gttgttgaaa tacatcaatg
    19921 gtttttcgac agattctcct actaaagagc ttgcagcaaa atggattact ccttcaatcg
    19981 gttccttttc aaatacggaa cgtagaaatt ctttatcccg gatgtctcct tcataaaaat
    20041 gagcatctgg atgtactgct tgtttgtgac ctgtgagcaa attatctacc acagctactt
    20101 gatacccctt ttgaactagc tggtctacag cgtgcgaacc gatataaccg gctccgccta
    20161 gtactaaaat tgtcataaaa aacactcctt tgattagtaa aattgtgttt gttgattcta
    20221 tataatttaa aaaacgaagt ttacttttat ggtgaaaaca aacaaagtaa aatttcgtaa
    20281 attcatatgg taaatttata ataaaacatt tagtaaacat tttcaagggt tttttgcaaa
    20341 ggtttacaaa caaacgtaaa actagccttt ttttctcttt tgttccataa tagatataac
    20401 aaataataaa tgaggtggat tcaatgaaaa aatttgtatc tggaatatta gtaggaagtc
    20461 tggcaacagc cgctgccgtt gctggtttgg ttgcttctgt gaaaaaaaca gtgatcgatc
    20521 caattgacga aaaagaagca atgatcgaag aaaaccgtaa aaaagcaatg cgtaaacgcg
    20581 tttctcgtta ataattattt aaaaatacgc atgaagactt tctaaaaaac agataagtca
    20641 tcatgcgtat ttttatttgt cagtcaatat aagttgtgct attttatctg cctgtctcag
    20701 attccatgga tctgtataag gtctagctac tgctgcagtt agccaatcca caccttcaac
    20761 aggtattcca tagcaataaa agtcagactg gatttcccct gaagcatcaa tcacgcgatt
    20821 cgtacctcgc tcaacatcta tagcttctga atgataactt cctgtattat ctgaaaatga
    20881 aaaagggcga acaagtttgt tttccttcaa attttttatg acaggattac ttgaacgaga
    20941 aaagcttgtt tgtggcaatc gagcttcaat caaatagcga ctgctgattt ctttatcttg
    21001 tagagaaata acatagcggt tgtgcttttg ctgaatatca aatggcggtt cgatcaaatg
    21061 aaaaataccc gcatctatca gtgctgctaa ttctttcgtc cgaatgattg gcggaccgat
    21121 cgttaaaaag ctatttagat gagtaaacca tccccatagt atttctttgt attccttagc
    21181 agaaaaaacg tgccattcaa tagcctgccg gattggatca cgccagtctt ttaatgcatc
    21241 aaatgttgaa gcaaatgctc ctgtgcaatt gcctttttcc gcttctttta tctgcccttc
    21301 aataaatatt cggctagctt ctgaaaaggg ctcattctga taggcaagag gagtttctaa
    21361 atacgaccaa tcccatctat aagggattag tgctggatgc tttccgagac actcctctga
    21421 agagagggag agaaaatcat gctcaaaatt tttctttgga atcggcaagt gatattcttc
    21481 gatgattttc ttgtaataaa acaactcaac gtcttttttc agatagtcaa aaaatgtttc
    21541 gccagtcaaa aatcccgact gatgccattg ctccaggttt tcttttgtta gtaaccgtgg
    21601 ccatgccatt gctccgcctt gcttttgatt tcttcctcga gggtaataag ggagccccct
    21661 tcttgatcca ctgtatacaa tcggttcctt gcctgatgga tgatagacca gttttccctt
    21721 ttcgttctcg aagcgccctc ctcttgatac tgtaaacaat ccgacataat caaaaaaact
    21781 taagcctaga cctcttaaaa agacattttc tttaggcggt atcttcgaaa gatctacatc
    21841 tgcaggatta gaaggaagct gatacagtaa aacatttttc tttgcgtagt ctacccacac
    21901 tctttcttct tctgtctcat cattttccca gtgaccgctt gctaaaacaa gctgatcgat
    21961 agaatagctt tgctgatctg tctgtaaaag ataaccatct tttcttttgc ttactttttt
    22021 tactaaagaa taaacaaact gaatagaagc tggaaattct tcttgcaact ttgagaaaaa
    22081 ccagcgttga tagagtccgt ataaacatcg agtagattgc tgatcttttt ccagacgatt
    22141 gatttcttct ataattagtt gcttattttt ggttaccgtc tgttcgatat aatctgtagc
    22201 aggtccttta ctccattgaa acaagttggg tccctgtgtt accaatcctc cactggacaa
    22261 tgtttcatct gtaaaaagcg tcacttgttg agaaacagaa ttcattaata actccggtgg
    22321 ctgattcaac cgccaaactc gacctccagg accattggga tcgaaaagaa aaagttcaag
    22381 agaatgtctg tcctgattat tatggagaat cctttctgct acacttaatc ctctaggtcc
    22441 ggcaccaatg atccctattt tcatttgcat gcctccattt cgataaattt tttcaataaa
    22501 acagcatggt tctgatgttc attttttgca ccataaacaa aagtaatgac tggatgttct
    22561 ttcataagtt gactgagttt aaaaatagct tgcttctttt cttcttcgaa aatcaattct
    22621 tgctggtatt tctttgcaaa tgaagcaaat cgttctggta catggtcaaa agttttgcgt
    22681 gcttcattac taggtgcaat ttctttcaac cacagatcta actgcgcttt ttcttttgaa
    22741 attcctcgtg gccagaatct atccacgagt attctatagc catcctcttt ttcagcatca
    22801 aggtaaacac gttttaattt gatcatagtt gtttccttct ttctaccttt tcgcttagct
    22861 tatatatgta gataatagca caaaataaaa aaaatgaacg gcacaactat ccattgcgcc
    22921 gttcatgtga tcttggtcaa aatctaatga ttgattcggt ttttaaagct gtcatacaat
    22981 catctgtttt atactttttt acttttgatt tttccagacc atccgtcata tccaccctta
    23041 agtaaataaa tctcttgata acctgcttta cgtaatttat ttgctgtacg gatgctcaaa
    23101 cttttctttt gatcgtaaat atagacaggc tggtcttttc gaatagatcc taatgaatct
    23161 ttcaaaacag tgtaagggat gtttcttgca cctaaaatat gcccagcatc aaacacatct
    23221 ttttcgcgaa catcgattac ttgtgctttt ctcattcctt ctcgaaattc ttcttctgtc
    23281 aaagtcgttg ctgaacgttt ggccattact cgtagataga cttcccaaag gatgattgca
    23341 agcacaatca atagcaaaat gatattaatt acccataaaa ccatgtaatg cctccgtttt
    23401 tttaagcaaa tttcaaggct aatgaggcag caccaatgac accagcttca ttaccaagct
    23461 ctgctaattt gatttttgtt gattctctta cttgcgggaa agtaaattct ttaaaatatt
    23521 tctctacacg gctacgtaaa aattctcctg ctgccgatac tcctccacct aacacgatac
    23581 ttgacggatt taatgtattc cccaagtttc cgcaagctaa acctaagtag aagcatacgc
    23641 gatcaacaac catcaatgca aacggatcgt cttcttgagc catttcaaag atatctttac
    23701 ttgttacttc ttctccgttg tctagcattg ctttcagttt tgaatcccct gcgtattctt
    23761 ctgccaagaa acgacctagg cgtaccacac ctgtagcgct agatacagtt tctaaacatc
    23821 cgcgtttacc gcaagtacat tcgaaccctt caggatccac agtgatatgt ccgatttctc
    23881 ctccagctcc gctcacgccg tgaatcaaat ttccgccagc aacgatacct ccgccaacac
    23941 ctgttcctag agtaacgaat acaacgtctg gatcgttttc tccagcacct ttccatcgtt
    24001 cacctaaagc agcaacattc gcgtcattat cgatagcgaa tttgattcct gttcctgcct
    24061 cgatcagttt tttcacaaat tgaacttctg tccagtttaa gttatacgca ccaataaccg
    24121 ttccagcttc gctgtccacg cttcctgggg tacccatgcc gattccgata aagtcttcgg
    24181 ctttcatatt atataaattc aaacgatgat tgattgattc aatgatttca ggaacgatat
    24241 gcttaccatc atccaaaata ttggtatcga tgctccattt ttgctgaatc tctccttctg
    24301 gtgttaaaat tgcaaatttt gctgttgttc cacctaaatc aatcccaata atcttcttgt
    24361 ccattacaaa tttcctttct ttcggctttc ttcaattcgg tgctctcttt ttaatatgcg
    24421 ccacgctgtc atgtatgtat catgatcaat caaacggcta tcatacagat tacgcaattc
    24481 gatagtcatt aattcaatgt catagatgcg tgcacccaca tagataaaga tgccaaattt
    24541 tttgaacagc tgctgtacat catataagct ctccatcttt aagcacttcc ttcatattat
    24601 acaagtaaac catatttttt taaacccagt aaaatacata ttacaaaaag aaatacaaaa
    24661 actagtgtag aaagaatcct ttggtgtatc gaatagcttg tctgttgttt cggtagaccc
    24721 aaaacattcc ctaacactaa tccgccaatt agcccaccga catgtcccca aacatctaca
    24781 gaggtatcca gaagaccaaa aacaaatgtc aacacaataa ataaaagaaa atgtctgact
    24841 agctgctgga tcgctgggtt atgtttaaaa tgaaacccta agataaacaa cgcaccgaac
    24901 aaaccgaata tcgaagtact tgcaccacca gacagaacat tcgcttcgtt aaaagcaaag
    24961 cttgctgtat ttcccattat cccgctgaac atataaatca agaaaaaacg ccaatggcca
    25021 tagattgcct cgatttgctg ccccataaaa tacagtatca gtgagttcat tacgaaatgc
    25081 atcagtccaa aatggatgaa gattggtgtc actaaacgcc accattcatt gaagtgaaca
    25141 agataaggac catacattcc ggcataataa gggatctcaa gtcgcggaaa taattccatc
    25201 atgaggaaga ccgctgtctg tatccctaaa aaagcatagg tccataacgg tcgtcttaac
    25261 catgcacgca attttatttg ctgttgataa ttcatgaaaa cctcccattt cattttagtc
    25321 aataaacaat tgttggatct tctgatcaaa gctctccggt tgccattgtt cattcaattg
    25381 ttcacgaaaa acaaggctac atgttttttt atgaaaatta tttaaatacc ggtcgtaata
    25441 accaccgcca aaaccgattc gataaccggc tctattgtag ataatacctg gtacaatgag
    25501 gagatcgatc atctccggca aatagagctt ctctgattgt ggctcaagaa caccaaaact
    25561 cgaacgtaca agaacggact gttcatccat ttcataaaac gccatctgac gtttcggcaa
    25621 agttttaggt acaactattt tcttttgttc tttttctgct cgttggataa ccggctgtgt
    25681 atccagttca aattcattcg ataaagtcgt ccctatcact tttgctgact tccagtactc
    25741 gctggcgaat agctgtttat agattcgctg ttctttttcc tttttcttgc cacttttggc
    25801 cagatttttc agcttttcga ttcctttccg gcgtaatctt actttcaatt ggtccaaaaa
    25861 ctcacccttc cttctctcat aaaatggtat aggaaaaaaa gaaaaatagc aatcgaactt
    25921 tcaaataaat gcataaatag aataaaaaga agacctagaa atgattggcc ttcctttttt
    25981 aatgaatttc aactgttcag cgcgtgtttt tgtctgataa aaagtgcata cagaaaatat
    26041 ggcgcaccaa aaagggcaat caaaattcct gtaggtactt ccccacttag tagaatcact
    26101 ctagcaacca tatctgcact aagcagaaaa atggaaccga acaaaccgct cagaacaaag
    26161 gtccagttat tttctttacg tacgactagc ttcgcagcat gaggagctag tagtcctaca
    26221 aaagataaac tacctgtcac cgctacacta ccgcttgcca aagcaacagc taacaacaaa
    26281 aggatttttt gacttttagc cacgttaagg cctaatcctt gcgcgcgttc ttgaccaaat
    26341 gatagcaata caatcctctg tgcataaagt cctcctagcg gaattaagat aaccgcccat
    26401 ggaagcaatg cccaaacata aggccagctc gcaccccaga ttgatcccgc taaccatgca
    26461 ttcacaaatc cataattttc cttagataat tggatcgtgc atagcaatgt taatgcagaa
    26521 aggccggcat taacggcaat accggacaat aagattcgat tcatacccaa aaagccattt
    26581 cgatcatagg ccgcaagata gacacagcaa gcagctaaaa caccacctag aaaggctaca
    26641 actagcaata gaaacggcag cgaatagtgc gaaaagaaac ctaaataaag catcactaaa
    26701 aatcctgctc cggcattaat gcccaatata ctagaatctg ccaattcatt tcttgttact
    26761 ccttgcaaga tataaccaga aacgccaaga caagctcctg ctaataaact gatcagtaat
    26821 cgaggaactc gaaattctct aacaatcagc gccaaagaag atgattcttt ccctatgaac
    26881 gtggcaaaaa gctgatccag gtaaataaaa ggcgtaccaa tcattaaact acctatagac
    26941 aggatgacaa gtacaaaaag caagaaatag aacgtccaat atattttttt caccgttgtt
    27001 ccctccttac ttgtatcagt aaaaacggaa cgccaatcaa tgcaatgact aatccaaaag
    27061 gtgtttcaaa agggggattg atcatcctcg ctgtaaaatc cgccaacata accaatccac
    27121 cgccaactaa aaaagagaca ggtagaacat aacgatagtc cgttccaacc attccgcgaa
    27181 caactggcgg aaccaacagc ccaataaatg aaacaggtcc gactaacgaa acggcaatgg
    27241 ctgctaacac tgcaactaga cagaaaacaa tcaaccgcgt tcgtttagga tgacttccaa
    27301 gagctaatgc atgtgtttca ctcaaatgaa tcaaagatat tgcttttcct aatgaaaaag
    27361 aaaccaaaac agcaagtata tataaaggaa acaatactgc taattgtttc catgtgatat
    27421 tggcagctcc gcctacaaac caaaaagcaa gatcctgctg cagattaaag aattgggtaa
    27481 gtgcttggct gatagcagta aaaaaagaac taatagctac gccagctaaa atcagctgta
    27541 aaggattcat gcccattttc gaaaactgca aaaaaccaaa tacgagcaaa gttacagcaa
    27601 aagaacctgc caatgacatt agaaacacag aaaaatcaga agctttaggc caaaaagcaa
    27661 aactaagggc cattgccaac gaagcacccg cgttgattcc tagtaagcct gaatctgcta
    27721 aaggatttct tgtcactcct tgcatcaatg caccgctcaa tgcaaaacaa ctccctacaa
    27781 gaaatgctcc cgccacacga ggcaaacgaa tatttcgtat gatttggtga ctttgttttg
    27841 atctatcaaa atcaaacaac gcctgccaaa aatctgcttt tcccacagtc gctgcgccat
    27901 ttgaaagagc aacaaaaaaa ataatcaaaa gaacaaaaca gaccaaaagc aggagtctat
    27961 ttttcttcat agtcctcata attgatcctc ctgctctttt ggcaacaaat cataggttag
    28021 aaaaactggt ttatttgttc ttggaagcgt gacaatcgtt gcatcaatct caaatatttt
    28081 tttcatacac tcttttgtga tcacttcttc aggtgtacct tctgtgatca acttaccgtt
    28141 tttcattgct aataaataat ctgaaaaacg tgaagcatga ttaatgtcat gaatcgacat
    28201 caagatcgtt gtttgtttca tttgattgat ttcagtcaat aactgtagga tctctaattg
    28261 gtgtgccgga tctaaaaatg ttgtcggttc atccaagatc aagatatctg tttcctgagc
    28321 aagcgccata gcgatccaga cacgctgggt ttgtccacca gacagcgttg cgatatcccg
    28381 catacgaaat ccagctagac ctgtagcatc caacgcccac tcgattgctt catgatcttg
    28441 cgtgtccatg ccactgaaca gtttttgata agggtatcgt ccgtaagata ctacttcttc
    28501 tactgtcata cctgtagggt gttcactagt ttgtgctaat aatgcaattt tttttgcaag
    28561 ttcttttgaa ctgtatgtag agatatcaga gttattgaca atgatctttc ctgatttcac
    28621 aggtagtata cgggtaaaac ttttcaataa agtagatttt ccacttccat ttggcccaat
    28681 caaactagtg attttccctt caggaatcgt aacagacatg ttttcaatga tttttttgtt
    28741 ttcgtagccg gctgcaatgt cagctgctct taatctcgtc atttcaccca tcctttcgct
    28801 gaaaatcatt ctcaattatg acgctgtttc aacatttcgt caagcgctac tttcatatct
    28861 atagccaaat gaagcggttg acagcgttcg aaatatcagg aataataacc aatgagaaag
    28921 attctcaatt atgttaggag gaaagaaatg aaattaaaaa caaaagtatt cacattatct
    28981 agcatattgc tgctggctgg agtactgagc gcttgctccc cctcttcaga taaagaaaca
    29041 gctacaactg ccaattcgac gacttcatcc aatagtactc atacagtcac agatacactt
    29101 ggacataaag tagagattcc aaacgcgccc aaacggatca tcggcagtta cttagaagac
    29161 tatctgattg cactagggga aaaacctatc gcccagtgga ctgttggcag tggttccatt
    29221 caagattatc tgcaagatga tttaaaggat gtcccaacga tttcttatga ccttccttat
    29281 gagaaagtgt taagctttga gcctgatttg ctgttgattt cttcttccgc tactgtcgaa
    29341 ggcgggaaat acgaacaata tagcaaaatc gcgccaactt atgttgtaaa aaacggaaca
    29401 gatgtcacat gggaagaaca actaaaagat gtcggcaaag ctttggcaaa agaaaaagag
    29461 gcagaaaaga tcatttccga ttatcaaaaa tccatcaaga aaactcgaga agaactagca
    29521 gataaaatcg agaacaagac agctgcagtg ttgtgggtga ccaacaactc agcctttatg
    29581 gtcagcaaaa atcggtcaag tggaagaatc gtatacgacg atctggaatt tggtgttcct
    29641 gatctagtgg aagaggtctc caaaaaagcc acttctgact ggtctgctgt ttcctctgaa
    29701 aagctagctg aattagatgc tgactacatc atccttgtga acagtgacaa agatgctgcc
    29761 atgttcaatg aaccaagctg gaagaatctt aaagcagtga cagacaatca tgtactgcaa
    29821 ttcggacctg aatctagttg gctatataac ggacctattg ccagtcagga aatggtcaat
    29881 gatatcaaag aaaaactaaa ttgattttaa ctaaaaaaag catcttcacg attagtcgtg
    29941 atatgctttt tttcttatta acaaactaga cgcatagatt ttattcttct tttgaagcaa
    30001 ccctattttt tactctttcc catttttgaa aacgatgggc atatagattt tcttgatccg
    30061 ttatcccctc atactcctct ataagggcga agtctgaaaa atcaatattc ccaatatacg
    30121 tatcgccttc aaacgtgcta tcgatcaatg ttcgccagat ccgaccagtg taaggaagaa
    30181 gttcttgaaa aatccgacta ccacccgaaa catagatatc ttctgagatc gtttgactat
    30241 acgacaaaag ttcatcgatc gaatgcatta cttccgcatt ttctttcgtg cgaaaatttg
    30301 gctgcgttgt caacacgatg atatggcgat aaggaagtga aagatccccc attccttcat
    30361 aggtctttct tcccatcact aaaattcgat ccattgtatg ttcgcgaaag aaacgcatat
    30421 catttggcaa tcgccatggt aacaaaccat ttttgccgat cagaccattt ttatcttgtg
    30481 cccacatgga aataaacata ttatccgctc cttatgattt tagatgtttt gagataaaaa
    30541 aagtctcaat tctttgacca gcaaggaatt gagaacttta aaaacattat tttgtttcac
    30601 ggtgcaaagt aactttgcgt tcgcgtgggc aatatttttg tttttccaaa cgatcaggat
    30661 tgttacgttt gtttttgctt gttagatagt tacgttcttt acaagaagta cactctaaag
    30721 tgatgtttac gcgcatgttt ttccctccca tttttacaag aatcctctaa gatgactctc
    30781 agacttgatt atcttaccat gattttttct agattgctag tgtttttcac gattttgtta
    30841 agtaaaacta cttgacgata aatacaacgg ttttacttct caaacaaaat ctttttcttt
    30901 ttgtataaat acccttacac ttgtttatat agattatgtt ttttaataaa gggggatact
    30961 aatatgccat ggaacatgaa ggactttcct gcatcaatga aaaacttaga taaattgaca
    31021 agaaaaaaag caatcgacat cgcaaatgca ttattagatg aagggtaccc tgataaccgt
    31081 gcgatcccaa ttgccattga tcaagcaaaa aaatggtatg aagatgctag tgaatcagaa
    31141 aaacgaactt tcgaaaaaga aaaaaatcca agcaagacgg atgaacacga tacgaatcct
    31201 cgtgctggaa aactgcttga ttcagatgtg atcgtagaat atgaggaaga acaatggatc
    31261 gtgaaatcta aaggggcaaa aaaggcaagc aaccattttg atacaaaaaa agaagcaatc
    31321 gaaaaaggaa agcaagtagc acaaaacaaa gaatcaactt tgttcattta taaaaaagat
    31381 gggacaaaag aaaaagaaat cgattattga acatatgtaa aggggttgtg acgaaaatcg
    31441 tgtcacaacc cccttatgtt cgaaacaatg gtgttcctct gccaactccg aaccataagt
    31501 cataatatct ataaaacggg aagagctgtt ttttgaaatt gtttcttatc actcagtgtt
    31561 aaacggtagg agaaaacctc ttttttattg atatttgatt ttcatcaaac agtcacatag
    31621 tcgattgctt ctgcttgcgg aatcgtttca tctacaaagt agactttata ccatgtcaag
    31681 aaactgaaga ttgtccagat ttttctttgc tcttctttac gtccttcgtg atggtcatct
    31741 agcaacttca tgattttttc ttgatcaaaa aattcttttg caaaatctgc ttcgaacaat
    31801 gctttgactt gttcgtagcc gtgttcttct ttcaaccaag ctttgattgg cacagggaat
    31861 cctaatttca cacgattcga ccatttttcc ggaagatgtt tgttcgcagc ttgtctgaaa
    31921 atatcttttg tgttgttttg attcaataaa aacttacttg gtatttgttg agccaatttc
    31981 atgacttcga tatccaataa aggtactcgg acttccaaag aacttgccat agaaagttta
    32041 tctgccttta acaagatatc ttttggcatc cattgatgaa gatcgacata ttgcatctta
    32101 ttgacttcat ctttgattcc ttctgttttc tcgtaatgaa cagtcatgat ttcatccaca
    32161 gatggtgctg tttgatattt tggtgttaac acttctgatg cttctgattc ttcgaacact
    32221 cgagcatgac cgataaaata ttcttttgca ggagcaagtg attcatataa atggatccgt
    32281 ccatggaaat ttttcatttt tccgatttta cgtcctaaat tatagcgtgt tccttttggt
    32341 aattttttca atccttgagc aatcacacgg atgaattttg aattcgtatg gaatccatac
    32401 gtttggtatc ccgcaaacag ttcatccgcc ccttctccag attggactac ccgcacactt
    32461 tgtgaagcaa gatttgctaa aaagtacaaa ggtacgcaag aaggatttga atcaggttca
    32521 tctaagtgat actggatcaa agggaatgct ttgaacgaca tgtctccgtc gatcactgct
    32581 gctgtattat ctaagtccaa tagttcggtt agttttctgg cttcaatcgc ttcattatag
    32641 gttttatcat caaacccgat tgagaaagaa tgatctggtt tcaatacaga ggttacataa
    32701 ctggaatcaa ccccgctgga taagaaagaa ccaacttcta catcactgac cgtatgtgct
    32761 tcaatagaag cttgaacggt ttcgtcgatt ttttcgatcc attcttgtcg ggaatgcgtt
    32821 tcttttgttt caaaatctgc atcccaatat tgctgaatgt ctatttttcc atctttatac
    32881 gtataataat ggccttcagg caaacgatag acatctttga agaatgtttc gccgtttaat
    32941 ggagaatatt ggaaagtcat ataaggtttc aacgcttctt tgttcaattc tttgttaaaa
    33001 tcaggatgag gcagaaaact tttgatttct gaaccaaaca taaatgttcc gttcatttct
    33061 gcataataat atggtttgat cccaaagtgg tctcttgcac cgaataactc attcttttca
    33121 ttatcccaaa tagcaaaagc aaacattccg cggatctttt gcaataattc tgttccccat
    33181 tcttcgtaac catgcaaaag gacttctgta tctgcatgtg tttgaaaaac gtggccagct
    33241 gcaatcaatt cttctctcaa aggctggtaa ttatagattt cgccattaaa aataatgatc
    33301 tttgtccgat cttcattgta aataggctga gtaccgccct ctaagtcaat aatacttaat
    33361 cttctgaatc ctaaagcaac atgtttatcg atatattctc ctgaactatt aggtccacgg
    33421 tgaacgattc gatccatcat tgtattaata attgtttttt tgttgtcctt gtcgttaaca
    33481 aaacctacaa taccgcacat ttaactttca catcctaata taaaattact gtttatttca
    33541 ttcatatgca tcttatcata gaataaatag cggacgaata ttttctctct tacaatttcg
    33601 tcacgtgaaa acaaaagatg aaagtttctg tttttacaga aaataaagtc ccaatatcta
    33661 atttaccatg ttttcttttt tgaggctacc ttattctctt cgtgttaaaa aaatattagt
    33721 ggatgctatt tccaaaaaaa ccagcaaaaa aagacacgac ctaaagatcg tgtctaatta
    33781 tgactgtatc agaaaatatg ataccaaacg gatctattca ttaattaatt gacatagttt
    33841 atctgttgct cttttatgac tggataactg accaattcat gacgatccaa gtcttcttta
    33901 ttcatattta cagcagtaat ttgactgtct tcatacgtac gataataata aatcccttta
    33961 tcaacgttac agcaagaaga ataaatcgta tattcgtatt ttctttctcc agtatcgcat
    34021 actccttttt gttgctcgac tgagcctagt atatgaaaaa attgactgat actttcagat
    34081 tctgaatcac ctgatgcagc attcatttta gtaaatgtgg cttttacaaa tcgagaaaca
    34141 gaagagagat ctccaggtaa gcccaatcct cccatcccac gactataaac attcaagctg
    34201 atctggtttg aaaaatgatt ttctggtgtt ccatttgata gcgagcgata attgttcaga
    34261 ttaaataatt gataatcaaa tggcggatta tttgtcaaca caccgacagg attatcatat
    34321 aaatgaagtc catctttcat actttcaatt actatcgatt tttctttatc agctaataac
    34381 cagtgtaaag gtgacaaggg tagtttttca ctaaaatcga tattgactag attgatagta
    34441 gccaataatt ctttagcttc gtctatggtt gagcattgcc ctagtatcca tggaataaac
    34501 tcaaatggtg caacgttatc ttttccttct tgtaattctt tataatcagc attgccagga
    34561 aaattcagtc ctgccatact caaccctttt tcatttgtag cctcataata gagtggatag
    34621 ttggataccc cagctgctat tcctatcatt gcataatgtt tatctaaatt ttttaccttt
    34681 ctaaaatcga aacgataatt tcttggagta atagtgacca cttcattata agacatctca
    34741 taatcaaaat tccttccaaa ataatggtct ttcgttgcat aagtgattgc ggtacacatc
    34801 gtttcccgtc ctaaaacaaa tcgtttttac acttttatct tacatctagt atttttttta
    34861 tcaaaaaaag gccaaagaag attgatttac tagcatttat aaaaaatagt actcaggggg
    34921 aatcaaaaaa tattgtaggt taaaagtaca acaataaggg gctgtgacaa aagtcttgtc
    34981 acagcccctt attccgaaca aacggtgttc aaaagcttgc atctgcggta ataagcccaa
    35041 tcaaacgaaa aaataggaaa agctattttt gtttggccgt tcttattact tgatgcagga
    35101 cagcttcttc acaacctcta atcgttgata taaggaaggt acaggatttg aacctgcgcg
    35161 ccggtattag ccggttcgcc ggatttcgag tccggtgcat taccactctg ccaaccttcc
    35221 gtaagtacta tttttaaact tttttcacga aatgtcaagc ctatttctaa tagataaata
    35281 acagaaatcg ctttttttag caaaaaagtc cattgacagt ttgcagccaa cggacttacc
    35341 gatcaaattc atactgatag aacactatct gattatttca ggattatcta atgctaaaat
    35401 cgagtcaatt gtccgtttga tcagtgcaat gatttgttct tctgttggat gcatgatgtt
    35461 tgatgacatc aatgacgcta agccagtcac tgctacccat gtaccagtat gcagagcatc
    35521 gacatattca tccgataatt gattgtatct ttcatcttct ttaactattt cacggaaata
    35581 attgtatgaa aaatcatgca ttttctttcc gtccccatgt tcatcaatgt acaatgccat
    35641 gtaaagacta tgatgctttt ttgcaaagta gatatagttc aaaccgagat caatgatttt
    35701 atcaccagta cgttcaatag ggaaaacatc ttcttttagt tgttcaaaga tagaatccag
    35761 caacgtattt tttaaatctt ccatgttttt gaattccaga taaatcggct gtgtcgaaat
    35821 ccccatcttt ttagcaatat ttctcgcagt aaatccttta aacccttcct ttgcaacaac
    35881 atcataagca gcttttagaa tttgatcctt ggtatagact tttcttctca ttaaaactcc
    35941 cccacttctt tactgcagta tatgttgttt tattgtaccc tatttttagc attttttgca
    36001 aacattttac tcaaaacgtt atattttaaa ttttttttca gtcttcttta actttttttt
    36061 gcaaaattaa aaaaatttgg ttaaattcaa tgggttccct tacattttta gttttgacct
    36121 aaatgatagt tgtccaaatc tttcatttca agttatagtt aaagaaaatg aaaaagaagg
    36181 tgtgtaatgg aaaacgaaac tgacgttatt tatattcatc ctcaaaaacg aatcgtttca
    36241 cagaaaagaa agtattttta tcttggtttt acaggtgttt ttttcttttt attggcttgc
    36301 tttctaatac tcctactgat aattggagtg gattgctaac tattcttacc tcgccaagca
    36361 atcttttgac agattatttt gctttaggcg gtttcggaag cgcattcata aatgtaggga
    36421 ttttgacctt actttctgtg cttttagctt atcggcacaa ggtgatttta aacggtccct
    36481 tatttgcttc gattctaaca gttaccggtt tctctttttt tggcaaaaac ctttataatt
    36541 ctatctcaat cattttaggt gtgtatctat acgctgtatt tgtcaataaa cctttttctc
    36601 agtacatcat gatcggactg tttggtagcg cattatcacc ggtcgttagt tatatcactt
    36661 ttggtatgcg ttttccttta ctgataggta ttttattggg gaatttagct ggcatagcaa
    36721 ttggtctact tcttccgccc ttagctgctc aaactttagt tttccatcgt ggattcacac
    36781 tttataatat tggattcacc tctgggttga ttgcgatgac ttttactgct gttttgaggt
    36841 tattcagcta ttcaatcgtc gaaaatacat tggttttcaa tgaatatcac tttcctctca
    36901 tttggattat ttttggcttt ttttcgctga cagtcggaat tggtttctat tataattcct
    36961 ttcggctttt ggggattcga gaaattttcg attcatctgg aaaattgaca actgatttca
    37021 ttgctaattc tggtattggt gctactttga tcaacatagg cttagttggt ctgatgctgt
    37081 cttcttatgt tttgctggtt ggcggtcagt taaatggacc tgtcatcggt gctattttat
    37141 ctgcggtggg tttcagtgct tttggttgtc atttaaaaaa cagttttccg atactagtcg
    37201 gaatatttat tgcttctttg tttggaactt ttcatgagat caccagtact ggcatgcttg
    37261 ttgcagctgt gtttgggaca ggtctcgcgc ccataagcgg tttttacggc agtttttacg
    37321 gtgtaatagc tggtgtacta catattgctc ttgtccataa cgtcagcact ttgcacggag
    37381 gactaaatct atataacagt ggtttttcaa ctggtttcgt tgcaggtatc cttgtaccga
    37441 tactagataa ctttaccgct gtcagaaagg aaaaaaagac acttggaaaa agaattatca
    37501 aaaagaatca tcgatgagct tcttacttat ttatattccc atgaaataac tgaaatacgt
    37561 attggagtag aatttgctga ggaagggctt ttcatagaga tacagggtac ggcagaaact
    37621 cagccagaag atttagatgt acttgctgat ttgctgaaca atcctcggga ccctagtatg
    37681 gaaatctatt atcaagaact attaggtaat ccccgacatg atcgggaaga ttatcatctg
    37741 ttaggtagtt tgattgatga cgtggaaatc atgtatgccc agccgattat caatattaag
    37801 atctttcgac gtgcttctca ttcctattat taaccctatt ttctatttat aaaagactga
    37861 atcaaaaaag cagctcctga aagttcgatt aaaatctact ttcaggagct gttcaagctt
    37921 gacattattg attttccaat ccttcataca cttcatctgt tacaggttct aaaaactctg
    37981 aattaccagc agtgatcgcc aaatgttcaa accaactgtc ttttgtcgca ccatgccaat
    38041 gtttaatccc tttgtgcgtt acgacgacat ctccagccat taatcgtctt gctggctttc
    38101 cttcttcctg ataccagcct tctcctccgg tcacaagtaa gatttgatag ccgtctttat
    38161 ggacatgcca gtgattgcga caacctggtt caaaagttac attacctaca ccaacagaaa
    38221 cttcgggatc attcactaac atattcagat agctttaccc ggtaaatact tgagcgtaag
    38281 cttcgttttt ttcacctgct ggaaaaatca cgccattgtg tatttcttcg tgttttgtcg
    38341 tcatttacgc ctctttctta tcttcgctat tttcttctaa atagatttct tttgctaaac
    38401 taaaagctga ccaagctttt ggccatccta cataaaaagc taaatgggta atgatttctg
    38461 ctatttcttc actagtaatg ccattttgct tgccaatctt cagatgagct ggcaattgtt
    38521 caaaatttcc tcctgaaatt aatgcagata tggtgatgat actacgctga tgagcagata
    38581 attcttctct ggaccatact tgtccaaata aaacatcatc attcaattct gcaaattttg
    38641 gtgcaaaatc tcctaattga tctcgtcctg cggtttgttt ttctgccatt tctcttattc
    38701 tcccttcacg actgttaggt gattcaacta tggttctaag gcaactttat tttctattgt
    38761 ttcttcgcat ttcattttaa atgtagtctt tcagcctgtc caatgcttag tttattcagt
    38821 cgatatgctt tttaagcata gttgctaacg cttttttt
//
LOCUS       DAXLPQ010000022        37660 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.022, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000022 DAXLPQ010000000
VERSION     DAXLPQ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.022"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            251..1033
                     /locus_tag="ACF3UO_001376"
     CDS             251..1033
                     /locus_tag="ACF3UO_001376"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3657414.1"
                     /translation="MVKKIDFHIHTVSSHKDYDFSYSPEWLKKYVRAAELDAIAITNH
                     DLFDESNFKQIQYDLPNTKVFPGIELSLEEGHVNIIFPEEDSPNLVHFSEWLSTQNLG
                     QNGKVSTEDFCTHMSNWENGIYIFELGKSNALSVPEKLESICSVGGVANQLKFQTFYR
                     IEDALTPVLFSDAHADDNDPEEKRKNIEILKNKNTYLQIDNCSFQEIKNCLMDKTKVG
                     INLRYLRDVIDIENHTVSTGLNLIVGKRGTENQFFRNDKKIL"
     gene            975..2291
                     /locus_tag="ACF3UO_001377"
     CDS             975..2291
                     /locus_tag="ACF3UO_001377"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3657415.1"
                     /translation="MLVNEVLKTNFLETIKKYYDYEDIYEIAQFETSNANDFIKKQRT
                     EQGKNALDIWKKRYDSQFSAIQDYLKNNEEDFNQDVEKFVESVKQFAKDSTTSNSTSK
                     YQLIKESNLEEISTKNLETHLYKLLDLINSPDLWELLSNSVEKRRVFVETYSEVRNLF
                     VQKQQNNKVREKVNDILGSVKKIVQSKTGITPVVDCEFSKIIQKHQIEKEINNFMQKI
                     VCNTEIKKEKIYGYQIIVKLSPFINATQFRKDRTSEAVQDDLIVPYKSGQYITFLRNL
                     KKRSFFNPSILEEYLLHLEVNLLDSDGVPASGGQAVGFALMMRLEEAKTKPIILIDEP
                     EASLDNEYIRKELRDAIRNLSASSTVFVVTHNSTLGALLEPDYLIVTTKDKEKGYRVL
                     TGEFSSHLISTKSDTTESSYEKFVEAMEAGIETYKKKGEIYESLNS"
     gene            2272..2556
                     /locus_tag="ACF3UO_001378"
     CDS             2272..2556
                     /locus_tag="ACF3UO_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657416.1"
                     /translation="MKVLIVNSGKSKFVIGENNVEPENLSRDDLLMILNNIYESEENV
                     VIPSIEELDEIRNPIEKEIVQQIIQKISDFSNNVENIRQEVQAQFPVIED"
     gene            2594..2917
                     /locus_tag="ACF3UO_001379"
     CDS             2594..2917
                     /locus_tag="ACF3UO_001379"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657417.1"
                     /translation="MVGIDNDSNFKSYEFEKTYDFSVEIPIVDEDTGEYTREIELVAG
                     QITFFGDADWDSTEKEYVYNFSWEESTRTFSHYGNAPDKEDEFIKDFKEYLLQQGVER
                     YNIGW"
     gene            2968..3192
                     /locus_tag="ACF3UO_001380"
     CDS             2968..3192
                     /locus_tag="ACF3UO_001380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_component: GO:0030127 - COPII vesicle coat [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0006888 - endoplasmic reticulum to Golgi
                     vesicle-mediated transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec23/Sec24 zinc finger-containing protein"
                     /protein_id="HFD3657418.1"
                     /translation="MTERFPDTDWWCDRCGAHLNSQNNFDDYKYTWKCTECGFKNSIS
                     KDNIYESHEEYYNTGDDDSGLLRSIFKKLF"
     gene            complement(3579..4199)
                     /locus_tag="ACF3UO_001381"
     CDS             complement(3579..4199)
                     /locus_tag="ACF3UO_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HFD3657419.1"
                     /translation="MATKVFISFRFSDGKEIKDELVDLFDESTEVINRSEDVDRSQMS
                     KDTIQEYLYEKLKDTSVTIVLLTPEAVSYRKNWIGNYDDWIYDELRYSLEDRNNNRAN
                     GVVAVYTDDAKDMILESSSHYCAHCQETKSCRTLKSFDNLARKNMLNIKQSYKKNPCN
                     DLYDDSHDSYISLVSLEEFKQDYTKYIDNAKDKRDRLHEFNIYKRM"
     gene            complement(4199..5611)
                     /locus_tag="ACF3UO_001382"
     CDS             complement(4199..5611)
                     /locus_tag="ACF3UO_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFD3657420.1"
                     /translation="MRQELFIKKFSKAIQEGNAAVFAGAGTSVDAGFVNWKNLVAPFA
                     NEIDLDIEKETDLVGLTQYYINKKRNRGSVNQEIIDQFSSQYAETEVMNLLTRLPIST
                     YWTTNYDKVIENGLKNNNRRGDIKRKTDDLAISIRDSDAIVYKMHGDVDSPNDAVISK
                     DDYERYSEKNSLFVTALRGDLVSKTFLFVGFGFEDPNLESILGKIKNLLGERTRDHYC
                     IQKKVLEQDYKNREEYSYAKIKQELKIEDLKRYGIDTVLVDDYSEIPKLILKIEEEYF
                     KNTIFISGSISDYNENWSQEKVNQFCYNLSRSLVSKNYKIISGFGLGVGSSVINGALD
                     EIYNTKYRHVSEHLGLFPFPQHDAGEKSLAKRWTENREQMISEAGICIFIFGNKLVNG
                     EVVLASGMMEEFRIAKERGKVIIPIGSTGFVAKEIFDEMKESGDYSYINDYWNDLENE
                     EDVIKVFNTINEIIEGVRFR"
     gene            complement(5641..6801)
                     /locus_tag="ACF3UO_001383"
     CDS             complement(5641..6801)
                     /locus_tag="ACF3UO_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFD3657421.1"
                     /translation="MGIVMRQYNNFYIKFQRQFKKAHGQVIETMPLEFSNKEYIERFK
                     YMFPDKILLIERERNYWYGKRIIRKNLSKIRCKGMSLETDSFILSTSKHIRKIKRESL
                     ASNEEMVKKVNTARTISLEKLKAESLRSKRKLNYIQEVEPPYLRNYRNRFFKTHDLHE
                     RLEIIRELSKYDSKEVREFFYAINGHIRNQSLKIEVQSYFQSLSLPFRLSRKKKGKKN
                     FIDNEIVKNKKGPDELKKRLYINDLEKIKRFDIFVSHNSRDEEKIIEFYKKFNKKGQV
                     VYIDWINDKYDLRREWCNASTVDIIKERIKQSDVFVLYFSGETLNSQWCTWELGYADA
                     LGKKICVYFSEDINRKGIPKFYVAYPELQMSKNIYVKIRGNEDILLKEWKKL"
     gene            complement(7207..8040)
                     /locus_tag="ACF3UO_001384"
     CDS             complement(7207..8040)
                     /locus_tag="ACF3UO_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3657422.1"
                     /translation="MKKLALLTLFSTALLVSAPLVSFADETASSSDVTILADDNPVVP
                     VEPTDPTTPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPSEPTEPSEPTEPS
                     EPTEPSEPTEPSEPTEPSEPTEPSEPTEPSEPTEPSEPTEPSKPTEPSKPTEPSEPTE
                     PSTPTEPSTPTEPSTPTVPNKPVDTNPIENPVNTDTGVVIVAVEDSKPIIQLANGTTK
                     KVEAKEIGANVQKDGTVTVKGSDGKMKVLPKTGDTENIALSVLGSLMVLGSAFIFKKR
                     I"
     gene            complement(8100..8468)
                     /locus_tag="ACF3UO_001385"
     CDS             complement(8100..8468)
                     /locus_tag="ACF3UO_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657423.1"
                     /translation="MGKINLNQIYTAKEMSERIGKNRNYLSQAYRNNKHEILKNFNYR
                     KIGGTIIFSDNPNNDLSQLITAKEASQLLGKNDEYFAHIYKRFPHRLEGIDHIYTGKT
                     LFLTKESLEAFKKKMNGNVR"
     gene            complement(8497..9465)
                     /locus_tag="ACF3UO_001386"
     CDS             complement(8497..9465)
                     /locus_tag="ACF3UO_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657424.1"
                     /translation="MSYYFEIRIILPEEEKQFLNRKLSKSELSEVTHYLQQKTSRGIP
                     VKFRVGIFRVEDQTKIMSVTLNTKNTKETDVINLLLNRVTDQHVLVYLNEPTEPTLNT
                     QELNRQELKTSNERQEIPQTEIPTETVNEPSVIKEISKKNQAKQTNSRKESLSESITK
                     KNVPKIHLFISILTLFIVLLIGISVIQQVQLQSVKKESELLKEQIERVKETDISQSKI
                     DTFGRYFLTYYFSQEKNQENYQSSLRTYVSEKVDIADWKALEKMLKSVNYYGSEQTKK
                     GYSVEYLLNVSVDNRSKMQKITFEVEPTKNGFLVTTQPKLTDFSFN"
     gene            9788..10975
                     /locus_tag="ACF3UO_001387"
     CDS             9788..10975
                     /locus_tag="ACF3UO_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFD3657425.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(11102..12034)
                     /locus_tag="ACF3UO_001388"
     CDS             complement(11102..12034)
                     /locus_tag="ACF3UO_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL family protein"
                     /protein_id="HFD3657426.1"
                     /translation="MDVIDQIKETGSDILSSAGDAISGIFEGVKESVDSVLHPIDSLL
                     GSWGSDLLEASMKIANKTTFDIPNIKLISTITNVFVFATTTFAICIVLYKVIEAQIQA
                     SNGSGDALTANIVQKLFYSSIALATLPWAMNFFIKKIVAPIGEYVIQQVANDLNVETI
                     GERLRNFLVSNFFNGGVSAVVLFVFVIFFAFSIAKYFVAICVFYADFLVLTMLTPLVA
                     LSLLTDEQNYFQIWIKELLSEALTMLIKLILYLLMITLMIAEKYTLPNFMLMVGCGLL
                     IIKTPSALQNMWYSTKVSKGGGLGNLAMMAMFRK"
     gene            complement(12036..12959)
                     /locus_tag="ACF3UO_001389"
     CDS             complement(12036..12959)
                     /locus_tag="ACF3UO_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657427.1"
                     /translation="MNGLKEFFGNIPMFQKQVEREIEEKGIKPSEGIKKMEFSRQVLR
                     NIVIGVLFIGILAFVGISYFNNKNQPPVAPTATTTSKESNQSEASGEATENSSQAVQG
                     SSDHLLKLSAKERADEATEAFESWYKSFSKGDVILEINKELLKEGSGGTSPIELQTKL
                     IDNLKAKFGDKVSDDFYSGLQASFNFNPVIVDGTKGLTISKQNDDQSQWLRTWFLDTE
                     KTAQNTKIILRNDFSYEWADWRNKGQHDEKVGSMFTQIDWANDLRYEVIGIVTSKQEK
                     NIENIGGVFVVMQYNEKIGKWQVSGTIGGVM"
     gene            complement(12977..14632)
                     /locus_tag="ACF3UO_001390"
     CDS             complement(12977..14632)
                     /locus_tag="ACF3UO_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFD3657428.1"
                     /translation="MSSLLAESDGLILGKFQSGNVVIQPEDSKISNRNIFVVGGPGSF
                     KTQSYVLPNVVNNRSTSIVVTDPKGEIYELTNEIKKAQGFKTVVINFKDFLLSSRYNP
                     LLYIRKSNDTNKIANVIVSAKNDPKRKDFWFNAQLNLLNTLIKYVYFEYEPSARTIEG
                     ILDFLEEFDPRYNEEGVSELDEQFERLPDGHEAKRSYYLGFRQAQSEARPNIVISLLT
                     TLQDFVDKEVAEFTSTNDFFFEELGTSKICLYVLISPLDRTWDGLVNLFFQQMFTELY
                     FLGDKHNAKLPVPLVMLLDEFVNLGYFPTYENFLATCRGYRISVSTILQSLPQGFELY
                     GDKKFKAIIGNHAIKICLGGVEETTAEYFSRQVNDTTIKVYTGGTSESKTSAKTTNRS
                     GSKSESYGYQKRRLITEGEVINLQQEENGRKSIVLIDGKPYMLRKTPQFELFGNLLKK
                     HEISQQDYISSQTEFAKEYIEELEVQHKQRKVQLASAPVFHEKKQENDLNKKEIKLPE
                     QPIESEVTEEVEEKEQLMSDILSSFDEGIEENTTNNDNSELPF"
     gene            complement(14625..15056)
                     /locus_tag="ACF3UO_001391"
     CDS             complement(14625..15056)
                     /locus_tag="ACF3UO_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657429.1"
                     /translation="MAKKKQEQVKLIILVILYLLLLPVTLIVFKLLPFIIANDTNIEL
                     STFVTTILKHPINTFLEIIQSNYMIPFFIVQIIVLIILFVFLHPTKRQPFEVVGKTNP
                     VHGSAYWGEESEINAPKNVHLIPEKSMKKILEKSMRRGKNE"
     gene            complement(15061..15612)
                     /locus_tag="ACF3UO_001392"
     CDS             complement(15061..15612)
                     /locus_tag="ACF3UO_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657430.1"
                     /translation="MEFDKIKVSLFISTLALLVVTIGMIVFGIKQGEQIRHLKSDLKS
                     VQTELADKQAEQNTNQSESEKIIKEFYKTVYNYEKSQKEISMTTVKELATDNVYQELQ
                     NEINVNNSYSPQQNTIQKSSVNENEIKILAYASKDNSQQYLVTAPIHQVFNGTKNDFE
                     INQIIQIKNQQITQRTTIQLGEE"
     gene            complement(15625..16734)
                     /locus_tag="ACF3UO_001393"
     CDS             complement(15625..16734)
                     /locus_tag="ACF3UO_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFD3657431.1"
                     /translation="MGATAAKLLIRYRKPIAKAILGFFVFIIVIFLLIFNNDQTAPSG
                     GLATENKNLSESVLRYKSTVEKYARQYDGMEYVPYILALMQIESGGNGGDPMQSSESL
                     GLPPNTIQDPERSIQRGVEFFVENMKSAINRGSDIKTALQAYNYGGGFVDFVVKNGGT
                     YSFELAKQFSINMSGGEKVPYVNALSTSMGYNYRYNYGNMFYVPKLLEYVNESQASAE
                     GVQNNSNNTGAVQVDVPSEYKNKLRYPRYDGHNYNTSGSYPFGQCTWYAFNRMAQIGK
                     PVDDFMGNGGEWGYKGKALGYKVTNKPKVGTAISFPPGSFGSDPVYGHVAFVEVVNAD
                     GTLLVSECNVVNPGSGTISYRVVPASIANIASYVE"
     gene            complement(16756..18108)
                     /locus_tag="ACF3UO_001394"
     CDS             complement(16756..18108)
                     /locus_tag="ACF3UO_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HFD3657432.1"
                     /translation="MKYKILKNLQFYYQENVIVVQINEKYLTNREHIFDVEESEQYFV
                     DVEEILTKDGKLEIVYHRPNGYTPLLDLKEYADFYKLDIVNRLLEMNVLEKTNTYLAM
                     QNILLKDTRDLLFIYKADHFGNLPYSTKEELEQWKNFICSFFGKFSLEKYEKNRIEIL
                     TKEKNSFLNDVEAVESLESLRDLIKNRLTEEQKNFFSAELQDKKANVRKIRRNKSLKI
                     ALVVGVIALYGGTVFLMKVNEKKQVTATQQSAETEITILNKIIDNDSENIEEDMQKLN
                     YPKKKQVDIYVKLGDYTKAYELDKKSDKKIIQSLYKQGETEKIENLDLPGSDYLADFK
                     KILAYDNSTDIEYLVQTSTDTTIVEALIDQAVKKKDIPTVKNIRQVSITQKKLAIDPK
                     RQISMIDLLIENNSEELENIYKDNSLNDDLKKKQTNDLLEENNTLLSEKIELTNAEKD
                     "
     gene            complement(18122..20083)
                     /locus_tag="ACF3UO_001395"
     CDS             complement(18122..20083)
                     /locus_tag="ACF3UO_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFD3657433.1"
                     /translation="MEKIPKEKIIVIPEVDTDVVSDLAPFNFTVERDKLLIDDSYAVP
                     YVITKYNNKPRGNWFNRIRKMSGDITISHYYTKANGNSLNDYYNRTIKNKQAEIDRSH
                     DPLTIIRLEREMKIAQTQLEQAVDENTSYLYLYTYVLIKSKSEDKLKKLCEDFETRCI
                     ASGVKALIPYTMIDKAYWSALPLQSNEVPEYTYTIANSISASSIFPFDDNELSVFTKN
                     MIIEGINKDTENIVSIDYTNRKLVVNRNKFVFGLSGGGKTTYLTSDYLKKYAFADNST
                     ELKHRIVLFDPEDEQTERVRSLGGEIINLSSMSDVRINPFQIYSRNTPDVDLKESLSD
                     FEEDELVENLEIKHKDFEMTENDIDKEISKRMNILTPYFLMVDHSLTDSQLSIIKLEA
                     KKCYTTLYEKKNLSKMENTDFPTFSDLESRLKALEETDPKRYKRIEDFIYSLEDFTIG
                     SRTIFNGHTNIDLSNPLICFSLRDLQTEEGIRDLAYLNSFSYLFEEITNNPQIVTSVY
                     ADEFHFLLKNKISADFFFQAYKRFRKYNADCTVSTQQIDDVLKAPDNIGKAIIGNSFT
                     KVFFGLDETEAQGISNELKLKLTKKELSFITSKRQGEALLFHGTKRAKIKVDLTQEEM
                     RLLNPGGYEDIYGVSPKKEINWLLRSKIQ"
     gene            complement(20094..20723)
                     /locus_tag="ACF3UO_001396"
     CDS             complement(20094..20723)
                     /locus_tag="ACF3UO_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657434.1"
                     /translation="MFDFLKKSSKSNDNKKSDTIKEMIYWEDSSRFQGVFKDFFVVYQ
                     PEKKQFSLVSMLKVDGLNVDTLPVSEQEGLNEDFGVFLSQNVLYEPQITSKNVPVEID
                     DFVEAWGNTVENYRKMPGHNEALLQLKASYYYHYRNLASNMETSKKQHFVINSEPISK
                     ETYDSLELSYQVLRDKTRTIRTALIAFLSKYDCQVEICTIGEMKKVLNS"
     gene            complement(20740..21123)
                     /locus_tag="ACF3UO_001397"
     CDS             complement(20740..21123)
                     /locus_tag="ACF3UO_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3657435.1"
                     /translation="MNSDQVKQALLDLLNADTEKGRTWFFPSNVSDRYTVILGLDLKQ
                     SAKAIGTALISVLLAILIFRSTAVFPLIIYVIVGLVSFGGVWAFYTIKPITDRPNISI
                     SDFMKQRKDFSKRPKVYYKKPKERV"
     gene            complement(21142..21474)
                     /locus_tag="ACF3UO_001398"
     CDS             complement(21142..21474)
                     /locus_tag="ACF3UO_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CagC family type IV secretion system protein"
                     /protein_id="HFD3657436.1"
                     /translation="MKKFIKDTKFKLGSAVVALGTLFITDPVFAATDPQAKLVQAGNT
                     IKGVLTALIVVVGGIACAKIVIKYLPSIDDPQEKNTMYKALGTALLVTALGGALVWLV
                     PWAYGLLA"
     gene            complement(21498..23483)
                     /gene="mobQ"
                     /locus_tag="ACF3UO_001399"
     CDS             complement(21498..23483)
                     /gene="mobQ"
                     /locus_tag="ACF3UO_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HFD3657437.1"
                     /translation="MAIFHLSMTIAKREGGKRSLIAMASYRSGEKLYSELYEKTNLYN
                     HRTVKPEAFILKPDYVPNEFLDRQTLWNKMELAEKQVNSQLCREVNVALPIELNNTDQ
                     RSLIEEFVKDNFVSEGMIADVAIHRDDENNPHAHIMLTMREVDSEGNILNKRKKIPKL
                     DENGNPILLENGKIKMVSIKTNDWDRKSLVSEIRKDWADKVNQYLKDRNIDQQITEKS
                     HAELGKKELPTIHEGFYSKKLEEKGVISELKRKNLEIQSYNDILAELDKLESQEKVLK
                     QDQNFTLKFEKTFSPLEKGELKNLSKEFKLFINDENIDKRLGELKRWENSLIFNNKME
                     IQKQRLMLSKISSERDMLTKANEILDKQAERFFKKSYPSLNIDKFSNHEVRAMVNETI
                     FRKQLLNKDQLAEVIYNERVVEKEESKKIFKEKPFQTSRYLDSKIKQVEDSITKENNP
                     ERKEILSIKKEKLIGIKQGLIEYVQSEVERKFDKNVSIDSVIEGEMLLAKADYYKTTD
                     FSKVEGVARFSSEEINSMLEQSKGFLTNIQTVKIPNDCQGVFFVQDSMKHIDELSPLA
                     KQNLKKVVNRNAYLPDSDKIELSKEIENTNKDQSQELDKDVPEKNEVTVKMFQFAKSI
                     NRLLSGNQLQKKRNLDKLIKQTKAKENQSLQRNIPLR"
     gene            23775..24074
                     /locus_tag="ACF3UO_001400"
     CDS             23775..24074
                     /locus_tag="ACF3UO_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657438.1"
                     /translation="MENQDQNINAINGNFNSKTKPKKRKKKTVSDIELQIKELQKKKE
                     ELILKSKADIGDFVLSTLSKLDISIESIEENKELFYDELETLLNANSQNFSELLK"
     gene            24077..24334
                     /locus_tag="ACF3UO_001401"
     CDS             24077..24334
                     /locus_tag="ACF3UO_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657439.1"
                     /translation="MANNDLNDINKRIEKLKIQKNILRANSEQNINRKRRTKRLIEKG
                     ALLEKYFEIDYLTVEETEEFLKIFSEYIKANKPKKYQKKEK"
     gene            complement(24357..24590)
                     /locus_tag="ACF3UO_001402"
     CDS             complement(24357..24590)
                     /locus_tag="ACF3UO_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657440.1"
                     /translation="MRGINNHQKYDFDLYQIEARSPMSTREITLTVDFIEKKVSGDII
                     AFGDWYDLDIESVNEILKQLKKEGQTLRTINFI"
     gene            24860..25252
                     /gene="merR"
                     /locus_tag="ACF3UO_001403"
     CDS             24860..25252
                     /gene="merR"
                     /locus_tag="ACF3UO_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFD3657441.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELSFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            25277..26917
                     /gene="merA"
                     /locus_tag="ACF3UO_001404"
     CDS             25277..26917
                     /gene="merA"
                     /locus_tag="ACF3UO_001404"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFD3657442.1"
                     /translation="MNKFKVNIQGMTCTGCEKHVESALEKIGAKNIESNFRRGEAVFE
                     LPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALINEDDYDLLIIGSGAAAFSSAIK
                     AIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFKGLQTSAGEVDL
                     ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGAKLSAKRFLIA
                     TGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEIT
                     LMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKKVYITVNGSKE
                     VIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGP
                     QFVYVAAYEGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVK
                     TSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDVIYAASLAVKFGL
                     TIEDLTETLAPYLTMAEGLKLAALTFDKDVSKLSCCAG"
     gene            27159..28481
                     /locus_tag="ACF3UO_001405"
     CDS             27159..28481
                     /locus_tag="ACF3UO_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3657443.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGRLCYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTLIKNLEKGDL"
     gene            28506..28769
                     /locus_tag="ACF3UO_001406"
                     /pseudo
     CDS             28506..28769
                     /locus_tag="ACF3UO_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043131.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(28816..29046)
                     /locus_tag="ACF3UO_001407"
     CDS             complement(28816..29046)
                     /locus_tag="ACF3UO_001407"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657444.1"
                     /translation="MNKVHVYNHNKFVKEINSDTNSIAKEIASQSPFAELKMTDEYDN
                     LILTTKGFFLDDVPNQIWLKNELMPALTNLQI"
     gene            complement(29316..29801)
                     /gene="vanZ-A"
                     /locus_tag="ACF3UO_001408"
     CDS             complement(29316..29801)
                     /gene="vanZ-A"
                     /locus_tag="ACF3UO_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFD3657445.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(29954..30844)
                     /locus_tag="ACF3UO_001409"
     CDS             complement(29954..30844)
                     /locus_tag="ACF3UO_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFD3657446.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            complement(31294..31902)
                     /locus_tag="ACF3UO_001410"
     CDS             complement(31294..31902)
                     /locus_tag="ACF3UO_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFD3657447.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(31908..32939)
                     /gene="vanA"
                     /locus_tag="ACF3UO_001411"
     CDS             complement(31908..32939)
                     /gene="vanA"
                     /locus_tag="ACF3UO_001411"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFD3657448.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(32932..33900)
                     /locus_tag="ACF3UO_001412"
     CDS             complement(32932..33900)
                     /locus_tag="ACF3UO_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFD3657449.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            complement(34115..35269)
                     /locus_tag="ACF3UO_001413"
     CDS             complement(34115..35269)
                     /locus_tag="ACF3UO_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFD3657450.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(35247..35942)
                     /gene="vanR-A"
                     /locus_tag="ACF3UO_001414"
     CDS             complement(35247..35942)
                     /gene="vanR-A"
                     /locus_tag="ACF3UO_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFD3657451.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            complement(36214..37527)
                     /locus_tag="ACF3UO_001415"
     CDS             complement(36214..37527)
                     /locus_tag="ACF3UO_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003141076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HFD3657452.1"
                     /translation="MATLHENRLLFNSNVTVSHSGGNLSSDSGLILAKEFMNKFEFSQ
                     ILCKNIQIQDDRLYHVHENESILEQIILQLIAGYPTDSSANILATDPIFQAVLSKKRL
                     ASQSSISRFWDRISTENIVQLQKVNQILIDKARTIRNTNEMIFDLDSTHSDTFGNQEM
                     TDYNAHYQTTGYHPLVAFDGLTGDFLKAELRSGNVYTSKGVAAFTRPLFEHYHSVTPV
                     STIMVRADSGFAMPDLYELCEEYDSLYTIRLKSNRNLYRIADQFITIKDHHDWSKKEV
                     HYYNATYQAKSWGKSRRICIKSTREASELLFRHEFIITNFSKDVSPEMVFQTYSKRGT
                     MENYIKEAKNGFYLDKTDSPRFIENHARMIVSLLAYNIVNFMRTLCFTNETKGYQVST
                     IRLFLFKIAGKIVHSGRRQYLKLSSYHVYQKLFYRILQNIQVLQC"
BASE COUNT        11453 a         6808 c         6214 g        13185 t
ORIGIN      
        1 tattattggg aatcccagct taaatcatag ataccgtaag ggattttatt ctttatttaa
       61 aactttgcaa cagaaccatt tcgaagatcc ttaatttaaa taaattagag gaggatttat
      121 attgccgcaa acaagttcta aaatcaatgt cactgagtgg ttgtttgtat ggcggatatc
      181 aagcatatta gtcagcgttt acatgatata atcaagacat gagtttccaa attattatgg
      241 aggtctacat atggttaaaa aaattgattt tcatatccac acggtttcta gtcataaaga
      301 ttatgatttt tcttattctc cagagtggct aaagaaatat gttcgagcag ctgaattaga
      361 cgcaattgct attactaatc acgatttatt tgatgaaagt aattttaaac agatccagta
      421 tgatttgcca aatactaagg tttttccagg tatagaactg agtcttgaag agggacatgt
      481 aaatattatt tttccagaag aagatagtcc taatctagtt catttttctg aatggctatc
      541 tacccaaaat ttaggacaga acggaaaagt atctactgaa gatttttgta ctcacatgag
      601 taattgggaa aatggaattt atatctttga actaggaaaa agtaacgcct tatcagtacc
      661 agaaaaattg gaatctattt gttctgttgg tggagtagca aatcaattga aatttcaaac
      721 tttttataga atagaagatg ctttaacacc agtattattt agtgatgcgc acgctgatga
      781 taatgatcct gaagaaaaaa ggaagaatat agaaatatta aaaaataaaa atacgtactt
      841 acaaattgac aattgctcgt ttcaagaaat aaagaattgt ttaatggata aaacaaaagt
      901 tggtataaac cttagatatt tgagggacgt aatcgatatt gaaaatcaca ctgtttcaac
      961 tggattaaat ttaattgttg gtaaacgagg tactgaaaac caatttttta gaaacgataa
     1021 aaaaatatta tgattatgaa gatatttatg agatagctca atttgaaaca tcaaatgcca
     1081 atgattttat aaaaaaacaa agaacagaac aagggaaaaa tgcgttagat atatggaaaa
     1141 aacggtatga ctcgcagttt tctgctattc aagactatct aaaaaataat gaagaagatt
     1201 ttaaccaaga cgtagaaaaa tttgttgaaa gtgtgaagca attcgccaaa gattcgacta
     1261 caagtaactc aacttccaaa tatcaactta ttaaagaatc gaatcttgaa gaaatttcca
     1321 caaaaaactt agaaacacac ttgtacaaat tacttgattt aattaatagt ccagatttat
     1381 gggagctgtt aagtaattca gttgaaaaaa ggagagtttt tgttgagaca tatagtgaag
     1441 taaggaattt gtttgttcag aaacaacaga ataacaaagt tcgagaaaaa gtaaatgaca
     1501 tactaggttc tgtaaaaaaa atagttcaat ctaaaactgg gattacccct gttgttgatt
     1561 gtgagttttc aaagataatt caaaaacatc agattgaaaa agaaattaat aatttcatgc
     1621 aaaaaatagt ctgtaatact gaaataaaaa aagaaaaaat ttatggatac caaattattg
     1681 tgaagctatc tccgtttata aatgctactc agtttagaaa agatcgtaca agtgaagcag
     1741 ttcaagatga tttaattgtt ccctataaaa gtgggcagta tattacattt ttaaggaatt
     1801 tgaaaaaaag aagtttcttt aatccttcta ttttagaaga atatctattg catttagaag
     1861 ttaacctgct ggattcagat ggtgtaccag catctggggg acaggctgtg ggatttgctc
     1921 taatgatgag attagaagaa gcaaaaacaa aaccaataat tttaatcgat gaacccgaag
     1981 cgtcacttga taatgaatac attcggaagg aattaagaga tgctataagg aatttgtctg
     2041 caagcagcac tgtttttgtg gttacacata attcaacatt aggagcatta ctggaaccag
     2101 attatctaat agtgactacg aaagataaag aaaagggata tcgcgtactt accggtgaat
     2161 tttcttctca tcttatctct acaaaatcag atacaactga aagtagctat gaaaaatttg
     2221 tagaagcaat ggaagcagga atagaaacat ataaaaagaa aggagaaata tatgaaagtc
     2281 ttaatagtta attcaggaaa atcaaagttt gttataggtg agaataatgt ggagccagaa
     2341 aacctttcta gagatgattt attaatgata ctaaataata tttatgaatc tgaagaaaac
     2401 gtggtgattc ctagtattga agagttagat gagattagaa atcccattga aaaagagatt
     2461 gttcaacaaa ttattcaaaa aatttcagat ttttcaaata acgttgaaaa tattcgccaa
     2521 gaagtgcaag cgcagtttcc tgttatagaa gattaaaatt tatatgctaa taaaaaataa
     2581 aggagtgagg aaaatggtag gaatagataa tgatagtaat ttcaagtcat atgaattcga
     2641 aaaaacatac gattttagcg tagagattcc aattgtagat gaagatacgg gggaatatac
     2701 tagagaaata gaattggtag ctggacaaat aacatttttt ggagatgcag actgggattc
     2761 aacagagaaa gaatatgttt ataatttttc ttgggaagag tctactagaa catttagtca
     2821 ttatggtaat gcacctgata aggaagatga gtttattaaa gatttcaaag agtatttatt
     2881 acaacaagga gttgagaggt ataatattgg atggtaaatg ttgaaattaa ttataaaaat
     2941 ttttaaatat gtagggagag atatactatg acagaaagat tcccagatac cgattggtgg
     3001 tgtgaccgtt gcggggcaca tctgaattct caaaataatt ttgatgacta taaatataca
     3061 tggaaatgta ctgagtgcgg ttttaaaaat agtatttcaa aagataatat atatgagagc
     3121 catgaggaat attacaatac aggtgatgat gattctggtt tactaagatc aatttttaag
     3181 aaattgtttt agtgctgaat tacttacaga ttttctgaga atgccttgaa acgttaatct
     3241 tccggtagtt aaaggagagg taatcacttt tctttttttt acttcattgt tccataactt
     3301 tatccaaggt gattaatttg acatagaact tgtgatggat ttatggacac gtgtttcaat
     3361 tcttttagag aaaaatcata ccaaaatagc agtgtccaga aatgaactat tttatggaca
     3421 tgagataaaa aagaaaaaca gccatttccg tttttctttt ttatctttgt gtctaaatat
     3481 ttgacattag tccaaacaaa agcactttat aaatcttgta cagaaaagtg ttgccttttc
     3541 atttattcta aagacaattt atgctaaatc aatgctcttc acattctttt atatatatta
     3601 aattcatgta gcctatctct tttatctttt gcattatcaa tatatttagt ataatcctgt
     3661 ttaaactcct ccaaacttac taaagaaata taagagtcat gactatcatc ataaagatca
     3721 ttacatggat ttttcttata gctttgcttt atattcaaca tattctttcg tgctaaattg
     3781 tcaaaagatt tcaaagttct acatgattta gtttcttgac aatgtgcaca atagtgtgaa
     3841 ctactttcta gtatcatatc tttagcatca tctgtatata ctgctactac gccatttgct
     3901 ctgttgttat ttctatcttc caaggagtat ctaagttcat cataaatcca atcatcgtaa
     3961 tttccaatcc aattctttct ataagaaacg gcctctggag ttaataatac aattgtaacc
     4021 gatgtatctt ttaacttctc atatagatat tcctgaatag tgtccttact catttgactt
     4081 ctatcaacat cttctgatct attaattacc tcagtagatt catcaaataa atcaactagt
     4141 tcatctttaa tctcttttcc atcactaaaa cgaaatgaaa taaatacttt tgttgccatt
     4201 atctaaatct aactccttca ataatttcat ttattgtatt aaaaactttt ataacatctt
     4261 cttcgttctc taaatcattc caataatcgt ttatatatga atagtcccct gactctttca
     4321 tttcatcaaa aatttctttt gcaacaaacc ccgtagaacc aattggaatt attacttttc
     4381 ctctttcttt agcaatccga aattcctcca tcattccaga tgcaagtact acctcaccat
     4441 taactaattt attaccaaat ataaaaatac agatcccagc ctcactgatc atttgttcac
     4501 gattttcagt ccaacgttta gctagagact tttccccagc atcatgttga ggaaaaggaa
     4561 ataatccaag atgctcactg acatgcctat acttagtgtt ataaatttca tcaagagctc
     4621 cattaataac actactacct actccaagtc caaaccctga tataatttta taattttttg
     4681 aaacaagtga acgcgataaa ttataacaga attgatttac cttttcttga ctccaatttt
     4741 cattgtaatc ggagatacta cctgaaataa aaattgtatt tttaaaatac tcttcctcta
     4801 tttttaatat caacttaggt atttcagaat aatcatcaac tagaactgta tctataccgt
     4861 accttttcaa atcttctatt tttaattctt gtttgatttt agcatagcta tattcctctc
     4921 gatttttata atcttgctct aataccttct tttgaataca ataatgatct ctagtacgct
     4981 ccccaagtaa attttttatc tttcccaaga tggattctaa attaggatct tcaaaaccaa
     5041 accccacaaa caaaaatgtt ttggaaacta agtcacctcg taaagctgtt acaaataggg
     5101 agtttttctc gctatatctt tcataatcat cttttgaaat aactgcatca ttaggtgaat
     5161 ctacatcacc gtgcatctta taaacaatcg catcgctatc acgaatactg attgctaaat
     5221 catctgtctt cctttttata tctcctctgc gattattatt ttttaagcca ttttcaatta
     5281 ccttatcata attagttgtc caatatgtag aaattggaag tcgtgttaac agattcataa
     5341 cttctgtttc tgcatattga ctagaaaatt ggtcaattat ttcttgattc accgaacctc
     5401 tatttctttt tttattgata taatattgag tcagtcctac aagatccgtt tctttttcaa
     5461 tatctaaatc aatttcattc gcaaacggtg ctacaaggtt tttccagtta acaaatcctg
     5521 catcgaccga tgttcctgca ccagcaaaca ctgctgcatt tccttcttgt atagctttcg
     5581 aaaatttttt tataaataat tcttgtctca tattaccctc atttctaatt tattataagc
     5641 ctataatttt ttccactctt taagtaaaat atcttcgttc cctctaattt tgacatatat
     5701 attttttgac atttgcaatt caggataagc tacatagaat tttggaatac cttttctatt
     5761 tatatcttct gagaagtaaa cacatatctt cttccctaat gcgtcagcat atcccaattc
     5821 ccaagtacac cattgggaat tcaaagtttc tcctgaaaag tataatacaa aaacatctga
     5881 ttgttttata cgctccttga taatatcaac tgtggaggca ttgcaccatt cacgccttaa
     5941 atcgtattta tcatttatcc aatctatata aactacctgt ccttttttat tgaacttttt
     6001 atagaactct ataatttttt cttcgtctct agaattatgc gatacgaata tatcaaatct
     6061 ttttatcttt tctaaatcat taatatataa tctctttttc aattcatctg gtcctttttt
     6121 attttttaca atttcgttat caataaaatt cttcttacct ttcttttttc tgctcaacct
     6181 aaaaggtaaa gataaactct gaaaatatga ttgaacttct atttttaatg attgatttct
     6241 aatatgccca tttattgcat agaaaaactc ccgaacttct tttgaatcat acttagaaag
     6301 ttctcttata atttccaatc gttcatgtaa atcatgagtt ttaaagaatc tatttcgata
     6361 attccttaaa tatggaggtt caacttcctg aatataattt aattttctct tgcttctcaa
     6421 ggactctgct tttaattttt ctaaagatat tgttcgggca gtatttactt tttttaccat
     6481 ctcttcgtta ctagctagac tctctctttt tatcttccta atatgttttg aagttgaaag
     6541 tataaaacta tcagtttcta aagacatacc tttacatcga attttggaaa gattctttct
     6601 aataatacgt tttccatacc aataatttct ttccctctct atcagcaata ttttatctgg
     6661 aaacatatat ttaaagcgtt ctatatattc tttattagaa aattctaatg gcattgtttc
     6721 tataacttgt ccatgagctt tcttaaactg tctttgaaat tttatataaa aattattata
     6781 ctgcctcatt acaatcccca tactcaataa gtccccccca ctacttaata ttattttgca
     6841 gtatattgtc ctctctgtct tttttctcaa tgttacacta aaatagattt tttggaaaac
     6901 tttgcaacag aacctatctc gttagttatc gcaccacttt tagtggttct aataatcaca
     6961 ttagttgatc attggttaga tgattagacg atggcaagca agttgctttc taactcacac
     7021 gcttgtattc gcaacaagtg aaaagaaaag ccgacctact agcaatatgt tattggtgtt
     7081 gcctagaacg attctaagcg cttgtttaat tttaaggtat acattcccct tcaaaacgtc
     7141 ctagaatgat tcaataaaag catggctgct agtgaaactt gcgaccacgc ttttataaat
     7201 acttaattag attcgctttt taaaaatgaa tgctgatcct aataccatta atgaccctag
     7261 gacagacaat gcaatatttt ctgtgtctcc tgtttttggt aaaactttca tttttccgtc
     7321 tgaaccttta accgttactg ttccgtcttt ttgaacgttt gcaccaattt ctttagcttc
     7381 aactttcttt gttgttccgt ttgctaattg aataatcggt ttactatctt caactgcaac
     7441 aatcacaacg cctgtatctg tattaactgg gttttcgatt gggtttgtgt ctactggttt
     7501 gtttggtact gttggtgtac ttggttccgt tggtgtactt ggttccgttg gtgtacttgg
     7561 ttctgttggt tcgcttggtt ctgttggttt gcttggttct gttggtttgc ttggctctgt
     7621 tggttcgctt ggctctgttg gttcgcttgg ctctgttggt tcgcttggct ctgttggttc
     7681 gcttggctct gttggttcgc ttggctctgt tggttcgctt ggctctgttg gttcgcttgg
     7741 ctctgttggt tcgcttggct ctgttggttc gcttggatcg actggatcga ctggatcaac
     7801 tggatcgact ggatcaactg gatcaactgg atcaactgga tcgactggat cgactggatc
     7861 aactggatca actggatcaa ctggagtagt cgggtctgtc ggttctactg gaacgactgg
     7921 attatcatcg gctaagatag taacatcact gctacttgcg gtttcgtctg caaaactgac
     7981 aagcggtgct gatactaata atgcagtgct gaatagtgtt aagagggcta attttttcat
     8041 tttataatct ccttaaaaat tagtatttgt gtacataaat agtatatcat aaatatgctt
     8101 tatctgacat ttccattcat ctttttttta aaagcttcta gcgattcttt cgttaagaat
     8161 aatgttttac ctgtataaat gtgatcgatt ccctctagtc tatgaggaaa ccgtttataa
     8221 atgtgggcaa agtattcatc attctttcct aacaactgac ttgcttcttt tgctgtaatc
     8281 aattgcgata aatcattatt gggattatca gagaaaataa ttgttccacc aatttttcga
     8341 taattaaaat ttttaagtat ttcatgtttg ttgttacggt aagcttggga taggtaattt
     8401 ctattcttac ctatccgttc actcatttct tttgctgtgt aaatttgatt taaattaatt
     8461 tttcccattg tttaagcact ctctttttag cgtatttcag ttaaaagaga agtctgtaag
     8521 ttttggttga gttgtcacaa gaaagccgtt tttagttggt tcaacctcaa aagtgatttt
     8581 ttgcatttta ctacgattgt ctactgaaac atttagaagg tattcaacgc tatacccttt
     8641 ttttgtttgt tcactaccat agtaattgac actcttaagc attttctcta acgctttcca
     8701 atcagctata tctacctttt cggatacata tgttcttaaa cttgactgat aattttcttg
     8761 atttttttcc tgtgaaaaat agtaagtcaa aaagtatctt ccaaaagtat ctattttcga
     8821 ttgagaaata tccgtttctt tgacacgttc aatttgttct ttcaataatt cgctctcttt
     8881 tttgactgat tgaagttgta cttgttgaat aacacttatt cctatcaata atacaataaa
     8941 aagagtcaaa atagatatga acaaatgaat tttgggaaca tttttcttgg ttatggattc
     9001 tgatagtgat tcttttctac tattcgtttg ttttgcttgg ttctttttcg atatttcctt
     9061 aataacacta ggttcattta ctgtttcagt tggaatttct gtctgcggta tttcttggcg
     9121 ttcattactc gtttttaact cctgacgatt taattcttgc gtattaagcg ttggttctgt
     9181 tggttcattc aagtaaacta aaacgtgttg atctgttact cgatttaata acaagttaat
     9241 tacgtccgtt tctttggtat tttttgtatt cagcgtaaca gacataattt ttgtttgatc
     9301 ttctactcta aaaataccta cacgaaattt aactggaatt cctcgacttg tcttttgttg
     9361 taaatagtgt gtgacttcgg ataattcgct tttacttaat tttcgattca aaaattgttt
     9421 ttcttcttcg ggaagaataa ttcgtatttc aaaataataa gacaatcgtt atcccccttg
     9481 tatattagag ttagggtttt aaccttccgg ttttgattgg ataaccctat gaaccatcgt
     9541 tattttaatt tggtattaac tcatttcttt tgagataata tatttattgg attgagaggc
     9601 taagccgttc cccccttggg tcattgaacc cgcactcgag agactggctc ctctctctga
     9661 taagtggatt gcgtatgagt tagatgttga aagtccttac tttactccgt atctcgtaca
     9721 aggtagtgac gcttttcagt tgagtggatt tcaatccaaa attctttttt tgaaaggtca
     9781 gatatacatg tactttttag gcattgatat cggtaaacgc actcacgttg cttctatcat
     9841 gaacgaggaa ggaaaggtat tactaaaagg tttttcattt cctaacacca ctgaaggagc
     9901 agagtcatta attgagcgaa tggtcgacta ttccggagca cccagtgact ttgttatagg
     9961 gatggaagcc acggggcact attggctgtc catcttttca taccttcacg aatcagatta
    10021 tttgattcac gttgtgaatc cccttcaaac agacggatgg cgtaaaggta cagaaatacg
    10081 gaaacgaaaa aacgatatta ttgattctgt tttgattgct gacttaatgc gctatggctc
    10141 atttgtcgaa acggtcttat ccgatgaaaa tgttttttct ttgaaacaac tttctcgtta
    10201 ccgaacttat ttagtaggta cagcgagcga cttcaaaaga aaaattatag ccgtattgga
    10261 tcaagtcttt ccagaatacg cgacgatttt taccaagcag ggcgttttcg gaaaagcttc
    10321 taaagagtta ttgctggcgt ttagtgcccc gatcgactta gaaaacattt cctcagaaac
    10381 tttggcccaa tacttagctg agttaagcag gaaccgaatc aaggcagaaa aagcggacca
    10441 attgaagcaa gcagcttcta actcctttgg agtaaaattt gctcaagaag cgttcacctt
    10501 ccaactacgt tcaatgattg aacaattaaa attcattgaa agccaaataa aggaaacgga
    10561 aagagaaatc aagcacataa tggacacttt aaattctgtt attctcacaa ttcctggaat
    10621 tggtcctata aacggtgcga ctattcttgg tgagatcgga gatattcaaa aattttctaa
    10681 cccgaaaaaa ctcgttgctt acgctgggat agacgcttcc gtgacacaat cagggcaata
    10741 tgaggcaacg cataatgtta tgagtaaacg agggtctcca tatttgcgaa aagccttgtt
    10801 ttcggcggct ttagtagctt ctcaatgtga tcctgttttt agtgcgtttt accagaaaaa
    10861 agtttccgaa ggaaaacatc atctaactgc cttaggtgcg gtttctcgta agctttgtta
    10921 cgtgattcat gctattttga ctaaaaacga gccttatata attgtttctg attagctatt
    10981 gaacattcaa aaaaactaat ggtaagaagc ttatttgttg tacccttttt tcggaattat
    11041 ctgttataaa atattttttg atttggctaa tttttacttg actctatata gttagtctct
    11101 cttattttct aaacatagcc atcattgcta agtttccaag tccgccacct tttgacactt
    11161 tggttgaata ccacatattt tgtagggctg acggtgtttt gataatcaac aagccacaac
    11221 caaccattaa cataaagttt ggtaacgtgt atttttcagc aatcatgagt gtaatcatga
    11281 gtaagtacaa aataagctta ataagcattg tgagtgcttc ggataacagt tctttgatcc
    11341 atatttgaaa gtaattttgt tcgtctgtta aaagcgataa ggcaactaat ggtgttaaca
    11401 tagtcagtac caagaaatcg gcataaaaga cacagatcgc tacaaaatac ttggcaatgg
    11461 aaaaggcaaa gaatatcacg aaaacaaaga gaacaacggc gctaacgcca ccattaaaga
    11521 aatttgatac taagaaatta cgcaatcgtt cgccgatcgt ttccacattc aaatcattag
    11581 cgacttgttg aatcacatat tccccgattg gtgcaacaat ctttttgata aaaaagttca
    11641 ttgcccaggg caacgttgct aaggcaatag acgagtaaaa cagcttttga acaatattag
    11701 cggtcaatgc gtcaccactc ccattagaag cttgtatttg cgcttcaatg accttataca
    11761 acacaataca aattgcaaag gtcgtagtgg caaagacaaa cacgttggta atggtgctaa
    11821 ttaattttat atttggaata tcaaaagttg tcttattcgc aattttcatg cttgcttcta
    11881 aaaggtcgct tccccaactg cctaataaac tatcgatcgg gtgcaaaaca ctatctacac
    11941 tctcttttac gccttcaaat attcctgata tggcatcacc ggcagaactt aaaatgtctg
    12001 atccggtttc ttttatttgg tcaattacgt ccatattaca ttacaccacc aatcgttccg
    12061 ctaacttgcc actttccaat tttttcgttg tattgcataa ctacaaatac tccaccaata
    12121 ttttctatat ttttttcttg tttgctggtt actatcccta taacttcata tcttaaatca
    12181 ttagcccaat caatttgtgt aaacattgat cctactttct catcatgttg tcctttgttt
    12241 ctccaatctg cccactcata agaaaaatca ttgcgtagga taattttggt attttgcgct
    12301 gttttttcag tgtctaagaa ccaagtccgt aaccattggc tttgatcgtc attttgcttg
    12361 gaaatcgtta gcccttttgt accgtcaacg attactggat tgaaattaaa gcttgcttgt
    12421 aaacctgaat agaaatcatc tgaaacttta tcgccaaact tggcttttaa gttatcaatg
    12481 agttttgttt gtaactcaat cgggcttgtt ccgcctgatc cttctttcaa taactctttg
    12541 ttgatctcta aaatcacgtc accttttgaa aatgacttgt accaactctc aaaagcttct
    12601 gtcgcttcgt ctgctcgttc tttggcactt aatttgagta aatggtcgct tgacccttga
    12661 acggcttgtg agctgttttc tgtagcttct ccgcttgctt ccgattggtt actttctttg
    12721 cttgtggtgg tggcggttgg tgctactggt ggttgattct tattgttaaa ataagaaata
    12781 ccaacaaagg caagaatgcc aataaacaag acaccaatca ctatgtttct aagcacttga
    12841 cggctaaatt ccattttttt aataccctcg ctaggtttaa tccctttttc ttcgatttct
    12901 cgctcaactt gtttttgaaa cattgggata ttcccaaaaa attctttcaa tccattcatt
    12961 tgatttcctc cgatctttaa aatggtaatt cgctgttgtc attgttggtt gtgttttcct
    13021 ctataccttc atcaaaacta cttagaatat cactcattaa ttgttctttt tcttctactt
    13081 cttctgttac ttctgattcg atcggttgtt caggtaattt gatttctttt ttatttaagt
    13141 cattttcttg tttcttctca tgaaaaactg gggcgcttgc gagttgtact tttctttgct
    13201 tgtgctgtac ttccaattct tcaatgtatt ctttggcaaa ttctgtttga ctgcttatat
    13261 aatcttgttg tgaaatttca tgctttttaa gaagatttcc gaacaattca aattgtggcg
    13321 tttttcttaa catgtaaggt ttaccgtcaa ttaacacaat actttttctt ccattttctt
    13381 cttgttgtaa attgataact tccccttcgg taattaatcg ccttttttgg taaccgtagc
    13441 tttctgactt acttccgctt cggttagttg tttttgcgga cgttttactt tcacttgttc
    13501 cgcctgtata taccttgatt gttgtatcat ttacttgtct tgaaaagtat tcagcggttg
    13561 tttcctctac accacctaga caaattttaa tggcatgatt cccaatgatc gctttaaatt
    13621 tcttatctcc gtatagttca aagccttggg gcaatgactg taaaatggta ctaactgaaa
    13681 tacgataccc tcgacatgtt gcaagaaaat tctcgtatgt tggaaagtag cccaaattga
    13741 caaattcatc tagtaacata actaaaggta ctggcaattt tgcgttgtgc ttatccccta
    13801 aaaaatataa ctctgtaaac atttgttgga aaaagagatt cactaagccg tcccaagttc
    13861 gatctaatgg ggaaattagc acgtataaac aaatttttga cgttcctaat tcctcaaaga
    13921 aaaaatcgtt tgtactggta aattctgcta cttctttatc aacaaaatct tgtaaagtcg
    13981 tcaatagact aataacaatg tttggtcttg cttcactttg tgcttgtcgg aagcctaaat
    14041 agtaactgcg ttttgcttcg tgtccgtctg gcaaacgctc aaattgttca tcaagttctg
    14101 atacaccttc ttcgttatag cgtggatcaa attcttctaa aaagtctaaa ataccctcaa
    14161 ttgttcttgc gcttggttca tattcaaaat aaacatattt aatcagtgta tttaataagt
    14221 ttaattgtgc attgaaccaa aaatctttcc gtttgggatc attctttgct gatactatga
    14281 cgttcgcaat cttgtttgta tcatttgatt tgcgaatgta aagtaatgga ttgtacctag
    14341 aacttagtag aaaatcttta aaatttatga caaccgtttt gaagccctgg gcttttttta
    14401 tttcattggt taactcgtaa atttcccctt ttggatcggt tacaacaatt gacgtactgc
    14461 gattatttac aacattaggc aaaacataac tttgtgtttt aaatgatcct ggaccaccta
    14521 ctacaaaaat atttcgattg cttattttgc tatcttcggg ttggatcaca acatttccgc
    14581 tttgaaattt ccctaagatt aaaccgtctg attctgctaa caaactactc atttttcccc
    14641 ctcctcattg acttttctaa tatctttttc attgactttt cagggatcaa atgaacattt
    14701 tttggtgcgt ttatttctga ttcttccccc caataagccg atccatgaac agggtttgtt
    14761 ttcccgacaa cctcaaacgg ttggcgtttg gtagggtgaa gaaagacaaa taaaataatt
    14821 aaaacaatga tttgtacaat gaagaacgga atcatgtaat tagattgaat gatctctaaa
    14881 aaagtattga tcgggtgctt taaaatagtt gtaacaaagg tactcaattc aatatttgta
    14941 tcattcgcaa tgataaaagg taataattta aacacaatca atgttactgg taataatagt
    15001 agatagagta taactaggat aatcagtttt acttgctctt gctttttctt cgccatgctt
    15061 ctactcctct cctaattgaa tggtcgttct ttgagtaatt tgttggtttt taatttggat
    15121 aatttggttt atttcaaaat cattttttgt accgttaaaa acctggtgaa tcggtgctgt
    15181 tactagatat tgctgtgaat tatccttact tgcataagca agaattttta tttcattttc
    15241 gtttactgaa gacttttgaa tcgtgttttg ttgtgggcta tatgaattgt ttacgttgat
    15301 ctcgttttgt aattcttgat aaacgttgtc tgtcgctaat tctttaaccg ttgtcataga
    15361 tatttctttt tggctttttt cgtagttata aacggtcttg taaaattctt tgataatttt
    15421 ttccgattcg ctttggttag tgttttgttc cgcttgtttg tctgctagtt ccgtctgtac
    15481 gctttttaaa tcacttttta agtgacggat ctgttcgcct tgctttattc caaaaacaat
    15541 catgcctatg gtaaccacaa gtaaagcaag cgttgagata aacaaactaa cttttatttt
    15601 gtcaaactcc atttttttct ctccttattc aacataactt gcaatgtttg caatagaagc
    15661 tggcactact cgataactga ttgttccact tcctgggttt actacattac actctgatac
    15721 aagaagcgta ccgtctgcat ttacgacttc tacaaaggca acgtgtccgt aaactggatc
    15781 agaaccgaaa gaacctggag ggaaagaaat tgccgtacct actttgggct tatttgttac
    15841 tttatagcct aaagctttcc ctttatagcc ccattcgcca ccattgccca taaaatcatc
    15901 aactggtttt cctatttgag ccatacgatt aaaagcgtac caagtacatt gcccaaatgg
    15961 ataactaccg cttgtgttat agttgtgtcc gtcatatctt ggataacgta atttattttt
    16021 gtactcacta ggtacatcaa cttgaacagc gccagtatta ttagaattgt tttgaacgcc
    16081 ctctgcgctt gcctggcttt cgttaacgta ttcaagtaat tttggcacat agaacatatt
    16141 tccgtagtta tagcggtaat tgtagcccat tgaagtagat aaagcattta cataaggtac
    16201 cttttcgcca cctgacatat taatagaaaa ttgtttagcc aactcaaaag aatacgttcc
    16261 gccattcttc actacaaaat caacaaaacc accgccataa ttgtacgctt gaagagctgt
    16321 ttttatatct gatcctcggt ttatagcgct tttcatattt tctacaaaaa actctactcc
    16381 tcgttgtatg cttcgttcgg ggtcttgaat ggtgttaggg ggcaatccta aactttcgct
    16441 tgattgcata ggatcgccac cattcccgcc cgattcaatt tgcatgagtg ctaagatata
    16501 aggtacatat tccataccgt catattgtct agcgtacttt tcaacggtac ttttgtacct
    16561 caaaacagat tcacttaaat ttttgttttc tgttgctagt ccgccactag gggcggtttg
    16621 atcgttatta aaaataagaa ggaagattac aatgataaag acgaaaaagc ctaaaattgc
    16681 tttcgctatc ggttttcgat aacgaataag cagtttagca gctgttgctc ccatgatatg
    16741 aaatcaccaa ccttcctaat ctttttcagc gtttgttaat tcaatctttt cactaagcaa
    16801 tgtgttgttt tcttctaaca agtcattggt ttgttttttc ttcaagtcgt catttaaaga
    16861 attatcctta tatatatttt ctagttcttc actgttattt tcaatcaata agtcaatcat
    16921 gctgatttga cgtttaggat cgattgctaa tttcttttgt gtaattgata cttgacgaat
    16981 attttttact gttggaatat cctttttctt taccgcttga tcgattaaag cttcaacaat
    17041 tgttgtatcg gtacttgtct gaaccaggta ctcaatatct gttgaattgt catacgctaa
    17101 aatctttttg aagtctgcta aatagtcgct tcctggcaaa tcaagatttt ctattttttc
    17161 ggtttcccct tgtttgtaca gactttgaat aattttttta tctgactttt tatcaagttc
    17221 ataagcctta gtgtagtcac caagtttcac gtaaatatca acttgttttt tcttaggata
    17281 gttgagtttt tgcatatctt cttcgatatt ctcactatca ttatcaataa tcttatttaa
    17341 aatagtgatc tctgtttctg cgctttgctg tgtagccgta acttgttttt tctcatttac
    17401 tttcataaga aaaaccgtac cgccatataa cgcaataaca cctacaacta acgcaatttt
    17461 taagctttta tttctgcgaa tttttcggac gtttgctttc ttatcctgta attcagcaga
    17521 aaagaaattc ttttgttctt cggttagtcg attttttatt aaatctctta atgattccaa
    17581 actttcaact gcttctacat catttaaaaa tgaatttttt tcttttgtta gaatctcaat
    17641 acgattcttc tcatactttt caagcgaaaa tttaccaaaa aaactacaaa taaaattttt
    17701 ccactgctct aattcttctt tagttgagta aggcaaatta ccaaaatgat ctgctttata
    17761 aataaaaagc aagtcacgtg tatctttgag taggatattt tgcattgcta gataggtgtt
    17821 tgttttttct agtacattca tttcaagtaa tcgattcact atatccaatt tataaaaatc
    17881 agcatattct tttaaatcaa gtagtggtgt atagccatta ggacggtgat aaacaatttc
    17941 tagttttccg tctttggtta aaatttcctc gacatcaaca aaatattgtt cactttcttc
    18001 tacatcaaaa atatgttctc gattcgtcaa atatttttcg tttatttgga cgacaatgac
    18061 attctcttga tagtagaatt gtaaattttt caagattttg tatttcattt ttttctccct
    18121 tctattgaat tttcgatctt aacaaccaat tgatctcttt cttcggacta acgccgtaaa
    18181 tatcttcata tccgcctggg ttaagcaaac gcatttcttc ctgggtcaaa tcgactttaa
    18241 ttttagccct ctttgttcca tgaaagagta aagcttcccc ttgacgtttt gaggtaatga
    18301 aagataattc tttttttgta agtttaagtt tcaactcgtt tgagatacct tgcgcttccg
    18361 tttcatcaag tccaaagaac acttttgtaa agctattccc aataattgct ttaccgatat
    18421 tatcaggtgc ttttaataca tcatcaatct gttgggttga tacggtacaa tcggcgttat
    18481 attttctaaa gcgtttgtaa gcctggaaga aaaaatctgc actaatttta tttttcagta
    18541 aaaagtgaaa ttcatctgca taaacagacg ttacaatttg cggattgttg gttatttctt
    18601 caaatagata actaaagctg ttgaggtatg ctaaatctct gattccttct tcggtctgta
    18661 aatctcgcaa agagaagcaa attaacggat tgcttaagtc aatatttgta tgaccgttaa
    18721 atatggtacg gcttccgatt gtaaaatctt ctaatgaata aataaaatct tcaattcgct
    18781 tgtatcgttt gggatcagtt tcttctaatg ctttcaatcg actttctaag tctgaaaatg
    18841 ttggaaaatc ggtgttttcc atttttgaca agtttttctt ttcgtataaa gtggtatagc
    18901 attttttcgc ttctaactta ataatagata attgactgtc agtcaaagag tgatccacca
    18961 ttaggaaata tggcgttaaa atattcattc gtttactgat ttctttatca atatcatttt
    19021 cagtcatttc aaaatctttg tgctttattt caagattttc tacaagttcg tcctcttcaa
    19081 aatcggataa cgattctttt aaatccacat ctggtgtatt gcgtgagtag atttgaaacg
    19141 gattgatacg aacatctgac atagacgaaa gattgattat ttcgccccct agagaacgta
    19201 cacgttctgt ttgttcatct tcgggatcaa ataaaacaat tctgtgtttt agttctgttg
    19261 agttatcagc aaaagcatat tttttcaaat agtctgacgt taggtaagtg gtttttcccc
    19321 caccagataa accaaaaacg aatttattac gattgactac taattttctg ttggtgtaat
    19381 caatactaac gatattttca gtatctttat taattccctc aataatcata tttttagtaa
    19441 atacacttaa ttcattatca tcaaaaggaa aaatactgct tgcactgatt gaattagcga
    19501 ttgtgtacgt gtattcaggc acttcattag attgtaaagg taaggcactc caatacgctt
    19561 tatcaatcat agtatatgga atcaaggctt ttactccact tgcgatacaa cgtgtttcaa
    19621 aatcttcaca caattttttc agtttatctt cggacttact tttgatcaaa acataggtat
    19681 ataaataaag ataagaagtg ttttcgtcaa cggcttgttc taactgcgtt tgtgcaattt
    19741 tcatttcacg ttctaaacgg ataatcgtca acggatcatg cgaacgatcg atctctgctt
    19801 gcttgttctt aatggttctg ttgtaataat cattcaatga gttaccgttt gctttagtgt
    19861 aataatgaga tatggttata tctccactca ttttacgaat acgattaaac caatttcctc
    19921 ttggtttatt attgtatttt gtaatgacat agggaactgc gtatgaatca tcaatcaata
    19981 atttgtcacg ttctactgta aagttaaatg gtgctaaatc agatacaacg tccgtatcaa
    20041 cttcgggtat tacaataatt ttctcttttg gtatcttctc cattttaacg ctcctaacta
    20101 ttcaaaacct ttttcatctc gccaatcgta caaatttcaa cctgacaatc atatttactt
    20161 aaaaatgcaa ttaaagctgt tctgattgtt cttgtcttat cacgtaacac ttgataagac
    20221 aattccaaac tgtcgtatgt ttcctttgaa attggttcag aattaattac aaaatgttgt
    20281 ttctttgaag tttccatgtt acttgctaaa tttctgtaat ggtaataata gctagctttt
    20341 agttgtaata aagcttcgtt atgccctggc attttgcgat aattttctac tgtattcccc
    20401 caggcttcta caaaatcgtc aatttctact ggtacattct tagaagtgat ctgcggttca
    20461 tatagaacgt tttgagatag aaagacacca aaatcttcgt ttaacccttc ttgctctgat
    20521 actggcaatg tatcaacgtt taagccgtca acttttagca tactcacaag gctaaattgc
    20581 tttttttctg gctgataaac gacaaaaaag tctttaaaaa cgccttgaaa tcgggaacta
    20641 tcttcccaat aaatcatttc ttttatcgta tcgctttttt tattatcgtt acttttggaa
    20701 ctttttttta gaaaatcaaa caatgaaatc acctctcttt tacactcgtt cttttggctt
    20761 tttgtaatag acttttggtc ttttagaaaa gtcttttctt tgcttcataa aatcagatat
    20821 agaaatgtta ggtcggtctg taattggttt aatcgtataa aacgcccata caccaccaaa
    20881 tgacaccaaa ccaacaatga catagataat taaaggaaaa acggctgtgc tacggaaaat
    20941 aagaattgcc aatagcacgc ttattaatgc cgtaccgatc gcttttgctg attgttttaa
    21001 atctagccct aaaatgactg tgtaccgatc agatacattg gacggaaaaa accaagtccg
    21061 ccctttttca gtgtctgcat ttaacaaatc taatagggct tgtttcactt gatcgctatt
    21121 cataactaac tcccttctct attaagcaag taagccatac gcccaaggta ctaaccaaac
    21181 caacgcccca cctaatgccg taacaagcaa ggctgttccc aaggctttat acatggtatt
    21241 tttttcttgt gggtcatcaa tagacggcaa gtatttaata acaatcttcg cacaagcaat
    21301 cccaccaact acaacaatta aggctgttaa aacacctttt atagtgttac ccgcttgaac
    21361 taatttcgct tgtggatcag tggctgcaaa cactggatca gtaataaaca atgtacccaa
    21421 cgcaacaacc gcacttccaa gcttaaactt tgtatctttg ataaattttt tcattttata
    21481 cacctcttgt ttttatttta tcgcaaagga atattccttt gtaatgattg attttctttt
    21541 gcttttgttt gcttaatcaa tttgtctagg tttcgttttt tctgtagttg gttaccactc
    21601 aacaaacgat taattgactt cgcaaattgg aacattttta cagtcacttc atttttttct
    21661 ggtacgtctt tatccaattc ttgggattga tctttattgg tattttcaat ttctttactt
    21721 aattctatct tatcagaatc aggtaaataa gcattgcgat taacaacctt tttcagattt
    21781 tgttttgcta atgggcttag ttcatcaata tgtttcatgc tatcttgaac aaaaaataca
    21841 ccttgacaat cattaggaat tttcaccgtc tgaatattag ttaagaagcc ttttgattgt
    21901 tccaacatgg aattaatttc ctcactgctg aatctagcaa ctccttcgac tttagaaaaa
    21961 tcagttgttt tgtaatagtc agcttttgca agtaacattt cgccttctat gactgaatct
    22021 attgaaacat ttttatcaaa ttttctttca acttctgatt gaacatattc tatcaatcct
    22081 tgttttattc ctattagttt ttctttctta attgataaaa tttcttttct ttcagggtta
    22141 ttttcttttg ttatactatc ttcaacttgt ttaatttttg aatcaagata acggctagtt
    22201 tgaaatggtt tttctttaaa aatcttttta ctttcttctt tttctactac tctttcattg
    22261 taaatgacct ctgctaactg atctttattc aataactgtt ttctaaatat ggtttcatta
    22321 accattgctc taacttcgtg atttgaaaat ttgtcaatat tcaaacttgg ataagatttt
    22381 ttgaagaatc tttctgcttg tttgtctaaa atttcatttg cctttgtaag catatctcgt
    22441 tcactactaa ttttacttaa catcaaacgt tgtttttgaa tttccatttt attattaaag
    22501 ataagtgaat tttcccatcg ttttaattca cctaatcgtt tatcaatgtt ttcatcatta
    22561 ataaataatt taaattcttt tgaaagattt ttcagttctc ctttttccaa aggtgagaaa
    22621 gttttttcaa attttaaagt gaagttttgg tcttgtttta acactttctc ttgactttca
    22681 agtttatcaa gttcggctag aatatcattg taactttgaa tttctaaatt ttttcttttt
    22741 aactcactta taactccttt ttcttctaat ttttttgagt aaaaaccttc atgaattgtt
    22801 ggtagttctt tttttccaag ttccgcatgc gatttttctg taatttgttg atcgatattt
    22861 ctatctttta aatattggtt gactttatca gcccaatctt tacgaatttc agaaacaaga
    22921 gattttctat cccaatcatt tgttttaata gaaaccattt taattttacc attttctaat
    22981 aaaatcgggt ttccattttc atctagttta ggtatctttt ttcgcttgtt aagaatattt
    23041 ccttcactat ctacttctct cattgttagc ataatgtgag catggggatt gttttcatca
    23101 tctctatgga tagctacatc tgcaatcatt ccttcgctga caaaattatc tttaacaaat
    23161 tcttctatca gtgatcgttg atctgtatta tttaattcaa ttggcaatgc tacatttact
    23221 tctcggcaaa gttgagaatt cacctgtttt tctgctaatt ccattttgtt ccataaagtc
    23281 tgtctatcta aaaattcatt aggtacataa tcaggcttta aaataaaagc ttctggttta
    23341 acagttctat ggttgtatag attagttttt tcatatagtt cactatacaa tttttcaccg
    23401 cttcgataag aagccattgc aattaaactt ctttttccgc cttctctttt tgctattgtc
    23461 atagataaat ggaagattgc caattgtatc acctctcttt cttttcaaac atgagcgtag
    23521 cgaattttaa caaacacgct tgacgataaa acgaaatgta aattaagttt tatagcacaa
    23581 ttaccactaa atgaaattta ggggtataag tgcgccctta gtaaatcatc taagggaatc
    23641 cttgataaat taattttacc acttatcatt ataaaagtaa atatgtttaa tctgacattt
    23701 tcatttatat ttattgattt tagaaaaata atataatatg atagagttac ataatatatt
    23761 aggaggcgta tttcatggaa aatcaagatc aaaatattaa tgcaattaat ggtaatttta
    23821 attctaaaac taagcccaaa aaaagaaaga agaaaactgt ttctgatatt gaacttcaaa
    23881 ttaaagaatt acaaaagaaa aaagaagaat taattctaaa atcaaaagca gatattggtg
    23941 attttgtcct ttctactctt tcaaaacttg atatttctat tgaatcgatt gaagaaaaca
    24001 aagaattatt ctatgacgaa ttagaaactt tattaaatgc gaatagtcaa aatttttctg
    24061 aattacttaa atagttatgg caaataatga tttaaatgac atcaacaaaa gaatagaaaa
    24121 actaaaaatt caaaaaaata ttttgcgagc gaatagcgag caaaatatta acagaaaaag
    24181 aagaacaaaa cgtctaattg aaaaaggtgc tttgttagaa aagtattttg aaattgacta
    24241 tttaactgta gaagaaacgg aagaattttt aaaaattttt tctgaatata ttaaagcgaa
    24301 taaacctaaa aagtatcaaa aaaaggaaaa ataattttcc tttttttgat acttttttaa
    24361 ataaaattga ttgttcttaa tgtttgtcct tcctttttta attgctttaa tatttcattt
    24421 actgattcta tatccaaatc gtaccaatca ccaaaagcga taatatcacc tgatactttt
    24481 ttttctataa aatcaactgt taaagttatt tctcttgttg acattggcga acgtgcttct
    24541 atttgatata aatcaaaatc gtatttttga tgattattta ttcctctcat ttctgttact
    24601 gtcgctttta taacttttaa aatattacct tcaaaattta ttttgggtct tcggaatata
    24661 tagtggaatt actttcttaa tagtttaaaa acaactggtg tttaaatcgg attttctggt
    24721 gggatgttag gacaatcaat agtattatat aaaagtatca atcacatacg agtgatacgt
    24781 tggggaaaaa taaaatagtc caatttactt gaccgcgtac tatggtacac ggtttataat
    24841 attcatgggg tgaaataaga tgatttatcg cattagtgag tttgcagata aatgtggagt
    24901 taataaagaa acgattagat attacgagag aaaaaattta ttacaagaac ctcaccgaac
    24961 ggaagctggt tatcggatat attcatatga tgacgttaag cgtgttgggt ttattaaacg
    25021 aatacaggaa cttagttttt ctttaagcga gatttataaa ttacttggtg ttgtagataa
    25081 agatgaagtt cgttgtcaag acatgttcga atttgtttct aaaaaacaaa aggaagtgca
    25141 aaaacaaata gaggatttaa aacgaattga aactatgtta gacgacttaa aacaacgatg
    25201 tccagatgaa aagcaattac attcgtgtcc aataatagaa acattaacat gagacattaa
    25261 cgaaaggggc ttttttatga ataaatttaa ggtaaacatt caaggaatga cttgtacggg
    25321 ttgtgaaaaa cacgtagaat cagcacttga aaagataggt gctaaaaata ttgagtctaa
    25381 ttttcgtcgt ggtgaagcag tatttgaact gcccgatgat attgaggttg aaagtgcaat
    25441 aaaggcgatt gatgaagcaa attaccaagc cggagaaatt gaagaagtat catcactaga
    25501 aaacgtggcg ttaattaatg aagatgatta tgaccttctt attattggtt ctggtgctgc
    25561 tgccttttct tcggcaatta aagctataga atacggtgca aaagttggaa tgattgagcg
    25621 tggaacggtt gggggaacct gtgtgaatat tggctgtgtt ccgtcaaaaa ctcttcttag
    25681 ggcaggggaa atcaatcatt tatcaaaaga caatccgttt aaaggtttac aaacatccgc
    25741 tggagaagtg gatttagcta gtttaatcac gcaaaaggat aaattggtga gcgaacttcg
    25801 gaatcaaaaa tatatggatt taattgatga atataatttt gatttaatta aaggtgaagc
    25861 aaaattcgtt gatgctagta cggttgaggt caatggggca aagttatctg caaaacgctt
    25921 tttaattgca acaggtgcat cgccttcgtt gccccaaatt tcaggacttg aaaaaatgga
    25981 ctatttaact agtacaacac ttcttgagtt aaagaaaata ccaaaacgat taactgtaat
    26041 tggctcagga tacattggaa tggagcttgg acaactattt catcatttag gttcagaaat
    26101 aacgcttatg caaagaagtg agcgactttt aaaggagtat gatcctgaga tttcagagtc
    26161 agttgaaaaa gcgttaattg aacagggtat aaaccttgtc aaaggggcaa cttttgagcg
    26221 tgttgaacaa agtggagaga taaaaaaggt ttacataaca gtaaatggca gtaaagaagt
    26281 cattgaatca gatcagttac ttgttgccac tggaagaaaa ccaaatacgg attctttaaa
    26341 tttaagtgca gcaggtgttg aaactggaaa aaataatgaa atcctgatca atgattttgg
    26401 tcaaacaagt aatgaaaaga tttatgcagc aggagatgtg acgttaggac cgcaatttgt
    26461 atatgtagca gcctatgaag gtggaattat tactgataat gctatcggtg gattaaacaa
    26521 aaaaatagat ttatcggtag ttcctgctgt tacgtttacg aatccgacgg ttgcaacggt
    26581 tggtttaaca gaagaacaag caaaagagaa agggtatgat gtgaagacat ctgtattacc
    26641 tttagatgct gttccaagag caattgtaaa ccgtgaaaca accggtgtat ttaaactagt
    26701 agcagatgca gaaacactaa aagtattagg ggttcatatt gtatctgaga atgcaggaga
    26761 tgtcatctat gcagcatcat tagctgttaa atttggctta acgatagaag atttaacaga
    26821 aaccctagca ccatatttaa caatggctga agggctaaaa ttagctgcac ttacgttcga
    26881 taaagatgtt tcgaaattat cttgttgtgc aggctaaggg aacttttttt acaactccct
    26941 attcaagtga accagctaat actgtactaa aggtgtgcag tagtttagca aagtctacaa
    27001 aagatttcat acactatttt gcgatcaccc attatataaa tgctttaagg gattttctaa
    27061 gtgcatttgt ggtcacaaaa ataatttaac aatgatgatt tcgacatcaa atctataatt
    27121 gataccttaa caccgcagag taataaagga tgaacaatat gtcagactta ttatccctac
    27181 cagacattaa aacaatagaa ccaccacaag aaaatgaaac cgatatgatg tttaaagttg
    27241 aagcagtcgg accacctgaa cgttgtcctg aatgtggttt tgacaagttg tacaaacaca
    27301 gttcaagaaa tcaactaatt atggatttgc ccattcgttt aaagcgagtg ggcttacaat
    27361 tgaaccgtag acgatacaag tgtcgtgaat gcggatctac cttctgggaa cgcctaatat
    27421 ctgtagatga aaagcgtagt atgaccaaaa ggcttttaaa gtccattcaa gagcaatcca
    27481 tgtctaagac ctttgtagaa gtcgcagaaa gcgttggtgt tgacgagaaa actattagga
    27541 acgtttttaa ggactatgtg gcactcaaag aacgtgaata ccagtttgaa actcctaagt
    27601 ggcttgggat agacgagata catattatcc gtagacctcg gcttgtattg actaatattg
    27661 aacgcaggac tatttatgac atcaagccaa accgtaacaa ggaaacagtc atccaacgtc
    27721 tttcagaaat cagtgacagg acttatattg agtacgtcac aatggatatg tggaagcctt
    27781 acaaagacgc agtgaacact atccttccac acgctaaagt tgtcgtagat aagtttcatg
    27841 tagttagaat ggctaatcaa gccttagata acgtcagaaa gtctttgaaa gcccatatga
    27901 gccaaaaaga aagacgtacc cttatgcgtg aaaggtttat ccttctaaag cgtaaacacg
    27961 atctaaatga acgtgaatca ttcctcttag atacttggtt aggtaatctt cctgctttaa
    28021 aagaagccta tgaactcaaa gaagagtttt actggatatg ggatactcct gatccagatg
    28081 aaggtcgtct ttgttatagt caatggagac accgttgtat gtccagtaac tctaaagacg
    28141 catataaaga cctcgtgaga gccgtagaca actggcatgt cgaaatattc aactactttg
    28201 ataaaaggct cactaacgct tatacggagt caattaacag tattattagg caggtagagc
    28261 gaatgggtag aggttactcg tttgatgcct tacgagccaa aatccttttc aatgagaagc
    28321 tccataaaaa gcgtaagcca cgatttaatt caagtgcttt caataaagct atgttatacg
    28381 atactttcaa ttggtatgaa gtgaatgatc acgacattac agacaacttt ggtgtcgatt
    28441 tttccacact tattaagaat ttggagaagg gtgatttata agcccttttc caccatgaaa
    28501 tccgaatacc cgaaatatat aaatatcaag cagaatctga acgaaagaat ataaaagaaa
    28561 gacaagccca gggaataaag attgctaaag acggtaaaaa atatagaggt agaaaacctt
    28621 tatttacaaa ggatagccct agattacagc atgcttttga attatataag aatggatatt
    28681 cagacaaaga ggttcaaaat ttaactggta ttaatcatga aacatttaga agatatagga
    28741 ttaaacataa tattcaacgc aatatataaa ataacctcac ctaattatac taatgtgatc
    28801 aggtgaggtt attttttaaa tctgtaaatt tgtaagagct ggcattaact cattttttag
    28861 ccatatctga ttaggtacat catctaggaa aaagcctttt gttgttaaaa ttaagttatc
    28921 gtattcatct gtcattttta attcagcaaa tggggattga ctagcaattt ctttagcaat
    28981 gctattcgtg tcgctattaa tttcttttac aaatttatta tgattatata catgtacctt
    29041 attcatttta tttattctcc tttatggggt accgtcagga aaatgcggat ttacaacgtt
    29101 aaggaaattt attaaagaga ccaattcctc agcactaaaa ttgataattg ggctttcttt
    29161 gttactatag tgttaggtaa gctttttact ttatcaccgg ttttcccctc acttcacacc
    29221 tacgggcgag tttccccaca tcccgttttc catctaatcc aattcattca atatctttat
    29281 gtgtatgaaa gatcagattg cttgatttag acatcttaca cgtaatttat tcttaaatgg
    29341 gtacggtaaa cgagcaataa tacgagcaaa agtataccta caaaaataat aactctgtct
    29401 aatttttttt gattcatatg cttattgctt aaaccatata atttcagtcc aagaaagcct
    29461 ccaacagtat ttgtaattac atctgttatg tctgtcgctc caatagcgaa gataaattga
    29521 attatttcaa aagtaagact taaaaccagt acaaaagcaa acttaggtaa aaatccgatt
    29581 tctttaaaat tgacattcaa aagcaagcca aatggaataa agattataac attatctatc
    29641 atctctctga aattcccagt agcagtaaat ggagtcaagt taagacttct ttgatgataa
    29701 ttaaatactg ataaaatatt gtattgtaat ttgaataaca ctaaccagat tagtgtcact
    29761 aaatataaag ctagcaatcc tctagataat atttttccca atataatttc ctctaattct
    29821 tttgtttaag ttgtatcatt agtatagcaa tgtcctagtt aacgtgggtt ttaaattaaa
    29881 aagctaacgt taccccaaaa gtgctagtac aataatgctg ttcattaatt tcgttggttt
    29941 cattccgcca tccttacctc cttgaattag tatgtgttga tccgggaaac actgtcacaa
    30001 ttacaccgtc tatattgttt cctgatatct cataacgaag attagtcggc acatgaatgg
    30061 tggtattttt agtaacagga taataaaaga tctcatattt ttccccattt acactaacag
    30121 aaatggtttt ttcttctttt aggtaatcca tatattcctc gagaacgaaa ttcttttctt
    30181 tcataatcgc actatgtggt aaaccaacat agcgaatatg ccatggttca tattgaattc
    30241 ctgttaactc tgttttgtcc tctggataac gtaaaatgaa cccgtatttc caagcatttt
    30301 cttctatcca ctttccttca ggggctcgtt ccattttcgt caagcttgat cctacatcta
    30361 gtgataaacc tgaattatgc tcactataac ctgctggtaa ggcatactca gcccccattt
    30421 cttggtaaag cacactttgc tcatcaaagt ctcgatagcc actattaata ataaaatgac
    30481 taacgccacc ctttacagca tcattgacca tctctgaaaa tttttgtgct atttcttttg
    30541 acatataaat attactatca agcaacccgt atccatttat taattcgtca tgtttagata
    30601 aattcacgat atctgacttc acactttctt ggcgaacagg atatttacta ttgattaata
    30661 gcagatttcc ttgataaacc tgttcttctg taattgtttt ctcttgggta ttttcagaag
    30721 tcccactatt ttctaaatgt tctttgggat tttgatcata attttgaaat tcgacttttt
    30781 cctgagaaaa cagtgcttca ttaacgtagt cataacctaa gtatattaag aataacaata
    30841 acaataaaaa aaaacaactt cttcattttc agtctcctcc ttaactatat agttggaagt
    30901 atgaaatatt tctagaatct tccccttaaa cggcacaatc tcgtttgaga ttgtgccgtt
    30961 ttgccccgta aattacagtc aattatttcg ccctactgga tttactatta tcaccaatgt
    31021 agatgaattt tcataagtga tacccatgct gaatttaacg aggctgaact gcctgttgac
    31081 aatgggcggt gtgaaatacc acccctctat gcgatcagtc ttattatcag gctatcttgc
    31141 cgcagcgcac gcagataatg accgcaatat cgctctgcct tacatcttca atactatcta
    31201 ctatatataa attccctaag aaccagttac atacgtcggg tttcctgccg aaagagttag
    31261 cttatatagt ttgtccgtgc aacggttaaa agtttattta acggggaaat caaaatagct
    31321 attggggtat ggttcgtctc ttaatacata gtgccaccat tcgaggctat atgcttcaaa
    31381 cccactgttt tccatgatgg agcgcaaacg tctgcgattt tgcgcttcat tgcatgatat
    31441 tccatttgcc gcatgatgag agcgttcatc cataaaatca aatcggctcc ccattggtac
    31501 aagctcaccc gtgtctaatc gataaagcgt aagatcaatg gcactgccgc ggctatggct
    31561 tgattttgaa gccacgtatc cttttgaaat catctcagtt cggtcaatat tgggataata
    31621 actttccttt gtcaggttat tttccggctg tgcagcccat tgcataaaac agtttacagc
    31681 acgcttagga cggtaaccgt cccatagaag caatccgtac ccttgggtag cagccagttc
    31741 ttttgccttc aaaagcgatt cagccaactc gtatgtccct acaatgcgat ttacttcata
    31801 accgtcaacc ggttttccgg tgaaattatc ccaagtggca tatttagcgt cccaacgaac
    31861 accgtgtact atttcatcta aaaaagtaaa tcctatttcc atgcttatca cccctttaac
    31921 gctaatacga tcaagcggtc aatcagttcg ggaagtgcaa tacctgcagc ggccatcata
    31981 cggggataac gactgtatga cgtgaaaccg ggcagagtat tgacttcgtt cagtacaatg
    32041 cggccgttat cttgtaaaaa catatccaca cgggctagac ctctacagcc gagcgcttta
    32101 tatatttttt ttgccgtttc ctgtatccgt cctcgctcct ctgctgaaag gtctgcggga
    32161 acggttataa ctgcgttttc agagcctttt tccggctcga cttcctgatg aatacgaaag
    32221 attccgtact gcagcctgat ttggtccacc tcgccaacaa ctaacgcggc actgtttccc
    32281 aataccgcac aaccgacctc acagcccgaa acagcctgct caattaagat tttgctgtca
    32341 tattgtcttg ccgattcaat tgcgtagtcc aattcgtccg cgctattgac ttttttcaca
    32401 ccgaaggatg agcctgaacg cgccggctta acaaaaacag gataggtaaa cgtagctgcc
    32461 accggcctat catctttatt aataacccaa aaggcgggag tagctatccc agcatttttc
    32521 gcaacgatgt atgtcaacga tttgtccata caaattgctg agctttgaat atcgcagcct
    32581 acaaaaggga taccggacaa ttcaaacaga ccttgtatgg atccatcttc acctgacttg
    32641 ccatgcaaag ctgaaaatgc tacatcaaca tggttgattt catattcatg gttcttttta
    32701 acaagtaatc cgtgcatttt tttatccggc gagagtacag ctgaatagca attgtcgttt
    32761 tcccattccg cgcaaggttt ttcgcacatt ttccatacac cagatttcgt aattccaatg
    32821 tataacggct cgtatttttc tttattaatg ttagcggcta tctctattgc agattttacc
    32881 gatacgtcat gctcctctga gcaaccccca aacagtattg caacttttat tctattcatg
    32941 ctcctgtctc ctttcaaaat ccaaacagtt tttaatggtt ttttcaacgg tatcacgcaa
    33001 cgcttgctcg gtataatagg ccgtatgcgg tgtgattatc acgttaggca ttctttgaag
    33061 tttaagtaaa aattgattat caattggttt ttgggtgcaa tcagagtaga aaaactcttc
    33121 ctctccttcc aatacatcca atgcggcacc gcccagtttc ccgttttcta atgctttaac
    33181 caactcatag gtatctacaa gtggaccgcg cccagtattg ataagaaatg ctccttgctt
    33241 cattctctgt atttgttcgt ggctgataat atagtgcgta tccgtattga gcggcacatg
    33301 aagcgtaacg atatcgctat tttgcagcaa ctcatcaaac ggtacatagt ttacctctat
    33361 acttcggctg cgactataag ccaacacttt acatccaaat cctcgcagcc gctcaataac
    33421 cgctttgcct atctggcccg ttcccaccac accaactgtc atgtcgctga gtaccttgcc
    33481 acggtcgctg tccaacctga aatcatgttt ttccacagag cgcacaatcg attttacgtt
    33541 gcgtactgcc ataagaatta gcatcatagt ataatcggca acgctatccg gcgagtacgc
    33601 cacattgtcg acagtgatgc ccattctctt agcagcagtt gtatctatat gattgcagcc
    33661 gatgcttcgg gtagaaatat atttcacacc ggctctcttc agcgcaagaa gaatagaggc
    33721 ggaaatctct gatttatgtc ccacactgat acattgattg aaaggcgcgg atttggcgtt
    33781 ggattccgac acgttggcgt taattatcgt tgccataacg ccaaagcgag gcgaaagagc
    33841 atggaatgca tctgcctcat cctgctcaca tccataaaca gtaatgccga tgttattcat
    33901 aattaagacc aaccctttct gtgaaaggca ccaaataaaa cggggatgcc aatggtaatc
    33961 ttgtcaaatc tttctctgaa gaacgaaaac ggctcgttct tacggtatta agtctaccgt
    34021 gtaagaacga gccgtttctt aatattaaat tgttaatttc ctaagaaaaa gtaaagataa
    34081 ccttgagatt ttcctaaaaa attatataca tctcttagga cctcctttta tcaaccaagt
    34141 ctggcatcgc tggaagctct accctaaacg tcgtatagtt atcattgctt tccgcgtaaa
    34201 tctgccctcc atgctgaaca ataatttctt ttgcaatcgc caatccaagt cccgcgccac
    34261 ccgtatcgga agaacgagca ttgtccagcc tatagaactt ttcaaatatg gcagctagct
    34321 tatcttttgg gatgcttcca gtgttcttga attcgattga caccacatcc ccggagaggc
    34381 ccgcggtaat gtcaatgatg ctgttatcct cactgtatgc agcggcgttt ttcaaaatgt
    34441 tgttaaagac tctcgcgagt ttatcagggt cgccggacac ggtcagatcc tcgggggcgt
    34501 gaataaccgc ctgttttcca tgtgcggaaa gctgaggata aaattcatcg gtcatctgca
    34561 ccagcatata gtataggtct atgtgcgttt ttgttagcgt tatcgtttgt aggttatacc
    34621 gtgtaatctc aaaaaactcg tcgattagct gttcgagtcg atacgctttg tccaacgtga
    34681 tatgcacata ctttgccttt tgatctaccg gcatgtctgg agcctcgtca agcaggctca
    34741 aataaccgat aatggatgta aggggcgttt taatatcgtg cgccaagtac ataacaacgt
    34801 cattttttct ttgttcggcc agctttgcat cctgctctcg cttttccaga gtccgtttta
    34861 atgtgttgag cttttgttcc ataacatcca tttccgcaga aagctcaatt tgtttatctt
    34921 cgttctgaat aagtacatca atgccggtat ttatctcgtc aaagtatttt gcgaattttg
    34981 aaagcatgac gcgacataga ataagaatac taatgacaat cgccacataa ataaagatat
    35041 ctatattgtt ccgtatggaa tattgatata atttcatcgc gtccaggtga tttaagtcat
    35101 atttgttttc caaaatactt aagatccaat ccccaagttt ccctcggatc attgaacgaa
    35161 tatacaacac gaatacaatt gctaccacaa caattgcaac gatatacatg taaagttttc
    35221 gttctagttt ggaatagtcg ttttttttat ttttcaattt tataaccaac cccccatacc
    35281 gtttttatat atttcggatt atcaatggtg tcgttcattt tttcgcgcaa atgccggata
    35341 tgcacggtga tggtgttgtt gctcttgctg aaatattcgt cgccccatat ctcatgaaat
    35401 agcagctcgg agctaaccac attccccttg ttttcacaga ggattcgcag tattgaaaac
    35461 tcggtgggag taagggataa ctgcttctcg ttcagataac actcatgggt gttaacatta
    35521 atgacaaggc cggagtggac gataacattt tcgttctgct cctttactcc actgaatttt
    35581 ttgtatcggc gcaactgggc ctttacccga gcaattaact ccagtgggcg aaagggcttc
    35641 gttatataat catccgcgcc gattgttaac cctgtaattt tatctacctc tgtatctttc
    35701 ccggtcagca tgataatcgg ataggtgtgc ttgtccctta ttttttgaca gatagtaagg
    35761 ccgcttgtgc cgggaagcat gatgtccaat atggcaaggt caatctcaga cttgtctata
    35821 cattccaatg cttctttggc ggtatagtat ttgaaaaccg tataattctc gttttttaag
    35881 tataattcaa ccaaatcggc aatttcatgt tcatcatcca caataagtat tttatcgctc
    35941 atagttatca ccctttcaca taagtttgcc cttaataatt tatcagatta tagggccgaa
    36001 tttatacctg aataattcat actttttata aactaccaaa ttttataatt atctgtttag
    36061 ttttatgctc aatggttctt tttctcaaaa atatttttct aaagggttta atttattttt
    36121 gctaactgat taagttcaag aaagacctca ttttgggcgc actcatccta tcggatggtt
    36181 aacgaatttt tttgaatggc gcaataaacg caattaacac tgcagtacct gaatgttttg
    36241 tagaatccga taaaatagct tctggtaaac atggtaacta cttaatttca agtattgtct
    36301 tcttccggaa tgaactatct ttccagcaat tttaaagaga aataagcgaa tagtagaaac
    36361 ctgataccct ttcgtttcat tggtaaaaca cagtgtccgc atgaagttca cgatattgta
    36421 agccaatagg cttacgatca tacgagcatg attttctata aaacgtgggc tatctgtttt
    36481 atccaagtaa aagccgtttt ttgcttcctt aatgtaattt tccatcgttc ctctttttga
    36541 atacgtttgg aaaaccattt ctggagagac gtcttttgaa aaattagtaa tgatgaattc
    36601 atgtctaaaa agcaattcac tagcttctct ggttgatttt atgcagatcc ttctggattt
    36661 tccccatgac tttgcttgat aagtggcgtt atagtaatga acttctttct tactccaatc
    36721 gtgatgatcc ttaatggtaa tgaattgatc agcgattctg tacagattac gattggattt
    36781 caaacggata gtatacaaac tatcgtactc ttcacaaagc tcatacaaat caggcattgc
    36841 gaatccacta tctgcacgta ccataatagt gcttactggt gtcacagagt gataatgctc
    36901 aaataatgga cgagtaaatg ctgcgacgcc ttttgaggtg tagacatttc cagaacgaag
    36961 ttctgcttta agaaagtctc cggtaagacc atcaaaggca acgagtggat gataaccggt
    37021 tgtctggtaa tgcgcattat aatcggtcat ttcttggttt ccaaaggtat cactgtgagt
    37081 agaatctaaa tcgaaaatca tttcgttcgt atttcgaatc gtccgtgctt tatcaatcaa
    37141 aatctggtta accttttgta gctggacgat attttctgtt gatatccgat cccaaaagcg
    37201 agaaatggat gactgtgaag ccaaccgctt tttgcttaaa acagcttgaa agataggatc
    37261 cgttgctaat atattggctg aagaatctgt aggatagcct gcaatcaact gcaagatgat
    37321 ttgttccaga atagattcat tttcatgaac atgatacagt cggtcatctt gaatctggat
    37381 gtttttacat aagatttggc taaactcaaa tttgttcatg aattcttttg ctaatattaa
    37441 gccggaatct gaggacaaat ttccaccaga gtgagatact gtaacatttg aattgaaaag
    37501 tagacgattt tcgtgtaaag ttgccattga gagaacccct ttctttggtt aggtttagtc
    37561 actttaacca tagcagattg gggttctttt tgtacaccca aagggtgcga ataaacgaaa
    37621 caaaatagac tgttataaca aggtttttga aacgtttttg
//
LOCUS       DAXLPQ010000023        36706 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.023, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000023 DAXLPQ010000000
VERSION     DAXLPQ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.023"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..300
                     /locus_tag="ACF3UO_001416"
     CDS             <1..300
                     /locus_tag="ACF3UO_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3657453.1"
                     /translation="DGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKEN
                     RKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(653..1501)
                     /locus_tag="ACF3UO_001417"
                     /pseudo
     CDS             complement(653..1501)
                     /locus_tag="ACF3UO_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1654..2766
                     /locus_tag="ACF3UO_001418"
     CDS             1654..2766
                     /locus_tag="ACF3UO_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3657454.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2844..3137)
                     /locus_tag="ACF3UO_001419"
     CDS             complement(2844..3137)
                     /locus_tag="ACF3UO_001419"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFD3657455.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3305..3619
                     /locus_tag="ACF3UO_001420"
     CDS             3305..3619
                     /locus_tag="ACF3UO_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFD3657456.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3640..5619
                     /locus_tag="ACF3UO_001421"
     CDS             3640..5619
                     /locus_tag="ACF3UO_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3657457.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5632..5958
                     /locus_tag="ACF3UO_001422"
     CDS             5632..5958
                     /locus_tag="ACF3UO_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFD3657458.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5974..6492
                     /locus_tag="ACF3UO_001423"
     CDS             5974..6492
                     /locus_tag="ACF3UO_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657459.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6492..7844
                     /gene="celB"
                     /locus_tag="ACF3UO_001424"
     CDS             6492..7844
                     /gene="celB"
                     /locus_tag="ACF3UO_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFD3657460.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7928..9433)
                     /locus_tag="ACF3UO_001425"
     CDS             complement(7928..9433)
                     /locus_tag="ACF3UO_001425"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFD3657461.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9525..10115)
                     /locus_tag="ACF3UO_001426"
     CDS             complement(9525..10115)
                     /locus_tag="ACF3UO_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3657462.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10294..11940
                     /locus_tag="ACF3UO_001427"
     CDS             10294..11940
                     /locus_tag="ACF3UO_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3657463.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11989..12708
                     /locus_tag="ACF3UO_001428"
     CDS             11989..12708
                     /locus_tag="ACF3UO_001428"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD3657464.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13187..14134
                     /locus_tag="ACF3UO_001429"
     CDS             13187..14134
                     /locus_tag="ACF3UO_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657465.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14146..15066
                     /locus_tag="ACF3UO_001430"
     CDS             14146..15066
                     /locus_tag="ACF3UO_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657466.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15107..16564
                     /locus_tag="ACF3UO_001431"
     CDS             15107..16564
                     /locus_tag="ACF3UO_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3657467.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16909..17523
                     /locus_tag="ACF3UO_001432"
     CDS             16909..17523
                     /locus_tag="ACF3UO_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3657468.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17516..19240
                     /locus_tag="ACF3UO_001433"
     CDS             17516..19240
                     /locus_tag="ACF3UO_001433"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3657469.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19237..20688
                     /locus_tag="ACF3UO_001434"
     CDS             19237..20688
                     /locus_tag="ACF3UO_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3657470.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21161..23314)
                     /locus_tag="ACF3UO_001435"
     CDS             complement(21161..23314)
                     /locus_tag="ACF3UO_001435"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFD3657471.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23316..24362)
                     /locus_tag="ACF3UO_001436"
     CDS             complement(23316..24362)
                     /locus_tag="ACF3UO_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3657472.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24512..25801
                     /locus_tag="ACF3UO_001437"
     CDS             24512..25801
                     /locus_tag="ACF3UO_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFD3657473.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25814..28516
                     /locus_tag="ACF3UO_001438"
     CDS             25814..28516
                     /locus_tag="ACF3UO_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFD3657474.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28501..29358
                     /locus_tag="ACF3UO_001439"
     CDS             28501..29358
                     /locus_tag="ACF3UO_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3657475.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29429..30286)
                     /locus_tag="ACF3UO_001440"
     CDS             complement(29429..30286)
                     /locus_tag="ACF3UO_001440"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3657476.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30497..32668
                     /locus_tag="ACF3UO_001441"
     CDS             30497..32668
                     /locus_tag="ACF3UO_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFD3657477.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32736..33077
                     /locus_tag="ACF3UO_001442"
     CDS             32736..33077
                     /locus_tag="ACF3UO_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3657478.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33353..35107)
                     /locus_tag="ACF3UO_001443"
     CDS             complement(33353..35107)
                     /locus_tag="ACF3UO_001443"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657479.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35118..35954)
                     /locus_tag="ACF3UO_001444"
     CDS             complement(35118..35954)
                     /locus_tag="ACF3UO_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFD3657480.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35956..36639)
                     /locus_tag="ACF3UO_001445"
     CDS             complement(35956..36639)
                     /locus_tag="ACF3UO_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFD3657481.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11843 a         6446 c         7481 g        10936 t
ORIGIN      
        1 gatggcttag caccaggagc atatcagctg gtagaaactc aagcgccaac ggggtatgaa
       61 ttggatgcga caccagtaac tttcaagatc gaaaaagaac aagaagtggc gatcttttta
      121 acaaaagaga atagaaaagt tgctgatagc tcagatataa gaggaaacaa tccaacaagc
      181 agtggaaata agcatcttcc aaaaactgga gaaaccatca ttagccagtt tatattgtca
      241 atattgggtg tgctacttgt tttcatcagt ataaaattta gaaagaaacg aaatatatga
      301 gctaaaataa aaaattgaat aagcatagtt tttaaaatca actagtaccc atcaattgaa
      361 tggaaactac cgattttaga aggggtatac aaacaaatat tagtatcgga gtagagaagg
      421 ttgaacccaa ccagtaaata agtaaagaca attttgtgct gcgttgagaa gtgaaaaata
      481 aacctttgta gtaatactag ttaataaaaa atatacaaaa acactgcgaa aatcattctt
      541 gagtttcgca gtgttttttg cctaatgact caagtttatt gggtaatact ttgattttct
      601 ttctacaaat aatcagcgat cagttgtaat tttttctcta gttttaatgg ctctttgtca
      661 ataaggagaa aaacaagtcg ggtcttttgt ctcggaaagc ttcaaccaac tcgtgaataa
      721 aggttacgcc tccttgaaag gcgtggaaaa accaagtaat cgatcaatca ccaatttcgc
      781 atttggtaga acatgtttgg tgagctgaaa gtaggtggcg ttcatgtctg taactaagaa
      841 ttctatttct ttaggattag tgcagctaag gaaatagttt gttaatcgag gaattttttg
      901 tgtaggtaaa ttttctcgat taatttttct gtctcgccat ccgcggaaat aaaactcagt
      961 ttatcctcaa cggaaacgtg agaacgaaat tcacaaccct caacactcaa gacagaattc
     1021 ttttggaaga ctttggtaaa tagcttctca actctttcaa tgtgcgaata acggttgtca
     1081 aagataccta acaacttttc gaaataaaaa ataacgacac tttttcagtc agtaaagaag
     1141 tgattttatg tctgacatga tttgaaatcg agtgccttgg acggataaaa taactttgag
     1201 cgttccaatg gcttcgacag tttttacagg tatagcgctg cttttttagg cgtataacca
     1261 ttggcatatg attatattat tcaaagtgga caatggtttc cttcttcttg tttttcacca
     1321 ccattaattt cctatttcca tctaccacag cagaaccaca atttctacag acacatggag
     1381 cagggaagag aactgcagca acgatcaatg tttttttctt ctgtaaggtt tcgtaagaga
     1441 cctctgtaat catcaaattt ttgtctattg atctcagaat ttttttgata gaaccattca
     1501 taaagcatat cgttctctca gttgtttatt ttgtggtgat ttaatcatac aagaaaacga
     1561 tatgtttttt tataaaaaca tgaataggaa aaatagttga caagaaaatg acaacgccat
     1621 atgatgttcc atagtattta caacctgtca tagatgactg taaaaaataa aagtaaaaag
     1681 aaaggacgac aacaggtgga tttttatcag tctctacaac tagatccgtt tattttaaaa
     1741 caaaaaatac gagaagcagc ttctaaaaaa gaaaagtgca tgtatatttg ttcattgttt
     1801 ttacgatcat tattcatcgt attgtttgcc atttgtttta tcattataat tacaacatta
     1861 tttgaatcga agcataaacc atacgctgtg gttttattct gtatgttgat gagtattcgt
     1921 tttgttgact ttggttataa gatttcccat tcgatcatag gtttagcaat cgtcatgttc
     1981 tcactattag tagcaccgta tgtccagctg atcaaatggt cagttatggg catgttgatt
     2041 cattttattt tactaagcag catattaatg gcaaccgcta gtgatcccaa aatggggaat
     2101 gcttctttgt acggcttttc atatctcttt attgtttatt cgttacctaa agattcgttg
     2161 aacaagaatt tctttacaca aacaagtagc ttattatttt tgtttttttg ttggttttca
     2221 gttcttcttt acagaaaaca tcgagaaaag aacaaagaca aaagcttgtt taaagagatt
     2281 tttttgaaag gcatgtattc gcaggaaaaa atttggatgc tcatctatgc atttggcatt
     2341 agtcttttga tcgttgcagg agagtatgtc ccttttcagc gattgatgtg ggcagggttt
     2401 gcattttctt ctattgtatc tagctatgga ttgatgtcga ttggtttcaa agaacgagca
     2461 gtagaccgaa tcattggctc attgattgga tgtgttttat ttattggtat cagccaattt
     2521 attcctttta actgggtcgg tatattaggt ggtctagctt taggtgtttg ttctacctat
     2581 agatataaaa cagtttttaa ttcttttggt gctttggcaa tcactgccag tttattcggg
     2641 gttccaggag cagtaacgat ccgcattttt gagaatatcc ttggggtatg tttaggaatc
     2701 atgtatattg gggtgactga aatacttatc cgaaaaataa gagaaaaaca cggtttgaat
     2761 cattagatga gatcgaataa aaaataagga aaaagtgaag atacacatgg atgataaatt
     2821 gctatcattc catgtgtatc tttttacggt aaatcagtga aacgttcgac tttcattttt
     2881 aatttatact ttttacggag ttcgtttatt tgagccatca tttcggattt gtgatgcttt
     2941 tcgattgctt cttcatcttt ccaacggtcg atcagtaaaa gagattctgg atcttctagt
     3001 ggaaagtaat agtcatattt ctcgtttcct tcttctgcac gaatcgcttt gacaatgttt
     3061 ctttcgacca tttcttctgc aaattttctg gcttgtccat ttgtacttgt atacaaaata
     3121 ttcactgtga tactcactaa atcccctcct gaaaaaattc tatcactagt atatcacggt
     3181 gccagaaatt attattcaag atatgataca cattttttcc gcaatgctac ggaaatatat
     3241 attttgaata gaaaacgctt acaagatatg cttggtttat aaaaataaaa ggagtgattg
     3301 atttatgaaa aaagcattga ttatttgtgc ggcaggaatg tcatcctcga tgatggcctc
     3361 aaagacaacg gatttcttta agcaaaaaag agaagaggta ctcgtagatg cagtttcagc
     3421 tacagaaggc gataatatga ttaagaatag tgattttgat ttatttctga tcagcccgca
     3481 aacgacgatg tttttggata aattcaaaaa attaggagaa tctgttggaa agcctgttgt
     3541 tagtatccct ttccaagcgt atgtcccaat ccctacaggc atccagaagt tagcagaggt
     3601 gatcgaagag aacatatgat ggaataggag tggatgataa tgaaacagaa ggaaaaattg
     3661 ctgttgagat atttgattga tcacaagaag gagtatgtca ccagtcaacg tttagcttct
     3721 gaattgttat tatctgatcg gacaatccgt aattacttgc agcggatcaa agagttagta
     3781 gaaaaaaacg gaggtaagat cattgctaaa ccaggttatg gctaccaact gcatatttta
     3841 caaagactga catttgactt gtttttgagt cggcaagaaa tagtacctgg atatgctaga
     3901 gaaccgcaag gattttatga gtccgaagat cgacaaaagt atatattgaa ccaattgctt
     3961 ttggaagatg ccattctttt tatggatgat ttggcagaag agctttatat cagtcgttcc
     4021 agtttgacaa aggacatgca agaaatcaag gagcgattga ttccatattc actaaaaatc
     4081 gtttctaagc atggtcaagg gacatggatc gaaggggaag aaagaaatcg acggcatttt
     4141 atcatggata ctttttttgg aaaccattat ggaaattcat tgaaagaata tttagggcaa
     4201 agccgttttt tcccagacat cagttttgaa gagctagtca ttatcattct cgatgaaaca
     4261 agagaagcta agttaaaagt ttcggatttt atcatacaga atctgacttt acacttggct
     4321 ttggggatca aacggctccg agaagggttt gaaatcaagg aattaggcat cgaacaagaa
     4381 gtttctaagc gagtagagta tcaagtggcg cagcggatcg ttcaacgtat tgaggtaatc
     4441 gcaggtgtat cgtttcccga agaagaaatt gcttatttga cattacatct catggctaag
     4501 tcgaatcaca aagaaaatca aaatgatcag gaactatcaa aggaattagc gaaagttctg
     4561 aaaagattgt ctcaggaatt tcatttttca ttagtagagg atctccagct tttcaatgga
     4621 ctactcgatc atttgtcacc gatgatgatt cgattgagcc gaggtattcg cattgagaac
     4681 ccattgactg aggagataaa gaaagaaaat cccaaagtct ttgacgcagt aaaaaggcat
     4741 ttcagcaaca tgccggcttt gaaaaactat accatcaatg aagatgaatg ggcctatttg
     4801 gctttgcatc tcatggcggc attggaaaaa gaaagagctg cgcataaact acatgcattg
     4861 attatctgtg caacgggtta cggcagtgcc caactattaa agaatcgcgt agtcagtgaa
     4921 ttcggtaaaa atattacagt ggtaagtgta aaaggctatt atgagatcaa tgaaacaact
     4981 ttaaaaggaa tcgacctgat tatttcttct attgatcttt cgacaatgtt tttcaaaatt
     5041 ccagttttac atgtcagtat ttttttgaat gaagatgatg ttcgtaaaat acgaaaggta
     5101 gttggagaat ctatacccta tcattcctca gatagaccga taccagcatt ttctctacag
     5161 caaaaaaagc agatttacac cgaacagttg tctgaaaaat ttttcaagac ttatacgtac
     5221 gaaccgaaaa aggaagaaat tcttcatgat ttgctgcaaa agctgagcat aaatgaagaa
     5281 gaaggatata taagagaaat gcgaaagcag atccagcaac gtgaaaatat gggacaaatc
     5341 atattcagtg atacagtggc agtcccacat cccgctgttc cagttggaat cgaaacaaag
     5401 gtagccgttg cattgattcc ttctgggatg cagtgggatc aatatcaaga aattcatttt
     5461 gtttttttag tttcgccttc ttatgtcgaa aatgaaggaa ttacggtcgt gactaaagca
     5521 atcgttaggt tagttgacca gctaaaagta cagcaggaaa tcttagctga acctattttt
     5581 gagaatttca gcagtaaatt tatcaaactg atcgaataag gaggaaaaca gatggctgaa
     5641 aaaataaaca gtgaaacact acaagtgact tcttttgata tcattttcca tagcggaaat
     5701 gcacggacac tgatacatga agcatttcgc tcgatgcgta aagagatgtt tgaagaagta
     5761 gaagagaagt tgcgacaagc aaatgaagag attcttcatg cgcatcagtc acaaactcaa
     5821 cttctgaaag aatatgccag cgggacaaaa atagaaatgg aaattatcat ggtccatgca
     5881 caagatcatc tgatgacgac gatgacatta ttggaagttg cacaggaaat gaattatttg
     5941 tatcaaaaaa ataaatagaa aggaaggatc attgtgcagg atacagtaaa aaggaaaatc
     6001 gaattagaaa aaaagcaact tagtttgaaa aacatgtatt tcaatcgtta tctaatcgta
     6061 cgttacctga ctgccttttt ctttttcatg aacatgcaat ggatgattct gcttctatca
     6121 gctaaaagtt taggaagtag tttaccgatg attctgattt tagctatttt gcctgcagta
     6181 ggagaacaag taaagcttta tcgaaaacac caaacgaacg ttccatggac aaagtggtat
     6241 tttttgttcc agagtgtctt taatttatta gtgattccag tgttgtttac ctcaggattt
     6301 acattcttgt atccttttat ggcaaataac aatggaggac agttatttgt tttcattctt
     6361 gttgtaagcg gtatttttgc cagtgcattt atacagtatc gtttaaagaa aatttcactc
     6421 aaccaagacc aacagtatat ccgtattaaa caatatgaaa aagcgttata tttaggaaag
     6481 gagaataact aatgtttgat tttttgcaga aatacctgat gggacctatg gggaaaattg
     6541 cgcaacttaa aatcgttcgg gctgtcatgg cagcggggat ggcttctatt cctttcacga
     6601 ttgtaggctc gatgtttttg gttttaaata ttttgccatt accgttccca tttttagaag
     6661 gattttttaa tgcaactttt ttcaaagtta gtgacttgta catgatcgtc aatacaatga
     6721 cgatggggat tttatctatt tactttgcca ttgtgtttgc ttatgaatta acgtcaattg
     6781 aacgagatga acaaaaatta aatgttaatc cgctcacggg ggcattacta tctgtttttg
     6841 cattctttat gtgtatccct gaattgatca tgactgatgg taaaatcagc ttgattgctt
     6901 ctatcaatga gacagaaact gtagtaaatg gtattaggat gggctctttt gtcgaacgtt
     6961 taggaacttc aggaatcttt acagctatta ttatgtcgat tattgcggtc gaattgtatt
     7021 gtatgtgtgt caagagaaat tgggtcataa aaatgccaga tgttgttccg ccaggagttt
     7081 ctcgttcttt cactgctctg atcccaacat ttgtcattgc gtttgtggtg atgatcatca
     7141 atggattatt agttgcacta ggaacggata tcttcaaaat gattgctatc ccatttgggt
     7201 ttgttacgca gttgacgaat acatggcttg gtgtcatggt gatttatttc ttgatccatg
     7261 cattgtggat cgtagggatc catggagcga atatcatcac ttctttcttg accccgatcg
     7321 tattagctaa tatggcagct aacgcacaag gcgcaaatta tccgttggca ggagaattca
     7381 acaattctta tgtaaccgtt ggtggatcag gtgcgacttt aggattgatc atctttattg
     7441 cattcctcgc gaaatctgat cagctgaaag tgttaggaaa agcctcactt gtaccaggat
     7501 tattcaatat caatgaacca atcattttcg ggatgccaat cgtctacaat ccctatttag
     7561 cggttccgtt tttcttagct ccgatggctt ctgctacact cgcttatttt gccattcggc
     7621 tggaaatcgt caaaccgatg cttgcacaga tgccgtggcc ttcaccagtc gggatcggag
     7681 catttgttgg tagtggtggt gattggaaag ctgctgtgtt agcagtcatt tgtgcaatca
     7741 tcgcattcat tatctggttc ccatttatca aattctatga taataaatta ttaaatgaag
     7801 aaagagaaaa ggcagcagaa ttagctagtg aaaagttaaa atgatttcta agaaaaaagg
     7861 aactgtgaca aaaaatcaca gtcccttttt ttcttagaaa tgggaaacca ctagtatata
     7921 aataccatta ttcttcaatc aaccgcttca cgattgcata atccccttca taaggttcat
     7981 ctacaccatt gattttttga tagggatcca cgccttttcc cgcaataacg actgaatctt
     8041 gcggagcgct ttctgctaaa gcgcgtcgaa tcgcttcagg acgatccatt tcataatgaa
     8101 cgatcaaatc tggattagta attgcttcat tgatttcttc cgcgattttt ttcggatctt
     8161 caaatgctgg gtcatctgcc gtcaaaaagg cgatgtcagc tgtttctgat agcacttttc
     8221 caaaatcatg tcgacgggag attgctttgt ttcctgggct gcctaataca acaattacac
     8281 ggccatctgg atgttcattt ttggcaaatt ccagcaatgt tttcaagctt agataattat
     8341 gtgcatagtc cacatagaca tgcgctccat tggattggat caattgatcc attcggcctg
     8401 gtacacgagc ttcttttaat ccgtcttgtg catcttgact ggaggcacct gttagtgctg
     8461 cggcaatgat cgcactggct gcattttctt ggttgaatcc tccagccagc aaaatatcat
     8521 aagcagtatc gcagatagct aagcgatctt catgagaaga taaagtaaaa ccgtgagtac
     8581 ctttatctga acggatcact tgataattgc tttcttccga acgaccataa gtgatcgttg
     8641 gaatctggaa tagatcggct gtttccctaa gtaaatcaaa atagtcactt tcatgattta
     8701 aaacaactgt ttttgaattc aagatcaatt gtcgcttgca atagaaatag tcatcaaatg
     8761 tcggatgttc gatcggactg atatggtcag gcgagatatt caagaagatt ccgacatcta
     8821 aagtcaagcc gtatacgcgt tgtgttttgt aagcttgtga agaaacttcc atcactagat
     8881 gagtcatacc attttcaact gcttctgaca tcatacgata taaatctaat gactcaggcg
     8941 ttgtcaaatg ggatttgaaa tatgttttgc catctaacgt tgtattcata gtagaaagca
     9001 atgctgtttt tttatttgtt gtgtgatcca agattgcttt tgtaaagtac gcagcagttg
     9061 ttttaccttt tgttccagtg aatccgatca ctttcaattt attttgcgga tagtcgtaaa
     9121 aagccatagc aagaagcgcc attgctttac ggatatccgt tacgatgatt cctactgctg
     9181 aattttcgta tggttgttct gatacataat attgaatacc ctgttcgatt gctgaatcca
     9241 aatattcttc tttgaaattc attcctttac agaaaaacaa agtagaagca tcagcttttc
     9301 ttgaatcata acttaactga agaaattcag ctttttctgg tacatcaaga tgccagcctc
     9361 ttgttgaaac aaattctttt aatagatttt cttttaatag taaatgacgg atgtcttcta
     9421 aagagaagct cattgattga tccctcgctt tattcaattt cttggtttat tatagcacac
     9481 tctttttaat atatcgtttg tttccgctat gacaaaatcc agctttattc aaattttctt
     9541 gacacagggg acaagcggat gagtattttc ataaacaatg aactgactgt aatagatagg
     9601 agaacgaata gtgtctccaa caatccaaaa acataataat tcaaaaagac gataagacta
     9661 ttggtaagta aaagtccttg cggcattgga agccgaaaaa atttgtggaa aataatcggc
     9721 ggtatcgtta taccgccatt tgaggccccg actgtgtaca atgtgtaaac cccaagactg
     9781 aacaaaagac ttcctgaaat cagtgaaaag aaatgtgagg agatcatttc cacttttgga
     9841 acaatctcta aaacaacagg aaaaagcaga cttcccgcta cagtcttaaa aaatactgat
     9901 tttcctaata ggacagcggc tagaagcagc atcataagat tgatgctcca aacagtaact
     9961 gagcgttgga tagaaaaggc cgtttcaact aaatgtccga tggcgcccac tccggcggaa
    10021 gctatatcgt gagggagcaa gaaccaattc aatccaactg tgataaagaa aagacctaaa
    10081 aatataacgg gtagtttttt tatttcttgt gtcattgata tctcctataa atgttagcca
    10141 taaaaggctg tatatttctt tactttacca aaaaaacgaa accgaattca aaaaaacaat
    10201 tgttcttata aaagttatat aaaatcgatt gccagtttct gttttaccaa ttaaaatgat
    10261 agtaatgttt tgtagaaagt tggaatctga ccgatggata atcaaagaaa accagcatta
    10321 gatcaattaa caccgcaaga aaaaatggca cgaggctctg cttggatgac cgccagtaat
    10381 atcatttcaa gattgctagg cgctgtctat atcattccct ggtatgcttg gatgggcgaa
    10441 aatgctaagg ctgccaatgg attattcaat atgggataca atatatatgc attgtttcta
    10501 ctgatctcta cagcaggaat acctgctgcg attgcaaaac aaactgcacg ctataattca
    10561 ttgaatgaat atggcacttc acgacgatta tttatccgtg cattacagat gatgggcggg
    10621 ctaggcctgt tgtttgcttt gttcatgtac atcgcctctc cttggctagc tcatgcttct
    10681 ggtggcggag aagaactgat tccaacgatg cgttctttga gtatcgctgt attggttttt
    10741 ccttgtatga gtgtgatacg agggtatttt caaggcaatc aagaaatgat gccttatgcg
    10801 ctgtcgcaga ttgtagaaca ggtggcacgt attttttata tgctattggc tacattcatc
    10861 atcatgaaag tcatggatgg tgactatgtg acggcggtca cgcaatcaac tttcgcggca
    10921 tttatcggta tgctagcaag tattcttgtc cttttgtatt ttttgaagaa acatcaagcg
    10981 tatacatcgg cgtttattca ctacagcgaa aacaaaataa atattgcaac gaaggaattg
    11041 ttgttagata ccgttaaaga agcgattccg tttattattg tgggttcagg ggtaacgatc
    11101 ttcaaattag tcgatcagtt cacttttatg aagatcatgt ctgcatccac cgagtattcc
    11161 aatgcacagt tactggatct tttttcgatt tttagtgcca atccagataa gttgacgatg
    11221 gtagttattg cattggcaac atcgatcgcg tctactgggt taccgttgat tacagaagct
    11281 gttacgttga aagatcgagt aggtctggca aaattgacaa gcggaaattt acagttgttt
    11341 tcatttttta tgtttccggc gacatttggt gttatgttac ttgcctatcc gctaaataca
    11401 ttattttata caccggattc tctaggaagt aatgtactga tccaagcaag ttttgtagga
    11461 ctcttcctag gactatatat gctagtttcc aacatgctgc aaggaatgtt tgaaaacaag
    11521 gcggcaatta attatttggt tattgggttt ctagtgaaac tccttcttca atacccagcc
    11581 attcgtttat ttgaagtata cggcccttta ttggcgacaa tgatcggatt tgctgtgtct
    11641 tgtaccttga tcttaaagag aatccatgaa gtagcccgct ttaaaccaag ttttgtctgg
    11701 cgcaggacat tgctgatctt tattcttacc ttgattatgc ttttggcttc gtggatcaca
    11761 aagatgattt ttggtgcttt tttaaacgaa gatagcaaat tccagtctct attgttgatt
    11821 cttgtagtag caggtatagg ggctttagtg tatggttatt tagctttgaa aatccgcttg
    11881 gcagaaagac tactaggacc aggaatagcg cgtttacgac ataaattaaa aataaaataa
    11941 gtgaatcaga agagctagat tgatgctctt ttgaaatggg ggaaacgcat gcgtttagat
    12001 aagtttttag cagatatggg acttggcagc cgcaaagaag tcaaaggatt gatcaaaaaa
    12061 ggaacgatcg aagtcaatgg acaagtggtg aaaagcgata aagcgcaagt aaatgaattc
    12121 gaagatgcgg ttacttattt aggagaaatc attacgtatc aaaaagattt ttactacatt
    12181 ttgcataaac ctgcaggagt catttctgct actcaggata atcatgatca aaccgtaatc
    12241 gatttattgg aagaccagga ttatcgggaa gatctttttc cagtcggccg attagataaa
    12301 gacacagagg gcctcttgat tttaacgaat gacggggtgt ttgcccatca gttactatca
    12361 cctaaaaaac atgtggagaa agaatatcta gctgaggtta gcggtataat gacagaagaa
    12421 gatatccgtt tatttgcaga aggactgatt attgatggcg atgagcagac attgccggca
    12481 aaactccaaa ttgatcaagt agatcaagag acagaaactt caattatccg tctgattttg
    12541 catgaaggaa agtttcacca agttaagcga atggtcaaag cagtaggaaa agaagtctta
    12601 tatttaaaaa gaatccgtat gggaaaattt tggctgccta aagatttgaa taaagggcaa
    12661 tatcgaccca tgaccaaaga agagctagaa caagtgagag aaaaataatt gaatggatag
    12721 ctaaaagaat aagcagagta gttgtagcgc catctgaaaa gcagacttgt ccgtctgact
    12781 ttcggatggc ttttttgtga aatttcggct tatttccgta gaagctactt ctggaacacc
    12841 gtttgttcgg aataagggac tgtgacaaga cttttgttac agtccccatt gttccttgtg
    12901 actcagagtt agatagtaag gacacgatct ccctaatact caggccaaaa cgctgaattc
    12961 acaacctctg ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca
    13021 aaatatgagg aactattttc ccgttttttt ctctaatact caggccaaaa cgctgatttc
    13081 acaacctctc ctatactttg tttcattttc cctatacttt gtttatttat tctcattatt
    13141 gaaagcgcta taattacgtt gcgaatgaat cgaaaggggt ttttagatga aaaaacgaaa
    13201 ggggttcaat cattttttta tgaatctatg gcgttataaa gcacttgtcc tgatggctgt
    13261 accgggtatg ctttggatga tttttttctt ttacatacct gtaatggcga atgtcgtagc
    13321 attcaaaaat tttcatattt cagcagatgg gttcttggct agcttgaggg aaagtccttg
    13381 ggtgggttgg gaaaatttca aatttttatt ttcttcggat caagcatttc tcatcactaa
    13441 aaatacaatt ttatataatg tagcatttat ccttttgaat ctgctgatct cagtcgtatt
    13501 tgcaatcatt atgagcgagt tgagaaataa acgactcgtt aaagtttatc aaacgatgtc
    13561 cttactacct tattttctat cttgggtcat tatcagttac tttgtttacg cttttttaag
    13621 tcctgacaaa ggaatattca atcagtggat cactggacat ggaggagaag ctgtcaattg
    13681 gtataatgaa ccgaaatatt ggccgtttat cttggtgttc attggtacat ggaaagggat
    13741 tggttataac agcattattt actttgcatc tgttatggga atcgatccga cttattatga
    13801 agctgctatg gttgatggag ctagcaaatg gcagcagatc aaacatgtga cgataccaca
    13861 acttattcca ctaatgacga ttttaacgat tttagccgta ggaaacattt tccgagctga
    13921 ttttggcctg ttttataaca ttcctaggaa ttccggtgca ttatatgatg tgactcaagt
    13981 tttggatacg tatatctaca atggcctgac atccacagga gattttggta tgacggctgc
    14041 tgcaggactt taccaatcag ttgtcggctt tgtcttgttg atgatcacaa atacgatcgc
    14101 ccgacgtttt gatagcgatt ctgcattatt ctaaggagga aaaaaatgaa aaaaaagaaa
    14161 gtggagagag tccaagtccg ctctttcaat aagacggcta attttttctc taatataatg
    14221 attgcactct ttgctatttc ctgtattttg ccatttatat ttgttatcgc catctctttt
    14281 accgatgagt ccatattgtc gactcacggg tacagttttt ggccagaaaa gttcagtata
    14341 tttggttata cgtacttgtt cgaccagatg caggataaaa ttttccaagc gcttttcgtc
    14401 actgtacttg ttactgtttt aggtacactg atcaatagca cggctacttc tttatatgct
    14461 tatgcgattt cacggtcaaa ctttccattc cgtcgttttt ttaccgtttt ttgtttgatt
    14521 acgatgttgt tctcaccagg gatggtggcc aattatcttg ttatgacaaa tcttcttcag
    14581 ttaaaagata cgatttgggc attgatcttg ccaatggctg tcagtccctt caatattatt
    14641 gtgatgcgca cattctttaa acgttcggtc tctgattcga ttattgaatc ggcacggatc
    14701 gatggagcta gcgaactgcg aatatttgtt cagatcgttt taccgttagc tgttccaggt
    14761 attgcgacaa tcagtttatt tgccgcattg ggttactgga atgactggtt caatgcttta
    14821 ctatacatcc aagatgataa gctagttcca ctacagtatc ttttgatgaa aatccaaagt
    14881 aatattcaat atctgacaca aaattcagga gcaggaagcc aattgacagg cggattagcc
    14941 tcagttccag gagaatctgc cagaatggcg atcgtagtca tctcgacgtt gcctattgcg
    15001 atcagctatc catttttcca gaagcatttt gtcaaaggtc taacaatcgg cggagtaaaa
    15061 gaataaagaa acaaaaatat aaatcataaa attaggagga agaaaaatga agttatggaa
    15121 gaaactagcc tttacaggtg tttcagcgtt gttgttggga acattagcag catgcggagg
    15181 ttctggttct aaagaccagg cagaagctag caattcggac actttgcaga tgtatcaaat
    15241 cggagataaa ccagataatt tcgatcaatt gatggaagta gcaaacaaac gaatcgaaaa
    15301 agagatcggt gtaaaagtca atatcaatta cattggctgg ggcgattacg aaaagaaaat
    15361 gaacgtcatc atttcttccg gggaaaatta tgatatcgcc tttgcgaaca actatgtttc
    15421 caatgcccaa aaaggagcct ttgctgattt gactgaatta gcgcctaagt acgctgaaaa
    15481 agcttataat gatttagatg aagcatatat taaaggaaat ctggtcaatg gaaaattata
    15541 tgctttccca gtcaatggaa atgtctttgc tcaacaagta cttactttta acaaagcttt
    15601 actagataaa tacgatcttt caattgatgg aatccaatct tacgctgatg cagaaaaagt
    15661 cttgaaggaa ttccatgaaa aagaaccaaa cacggcagct tttgccattg gacaaggctt
    15721 caaagtccaa gggaactttg attatccttt agggaatacg ttaccatttg ctattgatct
    15781 ggatggagat gattcgaaaa tcatcaacca atacgataat gaaacgtata tcggactgtt
    15841 acgtacaatg catagctggt acaaacaagg actcattcca agtgacgctg caacgagcaa
    15901 taaggattat ccactagaag gaaatacttg gctaatgcgt ggagaaacac aaggaccgta
    15961 tgattatggc gatacaattt tgacaaatgc agcaaaacaa gaacttgtct caaaagcaat
    16021 tactgttcca ctaaaatcta cagctcaagc acaaatggca aattttgtcg tatcaaatac
    16081 ttcaaaaaat aaagaaaaat cagtagaact tctagggctg cttaacagtg atccagaatt
    16141 attgaatggg cttgtttggg ggatcgaggg agaagcatgg gaaaaagtcg atggttcaga
    16201 tgataaaatc aaattgctag atggttatca gccaaataca catatgtctg cttggaatac
    16261 aggaaacaac aagattctat atacacaaga gtctattacg gatgacatga ttgccaaacg
    16321 tgatcaatcg attgctgatg cagaaacttc accgatttta ggattcagct tcaacactga
    16381 cagtgtcaaa acagaattaa gtaatatttc taatgtcatg aatcaatatt tagatggatt
    16441 gaatacaggg actgttgatc cagatgaaac attaccgaaa ttgaaagacg ctttggacaa
    16501 ggctggctat gataaggtat tgaaagaaat gcaaaaacaa tatgatgagt tccgacaaga
    16561 ataataatga ataaagacaa aggggttgtg acaaaagacg tgtcacaacc tcttgttccg
    16621 aataaacggt gttcaaaagc cagtttctcg gtattaagct aaatatatgt aaaaatgtgg
    16681 aaagccatat tcacaaaatt tttcttacta ctcgaaacta agcggctatt tcacaaactc
    16741 ttggtaaacg gtgttcaatc agctgaccct cggtattcgc tcacaaaacg acaaaatatg
    16801 aggaactatt tttccgtttg tttctctaat aatcaggtca aggtgctgat tgcccaacct
    16861 ttttttgtat aatgagaaag tataaactta atgtttggag gagaagatat gttagggaag
    16921 gttttggaag agttatttat ccggatctgg gtcattataa aactaacctt gtatttctgg
    16981 atatatacat ttgccggcgg gatcatcttt ggattaggtg cggcatggaa aacagtcaat
    17041 gaactatttt atttgtacgg attcgagtat aaagaaatca caataaaaag aggctggaat
    17101 atatataaaa gaaatttttt aagaggcaat ctgctattta gtttattttt atctggtact
    17161 gctttattga gttacaattt atatttatct gttcaaatca aagggctcat ttttttagct
    17221 attgatttta ttttactttt tgccttgctc tgcctatttg ctacttatca atacagtatg
    17281 attttagata gtgaatatac gatctctgtt cctaatctgc taaagctaag ttttatttcg
    17341 gttttttcca gcttttcgtc ttttctaaaa ataattattg gtagcggtat aattttaggc
    17401 gtgacttggc aattcaaagg attgatcctg tttggtgtca ttggtctttt gacggtttgg
    17461 aatggtacga tgacaacaca ttggcgtgaa gaattagata aacagttgga aagttatgaa
    17521 taagtttcgg attctatttt caaaaggaac cttactaaat cgtctgttgc ggaaatacgc
    17581 ggttatcatg atcggtgtaa cgatgactgc taccgttatt tttagtatcc atacttggga
    17641 acaaaatcaa aaacaggcag aaaacatgac aagtgatgcc gttcaaagca caagcagaat
    17701 gctgaatgat aaaacaacct tgagtaggat catcaaaaac cagcttgtag ggaattccga
    17761 aaagatcgaa aatgtgacga cctacttaac aaaacccata gatcagtatc tgatgtatgt
    17821 atacgaacag caaaacagta ccgatgaatt agtttctttc ccaaatcaaa tcaaagatct
    17881 ctacgcaaat tatgaagaac taagtgcgat atatatcgtg ttgaatcaac taccggagta
    17941 ttatgaatct tctagagaaa acaaaggtgg ggaaataaaa aaggggacac caaaattact
    18001 agacgccttt tatatcaagt tgcctatcac acaaggagga gctgagtcag gaagtatttt
    18061 tattggtttt caaaagaaag aactagatat gattttagaa aatctaacgt cattcaatgg
    18121 actctcttta tacatgattt ctggaacgac aaatcgacta tacacattcc atgataataa
    18181 aatagctaaa gaaacgtttg aaagacaaga aatgatcatc acagagagtc tgaagaaaaa
    18241 ttcacaattg ccgattgacg atctggaaaa aaacaatttt gttcaacacc aagaactgtc
    18301 tgatgattat cgtatattag ctgtactaga taaaaaaagt gtaaaaatcg aaacgggaaa
    18361 aaatcttgcc ccgctgatca ttggtatcat tattttagac aatatactgc ttatctttct
    18421 ttataaaaca ttcaaacgat attcacagca agtatctatc gtcatgcagg ccatggatca
    18481 aacagcagca gggaatttag agacgcggat cgacataaca aacacggaat atgaactgaa
    18541 ggaactttca atcggtatca acgaaatgtt ggatagcatc aatcagtttg tagaagacat
    18601 ctacaaatta gaaatcaaac agcaagacgc acatatgcgg gcgcttcaag cacagatcaa
    18661 tccacacttt ttatataata cattagaata tatccgaatg tatgcaatca gcgaaggaag
    18721 tgaagaatta gcagatgttg tgtatgcgtt ttccgctttg cttcgaaaca atacgaatca
    18781 agagaaaacg atcactttaa aagaagaact ggacttttgc gaaaaatatg tctatttgta
    18841 tcaaatgcgt tatcctaatc gagtagccta tcattttatg atcgatcctg atttggaaaa
    18901 gatcgaagta cctaaatttg tgatccagcc attagttgaa aattatttta aacacggtat
    18961 tgattttact cgattcgata atgcgctaag tgtcaaagtc ttgcaggaag gcaaacgggt
    19021 aaggatcatc atcaaagata atggaaaagg gatgactgaa aaacggctaa aacagattga
    19081 agaaaaactg tctcatccta aagtggaact tcacggttct atcggtctgc aaaacgtgaa
    19141 tgaacgttta cgtgccagct tcggcagcag ttattatatg tcgcttgaga ataatgagac
    19201 aggtggactg accgtttcta ttacattcaa ggagggatga gcgtgtatca agtgttattg
    19261 gtagatgatg aatacatgat tttgaatggg ttaaaaaaga taattgattg gcaaagttta
    19321 ggctttcaaa tagtagcaac agcagagaat gccaaagaag gactagctgt acttgaacag
    19381 cgacagattg atttagtagt aacggatgtg acaatgccag aaataaatgg actggaattt
    19441 attgaagcgg ctcaaaaaga acgtcataat tttgaattta tgattttatc aggataccaa
    19501 gaattcgatt atttgaaagg aggtatgcaa ttaggcgccg tgaattattt gatgaaaccc
    19561 gtgaataagt tcgaattggt tgaaagcctc aagaaaatca aaacacggtt agatcagcaa
    19621 aatgaacaaa aaaatcaaca agaaatctat caagaactgt tattcagtca atggttgaat
    19681 gaagaattgg atgaaataag tgaagaagaa ataataggac aaataagtga gaagcagcat
    19741 aggatagtat tgattcaact ggcaagaact catgatactc ttatcaatag atggttgcaa
    19801 gaacggcaac aaatctttta ctatcaacga aattacggag accgtgtatt gatcacgttg
    19861 ttgttggagg cagatgaagt tgatggcttc tgttgttttg ttcaagaaaa ctttcctgat
    19921 caggaatggc tgatcagtat cggggaagag acagattctt tggacaaaat ccctgaaaca
    19981 ttccaacaag cgaaagacaa tctacagttg catcaatttt atggagataa agacgagcat
    20041 gttttttacg cagtacaagc agaaacaaaa gatcaaacca tcgatttttc aagtttcaga
    20101 cgcgtgctgc aaaataaaca attggaagtc gctcaaaaaa tgatcactga tttttttgaa
    20161 cagtttcagt tagcagccat gatgccggaa gatatacgat attccagttt tttactgttt
    20221 atggagattc aacgggaatt gattgatctg gaagatgagg aatatttaca aggaatcgaa
    20281 aaaatccatc aggcaaaaac ggtgcaagaa cttcagcagc tacttctgtc attcatcaaa
    20341 aagcatcaga gacagaaaaa gtacagtgac aatgtggaaa aagtaatcgt aatcctgcac
    20401 cagcattatc aagaaccact tacactcaaa gaagtgtcag aaaacctgca tttaaatgtc
    20461 atgtatctag gacagctgtt caaaaaagaa acgaaaaaaa gtttttcagc ttatttgaac
    20521 catttacgta tggaaaaagc gaaacaactg cttttgcaca gtaatcaaaa catcaatgag
    20581 atagcaagtg agattggcta caacaacacc acgtatttct ctaaattatt caagaaaatc
    20641 gtcggcagat cccctaaaga gtaccgagaa aacagtggag aatcataaaa aaaaaagcca
    20701 atgtaatgaa ataacttata aaaaattgtc tagaaatcta attttgggct gttcttatta
    20761 cttgaggcaa ggcagctttt tcatgacctc tcgataaacg gagttcaaaa gccagtttct
    20821 cggtattaag ccaaatttat gcaaaaatgt ggaaagccat tttcacaaaa tttttcttaa
    20881 tactcgaaac taaacagctt tttcacgacc tctccactaa atggtgttca atcagctgac
    20941 cctcggtatt agctcaaaaa atggcaaaat atgaggaact attttgccat ttgtctctct
    21001 aatactcagg tcagaacgct gatttcacaa cctctcaata aacggtgttc aaaagcttgc
    21061 atctgcggta ataagaccaa ccaaacgaaa aatatgagga tctatttttg cttggctgtt
    21121 cttattactt gatgcaggac agctttttca caacctcttg ttaattatag tttgataagg
    21181 aaaaaggcaa atcttttgct tgatatttct tagggtgagg gatgatccct aattggtaag
    21241 agatcgtgcc gcctttcagc aaatcttgat gggtaaaata taatttcgta tattctctgt
    21301 ccatccgttt gattttatgg ataaattgtt gctgcggccg attaggcgtt gcttcaatcg
    21361 tcaattcctt tccatttgac aaaagcaaaa cagccttgtc aattaatggc ataccgataa
    21421 catattcacc ggttccaggc gtgacaggat aaaatcccag actattgaag atataccaag
    21481 cggccatact tccattgtcc tcatctccag ggtaacccat tggagaatcg tcgaaggtct
    21541 gagtcatcaa ctgtttaagc agtggctgtg ccatttcagg ttgtcctata taactgaaca
    21601 agtaaggata gtgaaaactt ggctggtttg aaatagctaa ttgtccaaat tctatcgcgg
    21661 ccatctcact catttcgtgg atctcaaaac catatcctcc tgggtcaaac gttgggggct
    21721 gattgcacag ctcaatgagt ttttctttat atctctcact gccaccatat tttccgatca
    21781 gtcctgaaaa atcgtgataa acagcaaagc tgctttgcca agcacttcct tctgcataat
    21841 cttgtcccca acgattagct gaaaatggtt ctctgaactt gccatcttta tcttttgaac
    21901 gcataaatcc tgactcatag tcaaagatat tttgatagtt caatgattgc tgctgatatt
    21961 tcttcgtcat ttcctcttct tctagtacct tggcaacttg gctaatacaa aaatcgctat
    22021 aagcatagtc taatgtgtga ttgactgatt cgtggtagtg attaggaaca tagccatatg
    22081 tcaagtaatc ttctgttcct tggcgtccat aatttggatg tttgctttga accgtagcac
    22141 ctttttccat tgccgttaga aattcaggca tcaagtctcg tcggatatct tttacagcag
    22201 catctgcaat gaccgcatcg atcaatgtcc caggcataag tccacgttca tcaggagaca
    22261 gccattttgg caaatagcca ctttctctat agctgttcaa aaaaccttcc agcatttctt
    22321 cgtatttttc tacagcaatc aaagaataaa gaggataaac cgttttatac gtatcccaaa
    22381 acccattatt tgtatagaga acaccaggtt ttatagatcg actagtcgta tcatagtgga
    22441 ttttttgccc actaggatca atttcataaa atgtttgtgg aaataaaaac acccgatata
    22501 aattatgata aaacgtccgc aattgttgtt gatcatggtg tgtgagctgt atacgatcaa
    22561 aataggactg ccattgttct tgactgtgag caaggtaagt ctctttgctt tggttttgtt
    22621 ctagttccag gttataagct gcttgttccg agctgataaa agatgtccca aatcggatag
    22681 tttgtttttt tgtctgttca aaatacaacg ggatcgagtc gctatttttg ttggaaacag
    22741 ctaactcatc aattgttaaa ggatattcaa atctcaatat aaaataaaaa gaaaaatcag
    22801 gatcttctga accagcaaaa tgtgtgattt ttccttccac tgtgtaagga tctataacaa
    22861 agagctgatg gcgtcccgga aaggataaaa gtaaaccgct gtcatttttg ctgtaatcaa
    22921 tagataagat tccgccatac atgctaggta tcaatgtaga acagatgcca taacgtaatt
    22981 gacagatcga cagatgagtc gggcaaaata tactttcttc tgggcggtaa gaactttgag
    23041 catggaaaag ggtgttctcc tgtagttttc cattgatcgg cgtaaacagc atatgactga
    23101 aatcacccat ccaaggactt ggttgatggg taagacggta gccttgaaaa acgcggtcat
    23161 caggatgaaa ccaccagctg ccgttttgat ccgtagtttg cggtgcaaaa taattcatcc
    23221 caaaaggaac gccagtataa ggctggcagt tcccattaga gaaatttggc tgattcgctg
    23281 ttgcatgtct agtatctatt tgaccgatat tcattttatt tctcctttgt tgattgtctt
    23341 ttgatgaatg aaactggaaa tttactatcg gatggtcgat cttttgtctc taaccaagtg
    23401 accaaagcat ctcccgcaag cttacctaac tgttcaaaat cttgtgcgat ggttgtcagt
    23461 ggcgggtcaa caagagctgc tgcttggata tcatcaaatc cgataattga aaaatcttca
    23521 gggatatgat aaccatgctg tctcaagaga ttcatggtct ggatagcgac aacatcgttt
    23581 tcacaaacaa aagcagttac ttcatactta gtgatataag aaagcaattc atctaatgtc
    23641 gcgcttttgt catccagtga agtgtggaaa gtcaaaccag ctttgtccaa tgcttcaagg
    23701 taaccaaggt aacgctgtcg aacggattgt ggatgagtct gcgtaccaaa caaataagcg
    23761 atttttgaat gtccctgttc gatcaaataa gaggcagcaa gcgcaccgcc ttggaaatta
    23821 tcggaaagaa cggtaggaaa aggtaactca tagatttttt tatctaatat gacgacaggg
    23881 aattctttca atgaaagctc aaaaagtaag tcaagatgtt gttctgtatc aagagcataa
    23941 taaatcaatc cgtcaaattc attgattagc tcttttgctg ttttattttg tagaaagtca
    24001 agcgtcgtca tcatgacatc aatctgttta tcttgcatca cagggttcaa tcccttgcta
    24061 aaatcaccaa cagacaaatc agcgacatat ggaagaagaa acagaatccg tcgtgttttt
    24121 gtaggagaag caagaatctg ttccggagaa gcggatttaa cgaaactgcc tttcccgcga
    24181 acgcgataaa taagtcctaa ttgctctaat tcagtcaatg cacgtttgga agtgattctg
    24241 cttactttat aggtacgtga aagttctttt tcagttggta gttggctgtc tacaggtaat
    24301 tcaccagtta aaatagccgt ttgcaaatca ttaaatattg tctggtacaa tggttgagtc
    24361 atataaacac ctcttaatga tatatcatat tcaaataata ccataatgga tgaaaaagta
    24421 aataaaaaga tattttttga aagcgtagac ataattggct gtatgaagta taatctttaa
    24481 agatatatca aatagaaaga aggttttatt agtggtttat aaagatatac caaaatcggt
    24541 gcagaaattt atggaagata tcacacaaaa atgtggggat atccatgcgg actgggcaaa
    24601 gaattttaca gcagcatttg ccaatactct gttgacaaca gtcaaaaagc aaaatgacgg
    24661 aaccaccttt ttattgacgg gagacattcc agcgatgtgg ttaagagact ctactgcaca
    24721 agttcgtcct tatttagtga ttgcaaaaga agatgaggaa ttagctgaca tgatcagcgg
    24781 gttagtcaaa aagcaatttt tttatatcaa tatcgatcca tatgcgaatg ccttcaacga
    24841 agaagctaac ggtgctggcc accaaacaga tcatacaaaa atgaacgatt ggatctggga
    24901 aagaaaatat gaaattgatt ctttatgcta cccaatacag ttggcctatc ttctttacaa
    24961 aaatacagga aaaactgatc aattcaatca atcttttatt gaaggtatca aaaaaatctt
    25021 ggacgtgttc aaaacagagc aagatcatga acactctcct tatacatttg tacgagacac
    25081 gacaagaaaa gaagatacgc tgatcaatga cgggcgaggt gcaaaaacag cttttacagg
    25141 aatgacatgg tctggtttcc gtcctagcga tgatgcttgc cgttatggat atctggtacc
    25201 atccaatatg tttgcggtgg tcgtgttagg ttatgtggaa gaaatttttc aaacgatact
    25261 cgatgataaa gaaattgtac agcaaacaca gaaattgaag aaagagatcc aagaggggat
    25321 tcagaatcac ggacgaacgg ttaatcaaaa agggcaaacg atttatgcat atgaagtaga
    25381 tggaatggga aacgccacag tcatggatga cagtaatgtg cccaatctga tcgccgcacc
    25441 ttacttggga tattgttctg aacaagagga agattatctg caaacaagaa gaacattgtt
    25501 gagtaaagaa aatccatatt tctatgaagg aaagtacgca aaaggaattg gatcctccca
    25561 tacgccagaa aaatacgttt ggccgattgc attagctatg gaaggaatga caacgtcaga
    25621 caaatctgaa aaagagcgga tattgaattt acttgtagca actgacgcag gaacacacct
    25681 tatgcacgaa ggattcgatg tgaacaatcc tgaaaattat acgagagaat ggttttcttg
    25741 ggcaaatatg atgttttgcg aattagtcat ggattacttt gatattagag tagaaaagta
    25801 ggaggtatcg taaatgaaaa agaaagtata tatcatttct catagccact gggatcgtga
    25861 atggtacatg gcttacgaac agcatcacat gcgactgatt gaattgatag acgatctact
    25921 agagctattt gaagttgatc cgtccttcaa cagttttcat ttggatgggc aaacgattat
    25981 tttagatgac tatcttcaag taaggccaga aaaaagacag gcaatccaac aagcaatcaa
    26041 tgaaggaaaa ttgagaattg gaccatttta tatcttgcaa gatgattttc ttatcagctc
    26101 ggaatcgaac gtgagaaata tgctgattgg catggaagaa agccgtaaat ggggaacccc
    26161 tgtcatgtta ggctattttc ccgatacatt tggaaatatg ggacagacgc ctcaattaat
    26221 gaaacaagct ggtatttcag cagcagcgtt tggccgtggt gtaaaaccaa ttggctttga
    26281 taatcaagtt ttggaagcag aaaactattc ttcccaatac tcagagatgt ggtggaaagg
    26341 ccctgatcaa acagcaatct ttggtctgct atttgccaat tggtatagca acgggaatga
    26401 gattccagta gaaaaagaag cagctcttgc cttttggaag caaaaattag cggatgcaga
    26461 acaatatgcc tctacgaacc acttattgat gatgaatggt gttgatcatc aaccggtaca
    26521 aaaagatata tcaaaagcaa tccatctcgc aaatgaactg tttccagatt acgagtttat
    26581 tcattctaat tttactgact atctggaagc agttcaaaaa gatgtgccag aagacttagg
    26641 ctcagtagaa ggagaattga caagtcaaga aacggatggc tggtatactt tagccaatac
    26701 agcatctgct cgggtttact taaaacaatg gaataccaag gtccagcgac agctagaaaa
    26761 tattacagaa ccacttgcga cgatggctta tgaagttagt ggaaactatc cccatgatca
    26821 attagattat gcttggaaga cattaatgca aaatcatcct cacgacagta tttgcggttg
    26881 ttcagtcgat tctgtccatc gggaaatgat acctcgtttt gaaaaagcag atgaagttgg
    26941 aaagtatctt gcacaagatt ccttagaaca gctgaccgca gcaatcgata cgaccggatt
    27001 cccaaaagac agctttccat ttgtcattgt aaatactgca ggaatggata aaactggtga
    27061 agcagaaata accatcgaat tagaaagaaa aagattcgct gaaggaatac ctgaacaact
    27121 atatcaagag ttagaaaatt tgcctaaacg taagtatcat gtagaaacaa aaagtggggc
    27181 cactatacca gctattttat ctgaagaaac tgtccaattt ggttatgatt tgccgaaaga
    27241 ccgtttccgt gtgccatata tggcaagaat gatcaaagtg actttaccat tagaaaacat
    27301 gccagcattt tcttgggaaa cattcgcgct tgtagaaggg gaagcgaaag cagaagaaaa
    27361 ggaaacaatg attcatcaga gtggacgaat catcgaaaac ggccctctac atttgacgat
    27421 tgaaaaaaat ggtaccatta caatggaaga tcgcaaaaac aaacgaaagt tgaataatct
    27481 gcatattttt gaagatatcg gcgatatagg aaatgagtat atctttaaac aacctttctg
    27541 tgatcagcca atcctatcca gtaacaaaga aaactctgaa gtaaaagtat tagtagatac
    27601 accggaaata gcaaaaataa gtattctaca ggaaatggaa atccctgttt ctgcagacga
    27661 gcgtttagaa aaagaacagc agatggttgt ggaatttcgt tatcgaaaag cagaacgatc
    27721 caaagaaaaa cgaatccttc aaataaaaac aatcatgaca atcagaaaag atagtaaaaa
    27781 aatcgacttt gaaacgactc tcgacaatca gatgaaagat catcgcttac gtgtcttgtt
    27841 tcctacaaag ttacatgtgg aacatcacga agcagatagt atttttgaag tggtgaagcg
    27901 cccaaaccat gtgtctaaaa gttgggaaaa ccccacgaat ccgcaacatc agcaagcatt
    27961 tgtcaatatt catgatgaag agtacggtgt aacagtcgga aactttggtt tgaatgaata
    28021 tgaagtaaca gaagacggac aaatcgcagt gacgctactt cgcagtgtgg gagaactagg
    28081 cgattgggga tattttccaa caccagaagc acagtgtcta ggtgagcatc ggttcaatta
    28141 cagcattgaa ctacatggac cagaagaaaa attctctact tatttgcatg catacgcagc
    28201 acagattcct ttttccactc aacaaatcaa acatcatgaa ggaacattga tttcaaaaca
    28261 acaatattta acgataaaaa gtgaaacgtt tgcaattaca gctttgaaac gcagcaagtt
    28321 tagtgataaa gtagtagtaa gaggtttcaa tatgtctagt catttagaaa aattggaaat
    28381 aactaaagac aatggaaaaa ctgtcatatt gaatctgctt gaagaaccaa cgaagcaagc
    28441 ggttgtccca ataatccaac cttatgagat tcggacaatc ggattcgagg aggaaaacga
    28501 atgtatggcg gaatagaagc aggcggaaca aaatttgtgt gtgcggtttc agatggtgga
    28561 gaaattttag aaaaattaag tatccctacc acaacaccag aagaaacatt ggatcaggta
    28621 tttgaatttt ttgatcgtta tgaattgaag ggaatcggga ttggctcatt cggcccgatt
    28681 ggtatcgaca aaacaaaaga taattacgga tacgttttgg caactcccaa aaaagggtgg
    28741 gcacaattcg attttcttgg cacaatcaag gaacgctaca atattcctgc tgcttggaca
    28801 acggatgtca atgctgctgc atatggggaa ttgaagcaag gagcagcaca aggaaaaaat
    28861 agttgtattt accttaccgt gggaacagga atcggtgcag gtgtcgtgat caatgaagaa
    28921 attttttcag ggatcgcaca tcctgaaatg ggacatattt gggtgaaacg ccatccagat
    28981 gaccattatg aaggtacttg tccttatcat aaagattgtt tagaaggatt agcagcagga
    29041 ccgtctattg aggcacgcac agggatcaaa gggcaagatc tgccgcaaga tcatcctgtt
    29101 tgggctattc aggcttatta tattgctcaa gcactgatca actatacgtt gacgttagca
    29161 cctgaaaaga ttattttagg cggtggggta atgaatcagg atcatctcct tcaaaaaatc
    29221 cgtcagcaat ttgttgaatt gatgggtggt tatatggaaa cacctcaagt aagtgaatat
    29281 atcgttcgtt ggggactgcc gaatgaaagt gggattatcg gtagtttgct gttagcagaa
    29341 cacgaacatc aaaagtaagc agacaaatta cacaaaaaga acagagtctt atcattatct
    29401 gctgataaga ctctgttctt ttttatttct attcccataa tccaggtaaa gctttaccga
    29461 ctattttttc ttgagtaaat ggatggatca tgtgcagttc taatgcatgg agcatcagtc
    29521 gttcagctgt tctattttgg tagagagggt ctccaacgat cggatgtccc ttatgagcta
    29581 aatgaactct gatctggtgt gtacgtccgg tttccaaaac acaatagact tgtgtttgtt
    29641 cagaaagtac tttgttgaca gtgacatgtg tcaaggcgct ctgaccattt ttatcatcta
    29701 cgaccctttt tctccgatca tggcgatctc gtccaatttt attggtgatg gtcatatctt
    29761 tggcaatttc tccccatacg atggcttgat atctccgata gatcattttt tgttccaaca
    29821 ttcttccaag tatcggcaag acaaatggat tttttgcaaa taaaacggca ccgcttgttt
    29881 ctttgtccaa gcggtggaca acgtaaggtc gttgctgttt agtgtcgaga taagcagcta
    29941 aatgattgag taaggtactg ttttctgtcg gttcatttgg atgagtcttc attcctgcag
    30001 gcttatccac tataatcaaa tgctcatctt catataaaac acggatgtgc ttcgcatctc
    30061 ctaattgaac ttcttgataa ttataatctg tttcttcgaa taacaatgtg atctggtcat
    30121 tgccctttac ttcatgatgg aacaaagcag gttgttgatt gatccaaacg tttttacgta
    30181 tacgcaaaaa gtgtcgaacc tttctaggaa ctaaccattc cttttcaagc aagtcgcgaa
    30241 ttgttgtttc aggatggttc ataggtaaag tgatcgtgat tttcacaagt gtactccttt
    30301 cagtgcaatt gcagactaat tgtaccattt ttaaaacata tttaagaaaa aacttacatt
    30361 tttctgttca ttcttatgtt actctacttg cactaacgta aaaaaacata ttgaactaca
    30421 acttaagcag gaagaaaaca ctctttcact atggtaaaat aagacgattg aatcaaatag
    30481 acaggagaag aagcaaatgg attttcaaag cattttagaa aagataaaag ctgctttgat
    30541 cagtttttgg cgttggatca gaccatatct cggacaattc catcgatggc gaaagcgcat
    30601 ctggaaaaaa tatcatgtga acaaattgat tttgctgatt ggtttgatct gtgtcttagt
    30661 gacaagtatc tacctcttta ttttagcaaa acaagcaaat gtcgaaacgt taaaatcagg
    30721 attaagccaa tcgacagtca tttatgataa gaaaaacgaa gaagctggca cactgtacgc
    30781 ccaaaaagga acatatgtag aattaaacgc gatttctccc tatatccaag atgcagtaat
    30841 ctcgacagaa gataggaatt tttacgagca tcacgggttt gatatcaaag ggattgcccg
    30901 tgcagcagtc cgaatggtct tgtctggcgg aacatcaggg ggcggaggaa gtacgatcac
    30961 tcagcagctt gccaaaaatg cgtatctgac attagaccaa acgtttgatc gaaaagcgaa
    31021 ggaattattt ttggcaatcg agatcgaaaa gaagtacagc aaagaagaaa tcttgaccat
    31081 gtatcttaac aatgcctatt ttggcaacgg ggtatggggt gtccaagacg cttccagaaa
    31141 gtattttgga gtagatgcaa cgaatgttac gctgtctgag gctgctactt tggcaggaat
    31201 gctgaaaggt cctggtattt ataatccgat cgatcaccca aaaaatgcga atgatcggaa
    31261 aaacacagta ctaagtgtaa tggaagaaaa cggaaaaatc acaaaagaac aagaacaagc
    31321 agaaagccag acagatatca gcgcgtatct taatgacaca tacgataatt cagattctgg
    31381 ttatcgttat ccttattatt ttgatgcagt gatcgatgaa gcagttaacg agtatggtct
    31441 tgatgaagaa gatgtcatga ataaaggcta taaaatctat acagctttag atcaggatta
    31501 tcaaaagcaa ttagaagcta cttatcaaaa cagtgcatta ttcccagcaa atgcttcaga
    31561 tggtgccatg gtccaatctg cttcagtagc tttagatccg aatacaggtg gtgtacaagc
    31621 actagtagga cgaagaggag atcatgtctt tagaggattc agctttgcta cacagatgcg
    31681 tcgttcacca ggatcaacga tcaaaccatt aagcgtatat acaccagcac tggaagctgg
    31741 atacaagcct tccagtatct tgaaagacga accgcaaagt tattacgatg cgcataattt
    31801 tgacgggaca taccaaggag aagtaccgat gtatcaagct gttgcacaaa gtttgaattt
    31861 gcctgctgta tggcttttgc atgagatcgg tttacaaaaa ggatatgata aagcagaaga
    31921 attcggcctg cctttagcaa aatctgataa gtattatggc ttagcccttg gtggactgga
    31981 aaaaggagta tctccattga tcatggcggg tgcttacagt gcatttgcca atgatggtca
    32041 gatgtatacg ccgcatctta tcacgaaaat cgttgattcg actggagcgg tgatcgtcga
    32101 taacacaaac aaaaaaccaa aacaggtcat atcaaaggaa acagccgatg aaatgaccag
    32161 catgcttctt ggtacatttt caaatggaac agcggctgct gcgaatcctg caggttatac
    32221 gatagcaggg aaaacaggaa ccacagaaac taatttcgat gccacaaaag caaatgacca
    32281 atggatgatc ggttacacgc cagacgtagt gatttcgaca tggatgggtt acgaagaatc
    32341 cagcaagctg cactatttgg aagggacaag tggaaatgtt gtcgggaaag tcttcaaatc
    32401 agcggcagaa ggcatccttc cgtatacttc aaaaacagga tttagtgtag cagatgccta
    32461 tgccacagga ggacaagtgg tagctgcaga tcaagttgga aacacaggaa attctaatgg
    32521 agagtctgga aattggcaag ataacttgaa tcaatatggt gaacaagcaa aagaagggct
    32581 gaaaaacttc ggcgatatgg tgaaagaagg cgttcaggga attggtgaag cggctaaaga
    32641 cctctggcgg aaatatcaag gagagtagcc cctttgaaaa cgaataaccc catgttacaa
    32701 tagagagtaa ctactaaaag aaaagagggc ataacatgtc aaacatctac gatagcgcga
    32761 atcaaatcga acgtgagatc cgtgaattac cagaattcaa agcgttgaaa gaagcgtacg
    32821 agaaagtaca agcaaacgaa gaagcacaca aactgttcaa agacttccaa gcgatgcaaa
    32881 tcgaattaca agaaaaacaa atgagtggac aagagttcag cgacgaagat gcaatgaaag
    32941 cacaagaaat ggctgtgaaa atccaatcag aagaagtaat caatgacttg atgcaaaaag
    33001 agcaaggctt cagtacaatc atcaatgact tgaaccgtat catcatgaca ccagttcgcg
    33061 acctttacag cgaataaaac tattttatga aacaacagag ggtgtgaaag agacgttcgg
    33121 ccttgagcga tgacaaaatt gcttcttatt gccgataggc tgtctcttga acaccattta
    33181 ccaagaggtc gtgagcctac cgtttaactc tgagttacaa ggaacaattt caaaaaacag
    33241 cttctcatgt ttgatgacta ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
    33301 tattcagaaa taggagctac gacaaaagtc ttgtcatagc tcctattttt tgtcattcat
    33361 ttttcaagcg gtagaaatag cctttttgag ctaacagttt ttcgtaagta cctatttcaa
    33421 cgatttttcc ttcatcgatc acaacgattt tatctgcctc tttgatcgtt gaaagccgat
    33481 gagccacaat aaaagtagtg ggtgtttctg tcaggtaatt cagggcttgc tggatttttt
    33541 tctctgactg gttatctaaa gctgaggttg cttcatctag caaaatgatt tttggctgac
    33601 gtatcaacgc tcgtgcaatg gagatacatt gcttttggcc accagacagc ttgttgccat
    33661 gttcgcctac taaggtatcc agaccatcag gaagctggtc aatcagtgaa gaaagttgcg
    33721 cagcttcgat gacttcatct aaacgttctt ttgatacgtt tttcaagcca taagtgatgt
    33781 tctctttgat cgaagcggag aacaacaaag tggtttgagg aacaacggct aaataatttc
    33841 gcacacttcg catatccagt tcatccaaag gctgatcatc tagaaaaatt tttcctgaag
    33901 tcggctggat aaatccaatc aataagttaa ggagtgtaga ttttccagag ccagatggcc
    33961 caacaaaagc aattgtttct ccagctttca cctctagaga aaaatgatcg ataatcggtt
    34021 tgagtgagtc cggataaaga aaagaaacat cctcaaaacg aaaatttcca tccaaatgtt
    34081 ggattttttt cttaccgtga taagtttcta catcgccagc aatcaacagt tcgccaatag
    34141 aagtgataga ttccatgcct tttgaaatcg taggaatcag cgtgatcatt ccagaaacgg
    34201 aattgacgat cgtcgtgaaa tacgtctgat acatcacgac atcgccgggt tggatgcgcc
    34261 cttgtaaagc taatatccca gtgaaactca aacaaatcag ctgaaatatc tgaaaactag
    34321 cccagctgac tgatccgaaa acagattgca ggatatctaa gtggaatcct ttttcataga
    34381 tttgagtaaa atgcttattt aagcgagttg tttcgtgttt ttctaaccca tgagctcgag
    34441 caatcggtgc taattcgatc acttcgatca cttttgcaga agtctcttcc atttcttgcc
    34501 tgaagtctga gttggactgt ctgatccttt tacggaaaaa gagagtaacg aatgcggcga
    34561 gaggaacagt caataagaaa aacatgaaaa caacaggact tttataaagc gtgataccta
    34621 aagctacgaa taaattgaca gcgatattta atccgctgac aaatacttga gaggacaacg
    34681 tttggatagc ttctacatca cggatgatct ttgactggat tcgtccagat tgcaattctt
    34741 tttgataagg aatagatagt tcttggattt tcttgataag ggtcgctctt agtccagctt
    34801 ctacttgacg gatcgaagtg ctatggtatt ttacatgaaa ataattcgtc aatatatttt
    34861 gaccaatcag acaagccatc aaaaaagcgt tgaaataaat ggcctgcaac tgagaagaat
    34921 ctttcgatga agctgcattg attacattgg caatagcgat cggcattaac caagatggaa
    34981 gatgtttgat aataaaaaag agtcctgaca tggcaaaacg ccaataattt ccctgataaa
    35041 gatgcagcaa tgtctgaaaa gcatttgcat gatatttttg ataacttttc tgtattcgtt
    35101 cctccataat cttctcctta acaatcttgg taaataaact gcaagtgttc tattgcttca
    35161 ggaacataaa tctcaggagt agcttcaaga gtggcgtaca ttagaggacg ctcatatttg
    35221 atataatgca gtaccgggcg gaaatctaaa cagcccttgc caacaggtac catgcggatc
    35281 tttccatttt ccatgatata gtctttgaga tgaagcgctg taatataacc atgtaaattg
    35341 tccaaggcac ctcggatcac tttttcctga tcagcatgat tttctttatg catcaaattc
    35401 gcacaatcta aaatgatttt taaatttggt gaagctactt catcgattaa acgtttagct
    35461 aactgatagt tatagattgg atgattgatc cctgcttcaa cagcaacagt tacgccaaaa
    35521 ttttctgcat gagcgactaa ttcaatgata gaatttctgg cgatctgata agcttcttca
    35581 gtaaaatttt cttttgtgta accgacagag acactaccgg tttccgtagc aatcatcttg
    35641 gcttgatagg cagagcacag agcaatttgc tgtttgaaag ttgccaatgc ttgtgcacga
    35701 acttcttgat ttttgctgga taggttgata tagcatccta aaatggaaag ttcgatattg
    35761 tttttttgga agtattcacc aaaataggca gcactcccaa gtgtcatgtc agttaattta
    35821 agttgttcag gaaatgcttt ttgtggtgca aattggatat gggacaagtg aagctgtgat
    35881 actttttgaa cgatttcttc acgatttcga acatctaaat cgtgggcacg gatgcctaaa
    35941 tttaatggaa acatctcaaa ctcctttttg taaataatta gcaagaggca gacgggattc
    36001 ttttatcaat tcaacaatta ttcgggcaac tttatcagcg ccttctggac taaagtgggt
    36061 attgtctttt agtccttctg ggtaattttt acaagtatca ggcataagat gcaggtagaa
    36121 tttttttgtc tcttcttttg agaaggtctg gaacaattct tgtgatcttg agaacacatc
    36181 taaaagagga atatggtgtt tctcagcaaa tgcacgcatc gcttttggat agtctccaag
    36241 tatatctgga ttcaatgttc cgttttctaa gtaatctcgt cgcgtcacag atgtcagtaa
    36301 gaccatttgg acgttcgctt tttttgcgca ttcaaaaaat atctgcagat tttttaaata
    36361 gctaccgaag ggaagcgtac ctctttcttc ttggattttc tggtcgttat gtccaaattg
    36421 tacaaataag aaatcattcg gctgaaactg tgaagctaga cgggctaacc ttccttcctg
    36481 gataaatgat ttggtgctgc gtccattctt tgcttggtta ttgatctgga tctcgggtga
    36541 aaaataagca gagatttttt ctccccaacc tgtctcggga cgcttgtttt catctttttc
    36601 tgccgcagta gaatcaccgg caatatggat agtaggcatg ttatctcttc tttcataaag
    36661 gtttataggc aatgaagcag aacagcaaga gaagaagacg gagcaa
//
LOCUS       DAXLPQ010000024        36552 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.024, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000024 DAXLPQ010000000
VERSION     DAXLPQ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.024"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            25..696
                     /locus_tag="ACF3UO_001446"
     CDS             25..696
                     /locus_tag="ACF3UO_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3657482.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="ACF3UO_001447"
     CDS             755..1195
                     /locus_tag="ACF3UO_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657483.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="ACF3UO_001448"
     CDS             1207..1875
                     /locus_tag="ACF3UO_001448"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFD3657484.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="ACF3UO_001449"
     CDS             1939..2562
                     /locus_tag="ACF3UO_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFD3657485.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="ACF3UO_001450"
     CDS             2618..3004
                     /locus_tag="ACF3UO_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFD3657486.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="ACF3UO_001451"
     CDS             3217..4608
                     /locus_tag="ACF3UO_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFD3657487.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5219..5587
                     /locus_tag="ACF3UO_001452"
     CDS             5219..5587
                     /locus_tag="ACF3UO_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFD3657488.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5767..6708
                     /locus_tag="ACF3UO_001453"
     CDS             5767..6708
                     /locus_tag="ACF3UO_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFD3657489.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6777..7508
                     /locus_tag="ACF3UO_001454"
     CDS             6777..7508
                     /locus_tag="ACF3UO_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3657490.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7652..9832
                     /locus_tag="ACF3UO_001455"
     CDS             7652..9832
                     /locus_tag="ACF3UO_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFD3657491.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9852..10334
                     /locus_tag="ACF3UO_001456"
     CDS             9852..10334
                     /locus_tag="ACF3UO_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFD3657492.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10350..11111
                     /locus_tag="ACF3UO_001457"
     CDS             10350..11111
                     /locus_tag="ACF3UO_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFD3657493.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11242..12576
                     /gene="murC"
                     /locus_tag="ACF3UO_001458"
     CDS             11242..12576
                     /gene="murC"
                     /locus_tag="ACF3UO_001458"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFD3657494.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12883..13368
                     /locus_tag="ACF3UO_001459"
     CDS             12883..13368
                     /locus_tag="ACF3UO_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFD3657495.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13361..14044
                     /locus_tag="ACF3UO_001460"
     CDS             13361..14044
                     /locus_tag="ACF3UO_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFD3657496.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14170..16815
                     /gene="polA"
                     /locus_tag="ACF3UO_001461"
     CDS             14170..16815
                     /gene="polA"
                     /locus_tag="ACF3UO_001461"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFD3657497.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16860..17696
                     /gene="mutM"
                     /locus_tag="ACF3UO_001462"
     CDS             16860..17696
                     /gene="mutM"
                     /locus_tag="ACF3UO_001462"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFD3657498.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17660..18289
                     /gene="coaE"
                     /locus_tag="ACF3UO_001463"
     CDS             17660..18289
                     /gene="coaE"
                     /locus_tag="ACF3UO_001463"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFD3657499.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            18341..18673
                     /locus_tag="ACF3UO_001464"
     CDS             18341..18673
                     /locus_tag="ACF3UO_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD3657500.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18985..19476
                     /gene="nrdR"
                     /locus_tag="ACF3UO_001465"
     CDS             18985..19476
                     /gene="nrdR"
                     /locus_tag="ACF3UO_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFD3657501.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19499..20872
                     /locus_tag="ACF3UO_001466"
     CDS             19499..20872
                     /locus_tag="ACF3UO_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD3657502.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20872..21798
                     /gene="dnaI"
                     /locus_tag="ACF3UO_001467"
     CDS             20872..21798
                     /gene="dnaI"
                     /locus_tag="ACF3UO_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFD3657503.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21927..22367
                     /locus_tag="ACF3UO_001468"
     CDS             21927..22367
                     /locus_tag="ACF3UO_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFD3657504.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22511..23212
                     /locus_tag="ACF3UO_001469"
     CDS             22511..23212
                     /locus_tag="ACF3UO_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFD3657505.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23209..24330
                     /locus_tag="ACF3UO_001470"
     CDS             23209..24330
                     /locus_tag="ACF3UO_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFD3657506.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24345..25577
                     /gene="pepT"
                     /locus_tag="ACF3UO_001471"
     CDS             24345..25577
                     /gene="pepT"
                     /locus_tag="ACF3UO_001471"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFD3657507.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25709..26617
                     /locus_tag="ACF3UO_001472"
     CDS             25709..26617
                     /locus_tag="ACF3UO_001472"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3657508.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26652..26924
                     /locus_tag="ACF3UO_001473"
     CDS             26652..26924
                     /locus_tag="ACF3UO_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFD3657509.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26935..27981
                     /locus_tag="ACF3UO_001474"
     CDS             26935..27981
                     /locus_tag="ACF3UO_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFD3657510.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28232..30841
                     /gene="clpB"
                     /locus_tag="ACF3UO_001475"
     CDS             28232..30841
                     /gene="clpB"
                     /locus_tag="ACF3UO_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFD3657511.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30992..31678)
                     /locus_tag="ACF3UO_001476"
     CDS             complement(30992..31678)
                     /locus_tag="ACF3UO_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657512.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31656..32150)
                     /locus_tag="ACF3UO_001477"
     CDS             complement(31656..32150)
                     /locus_tag="ACF3UO_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFD3657513.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32170..33390)
                     /locus_tag="ACF3UO_001478"
     CDS             complement(32170..33390)
                     /locus_tag="ACF3UO_001478"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3657514.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33537..35372
                     /gene="lepA"
                     /locus_tag="ACF3UO_001479"
     CDS             33537..35372
                     /gene="lepA"
                     /locus_tag="ACF3UO_001479"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFD3657515.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(35466..>36552)
                     /locus_tag="ACF3UO_001480"
     CDS             complement(35466..>36552)
                     /locus_tag="ACF3UO_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3657516.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        12166 a         6465 c         7815 g        10106 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
     5221 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
     5281 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
     5341 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
     5401 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
     5461 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
     5521 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
     5581 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
     5641 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
     5701 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
     5761 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
     5821 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
     5881 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
     5941 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
     6001 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
     6061 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
     6121 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
     6181 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
     6241 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
     6301 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
     6361 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
     6421 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
     6481 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
     6541 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
     6601 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
     6661 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
     6721 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
     6781 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
     6841 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
     6901 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
     6961 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
     7021 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
     7081 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
     7141 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
     7201 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
     7261 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
     7321 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
     7381 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
     7441 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
     7501 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
     7561 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
     7621 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
     7681 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
     7741 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
     7801 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
     7861 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
     7921 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
     7981 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
     8041 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
     8101 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
     8161 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
     8221 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
     8281 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
     8341 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
     8401 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
     8461 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
     8521 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
     8581 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
     8641 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
     8701 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
     8761 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
     8821 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
     8881 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
     8941 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
     9001 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
     9061 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
     9121 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
     9181 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
     9241 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
     9301 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
     9361 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
     9421 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
     9481 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
     9541 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
     9601 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
     9661 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
     9721 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
     9781 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
     9841 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
     9901 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
     9961 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    10021 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    10081 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    10141 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    10201 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    10261 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    10321 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    10381 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    10441 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    10501 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    10561 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    10621 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    10681 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    10741 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    10801 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    10861 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    10921 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    10981 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    11041 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    11101 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    11161 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    11221 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    11281 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    11341 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    11401 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    11461 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    11521 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    11581 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    11641 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    11701 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    11761 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    11821 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    11881 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    11941 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    12001 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    12061 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    12121 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    12181 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    12241 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    12301 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    12361 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    12421 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    12481 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    12541 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    12601 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    12661 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    12721 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    12781 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    12841 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    12901 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    12961 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    13021 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    13081 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    13141 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    13201 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    13261 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    13321 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    13381 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    13441 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    13501 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    13561 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    13621 ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata ttggaacagt
    13681 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    13741 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    13801 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    13861 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    13921 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    13981 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    14041 ctaaaaaaaa aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    14101 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    14161 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    14221 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    14281 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    14341 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    14401 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    14461 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    14521 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    14581 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    14641 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    14701 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    14761 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    14821 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    14881 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    14941 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    15001 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    15061 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    15121 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    15181 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    15241 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    15301 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    15361 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    15421 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    15481 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    15541 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    15601 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    15661 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    15721 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    15781 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    15841 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    15901 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    15961 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    16021 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    16081 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    16141 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    16201 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    16261 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    16321 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    16381 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    16441 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    16501 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    16561 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    16621 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    16681 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    16741 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    16801 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    16861 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    16921 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    16981 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    17041 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    17101 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    17161 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    17221 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    17281 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    17341 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    17401 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    17461 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    17521 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    17581 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    17641 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    17701 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    17761 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    17821 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    17881 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    17941 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    18001 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    18061 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    18121 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    18181 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaat
    18241 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    18301 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    18361 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    18421 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    18481 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    18541 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    18601 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    18661 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    18721 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    18781 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    18841 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    18901 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    18961 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    19021 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    19081 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    19141 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    19201 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    19261 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    19321 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    19381 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    19441 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    19501 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    19561 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    19621 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    19681 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    19741 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    19801 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    19861 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    19921 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    19981 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    20041 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    20101 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    20161 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    20221 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    20281 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    20341 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    20401 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    20461 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    20521 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    20581 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    20641 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    20701 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    20761 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    20821 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    20881 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    20941 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    21001 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    21061 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    21121 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    21181 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    21241 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    21301 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    21361 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    21421 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    21481 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    21541 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    21601 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    21661 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    21721 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    21781 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    21841 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    21901 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    21961 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    22021 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    22081 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    22141 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    22201 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    22261 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    22321 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    22381 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    22441 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    22501 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    22561 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    22621 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    22681 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    22741 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    22801 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    22861 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    22921 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    22981 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    23041 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    23101 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    23161 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    23221 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    23281 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    23341 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    23401 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    23461 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    23521 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    23581 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    23641 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    23701 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    23761 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    23821 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    23881 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    23941 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    24001 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    24061 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    24121 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    24181 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    24241 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    24301 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    24361 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    24421 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    24481 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    24541 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    24601 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    24661 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    24721 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    24781 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    24841 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    24901 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    24961 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    25021 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    25081 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    25141 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    25201 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    25261 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    25321 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    25381 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    25441 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    25501 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    25561 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    25621 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    25681 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    25741 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    25801 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    25861 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    25921 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    25981 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    26041 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    26101 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    26161 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    26221 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    26281 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    26341 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    26401 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    26461 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    26521 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    26581 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    26641 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    26701 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    26761 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    26821 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    26881 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    26941 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    27001 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    27061 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    27121 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    27181 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    27241 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    27301 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    27361 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    27421 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    27481 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    27541 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    27601 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    27661 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    27721 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    27781 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    27841 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    27901 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    27961 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    28021 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    28081 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    28141 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    28201 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    28261 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    28321 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    28381 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    28441 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    28501 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    28561 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    28621 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    28681 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    28741 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    28801 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    28861 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    28921 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    28981 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    29041 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    29101 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    29161 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    29221 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    29281 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    29341 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    29401 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    29461 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    29521 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    29581 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    29641 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    29701 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    29761 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    29821 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    29881 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    29941 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    30001 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    30061 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    30121 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    30181 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    30241 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    30301 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    30361 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    30421 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    30481 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    30541 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    30601 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    30661 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    30721 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    30781 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    30841 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    30901 tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg aaatttcttg
    30961 aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt tctaatttat
    31021 aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat cccattaagg
    31081 cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct gctcgtccga
    31141 caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag aactggtcgc
    31201 ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca aagccgaata
    31261 agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag taaccaatca
    31321 atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt ttgtcccaaa
    31381 aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg aacaagaaaa
    31441 accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc aaaatgactt
    31501 gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg attccttgag
    31561 aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg aatacaccaa
    31621 aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt ccctccatct
    31681 aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt tccgttcaat
    31741 ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc tgtttcttgt
    31801 agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt atataagccg
    31861 atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc ggcatcgatc
    31921 gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc tgtgtcagca
    31981 agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc attttcttga
    32041 ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa ctgttggtta
    32101 tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat ctaaacatca
    32161 tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga tacgctctag
    32221 tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat aagaagcacg
    32281 gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg attttcctat
    32341 aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga agacaccatt
    32401 attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg ttccaacaaa
    32461 cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat atggttcgat
    32521 ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt tataaatatc
    32581 tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata agccatttcg
    32641 agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag ctacccagta
    32701 gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg tgcgctcatc
    32761 ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata aagcaccatg
    32821 gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa ctggtaatcg
    32881 ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga ttttaaagga
    32941 aagtttatca gacatgattt cccatccttt acgccgatag taggggatac tgtaaggata
    33001 caaataagag atccattgct tattcttgcg catattatcc aatgcaacga taattagatc
    33061 ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca caccacccat
    33121 tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt gagagatcag
    33181 tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt ttttggaacg
    33241 gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag tcacttggaa
    33301 cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg gttttaattc
    33361 aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta gcttgataac
    33421 agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa ctctttaaat
    33481 tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga gacgctatgg
    33541 atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc atcgctcata
    33601 tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac actgtgacgt
    33661 ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa cgtggaatca
    33721 cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa acatatatct
    33781 ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct cgaagccttg
    33841 ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa gcacaaacat
    33901 tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc atcaataaaa
    33961 tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac gtaatcggaa
    34021 tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt gaagatattc
    34081 tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca ccgctaaaag
    34141 ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat gtccggatca
    34201 cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc aaaacatttg
    34261 atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt ttgatggtcg
    34321 gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga gtaggggata
    34381 cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga aaaatgaatc
    34441 cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat ttgcgggaag
    34501 ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa acctctcaag
    34561 cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat gtcgtccaag
    34621 aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc gttatttacc
    34681 atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat tttcctgaac
    34741 ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg gtcccaaatg
    34801 attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc attacgatgg
    34861 attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct gaaattgtct
    34921 ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg gattatgaaa
    34981 tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat ggagaaaaag
    35041 tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga aaagcaatcg
    35101 ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc caagcagcta
    35161 ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac gtcttggcta
    35221 aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa aaagaaggga
    35281 agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc atggccgttc
    35341 tgaaaatgga cgaggacgaa ccgaagaaat agcaagggtt tgtttgaaaa cagtgtaaaa
    35401 aataaaccat gtttacatgg atttgccacc ggtttgccac cggtggtttt tttcggtggc
    35461 aaaaatcaag aattctttct aagattttcc atgatatcga ccgtttcatt tctcatctta
    35521 tctgttacat gcgagtaagt atccatcgta attgaaattc tgctgtggcc caatcgttca
    35581 gagatttctt tcatttttgc gccattttcg agaagaagtg tagcatgagt atgtctgaga
    35641 gaatggaagt taaaagagag ggagagtgca ttcgatatcc tcctagtatt ccatttcact
    35701 acacttggcg taactagctc accgtcttcc ttcgtacata ctgcatttga atcaatgtag
    35761 agctttccat acttcattcg attttctaat tgttgtttct tatgtttttt cagaattgct
    35821 agcaaggttt gtccaataaa aatcgttcga ttggaactgc ttgtctttgg cgtaccatat
    35881 acccatgcgc cgtcattctt taccatttgt ttctctacag taattgttcc atttgaaaaa
    35941 tcgacatcat cccacgtcag accacaaact tcgccaacgc gcattcccgt ataaaatcca
    36001 atattcaaag gaatatagaa aggatgtcct tcaggagtaa tttctagcat atgatcaaag
    36061 tcctcaagag aaatgatttt tagatctttt ttagtcgttg gtcgtgcttc atattttggt
    36121 atttttacat acagcatagg attttgcttg attaatcccc aaggataaac cgccatattc
    36181 agcgcattct taaggacaga gtgagtaata gtcattgttt tcttcgagta acccttttta
    36241 aattcagcat tgatgaaatt ttgtaaaaga gcaggggaga gatccgtaag ttttttcttt
    36301 cctaaataac cgtttatatg atttttgatg gtaaatcggt agttttcata ggtattgtat
    36361 tttagattta gtttaacgta ttcctccatc caaaaatcaa ggtattgttt tactcgagta
    36421 tccgtaccta aaaagtattg tcctgtttcg tcaatatctg ataaaacttt tcgtaaagca
    36481 gcttcggcct ctggtcgggt gtctccgcca actttctcca ctttttttct tgagccatca
    36541 tcattgatat ct
//
LOCUS       DAXLPQ010000025        33126 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.025, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000025 DAXLPQ010000000
VERSION     DAXLPQ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.025"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(93..950)
                     /locus_tag="ACF3UO_001481"
     CDS             complement(93..950)
                     /locus_tag="ACF3UO_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3657517.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(1058..2361)
                     /locus_tag="ACF3UO_001482"
                     /pseudo
     CDS             complement(1058..2361)
                     /locus_tag="ACF3UO_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(2358..2867)
                     /locus_tag="ACF3UO_001483"
     CDS             complement(2358..2867)
                     /locus_tag="ACF3UO_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657518.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(3042..5177)
                     /locus_tag="ACF3UO_001484"
     CDS             complement(3042..5177)
                     /locus_tag="ACF3UO_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFD3657519.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(5260..6915)
                     /locus_tag="ACF3UO_001485"
     CDS             complement(5260..6915)
                     /locus_tag="ACF3UO_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3657520.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(6917..7231)
                     /locus_tag="ACF3UO_001486"
     CDS             complement(6917..7231)
                     /locus_tag="ACF3UO_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3657521.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            7401..7661
                     /locus_tag="ACF3UO_001487"
     CDS             7401..7661
                     /locus_tag="ACF3UO_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFD3657522.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            7675..7989
                     /locus_tag="ACF3UO_001488"
     CDS             7675..7989
                     /locus_tag="ACF3UO_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFD3657523.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(8719..9273)
                     /locus_tag="ACF3UO_001489"
     CDS             complement(8719..9273)
                     /locus_tag="ACF3UO_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFD3657524.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(9399..11327)
                     /locus_tag="ACF3UO_001490"
     CDS             complement(9399..11327)
                     /locus_tag="ACF3UO_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFD3657525.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(11633..12349)
                     /locus_tag="ACF3UO_001491"
     CDS             complement(11633..12349)
                     /locus_tag="ACF3UO_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD3657526.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(12350..14173)
                     /gene="glpO"
                     /locus_tag="ACF3UO_001492"
     CDS             complement(12350..14173)
                     /gene="glpO"
                     /locus_tag="ACF3UO_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFD3657527.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLIPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(14187..15683)
                     /gene="glpK"
                     /locus_tag="ACF3UO_001493"
     CDS             complement(14187..15683)
                     /gene="glpK"
                     /locus_tag="ACF3UO_001493"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFD3657528.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(15819..17279)
                     /locus_tag="ACF3UO_001494"
     CDS             complement(15819..17279)
                     /locus_tag="ACF3UO_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657529.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(17269..18564)
                     /locus_tag="ACF3UO_001495"
     CDS             complement(17269..18564)
                     /locus_tag="ACF3UO_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3657530.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(18896..19573)
                     /locus_tag="ACF3UO_001496"
     CDS             complement(18896..19573)
                     /locus_tag="ACF3UO_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFD3657531.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(19603..20694)
                     /locus_tag="ACF3UO_001497"
     CDS             complement(19603..20694)
                     /locus_tag="ACF3UO_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFD3657532.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(20795..21229)
                     /locus_tag="ACF3UO_001498"
     CDS             complement(20795..21229)
                     /locus_tag="ACF3UO_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFD3657533.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(21813..23270)
                     /locus_tag="ACF3UO_001499"
     CDS             complement(21813..23270)
                     /locus_tag="ACF3UO_001499"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3657534.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(23267..25162)
                     /locus_tag="ACF3UO_001500"
     CDS             complement(23267..25162)
                     /locus_tag="ACF3UO_001500"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3657535.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(25220..26995)
                     /locus_tag="ACF3UO_001501"
     CDS             complement(25220..26995)
                     /locus_tag="ACF3UO_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFD3657536.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(27045..28541)
                     /locus_tag="ACF3UO_001502"
     CDS             complement(27045..28541)
                     /locus_tag="ACF3UO_001502"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3657537.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(28735..30357)
                     /locus_tag="ACF3UO_001503"
     CDS             complement(28735..30357)
                     /locus_tag="ACF3UO_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3657538.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(30807..32120)
                     /locus_tag="ACF3UO_001504"
     CDS             complement(30807..32120)
                     /locus_tag="ACF3UO_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFD3657539.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(32365..32589)
                     /locus_tag="ACF3UO_001505"
     CDS             complement(32365..32589)
                     /locus_tag="ACF3UO_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657540.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(32609..33031)
                     /locus_tag="ACF3UO_001506"
     CDS             complement(32609..33031)
                     /locus_tag="ACF3UO_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3657541.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
BASE COUNT         9461 a         7107 c         5512 g        11046 t
ORIGIN      
        1 ataactaaag agagatggga catgtagtgg cactcaagaa ttagattttt cagtctaact
       61 tcgaggtact ctaccttccc atcctctctt ttttatttct ttttgcggat gattccgtaa
      121 gctgctgcga ctaacacacc cgcccctgct aaggaataac tgacagaagc tgttttttca
      181 tttgtttttg gcaaagtctg acttgttgat ttggatggct ctgtcgtttg ctgaactgtt
      241 tctgtcgtgc ttccagaggt cactgatttt tctcctgccg aatgcaaaat atcttttatt
      301 cgttggaaac tagctgctaa gtcagctttt tttgcttcaa aatcattagc aactgtttgt
      361 gcttcgctga tctttccgtg gattgcttga cttgccgctg tgatatccgc ttgagtttga
      421 cttagctttc cagaagctgt ttgagcaacc tgatttaatt gctgattgaa ttcttttgct
      481 tgttggatct tcccgtcaag atctgtttgg acagcttccg cttttgcttt cgcttcggca
      541 agctttttct caagttgtgc acggtcattt cccactttat ttttaagatc agctaaatct
      601 tgatcgattg ctgcttggtc ttctttcaat ttgttttttg cagcttctaa tgcttcttcg
      661 agttcttttc ttttattttc caagtcttgc aaatgatcga tttggtcaga agaggtagaa
      721 ctatttattg atgtatcttc tgaagatgaa atcgtttctc ctgaattatc tgtcggtaca
      781 ttggaagtca tttctgtttc cgaggcaccg ttttcagcac cagaagagct tatagttgtt
      841 gaaggttctg tttgagcagg ttcagaagtt tccgcaaaag ctgtctgtcc caataagaaa
      901 atactggaaa cagcaattgg ccagattaac ggcttcattc tttttttcat cacttttccc
      961 atccttacta ctttttaact aatttcttat tataagcaaa aatgtttgga agaaccataa
     1021 acacaacagg ctgtttgtct aaaaaacggt gcatctttta tttttttgta cgttccgggc
     1081 ttttccatgt cccgcttcca taacctaaaa tcgttttgac tgctggaatg aaagtcgtca
     1141 cgatcgttat cgcgttcact atccagaaca aaagcatata tagtggtgcg aaaagaaggt
     1201 atttcaattt tcttcgtcga tcatctacaa tcagcgaagc tagcaactgg aaaaatcctg
     1261 cgaccatttc aaagcagatg aacacaaaac tgaatgtaaa agtaatataa atctgttcgt
     1321 agtttccttg atatacataa tgcccgatta atccagcaaa aagaactacg gaaatacaaa
     1381 agaatattga ccagacaata ctcaatgttt gatcaatgaa gatgatcgtt cttccaatat
     1441 gtttaaaagg atggagcatc acttttttga aattcgtcag ccagacttct gttccacctt
     1501 ttgcccaacg ttttctttgt cgatatagca tcttcaacgt cacaggtact tccatgaaaa
     1561 agataatctc aggagcaaaa acagataacc agtcatttaa ctgatgatcc caagcaatac
     1621 tgatgtcttc tgtcgctcga tcttgtctga atccgcccac atcgatcaag gcttcttttc
     1681 gatacatcgt atttgctcca ctgtacgcat aaagaccacc gaaaacagct gactgtgttc
     1741 gtttaatgat gcccacgata cttgagaatt caaccgtttg agattttgca atcaatttgg
     1801 tacgattttg gacatccata tttgcagtga ccgcagcaat atgtcttgca ccagggcgaa
     1861 tgaaataatt cacataccta atcagtgcat ctggctccgg taccgtgtct gcatcattgc
     1921 ttaaaatcaa tttccctttt gcaaaggcaa gtccgatatt aaacgcgtgg gcttttcctt
     1981 tatttttttc gatccgaacc acacgaagat tagcgtattt tttcatcagt ctagctaata
     2041 tttctggtgt ttggtccgtt gaaccatcgt ctgtcactaa tacctcatag ttgtgataat
     2101 tcaatttcgt catcaaatac tcgattgtat cttcgatcac aatttcttca ttatgggctg
     2161 gcaccatgat cgtgatgaac ggttcgacac tcaagggaac atctacccat tctttttgct
     2221 tatgtttgta taaaaacaca taacaccaga caccaataaa ccatacaaat ccgcctaaaa
     2281 tcggataaga aacgagaaaa aatacataat agacaaacaa gtatctaaga ataaattacc
     2341 tgtatgggtg attgagatca tttcagttcc accccatttt ctttatacaa atctgcaatg
     2401 aatgtcgtat ctagattttt ctcttcggag acagaataaa aacggaccgt ttctctctct
     2461 tcttttgttc caaaacgttc cgtatacact tcttcaagta attcttgtct ttttttcaat
     2521 ttttcatctt catattcaaa agatttattt acttttttgt atagatttcg attgttccac
     2581 ctagtcaata caaatgaggt aatcaggaaa ctgaaaaaaa tcaatacaaa aaagccgatt
     2641 aagaaataca gcattttctt ttctgataaa aaagcgtaca aggaaaaatc cttggctctt
     2701 tctggtctcg ttaatgggaa aaagacccat ataaaaggaa gaacaacgat catccatcct
     2761 aaaagagcca ctaacgtttg ccaaatcttt aaccagtaat taccttttga aaaatactta
     2821 tctttcacca aaattgatgc aacttcttct cttgttactt ttttcatatc ctcacctcac
     2881 gtttttttgt tacgacgtag gagtttacca tacatttcat ttcttttcac ataaagtgtt
     2941 cctaaatttt tcctaagaaa aagaacaaaa catttctcat cagtaaatga aaaatatttt
     3001 gttcttttta tcagttgttc tttttatttt ttatctctta attatgttgc tctttccaat
     3061 acgacaatgc ttttcattcc tctagatatc gccgtgtaca tttgtctgcg tcttctttgc
     3121 tcatctccat cgttttcaaa tggatataag attacatgat caaattccag tccttttgct
     3181 agactcaaag gaatgatttg gcagttttct aatccatatg aatttttttt aatcgattct
     3241 tgtagcgttt gggtttcctc ttctgtttgg gtgataactg ccgctttttc tccttttaga
     3301 gaaaccaaaa tctcagctag tattttcaac aattcttcag aggatcgaaa agagcggtat
     3361 tcgggttctt ttccttgcgg tcggatcgat acgatgtcga tcttctcttg atccacagca
     3421 taggttttga aaagctctgt gattgctccg ctagaacggt aactatttct aagatcatac
     3481 cgatggatcg gcagatggta gtcgtcgaaa caacgcataa tatcagcaaa agtagtggaa
     3541 gaattaaaga ttgcctgatt ctcgtcacct actaaagtaa agtgagtttt tggaaataat
     3601 tcgatcaata gacctaattg tgccagggta taatcttgta cttcatcaat caatagatag
     3661 cgaaatgctg gtacatttac cttttcaaca agtaaatgac gaatagctaa tataatgact
     3721 gcttcatcaa cagtacgtgt gggttgccaa gcataagctg agccatatcg tttttcataa
     3781 attctttcaa acaactgatg ctcatccacc catgccattt cttcgatttg tctggttatt
     3841 tttcgatatt ttttttgtaa aagtttcctt gcataagcta caatactttg ttccgaatca
     3901 tcagaaatca atttaccgaa taattccaac tgcctatctt ctgtcaacga gagtacctga
     3961 ttctgcacag caggactttt tgcttgtttc aaaagatgat tcttccattc gctcatcagt
     4021 gcctttttcg ttgcttgaag cctatcgatc aatttaggat gagcaggaac tttctcatat
     4081 attttttcga tcgttttttt agaaaggact gtttttccat ttttagtaag tccacggata
     4141 aaattcggat gatctaaaaa caaaggatct gattgtttta gattatcgat aaactttttg
     4201 ctacgcaaac gttctgtctg ctccgataca ttttctcccg tgatacgttt gaaataagcc
     4261 tcttcacctt ctatttcctc tgctgaaagc tgtgaaacca gctgtatgat ggttagattc
     4321 agtggatttc tttcacctaa tgatggtagg acattcgaaa tatagtcgat aaaccgatga
     4381 ttaggtgata gaatcagcaa gtcatcggat gtcatcgtat ctcgatataa atagagcaga
     4441 tacgcaatac gctgcatgat agcagaggtt ttaccacttc ctgctacgcc atttaccaag
     4501 atattttgac ttttcacatc ccgaatgatt gtgttttgtt ccgattggat cgtagcagtg
     4561 atagccttca tttcattggt ctcatcttgg cctaagactt ctaataatac gtcatcttga
     4621 atagctacag acgtatcaaa aaacttgacc aaacgatctc tttccaaaag aaattgtcgt
     4681 ctttctttaa taaccgtatc gattttattt tgacgaaccg tataagaaga tggaccaatc
     4741 atgttattgt aaaaaagttc ggcaattggt gaacgccaat cataaacaag attttcatct
     4801 gcatcatctg tgaaatttgc tgtaccgata taaaaggatt cttttggctc attatccaga
     4861 aagtctacaa cgacttttcc aaagtaggga cttttcaata aacgttcgat ctttgctagc
     4921 tgattttctg cgtttttctg tttgatattc atctgatcga tttctctatt tttcatttca
     4981 atcatcgaaa aagtatccag gttatctaag taactgtcaa aattcaatcg aagctcgcca
     5041 gccatttctt tcaacgactg gtttccttct atttttgccg tatccatcga ttcccgcagt
     5101 tcgttttttt tatcaattag cttttgatac acgttcttca gatatgcttc ttctaactgt
     5161 ttttgtgtgt tgaccataca cattctcctc tttttttaaa gtggtggaac cgattagttt
     5221 acctctttta agagtcgaat gcaagctttt taacgagtat catttgttag gatatatcag
     5281 ttcttcaggt cggacagttt gatataaaga aaatgcacca tcaaggtttt ttacgtggta
     5341 gccagactgc ttcaagattc tttccgctag atagctacgt aatccgctat gacagctgac
     5401 gatatattct tgttggctgt ctaattcatt taatcggtcc cgaagttcat tcaaagggat
     5461 atgtttggct tccttgaatt tgcccttttc caattcttct gctgttcgca catctaataa
     5521 aatttttcct tttgctagtt ctgtcggcaa ttcatgccat tgtacggttt cactaagccc
     5581 ttctgcaatg ttcattgctg catatcctag catgtttact ggatctttgg ctgagccaaa
     5641 tggcggtgca tacgtcaatt ctaattccgg taaatcgaag atcgtcaaat gccctttgat
     5701 tgctgttgct aaaatatcga tccgtttatc cacacctttt gccccaacac cttgtgcacc
     5761 ataaatctcg ccagtctctg gatggaagat caacttcagt aaaatatctg ttgcttctgg
     5821 ataatagctt gcatgatctt ttcctgatac atgaatgact tcaaaagaca gttcgttttc
     5881 tttggctgtt ctttcactta aaccggtgga tgcggcagtc attccaaacg ttcgtataat
     5941 tgctgttcca ataccgcctt gatttcttcg agaaattccg gaaatcgtgt ccgcaacttg
     6001 tctaccttga cgattggctg gtgaagcaag agaaataagt gcatcttttc cagtgatttg
     6061 ctgttttaca acgatagcat cccccaccgc ataaatatca ggaatattcg tttgataacg
     6121 ttcgtctact aggatacccc cgcgtatgcc taattcgatt ccagcggtca ctgctagctg
     6181 gttatcagga cgaacaccaa tggataaaat aactaaatca gcagggatgg tacgcccatc
     6241 atccagtcgc aatcgtttcc cgtggtcttc aaatccagcg acagcatgag aagtaatcac
     6301 ttctactcct tgatgagaca attctttttc tataaaagct gccatttctt catccagtgt
     6361 tggaagaata tgtggtgctt gttcgatcac catgacttct aaacctcttc tttttaggtt
     6421 ttctgccatt tccaatccga tgaatcctgc accaacgatc acggcacgct ttggctgttt
     6481 ttctaatgca tgcatcactt tatcgatatc tggtacattt ctaatagaaa aaacattgtc
     6541 ggcttctgtt atccctggaa tcgatggaac aactggtttt gcaccaggag ataaaaccaa
     6601 tgcatcgtac tgttcaatgt gtttttgacc ctcatgtacg acttctaccg ttttgttttc
     6661 gggaaagatg gctgtcactt catgatttgg acgcacatct aaacaaaaac gagcggataa
     6721 tgattctggc gtttggacaa gaagattttc ccgttcactg atttctcccg aaagataata
     6781 aggcaagccg caatttgcaa aagaaacata cggtcctttt tcaaaaacaa cgatttctgc
     6841 atcttccatt aatcggcgaa gccgtgtagc agcagacatt ccacctgcta cacctccgac
     6901 aataacgatt ttcatcttat ttccctccta ctgttcgatc aaaccattga ttcatgccac
     6961 cacgtacatt cactacatca taaccagatt tctttaattc tttagctgct tgtttactcc
     7021 tcatccctga ttgacaaatc acatagacgg tcttttcttt gtctccatca tatctgttta
     7081 tactttgtaa tggaacattt ttagctcctt ttatatgccc gccccggtat tctgcaggtg
     7141 ttctaacatc aagtaacgct ggattttcca aaagcttttc ctttaattct gggactgtta
     7201 tcgattttat tgattgaaat agcaaattca ttttctgcac ctcatttaca tttttataaa
     7261 tacctcatgg ggtatattaa acaggagctt tattaatatg tcaaccagaa tgactcttca
     7321 tttttttcac tactttttat atttgcataa aataccgata aggggtatta tctaattata
     7381 aaaatagagg agaatgtgtt atggagattg ataataaaaa tatcctgaac cgtttgaaac
     7441 gtacagaggg acaaattcgt ggtatccaaa aaatgatcga agacgaaaaa gaatgtatgg
     7501 atgtcatcac tcaattaagc gctgttcgtt ctagtattga tcgcgtaatg ggcatgatcg
     7561 ttgcagataa tctgaaaaat tgctttgaga aacctgatag taatccagaa gaacaagcgg
     7621 ctaaactaga acaagcgatc aagatgatta ttaaaaagta aaggaatgat ttcaatgaaa
     7681 gtcgttttcc atattgatga attagaaaaa tggtcagaaa cagggaaaaa cgtaaaaaac
     7741 ctgataaaag cttctccaga aacgacgatt gtcgtatctg taaatggcat cgcgattacc
     7801 ggttatctag actctgccaa tgcagaattc ttagatttgc aaggagtcgt ttttcacgct
     7861 tgcgccaatg ctatgcgtgc taatcatatt tcagaaagtt ctttacctga acaagtaatc
     7921 gttgtaccag caggtgtcct tgatttagtt gaactgcaat cccaaggtta tgcttatatc
     7981 aagccttagt cagtagaggt tgcgacagaa gtgatcagct tcaagaaatt tcggcttatt
     8041 tttcgaagaa gctacttctg gaaaaccgtg aatcaaaggt tgtgaaaacg ctgtcctgca
     8101 tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcgttt ggttgggctt
     8161 attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa atcagcggtt
     8221 tgacctaagt attagagaaa aaaacgggaa aatagctcct catattttgc cgttttttga
     8281 gctaataccg aaggtcagct gattgaacac cgtttaagga agagattgtg aaaaagtcgc
     8341 ttagtttcga gtattaagaa aaattttgtg aaaatggatt tctacatttt tgcataaatt
     8401 tggcttaata ccgagaaact ggcttttgaa taccgtttaa ggaagaggtt gtaaaatcag
     8461 cggtttgacc tgagtattag agaaacaaac ggaaaaatag ctgctcatat tttgccgttt
     8521 tttgagctaa taccgaaggt cagctgattg aacaccgttt accaagaggt tgtgagccta
     8581 ccatttaact ccgaatcaca agaaataatt tcaaaaacaa cttctcctgt ttttggtttg
     8641 gttggcttat tatcgagaag tagctactgg gagtctattt atcaaaaaaa ggaatgcgac
     8701 ataggtcaca cccctttttt attttctttg aaacatcttt cggtactcga cagcatacaa
     8761 gacaaaagat tgtaaaagac cgtaagtgat gacggcaaaa atgactctca cccacagcgt
     8821 tggtaattct gggaaaagca gcaaaaggat catgccaaca tagatgacag cagtcgctac
     8881 tttgccatac cacttcgctc cacttaattt gatattttta gatagcccga ttaatccagc
     8941 tacaaacata aagccttctt ttatcaagaa tagaccaaac aacagccaaa gccacggtcg
     9001 ataccatgcc atagacaaaa tcagaaaaag ttgtgtcaat ttatctgcaa acggatcaag
     9061 caccttccct aagtctgtta cctgattata tctccgagca atgaccccgt ctagataatc
     9121 agacaaacct gagacaacaa tgaccgctcc tgctatataa aatgactgtc tcagcacaaa
     9181 ataaagataa atcggcagca aaaaaatacg gaatatcgat aaaagattcg gaatcgtttg
     9241 tatttcttta cgccagtctg tgcttaattt cattttatcg ccctacctcc tcagcactct
     9301 tttcttttta ttttagctta cacggggaat aaaaccaatg atttcactgt ttttattttt
     9361 ctttacagcc actgatatta tgagctaatt tgagataatc acttgctgtt ttcatcgttt
     9421 actcttcttt cttcctgtcg tttgcgcatt tcttttacta gtactttatg agcttttttt
     9481 gatcctcgct ctaggtcacg ctgccgttta cgtgttttat aatcgataaa cagactgtct
     9541 aaatcgtaac ctgtcgggta cagatcttct gctgaacgca ccagacgaac acgctgacga
     9601 ggcacgtgga ttattttttt gtctaaatat acatcaatcg tatcttcacc tatatcttca
     9661 taaactaacg cttctttttg gtattcattg acaaatatcc gatcaccttt tgcaaagagc
     9721 tggcgttctt ttttattctc cttcctattt gtaactgctg tcttaggaag aaattctttt
     9781 ttctgtgtcc gataggcttt ttccgccaag taacgctctg cttgatggat caatttcatc
     9841 gacatatcca ttttatgagc aatccacaaa gcttggcttt ctcctgtttc tccaacccgc
     9901 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
     9961 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    10021 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    10081 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    10141 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    10201 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    10261 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    10321 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    10381 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    10441 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    10501 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    10561 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    10621 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    10681 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    10741 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    10801 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    10861 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    10921 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    10981 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    11041 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    11101 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    11161 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    11221 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    11281 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    11341 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    11401 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    11461 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    11521 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    11581 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    11641 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    11701 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    11761 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    11821 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    11881 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    11941 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    12001 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    12061 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    12121 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    12181 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    12241 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    12301 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    12361 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    12421 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    12481 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    12541 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    12601 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    12661 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    12721 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    12781 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    12841 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    12901 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    12961 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    13021 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    13081 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    13141 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    13201 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    13261 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    13321 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    13381 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    13441 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    13501 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    13561 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    13621 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    13681 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    13741 gtatcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    13801 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    13861 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    13921 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    13981 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    14041 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    14101 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    14161 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    14221 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    14281 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    14341 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    14401 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    14461 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    14521 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    14581 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    14641 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    14701 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    14761 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    14821 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    14881 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    14941 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    15001 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    15061 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    15121 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    15181 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    15241 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    15301 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    15361 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    15421 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    15481 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    15541 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    15601 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    15661 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    15721 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    15781 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    15841 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    15901 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    15961 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    16021 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    16081 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    16141 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    16201 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    16261 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    16321 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    16381 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    16441 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    16501 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    16561 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    16621 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    16681 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    16741 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    16801 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    16861 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    16921 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    16981 tagacgagca tcttaaactt taagctttcc tgcaataaaa acaatagaat tttttccaaa
    17041 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    17101 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    17161 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    17221 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    17281 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    17341 tagctcatgt tcttctaact gttcaaacgt ccatccttct tttactgcaa ttgtcagttg
    17401 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    17461 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    17521 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    17581 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    17641 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    17701 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    17761 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    17821 attcaatgtt aattgttctt cccacatctg attgtcgggg cgagaatgat tagccagcaa
    17881 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    17941 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    18001 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    18061 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    18121 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    18181 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    18241 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    18301 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    18361 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    18421 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    18481 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    18541 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    18601 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    18661 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    18721 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    18781 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    18841 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    18901 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    18961 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    19021 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    19081 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    19141 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    19201 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    19261 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    19321 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    19381 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    19441 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    19501 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    19561 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    19621 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttctt caaaaggttt
    19681 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    19741 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    19801 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    19861 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    19921 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    19981 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    20041 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    20101 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    20161 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    20221 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    20281 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    20341 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    20401 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    20461 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    20521 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    20581 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    20641 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    20701 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    20761 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    20821 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    20881 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    20941 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    21001 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    21061 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    21121 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    21181 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    21241 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    21301 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    21361 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    21421 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    21481 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    21541 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    21601 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    21661 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    21721 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    21781 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    21841 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    21901 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    21961 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc ttcgatagct
    22021 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    22081 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    22141 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    22201 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    22261 accccttcca aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    22321 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    22381 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    22441 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    22501 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    22561 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    22621 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    22681 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    22741 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    22801 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    22861 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    22921 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    22981 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    23041 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    23101 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    23161 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    23221 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    23281 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    23341 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    23401 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    23461 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    23521 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    23581 ccccgtttac aggactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    23641 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    23701 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    23761 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    23821 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    23881 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    23941 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    24001 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    24061 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    24121 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    24181 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    24241 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    24301 ctacaactaa taaagtaatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    24361 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    24421 cagctaaaat tgctggaata accgtacttg tatatcttgc tagaatcacg ggcatcccta
    24481 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    24541 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    24601 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    24661 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    24721 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    24781 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    24841 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    24901 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    24961 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    25021 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    25081 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    25141 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    25201 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    25261 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    25321 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    25381 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    25441 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    25501 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    25561 tctgataaat ctccgaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    25621 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    25681 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    25741 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    25801 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaaccaaat
    25861 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    25921 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    25981 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    26041 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    26101 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    26161 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    26221 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    26281 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    26341 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    26401 gcatgatatt ggaaaaaatt gtactgattt gttgaggcaa ccttgcgtgt tggatcaccg
    26461 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    26521 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    26581 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    26641 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    26701 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    26761 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    26821 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    26881 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    26941 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    27001 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    27061 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    27121 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    27181 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    27241 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    27301 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    27361 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    27421 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    27481 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    27541 ttatagacag cgctacgata ataactaaat gcaatataat ctaccgtgtt agcttgcaag
    27601 tactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tatcctgtaa
    27661 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    27721 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    27781 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    27841 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatctcttt ttttgttagt
    27901 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    27961 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    28021 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    28081 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    28141 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    28201 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    28261 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    28321 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    28381 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    28441 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    28501 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    28561 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    28621 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    28681 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    28741 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    28801 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaacagtga acgtctgctt
    28861 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    28921 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    28981 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    29041 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    29101 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    29161 tttcgcattg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    29221 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    29281 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    29341 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    29401 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    29461 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    29521 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    29581 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    29641 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    29701 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    29761 gtccatacga aagccaccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    29821 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    29881 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    29941 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    30001 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    30061 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    30121 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    30181 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    30241 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    30301 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    30361 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    30421 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    30481 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tattcaggga
    30541 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc ctcggtatta
    30601 gctcaaaaaa cggcaaaata taagaaacta tttttttcgt ttttttctct aatactcagg
    30661 ccagaacact gatttcacaa cctctttata aacggtgttc actcagctgt cccttggtat
    30721 tagctcaaaa aacggcaaaa tatgaggaac tattttttcg tttttttctc taatactcag
    30781 gccagaacac tgatttcaca acctctttat ttcacattca atatccacat gaatcccatg
    30841 aatacaaaga acagaccata catgatggga gatacttctt ttcctctttt agctgctaac
    30901 atggtaattg gatagaagat aaaacctaat gcaatcccat ctgaaatact ataagtcaaa
    30961 ggcatgccga tcaagatcaa gaatgaaggg atcgcaatct ctaagtttcc ccattcgatt
    31021 tgtcgcaaag attgtgccat caatactcct accataatca atgctggtgc agttacttgt
    31081 gaagtaacaa ctgatagtaa tggagaaaag aacaagccta acaagaagaa aatccctgta
    31141 gtaatagctg tgatacctga acgtcctcca acggcgatac cagctgatga ttctacaaat
    31201 gcaccaacag gagaagtacc taataaggaa cccgcaagca tagctgttga atcagaagct
    31261 aaagctttcc ctacacgagg catcttgttg tctttcatga aacctgcttg gtttgctaat
    31321 ccaactaaag ttcctgctgt atcaaagaaa gtcacaagca agaatgtcag cactacgacc
    31381 cacatttgaa gagaattgat gtcccctaca tgttttaatg caactaaaaa tgttggtttc
    31441 aaacttggtg ctgcggcaac aatttcagaa ggcattggaa tcaaacctgt gaccagacct
    31501 aaaatcgttg tagctgccat cccgatgaag atgccacctg gtacacgccg aacaagcaag
    31561 atagcagtta cgactaatcc aaaaatcgtc aaccaagtag aaccaacgtt gagtgatcct
    31621 aatcctacta atgtagattc attcgaaacg atgatcccac cttcgctcag accaaggaaa
    31681 gcaataaata gaccgatacc gccagaaatc gcatatttca aatctgctgg gatcgcatca
    31741 atgatcattt cccgcagctt gaagattgtg atcaaaataa aaatcaaaga agcaacgaat
    31801 acgccggcta atgctgtttc ccatggaatc cccattccta aacaaacaga ataagcaaaa
    31861 aaagcattga tcccaagagc aggtgccgtt ccaattggat aacgggctaa tacccccatt
    31921 aaaatacagc cgatcgcact ggctaatgca gtcgcagtaa acactgctcc ttcatccatt
    31981 ccagaagcac ctaatacagt tggatttaca aataagatat aagccattga gataaatgtt
    32041 gtaaatcctg ccagtacctc acgttttacc gtggtgttca atttttctat ttcgaagtag
    32101 gaaagtattt tttccttcat cttccatccc cctaaatccg aacattataa ataaagtccg
    32161 ttaaaatttc gatttattaa taaaacaacg tgttttatca tatactaaaa caaaacataa
    32221 gtaaacaaaa aattcggatt ttaagcaaaa tccgaacgtt ccatctgatt aaatcccttt
    32281 atctcaaagt tcatgaacat tcactttgga ttacaagaat ttctttattg tgttaataaa
    32341 gtttcttcat tctagtctca aaaatcaata gtgtgatttg attttaccat ttcgtttctg
    32401 ttcttctttg atgaattctt ttgtatcgac aggattcaga ttatttagtc cgccaaaacc
    32461 tgtatcgacc atttttcccc agccttttgt cttctttttt cctgatttga gattctttgc
    32521 tcgaagcttc tcactatgtt ttgctcgccg atacttcaaa taaccttcta atcttcccat
    32581 tagatccact gtttctcctc ctttttattc aatcagacga ctcagctttt cctataacaa
    32641 aataattgcc ttcagggtcc gaaaaattga aagtcaagac gccattgttg tctgtgattt
    32701 ctcctggttc ttccatgttc tcgtagatag tttcaaattc atccgtaaaa aatactaaag
    32761 aaggcggtgg tcctaatacc tctggtgaaa acttctgcac aaatactttt gggaatacgc
    32821 ctaattctaa ttcttttgag atgctgagta caatactctt aaattcttct ggcaattcga
    32881 ttgtttcaga aatttctgca ccaatttttt ctacaaagaa tcggcaaatc atctctacgt
    32941 cattgacata aagcatcaca cgtgtttttt gtatcatcgt ttgacccttc tttctatttg
    33001 attttctttc ctgtctataa actgattcca ttatatcacg aaagcgcaaa caccttgtgt
    33061 ttgatactat tcaagaaaaa taaagcaata gtttctagga ttgctttcct ccacaaactt
    33121 ttttta
//
LOCUS       DAXLPQ010000026        32535 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.026, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000026 DAXLPQ010000000
VERSION     DAXLPQ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.026"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            133..507
                     /locus_tag="ACF3UO_001507"
     CDS             133..507
                     /locus_tag="ACF3UO_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3657542.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="ACF3UO_001508"
     CDS             complement(621..1250)
                     /locus_tag="ACF3UO_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3657543.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="ACF3UO_001509"
     tRNA            complement(1384..1456)
                     /locus_tag="ACF3UO_001509"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="ACF3UO_001510"
     tRNA            1670..1743
                     /locus_tag="ACF3UO_001510"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="ACF3UO_001511"
     CDS             complement(1881..2045)
                     /locus_tag="ACF3UO_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657544.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="ACF3UO_001512"
     CDS             2340..3668
                     /locus_tag="ACF3UO_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFD3657545.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="ACF3UO_001513"
     CDS             3870..4703
                     /locus_tag="ACF3UO_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFD3657546.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="ACF3UO_001514"
     CDS             4719..5456
                     /locus_tag="ACF3UO_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFD3657547.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="ACF3UO_001515"
     CDS             complement(5611..6579)
                     /locus_tag="ACF3UO_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFD3657548.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="ACF3UO_001516"
     CDS             6811..7644
                     /locus_tag="ACF3UO_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFD3657549.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="ACF3UO_001517"
     CDS             7678..8517
                     /locus_tag="ACF3UO_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3657550.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="ACF3UO_001518"
     CDS             8543..9103
                     /locus_tag="ACF3UO_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3657551.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="ACF3UO_001519"
     CDS             9302..11023
                     /locus_tag="ACF3UO_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFD3657552.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="ACF3UO_001520"
     CDS             11188..12330
                     /locus_tag="ACF3UO_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD3657553.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="ACF3UO_001521"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="ACF3UO_001521"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFD3657554.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="ACF3UO_001522"
     CDS             14130..14777
                     /locus_tag="ACF3UO_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFD3657555.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="ACF3UO_001523"
     CDS             15170..17815
                     /locus_tag="ACF3UO_001523"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFD3657556.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="ACF3UO_001524"
     CDS             18125..19438
                     /locus_tag="ACF3UO_001524"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFD3657557.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="ACF3UO_001525"
     CDS             19428..20081
                     /locus_tag="ACF3UO_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3657558.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="ACF3UO_001526"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="ACF3UO_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFD3657559.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="ACF3UO_001527"
     CDS             20978..21178
                     /locus_tag="ACF3UO_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3657560.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21432..23111)
                     /locus_tag="ACF3UO_001528"
     CDS             complement(21432..23111)
                     /locus_tag="ACF3UO_001528"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFD3657561.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23113..23325)
                     /locus_tag="ACF3UO_001529"
     CDS             complement(23113..23325)
                     /locus_tag="ACF3UO_001529"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFD3657562.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23718..25448
                     /gene="efrA"
                     /locus_tag="ACF3UO_001530"
     CDS             23718..25448
                     /gene="efrA"
                     /locus_tag="ACF3UO_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFD3657563.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25445..27205
                     /gene="efrB"
                     /locus_tag="ACF3UO_001531"
     CDS             25445..27205
                     /gene="efrB"
                     /locus_tag="ACF3UO_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFD3657564.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27300..27497
                     /locus_tag="ACF3UO_001532"
     CDS             27300..27497
                     /locus_tag="ACF3UO_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657565.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27650..28135
                     /locus_tag="ACF3UO_001533"
     CDS             27650..28135
                     /locus_tag="ACF3UO_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFD3657566.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="ACF3UO_001534"
     CDS             complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="ACF3UO_001534"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFD3657567.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29012..29533
                     /locus_tag="ACF3UO_001535"
     CDS             29012..29533
                     /locus_tag="ACF3UO_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657568.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            29630..30367
                     /locus_tag="ACF3UO_001536"
     CDS             29630..30367
                     /locus_tag="ACF3UO_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFD3657569.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30371..31288
                     /gene="miaA"
                     /locus_tag="ACF3UO_001537"
     CDS             30371..31288
                     /gene="miaA"
                     /locus_tag="ACF3UO_001537"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFD3657570.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31290..32519
                     /gene="hflX"
                     /locus_tag="ACF3UO_001538"
     CDS             31290..32519
                     /gene="hflX"
                     /locus_tag="ACF3UO_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFD3657571.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVNRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5522 c         6875 g         9366 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaaactttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggcgatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gatcgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattgg ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtag taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg tatttttttg tatgaaaaag
    21301 taaataaatt taagaggcta tgaaagagcc accttgtatc aaggaataag aacaaacaaa
    21361 aatggcttct catgtttttc atttgttttc tcttatattc aggacaaggt gctgatttca
    21421 taacctctta tttattcttc atctggtgtc attaccattg gcaaaatcat tggatgtctt
    21481 tctgtacgtt cgaataagaa aggctgaagc gcgccagtca tcgcttcttt caatttatat
    21541 tctgaacagt caggtccatt caaacattct cttaaagcgt ggaataagat tcgctgagct
    21601 tcattgatca tttctcctga ttctcgcatg tagacaaatc cacgagagag aatatctgga
    21661 ccagccaaga tttctttttt cttgatatcc actgtcgcga cagctaatac aagaccttct
    21721 tctgaaagca ggtgacggtc acgtaaaacg acattaccaa tatcaccgat cccgctacca
    21781 tcgatataca catctccagc cacaaaatgc ccagcaggac gcgcagaatc gctagttaac
    21841 gctaaaacat cgccattttc catgatgaag cagttttctg caggaacacc tacatcttgt
    21901 gctagagaag catgtacttt caacatgcgg aattctccgt ggacaggaat aaaatatttt
    21961 ggcttcatca aacgaagcat taatttttgt tcttcttgtc caccgtgacc ggaagtatgg
    22021 atgttattga tttttccgtg aatcacttct gcaccagctt cagacagcaa attgatcaaa
    22081 tgattgacac ttgttgtatt accaggaata ggtgaacttg aaaagatcac tgtatcgtct
    22141 ggctggattt ggatttgacg gtgagtacca ttcgcgatgc ggctcaacgc ggccatcgct
    22201 tctccttgag aacctgtaca taggatcatc gtttcattgg caggcaagcg attgatttcg
    22261 tgtgcatcta caaatgtgcc gtctggaact ttgatatatc ctaaacgttg accgttgacg
    22321 atggcatttt ccatgcttcg tccgaaaaca gcgattttac gaccagttgc cacagcggca
    22381 tctgctgctt gctgcaaacg gaagatgtta gaagcaaagc tggcaaaaat gatacgtcct
    22441 tcgatttttg aaaagatctt caaaatagaa tgcccaatcg ttttttctga tttagtaaat
    22501 gttggaatct cagcatttgt actatcagat aaaaggcaca agactccttc ttccccgata
    22561 cgagccattt tatgcaagtt tgctggttcg ccaacaggag tgaaatcgaa tttgaagtct
    22621 ccagtcgcta cgatatttcc agaaggtgtt ttcaccacga tccctaatgc atctgggata
    22681 ctatgggtcg ttctgaaaaa gctgacagaa gtctttctaa aacggatgat cgtatcttca
    22741 ttgatctcat ggagctctgc atctcgaagc aagccatgct catctaattt gtttgtgatc
    22801 aacgctaatg cgagaggacc agcatagata ggaatatttg cttgtttcag caagtagggt
    22861 attccgccga tgtggtcttc gtgcccgtga gtaatcacca aggcttttac tttgtgtaag
    22921 ttttgtatga tgtagctgta gtcgggaatg acatagtcaa ttccaagtaa atcgtcttcc
    22981 gggaatttga tcccggcatc aatcaaaatg atttcatctt ggaattgtac cccatacgta
    23041 tttttcccga tttcacctaa tccaccaata gcaaagacgc ctgtctcgtt atttttgatg
    23101 gaaagtttca tattaaaact ccactaatga gaaatcagca ttttcttttt cgtactctag
    23161 atgacttcct tctagaagtt gaacgaattc aatattgtat ggggtatttt cttccacacg
    23221 ttggcgagcg tctacatcgc tttttgcctc aatgtaaaga gattttgttt cttcccgttt
    23281 agggttgcgt acttttgttt cttgataata aactttatag atcattgttt tgtctccttt
    23341 atctgcgtaa agcagtgatt tagctagttg atttttttag acaacacaaa acgaggggac
    23401 aagccacctg gtttttcata tgctttgact agaatactgg attcgagtca aagagacaag
    23461 cctcgttttt gcttatctgt tcggatattt tttcaaccgt accttctgta taaaaaatat
    23521 acaacaatta attgttattc tagcataaaa cagcaaataa gtatagaaat caactagatt
    23581 gaaagaaaaa atcaatgttt atcatcccgc tataatcata atgacttttt tatgagagaa
    23641 gtgttctatt aataggctcg ttgtgctatc atttttagta atgaaaatgt aacaaaagat
    23701 taaaaggaga tgagaaagtg aaactaatgt ggcattatac catgcgttat aagaaattct
    23761 tgtttttcaa tttcatatgc gtatttggtt ttattttgat tgaattagga cttcctacga
    23821 ttttagcacg tatgatcgat gtaggaatcc gcaatgatga ttttgattat gtgaagcaac
    23881 aagggatatt tatgatcgtt attactgtaa tcggtattat tttgaatatc ttgttaggtt
    23941 attttggttc gaggattacg actaatatcg tagcagatat tcgagatgat ttgttcgaaa
    24001 agatccaaag ttattcgcat caggaatacg aaaatctagg cgtatcttca ttgatcactc
    24061 gtacaacaaa cgatgcttat cagatcatgt tgttcctgca aaatatttta cgtatcggtt
    24121 ttatggcacc aatgatgttc attgtcagtt tgtacatggt catgcgtaca agtgtgacac
    24181 tcagtttgta tgtagtaggt gcattacctt tactattatt ggcagtcgta gcgattgcta
    24241 aggtgtctga accgttatct aaaaagcaac aaaaaaactt agataaaatc aacagtatct
    24301 tgcgggaaaa tctttcagga ttgcgtgtga ttcgtgcatt cgtcaatgaa aagtttgaag
    24361 aaaaacgttt tgctgtagtc aatgagaatt atgcttctag ttcaaaaagc ttattccgtt
    24421 tgatggctgt tgcacaaccg ggtttttatt tcttatttaa tatcgtaatg gtattgatca
    24481 tctggagcgg ggcagtgcaa atcgatgcag gcgagcttcg tgtaggagat ttgattgcgt
    24541 ttatcgagta tatattccat gccttgttct cattcatgtt atttgctagt gtgttcatga
    24601 tgtatccaag agcagctgtt tcagctggac gtatccaaga agccctagat gccaaacctt
    24661 cgattgtaga agatccaaat ggtatatctg atacaaaaac taaagggtat atcgaatttc
    24721 aaaatgtaac atttgcttat ccaggccatt cgcaagagcc agtgatacga aatgtcagtt
    24781 ttacagcctc tccaggagag accgttgctt ttattggaag taccggtagc ggaaaatcta
    24841 cgttgatcca attgatccct cgcttttatg atgtgagtga aggaaagatc ttgatcgatg
    24901 gagtagacgt gagagattat cggctaagca agttgcgaga taagattggg tttattccgc
    24961 aaaaagcgct gctatttact ggaacgattg cagataattt gcgatacggg aaagaagatg
    25021 ctacgcaaga agaaatggaa cgtgcagctg agattgctca agcttcagaa ttcatttctc
    25081 gaaaaccaga tggatttaat gaacatttat cagaaggtgg ttccaatttt tcaggtggac
    25141 aaaaacaacg attggcaata gccagagcca tcatacgccg tccggaaatc tatatttttg
    25201 atgacagctt ttctgcatta gattatcaaa cggatgcgaa gttacgtgct cgtctgaaaa
    25261 aagaaacgac agaatctact gtattgatcg tagcacaacg tgtgggaacg atcatgcatg
    25321 cagataagat catcgtatta aatgaaggag aagtcgtcgg tatggggacg catcgggagt
    25381 tgttggaaaa atgcccgatt tattatgata ttgccgcttc tcaattatca aaggaggaat
    25441 tagcatgaaa aaaacctttt cttccttaaa acgtttagct cgatatatca gaccgtatcg
    25501 tgagactttt cttttagtga tcctatttac agttctgaca gtggctttca acgtggcttt
    25561 gccatatgtt acaggacttc ctactacaga aatcagccgt aatattgcca atggcgaatc
    25621 aatcaatttt tcttatatat tcaaatgtct catttggatc acagttgttg gaatagggta
    25681 ttgtatttcg caattacttt ctggtgtttt gatgacaaat gtcgttcaaa gtgccatgca
    25741 tgatttgaga agagacatag aagaaaaaat caatcgtctt ccggtttcat atttcgataa
    25801 aaaccagcaa ggaaatattt tgtctcgtgt gacgaatgat gtagatgcag tcagcggtgc
    25861 tttacaacaa gcttttattg gtatcgtaaa tgcgatattg ggaattacgt tggctgcagc
    25921 aatgatgttt tatatccagc cgatgatggc gctgatctct atgatcatga ttccaacatc
    25981 gatctggatc tcaaaacgag tgatcaatgc ttcgcagaaa tattttcaaa gcatgcagaa
    26041 ttctcttggt gagctaaacg gctacgtcca agaaaatatg acaggtttta gtgtattgaa
    26101 agtatatgga cgcgaaaaag aaacattgga aggattcaaa aaagttaatc acagcttgaa
    26161 atactttggg tttcgtgcag cattcatttc tggcttgatg atgcctctag ttcaattaac
    26221 tgcctatgct acttatattg gtatggctgt tctaggaagc ttttatgtta ttactggggc
    26281 gatcgttgtc ggtcaactac aagcattcat ccaatatatt tggcaaatca gtcagccaat
    26341 ggggaacgtg acacaattgt cttcagtttt gcaaagtgca tcagcggcaa cgaaacgtgt
    26401 attcgagatt ttagatgagc cagaagaaaa agaaaacaaa gtagatgctt cactgccaga
    26461 aacgatttta ggagatgtga cattcgatca tgtcgatttt gcatatgatc cgaagaaacc
    26521 attaatccaa gatttgaatt ttgaagtgaa agctggtcaa accgtagctg tggtcggtcc
    26581 gaccggtgcc ggcaagacga cattgatcaa tctattgatg cgtttttatg acgtagacaa
    26641 aggagcaata aggattgatg gaatcgacac caaatcaatg agtcgcagtg atgtgcgttc
    26701 gctatttggt atggtcttgc aagatgcatg gctttatcaa ggaacgattg cagataatat
    26761 ccgcttcgga aagcttgatg cgacagatta tgaagtagtt gatgctgcga aaacagcaaa
    26821 cgtagatcat tttatccgaa cgatgccaga tggatatgat atggccatca attctgaggg
    26881 agacaatgtg tctttaggac aaaaacagtt gctgacgatt gcccgagcag tggtctccga
    26941 tcctaaaatc ttgattttag atgaagcaac aagttcagta gacacccgtt tagaagcgtt
    27001 gattcaaaaa gcaatggatc gcgtgatgga gggacggaca agtttcgtca tcgctcaccg
    27061 tttatcgaca atccgtgatg cagatctgat tctagtgatg gatcaaggtc agatcattga
    27121 aaaaggaacg catgagagtt tattggcaca aggtggattt tatgaaaaac tgtataacag
    27181 ccaatttgct gaggaagcag aataagtcat ataagaataa aacagtttaa aacttatttt
    27241 ttgttctcta ttcttgataa tggtaaagta aagttatcaa gaaaagtgag gacacggaga
    27301 tggaacagtt tttaaatgaa aaaattactg aagccaaaag agaagttgat cgtttaacgc
    27361 acgtctgtca gacgaagcct tttgattcag ctgatttttt tgaaaatgag tttcaaatcg
    27421 aacgcttggc agcacaaata gaagtgtacg aattaatttt aaaaaaagta atagaagaaa
    27481 atatagatgt acaataaaaa caggtaaaac gtcagttacc agatactgta aatagacatc
    27541 tggcctgagc aggttttacc tgtttttttt cttatgaaat aaatatatgc tatgatacct
    27601 ttattcaata ggattagttt ctacaaaaaa tgaaaggaga aaaataaata tggaacggtt
    27661 tatagcatca aatgccacag tgattggtga tgtgacattg tcagaagatg tgacgatctg
    27721 gtatcaagct gttttacgcg gggacagtaa ttggataaaa ataggacaaa gaacgaatat
    27781 ccaagatggt acaatcatcc atgtcgatca tgatgcacct gtagatattg cggagaatgt
    27841 gacggtagga catcagtgca tgctacatgg ctgtacaatc gaaaaagggg cgctgatcgg
    27901 gatggggacc acgatattga atcatgcggt tattggtgag aatagtttga ttggtgctgg
    27961 atcattagta acagaaggaa aagttattcc tcctaatgtc ttggcttttg gtcgcccagc
    28021 taaagtgatc cgtcctttga caaaagaaga aatacaaaaa aacaaagaaa acatccagca
    28081 ttatgtcgag ataggtcgga tgcatgcgca aggaaaattc aaggagcaaa gataggcagt
    28141 agcatccata aaataaaaaa ggatggtcag tttgagttga ccatcctttt ttatttggtt
    28201 tagataagag agcttaaaaa agcttccttt gaaacagatt aatttaatga agaactgttt
    28261 tccatgactt catcgatcaa tccatatgct tttgcttgtt cagctgtcat atagttgtca
    28321 cgatctgtat ctttttcaat cacttcaagc ggttgtccag tgcgttcagc taaaattttg
    28381 tttaagcgtt cgcgtgtttg caaaatatgg cgtgccgcaa tttcgatttc agttgcttgc
    28441 ccttgagcgc cgccaagagg ttgatggatc atgatctcag catttggtaa agcaaatcgt
    28501 ttaccttttg taccagctgt cagcaagaag cttcccattg aagcagccat acccataaca
    28561 attgtttgga catctgcttt gacaaagttc attgtgtcgt aaatagccat acctgctgta
    28621 actgaaccac caggagaatt gatataaaga tagatatctt tttcagaatc ttgagcgtct
    28681 aagaaaagca attgggcgat gatcgaatta gcaagatcat ctgttacttg gccgcttaac
    28741 atgatgatac ggtctttcaa taaacgtgag tagatatcgt aagctctttc acctcgtgaa
    28801 gattgttcaa tgactgtagg aattaaattc ataatagagt tcctccttga tttcgtttag
    28861 aaatagtgta ccataattta gtttctaata cctaaaatgt agtatacatt tttggtcaaa
    28921 aaaggtcaaa taaaaaactt aggcaaatta gtcgcataaa cccgctttat ggtatgataa
    28981 gcagagaaac aaaacaagga ggaacaacag attgatagtt ggtattactg gccttatcgg
    29041 agtgctgaca ggtgctgtag ttgtctatat cggcatgata ctgcaaatgc gtcacttgga
    29101 aaataaagaa cagcgtagac gtgaattgga attgaaagtc aaagaaatcg agacgctgaa
    29161 tcaattaaat aaaaagatca acgagatctt gcaaaaacgg acaacgctga tggaagaata
    29221 tgtcagcttt gatgcatttg atgattgtta tatcacgatt gacgattttg cgtatctcca
    29281 atcattttca gcgcaaaata gtttttatct gccaaattat attttagacg agctatttaa
    29341 gaatatctcc catcgaaaag tgattttatc tccagatgaa acaatgaaga ttggtggata
    29401 tgcttataaa ggcggacgcg tgattttaga gaattttacg gatagtctga ctgaaatgat
    29461 caatgaaaaa aaagctcagt tgaagactat gacgcgccag ccgattggtt tcttctcgaa
    29521 agatgatgtt tgaagctgat attttgaagc attgccgttg cacatgagag cgtggtaatg
    29581 ctttcttttt ttcttaatga tacaatagaa ctgaacggag tgaagaaaga tgttacaaat
    29641 ctatgcccat cgcggaagca gcggcaccca cccagaaaat acgcttcctg catttgcaga
    29701 agctgtacga gtaggtgcag atggtatcga actagatgtc catctaagca aagatggtta
    29761 tttgatcgtt atgcacgacg aagaagtgga ccggacgact aacggtaaag ggctgattcg
    29821 agaaaaaaca ttggaagaac tcaaaaaatt gaatgcaggg ggcaaattca gcaaagaatt
    29881 tccagcagct aaagttcctg aattgagaga agtgttagga ctgctcctcc aaaaaaatta
    29941 ccgagggatg ctaatgattg aaattaaaac tgatcagtat gaatatcccg gtatcgaaga
    30001 aaaattagcc gaaacattaa aaagtagaga ttggcctttt caacatgcat attgcagctt
    30061 tcatttggat tctttggaaa aaatcgcatt actggaaccg gagatacagc tggacttatt
    30121 gatgagtact tctgataaaa agatccaact agcagcagaa accccttata tagaaggagt
    30181 acatccaaaa aatacttggt tgttcgaaca tccagtccag gcagctgatt ttccaaaagc
    30241 aattcgtgca tggacgatta acgatgaaga agaaatggcc aaatgtcaag aactcaaaat
    30301 agatggaata ataactgatt ttccggagaa agctcttcgg tggaaacaat caacgaaaag
    30361 taggtaaaat atggaaaaag tattagtgat cgtcggtccg acagcagtcg gtaaaacagc
    30421 gctaagtgtg gaactcgcac aactatttgg aggagagatc atcagtggtg attcattgca
    30481 aatctataaa aatctggata tcggtacagc aaaaatcaaa gaagaagaga tgaataatgt
    30541 tccgcatcat ttgattgatg tgatcgaacc tactcaacgt tactcagccg ctgattttca
    30601 gcattcaggt cgacaattga ttaccgagat tgcgaaccga gggcacctac ctatcatagc
    30661 tggtggtacg ggtctctata tccaatccct tctatatgat tatcagttag gagcgacaga
    30721 agaagcgaat cctgagatta gaaaaaagta tgaaacgtta gctgaaacaa ttggttccca
    30781 agcattatgg aatcagttga aagaaaaaga cccggcagct gctgagaaaa tccactggaa
    30841 caatcaacgc aaagtgataa gagctctgga agttttagag acgacaggac atagtatcac
    30901 ggcacctaaa gaagagccaa agcaattgta tgattacctc atgattggat tagatacgaa
    30961 gcgtagtatt ctttatgaac gaatcaatca aagagtcgat ttgatgctag cagaaggttt
    31021 agtagcagaa gcgcgtaagg tgtatgagct tggagaagtc caggccagtc aaggtattgg
    31081 atataaagaa tttttccctt attttgaagg gaaagaaaca ttggaagaag caacagaaca
    31141 agtcaaacta cattcgagaa gatacgcgaa acgtcagttg acgtggtttc gtaaccgttt
    31201 ggatgcacag tggtttgatc ttataagtga gccaaatcaa aaaagtcaga ttgagcaaac
    31261 aatcaaaaaa tggctggagg cggaataaaa tggaagaaaa agtgatcatc gtaggggtag
    31321 aaaccgaagc aaaccagcgt tacttttcag agtcaatgga agagctagtt cagctgacga
    31381 ataccgcatc aggagaagtc gtattcacaa ttacacaaaa gagaccacaa gtgaatcggc
    31441 aaacgattat cggtaaaggg aaattacaag aattagttca acaagcggat gcgcatgaag
    31501 cggatttgat catctttaat catgagctaa ctccgagaca gagccaactg attaccgatg
    31561 ctgttggtct tccggtaatt gatcgcgtgc agcttatctt agatattttt gcgatgcgtg
    31621 ctcgttcgaa agaagggaag ctgcaggttg aacttgctca gttagaatac ctgctgcctc
    31681 gtttagtagg gcaagggaaa acattatctc gtcttggcgg tgggatcgga acaagagggc
    31741 caggtgaaac aaagttagaa acagaccgcc gacatatacg gaataaaatt tttgctgtta
    31801 agaaagaatt gaaagaagta gaagctcatc gagagcgcaa tcgccaaaaa agaaaaaata
    31861 gcgagatttt tcagattgga cttattggct acacgaatgc cgggaagtca actatcttga
    31921 atctattgac acaagcggat acttattcga aagatcaatt gtttgcaacg ttagatccat
    31981 tgactaagag atggcgtttt gctgaaggat ttgagattgc tgtaacggat accgtcgggt
    32041 tcatccaaga cctgcctacg caactgatcg atgctttcca ttctacatta gaagaaagtc
    32101 aaaatatgga tcttttgcta catgtagtcg atgctagttc tccagatcgt attttacagg
    32161 agcagactgt cttaaaattg atggatgaac tgaatatgaa agaaatgccg atactgactg
    32221 tttacaataa ggcagaccag atcgacccag cgatgttcac gcctacgcta ttcccaaatg
    32281 tattgatttc tactcagacg aaagaaggta agatggcgtt gatcgaagca atcaaacgtc
    32341 agctgatgga actaatgacc ccttatacac tttctgtgcc aagcaacgaa ggacagaaat
    32401 taagcgagtt gagaagacaa acaatggttt tggacgaagc gtacatggaa gaaacaaacg
    32461 aatatgaagt taaagggttt gcaaaaacca attcaaaatg gttaagaaaa aaccaataaa
    32521 attttatttt tttaa
//
LOCUS       DAXLPQ010000027        30956 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.027, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000027 DAXLPQ010000000
VERSION     DAXLPQ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.027"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(31..3684)
                     /gene="rpoC"
                     /locus_tag="ACF3UO_001539"
     CDS             complement(31..3684)
                     /gene="rpoC"
                     /locus_tag="ACF3UO_001539"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFD3657572.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3763..7380)
                     /gene="rpoB"
                     /locus_tag="ACF3UO_001540"
     CDS             complement(3763..7380)
                     /gene="rpoB"
                     /locus_tag="ACF3UO_001540"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD3657573.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8108..9076
                     /locus_tag="ACF3UO_001541"
     CDS             8108..9076
                     /locus_tag="ACF3UO_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3657574.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9094..9999
                     /locus_tag="ACF3UO_001542"
     CDS             9094..9999
                     /locus_tag="ACF3UO_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657575.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            9996..10802
                     /locus_tag="ACF3UO_001543"
     CDS             9996..10802
                     /locus_tag="ACF3UO_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657576.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10959..11927
                     /locus_tag="ACF3UO_001544"
     CDS             10959..11927
                     /locus_tag="ACF3UO_001544"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFD3657577.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12244..12768)
                     /locus_tag="ACF3UO_001545"
     CDS             complement(12244..12768)
                     /locus_tag="ACF3UO_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFD3657578.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13055..14866
                     /gene="scm"
                     /locus_tag="ACF3UO_001546"
     CDS             13055..14866
                     /gene="scm"
                     /locus_tag="ACF3UO_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFD3657579.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(15021..16007)
                     /locus_tag="ACF3UO_001547"
     CDS             complement(15021..16007)
                     /locus_tag="ACF3UO_001547"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFD3657580.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(16030..16596)
                     /locus_tag="ACF3UO_001548"
     CDS             complement(16030..16596)
                     /locus_tag="ACF3UO_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFD3657581.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(16610..17026)
                     /locus_tag="ACF3UO_001549"
     CDS             complement(16610..17026)
                     /locus_tag="ACF3UO_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFD3657582.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(17483..19417)
                     /locus_tag="ACF3UO_001550"
     CDS             complement(17483..19417)
                     /locus_tag="ACF3UO_001550"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3657583.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            19719..20654
                     /gene="pplA"
                     /locus_tag="ACF3UO_001551"
     CDS             19719..20654
                     /gene="pplA"
                     /locus_tag="ACF3UO_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFD3657584.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            20744..21847
                     /locus_tag="ACF3UO_001552"
     CDS             20744..21847
                     /locus_tag="ACF3UO_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFD3657585.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            21860..22813
                     /gene="menA"
                     /locus_tag="ACF3UO_001553"
     CDS             21860..22813
                     /gene="menA"
                     /locus_tag="ACF3UO_001553"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFD3657586.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(23748..25094)
                     /gene="gor"
                     /locus_tag="ACF3UO_001554"
     CDS             complement(23748..25094)
                     /gene="gor"
                     /locus_tag="ACF3UO_001554"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFD3657587.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(25228..26481)
                     /locus_tag="ACF3UO_001555"
     CDS             complement(25228..26481)
                     /locus_tag="ACF3UO_001555"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFD3657588.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(26487..27410)
                     /locus_tag="ACF3UO_001556"
     CDS             complement(26487..27410)
                     /locus_tag="ACF3UO_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFD3657589.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(27631..30123)
                     /locus_tag="ACF3UO_001557"
     CDS             complement(27631..30123)
                     /locus_tag="ACF3UO_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFD3657590.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(30130..30597)
                     /locus_tag="ACF3UO_001558"
     CDS             complement(30130..30597)
                     /locus_tag="ACF3UO_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFD3657591.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(30733..30806)
                     /locus_tag="ACF3UO_001559"
     tRNA            complement(30733..30806)
                     /locus_tag="ACF3UO_001559"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30770..30772),aa:Arg,seq:acg)
     gene            complement(30864..30937)
                     /locus_tag="ACF3UO_001560"
     tRNA            complement(30864..30937)
                     /locus_tag="ACF3UO_001560"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30901..30903),aa:Pro,seq:tgg)
BASE COUNT         8982 a         6588 c         5780 g         9606 t
ORIGIN      
        1 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
       61 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
      121 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
      181 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
      241 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
      301 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
      361 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
      421 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
      481 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
      541 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
      601 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
      661 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
      721 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
      781 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
      841 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
      901 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
      961 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
     1021 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
     1081 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
     1141 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
     1201 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
     1261 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
     1321 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
     1381 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
     1441 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
     1501 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
     1561 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
     1621 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
     1681 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
     1741 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tcttttactt tgaatcgttt
     1801 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
     1861 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
     1921 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
     1981 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
     2041 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
     2101 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
     2161 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
     2221 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
     2281 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
     2341 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
     2401 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
     2461 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
     2521 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
     2581 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
     2641 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
     2701 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
     2761 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
     2821 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
     2881 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
     2941 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
     3001 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
     3061 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
     3121 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
     3181 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
     3241 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
     3301 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
     3361 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
     3421 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
     3481 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
     3541 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
     3601 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
     3661 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
     3721 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
     3781 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
     3841 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
     3901 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
     3961 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
     4021 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
     4081 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
     4141 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
     4201 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
     4261 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
     4321 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
     4381 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
     4441 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
     4501 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
     4561 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
     4621 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
     4681 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
     4741 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
     4801 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
     4861 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
     4921 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
     4981 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
     5041 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
     5101 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
     5161 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
     5221 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
     5281 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac catcatgttt
     5341 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
     5401 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
     5461 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
     5521 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
     5581 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
     5641 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
     5701 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
     5761 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
     5821 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
     5881 acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt ttgtgtgtca attcgccaag
     5941 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
     6001 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
     6061 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
     6121 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
     6181 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
     6241 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
     6301 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
     6361 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
     6421 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
     6481 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
     6541 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
     6601 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
     6661 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
     6721 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
     6781 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
     6841 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
     6901 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
     6961 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
     7021 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
     7081 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
     7141 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
     7201 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
     7261 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
     7321 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
     7381 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
     7441 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
     7501 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
     7561 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
     7621 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
     7681 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
     7741 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
     7801 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
     7861 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
     7921 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
     7981 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
     8041 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
     8101 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
     8161 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
     8221 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
     8281 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
     8341 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
     8401 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
     8461 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
     8521 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
     8581 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
     8641 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
     8701 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
     8761 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
     8821 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
     8881 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
     8941 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
     9001 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
     9061 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
     9121 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
     9181 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
     9241 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
     9301 gggagtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
     9361 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
     9421 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
     9481 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
     9541 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
     9601 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
     9661 atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa cggctttgct
     9721 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
     9781 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
     9841 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
     9901 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
     9961 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    10021 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    10081 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    10141 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    10201 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    10261 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    10321 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    10381 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    10441 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    10501 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    10561 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    10621 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    10681 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    10741 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    10801 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    10861 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    10921 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    10981 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    11041 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    11101 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    11161 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    11221 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    11281 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    11341 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    11401 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    11461 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    11521 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    11581 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    11641 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    11701 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    11761 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    11821 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    11881 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    11941 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    12001 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    12061 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    12121 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    12181 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    12241 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    12301 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    12361 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    12421 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    12481 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    12541 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    12601 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    12661 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    12721 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    12781 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    12841 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    12901 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    12961 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    13021 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    13081 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    13141 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    13201 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    13261 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    13321 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    13381 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    13441 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    13501 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    13561 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    13621 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    13681 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    13741 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    13801 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    13861 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    13921 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    13981 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    14041 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    14101 tgatagctca gattcatcaa cttcaagcga cagtacagat actacctcta ccacaagtga
    14161 tagcacggat acatcagctt caagcgacag tacagatact acctctacca caagtgatag
    14221 cacggacaca tcagcttcaa gtgacagtac agatactacc tctaccacaa gtgacagcac
    14281 ggacacgtca gcttcaagcg acagtacaga tactacctct accacaagtg atagcacgga
    14341 cacatcagct tcaagtgaca gtacagatac tacctctacc acaagtgata gcacggacac
    14401 gtcagcttca agcgacagta cggatacatc taccacaaca agtgatagca cggacacgtc
    14461 agcttcaagt gacagtacag atactacctc taccacaagt gatagctcag attcatctac
    14521 cactacaagt gatagcacgg acacgtcagc ttcaagtgac agtacagata catcctctac
    14581 cacaagtgat agctcagatt catcaacttc aagcgatagt acagacacgt cgtctaccac
    14641 aagcgataca cgtcatgcaa gtgtctcctt ctcaaaaaca agttcggata acaggacgaa
    14701 ctttaactta actaataaaa caagcaatga caatggaaac aaatcaaaaa gagcacttcc
    14761 taaaactgga agtcaatcga ataattggat aacactcgca ggcgttatat tacttgtaat
    14821 cggtttaaga atcactttta tgagttataa gaaatcgaaa aggtaaaaaa atattcaaga
    14881 taaaaaagag caacgtcgct aacggacgtt gctctttatt tttgcttttt atcataaata
    14941 caagaactac aattcaattt gtcaaaaaac acgtagattt ccttctgaga aatttattta
    15001 cgtatcgaac ctttccctat tcagtctttg cgatccaaaa tcagttgggt aagggaaaag
    15061 agattctctt ttgttcgaag agaggtggca ggtaatttct ttatttcctt caaagccttt
    15121 tctgtgtaag aggccgctaa cttcctagct tcttccacgc ctcctgtatg ttcaacgatt
    15181 ttgcgtacgg cgtcgacatc ttcttctgtc attgccgctt tcttctctaa ataaggtagt
    15241 agctttggtt tgtttttttg caaagagtag atcaacggta aagaatagac cccttgacgc
    15301 atgtcttcta gtacaggttt gccgatttcc tggctctctt ttgtataatc taaaatatca
    15361 tcgataatct gaaaggccat cccgatagaa agtccgatat ctcctgcttt ttttgcgaag
    15421 cgctcgcttg ttccactttc aaaagcgcca acagaacaac ttaattggaa cagttcagct
    15481 gtcttacctg aaatattttc caaatattct tttacagaaa gttcataatt atagcgatca
    15541 tccatctgac ctaattcgcc attcaatact ttttccatac tgcgagaatt caattggaga
    15601 cttttcaagg aagtggagta atcagacaat agtttaaaac agcagacaaa taaatagtct
    15661 cctgcataga cagaaacgac attaccaaac tgactacgga tattaggctg accacgtcgc
    15721 agatccgctt catcaacgat atcatcatgg atcagtgtgg ccgtatggag catttcgata
    15781 gaagctgcca aagcgatggc tttgtctcga tcttgctctg gtccaaattg tgagaacaat
    15841 agctgatagg caggacgcaa cagctttccg ccggcatgga tcgtttcttt gattgcttgt
    15901 tcgacaggtt tgtttttcag gcggacagtt tcttccatcc gttttagtgt ttctgtcaat
    15961 tctttactta aagcaggata gttttcccac attggatgta gcttcataaa aaaactcctt
    16021 gtgtgacgat tattttttgg taaacattgg gctccatttt tgtttggttc cctgctcata
    16081 atctttttgg aatcgttgaa gtgtctgcac atgtcgtaaa agataattcg ctgcgatccc
    16141 gattgcaatc cctgataaaa tccctaaaac tgaaaggact ggcaagtaca acatgactgt
    16201 ccatgattgt gcaatgaaag aagccatcaa aagctgtccg acattatgca tgaaaccgcc
    16261 ggccgcacta attccgatga tactgacacg ttttggtcct aattgcttga ccaataacat
    16321 tccaaaataa ctaagcaaag caccactcat actataaagg aatgtggaaa tcgttccgcc
    16381 tagcaaagta gtcaggaata gtcgtagcca aagtagtaag aagctgtctc gttttttcat
    16441 ggtaaaaatg gcaacgatcg tgattagatt ggctaagcct agttttgcac caggcgcaaa
    16501 agaaaaagga taagggatca tattttccaa taaaccaatg atcactcctt gtgcaacaag
    16561 tagcgaaata taaatcattt tttgtaattt actcatggtg tgtgaaggtc taataaatca
    16621 gactgtcttc gtcacctcca tctgttgaac ggacttcgat cactaattta tgtggcaaac
    16681 agacgatggt ttcgccattt ttcgttgccc agcctcgacg tacgcagatc tggtcatcgc
    16741 aatctgcttc ttttatccgt actcgatcgc catctatctc gatcaagtta taatctccgt
    16801 gttcatcttt gtaagtatat gtgttgctct cttctccagc catcaaaggg aatgttttga
    16861 tttctgtgcc atccacacgc agtaccgctt ctttttctgc tgttgcggtg ttttgctgaa
    16921 gaccaaaaat catgactggt aaaaaagaaa gaacagtcaa aagcaaaata ataaaaacat
    16981 cccaaggttt gagcagactt ttttcagcaa attctttaag gctcattttt gttctccttt
    17041 ttccagatta actcacccaa ttttagcata aaaacaagag gttgtgacac ctgtgtcttg
    17101 ctttgagtaa taagaacgaa gaatagaaaa cagctttcca tgttttctaa ttctttgggc
    17161 ttattaccga gaagcagcag gtggaacacc gtttataaca agaggttgtg acagaagtgg
    17221 gcaacttcaa gaaataagaa ggaatttacg aaaattactt ttcaagtttt tgtgaaattt
    17281 cggcttattt ttcgaagaag ctacttctgg aacaccgttt ataacaagag gttgtaacag
    17341 aggttgtgac acctgtgtct tgctcatgga ggcttatctc gggcatctta ttcctttaat
    17401 tttacataaa aaggaggctg tgacggtttg tctcagcccc tttctattga aatcttgcat
    17461 tcaaataacg ttctttatct atttatttct tgccgtactg ggaacttggt ctaccgtacc
    17521 accaattacc tagtgtacgt tgtagccatg gaattaccca gcgatccaac ccaatcgcac
    17581 gtccggaacc gttcatcaat gcgaaagcaa caaaaatgaa ccaaatgttt acccagtaaa
    17641 acatgcctga taagcagaac gtgatcacca atacaatcgt tgtcgcactg catagccatg
    17701 tgaataatcc agcaatcaat gctaatgcca aggcaatttc aaagaatacc atgaattttt
    17761 ggaagaacat tgctacatca ttgtttggca tgatcacttg catgatcttt gtgaaccagt
    17821 ctggtgactt ctcaatcaca gccattggtt cttcaccgta tgcataactc aaaccaaaat
    17881 gtgcagcttg agtcgctgct tctccggcac ttgcccctgc tccgctggca gctgtggttg
    17941 catcaccagc agcagaagca ccactggcaa catctgttac attgtattcc catgtccaag
    18001 ggaacacact gtttccagtg aaccatgatc cttcaccaaa ccaagtactt ggtttgaaca
    18061 cttcaccatt cccaatgatt tttttggaag cttcaacgaa ccaaactaaa ccatagaaaa
    18121 tacgaagtgg cacactccat aagacattgc cgtaacgaga agaatgtcct cgagtcacgt
    18181 tgcgatcatc tttgatatgg aaaaactcat gcattaaata ttggaacata taataaccag
    18241 aacgaatatc aaagaagtat ttcaaattca cgatatgttt cattacgata gctaaaaatc
    18301 cgcttaaatg gatcttatca aataggttag ctacccccca tttggcacca atagaaacca
    18361 taaatccttg atagtttcct ttaaatttat gcttttctcc gcctttgatc gaagccacga
    18421 tattcgctgc ggctgtgtgt cctgtttgtt cagcagcttg aacgatctgc ggtgtcggtg
    18481 ttcctgggaa ttcttcataa aagactaaat caccaatgat atagatgttt ttatcttcgt
    18541 agccttttgc ctgcatatat tcattggcga tcaaccgctg tccgcgtgct gattctaatc
    18601 caaagtcagc agcgtcagaa gttcctttga caccagctgt ccaaatcagt gtgtgagtcg
    18661 gaatgttgcg tccgtctttc aatttgatat gatcagcagc cacttctacg attggtgcat
    18721 tcaataataa ttccacgttg tgcttacgca aatagcgttc agcttttgca gcatcatttc
    18781 gatccaacat attcaagatc gtcggcattg cctctacgac catcagtgtg atttcgtttg
    18841 gatctaattt ataatctttg gctaggcgat ttttccagtc gatcagttcc ccaatcattt
    18901 caataccggt aaatccagaa ccacagacaa cgaaagtcag catggcttta cgcagttcat
    18961 catctggttc caatgcagct tttgctactg tcttctcaat atgttcccga atccttacag
    19021 aatcttcaaa tgaccaaagg gtgaatccgt gtgctttgac accaggtgta ccaaagtcat
    19081 tcggctctcc gcccattcca aggatcagct gatcaaaagg ataggaacct aatttggtct
    19141 tgacgatttt tcgttcttta tcgataccga ttacagtgtc tgtgacaagt tgtacattct
    19201 tttgacgagc aaacaaatgc tgcagatcgt attggattgc ttctggttct acacgtccgc
    19261 cagctacttc atgcaactcg gtcatcatag tatggtacga atgacgatcg atcagagtaa
    19321 ttgctacatc ttcttttttc agtttctttg ccaagtattt tgtagctgaa acaccggcat
    19381 atcctgctcc tacaacgaca atattttgct ttgccattga tcatccgctc cttatagact
    19441 atctatataa tgaatatatg ataattcttt tagtttgata cttattacac aatctccata
    19501 tattatatag atgttctgtt cttttgtcta actccttttg gatttttttc aaattttaaa
    19561 ataaagcgtt ttttcacgaa atttgctgaa agaaaacgtt tgaaatatta catgggttat
    19621 ttatcaaaaa tagttgactt ataggctaaa aagattagaa tgtataatga atcacaaaga
    19681 aaaattgtgg actagaaatg gaatggtggg gtattaaaat gaagaaaaaa cgttttgtaa
    19741 ctggatttgc cgtattagca ttttcagctc tagtgttagg cgcttgcggc gcagatgaca
    19801 acggaagctc aaactcttct tctgaatcat ctacagcaca atcttcgact gcaaaaagca
    19861 caacagaatc atctgcaaaa gttgtagctg gcggagattt gcaagacggc acatataaat
    19921 tagaagaaaa aaattattca aatggttacc gtgcagtctt tgaaatggtt gtaaaagacg
    19981 gcaaaatcac tgaatcaaaa tatgataacg tcaatgaaaa cggcgaatca aaaacaaaag
    20041 atgcagaata caacaaaaac atggaagcaa aatctggcac aaacccagaa aaatacattc
    20101 ctgagttgaa tgaccaattc ttaaaagcac aaagcgcaag cggtgtggaa gtcgtaactg
    20161 gagctactca ctcatctgaa agcttccaaa actacgcaca acaattgatc caagctgctc
    20221 aagctggtaa cacagataca atcgaaatcg acaatggtgc tgatttgaaa gacggcactt
    20281 acaagcttga agaaaagaac tactctaacg gctaccgtgt gcaattcgaa atgacagttg
    20341 ctggcggcaa agtaactgaa tcaaactttg attatatcga caaagacggt aaatcaaaac
    20401 aagatgatac agaatataat gaaaatatga aagcaaaaag cggtacagaa ccaaaaactt
    20461 acatccctac tctgaacgac gaattcgtca aagcaatggg cgaagaagat ggctcacctg
    20521 ctaatgtaga agttgttaca ggtgctacac acagctcaca ttcattcatc atgtacgcac
    20581 aacaattagt gaatgcagct gaaaaaggcg acactcaaac aatcgaagta gataatatcg
    20641 taacagaaaa ataatcacat aatcatacta ataaaagttg gagggtggga cgatagccag
    20701 attaggcagt cgtctcacct ttcaaaatga agagaggaaa aagatgcgga aaaaactact
    20761 attttcctta atcacactgg gcatctcttt tatggtgcta actggctgca gcaactcagc
    20821 aaataaaaca accactgaaa gttcagcagc taccaagata ttgaaagatc catattctga
    20881 tgaacagttc ttgttaggga cttacgttcg tatccgtgtg tatgatgaag gcaaagaatc
    20941 agcattgaaa cctgccttcg atcgagtaaa agaacttggt gataaaatca cgatcaatca
    21001 aaaaggttct gagatcgatg aagtgaatga gcaagctggg atcaaaccag taaaagtttc
    21061 tgatgacgtc tacacgttag tcaagcgggc ctacgaatat agccaagatt ctcaaggcgg
    21121 attcgatatg gcgattggtg caatcacaca attatggcga atcggttttg atgacgccag
    21181 aaaaccttcc caagaagaaa tcgatcaggc attgaaatta gtggattatc ataagatcga
    21241 actaaatgac aaagaaaaaa ctgtttatct aaaagaaaaa ggaatgatca tcgatttagg
    21301 tgcaatcgcc aaaggttaca ttacggacga agtagtgaaa gtcttgaaaa aacaaggagt
    21361 gaccactgcc atcgttgact tgggcggtaa tgtctatgtc ttaggccaca gcccaagagg
    21421 cgaaaaccaa gactggacag tcggcatcca agatccgaac atggctcgcg gatctgtttt
    21481 aggttctatt aaagaacgga acaaaacatt agttacctct ggaatttacg agcgttattt
    21541 agaagtagat ggcaaaaaat accatcattt gtttgatcca aaaacgggtt atccgttcga
    21601 caatgatatc gcaagtgtca cgatcataac agataaatca attgatggtg acgggttgtc
    21661 tacagcagtc ttttcaatgg gtgtgaaaaa aggactggaa tacgtcgaaa gcgaattgaa
    21721 taacgggacg gaagcgatct tcgtgacaaa agacgataaa gtatatgtga ccgatccaat
    21781 caaagacacc ttcaaattat cggaggactc ccattacacg atgggtgacc gttctgaact
    21841 aaaataagga gtacgaacca tgacactaaa aatcttttta gaagtagttg aaatacgaac
    21901 aaaggtggct agtgtatttc cttttgcggt aggggtatta ttctctatcg ctttttttca
    21961 tgagatacat tggctaaaca cttttttatt ttttattgga atgctagttt ttgatttagc
    22021 gactaccgct atcaataatt acatggatta tgaaaaggct cattctgaag tatataagta
    22081 tgaagaaaat gtcattggcc gcagaaatct atctcctgta ttgattcgaa acatgatttt
    22141 agctatgatt gcatttgttt ttgttatcgg cgttattcta acgatcaata cgggttggct
    22201 tttacttttg atgggattta tctgttgttt tattggagta ttctatacat tcggaccgat
    22261 tcctttatct cgaatgcctt taggggaaat tttcagtggg gtgactatgg gccttggaat
    22321 ttttgccatg gtcgtttatg tcaatacatt cggttcagat gtctatgatc tgacagtcaa
    22381 cttttcatct ggacaatttg ctttggtagg aaatctttgg gctatagcag caatcgtatt
    22441 agcttcctta cccttggtgt ttacgattgc caatatcatg ttggctaata atttgcggga
    22501 tcttgaccgt gatattgaaa atcatcgcta tacactagtt ttttatatcg gacgtcctgc
    22561 gggaacagtc ttattccagc tattgatgta tgcttgctat ttcgtgattt taatggggtt
    22621 gttgagcggt atctatgaat ggccgatctt ggtcaccttc ttgaccttgc caattgtgaa
    22681 gaagcatttg gatcaattca agcaaacgtt accccagcct atcagtttca gctattccat
    22741 caaaaatatg gtcttattca atgccagtta tgtattgggg ctattactaa caatcattat
    22801 gcaagccatt taacagcatg aagaggttgt gaaaaaactg ccctgcatca agtaataaga
    22861 acagccaaat aaaaatagct ccttatattt ttcgtttggt tgggcttatt accgcagatg
    22921 caagcttttg aacaccgttt atcaggaggt tgtgaaaaag tcgcttagtt tcgagtatta
    22981 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
    23041 aactggcttt tgaacaccgt ttatcagagg ttgtgaaaaa gtcgcttagt ttcgagtatt
    23101 aagaaaaatt ttgtgaaaat ggctttccac atttttgcat aaatttggct taataccgag
    23161 aaactggctt ttgaacaccg tttatcagag gttgtaaaat cagtgttttg tcctgagtat
    23221 tagagaaaca aatggaaaaa tagttcctca tattttgccg ttttttgagc taataccgaa
    23281 ggacagctga ttgaacacta tttgttcgga aaaagtgact aactatgaca caattttttt
    23341 cacagtccct tttttcactt gatttgattc gtaccagcga acttgacgag aactttcttg
    23401 gtttggtaac tatatggtat tcttttaaca tcctcgtttg cttcttctaa tttatttata
    23461 caaagtcaca cttttttaaa catctgttct tcgatacatt tctatttctt ttaaacatcg
    23521 ataccaatat tttgaactta agagtgcata ccaaatggat tcatttactc ttcgtcagtt
    23581 acgaagataa tcaaaatctc caacttccct acttatttcg ttttgagaat tatcgaagca
    23641 atcttacata aataactaaa aaacaaaaaa ccagaaaatc agtatactga ttttctggtt
    23701 ttacatggtt tgttcaataa aaagctgttg gaactgttaa tattaaatta tcgcatcgtt
    23761 acgaattctt ccgctcctgt tggatggatg gctactgtat tgtcaaagtc ttctttagtt
    23821 gcacccatct tgatagccac ggcaaaacct tgcagcatct catcgacacc aacaccaata
    23881 gcatgtaagc cgacgattct ttcttctttt ccgacacaga tcaatttcat ttcgcatttt
    23941 tggcgataat catttaatgc aaagtacatt ggggtaaagc gtgaacgata aactttcaat
    24001 tcattttcgc catatttttc caatgcttct tcttctgtca aaccaattgt tgcaattggt
    24061 ggatgcgtaa agacgactgt cggaacaagt ttatagtcaa gataagaatc tttctttcca
    24121 ttaaataaac gttctgataa acgtctacca gctgcgattg caacaggagt cagatctaat
    24181 ttaccgatca catcaccaac agcaaaaata tgttcatccg ttgtattttg gtatttatct
    24241 actttgataa accctttttt gtccaattcc acatttgtat tttccagacc taatttttcg
    24301 gtattcggta cacgtccacc ggcaaaaagt acacaatcac cagttaaggt ttcaccattt
    24361 tcaaatagca ccgtatattc gtcattgttt ttagtaattt ctttagcaat atgatgtgcg
    24421 taagttttta ttccagcttc ttggtacatt tggatcaaat tgtccgaaag cattttatca
    24481 aacgttctaa gtggtcgttc ttttcgatat gcccacatga cttcactacc taaaccacaa
    24541 aatacacctg aaagttcagc cgcaatgtat ccagcaccta aaacgattgc tctcttaggt
    24601 aactctgtta attcaaaaaa tccatttgaa tcaattgcgt attctccacc aggaatggtc
    24661 attttacttg cacggcctcc agtagcgatc aagattttag gagcacgata ggtttcaccg
    24721 tttacttcga tcgtttgact atcgataaaa gtagcgtaac cttttatagc ctcgacatga
    24781 ttgctatcta atcctctttg ataagcaccg tgtagaaaat caatatattt ttctcgtctt
    24841 tctactagac cggcgaaatc aacatttttt aaatctgctt ggataccgta acttgaggca
    24901 tctcgttcaa ttgtttccaa aatcgtactt gcttgccaca taactttttt aggtacacaa
    24961 ccgacgttga cacatgttcc gcccaattca ttcgcttcaa tcagcaaaac ttttgcgcca
    25021 tgcatccctg ctctgtttgc tgaagcaata ccgccagagc cgccaccaat tacgatgtaa
    25081 tcatatattt gcattttgtt cctccttatt gaagagatca atcaaaacct ttatttaacg
    25141 atcctttttc tacagaaaac aagtgtaaca cttttcttga attttgtatg cgaagatgct
    25201 taaaacaggg atatatcagc tttttcctta tttacgtttt cggatcatat ctccaggttt
    25261 caccggctgt gcgactggca tagttaaaat catcattgga tttggtgctc ggtcaatgga
    25321 ttcgccttct tcattatgca taacttcaac ggtttgactg aaatgactga atcctggacc
    25381 ataaaattcg atttcatctc ctacagaaaa caagtttctc tgacgtatcg tagcaatctg
    25441 tgttgcctca tcataagata atacttcacc gacaaattta tatactggga ttttacgacg
    25501 ttcaccgaat aattgttcgt tttcagttgg tgtattgtag taaaaacctg tagctaattc
    25561 tcgttgtgct actttccata actcgtcgat ccattcttgc ttgcagacat agttttcagg
    25621 atcttccata taactgtcta cagccgcttt atagacattt gacaccgtag atacataatg
    25681 gatcgatttc attcttcctt cgatcttgaa gctgtctacg ccgttttcaa tcaattctgg
    25741 aatatgttcg atcattgaca tatccactgc actcatcgag aattcttctt ccacttcgcc
    25801 tgtatcagtt aaactgtttc gttcttgacc aaaaggcata tcgaacaatc catacttcca
    25861 gcgacaagat tgagaacatc cgccacggtt tgcatcccgc atcgacatat ggttggacaa
    25921 tgtgcatcga ccagaataag agatacacat ggcaccatgg ataaatgctt cgatttcggt
    25981 atccgtattt ttacgaatct ctgccacttc ctccattgaa acttcacgag ctaaaacgac
    26041 acgttccaac ccttcttctt tccagaattc caatgtctca aaattagttg ctgaagcttg
    26101 agtggataaa tggatcggca gacctggggc ttctgtcgca caaatttcga tcaaagctgg
    26161 atcagaaaca atcactgcag aaataccgac atcacgcaaa ctgcggaaaa attcccctgc
    26221 tccatcttca tttccttcat gggtgaccat attagcagca acgtatacct tcgcatcatg
    26281 ttcttttgca aaagcaactc cttcagccat ttcttcataa gtaaaattac ctgcacggct
    26341 tcttaaacca tatgcattcc cgccaatata tactgcatct gctccataat ggatcgcggt
    26401 ttttaacttt tccagtgttc ctgctggcgc taggatttct ggtcgtttca attttctttt
    26461 tactgtcatt tctttcatca tactccttat ttgatagcag aaggatcaat ataaaagaat
    26521 cctgtatcta attcacggtt ttcaggatgc aatttactga tttcgctagt cattttttcc
    26581 gctttttctt gatcccagct accttctaaa atttgttttt ttgcttcggc gaatagtcga
    26641 gtgatgttta cgaatttttc gcctggagta aataatccgt ccaatttcca tgtacagtaa
    26701 tgatgctgat aaagttcatt caattcattc gagagattca gatcattgct ggcaaaaata
    26761 tgtgtgccat gactatcttc ataaatagaa taatgtgtct cttctttttt aggttccgag
    26821 ataaaaagac ctctttcacg atctttttgt tcgtcttgtt tcgtatagtt atagtaattc
    26881 tgtagcagtg gacgtttgga ttgatggatg catgtagcac catacacaag ggtttctaca
    26941 ggaatatcga gtttttcttc catcgccttc atctcttcaa aaggaacttc acgagcaagt
    27001 actgctccaa ctgcgccttt tttcgcccag aaattgattt gacgtgcgct cgttactaat
    27061 gtttcagcat cataaatata cggtatacgc aattcaggat tttttttcat cgtataaata
    27121 atacctgtat caccaactgt gatcacatct acgtttattt cttttaaaaa agccaaatat
    27181 tcaggtacat ttttcatttt ttcaggatga atgatcccat ttacagcaat attcgctttt
    27241 ttaccatact tgtgtgctaa ttctaccaat tgtcgctgtt cttctcgtgt aaatgaagca
    27301 ggcagacgca atccaaattg ctcttcaccg aaatatagtg tatctgcacc tgcagcaagc
    27361 aactgttctg cttgttcaat agtttctact gtggttatga gttcgatcat aattttctcc
    27421 tcctacaact tcataatagt agcatagctc taaaaacttt ccaatacttc ttctatttaa
    27481 agtcggattt ttgaaaatta tttcacaaaa aatcaaaata aagttcgata tattctgtcc
    27541 aaatataaaa agagattgtg acaaaaatct tgtcacaacc tcttaatcaa gtcttactat
    27601 tataaaaatt cagctacaca ggccaagtaa ctatagggaa cctactgttt cctttttagg
    27661 tccgcgaaca ttcaatgtga tcttaccttt tgaagcacct actgttacgt ggtcacctaa
    27721 acgaatttct ccgccaagca aagcctcgct caatcgatct tcaatttctt tttgaagtgc
    27781 gcgacggatt ggacgtgcac catattcagg atcaaatcca gctttcccga tcacatcgat
    27841 tgcagatggt gtgattttca cttgaatatc ttgttctttc aatcgtttga taatcgcttt
    27901 gctcatgatt tggacgattg tatggatttc atctttactc aatgaatgga agacgacagt
    27961 ctcatcgatt cgattcaaga attcaggtcg gaaagctttc tttaactctt ctaagatacg
    28021 tttttgcatg gctttgtgat ctttagtaac atcttggaca ttgaatccga catttttttc
    28081 ttctcgaatt tgtgtcgctc cgatatttga agtcataatc atgattgtat ttctaaagtc
    28141 cacttttcta cctttagaat ctgttaaatg accatcatcc aatacttgca gaagtaaatt
    28201 gaaaacgtct ggatgtgctt tctccacttc atctaagaga atcactgaat atggtttttg
    28261 acgaattttt tctgtcaact gtccaccttc atcataccct acgtatcctg gaggagaccc
    28321 gattaatcgg cttgtactgt atttttccat aaattctgac atatcaacac ggatcagggc
    28381 atcttcactt ccaaacatga cttctgaaag tgctttggcc aattctgttt ttccgacacc
    28441 agttggtcca aggaacatga atgaaccaat tggacgatca ggatctttca atccgcttcg
    28501 tgcacggcgg atcgcacgtg aaactgcttt gacagcctca tcttgaccaa cgacacgttc
    28561 atgcagaagt ccttccagtt ctaacaagcg ttcgctttct tttttctcca actgctgtag
    28621 agggacacca gtccactccg atacaactgt agcaacatct tcttctgtta cacgatcaga
    28681 ataaccttgc tcctgttttg cttcaattgc agaaactttt tgcagctttt tacgtagtgc
    28741 tttttcttgt ctgcgtaatt gagcagcatt ttcaaagtct tgtttttgga tcgctgcttc
    28801 cttttcttgt actagttcat cgatttctag tttgatcaca gttgattttg ttaagtgatc
    28861 ggtttgatcc aaacggactt tcgctgctga ttcatcgatc aaatcaattg ctttatcggg
    28921 tagttgacga gaagtgatat aacgaacaga aagattgact gctgctcgta cagcttcatc
    28981 tgtgatctcc actccatggt gctcttcata tcttgtacgt aatccttgaa gaatcacttc
    29041 tgcttcttca ggagttggct catctacttg aatgcgagca aaacgtcgct ctaatgcaga
    29101 atctttttcg atatattttt gatattcatc tagggtcgtt gctccgatcg tttgtaattc
    29161 tcctcgagct aacgccggtt tcaagatatt cgaagcatca attgctcctt ctgctccacc
    29221 tgcaccaatt aaggtatgca attcatcaat gaataagatt acttgaccat cattatagat
    29281 ttcgtcgatg acctttttca ttcgatcttc aaattcaccg cgatatttcg taccagcaac
    29341 caaagatccc atatcaagca tcatcaggcg cttttcttgc atgtcttctg gcacttcacc
    29401 taaaatgatt ttttgagcta acccttcagc aatggctgtt ttgcctacac caggttcacc
    29461 caccagtaca gggttattct ttgtccgtcg gctaagaatc tggataagcc gtttcacttc
    29521 tctcgaacga ccaacaactg ggtccagctt gttttctttt gctaatttcg tcaaatcacg
    29581 tgctaatgaa tctagcgtag gtgttccttg cggtgtttgc cgtttatctt gtacatttac
    29641 atttctacga cgattcattc cttttccagc agaatcacca gctagcccca ttttttgttt
    29701 cagaacttga cgggcttttg aaaggctgat acctaagttg atcatgattc gagtagccat
    29761 gatactttca tcttttaata agctcatcaa aatatgttct gttccaactt tttgagaacc
    29821 agttttcttc acttcgctgc tagctaaagc aaaaacttgt ttcattcttg gtgaatatgg
    29881 aagaaagact cctttagggt aagaacggat accaccataa ccaatcagat gttcaatttc
    29941 ttcataaatt tccgtttcat tcaaatccat ttcacgtaat acttttccag caattccatt
    30001 ttgctcgacc actaaggcta gtaaaacatg ttctgaacta actgattgat gtttcaaccg
    30061 ttttgcttct tcttgtgcaa tttctaatac tgcttgggct ctttcagtaa aaagttcttc
    30121 catctaatct cacttcccat cttcataact taaacgttcc agaaatgctc ggagaatccg
    30181 agcacgtgta tgatcttcat attcattgaa attcaatgtg ttttttgcaa ttgcactcaa
    30241 catcaagttt ccttcttttt ttgtaattat ttggtcttca taaagttttt gaataatagc
    30301 aaaagcattt ttctcactga ttgtatcatc aaataactga tttatctgct caagtaattg
    30361 ttttttatct gaaatcctta cttttgcaat tcgtatataa ccaccaccac cacgtttgct
    30421 ttctactaga taaccacgtt ggatggtaaa acgggtatta atcacatagt tgatttgtga
    30481 aggaacacag ttaaagaggt ctgccatttc aatccttcga atctcgatca tttcactatt
    30541 ttccagaatt ttctttatat atgattcaat taaatccgag gtattctgat gtgccatctt
    30601 attcattccc tttgactaat attgacctta attataacga atttgataat agaaagaaag
    30661 aagaacgctt tttgttaaat aaatccttta gaatcaacaa aaaaaaatac ggaatatact
    30721 attccgtatc gacgcgccca agaggagtcg aacccctaac cttttgatcc gtagtcaaac
    30781 actctatcca gttgagctat gggcgcatat tcaatttaaa aaaattataa atcatttgaa
    30841 aacaaaaagc aagataaaaa aaatcgggaa gacaggattc gaacctgcga ccccttggtc
    30901 ccaaaccaag tgctctacca agctgagcta cttcccgttt aaaaaataaa aaagac
//
LOCUS       DAXLPQ010000028        30414 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.028, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000028 DAXLPQ010000000
VERSION     DAXLPQ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.028"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..246)
                     /locus_tag="ACF3UO_001561"
     CDS             complement(<1..246)
                     /locus_tag="ACF3UO_001561"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3657592.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEE"
     gene            complement(248..2263)
                     /locus_tag="ACF3UO_001562"
     CDS             complement(248..2263)
                     /locus_tag="ACF3UO_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3657593.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(2442..2747)
                     /locus_tag="ACF3UO_001563"
     CDS             complement(2442..2747)
                     /locus_tag="ACF3UO_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFD3657594.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(2836..3867)
                     /locus_tag="ACF3UO_001564"
     CDS             complement(2836..3867)
                     /locus_tag="ACF3UO_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3657595.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            4074..4949
                     /locus_tag="ACF3UO_001565"
     CDS             4074..4949
                     /locus_tag="ACF3UO_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3657596.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(5101..5943)
                     /locus_tag="ACF3UO_001566"
     CDS             complement(5101..5943)
                     /locus_tag="ACF3UO_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3657597.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(6035..7912)
                     /locus_tag="ACF3UO_001567"
     CDS             complement(6035..7912)
                     /locus_tag="ACF3UO_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3657598.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(7909..9330)
                     /locus_tag="ACF3UO_001568"
     CDS             complement(7909..9330)
                     /locus_tag="ACF3UO_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3657599.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(9333..12722)
                     /locus_tag="ACF3UO_001569"
     CDS             complement(9333..12722)
                     /locus_tag="ACF3UO_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3657600.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            12979..14370
                     /locus_tag="ACF3UO_001570"
     CDS             12979..14370
                     /locus_tag="ACF3UO_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657601.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(14443..15090)
                     /locus_tag="ACF3UO_001571"
     CDS             complement(14443..15090)
                     /locus_tag="ACF3UO_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3657602.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(15098..15784)
                     /locus_tag="ACF3UO_001572"
     CDS             complement(15098..15784)
                     /locus_tag="ACF3UO_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657603.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(15790..16863)
                     /locus_tag="ACF3UO_001573"
     CDS             complement(15790..16863)
                     /locus_tag="ACF3UO_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657604.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            17085..17759
                     /locus_tag="ACF3UO_001574"
     CDS             17085..17759
                     /locus_tag="ACF3UO_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3657605.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            17764..19104
                     /locus_tag="ACF3UO_001575"
     CDS             17764..19104
                     /locus_tag="ACF3UO_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFD3657606.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(19253..20239)
                     /locus_tag="ACF3UO_001576"
     CDS             complement(19253..20239)
                     /locus_tag="ACF3UO_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFD3657607.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            20963..21994
                     /locus_tag="ACF3UO_001577"
     CDS             20963..21994
                     /locus_tag="ACF3UO_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3657608.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            22103..23635
                     /locus_tag="ACF3UO_001578"
     CDS             22103..23635
                     /locus_tag="ACF3UO_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFD3657609.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            23774..24586
                     /locus_tag="ACF3UO_001579"
     CDS             23774..24586
                     /locus_tag="ACF3UO_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFD3657610.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            24576..25061
                     /locus_tag="ACF3UO_001580"
     CDS             24576..25061
                     /locus_tag="ACF3UO_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3657611.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            25084..25629
                     /locus_tag="ACF3UO_001581"
     CDS             25084..25629
                     /locus_tag="ACF3UO_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFD3657612.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(25702..27345)
                     /locus_tag="ACF3UO_001582"
     CDS             complement(25702..27345)
                     /locus_tag="ACF3UO_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3657613.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(27474..29702)
                     /locus_tag="ACF3UO_001583"
     CDS             complement(27474..29702)
                     /locus_tag="ACF3UO_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3657614.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(29735..30214)
                     /locus_tag="ACF3UO_001584"
     CDS             complement(29735..30214)
                     /locus_tag="ACF3UO_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFD3657615.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT         8726 a         5775 c         5549 g        10364 t
ORIGIN      
        1 ttcttcgctg tcaatgatcg attgcaaagg tacgagcttt tcatcaggta tagaagttag
       61 cgtatctttc aaagaatgct caatgaagaa ataatcagcc atatcgctag atacacttcc
      121 aacatccgta tgacttactt caaactcgtc cacatctgct ccaagatctg caagtgcttg
      181 tttgatgttc atctctacca taaaacttgt tcctaatcca ctttgacata ctgcaaaaat
      241 tttcatatca ttcgtctcct tttcttatga tcgctaatat ttcttctttt gttgatgcgt
      301 gtaataaatc ttgaagattt tgtttattag aaagtagctt tgttaaattt gccaaagccc
      361 gaagatgtgc ctcattatcg atagcagcta aacagatgaa caaactaatg ggatgggctg
      421 gattatcaag cagatccaca ggttgttgaa gtttcagcaa agacatccct acttcgttta
      481 cgccatcttc tggacgagca tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac
      541 catactgctc cacgcgctcg atcatagctt tgatataact ttcttctatt ttattttctg
      601 ataatagcgg ctgtgcggca aatgtgattg cttcttgcca gttttttggt tgatccgata
      661 attggatcat ttcttctgtt aataattcag atagcatagg acgttgatcc tccttctttt
      721 ctaaaagttt gttcatttta cgatttaata cttgatagag cttttcttcg tctacgcctt
      781 cttttaattc gatataaggc agtagcgccg acaacaattc ttgggcagaa ggcattgaaa
      841 atcctggtat cagccaatct ctttgtactt gattgatcag ctgatttttt tccaagtcag
      901 tcatgattgg atgcagaaca tagagagact ttttcttatc agtaagtgtg agaggtacag
      961 tagaaaaaat aatatcgtaa gaagtttcgt caacctcgtg taagcggtca gctgaattag
     1021 tctctgtaaa aaagatcatc gggaataatt gctgaagttc actttttaag atcaatgaag
     1081 agctaatgcc acttggacag acgatcacgg ctcttatttt tctatttctt tcttctgcgt
     1141 ccgcttttct gatctctccg ccaaatagta tagtgaaaaa accaatctct tcttcaggga
     1201 tgctcttccc tattcgtctt tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg
     1261 aagcatattg atgcttaatt tgatcgatca tcacattagg taaataaaaa gaataggaaa
     1321 tacgaaaata ggcagggacc aagtgataaa agacattcat caataattca cgaaacgaag
     1381 caaattctac ggccatcagg aattccatgc gatggatgac ttctgaagaa cattccagca
     1441 aaaaatcaag tgcaggctcc tggacatctc cttcaacgat cgatgctaag caaagagaga
     1501 aaaatataat ctccgaattt tgatgttcgg aatagccaag gccagtcaat acttgtcgac
     1561 taatgtcagt gactgcaaga gaagccaaca gttcagcatc ttttaccagt tccatggatg
     1621 tttttccaat tcgaatggtt gtcaaactca aataataagc taattcatcc attcgatttg
     1681 gtgcgaatcg aagatctgat agtgaaatcg ttttatctag caaatctcta actttggcgt
     1741 aataatcaat ggaaagggtt gcggttaaat acgtgagccc aaatcttcca gcaagtgact
     1801 gcatcaaacg agcagtgcga ttttttgctt ctcttcttaa tattgcttct gaccctagca
     1861 gcctaaaacc agttttccta gtatacgaca gctgacaatc ttccacttct aattcatttc
     1921 ttatcttttt gatatctgac aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat
     1981 gaaaaacaga aacagacgtt gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct
     2041 cttgttcggt atacacagct tcaaatcgag taatatccaa aaatttttct gcccagtcga
     2101 ttgctcggaa tttctttata cggatacggg tatcatccac atattcggca aaaggagtta
     2161 attgtttgat cgcctcgctt gtatttactt cgatgatctc tgctgctttt tctagactga
     2221 tttctcttgg tgttttcagg agataactaa ttttgtagtt cacagcgctg ttcacctcct
     2281 acttatattc tagtatggta gcgcttttaa atcgaggggt gtttggtaca acttacagtt
     2341 ggattttttt tacgactgta ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg
     2401 tgaccaaatg tctcctgctt ttatgaattg atttcgtccg atcaatgatg atcatgttta
     2461 ttttttgagg tcagttcttc aaatttttct ttgacatctt caaccgcttt ttcgatatct
     2521 ttttcaaagt gattgggctc attaggcttt gtttcctctt ctacagaatt tgaaccagat
     2581 aaagctgttt ctttattttc tgtttcacca gagtttgtgc cagctaatga ttcttctttg
     2641 tcttctgttt caccagaatt agttcctgct aaagccactt cttcttctgt tttaggggcc
     2701 attgaacctc ttaatcgttt gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct
     2761 agtagttcta tactttttca tcgtacaata agacagttta tgcgtcaaaa aacaaacccg
     2821 attcttacaa atatgtcata tttttccttc tgattcttga atgcttttga ttccttcttc
     2881 caaaattttc atttgtaaga ttgtttcttc atctttgatg actttttctg cgccattaac
     2941 taatgtctcg taaatccctt cgtagacacg gctgtaatca ccaacctcgg aaattacttt
     3001 ttcttcatga taactccctt gttcatctat ataggtcaat acaccataat gttcgggcaa
     3061 atcgatacca aagtcttcat gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg
     3121 atcttttgtt tgtttcacga acatcccttt ttttccgtaa acgacgaaac ttggacgttc
     3181 tttgatgcgg aaataactgg attttatcga aattttcata tttccataga aaaaatccag
     3241 atcgaagtaa tcattcattc gtcctttccc taaaagttga cgtacatcat agctgatatc
     3301 atctggttcg ccgaaataag aaagaacttg atctactgta tgacaagcat gtccatataa
     3361 atagctgttc gcagtagaaa attcatgcgt attttctggt acttccggtc tgaaataatc
     3421 ataatgcatt tctacttcta aaatatcccc taattttccg ctttcgatta ctttttggac
     3481 tgtcaagaag tcagaatcga accgtctgtt ttggtaacat tggataaata gacctttttc
     3541 ttttgctaat gcaaataact cttctgcttc ctttgacgtt tctgcaaaag gtttctctac
     3601 tagtacattc ttaccatgtt cgagtgccat ttttccatat tcataatgaa attgactagg
     3661 tgtagtgatg acaactaatt ggatctcagg atcatcccaa agatcagaca gctgatcagt
     3721 atattcgatg tcttcgaatg ttttccacac tggttcagat ggggaaaaaa tttttttgat
     3781 attgattttg ttcgtaagtt ttcttgaaaa aggcaaatga tagcgatttg tactctttcc
     3841 attgccaaga taagcgattg taagcatgag tggtgcctcc ttttattgat gttttcagta
     3901 tatcctagaa aagcgcagaa agtatttata atagctattc tggtaaaaaa gttcagaaaa
     3961 acacttgtta tcattcggtt tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa
     4021 gatagtagcg gaaccaagtg tttatcagta agatagaatt tggaggtcag atcatgctta
     4081 ttgaagaaaa actaacaaaa caagagttgt ttaccacgac agagaaacgg attgtcgatt
     4141 acatccgtag gaatatcgaa gctgcagtct acatgacgat tgaagaatta gcaaaagcta
     4201 cgtatacttc ccattcagct atcattcgtt tatgcaaaaa aatgggattc agcggattta
     4261 aagaattccg tttcgagctg gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa
     4321 cgattgatcc taattttcct ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa
     4381 tggcggattt atcgatccag tcaataaaaa aagcacaatt gcagattgaa catgaagatt
     4441 tagatcaaat cggtaaagta ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg
     4501 attctcaaat cacggcaagg aaattccaga ataaaatggt caagttgaat aagtttttga
     4561 tcatggctga agaatacagt gattcttctt ggaatgcagc caatttgact agcgaggatt
     4621 gcgccatttt tattagctac agcggtcgca tccatcatta tgaacgaata atgacctatt
     4681 tgaagcatgt agaggcccct accttgctga ttaccggaaa tcagcattca gaaatggcca
     4741 aacaggctga tatgtgtctt gttatatcgc aggaggaata tgattttgct aaagtagcga
     4801 ctttctcctc tcaaattgcc ttcgattacg tattaaatac gttattctca gtgatatatt
     4861 ctcaaaattt tgaagagaat atccgcaact tgaaaaacaa acaagaattg atgcaaaaag
     4921 gccttcttaa agaatatcgg aaaacttaag aaaagatcct catttagtaa taagaaagat
     4981 agtgtttgat aggctctctt tgatatcatc ataaaaacag gctgaagttt tctttttcaa
     5041 acctcagcct gtttgtttac ggaacgattc gaatagatat attatagaaa tgaggaatag
     5101 ctaacttctg tttcttattt tgaacgattg acgaaaaaga tatataagaa ggaggaaaat
     5161 cagtatacat gcagctaaca atccatacag gaaaaatcgt ttgttctcgg atactttctg
     5221 tacttctttt tgaacttctt ttgcatgata aggaacccgg tgccctctga caagtaagcg
     5281 atgactgttg accatataag gtgtacaagt taggagtgtc acgaaatcct gccctttttc
     5341 gattctcaga tcttttgtat cagtcggttc taccgtcttg atctgatcga cttgataagc
     5401 gagtgtccgt ccattgattt cgatatagaa agaatcacct aaagtcagtt tcggtaagtc
     5461 tgtgaacaac tttgcttgag gcagtcctcg atggctggaa ataacggcat gtgtattttc
     5521 tccccccgta ggataagacg ttccttccaa taatgaggca cctttttcta gcagcacagt
     5581 attcgtttca tcaaaaattg gcaaatggac attgatctca gggatcgtca aaataccgat
     5641 cgtatgtttc tcaaaatagg ttctatcctt tttcgcaggt tcttttttct tagtaaaggg
     5701 atctgcacct ggatttccac cttcttttgc taattgctgg tttttctttg tcatgttttc
     5761 ttggatttta gccatgactt cttcattttc tttgaccgct tgttgctgat aatgagagat
     5821 gatctgctga tccagataat tattcagcgc gtcgctaaca aatggataag ctagtatccc
     5881 tattcctgag agaagcaaga aaagcatcag cagatctaga agtttccttt tctttggttt
     5941 catttgtgtt ctccttgtga tgactgtttg ataataaaag aaaaaggagc atttgcgtaa
     6001 tccgctgctc ctttttccaa ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag
     6061 caaagtacag tccagcaatc agtagaagga ctactcctgc accgatatac acatagattc
     6121 ccttaccgcc tgttgaagga agtgtacctt tgtgtttatt tggtattttt tcaggagaaa
     6181 tcaactgtcc tgctgttaca taagattgtt catcgatagt aaatgctaca cggtttgtta
     6241 atggaacata tttttctggc gctttcgttt cttccagata gtacgtgcca tattttagac
     6301 ctgtcacatc gattaaaccg ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg
     6361 atacccagct gacggctttt gtggatgggt cgatcgataa atatttcgct gtgtcactat
     6421 cttgatcacg aacgacgaat tctgctccag caagtgtttg gtctgatgta acgtcaccat
     6481 ctactttaac aaatcgtttg cccccagtaa cgacatcgac tgacggtggt gtttgatcat
     6541 ttgtatgccc gttatcgaca tttgcttggt tagaaaatcc tttggttgga tctgcttttt
     6601 cgttcaaatg catatagtaa acgaatttca atgtaccgcc aggagttaat gaaggaatat
     6661 aattcggatc aactgaaacc gtgaatccgt ctgtttgctc agtgacagaa taatttactg
     6721 ggtcgatttc tttatttcca tcatataagg cataagcata cgttcctgaa gaatcattat
     6781 caaatgttaa agcagcgtca tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg
     6841 ttccttcttt atcagcgata cctaatggga tattgacaga aatctcatat tgaatttttt
     6901 caccgattgc gacatctttt ccattcaatt gaggtgttgt tttatcaact ttagacgtat
     6961 catttttgat ggtcttttct actggtgttt ggctatttgc caggatctca aaaggcgtga
     7021 ttgtttgctt ttcaatcatt tccgcattat caggagcttt tacttcttct aaattatatt
     7081 ttccaacttc taaatgatta acgatcaact ggcctttttc aatagatgcc tcggcaaagt
     7141 cattgttgcc gatgtcataa gaatgaccag taatgaaatg tttggctttg gtttgatcag
     7201 ttgtccaagt gtacaatcca tctgtgacac tttggatgta ttttttgacg cttggtgttc
     7261 cttcttcttt agaaataata aattctgctc catttagtgc ttcgttttcg gcagtaccga
     7321 tttttgtaac tttcaacgtt ccatcattac cgactgtatt tttagggtag agatggatag
     7381 tatctagttc ttctgtcccg tatttataag agccatctgc ttgtttgatc atctcatata
     7441 cagggaaagc taaaaccatg tttgcggcag ctgacactcc gtcttttggt tcttctttga
     7501 tcgtgtagac tgcatctttc ccattttgtt ttttaggtaa agataaagtg acatttccat
     7561 cagcatctgt cgttcctgaa gcaactggtg taccaggagt caaagactgg actgcttgtt
     7621 ttgctgcatc cacggacgct cctttatctc gttgcgcata aaattcttga gtgacgttat
     7681 aaactgaaaa tgaaatatcg gctaatcctt ggtattgatc gaattcgctc atttctttcc
     7741 cgctgttttg gattaaagga tcgggtaaat cagtcatttt ctttttatga aggatgactt
     7801 gagctgctgt ctcctctgca aacacttttt ttgcgccgaa gctgtttgtg agtaatggta
     7861 aaataaggaa aaggactcct aacataacgt ttattttttt atgatttttc attttttcac
     7921 tcctgttctt tttttgataa acaaccagat tgcaaagctt gcgaatacca taccaacaac
     7981 gcctaaaagt gtatttttcg tttcgtttgt ttttggaaga aatggacggc tattttcttt
     8041 tttattgact actttcaata tactgtccgc ctctttatcc tcagaaagaa aagttgaaat
     8101 ggtaaacgga atttctgttt cacttaaaat ataaccagaa ggtgcttcga tctcttttaa
     8161 tcgataactt cctgttttca acccggaaat tgaaaaagcg ccatttttat cggaaatcag
     8221 gtgaagcgca tctgattcgt tctttgtcca cttgtatccg ttggctgttt gctggaggta
     8281 atttcctgct ttgtttttaa taaggaatac tgcgccagct aatcgtttat ctggtttatt
     8341 tgtctcgatt ttgacaaatt gcttactccc tgtatataca gagactttct ttgtactgac
     8401 accaaaacca aaatccagtg ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact
     8461 gcttagctgc atctgataag aaatggtcag tttttttcca gcatattttt ccaacgaagg
     8521 gatcgaaaat aaaacatcaa atccgtgagg tttcttgtgt atgacaaagc cttctgtcag
     8581 cttttctcca ttcgatgaaa tcgttaaact attaggtaaa aacgttaatg cttcatccgc
     8641 actatctgac aattcgaact tttgatagtc aaggatattt acaggaattg tcgtatgcaa
     8701 ggaataagtg attttttcac caatcgtaaa atcatttcta ggctcttcta ataccttctc
     8761 aaaaggtgga tcagggtagt cgttttcttc atttttagga tacaaatgga tagttgaaag
     8821 tttttgattg ttttgtccat gtacaggaag aacaactacc atattctctg ccttttcttt
     8881 gacgacttct ggtactttgg attcaatgaa aagatacgct ttatctcttt tttcttgatc
     8941 tttagcggcc agagaaaaag aagcgatacc atcttcgttg ttaagagttg tagttgttgc
     9001 ttctgcggta aacataccgg aagacgcacc gttttttgcg atctctgctt gtgcttcttc
     9061 taccgttttg cccttttccc gtagatggta aaaagaatct gtgacatcat aaacttggaa
     9121 tgtgacacca tttaatcctc gatacgtttg taataaagct ttttcttgtc cgtcatttgg
     9181 atgatttttc ggcagttgcc cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat
     9241 ttctgtttct gtttctgttg ctacctgagt aaaagctggt ttaaatagta acaagaagag
     9301 acacatacta agccaaccaa gttttttcat atttagctgc cccctctttc ttttttcaaa
     9361 aaaagatacc aaatagaaaa cgcacaacca atcatcccta ctagatagat tcctaaacgg
     9421 ccaattcctc ccgtttcagg taatggtact tttgcctgat tcgtgatgtc taaagaaatc
     9481 tggttgtttt tggctcctgg tgacagaaca gattcatgat cttgtccatc cacttgaatt
     9541 gacccatctt cgtgtataac tatagtaact ggctctttta gaccttggta tccttctggt
     9601 gtaaaagttt cggtcagcgt ataagttcca ggttttaaat tttcgaatag aaaggtatct
     9661 gtttcttgtc catcttttgg cgattctaag tccatttctg gtccctgcag tctgaatttt
     9721 gctcctttta atgtctgtcc gttgtcttct tttttgtgta ccgttagatc aaacgctttt
     9781 agtcgatttt gatgagtgag cgtccataca ttatttgtca tctcggtatt ttttcccgtg
     9841 taaatgattt ttccatattt atcgatttgg aattcataat ttcccggcga agtatcatat
     9901 ccggcaggac cagctgtttc aacgactcga tatttaccag gtgtgagtga atcaaaactg
     9961 gcaagacctt tttcattcgt tgtttggctg tcaattggct gataagtacc atttgcttct
    10021 tttttctgta gggaaaatgc tgctccttta agatttatct ctttgtccgt cccttgcatc
    10081 gcatacttac gtactgctac aggaacttca acaaaaggat tttcaatagt caactggatc
    10141 gtatcatcgg aagtagtgac tgtttttcca tcaatggtta ccgtaccatc agaagcgatc
    10201 ttgatttccc aagtagtctt tttgcttaat ccatgccctt ctggagcttt tgtttctgtc
    10261 agcgtatagg tcatttcttt ttgcaatttg acattttctg gaagagaata ggttccgtcg
    10321 ccatgatctg ttagtaaagt atcaatagaa tctcctgtta atttgaaaac agcgccaata
    10381 agatcctttt cacctgtaga ggaatttttc gttattttca agtttaacgg tgtgaattgt
    10441 ttagtatttt tccatgtcat tgcatctatt tgttgagaat cgtatcctgg tacaggtaat
    10501 tctttgattg tttggtaact gaatgcttga ccttgattat tgtattgagg tagtgataat
    10561 atctcttgat aactttctcc gctatttgca gataatttgt caatgtctgc acgttcccac
    10621 gtatttgttg tatctttagc tggtttaatg attcgaatat atccgttttt ccaagctgca
    10681 gcatttgtcg tatgttcccg ttgaatctca aaagtaactt gatctggacg atcagctaga
    10741 ttgttgtcaa attcttccca taactttttg atgtgaagac tgactccggg agctttagca
    10801 gatggtatac cgaattcagc taattcattg gtatcaatgt ttggctggaa agttgtcctg
    10861 ccgttcattt gataccagaa atttggatgg aagtcctcat tttctgtttg gattctcact
    10921 tggtaatgga tttggatttc ttggtctttt cctaaataga tctgattgct cttgatggta
    10981 tttccttcta tggaaataga tggagtgacc gttgtaggac ttgtccccac actcttgact
    11041 gaaagtgtac caggctgata aatgaatggt tctgcgattg gatcatttat ttgtccattg
    11101 cttacagttg ctgagatctg tacagctttt ttggctaggt attcagagat atctgttgca
    11161 tgatcagctg attcatagta aagatcgcct ttttcatctg atgaaaccat ttgtcgcata
    11221 cgagactcta cttctgcttt tgagagacca gctgccggat cgctttgaag ttggatgcca
    11281 agaccatgta tttcgattcc tcgttctttg agtgccatcg cttctccgat ggttgcgata
    11341 aacgtactgt cgattcttct ggatagattg ttttggtcag gtgcatcata gattcttgag
    11401 attagagaag tatttcccgg ccgatcttgc gtattagaaa actgagttcc gtaataattg
    11461 ctgcttgatt gtgcgtgtac ccgctgtact ttataggaaa atgttggtac accatccgtc
    11521 agcaaaacga tcactttttt atgtccattt ggaacggata gcatgcttcc tgcatctctt
    11581 agtgcttttt gtgtaaaagt accaccattt gtccgtgaag gtgtaatgga ttttacttga
    11641 tttttcactg aatcaaatga acccatctgt actgcaccgt tactgtagct atatccttcg
    11701 cttgagtagc cgacatatcc catattgatt ttgtctgtga taccgctatc tgctaaagta
    11761 tcgacaaaac gatcgacacc aatctttact tcaccgatcc gattattgtc gttcatactt
    11821 cctgaccagt ctacgaccaa tacgagatca agaggcgtga tatctttttg tacatttcca
    11881 cgagcattca aataaacatc aaacaatccg ggtgtacttg tttcctttgc atactttcgt
    11941 atcgcatagt ctgcttgatt accggttcct ccatattcga tatacgaatg ggtccgatca
    12001 ttaggatctc cattccaaga atttatacca tcccattgat ttgttccgtt tttattgcct
    12061 tgatgatcaa gaacatttgt atttcctgta ggttgccaac tggctttagg ataagtgccc
    12121 tgatcatctg ttgtatattc tgtaggaatc gtttgattag atggcacact cacagctggc
    12181 aaggataatg taggcaatgt aaatgggctg acagaatttt cgttttcttt tgatgattct
    12241 tcttctattt cgtctggctt tggtactgac acatctgtat ctttcttatt ttctgtctca
    12301 tcaataatgt catattcttt attatcgacg atcagcttgt ttgcctggct gtggtaaagt
    12361 gctggatcga ttggaaaact cagatcgata gtttgtttag tgtttgatga gatttccaac
    12421 gtaattttcc cgctatttac ctgataagca tagccatctc cttcttttct ttccacatca
    12481 cttaagtaat tttcgactag accaatttct ttttctatct tttcagcact ggtgttattc
    12541 gcatttagct tgatgttcag tgcttttttt ccagactgat ccgaaatgac ttcagctgaa
    12601 attgtttcta aaactgttgg atcatctgta gtgtctgcta ttgcagataa tggcacaaag
    12661 tttgataaac tcaatattat cagcatgaaa ataactttca gtttcttccc tgtggtcgtc
    12721 atttttcccc tcctttttct ttttttctgt tttgacgtga atagtgaaaa ttattaaaat
    12781 aaacaggcgt tacataattt tatttatttt aatatgataa ttattatacg aagggcgcta
    12841 aagggaatca caccaatttt cataccaatt ggtttcattt atgaagttga ttccttcgat
    12901 taatgagcgt ttcattgaaa gaaaagggtt gagggagaaa aacatatgat caggttgttg
    12961 gaattaaact atagaaagat ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg
    13021 atgactaaaa aagaacttgc caaacgaatt ggtagttcag aatctacatt tgtaaggtat
    13081 atcgaagaga tcaaaatccg ctggggaacg gatgtaacga ttcaatcttc acaaaaattg
    13141 gggtatcgtc ttgaacattt gaatgtacca gcttatttaa atgttctgat ggaaatgtcg
    13201 caaagttcta caaacagtcg tttattaaat gagattattg tcaatccggg taaaacgatt
    13261 gagtattatt gtgaaaaaat ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa
    13321 tgcaatcaaa ttttagaaag ctatttatta aaagtgatcg ttgaccaagg ttttcagtta
    13381 actagcctta aaagtgagct ccagttgcgt atctttgtta cctttttctt tttaagttac
    13441 tacggaagac gcacgttgcc atttccaatc gaaaaaaaga agatcaaaga aattatggtc
    13501 aagaataatt gtcagatgaa tttgtttcag gaagaaagcc catatgagca atctttcttt
    13561 attatgtatt ttgttgtgca tctcatgaga gaatcccaag gaactccatt tgaatggaaa
    13621 gctggagact cttatgtaca gttgataaat atcgataaaa aagacttctt aatcttgaaa
    13681 aatctcttag gaaaattgaa gtacagcagc tatataaaag tagtgaacta ttttgtcaat
    13741 acgatttttt cagaattttc ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa
    13801 aatatgtcct actgttcgtt ttcatccgct gattgcaaag aaaaaaacga agaatatgtt
    13861 gttcaattat taacgcaaat ttattttttc tcccgtattt tcccatacga tacgactcat
    13921 ttgacgatcc gtgcaactta ctttgcacag cagatgcaac accgccagat acgtctatat
    13981 gctggatttc gtgcagaact tcaattttat tccactctac tgaatcagaa tctgatttat
    14041 tatttatcta gctatatctt ttggatgctt atcggtaatc ctgaaattca ccattatact
    14101 tctgataaaa aaatactgat tatcagcgac ttaagtcttc gacatagtca atatattgaa
    14161 gaatatatca gtgatattct tgctgtgcat aaaattcact ctgagacaac tgctattact
    14221 gaagatcagc tgtcgaaata caatcttctc gagtatgatc tgatcgttac gaatcaaccc
    14281 attttgaatg cccatgttcc tcatatattg attgatgata gtgtgtcatt cgcaaatgaa
    14341 gaagaactca tccgcttatt cgagttatga ataatcaaaa aacagctatg tataaaccac
    14401 cctgataaaa atttcaggac aaatacacat agctgtttct ttttattgta ttccttcagc
    14461 aatccaacga gatttatagc gaaagtcttt taacaactct tcttttgtcc aattatttgc
    14521 aatgagatcc gtcaaagtgt tcattacgag ggtcatggaa aagtatagga aactaactgc
    14581 ttcttccgac gattgaatgg agaaatgatt gattcttaat aattccagcc atttttcgtt
    14641 cattggagaa tcagccgata gttctctacg tttggttgtc tgctgatcat ttcgctgggt
    14701 taacaagtat aacctttgcc aatagatact ttcgtgatct aagtcgcagc accactctaa
    14761 atatttttcg atccccaaaa agaaatgttg tttgttttcg ctaatgaatt ttaagatatc
    14821 ttgatggact atgtgagaac tgcttttgat cgtatacaaa taagcatctt ccaaatcttg
    14881 aaaatattta taaaaagcac cgcgcgacat ccccatcttg tcaacgattt ctgagacttt
    14941 gacttggctg atgtgctgtg agcaaaatat ctccagtaat aggtcatcga ttctctgttt
    15001 ctttgcgttc gataaattga aaaaagtttc ttttggcatc cacatctctc ctttatctct
    15061 gattatacgt ggatagccct tcattgtcat gaaggattca ttccttcttt ttctcttctt
    15121 ctgtcaagta cccatcttcc attcgataaa cgcgatcact ccattgaatc atacggacat
    15181 catgagtaac cataatagtc gctttttgtt tctcatgagc ttctttaact agtaatttga
    15241 cgacttcata tgcatgatct gtatccaaac tagctgttgg ttcgtctgct aagatcaagc
    15301 ttggctcatt atataaagcg cgagcaattg ccactctctg tctttctcca ccagaaaggt
    15361 ctttaggata actattttta agtgactgga tatctaaaga ttgcagcaag gaatcgattt
    15421 ttgttgaatc ttcttttttt gaagtaactt ggtcaactag ttcaaattgt tcctttaccg
    15481 ttaaaaaagg aatcaaatta gagctttgga gaataaatcc tatttcttta aagcgtaaat
    15541 ctgctcgttt tttttctgga agctcagtta gtgagtgacc gttgatcact atttctccgg
    15601 aagtcggtgt ttgcaatcct cctgaaatgg taaggaaagt acttttacct gaaccagaag
    15661 gaccaatgat gctgacgaat tctccttcct ttacataaaa atcaattgct ttcaaagctg
    15721 agacctttgt atgaccagaa ccaaatgttt tggtaacttt tttcatcgtt aatatttttt
    15781 tcatttttat taacctccta ttgctgtaat tgggtctact ttggttatcg tacgtatcga
    15841 aaacaatccg cctagcattg cgacaatgat caaaatccca ctatatagca accattgtga
    15901 ccaaaaaaca gcaaaaggca tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa
    15961 aagagcaagc agaacgccta ccaccccaac aataaaggac tgtgctacta aagatttagc
    16021 gatgaagaaa tttttgatcc cttgtgcttt cattactcca aaaatagcag tcttctgaag
    16081 tgtcatcacg tacatgaaaa taccgaccac ggcagcaacc actaagaaca aaaagtatat
    16141 catcgcattt aaggtcatat tttgggcaga atagccagga atactttcaa tgaatgtccc
    16201 aatagttaat aactgtagac ccttcgatgc tttttctttc gaaattttag ctgaatcctt
    16261 tattacgatc ccattgatcg gctgttcttc ttcagaagca aacggctgtt gtccatactt
    16321 caaagcagtc cacgtatcta gggacgcata gatgacggga gaaactgtgt aataagtttc
    16381 aggaaagata ccgacaatcg tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc
    16441 aattttatag cctgaatcag ccagattttg agagatgatg atttcattct ttgttttaaa
    16501 ttcatgccct ttcgtgagtt ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt
    16561 aacattttct ttgttttttc ctttgattgc tccgctgtac aatccgattg gtgctttctc
    16621 tcctccttca atgtatttca gatctcctct tgttaattgt gaagctgcaa atacttgatt
    16681 tgcatcctcc gacaaaacaa tctcttgtgc gtcccaatca tcgattgctt ttttaaactc
    16741 ttctgaaagt ccattcgcta gtcctgacaa catgaatacg acatacgcaa tcaagaacat
    16801 aataccgacg atcaagccat atcgtaattt agaatagcga atttctttga tagctagaaa
    16861 catttgtttt tcctccctat gatagattga tagtgacaaa atgtcacttg ttgaatagtg
    16921 taactctaaa gtgacaattt gtcacttgtg ttgttttttt cttatcaata aattgtctaa
    16981 gacatctttc gataaaacct taacatgagt cataaaaaat ttatttaagc cttatttatg
    17041 ctttccatga taaactaaag tgaccaaatc aatgaggtgg gaaaatgatt aaactattag
    17101 tagtagaaga cgataaagta ttatccaata atataaaaga aatactcgct gcaatcggcg
    17161 agataacaca agtttatgat ggtagtgaag gactgttcga gttggaaagt ggagtttatg
    17221 atcttgcaat cttggatttg atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa
    17281 tacggaaaga aaaaatacag actccagtat tgattttgac tgcaaaagat agtttggaag
    17341 ataagattga aggatttgaa cgaggtgcag atgattatct aacaaaacct ttctatcgag
    17401 aagaactgat catgcgcgtg aaagcattat tgaaacgctc gctaggtctc tttgatgaaa
    17461 atgttctgaa gtataaggat atcagttgtg atttaaaaag caatgaagtc ttgtataaag
    17521 aacaagtttt gcccatacaa ggaaaagagt ttgaattgct cgtttatttt ttacaaaata
    17581 agggaatcat tttgacaaaa gagcagatat ttgaccggat ctggggattt gattctgata
    17641 cgacgattac agttattgaa gtttatatga gcaacttacg aaaacatctg cgaagtactg
    17701 gattggataa agaaatcaaa accttacgta atgtcggtta tatactgcaa agggtgtgat
    17761 gcaatgaatg gagatattac acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca
    17821 gcatttgctt ttatcttttt tcttttggga ttcattactt tacagatatt aaaccaatct
    17881 gcatacagag aaacagatct gtcattagag aaaataaatt ttgattctcg aacagtacaa
    17941 ttagagatac aaagatatca gcaaggcgat ccctttttaa acccgactca aacggaacaa
    18001 aacagaacaa acatggaaca gccattaatg gaaccatcaa atgaccgttt taacactcaa
    18061 gtgatcttgt ggtctaaaaa tggtgagata ttgaataaag cagctattgg tgggcgtttc
    18121 aaccaaatca aagaattaaa aatggatacg aaaaatctga ataccatcca aaatattgaa
    18181 ttaaatgaag acagtggctc atctgccctc tctttccgtt cgattacgaa aaaagcggag
    18241 acgaatcaag atggcgttgc ctacatccaa attttagaaa atacaaatca aatcaagaat
    18301 tcattagcga cttttcgcac gattatgatt ttgtgtatga ttgttttttg gattctctct
    18361 attggtatca gttattactt gtctagtcta agcatgcgcc ctattattct ttcttggaga
    18421 agacaaaaag aatttgttga gaatgcttct catgaattgc gcacaccgtt aacgattatt
    18481 caaaatagtt tggaacatct ttttaccaag cctaatcata ctattattga agaatccgaa
    18541 agcatcgctc aagcattgtc agagacgagg cgcctcactg gattgacttc ggatttgctg
    18601 acaatcgctc ggaatgattc tgatcagcag ctgctttcaa agcaaatgat caatacacaa
    18661 gaatatatcg aacaacttgt taaaccattt caagagatgg ccatcataga tggaaaagag
    18721 tttattctcc ataacgatgc aacattagaa gtaccaattg atgaaaaaaa aatccatcaa
    18781 gttttggtta ttttgctgga taatgcatta aaatatacga atccagaaga taagatcatt
    18841 ttggattcat ctgttaacca taaagaatgg ctgattcacg taaagaatac tggcccttct
    18901 atcagtgaag aagatcaagc aaggattttt gatcgatttt atcgggaaga tcaatctcgg
    18961 gcgaaagaga ctggcggata cgggcttggc ttggcaattg caaaacaggt aatcgaacag
    19021 catcatggac agatttctgt atccaattat cttccacaag gagtcgattt taaagtccaa
    19081 ttgccgttga agcctaaaaa ataatgctta tccctaaaaa agggctgtga caaaaatctt
    19141 gtcacagccc ttttttgttg cgaataaacg gtgttccaga agtagcttct tcggaaataa
    19201 gccgaaattt ctttaagctg accacttctg tcacaacctc tttagcttac gcttacgatt
    19261 ttttattgcg gtcttcaatg tgtacatcac cgcttgtgtc aatatccaat tcttctcggc
    19321 taacatcttc tgtcactttt tcaacatctt catgttcttc tttatgaatc ccaacttctt
    19381 cacgaataac tgtatgtttg cttacatcta cttgctcttc tttgattggg atagtaatcg
    19441 tgtcatcttc caatttttcg tctgttccct gtgaagattg atctgttact ggtttgcgtt
    19501 cgatgacgat ttcttcacgt ttgaccggta cttctaccgt ttcagtatcg ttgaccacat
    19561 gtttgtggat gtcgacttct ccagttgtca catcatgtgt atttacatct aatttttctt
    19621 cttttagttg aattgtatca tcatctagat ttggtttgcg atcgatgtct tcagtcttgc
    19681 ttgtacccat tgtatcagtc tcgccaggta cgtccatcgg atcagttcct ggtgtcatat
    19741 tcaatggatc cgttgtattt tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc
    19801 cagtgccagt ttctaatcca gtccccattg tgcttgctgg gctaacagta tcttgtgtat
    19861 ccattgtatc ttctgttgtt tctggctgac gatagccttt tactgtgatg acaaattttc
    19921 catcagaaat atctcctcta tattgatata aaggatcatt ttctggtgta gccgtctcag
    19981 aatcataggt atcaaaagaa aaagtatctt ttattttttc ccataaagaa cggtcttctt
    20041 caccatccat ccgattttca tctgtttcaa catctatacc agacaatccg tcaaatccta
    20101 gtctagatgc tgcttcatca gtagtataaa taacgatatc atctcgttca tacccttcgt
    20161 tacgcaaccg ttcaattact gataatgctt cttccctcgt actatagctt ccgatgaccg
    20221 ttaaattttt ctcttccatg taaattcctc ctagcaaata gatttatgat tggtatattg
    20281 ttacttataa atttattcta taggagacga ttgttttcta caaatattta gattggaatt
    20341 tgattaaaac aatttaattg aaatttgaaa acatttatgt taatgaaagt catattctaa
    20401 taaaatgtca tttgtttcta tatgaatttt tatgaaaaat ttcatataat ttccactcgt
    20461 tgtgatggtt taatttatcc aatccatcaa taagcaaaca acttatataa aaaaggatta
    20521 attctcaata taattgctcc taccatagaa taaatcttca tgtaaagtaa tgaagtacca
    20581 actatttcta atacttcttt aagaattatc ccaacaatat cgttagacaa accattattg
    20641 aataaatgga gagccaatcg attctgaaaa aatgttttct aatttttcgg aaataaaaga
    20701 aagagcctcc tgccattaga acgaaccaaa tccatttcat tgctcatgaa gtaaccacat
    20761 agctaaaaag aggataaatc aattaaaaga tcaaaagaat gactgcacta ataaaataac
    20821 taaaaatgta tcttcttact tcatatcttt tagctagtac ttagttaaaa atttgcttcc
    20881 taagatcaag acaaactgtc tatcttcatt tgatgaaatg cggtaaaata tagaaaatga
    20941 acactattgg agggaatttg taatggacag caaaactaga aaacaactgc aagaaaagtt
    21001 aaagcaacgt acacacttgc tcccttccgt ctttcaacag tttttagaag aaaatcgttc
    21061 ttccctttca ttaggcagtc gctatgaata cgcaaaagat tttcatctgt ttactgatta
    21121 tttgagaaaa gtattttctg aagaagtgga tgatcagctg attatccatt tagaaaaaca
    21181 agattatcag aatttcttag ctaaaatcta tcgacatact cgttcgttcc aaactacagc
    21241 gaaccaagaa acggagcaat tgtttgaaaa tagctattac gggatttcaa ggaagcaata
    21301 ttcattaaat cattttttac gatttttgta tcaaaaagga ctgattgaag aagagatttc
    21361 tcttttgggt acaagtttac cggaaacaac caaagcagct ccgcgatata tcgatgcaga
    21421 acttttcaaa gattttgagc atttgtttat cccgattgaa ggctttcaaa caagcagaga
    21481 agctagcttt gaagaaaaga atagaccgag gaaccttgca attactgcca ttcttctgta
    21541 ttgcggatta aagatccatg aagtagtaga acttaaacgt aaagatgtat ctttgaccaa
    21601 gcagattctt aatctgaata gaaaagaaaa cagactgaat aaagtaccaa taccaaaaga
    21661 agcgatgcca tttctggaga actattttaa gttaacagca caaaatacgg acgaaaattc
    21721 ttttgttttt cgttcctcac atgatcagca aatttctcct cggactattc gccaaatttt
    21781 gagcaaaatt acagtatata aaaacgtatc gccagaacta tgcagaaaaa catatcgtta
    21841 ttatgcagaa ctatatttag atgatgctga cgcggtaaat tatttatgtg gtaatcgata
    21901 cctctcatcc cattcttttc aagatatctg ggaaaagatg gttgattttt cttatcacga
    21961 attagcggca ttcgttcggg tttcttccat ataaaacaaa tgtatgatct ttttttcaca
    22021 ataaactatg ttattatata aaggattatg ttacgattat cttgaatttg tatattactt
    22081 aacaaaagat aatggagtgt gaatgatgga gaccataacg tattcccctt tgaacttatt
    22141 tacgaatttt caagaagctg cagctaactt ttccgagacc ccgattatct ttgatgagcc
    22201 actttcagct ttcccagaat taggacttga aacaacttac aaaaaatgct gcgaaagtgt
    22261 gttgaaacgg gcttatcaat tggctcatct tggagtgaaa tccggagaca aagttattat
    22321 ttataagagt tccgcttttg acacatacct tctagctgtt tctgtgtctt accttggtgc
    22381 agtgcctgtc atgacttctt atcatctacc aacaacaaca atggaagtat ttatcgatcg
    22441 tttagaagac cctttcattt tatttgatga tgagacaaaa aagcgagtga gagaaatttc
    22501 aaatggaaca aaatcaaaac agattcctat tctttattta atggaacaac ctgctttgtc
    22561 tgtttctcaa tcatttttag acaaaaatga aatttcttat atgacccata cttctggtac
    22621 aactggtatc cctaaactta tttgtcattc tgctcattct atgggatggc ggacgaaatg
    22681 gcaaaaaaca gttttcacaa aaatttcgga aaagaaatta atcgcttttc acatctctcc
    22741 agtgcattcc agattcaata ttggtatctc ttctttgatg tccatgggat ttcctatgat
    22801 gcctttagca aacgcacaaa gttcaaaagt tgttcatatg ttggaagctc accggccaat
    22861 tgcactagag acccatccga ataactttgt tcagtggcgt tttactgcta aggagcatcc
    22921 agaagctttt tcgggtatcc gatactatca ctccactttt gatgctataa acaaccagac
    22981 aatgaagaca tttttgcgaa cgtcgatggc acaggatgcg gtatttcttc aagtatatgg
    23041 ccaaagtgaa tgcggaccaa tgattcttaa ggctcataca ctagagagtt tgaaaacaag
    23101 tgatgcaaga gatatgggcg ttggactgga agacatgaca agcgctcgga ttacagattc
    23161 agttgggaat gtcctacctg aaaacacaga tggtcatata caattactgt ctaaaggacg
    23221 ggctttgact tattacaagg aagatgcacg gttccaggaa aatgtttatg gcgattggtg
    23281 ggatagcgga gattacggtt ttatggataa gcatggccac ctatttttga aagatcggca
    23341 agtggatttg atcgaaacga tcaatagtac attagctatt gaagactttt tattagattc
    23401 gttagatttt ttggcagaag tagtgattgt aagggataaa aatcattctc cacaaccgat
    23461 tattgcttta gctcctgata aagaaatgga ttggaatcga tggtgggagc aagtccatga
    23521 acttcctcgc ttgaacgtcc ctatcatccg tgattttgat gcaatcccgc gaacagctac
    23581 aatgaaagtg caacggcttc aaatcgagaa agaattaaaa tcacaaaagt cctaactatt
    23641 taaggaaaga aagatccatt ttggtctttc ttttcttttt gtttttttaa attggatgag
    23701 ataaaaatat gccaattggc tgtttttctt ttttgaaaat ttcgttatac tcttattcat
    23761 ggaggaaaat gttatgaaaa gaatcttgac aattggcggt tctgatccat ttgctggtgg
    23821 aggaatccaa acagatttaa aaacttttga gaattttggt ctattcggac taagcgcctt
    23881 gacttctata ggggcactag atattaatga gcgatttatg ctggaatcta tatctttgga
    23941 attgcttaaa cgacagttag tttcgattga taaaatgact tcattagatg gtatcaaaat
    24001 tgggttattg aattcaagtg aagcaatcat ggttgttcga gacttcataa aaacaaaaca
    24061 aaatatccca atcattttag accctgtttt ggcattcaaa gaaactgaag ctgtgatcaa
    24121 tcaattgtat atttcgcagc tcatcgaaga actttttcca cttgttacga tgattacgcc
    24181 taatttggca gaagctgctt tactttctgg tcaagctctt ccctcttcgt taacagaaat
    24241 gatccatctc gctaaagaac tcactgcttc aggaacaaaa aacattgtga tcaaaggcgg
    24301 cacaaggatg gctggagatg aagctgtgga tcttctctat tcaattgatc attatgaggt
    24361 attttctcat aaaaaaatcg acactacaac agtaaacggg gccggttgtg ccttttcttc
    24421 tgcaataaca gcgaatcttg tgttaggggc agattttacc aaagcagtag cagaaagtaa
    24481 aaaatttgtt gcccattgta tttctaatgg cgtgctgatg aacgatcata ccggaagtgt
    24541 ctggtctggc ggtattcaaa aaggaggaat gagaaatgaa aactaagcaa ttaacgatct
    24601 atgctatgct gattgcgttg acagttgccc tttcattaac aattttgatc cctgtaccgg
    24661 ctacgaatgg atttgtgaca ttatgcgagg ccgggatcta taccgctgct tttctttatg
    24721 gtccaacggg tggattagtt gttggtgctt ccagtggtct attgatcgat ttgatttcag
    24781 gatatccgca gtgggcagtt ttttcattag tgatccacgg gttacaagga tatgttgctg
    24841 gttctttcag caaatcttct actcgtatgt ggggattagg gcttttatta ggaagcttag
    24901 ttatgatcat cggctatggt atcgccggtt ggattttata tgattggccg gctggagtgg
    24961 cttctatacc aggaaacatc ttccaaaatc tgattggaat gggacttgcc tttcctataa
    25021 ctgcaagtct tcaacgtatt caagcacgga agcaatatta attgaaaaag aaggttttag
    25081 aaaatgaagt tgtcagaaaa agaattaaaa gaccaattga ctgaaatagt taatgacata
    25141 ttggctgagg cacacttgaa aaaaggtgat ctttttgttt taggatgcag cacaagcgaa
    25201 gtcgttggag gacatattgg aaaaaattcc agtgcggaag ttggtcaatg gatcatccgt
    25261 acgttaaaag agttgttgga tcctaaagaa attgcgctag ctgtccaagg ttgtgaacat
    25321 ttgaaccgag cattagtagt agaacgaaca gtggcagaag caaaaaattt cgaaattgtc
    25381 tctgttgttc ctgcactaca tgctggaggt gcttgttctg ttgctgcttt tgaccagttc
    25441 aatgatcctg tcgaagtgga acacgtagtt ggacaagccg gtatcgatat cggtgacaca
    25501 tcaatcggta tgcatatcaa gcatgtccaa gtacctgtca gacctcgttt gaaaaccctt
    25561 ggacaagctc acgtgacagc ccttcgctct cgtcctaaat atatcggtgg tcctagagcg
    25621 aattattgaa atgagtaatt gacagagcaa tctgaaaaac ttcctcgcaa agtccaacta
    25681 atgaacttta acgaggaagt tttacttgtt tgttttatat aaccgagctt cataaggtgc
    25741 tagtatgcct ttagcttcaa attctccgct agaggaattt gacaagagta atgtccagga
    25801 ctgatctgct tcttttggaa gttcatagtc agcaagtgat tctgttaagt ttaccataat
    25861 aagatattgt tcatcttcta aatatctttc atagacataa agttgtggat gttcatgaag
    25921 atattcttta taagaaccgt atatcagacc tttattggtt tgtctaatgc ggatcatgtt
    25981 cttatagaat tgcaggaccg actctggttc atattcttgt tgttctacat tgatcgtttt
    26041 ggtatttgga ttagtgatca gccaaggttc atgtgtagaa aaaccagcat attgttccga
    26101 agtccattgc atgggtgtcc tgctgttgtc tctcgttgtt tcacgaatga tatccaatgc
    26161 ttcttctctt gtcttacctt ccgcaagcag ccttttataa agtcttttcg aatctactgc
    26221 atcaacttga tcgatcgatt caaagggcat attcgtcatt ccgatttcct gtccttgata
    26281 aataaatggc gtaccttgca aaaagaaata catcatagcg attgcttttg cagacatagc
    26341 ccaaaaatcg ggacgagtat ctccaaacac tgaaacggca cgaggaacat catggttttc
    26401 catatataaa gcgttccatc cgataccatc caatgaagtt tgccaagcgc ttaatgcatg
    26461 tttcaattta aggacatcta attgcccttc tttttcttgc tgccagatat ggatatgatc
    26521 aaattcgaat atcatatcga aataaccgtc tttccctacc cattgtggtc cttcttctgc
    26581 agtgacacca cttgcttctc cgacagtcat gatatcgtac tcttcaaaaa catgtttcaa
    26641 atcggtcaaa tgttcttcga ttcctgagac attttgaaag ggtgagaaag ggttctctgt
    26701 ggcttttact gaatattcat ctttttttac atgagaaatc gcatctaaac gaaatccatc
    26761 tatcccttta tccaaccacc atcggatcat attgaatagt tcttctttca atttctcgct
    26821 ttcccaattt aagtctggtt gttcttttgc aaaaacatgc agataatact gtccagtttc
    26881 atgagaatac tcccaagcag aaccgccgaa aatcgatgtc caattattcg gttctttgcc
    26941 atctaccccg tcgacccaaa tgtaataatc gcgatacggg ctttctttag attttttcga
    27001 ttcttcaaac cattgatgct gatccgaact atggttgatg acaagatcca taatcacttt
    27061 gatccctaat tcatgtgctt cttttagcaa taaatcaaaa tcttccatcg ttccgaatct
    27121 ctcttctata tcttgatagt cacttacgtc ataaccatta tcgacaaatg gagattgata
    27181 gatcggattg atccagataa agccgatacc aagatctttc aaataattaa gtttttcacg
    27241 gatcccattg atgtctcctt gaccatcgcc attgctatct ttgaaactag caggatagat
    27301 ttgatagcct actgcttctt tccaccattt ttgttcttgt atcatatcgt ttcactcctt
    27361 taacggtccc tcttgattat aaccgattct attttagaag tatccttgtt accggtaact
    27421 agaaacgaaa agctcaacga atctgctaag tgcgttcgtt gagctttatt ttatcataga
    27481 tagcgggcaa tcagttgaat catttgcttg ggaaattcat tcaagtcagt aatatctaca
    27541 aaacgacttt caccgtagat cgacttgatt tcttctttgt cttggccaat agctgcggag
    27601 acaaatagga ttccttgacg ttcatattct ttcaaaacag actggatatc ttcttttgct
    27661 tttttgcctg tataatccgg caacgctttt ggctgaccgt cactaatatt aagcaacagt
    27721 ttggttgttg cggattgtct gtttaatttt tctgctgcta aacgaagtgc agcaccatca
    27781 cgattgtttt gccttggttt catagtgact aatttttcat ttaaccattg aaatccgtct
    27841 tcaaattctt tataagaaaa caaagaagtc ttttctcttg acgaacggtc tgctgtatct
    27901 ccgtaaatca acaatgggat atcgactttc ttagaaaatt cggcaatggc aatcgctgct
    27961 ttttttgccg cttcgatccg atcatcccgt atcattgacc cagattcatc gatccgtaca
    28021 gctaccgcta aagaaggttg ctcatgtggc gggttctttt tgtcaaaatt tctcaaatca
    28081 ccatatgcta ctttgcttgc attgaaccgc tgaccttcgt attttccttt ttggtacgtc
    28141 tctgtttgtt cattatccag taactctaaa atttgccggc taagtgattc tactattggc
    28201 attacttgca tgtgtagctc acgtgcttcc ggcgtttttc cttggaaagc tggtcggtga
    28261 acgatgagac cttctttttc atgaatcgtt tccttcatga tttgtcgcgc ttctttattc
    28321 agttgcttct tgatttcctt atcatgtgct tccatgtcag aagcagacat ttcttgagaa
    28381 tcatctcctg tttgttgttc tttttgattt tttccttcga tatcgctact gcgttctttt
    28441 tgcatttgag gaggaatctc gtttttttct attgtttctt cttgtttctc ttctccctca
    28501 tttggttctt cagcagacaa cgatttcttt tcatctaagc gcagaatttc ttcagcattt
    28561 tcagtgatgt ttcgttcatt tgcttcttcg gcgctaatgg ttctttcttt tgtatgctca
    28621 gattgaggat gaccccattt ttcttttctc aatatgtcct gaagttccag tagcaatcca
    28681 ctgtcagaca aagcttgttc aagaattgcc aattcatctg aatcagtgga taatttatac
    28741 aaaacttttg gataaatcga ctggagtaaa tcttgtcctt gcttataggt atttgcccaa
    28801 taaaaataag aacgcattcc tgctacacct ttgatggcgt tagcttttgc agtttcatcc
    28861 aacaaacgga taatctctgc catctttaag agaagttctt gtttttggat catagttttc
    28921 gccatcgcac gttctgccat gacttctaag gcaggaagat ccattttttc cgcatgttgc
    28981 atccgatctc ttaaagattc atttaatggg cgatttcctt ggtaatttcg atttgtagtg
    29041 atcacaatga cgcaatctgg atggcgacga atgattcctg tcggtaaatt caacatccca
    29101 tttggttcga gcgctgagtt aagtgccaca agaacagagg catctcggat gacagtcggc
    29161 tcttgaatct ctaataaata gcctttttca atcgctcgaa cgatttcaga agggtaatag
    29221 ctgtaatgga ttgcatctgg ataatcagct tcgatccttt gaactagctc tgctaatttt
    29281 tctttagcag aaaaaggatc aatgccgtaa tggttctgga tcagtgtcag tacagcttca
    29341 agtgtatctg tttggtaaat agcttctagt aattcttggt cttgttcctt attagaatct
    29401 actacaggta ataaggctcc gaaaacatct gatttgtcca tatctgcaaa acaggtcact
    29461 tttgtatagg gaagttgcag atcagcagat agtgctttgg ctaattgtgt cttccccgac
    29521 ccggcatctc cttccaaaag tacgttactg attttcattt caggatcttg ccaattccct
    29581 ttgatttcgg aggcgatccg ccattcttct gcacttgtcc gatggctttt cggtttcttc
    29641 cagatcattt gcttttctag ccgtgaaaag gttcggtttt ctgttagtga gaaattctcc
    29701 atgcttctct tccccttttg atcatctctg tctattaata tcctagctca tctaaaagac
    29761 gttttaaaat acggaatcgt tccccaatca gttctccgtc tttttgtagt gtatcgtaat
    29821 acaaaatgat gtcttcatcg atctttggat ttttggtatc tacttctacc gtcattcggt
    29881 tcccttgtaa tccaatgatg tctacgactg gattttctgg atcataaaat ttttcataac
    29941 gataagcatc ttggaagtat aaacttcctt gcgcagctaa gatcgctaaa tctaaaatac
    30001 gtgtgattgg taattcttcc gactgtcgtg accatttttc tccagtatgt cgccatacct
    30061 tgcctgagat atcgactttt ccacgatcat tccactgagc aaggcccagt gaaagccctt
    30121 ttgcatccat atttaatgca tttcttccat caactttatc atagtcttct acaacgatta
    30181 ctggtttatg ttttaaattt gttggtattt ccattatttt aactcctcat ccttttattt
    30241 ttagtaaata agtaaattag tagtttactc atttactaaa ctatatgcga cattatagag
    30301 gattgaagtg aggattgcaa agaaaaagag cttcattgat agaaataaaa acaccatctc
    30361 gttcttttac acgctcatta gtaacatgta gaaagtccaa gatgatgttg gaat
//
LOCUS       DAXLPQ010000029        29879 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.029, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000029 DAXLPQ010000000
VERSION     DAXLPQ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.029"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(87..497)
                     /locus_tag="ACF3UO_001585"
     CDS             complement(87..497)
                     /locus_tag="ACF3UO_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3657616.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(678..1112)
                     /locus_tag="ACF3UO_001586"
     CDS             complement(678..1112)
                     /locus_tag="ACF3UO_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3657617.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTDNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(1212..2060)
                     /locus_tag="ACF3UO_001587"
     CDS             complement(1212..2060)
                     /locus_tag="ACF3UO_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3657618.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            2449..4215
                     /locus_tag="ACF3UO_001588"
     CDS             2449..4215
                     /locus_tag="ACF3UO_001588"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFD3657619.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            4317..5576
                     /locus_tag="ACF3UO_001589"
     CDS             4317..5576
                     /locus_tag="ACF3UO_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3657620.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            5723..7024
                     /locus_tag="ACF3UO_001590"
     CDS             5723..7024
                     /locus_tag="ACF3UO_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657621.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            7027..7878
                     /locus_tag="ACF3UO_001591"
     CDS             7027..7878
                     /locus_tag="ACF3UO_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFD3657622.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            7891..8706
                     /locus_tag="ACF3UO_001592"
     CDS             7891..8706
                     /locus_tag="ACF3UO_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFD3657623.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            8857..10023
                     /locus_tag="ACF3UO_001593"
     CDS             8857..10023
                     /locus_tag="ACF3UO_001593"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3657624.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            10253..10900
                     /locus_tag="ACF3UO_001594"
     CDS             10253..10900
                     /locus_tag="ACF3UO_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFD3657625.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            10984..11928
                     /locus_tag="ACF3UO_001595"
     CDS             10984..11928
                     /locus_tag="ACF3UO_001595"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFD3657626.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            12063..13514
                     /locus_tag="ACF3UO_001596"
     CDS             12063..13514
                     /locus_tag="ACF3UO_001596"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFD3657627.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLIRSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            13535..14371
                     /locus_tag="ACF3UO_001597"
     CDS             13535..14371
                     /locus_tag="ACF3UO_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3657628.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            14371..15030
                     /locus_tag="ACF3UO_001598"
     CDS             14371..15030
                     /locus_tag="ACF3UO_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3657629.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            15156..15845
                     /locus_tag="ACF3UO_001599"
     CDS             15156..15845
                     /locus_tag="ACF3UO_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657630.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            15851..16807
                     /locus_tag="ACF3UO_001600"
     CDS             15851..16807
                     /locus_tag="ACF3UO_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFD3657631.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            16851..17363
                     /locus_tag="ACF3UO_001601"
     CDS             16851..17363
                     /locus_tag="ACF3UO_001601"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3657632.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(17619..18167)
                     /locus_tag="ACF3UO_001602"
     CDS             complement(17619..18167)
                     /locus_tag="ACF3UO_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFD3657633.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(18256..19437)
                     /locus_tag="ACF3UO_001603"
     CDS             complement(18256..19437)
                     /locus_tag="ACF3UO_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFD3657634.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(19673..21181)
                     /locus_tag="ACF3UO_001604"
     CDS             complement(19673..21181)
                     /locus_tag="ACF3UO_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFD3657635.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            21340..21531
                     /locus_tag="ACF3UO_001605"
     CDS             21340..21531
                     /locus_tag="ACF3UO_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657636.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            21734..22651
                     /locus_tag="ACF3UO_001606"
     CDS             21734..22651
                     /locus_tag="ACF3UO_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFD3657637.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            22644..23717
                     /locus_tag="ACF3UO_001607"
     CDS             22644..23717
                     /locus_tag="ACF3UO_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657638.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            23865..24383
                     /locus_tag="ACF3UO_001608"
     CDS             23865..24383
                     /locus_tag="ACF3UO_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657639.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            24364..24756
                     /locus_tag="ACF3UO_001609"
     CDS             24364..24756
                     /locus_tag="ACF3UO_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFD3657640.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            24832..25767
                     /locus_tag="ACF3UO_001610"
     CDS             24832..25767
                     /locus_tag="ACF3UO_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3657641.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            25900..26679
                     /locus_tag="ACF3UO_001611"
     CDS             25900..26679
                     /locus_tag="ACF3UO_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFD3657642.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVFFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            26672..26989
                     /locus_tag="ACF3UO_001612"
     CDS             26672..26989
                     /locus_tag="ACF3UO_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFD3657643.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            27233..28843
                     /locus_tag="ACF3UO_001613"
     CDS             27233..28843
                     /locus_tag="ACF3UO_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3657644.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            29000..29848
                     /locus_tag="ACF3UO_001614"
     CDS             29000..29848
                     /locus_tag="ACF3UO_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3657645.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         9707 a         5325 c         5886 g         8961 t
ORIGIN      
        1 tacttgatta actaaatata gatcttccat ttttccacct ccgctgtttt actatagtgt
       61 atcatagcgg atttacacaa aaaagtctat tcactaactg ctttcagagt aacttctata
      121 tttccagctg tagcttttga atacggacac actttatgcg ctgcctctaa taattcttgc
      181 gtttcttcca gagaaagacc ttcgatagat ccttcaatct ctacacctaa gacaaagctc
      241 gtttcacttt ctgaataaag ggaaacttgt gcactgacag tagaagcccc agagatattt
      301 ttttgctgtt tgatcaattc taatgcactg ttaaaacatg cactgaaacc agctgcaaac
      361 aattgttcag ggttggttgc attttcgacg cgtttaccag gagctgcaat attcaattcg
      421 aatgtacgat cgggattatg aacttctcca gagcgtccgc ctgtgttgat cattttcgta
      481 gaatacattt ttttcataaa attaccacct ttaattatat tttatacaat tgaattttac
      541 acaatataat tgtggaaagc aaagaaatgg attggcataa gataaataag agaaagcaca
      601 tgaaacagac gcgctttctc gaatagcaaa catatacaaa aaaatatcag agacaaaaac
      661 taatctcatc ataaacatta catatatttc tcaaaaagtt gttttctttc ttcaaaactt
      721 acttcacgat ggacctgatg aagcatccat aaataaccaa aaggatctct gaacattgag
      781 ttagtcacac caaagtccat catttctgtc atttcttgaa tctctacaca gccatttcgt
      841 aatgctttat tatctgtgtc ctcgatatca gagacgatga tattgaacca gatcgtattt
      901 ggatgttcag cagtaggagc agtcaaacca agagacgtgt tttcatccag catatggaat
      961 ctcgtgccat acaaggtaaa aatgacttca ttattgcctc tagggtaatc tgttgcctca
     1021 atcagttgta tttcatcaaa gattgtttga tacagttcta gtgctttcaa actatcattt
     1081 aatacaaaat ctatttccgt tcctttatgc ataaagatct cctctccttt tcagtcgaac
     1141 agttactaga ttcttttatt ataccagtta aagaaaacgc attcaaaaaa atagcggatt
     1201 tacttaccaa ctcattcgat tggatgataa gtaaatccgc gtcccattac ttctgctacg
     1261 ctgctgacaa tgacaaaggc acttggatcg atttcttcta tcaatggttt cattcgggaa
     1321 aattcatgat cagtcacaac gatcaataaa acctcttttg actttcgatt atacccgcct
     1381 tttgcctcta gcagggtaag gccacgtcca atctcagcac ttaagcgaag gcggatgtct
     1441 tccaaataat gttcactcat gaccataaca gatttctttc gattgatacc tgtttcgata
     1501 taagtcatga caattgaagt gattgcaata gataaaatag cataaagaaa ctcttctatt
     1561 ccaaaaacaa acagattaag agaaacaacg aatgcgtctg taaaaaataa gccaatcgaa
     1621 gtattcaagt ggaaatattt tttaaaaatg aggggaggga tcgtcgtacc gccgctagaa
     1681 gagttgtttt tatataaaat cgcaactcct aaagcaaaaa tcgcacttcc aaaaatgaca
     1741 gacaacaacc gatctgaagt aatcattgtt tctggaacta ttgcaatgat taaaggaaaa
     1801 aacaagcttc cgaaaagtac tttaaaaaag ggttttttac ctaaaaatag aagagctagt
     1861 accaacataa cgatattcaa cactaaaata actatagctc ggtcaaatcc taaaacagct
     1921 tccagtaata ttcctagacc gctgacacct ccagcagcaa tatgatgagg ccctaaaaac
     1981 atattgatag cgactcctaa tatgaagagg gcaaaaataa tcttaatgta tgtccatata
     2041 aattgtctcg tttctttcat ttatccactt ccttaattca ttaataatac tcttatctta
     2101 ttataactta cttttcacct taagttaact ttaattaata aaaaaattag gctagtctaa
     2161 attattatgt ttcattcttc tagaatatac ttctacgtta aaaactgtta aaaaactttt
     2221 actttagaaa attggagaaa ttgatcgctt aagataaatt caggacacta aatagtacag
     2281 gaagtagatt aaaactttta aaagttttaa gtctatctat ttggcaagtt taaaaaataa
     2341 aaattcggta tcaaaaaact gttaccgata acatttttga aagcgttgtc ttttgtttct
     2401 ctatcactta tagtgatgac gtcatattaa aacacaagga ggaaatcaat ggatacagct
     2461 gcaatttatc atcgaccgga aagtgaatat gcatttctat atacgaatac aagatttcgt
     2521 attcggcttc gtactaggaa aaatgatatc aaaaaagtat atgtgctttg tggagatcca
     2581 tataccataa caactgaaaa atggtatcaa aaacaacgac caatgaaaaa atgtctaagt
     2641 accaatgttc atgattattg ggaaattgaa gtgacgagcg aaacaaggcg cttacagtat
     2701 gcgttccatg ttgttgggga agataacacg gactgttttt acggtgatca aggaattttt
     2761 ccttatcgag aaaatgtgat tactgaacca aatttttatt ttcgaatacc ttattttcat
     2821 caaatcgatc gattcactat tccagaatgg gtaaaagaaa cagtatggta tcaaattttt
     2881 cccgaaagat ttgcaaacgg ggacaaagca aatgaccccg aacacacttt accttgggga
     2941 agtaaagatc cagaccgaga agacttcttc gggggagatt tgcaaggtgt gagggatcat
     3001 ttggattact tgacggacct tggcgtcaat ggcatctatt tttgtcccat atttaaagcc
     3061 acatccaatc ataaatacga tacgattgat tattatgagg tggatcccgc ttttggcgat
     3121 aaaaaacttt taaaaaactt gattgatgaa gcacataaaa gagggatacg tatcatgttc
     3181 gatgctgtat tcaatcatat gggtgtccat tcaccacagt ggcaagacgt tctcaaaaac
     3241 ggagaaaaat cgatctataa agactggttc cacatccgtt ttttcccagt agattcttat
     3301 cagatgactg acttaccaga aactgctgaa aatatcccat atgatacttt tgcttttact
     3361 ccattcatgc cgaaactaaa tacagcaaat ccagaagtgc aaaaatattt gctggatatc
     3421 gcaacttatt ggataaaaga attcgatatt gatggatggc gtcttgatgt tgctaatgaa
     3481 gtcgatcatc atttttggaa aaaattcaga gaagcagtta cagaaatcaa accagacatc
     3541 tatatccttg gagagatttg gcattcctct caagcttggc tgcaagggga tgaattccat
     3601 gcagtgatga attatgcatt cacagattcg attaaagatt attttgcaaa aaagaaaatc
     3661 acagcttcac aaatggtcag tggaatgaat catcagcaaa tgctttacag agatcaggtg
     3721 aacgaaggaa cattcaactt attagattct catgatactg ccaggatctt gaccctttgc
     3781 caaggtaaca aagaattgat gaagtctgtg atggccttta tgtttcttca aaaagggtct
     3841 ccttgtatct attacgggac agaaataggg atgactggtg aagatgaccc ggattgccgc
     3901 aaatgtatga tatgggagaa ggaggaacaa gatctagagc tattcggttt tataaaagaa
     3961 cttgtttctc taaggaaaca gttgtctaag attatttctg aaggttctac tcagtggcta
     4021 atagtatatg atcgtgaaga taagctctat ttcacacggg aactagaggg acagatcatc
     4081 tatgtttact ttaatcagtc aaaagaacct tgggtagtag aacaggaaaa tgaggtgatt
     4141 cttagtcaaa attgtcagtt gttagaagac gggaaagcag agatacgaca atacggattt
     4201 ttgatcatgt gttgaaaact gttaccggta acaacaagaa agcgtttgca aatgaagatt
     4261 tgtgcccatt ataataaggg tgtaacagca cgttgaatac acaggaggaa atgaagatga
     4321 aaaaaagaag tgtgaaacag ttgggtttag ggttaatctc tttaggaatc ttaggcggat
     4381 tagcggcttg tggcaatggt aactcttcag cagaagggga agccgatgaa ggaaaaacgt
     4441 taacagtttc cgttgattct ggatataaag attatataaa cgaaataaaa aacactttcg
     4501 aaaaagaaaa cgatgtgaaa atcaagctag tagaaaagga catgttcgat cagttggaat
     4561 cattagcgtt agatgggcct gctggaaagg gacctgacgt tatgatggca gcatatgacc
     4621 ggatcggtgc gttaggacag caaggacatc tggcggaagt aaaactggga aatgaagcag
     4681 cttacgatga aacagacaaa gcccaagtga cttatgatgg aaaaatctac ggagaacctg
     4741 cagtaatcga gacccttgtt ttgtactata acaaagattt agtcgataca gcaccatcaa
     4801 cgtttaaaga tttggagaat ctatccaaag acagtcgttt tgcttttgag tcagaagcag
     4861 gaaaaaatac aggattttta gctaaatgga ctgactttta ttattcctat ggtttaattg
     4921 caggttacgg tggctatgta tttggtgatg atggcacaaa tccttcagat atcggtttga
     4981 ataatgcagg tgctgtagaa ggaatctctt atgcaacaga ttggttcaaa aatgtttggc
     5041 caaagggaat gcaagacata aaaagtgcag gagacttcgc cagccagcaa ttcatgtcca
     5101 ataaaactgc agcaatcatt gacggtccat ggcaagcgca aacatacaaa gaaaacaata
     5161 tcaattatgg tgtagccaaa attcctactc taaataatgg acagccttat caaccgtttg
     5221 gcggaggaaa aggatgggta gtcagcaatt atgctaaaaa caaagacctc tctcaaaaat
     5281 ggcttgatta tgtaacgaat caggaaaatc aagaaaaatt ctttgaaatg gtaaatgaaa
     5341 tccctgcaaa ccaacaagct agggaaacag caaaggctaa aaacgatgaa ttaacaacag
     5401 ctgtgattga acaatatgaa acagctcaag cgatgccaaa catcccagaa atgggcgaag
     5461 tttggacagg tgcagaaaac ttgatgttcg atgcagcatc aggttcaaaa acaccaaaag
     5521 aatccgcaga tgaagcagta aaaacaatca gtgaagccat agaacaaaaa tactgattaa
     5581 aatgataacc gtccattttt ataaaaaatg gaacaggtgc ttcagataaa agtggcaaga
     5641 gcgagatgga aaattatctt gctcttgttg ccattatctt aaaagcagtt tgcggtttag
     5701 caagtttaga gggggcattc agatgcagca agataaaaca agcaatatca acgaaaaaaa
     5761 aatcacgctt tgttcactta ttccagggat ggggcagttt gtaaatggcc aagcttttaa
     5821 aggtatcgtt tttttcgcca tattcgtcct attcattggt cagatgcttc tgggcggatt
     5881 tcatgcattg gtaggattgg ttactttggg aagtatacca atggaagatc attcattatt
     5941 tattttgatt gaaggcactt tgcaattcat cattacaatc attttcttga ttttttacgg
     6001 tttgaatctt ttagacgctt atcgagtagc gaagatgcgt caagagggca aaaaaatcaa
     6061 tcggacgatg aaggaagtca tacataatat aggtgatgaa ggttttcctt atctattgac
     6121 acttcccgct tatcttctca tgatttttac gatcattttc ccagtcctag ttacattgtt
     6181 cactgcattt actaattatg acttcaatca tattccacca gccagtttaa ttgattgggt
     6241 aggggctaaa aactttttta gtatcttctt tttaagctca tatcgtaata ctttttttgc
     6301 agtcttttcg tggaccgtga tttggacttt atgtgcaaca actttgcaaa tcacccttgg
     6361 tattctcaca gcggttgttg ctcaccagaa atttattaaa ttcaaacgta ttttcggtat
     6421 cattttctta ttaccatggg cggtcccagc ttttattact atcatgagtt tttcgaatat
     6481 attcaacgat agcgtaggtg ccatcaatac tcaagtgatt cctttcataa accagcttcc
     6541 ttttgtagat atcagtgcaa tctcttggaa aacggacccg aactggacga aagtagcaat
     6601 tatcttagtg cagggctggt taggatttcc ctatatctat gtgatggtta caggaatctt
     6661 acaatcgatt tcagaagact tatatgaagc agcaaaaatc gacggagcaa atgcatggca
     6721 gcgcttttca aacatcacgc ttcctgctgt cttcctagtg gcagcgccaa catttattac
     6781 acagtatacg gggaatttca ataatttctc catgatctat ctgtttaaca atggtggtcc
     6841 cggaagcgta ggcggaggag ctggttctac tgatattctt atttcctgga tctataaact
     6901 tacgactgga acttctccgc agtattctat ggcttcagca atcacgttga ttatctccgt
     6961 catcgttatc tgtgtgtcat tgctggtatt taaaaagaca aatgcgttca atatggggga
     7021 ttaacaatga aaaaatttca ttcgagtgct cgattccaaa aacgactttc tcactttttt
     7081 acttactttt ttcttttaat actgtcagtc attatcatct atccgctttt gatcacagca
     7141 agtactgcct tcaagtcagg aaatattgca gcttttagtt tagatctttc aagtgactgg
     7201 actttaggaa actttactcg gctattcagt gaaacacttt acgggacttg gtataaaaat
     7261 acattgatca tttctgtcct aacaatgatc gtacaagtga ctgtagtaac tttggcgggc
     7321 tatacttata gtcgctatcg ttttatcggc cgcaaatcaa gtttgatgtt ctttttagtg
     7381 attcagatgg taccgactat ggcagcattg actgcctttt atgtcatggc tttcttatta
     7441 gaagcgctcg ataagtactg gttcttgaca atgatctata taggcggtgg aattccaatg
     7501 aatacttggc tgatgaaagg atactttgac actgtaccaa tagatttaga tgaatctgct
     7561 aaacttgatg gggcagggca tttcaggatt tttttccaga ttgtattacc gcttgtcaaa
     7621 ccgatgctcg ccgttcaagc attatgggct tttatgggac cttttgggga tttcatgtta
     7681 gctaagttcc tgcttcgaac acctgaaaat cagactgttg ctgtcggctt acaaacattt
     7741 atttctgatg tgacaaacca aagagtctct ctttttgctg ctggggcaat tttgattgca
     7801 ctaccgattt gtctattatt cttcttttta caaaagaact ttgttaccgg cctgacatct
     7861 ggcggaacaa aaggatagga gcagagtatc atgcaaacat ttccgttaaa ctatttttcc
     7921 gcattacgta cgccaactca agtgtttgcg ggacgcaaac tattatcatg gcctaaattt
     7981 ttcttgatat ttgtattttt agtttccttg atggtcatgc ctgtgactct tttttatgcc
     8041 aatcagatcc aagcgattcc attagaacaa tttctatccg ttcattcgct gatcgatgaa
     8101 caaggaaccc aaaaattttc tgaacttgaa ttatctgaaa ctgggttaca agcatcgcaa
     8161 caaacgatag ctgtgacccc tgaaattttg gtaggtgtgt ctttatctga gaaacaacaa
     8221 tccgatcatg gaacttttat tgattttgag aaggaacaat gggtgatcca acaaaaggat
     8281 aaatctggta tacgccgcta tacgatgaat tatagcccat ctttccaacc agattctgta
     8341 cgtacgcccg aagatttcca acgattttta gaaagagaat tttatgccag taatcgtcca
     8401 acaatcattt tatcttatag tttaagtctt ggtcttgtcc tatttgtcat gacgagtctc
     8461 attttattcg gggcttcctt tttcttgtgg atgacaagaa aaagccaact ttcatccatt
     8521 catacattca aagagagtgc aaatttgatg ctgaatgtta tgggaatagg ttccatggca
     8581 gcagcagttg tagggtttat ccactttgac tttatcttga tgctaagtgt ccaaacaacg
     8641 ataactgtct tgctgctttt atgggttttt gtcaaaacaa gattcaaaga taagcgtgtc
     8701 gaatgacaag tttaagcgat ttatgcgaca atgaatgtga aaaaaatgaa aaataaagta
     8761 gtttttgaaa aatttctgaa aaaattaaac ttcttagttg attcttttct tttttagtat
     8821 taacgtaata gggtagtttt tttaaggagg aaaatcatgt tagagaaaac tttatacaat
     8881 caattatttt cacgttcttt ctcgctccct gtcgaagtaa attattggga cggtacaacg
     8941 aaacaatacg gagatacgga cactcctccc caaatcaaaa tcaatatcca tgaagaaatc
     9001 ccaatgaaag agattacaag taacgcttct ttggcactag gagaagccta tatggatcat
     9061 cgaatcgaga tcgagggaag tatccaagca ttgatcaacg atgcttatca gcaagcaaac
     9121 agctttttac gaggaaaaga ttatctaaaa tggctgccaa agaaagaaaa acatacgaaa
     9181 caaaaaaaca aagaagatat ccatgcgcat tatgacttag gtaacgactt ttataaactt
     9241 tggctagatc caactttgac ttattcttgt gcttatttca atacacctga agatacgttg
     9301 gaacaagcac aaatcaataa agtccatcat atcttagaca aactctttat caaagaaggc
     9361 gaaacgttgc ttgatatcgg ttgtggctgg ggaacattga tgttcactgc taccaaagag
     9421 tataatgtca aggcaactgg gatcacacta agtgaagaac aatacgattt gattaccaaa
     9481 agaataaaag aagaacattt agaagataaa tgccgtgtat tattaatgga ttaccgcgaa
     9541 ctaaaaggcg aaacgtttga tcatatcaca agtgtaggta tgttcgaaca tgtaggttct
     9601 gaaaatcttg aaggttattt caaagtggta aaagatttat tgaaaccaaa aggaacagct
     9661 ttgatccatg gaatcagccg acaacaaggc ggtgcgacaa atgcttggat caataaatat
     9721 attttccctg gcggttatgt ccctggtgtt actgaattag ttgataatat tacaaaaaac
     9781 gatttgcaac tgattgattt ggaaagctta cgtcgtgact accaattgac attagaacat
     9841 tggacaaaga attttcatca agtccaagat caagtcacga aagaaatggg tgattccttc
     9901 tatcgaatgt gggatctata tttacaagct tgtgcagctt catttgaatc aagtaatatc
     9961 gatgtgattc aatatttgct tgttcaacct ggaaacaatg acatcccaat gcatcgtgca
    10021 taattgaggc aaaagtactg tttaaagact atttaaaaag aagctaagtt ttatgatgct
    10081 ccagaagtga acttttttgt ctaacttcta ggattgtctc taaagcttag tttctttttc
    10141 tttatatttt cataataaaa gtttggttct ttaattttta aacatgacag aaaatttttt
    10201 cttcgttata cttgtaatag aatactattt tataacaaag gggatcgaat caatgaaaaa
    10261 aactgttatt tatactagtt tatttgcagc tttgttttta gctgcttgtc aatcaaatac
    10321 caatcaaggc acatctggga atacgtcttc cagtagcgaa cagcgctctt cacaggtatc
    10381 ggactcctca acaaaagcaa gcacatcttc gtctagccag acaaaaagtt ctagtgaagc
    10441 aagtactcag tcagatatca aagtgtctgc agctcgtgcg atcgaattgt tccaagataa
    10501 atacccagat actgcaatta ctagtttgga attagatagt gattggggat cttacttcta
    10561 caagatagaa ggtgtcgatg atcaaaaaga atacgaagca agaattgatg ctcaaaatga
    10621 aaaaatggag acagagaatc cagaaactct agatcgagat gaacaaaatg gtcaaaagaa
    10681 aaaagaagat ggtctggatg ttgataaatt gatcacgatt gaggaagcag caaaaatcgc
    10741 cgtcgacaaa gtaggaagcg gtacggcaac agattgggat ttggataaag atttaggtac
    10801 tacttattgg gaagtcaaag taaaagacgg caatcaaagt acatcagtca agatcaatag
    10861 ccaaacaggc gaagtactgt caactgaaca agatgattaa gaatttcttc ggaaaacaag
    10921 agttgatttt tcttttagtc atgatacact agacaaaata acttgtttga aggagcgatt
    10981 tacttgagtt tagaaacgac ctttgccaat catatctttg ccaatccttt gatgaatgca
    11041 tctggtgtcc actgcatgac tacccaggaa ttagatgaac tggctcattc agaagcagga
    11101 gcatttatca ctaagagctg tacgatcaat gaacgaaaag gaaatcccga accacgctat
    11161 tttgatgttc ctttagggag tatcaattct atgggacttc caaacttagg tttttcttat
    11221 tatctagagt atgctcttgc gtatgaaaaa gtgcaggaaa accaaaatca accgttattt
    11281 ttttccattg ccgggatgag tgtccaggaa aacttggaaa tgcttgagaa aatagaaaaa
    11341 agtgggttta atgggatcac tgaattaaat ttatcttgtc ccaatgtgcc tggaaaacca
    11401 caactagctt acgattttga ggccacttat gaaacactga aagaagtatt cagcatcttt
    11461 tctaagccgc taggaatcaa attgcctcct tattttgatt ttgctcattt tgatcagatg
    11521 gctgatatct tgaatcagtt tccattgacc tatgtcaatg ctatcaacag tgtgggcaat
    11581 ggtttgtata tcgatacaga acaagaagca gtagtcatca aaccaaaaga agggttcggc
    11641 ggcattggcg gagagtatat caagccgact gctttggcga atgttcgcgc tttttataca
    11701 cgtttgaaac cagaaatcca aatcattggt acaggtggga ttcggacagg acaagatgca
    11761 tttgaacatc tgctatgtgg cgcaagcatg ttacagattg gtacagagct tcataaagaa
    11821 gggccggaaa ttttttctag aatcataaaa gaattaacgc agattatgtc agaaaaagga
    11881 tatacgtcaa ttgacgaatt taaaggcaaa ttacgcacca tttcatagca aagagacgaa
    11941 ggtcatgatt gatcttcgtc tttttttata aaaaacactc gtctgttcat tcctgtgcaa
    12001 gcgtactcat tgtatgttag acgaacttgt gggaaaataa cagaggcaaa aaggaggata
    12061 atatgaatga tgcaacagaa ttagcaaaag agcttaaaga aaaagaattt agttttcaag
    12121 aactagttac ggatatacag aaaaaaataa agaagcaaaa tcatgaattg aatgcgtttg
    12181 tcgcgcttga accattcgag agtaattccc acgagctatt gattccccag tcagaaaaag
    12241 ggccattggc tggtatccca tttcctttaa aaatgctcgg tcaagaaaaa aagggatggc
    12301 tagctacttc aggatctcgt ttatttgaaa cacaccgagc ttctcataca tctaattatg
    12361 tgcggcaagc agaagcgata ggtctagttc cttttggaca aaccaatgcg ccagagtttg
    12421 gtttcaaaaa tattacagac ccagtcatct atggcccagc aagaaaccct tggaaccttg
    12481 aatgtacacc gggcggatca agtggaggag ctgctgctgc agtttcatca ggaatcgttc
    12541 ctttagctgg tgctagtgat ggcggtggtt ctattagaat acccgcttcg ttttgcggat
    12601 tgattgggct gaaaccttcg cgagggacga tgccagttgg tccatatgct tggagaggat
    12661 ggcaaggagc tgctattgat ttcggcttga cagtttctat gagagacacg gaggctttat
    12721 tttatgggat gagaagtatc cattccggtg cgccatatca agtatcgcca gttgagtggc
    12781 aaacacatcc aagaaaaaaa cggttgaaga tagctttttg tgttgattca ccgatccact
    12841 cacagattag tgaagaggca gtacttgctg taaaaaaagc tgtagatttc cttggaaaag
    12901 aagggcatga tttgacagag attccttacc cactagatgg tcgtaaactg atcaggtctt
    12961 attatcagat gaatggcgca gaaacagcag caatgatccg ctcgattgaa acaggcatcc
    13021 agcgagctgt cagaaaagaa gaacttgaac ccatttcttg gactttgttc caatatggtc
    13081 agaagctctc tgccgctact tacatcgatt ctctgcatgt atgggatgaa gcagcaattg
    13141 tcatggaaaa cctacatcaa gaatacgatc tattcctttc accaacgact gcatttaccg
    13201 cccctaaaat cagcgaagat ttgcaaagtg atgcgataag agcacagatg gaacacatca
    13261 gtgattgttc tgaagtagaa ggtttagacg ttgtttcttc catgtttgag gagagcttga
    13321 agatcacacc ttatacacag ttggctaatc tgactggaca accagcaatc agcttgccta
    13381 ctcatttgac aaaagaaaac atgcctctag gaatccaatt tatggctgcc agaggaagag
    13441 aagatttgct atttcaaatc ggctatctat ttgaagcaaa tcatcagttc catttaccaa
    13501 atccatggaa atagcagaaa caaggagaag aagaatgaag aaaaaaagat tgtttgctct
    13561 aataactagt gcctttttta ttttaagcgc ttgcggtaca gctgccgcta atcaggaaga
    13621 taacagctgg agtaatgtag aaaaaaagaa agaattagta gtagcgactt ctggcacact
    13681 gtttcccgca tcttattata atgatcaaaa tgaattagtt ggttatgatg tagatttggc
    13741 aaaagaggtg gctaaacggt taaatgtcaa aatctccttt aaagaataca acgtggatgg
    13801 acaaatcact tctgtttcaa aaagagaatc agattttgct gcgaacgatt ttggtatcac
    13861 aaaagaaaga gaaaaaaaat tctccctttc agagactttc aaatattcat ttgacagtat
    13921 gatcgtacga aaaaaagatg attcaggaat ccactcactt gaagatctta aagggaaaaa
    13981 agcagctggc gaacccaata ctagctatat gcgtttagcg gaaaaacacg gagctaaatt
    14041 agtcacatat gacaatgcca cgaatgatca gtatttaagc gatgtagcaa atggtcgaac
    14101 agatgttatt ctaaatgatt attatctgca gaaaatggcc gtatctgctt taccagatat
    14161 ccctgtaaaa atactggaga acgtttattt caatgaaaac gaaagtggtt ttttattgaa
    14221 agaaggaaat gatgctctga aaaagaaaat cgatggcgta ttaaaagaga tgaaagaaga
    14281 tgggacgaca aagaaaatat ctgaaaaata ttttcaaact gatgtttcag tcaaaccgaa
    14341 agaaacgatg gctgagtcgg tgagtgagtg atgtactttc ctctaattga tttttccctc
    14401 atgtggactt cacttccttt cgtactgcaa ggcttggtat acacattagg gattggcttc
    14461 gtgtcgtttc ttttaggaaa tttggtaggg ttgcttttga cagttttagg tcttttggat
    14521 tggctgcctc tgaatgtatt tattcgtttt tatttatcgt tctttagagg cattcccgca
    14581 ctagtcctgc tgtttctgtt atatttcggg ttaccttatc aattaagtgc cttaacggct
    14641 tcagtcatct gctttacgat taccagcagt gcatttattg gtgaaatcta tcgaggatca
    14701 ctagcaggcg tttcttcagg tcagtgggac gctggtttag cttctggttt ttctttcttt
    14761 ggggtattga aatatatcgt tttgccgcaa gcttttcgaa tctcagtacc ggcactcagt
    14821 aacgtagcta tggatctagt gaaaggtact tcgttagcag caacaatcac agtgccagaa
    14881 atatttcaaa aagcaaagat cataggcggt cggacattcg attatttttc tctctatatt
    14941 ttagttgcac tgatttattg ggtcatttgt atcgggatcg aaaaagtgca acagtattta
    15001 gaaaaacgtt ctatccatca gtcaatctga aaaatagaaa tggtgctagc gtggctggca
    15061 ccatttctat tttttgtttc ttgtatattc tgcctagtat tttaaaacca tttcatgtaa
    15121 aatgtaaatc gaaaatatgt tcggaggtag aaaacatgaa gaccccgcta accatcgaaa
    15181 tagaatcctc gttataccaa tattgcatcg agcaaggcgg cttggttgta gaagaagtca
    15241 cgatgcctga tgaccaagga attgtagata cgcttagctg cttgacaaaa tttgatggaa
    15301 gccgagaatg gcgatgctat gagctgaaag tgacaaaagc agattttcgc tctacagcca
    15361 aactgtcatt tgttggacat tataattatt ttgttttacc aagtaaacta tatgaagaag
    15421 taaaaactga aatccctaca ggaataggtg ttttagtgta tcgtccgtac acggttgaag
    15481 aggagatgcc tgcctctggt acatttctga ttgcgaaaaa agcagcaaag aaagagcttg
    15541 ctgtaccgga agaagctttg acaaaccgct tcatggcttc tttattcagg gaagtaagaa
    15601 aagcaaagca aatggagcga ggcgtaaaat attttccaaa agatcaattg tacaaagaat
    15661 tgaaaagacg ttcagaaaat caagatccat tttctaacga acgatattat gaacggtttt
    15721 tagaggaaat agctagtcag gcaatcaatg agttgcaaga agaagttatc gcgcttcagc
    15781 atgattatga atatttgagg caacaacagc agatccgtcg gttgcctaca gagccattgg
    15841 agtgaaaaat atgtactatc cttatttaag aggaaaacaa tttgacctat tagcattaaa
    15901 agaagcactg tcgcgaggat tgctctccaa taaaatccaa ccagtgatcg aaccagtacg
    15961 tgattccgct acgcttaaaa atgtgatcga attatttcaa aaaaagcacc atccaatcgc
    16021 tgtgatccaa aatccccaag taggacaatt caaattattc gatcagcatg tgcacagttg
    16081 gacagtcaaa gaaaatagct ctgtcgtccc tgcacagatc ttaacgccag aaaatctcag
    16141 tgaagtactg gattcacctc cagcgtttct tgttttcgat ggacagcact acccaaaaga
    16201 tacagaggtg tggaaacagt tggcaggagt tgattcgaaa tttttgatac cagatactag
    16261 tcgctttcgc atctggctgc ccgaaaacaa aattgtgatc cgtgactctt ttcaaacgag
    16321 aaagcatgtt gaaagttatg cagataaaac agatgacttt tttagtgatg actatctttt
    16381 tttccacgca gacggatata ttggattttc tgatttcacg atcgaaggta gccgttattt
    16441 cgataaaggg ttccctagcc gagcgcttgc tatccatcta acgtatattg atgcttacgg
    16501 caatatacgc gtgaaacatt ttgtctctga cagtaacgac tctgctaaag accaagcatt
    16561 gaagtttctt gaagcaggag ataaaatgaa aaaatggatc atgcgtcacc atcatcaact
    16621 cttgattact tcaggaatga ttgaattatt ggctctttac cagcaacaaa aattccctgg
    16681 actgggagtg ttgaaaaagt ggtcacttat gcatcatttg gaacttatta gtcacctgct
    16741 agatcatcca aaagattggc ttaaatatta ttcaaaagtt caggaactat atgaagtgat
    16801 ccaatgatta gataatgtaa atgaaaaagg aatagaaaag aggaaactgg atgtatattc
    16861 ggcaaacaag gaaagaagaa gtagaagaag tggtagaaat cattaatgcc gcagcggatt
    16921 tcattgcttc gcaaggctct cctcaatggc aaaacgggca gaaaccaaca aaagaaacga
    16981 ttttgaacga tattgaaaga aaagaaagct atgtattaat agtggaagat caaattgctg
    17041 gaacagctgc attagtctca ggcgtggatc ccgtttacac aaaaatagat ggtagttgga
    17101 aagaatcaac tggtccttat ttatcgattc atcgtgtcgc tttagcagaa agtactcgag
    17161 gaaaaaaact agcaaaaccg ttcttagaac atttgttgac gattgcagcc agcaaaaata
    17221 tccaagatat ccgtatcgat acttatccag ctaatgaacc gatggaaaag accatctatt
    17281 ctgctggatt cacttatcaa gggatgattg aatttccttt tgaacacggc gaaagaaaag
    17341 catatcaaat aatcatcaat tgactataaa atcatctgag caaagataaa gacattaaca
    17401 ctactgaaaa aaacaatcat atgatagcca agaggttgta acagaagtgg ccagcttcaa
    17461 aaaacaagaa agaatttccg aaaatgcttc tcaaattttt gtggaatttt agcgtatttt
    17521 acgaaatagc tgctttctga aactcccttc atcgagaggt cgtgacatag cttttgtcac
    17581 gatctctcgg cttatcctac gagtattatt cgatacattt atatcaataa tccttttttt
    17641 attttatctg cagcttcttg gaacgctcca tcgtttgaca cgactaaaag tgaggggata
    17701 gctttcaaac gtttcaactg tgctaaatct tctacataaa ccgccagtct ggctgaaatc
    17761 tgttcagatg aatctccacg ttttttcagg cgcgattgca atgtttcttt agagatcgta
    17821 ataaagatag gacggactac cgtcccgaaa tactcatata aatgccaaaa accatttgct
    17881 gtcaaaacgg cgtaacaatt tcctactgtc agtttctttt taatttctgc tttactggaa
    17941 ccatatttat gttgagcata ttggtcccac tctgcaaact catttccctt gatcatctga
    18001 ttgaatgtat tgtcagaaac aaaataataa tcctcttgat ctttttcccc aggtcttggt
    18061 gatcgattcg tgtaagtaat gatcttttgt tccggctgaa aaatagcttc tgcgagtgaa
    18121 gtttttccag aaccagaagg accgataaat acatagcaat aattcattgt catttctcct
    18181 ttgatgattg aacaagtgaa aaagctttgg aaaatatttc caaagctttt aaaagtaact
    18241 ttgctttttt gtattttata ccagcaagcc agtcacaata gcacttaaaa agctgactaa
    18301 agtcgctgtt agcaaaattt tcaatccgtg ttttgcgaca agatttcctt tttcttcatt
    18361 taatcccttc atcgcaccag aaatgatccc gatagaagag aagttggcaa atgaaacgag
    18421 gaagacagat ataattgctg ttgtacgctc agtaaaatgg aaattaccat ttgctaattc
    18481 tgtcatagca acaaattcat ttgtaaccag tttagtcgcc atgatactac cggcatccac
    18541 tgcttctttc catgggattc cgctgatgaa ggcaagaggg gcaaagatgt aacctaggat
    18601 ctcttggaaa gtgatgccga atatcccgtg gaagatagca ttgatcatgg caatcaaagc
    18661 aacaaaaccg ataagcatag cagcaaccgt gatcgccaca tggaaaccat caagaatgta
    18721 ttctcccaac atttggaaaa atgtctgttc tttgttttct tcaatgatca gctcatcttc
    18781 tttttcttct aatacatagg gatttacaat tgaagccaga atataaccgc caaataagtt
    18841 caaaacaagg gcagtgatca catatttaga atcgatcagt gccatataag atccgacgat
    18901 cgacatagaa actgtagaca tagccgatac actcatggtg aacaaacgtt tctcagatag
    18961 gaagggtaat tcctttttta tggaaataaa aacttccgat tgtcctaaaa tagcagaagc
    19021 tactccatta taagattcca atttgcccat cccgttgatt ttacttaatc ctagaccaac
    19081 agctttcata aataatggaa gaatcttgat atagcgtaga ataccgataa tagcagaaat
    19141 aaatacaatt ggcatcaata cggaaagaaa gaaaggtgca cttcctttat ttgctacacc
    19201 ggcaaaaaca aagtcaacac cttgcccagc aaaagcaaga agatgatcaa acatttttgc
    19261 caatacagaa acaaccgctg taccaaaagt tgtacgtaat aatacgaaac caagaacaag
    19321 ctgtaaaacg aacatcacaa ttagtggttt caatttgatt gcttttttgt tactgctgat
    19381 caaaaaagca agccctaatg tgacaaataa accaataata cctaataaat aactcaaata
    19441 atcactccta ttccaaattc cgttttattt tacctgtttt gcaaataaaa tactaatctt
    19501 tagtgaaatt ttcattactt ttttagagtg aaacgcattc attttccatt agaaaataaa
    19561 gcgaacaaaa taaaaggttt aaaaagtgta acgtcttagt aaagtctata aaaaaacgaa
    19621 actatcgatt aagctaatag tttcgttttc aacatttata agtaaacttt ttctattggt
    19681 aatatagatt ttcggaaggg tagacaggtg cgcaggtaat atcgattcct agttttttca
    19741 atgtttgttc atcattttta ttgaccatca cagtagagtg ggcttgtgct ccctcaagtt
    19801 cagctagttt atcataagca acttgagcga ttggattcgt tactgcactg attgataaag
    19861 cgatcaagac ttcattgatg cttagtgcat ccaaagagga atgaagtgtc tttgatttca
    19921 atccttgtat tgtttcaaga actaatggtg acaataaagg aatgtcatct gcgatatggg
    19981 ctaaatgttt tactgcattt aagataactg ccgctgacgc atccatcaat gaacttgtac
    20041 gcccggtaat gatgacttca tctggtaatt cgattgcaat cacagcagaa ggatcttttg
    20101 taggactttg cgcttgaatc ttatctgcat agtcatgggc agggactacc acgtttcggt
    20161 cttcaggacg taaaccgact tcttccataa tcagtttgat tcgattaact gcttcttcgt
    20221 cgatcaatcc ttttttgaag tcgcattctg tttggaaata acgacggatg atttcttgtt
    20281 tagaggcttc ttggacaacg gtatcatcca cgatcccaaa tcctacacga ttcacaccca
    20341 tgtcagtagg agattgataa acagattctt taccagtaat tttttcaata atacgtttga
    20401 ttacaggaaa tgtctcaaca tcccgattat agttcacagc tactttattg taggcatcaa
    20461 agtggaagga atcgatcata ttgacatctt ttagatcgac tgtggctgct tcataagcaa
    20521 tgttcagcgg atgtttcaac ggaacattcc atactgggaa agtttcgaac ttggagtaac
    20581 cagctgcatg tcctttttgg ctttcatgat acagttggtt caagcaagta gcgagctttc
    20641 cacttcctgg gccaggagct gtcactacaa cgattggttt agttgtttca atatactcat
    20701 tttttccaaa accatcttct gagacgattt tttctacgtt gactggatag tcttcgattt
    20761 ctgagtgttt atagaccttg atgtttcgtc tttctagttt attgataaag actttcgtgg
    20821 caggctgtcc actatagcga gtgataacga cactgttgat taataagcca taaccacgta
    20881 attcatcgat taaccgcaag atatccatat cataagtaat cccataatca ccacggatct
    20941 tattacgttc aatatctcca gcatagacgc aaatcagtat ttcagcttga tctttcaatt
    21001 tttgcagcaa tttgattttc gcatcttctt caaatcctgg aagtacacgt ttcgcatgct
    21061 tgtcgtcaac taacttccca ccaaattcta aatataattt gtcatagtgg ttcactcgtt
    21121 ccaaaatata cgctgactgc tcttcaatat atttttctga atcaaaacca atttttttca
    21181 ctaggttccc tccttaagta ctaaagcatt ttttcatttt tttgaggatt cgtcaactgg
    21241 aagagcgaaa ttcctcaaaa aaacaaagaa aatggtttaa accaacttgt ctagatagtt
    21301 attcattggt atgatagttt ttgataagga aggtgctaca tgaaaaaaag acagaaaaag
    21361 aaaaacgcat ataaacacta tatccgttcg atttttaccg gttatgaaag aatgcttgaa
    21421 gatcccgaat tggaacaatt gacgtttact tatctaaacg aagaaacgca gctaactcgt
    21481 gatgagcatc agcgcattca tttcacaaca agagatctgc ctagtaaata aaaaataaga
    21541 taaaggtcat cggattcgat tctgtcctat cagatggaaa gactagttga tcgaaaaaaa
    21601 ggctgtacca aattttggtg cagcctgttt tatggagcat tgcccgctct tttttataac
    21661 aattttttac agaaaatggt actattgaag tattaataag tgaaaaacag atgagtaaga
    21721 ggaggcaagt agtatgaaag agccagatac aaatgcaaat tatgagccag acgaactaga
    21781 ggagacgaac gcggatcagg atacaggaca agaatcgtct tctttttacg atatcaaaga
    21841 aaaagcaagc atgaatcttt cccaattatt agaagactta caggcttttg aaaaagctgt
    21901 ccgcgaagaa gatatccctg agatctaccg tttatacaat ggccgattga atgaagaatt
    21961 aaaaagaagc tcaaatgaaa atcacgagat cgatcaattg ctgatgcgta agatccatga
    22021 tcgtttttta caggaatttc cttttatgga acaagtagaa aacatctcgc caacgatgag
    22081 ctattacaaa atcggcactt attaccatga tcggcccacg gtcggtattg atgcaagtct
    22141 gccagaaatt tttgttttgc ctaagatcga tgaagagtgg gagaaatatt cccaaccgga
    22201 gtcaacggac tatgacaaaa aaatcaatga gctagacgca aaggtgatca ctgctcagac
    22261 agaaattgaa cgtttagatg aacaaataaa agaaatcaat cgacaaatga ctgatttgaa
    22321 cgacaataaa ggattcttga atcgtaaaaa aatcgaggaa gaaattcaag aattagagaa
    22381 gaagaagcaa gtactatcta atgaaaaatt aggctggctt ccttatattg agacgcctga
    22441 aacaatccag cagcaaaaag aagcattgaa gcaagaagca agagcagacc agcttcgtgc
    22501 agccatcgta gaaaaagaac aaaggcaaat cagacgctat ttcggtagca aagagggatt
    22561 cggtcaagca atccatgaat tcttgatgaa ttatcttggc aatgagaatc ctaataatca
    22621 atctaatgaa ggaggttccg agtatgaatg aacacgatga agcagaatgg acaaaaaatg
    22681 aagaacaaac agaagatcat gaagaaacga acacttcatt ggaagaacaa acaagtaatc
    22741 ctctggatga cacagaagaa atccctatgc tagaggaaac aaaaatacat gaaaaagaaa
    22801 aagtaactcc gacgaatacg aatactgcag aaaacaccca tgcttacgaa ataactgaaa
    22861 atcccgggta tttagaagga aaagagcaag atcatcaaga tatcgtcagt ttgattgaaa
    22921 cagcggaagc agaattagcg gatttacgta tgagaaaaga tttgatcgaa tcagattttc
    22981 cacaattatt agaatcatat gatcgtttta tattgaatga agaaccaatc tccacgatcg
    23041 gaaagacaag cctgatcgaa tacttcacgt atgaattact gaaaccgttg aatgatattg
    23101 gtctggaacg gtcaaattca gcttatgaca catggaaaac aagacatttt tcgatcaatt
    23161 atacgttgaa tggacaaaac gaattagtct tttcctttgt attaccgacc atcgatcaac
    23221 gataccaagt ggaatcgatg agtctcctaa acgtatcacc agagacaatg gaaatcaatg
    23281 tccaagatga ccgggtgctt tctttgatcc gacactggtc agtggatcga gtattctctg
    23341 cagggcagat cacgatattc aatcacaaat tgaatcaatt attagcccat gcaagaacac
    23401 ttggttttac cgttaatcag acattactag acaatacgaa gccacttcgt ttgaatcttc
    23461 agagcgaatt tgaattgacg aatgaagtat tggatgatat ttttatcgtg gcaatgaaaa
    23521 atccatccta cgatatggaa aagatcaacg aaactactta tcaagtacga ttagataaag
    23581 gacagtcttt aacgataaca acaaacgaaa aagatcaaac agtcttgtcg atctcatctg
    23641 gagactaccc acgatctgtc attgatttct ttatcaatta cgaattcttg gtcccattaa
    23701 tggtgagaaa gtcctgattg gataagttgg attaccagat gtcattcaga taattctgtt
    23761 ccaaaggact tgcggcagtt atccagaata attgtcacaa gtcttttctg tatgtactaa
    23821 atggacgtga ataacttgct gatgaaggag ggatttcatt aggaatgtcc acaaataaaa
    23881 tagcacagct tagcttattg tctgctgctt gtgtagcagg taggatcgct tttcaattta
    23941 ttccgaattt ccagccaatg actgctattt ttttatttat agtactttac ttaagcttaa
    24001 aagatgcgtt aattgtcatg agtctttcta ttgcgatcag cagtttttat tttggtgttg
    24061 gaccatgggt catcggccaa tggatcagct atactgttgt tctgagtttg ttttcaatcg
    24121 tctgcttgag aaaaacagtg caaaggaatc tatggttaaa gggagtctgt ttttttctgg
    24181 cgggcatggt ttacggaata ggtatgaccg tttttgatac gctgttatat cgtttgcctc
    24241 aaccttggat ctattacctt caaggggtgt cgtttgattt gatgcacagt ataggcaatg
    24301 ttgtgttctt tcttgttttt ctgccagtcg tcaaacgttt ttacaatcat tcaggaggaa
    24361 aaaatgaaaa aaataattta tagtttgctt gcaatgagtg tcagtatact cattttgaca
    24421 agttgcagta caacctatac acaatcggct tccaaccaaa aggaggaagt aaaaacatcg
    24481 caaaaagcaa caatcacgtt acaagaaaat ggtcaaaact tttcggaaaa agaagtggtc
    24541 ttcaaaaaag gcgatgattt actgagtatt ttgaaacgaa attttgaagt caaagaagat
    24601 aacggcttca tcacttcgct tgaagggcac tcacaggatg agaaaaatca actctattgg
    24661 atgtttactg tggacgggaa aagtgctact actggtgcca aagagatcaa attgaatgat
    24721 ggacaatcgg tcattttcaa tttgtctaaa ctataagttt cataaaaaac tgttaaaggg
    24781 cgaatattgc cataattcag tgagttcagt tgatgaaaga aggaaaataa catggaaaat
    24841 tttaaaaaaa gcggaatgtt ttccgtaatt gctgctctag gggctaatat tctagttgct
    24901 atcagcaaat ttgtcggcta tgcaatcagt ggcagtgccg ccatgctaaa cgaaagcatc
    24961 cacagtatcg ttgattgcag caatcagatt ttgctgttat tcggtgataa acaagccaat
    25021 aaaggacaga gcgagttgca tcaatttggt gaaggacgag caaaatactt tttcagtaca
    25081 atcgtcgcaa tgatgctttt cttcggcggt ggggcacttg gggtgatgga agcttttgaa
    25141 aagttgacgc atccatccca tgaagtgggt aatccgatca ttgttatagc aatactgtta
    25201 tttggtttgg taatcgaagg aagttcgtta cgcgtggcaa tgaaagaaat caaagaattg
    25261 aatactgaaa aactttccac gatgcgcttt ttgcgcgaaa gtcgacacag tgaaatactg
    25321 attattttta cggaagactt gtgtgctgta atcggtttgg tcttggcttt agcaggaaca
    25381 atattgactt atgcaaccgg gattgctgca tttgatgcga tcagcggatt gctgatcggt
    25441 ttcttgctga tgggagccgc cattttccta gcaaaagaat tttatagtct gatcatcggt
    25501 gaaagcgtga cagcaagcga tttatcaaaa atcaagttag cttttgaacg tcctgagatc
    25561 agtcggctga tcgatataaa aacagttcat ttaagtccaa cggagatttt agttgcagca
    25621 aaagcagata tcgttggtaa caaagagaat gaagcttact cggtcatcaa tgatattgaa
    25681 aaaaatatgc gtcagtctct tcctgacaag aagatgtata tatacattga aacagataaa
    25741 tatgacccaa attattctcg taaataaaac gtttattcat gaattgaagc aaaaatgaga
    25801 aaaatataat cttgttttta aataaaacgg ctacaattta gcgaatttat gttacaatga
    25861 gtccgctgtt tatttgttgt aattaaagga gatattttaa tgaacaaaaa gaaaagtgcg
    25921 ccatggcttc aagctttgca tgcagtgatg ccactttgta taagctatat accagtagga
    25981 ttagcttgcg gagtattgtt gcaaaaagtt ggatttgatc ctctcttatc aggactgtta
    26041 tcgattctgg tcttttccgg tggcgcgcag tttttagttg catctatgct tacgacgcaa
    26101 gcatcatttg caacgacatt attgatggtt ttctttttag aattacgcta tacattatta
    26161 ggagcaagtc ttgccggttt tatgaaaaaa gaaaagcgga cgtttttggc tgtcttttct
    26221 caatcactga atgatgaaaa ctatgcggtg aactacttaa agttttcaac tgacccttcc
    26281 tggaataaaa gaaaggcttt atatgtcaat tggttctcaa tgactgcatg ggccggtagc
    26341 aatatgatcg gtaatttttt cggctcggtg attcgagtag atgctgacct tgtccatttt
    26401 gctttgacgg ccatgttcat tttcatgttt atcatgcaga tgaaaagcgc actactgatc
    26461 tttacaggtt tattctcagg cgtattaggg gtcgtattca tggtattttt ccaaaatact
    26521 ttcggattga ttgcagcaac agtcattgct tcatttgccg gatttatgct ggagaaggca
    26581 ttcaaaaaag aaaaagctaa gaaactaaga gaccgcggta aagatgtcaa tgagccgctc
    26641 ttcaacttcc cggaacagga ggccaatcac catgactaaa ctatatttgc tacttttagt
    26701 tgcttgtctg ttcatcgtgg catatatccc gcgcttgttc ccgatgcttt attttactca
    26761 tcgaaaagtg ccatcctggt tcagtgactg gatgaaatat gtaccggtgg cattatttgc
    26821 ggcgttagct tttaaagatg ttttcattac tcatgaacat ctggatattg cttggaatat
    26881 caaaatagct gcaatgattc tagtagcagg cgtggcttac aaaacacgtt cgatggcgtt
    26941 gtcagttttg acaggacttg cgtctgtctt tttgctgtct atgctttaaa ctgttttatt
    27001 ttattaaaaa cagagattgc gacataagtt gttcaaactg atctatccga actgcatttg
    27061 caacagtcaa ttctggatgc aagtttattc gtagggataa aaaagattag tgttggctta
    27121 tgatgcaagc tcttttttat tttaggaatt agagagggat ttgtccttct atgatttttt
    27181 gctataatag ggaagatgtt tattttatga aagaatagtt gagggaattt aaatgaataa
    27241 aaaattgatg caaggaacat tttggctaac ctttgctaat cttctatgta aagttttagg
    27301 ggtagtctat ttgattccct ggctaagtat gatggggaac aatcaagatg gtatgcttgc
    27361 tacgacattg tataatgttg gctatcttcc ttatggattg ttcctgatgc ttggtacagt
    27421 cggatttcca aatgcgattg caaaaaaagt agctgtagcc acaaaagaag gagataacgc
    27481 tgcttgtcgg ctgattttta gaagtacgat caatatcatg tttgtcatcg gtatcgcctc
    27541 tgctgcactg atgtatttat ttgctccttt actagccgga atcagtccga ttgctaacgt
    27601 taataatggg atactagcta tcagaagttt atgcccatct ttgattgcta tcccaattct
    27661 tagtgcaatg agaggatatt tccaaggaaa aaatgatctg cggccttatg gaacttcttt
    27721 gattatcgaa caggctgtgc gagtgatcgt tatcttggct ggtacttatt acttgcgcgt
    27781 attgactgac ggaaccatat tagaagctgt attgatcagt acagtcgctt ctttcttcgg
    27841 tgggttagct gcgattatcc atatgtatat cgtcggacgc agaaaagact tcttcgaact
    27901 taaagatttt ttgatttcca gccgttattt cgaaagagaa aaccgatctg cctctgtctc
    27961 tatcattcgg gaaacactac cgtttatttt tgtcggctca gtcattacta tcgttcaaat
    28021 gatcgaccaa gtaacgatga aaccactgct tcactttttc cgtccagaga tcgcagatca
    28081 gcaactggaa ttcttattca gccgtgcttc tgtcaatcca aataaattga cattgatcct
    28141 gatctccatg gtaggaacag tagctataag cagcttgcca atattaagca cgatgaagaa
    28201 aaaagatcgg atacaaatcg aaaaaacagt aggagatagt ttttcgattg cgttattgat
    28261 tcttcttcct tcattgactg gaatgtcttt attagctgga ccactataca cattgttttt
    28321 tggctatgat cctgaaagtg tcggatattt ccaaatggct ttgctagctt ctttgttttt
    28381 ctctttattc acgatcctat ctacgatgct tcaatctttg aatcaccatc gttttgcgat
    28441 ccgattaact gtagaagcaa ttatcctgaa agtcatcttc caagtaatcg gattaggatt
    28501 agttggcgga tacgggatga gcttatcaaa tggcttagca ttcggtattg tctttgttcg
    28561 cggctatcac tttatgtgca aagaataccg aatagcacct ttagcaaaga tcagcaattt
    28621 tttcttaaaa actttccgct ccaccctgat tatgcttgca gtatgttttg ccgttttctt
    28681 tttgctgaat cagcgattgt caatggaatc aaaaagctat gcaatgattt attgtgtggc
    28741 tgtaggaagt attggcggct tagtattttt attttctcaa ttcggaaaaa atgggtttcg
    28801 aatgttgaaa aatgttaaac atcatagcag aagcaaagaa taggttaact aatcgttttt
    28861 tgctgtcact tgaaaaacgg caactcgtat gattacgctt gtcgtttttc tattttccaa
    28921 ttttagtttc atatctaatc ttacttatga tatagttata aggtctggaa aaattctttg
    28981 aaacgaggaa attaaacaca tgaaacttgc agtagttaca gatagttcgg catatctgcc
    29041 ggaacgtatc aagaaccatc ccgacttatt cgttattcca atccctttga ttatggatgg
    29101 gaaaatttat aacgaaggaa tcgatatcga agcggatgaa tattatggac ttttaaaaaa
    29161 cagtaaagat tttcctacta cttcacaacc tgtcgtaggg gaagttttgg gtttatatga
    29221 ggaattgaaa gagaaagggt atgacacgat tttaagtatc catctttctt cagggatttc
    29281 tggctttgtc aacacattat ttgcgatgaa agatgacatc agcggagtaa cggtcattcc
    29341 ttatgactct aagatcacta gtatgccgat gggacacatg gtagaagctg ccttagactt
    29401 aaatgatgaa ggtcagtccc ttgatgaaat acttgcacat atcgatcgaa tccgagataa
    29461 tacctatgct tatctgattg tagatgattt gaacaattta gtacgaggag gacgtttgac
    29521 aaatggtgca gcgctgattg gcagcttatt aaaaatcaaa ccgatcctga cattttctga
    29581 agggaaaatt gttttattcg aaaaaatccg ttcaagtaaa aaagcatttg ctcgagctga
    29641 agaaattatt ggtagaagaa ataacgaaat acaaccgcca gtcaaacttt acgtgataca
    29701 tgcaaataat ttagaagtag cgattgcgga gaaagagaaa ttgcagaaaa aatatccaaa
    29761 tgcagaaatc gaaattggtc atttcggacc agtcattggt acacatttag gtgaaaaagc
    29821 catcggcatt gccatttcag cgcaataatt ccttttattc aaaaaacata ccaaaaata
//
LOCUS       DAXLPQ010000030        29625 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.030, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000030 DAXLPQ010000000
VERSION     DAXLPQ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.030"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(34..477)
                     /locus_tag="ACF3UO_001615"
     CDS             complement(34..477)
                     /locus_tag="ACF3UO_001615"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3657646.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(493..1653)
                     /locus_tag="ACF3UO_001616"
     CDS             complement(493..1653)
                     /locus_tag="ACF3UO_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3657647.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTIAEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            2529..4229
                     /locus_tag="ACF3UO_001617"
     CDS             2529..4229
                     /locus_tag="ACF3UO_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657648.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNIRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFNKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKHLRA
                     "
     gene            complement(4331..5164)
                     /locus_tag="ACF3UO_001618"
     CDS             complement(4331..5164)
                     /locus_tag="ACF3UO_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFD3657649.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLAKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEEGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(5714..7879)
                     /locus_tag="ACF3UO_001619"
     CDS             complement(5714..7879)
                     /locus_tag="ACF3UO_001619"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFD3657650.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNRQADS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLEVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            8139..10433
                     /locus_tag="ACF3UO_001620"
     CDS             8139..10433
                     /locus_tag="ACF3UO_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFD3657651.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFAGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEATITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            10426..11091
                     /gene="pgmB"
                     /locus_tag="ACF3UO_001621"
     CDS             10426..11091
                     /gene="pgmB"
                     /locus_tag="ACF3UO_001621"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFD3657652.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDRTFNEQLK
                     GVSREDSLSLLLAHGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            11084..12091
                     /locus_tag="ACF3UO_001622"
     CDS             11084..12091
                     /locus_tag="ACF3UO_001622"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3657653.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEELPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRKMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            12113..13132
                     /locus_tag="ACF3UO_001623"
     CDS             12113..13132
                     /locus_tag="ACF3UO_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657654.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(13413..14780)
                     /gene="nhaC"
                     /locus_tag="ACF3UO_001624"
     CDS             complement(13413..14780)
                     /gene="nhaC"
                     /locus_tag="ACF3UO_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFD3657655.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(14889..16310)
                     /gene="tyrP"
                     /locus_tag="ACF3UO_001625"
     CDS             complement(14889..16310)
                     /gene="tyrP"
                     /locus_tag="ACF3UO_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFD3657656.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(16553..18430)
                     /gene="tdc"
                     /locus_tag="ACF3UO_001626"
     CDS             complement(16553..18430)
                     /gene="tdc"
                     /locus_tag="ACF3UO_001626"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFD3657657.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FTDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(18721..19977)
                     /gene="tyrS"
                     /locus_tag="ACF3UO_001627"
     CDS             complement(18721..19977)
                     /gene="tyrS"
                     /locus_tag="ACF3UO_001627"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFD3657658.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(20089..20294)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20557..21858
                     /locus_tag="ACF3UO_001628"
     CDS             20557..21858
                     /locus_tag="ACF3UO_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3657659.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(21927..22526)
                     /locus_tag="ACF3UO_001629"
     CDS             complement(21927..22526)
                     /locus_tag="ACF3UO_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3657660.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            22780..23661
                     /locus_tag="ACF3UO_001630"
                     /pseudo
     CDS             22780..23661
                     /locus_tag="ACF3UO_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23674..25284
                     /locus_tag="ACF3UO_001631"
     CDS             23674..25284
                     /locus_tag="ACF3UO_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657661.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(25361..26020)
                     /locus_tag="ACF3UO_001632"
     CDS             complement(25361..26020)
                     /locus_tag="ACF3UO_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3657662.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(26303..26968)
                     /locus_tag="ACF3UO_001633"
     CDS             complement(26303..26968)
                     /locus_tag="ACF3UO_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFD3657663.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(27115..27720)
                     /gene="dhaL"
                     /locus_tag="ACF3UO_001634"
     CDS             complement(27115..27720)
                     /gene="dhaL"
                     /locus_tag="ACF3UO_001634"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFD3657664.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(27748..28758)
                     /gene="dhaK"
                     /locus_tag="ACF3UO_001635"
     CDS             complement(27748..28758)
                     /gene="dhaK"
                     /locus_tag="ACF3UO_001635"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFD3657665.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(28733..29128)
                     /gene="dhaM"
                     /locus_tag="ACF3UO_001636"
     CDS             complement(28733..29128)
                     /gene="dhaM"
                     /locus_tag="ACF3UO_001636"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFD3657666.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            29282..29602
                     /locus_tag="ACF3UO_001637"
     CDS             29282..29602
                     /locus_tag="ACF3UO_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFD3657667.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
BASE COUNT         8701 a         6151 c         5399 g         9374 t
ORIGIN      
        1 taggctggga gcattatttc gttattctgt tcatcaaaaa tcagcgtttt gattccattt
       61 catcacaagt tcctcctcat ttactgcttc atctttttgc tgtgtttgaa ttgtaaaacc
      121 ttgtgaaaga tagaaatgaa tagctgattg atttttttga tagactgtca aagtcagtgt
      181 tttattggtt tcttttattt ttttcattag ttgcgtaccg attctttgtt gccggtattc
      241 ccttttcaca aagattcctg cgataaactg atcaatcacc ccagcaaaac caataatttc
      301 ttgatctatt tctgctaagt aaatcactgc atctggtaaa gctttcctaa cagattctac
      361 ttgattctcc caataagttg atggaatgaa ttcatgagaa tccaagttag catgtagcca
      421 aatcgataga acagattcca gttctttggc agacaatttt gttgttgtgc ggatcatttt
      481 ttctctcctt acttattcat tgattttaaa ataaaaacca tttttttgaa gctcttttac
      541 aagttttcgc ccctcaaaaa agtatatctt ctcttgtttt acttttctaa taccaaaaga
      601 aacagcaact ttaggatcat cagctgaaac gattcgataa gtcccaccag gcaattgatc
      661 cagcttgact ttcccatgat ggtcgctttg tactgaaaac ggcacaccat ttctagtaag
      721 tgtttttttc ttatgtttca aaatgaatga actaccattt accggtttcc ctgacgaatc
      781 actaataata aatgaaaaat caagcacttt tttacttaat ctatactgat agattagtcg
      841 tccgataaac actaacagta tgactacagc tattatcgtt cctgcaagaa taaaccattg
      901 ccgcatggtt ctttcctgat ttccttttcc ttcttctttt tttaccgatt cgttataagg
      961 aatccgatgt cctgtcacta gcaaacgatg cgtgttgatc atatacggcg tacatgtaag
     1021 caaggtaact aagtcttctc cttctgcaat cgttagaaca gacgtgtcat ctggcagtac
     1081 cacttgtata tttttaactt gataagccaa tttctctccc aaaacagtca aaataaacgt
     1141 gtctccgttt tctaaacgat ctaattcggt aaataaccgt cgattaggta aaccgctgtg
     1201 agcagagatc actgaatgcg tcgaatttcc accaagcggg aaagaggttc cttgcaagac
     1261 gcctgctcca ttttcaagga tcctaccatt gagccgatca taaagtgaaa tatttaattg
     1321 gatcttaggt atattgatac ttccgatcag ccattcctct aattggctgg atgttgtact
     1381 ttcatttctg ttcttttcat tgaaaggatc agtaccagga ttgaatcctt ggtcagttaa
     1441 tcgttggttt ttctcctcca ttttctttcg ctgcacttca atttcagctg cggtccgttt
     1501 ttgtacttgt tcgatacgtt tttgatcaat aaaactattt aaagaatcca cataaaatgg
     1561 atataaagcg atcagtaacc ctacgacgat acatattaat aaaaacaaac gaaacaaaag
     1621 tcgacgagac tgtttttgct tactctgctt cacatgtgtc ctcccttgca agtttttttg
     1681 ttctttcttt tattatatgg gttcaggaaa aaaatagaaa atgaaagccg atgagattgt
     1741 gaaaaagctg tcctgcatca agtaataagt acagcctcaa aaaatagcta ctcatatttt
     1801 ttgttgggtt gggcttatta ccgcagatgc aagcttttga acaccgttta aggaagaggt
     1861 tgtgaaaact gcgttatgct ttgagtaata agagtgctag tcagaaaata gcttctcata
     1921 ttttctaggc tagtgagctt attaccgaga agcagctgat tgaacaccat ttaaggaaga
     1981 ggttgtgaaa actgtgttat gttttgagta ataagagcgc tagtcagaaa atagcttttt
     2041 atattttcta ggctagtgag cttattaccg agaagcagct gattgaacac cgtttaagga
     2101 agaggttgtg aaaactgtgt tatgttttga gtaataagag cgctagtcag aaaatagctt
     2161 tttatatttt ctaggctagt gagcttatta ccgagaagca gctgattgaa caccgtttaa
     2221 ggaagaggtt gtgaaaactg cgttatgttt tgagtaataa gagcgctagt cagaaaatag
     2281 cttttcatat tttctaggct agtgagctta ttaccgagaa gcagctgatt gaacaccgtt
     2341 taccgagagg tcatgaaaaa gctactttgt ttcgagtatt aagaaaaatt ctgtttcaaa
     2401 acaaggagat gcaacaaaac ttatgtcgca tcctctctcc ttagaacttt cacttatgtt
     2461 tttcttgtaa aattcataaa tattttcatg aattttctaa tttcttgcct acctctcgca
     2521 taggatatat gatgaattta tctaaagttt gcaaaggagt tcgacaattg aaaaaatatg
     2581 gcccattttt agcaattttt ttcattgctt tggcatttct catgcctcat ttattcacac
     2641 ataaactaat tttgggtgct gatgccccat tccattacaa tcggttctat gatgccgcgc
     2701 aacaaattaa atatggggat ttccattatt ttccttccct ttatggattc cagcaaagtg
     2761 gcaggatcgt gaatgccgtt tacggcccat ttttcgctta tttacaagga ttgatcgtgt
     2821 tgcttgcagg tagctggttt cattatcaga ttctttcaaa tttcattctt tatcttattt
     2881 caggattttc tatgctgatt ttactgagat atgtcaatat tcgaaattgg gtaagtgtac
     2941 cagtagccgt tttattcatg agtacgtatt ctattcaata ctggtctatc aaccaaggat
     3001 tcactagctg ggggacttgt ttttatcctt tatgtatgat ccctattgct gatttcgtcc
     3061 ttcataaaaa gtttcctgtt atcaaagtcg ctgtctcagt gggacttatg acacagatcc
     3121 atttactgtc ttcgatcatg ttagctttga tgtatattcc tttttatctt tattactttt
     3181 ttaaccagac tgaaaaagga aaagcactgc ttcaactgat taagtcggtc ttgctttatt
     3241 ttgttctgac agcaaatatt tgggcaggat tagctattgt ttacagtggg aataagattc
     3301 ttcctccctt tgttaacaga gaaatgagtc aaaaggcgat agatctggat ggcagttatt
     3361 ggctccatta ccctaaggcc tttcctatat tgatattatc aggttttttg ctttttattt
     3421 tctttcaaca aaagaacacc ttattccaaa aaatcgtgtt gtacacaagt cttgttttct
     3481 tttttctttc tactagcttg attccatgga cgacattgat cgaaaaaaat gtgcctttta
     3541 ttagtttgat ccagtttcca tttcgatttt tcgtgccatt tacgctattg cttctacttt
     3601 accttgccct ttcactgaac cagtggtctg aacaaaagtg gttccgtctt ttaagtatat
     3661 ttggcattct tattttttca gcacagacga tccagaactt ataccagcat ctggaaaagt
     3721 gggaaaatga aacatttgtc agtcgacata cttatctatt cgatacgccg gaagaagcaa
     3781 ggaaaacatt cttcaacaaa gatatgtcta ccagcttgtt cgttttccaa aaaaccacac
     3841 ctgactatct gccaatctat aaggagacaa aagacaataa atacgaccgg tataacgaag
     3901 aaatactaga aaacgaaaca acttttataa aaacacatcc aggcggtctt ctgacaatca
     3961 agtggaaaaa cactggggac aaaactgttc atatccctgt tatcgtctac gatcggactg
     4021 tgctacagca aaatggaaaa acattgactg attatgaagt aacagatatc gggaccccaa
     4081 tcgtgaagca gcaaaaagga atcaacgagc tcacgcttca ttatcaaacg ccaatctatt
     4141 tctatttcat tctttctctt actttgattg gctggtttac cttgctatgt ttatttattt
     4201 atcatagata caagcattta cgtgcttagg caaaagggat aaatgcatcc gatcaaaaaa
     4261 ctctccaaac ggtataatcg tttggagagt tttattttaa tcagtttttt tatgttatat
     4321 gttatatttt ttattcgttc acatctaatt cgatttccac cccgtagtga tcactgatga
     4381 ttggactatc gatcccatca aaaatccgtt gatatttttt aacctgcatt ccttcaggga
     4441 cgaaaataaa atctatacgc aatttttctg tattttgttc ccaaccatcg attttctttt
     4501 ccacagtagc tgcttttcct tcttcattcg cgacaacata cgaatcttga agaagaaggc
     4561 aactttctct tacagtataa taaccttgag agtctactgg attattgaaa tcacctagga
     4621 aaaaaagtgg tacgcgagtt tccaaaaagt agttttccaa gtttttccac tcaaaataaa
     4681 agccactttt tttatctgtc caccaagaaa agtggcagct cgagacaaaa atgtcctgat
     4741 catctatctt tgttttccca atcaagatct tgcgtgtctg ataatcttct ttcttttgag
     4801 attgggagac ggtaaggacc tgactttcca atgttttttt cgcaagcagt gcatttcctt
     4861 cttcatattt atcataaccg atgtggctca tttcccaact ccaaaaatac tcttttccgt
     4921 gttcctttaa aagctgaact aaacggtagg caaaattatc tttacggata ggtacttgat
     4981 tctttaccgg acagaacttc attagcttcg caggttctac ttcttcagat tccagtaatt
     5041 ggttgatttc ttgtaaagca atcacttcat aatcttctaa caggatctta tctgctaatt
     5101 cttgcaattt tttctctggt tctggctcaa gccagctatg cgtgttgagt gtcatgaatt
     5161 tcattggttt tctccttgtc ttcatttcga aacaaaaggg ttgtgacaaa atttttgtca
     5221 caacctctcc agcaaatagt gttctcctgc taactcctca gtaataagct caatggacca
     5281 ggagctattt tttgtttggc tgtttttatc acttggtgca gggcagcttt ttcacgacct
     5341 ctccactaaa cagtattcaa actgctgctt ctcggtaata agctcactag cctagaaaat
     5401 atgaaaagct attttctgac tagcgctctt attactcaat gcataacgca gttttcacaa
     5461 cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     5521 aaataggagg agctattttt gtttggctgt tcttattact tgatgcagga cagctttttc
     5581 acaacctctc gataaatggt gttcaatcag ctgaccttag gtattagttc aaaaaacggc
     5641 aaaatacgag gagctgtttt ttcgttttgt ttctctaata ctcaggtcag gacaatgatt
     5701 tcacaacctc tccttacatt ttaatggagc cgatcacttt accagctgtc actgtaccta
     5761 attgcttgat cactacttct tctactttat cgtttgtaaa tacgatcatg atcgttggat
     5821 ctttttcttc attttggatc acctcaagat ccatctcagc taatttcgtt cctgttccta
     5881 cttcttggcc ttctttgaca gcaatctcaa aagctggctg attcatttgg actgtatcga
     5941 tacccatatg gatcaaaact tcgataccat ctttcgtctc cagcccaatt gcatgtttgc
     6001 ttgggaaaat acttgtcact tttccagcga tcggcgcaac aacttctctt gatgttggaa
     6061 taacagcaaa gccgtcaccc atcatttttt gtgagaatac cggatctttt acttcagata
     6121 aaggaatcac ttctccagaa gctgcggaaa ctagttcttg ttctatacct aagtattgct
     6181 tactatctgc ttgtctattt cctgtagaaa ccatttctgg ctctggaatc tctgctcctg
     6241 attgcagcag atcttcgata tctgatttca agacatctgc ttttggtcca taaactgctt
     6301 ggactccatt gtctttgacg atcaatccca tcgcccctgc tcgtttccag gcttcttcag
     6361 tccctacttt ttctcgatca tttacactta cgcgtaaccg agtcatacaa gcatcgacat
     6421 ctttgatatt ttcttttcct cccagcaaat gaatgatctg gaccacttgc tgatctgctg
     6481 ttcctgttcc gctgttagat acaacggttt cttcactgtc attgtcgtaa tttccgttac
     6541 gtcccggtgt agcaaagttg aattttttga tcaagaaatt tgctaagaaa tacgtaacaa
     6601 caccaaaagc gatcacacac aacacgaagt tgataagatc tccacctaaa cccgctttga
     6661 tagctaacgg tgtccgagtc agcaattcga tattcccaaa tgaatggacc cgcaatggca
     6721 agatatctgc catcgcaaat gcagcccctt ggatcactga ataaatgaca tataatggca
     6781 cagcagcaaa cataaacatg aactccaatg gttctgttac acctgttaga aagacagcca
     6841 acgctgctga aaaatacatt gatttatatc ttgctttctt atcaggatcg acattacgat
     6901 acatcgcaaa agccattccc atcaagatac ctgaagaacc aatcatttgt cctactttga
     6961 aacgagccgg cgtccagtta tgcaacacaa actcatattg cgacatatcc cctgcacctt
     7021 taagattcac taaatcagtg gcccaagcca accataacgg atcttgccca aatacttgtg
     7081 tccccgcctg tgcgcctgat aaaatctcat acgatccgcc aagctgtgta tagttgatag
     7141 gaatcgtcag catatgatgc aatccaaatg gcaatagtaa acgttctaat gttccaaata
     7201 aaaacggtgc tagaatcggt gcgctttctt gtgattctgc gatccataaa ccaaaattat
     7261 tgattccagc ctgtacgttt ggccacacca cagcaagaat caatgccacg attgttgacc
     7321 ataagataac aacaaacgga acaaagcgct ttccattgaa aaatgacaaa gcatccggca
     7381 attttctata attatagtac ttattataag ccattgcccc gacaaatcca gcgatgatcc
     7441 ctacgaatac tcccatattc aaagctggtg cttccaatac acttgtaaaa aatcctttaa
     7501 ccatgatctt cgtaccgaac agagtgtggg taaatgcatc ttcattcgca agcatgtcac
     7561 ttgtgacacc aaagatagcc ccagtgatcc gattgatcaa aataaatgag atcccagctg
     7621 caaatgctcc gcctgctctt tcttttgccc aacttcctcc tattgctaaa gcaaataaaa
     7681 tatgaagatt accaataatt gcccaaccaa tattttcaat tactccgcct gttgtgacaa
     7741 gcggcgtcca atcaggattg atcaagggaa ttgatttccc tatactgatc atcaacccag
     7801 ctgccggcat aactgctacc acaaccatta aagcctttcc aaatttttgc caaaactcaa
     7861 aactaaatat ctttttcatt ccgtttagct cctttacgca atcggtttcg ttaaacgtat
     7921 tatagcgtgc gttttctttt ttgtaaatgc tttatttttt atttttctgt ctataccatt
     7981 ctagaaaacc tataatgcgt gtgttccctt ctataatttt ctcctaaaaa tttatttttt
     8041 tatgcttttt tctatgaaat attttctttt gtctattgac ttgtgcaatc ggttgcgttt
     8101 attatgaacg tataaaacag ctcattagga ggagaaaaat gaaacagatc aaacgactat
     8161 ttgctattga tccatggaaa atcagcacga cacaattaga taaaaaaaat cttcgactgc
     8221 aagaatcttt aacaagtatt ggaaacggtt atatggggat gcgcgggaac tttgaagaaa
     8281 cttactcagg ggaccaccat caaggtactt atttggcggg tgtctggtat cccgataaga
     8341 cacgtgtcgg ctggtggaaa aatggttatc cagaatactt tggaaaagtg atcaacgcct
     8401 tgaactttat cgcgatagat atttcgatca acgatcagct gatcgacttg gcttctttgg
     8461 aaccagaaga cttttactgg gaattagata tgaaaaatgg tgtattatct cgtacattca
     8521 caatcactac ttctactaat aaagtacgca tttccttcga acgttttctg agcattgtca
     8581 aaaaagaatc agcttatatc tatttaacta tagaaatgct tgaaggtagc ggaacagtca
     8641 aactcgtatc aaaattggat ggaaatgttc aaaacgaaga cagcaactat gatgaacatt
     8701 tttggaatga gattgatcgt ggaactatag aagaaatcgg ctatttgacg actaaaacta
     8761 ttccaaacaa ctttgggatt gaacaattta ctgttactgc agcaatgcgc catttcgtta
     8821 atggaaaatc agtcatccct gactatcacg aagatacttt agcattacat ggttgcttgt
     8881 ctgcggaatt atctcaaggt gagacatggt cagtggaaaa agaaattatc gttcttacta
     8941 gtagagatat tccagaagcg cagcaagcag aaaaagctgt ctcagaatta acgaaccaga
     9001 caaacaatta tatccaagca aaagaagagc aaacagcggc ttgggcagaa cgatggaagc
     9061 ttgccgatgt ggtcatcgaa ggagacgaag aagcacaaca aggtattcga ttcaatttgt
     9121 tccaactatt ctctacttac tacggcgaag atgaacgatt gaatatcggc cccaaaggat
     9181 tcacaggaga aaaatacggc ggagccactt actgggatac agaagcgtat gctgtccctc
     9241 tttatcttgc tttagccaaa cctgaagtaa ctaagaatct gctgaaatat cggcataatc
     9301 aactgccgca agcaatccac aacgctcagc aacaaggatt aaaaggcgcg ctttatccta
     9361 tggtcacctt cgctggtgtc gaatgccata acgagtggga aatcacattc gaggagattc
     9421 accgaaatgg cgcgattgcc tatgcaatct acaattatac gaattacacc ggcgatacgg
     9481 aatatttgaa aaatgaagga ctggaagttt tagcagaaat agcacgcttc tgggcagacc
     9541 gtgtccattt ttcaaaacga gcaaataaat acatgatcca cggtgtgacc ggcccaaacg
     9601 aatatgagaa caatatcaat aacaattggt atacaaatac gatcgcagct tgggtcttgc
     9661 gttacacgcg agaaaattat ttaacttatc aaaaagaagc tactatcact atcagcgaag
     9721 aagaactagc caaatggaaa gatatcgcag agaacatgta cttcccagtt gacgaagaat
     9781 taggaatctt tgtccagcat gacacattct tagataaaga tctcatgcct gtatccgata
     9841 ttcccacaag cgatcttcct ctaaatcagc attggtcttg ggacaaaatc cttagatctt
     9901 gcttcatcaa gcaggcagac gtactacagg ggatttattt cttcaatgat acttttacaa
     9961 aagaagaaaa acaaaaaaac tttgatttct atgaaccaat gactgtccat gagtcttccc
    10021 tttcgccaag tatccattcg attttagcag cagaattagg aatggaaagc aaagctgtag
    10081 aaatgtacca gcgaacagct cgcttggatt tggataatta caataacgac acagaagacg
    10141 gcttgcacat cacttccatg actggtagct ggttgtcgat tgtccaagga tttgctcaaa
    10201 tgaaaactgc ccatgatcag ttgagattcg caccatttct gccaaaaact tggaaagctt
    10261 attctttcca tatcaattat cgcggacgtt tattgttcat ctcagtcaca gatgaacaag
    10321 ttactttcga gttattagaa ggttctcctc tagaaattta cgtctatgaa cagtcttatt
    10381 ctttagcgga tcgtctagaa ataacgctaa gaaaggagga agcaaatgtt taaaggggta
    10441 ttgtttgatt tagacggtgt cattaccgat actgctgaat tccattatcg tgcttggcga
    10501 aagcttggtc aggaaatcgg cattacgatc gatcgtacat tcaacgaaca gctaaaaggc
    10561 gtcagccgag aagactcact ctctttgctt ttagctcatg gcggaaaaga acactctttt
    10621 tcaaaggaag aatttgcaga attagcgaaa agaaaaaacg attattattt agagatgatc
    10681 cagacgatcg aaccaaaaga tgtcttcccc ggagtcgtgc ctttactaga ttctttaaaa
    10741 gaagaaaaaa tcaagattgc tcttgcttct gcaagtaaaa acgggccttt cctacttgaa
    10801 aaaatgggtc ttacacctta ctttgatgct attgccgacc cggcagaagc aacaaacgga
    10861 aaacctgcgc cagatatctt cctccttgca gcaaaagctg tcggactaaa agcagaagaa
    10921 tgtatcggga tcgaagacgc gcaagccggt atccaagcca tcctctcaag tggcgctcaa
    10981 ccaattggcg tgggacgtgc tgaagacctt ggagaggaga tcccgcttgt ccctgatacg
    11041 acttttctta cgatcgatta cttgaaagaa aagtggcatg accatggata atccagaaat
    11101 ctccgtcgta ccagttccag agactgaaat aaagaaaatc acattgaaga acgactactt
    11161 agaagtcgtt cttctcaatt acggtgcccg cctgcaccaa atcttcgcac cagacaaaga
    11221 aggaaaatca gaaaatgttt tattgtctta cgatcgtttc gaagatgttc taacagacaa
    11281 aagctttttt ggagcaactg tcggacctgt agccggaagg atccgggatg cttcttgggg
    11341 tgagcataga ttggagaaaa actgcggatc acaccatatc cacggtggca cgaaaggctg
    11401 gtctttccaa ttttgggaag tagaagtttt caaaactcca tcatcaatag gtgtggtctt
    11461 ttacttaaaa gatgaatttt ctacctatcc aggaccaatc actgctacga tcacttaccg
    11521 tttaacaaaa aacgaattag agatgacaac ctctgctagt agccttgttg aaaccatctg
    11581 caatccgacc aaccatgcct acttcaacct ttcaggaaat ggaacaagag acatctatga
    11641 acatcagtta acggtctttt tagatggtgt gcttgaatta gatcaagaaa aactgcctac
    11701 tggaaattgg acaaaaaaag aagaactgcc aatcgacttt agaaaatccc caacactgca
    11761 agagatcctt gcatgttatc cagatggact agatgatgta tttcttttgc atcatcctag
    11821 gctttccaaa acttccttac aattattcga gaagcattct ggtcgcaaaa tgactatagc
    11881 aacttctaat aaaagtatgg tattattttc tacgactgga ttcgaagctg atttctctgt
    11941 caatggaaaa cagatgcatt caaactacgg attagcaatc gaaccgcaag aaatccctga
    12001 tatcgttcat ttccccaaat ttggatcgat caacctccat cctggtcaag aacggatcag
    12061 tcagacgatt tatcggttct ctgcacaata acaagagaaa ggtgttttta tcatggctat
    12121 taccgtaaaa gatgtggcga aaaaagccgg tgttgccacc tcgaccgtct ctcgtgtcat
    12181 caacgatcat cctagtattt ccgagacaac aaagaagaaa gtccgaaaaa ttatggatga
    12241 actaggttat gttcctaaca tgactgcccg caatctagga aaacgcattt ccagtgccat
    12301 cggcgtaatc ttaccccctc ttgattcaaa agagcggatc ggtaacccat tttatcttga
    12361 gatcatggaa gcaatcaacg aagaagcgcg gaattatgat atgactacag caatcgctac
    12421 tgctaaaaat tttgaattgc tgttagagaa cgtccagcgt atgcatttac aaaaacaagt
    12481 agatggtttt attctagtgt attcagatag tcaagatcct gtcattgatt atttatacca
    12541 aaaccacatc cctttcactt tgatcggaca gccttatcat catgagaacg aaatcgttta
    12601 tgtagataat gataaccagc ttctaggtaa acaagcaaca gaatttttga tccagaatgg
    12661 acataagaat atcctgtttg tgacaaacac gactcatgaa agtttgtatt tcgaacgata
    12721 tttcggttat caaaaagcaa tgatgatggc tggtcttcct gcgttatcca gtgtagtact
    12781 agagcatccg gaagattatc tgtcctttga gaaaacgttg aaagaaaacg aagccacagc
    12841 attggtggtc attgacgata tcttcgccct tcgcacgatg cagttggcgc aaatgtacgg
    12901 ctatgtcatt ccagagacac tctccgtcat tagcttcaac aactcgatct tctcaacatt
    12961 aacacaccct taccttacaa gtatcgatat cgatatctcc gaattaggac gtgtcgctat
    13021 gcaaaagctg cgcgaattga tccatgaaga attgagcagt ggcgtacgtt tggtcatccc
    13081 tcatcgcttg atcaaaagag agacagtcgt tcctttagaa aacccatact aaatagctga
    13141 ctcactaaat acgctgacca tttatcctat ggtcagcttt ttatgtaaaa gaagatacta
    13201 cttctaacac attgtttatc tgtaaaaaag agcgtgggac aaaagtaaag aacacttttg
    13261 tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct
    13321 gaaattcaca aaaatttaaa aagcaatttt cttgagtttc ttcttatttc ttggagttaa
    13381 acgcttctgt cccagcctct tttttccttc cttcaatttt ttacacgtcg acgattcaat
    13441 aaaaaaccgc ctaatattgt aaagacaggt gcaagaatcg agaaaaaggc gaatggcaag
    13501 taatgcaacg cgctaacttt catcgttccc ataatgaatg tgccgctgac tccccacggt
    13561 acgagagaat tgacggtcgc acctgaatcc gctagtgttc gtgtcaaata ggtttttgat
    13621 aagccaacgt catcaaaaga acgcttgaat gtttctcctg gaagaatgat ggacagatac
    13681 tgttctccaa cgatcagatt gattccgata cagctcaagg cagtaaaccc gactaaacga
    13741 gaaggtcggt ccatcttttc ttttaattct tgaacgatgg tatcaacgat cagatatttg
    13801 atcagtaacc cacctaatgc caatgcaagt aaaatcaaac tagcagaacc taacatactc
    13861 atgatcccgc ctcgagaaag cagttcatct agctttggat caggtgtatt tgcgacataa
    13921 ccattcatca agatgtctgc tgcttttccg accgtcaaac ttttctcatg gataaaagaa
    13981 agaacgagag cagctgtcga tcccgctagt aatgtaggga tagccggaat ctttttgatt
    14041 gcccccccaa ataaaataac tagtggaatc aatgtccaag gagagatcca aaagctcgct
    14101 ttcatgtttt ggatcatttc attgatacta gctagatcgg ctgaatgact gttatgtcct
    14161 aatatcgtat aaaaaatcaa cgaaaggacg aatgctggga aatccgtata acgcatacca
    14221 gcgatatgtt cgaatagatt aactcctcca atacccgctg ccaagttggt cgtatctgat
    14281 aaaggcgagc agttattccc taaaaaggca ccggaaacga ctgcgcctgt agtcattgca
    14341 tcattgaatc caagtaaatg accgatcccc aaaaaagcaa ttccaatcgt cgaaatcgtt
    14401 gtaaatgaac tgccgacagt cactccgaca attgcacaaa caagaaatgc tgtcggtaaa
    14461 aagaaacgca cagaaacaag tttaaatcca taaaccataa tcgtagggat ggttccagat
    14521 aaaatccatg aagcaactaa gacaccaatc aaaagaaaaa tcaggattgg aatgatccct
    14581 ggagtgattc ctttgatgat tccgtcatgg atctcatccc atgtgaactt tttaaatctg
    14641 ccataaaaca acaaacacat gaaagctgca aggatcggga tatgtggcga gagctggaat
    14701 ccgatgatca gtactcctag gagtgccaac aacacgatca atacagcgat actttctttt
    14761 aaagaaatat ttttattcat cgtcgatctc ctatttcaaa tgaaaaggcc ctgccatgaa
    14821 aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg gctgaaagac
    14881 ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
    14941 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
    15001 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
    15061 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
    15121 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
    15181 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
    15241 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
    15301 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
    15361 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
    15421 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
    15481 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
    15541 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
    15601 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
    15661 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
    15721 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
    15781 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
    15841 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
    15901 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
    15961 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
    16021 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
    16081 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgttga aagctcaccg
    16141 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
    16201 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
    16261 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
    16321 ctccttgatt ttttggataa aataacgatg tctttgaagt agtttcagca ataaacgaaa
    16381 caattcagcg aatatttgag gggattcttt gagtctattg cttgaagggt ttcttcaaag
    16441 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
    16501 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
    16561 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
    16621 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
    16681 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgtg aatcctagtt
    16741 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
    16801 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
    16861 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acgtagtcta
    16921 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
    16981 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
    17041 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
    17101 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
    17161 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
    17221 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
    17281 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
    17341 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
    17401 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
    17461 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
    17521 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
    17581 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
    17641 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
    17701 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
    17761 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
    17821 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
    17881 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
    17941 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
    18001 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
    18061 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
    18121 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
    18181 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
    18241 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
    18301 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
    18361 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
    18421 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
    18481 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
    18541 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
    18601 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
    18661 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
    18721 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
    18781 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
    18841 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
    18901 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
    18961 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
    19021 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
    19081 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
    19141 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
    19201 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
    19261 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
    19321 tgggatcgtt aaaccgaacg cttctacttc tggtccttct aattttcgga ttaggtctaa
    19381 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
    19441 tttatgcaga tgcaaaaagt cgatagattg cagaatttgg taagtaaact ctgtaaatga
    19501 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
    19561 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
    19621 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
    19681 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
    19741 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
    19801 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
    19861 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
    19921 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
    19981 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
    20041 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
    20101 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
    20161 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
    20221 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
    20281 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
    20341 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
    20401 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
    20461 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
    20521 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
    20581 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
    20641 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
    20701 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
    20761 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
    20821 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
    20881 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
    20941 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
    21001 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt taaatgattt gatccaaaaa
    21061 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
    21121 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
    21181 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
    21241 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
    21301 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
    21361 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
    21421 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
    21481 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
    21541 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
    21601 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
    21661 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
    21721 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
    21781 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
    21841 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
    21901 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
    21961 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
    22021 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
    22081 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
    22141 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
    22201 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
    22261 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
    22321 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
    22381 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
    22441 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
    22501 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
    22561 tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga aagtatcaag
    22621 ctagcaattc cttgtttatg aattcattga cagaaattta taaaaagaat attatgtact
    22681 aaaataataa aaaaagtttt ataaaaaggt ataaaacctt tttattaaac tatttaatct
    22741 tgtttagtat atatttttag aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc
    22801 acacatttga aaaagagctt tggtcgtttc gaagctttaa aagatgtctc tttcaccgta
    22861 cattcaggtg aagtcgttgg atttatcgga ccaaatggtt ctggaaaatc cacgacgatt
    22921 cggacacttt tagggattat aaaaaaagac ggcggaacgg caacgatttt tgggcaagat
    22981 gtatgggaag atagtttatc tatccatgaa cgtctttctt atgttccagg cgatatctct
    23041 ttgtagggaa atttgactgg aggagcgatc atcgatctct tcatgaagct tcatggaaaa
    23101 gggagtgctc aaaaaaaaga tgaactgatt caacgtttct ctcttgatcc taagaaaaaa
    23161 gcaaaaaact attcaaaagg aaatcgccaa aaagtgggct tgattgctgc tttggctgtt
    23221 gattcggatc tctatttatt tgatgagcct acttctggtt tagatccttt gatggaaacg
    23281 attttccaag aagaagttga aaaattgaaa gaacagggca aatccatcct actttcttct
    23341 catattctca gtgaagtcga gcgactagcg gataaagtcg tgatcatacg cgaaggaaca
    23401 gtcgtagaag aaggaacact cgatgaattg cgtcatttga ctcgttcgac catcactata
    23461 gaaacagaag cagagaatag tcacttagca caattgaacg gtgtccatga ctttgtgcaa
    23521 aaaggtcacc tcgctcaatt tgctgctgat aacgaagctt tcgatgtgat tttagctgaa
    23581 gcgtccaaat taggtgtgaa aaaatttgaa tctattccac cgactcttga ggatttattc
    23641 atgagacatt atgaaggatg aggaggaagc gaaatgactg ataaattttc acgctggtcc
    23701 accctttttt ctcaaaacct tagccgtgac tggaaaaaga tcctgatatg gctagtcggt
    23761 gtcactgctt tttctggtgg ttttgtccct gcgtttgaag aattgacttc cggacaagga
    23821 ttagctggat tatacgaaac cttgcaaaac ccggcaatga ttgcaatggt cggaccaact
    23881 ccagcttcga atgctgctga gtatacttta ggagcgatgt atgcaaatga aatgttgctt
    23941 ttttgcagtt tgtttgctgc tgtgatctct gttttacacg tggtgagcca aacgagaaaa
    24001 aaagaagaac ttggtctgat tgaacttatt cgttcctttc gagtcggacg tcaagcaaac
    24061 tctttagctg tcatcgctga aagtattctg atcaatttgc ttttagcaat atcgatcagc
    24121 tgtacgatga tttttttcca agcagattcg atcactgcag aaggtgcttg gctttttggg
    24181 ctatctgtag gtagtatggg gattttgggg agtgccgttg cactgtttgc tgcacaactg
    24241 atgccaagtt cagccagttc gaatggtctg tctttagcgt ttttaggtgg actttacctt
    24301 ctacgagcaa taacagatgt agctgattcc tccctttcga tgtggaatcc tttaggctgg
    24361 tcttatttga cctatccatt tacaactaac aactggattc ctttgcttta tttgtttttg
    24421 ttcagtctaa tcttgataat cagttcattt gttttagagg aacatcgaga tttgaacacc
    24481 ggctatatcc ccgaacgtga aggaaaaccg tatgctaaac gttctctttt atccttgcgt
    24541 ggtttattat tctatctaaa taaagggatg acaatcagtt ggcttatcac ttttggtttg
    24601 atgggggcgg catacggctc tatctacggg aatatgcaac agtttttaga aagtaacgac
    24661 ttaatgaaac agatgtttat ccaatctggc gtctcaattg aaaaaaactt tacaagcacg
    24721 atcatggtcg tcttgatttg tctagctgct attttaccaa ttgctagcat caatcgttta
    24781 tttacagaag aaacccacgg acgtatgaat cagctgttcg caacaaaaat ttctaggaac
    24841 caactttatt ggaccaatat gttactagct attctatttg ctatattggc aatcctgatt
    24901 agttctggtg cactagggct ttctgctttg gcttcgatga aggatgcgaa agacatggat
    24961 ctattgatgt ttcttaaagc cgggttcaat ttcctgcctg ccgttttagt gtttatcgga
    25021 attagtggct ttctattcgg atggcttcct cgaatgggta aacttgctta tatctactta
    25081 gcttactcct ttgcactcaa ttactttggc ggaattttgg atttaccaga atggttttcc
    25141 aaaacagctg tccctagctg ggttccacgg atgccaaacg attcttttga tctttccgtg
    25201 ttccttacgt tatcatgtat cagccttgca ctgttcgtcc ttggttctat tggttatagg
    25261 cgaagagact tactagaagg ataataaaaa agcatgtaca atttcatgct agcctccaaa
    25321 tctgggtcaa aaatccaaca tttggaggtc atttttttat ttacaagtct tctaactgct
    25381 ctttatcaat gatccagact tctcgattct ttctttttac ataaccattc tcctctaata
    25441 atttaaattt tctagataaa gtttcggggg tcgtaccgat aaatgcagca agttctttca
    25501 ttttcattgg caggaaaaag tgatccttcc ctgtcgcttt agctaagtca agcagataga
    25561 cagcgactcg ttcttctact ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg
    25621 ttaatttctc aacgttgatt gctaaaagtt tcagactaag ggcgggataa tgcagtaaga
    25681 gttccgagaa atctttttgt ctcaatatgc aaatttccgt tttttctagt gcttcgccaa
    25741 ataaagactc atttggaacg cctagcaact ggctctctcc ctcatatccg cccggctcta
    25801 ttactcgtaa aagctgttcc tttccgctag cagataattg atacactttc atactgccgg
    25861 aggccacgat cactaattga ggttctccat tcggcgcaag aatctgttct cctttttcca
    25921 catagtgatg tttgacaagt gcgtgtactt tttcttgatc ttgctgtact aagtgattga
    25981 acaaaggaac aaatgaaaca cataaatgat catgactcat aatctctcct ccttctaaac
    26041 agctatttct aataaagaaa cataacttcc cttattccaa ctgataattt tcttttatca
    26101 tagcataaac gtcaagcgaa ccagatacca gcaaatagag tggatttctt tttgtccctt
    26161 gctttatttt ccttcttttg agaccttaag taattgattc ctatcaattt tttaaatatt
    26221 tactttttga ataatcaaaa acaaaccttc actcgcaagc cgagagtaag gtttgttttt
    26281 cgcattgctt atttcgtgtt gtctattgaa atttttccgc acctagcttt tgatatagtg
    26341 gtgctagttc ttgtaaggtt tcagcggtta tttgctcaac gtgttcgatt tcttgcggat
    26401 agaagaatag tttacccatt tgaaaggttc ggtctctcat cgcttttttc aactcttctt
    26461 gtttctttgt atcggacaaa tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg
    26521 gttgcggcca tatgtaataa tccttgatat cgactgtttt gctccactct ttcagtatcg
    26581 caagcaactg gttatacgct gcaatgctac catatcgttc ttcgctttta taatgttggt
    26641 acatcaaata gatttggtat tgtttttgat tcaacaaaac tgctagacag gcattctcgt
    26701 cttgacgaga ttcgcttcgg tacgcgctcc aaaaatgact gcgtaaattc cagccattcg
    26761 tccagctttc gattttaggt ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct
    26821 ggagctgaat ctctttccat ttttgccagt gttctttata ttctttcttg atttgttcaa
    26881 tcttatctgt tggatggctc tctttgagct gtttgaatgc gtagattggt cgatcaaaca
    26941 actgataatc tgattttcca agttccattg tttcgcctct ttccgttatc ttttgtattc
    27001 tacctgaatt ttgcgatatg gacaaataga ggttgtgaaa aagctgttct gcatcaagtc
    27061 ataagaacag ccaaacaaaa aactgcgatg agcatcaccg cagttttatt gaacttaagg
    27121 ttgattgatc acatctaaaa gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc
    27181 gatatgtccg attgcacgct ctcctagata ggaagctcgt ccttttttag ctaccaagac
    27241 tttggtgtgt tcttttgcct ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc
    27301 ctctgtgact ggcagccaaa catctaacat cgttttatcg tcagcttctg cctttcctcg
    27361 gctttgaata cccgctgttc cctgctcgat cacttcgcct aatttttctt gagaatcaat
    27421 agaatcgacc tcttttgtcg ctttcatcat gttcatgaat gcagatccgt ataacggacc
    27481 agaagcccca ccgactttcg atatcatcgc catagagaat actttgaatg tatcgctgat
    27541 tgtttcagga tgatcggctt gaaaagcttc ttcataagct gaaacccctc ttcccatgtt
    27601 atttccatgg tctccatcgc caatcggggt atctagatca ctgagatatt gtttgttctg
    27661 attgattgcc tctgcaaatt gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat
    27721 attatcaccc ttttatcttg agatttttta ccatgaaatc gtctgtacat tgctttctaa
    27781 agaatctttc cattgtgtct ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc
    27841 tagtgaggtc ataaaattac cgacttttcg gaaaactaca ttgacgcctc tttcttccaa
    27901 cagagctaaa acatcattca tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc
    27961 gttgactagt acacctgctt cttttggtaa attcgagtaa tcatctaaaa tcttagtaac
    28021 aagttccttt gccagtactt tagaaggctg catcttttct cgacgatagc ctggctcacc
    28081 gtggatacca acaccatact cgatctcatc ttctcctagt tcgaatcctg gtttccctac
    28141 ttctggtaca gttgctgctc gaagcgctag accgatcgtc ttagttgcct gtacgacctt
    28201 ttctcccagt tctttcaact cagctaggga agcaccgttt cttgctgcat cgcccacgat
    28261 tttgtgtaca aggacagtac ctgcaactcc gcgttttcca gcagtatacg tactattttc
    28321 aacggcgata tcatcatcta cgatcacact ttctacttca atatcgtcca tagcagctaa
    28381 ttcctttgcc atatcgaagt tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac
    28441 tccttttcca ctatccgctt ccttaatagc cgtctgaatc tgatctggag ttggagaagt
    28501 aaacacatca ccaagcaccg ctgcacttaa catcccttcc cctacaaacc cggcatggga
    28561 tggttcatgt ccgcttcctc caccagaaac caaaccaact tgttccgctt tctgattctt
    28621 ggctacaaca cgggaagatt ctacacgatg aacaagttct ggatagcttt ttactaatcc
    28681 ttccagcatt tcttcgacaa tattgcttgg atcattcatg atttttttca atttattccc
    28741 atcctttctt tccggcattt tgtgcttctg ttaagatttg ctgagtatca tctgttatac
    28801 cggcagtgat ggctgctgca aaagctcctt ccactaaagg cgcatccacc agatgataac
    28861 gttgctgctg ctcttcttcc aacatgtctt ttgccagttc cgagttcaat accgcgctac
    28921 cgatatccgc aaaaacaaaa taactagctg catcgcttga ttcattgact gcttctacga
    28981 ttttcatcgg gtctgatccg atctcgccat ttattccgcc gagagaaaaa atttgcacct
    29041 cttcggattt ttgcatctgc tcaatcattt ctttaatacc atctgttact ttttgactat
    29101 gagaaataag caaaatactt tttttcacaa gaatcttcct ttcttttaca tagttgctaa
    29161 cgattggttt cgctttcatt aatgaacaat tcaagtatat aataaatttc taattttggg
    29221 aaaatatgtg tagtgcttct tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg
    29281 aatgattaca acaacaacga acagtgtaga gggaaaagcc gtagtagctt ataaagggat
    29341 cgtttttggt gaggtcatta ctgggatcca tgcatttaaa gacttggagg cggggttgcg
    29401 aaatatcttt ggcggccgct caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga
    29461 agcacttgcc gaaatggccg aacgtgcaaa agcattagga gctgatgcga tcattggcgt
    29521 aaaaatggac tatgaagtat taggcagcga caatggcatg ctgatggtca catgtagtgg
    29581 aacagctgtc tccacgagat aagtagggga catctgtttt aataa
//
LOCUS       DAXLPQ010000031        29023 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.031, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000031 DAXLPQ010000000
VERSION     DAXLPQ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.031"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            12..84
                     /locus_tag="ACF3UO_001638"
     tRNA            12..84
                     /locus_tag="ACF3UO_001638"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="ACF3UO_001639"
     tRNA            88..160
                     /locus_tag="ACF3UO_001639"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="ACF3UO_001640"
     tRNA            168..249
                     /locus_tag="ACF3UO_001640"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="ACF3UO_001641"
     tRNA            267..339
                     /locus_tag="ACF3UO_001641"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="ACF3UO_001642"
     tRNA            351..422
                     /locus_tag="ACF3UO_001642"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="ACF3UO_001643"
     tRNA            439..524
                     /locus_tag="ACF3UO_001643"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="ACF3UO_001644"
     tRNA            535..608
                     /locus_tag="ACF3UO_001644"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="ACF3UO_001645"
     tRNA            618..691
                     /locus_tag="ACF3UO_001645"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="ACF3UO_001646"
     tRNA            711..783
                     /locus_tag="ACF3UO_001646"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="ACF3UO_001647"
     tRNA            811..884
                     /locus_tag="ACF3UO_001647"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="ACF3UO_001648"
     tRNA            898..971
                     /locus_tag="ACF3UO_001648"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="ACF3UO_001649"
     tRNA            995..1084
                     /locus_tag="ACF3UO_001649"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="ACF3UO_001650"
     tRNA            1097..1170
                     /locus_tag="ACF3UO_001650"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="ACF3UO_001651"
     tRNA            1189..1264
                     /locus_tag="ACF3UO_001651"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="ACF3UO_001652"
     tRNA            1266..1336
                     /locus_tag="ACF3UO_001652"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="ACF3UO_001653"
     tRNA            1350..1423
                     /locus_tag="ACF3UO_001653"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="ACF3UO_001654"
     tRNA            1448..1535
                     /locus_tag="ACF3UO_001654"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="ACF3UO_001655"
     tRNA            1557..1628
                     /locus_tag="ACF3UO_001655"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="ACF3UO_001656"
     tRNA            1651..1740
                     /locus_tag="ACF3UO_001656"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="ACF3UO_001657"
     tRNA            1753..1826
                     /locus_tag="ACF3UO_001657"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="ACF3UO_001658"
     tRNA            1845..1917
                     /locus_tag="ACF3UO_001658"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="ACF3UO_001659"
     tRNA            1921..1993
                     /locus_tag="ACF3UO_001659"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="ACF3UO_001660"
     tRNA            1998..2068
                     /locus_tag="ACF3UO_001660"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="ACF3UO_001661"
     tRNA            2081..2154
                     /locus_tag="ACF3UO_001661"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="ACF3UO_001662"
     tRNA            2166..2237
                     /locus_tag="ACF3UO_001662"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /gene="metK"
                     /locus_tag="ACF3UO_001663"
     CDS             2503..3696
                     /gene="metK"
                     /locus_tag="ACF3UO_001663"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFD3657668.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="ACF3UO_001664"
     CDS             3826..5298
                     /locus_tag="ACF3UO_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFD3657669.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="ACF3UO_001665"
     CDS             5381..6169
                     /locus_tag="ACF3UO_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3657670.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="ACF3UO_001666"
     CDS             complement(6236..6904)
                     /locus_tag="ACF3UO_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFD3657671.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="ACF3UO_001667"
     CDS             7019..8731
                     /locus_tag="ACF3UO_001667"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657672.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10503
                     /locus_tag="ACF3UO_001668"
     CDS             8734..10503
                     /locus_tag="ACF3UO_001668"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657673.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10708..11274)
                     /locus_tag="ACF3UO_001669"
     CDS             complement(10708..11274)
                     /locus_tag="ACF3UO_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3657674.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(11274..12230)
                     /locus_tag="ACF3UO_001670"
     CDS             complement(11274..12230)
                     /locus_tag="ACF3UO_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFD3657675.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(12230..12886)
                     /locus_tag="ACF3UO_001671"
     CDS             complement(12230..12886)
                     /locus_tag="ACF3UO_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD3657676.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            13256..15274
                     /locus_tag="ACF3UO_001672"
     CDS             13256..15274
                     /locus_tag="ACF3UO_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3657677.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    15344..15550
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15701..18115
                     /gene="leuS"
                     /locus_tag="ACF3UO_001673"
     CDS             15701..18115
                     /gene="leuS"
                     /locus_tag="ACF3UO_001673"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFD3657678.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            18463..20016
                     /locus_tag="ACF3UO_001674"
     CDS             18463..20016
                     /locus_tag="ACF3UO_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFD3657679.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(20397..22181)
                     /locus_tag="ACF3UO_001675"
     CDS             complement(20397..22181)
                     /locus_tag="ACF3UO_001675"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657680.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(22196..23917)
                     /locus_tag="ACF3UO_001676"
     CDS             complement(22196..23917)
                     /locus_tag="ACF3UO_001676"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657681.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            24017..24778
                     /locus_tag="ACF3UO_001677"
     CDS             24017..24778
                     /locus_tag="ACF3UO_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3657682.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            25745..26013
                     /locus_tag="ACF3UO_001678"
                     /pseudo
     CDS             25745..26013
                     /locus_tag="ACF3UO_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            26685..>29023
                     /locus_tag="ACF3UO_001679"
     CDS             26685..>29023
                     /locus_tag="ACF3UO_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3657683.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATP"
BASE COUNT         9098 a         5223 c         6191 g         8511 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
    10561 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
    10621 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
    10681 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
    10741 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
    10801 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
    10861 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
    10921 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
    10981 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
    11041 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
    11101 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
    11161 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
    11221 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
    11281 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
    11341 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
    11401 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
    11461 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
    11521 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
    11581 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
    11641 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
    11701 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
    11761 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
    11821 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
    11881 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
    11941 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
    12001 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
    12061 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
    12121 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
    12181 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
    12241 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
    12301 acagccaaga aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca
    12361 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
    12421 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
    12481 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
    12541 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
    12601 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
    12661 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
    12721 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
    12781 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
    12841 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
    12901 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
    12961 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
    13021 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
    13081 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
    13141 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
    13201 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
    13261 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
    13321 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
    13381 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
    13441 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
    13501 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
    13561 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
    13621 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
    13681 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
    13741 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
    13801 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
    13861 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
    13921 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
    13981 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
    14041 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
    14101 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
    14161 ggaaaatggc tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg
    14221 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
    14281 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
    14341 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
    14401 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
    14461 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
    14521 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
    14581 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
    14641 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
    14701 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
    14761 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
    14821 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
    14881 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
    14941 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
    15001 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
    15061 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
    15121 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
    15181 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
    15241 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
    15301 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
    15361 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
    15421 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
    15481 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
    15541 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
    15601 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
    15661 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
    15721 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
    15781 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
    15841 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
    15901 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
    15961 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
    16021 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
    16081 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
    16141 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
    16201 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
    16261 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
    16321 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
    16381 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
    16441 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
    16501 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
    16561 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
    16621 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
    16681 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
    16741 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
    16801 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
    16861 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
    16921 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
    16981 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
    17041 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
    17101 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
    17161 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
    17221 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
    17281 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
    17341 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
    17401 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
    17461 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
    17521 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
    17581 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
    17641 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
    17701 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
    17761 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
    17821 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
    17881 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
    17941 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
    18001 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
    18061 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
    18121 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
    18181 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
    18241 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
    18301 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
    18361 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
    18421 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
    18481 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
    18541 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
    18601 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
    18661 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
    18721 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
    18781 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
    18841 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
    18901 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
    18961 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
    19021 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
    19081 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
    19141 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
    19201 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
    19261 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
    19321 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
    19381 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
    19441 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
    19501 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
    19561 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
    19621 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
    19681 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
    19741 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
    19801 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
    19861 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
    19921 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
    19981 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    20041 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    20101 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    20161 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    20221 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    20281 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    20341 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    20401 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    20461 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    20521 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    20581 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    20641 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    20701 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    20761 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    20821 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    20881 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    20941 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    21001 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    21061 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    21121 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    21181 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    21241 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    21301 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    21361 aaggcgagtt gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca
    21421 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    21481 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    21541 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    21601 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    21661 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    21721 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    21781 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    21841 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    21901 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    21961 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    22021 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    22081 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    22141 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    22201 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    22261 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    22321 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    22381 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    22441 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    22501 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    22561 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    22621 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    22681 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    22741 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    22801 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    22861 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    22921 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    22981 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    23041 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    23101 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    23161 aagcataaac gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt
    23221 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    23281 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    23341 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    23401 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    23461 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    23521 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    23581 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    23641 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    23701 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    23761 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    23821 gtacacctaa tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc
    23881 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    23941 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    24001 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    24061 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    24121 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    24181 tttttataga aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt
    24241 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    24301 gatgaaacaa aaacaaaaag agataaggga gcgaaaaaaa cagttgaaat tgatgatcga
    24361 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    24421 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    24481 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    24541 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    24601 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    24661 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    24721 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    24781 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    24841 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    24901 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    24961 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    25021 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    25081 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    25141 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    25201 aatcaaatag tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt
    25261 tttgcttata aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag
    25321 aaaaatcaca aaggttattg ttatttttat atattctttt taagaatgat tattttttta
    25381 tagaaatttt aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata
    25441 ttatagaagt tgactggtag tgatttattt ttcgttgttt tataaaaatg ttattttttg
    25501 gaaaaattca caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta
    25561 tgactaatat aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg
    25621 gaatcaatga aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat
    25681 agcaatacat cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac
    25741 aacaaaagga ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt
    25801 tattctatac aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa
    25861 tatatggtac agaatataga aattattgac attacagaaa atgatgaaga tttaatacag
    25921 attgtcacta tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg
    25981 attaaggagt tgatggaaga cgatacaagt taagaaagta aaactacgcc caaataaaga
    26041 gcaaaaagag taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt
    26101 ttattagtaa tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg
    26161 tttagttgaa ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc
    26221 caagtattct aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt
    26281 gatgaaggtt aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc
    26341 aacgatttag tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa
    26401 taactattag ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca
    26461 taattatggt taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac
    26521 agaagacaat cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa
    26581 ccgaaaatac gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta
    26641 tcgggtacct tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc
    26701 ataaactgtt aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa
    26761 cggttctagc tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc
    26821 aagaggaggc tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc
    26881 taaatgcatt ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca
    26941 atgattacga acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg
    27001 caagaagcgg tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa
    27061 gcacaagtga gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag
    27121 aagaaagctt aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg
    27181 aatctcagat tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc
    27241 gccccacttt gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg
    27301 gcgatattct tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct
    27361 taattgagtt cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt
    27421 accaagaagg cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag
    27481 ccgctcagtc gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta
    27541 ctgagccaaa taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg
    27601 aattttcaat tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct
    27661 ctagagaaat cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga
    27721 ccaacagtaa taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag
    27781 tggttaccga tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt
    27841 ccactggaaa tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag
    27901 gtgaagcaaa cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta
    27961 ataaggaaac gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt
    28021 ttattgaata tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg
    28081 atgggttttc tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact
    28141 accgcttgag aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca
    28201 aaaatgttat caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt
    28261 ctggaacaag caatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt
    28321 catttctatc agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt
    28381 tcagtgcgaa taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg
    28441 tagaggcgta tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca
    28501 atcgattgaa tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta
    28561 aaactgatga gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt
    28621 cacaagtgat acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc
    28681 ctgtaggtag ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga
    28741 cggtacatga tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa
    28801 acatccttga tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc
    28861 ttcaaggagc tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggtttaa
    28921 ctacaggaga agatggaaaa ctggcaattg acggtttagc accaggagca tatcagctgg
    28981 tagaaactca agcgccaata gggtatgaat tagatgcgac acc
//
LOCUS       DAXLPQ010000032        28196 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.032, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000032 DAXLPQ010000000
VERSION     DAXLPQ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.032"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..416
                     /locus_tag="ACF3UO_001680"
     CDS             <1..416
                     /locus_tag="ACF3UO_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3657684.1"
                     /translation="VCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLVLWEKKKTSV
                     KELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAALQKQAEGIP
                     QKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            525..1604
                     /locus_tag="ACF3UO_001681"
     CDS             525..1604
                     /locus_tag="ACF3UO_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3657685.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(1730..3019)
                     /locus_tag="ACF3UO_001682"
     CDS             complement(1730..3019)
                     /locus_tag="ACF3UO_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3657686.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            3167..4720
                     /locus_tag="ACF3UO_001683"
     CDS             3167..4720
                     /locus_tag="ACF3UO_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657687.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            complement(4828..5910)
                     /gene="uxuA"
                     /locus_tag="ACF3UO_001684"
     CDS             complement(4828..5910)
                     /gene="uxuA"
                     /locus_tag="ACF3UO_001684"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFD3657688.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5901..7547)
                     /locus_tag="ACF3UO_001685"
     CDS             complement(5901..7547)
                     /locus_tag="ACF3UO_001685"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFD3657689.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7731..8393
                     /locus_tag="ACF3UO_001686"
     CDS             7731..8393
                     /locus_tag="ACF3UO_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3657690.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8537..9100
                     /gene="ahpC"
                     /locus_tag="ACF3UO_001687"
     CDS             8537..9100
                     /gene="ahpC"
                     /locus_tag="ACF3UO_001687"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFD3657691.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            9110..10639
                     /gene="ahpF"
                     /locus_tag="ACF3UO_001688"
     CDS             9110..10639
                     /gene="ahpF"
                     /locus_tag="ACF3UO_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFD3657692.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            10796..11146
                     /locus_tag="ACF3UO_001689"
     CDS             10796..11146
                     /locus_tag="ACF3UO_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFD3657693.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            11245..11775
                     /locus_tag="ACF3UO_001690"
     CDS             11245..11775
                     /locus_tag="ACF3UO_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFD3657694.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            11929..13080
                     /locus_tag="ACF3UO_001691"
     CDS             11929..13080
                     /locus_tag="ACF3UO_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFD3657695.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(13189..15228)
                     /locus_tag="ACF3UO_001692"
     CDS             complement(13189..15228)
                     /locus_tag="ACF3UO_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFD3657696.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIPDKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15286..15843)
                     /locus_tag="ACF3UO_001693"
                     /pseudo
     CDS             complement(15286..15843)
                     /locus_tag="ACF3UO_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     regulatory      complement(15991..16157)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(16382..16588)
                     /locus_tag="ACF3UO_001694"
     CDS             complement(16382..16588)
                     /locus_tag="ACF3UO_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657697.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(16604..17218)
                     /locus_tag="ACF3UO_001695"
     CDS             complement(16604..17218)
                     /locus_tag="ACF3UO_001695"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFD3657698.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(17365..18048)
                     /locus_tag="ACF3UO_001696"
     CDS             complement(17365..18048)
                     /locus_tag="ACF3UO_001696"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFD3657699.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(18157..18615)
                     /locus_tag="ACF3UO_001697"
     CDS             complement(18157..18615)
                     /locus_tag="ACF3UO_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFD3657700.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(18699..20462)
                     /locus_tag="ACF3UO_001698"
     CDS             complement(18699..20462)
                     /locus_tag="ACF3UO_001698"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFD3657701.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(20683..22143)
                     /locus_tag="ACF3UO_001699"
     CDS             complement(20683..22143)
                     /locus_tag="ACF3UO_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657702.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(22351..23277)
                     /gene="glsA"
                     /locus_tag="ACF3UO_001700"
     CDS             complement(22351..23277)
                     /gene="glsA"
                     /locus_tag="ACF3UO_001700"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFD3657703.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(23300..24727)
                     /locus_tag="ACF3UO_001701"
     CDS             complement(23300..24727)
                     /locus_tag="ACF3UO_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3657704.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(24758..25972)
                     /locus_tag="ACF3UO_001702"
     CDS             complement(24758..25972)
                     /locus_tag="ACF3UO_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFD3657705.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(26058..26285)
                     /locus_tag="ACF3UO_001703"
     CDS             complement(26058..26285)
                     /locus_tag="ACF3UO_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657706.1"
                     /translation="MKNKFENRSDTRCGSFLYILYEVFFIPYEKISLKIKKDENKRFS
                     IKRRPFIFCLYLCEKRKRAQHIKLLLIVCLL"
     gene            complement(26313..26555)
                     /locus_tag="ACF3UO_001704"
     CDS             complement(26313..26555)
                     /locus_tag="ACF3UO_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3657707.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(26587..27144)
                     /locus_tag="ACF3UO_001705"
     CDS             complement(26587..27144)
                     /locus_tag="ACF3UO_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3657708.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(27157..27345)
                     /locus_tag="ACF3UO_001706"
     CDS             complement(27157..27345)
                     /locus_tag="ACF3UO_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3657709.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(27358..27924)
                     /gene="amaP"
                     /locus_tag="ACF3UO_001707"
     CDS             complement(27358..27924)
                     /gene="amaP"
                     /locus_tag="ACF3UO_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3657710.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         8177 a         5451 c         4936 g         9632 t
ORIGIN      
        1 aagtatgttt tcctttatat gccgcctcta aggaaatcat tagacactac acttccctcc
       61 tcaagccgct gaatcttacc tatacccagt atcttgtgat gttagtttta tgggaaaaga
      121 aaaagacttc agtgaaagag ctaggaaatg atttgtgtct ggattctggt acgctgactc
      181 ccttactaaa aaagttagca gaaaaaaatt atattaatcg tcagcgtgaa acgggtgatg
      241 aaagaatcgt aaatgttacg ctgactcctc aaggtgctgc gttgcaaaaa caagcagaag
      301 gtattccaca aaagatcaag tcttatcttc cacttgaaca ggaagaattg gatacactgc
      361 aacatctgac ccgaaaaatg ctagataatt ttcatcaaga ccagaaaaag ggctgaaact
      421 gctagatgaa cgattttatg aggaaaacca actcataaga taacgtcatt tagcggtttt
      481 tctttttgct ctttctcttt cttattttca tattccatca tataatgaat aacgtgttta
      541 ttttttgtta tttggaggtt gtcgatttga ccgtttatca gcgttttttg gcgaatgaaa
      601 aaatacgccg tctcactgtt ttattatttg tcgtttttgt tcttttctta gttagaagta
      661 tgattacaac cattttgctc acatttatct ttacttattt gatgattcat cttgttcaaa
      721 tcattcagcg atttgtccga atccctacag gtgttttagc tatcatgatt tatacactga
      781 tcgtttacct tatctatctg gcattcacaa agtatatccc gatgcttatt catcaaacat
      841 ttgatatgat ccagtccgtt attgattttt acgagcatca gccaaaagat gcagatcctg
      901 ttttacaata tatccatact tatattgagc gaaacgattt ttttgaacag cttcaaaatg
      961 gcgcttcgat tgcgcttggc tatttacagg atataggaaa aatggcagtg gcgtttgcta
     1021 tgtcattcat cttaagtttc ttttttatga ttgaaaagaa aaaaacaatt gtattctcaa
     1081 gattgttttt aaaaagtgaa ttttcttggt tctttcaaga tatttactat tttgccgata
     1141 agtttgtcaa tacatttggt ttggtattag aagctcaatt tgttatcgct cttttaaaca
     1201 cgttgctcac tacaatcgcc ttggctgtat ttggctttca tcagctgctg agtttagcga
     1261 tcatgatttt cattttaagt ctgatcccag tagcaggtgt tatcatttct tgtattcctc
     1321 tatctttcat agcttattcc caaggaggca tccgagatgt tgtttatatc ctgattacga
     1381 ttttgattgt ccatctaatt gagtcttatg tgctgaatcc gaagttgatg tccagcaaaa
     1441 cagaactgcc gattttttat acatttgtgg tcttacttgt tagcgaacgg ttctttggcg
     1501 tttggggctt gattgtcggc attccgatct ttaccttctt tttagatgta ttgaaagtga
     1561 aaaagatccc gaaccatctt ccaaaagaaa cagatatccc ttaaaataaa tatgaagaaa
     1621 gataaagtat gaacgacccc aaatatcaga tttcaatctg gtattttggg gtcgttttct
     1681 ggatatttct ttttatttga aaaatgcgtt cacagacatt attcaaatgt tagagagatc
     1741 tgttttgttt aaatcttttt gcagaaagca ttgttgctat acttaataga atgattccgc
     1801 tccacagtat aactttgttt tgtgactctc cggattttgg tagctgttta tttttcgttt
     1861 caggactagc aaaggttgta tccttgctac tttttaaggt ttcagctgat tgggcgctat
     1921 caaatattcg tgatttttta ttcagctgct cttcatttat ttttagaatt gctagatttg
     1981 attttttact ctcttttttt ccatcctctt gaattgtttt tttgtttatt ttttctggta
     2041 ttccttggtc tcttgcgtcc gtatctggtt ctggagtcac atctggtttt tcttctggat
     2101 ctacctctag tttttctgga ttttcagttt cattatctgt gtctggattt gtttccggta
     2161 ctgtttggtt tccagaatcc gtatctggtt ctggagttac atctggtttt tcttctgggg
     2221 ctacctctgg tttttctgga ttttcagttt cattatctgt gtctggattt gtttccggta
     2281 ctgtttggtt tccagaatcc gtatctggtt ctggagtcac atccggtttt tcttctgggt
     2341 ctacatctgg tttttctcca ggggttattt caggttttga ttcattgtct ggctctggtt
     2401 gagtttctgt atcgggttct tctccaggtt ctatttccgg tttctgttct ccgtctggat
     2461 tttctgtagg cggtacttct ggcttatttt cattttctgg tttatctgtt ggttcttcaa
     2521 caagatctcc tcctgagtcg atagctgaat cttgctcaat tgtctgccgc tgactatacg
     2581 gcgttaaatg atgatgatcg ttcggtagtc catctgatac cttgacagta aaaagcgctg
     2641 gttttaacaa gtcctgattt aatgtaacgg tgaaggtaaa tatcgcttgc ttgtgttgga
     2701 tagtcaaagt gttctcgtca tagccaatcg acaaagcggg atcaacattc tcaaatgtaa
     2761 cagctgattg tagtataggt gctaagtctc ctgaatagtc aatttttgct ttgatggtcg
     2821 ctgtttgtcc ttttcttaat tttgcgactc ctgaattgaa ggatgaaaat tcatcctgaa
     2881 aggtaattcg attgacgttg gcccacttgg tttctgtcca tttggctgtt tctatctcct
     2941 ctgtgtggac tgtctgattt atagtaagcg ataagcttaa ggctgcaaat gttgatatta
     3001 agatggttga atatctcata actctctcac tccttgattt ttttgtatgc aagaaataag
     3061 atagtagaga ttctacctat atgtttactg tttttttgtc taaatttatg aaaaaaacag
     3121 taatattttc aagttttaac aatttaagta aaaaggagcc tctttcatgc aaactcaaga
     3181 agcgattaaa acgtttctct tgaagaaaaa aagcaataca aaattagata tttttctttt
     3241 cctatctgaa catcgtttct ttattactac acaatattta gcagatcatt tccatatgtc
     3301 tgaatcaaat tttttactat acatcaaaga attagaacaa gactttgagc gtctcaatct
     3361 aacagaactg catattgata agcaaaaacc ttttttaaag ttgaattttg aaggaattga
     3421 tccggcttac tgctattatc gtctatttgg aagatactgc aacgaatcag tcagttatca
     3481 gatcttgact tctttgttca gctgtcagac aaattcgatt atcagtttaa gtcagcaaac
     3541 aaactatagt gcctcttatt tgtatacgaa aatgaaaaag attaatgcat ttttagcatt
     3601 gtacggtttg tctatctcct tttctaataa tggcagaaag tctttttctg gaaaagaggt
     3661 acaaattcaa tatgcagcat tagatattta ttggaacatc ttttcaagta ctgctacaga
     3721 attttatgat gaagatccgc aagtagtggc ttttatgatg aatacttttt ttaaaaaaga
     3781 agtacttgac cgactaaata gcggtatgat agataaatta tattttctat taaaaatatg
     3841 taaagagaat tttcctgcaa cttctgtgaa agacgtacaa aaagaattca cagagtatga
     3901 atatattgac ttttttattg atccctctgt agatattttg cgacctaatc tgccaatttg
     3961 tcgcgaacaa cgcatcttag tgaatatttt agctcgactt tctatcacga aaatcgaatc
     4021 ggaagaaaca agcttggagc aatacaaact tttaaaaaaa gcaaacgttc ctcatgttct
     4081 ttattcaaga gaaatggtgg agtccttttg tactgtattt gatttgttta tacctgaaaa
     4141 agaaaagatt ctttactcat tggcattcgc acgaaataaa ctttataatg gatttcttaa
     4201 cttcaatcaa ccaaatacgc cccttcctac tttcatgctt tatcaagaac atagcgtgtt
     4261 gaaagaagtc caaaccgcca ttgaacaatt ttatatggat ttcagagaac aaaatcaaca
     4321 cttgttacca gttattttag aaaaggaaaa tgtgcaatgg atggttgaag acctagtaca
     4381 tttgtatgat cgctacaaaa aacagccgcg aattgtgatt ggtgtgaact atacgcgtga
     4441 tttttatatc agtaaagatc tgatcgttaa gatagaacaa attttttcaa atgaatcgat
     4501 caaaatacaa aatgatttta tggagaactg caacatcgtt atcagcgact gccctttgaa
     4561 acaattgcct tctcatatca aaaaaatcta tattttaaaa ggaatcatca caccagaaga
     4621 ctggaaaaaa gtgattatga ggatctcaga atatatcttt gaattaaaag aagaagcact
     4681 catggatcaa tcgaaaaaag aaaatcaagt tacttcctag accaaataag atacataaat
     4741 ccgaatgctt attaacaacc tccggattta tgtatcaaga atttgaacat ccttcttatt
     4801 tacataataa aattacagtt tttttcacta attatcttta cttttgtttc ctttttcgat
     4861 tgcttcccat aatccattta gataaacagc acctaatgct cgatcatata agccgtatcc
     4921 tggtcttcct gtctcattcc agatcattct tccatgatca ggacggatgt atccgttaaa
     4981 tccgttgtca tacattgttt ttagtatgcg gtacatgtct aatgaaccgt attcggattt
     5041 atgcggtgcc tcatagaaat ctcgattagc taaaaattta atatttcgaa catgtgcaaa
     5101 tgggattcga tctctttgac aaaattctgc taaaatccca tatacatcat tttctggatc
     5161 ttctgcaata ctccctgtac aaagagtgat tccgttataa gggctgtcta ctatgcggca
     5221 caaccaatct aaatcttctc gattctttac gattcgaggt aatccaaaaa tcgagtatgg
     5281 cggatcatct ggatgtacag ccattttgac ccctacctct tcacatgttg ggatgattga
     5341 ttggagaaaa taggcaaaat tttctcgaag tttttcttcg tctactgatg cataggcttc
     5401 aagcaaggat ttgatatgag ctaagcgctc aggttcccat cccggcaatt caaattcatt
     5461 gctggaatgt tcgatgcgcg cgacgatttc tcttggatca tctggaatat catcagatat
     5521 aaaagctaac gtggatgagc cgtcttctaa gcggtagtca aggtcagatt tcacccagtc
     5581 aaatacaggc ataaaattat agcagatgac ttctattcca tattctgcca agtttcggat
     5641 tgtctgctta tagttttcga tatactgctc acgggaaggt aatccaattt taatggcatc
     5701 atgcacattg acgctttcaa ttacttttag tgttaaccca cgagactcaa tttcttcttt
     5761 tagttctttg atcctctccc taggccatac ctctcctact ggtatatcca tcaatgtgcc
     5821 tacaatccct ttgaccgcag gaatctgtct gatttcatct aaggtaatct tttcttcctg
     5881 tgatccgtac catctaaaag tcatttccat gataaatttc ctccatgttc ttgtaagtaa
     5941 tcctgtaatg tttttcgtac ggcattcggt cctgctacca tcttgatgaa catttcttct
     6001 atttttctgc caagctctgc ttggtaaaga tctacaccaa aaatttcttt atttgacaaa
     6061 ataggagcca ttttctcatg aatatgtgat gtatcttgcg tacccagttg aatatcggaa
     6121 agcttatgct gaaagtctgt caatagtggg tctggactcg ggatgaatgg ttttccttga
     6181 tcatcaatgc caataaggta tcgaagccaa gcagcgagag tcaatggtat gaatacaagt
     6241 gtctgcgggt ctttaacttc tatttccata tattttttaa tcgtctcacc ataacgaatc
     6301 gccacctttt gagaggtatc cgtggcgatt cgctgaggca tatcaggaat atttggatta
     6361 gaaaagcgca cagtaattac ttcttccaga aagatctttg gatcaatgat acctggagac
     6421 tccacaactg ggaggccttc attgtacccg atttcagaaa ctagcagcga taaatctgga
     6481 tctttcatct cctcagctat gctcctatac cccagtaaac aacccataat agctaaagac
     6541 gtatgcaaag gattaaggca agtcgtcacc ttcatcgtat ctgctttatc taccgttgca
     6601 cgatcagtca agaatacccc agctttttcg aatttcggac gtccattggg aaaatgatct
     6661 tccatgatta aataatggat gtcctctgta ttgacaaatg gagcaatatt atttcctttt
     6721 gcggtttgga aaatcgacat atttgaaaag ccctcttttg ccaacatttt gctaactgac
     6781 aaggaaggat tcggggtgat acgatcaatc atcgtccatg gaaacgcaac aatttcttca
     6841 ttcgataagt attggataaa tgtattttgt acataacctt ccttttgcca ttcttttgcg
     6901 atcgttagca aagaagtacg taattgacta ccgttttgtg aaaaattatc tgtagagaca
     6961 agtgcaatcg gccaagctcc agataaaaaa cgtttataaa gtagcgcagc aagaatactc
     7021 attgtatgtg atggcttctt tggaccattt tttatatcga ctgcaatcgg tcctatatat
     7081 ttattatttg tatctttcaa tcgataacct ttttcagtaa tagcaaaagt aactaattgt
     7141 aaactaggat tttcaaagtg tcgaatcatc ttatcaaagt gttcagaaca atctggatga
     7201 caatacagac tgtcagctgt cgcagctaat atacgtttga cgaactctcc actgcttggc
     7261 atgaccactt caagaatcaa atcatcaaaa tcttggtaag ccctttcaat tatttcttca
     7321 tcgaatgttt cacaaacaat gacaccagtg gacaattcgc ctagatccgc taaacgttga
     7381 gcgatttctg catgaaatcc tcgataaaga tttccgccac cgaaatggat ccagacagga
     7441 tttttttgtc cattttctct taatgatgca cggtcaaaat gaggtatttc tacttctttt
     7501 tgagataatt cagggataaa gttcctccag ttgtttaaat caatcatttt tcccctccta
     7561 aactaacata ttagtttttg tattcaagtg aattttatac aataaaaatc gctatgtcaa
     7621 ccaaaatttt actatttata caaatttact agttaatgtg acataccaga ttgtttttca
     7681 gacctcttct gttatactac gttcatagaa atgattttgg aggaataaag atgaaaagca
     7741 gcttgcaatc acaagcttat caagcgattc gtaaacaaat tatctatgct gacttagaac
     7801 ctggaaggaa aatatctgaa aaggcactgg aggaacatct tgctatcggc cggactccca
     7861 ttcgcgaagc attgattcaa ctacgtcagc aagaactcgt gtatacgata cctcaaagtg
     7921 gtacgtatgt ttccaaaatt aatcttgttt ctgcagaaaa tgctcgcttt gtccgagaac
     7981 agttggaaga gcaaatcatg attgaatgtt gttccaaatt ggacacacaa acacgaatag
     8041 tgctagaaac gattttagaa gaacaagaaa aagcagtcaa aataaatgac gaacgcgctt
     8101 ttttccgtgc agataattta tttcatgaag cttgtttcga aattgcagga agaaaagaag
     8161 tttggaactg gttagatgac cataataccc atttagaacg tttccgctgg ttacgagtga
     8221 ccattcaggg gcttccatgg gaaacgatca tggaacaaca ttatgattta ctcaaggctt
     8281 tagttgataa aaaaccagaa gaagctcgat ttcaaacggg attgcactta cacatgatgc
     8341 tgaaagaaca ggaaactgtt actcaacgtt atcccgagta tttccagcag tagcattttc
     8401 ttgcgacctc ttctattttt ataattaacc ttcgtttttg agtaatcttt attaaataac
     8461 aaaatatcca ttgactttgc aactccaact aaattacaat aattataaat aaataattat
     8521 tattggaggt tttactatgt cattgattgg gaaaaaaatc gaagaattta atgcacatgc
     8581 ttatcatcaa ggagaatttt tagaagtcag tgaaaaagat cttatgggga actggagtat
     8641 tctttgcttc tatccagctg attttacttt tgtttgtcct actgaattag aagacttaca
     8701 agaacaatac agtacattga aatctttagg tgttgaagtc ttttcttgct ctaccgatac
     8761 ccactttact cacaaagcat ggcatgatac atcagatgct atcggtaaaa tcgaatacgt
     8821 gatgatcggt gatccgtctc atcagatttc tcgtattttt gatgttttgg atgaagagca
     8881 aggattagct cagcgaggaa catttattat tgatccagac ggaatcgttc aagctatgga
     8941 aatcaatgca gatggaatcg gtcgtgacgc tagtgcactg attgataaga ttcgcgctgc
     9001 tcaatatgta cgtacccacc caggtgaagt ttgtccggca aaatggaaag aaagtggcga
     9061 aacattgaaa ccaagttttg atcttgttgg aaagatttag gtggtggata tgttagacaa
     9121 agaaactaaa caaaatctcg aacaatattt agcactgatt gaatctccta ttgttttttc
     9181 tgttagtttg gataatagtg aaaatagtca aaaactagct gaatttacga aggaaatagc
     9241 agaaatgtct cctaaaatct cttgggaaaa aagagattcg atgcgcacac ctagtttttc
     9301 tatcaatcca gttggcaaag aaagtggaat cgtttttgct ggtatccccc tcggtcatga
     9361 attttcctct tttttactgg ctatgttaca aattagtgga cgggcaccga aaatcagtga
     9421 atctttgagt cttaaaatca aaaaaataac acaaacattg cattttgaca gttatgttag
     9481 cttgacttgt cataattgcc ccgacgttgt acaggcattg aatatattag ctgtattaaa
     9541 tccaaatatt actcatacga tgattgaagg tgggatgttc caaaaagaaa tcgatgataa
     9601 aaaaatcatg gcagtgccaa ctgtgttttt aaatggagaa gaatttagta gcggacgcat
     9661 gacgatcgaa caaattgttg aaaaaatcac tggccctttg attgaagaag agttgtttga
     9721 aaaagaacct tatgatgtat tagtaattgg cggtggacca gcagctagta gtgcagctat
     9781 ctatgcagca cgtaaaggaa tccgtacagg acttgtcgct gattctttcg gcggacaagt
     9841 cgttgaaaca ctagggattg aaaatatgat tggtacctct tacacagaag gtccaaaatt
     9901 gatgcagcaa gtagaaagtc atgtgcgtag ttaccctatc gacattatga tgaatcaaca
     9961 ggccgtttcc ttaaataaag agcaacattt tattaatatt ggcttagcta acggtatatc
    10021 acttaaagca aaaaccgcca tcatcgcgac aggtgcgcac tggcgttcta tcaatgtacc
    10081 aggcgaaaaa gagtttaaaa ataaaggaat tgcttattgc ccacactgtg acggcccttt
    10141 atttaaagga aaagagattg ctgttatcgg tggtggtaat tctggtgttg aagcagcaat
    10201 cgatttggct gggttagcaa aacatgtata tgttctagaa ttcttaccag aattaaaagc
    10261 agatcaaatc ttacaggata aactagtctc tcttgcgaat gtcactgtta tcaaacatgc
    10321 agcgacgaaa gaaatcagcg gtacgaatca ggtagaatct ctctcctata tcgatcgccg
    10381 tacgatggag atgcatacac tagctgtttc aggagtattc attctagtcg gcttactccc
    10441 taatacggat tggctagatg gaacgatcga aatgaatcca agaaatgaaa tagtgaccga
    10501 gaaaaatggc gcaacgaata tccccggcgt tttcgcagct ggtgattgta cagatagtcc
    10561 atacaaacaa atcattgttt caatgggttc aggagctact gcagctttag gagcattcga
    10621 ttatctgatg cgcacttgag ctatgaagat tgtaaaaagt cagagagcgg aaaaaaggat
    10681 ggtgacaaga attttgtcac aatccttttt gtttttttga ataatcgctt tttcttctct
    10741 ttttcttata tactataagt agtaaataat ttgaaaaaaa gaaaggtgac tgattatggc
    10801 gcaaaatcgt atttttacga caagttttgc aagcgtttat cctatgtatg tagcaaaagc
    10861 ggagagaaaa gatcgtataa aagaggaagt agatgaaatc atttgttggc tgacgggtta
    10921 ttcccaaaca gaactagaat atcaactaca aaaacaagtg actttcgaac aattttttgc
    10981 ggaagcccct gtccccaatc cttcacgttc cttgattaca ggtgttgttt gtggtgtacg
    11041 agtagaagac atcgaggata acttgatgaa agaaattcgt tatttagata aaatgatcga
    11101 tgagctagca aaaggcaaaa aaatggaaaa gatcctcaga agttgatttt tccagagata
    11161 ttcttctcct tcgctcattt tgtaacattt aatttggtaa aatgactagt tcacgttaaa
    11221 ataagtcaaa ggaggttttc ttatatgttt gagacgatta aacaaaatat tcaaaaatac
    11281 gccttattaa gagctgctgt ttatattatt tctgggattg cgattgtgct aaacccttct
    11341 gctgtttttc attttatcgg ttatctgatc accgcctatc ttgttttgct tgggttgttg
    11401 aatctttttg aggcttaccg ttttaaaagg aaaacaggtt cttggagtat cggtctgttc
    11461 agtggtcttt ttttcctgat cttagctctg atcgtctatg cttttgcacc tgcaatcgtt
    11521 tctatcctgc cgattcttct tggattagct gttatcatca acagcttgtt ccagttgttc
    11581 ttcagcatga atacaaaagc taaaagttgg agtgtttata gtagtattct gttgttgatt
    11641 ggcggattcg tcttattgtt caatccattc aaaagtttga tgcttctatt ccaaatattc
    11701 ggctttattt tgattttcat gggcatccag gagattatca atttcatcag aataagaaaa
    11761 atgactatac gttaatcatt tttagttatt aaaatagacc gtataaaaac caacaatcca
    11821 aaaaaatctt ttggattgtt ggtttttttg tgagtatatt ttcctatttt ttcaataatg
    11881 tatgttatgc taagttcggg ctatatttta tacaaaggaa tgatgagaat ggaatttatt
    11941 ggtattttat gcctgatatt gatttcaaca acgattggct cacatatctc gcggagatta
    12001 ggtatcccag cagtgattgg acaattactt gttggtgttt tgctaggcca agctggattg
    12061 aattgggtca aacctgatat tctagtccat gacttttcgg agattggtgt gatcttatta
    12121 atgtttttag ctggtctgga aagtgattta tctcttttga aaaaatattt ccgacctggt
    12181 atgttcgttg ctttgcttgg gatcatcttc ccggttgttt ttggctggtt gacaggcaaa
    12241 gcattccaag tttcgggaaa tgaagcgatt ttctttggga ttattcttgc ggcaacttct
    12301 gtcagtattt cagtagaagt attaaaagaa ctaaacgtag tgaatacaaa agaaggatca
    12361 acaattttgg gtgcttctgt ggtagatgac attttagtcg ttttagttct aagtttcagc
    12421 ctatcttttc taacggggga agcttctagc aatgcttctt taccgcttgt tttgattgaa
    12481 cagctaattt attttgtttt tattttctta ttagtcaaat ggattgcgcc tttcctactt
    12541 tcatttgcag aaaaagtgta cgcaaattct tctattatca tcgtatcgct agttatttgt
    12601 ttaggaatgt cttacgtagc ggatcttgtt gggcttagct ctgtcattgg tgcttttttt
    12661 gctgggatag ctgtcagtca gacaaaggtt aaagaagaag tataccacaa tgtagaggct
    12721 ttaggatatg cagtatttat accagtattt tttgtcagtg taggattaga agttgatttt
    12781 tctgacttta gtgaacaact actctttatt tctatattga cgcttgtagc gattttgacc
    12841 aaattgcttg gaggttattt tggtgctcag attgccggtt tttctcaaca tagttcattg
    12901 atggtcggtg ctggtatgat ttcgcgtgga gaaatggctt tgatcatttt acaaattgga
    12961 cagcaaagtc aattgatcga accacagtac tattcacctt tagttatcgt gattttatta
    13021 agtacactta tttctccact tgttctcaaa tattttacaa aaaaagttta tgaagtgtga
    13081 gtaaatcaaa aagaagttgt gaaagagaca tcgtgaaaac cgtttatttg aaaaaaggac
    13141 tgtgacgata acgccacagt ccttttactg tacttaaaaa gcaatttttt attgataatt
    13201 ttggttgagg tattgcaata gttccgatgc tcgtttggtt gctgaatcat catcttcttt
    13261 attttccaac atgctgacca tcatataacc ttggttatca agattgaaag caaacaagaa
    13321 actgttctct tgccccttta catcctgttt ttctttgatt tccgctgtac cagttttcgc
    13381 tgccaacgga atccctaaag cagaaagaga atgtgctgta ccatttacat cttgcacaac
    13441 ttctctcaga tctggcacga tcgtttgtac tgctgtttcg ctgatgacat tcttcttatc
    13501 ttttgtctct ttatctggaa tcaatttagg atagacaagt gtgccattgt tggtaaaaac
    13561 agaatacatt gctgcttgct ggataggagt aattagaagt tcgccctgtc catatccagt
    13621 atcagctagc aagatatctg agttaaagct atcttcatta gaaatttgtg ctggattcat
    13681 actaattggc aaatcaaggt cttcaccaaa aatgaattta tctaagcctg tacgaaattt
    13741 tttctcaccc attttcaacg tttcttgtgc cgcatatata ttatcggaat agatcaaagc
    13801 agtttttaag tctacttgtg atacatcact actgacacgc gttgttttaa aagatcccca
    13861 agaactgtct ttttgccatt taagcccgtt gatcgtcaac acttcatttg gatcgatagt
    13921 gccgttgtcg agaccgattg ctgctgtaat cattttaaac gtagatccag gagcataacc
    13981 tgtcgcaaat cggctgatga atggatgttc aggattttct tcataagctt tgtaatcttc
    14041 ttgtgagatc ccgtttgtca ttttgtttgg atcatagctt ggagagctag caagcgcaag
    14101 aagatcaccg gtttttggcg ttgtcgcaac agttgatgca gcttttcctc ctagactgtc
    14161 aaaagctatt ttttgtgcct tcgcatcgat tgtcaatttg atatctttgc cattttgaac
    14221 ttcatgttcg atcagaactt ttttctctac accgtctgca tctgtaatgc ttaatttccc
    14281 acctgttgtc ccacgaagat ccttatcaaa agccatctcc aaacctgagc gaccgatttt
    14341 tccattactg cttaattctg gattcttatc aatatcttct gctgtgatat ctcccacgta
    14401 accaatcagc tgagcagctg cttcacccaa aggataatat ctgccgtcta cttcttgaat
    14461 ggtagctcca gctggaagtt ctggcgttgc tccatcaatg attttcaatg ggacaaagta
    14521 atcgggttgt acccagcttt gtgaaatcgc ctgattgata gcatcttctg ttaagtcgaa
    14581 ggaggaagca atcgctttga tattggctgt tttttcgcct ccatctccaa gtttacttgg
    14641 aacgactcct aattgtttta gtttgcctgt tgttgctaat ggttcaccat ttcgatctat
    14701 aatattccct cttgctgctt cttgtgtggt caggcttact ttgtcatttc cttccatttc
    14761 tggaaaaacc aagttgggtt gccagttgat cgtggtttga ccatcatttc tgtctaatgt
    14821 tcctttataa gaaagatctt tcaattcacc taatgaggta ttcatctttg ctttatatga
    14881 aaaactgtaa gtagaatcgt cttttttatc tacttttaga ttcgatatct gaagtccttt
    14941 gacatcagca gcaccgtata tattctggta tttatctaag atctcttttt cagataatgc
    15001 acttttattt gccgcctttt ttgatgtcat ttctgcagct ttgttataat ctcccttgtt
    15061 caaagcttgg acaaattgct caactgtctt ttctccagct tctactgctt gggtttcttg
    15121 atagtgctgg tagtaaaaat aaccgccacc cgcagctgct attaagatca ctgcgccggc
    15181 aatataagcg cctgttcgat ttttgccgtg cttgtcactt cttttcattt tttcctcctt
    15241 ctcttgcttg tcattccttt atttcactat ttatacctgt ttattctaac atatgtcttt
    15301 gaggaaatcc ataccacaat ccagaagcac actttctgga aggttcgttt ggatactacc
    15361 aagtaatttc ccaaccgctt tgggtagctt gaatattgaa gttacgtctt tcagctgctg
    15421 agagatagct ttgatcactt gctgctgcct tctgatcctc ccgaagtctc cttctttgtc
    15481 ttcccgaaat cgagcatact ggagtaaagt attaccatcc atcacttgct ctcctttgtt
    15541 tatatatacg ccatctaaat ctagagattt ttctgcatcg atcttgactc caccaggaaa
    15601 cagttcatta acgcaatcga taaaatcttg aaatgtgata cttgcataat agggagcttc
    15661 aaatttgaaa ttttccttta atgtttgatt taataaatca actcccccat aagagtaagc
    15721 tgcatttatc ttattcattc cgtaacctgg aatatcgaca tatgaatctc tcatgataga
    15781 gatcagtttt gcttgttgtg ttttctggtt gtattgtgca accagaagtg aatccgagcg
    15841 acctccacca atcgatcttt tttcaccgca tctcctcctc acacagcaat ccacttgtca
    15901 ggtgaggagc gagtttgtct catcaaataa gtcagtcaca aaaatataaa gaaaaggtca
    15961 gaaacctttt cgaacaagaa ttctgaccta gcatcatctc atcgtccgag ttttagcact
    16021 atacaacgta aagaaaacat tcttagctat tggaaaaagc cttaatccaa cagtttctgt
    16081 tttacccatt ggcgactttc gacgtttctg ggcaacagcc tatgtttgta taggagcctc
    16141 acctaacaag gttattacta tattctattt acgagttcat gatagacttt tcctaatgat
    16201 taggcaatgg aatttgaaat gaaatagtga aatttaacaa tctttaatat tttttagaaa
    16261 aaaataacaa ataagttgaa agaatcccgt tgcaaattct ttcagttgca ccaggattct
    16321 ttgataattt tttagtttta tgtgtttttt tatatgtttt ttcacttttc ggaataaata
    16381 tttatttgtt aaagtaatta aacaatccgc taatcgtttg atctggcatt tctatttcct
    16441 taccatctaa agtaacagta gtaacgacaa aatggtcttg caatggcgga acttctaagt
    16501 actgcccttg cagaaaatca ttcactgttt catattcttt tttcatttct tttgaatctg
    16561 tcgatggttt atagcttatt tttaacataa ctagtgctcc tttttattcg ggacgtgcaa
    16621 tcgtgaaaat ttctcctatt gctgcataat catttcctgc caaacggctt acagcattca
    16681 attttcttgg atcgatcctt cctgtcttat catcatagac tgtttcattt aaatgatatt
    16741 tctgtacttc tagcaaaaat aaatcagctg ttactttatt tttattccgt atctcgacat
    16801 gttcatataa ggatgtttca aaacgaactt ttgcttctgt caatgctggt actgaaatga
    16861 ttactgaatc agttaaagtc aagtcagtca ggtacagttc gctttcctca ttaggcagat
    16921 tggctgctgt tttatttact tcttctacgt tgtcctcatc aaggatatgg ataacagctt
    16981 ctcttgtctc aagaatattc tttgctgtgt cttttactgc atcttgtttt ctctggatcg
    17041 ccaaggataa gatgggtcga ttcgaactga cgatattgaa gtaactgaag ggtgcgatat
    17101 tcactatatc ttttgctgat ttagtcgtta ctactgctac tggtctaggg atgactgaac
    17161 caatcagcaa cttgtaattt tcacgttctg tcaattctga aggactccgt tcaaacatgg
    17221 tttcgccttc tttctataaa attcgttaaa aagcagatct tgaagacaaa atgaaaagta
    17281 atgctttttt catcttctta gaatctgctt taaactatct atcaattttt cttttttgtc
    17341 aagaatctgt gccgtgcgtg ttttttagtt atttgcttta cttgcggctt cgacatatct
    17401 tttagtgatc aattgcggac gggtgataat agatccaact acgactgaaa aagcacctaa
    17461 ttcatatgct ttctctactt gttcaggaga gtcagtatgt ccttccataa ttactgggat
    17521 atcgacttgt tctatgattt gattcaataa atcaaaatca ggtgtctgcg tctttcgtga
    17581 atattctgta tagcctgcta aagtcgtaga caaaagatca aaaccatctt cttgcgcttg
    17641 aagcgcttcc tcaaaagtcg aaatatctgc catagctaac cgaccgtgtt cgtgaatcat
    17701 ttggacaagt tcagcagttg ttttttctgt cggacgttta cgagaagttg catccagtgc
    17761 aatgatttct gcttgcgtct ccaaaagttc ttccacttct ttttctgtcg cagtaataaa
    17821 cacttctgac ccatcgtaat ctcttttgat aatccctatt accggtaaat caacgattcg
    17881 cttgatttca ttgatatctt ctgtcgtatt tgctcgaata ccaactgctc cgccttcttt
    17941 tgcagccaaa gccattctcc ccataataaa agaactgtgt agcggctcgt tttccaaagc
    18001 ttgacaagaa acgacgactc cgcctttgat ttgttccagt gtatccacaa tatctcctcc
    18061 agtaatgtta tataaaaata cagcttcata taaaaatgta acccttttct attcaggaga
    18121 caataatgag ctatttcttt cagcagacct ttcttactaa aagaaaatta cttcaaattc
    18181 ttcgtatacg accagcttct cttctgtaaa ttctatgttc aacgcttctt tataagcatg
    18241 tttaaaaaac tcagcatgga ctttccgcca ataagctaat gtccgatccc cttctccttc
    18301 tttccaagca tgctctttcg tgacttcact aaaaggcaag atggtcacat ttatattttt
    18361 gatgatacaa actggttcat tttttccatt caggaccacg tctaattgac caacttttgg
    18421 taaaggctca ttctcttgtt tatacagatc gtaaccactt gatgtaccag tctttatctt
    18481 ttttacaact agttcgctca actcgtctgc cattttttct gtatccccaa atgaaaagaa
    18541 acctaatttt tctgattgat aactaggata tttttcttgg aactttttga catattcttc
    18601 tacttgctga tacataacat ccaccccttt gctttttata atgaaaaaac catccagata
    18661 ctagtataaa caattatctg gatggtgagc ataatgaatt attgaatatt caagacacgc
    18721 agactatctt caacgatttg ttttggtgtt aaatgataac gttcataaag ctgccctaca
    18781 ggaacgctat ccgtgaattc tttctctgca ccaaaattta atacgttcat tgaagaatca
    18841 ccataataac gactgatatt ttcgccaaat cctcctgaca aactaccatc ttctaatgtg
    18901 atgactaatt cgtgtgtttc ttttaattta tctaatgttt ctacgtcatt ttctgtgatc
    18961 gttcctggat tgatcaacgt tgcttcgatt cctttttttc taaaagcttt tactgtttct
    19021 tttcctaatt caagaaaacc gcctaaagct aaaattgcta cttttcctcc attatttact
    19081 gtttgatagg ctggaatact ataatcattt gcgatagctg taccatgttc tacaccatgt
    19141 gtaggaattc ggattgctac aggctgcgct gtttgttcga acgcccaatc tagcatagag
    19201 atcatatcct cttttgttgc tggagcaaga tatttgatgt tcgggatact tgataagtaa
    19261 ggaatgtcaa atgttccttg gtgtgttcgg tcactagctg agatcgttcc gccaccgact
    19321 aaaataatca ctggattctc gttgatcgct aaatcatgtg ataattgatc atatgcccgt
    19381 tgcaagaaag tacttgattg gaagacgact ggacgtactc cctgagaagc caaagcagaa
    19441 gcgaaagtga tagagtgctg ttcagcgatc cccacgtcaa aataatgatc tggatgtttt
    19501 tcttggaatg ttttcagtcc aaaggcgcct ggtatcgctg cattgactgc ggcaatagga
    19561 gctgtacttg tttgcatttt cttatccaaa taatccatga tgatcatatt aaatgtttct
    19621 ccagaagtta cttgctttgc ctccccggtg gacagatcaa atggtacatg ccaatgatat
    19681 ttcattttat tatcgattgc cggctgataa ccgcgacctt tttccgtatg gacgtgaagt
    19741 acaatcggat gatcaatatc ttttacttct tcaaataaac ggatcaccgt ttccagatcg
    19801 tttccattat ccacgtaacg ataatcaaat cccattgctt taaataggtt attgctgctt
    19861 ttaccgttgg tttgacgaag ctcagctaag tttttatata aactgccatg attctcatca
    19921 atagacatct cattatcgtt tactaatacg attagattgg attgtaaaac accaccattg
    19981 ttcaatcctt caaaagctaa gccaccactt agggagccgt caccgataaa tgctaccaca
    20041 tttcctgatt ctttcttcag atctctcgct ttagctaaac ctgttgctaa gctgatagat
    20101 gtagatgtgt gccccactgt aaaatagtca tgtttacttt catgttggtt ggaatatccg
    20161 ctcacttcac ggtaatgtcc tttttcaaaa ccattttttc gaccagttaa aagcttatga
    20221 ccataagact gatgggaaac atcccaaacg attttatcct ttggtgaatc aaatacataa
    20281 tgaaacgcaa tcgttaattc tactacacct agattcggac caacgtgccc acctacatcg
    20341 ctgtcctttt gcaagatttt ttggcgcatc tcttctgcca actgtttcat ttcctcaaca
    20401 gataattttt tgacatctgc ggggctattg attgcatcca atacatgtaa tactgtactc
    20461 ataatacatt ctctcctccg tactatcttc ttttaatgaa aatagatttg ttacacttta
    20521 tctattctac tacttagagt tgactctaag tcaatagcat tttaaaaaaa tttcagagaa
    20581 agcttgttat ataagtagat cttcgcacga atcaggactc aaataaaaac cttctacaga
    20641 caattaaaaa gctttgtaga aggtctccta attaaggtct catcaagaaa tatgtttttt
    20701 taataggtga agttcctgag caatatgata caaatggatg tttgcacctt ttaatgagat
    20761 tggatagatc tttgtctttt cagtttctaa tccattttga tagctagcag catcgcacaa
    20821 aaccactctt tttttcgcac atagacattc atcaggcaat tcttctaatg aacgaaataa
    20881 aataggattt atttcagcga tgccttcttc cgcatacaaa tgaaattggg ttcgataaaa
    20941 aaattgtttg actgaacttt ctgaaacaac aaaaatttct atttcctgtc tccccgcttg
    21001 ttcactgttg atcaaagaaa gacttttgac gaattttcga atgaaatttt cattccatct
    21061 tagttggatt tgatttttct ttttccactc ttccaatatt tctacaattt ttccgtacag
    21121 aagttgttct ttttctgata gaagatagat cctttccggt aaaaatactt gtccatctgc
    21181 ccacaacgta cggacaaatt gtaaaaagga ttgcttgaaa ataaaatttt ctgcatcgtc
    21241 gatttcagcg atactaataa tctgtaaaat caattcattc agtgataggt cattgagaac
    21301 aaaattttta taaacaactt cgaaatcttt tcttaacagc tccatgttct cattggtata
    21361 atttctactg ttgaacaaag aaaaaatata atagacatct tcttcttgta agtctagaat
    21421 tcctttttgc tcttccaatc cttgacagac taattgaaat aacggcttcg tttctgcgct
    21481 tttcttatct tcttctttca gtccaagggg aaatgccttt cttccgattg cgatctctat
    21541 tcctcgtatg ataaaggact tttcatcttc cgaatatctt cttttaaaaa aatgagtctc
    21601 tacataatca atcaactcgt tacaagcttc ttctacatac ggatttttat tttcatagcc
    21661 ttcccaattg acataacgta ctaaagctag caagatgttc cgcgagtcaa attctgggat
    21721 aatgatttct ttatttttca aataatcatt ttctttaaaa aaatccaata cgattttttt
    21781 gattgtatat actttgctca aagaaataaa ttcaagatca gccagttctg tactcgtgaa
    21841 tataccatta aaataataac ttaaaaactt taaaaaataa gattgaccgt acagaaactg
    21901 tgtgagctca gaaagagcaa taccatgttt gaatacgagt ttatacttat gcttctctct
    21961 tacttgttct tttatacaat attctagaca ctcggctaga ctttctagat cgtgaaggat
    22021 cgttggtgta gtcaccctta gagaaatagc tgtttgttcg atgtctattt cttggaattc
    22081 aaataattgt tcacacagat acacttttct aaatatattt cgctcgatgt aattttccag
    22141 cattcctgat acacgcctcc agtttttctt atgattttat ttaatcatat ctgtaaatcg
    22201 tatttttgtt tcctttttat ttagaaaagc cctttcaaaa accaataaaa aaagaaactg
    22261 ggacaaaagt caaacaagct cacaatttca gcctcattgt aggtagcttt gagccgtttg
    22321 gacttttacc ccagcctctt tcaagaatgg ttattcaaag atgtcagcgt ctagttcttt
    22381 gactacatct ttcaacaatt ggataccagc tgcgctgtta ccaaatggat ctagtgccgg
    22441 gctgaagaca cctatgccgt aacgatttgg cacagctgcc atcaacccgc cgcctacacc
    22501 gctttttgca ggtacaccaa catggacgga aaactctcct gattcatcat acaaaccagc
    22561 agttgtcata attgatttga cgattgtagc actttcttca gtaatgattt gtttgccatt
    22621 ccaaggagca attcctttat ttgccagcac agcagctaat tttgctatgc ctgtagcggt
    22681 gacattgagg gagcattgtc tgaaataagc atcgagtatc tccggtacgt ctccttcgat
    22741 catttgatta cctttcatat agtaagcaag agagcgattg atatcacctg ttcttgattc
    22801 agaatgatag atttcttcat tcaatgtgat attaggatca tcacagatct ctttcataaa
    22861 tgacaagatt cgctcaaatt tttcatctgc atctttaccg gcaatcaacg aggttgttgc
    22921 aatcgctcct gcattaacaa aaggattcat tggatgtttg cgatgattga tttccatatt
    22981 catgatagaa ttgaaggcaa aaccggttgg ttccgtgttg attgtttgaa agactttttc
    23041 tattccgttg tctttgattg ctaataacaa tacgggaact tttgacatgc tttcgatggc
    23101 aaagcgcaca tcggcgtctc ctccctcaat cagttgtttt gtatccaaat cataaatcgc
    23161 catacctaat tgtttgggat ccacttcagc taatgctgga atgtaatccg ccacttgtcc
    23221 tgtttgataa tagtggaaat tttttccaat caattgttct aattctttta cttccatttg
    23281 aataaccagc tttcattttt tatttttctg catgctggaa tttatgacgg catgcgtaga
    23341 tcgtaaatgg aataactaag acgataagat aagaaacaat cagaatcgtt tcataaatcc
    23401 catgctgtcc agctgcgata ctagcaggtg gaacaaatga gatacaaaaa gcaaaaagtg
    23461 aagtcaaaag acctaaacaa gcaacgatta cttttacaac ttttccgcct ggaacctgat
    23521 aggctctttc aagactgtca tctttaaaaa ccagcttcaa atagcccgcg aaaaacataa
    23581 agtacaacat caggtagatt acaacagtca atgacatcgc tgcaagaaat gaaagattat
    23641 tccccccgcc gcttaatgta aagacggctg cccagattgt tgcaacgatc ccatttgcga
    23701 tcatcaaatg agcaggaaca ccgtgtgtgt tttcttttgc aaaatattca ggaagtaatc
    23761 cttcttctgc tgctacgtga agtgcttttg aaggagaggt tacccaagaa gcaatttctc
    23821 cgatgacacc taaacaaaca agaatcgcaa gaattttcgc aatccatgca agatttggat
    23881 caatgtgtct taataggaat tctaacgatt gaatcacccc tgtattaaga gacaaaccat
    23941 gttgaggtac tgtagtagcg acggtcaatc cgccaaaagt atctaaaatg attgccagaa
    24001 taaccaatac aaacattgct aatggataat cctttttagg gttttccatt tcatttgcat
    24061 gactggcaga tgtttctacg cccatatatg ctaaaataaa ggaaacaaaa acaaccagcg
    24121 taggcaattt cgaaaaatca ggaatcaatg ttttcataga cagtatcgtt tgtagtggag
    24181 cgcctgaagc gacataatgg atccctaagc caaacaagac taatgctggc aacaagatac
    24241 cagctacaaa accgatccga gcaatcaatg aagtgtattt ggttcctttt aactgtgaga
    24301 gtaaaatagc ccagaaaata atcaatagga ttgccaattt cagatattta ttgttttgta
    24361 tagcaccaat acccgttgca taggataatg caccagttaa gaaatacagc atggtcaagt
    24421 agccaactgt tatctcaaac cattggaaaa agattgcggc aaaaccgaat cgttttccca
    24481 atgtgcgact gacccaagta tagacaccgc ctttttccca tcctttcacc gttgccatct
    24541 ctgctgcgca caatgccaca gggataaacc atagcaaacc gcctaataac aagaaaaata
    24601 ctaagctgaa gcctgaggtc gcgaatgtgg gatattcata taatgaaacg accattgaga
    24661 tggtcatagc caaaaagcca aagaacgtta atttttttgc aggaattttc gttttgcttt
    24721 gttgcatgaa tcttcctctt ttctatttga atttgtttca attgagtttg ttgccaaaga
    24781 agaaaaagtc caatccttct tcttgttctt cttttgtagt agtgatcgtt gtaaagtgca
    24841 tcgccgattt taaaatcact gttgtcagca cataggcata cacggcagta atgatgacac
    24901 caatcacttg aatccctaag aagtaccagc tgcttggatt cgttagtaaa tggctgttag
    24961 atgcaaagat ccctatcaga atcgtacctg tgaatccgcc catgccatga acaccccaca
    25021 catcaagtgc atcatcccat tgtttctttt tacgaaaatc aacagcagca tgacagacga
    25081 tacccgcaat gatcccaatc agcatggcac tttttgcttc tacataaccg gcacaaggcg
    25141 taatggctgc caatccagca acggatcctg ttagtacgtc gacaaaatca aagccatttc
    25201 cttttacttt tgcaatgatc agccaagtaa tcatcgcaaa tgcaagagcg atgaatgttg
    25261 aaccaaatgc attgactgct tgttcatctg ctcgaagtgc accaccggaa ttaaaaccga
    25321 accagccaaa ccaaagcagt cctgtaccga tagcagctgc cataagactg ctatgctgac
    25381 ttctttctcc taaaggaatc tttctttgac caagtgtgag gatacatgct aaagagccga
    25441 atccagctgt cgtgtggatg actgctccac cagcgaaatc tctaaatccc atctgatcca
    25501 aaaatccgcc accccatatc cagtggcaaa cagggaaata aatcagcaga ttccaaaaaa
    25561 taacaagtat aatatagcct tttaaattca atctccctgc aaaagctcct gtcatcaaag
    25621 gaacggtaat cacgataaac atcagttggt aaagaaagaa cattaaaaat ggaatcgttg
    25681 caccatgaaa catgttgggg aagcttgtaa catgtctcat caaaaagaaa tctgccgggt
    25741 ttccaataac accgccgata tcccgtccaa aggccaatcc gaatccacca aatacccaca
    25801 taatcgttgt tatcccaacg gagagaaaag attgagacat gatcgttagt atattattct
    25861 tccgtgctaa tccgccgtaa aaaaaagcta gaccaggagt catcaggcaa accattgctg
    25921 tacataaaat catgaatgct gtatctcctg tattgatagg taatgtattc atttttttcg
    25981 cctcctttct acgattacga gtataaaaga aggtgtagtt gtttttttct tctgtttttt
    26041 tgaattaata cttgcattta taaaagacag acaattaata aaagcttgat gtgttgtgct
    26101 ctttttcgtt tttcacacaa ataaagacaa aaaataaacg gtcttctttt tatagaaaac
    26161 cgtttatttt cgtctttttt tatttttaaa gatatttttt cataaggaat aaagaatact
    26221 tcatataaaa tatataaaaa agaaccgcag cgagtgtcgc tacggttctc aaatttgttc
    26281 ttcatttcaa cataagtttt tcttcaattt gcttataatt tacgtgcaaa gaatgaaacg
    26341 actaatacta aaatgattgc accgatcaat gatggaatga tagccattcc tgcaattgtt
    26401 ggtccccaag ttcctagtaa agcttgtcca attgctgaac ctactaaacc agcaatgatg
    26461 tttgcgatga tccccattga tgatccttta ttcgtgattg ctcctgcaat tgctccaatg
    26521 ataccgccga cgattaatgc ccaaataaat cccattttaa attcctccta actgacttct
    26581 tacttcttat tgtacacgtg gttcgttatt ttctttgact ttttgtgcac ctttgcctac
    26641 agcagatttt gctttatctg tttggcgtga agcaaattgt cctgtggatt ttgctgcttc
    26701 tgttactttg tcttgtactg tttcttgatc tttttggtat tcttcttgtg ttttgatgtc
    26761 tgcaacattc acattcactt cgataacatc taaatgtgtc atattgttta cttcagtact
    26821 gatcaattct ttgatttggt tgtaaatatc ttcgatgtct ttaccgtatt ctacgatcac
    26881 atctagatcc acagctactt gtttcttacc tacttctgta ttgatacctg ctgttacgtt
    26941 atctgtgttg actaattttt cagccatatt tgagaaaaat ccgccatcta atgtcaatag
    27001 accatctaca tctttcaatg cataaccgat gattttttgg atgactttgt cttcataagt
    27061 caattcacca ttcatcatgc ggttttctcc tttttcattt gccaaaactg atccatttgt
    27121 tgtattcatg tttttgtttt ccatctttgt ttcctcctat gatttaaaaa attgatcaac
    27181 tattcctgac tgtttcaaat aaaaaccgat tcctgcgcca attgctgtca tgattatgat
    27241 caacaatgtc ttgaaaaatc caatcgttaa ccataaaaca gctagcagta gtccaagacc
    27301 cccaaagata atagggagct tgtatgctga aaatagttct ttcattattt ggccctccta
    27361 ttccactcga gagtgcttgt agtctcttgt atcttcttgt tcttcataac cgctgtatgt
    27421 gactgccact ttgaccgttt cttttgttcc gagtacttta gttacttctt cttcgatatc
    27481 ttgcatcaat acacctgttt tccctactaa tgaagaagtt cgtttcaagt ctccgttgac
    27541 atggatatgg attcgatttt tcgttgaacg tatccgtact ttaggtgaat gaatgaactc
    27601 ttcttcgtgt aaatgggaac gtaccaaccc ttcgatcgct tttttgtcga ttgttagttt
    27661 gccatcttcc cgtttcataa cgaaagttcc tcttgacttt ggatagaaaa gaacgactag
    27721 caagatgata atagcaagaa cggcaaatac tacagctgcc cagaaaatat attgttgcat
    27781 gtagtaattc gttaaagtaa agaagcgaaa tcgttccaat tgttcaggca taatatacgg
    27841 cgcattgatc aacgcaatcg ctagaaatac tgaaagtagc agtaaactca tgataacacc
    27901 gattattttt aaccccttat tcattttcca cctcctataa acttattttt accctgtaaa
    27961 taactctacc gacaatcaca gtatagatag cgaacagtta gcatagcatc agtaaataaa
    28021 gcgctaccaa acattgctgg atcataacgg cgttttattg ccagtctgat actgaaataa
    28081 caattgctta cttattctct atttactttt gattgctggc tatacttaaa ggatattatt
    28141 caagattaaa aattgcaaag attatgctca gttattatta caagattcta tttatt
//
LOCUS       DAXLPQ010000033        27519 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.033, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000033 DAXLPQ010000000
VERSION     DAXLPQ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.033"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..660
                     /locus_tag="ACF3UO_001708"
     CDS             <1..660
                     /locus_tag="ACF3UO_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3657711.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
     gene            822..1010
                     /locus_tag="ACF3UO_001709"
                     /pseudo
     CDS             822..1010
                     /locus_tag="ACF3UO_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            1287..3347
                     /locus_tag="ACF3UO_001710"
     CDS             1287..3347
                     /locus_tag="ACF3UO_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFD3657712.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            3430..3999
                     /locus_tag="ACF3UO_001711"
     CDS             3430..3999
                     /locus_tag="ACF3UO_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3657713.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4174..4980)
                     /locus_tag="ACF3UO_001712"
     CDS             complement(4174..4980)
                     /locus_tag="ACF3UO_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657714.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5119..6633
                     /locus_tag="ACF3UO_001713"
     CDS             5119..6633
                     /locus_tag="ACF3UO_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFD3657715.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7036..8019)
                     /locus_tag="ACF3UO_001714"
     CDS             complement(7036..8019)
                     /locus_tag="ACF3UO_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFD3657716.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8024..8671)
                     /locus_tag="ACF3UO_001715"
     CDS             complement(8024..8671)
                     /locus_tag="ACF3UO_001715"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFD3657717.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(8756..9388)
                     /locus_tag="ACF3UO_001716"
     CDS             complement(8756..9388)
                     /locus_tag="ACF3UO_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3657718.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(9404..9955)
                     /gene="coaC"
                     /locus_tag="ACF3UO_001717"
     CDS             complement(9404..9955)
                     /gene="coaC"
                     /locus_tag="ACF3UO_001717"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFD3657719.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(9952..10689)
                     /locus_tag="ACF3UO_001718"
     CDS             complement(9952..10689)
                     /locus_tag="ACF3UO_001718"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFD3657720.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(10686..11675)
                     /locus_tag="ACF3UO_001719"
     CDS             complement(10686..11675)
                     /locus_tag="ACF3UO_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFD3657721.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            11933..12475
                     /locus_tag="ACF3UO_001720"
     CDS             11933..12475
                     /locus_tag="ACF3UO_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD3657722.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            12492..13577
                     /locus_tag="ACF3UO_001721"
     CDS             12492..13577
                     /locus_tag="ACF3UO_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657723.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            13589..14395
                     /locus_tag="ACF3UO_001722"
     CDS             13589..14395
                     /locus_tag="ACF3UO_001722"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657724.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            14396..15223
                     /locus_tag="ACF3UO_001723"
     CDS             14396..15223
                     /locus_tag="ACF3UO_001723"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657725.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15220..16293
                     /locus_tag="ACF3UO_001724"
     CDS             15220..16293
                     /locus_tag="ACF3UO_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3657726.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            16721..19417
                     /locus_tag="ACF3UO_001725"
     CDS             16721..19417
                     /locus_tag="ACF3UO_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3657727.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            19482..19982
                     /locus_tag="ACF3UO_001726"
     CDS             19482..19982
                     /locus_tag="ACF3UO_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3657728.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            19994..20488
                     /locus_tag="ACF3UO_001727"
     CDS             19994..20488
                     /locus_tag="ACF3UO_001727"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3657729.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            20509..21318
                     /locus_tag="ACF3UO_001728"
     CDS             20509..21318
                     /locus_tag="ACF3UO_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3657730.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            21315..22136
                     /locus_tag="ACF3UO_001729"
     CDS             21315..22136
                     /locus_tag="ACF3UO_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3657731.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22187..24286
                     /locus_tag="ACF3UO_001730"
     CDS             22187..24286
                     /locus_tag="ACF3UO_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFD3657732.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            24283..25401
                     /locus_tag="ACF3UO_001731"
     CDS             24283..25401
                     /locus_tag="ACF3UO_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFD3657733.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            25440..26318
                     /locus_tag="ACF3UO_001732"
     CDS             25440..26318
                     /locus_tag="ACF3UO_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3657734.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            26464..26661
                     /locus_tag="ACF3UO_001733"
     CDS             26464..26661
                     /locus_tag="ACF3UO_001733"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFD3657735.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            26645..26875
                     /locus_tag="ACF3UO_001734"
     CDS             26645..26875
                     /locus_tag="ACF3UO_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657736.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            27120..27311
                     /locus_tag="ACF3UO_001735"
     CDS             27120..27311
                     /locus_tag="ACF3UO_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657737.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         8784 a         4732 c         5745 g         8258 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttctg atggacaaaa aattgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattgtg gacataaaga cggcaagaaa
      541 tctctcgaaa ttcgagaatg gacttgccct atttgtcata ctcatcatga ccgagatatc
      601 aacgctagta tcaatatcct gaccgaaggt ctaaggctac actctatggg attggcttag
      661 atcaaataaa caagaaccgt aggaactacg gggatagctt ggtaaataag aggcacctct
      721 gttagtaaag taatacgcta tcaagtatgc tctcttccca agaagctccc acttcaagcg
      781 taagaaaccg ttaggtttag ctaagtggtg agtagttcac aaattacaat attgtgattg
      841 agagtcgaat cacttctcgt acgaatattt atttatctga ttgtttactt gaaaaattta
      901 ataaagaaca gataatttgg aaaaatccac cgactccaga tgactgggaa tattttggaa
      961 ataccatcat cagagaaaaa aatagacatt taactgaaaa aatcagctag tatttatgga
     1021 tggcagcttt gtctcacata tttattagct gatttatgtt tttttcaaag aaaaggtaac
     1081 tagatataac tagatataac tagatatatt acttaacaaa attaaaaagt acataagtta
     1141 ttattccgat tttcttgaaa caataaaaaa tcaaaaaaaa tactctccta atagtccatc
     1201 ttcttttgat tttatttata taatgaaatc atcttatgaa aattactact tcatgtttag
     1261 acaagagtag ggaggactaa gaataaatgt gttcaaaaag acgttcaaaa caactaaata
     1321 aacacgcttg tcgtttagat aaggaacggt cgtgttctga aaaacactac gttaagttta
     1381 tgatgcgcac gatgctgatc agtttatctg taggtgtcta tatgcatgta cccgttcagg
     1441 caacgacaca aaccatcaag gtcgtacgta cctctgtttc tgagaccact gattccccta
     1501 tcactattac tcatactttc actgatgcaa atggaaaaca gctacttcct gcattgactt
     1561 cctataataa agtcagttat cctccaacga taaaccacta ctggttaatt cctaacaaaa
     1621 cattatggac atcggaaacc ggaagcagtg tgccgctttc tatcttttcc gatatgactg
     1681 atcctacaaa aggtgatcag ttaaaacaga tcactgatat tttgaatcat gctttgacag
     1741 atataaagga cggtggaagc gcacaagttt cttatgtata tgaaaaagat tattcacagt
     1801 ttgaaagaaa gaaaatcgat gttctggcag ggacaaaagt ttcgatatct gatctggtag
     1861 aaaggctgaa gaacgcagat ggaacacaag gagatatgtc caaagtaatt tcaaacaatg
     1921 ggaatatcgt ggatacgact aatacaggaa catctactat ttccttgtcc tattttgatc
     1981 caattgcttt aaaaacaatg actgcatctg ctgtgatcca tgttcgtgct gatcaaacag
     2041 ctatcaaagg aaaagatctt cacttaagaa caggagagag ttacgcccct aaagatcttg
     2101 ttgaatatgt aacaaaaagc gatggaactt caggaaataa agaagaaatc aaaatgaacg
     2161 ggacagtaga tactacaact ccgggagaat atcccgttgt attaacttat atagactcga
     2221 aaacatcaaa tgtggcagaa acaacagctg tagtttatgt agaagcatct gctgcttcat
     2281 cgactgtcat cactcatttt atagatagtc aaacaaataa agaacttcaa gcagaaacac
     2341 atatgagtag tgtaaatcgt attcctgatt tgcgcctacc tgctgaattt tctgatcgag
     2401 tgccaaatat agatttatcg acttatgaac aaaatgggaa agtcacttct atttctgatt
     2461 ggatgcaagc aaacggatta gacagaaaaa gtcactggtc ggagatcctt gaagtacttc
     2521 actcagaact gatgaataat aggaagcaat caggagggga aattaccttt acttatgttt
     2581 atataccaga caatcgttca ttagaaggtc atgatcttat tgttcatcca aacgaaaaaa
     2641 taaacaaaga agagttgatc caatcagcaa caaattcctt aggtaaaccc gtaccgttaa
     2701 aggatgtatc ggttacaatc aatgaagtac cattggagga tggttatttg accaaacaaa
     2761 caggtgattt tacgattatg tatagttatc atgacccgta ttcactccaa gaactccatg
     2821 ctcagtcact attacatgtt ttaccattaa acaaacagat agatcaaaaa gaacaaaaaa
     2881 gacaagaaga aagcttgtca gaaaaaaaac aacaaatggc ccatgcagtt tctccaacag
     2941 ggaaagtaaa acaaacaaga agcctagagt tagcaagaat atctagaaaa atctcagaat
     3001 ctaataaaac gataaggcaa gaagctcatt tggccccaca agtttctgga ttggaaaatg
     3061 aaattttaga gcctaaaata aaacaacaat cagaaaaaga atttgttgct aaacagtcgg
     3121 aagatcagaa ggaatcagat gaccagaagg aaacgaagaa aaaacgcttg tcaactattg
     3181 attccaccga tgagcatctg cagccgcaag taccacttcc tagtccggga acacccgcac
     3241 ctggtggagg tattccttct tctgctttag gagatttcat gcgaggtatg gcaggaacat
     3301 gggtatacgc taatcgaaat gaatttgacg cagatgactg gttctgattt atatctctat
     3361 ctgttatagt caaataagta gctgagtcat atgttatttg gcataatgga gacgaggagg
     3421 gatagaaaaa tgttagataa aacgttacct tacgcagaaa tctggatgac aagaccactt
     3481 caacaaaatg ttccaatcac gcctttagcg gaaggttttg aatttcgatt ttatcaaaaa
     3541 gaagatgaat ctgcttgggc ggagattgag acttccgttg gggaatttca aacgacagat
     3601 gaagcacttg agtattttca acaaaacttt gctccttatc ctgaagaact tgaaagaagg
     3661 atgttttttg tagagacaaa aaaaggagaa aaagtagcaa cctgtaccgc ttggcgaaaa
     3721 aaatcaagag agcaagtgta tccggttttt cattggttag cagtgaaacc agattaccaa
     3781 ggaaaagggc tcgcaaaagc attgactgcc agagtcttgc aagaatttcc taccctccat
     3841 acggacggac caatctatct tcacacacag acatggagcc atcaggcgat tgctctttat
     3901 aaaaaaatgg gttttacttt tattgctgaa aatctagacg gcacacctaa tccagattat
     3961 gaaaaagtta tgcaggtttt aagtaaatta gataaataac gaaatggtga aataagtcct
     4021 cagtattggg ataaaaaacg aaatagtcat tcctcatatc ttactttttt gagttaatac
     4081 tatcggataa ctaatggcat gccatacatt caaaaaagaa ggggcagtga caaaagtatt
     4141 gtcactgccc cttctcttgt tttttagcat gttttatcgt ttgatttttt taggaataaa
     4201 attcttgatg aacgtaaatt tttggtaatc gtttcgacta tagaggtaac caaatacact
     4261 gaaaacaact gctccaataa aattaacaaa taaatccttc atagtatcca tgattcccac
     4321 gtctaagtaa ccattttgga tgattgtttt atctgtttta ccatctgcat tttgactttc
     4381 aatgattgtc cgagtgatat ctggaacatg atagacagtg tttccgtctt tacttaactc
     4441 cacactattg atttgctgga tgatcgtatc tttttgcata tcgaattgca gtaatttatc
     4501 tgctgaaaat tccacaaact cccacataac accaactgtc atcgaaaaac agaaggaaac
     4561 aactgctagt aataaaggag tcaagttcat ggtttttgta tttttattga gcaaataaac
     4621 aagggaaaag ccgacacccc cagctaaaaa tccgctgaat gcatgtagaa aagtatccca
     4681 cattgaaaaa tagccataaa aatcacttaa ctctcctaaa actgttgaac taaaaataaa
     4741 agataacaaa atgatttcta gcatatttgg aatctgtatc tttaatatct tttccagaaa
     4801 ataagggatt tcaaataaaa ttaatgtcag taataaaagc attgtatttc cccagtgttg
     4861 gttccagacc tgatccacta gcataataac gacgatgata cgtaataaaa tatagattcc
     4921 gtttgtgatt ctacctgcag tttttgtact gttcgtaaaa aaggttttca aatgattcat
     4981 aaaataactc cttcatgtat atccttaatt atactaagaa gcgtgtgttt accaaagcta
     5041 tatgacttaa agaaaaacag agttgatatt gtgaaaaaaa tcacttaata tagtataagg
     5101 agaaaagggg ggatacaaat gaaaaaatta gttgctggtt tattaacagc cgttgcactt
     5161 cttgctatga gcgcatgcgg cgcagatcag aaaaatacag cgcagacaag ttctagtacg
     5221 aaggaatctg ccgaagtatc atcaggcgct tctgaacaag tatatacaga tccaaaagaa
     5281 atgaaagaat cttatgatgt cgtgattatt ggagctggtg gtgcagggat ggcagcagct
     5341 atcgaagcaa aagatgctgg gttgaatcca gtaattttgg aaaagatgcc tgttgccgga
     5401 ggaaacacat ctaaatcatc aagcggtatg aatgcttcag aaacaaaatt tcaaaaagaa
     5461 gaaggaatca aagactcgaa tgatgccttc tatgaagaaa cgctaaaagg tggtggagga
     5521 acgaatgata aagaaatgct tcgatacttt gtcgatcact ctgctgatgc ggtcgattgg
     5581 ctagatcaaa acggtatcaa actggacaac ttaacgatca ctggagggat gagtgaaaag
     5641 aggacacatc gtccgtctga tggctcggct attggtggat acttagtgga ggggttattg
     5701 aataacgtcc atgagcggga aatccctatt tttgtcaacg cagatgtgac agacattaag
     5761 aaaaatgggg aaacggtcaa tgaagtgact gtacatgttc aaggagaaga accaaaagag
     5821 gtcaccggaa aagcaatcgt agttaccaca ggcggttttg gtgccagcaa agaatttatt
     5881 gaaaaatatc gtcccgattt agctgattat attacgacaa atcaagaagg atcaactgga
     5941 gatggtatca ccatgattga aaaattaggt ggacaaaccg ttgatatgga taaaatacaa
     6001 attcatccaa ctgtgcagca ggatgagggg gtcttgattg gtgaggttgt tcgcggagaa
     6061 ggagcaatct tggtcgatca agaggggaaa agatttgtca atgaaatgga tacaagggat
     6121 aaagtatctg cagcaattac agcattgcct gaaaaatcag cttatttgat ttttgaccaa
     6181 ggcgtgcgtg atcgtgccac agctattgaa ttttatgacc aaaaaggata tgtcacaact
     6241 ggaaagacaa tggaagaatt agcagaaaaa atcgatttac caaaagaaac actagcaaaa
     6301 acagttgatg gatggaatac ggatgttgcg gagaaaaaag atgctcaatt caaccgtgcc
     6361 acagccatgg aacatgactt atcgtctccg aattattatg cgatcaaaat cgcaccagga
     6421 atccattaca cgatgggcgg tgtgaaaatc aatacgaaca ctgaagtatt agataaagaa
     6481 aaccagccaa ttagggggtt atatgctgct ggtgaagtca caggtggctt acatggaaac
     6541 aaccggatcg gtggaaattc agttgcggag atcattattt ttgggcgaca agcgggcata
     6601 caagcagctc gatttgcttc ggaaaatgaa tgaaatagaa cgtaaataaa aagaggttgt
     6661 gaaatcagcg ttttgagcta ataccgaggg tcagctgatt gaacactgtt tagtgaagag
     6721 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta
     6781 tgtttttaac ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6841 gaaaaagagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa
     6901 acggcggaag cagaagaaat tccttcggaa ataagctgaa attcacaaaa atttgaaaag
     6961 caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt
     7021 ttgatcagca tgattttatt cagttatctt caaaatgatt tttccgatgt ttttgtttgc
     7081 ttccatatat tcatgcgctt gtttgactgc gctgaattgg aatgtacggt caatgattgg
     7141 ccgaatcttg ccattttcta gaaaaggccc agctttttgc ataaaagttt gtgcgagctc
     7201 tgctttatac tgatcacttc taggtgtcaa taatgtacca agcagttgga cacgtttccc
     7261 aatcaataca ccaaggtcta tctcaggcac gatggtccca cctagcatac caatcaagac
     7321 ccaacgtcca tcaacggcta tagaagctaa attcttttcc cagtaagaag cgccgatgaa
     7381 atccaaaata acatcgactc cccgaccttc agtgattttt cgtacctctt cttgaaagtc
     7441 ttgtttttta tagttgatca attcatctgc accaagttct ttacaaaagg cgagtttttc
     7501 ttctgatcct gcagtaacga tgattttcgc gtgagaaagc tgtctagcta attggatcgc
     7561 tgctgttccc acaccacttg ctcctgcatg gatcaagaca gtttcgcctt cttgtaattt
     7621 tccaagccag taaagtgttt gataagcagt caaaaaaact tctgagattc cagcagcaga
     7681 aacatagtct agcgtatcag ggagaaggat tgcacgatcg gcaggcatca cagcatattc
     7741 ggcataacca cctagattga ctaatccgta tacttttgtc ccaggagtaa aagtggagat
     7801 atcactttta ttctcaacta cctctccagc tacttcgact cccaaaatag ggtagggagg
     7861 tttcaaagag actgattctc ttttcataat atctgttcga ttgacagctg ctgtatggac
     7921 tttgatcagt aattcgcctt gttttggttt aggaacaggc acttcaattt gttctaatac
     7981 atctacagaa ccaggatgct tgattgaaat ggcacgcatg gatctattcc tcctttgccc
     8041 attcttggaa tgctgtattc aactctttgc taccttcaga aagtactaga gtcgtacgag
     8101 aaatatccgt ttcttccact agagcggcaa gtacagcagc aactgtagag cgagtgatcg
     8161 tttttgatgc cttctcatta ggcttagtta attgaatgga agtaacttct tcatcgttag
     8221 tcaatgtgac tggttgaaga atgacaaaat ctaagttagt tcgtttcagc cattcatctg
     8281 cataatgttt agtaatataa taatctgtca tggactcagg ccattttgct ggttcatctg
     8341 cataaacagc actgaccatc agatagcgag agacatgcgc attttcagct gcgatcactg
     8401 ttttgattgc gccatccaag tctacttgca gaagattctt tccttgagag ccggcagcaa
     8461 aaatcaatac atcgatgcct ttgaatgctt cggtcatttt ttccacggac caagttaaat
     8521 caaaagagac atacgaaaca ttctcttttt ttactaatgt ttgggaagca acatctctca
     8581 cccctgcaaa aatttcatgg gaacttggag ctaaatcttt tatcaggtgt cggccaattt
     8641 gtccgtttgc acctacaaca aaaattttca tttggatcat cctttcgacg tcaaatcttt
     8701 ccattcaata gtaacaccaa aagagaaaaa aatcagagat cggctacgat gactatcagt
     8761 tagtaagaga agggtgcttg aagtatctta acaagacatt gcatactgct gcagtcgcaa
     8821 gacctgcgac gattccttca ggtataccac ttgtaaaaat aaccgctaga atagctgaat
     8881 aaacagcatt taaatttgtt ccgatgactt tggcataatc ttgctggaat aaaaagtaga
     8941 tcatattcat cactaaaatc gtattggtca atgaaccgga aagtccagct aagaataaag
     9001 aaacggaatc tgctttttgt ttcattagtt tgcgcagacc tttataaacg aaataaggaa
     9061 ccaccccaat caagatgcga ggaataaacg cgatcagcaa ggctttccag cttccatgtt
     9121 ctgttccgat gactgggata aacggagaaa agacaaaaga caaaggtgtt tggataactg
     9181 tgctacggat catgctgatc agtccaaatg taccgccaag aaaagcacct agtcttggtc
     9241 ctaaaacgat cgaagcaatg attacaggaa tatgcatggt tgttgcattg attggaccga
     9301 tagggataaa acctaaaggc gtaacagcta ataaaatcaa aatagctaaa aacatcgcag
     9361 ttaatgtaaa gttttttgta tttttcataa gtactccttt tttctaagca tttctttcat
     9421 taagagtcag catgacctgt tcgatgatcg tctgaatatc agctaaggca ccttttccaa
     9481 aatctccaca agctaaaaga gattctcttg gttcaatttc ctgatagccg acagatctca
     9541 atgtttccag attacgctga gtgatcgggt tttgatacat attcgtgttc atggcagggg
     9601 caatcaattt tggtgttccc actggaagcg ccattgcgac tgttgaaaga agatcgtctg
     9661 caatgccgtt tgctagcttg ccgataatgt ttgctgtagc aggcgcgatg agaaacaagt
     9721 cagcttgttt tgctagttcg atatgattga ttacctgcgg atttgattct tgcatgacgt
     9781 ctgtatggac tgcgcgcttc gacagagatt gcaaggttaa tggcgtgata aaatgtgtgc
     9841 tgcttttaga cataatcaca tctacctggg cacctaattt gacgaattga cttgtaagat
     9901 cagcgctttt gtaagcagaa atacttccag taacgcctag taagatcttt ttcattttga
     9961 ttcctccagt ctaattttct cagtaatcaa tgcagcaatc tcagatttac tttgagcttc
    10021 ttccactgtt ccatctttag ataagagata gccgtggtgt gtctcgccat ggatttccgt
    10081 caaatcattt gcgaaaataa aatcagtttt gttatttatc agactatttt ttgcgactgc
    10141 cagaagagat tcctttggta catctactaa tagtttgaaa ccaatgattt ttgcttttgg
    10201 ctgccattca cgtagataag aaatgatttt tggtgttttc ttcaaaacga gcacaagatg
    10261 ctcggtgtta gaagagatct ttgaaacagt ggtatctgtc tgttcatttt ccgcaaacca
    10321 attgtccagt tcttcttgcg ttgaagaagt gggtaggttt tttgccagct gttcttctga
    10381 aaaactaaaa gcaggagtaa aatcactgac tgccatactg tggataatcg catcgtagtg
    10441 ttcttttttc gttagttctt ctaattgtaa aaataagtcc agtgcagatt cgatcgtata
    10501 aatcgttata ttggagtgtc ttttcggttt cagtgcttgt ttcgtagtca cgtaatcgat
    10561 tgtggtatcc ggattggcag ctaaataatc agctaatgct tgccctaatc gtcctgtcga
    10621 atgatttgta atagcacgta cttgatcgat tttttcagtc gttcctccag ctgtgattag
    10681 aatcttcatt tatggtcacc tacatttact agtgttcttc cttggtgtgt tccagcaagt
    10741 agtttagatg ctgtttcagg caattgatcc agagtaatct cttggacgac cagttcatct
    10801 gcaatctgca aatccgccat ctgttgccat aaagaaagac gttgatctat tggtacattg
    10861 acagaatcaa ttccaatcaa ctggatgttt cgcagaataa aaggcaagac agtcgcgttt
    10921 agtttgattc ccccagcatt gccacataaa gctactgcac cgttataaga gatcaatgga
    10981 agaagactgc ttagctgctc gccacctact gtgtcgatga catagtcgat ttgctgtttt
    11041 cctaaagctt ttgttgtctc tggcagaaat tcatcaggtc gtacgacttg caaagcacct
    11101 agacttttta gccatgtgac agactcttct tttctggaaa aggcaatgat tgactggaat
    11161 cctagtttat gtaacagggc tatcgctgta ctgcctacac cgccagaagc accagtaacg
    11221 acaacttttt tatcggaggt cataccttga cggattaaag cgttcacaca caacatagca
    11281 gtaaaccctg ctgtaccaag gatcatcgct tgacgcagcg tcatattttt tggtagagga
    11341 actaaccagt ctcctggtac tttttgatat tggctataac cgcctggatg ggtgacgcca
    11401 agcccaaaac cagtagcaag tacaagatct tcttttgaaa aacgtggatt gttactttgg
    11461 acgacagttc cggataaatc aatccctgga gtcatcggat atgttcgtat cacctgacca
    11521 gactcgctca ttgccaatgc atctttataa ttgacatcag aataggcaat ttttaccaag
    11581 acttcatttt cagccaactc agtaaatggc agatcactga ttgctgtatg gaaaacaggt
    11641 tcctttatta cctgaaaaga tcgaaaagcg ttcattcgtg agacactcct tttaaaattt
    11701 tcttttatca taccataaag cctactcttt tattcttgtt cttccgtaaa tttagacaaa
    11761 aattaggtga aaaataaaga atcaaacaac tagaatttat tccaaaagat aaagaaatat
    11821 tcagcaaaaa aaattttaca aatggttgcc tttttcaata aatttcgtat actaatacga
    11881 gtggtagtaa acaggaagtt tactattaga aaacttcgat tcggaggaaa ttatggaaat
    11941 tggtgagaag ttaagaaatt tgcgcatcca aaagaatttg acacaagaag aactaggcga
    12001 acgcacagat ttgtcaaaag ggtatatttc ccagttggaa cgagatttaa gttcaccatc
    12061 aatggaaaca ttcttttcta ttcttgaagt cttaggtgtg actccagaag aattttttca
    12121 tcaagaagca gcgaatctgc aagtggttta ttcaaaagaa gatcatacgg tttatttcga
    12181 tgaagaaaac gggtatgaat tggaatggct cgtggctgat tcgaatgaaa aagaaatgga
    12241 gcctgtcttg ctgacttttg aaggtgcagg agaatataag acgtttgaac cttcattatc
    12301 tgaaacgttt atttttgtat tagaagggga attagagtta agcttaggag agacggtcta
    12361 tgtggcaaaa gcaggacagt cgatctatta tcaagcgaca aaacaacatc aattaaggaa
    12421 tcatctcaaa aaacgaacaa aagtattgat tgttgcaacg caatcatatt tgtaatatag
    12481 ggggtaaaaa cgtggggaaa ccaatcattt catttgatca agtagtgaaa cgctatgatg
    12541 atgaaacagt attaaaaaaa gtaagttttg agatcgaaca aggaaaattt tatacactgc
    12601 ttggtccttc cggctgtggt aaaacaacga tcctacgtat tatagctgga ttcaccgaag
    12661 ctacagaagg ggacatctat tttgaaggga aacggttgaa tgatttgcca gctaataagc
    12721 gacaagtaaa tacagtcttc caagattatg cactttttcc tcatatgaat gtttttgata
    12781 acgttgcttt tggattgaag atcaagaaaa tgtccaaatc agatatcgaa aagaaggtaa
    12841 aagatgcttt gcgtatggtc cagcttcctg gatacgaaaa acgggagatt agtgaaatgt
    12901 ctggtggtca aagacagcgt gtagcgattg cacgagcaat tgtaaatgaa ccgaaagtat
    12961 tgctattaga tgaaccgtta tcggcgcttg atttgaaact acgtacagat atgcagtatg
    13021 aactgcggga tctgcaacaa cgattaggaa tcacgtttat ttttgttact catgaccaag
    13081 aagaagcgtt ggcaatgagt gatgagattt ttgtcatgaa taaagggaaa atcgtccaaa
    13141 gtggtacacc cgtagatatt tatgatgagc caatcaatca tttcgttgct gattttgttg
    13201 gggagagcaa tatcgtggac ggtgtaatga tcgaagataa tctagttgag tttgttggta
    13261 agcaatttga atgtgtcgat ggcgggatgc gtctaaatga accagttgaa gttgttttac
    13321 gcccagagga tttgacgatc acgacaccag ataaaggaaa actagtcgta acggtcgata
    13381 ctcagctgtt tcgtggtgtc cattatgaaa tcatctgtta tgatgaacag caaaatgaat
    13441 ggatggtcca ttcaacgaaa aaagctaaag aaggaagcaa agtaggattg gcctttgagc
    13501 cagaagatat ccatgtcatg cgtttcaacg agtctgaaga agaattcgat gcacgtcttg
    13561 acagctacga agaatagggg ggacaagaat gaaaacaatg cgcaggatct attccgtccc
    13621 ttatattttg tggctcggtt tattcgtgat cgcgcctgta ttaatgatca tttatcaatc
    13681 tttttttgat atgaatgggc aattcacgct gaataattat ctatcttatt ttacgtcggg
    13741 gacatcgctt tctatgacga tcaattctgt atggtatgca tttttgatca cgtttttcac
    13801 gctgatcatc agttacccga ctgcttattt tttaacaaaa ctgaagcaca agcaattatg
    13861 gctgatgctg attattttgc ctacatgggt gaatctgctg cttaaagctt acgcatttat
    13921 tgggattttc agtgtgcacg gcagcgtgaa tcatttcttt gattttatcg ggatcgggcc
    13981 gaaacagata ttattcacag acttcagttt tctgttcgtg gcaacgtata tcgagattcc
    14041 atttatgatt atgccaattt tcaatgcatt ggaagagatg aatccttctt tgatcagtgc
    14101 tagtagagat ttaggcgcga atagctttga gaccttccga cgagtgattt ttccgttatc
    14161 attaaatggt gtgaaaagtg gtgtccaagc agtatttatt ccttctcttt ctttattcat
    14221 gctgactcgt ctgattggcg gaaatcgggt gatcacttta ggaacggcta tcgaacagca
    14281 tttcttggtt acacaaaact gggggatggg ttctacaatc ggtgtgattt taatcattgc
    14341 tatgttcatc gtgatgctcc tgacaggcga gaagaaaaaa ggaggtcgct cataaatgaa
    14401 aaaatttaaa tggtcgtatc tttatttagg gatcgtcttt ttattcttat atgcaccgat
    14461 cttctatctg attttttatt ccttcaatga aggaggaacg atgaacagct ttacaggatt
    14521 tacttgggaa aattatgaag ctgtttttga agatacacgt ttgatcatta tcgtattgaa
    14581 tacgttcatg ctggctttct tatctgcatt gatcgccacg atcatcggga catttggggc
    14641 tatgggaatc tattacacga aaaaacgacg tgcacggaca gcgttgttga gcatgaataa
    14701 catcttatta gtctctcctg atgttattat cggtgctagt ttcttgattt tctttacact
    14761 actaggattc ggattaggtt ttcagagtgt attgctttcc catattgctt tcagcattcc
    14821 aatcgtcgtc ttgatggtct tgccaaaatt gcaggaaatg aacgattcaa tggtcgatgc
    14881 ggctagagac cttggtgcta ataatttcca agtagtcaaa aatatcattt tgccttatct
    14941 ttctccagga atcatagctg gatattttat ggcatttacc tattctcttg atgattttgc
    15001 ggttacattt ttcgtcacag gaaatggctt tacgacgctc tcagtagaga tctattctcg
    15061 tgcaagacaa ggaatcagtt tagaaatcaa tgcgctaagt gcgttagttt tcttgttctc
    15121 catgatattg gtcattggat actactttat tagtaaagaa aaccgtccaa aacggctgaa
    15181 gaaaaacaga agagtacgcg agggggtggc acggctgcga tgaaaaaatt acaatctctg
    15241 tttttaggta ttctcatcat tattgcggtg ctgctgcttg gtgttcgtca acttgaaaaa
    15301 acaagtggca tgagtggagc aaaggtactt accatctata actggggaga ttatatcgat
    15361 cctagtttga tcacgaaatt tgaaaaagaa tatggataca aagtgaatta tgaaacattt
    15421 gattctaatg aagcgatgtt cacaaaaatc cagcaaggtg ggacaaacta cgacatcgct
    15481 ataccaagtg aatatatgat ccaaaaaatg atcaaagaaa aactagtact tccattagat
    15541 cattcgaaga tcaaaggatt aaataatatt gatccacgat ttttagactt ggattttgat
    15601 ccagataatc agtattcgat tccatatttt tggggaactt tagggatcgt atataacgat
    15661 aaattctttg atgcaaatca aattaagcat tgggatgatt tgtggaagcc ggaattaaaa
    15721 gacagtttga tgctgattga cggtgcacga gaagttatgg ggctttcttt gaatagttta
    15781 ggctattctt tgaatagtaa gaatatggca cagctgacag aagcagcaaa taaattgaat
    15841 catttaacac caaatgtcaa agcaatcgtg gcagatgaga tcaaaatgta tatgatcaat
    15901 gaagaagcct ccgtggcagt gacattttct ggcgaagctg ccgatatgat gtgggaaaat
    15961 gaacatttac attatgtgat cccaccagaa ggatccaatc tttggtttga taatatcgtt
    16021 atgccaaaaa ccgtgaaaaa taaagaaggt gcctatgatt tcatcaactt tatgctagaa
    16081 ccggaaaatg cggcacaaaa tgcagagtat attggttatt ctacaccaaa tgaagaagca
    16141 aaagcgttat tgccaaaaga catttcgtcg gacgaacaat tctatccatc tgatgacacg
    16201 atctcccatc ttgaagtcta caaagatcta ggatcgaaat acctaggcat ctataatgac
    16261 ctattcttag aattcaagat gtataggaga taatggcaaa actcagtaag aatggggact
    16321 tatcaacgtt ctaaagagct aaaaatcgtc ctttttctat ctgagttttc caatcttcta
    16381 ccaaaagcgg atgaaacgcc gctttttttg tgttatttta ttttttctac cacgtttttc
    16441 taccagagaa aagtggacaa aaccattgta aaatagggcc cgagacgggc tagtaaatct
    16501 aagattgaaa aagttacaga aggataaagt aattggaaac tatgcaaata tacttaaccc
    16561 ttctgtaatc tattaataaa actaatatat gaatccagtt caatatttgt agctatgaaa
    16621 aaacataaaa atcatattag ataaaaacta aattggtaga taaattattt tgtcagatat
    16681 ctgaggcaaa tattcgacta tttgtgtttc aaagtaaaaa ttggaataca aatatagaat
    16741 agacatattg cagccgatag tttattatgc ttttagacac attaaactgg aggaaaaaat
    16801 gaaaaagagc gctaaagatc gagtttttga tgagctgata cgactaacag ggaatatgtc
    16861 ttctgtcact gccgagaaaa tttcgaagaa tctaggtatc tctcgtcaga atgccagcca
    16921 ttatttgacg agattagtgg aagataaaaa ggtcgagaaa ttaccgggaa agcctgtttt
    16981 gtggaagcct ttagatgaat atgcggttgt agataatacg gagcaaataa acgaagcctt
    17041 tcattctgta gttggtcatg acggaagtct gagagaggtc attcaaaaat gtatagccgc
    17101 tgtcaaatat ccgcctaacg gactcagtgt attaataaat ggagccacgg gtgttggaaa
    17161 aagtttttta gccacaaaaa tttttgaata cgctatccat gagcaaatta ttgaaaaaga
    17221 tgcaccattt gctatcttaa actgtgccga ttatgcggac aatcccgaac tgctttcggc
    17281 aacactgttt ggatacaaga agggggcctt tacgggggct gaaaaggata ccgatggttt
    17341 attggcaacg gccaacaacg gctatctttt tctcgatgag gtccatcgcc tatcgaaaga
    17401 aaatcaagaa aagctctttc tatttattga tactggaaac tatcgtccag tcggtgaaaa
    17461 tgtaaattgg cattctgcta aggttcgttt tattttcgcc acgacggaaa aaggtgaaaa
    17521 ttatttatta gacacctttg atcggcgtat tcaaattagt gttatgttgc caacttttga
    17581 agatcgcccc attcgagaac gattagagct gattcaatta ttttttcaaa atgaagcgga
    17641 tgttttacaa aaagatatta ttgtttcaag agaagccttg tctttaatgt tatctcatcc
    17701 ctttagtggg aatattggta agctgaagaa tatcattaaa atcagttgtg cggatgtgta
    17761 tagtcgaaca caagaagaac cattaacgat tgggaaaaat gagatcttga ttcagttaaa
    17821 tatgctggaa tccgaagtag aaagcttgcc gattgctagt ttattgataa agaaaaatca
    17881 aaagataaaa acggatcgaa tcaaaccgtt tgattatgat tcgattttgg aaaaaattac
    17941 tcagctgata aatgaaggta atttcaatga aaatttttct tcgataaaga atgaagtaca
    18001 gcatttggtg catcacattg ataaggattc ttttttatca atgagtagaa aattgatgat
    18061 tcagatgttt agaaaggtct gggtatccgt tttaggaaaa acgtacggat tgacgacgag
    18121 tggacctgtt gcagaaatta ttagcagatc ctatgtcatt tccccaagct ataagacaga
    18181 cttaaccggg ataaatcgta cattagctgc aaatctacct cggacgactt acttatgtaa
    18241 tcagttcttg gagcatttac caccgctctc agaaaaggac gagaactttc taagactgct
    18301 tattgtcgtg actttatctg attatgtaga tgaatccatc gagctgaagg gcctgttgct
    18361 tgctcacgga gatagtacgg ctagcagcat tcaagcagta gtgaatcaat tatgcggcaa
    18421 ttatgttttt gaagcgttgg atatgccagt agagagtaat gtgtcagaga ttgtcgaatc
    18481 gacaaggaat ttcgtgaaac ggcaagtgaa tacagatagt ctagtgctga tcgtagatat
    18541 gggctcttta aatcaaattt acacacagat caagaacgat ttaaaagggg agttacttct
    18601 tctgaataat ttgacgactt ccattgcact tgatattggc ttgaagatga cgatgaatgc
    18661 gccatttaaa cagattgcgg aggatgcagc agacaagtat tcaatcaatg ttcaatactt
    18721 tgaaggcttt tctcaaagta gcaacattat catttcctgt atgtcgggtt tggggatttc
    18781 ggacaaattg aaagatgttt ttcgtcatca tttatcggat gaatccatcg aagttttcac
    18841 gaaggactac agagaactac gtgaattaat cgaccaaaat gatgaaactt attttgacaa
    18901 gacaaaattg gtcatcacga cttcggatct tccacgttcc ttttcaattc ctaatattaa
    18961 tgtttatgac atcttagacg gtgatggagc agccaatttg gagcatattt tgagtcctga
    19021 aatgaagccg gcagaattta accgcttgat tcaggagcta gtaaaattct tttcgttgga
    19081 aggaattgcg gaccgtttga actttctgaa cccaacgatc gtgatgagtg aagtggaaac
    19141 agtcatttct aaatatgaaa attactatca tttcacttta aatggccgtg taaaactaaa
    19201 tctctatatg catacggcat tgatgatgga acgtttattc ttggctcgga cagaaaaatc
    19261 tgaagaaccg aattatgatt tgaaaccaga tgaagatgaa ttttattatg tttctagaag
    19321 tatttttcaa tcaatggaga tgaaatataa ttttaaagtc aatgcttatg agctttcgct
    19381 gctctatgaa ttattaggac cgtatattca aaaataaagt gtctaaaaaa gtgtctaatc
    19441 tgtttttttt aggttagaca ctttttttaa tgtgaattaa cgtgattaaa ccaatgtttt
    19501 taaaagttgg cacaggaatt gcttatataa aagtgaacag aaagaaagga attaaccata
    19561 tgaagaaaat tctaatagcg actcacggtc acttagcttc aggctttctt agcagtattc
    19621 aattactgac ggggaaggtt caagagatta cggtgattaa tgcttatgtg gatgagtgtg
    19681 attttgaaca ggagttgaat gtatttgtaa accaggtgaa cgagcaggat cagatttttg
    19741 tttttaccga tttatttggc ggaagtgtca atcagaagat taccaaaacc tttttggaga
    19801 aagagattgc tgtaactatt ttgtctggct ttaatctgcc aattctgctc gaaatagtat
    19861 tggcaaccaa ggaattaaca aaggaggata ttcaggaact ggtaaataaa tgccaacagg
    19921 aattaaagat gaccattctt gatgaggtac atgtagtaaa tgaagaggaa gatttttttt
    19981 aggaggaaga aaaatgatta aagcagtgcg aattgatgaa cgattaattc atggacaagt
    20041 agcgatgact tggacaaaga gtctaaattt aaccgggtta gtagtagcaa gcgatgaggc
    20101 ggctaccaac gatattcaaa agatgacatt gaagatggct gcaccatcga atgtcaaagt
    20161 cattattaaa acagttgatg acgcgattca tttgttaaaa gatccgcggg cgaaggacat
    20221 gcgcttgatg gttttagtcc ctaatgtcaa agatgcggta aaagttgcga aagctttccc
    20281 aacggaaatc gaattaatga acgtggggaa tgctgggaaa atgacaccgc catcggaaga
    20341 taagaaaacc ttatcaaagg aagtgatgtt aacgacgtca gaaattcaag acttaaaaga
    20401 attagttgaa ctttatccag ataccgtttt tcagcctaca ccggcgatgg aaaaacgttc
    20461 agctatctct attttgagtg atttttagaa aaaggaagga gaaaaattat gtatgatgca
    20521 tttgtagtcg ctttggccgt ttttattgga gttgctggac atgaaatgtt cgggatgtcc
    20581 atgctgagtc gtccgattgt tgttgctccg ttagcaggag cgttgatggg ggatttgcag
    20641 acggggttga ttgtcggggc gtcactagaa gccatcttta tgggtgtcgt caatatcgga
    20701 atctctagta cggcggagcc ttctttggct gctgggctgg ctacagcgtt cgcaatcaaa
    20761 atgggaggaa acgtggatgc gattattccc attgtctttc cactagcagt attaggatta
    20821 cagttaatga atatgatttt ttcttttgta tgtggaccga tggctgctaa atttttcaaa
    20881 tttgcaaaat ctggtgatca aaaaggaatc atcaatctgc acttctttat gtggtttgtc
    20941 cactatgcgc tttatgctct tattccattc tttgccgttt tatttggagc agatgttgtc
    21001 aaaagcgtct tggataatat tccagaggtc atcatgaacg gattaacagt cgctggaaat
    21061 ctgctgccgg cagttgggat ggcgatgctg ttacggatgc tttggagtaa aaatattgct
    21121 gtgtggtttt tctttggggc cgttgttatg gcgtatctcg agttaccatt gattgcaatt
    21181 gccgcagttg gaacgattat tgcaattgtt atagcccaaa gagatctaca actaaaaaat
    21241 atatctgttc atgcagttca aagcgatgct gctgtaaatg caacgcttga ccaagaagag
    21301 gaggatttct ttcaatgaaa ttagctgatg gaatttctaa agatgagaaa aaattggttc
    21361 ggaagatgtt ttggcgctcg atgactatgt atgcttcggt gaatccggtg acgatgggcg
    21421 gcggtggttt cgcctattct atgatgccct tcattaatca tttctacaaa agtgaagaag
    21481 atcgagctgc ggcgctggaa cgtcatacac agtatttttc gacgaccatt ccttgcgcgt
    21541 cctttgtcat ggggattgcg gcatcgatgg agaaggaaaa ttctgaaaaa gctggttttg
    21601 acgtggaaag tatcaacgcg atcaaaacga gtttgatggg accattggct ggaattggcg
    21661 attcattgtt ctggggagtt tggcgtgtcg ttaccgcggg actagcgatc aacttagcca
    21721 atgccggaaa tattttggca ccaattatct ttttagttat gttcaatata cctaattact
    21781 tgatgcgata ctatggcggc gttttaggct attcattagg ctctaaatat attgaaaagc
    21841 tgtatgcgaa cgggttaatt gaaattctga caaaagctgc tagtatcttg ggtctgatca
    21901 tggtaggtgc aatgacgatc agtatggtca aattcaatac cgttttgagc ttttcaatga
    21961 agggcgaaga actaatgaat gtccaagaaa tcctcgatag tatttttaaa ggaattgtac
    22021 cgttattggt aacattgagc tgtttcaaat tactagataa aaaagtcggc gtcatcaaaa
    22081 ttatttttgg aatggtcgtc ttgggaattt tattgtcatt acttggaatc gcatagtagg
    22141 aagctgcagc tactaggctg cagttttttt agcaaggagg gaaaagatga ctattaatga
    22201 agtaatttat tcacccaaac acccattttt taatgctgag ttaaacgacg gaaatgtgac
    22261 tacttcaaac gaatacagct actatcggaa tattcctgat gtaaagggat tgaccttcga
    22321 tgtaagtaat caaaagacat tagcaaacct tgatgtttgc gggacgattc aaacgttgac
    22381 cttttatcga gaaaatttac taactgagga aaaaccaggt gtttgggtca ataaacagct
    22441 ctctcaaacc aattcgttat ccttaaaggt tgaagtaaac gggattgtct accatttgtc
    22501 agaatcggat catcgtattg aagtcgatgt gattcaagac tgtttgccta gatatattca
    22561 tcattattcg acgtttaagg tcattgtagt atcctttgct cccatactgg ctaataagcg
    22621 tttaagtatg cttgttcaac aggtttacat tgtgaatgaa acacacgaaa gccttcaagt
    22681 ttcagtgaaa gatgtgcctt cgtatcaaga gaagtattcg gatcagcaaa atgtgttgat
    22741 ttctcaaaaa ggaaataagg acacgatcgc acaacaggaa gtggcaagct tcgccattgc
    22801 ttttgtggac ccaaatgctt ttgaagaagt aatgactttt caggaatctg atatcgaaaa
    22861 atggctgaag gaaacattga actattttgc tcagctattt gggcagctgt caatgccaaa
    22921 cgatagagtt gtccatctct atcgtcgtgc actttatcaa agcttttcta gtttcggtat
    22981 gaatcgacag ggacaggtcg tcggcagcaa ttggggcagc tatcctgcta ctaatcgaat
    23041 ttggaataag gatatgtatt acgcatcatt gccattcacc atgtttgaac cggagttatg
    23101 tcaaaaaacg gttctatggt ttgatcaata tggcgttaag tttcctggtt caaaatttac
    23161 aggaggtatc aatcattctc tgagtaattc gttatccagt gcgttactgg ctagtcttta
    23221 ttttgaacat actggggata caaaattctt tgagcggtgt ccgcaggttc tactgaatgc
    23281 ttcaagaatt attgaggaca tattagctca acgtcggtca ggggaaccaa tgctttttcc
    23341 atctgtttgg ttatcagacg cctttgcact tggaaagtat cataccggca gcaatctttg
    23401 tctttggaag gcctgtattg gacttgcaga aatttttgaa gccctagaac aactgagtct
    23461 tagcaagcga tacaaaaaca ttgcctgtaa actaaaggaa tcaatttgta aacaaatgac
    23521 tatcgatggt ccttttggtg agcaattttt ggagggaatc ggtgatgagg agaaaacaac
    23581 ctattcagtg aagcactatc aaaaaccgat tcttgagcaa gggttaatct ttttaagtga
    23641 tgtgattgtg gatggaaaaa ttaatttatt gatgcatgat ggagaagaat cagacactac
    23701 gttgatgcct ttttatcaat ttttagataa taaagatcat ttatatcaga acaccatggc
    23761 cttttctgct agttctttca atccaaccta tagcgaggaa atcaaaggca tcacttgggg
    23821 attagaatcc ggcgccactt ttcctggctt tatcactgtt ttaatgagcg agctgcacaa
    23881 ccctcaagct ttcgtaaccc gattagaaga actaatttgt ttggcagatt tagacggttc
    23941 gtggtggtgg tggccgtatc gcttagaggc tcaacaagga gaagtcgtgc gagactttgg
    24001 ctgcggcaaa tgcggctggg catcgggtct ttttgtcagc ctaatgatca gtcaatattt
    24061 cggattgaaa ttcaaaaaag gagtattgca aattgatcct gttgataatt taacgttttc
    24121 ttggaagaat ttgaagttcg gtcaagcctt catttcgatt gaatgtacgc aatccgagtt
    24181 gagtatttca aatttgtcag aaaagccatt gaaaataagt gatacgaaaa aaattcttca
    24241 cgtagaaaag ggaaaaacga ttcacattca aaggagaaaa agatgagtat actaaaaaat
    24301 attacccaat ttaaaaaaat ccagagtcga gcaatcactc ccgaaaatcc aacaggcgag
    24361 aaaggtaaag ctgcgatgtt gccaagcgag ctaggaccaa gccgcaaagg tcgtggcgca
    24421 attccgctga cttctggtga agaaactgtg attgcggata ttactggaac gggaataatt
    24481 cgtcatatgt ggatgacgat tcgtgatcga acagaatttg gcagttttgt tttacgtgat
    24541 ttaatcttaa gaatttattg ggatgggtcg gatagccctg ctgttgaaag tcctttaggg
    24601 gatttctttt gtaatgggtt tggagagcgt tgcgaggtga actcgttgcc gatagtggtt
    24661 aatcctacag ggggctttaa ttcctatttc gaaatgcctt tccaaacatc cgctaaaatt
    24721 acgatcgaga atttacatcc gaaggatatg tcctcatttt tttatacgat aaattacgct
    24781 ttggtggacg aattggaaga aaatagccta tattttcacg caaattggca tcgggaacgc
    24841 attaccaaat tacaggagga ttataagtta attgatcgat taaagggtca aggctattac
    24901 gtgggtactt accttgcgct tacctgccta gaacgttatt ggtggggcga aggcgagttt
    24961 aaattctaca ttgatgggga tagtgagtat ccgaccgtaa cctcaacagg ttcagaagat
    25021 tattttggcg gggcgtgggc ctttcatgag tacgatgagt tcggacgtcc acatgcgaaa
    25081 aactattcaa cagccttttt agggtatcct taccaatcaa atagagatgc cacaagagat
    25141 cgttttgaaa cgggaaaatt gaatgccgtt catgcctttg gtgacgacgc aatgccacga
    25201 catggtcttt atcgttggca tcttcaagac cccatctgtt ttaccgaaga tttatcggtc
    25261 actttacaac aaatcggcaa cgatgatgtt cgcttatttg agcggcaaga cgatgttgct
    25321 agtgtcgctt actggtattc aacagaagct tcaggaaata ctaaacgtca tttcactgat
    25381 cgagaacgct tgccgcgtta atgaagtgtt tttcacatat tcgaagggag gaacctatga
    25441 tgatatatgg ggcaattgaa gctggaggga ctaaatttgt ctgtgcagtc ggtactgagg
    25501 aattaacgat tttggaaaga gtcagttttc ccacaacaac tccagttgaa acaatgaagc
    25561 aggtcattga tttttttaaa ccttttaagg aacaattggc aggcatcggg gtcggctgct
    25621 ttggtccaat tgatattcaa tgcaaatcaa cgagtttcgg tcatatcaca tcaacaccaa
    25681 aacttgcttg gcaaaatttc aattttgtag gaacgctaaa gcaatatttc aatattccga
    25741 ttgaatggac aacagatgtc aatgcggctt gctatggtga atatgttgct ggttctggca
    25801 aagggttagc aggtgttgca tacttcactg tgggaacagg tatcggaggt ggtgccttgt
    25861 tcaatgggac tttcgtggaa gggttcagtc atccggaaat ggggcatatg ttgatcaagc
    25921 gacatccaaa ggacaatttt tcaggaaact gtcccttcca ccaagattgt ttagagggga
    25981 tggcagcagg accagcgatt gaaaaacggt tgggtgtaaa aggccagaat ttattggctg
    26041 acgattcgtt ttggcagatt gaagcctttt accttgccca atgtgcatac aatacaacac
    26101 tgatgttttc gccagataga attatttttg gcggtggtgt aatgaaacaa gaacacatga
    26161 agaaaaaagt tcaggataaa tttgttgagc ttataaatgg atatgttgaa ataccaccaa
    26221 ttgatagcta cattattacg cccgaattag gtgataatgc cggaataatc ggcggattag
    26281 cattggccag aaaagcggta agaaataagc aaccataatt aatgaatgtt tcattgatac
    26341 tcatgtcaaa agtatttaac cgagtaatca aatgatcaaa tgaagttgga taaagcgaaa
    26401 atgaattcaa ataaaaaggc tctaagtcaa atcgtgttgt tttcattaaa tcactgaaag
    26461 gaaatgcttc tgcgtttcct tttttctttt tgttgtgcgc tgtatacctt gaggatattc
    26521 actggtggcg tacacttaaa tagtaatata ttgtgttact ttatgtctgt ggtaatagtt
    26581 atagttgctt accaatgtat gttcattttt cgaaatgttg acttcataat ccttggctta
    26641 atgtttgaat ttttttggtg atagattttt tcagccgtat aaaataaatc gtaattctat
    26701 tatagagagt tgtgattata aaaagatagc aagaaaaaaa aagaaagttt ctatacattt
    26761 taaatatttt attcctattt ctattgctaa aaaagtagaa attctatatt tacctttaac
    26821 tctcgcttct cttgcaaatg tagttagcat tttaatcgat aataaactca ggtagttata
    26881 ttaccttgaa atgattgata attttgtcac ttctattttt tttgcaataa attttttatt
    26941 ttagtgaaaa ataagaaact atttctttga aggcgataag ttagaaaaat attattgtag
    27001 tcttttcttt attaggaatc atcactgttg tatcttatta ccttttctgt ttttcttatt
    27061 agagaaaaat aatttgagag gtagatagtt tttattggag gaagtaatta tgtatatttt
    27121 tgaaacaaaa atttttcatt gcaataattg caacaaagaa atttcatcgg gggaagaggt
    27181 ttggacaaaa atggaaattt ccgccaaaag taactgctcc tcaactgaaa tcaattaaag
    27241 aactagaatt tgagaatgca ctggtaattt gtatgacatg tactgatgaa gtatttcgaa
    27301 aacattttta aaggttgaga tgtatataga tttaaccaat catttatctc tctcggaaaa
    27361 ggaatattaa ctaaccagcg ggttatcaaa aataggtagg aaaactgtac ttaatggctt
    27421 atttcgcgct gattatgaga atatcagtct gtttgattaa tttttagggt tcaaaataca
    27481 gagacaaact ccaggtcggg tttcgccaca agcgaatta
//
LOCUS       DAXLPQ010000034        27100 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.034, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000034 DAXLPQ010000000
VERSION     DAXLPQ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.034"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(56..508)
                     /locus_tag="ACF3UO_001736"
     CDS             complement(56..508)
                     /locus_tag="ACF3UO_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657738.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(973..1341)
                     /locus_tag="ACF3UO_001737"
     CDS             complement(973..1341)
                     /locus_tag="ACF3UO_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFD3657739.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            1491..1973
                     /locus_tag="ACF3UO_001738"
     CDS             1491..1973
                     /locus_tag="ACF3UO_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFD3657740.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            2010..3020
                     /locus_tag="ACF3UO_001739"
     CDS             2010..3020
                     /locus_tag="ACF3UO_001739"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFD3657741.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(3135..3848)
                     /locus_tag="ACF3UO_001740"
     CDS             complement(3135..3848)
                     /locus_tag="ACF3UO_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657742.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(4021..4628)
                     /locus_tag="ACF3UO_001741"
                     /pseudo
     CDS             complement(4021..4628)
                     /locus_tag="ACF3UO_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            5112..5339
                     /locus_tag="ACF3UO_001742"
     CDS             5112..5339
                     /locus_tag="ACF3UO_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFD3657743.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            5355..6521
                     /gene="hemW"
                     /locus_tag="ACF3UO_001743"
     CDS             5355..6521
                     /gene="hemW"
                     /locus_tag="ACF3UO_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFD3657744.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6755..7798
                     /gene="hrcA"
                     /locus_tag="ACF3UO_001744"
     CDS             6755..7798
                     /gene="hrcA"
                     /locus_tag="ACF3UO_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFD3657745.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7892..8455
                     /gene="grpE"
                     /locus_tag="ACF3UO_001745"
     CDS             7892..8455
                     /gene="grpE"
                     /locus_tag="ACF3UO_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFD3657746.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            8506..10335
                     /gene="dnaK"
                     /locus_tag="ACF3UO_001746"
     CDS             8506..10335
                     /gene="dnaK"
                     /locus_tag="ACF3UO_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFD3657747.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            10486..11652
                     /gene="dnaJ"
                     /locus_tag="ACF3UO_001747"
     CDS             10486..11652
                     /gene="dnaJ"
                     /locus_tag="ACF3UO_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFD3657748.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(11734..12363)
                     /locus_tag="ACF3UO_001748"
     CDS             complement(11734..12363)
                     /locus_tag="ACF3UO_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657749.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            12375..12548
                     /locus_tag="ACF3UO_001749"
     CDS             12375..12548
                     /locus_tag="ACF3UO_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657750.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(12593..13330)
                     /locus_tag="ACF3UO_001750"
     CDS             complement(12593..13330)
                     /locus_tag="ACF3UO_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3657751.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(13332..14834)
                     /locus_tag="ACF3UO_001751"
     CDS             complement(13332..14834)
                     /locus_tag="ACF3UO_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFD3657752.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            15093..17087
                     /gene="uvrB"
                     /locus_tag="ACF3UO_001752"
     CDS             15093..17087
                     /gene="uvrB"
                     /locus_tag="ACF3UO_001752"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFD3657753.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            17097..19913
                     /gene="uvrA"
                     /locus_tag="ACF3UO_001753"
     CDS             17097..19913
                     /gene="uvrA"
                     /locus_tag="ACF3UO_001753"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFD3657754.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            20176..21441
                     /locus_tag="ACF3UO_001754"
     CDS             20176..21441
                     /locus_tag="ACF3UO_001754"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFD3657755.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            21445..22176
                     /locus_tag="ACF3UO_001755"
     CDS             21445..22176
                     /locus_tag="ACF3UO_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFD3657756.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            22311..23195
                     /gene="rapZ"
                     /locus_tag="ACF3UO_001756"
     CDS             22311..23195
                     /gene="rapZ"
                     /locus_tag="ACF3UO_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFD3657757.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            23192..24190
                     /gene="yvcK"
                     /locus_tag="ACF3UO_001757"
     CDS             23192..24190
                     /gene="yvcK"
                     /locus_tag="ACF3UO_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFD3657758.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            24224..25159
                     /gene="whiA"
                     /locus_tag="ACF3UO_001758"
     CDS             24224..25159
                     /gene="whiA"
                     /locus_tag="ACF3UO_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFD3657759.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            25702..26352
                     /locus_tag="ACF3UO_001759"
     CDS             25702..26352
                     /locus_tag="ACF3UO_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657760.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            26539..>27100
                     /locus_tag="ACF3UO_001760"
     CDS             26539..>27100
                     /locus_tag="ACF3UO_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HFD3657761.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         8932 a         4570 c         5721 g         7877 t
ORIGIN      
        1 aaaaatagcg ctagaatttc caacatctct ggaatttcta gcgcttttta attgtttaag
       61 atacaaggga aatatctgtc tggatcaata atttttcatt gatccattga ctaaagttta
      121 cgacataatt gaagttacca ccgattagta tctccgcatg attgtcttta taaagatcgt
      181 attgtaaaag acggtctttt ttatttgcgt aaacatcgtt atggtactgg actaattgtt
      241 ctcggaattg attgattgct gtaaaatcac gatattgaag gttgaaacgc atcgtgattg
      301 gtgcatttag catgaatcgc tgcatttctt ttgctgcttc ctctgcttga tctccgtata
      361 ggaactcaaa aagattacgt tcagaaaatt tccattgccc gccaaccttt gttcctttta
      421 gttttccttc atgaagataa tttctgatag aacgtgtagt aacacctaat tgttcggcta
      481 attcatttac tgagtaaaaa tctttcaatg ttcaccctcc tatgtgaatg gttctactga
      541 cttagttgat atttgcttaa tcacgaaatg tagaaagaac gattttaatt aaggtcattg
      601 taaaaatcaa gtcagaaaat tctaactttt atttctctaa agaaattcgt tctctcctaa
      661 agtgatatta tatttaaata tacctgaaaa taatgggcag tattatgaaa gatcactgat
      721 attttctcgt attttttcct tattcaaaag ttttgcagga aaattgctga aaaaataatt
      781 ttactaagta gaaaattcaa agccattcaa tcagtgattt ttttcagcac aagaaagact
      841 ccttataaaa atagcagata ctttgtcaat taagtgttta accagggatg ataaaaagga
      901 taggattgaa caaaacctgt ataaggtgat gaatagtttc ctcgccagta aaaggtttat
      961 tcgtataaag ctttatcgcc aaaatttatc atgacctttt ttatcttcaa tattaaatga
     1021 aatcaattgt tcaatcaatt cccagttgat tacacttttc caaggaactt tgatgacgtt
     1081 atccgtatat acgtagcctg cttcttggat atttttttca agggcacgaa tcgctgcttt
     1141 ttccggtgcg atagaaaaat gatttttagc aaaactaaat gcaataataa aggtaccatg
     1201 gtcagtaaac ataggttggt tccattttac agttgtgtct agctggggat acgtttctgt
     1261 tatcttagca aaaaggtctt tgatcttttg ttgatgttct ttttctttga tttgattgat
     1321 gatcggctga aatttttcca ttctaaaacg cctccattaa gtggtttgat ttattttacc
     1381 agaaaaacaa tagttatgta taaaaaacga acaaaacaca agtaatgttg taaccgctat
     1441 atttatatga taagatgtct caaataataa aatagaaaag agacataaaa atgattgact
     1501 tggcaaagaa attcttacac gaaaatatat attttgagtt gtatcatcat cgagccattt
     1561 atacaaatga agatgctttg gtaataaaga aagaacaagg atttacaggt acagagacca
     1621 aaagcttatt cttaaaagat aaaaaagata ataactacgt atatctgact tttactacga
     1681 aacaaacgga tttcaaagca ttagggaaga tcgtcggtaa aaggctttct attgtttcat
     1741 cagaacgcat ggaagaacaa acgggacaaa agcagggcgc tgtttctccg tttggttatg
     1801 aaaaacagat tccgattatt attgatgaag agctcttatc aaatgaaaaa cttgtttttg
     1861 caccaggtag accagatcaa acgatggtca tccaaacggt tgacttaaac aaaatcatcc
     1921 agctacttga gatgccgata tttttgatgc cggcaaacga aaaaaacaat taaccaagta
     1981 aaatagtgca tacttggagg tgaagcaaca tgataagtta tccattatta gaaagaaatg
     2041 caacgattgg ggttactgca ccatcctcag gcgtatcaga ggaacaccat tcgttactcg
     2101 aatcagcttt aaagagaatg gaagaaaaat ctttccaagt agttactgga aagacgcttt
     2161 ggacgcaaga taaggaaaaa tcaggtccag caagaaaacg agcagatgaa ttcaatcaaa
     2221 tgatgcaaga tgaaaatatc caaatgatct ttccgacttg gggaggagaa ttattgattg
     2281 agattctcga ttttgtcgat tttgatgctc tacaaccaaa atggatagta ggttattcag
     2341 atattagtac gttgctactt gctgtcacat taaaaacagg gatagccact gcacatggaa
     2401 ctaaccttat tgatttaaga ggagagtact tggatgaaac gacagcaatg tgggaaagtg
     2461 tactgaaaac aagagaagga gaatcgattc tacagcaatc ttctgaaaag tatcaaaaag
     2521 tgtggcccca tgagcattca tcatcttctg ttttccatct cactgaacca acaaattggc
     2581 aatcagtcag cggagatgca gtaaggatga agggacgatt attaggtggt tgtattgata
     2641 cgatcaggca tttaatcggt actccttatg gagatgtcca atcttttaaa agaaagtata
     2701 atgatggaaa gccgatcttg tggtttctag aaaactgtga gctatcgtca gttgatttaa
     2761 gaagatcact tgttcagatg aaactggcag gctggtttga tggcagctcg gggatcatgt
     2821 tcggtagaag tgcggcagag gatttgttag attataaaat gaaggatgta tacgaagatc
     2881 tgtcaaagga attaaaacta ccgatcttgt atgatattga ttgtggtcat gtaccgccac
     2941 aactgacatt gattaatggt gcctatgcag aagtagcggt agaagataga aaagcgactg
     3001 ttttgcaaac gtttatttaa aaaatttttt cctgccttgg agtctatcaa agaccaataa
     3061 atctaaatag aaaagaaagt gaaagaagct gacaaaatgc tgtcagcttc tttttgtata
     3121 acatattaga aagtctaatt atctataact gtcacatcga ttaactgttt cacgtcattg
     3181 ggatttcctg taggaatagc tactacagat gcattatcaa tgatttcttg agttgtttct
     3241 ctaatgaacg ctggataaga tgtttgatct gcaggcattt gccaatgtga aggaactgga
     3301 taactagtga ttgtcccgtc atggttactt gaatacacta aaactccctg gtaactgtat
     3361 ttcccagtga gcataaccac atctttcgga tagactgcac tccctgcatc ataaggggcg
     3421 ataggtgttc ctgcaggata atgaataaca tgtaattcga aatcacccga tgtatctcta
     3481 aaagtattac ctctaatagc tagccaaaca cgtgcgtact caatttgtag atcagaatat
     3541 cctgctaacg gatctattga ctgagaagac tgtgaggagg ttgtgtctat tgttgaagaa
     3601 gaaatatttg tctcaactgt actactagat gtagaagaag tattgggctc tgagacttta
     3661 ctgcttgttg aagatgtatt cgtttcagta gaagctgatt tctgagtact tgatttttca
     3721 gctgaactgg tttgtctgat tgaacttttg tctgtggtcg cagatggatc actattttct
     3781 ttactaggag acgtacatcc tacaaggaat aaagagacca acaataaaat aaaacctaac
     3841 tttttcatat aaaatacctc attatttttt taataccagt atagcataat cctgaatttt
     3901 tgaatccgta aaaccttgtc tatgaatata aatagagtgt atcttctttg ataaatgtca
     3961 gaaaaagtgt gacaaataat catcagtaaa attacttgtc acactattga taaggagtat
     4021 ttaattgaag agaatgatta ggagaaagga tctccgtact ttttatagta atcatagaat
     4081 ccaagtttgt atagacgaat cgttttttct cttatttctt ctgtttcaaa atggactgct
     4141 tgaagaatca agtctgtgaa ttctatagga gctgttccat tcgcagtaat caaattacga
     4201 tctttcacag cttgttgttc tataaaatct tctttattct gataattttc cgattctaac
     4261 caaggaaatt gcgcatttcc ggtgtgtttg taaccttgca ataatccgct ctgagctaaa
     4321 taatcaactg ccccacaaat agcagctact ggtacgtctg tttttaacaa tttatcgatt
     4381 atttgatata aatgatgatt ttttatgtcc catgaattgc caccgatcat aataaaaagg
     4441 tcaacttttt caggtatttg ttcgattaag taatcgattt ttgtttttaa tcctccaatg
     4501 gaagtgacct ctgattggat agaagcagtt ttgttttgcc atttctcatt ttggtttagt
     4561 gtgctagtaa tataagcacc ttcccaatcg gcatattcct ctaatagaaa cgtaatcgca
     4621 gttttcattt tcaagctctc ctttactatc tataacaagg acaacagttt taacctacag
     4681 acattcatta aaattgggta gcgacagcga aaacaacaat tcttaagttt tagacagagt
     4741 atacagatag tcaacttaat taaatacgaa ctaaataaaa atgacaggta atcatttttg
     4801 tttaccagca ttataacatt ttgcatacat ggatgacaaa agaaccaatt cccacttgct
     4861 tgagtacaat attaaaagaa actggaaggc aaaaagtaat tatagaaacg aaaaataaat
     4921 catatcgggc actcagacat gaaaacaacc ctagagatat ataactaggt aaccagttta
     4981 atgaaagaaa aaatcatcca agaagtcgat tcttggattt tttagtggat ttgttcgcca
     5041 aatacgttta gtatgcgtat atgagaggtt gtaagcaaag cgttgtggtc tgagcactta
     5101 aggaggaatc tgtgaaaata gcttttcata tttttgcaga ttttgactta atgccgaagg
     5161 tcagctttgc gattaccgtt tatcgagagg ctgtaaaagc accgtgtagc tccgatgaca
     5221 ataagcaagc atttttagag ctaggtttcc ttgattctaa atatgcggct tatttcaatg
     5281 agttggtgct tgaacgcgat tttaagaagg tcgaaaacag gcacgacttt tcgacgtaag
     5341 gagaaagaat ttcaatgata gaaacaataa atcccgcaga aaacaaggtt tctgcgtaca
     5401 ttcatatccc attttgcgag catatctgct attactgtga ttttaataaa gtttttttag
     5461 aagggcagcc agtagatgag tatgtggaaa tgctgctgaa tgaaatgaaa ataatgctag
     5521 aaagtcatcc gacagcgaat ttagaaacac tttacgtagg gggcgggaca ccaacttctt
     5581 tatctgctaa acaacttgat cgactgttat caggtgctag agagatcctg ccttttcaaa
     5641 atggtaatga gtttactgta gaagcgaatc caggtgattt gacccgtgaa aaacttcaag
     5701 taatgaaaaa ctatggcgtc aatcgtttat ccatgggagt gcagacattt gataatcgct
     5761 tattgaaaaa aattggacgt aaacacaccg cagaagatgt gtatcaaact atgcaatttt
     5821 tagaagcaga aaattttacc aatgtaagca tcgatttgat ttatgcatta ccgggacaaa
     5881 cactagaagg atatctggat actttggaaa aagctttggc tttggatctg cctcactatt
     5941 ctttgtactc attgatcctc gaaaacaaaa caatgttcat gaactgggta cgacaaggaa
     6001 gactcgaact gcctgatcag gaaacggaaa ccagaatgtt tgaagagacg attgaagcaa
     6061 tggaaaagca tggacgtcac caatatgaaa taagtaactt tgggctctcc ggacatgaat
     6121 ctcaacataa cctcatgtac tggaacaatg accactattt tgggtttgga gctggtgcta
     6181 gcggttatct tggagatatt cgttaccgca acaaaggacc aatccaacac tatttacgcc
     6241 cattacgagc aaatgaacgc ccggtattgg aagaagaaaa attgacacga aaaaatcaaa
     6301 tagaagaaga aatgttctta ggactaagaa aaaaaacagg gattactaaa aaacatttct
     6361 atgatcgcta tcaaaaaaca attgaatcgg tgtacggtga tgtgctaagg gaattagagc
     6421 aagaagggtt acttgttaat gaagaagacc gtgtttattt gacaccaaga gggacctttt
     6481 tggggaacaa tgtgtttgag cgctttttgt ttgaaaaata gtttaaagaa tatttgtttt
     6541 ttatctgaat ttaaataaaa aaagttcaaa aatacaataa aggactattg aaacgttgat
     6601 ataactggat ttacatcaat tatttagaat tagcactctt gtgtttagag tgctaaaaaa
     6661 tggagtcttt ctcttgacag gagaagggct tcttgctata tttataagtg gattagcact
     6721 tagaatatat gagtgctaat gagaggtgag gaagatgtta acaaagcgac aaaacgacat
     6781 tttacgtctg atcatccaac actatacgag tagtggcgtg cccgttggtt ccaaaacatt
     6841 gatgtctgag ggagtcaagg ccagctcagc aacgattcgc aatgatatga aagcattaga
     6901 agatgaagga ttgctgttga agactcactc ttcttctggg cggattccat ctgctttagg
     6961 ctatcgttat tacgtggatc atttgttaaa acctgctcgc gtagcagaag atgatttgct
     7021 gctgattcgt cagtctctag gcagagaatt tcatgaaatc aatgagatta ttaagcaatc
     7081 tgctgagata ttatctgagc tgacaagcta tacgactttt tcattgggac ctgaaataaa
     7141 agaccgccga ctgactggct ttcgtatcgt acccttgaat aatcgacaga ttattgctat
     7201 cgtcgtaaca gatatgggga atgtagaaag ccaagtgttc actcttcccg aatatatggg
     7261 aagtcaggaa ctagaaaaaa tggtacagat tgtaaacgac cgtctagtcg gagatcctct
     7321 gatgacggtg taccataaac ttcgtacgga gattccgatg attcttcata aatatttcca
     7381 aacgacagaa gggatgtctc agttatttga caccgttctt ggtcatgttt ttgaagataa
     7441 ggtttatgtc agtggacaaa tgaatctctt ggattatgag ccccgtcaag atcttgatca
     7501 gttcaaatcg atgttttctt ttatgaaaga ctcagacgga cttacacaaa tgatcactcc
     7561 gatggatagc aatattcata tcaagattgg tgctgaatta ggcaatgatt tattgcagaa
     7621 tatgagtatg attcaagcaa gttacgagat agatggtcat ggaagaggta caatagcctt
     7681 gttagggcct actagtatgc cttattctcg gatgttcggt ctagtcgatg tttatcgaag
     7741 agaactagca gctaaacttg ctgattacta ccgttcgctt gacttgtcaa actcgtaatg
     7801 tgaataacga agctatttgc agctgatcgt tctctctttc ttagtaagag caatcaaaca
     7861 gctgactgaa taatgaaagg aagactgtat cgtgaaagaa aatcaagaag aactagataa
     7921 agaaatgaca gatgctcagc cagaaccgga aatcgatgtc gaagctgcag aagattcggg
     7981 tatttcagaa gctgaagcgg aagaattcga aacagcgaaa ttaaaagctg agttagaaga
     8041 aatggaagat aaatacttgc gggctcgtgc tgaaatcgca aatatggcaa atcgaggaaa
     8101 aaatgagcgt gagcaattac aaaaataccg ttcacaagat ttagccaaaa aattacttcc
     8161 atcaattgac aacctggaac gtgcattagc cacagaagtg tcagatgatc aaggggcagg
     8221 tttgaaaaaa ggcgtggaaa tggtcttgga aagtttgcgt aacgcactgg aagaagaagg
     8281 aattgaaaaa atccctgcta aaggagaagc ctttgatcct aatcttcatc aagcagtaca
     8341 aactgttcca gcgactgaag atacaccagc cgatacgatt gtagaagtac tacaagaagg
     8401 ctacaaatta catgatcgcg tgttaagacc aaccatggtc attgttgcac aataattgtg
     8461 cggatataaa acttacactt tcaattaaag aaggagacgt taattatgag taaaattatc
     8521 ggtattgact taggtacgac taactctgca gtagcagtat tggaaggaaa cgaagcaaaa
     8581 atcatcgcta acccagaagg aaaccgtaca acaccttctg ttgtatcatt caaaaatgga
     8641 gaaatccaag taggggaagt tgcaaaacgt caagctgtga caaacccaaa tacgatttca
     8701 tcaatcaaac gccatatcgg tgaagcaggt tacaaagtag atgtagaagg taaatcatat
     8761 acaccacaag aaatctcagc aatgatcctt caatatatca aaggattcgc agaagactat
     8821 ttaggtgaaa aagtcgaaaa agcagttatc actgtgccag cttactttaa tgatgcacaa
     8881 cgtcaagcaa caaaagatgc tggtaagatc gctggtctag aagtagaacg tatcgtcaat
     8941 gaaccaactg cagctgctct tgcctatggt ttagataaaa cagatcgcga cgaaaaaatc
     9001 ttagtattcg accttggtgg cggtactttt gacgtatcta tccttgaact aggagacggt
     9061 gtctttgatg tattgtcaac agctggcgac aaccatctag gtggggacga ctttgataac
     9121 aaaatcatcg actacatggt agcagaattc aaaaaagaaa acagcattga cttgtctcaa
     9181 gacaaaatgg ctttacaacg cttgaaagac gctgctgaaa aagcgaaaaa agatttatct
     9241 ggcgtatcaa gcacacaaat cagcttgcca tttatcacag caggagaatc tggaccattg
     9301 catttggaaa tgacattgac acgtgcaaaa tttgatgaat taacagctga cttagtagaa
     9361 cgtacaaaag taccagtacg tcaagcgcta aaagatgcag gtttatcaca atcagaaatc
     9421 gacgaagtta ttttagtcgg tggatctact cgtatccctg cagttgtaga agcagtacgt
     9481 aaagaaacag gaaaagaacc aaacaaatca gttaaccctg atgaagtagt tgctatgggt
     9541 gctgctatcc aaggtggcgt gatcactggt gatgtgaaag atgttgtttt acttgacgtt
     9601 acaccattgt cattaggtat cgaaacaatg ggtggagtgt tcactaaatt gattgaccgc
     9661 aatacaacga ttccaacaag taaatcacaa gtattctcaa ctgcggcaga taatcaacca
     9721 gcagtagaca tccatgtatt acaaggtgaa cgcccaatgg ctgctgacaa caaaactcta
     9781 ggaagattcc aattgacaga tattccagca gctcctcgtg gtattccaca aatcgaagta
     9841 acattcgata ttgataaaaa cgggattgta aatgtatctg cgaaagatct aggtacacaa
     9901 aaagaacaaa aaatcacgat caaatcttct tcaggtctaa cagacgaaga aatcgaacgt
     9961 atggtaaaag atgcagaagc aaatgcagaa gcagataaag ctcgtaaaga ggaagttgac
    10021 ctacgtaatg atgtagatgc attgctattc tctgtggaca aaacattgaa agaattagaa
    10081 ggcaaagtgg acgaagaaga agtgaaaaaa gcagaaacag ctcgcgatga attgaaagcc
    10141 gctgttgaag caaacaacat cgaagaaatg aaaactaaac gcgatgcatt gaacgaaatc
    10201 gttcaaaact tgactgttaa actatacgaa caagcggcac aacaacaagc tcaagaaaac
    10261 ccagaagcag ctcaaggcgg agcagatgat gtcgttgatg ctgattttga agaagtcgat
    10321 ggcgacgata aataatcagt tcactgaatt tcgagagaag gccaaagttg ctactttggc
    10381 tttttctttt gaaaaatagt ttgaagtatc ggtttttgtt tcaaacaaaa tatgatatga
    10441 taacaagcga cgtgaaaatg atgagaacca ataggaggaa agcctatggc aacaaaacgt
    10501 gattattatg aagtcttagg gctctcaaaa ggagcatcag aagatgaaat aaagaaagct
    10561 tatcgtaagc tttcgaaaaa ataccatcct gacatcaata aagaacctga tgcggaagaa
    10621 aaattcaaag aagtatcaga agcatatgag attttaagtg acccgcaaaa acgcgctgca
    10681 tatgaccaat acgggcatgc aggcacagat ccaaattacg gtgctggtgg agctggtggc
    10741 ggatttggtg gattcggcgg cttctctggt ggcggcttcg gtggttttga agatatcttc
    10801 gactctttct ttggaggagg cggtcggtca gtcgatccaa atgcgcctcg tcaaggtgct
    10861 gatttgcaat atacggtcga cttgtctttt gaagaagcga tttttggtgt agaaaaagaa
    10921 atcaagtata atcgggaaga aatctgtcat acttgtggtg ggaacggtgc aaaaccaggc
    10981 acacaaccaa ctacttgtca taaatgtcat ggtgcaggta cgattaatgt agaacgccaa
    11041 acaccacttg gacgagtgat gagccgtcaa acttgtgatg tttgtcatgg gacagggaaa
    11101 gaaatcaaag aaccttgtcc aacctgtcat ggctcaggac atgagaagaa agcacattca
    11161 gttaaagtga atgtaccagc tggtgtagaa gaaggacaac aaatgcgttt agctggtcaa
    11221 ggagaagctg gagaaaacgg cggaccattt ggtgatttgt atgtggtctt ccgtgtagaa
    11281 gaaagtgata tctttgatcg tgaaggttct gaaatttact atgaattgcc tttaagtttt
    11341 gtacaagcag ctttggggga tgaagtccaa gtaccaactg tccatggaga tgtgaaattg
    11401 aagatccctg ctggaacaca gacaggtacg aacttccgtt tacgtggaaa aggcgctccg
    11461 aagttacgtg gtggtgcaac aggcgaccaa catgtcaaag taaaactgat cacaccgaaa
    11521 aatctaaatg aacaacaaag agaagcatta cgtgcattcg ctgaagctgg cggcatcaaa
    11581 gttgaagaac agcaagaaga cggtttcttc gataagttta aagatgcttt tggcgggaaa
    11641 aagcggaagt agtttttcta gtaaaaacgc taagtcatta ataattaaaa accagacgaa
    11701 caatcatatg ttcgcctggt ttttttgtag ttgtcatgtt tgtaccaaca aaaaagccag
    11761 ctttagaata tgataatcgt catagtttct aggggtataa ccagtgagag aatggaactt
    11821 gttcaatcga tattgcaagg tgtttttatg aataaataat tcttctgagc aatttttgat
    11881 gcttccgtta tttttactga agcatgccaa agtcttcttg aacaaatgta cttcttcttc
    11941 tgtcaggctt ttcaaaatac gttttacata taatgttcgt tgatctgacg ggattgctgg
    12001 taaaacgatc ccgaggtcta aatcttcaaa aaagcggatc tcgttcacag attgatggaa
    12061 agctatccat tcgcaaactt gtttggcatg aaggaaagat tgcggtgtct cttgctctgt
    12121 ataacaaagc gacccaattc caaagtttag ctgtaactga tacattttat taaactttgt
    12181 ctggatttta tcaagcaatg atagcaatga ggctctggaa atccgattga ctaggataat
    12241 gatttgttgt ctatgtacag tgagcaaagc ctgtccgtaa taagagaaga ccctttcgag
    12301 caactccaat aaaggattga tccgttcttg acacaattgc tgattgtcag aaagttgtcc
    12361 cacaactaca taatatggag aagaaaaatc aagctcaatt aagtgagggt ggtatcgact
    12421 atgtacttga tatcatcaat gaaccgatgg tactttctta tgcgatggaa caggtagagc
    12481 gattgcttgt ttgtgcagga aaacaagcga tgcggctgat acgattaggt gagaaaataa
    12541 gaagataaaa atacacggtc ccttcatggc gaccgtgcat ttttggtttt tattaaatat
    12601 ttaatacttt attcaagaaa tcttttgtcc gttcattttg cggattttca aagatttgtt
    12661 gaggcgttcc atcttctaaa aagtttccgt cgtcaatgaa catgacgcga ttggccactt
    12721 ctttagcgaa ccccatttcg tgcgtaacga taaccatcgt cataccttgt tctgctaact
    12781 ttttcatgac gttcaagaca tcaccgacca tttcaggatc gagtgcagaa gtaggctcat
    12841 caaaaagcat gatgtcaggg ttcatcgcta gagcacgagc aatagccaca cgctgttttt
    12901 gtccaccaga aagcatttca ggatacatat cttttttatc ttctagacca actgtctgca
    12961 gtaatttgat tgcttttttc tctgcttctt ctctagattc tttcttcagg tccatcggtg
    13021 ctaaaatgat gttttccaaa atagaaagat gagggaatag gttaaagtgt tggaatacca
    13081 ttccgatatg ttgtctcacc aagttgatat ctgtgctttt atccatcaag tgggcgccgt
    13141 caataataat ttcaccgtca gaaggttctt ctaaacgatt caagcaacgc aagaatgtac
    13201 tttttcctga acctgaaggg ccaatgatac agacgacatc tccttcgttg atggatacat
    13261 tgatgtcgtt taatactgtg ttatcgccgt attttttgac taaatgctca actaagattt
    13321 tttctgccat cttacttcac cttcttttct aaaacttttg ctaattttgt caatgctgtg
    13381 atcaaaatca agtacatgat cgcaatgatc aagtaaacat acgtactttg tgttgtacgt
    13441 gcaacaatga tcttaccagt ttgcagcaat tcgactacac cgattgcgga aatgatcgtt
    13501 gtgtctttta atgagataac gaactgattg acgaatgatg ggatcatgat gcgtatcgct
    13561 tgcggcaaaa tgattttttg cattgtccga ttataagaaa gacctaaact tctggaagct
    13621 tccatttgtc cgacaggaac ggcgttgatc ccgcctcgaa caatctctgc gatataagca
    13681 cttgcgttaa gagtcaaggt gataacacca gcaaggaagt caggaatcgt aaatccaacg
    13741 ataccaggca acccaaagaa aataaagaac gcaagaacca tcattggaat tcctcggatg
    13801 atatcgacat aaatactagc aattgtgcga agagcgcgta ttggtgctac actgaataat
    13861 ccaaaaatca caccgattac tatagccaaa gcaaaggaga tcaaagttag gagaattgtt
    13921 ctccaaagtc ctttcaacaa tgcttgatag ttgttttgga taagtccaag aaatgttgat
    13981 tcatcagcag tggaagactc actggaagtt tctgaaccat ccgctacata ttctttaata
    14041 atcttatcgt attcgcctgt tctttttaat tctttcaatc cttcattgaa catattaaga
    14101 agctcaggat tttgtccttt tttaacggca aatgcatatt ttccgccaga ttcttttttg
    14161 atcggtgttt ccaattcttg tccttgtttg atcgcataac cgattaccgg ataatcatcc
    14221 atcattgcat cgattgcgcc aacttttaac ccgtcgtaca attgatcagc agcatcaaaa
    14281 tatttgatag aatagccata ttcagattca tggtcgctta aaaattcagc actttcggta
    14341 ccaacttttg ctccgactgt ttttcctttc aaatcttcat aagacttgat cgaagtatct
    14401 ccttttttga cagctaattg gatcccgcta tcaaagtaag aatcagaaaa atcatagctt
    14461 ttctttcgtt catctgttac agtcattccg gcaatcattc cgtctgcttg tcctgattcc
    14521 aaagcttgca aagcagcaga gaaaccacgg tagtccattc ggatgttaaa tccttgcagt
    14581 ttggcgatgt tttccatcaa ttttacatcg atgccttcgt actcgccctt tgcgttttga
    14641 aattcaaatg gagcaaaagc agagtcactg gcaattacgt atacgtcttt tttgggctct
    14701 attttttgca ttgtctcgct tgtgcttgac tctgccgttg tagtgttgtc agcttgtgca
    14761 acatgaccaa acgcaagtgt cacaagtcct gtcattaaga aaacaaatga gtgaaataaa
    14821 tgctttcttt tcataatcaa cctcctaaat ttccaatatt ttattattat aggcgaaaag
    14881 tgctgaatca gacaagactg taagctcgaa aaaatgaaaa aaatgcgagt ttctaacatt
    14941 ttatgttata aaacataaca tgtataataa gataaaaaag tggcgaaagt atgttcggtg
    15001 tggtataatt ttttagtaag gaatgccttt gctttccttt tctttttatt ggtcgtaaaa
    15061 tgaaaaggaa tgaatgaaaa ggaggacgaa gaatgattga gagagatacc tcccgacact
    15121 ttgagcttgt ctcgaaatac caaccggctg gtgatcagcc tgaagcgatt aaccaattag
    15181 tggatggcgt agtcggcggg aaaaaagcac aaatcttatt aggtgcgact ggaacaggga
    15241 aaacatatac gatttccaat cttattgaga aagtgaataa accaacactg attattgccc
    15301 ataacaaaac attggctggt cagctgtacg gggaattcaa ggaatttttc cctaacaatg
    15361 ctgttgaata ttttgtttct tattatgatt attatcagcc tgaagcttat gtgccttcaa
    15421 gcgatacgta tatcgaaaaa gattcaagtg taaatgatga gatcgacaaa ttacgacatt
    15481 cggctactag ttcattatta gaaagaaatg atgtgatcgt cattgcatcc gtttcatgta
    15541 tttttggatt aggctcgcct tttgagtacc aaaaacaagt agtttcgatt cgacagggag
    15601 cagaactaga tcgcaatcag ttgattcgtg acttagtcag tatccaattc gaaagaaatg
    15661 atatagattt tcagcgcggt cgttttcgag tgcgcggtga tgtcgtggag atttttccgg
    15721 cttcaagaga tgaacgtgcc ttacgtgtgg agttttttgg agatgaggtc gaacgtatcc
    15781 gagaagtcaa tgcactgaca ggtgaagttt taggagaaac ggaacacgta gcaatcttcc
    15841 cggcgactca ctttgtgacg aatgatgaac atatggagca tgccgtagcg aatatcaaag
    15901 cggaattaga acagcgttta actgtcttgc gaaatgaaaa caaacttctg gaagctcaac
    15961 gtttagaaca gcgaaccaat tacgatattg aaatgatgtt agaaatgggc tacacgtcgg
    16021 gaattgaaaa ttattctcgg catatggacg gacgtaaaga aggtgaaccg ccttatacgc
    16081 tattggattt ctttcctgaa gattttttga tcgtggcgga cgaatcgcac gtaaccatgc
    16141 ctcaaatcag aggaatgtat aatggtgacc gagcgagaaa acagatgcta gtagattacg
    16201 gtttccgttt gccatctgct ttagacaatc ggccacttcg gttagaagag tttgaaaaac
    16261 atgtcaatca gatcatttat gtctctgcga cgccaggacc atatgaacat gaacaaacag
    16321 ataccgttat ccaacaaatc atccgtccga cagggctgct tgacccagtg atcgaagttc
    16381 gtccaatcat gggacaaatc gatgatctag taggcgaaat aaatgaacga gtcgaaaaag
    16441 accagcgggt gtttgtaacg acattgacga aaaaaatggc agaagacctc acagattatt
    16501 tcaaagaatt agggatcaaa gtcaaatatt tgcatagtga tatcaaaacg ctggaacgaa
    16561 cagaaatcat tcgagatctt cgattaggtg aatttgatgt gttagttgga atcaatttgc
    16621 ttcgtgaagg attagacgta cctgaagttt cccttgttgc tatcttggat gcggataaag
    16681 aaggcttttt acgtagtgaa cgttccttag tccaaacgat tggacgagct gctcggaatg
    16741 aagaaggtaa agtaatcatg tacgcagaca aagtaacaga ttctatgcgt ctagcgatgg
    16801 atgaaacgtc aagacgtcgt acgattcagc agaagtacaa tgaagaacat gggatcgttc
    16861 caaaaacgat cattaaagaa atccgagatt tgatttctat tacgaaagaa tcggaagatg
    16921 atacaaaaga agcggtacaa gtctcgtacg aagaaatgac gaaggaagaa aaagacacgt
    16981 tattgatgaa attagaaaaa gaaatgaaag atgcggcaaa agctttggat tttgaaacag
    17041 ccgcgaatgt gcgagatatg attttagaat taaaagcttc aaagtaggag gacaacatgg
    17101 ctaacgataa aattacgatt catggtgcac gtgcccataa cttgaaaaat atagatgtaa
    17161 cgattccacg agataaattc gtggtcgtta caggtttgtc cggttctgga aaaagttccc
    17221 tagcatttga tacgctgtac gctgaagggc agcggagata cgtagagagc ctttctgctt
    17281 atgctcgtca gtttttagga caaatggata agccggacgt agatagcatc gacggattga
    17341 gtccggcgat ttctattgat cagaaaacaa caagtaaaaa tcctcggtcg acagtaggta
    17401 ctgtgacgga aatcaatgac tatttacgct tgttgtttgc acgtgtagga catccgattt
    17461 gtcccaacga tcatatcgag attaccagtc aatcagtaga tcaaatggca gatcaagtaa
    17521 tggctttgcc tgagcgcaca aagatccaag tgttggcacc gatcgtggta aagaaaaaag
    17581 gacaacataa aaaaatattc gaacgaatcc aaaaagaggg atacgtccgc gttcgagtcg
    17641 atggtgagat ctatgattta agtgaagtgc ctgagctgga gaaaaacaaa aaacatgata
    17701 tcgcgatcgt catcgaccgg atcattgtga aagaagggat tcgttctcgc ctatttgatt
    17761 ctttagaggc ggccctgcga ttagcagacg gctatgctct ggttgacgtg atcggtgaag
    17821 aagaaatgtt gtttagcgaa cactatgcct gtccttattg cggatttact gttggcgaac
    17881 tagaaccaag actgttctca ttcaatgcgc cttttggagc ttgtccagac tgtgatggtt
    17941 taggtgtcaa attagaagtc gatcaagatt tagtgattcc agatagaacg aagacactta
    18001 gtcaaggtgc tatcgttcca tggaatccaa tcagctctca gtattatcct caaatgttag
    18061 cgcaggcttg tgaaagtttc ggtatcgatt tagatacacc attcgaagaa ttaccggaag
    18121 agcatcagga gatcatcttg aatgggacag atgatctttt ccatttccat tatgaaaatg
    18181 attttggtgg cgttcgcgat gtagaaacga ctttcgaagg ggtattgaag aatatcgagc
    18241 gtcgttatca tgatacgaac agtgatttca cgcgtgagca aatgcgtctt tatatgacag
    18301 aattaacttg tcagacatgt aaaggttatc gattgaatcc ccaagctcta tctgttcaaa
    18361 tcaatggaac gaatatcggg caaacaaatg agttgtctat tcaaaaagca gtagatttct
    18421 tctcaaactt aacgttatct gaacaagaga aagtaattgc caaaccgatt ttaaaagaag
    18481 taaatgacag actttcattc ttggaaaatg tgggactaga ctatctaact ttgagtcgcg
    18541 cttccggaac attatctggg ggagaagcgc agcgaatcag attggctaca caaattggat
    18601 cgaatctttc tggagttttg tatattttag atgaaccatc gatcggattg catcaacgcg
    18661 acaacgatcg actgattggc tcattaaaga aaatgcgtga tcttggcaac accctcgttg
    18721 tagtcgaaca tgatgaagat acgatgtggg cagcagatta tttgattgac gtcggacctg
    18781 gggccggaga acaaggcgga caaatcgtgg ctgcaggcac tcctgaagaa gtagctaatg
    18841 atgaaaattc tttgacaggg aaatatcttt cagggaaaaa atcaatccct gtaccaaaag
    18901 aacgccgtaa aggtaatggg aaagcaatca agatcactgg tgcttcagaa aacaatctga
    18961 aaaatattag tgttgaattt ccattaggag aatttgtagc agtcacaggt gtgtctggtt
    19021 ctggaaagag tacattggtc aatagtatct taaagaaatc gttagcgcaa aaattaaata
    19081 agaattctgc taagccaggt aaattcaaga caatttccgg ctacgaaagt atcgaaaaga
    19141 tcatcgatat cgatcaaagc ccaatcggcc ggacgccgag aagtaatcca gcgacttata
    19201 caagtgtatt tgatgatatc cgtgggttat ttgctcaaac gaacgaggca aaaatgcggg
    19261 gttataagaa agggcgtttt agtttcaacg taaaaggcgg tcgttgtgaa gcttgtcgcg
    19321 gggatggaat tattaagatc gaaatgcact ttttgcctga tgtctatgtt ccttgtgaag
    19381 tatgtcatgg taaacgatat aattctgaaa cattagaagt gcattacaaa ggaaaaagca
    19441 ttgctgatat tttggaaatg acagtagagg atgctgtaga attcttcaag cacattccaa
    19501 agattcatcg caaactgcaa acgattgttg atgttggctt aggttatgtg acgatggggc
    19561 aaccagcaac gacattgtcc ggtggtgagg cacaacggat gaaacttgcc agtgaattgc
    19621 acaaaatctc taatggaaag aatttctata tactagatga accaacgaca ggacttcata
    19681 gcgatgacat cgcccgcttg ttgcatgtat tacaaagatt agtagatgct ggtaacacag
    19741 ttttagtgat tgaacacaat ctagatgtaa tcaaaacagc agattatatc attgatttag
    19801 gaccagaagg tggagaaggt ggaggaacga tccttgcgac tggaacacca gaagaaatca
    19861 ttaacgtaaa agaaagttat acaggtcact atttgaaaaa aataatggta taaagaggat
    19921 agatagctga gatagttaaa aaaacataaa aaaatgaatt tttgcttgtt ttattaatat
    19981 cagtgttcta gaatcattac atggtagttc tttctacact gattggtata gataaaaact
    20041 tcctataagt tcaatccgtt caaaaaagaa ttgagcaatc ggaggacttt cctttgattg
    20101 cttttttctt tatggtatga tattccttgt gtagttggaa aagaaaaaca agagattatg
    20161 agtaagtgag agataatgat gaacagtatt gaaaatgaag aatttatccc tatattatta
    20221 ggaagcgaca tgaacgttta tggtatggca cgttctttta atgaagcata cggcaaaatc
    20281 tgccaagcat atgcttcgga tcagttagcc cctacccgct acagtaaaat tgtcaatgta
    20341 gaagttattc caggatttga taaagaccct gtatttatcg agacgatgct tcgtttggca
    20401 aaagaaagat attctgataa gagtaaaaaa tatcttttga ttgcttgtgg tgatggatat
    20461 gcagaattga tctcccaaca taaacaagag ctgtcagaat attttatctg tccatatatt
    20521 gattattctt tatttgaaag gctgatcaat aaagtaagct tttatgaagt ttgtgaagaa
    20581 tatgatcttc cgtatcctaa aacattgatc gtcagagaag aaatgttagt aaatggacat
    20641 ttggaacagg aattgccttt tgaattccca gttgctttga aacctgcaaa cagtgtggag
    20701 tatctttctg tccaatttga aggaagaaaa aaagctttta ttttagagac tagagaagag
    20761 ttcgatttaa ttttaggccg gatatacgaa gccggttata aaagtgaaat gattgtacaa
    20821 gattttatcc cgggtgatga tagtaatatg cgtgtgctaa atgcgtatgt agatgaagat
    20881 catcaagttc ggatgatgtg ccttggtcat ccactattag aagatcctac accagcatcg
    20941 attggtaatt acgttgtgat catgccagat tataacgaaa aaatctatca aaccattaag
    21001 gcatttttgg aaaaaatcga atatacaggc tttgccaatt tcgatatgaa gtatgatcct
    21061 agagatggag aatataaatt atttgaaatc aatttgagac aaggtcgtag cagtttcttt
    21121 gtgacattga acggcttgaa tctggctcgt tttgtcacag aagatcgagt gttcaacaaa
    21181 ccctttgttg aaacgaccta tggaacgaat caatcagata aagcaagatt atggatgggt
    21241 gtgcccaaaa aaatcttttt agaatatgct cgggaaaatg aagacaaaaa actagctgag
    21301 caaatgatca aagaaaatcg ttacggtact actgtatttt atgaaaaaga ccgatcaatc
    21361 aagcgctggt tgttgatgaa atatatgttc cataactata ttccaagatt caaaaagtat
    21421 tttcatgtga aagaaggcta gttcatggag aattttttca gtattttagg cggaatgggc
    21481 acgatggcga cagaaagttt tgttcgcttg atcaaccacc gaacgaaagc tacaaaagat
    21541 caagaatatt tgaattatgt cttattcaat catgcaacag ttcctgatcg tacagcttat
    21601 attttagatc gatcagaaga aaatccaatg ccgtttctgc tggatgatat tgagaaacaa
    21661 aatttattgc gaccaaactt cattgtgttg acttgtaaca ccgcacacta cttttttgaa
    21721 gagttacaag cggcaacgga tattcctatc ttgcatatgc caagagaagc agcaaatgaa
    21781 cttgtccgtc agcatacgac agggagagta gcgattctag gaacagaagg aagtatgaaa
    21841 gctggaatct atgaacgcga agtcaaaaat cttggtttcg aaacagtgat tcctgatact
    21901 gcgcttcaag aaaaaatcaa ttacctgatc tatcatgaga tcaaggaatc ggattatttg
    21961 aatcaagagc tctattacga aatcttagag gaagcggtag agcgcctaaa ctgtgaaaaa
    22021 gtcatcctag gttgcacaga attatctttg atgcatgaat ttgctgaaga taatcattac
    22081 ccagtgatcg atgctcaatc tattttagcg gatcgaacga tcgaacgtgc attagctgaa
    22141 agaagcgagg cattggatac agcatcggaa aagtaaaaaa attggatttg gggcaaatat
    22201 cctaaaagat atttggtcca aatctttttg taaaagaaaa agaaaactgg taatgatacg
    22261 cccgggatga tataatttta ttatgcacaa tgtgagaggg gttcgtaaat atgacagata
    22321 atttgcaatt agtcatcata acaggtatga gtggtgcagg gaaaacagta gctatccaaa
    22381 gttttgaaga tatgggctat ttttgtatcg ataatatgcc gcctcgattg attccaaaat
    22441 tctgggaatt gatcaaagaa tcaggtaaag tcacaaaaat ggctttagga gtggatttgc
    22501 gttctcgttc cttctttgaa gaaatccaaa acatgctgat cgaaatcgaa aatacgaact
    22561 tcatcgacac ttctatctta tttttagatg cttcagacga agaactagtg gctcgctaca
    22621 aagaaacaag acgagcacat ccaatggcga tggacggttt gatcactgaa gggatacgta
    22681 aagaacgggc gatactagac gacttgaaag cccaagcttc cgtgatcatt gatacgacaa
    22741 cattgacacc acgacaatta cgtgaaaaaa tcaatgagtc attcaaatca aagggagacc
    22801 aaggatttcg gatcgaattt gtatcatttg gttttaaata cgggttgccg atcgattcgg
    22861 atattgtgat ggatgtgcgt tttttgccca accctcatta tatcccggaa ctaagaccat
    22921 tgaccggaaa agatcagcca gtctatgatt atgtgatgtc ctttgatgaa acgcaatcat
    22981 tctaccataa atttttggat cttctggaaa ctgtattgcc tggatacatt aaagaaggaa
    23041 aaagcagctt gacagttgca atcggctgta caggcggtca acaccgttct gtggcattga
    23101 ctgaacgttt ggcaaatgct ttagggaaaa actataaagt caatgtgaca catcgggaca
    23161 aggataaaag gaaagagacg gtgaaccggt cgtgaaaatg aaaacctacc ggataagaaa
    23221 accaaagatc gtagtggtcg gcggtggcac tggtctgcca gttatcctga aaagtttacg
    23281 aaatcaagga gcagatatca cagcagtagt gactgttgca gatgatggtg gaagcagcgg
    23341 tgcaatcaga gaatcgatcg ctatggctcc tcctggtgac ttgagaaatg tcttagtggc
    23401 gttatcggat atgccacaat tctatgaaga tattttccaa taccgtttca aaaaggaaga
    23461 tcagttttta gccaatcata cgatcggtaa tctgatcatt gccgcagttt ccgagatgcg
    23521 gggaagcact tatgaggcga ttcaattatt agcaaaaatg atgcatgtag atggacatgt
    23581 ttatccttct tcagaaactc ctttgacctt gcatgctgtt tttaaagacg gaacgactgc
    23641 agtaggagaa tctaaaatcg cgatcaaccg taaaaccatt gaccgtgtgt atgtctgcaa
    23701 cacaaatgat aaaagtgaag ccaaagcggc tcgaaaagtc gtttcagcaa ttatggacgc
    23761 cgacatggtc gttttgggac ccggaagttt attcaccagt atccttccaa atttagtgat
    23821 accagaaatc ggcgaagcaa tgctcaagac aactgctgaa accgtctata tctgtaatat
    23881 catgacccaa aaaggggaaa cggaacattt cacagatgcc gatcatatac gtgttttaca
    23941 caagcatttg aatcagcctt ttatcgatac agtattggtc aatacggaaa aagtgcctga
    24001 agattatatg gacccagaga tctatgatga gtatctagta caagtcgcac acgacttcaa
    24061 cggattgaga aatgaaggat gtcgagtgat ttccaccgac tttttagaat tgaaagatgg
    24121 tggtgtcttc cacgatggag acaaagtagt agaagaattg ttccgtttag ttttcggttc
    24181 aaaatattaa gcaatttatt gttggagaaa ggaggagaat aggatgtcat ttgctgcaga
    24241 tgtgaagaaa gaactaactg gtttggaagt tcatcgagaa catgcgaaag cggaattagc
    24301 tgctttgctg cgaatgaacg gctctttagg tattgtgaac cagcagttta ttttgaacgt
    24361 ccaaacagaa aatgctgcaa ttgccagacg tatctattct cttttgaaag atcattatca
    24421 ggtacgaagt gagctactcg ttcgtaaaaa aatgaaatta aaaaagaaca atgtctatat
    24481 cgtccggttg aagcaaggca caaaagatgt gttgatggat cttgatatca tggatggtat
    24541 gatgttcaat ggacacgttt cggacgagat tatgggaaat tcgcaaaaaa tgcgttctta
    24601 cttacgtggt gcttttatgg cctcaggttc agtcaataat ccggaaacga gtcgttatca
    24661 tttggaaata ttttctattt atgaacagca taaccaagac atttgcgata tgttaaatta
    24721 ttacggtcta catgctcgaa cgcttgaacg gcgcaatggc tatatttcgt atttaaaagg
    24781 agcagaaaaa attgctgatt tcttaacatt gattggtgca accaactcaa tgctccgatt
    24841 tgaagatgtt cgaatcgtac gggatatgag aaattcggtc aatcgtctag tcaattgtga
    24901 gacagcaaat ctgaacaaga cgattgatgc ggcttctaaa caaatcgaaa acatcgaatt
    24961 gatcgaagca aaggtcggtc tacatgccct tcctgaaaaa cttcaggaaa tcgcagaact
    25021 tcggcttcaa catccagagg tcagcttgaa agaattaggg gaaatgattc cctcaggtgc
    25081 aatatcaaaa tcgggaatta atcaccgaat tcgcaaaata aatgaatttg cggaaaaact
    25141 gcgtgaagaa gcagtttaat ccaaagaaaa aactgataca tgaagcagga gatgcgaatg
    25201 tatcagtttt ttttaaaagc tatacttgct tttcttccgt caaactataa ttccaacttt
    25261 actggagtaa cataatgttg aaaggcttct attgtttttt aatacaatcg tataaaaagc
    25321 ggggagacaa ctgaatgaag attttagttt tatacataaa cttttgctta atatagaagt
    25381 cctgatatag ataggatcaa gtatttatct ataactggag attaattaaa aactggaagg
    25441 aactgctcga tcaaccttga gaactgtttt tcttacttct ggtcaagatt ctcgtggttg
    25501 gtggataagg atggttgata agttcattgg attagctagt cgaaaacaac caggtgtaat
    25561 taatgtagaa gttttaacaa ggggatggag tgatttattc agtgataatc ataagttcat
    25621 aaatagtaat tgggatgtat ggttggtata cgttatacct gaacttgaac tatcaagatt
    25681 tggtttagaa tttgagaatc gatgtttata aagggagggc aaaaaatgtg cttttttaca
    25741 acttttacta tcattatgat tgcagtactt tttatttttc tagatatagc aaagcgaaat
    25801 acagcatttt tattatatcg ggttttactt cgagcaggtc tcataacatt tatatcgatc
    25861 gttggatttt ttctattcac agttattgta tttatttgga gaactacagc accaccattg
    25921 ccagagatta catatggaga atttccgttt agtcttgaat atgaaataga tgaggaaaga
    25981 attttgattg aagatacggt gattgcagaa tttataggaa gttttagagg gaatgtgaca
    26041 actcaaccta gacgaagttg gagtataaaa cttttaaata atagtggaga gttgaaagca
    26101 tttcattatg aattcttaat aatagaaagt gaagatgtaa caatcacttt aagtagtggc
    26161 tctgctggat attttatgaa tgatggtgga agcaagccac agctcacagt ccgtgatcgt
    26221 attgcaggtt ttatgcattt ttctcactat gacttagaag aagctcgtaa aatacttgca
    26281 gaatatggga tcacattaat caattgggaa tatgcgccac cgataagaaa ttttttcaat
    26341 gattattatt agtcttataa aaaacagaat gtaaaattta tgtgcgcgag tatttagttt
    26401 tccatttttt gtttgataga tatatagcat tgttgaagca tgggatagtg gtgccaattt
    26461 tatcaatgag gttggtcagg cagttaacat aattggtgat gctataaatc catttaattg
    26521 gaattggagg aattaggtgt ggaaacagtg agattatgga tattcatgaa aaattttcgt
    26581 tcggctttga gatatgttat tctggaatca aaatcaggtt attatctgat tgacacagat
    26641 cactatactt tttggggagg ctaccttttt ccgattttta attggataat cccccataag
    26701 gttatgaaaa ttaacttgcc tgcagaagaa ataaatagat taatactcaa caaagattta
    26761 caaaggaaaa gagagaaaga acattctaat gttgcttgga taggtccagc atttgcagta
    26821 gtgacttctt caattgtcgg tcctatgcta gagagtattt atagtgattt ttctattgga
    26881 atacgttatt tatttgttac tttaagtata gctgttcttt tgtgcataaa gggttatgtt
    26941 agcaagaaga ataaagatat tttaacacta atcggtgtaa acaatttatc tagtactaaa
    27001 attatactgt ttcctgaatc tataaaagaa ggatcaaggt tgttgataat ttttataatg
    27061 cttatactgt tttctgtttt atttggggtg atgtttatag
//
LOCUS       DAXLPQ010000035        25499 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.035, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000035 DAXLPQ010000000
VERSION     DAXLPQ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.035"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            131..3658
                     /locus_tag="ACF3UO_001761"
     CDS             131..3658
                     /locus_tag="ACF3UO_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFD3657762.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="ACF3UO_001762"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="ACF3UO_001762"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFD3657763.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="ACF3UO_001763"
     CDS             7446..7787
                     /locus_tag="ACF3UO_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFD3657764.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="ACF3UO_001764"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="ACF3UO_001764"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFD3657765.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /gene="pheT"
                     /locus_tag="ACF3UO_001765"
     CDS             9144..11564
                     /gene="pheT"
                     /locus_tag="ACF3UO_001765"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFD3657766.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACF3UO_001766"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACF3UO_001766"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFD3657767.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12998..13735
                     /locus_tag="ACF3UO_001767"
     CDS             12998..13735
                     /locus_tag="ACF3UO_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3657768.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13749..14564
                     /locus_tag="ACF3UO_001768"
     CDS             13749..14564
                     /locus_tag="ACF3UO_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3657769.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14577..15224
                     /locus_tag="ACF3UO_001769"
     CDS             14577..15224
                     /locus_tag="ACF3UO_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3657770.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15240..15896
                     /locus_tag="ACF3UO_001770"
     CDS             15240..15896
                     /locus_tag="ACF3UO_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3657771.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16058..16879
                     /gene="racE"
                     /locus_tag="ACF3UO_001771"
     CDS             16058..16879
                     /gene="racE"
                     /locus_tag="ACF3UO_001771"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFD3657772.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16882..18237
                     /gene="rph"
                     /locus_tag="ACF3UO_001772"
     CDS             16882..18237
                     /gene="rph"
                     /locus_tag="ACF3UO_001772"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFD3657773.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18238..18756
                     /locus_tag="ACF3UO_001773"
     CDS             18238..18756
                     /locus_tag="ACF3UO_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3657774.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18863..19363
                     /gene="cbpB"
                     /locus_tag="ACF3UO_001774"
     CDS             18863..19363
                     /gene="cbpB"
                     /locus_tag="ACF3UO_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFD3657775.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19643..20563)
                     /locus_tag="ACF3UO_001775"
     CDS             complement(19643..20563)
                     /locus_tag="ACF3UO_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFD3657776.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20689..21741
                     /locus_tag="ACF3UO_001776"
     CDS             20689..21741
                     /locus_tag="ACF3UO_001776"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFD3657777.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="ACF3UO_001777"
     CDS             complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="ACF3UO_001777"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFD3657778.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22826..23266
                     /gene="fabZ"
                     /locus_tag="ACF3UO_001778"
     CDS             22826..23266
                     /gene="fabZ"
                     /locus_tag="ACF3UO_001778"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFD3657779.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23381..24142)
                     /locus_tag="ACF3UO_001779"
     CDS             complement(23381..24142)
                     /locus_tag="ACF3UO_001779"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3657780.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24331..25425
                     /locus_tag="ACF3UO_001780"
     CDS             24331..25425
                     /locus_tag="ACF3UO_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFD3657781.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4424 c         5383 g         7245 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgtg cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt attttattat acatctttaa
    12961 aagaaatctt actaaataat aatgggagtg taattctatg gcaatgatta aatttgatca
    13021 cgtggataaa tattatggca agttccacgc attaaaaaat atcaatctcg aattcgagaa
    13081 aggagaagtt gtcgttgtca ttggtccttc tggttcagga aagagcacga tgcttcgctg
    13141 tatcaatgga ttagagacga tctcttcagg taagctgctg attaatgata ctgacttgca
    13201 tgataaaaag acaaaactga cagaagtccg aaaaaacatc ggcatggttt tccaacattt
    13261 caatttgtac ccaaataaaa ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt
    13321 gaagcaagac caggcaactg cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat
    13381 gttagataag aaagattctt atccttccat gttatccggg ggacaacagc aacgggtggc
    13441 aatcgccaga ggtttagcga tgaatcctga gatgctgctg tttgatgaac ctacttctgc
    13501 tttggatccg gaaatgattg gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg
    13561 tatgtcaatg attgtcgtga cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt
    13621 tatcttcatg gctgatggag aagtattgga agacagcaga aatgtgagag actttttcga
    13681 aaatccaaat gaagtccgag cacagcaatt tatcagtaaa gttatcaatc attgatagga
    13741 ggaaaaagat gcgcaggtta aaaaaaatac gcctgatttt ccttttaggc attgcttttc
    13801 ttgcactagc cggatgtaaa ggaaatgggt tggcaaatga agatatttta gagcgaagca
    13861 aatctaccaa tgaaatcatc tggggtgtca agtatgatac tcgattattt ggaatgatgg
    13921 atattgagag cagaactgta caaggatttg atgtagatat tgcaaaagca atcactaaaa
    13981 agatccttgg tgacaatgga aaaacagaat ttgttgaagt cacttctaaa actcggattc
    14041 cattattgaa aaacggaaat atcgatgcaa ttattgcaac gatgacgatc acagatgaac
    14101 gaaaaaaaca ggttgacttt tcagatgtct atttcgatgc tggccaagct ttgttggtaa
    14161 agaaaggaag ccaaatcaaa agtgtagatg atttgaatgc ttctacaacg gttctagcag
    14221 tcaaaggttc tacatcggct gcgaatatcc gacagcatgc accagatgca aaaattttag
    14281 aattagaaaa ctatgcagaa gcatttactg ctttacaatc tggtcaggga gacgcgatga
    14341 ctacggataa tgcgattttg ttagggattg cagatgaaaa tccagagtat gagttagttg
    14401 gtggaacgtt tactaatgag ccttacggga ttgcgatcaa caaagggcaa gaaaacttct
    14461 tgaaagctgt taaccaagcg ctagaggaaa tgcatgcaga tggcacatac gataaaatct
    14521 atcaaaaatg gtttccaaat gaaactgaag gaaaagtaga gtaaggggga gaggcaatga
    14581 gcgaattgat acaaacttat ggaccaatct ttgtcgacgg gttcaagatc acattgtttt
    14641 cgagtgtctt agcacttgtg tttagtttga ttatcggaac gttaatggca atcttccaat
    14701 tatcaaagaa taaagtagtg agcgccttag caaaggcata tgtagaattt tttagaaaca
    14761 ttccattatt aatcatcgtg atgttttttt atgttgtcgt accgatttat tggtttaatc
    14821 tagatggatt ccaagcaggt acgattggat taacgatcta tacatctgct tttattgctg
    14881 aaacagtacg ttcagggatt caaaccgtac caaaaggtca aacagaagca ggactatctt
    14941 ctggttttac ctattcagaa atcatgcgtt atattgtttt accgcaagca ttcaaaatcg
    15001 ttatcccgcc attaggcaac caatttatca acctcgtaaa aaactcatct attttagcaa
    15061 tcgtagctgg tttagatttg atgtatcaag gagacttgat cgctagtgaa acattcaata
    15121 ccttcgatac gtatatcatc gttgggttat tttacttagt tatcacgcta ccgttatctt
    15181 acttaatggt ttatcttgag aaaaaatggg cggttcgttc atagaaggag gggaaataca
    15241 tggattttag cggcgctttt tcatggatga atatccgttt tttattggaa ggattaaagg
    15301 ttactgttga agtttcattg ttttcgatca tttttagttt cttgatcggt ggtctgacag
    15361 gtgtgattcg ttttgcgaat atccctttct tttccaaaat ccttggtgta gtgattgata
    15421 ttatacggaa tcttccatta ttattgatca ttttcttcac ttactttgcc ttacctcaaa
    15481 tcggcattca gatgaacatc ttctggtccg ctgtcgcagc attaacgatt tttgagtcag
    15541 ctatgttgtc ggaaattttc cgagctggac tcaatgctgt tccaaaagga cagatggaag
    15601 caggattatc aacgggactg acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag
    15661 catttaaatc aatgatcccg gcaattgtga gccaattgat ttcactgatc aaagatactt
    15721 cattagcagt aatcatttct ttacctgaac tttctcatca ggcacgtatt atttatggac
    15781 agaacaccaa ttatgtgctt ccgatgttca tcatcatgac acttatgtac ttcgtggtat
    15841 gttacgcgct ttctctgctt tccggttact tggaaaagag acggtacagt tattaataga
    15901 tgattctttt agcggttgtg gcaaactaaa gtcacaaccg cttttcctct ttccattcga
    15961 aaaaaagaga tttcgattgt tttaagcaag taagagcact tgaaaattca cgctaaaaag
    16021 tacacaatag ggaggataga atttattgaa aaaaaggatg atacgattga cagataatcg
    16081 ccctatcgga tttattgatt caggtgtcgg cggcttgact gtagtaaaag aagccctgaa
    16141 acaattaccg aatgaaaata ttttatttgt aggagacaca gcacgctgcc catatggccc
    16201 tagacccgcg gaacaggtaa tccagtatac ttgggaaatg acggattatc tggtggagca
    16261 aggaatcaag atgctggtga tcgcctgcaa taccgcaact gcggtggctt tagaagaaat
    16321 caaagctgct ctttctattc cagtcatcgg tgtgatcctt cccggtacta gagcggcagt
    16381 aaaaaaaaca caaaataaac aagttggcat tatcggtacg attggtacgg taaaaagtca
    16441 agcttatgaa aaagcactga aagagaaagt accagaattg actgtgacaa gtcttgcttg
    16501 tcccaaattt gtttcagttg tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat
    16561 tgtggcagaa acattagctc ctttaaccac taaaaaaatc gatacattga ttttgggatg
    16621 cacccattat ccattattac gccccatcat tcaaaatgta atgggagaaa atgttcaact
    16681 gatcgattct ggagcagaaa cagtaggtga agtatctatg ctgttagatt atttcaattt
    16741 gagcaattca ccgcaaaatg gtcggacatt atgccagttt tatacaactg gctctgccaa
    16801 acttttcgag gaaatagctg aagactggct tggaatcgga cacttaaatg tagaacatat
    16861 cgaattggga ggaaaataag gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa
    16921 ctggagcttc aaacaaatgt tttcaaatat ccagaaggat cggtagtgat ccgttttggt
    16981 gatacaacag ttatttgttc tgcaacaata gaaaattctg ttcccccttt tttgagagaa
    17041 acaggaacag gatgggtgac agcagaatat agtatgctgc ctcgagcaac gagtacgaga
    17101 aatcgtagag aaagcagcaa agggaaactt tctggtagaa caatggaaat ccagcgtctt
    17161 attggtcgtt ccttgcgtgc agtagtagac ttggaaaaat taggagaacg tagtatcatc
    17221 gtagactgcg atgtgatcca agcggatggc ggtactagaa cagcaagtat cactggggca
    17281 tttgtggcat tgaaattagc cattgaaaaa cttttaagag aaaaagaatt gtcagaagat
    17341 ccaataaaag aacatcttgc tgcagttagc gtaggaatct taccagatgg gacttgcgtc
    17401 acagatttgg attaccaaga agattccgca gcacttgtag acatgaatct tgtaatgaca
    17461 gaatctggaa aattcgtgga gattcaagga actggagaag aagcaacgtt tgatggtgaa
    17521 cagttgaatg aaatgctctt ttttggaaaa aacgcgattg aagatttgat caaagagcaa
    17581 aaacatgctt tgctaacaga gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca
    17641 atcatcattg cgacaagaaa tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa
    17701 gcgggatatc atgtaaaaac attacttgac tatcctgaat tgccagatgt ggaagaaact
    17761 ggcagcacat ttgaagaaaa tgcccgatta aaagcagaaa cgattgcaca attgcttgat
    17821 cagccagtct tagcagatga ttcaggtttg aaagtggatg ctttaggcgg tatgccagga
    17881 atctattctg cacgttttgc aggggaacaa aaaagtgatg cggggaataa cgccaaatta
    17941 ttatatgaat tgacagatgt gccggatgaa aaaagaacag cacaattcca ttgtacgtta
    18001 gtattcgcgg cacccaaaaa agacagcctt gtagtagaag cggaatggcc cggtcgagta
    18061 gcccgtatac catctggcga aaatggcttt gggtatgatc ctttatttat cccagaaggt
    18121 aagaaacaaa cagcagcaga attatcgagc gaagaaaaaa acaagatcag tcatcgggct
    18181 caagcaatga aaaaattgag tgccgagtgg aaacaatggc tggaaggaga gagatagatg
    18241 cggtatttag tagtaagtga taatcatgga gacagagata tcctcgttga cttagtagat
    18301 cgttatcgtt ctgaagtgga tatctttttc cattgtggtg attcggaatt agaagcttct
    18361 gacccattat gggatacatt ccaagtggtt caaggtaatt gtgattatgg accaggattc
    18421 gaacagaaaa aagtgatcca aactggtcag gatacagtat tcatgactca cggtcattta
    18481 tcgaatgtcc gatttggttt gacacagtta gcaatcgaag ctcgagctgc aactgccgat
    18541 atggtgtttt ttggtcatac ccatcaaata ggctgtgaga tggatcagaa aatcctgttt
    18601 ttgaatcctg gtagcatttc tcagcctaga ggcccgatcc aaatcccatc atatgctctt
    18661 atcgaaagtt tagatgacca aatttctgtt caatactata accgtgccca tcaggcagtt
    18721 gaagagttgg ccttttcttt ttcgagagag cgctgaataa aaaaactcta atttttaata
    18781 aaaataagct ttattttatg aattttgcat ccggtttcgg taaaatagta gtgttgaatg
    18841 aaatagaaat ggaggccatc agatgattgg acctatagta agagaaatgc tgctggaaaa
    18901 tcaggaaacg tttttgattc ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt
    18961 gtcccatggt ttacttgtgt tatcgaaggt cggttattcc aaaattcctg tattaggaaa
    19021 agatgatcac tttgtaggac tagtaagttt atcagatgtg gtcaataaaa tgattgactt
    19081 gcaaacaatc agcatggacc cgttagaagg actaacggtt gctgatgtga cagaaacaga
    19141 tgttccgaca attgatgaaa attgggaact agaagaagta ctccatttgt tagtcgattc
    19201 gcctttttta ccggttgtca cagaagatcg gattttcaaa ggaatcatta caagaaaaga
    19261 gctgcttaaa gccgtaaact tcatggtgca tgaattagaa cgtcgtaata tattgtctcc
    19321 gaaaatcgaa gaattaaaag aacaaatcga tatcgtgagc taaagaacga gaaactaaaa
    19381 gataatcaaa aaataagtag aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga
    19441 ggctgggaca aaagcgttta actccaagaa ataagaagga attcacgaaa attgcttttc
    19501 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ccgtttatac
    19561 gtgtttagag cgtgggacaa aagtgttctt tacttttgtc ccacgctctt tttagtgaga
    19621 ttcgttgcat cgtttgtcca aattattttc cgacagcaat tggactgttc ggaatcgtga
    19681 aaccagaagc tgtcaattct ttgacatagg agctcaagaa ctcttctttt aaggcatatt
    19741 gttttccgtt caatgcgtag cagaccgtac gaatcgcaaa attgctgttt ccaagatcca
    19801 ctaatccaaa gatagaaggt tcagtttgga gctcttcttg gtatttttca gctaatgtac
    19861 gatttactcg atcaatgatc tcatagattt tgtcatatcc ttcttcagga acaatccgaa
    19921 tatctaaaag tacttgcata tttgcacgag agagattgct gatcgtggtg atgtttcgat
    19981 tcgggatgaa atggacagta ccatccgttg ctttcagctg aagggtacgg ataccaacag
    20041 atacgacggt tccttcaatc gttaagtttg ctagcttgat gtagtcccca acatccatct
    20101 gttgttccat gataataaaa aatccggtaa taacatcact catgaaccct tgggcaccaa
    20161 gaccgattgc cacacctgca attccggcac cagccaaaag tgatccgatc ggcacaccga
    20221 tagcagataa aattgcatag ataaaaaaga aaccaagggt ataatgaaaa atagtattta
    20281 aaagactatg taaagtcttt aagcggctct cgtttagaat ggctttttta gaatactgat
    20341 taaaagactt atcaatcaga tattttccca cacggtgaag aatccaaaaa aggacgatca
    20401 aaaaaatcag atataaactt ttttggataa aggcagccaa aatggcgtcc caatcaatcc
    20461 cgtcccaaaa ccgctgaaac gcatttactt tgctgacagc ttgatctgtc aatgtctcgc
    20521 cagaagagtc tgtcgtaccg gcagttgcta ataatgaaaa cataaaatcc tcttttctaa
    20581 aatttgattc tttctgtatt gtaccaagaa gttttcaaaa aaggaaatag caaaaataac
    20641 tataatgaag gaaaaaagct gaaaataaaa tgacaaataa tatggataat gataaaatgt
    20701 ggagaaaata acgaaggtgg taagtatatg caaatcgatt ggaacaatct aggtttttct
    20761 tatatcaaaa ctccttggcg ttttattgcc aaatggaaag acggacaatg ggaagaagga
    20821 gaattgacag aagataatta cctgacgatt catgaaggct ctccagcgct tcattatggt
    20881 cagcaatgtt ttgaaggtct aaaagcttat cgtcgaaaag acggcaaggt caatctcttt
    20941 cgacctgaac aaaatagtcg acggatgaat caaagtgcta gacgattgct gatgccaatg
    21001 gtccctgaaa agatgttcgt tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt
    21061 gtgccgccct atggaacagg cgctacatta tacttgcgcc ctttactgat tggggtcggt
    21121 gaaaacattg gtgtccatcc agctccagaa tatttatttg tcgtcttctg tacgccagta
    21181 ggagcgtatt tcaaaggtgg actaaaacca acgaatttta ttgtatctga ttacgatcgt
    21241 gctgctccta aggggactgg tgcagcaaaa gtcggcggaa attacgcagc gagtttactt
    21301 ccaggaacag aagcaaaaga actggattac tcagattgtg tttatcttga tccagccaca
    21361 catacgaaaa tcgaagaagt aggtgcagca aatttctttg gaattacaaa agacggaaaa
    21421 ttcatcactc cgcaatcgcc ctctatctta ccaagtatca cgaaatattc cttgttgcag
    21481 ttagctgaag aacgactagg actgcaagca attgaaggag atattttcat tgatgatcta
    21541 gatcaatttg cagaagctgg tgcatgtggt acagcggctg ttatttctcc aatcggtggg
    21601 atttatcaca ataacaatct tcatgtattt tatagtgaaa cggaagtagg accagtaaca
    21661 aaacggttgt atgatgaatt gacaggtatt caatttggag acatagaagc accagaaggc
    21721 tggattgaag tcgtggaata atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa
    21781 atcaggaaga gactttaaaa agttttttcc tgatttttat atgttttact ttaaagaatg
    21841 caacaaaagt ttatgaaaga tggacacctt tgtcaacgta gataatatca ccgatgattc
    21901 cgctggaaag tgggctgatt aagaaagcac aagcattacc gacttcttcg atcgtcacac
    21961 cttgctgatc aggcgtacga gattcagata actggatcag tttttgatag tctttaacac
    22021 ctgtgacagc taatgttttg attgccccag ctgagattcc attgacccga attcctttag
    22081 gcgagaactc agctgccaaa taacggatag cagcttcaag agaagctttc gcaataccca
    22141 tcatgttata attcgggatt gcgcgttctg aacctagata agtcatgcta acgatcccgc
    22201 tgtttggtgc aagaaacggt tgtgcgtatt ttgatacagc aattaaagag tagctgctga
    22261 tatcttgagc taattgatag ccgtctctgg aaatatcaga cacatttccg gacaattctt
    22321 ctttgttggc gtaagcaact gcatggacaa ggccgtggat ctccccagca tattcaccga
    22381 tggcattcat tgctttttcg atgctttcgt cgctagaaac atcacattct acagtgaatg
    22441 cttcttcgcc gaccaatttg actaatgatt ttttcattcg ttcattttgg taagtataga
    22501 taatttctgc cccttgtttc aacattgctt cagcacaacc ccaagcaatg ctttttttgt
    22561 tagcgacgcc cataatgacg attttttttc cttctagaaa tgacataatg actctccttt
    22621 gtttctgata aaaatttgat agtcgtaaaa aaatagagaa taatagctaa aataacttct
    22681 tgatttctta attattagtc aaaatgtttt gattgtcaaa ctattttttc ttaaattaaa
    22741 aaaagattgc taaatattta ggaatatgat actttgatag tcaaagtaat gaaaatggca
    22801 attgcctgaa agaaggagtt taattatgtc ttacgtatta tctgctactg aagtaatgga
    22861 attgattcct aatcgttatc ctatttgtta tattgattat gtagatactt tagaaccagg
    22921 aaaaaagatc gttgcgacaa aaaatgtaac aatcaatgaa gattttttcc aaggtcactt
    22981 tcctgacaat ccagtgatgc cgggtgcgtt gattctagaa acactggcac aagcaggttc
    23041 gatacttatc ctaaaatcag aagagtttct aggaaaaaga gcttatatcg gtgggatcaa
    23101 taaggccaaa ttccgtcaaa aagttgttcc aggagatgtg ctgaaatgtc attttgaaat
    23161 caccaaaatg aagggatcag tcggtacagc gttatctgca gcatatgtag atgataaaaa
    23221 agtctgtgag tgcgagttca cgttcatcgt caaccaaaat gcttgactat aaaacctgat
    23281 atagcaaaac aaaaggaagc ttacttgctt tttatgtaaa aagaagacgc ctgaatccta
    23341 gcatacgttg tcatctatgc aggattcaga cgttattttt ttatttttgt tttgcttctt
    23401 gcagtatatt gattttatcg atttttactt cttcttttgg tttgtctgaa ctatctgttt
    23461 cgatatttgc aatagcatcc acgacatcca ttccttcaat cacttggccg aagacagtat
    23521 aatggccatc tagtgaagga taaccgccgt ttttataagc gtcgatgatt gcttgaggat
    23581 agtcgtcttt taaaagacca tcatgcatat catctgtatt ttgaacgata aagaactggc
    23641 tgccgttact gttaggatct tgtgagcgag ccatagataa cgcacctctt atattataaa
    23701 ggtggttgtt gatctctgtt tcaaatcctt ctccccaaat gctttcccct ccagtgccat
    23761 cgcctttagg atcgccacct tggatcatga aatctttgat gacgcgatgg aaagtcagtc
    23821 cgttgtagta accgtctttt gcatgtgtca taaagttttc aaccgctttt ggtgcgtgtt
    23881 cgggaaataa tttgattttg attgtgcctt tattcgtcac catttcgacc agatcttcat
    23941 tttcggcgac atctttcgtc aattgtggta attccaatgc gttcaaatcg acgctactgg
    24001 cagtcgtgct ttccgcagta gatgtacttt ttgaactttc tgtagacgaa ctagaagaag
    24061 tcgtgttgtt tgcagaacaa ccagcagcaa acagcaatgc tgctgctaaa ctaatactta
    24121 aaataacttt atttttcttc ataactgttc ctttccaatt tactattttg ttatctttaa
    24181 tgataacaaa atagagggaa aatacctact taaattattg gaatttatca tttattttaa
    24241 aagaaaaaga aaaggtgtag accatttact ttgtgtttgc tataatgtaa gtggatacaa
    24301 aaacgaaaag atgcaggagg aaatggtaat atgggaaaat taggaatctc gatttatcca
    24361 gaacggtcaa catttgaaaa ggacaaagcg tacttggatt tagctcataa gtatgggtat
    24421 aaacgggttt ttaccagttt gctgcagatc aatgatgata aagaaaaagt tctttcagaa
    24481 tttaaagaag tagttgatta cgcgaatagc ctaggcatgg aagtaatggt tgatatcaat
    24541 ccagcgttat ttgaacagtt ggagatttct tacgatgact tatctttttt ccataagatg
    24601 ggtgcctacg gggtccgctt agatatcgga ttcacaggag cagaagaagc aaaaatgacg
    24661 cgcaatcctt ttggtatcaa aatcgagatc aatatgagtt cgggcacgaa ttacgttgac
    24721 aacatcatga gttattcgcc aaacacggat aatttattag gttctcataa tttttatcct
    24781 catcgatact ctggtttagg atacgaacac tttgtttttt gttcagaaaa attcagaaaa
    24841 tataatttga atacgatggc attcgtcaat tcgcaatctg ctgagtttgg cccttggcct
    24901 acgcaagatg gcttgtgcac gctggaagac caccgagatc ttgaaattgc gacacaagtg
    24961 aagcatttaa tccttacagg attgattgat gatatttcta ttggaaatgc gtacgcaagt
    25021 gaagaagaat tgaaagaaat ggcagaagca tttaacgcgg attatccaac attgaaagta
    25081 gatacggaag aaggtattac agaaaacgaa cgaatctgct tgtttgataa ccttcatagt
    25141 tatcgagggg atcgctcaga atatatcctt cgttcaacga tgactcgtgt atactacaaa
    25201 gataaagatt tcccgcctca taatacgcga gatatgcatc atggggatgt actgattgac
    25261 aatgaagggt acggtcaata caaaggagaa acacaaatcg ccttgaagga tatgaaaaac
    25321 gacggacgtg tcaatgttgt aggaagaatc tccgatgacg aattattcct ccttgacttt
    25381 ttgaaaccat ggtcaagctt taaattaatt gaaaataaaa aatagataat tagttattgc
    25441 agaaataatc cgctagaaat agccagttat ttctgctttt ttattttgtt tttttatag
//
LOCUS       DAXLPQ010000036        24842 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.036, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000036 DAXLPQ010000000
VERSION     DAXLPQ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.036"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(301..864)
                     /locus_tag="ACF3UO_001781"
     CDS             complement(301..864)
                     /locus_tag="ACF3UO_001781"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFD3657782.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLIDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(879..1922)
                     /locus_tag="ACF3UO_001782"
     CDS             complement(879..1922)
                     /locus_tag="ACF3UO_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657783.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(2055..2459)
                     /locus_tag="ACF3UO_001783"
     CDS             complement(2055..2459)
                     /locus_tag="ACF3UO_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3657784.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(2659..2907)
                     /locus_tag="ACF3UO_001784"
     CDS             complement(2659..2907)
                     /locus_tag="ACF3UO_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005225422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3657785.1"
                     /translation="MHWLWVLIVGAIIGLIAGAITNKGGSMGWIANIVAGLVGSAIGQ
                     ALLGSWGPQLAGMALIPSIIGAIIVVAVVSFFLGRSRG"
     gene            complement(3542..4489)
                     /locus_tag="ACF3UO_001785"
     CDS             complement(3542..4489)
                     /locus_tag="ACF3UO_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005470715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3657786.1"
                     /translation="MYSYYKIEKNQIRESSEEDYNWLVVKHGNEEEKKELLTLFDLPE
                     DIFIGSDEPEEVSRLEHLRDTKLNNPFLYTLIDLSSNHQERIEKRLEPVTFILSKGLM
                     ITYVSRESNLVERLIEKHGSELRHFEDIIAFATLMIYTHYINGLKEIKKQIDQLDAAA
                     RKTTENNELFNLADTERDMVYLDHTLKDQNLTVNHLMERKEFLDKLDNESLVYDIKLR
                     QKFANKLVTIYRDLLETIGGLFSDMMDNNLNHLMKYLDSAALVVAVPSLIAGLWRINT
                     GGLPGKDNTIGTILVFGLAVLVGILTAVYLSKKDFSKTK"
     gene            4681..5508
                     /locus_tag="ACF3UO_001786"
     CDS             4681..5508
                     /locus_tag="ACF3UO_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFD3657787.1"
                     /translation="MFLHQKELQFEAKPDKPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMKKDPAIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDLLSVLLARDSYHQNLWAQAVKELEEKEGTILVPSTFPRNEERLDIAY
                     DFYNFSEGDQSKEGSWGKGKALDGEGEYQWLSTPKVEGKAPKLDPVTPKMYGTPPEK"
     gene            5650..6489
                     /locus_tag="ACF3UO_001787"
     CDS             5650..6489
                     /locus_tag="ACF3UO_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3657788.1"
                     /translation="MKAPLLTLNDGNMRPAVGIGTYQIRGGEGLSQLQAAIADGYRLI
                     DSSTNYDNEGIVGKAIRRSGVPRSEFYITSKLPGKYHGYDDALTSIQESLARMGLDYF
                     DAFLIHWPLPKRGKYIEAWQALVTAQKLGLIRSIGVSNFEPEHLDAIIEATGVTPAIN
                     QIEIHPYWVQEQMVAENRKRGIITEAWSPLGRGSAALKESIITDLANKYQKSAGQVIL
                     RWHVDRGILPLPKSRNLSHQRENLAIFDFELTEEEINAINRLNKEDGRIEGQDPNEYE
                     EFE"
     gene            complement(6741..7478)
                     /locus_tag="ACF3UO_001788"
     CDS             complement(6741..7478)
                     /locus_tag="ACF3UO_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008379144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase domain-containing protein"
                     /protein_id="HFD3657789.1"
                     /translation="MYQYVDKIHALLETVEKKEQHAIDEAIRLLTTANLEKHSIYIFG
                     ASHAGILAEEMYYRAGGMMTINAIFGRELMLDRSPITFTSKMERLEGYGTALAEIQPF
                     KEGDVLILHSVSGRNPVIIDLALAAKEKGVKIIALTNKTYSQSVTSRHSSGLRLFEVA
                     DLVIDNHGEIGDAGCQIKGMDQKVGPTSTVIGATILNTIIVEVCQQLKQAGIDYPPIF
                     YSANMDGGDELNQSLFEQYKEAIHYQL"
     gene            complement(7480..8730)
                     /locus_tag="ACF3UO_001789"
     CDS             complement(7480..8730)
                     /locus_tag="ACF3UO_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3657790.1"
                     /translation="MSFVTDHILKNPPVLLGLIAMIGLIVQRKPFAEVVKGSLTAAFG
                     MVALTAGVNMLTGTIAPINTAVQTQLGVQVADGLSDVTFTAEYGGTVGLAMFFGLILH
                     LLIARFTPVKTIFLTGHMLWWFPFVIVAGGVEGGMSGIPLLILGAVLSACYWSFMPWI
                     MRKYVWDATGDDSFLIGHPTGILSMVSGFVAKRVGNKEKSTEDLKVPENLSFFREISI
                     TGALVMFLMNIVVGIIAPVLVPEGGNLVMFAVQAGLNFGAGLLIMLYGVRLLINQIIP
                     AFQGIAEKVVPGAKPAFDVPILFNYRPNAVIIGFIVAMITSTILVIIVNTTNVFGILI
                     VPLVITSFFECGGAAVIGEGQGGLRGAVIGTIAASFVMVLLVGVSAVLFSTTIQNWIL
                     IFGGNDISLWGIIGRGLGSLFGGI"
     gene            complement(8733..9014)
                     /locus_tag="ACF3UO_001790"
     CDS             complement(8733..9014)
                     /locus_tag="ACF3UO_001790"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3657791.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIDKVIKELGLKATAENTDLSTAKA
                     TPADVYFTSHELLNDLQASVKAPVYPIKKYMDVAEVKMQMEKFLAEREG"
     gene            complement(9027..9458)
                     /locus_tag="ACF3UO_001791"
     CDS             complement(9027..9458)
                     /locus_tag="ACF3UO_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3657792.1"
                     /translation="MINLKKLLPEDHIETTNQILTWQEAVQLASQPLLNEKAIDQQYV
                     ANMIHSVEENGPYMVLADYFALMHARPGEGVFHQGMSLLVTKNEIDLAGKSVRIFLVL
                     AAKDNQSHLESLQEIMEVFMDQEKYQLILNGDKEQICQLFQ"
     gene            complement(9455..11092)
                     /locus_tag="ACF3UO_001792"
     CDS             complement(9455..11092)
                     /locus_tag="ACF3UO_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3657793.1"
                     /translation="MKNNYSLIEDRRMQIFKRLINGEHLSYQQLSDEYYVSRSSIAKD
                     IAYLKTLFVKENLLLRFDNSGTYFQGSESQIQRMLKRFILLTVEHGENLSVLTNVSLF
                     EKINAAFRHSITEKQMEIPESYIQSIVVSILLIVERSNQANQLDIEEKRQFGKLFLEF
                     DKYPLIYELLKEIEEQEIYHFSSKEVQYLTYLIVGSGLRFFMKNESIPFSFRGKVRNL
                     IQKVSEGIQIDLTQDSRLEEDLTIHLYQLFLRIEAQTTVVNPLLDEIKQHYPALYGVV
                     WFSLDDFLKAYHIGISEDEIGFVSIHFQAAVERMRQLNKIVFVCPNGVGTSSFISAKI
                     RRILPNVDSIETASVAKLKEMDISAIDFIISTIDLPDVSKPVVRISPMVTNRDMKRIM
                     NHYIDLIIDNEPIADKVKILQDTRMLIAPKIYFERFETKEQALDFLISQNDFSSENQR
                     TDFQRSVLEREALQSTYLDNGFAIPHGNPEFVSKTTFSVLILDRPVDWGNQKVDIIVL
                     LMIREDEAQEVEPVMKLIMQGIEDKEWFISKMLEVKS"
     gene            11306..12199
                     /locus_tag="ACF3UO_001793"
     CDS             11306..12199
                     /locus_tag="ACF3UO_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HFD3657794.1"
                     /translation="MKWRGGRQSSNVEDRSGRSAGSGGKIMVGGGIGTIVIAVLFFLF
                     SGGDLNSVTDILGGGQAANYQTENVASDEYTEEKEFSAVVFGHLEDYWNGVFEAEQTT
                     YQDPKLVLFTGSVQSACGNATSQVGPFYCPADQNVYLDLSFATELSQKYGASGDFAMA
                     YVIAHEVGHHVQNELGITQQLDKIRQQVSEKEYNQYSVRLELQADYLAGTFAKYLQGK
                     TYNGQPILEAGDIEEAITAANAIGDDTLQKEYQGYVVPDSFTHGTSKQRVEWFNRGFK
                     YGDLEHGDTFNEKNLDLVYGS"
     gene            12541..12622
                     /locus_tag="ACF3UO_001794"
     tRNA            12541..12622
                     /locus_tag="ACF3UO_001794"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12574..12576,aa:Leu,seq:cag)
     gene            12777..13280
                     /locus_tag="ACF3UO_001795"
     CDS             12777..13280
                     /locus_tag="ACF3UO_001795"
                     /inference="COORDINATES: protein motif:HMM:NF024954.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3657795.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLHNFPPRYYEYPGGVIACVTAYANLQHRS
                     KWLSSKK"
     gene            complement(13493..14248)
                     /locus_tag="ACF3UO_001796"
     CDS             complement(13493..14248)
                     /locus_tag="ACF3UO_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3657796.1"
                     /translation="MDFEQNVRLNFDLLSDNEKDMVFFIRTHKAQVVHMSIVELGEQL
                     LSSKSSVLRLAKKLGFRGYSEMKYSLEQSIVQSVIPPTDLIALLKDEINRTFQLADQT
                     NFQPILEQLKAAKTVVVYATGFTQNNFSKDFVNDLILSGRPAMLISGETNFEMLSHTL
                     TKDDFVIVTSLSGETPSIKSTIKNLNMNRIPLCGVTELGKNFLSEHSDFLLYYETREL
                     PSNLIEGSRSMIGLNILLSILSRKYREFILFDE"
     gene            complement(14355..16025)
                     /locus_tag="ACF3UO_001797"
     CDS             complement(14355..16025)
                     /locus_tag="ACF3UO_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3657797.1"
                     /translation="MNEWWKSSVVYQVYPQSFKDSNNDGIGDLMGIVEKLPYLAKLGV
                     DVIWLTPIFDSPLIDNGYDIRDYEKISENYGTLEDFKRLLEQAHQLNIRVILDLVVNH
                     TSNQHAWFIESQKNKENPYSDYYIWKDPKEDGSAPTNWGSTFGGSAWEYVESRKQYYL
                     HCFAKEQPDLNWENPKVRQSIYKMMKKWFDLGIDGFRMDVISLISKHPDYPDAPNSMP
                     YTKSYYVGASNGPRVHEFLQEMNREVLSKYDSLTVGETPNTNSRQAQLYTFPERKELN
                     MVFHFDHMHLDYGKYGKFSDVRFKLSDLRATLSEWQEALSDGWNSLYWSNHDQPRAVT
                     RFGDENEYRIESSKMLGTLLHMMKGTPFIFQGEEIGMKNVPFSSIDEYQDIETNYFYK
                     KMKEEGESDEYIKRAIYLKSRDNARTPMPWDHSKGYGFSNSDPWISFSPDNQQINVED
                     ALKNPNSVFYHYQKLISLRKNYPIIQHGTYKLINENDSAVFGYIREYKNELLVVICSF
                     SKESVPYELPKSLQGRKGVLLLSNYEQSPSELEDKFILRPYEALVYHI"
     gene            complement(16029..16448)
                     /locus_tag="ACF3UO_001798"
     CDS             complement(16029..16448)
                     /locus_tag="ACF3UO_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3657798.1"
                     /translation="MKKIIFASHHNLAVGLKDTVQYILPNVGEITAIAGYIDNSPIEE
                     KINEVMVRDNEDTDILIFTDMLGGSVNQAFIKYINQPNVYLITGMNLPVVLTILLNTL
                     NKRLTDNHIREAIQEAQDQLVYVNDYLKNIVVDEEDE"
     gene            complement(16461..17270)
                     /locus_tag="ACF3UO_001799"
     CDS             complement(16461..17270)
                     /locus_tag="ACF3UO_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3657799.1"
                     /translation="MNNEGNKLSKKDIRRAAFRYMFMACNIFNYENQQGPAVVYGLEK
                     ALRKIYPNDEDYRASLNNHFKYFNTTTWMANLLLGASLAMEEKDGVSSLDAVQSFKTG
                     MMGPLAGVGDTLVWVLYPTIMGSIAAYMGLEGNPTGAIIWLCLNLFFLFFRFKLFSIG
                     YTSGLKLVTALGSKLSIFTESASIMGLTVVGALIPSVVKMNVAVVFQSGKVKLPIQTE
                     ILDKIMPALLPAVLTIIVYKLIASKKMTVIQIIFSVIIFALILSFFGILKV"
     gene            complement(17263..18063)
                     /locus_tag="ACF3UO_001800"
     CDS             complement(17263..18063)
                     /locus_tag="ACF3UO_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3657800.1"
                     /translation="MEIIQGILIIILAVWVVLDQQGLVITTWFPIMIALFAGLIMGDM
                     TTAMVIGGTFQLMALGVANIGGSSVPNWGLAALVGIYVAIRTTNNIEEAKAVALAVGV
                     PVGMLGIQLDVLAKILNTYVTHAAQKAANKMDFKKMNQILWLGPVIFGLSTAIPTALC
                     VVFGDRIVRLILDFVPKWFTDGLSIAGSMLPVVGIALLLQVMPVKKYMTMLLIGFVLS
                     AYLNMPILGISIVGFALAYYFFTTEIKKAETASPVAANIVDEGDDFDE"
     gene            complement(18078..18554)
                     /locus_tag="ACF3UO_001801"
     CDS             complement(18078..18554)
                     /locus_tag="ACF3UO_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3657801.1"
                     /translation="MGLVLARIDQRLIHGIVVTQWAGATKAKRLMVVDDQVSKDDTQK
                     AAMRMSKPAGTGMSIIDTDTAIINFKLGKYDSHNVLMIVKEPSTLVKLAENGIDIPKV
                     NIGIMFDGEGKQTVKKMVSVDEQEIADLKKLEAMGIPVTFHFVPSDPEEPLDVRIK"
     gene            complement(18949..19428)
                     /gene="rlmH"
                     /locus_tag="ACF3UO_001802"
     CDS             complement(18949..19428)
                     /gene="rlmH"
                     /locus_tag="ACF3UO_001802"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFD3657802.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAHISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            19857..21143
                     /locus_tag="ACF3UO_001803"
     CDS             19857..21143
                     /locus_tag="ACF3UO_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFD3657803.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTTSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSGF
                     GGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKDG
                     TKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYANS
                     VTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKI
                     ASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQE
                     QILKIPSSVTNGVIVTNVQTATPAEKAGLKKYDVITKIDDKEVSSGVELQSALYKKKV
                     GDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(21318..21923)
                     /gene="ytpR"
                     /locus_tag="ACF3UO_001804"
     CDS             complement(21318..21923)
                     /gene="ytpR"
                     /locus_tag="ACF3UO_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFD3657804.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(22128..22592)
                     /locus_tag="ACF3UO_001805"
     CDS             complement(22128..22592)
                     /locus_tag="ACF3UO_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3657805.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(22614..22934)
                     /locus_tag="ACF3UO_001806"
     CDS             complement(22614..22934)
                     /locus_tag="ACF3UO_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFD3657806.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(23077..24156)
                     /gene="pepA"
                     /locus_tag="ACF3UO_001807"
     CDS             complement(23077..24156)
                     /gene="pepA"
                     /locus_tag="ACF3UO_001807"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFD3657807.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            24356..24706
                     /locus_tag="ACF3UO_001808"
     CDS             24356..24706
                     /locus_tag="ACF3UO_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFD3657808.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
BASE COUNT         7457 a         5210 c         4420 g         7755 t
ORIGIN      
        1 aatcatttgt ttaaaatttt cttcatatcg ggtcataaaa attcatcctc tcgtagataa
       61 gtttaattta ttcttgtctc tacgaaaagc tgtctaagat ttgatactaa caccaaactt
      121 cataaagtaa atcttttata catttccact tctagatggt cattcatgtt agaagaatca
      181 aactattttt ttactgtcgt aataatatta aaacactaga acaaatcaat taaattccat
      241 aaaatataaa taatagacct agcatcatct ggtataaaat ggatgctagg tccgttatat
      301 ttactcaaaa ttgattctac gaatagatct tcttatcatt tctattttag tagtcatgcg
      361 ttgttgttct tctaaaggtg gtaatggtat aagtagttta gataaatttg taccatttac
      421 atttggttgc ccagttccgt aagaaatttt ttctaataac ttccaatata atggcgagtc
      481 taagaagcag tctacatatt ctgataataa tttctcaact aacctaattc gaatcaagta
      541 agaagcaaaa acagattcct cacttatttc cttaaccaag aaactttttc ccatagttcc
      601 tcctgtcctt gctatcaaaa tgtcattttc ttctaatctt aaatcaatta gtttagaatt
      661 actaatatca cagtaaggca cactggacca atttacacgt ccctcttgta tatctgtgat
      721 tctcaaaaac ttaacattgc cttgtttttt cgccgaatct gtatagccat attgaatctt
      781 agtagaaata cttcctaaat aaacccatag tcgaacatcg ctagatgatt tttcttgtcg
      841 ttctttatga acaacagtga tcatcttgag ttgtccgact attttttagt tgcagcaatc
      901 tttttgggac gcttatttgc atgaagcaac gttgctaagt ctagtaataa aacattggct
      961 aacacaggat tggctttctc gcgatacgct gcggcgccac tttcaaacaa tactgctaga
     1021 cgatcttcta caacaacgat ttgttccaaa tacggtggaa atttgattcg ttttaggatc
     1081 cggctaggag agtcccgctc ggacactaag agttccgagg tataaggacc ataagaacga
     1141 ctggctaaga gataatggcc ataaaaagcc acaccttgaa tcttatcaga tgtttttctg
     1201 ctcattgtca cggttggttg gattttgtct ttgcggcgaa ttgctgtttt catttcagct
     1261 atcgtcggca atagatagaa agtcaactgt ccttcacctt ttagtgtgaa gttgccagat
     1321 accagttgat cattgttttg agtcaaatac gatgcttgtg gaatctctga gagatcagtt
     1381 gtcagccaat aagcgattgg ctgtcccgtc tcttcagatg tatctgctaa gatatcgatc
     1441 aaacgtaaag cggctactcg tccagtagca gatcctgtga ttgtcaacca taaaagttcc
     1501 cgttttgtat catatactaa gccccctaca tgtggccgtt taggtaaaat cagcagtttg
     1561 atcggctgtc ctgtttctct atccagtaca tgaataatag aatgatgctg atggtcatag
     1621 cagtaggcag aaataaacac aaaatcttga gaaaaagcca acccttgcgg cgtcatccat
     1681 tgacaaacct cattttcgcc ggtttccggc accaccattc ttgtttctgt taatccagga
     1741 atgttatatt gttttgcttc agccttttcc caagctgctt gaacaatagg ataccgtttt
     1801 aacttttttt caatatcctg atgtatccgt tgctgcttcc aatgcttaaa ctttaggaca
     1861 tagtaaacaa ggaggccaat gaccagcaac actaaaatca ttattgctac ccgctgtgtc
     1921 atttttttgc ctccttgttc tattcgatca atcgtacata taccgctatt aattaccgta
     1981 actacatgtt tcttttacta gcgtttcttt ataggatctt tcataatctc atttatagta
     2041 acattaagaa tcccttattc tactatagtc acttccacat caatattgcc tcttgttgct
     2101 ttagagtatg ggcaaaatgc gtgggcttct tctgcgattt tctctgcttg gtccttctca
     2161 agtcctggca aagaaacttc taaaacaacc ccgatttggt agcccccatc ttctaattga
     2221 aataaagata cccgtgcttt gacttcagaa tcagactcaa gattattttc ttccagcatg
     2281 tgttgaaccg cgccgttgaa gcaagatgcg tatccagccg caaaaagttg ttccggattt
     2341 gtcccttcac tatggattcc tgggcggtcg atcttcatgt gcatacttcc gtttggtgcc
     2401 tcaacctcgc catcacggcc tccacgattg atcattgctg tttcgtacat ttttttcatt
     2461 gagatcatcc tttctttcgt cgttctatat taagtgtaac gagtattttt taatctgaca
     2521 aaggtaatgc ttgcattcgg cgacatcagt tagacaacat cgatgatcag tgatagaagc
     2581 agtttatcta tacaaaaaaa gaagcagcga aaagctgctc cttaagataa taggtaaaat
     2641 tgctgatata tttgacgatt aacctcttga acgtcccaag aaaaatgata ctacagcaac
     2701 aacgatgatc gcaccaatga tagaaggaat caaagccatt cctgctaatt gaggacccca
     2761 gctacctaac aatgcttgtc caattgctga accaactaaa cctgcaacga tgttagcgat
     2821 ccatcccatt gatccacctt tatttgtaat tgctccggca atcaaaccga taatagctcc
     2881 tacgattaat acccataacc aatgcataat tttctctttc tttctgtgaa atatttatta
     2941 cacatattat gttacgcttc ttcttaaaaa tacacaaaaa ttttgctctt aaaaaaacaa
     3001 aaaaaattta aaacgttgtt atattaagga taagtcaact tttttggaat cgttaacact
     3061 cactgcaaga ggtcaaaaaa actgccgcag ctctttgaaa gcgtttcgat cagcaaaaag
     3121 ttattttctg ataaagggta cctagactat gtacgatttt ctttcattgt ctgctttcaa
     3181 ccgtcatctt ccctatgaat aaaagcaatc aaagaaacct gattgtcgta cacacctcat
     3241 tcactacatc cttctgatga aacatcaaaa caattggcat tcctttgatt ctgccttttg
     3301 tatttgaaac ctgcttcccc tcactatgta aaaggattat gagaaaaagc aacgatagaa
     3361 gtgagcgtat gcaatagcga gtaaagtaaa atataaattg ttcggattgt accccggcct
     3421 ttcttcttaa tatttttcat ttctcgcttc tcccctctgc ttattggaca gtcttcgcga
     3481 ttgtgaagtc acgaaaaaaa gcaactttgc ccagcgttca atgctagaca aagttgcttt
     3541 tttattttgt ttttgaaaag tctttctttg aaagatagac agcagtaagg atgcctacta
     3601 agacagctaa cccaaaaact agaatcgttc ctatcgtgtt atccttccca ggcagtccgc
     3661 cagtgttgat cctccaaagt ccagcaatca atgatggcac tgcaaccact aatgctgctg
     3721 aatctaaata tttcatcaaa tggttcaaat tattgtccat catatccgag aatagaccac
     3781 cgatggtttc caataaatcg cgatagatcg tgacaagctt gttggcaaat ttctgtcgca
     3841 gtttaatgtc gtaaactaac gattcattat ctaatttgtc taaaaactct tttcgttcca
     3901 tcaagtgatt cactgtaaga ttctgatctt tcaacgtgtg atccaaataa accatatctc
     3961 gttctgtgtc tgccagatta aatagttcat tattttcggt tgttttacgg gcagccgcat
     4021 ccaattggtc gatttgcttt ttaatctctt tcaacccatt gatatagtgg gtatagatca
     4081 ttaatgtggc aaaagcaatg atatcctcaa aatgtcgaag ctcacttcca tgtttctcga
     4141 tcaatcgctc aacgagattc gattctctag agacataggt gatcatcaat cctttggaaa
     4201 gaataaatgt gacaggttca aggcgttttt caatgcgttc ttgatgattt gaagaaagat
     4261 cgatcaatgt ataaagaaac ggattgttta atttagtgtc tcgtaaatgt tctaatcgag
     4321 aaacttcctc tggttcatcg gagccaataa aaatatcttc cggtaaatca aaaagtgtca
     4381 gcagctcttt tttttcttct tcatttccat gtttgactac caaccaatta tagtcttctt
     4441 cggatgattc tctgatttgg ttcttttcga ttttatagta cgaatacatt ttgcctctct
     4501 cctttaactc cttcacttct cttcaactat ctaatggcga ctgctttttg tcaagaaaaa
     4561 gcgctatttc aacggttttt attaatacgg aaataaagca agcgtttgat cagaccattc
     4621 taaataaacg tgagagaata tttttgggcc caataaaaat cattttagag gaggacaact
     4681 atgtttctac atcagaaaga actacagttc gaagcaaaac cagacaaacc aaatccatta
     4741 attgcgaagt atcttcaaga attgatcggt ggccagtatg gcgaaatgag tgtagcaatg
     4801 cagtatctct tccaaggttg gagctgccgt ggagaagaaa agtacaaaga tatgttgatg
     4861 gacattgcga cagaagaaat tggacacgtt gaaatgcttg ctacaatggt tgctcgttta
     4921 ttagaaggtg caccggtaga agatcaagaa gccgcaatga aaaaagaccc agcaattggc
     4981 gcaattatct ctggaatgaa tccacaacat gcgatcgttg ctggcttagg accacgtcca
     5041 gctgacagtg tcggtaatcc atggagtggc gcttatatca ttgccagcgg taatttactg
     5101 gcagacttcc gtgccaattt aaatgcagaa tcacaaggac gattacaagt cgctcgaatc
     5161 tatgaaatga ttgatgaccg tggagttaaa gacctcttat ccgtgctatt agctcgggac
     5221 agctatcacc aaaacctttg ggcacaagct gtcaaagaac ttgaagaaaa agagggtaca
     5281 atcttagtac cgagcacttt ccctcgtaat gaagaacggt tagacatcgc ctatgacttt
     5341 tacaatttct ctgaaggaga tcaaagtaaa gaaggctctt ggggaaaagg aaaagcactt
     5401 gatggtgaag gtgaatacca atggctttct acacctaaag ttgaaggcaa agcgccaaaa
     5461 ctagatcctg tcacaccaaa aatgtatggc acgccacctg aaaaataaat tgatcgaaac
     5521 gaataaaaag agcaatgatt ccattcacaa gaaatcattg ctcttttctt gtcttattga
     5581 gcaagttggt taccttaaag ctaaaaaagc gttagagtag aatgtataag aaaaaggagg
     5641 aatcattata tgaaagcacc tttacttaca ctaaatgacg gcaatatgcg cccagccgtg
     5701 ggcatcggta cctatcaaat tcgcggtggc gaaggcttaa gccagttgca agcagcgatt
     5761 gcagatggct atcgtttgat tgattcgtca acgaactatg acaatgaagg aatcgtcggt
     5821 aaagcgattc gccgatccgg tgtccctcgt tctgagtttt atatcacctc aaaattacca
     5881 ggaaaatatc atggatatga tgatgcactg accagtattc aagaatcgct ggcgcgcatg
     5941 ggattagatt actttgacgc ctttttgatc cactggccac tgcctaaacg cggcaagtac
     6001 attgaagcgt ggcaggcgtt agtgactgcg caaaaattag gtttgattcg ttctattggt
     6061 gtatctaact ttgaacctga acatttagat gccattattg aggcaactgg tgtcacacca
     6121 gccatcaatc aaatcgagat ccatccttac tgggtccaag aacaaatggt agcagaaaac
     6181 agaaaacgtg ggatcattac tgaagcatgg agtccattag gtcgcggcag cgcggcgctc
     6241 aaagaatcca tcatcactga tctagcaaat aaatatcaaa aatctgcggg tcaagtcatc
     6301 ttacgctggc acgtcgatcg cgggattcta ccactaccaa aatcccgaaa cctgagccat
     6361 cagcgagaaa acttagctat ttttgacttt gaattgactg aagaagaaat caatgcaatc
     6421 aatcgcttga acaaagaaga tggacgtatt gaaggtcaag atccgaatga atatgaagaa
     6481 tttgagtaaa gtgagacagc ataaagctcc tgagggattt cataggctca catcaattat
     6541 aggaattgga atggtcacaa aaaaagaact gcgagatgac ttgccccaat tgaattcctt
     6601 agatctacta gcagcaaggc tctactgaag tcttgctgct attttatgag aagtaaaaac
     6661 ttctgacacg atcagttttc atttggatta tgcttttctc acagttcttt ttctgagtta
     6721 aaacttctgt acaatcagcg ttacaactga taatgaatgg cttctttgta ttgttcaaac
     6781 aatgattggt tcaattcatc gccgccatcc atatttgcgg aataaaagat gggcggataa
     6841 tcgattcctg cttgtttcaa ttgttggcaa acttcgacga taatggtatt aaggatcgta
     6901 gcgccaatca ccgttgaagt aggccccact ttttgatcca tccccttaat ctgacaacct
     6961 gcatcaccaa tttctccatg attatcgatt acaagatcag cgacttcaaa cagacgaagg
     7021 cccgaagaat ggcggctagt gactgattgc gaatacgttt tgtttgttaa agcgataatt
     7081 ttgacgcctt tttcttttgc cgctagtgct aaatcgatta tgacaggatt acgacctgaa
     7141 actgagtgta aaatcagcac gtctccttct ttgaacggct ggatttccgc taatgcggtg
     7201 ccgtagcctt ctagtcgttc cattttgcta gtaaaagtga tgggactgcg atccaacatc
     7261 agttctcgtc caaagatcgc attgatcgtc atcatccctc ccgcgcgata gtacatttct
     7321 tctgccaaga tccccgcatg actagcccca aaaatataaa tcgaatgctt ttctagattt
     7381 gctgtagtca agagacgaat tgcctcatcg attgcatgct gttccttttt ttcaacggtt
     7441 tctagtaatg catgaatttt atcaacatat tgatacatat taaattcccc caaatagact
     7501 gccgagacca cgaccaatga ttccccaaag tgatatgtca ttgccaccaa agatcagaat
     7561 ccagttttga atcgttgtgc tgaatagaac ggcagataca ccaactaaca agaccatcac
     7621 aaatgatgcg gcaatggtac caatgactgc gccacgcaag ccgccttgtc cttctccaat
     7681 aactgctgcg ccgccacatt caaagaaact ggtgataact aatggtacga tcaagattcc
     7741 aaaaacattc gtcgtattga caatgatcac aaggatcgtt gaggtgatca tagctacgat
     7801 aaaaccaata atcacggcat tcggacgata attgaatagg atcggtacat caaaagctgg
     7861 tttggctcca gggacgactt tttcagcaat cccttggaaa gctggaataa tttggttgat
     7921 caataggcgg accccataaa gcatgatcaa gagtcctgcg ccaaagttca agcctgcttg
     7981 aacagcaaac atgaccagat tcccaccttc tgggacaaga actggtgcga taattcctac
     8041 aacaatattc atcaaaaaca tcaccaaggc acctgtaatg gaaatctcac ggaaaaagga
     8101 caggttttct ggcactttta aatcttctgt cgatttttct ttgtttccta ctcgttttgc
     8161 cacgaagccg gacaccatcg ataagatccc tgtaggatgt ccaatcaaga acgaatcatc
     8221 gccagtggca tcccaaacat atttccgcat gatccaaggc ataaatgacc aataacaagc
     8281 agataaaaca gctcctaaaa tcaataatgg aatccccgac attccacctt caaccccacc
     8341 agcaacgatc acaaatggga accaccataa catatgaccc gtcaagaaaa tcgtcttaac
     8401 tggtgtaaaa cgagcaatca ataagtgcaa gatcaatcca aaaaacatag ctaacccaac
     8461 agttcccccg tattctgctg tgaaggtcac atcagaaaga ccatcggcta cttgaacccc
     8521 caactgtgtc tgaaccgctg tgttgattgg tgcgatcgtt cccgtcagca tattgacccc
     8581 tgcggtcaat gctaccatcc caaaggctgc tgtcaacgag cctttcacca cttcggcaaa
     8641 aggttttcgt tgcacgatca acccgatcat tgcaatcagt ccgagcaata ctggcggatt
     8701 ctttaaaata tgatctgtga caaaactcat gattatccct ctctttcagc taaaaacttt
     8761 tccatttgca ttttgacttc agcgacatcc atatattttt tgatgggata gacaggtgct
     8821 ttgacggaag cttgcaaatc attcaataat tcgtggcttg taaaataaac atctgcagga
     8881 gttgcttttg cagtagacaa atccgtattc tcagcagtcg ccttcagccc cagctcctta
     8941 atcaccttat cgatcgtcat ctttaacacc attgaacttc caacaccaaa tccacacaca
     9001 gctaaaattt tcatcttctt ttcctcctat tggaataatt ggcaaatctg ttctttgtca
     9061 ccattcaaaa taagttgata cttttcctga tccataaaca cttccatgat ttcctgcaaa
     9121 ctttccaaat gactttgatt gtcttttgca gctaaaacaa ggaaaatacg gaccgacttg
     9181 ccagctaaat cgatttcgtt tttagtcact agcaaactca tcccttgatg aaagacacct
     9241 tcccccggac gagcatgcat caatgcaaag taatcagcca ataccatata cgggccattc
     9301 tcctcaacgc tatggatcat attagcgaca tattgttgat cgatggcttt ttcatttaat
     9361 agcggctgac tcgccaattg aactgcttct tgccaagtga ggatttgatt cgtggtctcg
     9421 atatgatcct caggcagtaa tttttttaaa ttgatcatga ttttacctcc aacatttttg
     9481 aaatgaacca ttctttgtct tcgatccctt gcatgatcaa cttcatgaca ggttctactt
     9541 cttgggcctc atcttctcgt atcattagta acacgatgat atcgactttt tggttgcccc
     9601 aatcaacagg acgatccaaa atcaatacag aaaaggtcgt ttttgaaaca aactcaggat
     9661 tgccatgagg tatggcaaaa ccgttatcta aataggtcga ctgcaatgct tctcgttcta
     9721 agacggaacg ctgaaagtcc gtacgctgat tttccgacga aaagtcattt tgactgatca
     9781 gaaaatccag tgcttgttct ttggtctcaa atcgttcaaa ataaatcttc ggtgcaatca
     9841 acatccgtgt atcttgcagg attttcacct tatccgcaat cggttcatta tcaataatca
     9901 aatcgatata gtgattcatg atccgcttca tgtctcgatt ggtcaccatc ggcgagatgc
     9961 ggacgactgg tttggaaaca tcaggtaaat cgatcgtgga aataatgaaa tcgatggcag
    10021 aaatatccat ctctttgagc ttagcgacag aagcggtttc aatactatcg acattaggca
    10081 atattcgacg aatcttggca gaaataaatg aactggtgcc aacaccgttc ggacaaacaa
    10141 agacgatttt attcaattgc cgcatccgtt ctactgcagc ttgaaagtga atcgaaacaa
    10201 acccgatttc atcctcagat attccaatat ggtaggcctt tagaaagtcg tccaaagaga
    10261 accaaacgac cccatacaac gccggataat gctgtttgat ctcatctagc aatggattga
    10321 ctacagtagt ttgggcctca atgcgtaaaa acagctggta caaatgaatc gtcaaatctt
    10381 cttctaagcg actatcctgt gtcaaatcga tctggatgcc ttcactgact ttctgaatca
    10441 gatttctgac tttccctcga aaagagaacg gaatcgattc gttcttcata aaaaaacgta
    10501 agccactacc tacaatgaga taggttaggt actgaacttc tttcgatgaa aaatggtaga
    10561 tttcttgttc ttcaatttct ttcaacaatt cataaatcaa cggatacttg tcaaattcca
    10621 aaaacaattt tccaaattgg cgcttctctt ctatatccag ctgatttgcc tgattcgagc
    10681 gctcgacaat cagcaagatc gaaacaacga tgctttggat gtagctttct gggatctcca
    10741 tttgcttttc ggtgatcgaa tggcgaaaag ccgcatttat cttttcaaat aatgacacat
    10801 ttgtcagaac agaaaggttc tccccatgct ccacagtaag gagaatgaat cgcttcaaca
    10861 ttcgttggat ttgtgactcg cttccttgaa aataagtgcc tgaattatca aaacgcaaca
    10921 gtaaattttc tttgacaaac agtgttttta gataagcgat atccttggcg atactgctcc
    10981 tagaaacata atactcatca gaaagttgct ggtaactcaa gtgctcccca ttgatcagcc
    11041 gcttaaaaat ttgcatgcgt cggtcttcga tcaaagaata attgtttttc atttgctcac
    11101 cctctacctt tattctagtg ataccttaac aaatatgaag accaattgtt agattaaaaa
    11161 atgattaaaa ggtgtgcaca ccctttccct tgatagcaat atcggtcgtt tgttccgcaa
    11221 aatcgcttca agcaagccaa acttttctca tcttcctcgt tttctcttat aataaatgta
    11281 aacagtcaaa tgaggaggaa acaaaatgaa atggcgtggg ggtagacaaa gttccaatgt
    11341 ggaagaccgc tctggtcgtt ccgcaggttc aggaggaaaa ataatggtcg gcggtggtat
    11401 cggtacgatt gttatcgcag tcctcttttt tctattcagt gggggtgatt taaactccgt
    11461 cacagatatt ttaggaggcg gacaagccgc taattatcaa acagaaaatg tggcttcaga
    11521 cgagtataca gaggaaaaag aattctccgc tgtcgtcttc ggccatttgg aagattattg
    11581 gaatggtgtt tttgaagcag aacagactac gtatcaagat cctaaactgg ttttatttac
    11641 aggaagtgtt caatcggctt gtgggaatgc aacttctcaa gttggtccct tttattgccc
    11701 tgccgatcaa aatgtttatc tggatctcag ctttgcaaca gaactttctc aaaagtatgg
    11761 ggccagcgga gattttgcca tggcctatgt cattgctcat gaagttggtc atcacgtaca
    11821 aaacgaactt ggtattacac agcaactcga taagatccgc caacaggttt ctgaaaaaga
    11881 atacaatcaa tatagtgttc gtttggaact acaagcggat tatttagccg gtacatttgc
    11941 caagtatcta caaggaaaaa cttataacgg ccaaccgatt ttagaagctg gtgatatcga
    12001 agaggctatc acagctgcta atgccattgg tgatgatacg ttacaaaagg aataccaagg
    12061 atatgtcgta ccagatagtt ttactcatgg gacttcaaaa caacgagttg aatggttcaa
    12121 ccgggggttc aaatatggtg atttggagca tggagacacc ttcaatgaaa aaaaccttga
    12181 tttggtctac ggatcataac aaaaacgttc ctttttagtc actctttttt cacatttggg
    12241 cggtatagtt tattcatacc aacaaaccct aactttttca ttttactcct tgcctgccag
    12301 tccccgctgg caggcccttt tttttcatgg tgctatttta gtttttttta acctttggcc
    12361 tgtttttttc tttaaaacgc taagggttga tcacaatttt ttcatatttt ccggttacta
    12421 tataaataac ccaacaaaca acccaacttt ttcattttta ctccttgtct gtcagtcccc
    12481 gctgacagac ttattttttt tcttgccaaa attctcaaaa tgcgctaagg ttatttatgc
    12541 gcggaagtgg cggaatggca gacgcgcacg cttcaggcgc gtgtgagtat atctcgtgtg
    12601 ggttcaactc ccatcttccg cattttgagc agatcatctt ggatgatctg ctctttttta
    12661 tgtgtttctt ttgtctaaat aaagaaaaaa gcttaagcta tataaattga gttaaattgt
    12721 attcgttttt cctcctatag gcgtatacta aagaaaacac ttgaggagtg gggaacatgg
    12781 aaacagaacg ccaaatccgt gaattggaaa aagcgatgaa tacgacagac aaccgccggt
    12841 tgtacgagcg tttcctggca gtcaagttgg ttcttgaagg ccacacccgg aaagaagccg
    12901 ggcacaccat cggccgcgac gagcatactg tcagccacta tgtgaaaaac tactgccata
    12961 atggaatcca aggtttagtc tccaaaaaac aaagcggacg accttcacgg ctgacagatg
    13021 aacaggaagc ggaactggtc caaatcgtcg cctaccacac tccggaggaa gtaggtttca
    13081 aatcccgtgc caattggaca ttggcgattg tgtgtgacct gattctccgg gaatggagtt
    13141 atggatatac gcaaaaaggc gtggcggacc tacataactt tccccctaga tattacgaat
    13201 atccaggggg tgttattgca tgcgtaacag cctatgctaa tttacaacat agatcgaagt
    13261 ggcttagctc taaaaaataa gccgcatctt tgtcagatac gactgtttag cattgctcat
    13321 tcaattagtt gatgattttt tcatcaaatt tcagatatag ttgaatattt cctttgttca
    13381 gcttatcaaa tgtcacttta tcaatgaatg ttcgatagat ttccttgttc tcactcttga
    13441 aacgattggc taacaacttt tcaacacttg ctcctttgtt tcgaaatgga ggctactcat
    13501 caaaaagaat aaattcacgg tactttctag agagtattga tagcaaaata tttaatccaa
    13561 tcattgaacg acttccttca attaaattgc ttggaagctc tcttgtctca taatataaca
    13621 aaaagtcgga atgctcgctg aggaaatttt ttcccagctc agtaactccg caaagtggaa
    13681 ttcggttcat attcaaattt ttgattgttg atttgatgct tggtgtctca ccgcttagag
    13741 acgtaacgat cacaaaatca tcttttgtca aagtatggct taacatttca aagtttgttt
    13801 cacctgaaat taacatggct ggtcgtcccg ataaaatcaa atcgtttaca aagtcttttg
    13861 aaaagttatt ttgcgtaaag cctgtcgcat agacaactac tgtttttgcc gcttttagct
    13921 gttctaatat cggttggaaa tttgtttggt ccgctaattg aaaagttcgg ttgatttcat
    13981 ctttcaatag tgcgataaga tctgtcggtg gaataaccga ttgaacgatg ctctgttcaa
    14041 gagaatattt catttcagaa tacccacgaa atcccaattt ttttgctaaa cgtaagacag
    14101 aacttttaga agacaataat tgttctccca attctacaat ggacatgtga actacttgag
    14161 ctttatgcgt acgaataaaa aaaaccatat ctttttcatt atctgagagc aaatcaaagt
    14221 ttagtcgaac attttgttca aaatccattt tctcacctct catatataca gaaggaattt
    14281 cggataaaac ttgcgctgtt ttatccgaaa ttctttctta ttgcccaaat tctaacacag
    14341 tttttacgtg cttgctatat atgataaaca agtgcttcgt aaggtcgtaa tataaactta
    14401 tcttccaatt cagatggtga ttgctcataa tttgatagaa gaagaacccc ttttcgacct
    14461 tgcaatgatt taggtaattc atagggaaca gactcttttg aaaaagaaca gatcaccact
    14521 aatagttcat ttttatactc acgtatataa ccaaacactg ctgaatcatt ctcattgatc
    14581 aatttatacg taccatgctg aatgattgga tagtttttac gcagtgaaat cagtttttga
    14641 taatgataaa aaactgaatt tggatttttt aaagcatctt ctacattgat ttgttgatta
    14701 tctggcgaaa aagagatcca aggatcactg ttcgagaatc catacccttt tgaatgatcc
    14761 caaggcattg gtgttcgtgc gttatcacga gatttcaaat aaatagcacg tttgatgtac
    14821 tcatcactct cgccttcttc tttcatcttt ttataaaaat agtttgtttc aatgtcttga
    14881 tactcatcaa ttgaagaaaa tggaacattt ttcattccaa tttcttcccc ttgaaaaata
    14941 aatggggttc ctttcatcat gtgaagtagt gttcctaaca tcttactaga ctctatccga
    15001 tattcgtttt catcaccaaa tctagtaaca gctcgcggtt gatcatggtt actccagtaa
    15061 agagaattcc aaccatctga aagcgcttct tgccactcac ttaacgtagc tcttaaatcg
    15121 ctaagcttaa accttacatc tgaaaacttt ccatactttc cataatcaag atgcatatga
    15181 tcaaaatgaa aaaccatatt taattcttta cgctcaggaa acgtataaag ctgtgcctgt
    15241 ctgctatttg tgttcggtgt ttcaccgaca gttaagctgt catatttact caaaacttct
    15301 cgattcatct cttgtaaaaa ttcatgcact cgcggaccgt tggatgctcc gacataataa
    15361 gactttgtat agggcatgct atttggagca tcaggataat caggatgctt gctaatcaag
    15421 ctgataacat ccattcggaa tccatcaatt ccaagatcaa accatttttt catcatttta
    15481 taaatagact gacgaacttt cgggttctcc cagtttaaat ctggttgttc ttttgcaaaa
    15541 caatgtaagt aatactgctt tctactctca acatactccc aagccgaccc gccaaatgtc
    15601 gatccccaat tcgtaggtgc actcccatct tctttgggat ctttccaaat ataataatca
    15661 gaatatggat tttctttatt tttttgtgat tctataaacc aagcgtgctg attacttgta
    15721 tgattgacga caaggtctaa aataactcga atattcagtt gatgcgcctg ttccaataat
    15781 ctcttaaaat cttctaacgt tccataattt tctgaaattt tctcatagtc tcgaatatca
    15841 tatccgttat caattagcgg agagtcaaaa attggagtta gccagataac atcaacccct
    15901 aactttgcta aataaggtaa tttttcaacg atccccataa gatctccgat gccatcattg
    15961 tttgaatcct tgaaactttg aggatacact tggtagacaa cactactttt ccaccattca
    16021 ttcatccgtt actcatcctc ctcatcaacg actatatttt ttaagtaatc attgacataa
    16081 accaattggt cttgtgcttc ttggattgcc tcacggatgt ggttgtctgt caatcttttg
    16141 tttaatgtat tcaataaaat tgtcaatacc acaggtagat tcatcccggt aatcagatag
    16201 acattaggtt gattgatata ttttataaat gcttgattga ctgaaccacc tagcatatca
    16261 gtaaaaatca atatatcagt atcctcattg tctcttacca ttacttcgtt aatcttttct
    16321 tctataggtg agttatcaat ataacctgcg attgcagtta tttcaccaac attcggtaaa
    16381 atatattgga cagtatcttt caatcctaca gctaaattat gatgactagc aaaaataatt
    16441 tttttcattc tttattctcc ttaaaccttt aaaataccga aaaatgatag aatcaatgcg
    16501 aatatgatca ctgaaaaaat aatttgaatg accgtcattt tttttgaagc tatcaattta
    16561 taaacaataa ttgttaaaac tgcaggtaag agtgctggca tgattttatc aagaatttct
    16621 gtttgaatag gtaattttac ttttccagat tgaaaaacca ctgcaacatt catttttaca
    16681 acagatggaa tcaaagctcc aacgactgtc aaacccataa ttgaagcaga ttctgtaaat
    16741 atcgataatt tacttcctaa agcagtcacc aactttaacc ctgaagtata cccaatcgaa
    16801 aaaagtttaa atcggaagaa caaaaagaat agattcaaac ataaccaaat aatggcacca
    16861 gtcggatttc cttctagacc catataagct gcaatcgagc ccataatcgt tggataaagg
    16921 acccaaacca acgtgtctcc cacaccagct aaaggaccca tcatcccagt cttaaaactt
    16981 tgaactgcat ctaatgaact gactccatct ttttcttcca ttgctaagct ggcacctaat
    17041 aataaattcg ccatccaagt cgttgtattg aaatatttaa aatggttatt cagagaagct
    17101 ctgtagtctt catcatttgg ataaattttt cttagtgctt tttcaagtcc ataaacaact
    17161 gccggacctt gttgattttc gtaattgaag atattacatg ccataaacat atagcgaaat
    17221 gctgctctac gtatatcttt ctttgataat ttatttcctt cattattcat caaaatcatc
    17281 tccttcatcg actatattgg cagctacagg tgatgccgtc tctgcttttt ttatttctgt
    17341 cgtgaaaaag taatacgcta aagcaaagcc gacgattgaa attcccaaaa taggcatgtt
    17401 taaataggcg gaaagtacaa aaccaatcaa gagcatcgtc atatattttt tcaccggcat
    17461 aacttgtaga agtaatgcta ttccgactac aggcaacatg cttccagcaa tcgataatcc
    17521 atctgtaaac cacttaggca caaaatctaa aatcaatcga acaattctat caccaaaaac
    17581 aacacacaat gcagttggaa tggctgtaga taatccgaaa atcactggtc ctaaccacaa
    17641 aatctgattc attttcttaa aatccatttt atttgctgcc ttttgtgccg catgagtaac
    17701 atatgtgttc aatattttag ccaacacatc taattgaatt cccagcatcc caacaggaac
    17761 acctactgct aatgcaacag cttttgcttc ttcaatatta tttgtggtac ggatggctac
    17821 gtagatacct acaagagcag ctaaacccca gttaggaacg gacgatcccc caatattcgc
    17881 tacacccaaa gccattaatt gaaacgtacc gccaataacc attgcggttg tcatatctcc
    17941 cataatcagc cctgcaaaca aagcaatcat gatgggaaac catgttgtaa tgaccaatcc
    18001 ttgttgatct aatacaaccc acactgctaa aataataatt aaaattcctt ggataatttc
    18061 cattccaatt atctccttta ttttattctc acatctaatg gttcttcagg atctgaagga
    18121 acaaaatgaa aagtaactgg tattcccata gcctctaatt tttttaaatc agcaatttct
    18181 tgttcatcaa ctgaaaccat tttttttact gtttgtttcc cttcaccatc aaacatgatc
    18241 ccgatattca cttttggtat atcgataccg ttctcagcta gttttactaa tgtactcggt
    18301 tcttttacga tcataagcac attatgactg tcatacttgc caagtttgaa attaataata
    18361 gctgtatctg tatcaataat tgacatcccc gttccagctg gcttactcat tcgcattgct
    18421 gctttttgtg tgtcatcctt actgacttga tcatctacga ccatcaatcg ttttgctttt
    18481 gtcgcacctg cccactgtgt taccacaata ccgtgaatca atcgttgatc gattcttgct
    18541 aatactaatc ccatatctat cgtctccttt tttgttatcg tttacatccc aaagtatatc
    18601 tacgccttgt tactttaaca atagttttag aagtatcagg gaaacagtcg ttatcttagg
    18661 aaatagtttc tttattaaga gaaatttccc acaaaaaaat agcccaacca tcgattagat
    18721 gactgagctc cctaaattta cgctatcttt tattactatt tacttctttt ttatcgcaat
    18781 ccaaatttcg ccatcacaat ccgtcaactc ttttgagaaa tcagtaaagg agagttctga
    18841 tgcttgaacc aactcatatt ctgaagttgg caaccactcc gcgtatattg acccgctgac
    18901 atccctaaaa aaggtgcgag gtggagaata tttttgatac aactatcctt atttatgata
    18961 tggagccccc gcattgatcc ggaaggcacg gtagatttgc tcgacaagga tcagacgcat
    19021 caattgatgt ggatacgtca tttttccaaa agagatgtga gcattgcttc ttttcatgac
    19081 ggcttcgctg agtcctaaag agccgccgat aacaaaaaca aggtggcttt ttccttggat
    19141 acctaattgg tcgatttgtt tagcaaaaga ttcgcttgtg ggatttttcc cttcaattgc
    19201 taaggcatag acgtattctt gttctttgat tttcgctaag atccgttccc cttctttttc
    19261 ttttacttgt ctcatttgcg cttcgcttaa attctccggg gctttttcgt caggaacttc
    19321 gatcaattcg atttttgcat aggcattcag ccgtttgaca tactcattga taccttggat
    19381 caggtatttt tcttttaatt ttcctactga gataattttg atattcatgt tttctctcct
    19441 ttggtcttca tgctcacttt gtttattata atcaattttt tcgtctatat gtttattttg
    19501 gctatttttg ttaaaaagat ttccccaaca gttatgcaca acatccacag gtttatccac
    19561 agaaaacagt gttattttac cttatttcat cacatttatt aggcaaacat acgttttata
    19621 agaatttatc cactttatac acaggctgtg gatatgtttt atcccttatt tttccaatcc
    19681 tatccgcgta gttttacaca gtttctgtgg aaaaaagcaa atcaaatatt ttcatctgaa
    19741 aacaatggtt tttcctaaag tttttcataa aaagttcaca gtctcaaagt agactaaagt
    19801 caacaaataa gagtatacta acagtagata aatgaatgta attggaggag gaacacatgg
    19861 atagaaaaaa tgtgacacca aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt
    19921 taggtctagg gcttgttgga gggatcgttg gaggattact gacagctggt attttttatg
    19981 cagcgatggg cactggcaac aatagttcta ctacaagtgg caatcaaaat tctgctggtg
    20041 aaacagttgt ggaaaacgtc aaagtcaatg tagattctga tatcaccaaa gcagtagata
    20101 aagttcaaga cgctgtcgtt tctgttatca acttgcaaag tcaaaaccaa tcaagcggtt
    20161 ttggcggact attcgggcag caagaagaaa gtagcagctc agatgatagt aatttggaag
    20221 cttatagtga aggaagcggc gtgatctaca aaaaagacgg gaatactgct tatgtagtca
    20281 caaacaacca cgtagtagat ggccagcaag gtcttgaagt cttgatgaaa gacggtacga
    20341 aggtaaaagc tgaattagtt ggaacagatg cttattcaga tttagcggtg ttgaagatca
    20401 attcagacaa agtcgaaaca gttgcctctt ttggtgactc aagtgctctg aaggttggtg
    20461 agcctgcgat tgcgattggt tccccattag gatctgaata tgcgaattct gtcacttcag
    20521 gaatcatttc ttccttgaac cgacaagtaa caagtacaaa tgaatcgaac gaaacagtca
    20581 atatcaatgc gatccaaaca gatgcagcaa tcaaccctgg aaattctggt ggtcctttag
    20641 tgaatatcga aggacaagtt atcggtatca actcaagtaa gatcgcaagt acttctgaat
    20701 ctacttctaa tgtaagcgta gaaggaatgg gatttgctat tccaagtaac gatgtagtga
    20761 atatcatcaa tcaactggaa aaagacggaa aagtgacacg tccagctcta ggtatcacaa
    20821 tggtcgactt atctgccgtt tctactcagc aacaagaaca aatcttgaag attccttcat
    20881 ctgtaactaa cggtgtcatc gtgacaaatg tccaaacagc tacaccggct gaaaaagctg
    20941 gattgaaaaa atacgacgtc attactaaga tcgatgacaa agaagtttct tctggtgtag
    21001 aacttcaatc tgctttgtat aagaaaaaag tgggagattc tgtcaaaatc acttactatg
    21061 aaggctcgaa agaaaaaaca actactgttg aattgacgat cgatcaatcg gcattaaaac
    21121 aaaatcaaaa tagtgaaaat taataaaaaa gaggttaggt tgtggcaaag acttgtcaca
    21181 acctaacctc ttttttataa actatatttt tcttgccaac tcctcggtca caagtcacaa
    21241 gatccaacaa acatgagaag ctgttttttg aaattgctcc ttgtgactca gagtgaaacg
    21301 gcagactcac aacctcttta ttttggaaat gcttctccga ctacggcatc ctcaggcaat
    21361 actaagattc ctttttttgc tggagcattt ggcaaatgca attcacgagc ggaacagatc
    21421 attccatagc tatctacccc tcgcaaagtt cctggccaga tcatcattcc atctggcatc
    21481 atagctcctg gttttgcaac gacaactttt tgtccagctt cgatattggg tgcaccgcaa
    21541 acgatttgca atactgtacc attgtctact tctgtctcag taatcgataa atggtcagaa
    21601 tcaggatgtg ggacgcatgt ttttacgtac ccgacaacga tcttcggttc atgatcagct
    21661 tcaagctgtt cttcgaatcc tgcttctttg atcaatcgat tcaatttcgc taattcctca
    21721 tctgttaagc ttacttggcc gttcccttcg attgttagat gatcggagat atggaaaaag
    21781 ttccaagcaa caacttgacc ttgttcatct ttgatccgag caacattcca tttgcgttca
    21841 acagtgtttt ctgttccttt atcgtcggct ataataacca tcaaggtgtc tccgacgtgt
    21901 gctttgttat aagcaaaaat catgttcttt cctccattat cctttgctga gatttatctt
    21961 aacaaaaaat tgcattcact gcatgagatt tttttcatgc tttatttccg aagaagcctc
    22021 ttctggaaca ccatttattc gtaacaaggg actgtgacaa gacttttgtc acagtccctt
    22081 tactgtttta gttaattgat taaaaaggtc gtacaagttc cacttgctta attacttggc
    22141 tgttcttctt cgtcagaaac gatcaagaca tcacaaggtg aatgacgtat cacgtagctg
    22201 gctacacttc ctgtcataaa gcgttcgact gcatttagac ctgactgccc aaccatgatt
    22261 agatcgatct catatttttt tggcaatttg actgccatgg attcacgaac agaaccatat
    22321 gcaataattc cttctatatt tgtgtaatca acagatttcc catattcttt acattcttcg
    22381 atcatttcct tggctgtttc agtttgctga tcgactagat tttgatcaat aggtgcatag
    22441 cccataaagt tataaaattg ctgatcgatt acgtttgcta catatacttt cccattatta
    22501 cggcgagcca cttccaccgc ttttttgaaa gcagcaagtg cttgttcact accgtcgata
    22561 cctactaaaa tgttcttata ttcttgattc atcttgaccc ctcctaacag atgtcagcct
    22621 tttgtcacac tttctaggaa cgattcgatt tcctgttttg ttttacgatc tttattcact
    22681 agacgaccta attcttttcc gtcttggatc acgacaaaac ttgggatacc aaaaatgttc
    22741 cattcagcgg ctacatctat gtacttgtca cggtctactt caataaattg ccaatcagaa
    22801 aagtcatttt caatttcagg catttgcggt ttgataaaac ggcagtctcc gcaccagccg
    22861 gcagtaaaga aaaatacact ctttccagtt tctacgtagc ctgctaattc ttctaaacta
    22921 tttgggataa tcattctttg tcctctactt tctgtttatg tatttttcaa ttaaattata
    22981 cacctttctt tcgaactaac aaacattgat cctcttttta taaaaaaaat ctggcaaaag
    23041 caatcttttg ccagatttta tagtttcact atcgcattat tttccgtata cgatcgtatt
    23101 cactgttgat ttatccaaac ctttcagtgt ttgtatcaac atttctcgtg cagcttcaaa
    23161 atcgcgaata ctgaacatcg tttgatgcgt atggatataa cgtcccacta cgccaatcac
    23221 tgtacttggg attccttcgt tttgtgtatg agcagcacct gcatctgtac cgccttttga
    23281 aacaaagtat tgataaggga tattgtttgt ttcagcgata tccagcaagt actcgcgcaa
    23341 acgaggaagc atgatcaaac ctggatcttg gatacgcatc aatgtacctt ctcctaaatg
    23401 tccgaatgtg ccatttttcg tcactgtatc atctgctgca gagcagtcta ctgcaaagaa
    23461 cagatctggc ttgaatttat tgacagaagc tttagaacca cgcaagccta cttcttcctg
    23521 gacattcgcg cctgcgatca atgtatgccc taatgtttca ttttgcaacg cttctaaagc
    23581 ttctaatacc attgtacagc catagcggtt gtcccatgat ttgctgatga tattctttcc
    23641 gttggctgtt ttgatcgttt cagcgtaagg aacgattgtg tctcctggaa ggacaccgta
    23701 actcattgcc tcttctcttg attcaaaccc agcatcgaac aaaatatcgg ttacttctac
    23761 tgatttttgt ccgcttgttc ctcgcaataa atgcggggga acggaagaag aaatacatgg
    23821 ataattctta ccagtagagg ttttaagtgt aaaacgctgt gcagaaacaa cgtaaggatt
    23881 ccagccgcct agaggtacga ctttaaaaag cccgttttct tggatttgtg tcagcatgaa
    23941 tccgacttca tccatatgtg ctgcgaccat tacacggggt gcatccgctt cttcatgatg
    24001 gcgcagacca aaaatgccgc ccaaaccatc taactgtaac tcatctacca gcggttccat
    24061 atgactttcc atataagcgc gaacatcttg ttcaaaaccg cttgttcctt gtaattctgt
    24121 taactctttg attcgttgaa atgttttttc ttccatatgc tattcgtcta aatttcagac
    24181 taaactcctc tcagacttat attgatctgc ggataaaata tgattttttc tgcagaccga
    24241 tcgtatttat tatagcttat tttttctggt agcggttatt tatttcaaag aaaatatgag
    24301 agtgtggtaa aataagcaca aggagtaaca agtgagaaga aggaggtatg tccacatgta
    24361 tgaagaaagc gaactaagct attttaaagg cgggttagca gttggaatcg gtctaggatt
    24421 attgagcggg gtagcttcaa cgatttggta tcatcgcaaa aaagtattgt cagcagacca
    24481 agtacttgaa aatatcaagt catcttttct aaaagaaggt gcaatcgaag gttcttggat
    24541 ctcttttgaa aaggaaccta ttaggaaatt cgccgttcgg tcgagtgctt atcggggagg
    24601 tctttctcga atagaagatg gcgaaactgt ttattatgaa tttttagcag atgctcatac
    24661 aggaaccgta ttagaaattt caagaaaaaa aggtgcaaca gattaatacg tcaaaaaagt
    24721 gagagaacga atacgcaccc actattcaaa agagaggtat cctatacttc ttttatagtg
    24781 ggtaattttt ataaaaatag ggctatttcc tcttggaata gctagtatta tagttattat
    24841 at
//
LOCUS       DAXLPQ010000037        24526 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.037, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000037 DAXLPQ010000000
VERSION     DAXLPQ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.037"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..1842)
                     /locus_tag="ACF3UO_001809"
     CDS             complement(<1..1842)
                     /locus_tag="ACF3UO_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657809.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            2054..2572
                     /locus_tag="ACF3UO_001810"
     CDS             2054..2572
                     /locus_tag="ACF3UO_001810"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3657810.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            2700..3383
                     /locus_tag="ACF3UO_001811"
     CDS             2700..3383
                     /locus_tag="ACF3UO_001811"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFD3657811.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            3692..3765
                     /locus_tag="ACF3UO_001812"
     tRNA            3692..3765
                     /locus_tag="ACF3UO_001812"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3726..3728,aa:Arg,seq:tct)
     gene            3924..4283
                     /locus_tag="ACF3UO_001813"
     CDS             3924..4283
                     /locus_tag="ACF3UO_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFD3657812.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            4406..6037
                     /locus_tag="ACF3UO_001814"
     CDS             4406..6037
                     /locus_tag="ACF3UO_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFD3657813.1"
                     /translation="MFKKYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(6099..6740)
                     /locus_tag="ACF3UO_001815"
     CDS             complement(6099..6740)
                     /locus_tag="ACF3UO_001815"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFD3657814.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    6926..7002
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            7022..7330
                     /gene="rplU"
                     /locus_tag="ACF3UO_001816"
     CDS             7022..7330
                     /gene="rplU"
                     /locus_tag="ACF3UO_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFD3657815.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            7357..7701
                     /locus_tag="ACF3UO_001817"
     CDS             7357..7701
                     /locus_tag="ACF3UO_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFD3657816.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            7714..8007
                     /gene="rpmA"
                     /locus_tag="ACF3UO_001818"
     CDS             7714..8007
                     /gene="rpmA"
                     /locus_tag="ACF3UO_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFD3657817.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            8441..11248
                     /locus_tag="ACF3UO_001819"
     CDS             8441..11248
                     /locus_tag="ACF3UO_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3657818.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            11439..11930
                     /locus_tag="ACF3UO_001820"
     CDS             11439..11930
                     /locus_tag="ACF3UO_001820"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFD3657819.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            12033..13022
                     /locus_tag="ACF3UO_001821"
     CDS             12033..13022
                     /locus_tag="ACF3UO_001821"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFD3657820.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            13055..13858
                     /locus_tag="ACF3UO_001822"
     CDS             13055..13858
                     /locus_tag="ACF3UO_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFD3657821.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            13879..14793
                     /locus_tag="ACF3UO_001823"
     CDS             13879..14793
                     /locus_tag="ACF3UO_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3657822.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            14876..15250
                     /locus_tag="ACF3UO_001824"
     CDS             14876..15250
                     /locus_tag="ACF3UO_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFD3657823.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            15389..15634
                     /locus_tag="ACF3UO_001825"
     CDS             15389..15634
                     /locus_tag="ACF3UO_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3657824.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            15806..16870
                     /locus_tag="ACF3UO_001826"
     CDS             15806..16870
                     /locus_tag="ACF3UO_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFD3657825.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            17116..17541
                     /locus_tag="ACF3UO_001827"
     CDS             17116..17541
                     /locus_tag="ACF3UO_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3657826.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            17534..17983
                     /gene="nusB"
                     /locus_tag="ACF3UO_001828"
     CDS             17534..17983
                     /gene="nusB"
                     /locus_tag="ACF3UO_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFD3657827.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            18080..18934
                     /locus_tag="ACF3UO_001829"
     CDS             18080..18934
                     /locus_tag="ACF3UO_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFD3657828.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            18935..20272
                     /gene="xseA"
                     /locus_tag="ACF3UO_001830"
     CDS             18935..20272
                     /gene="xseA"
                     /locus_tag="ACF3UO_001830"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFD3657829.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            20277..20501
                     /locus_tag="ACF3UO_001831"
     CDS             20277..20501
                     /locus_tag="ACF3UO_001831"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFD3657830.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            20503..21393
                     /locus_tag="ACF3UO_001832"
     CDS             20503..21393
                     /locus_tag="ACF3UO_001832"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFD3657831.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            21402..22220
                     /locus_tag="ACF3UO_001833"
     CDS             21402..22220
                     /locus_tag="ACF3UO_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFD3657832.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            22327..22776
                     /locus_tag="ACF3UO_001834"
     CDS             22327..22776
                     /locus_tag="ACF3UO_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3657833.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            22794..24476
                     /gene="recN"
                     /locus_tag="ACF3UO_001835"
     CDS             22794..24476
                     /gene="recN"
                     /locus_tag="ACF3UO_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFD3657834.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
BASE COUNT         7996 a         4064 c         5360 g         7106 t
ORIGIN      
        1 tacaggattc gggtaatttc gagagagttg aacagtgatc cgatcaatga aagtatcttt
       61 ttcctgcgtt agtgttcctg tgtaacgatc cgctacgtct ttcatcatca ttaagtcaaa
      121 acgttcctga tcatctaatt cttctgtgat gcctcgacta aataggtttg tatcgtaatg
      181 tgcactatgt tcgcaacaaa tgacgaaatg ttcctcttgt tcgtgtatcg acaaataaat
      241 ttttcgatac agtggatttt cgatggcatg agtttctcta aaggaatgct ctaaagcgtg
      301 gatcaaaagt tgagccagat cgtcatcgtt gataggaagt tcttcgggaa gatctgcttg
      361 gaaggttatc tgaatattcc gtttggcagc taacttctgg taacgcgcta agataagatt
      421 tgtcacctgg tggttgcaaa aagaacacag catttcgaaa ttttttgctt cttctaatat
      481 cttttccaca tagtttttag cttttgtttg gtccgtatgc attaaatctt gcagattctc
      541 catctcttgg acaaattcca ggcgaagtgt atttacttct tggatatgct gtcgaagctg
      601 ctcataatgt tgctccaaca aatcattttt gatttttaag aaatctactt gtctccgatc
      661 tttgtcggta tttaagatgt gatcgattag attgtagctg ataataacga ttagaatgat
      721 aatatataaa atcgtagacc aattgatcgt tgtttgatag atacctaatg ccgtttggat
      781 gtaaatcaag caatggataa tggctaccaa gacgatccaa ggtgtacaag ctacataaaa
      841 acggttattc ttatatgctt cgccaatgca tgcaagtgaa gtgactaaag tgcttataac
      901 actagcaata ttagcaatcg gcattaattc aggaagttct gcaggagtaa aagttgcata
      961 aagcagaacg ccgataaaaa tcaaaagttg gaacgtacaa aaaattccgt accatttttt
     1021 atagtaaaac attcggctcc aatagtagca gatgatgaaa gctgacgtta agataataaa
     1081 taaatgagat aaaaaagaat gaacgaatgg ttcaaaaaga ataccactta aaatatcttc
     1141 tgatacagct tcaaatccta atgccaaagc aaagcaactt aagagaataa gtgagtattc
     1201 aagacgtttt tgtttataca tcaagtagat cgtatagaaa aaggtcccta tagcgataaa
     1261 aacagcgatt atcatcgtca atacttgcgg cactgattgt gaataaataa aactaatcaa
     1321 tggtccagtt gttcctagat aaactttcgg tggcagtcca gcatagttct gataaggaga
     1381 tgagactgta agggtcaatt tttttccgat ataatttgct ggtaaatcta tcacagccaa
     1441 tgagagtccg ggattgcttt cttcctgata atctttccgt tggtataaaa tcttttcgcc
     1501 tagatataca gtaatccatt gatggtttcc tttgattagt aaatttgctt cgtccaacgg
     1561 tttttcaagt gtcgtttcca taatgaatgt ttcgtcttta tccacggtag gaatcgtacg
     1621 agtgtacttg ctgtcaaact taaaatcagg atcatctttt gtatagaaaa cccacgaatc
     1681 ttttatttct ttcatttgat tgctgtccgc aggagaaaaa ataaaataaa agaaataagc
     1741 aattcctgtt aaaaataaca atgataatat aatgattatg ctccacttta tacgtaaata
     1801 aaaagattct tttttattat atatgttatt aaaaaaagac ataaaggtat tcctttctaa
     1861 aacttgtaat gttagggtaa acgtttttta aactaacgtc aattatttat aataaaaaat
     1921 gagataaaga tgaggaaata gaattagaaa catataatta ttaaagggaa acatttttac
     1981 agctataatt tgaaaaaaat ttatcgttat tatatgatta agaaggattg aataaagaaa
     2041 gaagttgaaa acgatacctg attacaaaaa aataactttt ataagttcta taacgttgat
     2101 tatattttta attcttattc ttctcgtcgt cttggttccc cgaatttttg gtttgactcc
     2161 ttatattatt gaggacaaag aaatgagtcc atattatgca caaggaaatc tgatatatgt
     2221 acgaccgaaa aatacaaatg agattttagt cggagatatt attacatatt atgaaaattc
     2281 aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa aacaaccacg aagattttta
     2341 tacaaaagct gatacaaaga cttatattga gcctggagta gtaaaaaaga gaaatattat
     2401 cggtagtccc atctttcaga ttccatatat tggactagtc ctttcaaaaa cggcatttgc
     2461 atggattcag gggttattct ttacgattgc tttttgccta acaggaatca cagcatggaa
     2521 tacctttgta gagttgaaaa agaagcggag acgaacacag aaatttttgt aagaatgtta
     2581 aaaacataaa tgtattccag agatccaacg actcttctga acatgaaaca cgagaaaaca
     2641 ctcatgcagc ttgtagattt agtcagttgt tcgtataatg tgtgaagagg aggagtagta
     2701 tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga actattggat tttatgcgta
     2761 cccagcaaaa aaaattaccg ggtgagctag gcaaactgga agaagaagct catgtagcag
     2821 aagtaccagt tattccccat gaaacagttg tatttttgaa atttttactt ggacagcttc
     2881 agcctgaacg aatcttggag atcggagcag ctatcggttt ttcatcaagt gtcatggcca
     2941 cgacaatcgg agaaaacgct catgttacga caattgatcg tttcgatgtc atgatcgaga
     3001 aagctaaaaa aaactatgaa cgtctaggac tgacagataa agtgactttg cttgaaggtc
     3061 aagcagcaga tatcttgccg gagttgtctg gtccgtatga ctttattttt atggatagtg
     3121 caaaatcaaa atatattgaa tttttacctg aatgcttacg tttgttaaga aaaggtggcg
     3181 ttttgatggt agatgacatc ttccaaggag gaacgatctt gctcccagat gaagagattc
     3241 cccgtggcaa acgagctatc catcgtaaat taaatgaatt tcttcgtgtt gtgatggatc
     3301 atcccgattt gacatcgaca atcttgccat taggtgatgg tgtgatctta atgacaaagg
     3361 aatcagaaac aatcgagttg tgatacatga ttatggcagc ctgtagataa tcgattgaat
     3421 cgagggctca attcgaactt gatgtaaaag tttctatatt tgtaagtcaa ttaaaggata
     3481 caggaaatct aaataaacag gagtagcatg aagtcaatgt agctcctgtt ttcaattgat
     3541 aaccttagaa cagctgaagg agaatgtctc gttttaaaag attgatttag tagttgggcc
     3601 aaaataattc attatttgct aattaaataa ctatttcgta ttgacagaag caatttaatt
     3661 atctataatt attgatgttc cgctgattct tgtcatagta gctcagctgg atagagcatc
     3721 cgccttctaa gcggacggtc gggggttcga atccctcctg tgacgctaaa aaaccgttag
     3781 aaactgaggt ttctaacggt ttttctttgt tttttgtgcc aatattgttt gttttcaaag
     3841 gcaaataaaa taaaaaaaca tccttatcga gtacaattat aaggagcaaa aaaataaaac
     3901 tcatcagaaa agaggaagaa gatatgacga tactatctag aattttagtg actctagttg
     3961 caattgaatt tttttatatc atgtatatcg aaacggtgag aactgattct gacacgacaa
     4021 gtagggtttt taaaatgagt aaagaagagt taagcagaaa atctgttcaa acattgttta
     4081 agaaccaagg agtgtacaat ggactattag gagtgggact actttatgga gcttatcttt
     4141 cttccgcatc taaagaaatc acaagtatgc tattaatatc tatttttttt gttgcattat
     4201 atggcagttt gactagcgat cgttggattt tactcaaaca aggtgggcta gctctgttgg
     4261 cattgctttc tattttctta taaatataga aaaaataaga atttatctaa caggaaactt
     4321 tgtgaaaaat attactttat ctcatgaaat atgatattct aatgaatggt attttagaaa
     4381 atttcatgaa aaaggagtta gataggtgtt caaaaaatat gtttcctcac taaaaaaaga
     4441 attttcaggt tatgatcttt caagatttca gaaagatctt ttggctggga tcacagtagc
     4501 tgctgtagca ttgcctttag ccttggcttt tggggtatca agcggagctg atgcggccgc
     4561 aggtttgatt acggctatca ttgccggtat cgttattggc ggtttatcag gcggttttta
     4621 tcaaatatca ggtccgacag gtgcgatggc agctatcttg atgtctattg cggcaacaaa
     4681 gggaatgcaa ggtgtattgc ttgctacttt tttagcgggt ctatttttac ttgcagcagg
     4741 acttttccga ttaggaacac tgacttcttt tatcccagca cccgtaatta cggggtttac
     4801 ttcaggtatt gctatcatta ttgcattagg tcagatcgat aatttatttg gtgttcactc
     4861 ggaaggtaca aacgttattg aaaaactaag tagttatcaa acgataggat ttccgataaa
     4921 cacagcctct ttgatcatgg gagggctagt cattttaggg atgtttatct atccaaaaaa
     4981 atgggcgaaa cgaatgccta gttcgctgct ggctatcatt ttggcaacag cagttatgct
     5041 attgttccat ttaccagtag caactgtggg taagattcca caaacattga tcagtagtaa
     5101 tcgtttgaat atgggagatt ttagcttttc tgccttgcaa caagtggcag ttccagctat
     5161 tagcattgct ttattaggaa tgattgaaag cttgctatgt ggtgcttcgg ctggccgaat
     5221 ggcaaataag cccttagata gcaatcaaga attaatggcg caaggaattg gaaatctgtt
     5281 gcttcctttc tttggcggga ttcctgctac tgcggccatc gcccgtacaa gcgtggccat
     5341 caaatctggt gcacaaacta gattagctgg tatgatacat gcagttgtct tactgctctc
     5401 catgcttgtt tttgcgccag tgatgtcaca gattccaatg ccagcacttg caggtgtttt
     5461 gattgtgacg gcttggcgta tgaatgaatg ggaaacgatc aaggagctat ttactaataa
     5521 atattggtca gcagttctat tgtttatcct tacgatgatt tgtacagtta tctttgattt
     5581 aagtattgct atcgtgatcg gggtgatcgg cggctgtgta ttttttgttg tcaaaagcgc
     5641 tgctatcacg atttcattag aaacgatcga ttggcaaaga atggggctgc cagaaacgga
     5701 aaagctgaat aactggacag tagtgtatat tagtggtcca ctgtttttta tgtcttcaga
     5761 aaaactcaaa aataaattgg aagaactaaa tcatcacgat ggtgtcattt tctccatgcg
     5821 aggcgtacca agtattgatt tgacggcacg tgcagttttt gatgaatttc aagaaaaagc
     5881 agagcaaaga ggacaaacga ttatctatac ttccttgcag ccagaagtag aaaaacaact
     5941 ttctcacttg tgggaacata cattcacgca tcaacatcaa acagttgctc atgcgttgac
     6001 agctttacat gcgaaatata ctgcaattag ccattaaaac aatgaaaaag aacagacaag
     6061 actgtaaact gaagatttta tggtcttgtc tgttcttttt aatattgctg taaaagtgaa
     6121 gctagtactt gccagtcttg atggataaca ggtacaaggg agcgattgta gaaaatagct
     6181 gctggatgaa aaagtggaag aattcgatag tttttttctg accattcgta ggcatccttt
     6241 tgttctgtta attgtaagac aggccctgta tagagttgac catgattttt ggtaaccgta
     6301 tattctttgc caagtaaacg ttgaagacca atgtttccaa gtgtcgcaat taattttggc
     6361 tggaccttca tcagttcgta atccaatatt ggtgcatgcg caaatacttc ggaacgagta
     6421 ggtgtccgat ttggataaac agtttctgac tgttgtgtcc gtttattgat ccgatgagtc
     6481 acgcgatacg ggcggctcct tacagcactg gtgatataca cctcttctcg tgttaagcca
     6541 gttgaagaaa gtgcctgcat caattctttt ccagcttgac cgctaaaagg aacatgcgta
     6601 tcaatctctg ttttccctgg ggcttctccc acgagcatca gtttaggatg aagaggtcct
     6661 tgcccagcga taaatccttc tacaggacgg ccgttcattc ttaaagaagc ttcttgtatc
     6721 agttcttttg ggtattccat ttatgctcct cctttttctt ttattataag aataaaagaa
     6781 acacaatgcg actattttat ttggtagaac tgtgaggata gaaaagcaga agtattgctt
     6841 gaatttttgt tttacttttt gattttaaat ttagttgact aacggttgct gttctggtaa
     6901 gctagtactg ttgtaattgt ggactccaca gctacaaccg ctcagaacaa gtaataagca
     6961 cagcatatgc tgtcacttcg gatggcgagt ctaagtatat gagaaggagg tgctttatag
     7021 catgtacgca attattaaaa ctggtggtaa acaagtaaaa gttgaagtgg gacaagcaat
     7081 ctatgttgaa aaacttgacg ttgaagcagg agaaaaagtt gtttttgacg aagttatctt
     7141 agtaggcgga gaatctacaa aagtaggcgc tccaactgtt gcaggtgcaa ctgttgaagg
     7201 tactgttgaa aaacacggca aacaaaagaa agtcgttact ttcaaataca aacctaaaaa
     7261 acattcacac cgtaaacaag gtcatcgtca accatataca aaagtggtta tcgacgcgat
     7321 caacgcttaa tagcgtttga gaaagaaggc ctatatatga tcaaaggaac atttaagcga
     7381 aatgacgcag gtcagatcgt ttcattcact ttgaccgggc atgctgatgc tggtccttat
     7441 ggaagtgata tcgtttgtgc gggtgtttct gcgttagcga tcagcactgt caacgggatt
     7501 gcctcattag ccggttttga gccgattgtt gaaatgaatg aagaagaagg cggttatctt
     7561 tataccgaag tcacttcagg aatgacacaa gaacaaaaca atattgctga gattctatta
     7621 gaaaatcttt tattaggatt acaatcgata gaagctgaaa actcagaata tatccaaatt
     7681 aaaacaatta atgataaata ggaggtgcag accatgttgt tatctatgaa tctacaatta
     7741 tttgcccaca aaaaaggtgg cggttctaca tctaacggcc gtgactcaga atcaaaacgt
     7801 ctaggtgcta aacgtgctga tggacaaaca gttacaggtg gatcaattct ttaccgtcaa
     7861 cgcggtacaa aaatctatcc aggtgtaaac gtgggtatcg gtggagacga cactttattt
     7921 gcaaaagttg atggcgtagt acgtttcgaa cgtaaaggcc gtaacaaaaa acaagtgtct
     7981 gtttatccag tagctcaaga agcttaattg aatcttatga ttaaagaggt tgtgacaaga
     8041 cttttgtcac agcctttttt gtttataaaa ataaaagttg tagtggaggc tacgaagttt
     8101 actttgtctt tttacactta atattttttt gccaatttgg aatcaggatg ttttgataac
     8161 tatcgttttc aattgatgga agctatattg tttgctatca gtgaaataat tatatggtaa
     8221 acagtgttct ttttcttgtt tccattataa aaatcgtatc gggatttttc gttcttttaa
     8281 attgaacatt tctatctatc cgcgtgttat caacaaaaca aaatcaggta aatagttgac
     8341 gaaacagaaa taaatacata gtattatgtt ttgaagccta agtacaatag tctatagaaa
     8401 aggagcgata ccattggcaa aacgcattga ccgaatttat atgtatgtca aagaaaaaac
     8461 cgctcattta acaaaggcag aatatgatca aggagtaaca acacaggaaa ttgctgaagt
     8521 gttagggatt cagcgaacaa atagcagtaa agatctgaat cagctagtgc gcgaaggaaa
     8581 actgataaag acagacggac gaccagtacg ttacatatat caaacactcg ttacgcacgt
     8641 aaagccagtt acaaaacatg tagtcagtta caaagaaacg ccggtctctg aagaaaaaaa
     8701 tacactccaa atagatacta aggatatctt tgcaaaaatc attggagcta acggcagcat
     8761 gaaaaattca gtggaacagg caaaagctgc gattttgtat ccgccaagag gattaaattg
     8821 tttgattaca ggacctaccg gatcaggaaa gacttatttt gcacacgcga tgtatcattt
     8881 tgcaaaagcg catcatgtaa tagatgagga aacggaactg attgttttca attgtgctga
     8941 ttatgccaat aaccctgagc ttttgatgag tcatttattt gggtacgcaa aaggtgcttt
     9001 tacaggcgca gatgaagaaa aaatggggat tatcgatcaa gcggatggcg gtatgctgtt
     9061 tttggatgag attcaccggt tgccgcctga aggtcaagaa atgatctttt actttatgga
     9121 tcatggaact tacagtcgtc ttggggaaac aacgaaatcc catgaagcaa atgtacggat
     9181 cgtaggtgcg accacagaag acccaggttc ttctctatta gaaacttttg ttcggcgtat
     9241 cccaatcaat atcaaacttc cggcttttga aaaacgtcct gcaaatgaga aagtcgattt
     9301 agtaaaaatc atgattgccc acgaagcaaa ccgcacgcag cgaaagattt ctttgacaga
     9361 agatgtagca aaagcattga tcggcagtgt gacctatgga aatataggac aattgaagtc
     9421 aaatatccag ttagtatgtg cacgaggatt tctaaatcat atgcaatcac ccgaaatctc
     9481 gatcacaatc gatgatttga cagaagggat tcgtagcgga ttgattcaat tagcaagcaa
     9541 ccgcagtgca atggcagagc tttctaaaat attggagcca aagataactg tagcaccaaa
     9601 tgatacgatc atgaaaatcc aatcggactc ctatgagtta ccttataatc tatatgatat
     9661 catcggagat aaagcagctt tactgaagtc ggatggtttg gatcaagaag caatcaatca
     9721 tttcatttct acagatatca acatccatct gaagtctttc tataaagacc atggtttttc
     9781 ttttaatgca gacagcaaat tagcagaatt tgtagatccg aaaatcatag aagtgaccaa
     9841 tcagatttat gtaatggtca aaagatcttt accatatgag tttcagcaaa actttattta
     9901 tgctatgagc ttgcatatca gttctttttt gaaaaaaatc aacttaggag aagaacggca
     9961 tacgaatgat aacatccgtg agatggcttt tgattttcca gatgaatatg ctgttgcgaa
    10021 agaagtgcgt agttatatcg aaacgtattt tcaagtggag attccagaaa gtgaagacta
    10081 ttacttgacc gttctactcg tctcgttacg ggcaaatcaa gcaagcggca gaatcggtgt
    10141 agtcgttgca gctcacggaa acagcacagc aagcagtatg gtccaagttg tccaacagtt
    10201 gttagatgca gagaacgtac gagcagtaga catgcctttg gatatggatc cgaaaacagc
    10261 attggaccga attgaacgca atgtacaaga agtagatgaa ggaagcgggg tcatactctt
    10321 agtagatatg gggtcccttg cgtcgtttaa ttcgcaaatt caaagagaca ctggaattcc
    10381 agtacgtact gttgatatgg taacaacttc tctagttttg gaaactgtac gaaaggtctc
    10441 agtattaggg acagatctag atatgttgca tgaatcattg aaaaattttc gaggttacgc
    10501 agaaatatct tctgtagaat ctgttcagga agcaaaacct attcataaga aaaaagctgt
    10561 tttggctatc tgcgcatctg gcgaaggtac agcacaaaga atcaaagaat tgatcgaacg
    10621 agcggtaaac aagcgtcaag aaacagaatt agaagttcta gctttgtcga ttgtggaagt
    10681 gaaagaagaa ctgccagtta tccaaaaaga atatcagatc atagctacta ctgggattac
    10741 tgatttgaat atccaagccc catttattcc tttagaacgt tttattgatc aaaatatcga
    10801 agtcattttg gatcagttgc tgatggaatc agaattggag gaaactgaat tcatctccct
    10861 agatgaagag tcagctaaaa atacgtgtgt tgagtttatc tctgataact tcatctttat
    10921 taatggtagt aagttaatcg atccaatgtg gcaattttct acacaaatct ctcagacgac
    10981 gggaatcggc gatgaagaat atggattcaa aatcaaccta gtgatgcaca cagcaggaat
    11041 gatcgaacgt attattcgga atgaaccatt gactgtggaa gaaaacgaat tgacaaatac
    11101 aacgaatgat cctctttata gccaattggc agcctcagtt gttctgttgg aagatcagat
    11161 aaaagtaaaa gtgccgatag aagaaatgta ttatctgcta cgtctagtcc ataatcagtt
    11221 agataaaaaa gaatacactg tgccatgaat acacaaaaac gatacacttt tatagtgtat
    11281 cgtttttgtg tattggttaa gaatccttta aattcaatta gtgtatcgta aaaaagttgg
    11341 cacgcttttt gcttatagta gtgtgtgcta ggaggtggtt gttcacacag aaatgatagg
    11401 ggtttctgtg aagtagtgag gaagaaggag ttttgcagat ggatattcga ttggcacgta
    11461 tagatgatcg tttaatccac gggcaagtcg caacagtttg gtcgaagcaa acaggtgttg
    11521 aacgtatcat tgtgatcagc gatgtagtcg ctcaagataa attgagaaag tttctactaa
    11581 aagaagctgc accgccgggg atcacagcaa atgtaataac cgtgcagaaa atgattcaaa
    11641 tctatcatag tggattatta tcacgagcaa aagtgatgct tttattcacc aatccccaag
    11701 atgttgaagc ggttgtccgc tgcggtgtac agttgaagtc gttgaatatc ggcggtatga
    11761 gttttactga aggcaaatca atgattacca attttgtttc agtaaatcaa caagatattg
    11821 attcctttcg ttacttgaac agtcaagaag tggagttaga gattcgaaaa gtacctgctg
    11881 acaggaaaat ccttttgatg gaactactag cgaaaatcaa aaaggtgtag caagaatggt
    11941 tgttggaaaa ggtcaaataa ttctgttgta atggttagca attattaata tttttgaatt
    12001 tgttacaaca aaagtaaata ggaggtataa atatggtagg gattatccta gcaagtcatg
    12061 gacaatttgc tgaaggaatc ttacaatccg gttcaatgat ctttggcgaa caagaaaacg
    12121 tcaaagccgt gattttgaaa ccaagtgaag gtccagatga cttgagagcc aaattggaag
    12181 aagcggttgc ttcttttgat aatcaagacg aagtgttatt cttagttgat ttatggggcg
    12241 gaacaccgtt caatcaatca aacacattat tcgaagagca caaagataaa tgggcaatcg
    12301 tcagcggttt gaatttacca atgttgattg aagcctacgc atcacgcttt tcaatggaat
    12361 ctgctcatga aattgcagca cacatcattg aaacagcaaa agacggtgta aaagtaaaac
    12421 cggaagaatt agaaccggca gaagcaccga aagcagcagt tgaagacgca caacctaaag
    12481 gagcacttcc agaaggaact gtggtcggag acggaaaaat caaatatgta ttagcacgtg
    12541 ttgactcacg tctgttacat ggacaagttg cgacagcttg gacaaaagca gtgcaaccaa
    12601 accgtattat cgttgtttca gatgcagtat caaaggatga tctgcgtaag agactaatcg
    12661 aacaagctgc tcctccaggt gtaaaagcaa atgttattcc tattagcaaa atgatcgaag
    12721 tagcaaaaga ccctcgtttt ggaaatacca aagcattgct tttatttgaa aatcctgaag
    12781 acgtattgac agctgttgaa ggtggcgtag acatcaaaga attaaatgtt gggtcaatgg
    12841 cgcattcggt cggtaaagtc gttgtaagta aagtattgtc tatgggacaa gaagacgttg
    12901 aagcgtttga gaagcttgaa caaaaaggtg tgaaattcga tgtacgtaaa gtacctaatg
    12961 attcacgcga taacatggat gatattttga aaaaagcaaa agctgaatta gcaaaagcgt
    13021 aataaataat attaaaattt ataggaggct tatcatgtct attatttcaa taattttagt
    13081 cgtattagtt gcctttctag ctggtatgga aggtattctt gatgaatttc aatttcatca
    13141 accactagtg gcatgtacat tgatcggttt agttaccggt aacctcgaag ctggtatcgt
    13201 acttggcggt acgcttcaga tgatcgcttt aggttgggca aatatcggtg ccgctgtagc
    13261 accagatgct gcattagcat cagtagcatc agcaattatt ttagttttag gtggacaagg
    13321 tgttaaaggt gttccttctg cgatcgcgat tgccgttcct ttggctgttg cagggttgtt
    13381 cttaacaatg atcgtacgta caatcgctgt tccaatcgtt catttgatgg atgcggctgc
    13441 tgaagaagga aacatccgta aggttgaaat gtggcacatc attgctgtat gtttacaagg
    13501 ggttcgtatc gcggtcccag cagcagcgtt gctatttatc ccagcacaaa ctgtgcaatc
    13561 attccttgaa tcaatgccag catggttaac agatggtatg gctatcggtg ggggaatggt
    13621 cgtagctgta ggttacgctt tggtaatcaa catgatggct acaaaagaag tatggccatt
    13681 cttcgttatt ggtttcgttg tagctgcaat ttctcaatta acattgattg ctctaggtgc
    13741 tttaggtgtt gcattagctc ttatttactt gaacctttct aaaatgggtg gttcatcaaa
    13801 taatggaggc ggaagcaact ctggtgaccc tttaggcgac attttgaatg actattaatc
    13861 ttgaaggagg aaaataaaat ggcagaagaa aaaatcaaat tatcaaaaaa agatcgttta
    13921 gctgttgcgt ggcgctctac cttcattcaa ggttcatgga actacgaacg tatgcaaaac
    13981 ggtggctggg cattttctat gattccagca atcaaaaaat tatacaaaac aaaagaagaa
    14041 cgttctgcag cattaaaacg tcacttggaa ttctttaata cacacccata cattgcttct
    14101 ccaattttag gggttacatt ggctctggaa gaagaacgtg cgaatggcgc gcctgttgat
    14161 gatgtagcga ttcaaggggt taaagtaggt atgatgggtc ctttagctgg tgttggtgac
    14221 ccagtgttct ggtttacagt acgtccaatg ctaggtgcac taggtgcttc attagctatg
    14281 ggaggaaata tccttggacc aatcatcttc ttcttaggtt ggaacattat tcgttgggca
    14341 ttcatgtggt atacacaaga atttggctac aaagctggtt ctaaaattac tgatgacctt
    14401 tctggcggat tgttacaaga cgtaacaaaa ggtgcttcaa ttttagggat gttcgtatta
    14461 gctgcccttg tacaaagatg ggtatcaatc aaattcttac cagttgtatc aactgtaaaa
    14521 ttagataaag gtgcttacat cgaatgggat aaattgcctt caggtggtga aggaatcaag
    14581 agtgcatttg aacaagttaa taatggctta gccctttctc ctgaaaaggt aacaacatta
    14641 caagacaact tagaccaatt gattcctggt ttagctgcat taggattaac attgttatgt
    14701 atgtggttgc ttaagaaaaa ggtttctcca atcgttatca tccttggttt attcgtagtc
    14761 ggtgttgttg gacacgtcat cggactttta taatccataa aaatatagct cgggcgttgt
    14821 cccgagcttt ttttatatag tatactgttc ataaacaaat atctggaggg agaaaatggt
    14881 tcaatcaatc aatacaaaag tagacttggt aattgatgct acttcgttta cgggtctgac
    14941 agattacggg caaatcatga taggtgataa tggttttgag ttttaccatg cgcgagatag
    15001 acgcaaatat atccaaattc catgggaaga agtggattat gtactagcat cagtcatgct
    15061 aaagggaaaa tggattcctc gatatgccat tcaaacgaaa aaaaatggta catacacatt
    15121 ttcttccaaa gaacctaaaa aagtgcttcg tgcgatcaga gaatatgtag atgaagatag
    15181 aatggtacaa tcattgagtt tctttgatgt agtgaaacgt ggtattcgta gtatgtttaa
    15241 acgcaagtaa aaaataaaga aaacttctaa gaggaggttt tctttatttt tttactttgc
    15301 agaagaaaat atgaaatagc aaaaccaatt atttgtcccc tttaaatccc atatgctaaa
    15361 attgattagc aaagaaggag gttatattat gagttggtta tggacattga ttgttggagc
    15421 cgtgatcgga gcaattgcag gtgcgatcac cagtaaagga aattcgatgg gctgtgtaac
    15481 gaatatcatt gctggactag tcggttcaag tattggacaa gcgattttcg gcgaatgggg
    15541 accaaaagct gcaggtatgg cacttattcc atctatttta ggcgcagtga ttttggtagc
    15601 agttgtctca tttttctttg gaaaacgatc ataagttttt acaaaatagt aaactaaaag
    15661 gagttgcagc gagactgtga ctcctttttg gctttattta tttaaaataa aaagaagttt
    15721 tccggaaatt tttatttaac tgtcgtgtac gaagaaaagt ttgctataat ggaaaaaagc
    15781 gtgcaaagaa agagggagtt tcattatgat gctacgtgta gaaaaattgc gcaaaaaaat
    15841 gcaagaagaa aatttggatt catttttggt taccagtccg tacaatcttc gttacttaac
    15901 gaactttaca ggtacgacag gattagctgt tattactttg gaaaaagcat tttttattac
    15961 tgattttcgt tataccgagc aggcggcagc gcaggctcaa gggtttgaaa ttattaaaaa
    16021 tgtcggacct atttttgatg aggtagcaaa cttagtacgc aaagaagaac tgcactcatt
    16081 agcttttgag gaaacaacag tctcattttt agaatattcg gttttagaag aaatcatcga
    16141 tgcggaatta gtacctgttt cacagatgat cgaagaactc agagaagtga aagatgaaga
    16201 agaaatcgct attatcgaaa aagcatgtca tattgcggat atggcatatg atcacatcct
    16261 gaaaatgatc caaccgggca tgactgagat tgaagtcgca aatcaactag acttttatat
    16321 gcgttctctt ggcgcttcag gtgtttcttt tgatacgatc gttgctagcg gattgcgttc
    16381 ggctatgccg catggtgtag caagcaaaaa aatcatcgaa caaggtgact tgatcacatt
    16441 ggactttggt tgctattacg aagggtacgt ttccgatatg acacgtacat tcgctattgg
    16501 tgatcctggg gaaaaattaa aagaaattta tcaaatagtc ttagatgctc aattagcagt
    16561 tattgatgct gcaaaaccag gaatgactgg tgtccaatta gatgcagttg ctagagatta
    16621 tatttcaaaa catggttacg gggaagcatt tggacattct acaggacatg ggatcggttt
    16681 agagatccac gaaggaccaa acgtttcttc tcgtgcagaa aagcaatttg taccaggaaa
    16741 tgtgatcact gatgaaccag ggatctactt accaggaatc ggtggagtac gtattgagga
    16801 tgacttgttg atcacagaag atggaaatcg tgtgttgact cgttcaccaa aagaattgat
    16861 catcttatag tttcatcaat agaagaagta agcgtaaaaa tcagtgttca cagactttgt
    16921 tatagaaaat cactcgattt aatgatacac tatagaagaa cttttaagct gtaagagata
    16981 ataaagttgg gtgttttctc caattcatag cagtttgcag ctgatcggcg gcagttttct
    17041 taccacgtga tcactatgcc gcatcataga gaattcggat gtatctcgtg cttaggcaaa
    17101 gggaggaata aataaatggc agatgaaaaa aatttgattt taaacgcaaa ccaagattta
    17161 ggagagatcg tgatcgctcc tgaagtcatc gaagtaatta tcgggattgc agcttctaaa
    17221 gtagaaggcg tatacggaat gcgcggaact tttgccagca atgtcactga attattagga
    17281 cgtgcagctc acggaaaagg tgtttactta gcaaacgagg aagatggctt gaaagtagat
    17341 ctttactgtt atctagaata tggtgtttca gttcctaaag tagcaatgga aatgcaggaa
    17401 cgggtcagcc agcaagtcct tttcatgacg gatatcgatt tatctgaagt caatatccat
    17461 gtagtagctg ttgttcctga aaaattagaa caaccaacaa tcgaagaact ttttgaagac
    17521 gaagaggaag agaatgaata aagaattatc aagacacgag attcgggaaa tggcattgca
    17581 ggctttattt ccattagact tcaatgcaga cctaacaaaa gaagatgcga ttttcaacgc
    17641 aatcgaatta gaccaccgcg acatgatcaa cgaagatgaa tcagagtttg ttcctgttta
    17701 tcttgatacg ctagttggcg gtgtctgtgc aaaaaaagat gaattggata aagtgattga
    17761 aaaacattta aaaaacaatt ggcacatcaa tcggatctca aaaatggatt tggtgatctt
    17821 gcgtatcgcg atttttgaaa tgacttatgt gacagatgta ccagcggctg ttgctttaaa
    17881 tgaagcaatc gagttggcaa aaacatttag tgatgaccgt tcacgtaaat tcgtcaacgg
    17941 tgttttatcc aatgtattga aagaattaga agctggggcg taagtcctag cttttttcta
    18001 tgaatcatca taaacctgtt ataaatcggg aaaattctat ggtagaatga aaacacaaaa
    18061 aatatctggg agtggttaga tggcagaatt gattaacgga aaagaattag ctgaaaaaat
    18121 gcaggcagag attgctgaaa aaatccaaaa attgaaagat aatggtatcc atcccggatt
    18181 agtcgtttta ttggtagggg aaaatccagc cagccaaatc tatgtaagaa ataaagaacg
    18241 tgtagcaaaa gaaatcggaa tccattcatt ggtagagcgt tatcctgaga cgatttctga
    18301 agacgaacta cttgcagaaa ttgaaaaata caatcaagat cctagttttc atggtatatt
    18361 ggtccaatta ccattgccaa agcatataga tgaagaaaag atcctgttag ctatccgccc
    18421 tgaaaaagac gtagacggtt ttcatccgat gaatttaggc agactccttg cgggtaaacc
    18481 ggacaagatt ccttgtactc catacggcat catgaaaatg tttgaagctt attctatcga
    18541 tccggcgggt aaacgagcag tagttatcgg acgaagcaat atcgtcggta aaccgatggc
    18601 tcagctactc ttgatggcag atgcaactgt tactgttgct cattctaaaa ccgaaaatct
    18661 ggctgaactg gcacaagaag cagatatttt agtcgtagca ataggacgtg gacattttgt
    18721 cacaaaagaa ttcgtaaaac caggtgctgt agtgatagat gtagggatga atcgtgatgc
    18781 taacggtaag ctgatcggtg atgtgaaatt tgatgaagtg gagcctattg caggctggat
    18841 cactcctgtg ccaaagggtg tagggccaat gactatcacg atgctgatgt atcaaaccgt
    18901 aaaatctgcc gaagcttttg gagcaggtga atagatggca caagaatatt taactgtcac
    18961 tacattaacg aagtatttga aaagaaaatt tgatgccgat ccttatttag aacgcgtata
    19021 tttaacaggc gaaatatcga atttccgttt acgtgccaat gcccatcaat atttcagctt
    19081 aaaagatgac catgcaaaaa tatctgctat tatgttcaaa ggagcattcc aaaaattacg
    19141 attccagcca aaagaaggaa tgaaagtcct tgtcgttggg cgtatttcat tatatgaagc
    19201 gggaggttct tatcaaatct atgtagagca catggagcct gatggaatag gtgctttata
    19261 tcaagaattg gaagaacgaa aagaaaagct gatgaaggaa ggcctttttc aagggcctaa
    19321 aaaaatgctg ccacgtttcc caaagcgaat cgcggtcctt accagtccaa gcggagcggt
    19381 tatccgcgat atcatcacga cggtgaaaag aagatatcca attgtccaat tggttttgtt
    19441 cccaacagtt gtacaaggaa accaagcagc ggacaatgtt gtcaggaata tccagagagt
    19501 agaagagatg ggcaatttcg atacaatgat catcggtcgt gggggtggtt cgattgagga
    19561 tttatggccg tttaatgaag agcgggttgc tcgggcgatt tatcaagcta atacgccggt
    19621 gatttcatct gtaggacatg aaacagatac cacgatcgct gatttagtag cagatgttcg
    19681 ggctgccact ccaacagcag ctgcagaatt agctgttcct gttttgtcag aagagttgat
    19741 gcgcattcaa gaacggcaag ctagattgca gcaggcgttt gtacgccaga tccagcgcaa
    19801 acaagaacgg ttcgagcgtg ctcgacgttc ctatgtattt cggcagcctg aaagattgta
    19861 tgaaggtcag accatcaaat tagaccagtt gaaacagcga ttatatcaag ctacacagca
    19921 aatttatcat gcgaaagaaa aacaaacgat cgcattaagc caccaattgg aacaagtggc
    19981 tccgctttat cgagttaaag cagctcgcca agaaactgct tatctagaaa aacgcttaga
    20041 agagaaaatc caacaatata tgaaacaaca gcagcagcgt tttgctcaag ctgttcaatc
    20101 tcttgatttg ttgagtccat tgaaaatcat gggaagaggc tacagctata cgacgttaaa
    20161 tgatcaagta gtaaaaagtg tcaccgagat tcatcaaggg gatttgctga cgatccatta
    20221 tcaagatgga atcgttaaag gacaagtaca agagatagac aaaggagaat aaaaatatgg
    20281 aaaatccaac ttttgaagag tcactgcaag aattagaaaa aattgtcatg cagttagaac
    20341 aaggagacgt tccattagaa tcagctctag attcgtttaa acgaggaatg gaattaagca
    20401 aacattgcca agatacatta gctaaagcag aagagacctt gacgaaaatg atgacagaat
    20461 caaatgaaga agttgatttt gacggaaacg aggaaagctg agatgagatt aactgacttt
    20521 tcagctattc atctacctgc tgtagaaaaa gaaatcttgt cttttttaga tgagcataca
    20581 acggatagag gactctatga tgcgatgagt tattcagtga aagcaggcgg gaaaagaata
    20641 cgtcccttat tacttttaac ggccgttgct tcctttgatg agcctattga tgttcccgtc
    20701 tatcaagtag cagctgcttt agaaatggtg catacgtatt ccttgatcca cgatgatttg
    20761 cctgcgatgg acaatgatga tcttcgtaga ggaaaaccta ccaatcataa agtattcggc
    20821 gaagcattag ctatattggc cggagatggt ttgcttacag gagcattcca gctaatcagt
    20881 atggcacact taggtaattc tcctaagctt ctgctgcttc agcaattagc tgtttgtgcg
    20941 ggatcacaag gtatggttgc tgggcaagct gcagatatcg agggcgaatc gaaaaagctt
    21001 tctttagaag aattagcatt tattcatgaa agaaagacag ggcatttgat tcgttatgcc
    21061 ttgctggctg gtggcatatt agcgaagcaa cctgaagaaa tcttattgct acttcaacga
    21121 ttagccgaac atttaggttt agcttttcag ataagagatg atctactcga tgtgattggt
    21181 acaacgaaaa cattagggaa aacagctggt aaagatgaac gtatggaaaa aaatacttac
    21241 ccgcgtttat taggcctaga aaagacacgt gaggcgttgg agattgagct gttatccgcc
    21301 aacaagatca tagacaaatt agaagaggac gttttttctt ttgatggcgg gctgatgcgc
    21361 cagatgatca agcaatttga tgtggagaaa tgagggaaag aatggaaaaa gaacgcgtag
    21421 atgtattagc ggtcaaacaa ggattatttg aaacaagaga acaagccaaa cgttcagtga
    21481 tggctggttt gatttacaac gaaaaaaacg agcggtttga taaaccggga gaaaaaattc
    21541 cagtgagtag tgaattaaga gtcaaaggta aaaaacttcc ttatgtttct cgagggggat
    21601 taaaattaga aaaagcactc aaagcatttg atctatctgt tgaaggaaaa acattgttag
    21661 atattggtgc atccactggc ggatttactg atgcagcttt gcaaaatggc gcaaaaatga
    21721 gttatgcttt agacgttggc tacaatcagc tagcttggaa aataagacaa gatcctagag
    21781 tcgtcgtaat ggaaagagtg aattttcgtt atgcaaaacc cgaagacttt accttaggaa
    21841 ttccagaagt tgctgttatc gatgtttctt ttatttcact aaaactgatg ctgcctccat
    21901 tacatgctat tttaaaagaa gagggagaag tgattgcttt aatcaaaccc caattcgaag
    21961 caggcagaga agctgtaggg aaaaacggaa ttgttcgtga ccctcagacc catcaaaaag
    22021 ttttagaaga cattttgtca tttgcggcac aaggtggata tgatgtgctg gaattaagtt
    22081 attctccgat cacgggggga gaaggaaata tcgagttctt ggctcacttg aggaaagtac
    22141 ccgaaagcgg aacaatcaat tcagctatta atatggcaga agtggtttca aatgcacacg
    22201 aacagtttga ccataaataa attgtaactg tgaaaatcaa gtgagaagta tgcggattct
    22261 tctttattat accaaggaaa taagctatca ttgattaaga agaatatgct aaggagcgaa
    22321 gacgtaatga gaaaaaaaga tcggcatcgt ttgattactc gattgttgag tgagcaagat
    22381 atccgaaagc aggaagaatt tgttgaaatc ctgaaaagca aaggaatatc tgttactcaa
    22441 gctacgattt ccagagatat aaaggaactg aaactgatca aggtaccggc ttcagatggc
    22501 ggctaccgtt atagcatacc agctgaaaca aacgaagatg taaatactaa attggaaaaa
    22561 ctattaaaag acgctttcgt ggcagttgac caaatggaaa aatttgttat tttgaaaaca
    22621 ttgccgggaa atgcttcggc agcagcaaat ttgattgata aacgttacaa gaaagaatta
    22681 ttttcgatta tcaatgatga cgataatgtt ttgatgatta cacgaactga agaccaggca
    22741 gttttattga agaaagactt cctgcattac ctttaagttg aggagcgaat gtgatgctac
    22801 aagaaatcag tattactaac tttgcgatta ttccggaatt gcggctttct tttcacgaag
    22861 gaatgaccgc gctgaccgga gagactggtg cgggtaaatc cattattatc gatgctttag
    22921 gtctgttagc aggaggaaga ggttcaagcg attatatacg tcaaggagca gaaaaatgtg
    22981 tgcttgaagg gttgtttgaa ctaccaaaac aagaaggatt ctctgaactg atggttgaat
    23041 tagggatcga aacagatgag gacaatctga ttgttcgacg ggatatgtcc ttaactggaa
    23101 aaaatgtttg tcgagtgaat ggtcatatta tcacattagc taatctgaga agaatcggca
    23161 gttatttagt agatatccaa ggacaaaacg aacatcagga actgctccag cctgaatcac
    23221 atcttgcttt attggatcgt tttggagatg tagctttcca acagaagaaa aagagttatc
    23281 agcaagaata tatctcttat cgtgagctgg aaaaaagggt acgaaaagtg cagcaaaatg
    23341 aaaaatccta tgttcagaga atagatatgc tccatttcca gcaagaagaa atagctgctg
    23401 ctgatttgca agtcggagaa gaagagaaat taaaagaaga aagagaaaaa cttagcaatt
    23461 atcaaaaaat tgctgatgga ttagctgcag gttacggagc actgacgaat aatgaacaaa
    23521 acagtgtaga tggtgttggc ttggccgttt cagaactgca agggatcgcc catctagatg
    23581 tggagtatga agcaatttat gaaaatatcc aaagtgctta ctatttgctg caagatgcaa
    23641 tcggcgatat gagtcgtcag attgatttat tggagttaga tgagagtcgt ttagaagaag
    23701 ttacgcaacg tttagaatta atccgacagt tgaaacgtaa atacggcgaa tccattgagt
    23761 caatattggc ttactatgac gaaatcaccg aagagctagc ttcttctgat ttttcagaag
    23821 gtcaattgga caaaatgaaa gaggaactag agcaaaaaga gcttctactt cagcaacaag
    23881 ccgcagatct tcatgaagcg cgtaaaaaaa tcgcaaaaga attggaaaaa tccattctgc
    23941 atgaattgaa aagtctgtat atggaaaaca ctgagtttga ggtacgtttc ttaaaagaag
    24001 aaaatagaca attgaatcat gatggatttg accaaatcga attttacatt acgaccaatc
    24061 caggagagcc actgaagcct ttggtgaaag tcgcttctgg tggcgaactg tctcggatgt
    24121 tgcttgcttt gaaaactatt ttttcttctg agcaaggtgt gacaagtatt atttttgatg
    24181 aagtggatac aggtgtgagc ggaagagttg cacaggccat cgcagataaa atttctcaaa
    24241 tatcgaaata ctctcaagtt ttgtgcatca ctcatctgcc tcaagttgct gcagtcgccg
    24301 actatcaata ttatattgtg aaagcagtga ttgatggacg tacgcaaact tctgtttcag
    24361 agttgaaaac aaaagaaaga gaagaagaaa ttgcacgtat gctggctgga agtgagatta
    24421 caaaactcac actcgaacat gcaaaagaac tattgaaact cgcaaaaagg acctgagcca
    24481 cctcgcagtg gttcaggtcc ttttcagcag ctgatagcta tatttt
//
LOCUS       DAXLPQ010000038        24272 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.038, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000038 DAXLPQ010000000
VERSION     DAXLPQ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.038"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..572
                     /locus_tag="ACF3UO_001836"
     CDS             <1..572
                     /locus_tag="ACF3UO_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFD3657835.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="ACF3UO_001837"
     CDS             576..1217
                     /locus_tag="ACF3UO_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657836.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDFIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="ACF3UO_001838"
     CDS             1214..2131
                     /locus_tag="ACF3UO_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3657837.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="ACF3UO_001839"
     CDS             2128..2799
                     /locus_tag="ACF3UO_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657838.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="ACF3UO_001840"
     CDS             complement(3340..3828)
                     /locus_tag="ACF3UO_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFD3657839.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="ACF3UO_001841"
     CDS             complement(4029..4295)
                     /locus_tag="ACF3UO_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3657840.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="ACF3UO_001842"
     CDS             complement(4295..4558)
                     /locus_tag="ACF3UO_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3657841.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5079..5219
                     /locus_tag="ACF3UO_001843"
                     /pseudo
     CDS             5079..5219
                     /locus_tag="ACF3UO_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5361..7184)
                     /locus_tag="ACF3UO_001844"
     CDS             complement(5361..7184)
                     /locus_tag="ACF3UO_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3657842.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="ACF3UO_001845"
     CDS             complement(7782..10487)
                     /locus_tag="ACF3UO_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFD3657843.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="ACF3UO_001846"
     CDS             complement(10793..11740)
                     /locus_tag="ACF3UO_001846"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFD3657844.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="ACF3UO_001847"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="ACF3UO_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3657845.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="ACF3UO_001848"
     CDS             complement(12375..12737)
                     /locus_tag="ACF3UO_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFD3657846.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACF3UO_001849"
     CDS             complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACF3UO_001849"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFD3657847.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACF3UO_001850"
     CDS             complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACF3UO_001850"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFD3657848.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="ACF3UO_001851"
     CDS             complement(14365..15876)
                     /locus_tag="ACF3UO_001851"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3657849.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACF3UO_001852"
     CDS             complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACF3UO_001852"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFD3657850.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="ACF3UO_001853"
     CDS             complement(17703..18779)
                     /locus_tag="ACF3UO_001853"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFD3657851.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="ACF3UO_001854"
     CDS             18975..20720
                     /locus_tag="ACF3UO_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFD3657852.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="ACF3UO_001855"
     CDS             complement(21000..21437)
                     /locus_tag="ACF3UO_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFD3657853.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="ACF3UO_001856"
     CDS             complement(21421..22794)
                     /locus_tag="ACF3UO_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657854.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="ACF3UO_001857"
     CDS             complement(23116..23604)
                     /locus_tag="ACF3UO_001857"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3657855.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="ACF3UO_001858"
     CDS             complement(23626..24228)
                     /locus_tag="ACF3UO_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3657856.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5166 c         4485 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgattttatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agcccaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgcc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctt caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa acttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc acggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc tt
//
LOCUS       DAXLPQ010000039        23739 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.039, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000039 DAXLPQ010000000
VERSION     DAXLPQ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.039"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(74..376)
                     /locus_tag="ACF3UO_001859"
     CDS             complement(74..376)
                     /locus_tag="ACF3UO_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFD3657857.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(402..833)
                     /gene="ruvX"
                     /locus_tag="ACF3UO_001860"
     CDS             complement(402..833)
                     /gene="ruvX"
                     /locus_tag="ACF3UO_001860"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFD3657858.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(830..1096)
                     /locus_tag="ACF3UO_001861"
     CDS             complement(830..1096)
                     /locus_tag="ACF3UO_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFD3657859.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(1350..2075)
                     /locus_tag="ACF3UO_001862"
     CDS             complement(1350..2075)
                     /locus_tag="ACF3UO_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFD3657860.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(2441..2511)
                     /locus_tag="ACF3UO_001863"
     tRNA            complement(2441..2511)
                     /locus_tag="ACF3UO_001863"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2477..2479),aa:Gly,seq:ccc)
     gene            2628..3380
                     /locus_tag="ACF3UO_001864"
     CDS             2628..3380
                     /locus_tag="ACF3UO_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFD3657861.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            3396..3875
                     /locus_tag="ACF3UO_001865"
     CDS             3396..3875
                     /locus_tag="ACF3UO_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFD3657862.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(4126..5706)
                     /locus_tag="ACF3UO_001866"
     CDS             complement(4126..5706)
                     /locus_tag="ACF3UO_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFD3657863.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(5699..6442)
                     /locus_tag="ACF3UO_001867"
     CDS             complement(5699..6442)
                     /locus_tag="ACF3UO_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3657864.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(6618..7394)
                     /locus_tag="ACF3UO_001868"
     CDS             complement(6618..7394)
                     /locus_tag="ACF3UO_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFD3657865.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(7642..8478)
                     /locus_tag="ACF3UO_001869"
     CDS             complement(7642..8478)
                     /locus_tag="ACF3UO_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFD3657866.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(8489..9418)
                     /locus_tag="ACF3UO_001870"
     CDS             complement(8489..9418)
                     /locus_tag="ACF3UO_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFD3657867.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            9610..9963
                     /locus_tag="ACF3UO_001871"
     CDS             9610..9963
                     /locus_tag="ACF3UO_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFD3657868.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(10037..10693)
                     /locus_tag="ACF3UO_001872"
     CDS             complement(10037..10693)
                     /locus_tag="ACF3UO_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFD3657869.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            10919..12853
                     /locus_tag="ACF3UO_001873"
     CDS             10919..12853
                     /locus_tag="ACF3UO_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3657870.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(12939..14162)
                     /locus_tag="ACF3UO_001874"
     CDS             complement(12939..14162)
                     /locus_tag="ACF3UO_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3657871.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(14156..16027)
                     /locus_tag="ACF3UO_001875"
     CDS             complement(14156..16027)
                     /locus_tag="ACF3UO_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFD3657872.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(16048..17166)
                     /locus_tag="ACF3UO_001876"
     CDS             complement(16048..17166)
                     /locus_tag="ACF3UO_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3657873.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(17249..18082)
                     /locus_tag="ACF3UO_001877"
     CDS             complement(17249..18082)
                     /locus_tag="ACF3UO_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657874.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(18075..18992)
                     /locus_tag="ACF3UO_001878"
     CDS             complement(18075..18992)
                     /locus_tag="ACF3UO_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657875.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(19219..20343)
                     /locus_tag="ACF3UO_001879"
     CDS             complement(19219..20343)
                     /locus_tag="ACF3UO_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3657876.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            20526..21434
                     /locus_tag="ACF3UO_001880"
     CDS             20526..21434
                     /locus_tag="ACF3UO_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3657877.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            21575..23188
                     /locus_tag="ACF3UO_001881"
     CDS             21575..23188
                     /locus_tag="ACF3UO_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3657878.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
BASE COUNT         7392 a         4657 c         3966 g         7724 t
ORIGIN      
        1 gtgctaaacg aaaaaaccgg gctctacttt tcagagagtc cagcttttct tacaccttat
       61 cgattctttt gttctattct tcttccgcca tgaatgtatt gaatacttct tcgatcatat
      121 cccattctgc gtctgtttcg atttgttcta actcgccttc tgttccatct tcgttttcga
      181 tgtatgcata agcttgtaat tctacatctt catcttctga aacaccagct ggatataaaa
      241 gaacatagtt acgtccaaat tcttcttgtc cgtcaactgt tagcaagatt tcgtataatg
      301 tttcatttcc ttggtcatcc accaatgtga tgtgttcgtg tccttcgtgt tcgtgggaat
      361 ggttatgttc tgtcataaga ttacctcttt tctttttatt attaaaataa ttgcttacct
      421 gagccgtcta aataattttg taaaatcatc acagctgcta atttatcgat gacttttttt
      481 cgtttcgctc ttgaagtatt tgcctgctct actagcatac gttctgcctg aacagtggtt
      541 agtcgttcat cttgataatc aaccggcaag gagaatagtt ctttgatctt ctctccatat
      601 gacatggaag cttctgccct tggtccgatg gaattgttca tattcttagg taatccaact
      661 acaaaacggt ctacttcgta ctgcgccact aattccttca accgatcaaa accaaactct
      721 tcttctgcct cattgattcg aatgatttct actccttgag ctgtccagcc aaagggatcg
      781 ctcacagcaa cgcctactgt cttagaaccg acatccaagc ccattactct cataaattca
      841 ctccatgatt tgagaggtag tctttgacaa ttacttccat gatttcatcg cgttcgtgac
      901 ggcgaatcaa atttcgtgca tcacgataac gaggaatgta ggccgggtct ccagaaagca
      961 agtagccgac aatctgattg attggattgt agcctttttc ttccaaagcc cgataaacaa
     1021 tcgctaatgt ttcgctcact tcttttttgc gactatcgtc aaaaccaaaa cgtacggttt
     1081 catctgtaaa acccatgatt ctacacctct ttcccgcaag gtaattccag cttaccttct
     1141 acacccttat tttactcgaa gaaagggaaa actacaaaca aatattccaa acttctgaat
     1201 aaattaagaa acacgatttg tctgattttt ccttttttct gtggcttttt caaaagccct
     1261 ctttccataa agtatacgct atatttcttt gaaagtatgt ttttacacaa ttttttcata
     1321 aagttcataa aaaattcgaa ttgctgctac taatttttcg ttttcgttgc ttgccctgtc
     1381 tcataattga tggtgtagcc atcttgaaca ttgtagataa agacattgaa ttcaattttt
     1441 ttgtcttcaa tgctttctgc ttccaactgc acacctcttg ctaccagttc atttccctcg
     1501 aaatgaggag tgacacgata gcgtacatga tgatttgttt ccttgatata tgccgcaata
     1561 tcattttcgt gggcaagcat gtacggagca ttcaacgaac gtgtccctgt cattaagttt
     1621 ttaatgttat tattttgacc agtcaactgg aaaccaatca aatggctgcg gttgtataac
     1681 cattgtccgt cacttaattt cttttgtttc caacctgtcg gatcaatata caaaggttct
     1741 ctcttttcag taggaaacaa gtcttttccc aacatcgcat tggcttgtcc tactctgttc
     1801 aatttgtcta tatttgaata gctttcccat gtccctttgg aaagactaag atcctctttt
     1861 gtaaactccg gctgattccc attgatttct atttcttgat gttttccatc atattctggc
     1921 acatccgcta cttgagaagc ttgcggtgtg gaatcaaaaa tggttgtaat ttgttggaag
     1981 atatctgaat ctttttgtgt ggtggaaata ccgagtgccc ctgcaatcac agcagcgacg
     2041 atccccacga tcgccttggt tgtttttttg ctcatttctt tactccttta ctaacagttc
     2101 cctaaatctt aacatatgtt cccctataaa taaatactgg aaagaaatag aaacagtaaa
     2161 aaaataaaac cagtttttag acggcttaag aatacaaaaa aagagacgga ttcatcgtct
     2221 ctactcaatc acaaaacact atttacaagg tatttattat cattcaaaaa atttttctta
     2281 atactcaaaa ctaaacggct tctgtacgac ctcttggtaa acagtgttca aaagcttgca
     2341 tctgcggtaa taagtccaac caagtcaaaa acataagaag cttttttgct tgactattct
     2401 tattacttga tgcagggcag ctttttcaca gcctctttta agcgggtgac gggaatcgaa
     2461 cccgcgacat cagcttggga agctgggatt ttaccactaa actacacccg cgatacaaaa
     2521 acagtatacg cctctttcac tccttcctca agttttttta ttctttacgc ttccgatatg
     2581 ttttgtagta aaataaaact aatcaatcaa ttattggaga agatgctatg acgggaaaag
     2641 aattagatct gttgctggac acttgtttac tcgctgggaa aatcatgatg gaaagcaatg
     2701 cggagatgta tcgggtagaa gatacgatga gtcgaattgc tttagcttct ggaaatttcc
     2761 gtttggtcag ctatgtcact caaaccggtc tctttattgg tcttgatcgt acctcgacca
     2821 tccgaatgga acaaattacc aaccgttcga ttaatttaga aaaagtagta aaagtaaatg
     2881 atctttcacg taaatatgtt gcttcagagc taacattaga agaactttac tgcgaactgc
     2941 aagcaatcga ccgagaccgt tctttctttc ctgtctggtt gcaaatcgtt agcgcggcag
     3001 tgatcagtgg aacaattatg gtgttatttg gcggaaagat gaccgattta cctgtgactt
     3061 tagtcattgg aggattggga tacgcagctt atctatatag tttgaaattt tttagaatca
     3121 aatttttatc ggaattttta tcttctttat tgattggcat agccgctatc tacagcgtac
     3181 gttttggctt aggaagcaat caggatctaa tcattatcgg atgtgtgatg cctttagttc
     3241 ctggagttca aattacgaac gctatccgtg atttgctagc tggacattat gtctcaggag
     3301 tttctcgcgg aacagaagcg atgatgactg ctacgatgat cggttttgcg attgctttta
     3361 ttttccagct tttttattag gaaaggaaca caagtatggg gacgatattt attcagtttt
     3421 cttttagttt tttagcgact gcggcatttg ccgttattac aaatgtacct aggcgttcat
     3481 tgatttgttg tggtctttct ggtgcttttg gctggatgat ctactggatc tgtgttcaaa
     3541 taggcggatc tgctgctttt ggttcattgc ttggttcttt aggagtagca ttcatcagcg
     3601 atcttttctc taaacgtttg aaaatgcccg taacgatttt caatattccc gggatggttc
     3661 ctctagtccc tggtggttta gcttatcaag cggttcgaaa tctcgttact gaatcctatc
     3721 gagaagcggc tcattatgcg gtccaagcaa ttatgattgc tggagcaatc gctttaggtc
     3781 ttgtattatc agaagtcttt aaccataaca tccgtaattt caaagtaaag cgtgacgcaa
     3841 tcatgatgaa acgaaaaaaa cggcttttta aataaacgaa gtgtaacaaa gaaaaggttg
     3901 tgaaagagac gttcagcctt gagcgatgac aaaatatctc acaaacattg cgacaagtaa
     3961 ccgcaggagc aataagaagt aattatgagt attaaaaaaa gttttgtaaa aatagcttct
     4021 cacattttta cataaaattg acttaatact gagaaactga cttttgaaca ccctctatct
     4081 gtaaaaaagg ggctgcgaca tgatttttgt cacggcccct cttctttatt caaatttttt
     4141 ccaaaacgtt cgttgataat aaacgatcca tagagcggaa agtattagaa ctaaaccgat
     4201 cacaggaata ttcactaacc aaaatggata aaacaaagcc aacattccgt ataagacgat
     4261 aagaataata ctgatgatca atgaacccat catagttgcg actaaaccca aacttcctga
     4321 acctctgtta aataattggt taatattggt ccagttcagc agcagcaacc gataatctct
     4381 agcgaaataa cgtagtgaca ataagtagca gccgaataaa gaaccaaata gcaagctagg
     4441 gataaaaaac aaaggcagct gaaaagacag tccgcttaat aatgcgatcc caccagttaa
     4501 aaaactctgc aatatccatc cgaatctgaa cttttctttt aaatattggt tcatagagat
     4561 tggcaaagaa cggataaaca gaaaattttc ttgatccaaa gaaataagat tgctgataaa
     4621 agaagtctga ttaactgtta agaaagccaa tgcgatccct accaggaaaa caacaccgat
     4681 taacttatta tctaaatcag ttaattttat ttcgcctcct agggcaaaag caagaataaa
     4741 aatgattgga gttaacaagg aagaagaaag aacttgcata atcaaattag gttcttttac
     4801 taattgagca ttgtaactaa ataaaagctg atgcacattt tggttctttt tatgggttct
     4861 ttttattttg aactcactgt ttgaatcagt cagttgctct gtaagctttg gtactatcag
     4921 ctgttttaca gcaaggaaaa atcccagagc cgtgatagct agtattcccc aacccaataa
     4981 accttgttga gaaagtggct gactggcagc atcatagaat ggcaataata tcgaaatcgg
     5041 atgccgatct gttaactcat tttcaatagt ccccgtttga tgattcatcc acatgattcc
     5101 agcaaatgcg atcagcatcg agctgccaag caagatacta gaaactgttt ttctatgttt
     5161 tttaaacact gctgttcgag ccaaaccaaa aacaatcaaa ctagccagac aaaaaagaat
     5221 aatcaaaaat agagaaaaca aaaggattga gataatgata gtaagcaaaa tccctagatc
     5281 agctcgccat ccggttaaaa taaacatgac tagaagcgga aaaacaaaag gaatgatggt
     5341 caaagcaact accaaaatct ttgctgaaaa aacctgttct tgtccaaaag gcagaggcaa
     5401 aaatacttgc aggtcatttc cttcaaaaaa gatattataa atgactgata tactttgagt
     5461 taaacctaac ataccaaaaa gtgccacgta ataagtaaag aaacctggca atttaacaaa
     5521 gttcatagca aacatagcaa atccgtaaat cagtaaaaaa atcagccctg aaaaaagatt
     5581 ttgagacaaa agatagatag ttaatcgctt tccctttttt cctttctctc ttgctttatt
     5641 cgtgagctgt ggattaacat ataaaagatt aactcgaatt aattctaata attgtcgctt
     5701 atacatacgg tccatctcct gtcgcttgcc ttccagccat tttcaaataa atcttttcta
     5761 gcgtttcatc aggtgagcca ttcaataatt cactaactgc cccctgataa atcaattcac
     5821 ctttcttcaa aatagccagt ttatcgcata actgttgtgc ggtatccaat acatgtgtag
     5881 aaaaaatgac tgtttttcct tttgcggcat gagccttcat catttctttc aaatcaaatg
     5941 ctgcttgagg atcaagtcct tgcaaaggtt catccaatac ccaaatatct ggatctggca
     6001 gcaacgtgcc gatcaaaatc gttttttgac gcattccatg tgaaaaactt gcgattgttt
     6061 cattttgatg actatacata tcaaaaagcg ctgtcaattc tgctaaacgc ttttcttttt
     6121 tttgtgtgtc taattcatag gcagctgaaa tcaagtccca atattctcca gccgtcaatt
     6181 gtaaaaaaat atctggggaa tcaggcacat aaccgatttt ttgtttgata ctcaatcgat
     6241 tttccgtcaa tttcattcca tctactaaaa tcgttcccga tgatggttca ataatactaa
     6301 ctaaactttt aatcgtagtt gattttccgg caccattatg tcctaaaaat ccaaaaattt
     6361 ccccttgtct tatcgagaga gacaagtctt ttaatgcttg ttttttcccg taacttttac
     6421 ttacattgat gaattcaatc atttctgtac tccttttgtt tgttattact ttttattgta
     6481 cccttcgtta ttggtggagt aaatgtcaaa aagagtgcat aacaaaaaag gatagaaacg
     6541 actaggctgc tacttgggtt gttctcttct acaggaaaac actcttctaa caggtaagat
     6601 atgagtcttt gttttcttta aaatgattca ttttctatct tttcttgcat aaaattcttt
     6661 agtttatcaa tacttctctt tcccatctct agttgttctc catttgcaaa tgttactatt
     6721 tcgtttactc tgctaataga tgtaatgttt tcagtattaa tgatataagc ttttaaatct
     6781 ttacataaat actcatattc gagtgatttt ttatattttt taattgtgcc gtttacgaga
     6841 atctcttcat ctttcaatac taggcctatt ttatttttat aacctggcat gctcattaga
     6901 taaaggattt catcgtaatg gatatagtga tcgctattac cataacggac agttgtccac
     6961 ctttttttcg tagcatgttg aacaggatag ttttcttttt ctttcaataa gtaactttgg
     7021 atgctttttt tatttttttc ataagtgaat tcttttatca aataaccact aggcgtaatc
     7081 tttcgattaa taacagttat tgctttattc ggatgagacg ttagataaac aattttacac
     7141 ttttcattct tttctctaag catttcgcct agttcgatac cgctataata ggcgttcaaa
     7201 tcgatgtcta ggaaaaaaat atctgaggaa tagatttcat tatttttaat gaattcaaca
     7261 aattgtataa cgttcaatcc ctgaacgatc tcaaatttcc aaggacttaa taaaattctg
     7321 gattcttcca aaatttctac tagcattttt tcaaaaacca aactatcatc caaaataaat
     7381 atacgcgtta ccataaaaag tacctccact cgatatttta ctatcaaaat catttcatac
     7441 aacttttcaa catacatgtt aggaataaat tgtaattctc ttcacaatct tttccaacac
     7501 ctttgaaacc gatatcaaat actttcagga tgctgcttct aaaataaata tcaaacaaat
     7561 gaatacatca tgcaaaaaaa gccagacaac cgacgtcctt gcgtgtcagc tgtctgagct
     7621 atgtttattt attttgttct tttaaaaaga acgatacaca tactgatttt tcggagcaga
     7681 gactttctca gcgtttgtaa caactacaga tgggatttca cgcttgaatg gttgataata
     7741 gtctgattgg atggttcctt ctattttata ccattcatca tttttaaccg ttactccttc
     7801 cggcatatgc gtcaacaaac caaagactcc tgaatctgcc acacaatgga taatgccgaa
     7861 tcggaacaag aagatatctg tattgctatc gttcggtgtt tggtaaacaa atccttcata
     7921 gctgattttt ttgccaatga attcgctagg gtaattataa attagctcca taacttctaa
     7981 atagttttca tctgtgatct tgatagtttg cttatcccca tacttttctt tcaactcatt
     8041 catttggtct aagtagtctg atttgttgaa ataaatactg gtatccggct ttaagtattg
     8101 tgtctgcatc tccggatccc ctactgattc tttacttact gggaaattaa atcctttggc
     8161 ttctacgatc gtagtgtcga gactaactgt tggaaacaac gtccccacga ttactggcaa
     8221 agctagcagt acataagcga ttccacgttg ataaggtttt gacaacccat ggtcatgatc
     8281 gtgctcgtgt gccttttctt ctgcttttcc gtttttgacc cacaaataca gctgaactaa
     8341 agccaaaaga gcagataaaa tcattgaaag aatagctaag tagcgataat ggacattgat
     8401 atattgatcg agtttgccag aaacttgcaa gtacatcatc aattcgaaat acccagataa
     8461 aatcaaaaac cgcagcatat tttccctcct aaataaataa tgtgaatcca ataacgctaa
     8521 gggcaatcag tccgatcagc gataaaataa agcgtcctgt aaaatatcgt ttcatcatca
     8581 gtagattttt gatatcgacc attgggccaa agaccaaaaa ggcagctaca ggtgctgtgc
     8641 cgaacagact taacaaagaa gatcctataa acgcatctgc ttctgagcaa agagacatcg
     8701 taaaggccaa taacagcatg atgataatgg ctaaaatctt tgttgagccg agcgttagca
     8761 taattctagt tggtaaataa gtctgcatcg cagctgcgat taatccgcca atgatcaaat
     8821 aacgacctgt atcaaaaaat tcgtcgattg aatgtgtcaa cacatgccca gtttgatgga
     8881 tcagctgatt ttttggttca ttcttctcac tttgttcttc ttcatggaca tgatgatggt
     8941 gattttctgc tactttagac gtgatttttt ctttcaatac agcgtctttt tgaaaatagg
     9001 caagccagac accaatcaca agggcaacaa aaaagctgcc tatcacccgc cagcttgcca
     9061 tctgccaaga attgccaaat gcgataaaag tggaaaaaat cacgattgga ttgatgatcg
     9121 gagcagtcag cataaaagca aacgctgtgt gaactggtac gcctttttta acaaattgat
     9181 gaacgatcgg tacgatgccg cattcacatg aaggaaagaa aaatcctaag atcgaaccag
     9241 taaaaataga gaagatacga ttttcaggaa gccatctctt cacacgttct ggggtcaaaa
     9301 atacttgtaa ggcgcctgag ataagacagc ctaataatac gaaaggtaat gcttcaataa
     9361 cgatcgataa gaaaatcgta ctcatctgca aaaccgaatt tggaataaaa gaaaacatga
     9421 gtttcctcct ttttatttct agttcattcg ctttgcaaat atacgctttt attcaaaaaa
     9481 aacaagttgc tctgtaaatt tttacacaac tcttattttt taccaaagca cttcaattga
     9541 ctttttctgt tattcccatt aaattaaggt ctcatacata tcacttctat cataaaaggg
     9601 agaataaaaa tgaaacaaac cactaacttg actgaagttc aagacatact gcaacagtca
     9661 tccgttgccg tcatttatct ttcgatgcct aattgcagtg tttgtcacgc tgttcgtcca
     9721 cgactagagg aacttctcac acattatgat attccggcac ttcatttgga tgcatttgaa
     9781 acaccagaag tagctagtaa atttgaagtg ctgactgcgc cagttgtcct gatttttcat
     9841 caaggaaaag aagtctttcg gcaagcacgg ttcatcgact ttaaaaaaat ccgttatcta
     9901 ctagatgaac tgacagcaga agatgattcc ctttcttatg aagaaatctt ccgaacaaaa
     9961 taatcgttgt ccaaacagaa aaaagcgatt gaacaagtga aagttttgcc ttcatttgtt
    10021 caatcgcttt ttatttttat tctgctgtat tttcggaatg cgcatttgcg tcagaatgca
    10081 agaaatagat caaggtttgc aattcattcg tcaaatcaac attttggatc aatacatctg
    10141 acggagcatt caatcgagca gcggtaaagt tcaagattcc tttgattcct gcttccgtta
    10201 actgattgac tacttcttgt gctctttcag cgggtatcgt taaaattgct acttcgattt
    10261 gttggatctt gatttgttct gacatatctt ccattggata aacggggata ccgtctacga
    10321 tgcgcccaac gatttcctca ttcacatcaa aagcacaact gatacgtatg ctattacttt
    10381 gatggaattt gtattttagt aaagcacttc ccaagttccc tacaccgatc agcgcaacat
    10441 ttgtcaattg atcgtcgttt aatgtctttg caaaaaagtg cataagatct tctacatcat
    10501 aaccataccc acgttttcct aattcgccaa aataagaaaa atctcgacgg atcgttgcac
    10561 tatctacttg aacggcttca cttaattcag ttgaagacac ttttttcttt ccagcattat
    10621 ttaaaatcct taaatagcga taatacaaag gcagtctttt agctgtcgcc tttggaataa
    10681 tatgatcttt cacgaaatga cctccacgta ttgtctaatt acatctttga tttctccatc
    10741 atagcagtat ttataggaaa aaatcaattc cattgctcag atattgtgaa attttattct
    10801 ttattcattt atttatcatt tctgcaaatc tcgcagtata atggaattta tggtagacta
    10861 ctaattgaaa aatagttttt tatttgagga gaattcacaa agtagaaaag aggattccat
    10921 gatattatta caagccaatc agattgctcg ccattttggt gcagaagtct tatttgaaaa
    10981 catacattta gaaatcagta caggcgctcg tgtcgcttta gttggcagaa atggcgctgg
    11041 aaaatcgact ttattaaaga tcattgctgg aattgaagca cctgatgaag gaaagatcgc
    11101 taaaaataaa acagcgactc tcggatacct cgctcaggac acaggacttg attccaatga
    11161 aacagtttgg aacgagatgc tgaaagcttt tgaacaagtt agacaaatgg aagagcggat
    11221 gcgcgagcta gagattttca ttagcgaagg tacgccagac acacctgctt atagttctta
    11281 tttaaaagaa tacgaccggc tgcaacacga tttttcagat cgaaacggct atggttatga
    11341 aaatgaaatt cgttccgtat tgcatgggtt taaattcgat tcttcatttt atgatcagaa
    11401 aatcgatact ttatcaggcg gacagcgcac acgtttagct ttagctcgca tgcttttgca
    11461 acaccctgac attttgattc tagacgaacc aacgaaccat ttagatatcg agacactttc
    11521 ctggcttgag aattatctgc aaagctatac tggtgcatta ttgattgttt cccatgaccg
    11581 ttatttttta gataaagtag tcaatgaagt ctatgaatta agcagaagaa aaatgcgcca
    11641 ttacaaaggt aactattcga aatatctaga tttgaaagca gaacagttag caagtgaatg
    11701 gaaggcttat gaaaagcagc aaacagaaat ccataaatta gaagacttcg ttgctcggaa
    11761 ccttgttcgc gcctctacca caaaacgagc gcaaagccgc agaaagacat tagaaaaaat
    11821 ggaccggctg gatcgtcctc aaggggatga aaaacaagca aactttctat tcagtataga
    11881 aaagccttct ggaaatgtag tcttgcaaat cgaagatgcc gctatcggat atgataatgt
    11941 caccttatct gaaccaatca atctagatat ccgtcgtcaa gaagcgattg ctctagtagg
    12001 tccgaatggt atcgggaaat cgacgttgct gaaatcaatc attcaccaga tcccttttat
    12061 ccgtggaaaa gaaacgctag ggacaaatgt caccatcggc tattacgatc aaggtcaagc
    12121 tgatctgcat acaaacaaga cgatcctagc agaattgtgg gatgagcatc ctaccactcc
    12181 agaaaaagag atccgaagtg ctttaggtgc tttcttattt tctggcgaag atgtagaaaa
    12241 accaatccct ctgctaagtg gcggtgaaaa agcacgggtt gctttagcca agttagcgat
    12301 gaacaaagaa aattttttga ttttggatga accaacaaac catttagata ttgacaacaa
    12361 agaagtatta gaaaatgcat tgatcgatta tgacggcaca ctgctttttg tttcccatga
    12421 ccgatatttc atcaatcgga tcgcgacaaa agtcgtcgaa ctctctgaaa atggcagcaa
    12481 agtctatcta ggagactatg attattattt agagaaaaag caggaagaag aagaaatcgc
    12541 cgaattgttg gcacaagatg agccagaatc tgctcctgct cccacgaaca aatctgatta
    12601 ttaccaaagc aaagaacagc aaaagcttat ccgtagcctt caacgaaaaa ttactcaggt
    12661 tgaagaagaa atggcgcgga tcgatgaatg gatcgatcag ttggaacaag aaatggtcgc
    12721 gccagaaaac ctggaagatc acgtaaaact caatgagctg aaccaagatt tagaagctgc
    12781 tagacaagat caagaaacaa aattgacgga atgggaagaa ctaagcttgg aattagaaga
    12841 atatgaaaat taacgaaaaa accaaaacag aaaccattca tgctgttttg gtttttcttt
    12901 ttttatttta tcaaacaaaa attccatatt tacctttttc accaataaga agaccaatta
    12961 ctagtcattc tcactaaagc ttctaaataa tagtaatcac cccaaataca aggtgtattt
    13021 accccattat ttttgggctt attataaaca gactgtgtta aaaagccatc ttcttcttcc
    13081 gttgtagcat atctttcttt caattgtcgc ataattttcc aaacagcaga ctggtataag
    13141 ttcttttctg ttttgtctaa tagacctgat tctattaatt ctaataatcc acaaaccatg
    13201 atcaccatac tagatgtatc tttttcttct ctgctagaat catcaaagat caaatcccaa
    13261 taacaaatgg tatcttctgg caaccgattc ataaaataat tggctaatat tttgcttaaa
    13321 tcaaaatatt tttgttcttt caaataacga taacttaatg caaaaccgta aatcccccat
    13381 gcttggcctc tagcccaaca ggaattatca ctataacctt gatgcgtact tccatatctt
    13441 ggttttccat ctttgacatc catataaaat gtatgataag ttgaaccatc ttctcttact
    13501 aaataatctg ctgcattttg aatatgagcc tgagcagctt ttttatattt ttgatttcca
    13561 gtttcttcac tcgcccaata caataatgga agattcatgc aacaatccat gatcattcta
    13621 ccttgttgtg aaggatcact aggatctccc caagcttgta taactcctgc cttctcccaa
    13681 aaacgctgaa gtaatgtttc tgcagcatca attgaagctt ccttcatttt tcgatttccc
    13741 gttattttat aatctgctac ggttgataaa gaatacaaaa aaccaagatc gtgatgatta
    13801 gtgataattt gacagtcaat cctgtggata aaatctatat ctgctttttc agctgtttgt
    13861 tgaaataaag gatcacccgt cttctcaaat aacaaccaat taattcctgt ccaaaatcct
    13921 tctgtccaac caatattgtc tcttaatgga taacgtcctt ttataggaca ctcgcttggg
    13981 aattgatact gactgttact gatacgtttg attaacctct ccgtgtgtct gcgacaacgc
    14041 tcgatctcat tattccattc tttttccatt aattctttat aacattcatt tatccatttt
    14101 tctggatgta ttatctcttc aaacatcact ttatcaagca tttccccacc agcctttagc
    14161 ataattttag tcttttttta ttgtttttat tttggatagt tagcccggtt gtcccatcaa
    14221 aatcaatttt gggacgattg ttccatactt ctaaactata atcccgatct tgatgagcaa
    14281 ccactcctgt tccgagccaa tgggttcctt ttccaaatgt accctctaat ccaggaataa
    14341 aagtgttttc ccatgtcatc aagtttgtat tgggcaaacc cataatagct gtggattttc
    14401 gtttaatagt atcgtcactt aaacagataa tacctgaaaa gccagcttca ctcaccctat
    14461 agttttcctt gtcttcttct atgattattc cttctttctc aggagaacat tcaatagcaa
    14521 accctgtctc atatagaaca tattctgtat ctaattctac tttgtgtacg cgaatctgcc
    14581 agccttcaaa aggaataagc caagttctga tttttgcctg taaagtaggt tcccatgtag
    14641 aggcaagtac ctctttctta catacaatgt ctcgtacatt atttcgaacg atgaactgtc
    14701 cataggtttt gatgctctca ttcttaaaac tggtcgtgat atatgtgtcc gctcgctgaa
    14761 tccctagcat tgaatccatt gccatttctg ctttcaattg attcgctcgc ggtatcgaaa
    14821 aaccaaattg actagaataa gcaaatttta aatatttttc attggtcaat gtatggaaat
    14881 ttggccctaa ttgtcccgca ttcaaaaaaa atgtatgtcc attatcatgt tgtatgagca
    14941 aattggcttc tgaaagaagt ttagttcctt cacgaatagg cataggcatt tctttagccg
    15001 tccaatactc atggtcttca ggtagcgcca acaataaaaa aatcttattc agccataatg
    15061 gagataacgt actattatag ggttcagtca atgtcaattg agggtaggta taaccaatat
    15121 tcaggatacc tttttcatca aatatttctt tttgcatcca ccatcttata ttccgattga
    15181 ctaacccctt gatttcacct aatttaaaag gcaaaagatc ggcccacaac atagctgacc
    15241 aaaagcttga aactgcaaaa cgataaatca tgcttcgacc aaaaggcaca tttgcaccat
    15301 cttccgcaaa aaaatgaata tagtctctag aaaaatcaat agctcggttc ttatatatct
    15361 ggctaatggg cttttctggt tctagtacgc tataaatcaa accataataa tgaaatgcaa
    15421 aaggattata ataatcttgg cgacctcttg aactgtctcg ataccagcca ttttgaagat
    15481 aacaattttc tatattatca aatgcttctt tcagtgctga ttctttaact ggataaccaa
    15541 atttttggat aattgttccg acaattatct taaaaaattg ccaattacca tctgcacatt
    15601 catattcaaa aatttgcgag aaccaatgaa taatctggct tttttctcct gtatctaatt
    15661 ttttccataa taattgttca tgatgatata acgctaataa cattgcgggc atttctacca
    15721 tacgctggtc tctttcatgt atttctcccc aataatcggg atgggaagga tctgttccag
    15781 cttttattcc tgatagaatt aatttcaacc atcgttcatc taattggtca attgcgggcc
    15841 ccgctcccca taaaacccga gagaatcctt ccattcctgc aattttattt ccatatccta
    15901 ccccttgatg tatataatca atttgtgcgc cacttgctcg ataaaacggc tggagtggtt
    15961 gatttatctt tttaaataag tcaaagtaat cctgtctggt ccttaatagt ggtactggat
    16021 gtttcattgt attttctcct ctttttacta ccaaatagct aattccgact gttctaatcg
    16081 aagtaagcct tcaataaaaa aataatcaga atagatcagt ggcacattat aagtcagttc
    16141 tctatggtat gcttctgctc cgcctccaat gatcccatct tcatccatat tccaatttgc
    16201 atagtgcttt tctgtctttt ggagtatatt gatagcagct tcatgataca tttttgatcg
    16261 tacagaggaa acatatcctg ctaattccag aagaccgcat gcagcgcata ctccagcact
    16321 ggtatcaata ttcgaatctt ttacagcaaa atcaatgaga ggaatataac cagttttttc
    16381 gattttctga ataaaattta ctgctatctt ttctgctata gctagatagt acggattttt
    16441 tgtgtaacga taacttaacg cgaatccata taaagcccat gcatttcctc tgctccaaca
    16501 agaattctca ttgtatcctt gcccgccaag taaccgaata tatttccctg attctgcatc
    16561 aaattctgcg atatgcccgg ttgatccatc tttcctcact agatacttag ctgttgtatc
    16621 tgcatgctgc cgagcaattt tagagaacct cggatcacca gtttccctcg aagcccaata
    16681 cagtaatggt aaattcatca tactatcaat aatcatccaa ccaggtttat ggtcattcca
    16741 tgctactaaa tagttccctg aaatattata gcgtccagca agtaccgtag ctgcatgtaa
    16801 ccctagttgt cgactatgtt tgttttgaga ctgttgataa tgtgcaatag ccgatggtaa
    16861 gaataaaaaa cctacatcat gatgaacgtc tgaaaaatgg tacagggcag attctaataa
    16921 ttgttcttgt tgtattgctg cctctttgaa cttttctcgt tttgtcttgt gaaagagctg
    16981 ccataaaata ccactccaaa aaccattggt ccaccagtcg attcctctgt cctttattac
    17041 gtctgtatat tttccgttgt aagaaatata tggaatttta ttccccattc tgtctaattc
    17101 cgcatctatc ttttcagaag ctacattcaa aatttttctt gaccattcct tcgtctgttc
    17161 attcatggat atcccgccat tcttttaatt tttatgaatg tggagttgct cctagaacga
    17221 actagatggt taacattcgt tatttttttt acttatttgc agctccaatg tcattctcct
    17281 taaatttaga ctgcgcccac acataaatca agaccattgg gatcactgaa gttgctaaaa
    17341 ttagcataat tgcgccataa ttaattggct cacctgtact agaaaccgtc atatttttga
    17401 taattaaggg aaccgtatat ttatctttat ctgaaagcat gactaatgga aatagatatt
    17461 gattccaact tcccataaag ataagtaaac cactagtaat aatcgtaggt gataaaatcg
    17521 gtacagcgat tttcgtaaaa atcacccact cattggcacc atcgattctg gcagcctcca
    17581 tcagtgctgt aggaaattga ctgctatatt gtcgcatcat aaacactgaa gttgtactgg
    17641 caatcgaagg gatgatcaca cctgcataag tattcgataa tcctaaacga ctcataatgt
    17701 aaaataaagg aatcaatgtg gtaaaaaaag gcaccatcct agatagcata actgtattga
    17761 acaacagttt attccccata aaacgatact ttgctaatgc ataacccgcc attgtagaac
    17821 tggctgtagc tgaaactgta ctgattacag caataacaat cgaattccaa ataatcaagg
    17881 gataattata tctcgccatg atggcttgcc agttttttaa tagcatatcc ccaaacttga
    17941 aattgattcc gccacttaaa atttcttgat tactttgcgt tgaagctaca atcatatata
    18001 aatatggcat caaaaatatt aaggcaccaa acacaataat gacgtacgta aaaattctgc
    18061 tttgtatctt ttgtttagtc atttttatca cctccgaatt taaattgaat agccgataat
    18121 ataacagata caaacaccat cgtccaggca atagcagagg cttttccaaa atcaaccatt
    18181 tcaaaacttg ttttatataa attgactcct acgaccaaag ctgaattttc tggtccattg
    18241 gaagtcccaa agaatatatt tgggatattg aaattaccca agccattgat agtggctaaa
    18301 actgtggcca ttaaaatgat tggctttagc atggggatcg ttaataaaaa gaattgccga
    18361 aatttcgatg ctccatctat ttcagcactt tcgtatatct ctttagaaat cccttgaaga
    18421 ccagctaaaa ataaaatagt gttatatcct acactaagcc aaatcatcgt gatgatcatt
    18481 gatattcgta tccaaaaagg atttgttaac cactgtacac cgttaattcc tagcgcattc
    18541 aaaaatccat tgaataaccc agtcggattg aaaaaagtca tgaatacgga agctacagcc
    18601 accgttgatg taatggttgg aatataatag acagttctaa aaaatccttt tccttttaac
    18661 tgtgctgaat tcaataaaac agcaaagtaa atagctaata gcatcgttat tggaattgat
    18721 cctgccatga taatcaaaac attcgtgtaa gatttaataa acaatggatc tcggaagata
    18781 gctagataat tgtcaaatcc aacaaattca aatgagtagc caattttcat aaaactaaaa
    18841 gcaaacgaga taatgatggg aatcaaaatc gtcacaataa agaaaataac aaaaggtgtg
    18901 accaatccat aagcactttt tttatgagac gtatctgttg cttttttctt gctgttcttt
    18961 attgtcttgc ttggtaacga agattgcatc atcgttaagt cctcctaata ttttttaatc
    19021 accagttaat tttacgccgt acttatgagc aaaattttct gcttctttta gatatgaatt
    19081 ttcaaaatca cctgtttgcc aatagttata tgcagcggta gtcaaataag acgtagcatc
    19141 tgaataagtg gctggtaaaa cagtatttga tgtattttca ttgattttat tcaatagttc
    19201 atagtatttt tgtcctcctt agtagtcaaa ctttttctca gctgcttctg tttgataggc
    19261 caatgagtta gatgtagcca cgcccagctc cagtgcgttg gctaagcatt cttcatctgt
    19321 cagcataaat gtaagaaatt gttgtgccac ttgtggattt ttggcatctt tagggacata
    19381 aaaacttgat cctcctgata ctgcaccttt tcctggattt tcttttgaaa aaggaatcag
    19441 tggagccatg cgccatttgt cagatgcatc aggaaaattc aaagacatat tcgtagcata
    19501 ccagccgcca gcaacaaaca ttgcagattc ttgaaatgct ttctcagcat cttgtgcacc
    19561 gtagaaatgt acaatatctg agtcgatcat ttctttgatt aactttgcag catgtttcgc
    19621 ttctttagta ttcagacgga tatttccttc ttcatcaagc aaagattgat tctgctgggc
    19681 tagcatgttg ataaacaatt cttggtcccc agattctggc aaggcaattc caaaactacc
    19741 agttttttct tttaatgctt ttgccacctg gatatattct tcccaagaac tgatttcttc
    19801 aaaatctaca cctatttcag caaatttttt tggttgataa taacaaagtg ctggggtaaa
    19861 atcactagcc caaggaataa tcgtttcatt actcgtttgt tgacgcaaaa tattcaattt
    19921 ttgatcataa aactgatcgc catatttgtc ataaaatcca tattcatcag cactataaaa
    19981 agcatcttga aatttttcca gcacacctgc tgctgaagtg tctgccatgg agataatatc
    20041 cggcatatct tcgtgtgtta ccaattttgg ggtgatcatt tgtactgttg ctgttcccga
    20101 agctacattc acaattttta agtcaatatt tgctccagtt ttgcggttat agatttttgc
    20161 agcattttca acatagtttg tcagtttgcc gtttgcgaca tatacttcta atgtagtggc
    20221 tttttttatc attggatctg cgatgtttgc tgttacttct tcgttagttt ttccacatgc
    20281 acttaagctg aataataggg taatgtttag caaagctatc accaatttgt atcttttttt
    20341 catgtctatc ccttctttct tttcaagttc ttatataaaa cgctttcact tatgtatatt
    20401 aacggaatta gtaacacaaa tatttatata aaaaaatatt ttacttgtcg ttttggcttt
    20461 tcatttttgt tataatagtc attaattata aatagaaagc tttttatata aaaagagaaa
    20521 ggaaagtggt tcttttgtta acaaacaacc aatcctccaa tcttgtcaaa aaaacactaa
    20581 cctattccat agatacccat cttcatttat ctgctgctcc ctattttcga ctactaataa
    20641 atgaaagcgc taatttatat gctgaatttg cacataaatc tatagaacta gataatcctt
    20701 cccttttatt cattgataaa cagcaagaag tccaaatctt ttctactcaa aaggaaacac
    20761 aaacttttat cattatccag ttttattttg atgagcaatt attagcacat attacgggac
    20821 aatctttttc tatagatcaa gaaataacat ctatcattac ttttctgaaa aatgaacagt
    20881 tcaaaattga ttatctaaaa catagtaagc cagctatttc ctatgatcag gaaatcaatt
    20941 cttttttcat actatgccaa cagatgagca ttcatttgct ttccttatta gttacttatt
    21001 gtctgcaaaa aattcaattg tcttccttac caaggcatta tcaacaggaa cttgctttat
    21061 tgacaatacc ttcaaatgag aaagtcattc ctaaaaaaaa gcatattctt tattcagatg
    21121 aattagttga tccaatcata cgatatttag aagaacatct ttcagaaaat tttttgcttg
    21181 aacaattagc ccaaattttt tttatcagtc cagccagctt aaaaaaacat tttagaaaag
    21241 tgaatggaaa aagtgttatt agctatttta aagaactaaa aatggaaaaa gcaaaacgtc
    21301 tcgtgctaga aaatgaatta acctatacag aaattgcaga tatattagga tttcattcga
    21361 tccatcattt ttcttcagct tttaaaaaat atacagggtt atccccttca aagtattatc
    21421 tatccttaaa atagaaaaaa atttttaggt tttatccaca aattatttct ctatattttc
    21481 tgtctattca aaataaacaa taattttccg gcacaattat ttgctgtttt ttaccataac
    21541 atagtacgat caacgtagaa aaggagatgt ttttatgaaa gttgttgtca ttggcggtgt
    21601 agctggcggt ccttcatttg ccactcgttt ccgtcgattg aatgaagcgc acgaaatcat
    21661 tatctatgaa cgcggagaaa atatttctta tgcaagttgt gctttgcctt attatttagg
    21721 aggtgtgatc actgaccgtg actcgctgat cgaacgtaca ccagaaatat tgaaaacaaa
    21781 aaacaacatc gatgtcttta ctaaacacga agtaacagca atcgatcctt ctactaagcg
    21841 attaacagtt aaagacctat ccacaaatga agaaataaaa acagattacg ataagttgat
    21901 catctcttct ggtgctagac cagattatcc ggatattccc ggagtttttg aagcagaaaa
    21961 cggctttgtc ctccgtagtg tgacggatgc ggatcgaatc aaatcgttcc ttgaagaaaa
    22021 aaatccacaa catgtcgtca ttcttggtgc aggtgttatg ggtctggaat tagctgagaa
    22081 tttcaagcat cgcggcttag acgtgacttt aatcgatcaa ttgccacaag tcgctttccc
    22141 ttatgatcca gaaattgcta atttagttta tgacaaattg ctgaaagaag gattagccgt
    22201 tcatttagaa acaagagtta ctgagatccg tgataaaggt cgagaaatag tattatcaga
    22261 tggctccgtc ctttctgctg atatgctaat ttttgctgtt ggtgtttctc cgaagaatga
    22321 agtggtgaaa gcaaccggca tacaattatc agatacaggt cagatcattg ttgatgacca
    22381 gttacaaacc aatctgccgg acatctatgc gattggcgat attatcgaaa cgactagtgt
    22441 agtgactggt cagccgatcc aaagtatgct ttccagtgcg gccaatcgtc aaggacatat
    22501 gctggcagat attttaaatg gtacgcctat gcgctatcgc ggatatattg gtgcaggtgt
    22561 cgcaaaaatc tttgatcata cagcaagtta tgcgggaatg acagaacatg aattaaaagc
    22621 atcaggcata acaaattata aaactgtttt tatcactccc tttgaccatg cctatttcta
    22681 tccagaagct acaagattaa atctaaagct gatttttgat gcagatagcg gtcgtatttt
    22741 aggtggacaa gcatttggag aaaaaggtgt cgataaacgg atgggagaac tttctgtagc
    22801 aatcaccgga aacttgacag tctttgattt gcctgatttg gagttgcctt actctccacc
    22861 gtattctact acccgtgacc cgttgaatat agctggttat gtcgcaatca atcaaatgac
    22921 gaatatcgta gaaacgatca aagcaagtga tatacccgaa aacgatttga aagaagcgtt
    22981 ctttttagat atacgtgaac ctaataaagc accttctggc agtatctcgg caacaaaaaa
    23041 tattccaatg aatgagttac gagatcgaat caatgaaatc ccaaaagata aaaaagttta
    23101 cattactttc agaagaggat tgaataatta tacttctgcc cgaatcttgg caggtttggg
    23161 tatcaaagcg attttgattg aagaataaaa aaacgaccgc ggtgggtagc cgcggtctag
    23221 gagttatttt tacttgagga gtaaaaatga aaaagtatat agggttgttg gttggtatgt
    23281 atatagaata gaagataaat gtgaagaaat tgtgcattat ttcttcacat ttattaggtt
    23341 atagtttaag aaagtttaaa cattgcgcaa tttaattatt ttagctgttt cttttcataa
    23401 aaaaacatgt tgtgactctg agacaaatca tagtccatag tgatgtctct agagtaacta
    23461 cgcctaatat tacgaggcat catattaatc tatcagcact agtacctaaa ctagcatccc
    23521 tttcgaatat tttttcttat ataataaagt ttgctttcac tcctctaatc tcaccaaatc
    23581 gactggcttg cgttgtgtga tactaggaac tgattggttt agaacgactt ttctattgta
    23641 atcatatttt tcgccatcct cgttgtcttc taatccttca atgaatgatc cctaatgtgt
    23701 gtattaaata atttaatttt tttgttccta tttatttaa
//
LOCUS       DAXLPQ010000040        23359 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.040, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000040 DAXLPQ010000000
VERSION     DAXLPQ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.040"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            125..322
                     /locus_tag="ACF3UO_001882"
     CDS             125..322
                     /locus_tag="ACF3UO_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFD3657879.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            324..635
                     /locus_tag="ACF3UO_001883"
     CDS             324..635
                     /locus_tag="ACF3UO_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3657880.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            739..885
                     /locus_tag="ACF3UO_001884"
     CDS             739..885
                     /locus_tag="ACF3UO_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFD3657881.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            961..2208
                     /locus_tag="ACF3UO_001885"
     CDS             961..2208
                     /locus_tag="ACF3UO_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3657882.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            2223..2975
                     /locus_tag="ACF3UO_001886"
     CDS             2223..2975
                     /locus_tag="ACF3UO_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3657883.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(3678..3893)
                     /locus_tag="ACF3UO_001887"
     CDS             complement(3678..3893)
                     /locus_tag="ACF3UO_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFD3657884.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(3912..4148)
                     /locus_tag="ACF3UO_001888"
     CDS             complement(3912..4148)
                     /locus_tag="ACF3UO_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFD3657885.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            4406..6559
                     /locus_tag="ACF3UO_001889"
     CDS             4406..6559
                     /locus_tag="ACF3UO_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFD3657886.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            6528..7943
                     /locus_tag="ACF3UO_001890"
     CDS             6528..7943
                     /locus_tag="ACF3UO_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFD3657887.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            7976..9010
                     /gene="sppA"
                     /locus_tag="ACF3UO_001891"
     CDS             7976..9010
                     /gene="sppA"
                     /locus_tag="ACF3UO_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFD3657888.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            9012..9533
                     /locus_tag="ACF3UO_001892"
     CDS             9012..9533
                     /locus_tag="ACF3UO_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFD3657889.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            9530..9916
                     /locus_tag="ACF3UO_001893"
     CDS             9530..9916
                     /locus_tag="ACF3UO_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFD3657890.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(10412..10484)
                     /locus_tag="ACF3UO_001894"
     tRNA            complement(10412..10484)
                     /locus_tag="ACF3UO_001894"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10449..10451),aa:Lys,seq:ctt)
     gene            10865..11434
                     /locus_tag="ACF3UO_001895"
     CDS             10865..11434
                     /locus_tag="ACF3UO_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFD3657891.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            11421..12281
                     /locus_tag="ACF3UO_001896"
     CDS             11421..12281
                     /locus_tag="ACF3UO_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3657892.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            12471..13175
                     /gene="yycF"
                     /locus_tag="ACF3UO_001897"
     CDS             12471..13175
                     /gene="yycF"
                     /locus_tag="ACF3UO_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFD3657893.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            13180..15015
                     /gene="walK"
                     /locus_tag="ACF3UO_001898"
     CDS             13180..15015
                     /gene="walK"
                     /locus_tag="ACF3UO_001898"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFD3657894.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            15012..16328
                     /gene="yycH"
                     /locus_tag="ACF3UO_001899"
     CDS             15012..16328
                     /gene="yycH"
                     /locus_tag="ACF3UO_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFD3657895.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            16329..17198
                     /locus_tag="ACF3UO_001900"
     CDS             16329..17198
                     /locus_tag="ACF3UO_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFD3657896.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            17253..18062
                     /locus_tag="ACF3UO_001901"
     CDS             17253..18062
                     /locus_tag="ACF3UO_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3657897.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(18165..18794)
                     /locus_tag="ACF3UO_001902"
     CDS             complement(18165..18794)
                     /locus_tag="ACF3UO_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3657898.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            18964..20256
                     /locus_tag="ACF3UO_001903"
     CDS             18964..20256
                     /locus_tag="ACF3UO_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3657899.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(20332..20994)
                     /locus_tag="ACF3UO_001904"
     CDS             complement(20332..20994)
                     /locus_tag="ACF3UO_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFD3657900.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            21219..21503
                     /gene="groES"
                     /locus_tag="ACF3UO_001905"
     CDS             21219..21503
                     /gene="groES"
                     /locus_tag="ACF3UO_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFD3657901.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            21554..23179
                     /gene="groL"
                     /locus_tag="ACF3UO_001906"
     CDS             21554..23179
                     /gene="groL"
                     /locus_tag="ACF3UO_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFD3657902.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         8034 a         3665 c         4632 g         7028 t
ORIGIN      
        1 cttaaaagtg attaaattct tattcaggaa ttattttgct acgtttcaag aaggaattgt
       61 tttttgaaat ttaatgaatg ttagaataat agtctaaaaa cattaattta ggggtgatta
      121 gattatgaaa catttaaaaa ttttgtctat taaagagaca caacttatct atgggggtac
      181 cactcatagt ggaaaatatt atggaaatgg agtgtattgc actaaaaata aatgtacggt
      241 cgattgggcc aaggcaacta cttgtattgc aggaatgtct ataggtggtt ttttaggtgg
      301 agcaattcca gggaagtgct aaaatgaaaa aaaatgctaa gcaaattgtt catgaattat
      361 ataatgatat atctataagt aaagatccta aatattctga tattcttgag gttttacaaa
      421 aggtatattt aaaattagaa aaacaaaaat atgaattaga tcccggtcct ttaataaata
      481 gattggtgaa ttatctatat tttactgctt atactaataa aataagattc actgaatatc
      541 aagaggaatt aataagaaat ttgagtgaaa ttggaagaac tgctggaata aatggtttat
      601 atcgagcaga ttatggagat aaatctcaat tttaatgata cttataatat taaatatgtc
      661 tcaaaatttt ttgattagaa aaataggtat attgaatcag tgacataaaa gtatttatag
      721 tttgtagggg gaatcgtaat ggaagaaaaa aatagactaa atgctaaaca atgttcagat
      781 caagagctta aaaaaattaa aggaggtgct ggaacaaaac ctcaaggaaa accggcatca
      841 aatttagtgg aatgtgtttt ttcattattt aaaaagtgta actaaaattt tttttatgat
      901 atcctaaaat caggagggga tctcttgatt actatcgata caaaagctta tctattaaga
      961 atgttcgtgg gaaacttttt cttttttctc ttattttata tgactaatac tgatcttaac
     1021 aaaagaaaat atctttttgt atgtttattg ataccactca ctttttttgt tgaattattt
     1081 actgatgttt ccgcagctat acctataatc ggaagttatt ttatattaaa ggaaaagaag
     1141 aaaactaata tagtgctttt aaataaatta ctattatgta tgcttattga tgatttcaga
     1201 tctattatta cttccatggt tatgacgtat atgttttcat ttgaagggat aaaagggtat
     1261 ggttatgtag tattccagat aatgcttgat tctttgtttt tgctgatgtt tatttggtta
     1321 tatagaaaat tagctataaa taggattgtt gaacagtcca gttctaaact tactgctata
     1381 ttcatgattt atttacttac aattggttta tttgtttctt atgttgctca tcaatatcaa
     1441 gtatttgatc attttgtgtt tggtgtctta atatttttaa tcattcaaat gtttgttgtt
     1501 ctatttttat ttattagaat aactattagg caacgagaac aatatgaaca gcaattgaaa
     1561 agaaaagaat tggtttatct aaaaaaatat actgattcac tggaaaaaga tcaagaaaaa
     1621 tttgccagat ttagacatga ctataaaaat ttattgctga gtttaaaaga aatcgctaat
     1681 caaaaccatg attcgatatt ggaaaaagaa ataaaagaat tagagatcta ttctaattct
     1741 tatctaacca ataagtttga atatcgttat ttaaaaaata taaaaaatga atatttgaaa
     1801 agtttgttga tagcgaagct ataccaagca aataacaata agatttgttg taaattcgaa
     1861 tgtccaagta ctattattga agttcctgtt ccaatatttg actgtattag ggtgcttgga
     1921 attattctcg ataatgcaat tgaagcatct atagagagtc aagatagaga actgtctcta
     1981 gctatttacc gagatgataa acagatagaa atttcgatat cgaatagttg tagagagata
     2041 ctactctcta tagatactct aatgaaaaaa ggaataacaa caaaaaaggg acatcaaggg
     2101 ttaggtttat ctagtataga ggaaatcaat aaaaagaatc ccaatatgtt tgtgaactat
     2161 caaaacgatc cgtatcaatt tactactcaa gttattttgt tgttttgagg gaaggaggat
     2221 ttatgagtta tccaataata ttatgtgaag atcaaattat acaattaaat cagttagaac
     2281 gaattattga taatttcatt ctttttcacg ataaagtatt taagatagta ttgaaaacac
     2341 aaagtccgtt agaagttaaa aaatacctca aacaattccg accaaagcaa ggaatatatt
     2401 tcttagatat tgatttaaat catgaagtta acggtataga attagcagaa gtaatcagaa
     2461 aatatgatgt tcaagcaaaa atcattttta caactactca tgatgagatg ttacccgtaa
     2521 caataaaaag aagagttgaa acgttaggat ttgtaacaaa agatcaaaca ctagatgagt
     2581 atcgaaacga gattgttgag ttattgttat tagcgcaaga aaggatagat gcaacaaaac
     2641 aggttacgaa tcaagcattt gttttttcca taggttctca aacatttact tttgatataa
     2701 atgacattta ttttgtagaa gcttcaaaat taccacatag attatcattg tgtactaaag
     2761 atgggcagta cgaattttat ggaagaatta gtgagcttga aaagaaatat cctatgttaa
     2821 caagaattag tcgagcgtgt ttagtaaata tctttaacgt taaagaaata gattttaaaa
     2881 aacgttcact atattttgat tcagagttgg ccagaaactt tactttaggg aaagcacaaa
     2941 aaattaagga gaagttgaaa gaaagcactg tttagtggtt ttttctttag ggagattgca
     3001 tttttctaat aaaatagatt ccttcactag tgcaaatttt tctgaatcct attaaagttg
     3061 taccaatttt tatagctgtt attagttacg tgcataacag caatattagt tactggagga
     3121 atatttctat ggtctggaac caaaaaaggg ccaaatgaat agttcttttc ttgtttttat
     3181 taagtaccat aaaggggaat taaaattaaa tgtatggtgg aagatgcgaa agatttggca
     3241 aattctacta atttttagaa agtgtttttc attttttagt taaaaaattt gtcctgtcaa
     3301 gtgcaatcct atgattgtac ttgataggat ttgagataat tactttcctg tttttataaa
     3361 tttaacttgc aggaacaggc tttaatgcac atccgacaag tacattacca atacctcctg
     3421 taacggccga aataggtcct cctgcagcac caactacagc gctgcaagtc cttttgtaaa
     3481 aatatctcta ccattacatt tccaaagaat ttttatctga ctttaataaa agataaaaat
     3541 ttaatataat tataaaaact agcacaagaa gctttagtaa aaagttctgt ccattccaaa
     3601 cttttgaaaa gataaagaac atacctatgt tcgtaatcga cacaaaccaa tcttgaggtt
     3661 tgatattttt taattgttta cgcaccggtc cacatgctga atccagcacc taataaagct
     3721 ccacctacac cacaagcagc tattgcataa ggtcctccgg ctgaacaaag ttttactcct
     3781 gctgttgccc cagaaaaagt agtgcctaaa actcccacgg cactcccacc ttgaatattt
     3841 ttcaactctt ctgaagataa tataaatgtt gtttttgtgt ttttaatatg catactactt
     3901 attctccttt tttatttttt tcgagcatcc cagccagctg cagcacctcc agcgacagct
     3961 ccatataacc ctccaacaac accgcaagct ggtccgcaaa ttgctgttcc taaacctgca
     4021 ccacctactg cccctgtggt aagtccacct acaacttgcc ccaattttcc ccaagcatta
     4081 ttgcctccac caacagtttg tgcatttcca caatacttag ttcctttaca ttttgcatgt
     4141 ttaaacacgc ttctttaaat aatatttttt acggtgctac tgtaacatac gtatttgatt
     4201 aacagtaaaa atcttcctga aacttatcaa gtttattctt gaatagtaaa atttccaaaa
     4261 taaatttgat tcaggaatga aaaagttagt gttcaagaac tgttttcaaa gtttttgtgg
     4321 aattatgaga caatattttc actgtattaa agctatattg agaatttttc tataaaaatt
     4381 ttttagaagg agttgtgtta gataagtgat aaaatcattt ccttttgtgc agcaacaaga
     4441 tgaaaaagat tgtggtgttg cttgcctttc gatgatttta aaatatttta aaactgatat
     4501 cccgattcat aaattacggg acctatctgg gactgattta gagggtactt cagcatttgg
     4561 attgaaaaag acatttgaaa aattgtcttt tgattgtatg gctattcaag cagatagtga
     4621 gatctggaaa gaaagagatc ttatcttacc attaattgca catatattgg ttgataacag
     4681 ctatatgcac tacgttgtaa tttataaaac gaagggaaac gtactatgga ttgcagatcc
     4741 cgctaatgga aaaaatagaa aaacgattga agcgtttcaa aaagaatgga caggtattct
     4801 tttattacct atgcctagag aaacttatat tcctattaaa gaaaaagtag ctggattaag
     4861 ttcttttttg cctataattt ggaaacaaaa aggattagta ttccacatcg ttttagcatc
     4921 gattttcatt acgttttttg gcataggaag ctcatattat tttcaaggta ttcttgattt
     4981 tttcatccct aatcaagcac gttcaacttt aaatataatt tccattggct tgatcgctgt
     5041 ctatttattt cgggtattgt ttgaatatag tcgtagttat cttcttatta ttttaggaca
     5101 gcgaatgagt atggcaatta tgcttcagta tttcaaacat gtgttaactt taccaatgaa
     5161 tttttttgct acgagaaaat caggggaaat tatttctcgt tttcttgatg ccagtaagat
     5221 tattgatgct ttagcaagtg ctacgttatc aatattttta gatattggta tggtgttgct
     5281 tgttggggtt acgttagcta ttcagaatag tacgttgttt ttaatcactc tatgctcttt
     5341 gcctttttat gtagttgcaa tattcgcttt cgtgaaaagc tatgaaaaat cgaacaggga
     5401 agaaatggca gccggtgcag ctgtaaattc tagtatcata gaaagtctta aaggaataga
     5461 aacaattaaa gcatatagcg gtgaagagaa agtatataac cgtatagacc atgaatttgt
     5521 taaattaatg aaaaaatcat ttcgtacggt tacgcttgat aatattcaac aaggaattaa
     5581 acatttgatt caattaatta gcagtgcatt aattttatgg ctaggttctt attttgttat
     5641 ggataataga attagtctag gtcaacttat cacatacaat gctttactag tatttttgac
     5701 agatccttta caaaacatta ttaatttaca agtgaaaatg caaacggctc aagttgcaaa
     5761 taatcgttta aatgaaattt tcgcgattga ttcagaaaaa tcgaaccagt cttttgaata
     5821 tatgctttct gaacaattat ttcaacaaga tatcactgta aaaaacgttt cattctcgta
     5881 tagcatgaag gccccaacgt tgaacgaaat ttcatgtaca attccttcgc acagtaaaac
     5941 ggctatagtt ggagttagtg gttctggaaa atcaactctt gcaaagttat ttgttcgttt
     6001 ttatgaagca tcagaaggat cgatccatta tggaaacatt aatcacttag acattccttt
     6061 tcagatatta cgcgatcgag tgacatattt gcctcaagag tcatttttct ttagtggaac
     6121 aatcattgag aatcttatat tcggtttaga tagcccacca agtttcgaac aaataataga
     6181 agtttgtgag atagtccaac taaatgaatt tattaatcaa cagccattac gttacgagac
     6241 attgttggaa gaaggtggaa ataatctttc aggagggcaa cgacaacgat tagccttagc
     6301 acgggcttta ttaaaaaatc cggacatatt aattttagat gaagcaacta gtggattaga
     6361 taccttgtta gaacatgcaa ttatgaatta tctcctcaat ttaaaagaaa aaacgattat
     6421 ttttattgcg catcatttac caatagcaaa agcatgtgat caaattttag ttctccatga
     6481 agggcatttg gtagaaaaag gaacgcacga tgaacttcgt tttgccgatg gtatctatca
     6541 aaaattatgg gaaatctagg agagggaaac aatttatgca gaataataat tggttcgaac
     6601 attctagtat ctatactaaa caacatcata gcttctaccg ttgggtgtta taccctgtaa
     6661 ttcttttttt atgtattatt ggattgtttt taacctttgc taaaaaagag gttgttattc
     6721 ggacaacggc tcaattgaac cccgaaaaaa tagagaagtt acaagtgcca ttagaagcta
     6781 aaataatgga aaacttccta aaagaaaatc aatttgttca taaggacgat gtgttggtta
     6841 gattggattg ttctttaata gagaatgaaa aggctcagat agaacaagaa aaccaacgta
     6901 ttactcaaca aataaagatg gctcagctat ttattgaaag tataagtaaa ggaaaaaatt
     6961 tgttttcaac ggatgacagt tttggctaca gtaatcaatt aaagagcatg ttgtcagaaa
     7021 aagaatcact ccgctacgct ttgaagcaaa gtgaattaaa tgatcaaaag caattagaag
     7081 tatacgaaaa gacaaaaaga caactagaaa aacaaattga gagttcagat agtaaattac
     7141 aagaatggca acaagtacag gtagcttgga gtaataatca atcattaaaa gatttttcaa
     7201 aagaaatgat ggcaaactat gagaattggc aagaacaact aaataatgtt tctgatgatc
     7261 aaaaaaatca agtgaaactg acaatttcag caagcataaa tgaacaaatt gagcaactaa
     7321 aaaaagaagt agaacagtat cagtcagaaa aagctaaatt agttaaacca actacttctg
     7381 agaatgacag aattagtcaa acggaaaaag gaaagcaaga gctagaacaa gcaataacaa
     7441 ctgtaaaaca aacagttaca gagctaaatg aaaaacaaga gaagaaccag tcagttatca
     7501 aaagtttgga cgatcaactt tcaaaaggaa tactaaaagc tcctgtatct ggaacggttc
     7561 atttaaatga agaaacaaag ggacaagcag aactagccaa aggaacagtg cttgcagaaa
     7621 tttatccgat ccacgaaaaa tcaaaaatga aatttacagc acttttacct gcgaatgaaa
     7681 gtacctatat taaagaaggg atgaaggttc attttaaatt ggatcaaaaa ggtggggctc
     7741 cgattacgat cgacggaact ttagatgaaa tttcagaaaa ttctactgcc actgagaaag
     7801 gtgtttttta tgcagtgaaa ggaacgttaa aaacaactca atcgtttccg tttcgttatg
     7861 gattaactgg agagttgtct ttaattgtag gagaaaaaac atattggcaa caaattgtcg
     7921 atgtgtttct aaataaaaaa taattatttt tactaagaat ataggaggag tttatatgaa
     7981 taaaagaaga tggattgctg tgggagtagc gtgcggatta ttgttactat ccattatcgt
     8041 cgcgctaatt ccaggaaaag ataaagagga agcatcaaat acaaccctaa caggaataaa
     8101 taagattttt tacggatcta acgaaatcac agaagaaacg ttagaagaag gcgcatcaaa
     8161 taaaaagatt gtcaaactat ccgtcaatgg agttattgca gatacaggtg aaagcaatct
     8221 ttttagtagg gaacaatata accatcagaa ttttttaaca cagctaaaga aaattcaaga
     8281 agacaaagcg gttaagggag tgttattaga agtaaattca cctgggggag gaatatatga
     8341 aagtgctgag attgctaaag aaatggcaaa aattaaaaag ctagatattc ctatctatac
     8401 tgcatttaaa aatacagcgg caagtggagg gtactacatt tctgctggtt cagataaaat
     8461 atttgctacg gaagaaacaa caactggatc aattggtgtc attatttctg gtttaaatta
     8521 ttctggctta ttagaaaaac ttggcgtaac tgatgcgacg tataaaagtg gtgcattaaa
     8581 agatatgatg tcacctcaac acaaaccttc agaggaagag aataaagtta tacaggaatt
     8641 tgtgatgagt gcttatgatc gttttgtcaa tgttgtagca aaaggaagaa atatggatac
     8701 taatgcagtg aaagaacttg cggatggaag aatttatgat ggtaaccaag cagtagaaaa
     8761 tgggttggtg gatcaaattg gttactctga agatgcatta gattccctaa aaaaagagaa
     8821 gaaattaact gatgcgacgg ttatagaata taaaaatgac acaactggct ttgcttcttc
     8881 ttggttaggt aataagattg ctgaatggca agggctaaag gcaactacat cagatcgtgt
     8941 aatttcagtt tttgaaaaac ttggattttc tgatactcca aaaccaatgt attactatgg
     9001 agggctataa aatgaataag aagagtggca ttgaaacttt gcctaattat gtatttgcgg
     9061 gattttggtt acgatttttt gcttttctta ttgatttaat ttgtattagc atcatcaccc
     9121 atgctactat aggtctcttt tacaaaatca tgggactgga atctgacaaa tccattatta
     9181 ctttttatgg tatagcgtca ttagctattt atttaaccta ttttgtactt ttgactaagc
     9241 tgaattcagg acaaacaatt gggaaaatga tttttgggat aagagtagtg agctttgagg
     9301 aaaaagagct aagttggcaa actatcttta ttcgtgagtg tatatgtagg tttatattaa
     9361 aaaattttgt atttcaaatt gggtatttgg tggctgcttt cacgcccaag aaacaacata
     9421 ttggggatta tttttctaac acgtcagtgg ttgttattcg ttcattagaa gctattaact
     9481 atggtcaaaa aatttctaat tctaaaacac ttaatctgga gagaattaaa tgaataagag
     9541 aaaaacagag tttattttga ttttaattag tggaataaca gggattttat gtagtctttt
     9601 agcattgatg ggtggtatgt ttctatcttc tattgattca actactttaa atactacaga
     9661 actaaccagt aaggatatag atatgttagt caatctaagc gggaatgttg ttttatttgg
     9721 aggaattacc ctagtttttt cgataatgat tttcataata ggttttttag taagaaaaaa
     9781 tcaaaaaaca gtggtctatg gtattagttt actcatttta tctattattc cattttttct
     9841 tttaacatta ttgtgggtaa ttcctggagt tttaggtatt attgcgggat tgatgcttct
     9901 aataagaaaa tcttaattag gcaatgtgta gacaacgtga aacgattaat caattaaaag
     9961 ctaaatacgt tttgagaaat gataacttgt agtcgatgga agacatgtag ataaaaaaac
    10021 tacgtgtctt ttatttattc taattttttc gaaaaaaaga cactctctga ttgttgtatt
    10081 aatggaaaag gggaaagcag caagtaaatt tagtttttct attaaatatt cttcactttt
    10141 taacctttta tagtacttag atttaatcct atatgtttag agagttcatt ggcagcatga
    10201 ttttgcaaag cttctcgaat tattgttata ttagaaactt tactgttcat aattatgctt
    10261 cttttttaac tcaaagtcca aagggctaca gtggactttg agttaaaaat aaaaagccct
    10321 agttattttg aaaaataaaa aaagaacagc gtaaatgttt tcgaaatgct ttcgcaccaa
    10381 catttacctg ttccgtgggt ttggcaccca atgggccgtg aggggctcga acccgcgacc
    10441 cgctgattaa gagtcagctg ctctaccaac tgagctaacg gcccgtacaa aaagtactta
    10501 ataatagtag cactaagaat tttaaaatgc aagactacat ttaaagaaaa tcagaaaaat
    10561 ctttacttcc ttataggaaa tcattcatag attattcaca tttgctcgct attatataag
    10621 cataccaaca aacaaagttc ttgcaagaga acaaacccta acactttttt cattttttac
    10681 tcctttcccg ccgtctcccc ggcgggtctc ctgttcttaa cgataaaaga caagaaggct
    10741 tagccttctt gttttttgtt ttcatagaat cccgctaatc aaatcaccta gttaaagcaa
    10801 ctagattgaa tgtttatcat aagtctgata tcatgtttat gaaatgaaaa aaggagcggt
    10861 tatgatggaa aaaatgcgtc agcaattaat ggagtggggg aaggaactag aaacattccg
    10921 tctgcctcac tgggaagaac tccctgactt agaactttat atggaccaag tcagaacgtt
    10981 agttgatcgt tatctttcac ctgtgataca aggagaaaag catccattgc ttacctcttc
    11041 tatggtaaac aattacgtta aactaggttt gataccagca ccagttaaaa aaagatataa
    11101 caaagaacac gtagcatttt tacttgcaat cactacgttg aaacaagtat tgactattcc
    11161 tgaaatcaaa gaagggatat tgttccaagg aaaaacagta ggaattcgtg aagcctataa
    11221 tctattttgc gatgaacaag aagcagctgt gtggatggtc agccaattag cacaaggtaa
    11281 atctcatccg caaaaattcg accaggcaac ccctgtagaa tatattgctg taagagcggc
    11341 aactttatcg tttgcaatga aacttcttgc ggaaaaaacg attgttctag aaaccgaata
    11401 tttaaaagag gagaaaacaa atgaaaaaca ataaaatcgc aattttagta gattcaggta
    11461 cggatgttcc agaagaattg ataaaaaaat acgagatgta tatgatccca ttgaaaatta
    11521 tttataaaga tcaggtatat acagataaaa ttgacattac ccctgaagag atctatcaac
    11581 gtttgccaga ggaaatccct ggtacatctt tgccggatgg tgagtcgatc acagaaatct
    11641 ttgagcaaat caaaaaagac ggttatgaaa aggtacttgc ggtaacaatt tccagtggat
    11701 tgagcgggac atataatgtg gttcgtttaa ttgcacaaca gcaagaagaa ttggaagcat
    11761 atgtactaga tacgaaaaat attggtattg gtgcaggttt ttctgcgatc caagcagcaa
    11821 aatggctgga agaaggagta gaatgggatc aactgatcag taatctgaat gagttagtcg
    11881 aaagaacaaa agttttcttt aatgttgcga cattggaata tcttcaaaaa ggtggacgga
    11941 tcggtttagt tgcttctatt gtaggaaccg ctttaaagct taacccaatc atctcatgta
    12001 atgaagaagg gatttattac acagtaggaa aagctagggg acgtaaaaaa agtttggata
    12061 aaacggttgc ttacgtcaaa gaaaaaatcg gtaatgcaaa ggtcttcaac ttagctgttg
    12121 cccatgggga tgcgaaagaa gaagcaattg aaatggaagc gagacttaaa agagagttcc
    12181 cacaagcaaa ccaaatctac tttggccaga tttctccggc attagtagtc cacactggtc
    12241 cgggattatt gggtgtcggt gtacaagttt tagaaggata aatcaaaaaa aggaaacact
    12301 gaggtgaaaa tcagtgtttt ccttttttat tgaagttaga acaaaaaata ataaagtatt
    12361 ttgcactttc attttaattt tctcttttgt tttataggca aagatgaaac aaaagcagaa
    12421 atacggtata atgagaaggt atgacaataa tatataagag gtggctcttt atgaaaaaag
    12481 ttttagttgt cgatgatgag aagccgattt cggatatcgt caaattcaat ttagccaaag
    12541 aaggctatga cgtttatact gcatatgatg gggaagaagc cttggaaaaa gttgctgagg
    12601 tagaacctga tttgatttta cttgatttga tgctacctaa aatggacggc ttagaagttg
    12661 ctcgtgaggt acgcaaaact tatgatatgc cgatcattat ggtaacagcc aaagattctg
    12721 aaattgataa agtcctaggc ttagagttag gcgccgatga ttacgtgacc aagccatttt
    12781 ccaaccgaga attagttgca cgtgtcaaag caaatcttcg tcgcggtgcc acggctgcga
    12841 aggaaccaga agaggcagca cctgcggaat tgacgattgg tgatttgacg atccatccag
    12901 aagcttacat ggtgacgaaa cgaggagaaa caatcgagtt aacacatcgt gaattcgaac
    12961 tactctttta cttggcgaag caccttggac aagtgatgac aagagaacat ttattacaaa
    13021 cggtttgggg ttatgattat tttggagatg tacgaacagt ggatgtaact gtacgtcgtt
    13081 tgcgtgaaaa gatcgaagat aatccaagcc atccaaatta tttagtgaca cgtcgtggtg
    13141 tcggttacta tttgcgtaac ccagaacagg agtaattgga tgaaaagaaa agtccgcttt
    13201 tttcgatcag tcaattttaa gatcgctatt acctttattc tgattttatt gatctcgatc
    13261 gaaattattg gtgcctactt tatacgtggt ttagaacgtt ccacgatcaa tacatttatt
    13321 aaagatatga atcaaacggt ggaatcatta gcaacaacaa tcagcccgga attgaatcga
    13381 aaagataatg cagatgatga agaggtaaat gcgaatatca aaagatttat tgaaaacagt
    13441 gcgactagcg atatcatcga aatacgggtc gttgacgaaa aagggatcat ccgaggaaca
    13501 accgatgtca atgaacaaag cgctgtggga aagaaaaatg attatgttga tatcaatgat
    13561 ttcacgacta aacgttatgt tgctttagat aacgacgata aacgggtgaa tatcaatgtt
    13621 caaccgatcc tgtccccgac cggcgatgcc gttatcgggg ctctttacgt caaaagtaat
    13681 atcgaacaaa aatattcgga aatcaataac acagcagtca ttttctttac tgcctcacta
    13741 attgcggcat ttatttcaat gatcgtatct gttttagttg ctcgttcgat tacacagccg
    13801 atcggtgaaa tgagagaaca agccattcga atcgctagag gagactacag tcggaaagtc
    13861 aaagtgcatg gacaagatga acttggacag ctggctgata ccttcaatca gttagctgaa
    13921 cgtattgaag aagctcaaga tacaatggaa gctgaacgca atcgtttgga tagcgtgcta
    13981 tcccatatga cagacggcgt cattgcgaca gatcgcaggg gtaaagtcat tacgatcaat
    14041 gatatggctg tttccttgct agatatcaaa aacgaggaag caatcggaca atcgattttg
    14101 acacttttag atatcgaaga agaatatacg ttgcggaaat tattagaaga tccaaacgaa
    14161 atggtacttg accgttcaac cagtacattg gaaagtgatc agatgatctt gcgagtagac
    14221 ttttctatga tccgtcgcga atcaggtttt atcagcggat tagtagctgt cttgcatgat
    14281 gtgacagaac aagaaaaaac agaacgggaa cgtcgtgaat tcgtctctaa tgtttcccat
    14341 gaacttcgta caccgttgac aagtatgcgt agttatatcg aagcattgag cgaaggtgcg
    14401 tggaaagacg aggaagtagc accaaatttt ttgaaggtaa cgctagatga aacagaccga
    14461 atgattcgaa tgatcaatga cctcttaaat ctatctcgca tggatacagg taatacccag
    14521 cttcaattag aatatgtcaa tttcaacgag ttagtgaatt ttgttcttga ccggtttgat
    14581 atgatggtgg gaaatcagga aaaaaattat aagatccgtc gtgaatttac gcaaagagat
    14641 ctttgggtcg aagtagatac agataaaatc atccaagtag tcgataatat catgaataac
    14701 gcgatcaagt attcaccaga tgggggaacg attacttgtc gcttattaga aacgcataat
    14761 aacgtgattt taagtatcac cgatcaagga ttggggattc ctaaaaaaga tctgaaccga
    14821 gtgttcgagc ggttctatcg agtagataaa gcacgtgcaa gagcacaagg tgggacagga
    14881 cttggattag ctatttctag agaagtgatt aaggcgcatc gaggcgctat ttgggcagag
    14941 agcaaggaag gaaaagggtc gactttttat atctcgctgc catatgaacc ttatgaggag
    15001 gaatggtggg aatgagaatc tctgaaaaag tcgttcgtat aggactcatt ttgatggttg
    15061 cgttaagcat atacttctct tatgcaatct ggctgagccc agcaggaaaa agttcaatca
    15121 acgtagatga gacaaacact caaatgatcg agtctcaaag caatcgaaaa acttccgaag
    15181 tctttcttcc gcttcatgtt acatggcacc attcgggaat gatccaagaa accaacagtg
    15241 aaaatctcgt gtaccgattg caattgatca tcgataaagc aagatttgga aagctttctg
    15301 aagtagtttc aggagacaaa tcacagtttg aacaggtgaa aaatctgaac tctggttttg
    15361 agttggccta taatgcgcct tttttgctaa gagaatacaa ggaagcattt gatttagatt
    15421 tagatgtgtc gaacttggca aaagaaagcg aaaatatgta ttttactaga atacaattcg
    15481 atcaaggaaa taaaaaaatc cgatttttga attattcgaa ccatctcgta tatgaagcaa
    15541 atatttcgtt gaattggaca gatatcaata aagaattaac agcaaaagac acaaaatgga
    15601 cagaaatgac aacagaacca tcgacgatcg acacgcaata tgctacgaaa cattcgatca
    15661 aactgaagaa gtatagttat atcctgtcac agcaacccta tacacttttt agaaatgctt
    15721 ttttccagaa accagatagc gtgaaaaata atgatgaaag caatgaattg attttttacg
    15781 gtgggaatga aacaatgtct atccattcgg aaacgcaagt agttgatttt cgtggagagc
    15841 tgccagagaa aaaagaaaat gctagtgtat tttctgaaag tttcccctat attagcaaat
    15901 taggcagttc tttagggaac ctcagatatt ttgaccgcag tgacaatacg atcgattatc
    15961 ggatattcgt ggaaggcttc ccggtttttg ggacagacag cagaggacag attggtgtgg
    16021 aagttggcgg tgaaacgaat ggttctgtgc aagtgaatat ccaaaccagt ttgaatacga
    16081 ttcaagtgcc gataccttca gacgaagaag tagaacttgc aagtacgaat gaaatcatcc
    16141 agcagttaaa agctaaggga gcagatagca acaagattgg ttcagtgatc gttggctata
    16201 catggcaaaa tgtcaaagaa acgaatcgtg tcgttgatct cttacctgaa tggtatgtga
    16261 aatataaaga taactggtat tcagctaacg accttctgga aaaattacct ggattggagg
    16321 cgaattaatt ggatttcaaa aaaatcgaat ggatattttt cgtcgctttt ttagggttga
    16381 atgtgttttt attcagcagt tatcatgacg cggtatacca agaaaacaat gtcattcgct
    16441 ctaatcagac tgaatcaatc caacaacgtc tggctagcga cgatatcact tacacgggga
    16501 agatttcgtc tgagaacaag caaggctatt atcttagcgc ggagcagacc aatcttagca
    16561 cttcattagc gaattatcgc aaggctggta aaagcggctt gctggcaagt ggtgtgtttt
    16621 tagacggtga tgttttgacg aaatctttat ccagttcaga tgctgaaaag aacgtgatcg
    16681 atccagataa aattagtagt tccttggaag attttttatc taacaaagac aatattttat
    16741 tcggtaatga ttatgtgtac acgaaaaact tttctcattt agaagaagaa ccactagaaa
    16801 tccaagcaag ccaagagtat gaaggcatcc cattcaatga tgatacagca aaaatcgttc
    16861 tttctttaga aaaaaacgat aatgattata gcatcacgaa atacatgcag acgcatttat
    16921 ctgatatcga gcagctgcgc gaaaagacgg aactgtatac ggaagaggaa gcaatcaata
    16981 cattgtacat caataacaaa ataccaagag gatcaaaaat tttatggcgt cagctagctt
    17041 attcctgtat tctgaaagtc cgggaaaaaa atgtgtatgt tcctgtttgg catgtagcga
    17101 tcgaaacaag cgataaagtg gtccaaattg agagcgtcaa cgctttcagc aatacgatcg
    17161 tgacaaacaa tactgtacca aaagtggaag atcaataaaa aagcgagtat aatgaaaaaa
    17221 gtttacaaag taagaaggga agtaggagtc aaatggctga agaaaaacca gcttttaaaa
    17281 tcagtatcct agcaagtgga agttcgggta attcacttta tatcgaaagt gaaaaaaaac
    17341 ggcttttggt cgatgcagga cttagcggta aaaaaatcac ttccttgatg gctcaaattg
    17401 atcggacacc ggaccaatta gatggaatac ttgtgacgca tgaacatcga gatcatatac
    17461 atggcgtggg tgtcttggct cgtaagtatc atttggatgt ttttgccaat cagcagactt
    17521 gggaagcgat ggaaccactg attggaaatg taccagtgga acaaaaacat ctatttgaga
    17581 tggggaaagt cagaacattc ggcgatatcg atattgagag tttcggcgtc tcccatgacg
    17641 cagcggctcc gcaattttat cgtttccata aagaaaatcg gtcattcgtc atgttgacgg
    17701 acaccggata ttgcagtgat tatatgcgag gtgtcattga aaatgccgat ggttatttga
    17761 tggaaagtaa tcatgatctt gagatgttac gcatgggacc ttatccgtgg aatttaaaac
    17821 agcgtatttt aggagataga ggacatcttt ccaacgaaga cggtgcactt gtcatgactg
    17881 atgtgatcgg taatcggacc aaacgaatct atcttggcca tcttagcaag gaaaacaata
    17941 tgaaagaact tgctcattta acaatggaaa atgttttgaa agaaaaagat tttggcgttg
    18001 gacatgattt tgaaatctat gatacagatc cagatgaagc aactgagcta ttttcgattt
    18061 aaacagttca atcaataaaa atataaaaag cagaagataa aatcaatcag ggttggtttt
    18121 atcttctatt tttatttttt tagcatatta aaaaaataac cgtattatcg actgactaca
    18181 ctgatgtgct gcttttcatg tttctcatcc agtatctcat ctactaatgc aatcgcgtaa
    18241 tctgccatgc tgatcgtact gtcgctagca gcgtttcttt gtaaataatc atcacttaac
    18301 aaataagtac ctgtacgttt gccatgtgga tcaaataaag aagctggact gatataagtc
    18361 caatgtagat ttttagattg tttcaatttt aacaatcctt cgtacatatt gaaagctgtt
    18421 ggatagaagg gtgcattttt aggtacttgg tcaatcatac gagtcgtctt ttctgtatct
    18481 aagaataacg aagaggcacc cccaacgaca attaagcgtg tatcggttcc ttcaagcatc
    18541 tcaatcaaat gggacaaaga agtttgatgc atttcttctt ttcctttggg agcgttgaaa
    18601 gcatcaacga caacatcaaa agatgcaaga tcagtagttg tcaactcaaa taaatccttt
    18661 tgtataaacg gaacatctga tggcaatttt tctggatgac gcacgattgc cgtcacgtct
    18721 aaatctctgg acaatgcttc gtctaaaata aatgaacctg catggccagt agctccaatg
    18781 agtgcaattt tcataaaaaa cctccttttt tattcctgtc cattgtaagc agttgctgaa
    18841 tattcgtcaa agaatccgat ttttgaaaag ctcagtgcgc attcctttca tggttcgtga
    18901 tcattgggta tagttaaatt aagaaaactg attgataaaa atagaagttg aaggagataa
    18961 gaaatgaaag agtggttaga tcgtgccttt ttaccaatga taacatctgt tgtgaatctt
    19021 agacccttaa ctgctttgcg taatggaatg acttacacga tcccaataat tattgttggc
    19081 tcgctgtttt tcttatttgc tcattttcct gtggattaca tcgctcagtg gatagacaaa
    19141 acaggatttt ctatgtattt tacacaagta taccaggcta catttgatgt gatagccttt
    19201 tggatcgttt ttgccattgc atacgcttat gcaaaagaag aagacatcga tcgcttacca
    19261 gtcggcataa cagccttgtc tgcttatcta ctgcttattc agccactaaa tactcagata
    19321 gatactgtct ggacaggtgc tgaagggata ctaggagcag ttacaactgg gctcatcatc
    19381 ggatggggct atgcacgttt agtaagactt gcgaaagggt ggaagcaaag agagaagata
    19441 cctgaaaatg tttggcagtc ttttacttca ttgattccaa tcattgttat agtcactttt
    19501 acgcttatcg gttcagcggt ttttcaacat ttgttcagaa tgactgttgt tcaaggagta
    19561 tggacatatg tccagcttcc cattcaatcg ttcatagaca cgttgtttgg tgtgctttta
    19621 ttaggttttt ttgttccgtt tttatggtta tttggtcttc atggatctgc gatggtcaat
    19681 gggttggtta gtcccgtctt gcaagcgaat tcattagcaa atgcagaaat cttagcctca
    19741 ggacaagagt tgacggtggc aaatggcgga catatcgtta ctcagcaatt tctcgatcag
    19801 ttcatgacgg ttacgggtgc tggattgacg ttaggggctg tattttttat gacggttttt
    19861 gcgaaatcga agaaatacag agaattagga aatcttgctc ttttaccagc ctttttcaac
    19921 atcaatgaat caattatttt ttccacaccg atcgtgatga acccgatgat ggctgttcct
    19981 tttattttcg caccggtcgt ttcaggattg attacctatt ccgctttata ttttggattc
    20041 gttcctttat ttacagcagt ccaagtccct tggacaacac cgccgatcct ctcgggtttc
    20101 ttagtaggcg gagtgcctgc agcgatttta caaggtatcg tgttgtcaat tagttttttc
    20161 atttatttcc catttttgaa aaaaatagat tctgcaaact gcaaaaagga aagacagaca
    20221 aaaaatgatg gagcagcaga aaagatgaac gactaaaaaa caaaaatact cctgtcgctt
    20281 tagattggga aaatcaccaa tctaggatga caggagtatt tatagtcatg tttatactag
    20341 ccctttttgg acagctaatt gaacaagaac aactaatgtg ttcattccta cgtgtgtgat
    20401 catcgatgtc cagatccgac cagttgcttt gtactctagg ctgaagaaga aacctaggaa
    20461 aaagtagatt agcagatgac catcattatg agcaaacgca aacagcaaag agctgatcac
    20521 tgctccgacc caaaaatttg aatatcgact gatgatcccc agtatactgc ggcggaatac
    20581 gaactcttcc atgatgggtc cagcaacagt tgtcgccaaa ataaaagcgg gtgcttccat
    20641 gatcatctgg atgatatttt gtgtattctc ggaaggggtt gctttgccaa acaatacaga
    20701 ttctaacatg acagcgatgc tttgcagaat caatgcgaca aagattccaa ccaatccata
    20761 aataacaatc tttggagcag aagctttttt taccgctgat tcgatcgcta agggttcacg
    20821 ttgcttaaaa taaaaaatag ctaggacaac ggcgcctagt atatacatga ctgcagttgc
    20881 tgtgatcaat tcagacgtag attttacaag tcctatcgaa gctaggatca agggtgagat
    20941 aaaaattaga ccatagcaaa aaatgctgag gaagctatat ttttttaaag acatgtaatt
    21001 cctcctttta agggataaca agcatgcaag gcaagcttat atcgattgat ttcaattata
    21061 tcataatttc aataagcagc tgtcagaata aaatttcttt tctttgattt aaaagcttgc
    21121 aaaaaagagg gagaatgagt attattaaaa atgtaggtta gcactcgaag gttaagagtg
    21181 ctaacagatt aaaaaaagag ttatcggagg gatttatcgt gttaaaacca ttaggtgatc
    21241 gcgtcattat cgaagtcgca aaagaagaag aaaaaactgt cggaggaatc gttttagctt
    21301 ctgctgctaa agagaaaccc caaactggga cagttgttgc agtcggtgaa ggccgtttgt
    21361 tagaaaacgg tgaaaaagtt cctgccgctg taaaagcagg cgaccaagtt atgttcgaaa
    21421 aatacgccgg tacagaagta aaatacgaag gaaaagaata tctgatcgtc gcaggaaaag
    21481 atatcatggc gattgttgag taaatttgga agataaaaaa ataatcaaaa ataatcaatg
    21541 aggtgaatca atcatggcaa aagaattgaa atttgcagaa gacgcacgcg cagctatgtt
    21601 acgcggggta gataaattag cagatacagt gaaagtaaca ttaggaccta aaggccgaaa
    21661 tgtcgtacta gaaaaatctt acggctctcc attgatcaca aatgatggtg tgacgatcgc
    21721 aaaagaaatc gaattagaag atcattttga aaacatgggt gcaaaacttg tatcagaagt
    21781 agcatcaaaa acaaatgata ttgcaggaga cggtacaacg acagcaactg ttctgacaca
    21841 agcaatcgtt cgcgaaggtt taaaaaacgt aactgcaggt gctaatcctc taggcattcg
    21901 tcgcgggatc gaattggcaa caaaagcagc agtcgaagaa ttgcataata tctcaactgt
    21961 tgttgattca aaagaagcca ttgcacaagt agcagctgtt tcttcgggtt ctgataaagt
    22021 tggacatttg attgctgatg caatggaaaa agttggaaac gacggtgtca tcacaatcga
    22081 agaatcaaaa gggatcgaaa cagaactaga tgttgtagaa ggtatgcagt ttgatcgtgg
    22141 ttacttatca caatatatgg taacagataa cgacaaaatg gaagctgttc tagaaaaccc
    22201 atatatcttg atcacagaca aaaaaatctc taacatccaa gatattctgc cattgttaga
    22261 acaaatcttg caacaatcac gtccattgtt gattattgct gacgatgtag atggtgaagc
    22321 attgccaact cttgtattga acaaaatccg tggaacattc aacgtagtag ctgtaaaagc
    22381 tcctggtttc ggcgatcgtc gtaaagcaat gcttgaagat atcgctattt tgacaggtgg
    22441 tacagtaatt actgacgatc taggtttaga attgaaagat gcaacaatcg aaaacttagg
    22501 aaatgcttct aaagttgttg tagataaaga caatacaacg atcgtagaag gttctggaga
    22561 aaaagaagca atcgaagctc gtgtgcaatt gatcaaaaac caaattgctg aaacaacttc
    22621 tgattttgac cgcgaaaaat tacaagaacg cttagctaaa ttagcaggtg gtgtagctgt
    22681 tgttaaagtt ggtgcagcta ctgaaacaga attgaaagaa ttaaaattac gcattgaaga
    22741 tgcattgaat gctacacgtg ccgcagtaga agaaggaatg gtctcaggtg gtggtacagc
    22801 tctagtgaac gttatcagca aagtttctgc tgtagaagca gaaggagacg tggcaacagg
    22861 tatcaagatc gttgttcgtg ctttagaaga accaattcgt caaatcgctg aaaacgctgg
    22921 ttatgaagga tcagtgattg ttgataaatt gaagaacgtg gaactaggca ctggtttcaa
    22981 tgctgctact ggagaatggg taaacatggt tgaagcaggt atcgtagacc caactaaagt
    23041 aacacgttct gccttgcaaa atgccgcttc cgtttctgcc ttgttattaa cgacagaagc
    23101 agtcgttgca gataaaccag aaccagcagc gccagcagct cctgcaatgg atccatcaat
    23161 gatgggcggt atgatgtaag aaaaagcaac ttgcttatct acaactgatc attagtgaaa
    23221 gacagataaa aagaggctgg aacagaagcg tttaactcca agaaataaga agaaattcac
    23281 ggaaattgct tttcaaattt ttgtgaattt cagcttattt ccgaaggagt tgcttctgct
    23341 tccgctgttt atacgtgtt
//
LOCUS       DAXLPQ010000041        22464 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.041, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000041 DAXLPQ010000000
VERSION     DAXLPQ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.041"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            144..542
                     /locus_tag="ACF3UO_001907"
     CDS             144..542
                     /locus_tag="ACF3UO_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFD3657903.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="ACF3UO_001908"
     CDS             526..1221
                     /locus_tag="ACF3UO_001908"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFD3657904.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="ACF3UO_001909"
     CDS             complement(1815..2702)
                     /locus_tag="ACF3UO_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFD3657905.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="ACF3UO_001910"
     CDS             2887..3726
                     /locus_tag="ACF3UO_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFD3657906.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="ACF3UO_001911"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="ACF3UO_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFD3657907.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="ACF3UO_001912"
     CDS             5194..5550
                     /locus_tag="ACF3UO_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657908.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5595..6710
                     /locus_tag="ACF3UO_001913"
     CDS             5595..6710
                     /locus_tag="ACF3UO_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657909.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="ACF3UO_001914"
     CDS             complement(6736..7176)
                     /locus_tag="ACF3UO_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3657910.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="ACF3UO_001915"
     CDS             7336..7842
                     /locus_tag="ACF3UO_001915"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFD3657911.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9922
                     /locus_tag="ACF3UO_001916"
                     /pseudo
     CDS             8010..9922
                     /locus_tag="ACF3UO_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            9927..10928
                     /locus_tag="ACF3UO_001917"
     CDS             9927..10928
                     /locus_tag="ACF3UO_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3657912.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11130..11336)
                     /locus_tag="ACF3UO_001918"
     CDS             complement(11130..11336)
                     /locus_tag="ACF3UO_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFD3657913.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11982..12830)
                     /locus_tag="ACF3UO_001919"
     CDS             complement(11982..12830)
                     /locus_tag="ACF3UO_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3657914.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12994..13896
                     /gene="gnd"
                     /locus_tag="ACF3UO_001920"
     CDS             12994..13896
                     /gene="gnd"
                     /locus_tag="ACF3UO_001920"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFD3657915.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13898..14899
                     /locus_tag="ACF3UO_001921"
     CDS             13898..14899
                     /locus_tag="ACF3UO_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFD3657916.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14896..15180
                     /locus_tag="ACF3UO_001922"
     CDS             14896..15180
                     /locus_tag="ACF3UO_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFD3657917.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15213..16010
                     /locus_tag="ACF3UO_001923"
     CDS             15213..16010
                     /locus_tag="ACF3UO_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3657918.1"
                     /translation="MGYSTNLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16024..16857
                     /locus_tag="ACF3UO_001924"
     CDS             16024..16857
                     /locus_tag="ACF3UO_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3657919.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16875..17732
                     /locus_tag="ACF3UO_001925"
     CDS             16875..17732
                     /locus_tag="ACF3UO_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3657920.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17754..18263
                     /locus_tag="ACF3UO_001926"
     CDS             17754..18263
                     /locus_tag="ACF3UO_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3657921.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18300..18701
                     /locus_tag="ACF3UO_001927"
     CDS             18300..18701
                     /locus_tag="ACF3UO_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657922.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18813..19166
                     /locus_tag="ACF3UO_001928"
     CDS             18813..19166
                     /locus_tag="ACF3UO_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657923.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19200..19643
                     /locus_tag="ACF3UO_001929"
     CDS             19200..19643
                     /locus_tag="ACF3UO_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3657924.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19660..20745
                     /gene="uxuA"
                     /locus_tag="ACF3UO_001930"
     CDS             19660..20745
                     /gene="uxuA"
                     /locus_tag="ACF3UO_001930"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFD3657925.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20738..21451
                     /locus_tag="ACF3UO_001931"
     CDS             20738..21451
                     /locus_tag="ACF3UO_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3657926.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21658..21807)
                     /locus_tag="ACF3UO_001932"
     CDS             complement(21658..21807)
                     /locus_tag="ACF3UO_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657927.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22203..22403
                     /locus_tag="ACF3UO_001933"
     CDS             22203..22403
                     /locus_tag="ACF3UO_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3657928.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7746 a         3451 c         4642 g         6625 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctt cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aagaatgttg ccgaaaactg gagaaaagaa
     9841 acattcgctt ctcatttatt caggtggatt tttatctgtt agcacgatta tcacatggat
     9901 ttggcgaaga aagagagggt aaatgaatga aatggttcaa gcgaatagtg attgcagtac
     9961 cagttatcat cgtagttatt ttagtcactg tatttttgat taatcaaatc acaccaaagc
    10021 cgattagctt gcttgttaga aaacaatttg acacaagtga aaaagaacaa gtatatgccc
    10081 gaccagatga tttccagcaa aaaatcgaac aaatcgatat aaaaaaagaa atatcctatc
    10141 cttcaaagta caaaaataat aatatggata tctacacacc gaaagtggaa aagaaaaaat
    10201 taccgattct tttctggatg catggaggcg catatgtagg aggggataaa aatgattgtc
    10261 gtgattattt ggaatatcta tgttcagaca cgcagcaaat catcgtaaat atagattatg
    10321 aacgatcacc ggaagcaaaa catcctacac cagttatcca attgaacgaa gccattcaag
    10381 cagctaaaaa agagataaaa gatcaagcag attggtcgaa tatttcgatt ggtggaaatt
    10441 cggcaggtgc acaaattagt ggagaatatt tgttagcact tcaaaatgaa gaaattaaaa
    10501 aagctgatca tcttgatccg actttggaga acaagcagat tacgaagttt atttctttgt
    10561 ctggtctgtt ggatccttct gcacttactc aagtaagtga taaaatctct agctttcttt
    10621 atgaaaaatg tggatgggct tactttgata ataaggactt tgaacaatca gagaaggtca
    10681 aaagtttagc cttggtcaga catgcggatc gttggacgca aaacacattc ttaacggatg
    10741 gaaatacaaa tacgtttacg aaacaaatgg aagaagtaac ttctgtattt gagaaagcgg
    10801 gggtgaaagt cacaaaagta gattatgcgg agaaaaatgc tgttttgaac catgaatatc
    10861 agtttgattt cagcaataaa caagcgcaag aaacatatca aaagttagta atgtttttca
    10921 aggagtaaag tcttatgatg caaaagaggt tgtaatctgt cacttagctc caagtcacaa
    10981 ggagcaattt caataaacaa gcttttcatg gtttatgaat attgtaactt gtgactgagg
    11041 agttagagat ggcaaggggc accttttatt cgaaatttgg gaatatcaca cgattattgt
    11101 cacgatctct tttacgtaaa ttttataagt cagatttgtt gttttgatcg tttaaaaaaa
    11161 gcaacaaatc cgaagcctgc ggaggcaaga agggacaaaa agccgagtgg taagcaaaag
    11221 aatgctggtt ccactaatat tccgttgtta ttgatataag gctgggaaca aagatgaata
    11281 gcaaataaaa tcaatgcact agcgaaaaaa agcaaagaaa tatggatagc tttcataagc
    11341 agcacctcct tttttataat tgtatgataa atagattaag aatctataaa tgtgacaagt
    11401 ttgttaggat gtgaataaaa tgatcatcta gcgaacttga aacaaagatg gctaatgata
    11461 agcaattaat gattcagcaa tcagataggt acaaagttta ccatcatacg tctagaccaa
    11521 taatagaaaa tatgggaata taatagaaaa gatttaggat acccccaaaa gaatttcccc
    11581 aaaaattcga tgtatcctaa acttttttat tttacataac aatcatatca actgtgaaat
    11641 aaaattacaa atgataacct aaaatgaggc caaaagccag tgttatcaag gaaatactta
    11701 attcaccaaa atttttttta attttttaga aaataagaaa caaaaataat aaaaaaaaga
    11761 aaagataaat tttttactac tgtatactaa ctttgttatc gcatctaaca agtaactcga
    11821 ataataccaa tacaaccttc tccaaagatg cgatgacata cgttctaacc caccgactat
    11881 tgatgttctg taccaccctt gcagaaccaa aaaagccact accaaatatt tggtagtggc
    11941 tttttttgtt ttatggattt ttcgcttttt ctgttatggt gctattcttt gatttcagaa
    12001 atagtatgtc gaactttagc gatagaacga cgtgattctt tttcgttgta aaacatcaaa
    12061 atcacatata gagagtccaa aatgcttagt tgagaaatac gggaagctaa agcttcagat
    12121 cggaattctg tttcttcaga aatagaaata aaaacgacat cgccaagttt agcaagggaa
    12181 gaattagctt ggctagtaat aacgattgtt tttgctccag tttttcttac ggtttcagca
    12241 atatggattg tttcttttga ttgccctgtg tgagaaatca aaacagcaca gtctttttcc
    12301 gtcaataaag aagcttccat caattgaata tggtaatccg tgctgtgaga agttgcgata
    12361 ggggaacgca aaaatttatg ataagcgtca gttgctacaa tctctgaacc gccaacaccg
    12421 aaaaaataga cacgtttaga ttcattgata atagtagccg ctttttttag atccttttgt
    12481 tgtaacaact tttttgtgtc atttaaagtt gaaatactag actcgaacac cttttgcgcc
    12541 atagtgagct cagtatctgt tttctgaata ttttcgtgga tagaaatagc agatagatca
    12601 ttttcttgga tcaacatggc cattttaaaa tctttaaatc cattataacc aagttttttt
    12661 gtaaattgaa aaaaagtaga gtcagcaatg cccagttcac ttgctaaatt gctaatagga
    12721 ctatgactta ctttgcttgg attttctaaa atataatcgg cgatagcctg ttcttttggg
    12781 ctgaagtcgt tgtacattgt tttgatttgt agtcttatgg agacgctcat gagaattcct
    12841 cattttcata ataagattat cattttttcc gttctcatta atgttaaaga tacaaggaga
    12901 gtaggaaaaa atcaaacaaa aaatattttt gtaaaatcta tttacaaaaa aatttttttg
    12961 tataatgagg gtataagaaa tggaggcgct atcatggaaa ttggtgtaat tggtttggga
    13021 aaaatgggat tgaatttagc tttaaactta aaagagcacc atcacaaagt acaaggactc
    13081 gacatttcaa gtacagctgt tagtcaggca agagaaaatg acattcctgc ttatcaagag
    13141 atctctgaat ttctagctac ttttgagcag aaaaaaatca tctggttaat gcttcctgct
    13201 ggagagataa ccgaaaacat gttaagaaaa ctttttccaa aactcggacc aggagacatt
    13261 attattgaag gcggaaactc ttattataaa gattcaatcc gtcgagcaga agagtttcag
    13321 aaaaatgaaa tcggttactt ggattgtggg acttctggag gaatcgaagg agcacgacat
    13381 caagcctgct taatgattgg aggagataaa gaaacttttc tatccgtgga acaattattc
    13441 aaagatgtag caattgaaag aggatatctg tatgctggtg catccggaag cggacacttc
    13501 ttgaaaatga tccataatgg aatcgaatat ggaatgatgc aagcaatcgg tgaaggattc
    13561 caacttgtac aaaaaagtga gtatgctttt gacttggaac aagtcgcacg tgtttggaat
    13621 catggttcgg tgattcgcgg ctggctgatg gaaatcatgg aagatcagtt aaacgaacat
    13681 cccaatttaa gtaattatcg gggaatcgtt tctgcatcag gtgaagcaaa atggacggtt
    13741 gaaacagcgc tagaaatggc tgttccagtt ccagtaattg caactagttt gttcatgagg
    13801 aatctttcac aggaagaaga tagtttttca gcaaaagtag tttcagcact aagaaatggg
    13861 tttggcggac atgaaatagt tgaaaagggt gagtaaaatg ccagattatc atatagcaat
    13921 cgttaattcc agcagtttcg gaagagtctt tccacaccac ttggaaagat taaagtcagt
    13981 tggagacgtt catttcttta ctgttgatca agagattcca ggaaaagaac tagcggagtt
    14041 acttaaagga ttcaatatca ttattgcaag tgttacgcca ttttttcgac gagatttttt
    14101 tgaaaacaaa gatgaactgc tattgatttc ccgacatggt attggttaca acaatattga
    14161 tttaaaagca gcaaaagaac accagacaat cgtatctatc atacctgctt tagttgaacg
    14221 aaatgctgta gcagaaaata atataactaa tttgttgtcc atgcttcgac gcacgacaca
    14281 agcacaagca agagtcaagg acgatcgatg ggaagatcgg gcggagttcg tcggtaggac
    14341 gctgtttaac aaaacagttg gtgtgattgg tgcaggaaat accggaagcg gagtaatcga
    14401 aattttgcgt aacggttttc gctgtgatgt tctagcttat gatccttaca aatcagattt
    14461 atacatcgaa agctttggtg caaaaaaagt agaacttcaa gaattactgg aacaatcaga
    14521 tatcatttgt ttatgtgcga atttgacaga agagaactat cacatgattt ctgataaaga
    14581 agtcgatcag atgaaagaaa atgtttatct atctaatagt gcaagaggcg ctctagttga
    14641 tgaagaagcg atgattaatg gtctgaaaag cggaaagatc gcaggatatg ccacagatgt
    14701 tttagaagaa gaaccgggac gtcaagatca tccgtattta gcgtttgaac aagtagtgat
    14761 tacgccacat atatcggcct acacaaggga atgtttagaa gcaatgggtg aaaaatgtgt
    14821 cagagatgtc gaacagatca gtcagcacct tcttcctgaa cgttctgtcc agacaaagag
    14881 caactatata aaaggatgat gaagaaaatg gtgaacggtt taaaagtgaa aacaggccct
    14941 caattttatt tatatgaaga aggtggtatt tcaaaagttt ctgatctctt gaaatcatac
    15001 ggcgcgaaaa gagtactggt cacccacgga acggtatcat gggaaaaggc gctacctaaa
    15061 ttagtatttt tgaatgacga aacgattcaa tttttttatc atcgttattc tggagaatgt
    15121 agttatgctg aagccagacg aatagctaca atcatcaaaa aaatgaaatc gatttcgtag
    15181 ttggcgttgg cggaggaaaa ctgaccgatc tagtgggtta tagtaccaat cttgcaagaa
    15241 tcgatttcgg agtcatccct actttagcta gtaattgtgc tccatggaca cctcttgctg
    15301 tcatgtataa ggagaatgga caagcagaag ggaaaacaga acacttttac agacaagctg
    15361 ctttttttat aacagatccc caattagtga ttgattcccc tgttccatat ttcattgccg
    15421 ggttagcaga tacactagca aaatggtatg aatctgagct catcttagaa caagattttt
    15481 tgcaagatga atcatttttg aagctagcac aagatactgc gaagatctgc aaagaagaga
    15541 ttttgaatca ttctgctaaa gcaatccaag atatggcaca aagaaaactg acatcggagt
    15601 tcaaacagct ttcagagatt atctttgctg ttgctggttt agttggagga ttaggagata
    15661 aatacgcaag aaatgcggca gcacatgcta tgcatgacgc tatcagtaaa tatattccgg
    15721 aaagccatcg ttttctacat ggagaaaaag tagcgtatgg gattttctat caactggcac
    15781 tagaaggtcg ctgggaaaaa atagacgagt tatatccttt gtatcgggaa ttagaactgc
    15841 cggtttctct agaacaaatg ggattatttc cgaaagataa acagataata gataaaatgg
    15901 ctgaatttat tgattcgaaa gagaaagtgc atttgattcc tatagaggta acacagaaat
    15961 cactgataca gtcaatgatg gaactggaag gttatatcag aaagatctga aggaggagga
    16021 cacatggaaa cattaagtgt agtacaaagt ttgttgattg ctttatgggt agccgcggtt
    16081 atgtcccgct ggttaggtgg aggagccacg ttgaccttac gtttttctcc tttgatgact
    16141 ggattagtcg tcgggttgat catgggggaa gttgcacaag cgatgattgt tacagccgct
    16201 ttgcaaatga tttatatggg ggttttttct ccaggaggat caatgccagc tgaaccatct
    16261 attgcagcag ctatcgcagt accagtcgca ttattagggg atctgtcgcc agaagcagcg
    16321 attgccgttg cggtgccagt cggattgctc ggaagttact tgtatcagtt tcgttttttc
    16381 atcaatactt ttttaggtaa atatacagac aaagctgtag aagatttgaa tacaaaagct
    16441 atggcccgat caattattct ttatccaacg gttgcctcat ttttattatt cgttccgctt
    16501 gttttcattg ctttatattt aggggcgcca ttgatcgctg atgtaatcaa agctttagag
    16561 ggaacagtcg ttatccacat tcttgaagta gtaggtggag ggttagcggc aatcggtatc
    16621 gcgacaactg tatacgttat cggtcgaaaa gattatctgg tctttttctt ccttgcttat
    16681 tttatgagtg ttgttttgaa atctttagat attacgatgg ttacttatgc catttttggg
    16741 attattatcg ctttgatctt tgtccagtcg caaaaaggga aacaagtaca gcctgccaca
    16801 agcaataaca attcagcatc ttttgatgac gaagatgact atgatgacgg attttaattt
    16861 aggaggaatg ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca
    16921 cgaaaaaaga tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact
    16981 cttttgaacg ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac
    17041 tttataaaga tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca
    17101 ctcaattaag ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcaaa
    17161 gagcagaaga agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca
    17221 cgaaagcggg attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg
    17281 tccaatatat ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg
    17341 cactttttcc ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa
    17401 gacaagcttt cactatgggc cgtaatgcta caggcctaat gcaaaacact ggtgttcaga
    17461 cagcgattga aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact
    17521 atgtaaaagt agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg
    17581 aaattcttga tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact
    17641 tgttctatac gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat
    17701 taattgtgct agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg
    17761 tagtcaattt agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat
    17821 ctcaaaaaag tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat
    17881 ttatgagaga tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta
    17941 caccagagaa agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt
    18001 tgatcgcaaa aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag
    18061 aattgaatat tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat
    18121 ctgtttattt aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg
    18181 taaagaatat ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat
    18241 tgaacaagtt tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa
    18301 tgaagaagaa cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc
    18361 gccgtacaaa aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta
    18421 tgagaacaga tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt
    18481 atgttggaga tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc
    18541 atgcattagg aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact
    18601 ctatattatt gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata
    18661 acaaaaatcc tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag
    18721 catttgggag ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa
    18781 cttttattcg aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg
    18841 atccgagtgt agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca
    18901 gcgtgagatc gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag
    18961 atacaccgct acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag
    19021 ttgataagtt gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc
    19081 agttcttcta tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca
    19141 atcagattat tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa
    19201 tgttggaaat catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg
    19261 aagtaattgt cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca
    19321 tccaaacatt cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca
    19381 tgctagtatt tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca
    19441 atgaactgac tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa
    19501 tgttgttaga agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac
    19561 aaattgtcaa acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa
    19621 aattagatga ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg
    19681 tatggtgaaa aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat
    19741 gggataattg gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt
    19801 gaggagttga aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta
    19861 gcgatccacg atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat
    19921 atacgaacaa tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa
    19981 ccaatttttg gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct
    20041 cttttatacg atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata
    20101 cacagccagt caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc
    20161 gctcagctgg aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact
    20221 tattttttag aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat
    20281 ccagatgatc cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac
    20341 ttgaagaaaa ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga
    20401 tctttagggg caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc
    20461 atccattttg tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg
    20521 gcacatccct ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa
    20581 gaagggttcg acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct
    20641 atgcctggat atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat
    20701 gaggcgataa gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat
    20761 ctttgatatg gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa
    20821 atcagcacaa aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca
    20881 aacagaaatg gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat
    20941 caaatggcga gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt
    21001 atatacgaaa aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac
    21061 aatcgtggct tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct
    21121 atatgccttg tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc
    21181 agagatcttt ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt
    21241 tgaagactcg attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat
    21301 caaagatcat ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt
    21361 aagtttatat gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg
    21421 atttttagaa agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta
    21481 tttattgtcc tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt
    21541 atctacctta tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta
    21601 ccagtagatg cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta
    21661 tgcagatttt tttaattctt gcactgcttg ttcgatcgta acacctgtcg ctacatgatt
    21721 ggtattttct ttgtcaaaaa cgacaaatag attcaaatct gtatccaagg ttactcgata
    21781 ttgtatatct ttgttataga atgtcatagc cattctcctt tctttaaata cttgctgaaa
    21841 ggcaacgaac gcgttgataa cgaaattcca tttataagta taccaccaat tgaaaggttt
    21901 tcatagttaa gaaattttaa agtcaaaagt tgcagataaa agcaaataaa caagaaaaca
    21961 aaaagtgaat caatcgcggt tattcaactt tttcttcgat tcgaagacaa tagaagacaa
    22021 tgaattttat atttcattgc attatccttg tgttattaga aaaagcatga tatattaaat
    22081 gagtaatcta ttttgaaacg taatttgagc gatatatcta catagataaa actccttttg
    22141 cctatcaaat atttattgca acgaaaaaac gtacattgat acgtatcagg aggaatttat
    22201 ttatgaataa cggtacagta aaatggttca acgcagacaa aggttttggc tttatcactg
    22261 gtgaagatgg aaatgatgta tttgcacatt tttcagctat ccaaggtgac ggcttcaaaa
    22321 ctttagaaga aggccaagca gtgtcttacg atgttgaaga tggtcaacgt ggccctcaag
    22381 caacaaacat tgttaaagct taataaaaat tgacttttaa ccgtcttttc gaaagaaaag
    22441 acggtttttt tgtacgaaaa aatt
//
LOCUS       DAXLPQ010000042        22194 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.042, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000042 DAXLPQ010000000
VERSION     DAXLPQ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.042"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            367..921
                     /locus_tag="ACF3UO_001934"
     CDS             367..921
                     /locus_tag="ACF3UO_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3657929.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1094..1531)
                     /locus_tag="ACF3UO_001935"
     CDS             complement(1094..1531)
                     /locus_tag="ACF3UO_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3657930.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1579..2526
                     /locus_tag="ACF3UO_001936"
                     /pseudo
     CDS             1579..2526
                     /locus_tag="ACF3UO_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            2797..3232
                     /locus_tag="ACF3UO_001937"
                     /pseudo
     CDS             2797..3232
                     /locus_tag="ACF3UO_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            3248..4081
                     /locus_tag="ACF3UO_001938"
     CDS             3248..4081
                     /locus_tag="ACF3UO_001938"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657931.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            4326..5351
                     /locus_tag="ACF3UO_001939"
     CDS             4326..5351
                     /locus_tag="ACF3UO_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657932.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5489..5614
                     /locus_tag="ACF3UO_001940"
     CDS             5489..5614
                     /locus_tag="ACF3UO_001940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657933.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            5639..6754
                     /locus_tag="ACF3UO_001941"
                     /pseudo
     CDS             5639..6754
                     /locus_tag="ACF3UO_001941"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            6837..7733
                     /locus_tag="ACF3UO_001942"
                     /pseudo
     CDS             6837..7733
                     /locus_tag="ACF3UO_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            7749..8573
                     /locus_tag="ACF3UO_001943"
     CDS             7749..8573
                     /locus_tag="ACF3UO_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657934.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8605..9915
                     /locus_tag="ACF3UO_001944"
     CDS             8605..9915
                     /locus_tag="ACF3UO_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HFD3657935.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10063..11322
                     /locus_tag="ACF3UO_001945"
     CDS             10063..11322
                     /locus_tag="ACF3UO_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3657936.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11332..12204
                     /locus_tag="ACF3UO_001946"
     CDS             11332..12204
                     /locus_tag="ACF3UO_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657937.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12216..13046
                     /locus_tag="ACF3UO_001947"
     CDS             12216..13046
                     /locus_tag="ACF3UO_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657938.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13086..15269
                     /locus_tag="ACF3UO_001948"
     CDS             13086..15269
                     /locus_tag="ACF3UO_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3657939.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15330..16550
                     /locus_tag="ACF3UO_001949"
     CDS             15330..16550
                     /locus_tag="ACF3UO_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFD3657940.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16547..18007
                     /gene="gtfA"
                     /locus_tag="ACF3UO_001950"
     CDS             16547..18007
                     /gene="gtfA"
                     /locus_tag="ACF3UO_001950"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFD3657941.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18084..19190
                     /locus_tag="ACF3UO_001951"
                     /pseudo
     CDS             18084..19190
                     /locus_tag="ACF3UO_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19512..19721
                     /locus_tag="ACF3UO_001952"
     CDS             19512..19721
                     /locus_tag="ACF3UO_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFD3657942.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19714..19863
                     /locus_tag="ACF3UO_001953"
     CDS             19714..19863
                     /locus_tag="ACF3UO_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFD3657943.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            20017..20682
                     /locus_tag="ACF3UO_001954"
     CDS             20017..20682
                     /locus_tag="ACF3UO_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3657944.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20966..22051)
                     /gene="xerS"
                     /locus_tag="ACF3UO_001955"
     CDS             complement(20966..22051)
                     /gene="xerS"
                     /locus_tag="ACF3UO_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFD3657945.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         7552 a         3331 c         4254 g         7057 t
ORIGIN      
        1 atgaaaagtt tggtagcacg gttattcata tgctaattta tttcacttta tagtaagggg
       61 agttcttagt atattgttca aacttaaatt tcatataatt taattatgta aattagctat
      121 tctaagaact tctacggata actgcccgtc taaaatttaa ataagagctt agaatcttca
      181 tataagtaag gttaattttt ttgtacaaaa aagtcggaat attctgagtt actgaaatga
      241 tataaaatca taaactaaat cccttgattt tattgacttt caaaagttta tatatataag
      301 ttaatgatta tggtaaaata tatacataat cattaactca gaatattttt aagaagggaa
      361 acaatagtga gctataatgt acaaccgtta aggacaaatg aagagataca agattttcag
      421 ttttggctaa gaagaacaag taatccggaa agagatagtt ttttattttt gtttggaatc
      481 aataatgggt tacgtatgtc agatattata ggattaaaag ttggagatat acgaggcaaa
      541 agtaagccta ttattgttga acataaaaca ggtaagcgaa aaccgatttt tatagataat
      601 ttgagagaag aaattttatt atatactgaa ggtaaagaag aaaatgattg gttatttccg
      661 agtcggcaac aaggtcgaca tataacaagg gatcgtgtct atcagatata tgcagatata
      721 gcagaaaaat taggacgaga tgatatagga acacatacat taagaaaaac ttttgggtat
      781 cactactaca agaaaactag agacattgct accttaatgt ttatttttaa tcatagctcg
      841 caagcaatta caaaaaggta cattggtata actgaagatg aaataggagc atcacttcgt
      901 ggatttaaac taggtgtata atttaaaaat ttttataaac agtaaagaca aagattaaaa
      961 gctattttta tctagaacga ttttatttca taaagttcgc ggaataaaag ctggggttac
     1021 tggtacttgg tataggttcg tgttatataa actaagtaat taaataacat ttttaggttg
     1081 gaaaaggatg aaattaaaaa aagagaatca atacggtctc aaaaacgcaa acgctgcgga
     1141 ataagaaaaa tactgataac tcaacgttta gcagactatc taatagggat agtctgcttt
     1201 tttcgttttt gaccatactt ttgaccttct gcaaacttcc ttgcttttcc tctgtagaac
     1261 tcatgaaatc tgcaaaacga attgccgttt cctctgtctg ctttttcgcg atatgggtgt
     1321 atatatcatc catagtggtt ttaatatctg tatgtccaag tcgaacatac acttctttga
     1381 cagacgcacc agattcaaag agcagactac aatgggtatg acgaaaacca tgaagtgtga
     1441 tatgttttaa gttattctct ttaatgatga ttttcaaatt gtgatttaca tagtctaaat
     1501 aaaggggctt attttcttct gatgaaaaca aaagttgttc accatctttt ataggtttga
     1561 ttctcatttt tagatattat gcccgcacgt attcatcaca tttctattgt gaatcgcttt
     1621 attcgaccga catttgactt ttatcataat atactcggtt taaaattact aatgaaaaca
     1681 attaatcaag acgatcatac catgtatcac ctgttttttt cagataatca ccaccgtgtg
     1741 ggaactgaac tgactttttt tgaagtacaa gaagggaaca accagttttt tggaaccaat
     1801 acgattgaac gaacgatact aaaagttcct tccgaagcat cattgcattt ttgggaaata
     1861 tattttgaaa cacaaggcgt ttgccattat ggaatcgaat cattttctgg acgacctatc
     1921 ttacgttttg aagggccaga tgcaacacga ttagctttag ttcccttacg cgaatttgaa
     1981 gatattgatg attatttccc gtatgtcaca gaccagatcc ctacagagca tgccatttta
     2041 ggaattgatg ccattcaact acgcgtacaa tattccgatg cgactgaacg agagttattg
     2101 tcggtaggct ggtagcacaa agaatacgtc agtttctttt cgggtcatca acgagtgaca
     2161 atcttagaaa atcaagacac tcagttctat caagaagttc agattattca agatcgtgag
     2221 aatccagttg ccattgaagg gattggtagc gtccatcatg ttgcgtttgg cgtagaaaat
     2281 aaatctgatt tacaacgcat cgacaaacaa ttacaagagc gcaattttat aaattcagga
     2341 ataaaagatc gtgaattttt tgtatcactt tattatcgtg acccaaatca attattgatt
     2401 gaaattgcta caggggaagg aaacctagat gcaaaagcgt atgaaaatca aagtccacgc
     2461 tttgaagaaa ttcctttatt tttaccgcag tacttaaatt tcattcgtga acaagtggag
     2521 caataattag ctaatcaaat ccatgacgaa gagtaagagg ttgactcata agtcaaaaaa
     2581 taaagaaaaa cgcatcaaat ccattctaaa gaatgttgat ttgatgcggt tcctattttt
     2641 ataaactatc attttcgact aataaaacta cttatgagtc agcctctctt tttttcttga
     2701 tttttatacc tctttctagg taaactaaac atctgccaaa aataccgtgt ctcattgaaa
     2761 cattctcaac tatttcaaaa taaaggggag taccaaatga acgagtatat tgaaattatc
     2821 cacgcaagag aaacaactta aaaatgtcag tctcaaaatt cccaaaaata aaattagtat
     2881 ttttaccagc gtatctggtt caggaaaatc atcgattgtt tttgatacta ttacccaaga
     2941 agctggtcgt caactgaatg acacctatga tagttttacc cgtttatttt tacctaaata
     3001 cagtcgtcca gaggttgatg agattgataa tctttctacg gcgattgtgg tcaatcaaaa
     3061 gaagattggt ggcagtgcgc gctcaacgtt agggacgatt actaacatca atgcgttatt
     3121 tcgtgtgttg ttttcatgtt ttgcaacacc tagtttagga tatgcaaatg cttattcatt
     3181 taatgatcct agtggaatgt gttctgtctg tcagggaatc ggtaagacga ttgcattttt
     3241 aataggattg ctttattttt cggctattga taatgctgat tttgtatttt ctgatccatt
     3301 taccgcagaa gttttgtctg gaattgagga acaggcaaag aatcatggtt attttgtatt
     3361 ggtgcataat gttaattcag cagaagatgt taaaactatt cagagaaatt ggcgttttga
     3421 ggggttcatt gttgttggtg tacgtgtaaa agaatttttg gaattaaata acgtttttga
     3481 tggtcctgtt gtttatattg atacgcatct ttcaaaagag acattaagag aacttgaaca
     3541 acaaatgaat cgtttatttg taaatacaaa tgattaccaa gctagtacat tggcagtgga
     3601 acatttgatt cattatggtc atgagaaaat agcgtttctt tcttttgact acattgtagg
     3661 tgaaccaagt gttattcaag aacgacatca agcttatatc gatacattaa agaaatatca
     3721 tttaaccttt aaatcgcatt ggatatataa caactctgaa tttgagcgaa tttatcaaga
     3781 attagctgaa tttactgcaa ttgttgttac tggagattat ttagcggcta aattagtaaa
     3841 atttttaaaa aataagaata aacgagtgat ggaacaatta tcgattattg gatttgatga
     3901 tattactttt gcagaattaa tggatcctgc gttgacaaca atacgactaa atccaggtaa
     3961 caagggggcg attgcttttc accaactgat tggactggcc aaacaagaag aaataaaaaa
     4021 tcaagtacta ctattagagg gagaattgat ttctcgagac tctgttcaca aaatcaaata
     4081 aaaaagctct gtgaaataag tatagttaac aataaaatat ccgaacgata gagagaatga
     4141 actgtgatct agcagttcct cgtcgcaaat tcactagaat tagcattatt tactctaaat
     4201 tgttcggata ttttttcttg tttttaatta tgattacagt gcctattttt aacgaaattt
     4261 gcttattttc aaaatgtatg attatatgtt agtaaacact ttcaaatatg aaaagaggag
     4321 ctattatggt aggaattagg gatgttgcaa aacgggcggg tgtgtccatt gcaacagtat
     4381 cgcgcgtgct aaatgaggat ccgacacttt cagtaaccga tgaaaccaaa cgaaagattg
     4441 cagaatcggt taatttttat cattatgtca aaaaaagtcc cgttgcaaaa aatttaacaa
     4501 atattgcatt aataacgaca gtttctgaag tagatgagtt ggaagatccc tattttcgaa
     4561 cgattcgcag agggattcaa gtcgaagcag aacaaagcaa agtcaatttg aagaaaatta
     4621 ttcgtttgtc agaaacaccg ttggagcaag acgatttgct aaaatgtcaa ggtgtgttga
     4681 ttattgggca ggtgctatct tctgtgattg aagaagtatc agcaattaat tcgaatgtcg
     4741 tagtgattga tgaccctagt attgaagctg aagtagatgc agtttatact gatttaacaa
     4801 aagcaacgaa tcagcattta gatcgattgt ataaaaaagg acaccgaaac attgcgttta
     4861 tcggaggagg acgtgttcgt ttagatagcc aaggaaataa acacgtgtca gatgatgatt
     4921 atcgaaaaat agcctatgag acgtggatga aacaaaaagg attagaaaaa tatagtcaaa
     4981 tttatttaga aggctggacc acacttgacg gaatgcaggc agcagattta cttttgaaaa
     5041 aacatgctaa agataagttg ccgactgcta tcatggtagg aaatgatcct attgctgtgg
     5101 gggtttatcg ttcacttcaa aaaaatggtc tacatattcc agaagatatt tcgattgtga
     5161 gttttgataa tattgaagtt gctgaatttt taacacctgc attaaatacg gtgaatgtga
     5221 atacagaaga aattggaaaa ctagcagttc gcatggttaa tgaacgaata aaagaagtta
     5281 gaaatgtttc gatcaaagtg attgtttcta ataatattat tgttagagaa agtgaaaaaa
     5341 atatcgatta aaaaagtaaa catccaaaaa agggtgttta cttttttgtt tactaatatt
     5401 tttagtaaaa aatctcgaca aaacattaag taaacagtta tggtgttgtt aacaaaaaga
     5461 aaacgcattc aaaacaggag gaattaagat gaaacatttc aaaaaaatag ctttaacagg
     5521 gatagctgtt ttaactggga cattactcgc agcatgtggt gggggagata gtaattctaa
     5581 agacgggcaa gtaactttaa gctatgcgag ttgagatact gaccaagctc caggactaag
     5641 aaaaatgtta gatgaatttg aaaaacaaaa tcctgatatc aaagtagaaa tggagacaac
     5701 gccttgggat caatattggg ttaaattaga agctgcaaca acgggaggta atatgccaga
     5761 tgtagtaacc atgcactcta gcgaatccta taaatatatg tcacagaatg ctttgatggg
     5821 acttgatgat gttatcaaag aaaatgatat tgacatggga aactttactg aaggaattgc
     5881 tgatttctat acgcttgaag acgaactata cgcaatccct aaagatgctt ctgtagtggg
     5941 gctatggtac aacaaagaat tatttgataa tgcaggtgtc gattatccag atgaaacatg
     6001 gacatgggaa acactcagac aagctgcaat tgatttaaca gatgaatcaa aaggcatcta
     6061 tggttttgca tcacatattg gaacagagac tggctactgg ccatttattt atcaaaatgg
     6121 gggagaagta tttgccgatg acaatacaaa atcaggtttg aataccccag aagcacaaga
     6181 agctttagct ttttatcgag atattgcact tgttgatcat gcttcaccaa caattacaga
     6241 attacaagat cctgataagt taagtcgttt tcaatcaggt agattagcaa tgatgattga
     6301 aggaaactgg tttgcaccgg gatttttgaa aaatgactat ctagttgaaa atgttgcttc
     6361 tgccgtgtta cctaagggaa aagttaatgc aacaattaca aatggacttg gttgggctgc
     6421 cagtgcgagt acaaaatacc cagaagaagt gaaaaaacta atggcatttt tagctagtga
     6481 ggacgccaat aaaatccaag cggaaacggg ggcatcaatc ccagcactaa aaggctttga
     6541 agacgagtgg gctgcttctt cagatacaat tgatttgagt gcttttggaa aaatgttgga
     6601 gtatggagtc cctcgtccat acaataaaga tggattacga gctgaacaag cagaagttca
     6661 aattattaac cgtattctgt ctggtgaagt aactgttgaa gatggaaccg ctcaaattga
     6721 aaaagaagtc aatgcgatat tgagcggaaa ttaaattagt taattataca atatacaggc
     6781 gaaaggattc tatttcgtct gtatattaat ggatgaatac caaaaagggg gatattatga
     6841 aaaatcgaat ttttggaaaa tatcgtaaag atcaagtgat atggggctat atttttattt
     6901 ttccaacggc attaggatta attttattaa atatatggcc agcaattcaa acagcaattt
     6961 taagttttca aaaaacggta gggttcggtg atactgaatg ggtcggatta agaaattacc
     7021 aaaaaatgtt tgcagacggt gaagtttttc agtctttatt aaacacatta atttatgcag
     7081 tggtttcgat acctagtatt gttgtattat ccttgttggt ggcagtttta atgaatagaa
     7141 aagttaaagg attgtcgatt tatcggacaa tttattttct accagtcgtt gctgcaccat
     7201 ccgcagtcgc aatgatttgg cgctggatgt tcaataatga ttatggactg attaataaca
     7261 tgttggctaa aataggtctc gatggaccag catggttaac ggatccatcg attgcgattt
     7321 attctattat cattgtagga gtttggagtg ctattggtta taacatggtg ttattactag
     7381 ccggcttata agaaattcct aaagattatt atgaagcagc ggaaattgat ggtgctagtc
     7441 caatccagca gtttttcaac attacgttac cattagttac accaacatta ttttttgtag
     7501 ttgtaacaac agttatcaat gctttccaag tatttgatgt tatttttatg atgattactc
     7561 ctaatagtac cgccatgttt aaatcacaat cattagccta tttattctat aaacattcat
     7621 ttattttaaa tgacaaggga tatggttcgg caatcgttat gttcctttta gtgattatat
     7681 taattattac tgcaattcaa atgaagttgc agaaaaagtg ggtaaactat taaggaggct
     7741 atcaaattat gaaaaataaa tttttttcaa atgcgccaat ccatatcatg cttattttag
     7801 gtggtattgc aatggcatta ccttttattt ggatgatttt aacttcaggg aaaacgttgg
     7861 ttgaatctac ccaaattcca cctacaattt tccctgagaa atttcagcta agtaactatc
     7921 aacaagtact tgatttatta ccattcatgg ctttttatat caatacattt ttaatggttg
     7981 ttggacgagt gattggctcg gttttatttt cagcaatggc tgcatatgct tgtgcgcgtc
     8041 taagttttcc agggaaaaat atccttttca gcttagtact tattcaaatg atgattcccg
     8101 gttccatttt tattactcca cagtatttat tagcacaaaa attgggtatt ttaaatacaa
     8161 ttccagcatt aatattacca ggggtagtta gtgcgtttgg tacgttttta ttaagacaat
     8221 ttttcttagg tttacctgat gaattggagg aagcggccta tttagaaggt gccaatattt
     8281 ggacgatctt tttcaaaatt atgttgccgc ttgctaaatc aggattggtt gcacttggaa
     8341 tattcacagc gttgtttgca tttaaagatt taatgtggcc attgattgtc aatacttcaa
     8401 ttgataagat gcctttagct ccgggattag caaacttaca aggacaatat gccacgaact
     8461 tcccacaatt aatggcaggt tcgttattag caatttggcc aatagttgtg atattcatcg
     8521 ttttccaaag aaaattcatt gaaggaattg ctacaacagg tagtaaatta taaaactatt
     8581 aattagtgat tggagagtaa gtacatgaca aaaattacat ttattggtgc aggaagtact
     8641 atttttgcaa aaaacgtatt aggcgatgcg atgttaactc caagtctaca agatgcacat
     8701 attgcattgt acgatattga tgaaaaacga ctaaaagaat caaatttaat gcttaaaaat
     8761 attaataaaa attcgaatga aaatcgtgct gatattgttt cttattatga tcgcaaagaa
     8821 gcgttaagag aggctgattt tgttatcaat gctattcaag tgggtggtta taaaccttca
     8881 acagtgattg attttgatat tcctaaaaaa tatgggttgc gacaaactat tggtgacacc
     8941 atggggattg gtgggatttt tagaacccta cggacactac cagtaatgtt agactttgct
     9001 aaagaaatgg aagaagtttg tccaaatgct tggttattga actatacaaa tccgatggcg
     9061 atgttaacca tgggtgtttt aaaagcgacg agtattaaga ctgttggttt atgtcatagc
     9121 gttcaagtat gcgtaccaga attgtttgag catttaggaa tagccgatca atatgactta
     9181 aatgactttc aatggaaaat tgcaggcatt aatcatatgg cattcttgtt ggaaattaca
     9241 aaaaatgggg aagatttcta tccaacaatt cgtcagttag ctgcagaaaa accaaatcca
     9301 catccagatt ctgtacgttt tgaattgttg aaacgttttg gttactatat tacagaatca
     9361 agtgaacaca atgcagaata ccatccatac tttattaaat caaaataccc agaattgatt
     9421 gacgaattag ggattccgtt ggatgaatac ttacgtcgtt gtgaacaaca aattaatgat
     9481 tgggaaagca tgcgagagga cattgtaaat aatggggagt taacacatac gagaagccgt
     9541 gaatatgctt catatatcat ggattctatt acgacaggaa ctccgtcagt gattgcagga
     9601 aatgtcttaa ataaaggctt aatcacaaac ttaccgacag atgtttgtgt ggaagtacct
     9661 tgtttagtcg ataaaaatgg cgtgcaacca acctatgtcg gtgaattgcc aacacaatta
     9721 gctgctttaa atcggacgaa tatcaatgtt caagaactga cagtagaagc cgctttaaca
     9781 ctagataaat caaaaattta tcaagcagcg tatttagatc cacatctatc atctgaattg
     9841 tctttaacag atatcaaaaa tttagtggat gatttaatcg aagcacatgg ggactattta
     9901 cctgaatata attaaaaaga agctgaaaga gtaaggaatt ttcaattcct tactcttttc
     9961 ttagttaaat ttagtaaaaa tattgacaaa acacttagta aacagttaca ttagtgttaa
    10021 caaaaagaaa acgcattcaa attgtataag gaggagcata aaatgaagtg gtctaaaaaa
    10081 attattttag cttgtatagc actaggagca acgatctctt tgactgcttg tggaaaaaat
    10141 caggaagatg caagcggtaa ggtagaaata gagtttttta atcaaaaaaa agaaatgact
    10201 caaacgattc aggagattgc taaagatttt gaagcaaaaa accctgatat tcatgtaaaa
    10261 gttgtggatg taccgaatgc tggtgaagta attaaaacac gtatgcttgc aggcgatgta
    10321 ccagatgtca ttaatcttta tcctcaaagt atagaattga aagaatgggc gaaagctggt
    10381 tatttagagg acttaaccga agaaccgtat ttagagaata tcaaaaatgg atatgcacaa
    10441 cgttttgcta ttgaggatcg tgtatatagc ataccattaa ccgctaatgt ctatggtttt
    10501 tactataaca aaactgcttt tgaggaaatg gggattcaag caccagaaac ttgggcagaa
    10561 tttgaaaaaa tagtagctga gattaaagat caaaacaaag taccgtttgc gattgcagga
    10621 gcagaaggct ggactttaaa tggttatcac caactagcta tagcgactgc tgctggtggt
    10681 gaagaggaag cgaacaatgt ttggcgtttc tcagaagtta atggaattaa tgctgaaagc
    10741 aaagaaatgc aaaaagattt taatcgatta gatttgttaa gagaaccaaa agctttgcaa
    10801 aacaactggc aaggtgccgg ttataacgat acagtagtta cttttacaaa aggtgatgcg
    10861 ttgattatgc cgaatggttc atgggcaatg ccgatgattc attcacaaaa tccagatttt
    10921 gaagtaggaa cttttccttt tccagcagat gaagcaggtc aaagtctaac gattggcgca
    10981 ggagacctag ccttatcagt ttctgcaact tctcaacata aagaagaagc caaacgtttt
    11041 gtagaatata tgacaacacc tgaagcgatg cagaaatatt atgatgtaga tggtgcaccg
    11101 tgtgctgttg agggcgttat cgagaatact caggattcac cattaagtgg tttaactgaa
    11161 cttgctttta ctgatcgtca tttagtttgg ttagccaaag attggaatag tgaaaatgat
    11221 ttttatacct taacaacaaa ttatttacac aatggcaatc aaaaagccat gattaacgca
    11281 ttaaatgctt tctttaatcc aatgaaagct gacggaaggt aggaaaataa aatgaaaata
    11341 aaagaaattt taaatcgtta ctgggcaatc atttttgtag caattccaat tattttgcag
    11401 atgatttttt tctactttcc aatggttcaa ggtgcttttt acagtttaac taattggact
    11461 ggtctgactt ataattttga ttttgtgggt ttgaacaatt ataagattct tttttctgat
    11521 ccgaagttta tcaaatcgat tggcttcact ttaattgtga cgctttgcat gattgctgga
    11581 caaattggtt ttggtatttt gattgcgcgg gcgttgaacg caaatattaa agggaaaaca
    11641 ttctttagag catggttctt ttttccagcg gtcttatcgg gcgtggttgt ttctttagta
    11701 tttaaacaaa tttttaacta tggtttacca aaaattggta gtatgttagg cattgaattt
    11761 ttacaaacca gtcttttagg aacaacatgg ggagcgattt ttgcagtaat ttttgtttta
    11821 ctttggcaag gaattgccat gccagtcatc attttcttag cgggttttca aagtattcca
    11881 caagaaatta ttgaagctgc tagaatggat ggggcgaatg ataagcaaat tttttggaat
    11941 attgaaatca cctacttatt accaagtatt tcaatggtat ttattatggc attaaaaggt
    12001 ggcttaacag catttgatca aatttttgct ttaactggtg gtggaccaag cgatgccaca
    12061 acatctttgg ggttacttgt ttataattat gcttttaaaa acaatcagtt tggttatgcg
    12121 aatgctattg ctttagtctt atttatctta attgggattg tttcactggc acaattaaaa
    12181 ttatcgaaaa aatttgaaat ctaggaggtt tcccaatgaa aacatcaaaa gaaaaaaata
    12241 tttctaaata cttgctttta ttattagggg gcttcatgat tttagttccc ttagtttcaa
    12301 cgctattcgg ttcatttaaa acaacacccg atattatgaa taatttcttt cgttttccta
    12361 atccagcgac tttggaaaat ttccgaagat tgttagcgga tggaattggt cattactttt
    12421 ggaattcggc aatcatcaca atcattgcag tagttgctgt gacagcaatt attcctatgg
    12481 ctgcttattc actagcaaga aaaatgactc gtgggaaagc atacggattg atgtatttat
    12541 ttttaatttt aggaattttt gttcctttcc aagtaattat gattccgatt accgttatga
    12601 tgagtaaaat tggtttagca aatatgtggg gattaatctt actctatctc acttatgccg
    12661 taccacagac actattttta tatgttggtt ttattaaact aaatgtgcct atcagtctgg
    12721 atgaggctgc tgaaattgat ggggctagtc actttacaac ttatttcaaa attgttttcc
    12781 caatgttaaa accaatgcat gcgacgacta ttattcttaa tgctctatgg ttttggaatg
    12841 atttcatgct accattatta attttaaatc gtgattctaa tatgtggaca ctaccattgt
    12901 ttcaatataa ttatacggga caatatttta acgactatgg tccaagtttt gcttcctata
    12961 cagtaggaat tgtcacgatt acactagttt atcttgcttt ccaaagaagt attatagctg
    13021 gaatgagcaa tggagcagtg aaataaccaa taaattattc tcattataaa ggagttcata
    13081 aacttatgat tatatttgac aatcacacac aaacatttca tttacaaaat aaaaaaatta
    13141 gctatctatt aggaatcgaa gaaaataatt atttaacgca tctttatttt ggaaaaaaga
    13201 ttacgcacta ttctggtggg tatcgctacc cccgaacaga tcgttccttc tcacccaaca
    13261 atgcaaatgc gcaagatcgt ttattatctt tagacacatt accattagaa tttccaggat
    13321 atggacatgg tgattttaga gaaccggcgc ataatattaa attaggaaac ggtagtcgtg
    13381 taaatgattt tcgttatgat agctacgaaa ttcaaaaagg aaagcccagc ttagcgggat
    13441 tgccagcctt atatacggaa gatgatgatg aagctgaaac gctgattatt caattgaaag
    13501 acgcgattag tggattgact ttacagttgt tctacacaat ttatcaaaat cacagtgtaa
    13561 ttattcgttc tacgcaatta gtaaataata gtgatgaaac agtggagatt aaccgcttag
    13621 ctagtcaatc aattgatttt ccaaatcgtc cactcgagtt aattcattta aatggtacct
    13681 gggcaagaga acgtcaaatg actagagaaa aaattcatac agggataaaa gtattagata
    13741 gtaaacgcgg atcaagcagc catcaacaaa atccgtttgt tgctttagta gatgccaaaa
    13801 cagatgaatt tcaaggagag gcatatggat ttaatttagt ttatagcggt aatcacgaaa
    13861 cggtgattca aaaagatcca tttgaccaaa cacgggtcat tatgggaatt aattcattta
    13921 attttggttg gcaactaaaa actggcgact catttcaaac gccagaagtc gtgatggttt
    13981 atagtaatga aggtctgaat acgttatcac agacgtatca tgaattgtat aatcaccgtt
    14041 taattcgtgg aaactatcgt ttaaaagaac gtcccacgtt aatcaacaac tgggaagcaa
    14101 cgtattttga ttttaacgaa gaaaaaatca tgaatattgt cgatgatgcg aagaacttgg
    14161 gcattgaaat gtttgtttta gatgatggtt ggtttggcgg tcgtgaaaat gacttcactt
    14221 cattaggtga ttgggttgaa acagaaggca aacttgcttg tggtttggaa aatttagcca
    14281 agcaagtgca tgataacggg atgaaatttg ggatttggtt tgaaccggaa atgatttctg
    14341 aagatagtga actatttcga gcacatccag attgggcatt gggtattcca ggtcgtgacc
    14401 gctcaattag tcgaaatcaa tatgttcttg atttttcaag acaagatgtt cgtgataata
    14461 tctatcaaca aatgacggcg atttttgatc gtgtaccgat tgattatgtg aagtgggata
    14521 tgaatcgaaa tatgacagaa gtctattctg tcttgttgga ctcaacgatg caaggtgaag
    14581 tggctcatcg ttatatgtta gggttatatg aatttttaga aaagttaaca acgaattatc
    14641 caactatttt atttgaaagt tgttcgggtg gaggcggtcg ttttgatgca ggtttcttgt
    14701 attacatgcc acaaacttgg acgagcgaca ataccgatgc cgtggctcgt ctgaaaattc
    14761 aatatggaac cagcttagtg tatccaattt caagtatggg tgcgcatgtt tcagcagtcc
    14821 caaatcatca aacaggaaga gaaacgagtt taactattcg tggcaatgct gcgatggctg
    14881 gtgtttttgg ttatgagcta gatctaacgc aattaacttc tgaagaaaaa gcagaaatta
    14941 aagaacaagt tgccttttat aaaaagcatc gccaactttt gcaatatgga actttttatc
    15001 gcttggaaag tccgtttgaa ggcaatgata ctgcatggat gtttgtctca aaagaccaaa
    15061 cagaagccat ggtcttttat ttccgagtat tagcagaagc tgcgcatcca ttagtcacat
    15121 tgaaattagc aggattagca gaagaagcaa cttatcaaat ggaagatgta acatttgctg
    15181 gcgatgaatt gatgaatctc ggtttttata ttgactcaga actacatggt gattatgcga
    15241 cacaacgctt ttatttgaaa cagatatagt agcttgaatt tacaatataa gtgcaacacc
    15301 aaaagagact cattccaaac gaagaaaata tgttttattt acacgcattt actaaaaagc
    15361 agcctgattt gaattgggaa aatgaagaag tacgtgaaga aatctatgca atgattaact
    15421 attggttaga taaaggacta ggcggattta gaatcgatgc gatattaaac atcaaaaaaa
    15481 aactagagta tggcatcttt gaatctgatg gagaagatgg gttagccttc attgggccct
    15541 ggattcttaa tcagtcgggc attgaagtgt ggttaaaaga aatgagagag cggacattta
    15601 aaccacataa tagtatgacg gtagcagaag ccgatgttcc taatgaacgt ttagatgaat
    15661 atattggtga agatggctat tattcgatgg tttttgattt tagttatacg gatattgatg
    15721 tacctgaaac tggtgaatgg tttaaagata gccaatggac atggacggat atgcgtacca
    15781 atatttttac gaatcaatta gttacgcaag ataaaggttg gggcgcctta tatttagaaa
    15841 accacgatca accacgttca attaataaat atattccaga agaatggatc aatgattata
    15901 gtaaaaaaat gttggcgacg ctttttatgt tactaagagg tacccctttt atttatcaag
    15961 gacaagaact aggaatgacc aacatagaaa tggcatcatt agaagatttt gatgatgtag
    16021 ctacgcattc tcagtataaa cgggcattag aatatggatt ggcaccagag caagcattga
    16081 aagctgtcaa taaacgaagt cgggataatt ctcgcacacc tatgcaatgg aatacgcaaa
    16141 aaaatgccag attctcaact tctgataatg tatggttaaa agtaaatcct aattatccag
    16201 aactcaatgc agaagctcag ttaaccaatc aacagtcggt attcaattat tatcatcaat
    16261 taattaaatt aagaaaaaat agtgtataca aagacgtgct aatctacgga caatttctac
    16321 cagtgaaaga taaaaatgaa catattttgc tttatgaacg ccaattagaa gataaaatcg
    16381 tattagttat cttaaacgtt acagcaacag aacaagaata ttatgtagat gaacagtacc
    16441 aacaagtatt aatcaataat tatgaagatg ttttattaga tcaaagtcga aaattgcgtt
    16501 tacgaccgtt tgaaagtatt gtattagcta attatggagg acaattatga aaattaaaaa
    16561 cgaagcaatg ctcatcacct atgcagatag tttaggaaaa aacatgggcg aattaaaaca
    16621 agtcttagac aaacatttac aaggtgttat tggtggtgta catctgttgc ctttttttcc
    16681 atcgacaggt gatcgaggct ttgcgccgag tgattatacg acagttgatc cagctcttgg
    16741 aacatgggaa gatgtggaag cattaggtga agattattat ttgatgtttg attttatgat
    16801 taatcacatt tctcgtgaat caaaattttt ccaagatttc aaaaaaaacc atgagcagtc
    16861 accatacaaa gaaatgttta tccgtattca tgaatttttc ccagaaaatc gaccaacaca
    16921 agaagatatt gatttaatct acaagcgtaa agacaaagcg ccgtttcaaa cggtagaatt
    16981 tgcggatggt acgacagaag aggtttggaa tacctttggg gaagaacaaa ttgatttaga
    17041 tgtgaccaaa gaagttgtga aagaatttat tcgagaaacc atcaaagata tggcgaacca
    17101 tggctgttct ttaattcgat tagatgcgtt tgcttatgcg attaaaaaat tagataccaa
    17161 tgatttcttc gtggaaccag atatttggga acttttagac gaagtgcgtc aagaagcagc
    17221 gaaatatgac gtcgaattat taccagaaat ccatgagcat tattccattc aaatgaaaat
    17281 tgccaatcat gattattata tctatgactt cgccttgcca atggtcactc tgtattcact
    17341 ttatagtgga aaatcagaac gtttagccaa ttggttgaaa atgagtccga tgaagcagtt
    17401 tacaacattg gatacgcatg atggaattgg tgttgtggac gctcgtgatt tattaacaga
    17461 tgaagaattg gattacacct ctgaggaatt gtataaagtc ggggcgaatg tgaagaaggt
    17521 ctattcaagt gccaattaca ataatttaga tatttatcaa attaacagca cctattatag
    17581 tgcattaggc gataatgacc gtagctatct gttagcacgt gcgattcaag tatttgcgcc
    17641 agggattcca caaatttatt acgttgggtt attagcagga aaaaatgata ttgaactgtt
    17701 ggaagcaacg aaagaagggc gtaatattaa tcgtcattac tatgatttag ccgaaattga
    17761 agaagaagtg caacggccag tgattcaaca attatttgca cttttaaaat ttagaaatga
    17821 atctgcggcg tttgatttgg atggaacgat tgaagtagca acgccatcag aatcagaaat
    17881 agtgattaca cgtaaaaata aaaacggtag tgatagtgca acattaacgg ctaacttgga
    17941 tacgaaagaa tttatcattg agtctaaaga tataaaaatt ttcactagtg ttgcattaaa
    18001 attttaacct attccataga acaaaaaatc ctttatacta gcacttggat gacttatcca
    18061 agaccaataa aaaggactca tacatggata agtataaaac aaatacagca tttaataaat
    18121 ggttttctgc cataaaatta ggaaaacttt ctgtcaactc ccaaaaatgt atttttgatt
    18181 acaattcgta tcgtaaaaaa ctgtcttttg aagctgtgct caagctcttt ctctacgcag
    18241 ttaatgaaga aaaagaaagt ttgcgtgatt tgagtacagc tcttatcgac cgatcgctcc
    18301 aactagaaac cgatgtgtca tcgattagtc atacccaatt gtctcgagca tttaatgcac
    18361 ttgaacctaa agtgttagaa gaaatttttc aacaactgtt agaaaaagtt caacatcaaa
    18421 tcaaaccaac caagcgaaat catctgtatc tgattgattc cagtacgttt tcgcttagtt
    18481 taaaacgtca taagtgggcg actttccgtc aaacaaaatc aggtgtcaag ttacacttaa
    18541 actattgtta tatggacgat actacgatgt atccaactga ttttacctta acaaatgccc
    18601 atgaacatga tctcaatcaa ctaccagtat tggtgaatca accagaggca acttacgtgt
    18661 ttgatcgtgg gtattaggac tttgaaaaga tggatcagat gcattgggat ggctatttct
    18721 tcgtcactcg gattaaaaaa aacaccaaag ttcacgtgat agatactctg gaaacatcgc
    18781 cagaaacaga aattctacga gacgagctgg ttcgtttagg atctaaaacc tatctaaccg
    18841 ccaatttccg actagtcact gttcaagata agaacggacg tgtgtttcaa tttatcacca
    18901 atcgaatgga cgtctcttca aaagaaatct ctgatatgta tcacgctcgt tggcaaatcg
    18961 aattgttttt caagcacatc aaacaacaca tgaccattaa aaccttcttt tctcaaagtg
    19021 aaaaaggcgt gcagaatcaa ttgattttaa cgatgatttc cgctctcctc acgtttctca
    19081 tcaaattgga gacgaaaacg gaaaaatcag tgttccaaat caaacgattc tttcgttatt
    19141 tactgtttca gccctttgaa tgttgtctag aaaaattaat tcccacatga gaaaaaagaa
    19201 atttggctcg ttacttttgg ttttcagttg aataacagat aaaaaatttt ctggaaaaag
    19261 tcatcctctg cgtcagcaca gttttttttg acttattttc agaggaaata gttttcagaa
    19321 tattctaaaa tgttttatgc aacactagtg atatttttta gaattagatt tctaatgtgc
    19381 attttttgag tattaaggag caagtataca aagatttata aagctgatta aatttgaata
    19441 aaaatatgca ggaacgctac tatttttagt agtgttcttt tttatatttg aataaaaaat
    19501 gtggtggtta aatggtggtt ataacaaaaa atgaattaat gaaattaggt tatgggaagt
    19561 atcagtctga gagaatcata cgacaggcaa aagcaattat ggtttcaaaa agctatacct
    19621 attacgaaaa tagaagatta ggactagtac ctgttgaatc tgtagaagaa gttttaggta
    19681 tgaagataga ggtagaggag gattttcaga atcatggtta attttaaaaa agataaaaat
    19741 gggaaatatc attttactgc tagtttggga ttcgacaaac gaacagggaa aagagtacaa
    19801 aaaaacgtag aggggttaaa acagttaaag aagaaaaaaa gcgtataccg aacttgtttc
    19861 taattatgga aaagaagcag aaacttctca aagtactatg ttgtttgagg agttttttta
    19921 taaattattc ctaccttatt atcaagggaa agtagaagaa agaacatata aaaatcggtt
    19981 atctacaatc aaaaaaactt ttcttatttc tttaaaatgg agttaagaga aatacgtcca
    20041 attgacattc aaaagtggca aaataattta ttgagcaaat ataaaaattc ttatgtaaga
    20101 aacatgtatg ggatttttca gatgtcatta gatcgagcag ttgttttggg actacttgaa
    20161 aaaaatcctg caaaagttat tggaaatgtg aagaaaagga aaactacagt tgatttttgg
    20221 acaaaagaag aatttacaaa agttatttca actttttata ttgatgattt gtaccaacat
    20281 tttggtttta tttgtatgtg gttacttttt atgaccgtta tgcgtttggg agaagccact
    20341 gcattaactt ggaaagatat tgattttgaa aataaaaact tgcgtgtgaa taaaacactc
    20401 tattataaga gagccaaaac ctatgagttt gtagaacccg aaacggcttc tagtattcgt
    20461 acaatcgaac tagacgacaa tacaattacc tttttaaaag cttggaagga gcgtcaagtt
    20521 tcaataggag gcatgtcgtt tgtactttct tataatggaa cacctactca gaaatataca
    20581 atccgtcata ttatgagaag acatgcaacg atcgttggtg ttcatataat ccgcatacac
    20641 ggattaaggc atagtcatgc ttctttgctt atatcacaat aaaaagatgc acttcgaatt
    20701 aaagaaaggt taaaacatgc tgatgtacaa acgactttag gaacttatgg tcatttgtat
    20761 ctaaattcat tgagagagat aacaaatgat cccacagatt atatccaaac taatttttct
    20821 aaaatcaaac cgacacctat ttacgataat aaaaaataaa tgataaacaa aagtaggatc
    20881 acaccaaaag aaacacacta gaaaaactat aatacaggct tttctagcgt gttgtttctt
    20941 atttccgcct atttatacat tatactcata aagcatttaa tgcatcgatc gtagccgcat
    21001 tgtctatatg ggtatataaa gttgttgtat tggtacttga atgtcccaat tgttgggcag
    21061 ttaataccaa tgaatttgtc tgttggtaga gtctagtagc taatgtatga cgcagtttgt
    21121 gagggctgac ttgaattcta aagccttttg aatattttgc taccatccgt tcgattgcaa
    21181 taccggatat acgcttggct tctccttggt aaattgctag aaataaagct ttttcgtttt
    21241 ctgttacttt atatcgttct ttccgaatag ctagataatt agctaaatat tccattgcga
    21301 atgctgctat attgacagca tctcttttat ttccttttct agttactacc acattattct
    21361 tatctaaaga taggtcatct aaattaatat ttataacctc ggagagtctc aatccagatc
    21421 ctaaaatcag tgcattgatc gccaggtctc tttctacatc tcgttgataa tagatcaaag
    21481 ctcgtttact caaagtattt ttatattcat tggcaatata atctagataa ttttgtgtat
    21541 ccttatctag aaataatttt ttctcaatgg cattggcacg tgcagctaac gtagttttat
    21601 ctgtgatggt tgctacttga tccataggat tattgtctaa gtatggtttt cctagaggat
    21661 tattggaact tttcgaaaga tatttaaata gaacctttaa tgccgtgata tttctattga
    21721 tagtagaagt agatagacct aagttattat tatctttgag cttagttttt gttgtctctt
    21781 tttttacatt ttcttttgtg cgacgtttca aatgagattt gtacaagttt aggtcatagg
    21841 cagttaactg tcttatcgag gtgatagaag tatcaggaac gatagactca ctcagaagcc
    21901 attcataaaa gagcttataa ttttttagat attctaaagt ggttcgaggt gattgatctt
    21961 tatcctcacg atcttgaaca aaatctttta tataatcggg catatgaagt atgattgtat
    22021 ctattttttg atatatttct gtatttttca tgtcattcat cctttcaata agtaggggag
    22081 aagagtatct ctataattgg actataccaa ttatagaatg ttttgtcaat tggtatgctc
    22141 taaaatttat taatttgttt caaaaaaagc atataaacag gtatacgttt aata
//
LOCUS       DAXLPQ010000043        22029 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.043, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000043 DAXLPQ010000000
VERSION     DAXLPQ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.043"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(61..1371)
                     /locus_tag="ACF3UO_001956"
     CDS             complement(61..1371)
                     /locus_tag="ACF3UO_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFD3657946.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1383..2801)
                     /locus_tag="ACF3UO_001957"
     CDS             complement(1383..2801)
                     /locus_tag="ACF3UO_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3657947.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3041..4609)
                     /locus_tag="ACF3UO_001958"
     CDS             complement(3041..4609)
                     /locus_tag="ACF3UO_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFD3657948.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4613..4894)
                     /locus_tag="ACF3UO_001959"
     CDS             complement(4613..4894)
                     /locus_tag="ACF3UO_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFD3657949.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4891..5814)
                     /locus_tag="ACF3UO_001960"
     CDS             complement(4891..5814)
                     /locus_tag="ACF3UO_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFD3657950.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5811..6689)
                     /locus_tag="ACF3UO_001961"
     CDS             complement(5811..6689)
                     /locus_tag="ACF3UO_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFD3657951.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6676..8013)
                     /locus_tag="ACF3UO_001962"
     CDS             complement(6676..8013)
                     /locus_tag="ACF3UO_001962"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFD3657952.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8016..9119)
                     /locus_tag="ACF3UO_001963"
     CDS             complement(8016..9119)
                     /locus_tag="ACF3UO_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3657953.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9193..10701)
                     /locus_tag="ACF3UO_001964"
     CDS             complement(9193..10701)
                     /locus_tag="ACF3UO_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3657954.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10667..11359)
                     /locus_tag="ACF3UO_001965"
     CDS             complement(10667..11359)
                     /locus_tag="ACF3UO_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFD3657955.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11381..12355)
                     /locus_tag="ACF3UO_001966"
     CDS             complement(11381..12355)
                     /locus_tag="ACF3UO_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3657956.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12655..13527
                     /locus_tag="ACF3UO_001967"
     CDS             12655..13527
                     /locus_tag="ACF3UO_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657957.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14109..16307)
                     /locus_tag="ACF3UO_001968"
     CDS             complement(14109..16307)
                     /locus_tag="ACF3UO_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657958.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16539..17531
                     /locus_tag="ACF3UO_001969"
     CDS             16539..17531
                     /locus_tag="ACF3UO_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657959.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17591..19012
                     /locus_tag="ACF3UO_001970"
                     /pseudo
     CDS             17591..19012
                     /locus_tag="ACF3UO_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
     gene            19005..20504
                     /locus_tag="ACF3UO_001971"
     CDS             19005..20504
                     /locus_tag="ACF3UO_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFD3657960.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20543..21937
                     /gene="uxaC"
                     /locus_tag="ACF3UO_001972"
     CDS             20543..21937
                     /gene="uxaC"
                     /locus_tag="ACF3UO_001972"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFD3657961.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6670 a         4493 c         3823 g         7043 t
ORIGIN      
        1 atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt
       61 tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca
      121 gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg
      181 gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc
      241 tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc
      301 tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc
      361 tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat
      421 ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat
      481 cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatt
      541 gatatcgtga atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc
      601 gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc gattgactct
      661 tgcaccattg ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc
      721 acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc
      781 atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa
      841 gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata
      901 cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg
      961 atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg
     1021 gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac
     1081 attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg
     1141 aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact
     1201 cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa
     1261 gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt
     1321 gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct
     1381 ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc
     1441 agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag
     1501 tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta
     1561 gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt
     1621 cctacttttc tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc
     1681 ttatattgat gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa
     1741 ccagatccta aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga
     1801 aggaaataca tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc
     1861 tttttaccaa ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg
     1921 taagtaaata aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa
     1981 taagtcatat tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact
     2041 aaaataatca gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt
     2101 tcgtttttga caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca
     2161 aatgctattg cagcacatcc gattgaaatc caaaagaaat gattccctga aacgacttgt
     2221 tgtccactct tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg
     2281 ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag
     2341 ctaattgctg ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa
     2401 acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat
     2461 ggcaaaaaca aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga
     2521 ataaatcggc cagtttctgt taactctgag acatcacata atcttccaac catcacatca
     2581 gcaaacgcat ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg
     2641 ccaagaacat tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag
     2701 ttacctagat caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct
     2761 ttttttactg tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct
     2821 tctagtaaac gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg
     2881 gctttttatt gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc
     2941 ataagattga taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag
     3001 tgaaaataag ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat
     3061 catacttgaa aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg
     3121 ctatcccgat aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac
     3181 ctactttctt ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct
     3241 ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt
     3301 gtgctactcc gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag
     3361 taacataaca ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat
     3421 taaaattatt aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc
     3481 gaatagctaa caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta
     3541 aaaaacctgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat
     3601 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     3661 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     3721 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     3781 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     3841 tttgtactaa gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     3901 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa
     3961 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     4021 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     4081 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     4141 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     4201 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     4261 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     4321 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     4381 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     4441 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     4501 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     4561 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     4621 cttttctcat tcttactcga tataaactga atgccccagc tgctaaaaaa gcaagtgaaa
     4681 taaacaacac aacggcaaac agaccagtca tgtcctgtaa taatccaaat gtattttcta
     4741 aagacaaagt tgaatgatct acagcaagcg actgataact ttttttaaac tctgacgcag
     4801 acatattact taaagtaact gctaacccgc caaagaaaat caaagataga ctgccaccga
     4861 ccattcctag caatagttcc cattttcttt tcatttctga accccctgct tttctaaatg
     4921 tatccattca ggtcttttga tcgatgtttc ataattgtta ttacgttcag agaatttgac
     4981 agtctgttca tttttcttgt catcccaatt atcccaacca gttgggtgaa catgcccacc
     5041 tatcttacac gcttcaaata agacatttgc atacggacgc cacggtcttc ctaaatagac
     5101 gtttctagta tcaggttctg cagtcaaggt acagctttca aaacgatacc ctgttttttg
     5161 atttttcggc gtagatgctg ctgtgatgta tccaggattt ttactggcta agctatggat
     5221 atgacactga tgaaaaacgg catctgcccc accaaatatg aaatccaccg ttccttcaat
     5281 ccagcaatat tcataggtct gacgacaata ctcaggattg gcagaagccg gtgtacaaaa
     5341 aggagtacca tctttttgca aatcaggcaa cggacccgtg cataaggtat cctgataacc
     5401 agatagtcga cagtttttta aagatacgcg atctcctgaa ttgaataaag caacagcctg
     5461 tcctaccttt tctcctggac ctgctgtatt ttcgatgtga agattttcta atacgacatt
     5521 cgatccttct aagaaaaaag tagcacttcg gaaagtccct aactggctac cgtcaagata
     5581 ctcctgtttt gcaaaacgat taccggagat aactactgtt cctgctccca caagtttaaa
     5641 attggataat ctgctttcta tatattcatc atatcttcct tcttttacta tcaagacctt
     5701 tggatggcta tccggcaggc ctgccaaata atcgattcct tcttggatag tttcaaaatc
     5761 cgtcggggta tctatagcat tctttccaat tatcagtttg tctttcatcc tcataaatgc
     5821 tcccttatga attgtttcca aatatttctc atttcttgtg tttccatatg accgcctgtt
     5881 aaagaaaaag aagaaaagtt ttctggacta cccattgatt gatacttttt gtccagccct
     5941 tttctcagct tcagtacgcc ttcgtccaag cacatcgtat cgttttttcc aactaagcta
     6001 agacgagggc gcggagcgat tttttcttgg attgctaacg ttgtataagc tgtcaataga
     6061 tttggcacat agtaataaaa cccatgatga tctaggcggc gatgtagcaa aagtgtttcg
     6121 atgtccacct gtgccgctag atcaatacaa actttgacac gagaatccaa tgctgtcacc
     6181 caccagctta ataagcctcc catagaaaga ccaatcgttg cgagccgttg agtatctgtg
     6241 tcttcccttg tctccaaata atcgatcaag ctgatcacat cataaatacg cattccccat
     6301 aacgtttttc ctgttaataa aaattgtttg aacaactcgc tttcagaaat acctccgcgt
     6361 tcttcaaatc cccaagcatc aatcgaccaa acagcatatc ccattcctgt cagtacttct
     6421 gcaaaagatg gagaagctaa gtaaggagca ccatggatca attcactttt cccgactgaa
     6481 aaatctccgc cgtgagaatg caggtaaagg accgtcggaa acggtccttc tttttctgga
     6541 taagcataga gggctggtac tgtttccaat tcatttaagt acaattgata gtattcaagc
     6601 ataaaaccgt tttgtttttc tcggtataat cgttttccac taggggtatg tctgctagat
     6661 ggagcaccta aaaaatcatt caactgcata agcaaagttt ttacgaacaa ccagttcatc
     6721 catattttct gattgatttg attggaattt ctcaatactg atttctttag tattttctaa
     6781 tagaaatgct ggtccctcgt gattttcaat cgacatctgg ttaaaggaaa ccttacccgc
     6841 aaagccaata taaaatcctt gtctgctcat ttcctctatt cctgtcatca tagcaggaac
     6901 accgggaact gcatcttggg ccatcgagac atcgatattg tcaaatgtga tttcttgtat
     6961 gaattgttcc gctaatccat aaataaaacc tgcagaagca tggacattcc ttgccgtgat
     7021 attcgaaaaa tggatccttc tgaatgctga tgtccgttca tctatcggat aagccttttt
     7081 ttcccataca tacggttctt tccctcgcgg accacagaaa taataaagat tcagtataaa
     7141 tggacacatc acattatcca tgactatatt ggatactcga atatcttcaa cgatcccgcc
     7201 tcgacctcgt ctagatttca atcgtattcc tcgatcagtt tcttggaaga tacaatttga
     7261 aatggtaata ttacgaatac taccactcat ttcacttcct aatacgacac cgccatgtcc
     7321 atggaccatc gtgcaatttg tgatcgtgat attttcgcaa gcgatccttt cgtacgtatc
     7381 ttcagtccct gccttgattg caatacagtc atctcccacg tcaatatggc aattactaat
     7441 acgcacattt ttgcatgatt ctggatcaat tccgtctgta tttggtgaat ccgctgggtt
     7501 caagatcgtc aagttatcaa acgttgcatt actgcaaaga atcgggttga tcgtccaact
     7561 tggtgactgg atcaatttaa tatctttcac agtaattcga tgacagttat ggaaactcat
     7621 caatttagga cgaggataag cgagattatc tggttcattt ctaaaagtat gccaccattt
     7681 ttttccattt ccatctaatg taccgaaacc agtgacagag atgttctcta cattttgagc
     7741 atagatacag gaagcataaa cttttcgatg gactccttcc caacgtgaat gaacaacagg
     7801 ataatctttt ggatcgtcag agaatttcag aaccgctcct gcgcttaaat gaagttcgac
     7861 attgcttttt aaaaataaag ctcctgttag aaattcacct gctggaacaa ctacggtccc
     7921 gcctccgtca cttgctgcag catcaatggc ttgttgtatt gcttcagtat tcaattcatc
     7981 aattgatgcg ccaaatgtca aaatatcata catatttata atgcctccac ttcaatcaat
     8041 gcttgcaaga atgcaccaac gcctttttga tcattacaaa taattggttc actgatgtag
     8101 taagcatatg aaccatctcg ctgatctgct ccgcctaacc ctgctacttg acagttttta
     8161 ttcaagttca gccagccttc ttttgtttcc agaacaaatt catcaagtaa tccttgatgt
     8221 gatttcttca cttgtggaag ccattcttct ttgttcagca gtcccaaacg tattccttta
     8281 gccattgcgt aaacaaacat actactgccg gaagcttcca gataatttcc tttccgtttt
     8341 gtttctgttg ttacttgata ccatgtcccg ctgttttctt cttgatatgg aagtaatgca
     8401 gccagtgtct tttctagaat ttctttcagc aaagaacaat ctgtttcttc atgaagtaat
     8461 tcataggtat ctgctgcagc catcaaatac cagccaatcg atcggctcca aaaatgatgg
     8521 gatagacctg tttttggatc agcccatggt tggaccttct tttcatccca tgcatgaatc
     8581 agcaaatttg tttttggatc gaatagatgt ttataactga tttcaaactg tctcaaaaca
     8641 tcttggtaat ctttttcttc actaaaattc tggataaatt cagcataaaa aggagaaccc
     8701 atatataagc catccaacca aatttgataa ggataaattt ctttatgcca aaaagctcct
     8761 tcggatgtgc gtggatggtt tgccaactgc tgggaaagga gttctgctgc ttttttatat
     8821 ttttcttcgc ctgtttcttt gtacaataaa aagaaaagct ttcctgtatt tacatggtcg
     8881 atattgtatt cttcaacgct gtagccacgg atcgttccat cttcttgcac gaaatagtcg
     8941 atattgtctt ttatgaaatc aaaataaatt ttttcttggg ttcgttccca aagtaattgg
     9001 aaccctttaa gtacgacgcc atagtcataa gaccattttc ctttatacca cttttcttca
     9061 tataagcgag gtgttctttc catgatactt tttgctaatt tctttgacca gttttccatt
     9121 atttgctctc ctttaaaaat taaaatagga tttgggacaa ataccaagaa gtatttgtcc
     9181 caatcgtcta tattactgtg ccgctgcttt gtatgcttcc tcgtactctt gtgtgattcg
     9241 atcgcctcct tgtgctttcc agtcttctac agcttttttg aatccatctt cgtcaagctg
     9301 tcccatgatg tattgcaccg tagcatcaat gacgattttt tcaatttctg atcctacttc
     9361 attgttcgtc ggtgaatcca atggcacaga aggatccatt acagcaaatt cttcattttc
     9421 tttgatcaat tgattagaga attctttttc agggtctgta tctttgaaag agaacgtcac
     9481 ttcactagga cgagagcttg ataacggttg cacctcttgt tgccaaagat ccatatcgat
     9541 aaattcgata gaaccatcat cattcaattc ataatgcgtt ccttcgatac cgccagtcat
     9601 caatttatac acatcttctt ctaaaagatc atcaacaaat tgaagtaatt tcttcaattg
     9661 tgcttcgtct tttacttgag atttgggaaa tgctagcaag ccgccaatac catttccttc
     9721 tgaccaaaca tgataaccgc cgccttcacc atctgagatc ttgtttacag gcactaattc
     9781 catatcatct tgaatacctt gacccatcgt cttcagattc ttgatatcca ccattccagt
     9841 gtagattcca gttcttcctt gtgcaaattg ttcttgctga tcagtctttt gggtaactgc
     9901 aaagtcttgt gccaaatagc cattctcaaa tagatctctt gaaaaattca aagctttcat
     9961 atactcttct gtatcaaatt ctggagtgaa tttgccatta tcgtctacag cccagccatt
    10021 tggtgctcca aaataagaag tgaaaagttt aaagctggta taacgaatat cactaggcgc
    10081 acgatcgcca aaaccaactg tgtcgtccac accatttcca tcaggatcgt tttctgtaaa
    10141 ttgtttagct acttcataaa gctcatccat ggtagttgga acatctagtc ctagattatc
    10201 caaccagtct tttcgaatga ctaagccagc acgagcgtag tctttttgta tcggtacgcc
    10261 gtacaaggca ccgtcgatac tcgcagcttc gattctatct tcagaaattt gacttaaatt
    10321 tttatagtct tttaaatatt ctgatacatc ccagaatacg cctgatttta acgcattgcg
    10381 gacagaagag tttttcaaca tcgcaatttg aagtgtaacg atatctccta gttcatcaga
    10441 agccaatgca gttgttaatc tttcttcttt tgaagcatca ggaatccagt tgaatgtcag
    10501 ttccgtatcg gttttttctt cgatcaagtt cacaatcgtg tctgtaggcg gtgaagcatg
    10561 atgcaaaata tttaaccaag tgattttagc ttttccatct tctgtctctg aagaactgtt
    10621 acttgaactg ctgccgcatg cggcaagtgc tagaattcct gcaaaactaa gacctaattt
    10681 tacgagcgtt gcttttttca taaattttct ccttcactgt tttaataata tttttgtttt
    10741 cttctgtttt ttctgtatat gagttcttcc attccaaatg gcaaaatata gaatttgctg
    10801 tccacgtgac tgcggaaaag aagagactgc caccgataaa ggttaaaaca cctggcattg
    10861 tttggatgat catcagataa atccctacca tacttaatat caacactaat gagtaatgaa
    10921 gatgtgagaa tccgaataaa aatgccattt tcattttgaa aaaatatcct ttccaatcat
    10981 aatgagccat gattgggaaa atatagagtg ctgagagcac atatatgaac gcagcaatat
    11041 acaaagcgat cctaagatac caattgtgta tgaaagaaag atccacaagt aaaacaatcc
    11101 cgatggcgcc atatatccag ctcatcagca aggtttcacg atagttttct ttaaaatatg
    11161 tgaagtacgt tttcgtcaaa ggaaacgttt cttttgagcg cagccatttt ctaatcactg
    11221 caaccatcgc atacgatgca ggaccgaaag taaaaactcc caaacctgcg atgactaaac
    11281 cgccccacag aaaattcaaa taaaccaact gtaaaatacg atttagcctt ccgtttattt
    11341 tatctaatga ctgcagcata tctttccctc tctttctatc ttagtaaacg ccgtcttctc
    11401 ctagcttttt ggcaatctta ttagctaaaa ttaccataaa caatcctacg acccctttaa
    11461 acaatcccat tgctgtactg aaacttaact gtccattctt caatccagct gtataaatat
    11521 aggtgtcgaa aatttctgca acgcttcgat tcaatgaatt caataacaag tacatatgct
    11581 cgaaccctaa gtctaatgtc tgaccgattt ttagaatcag caaggtaatg attactggac
    11641 gaattgccgg caatgtaaca tgccatgttt tgcgtaagcg tcctgctcca tccatttctg
    11701 cagcttcata caactgtgta tcgactgcag ttatcgctga aaggtagatg atcgtagacc
    11761 agcccaactc tttccagatc acttgtccga tatatactgt gcgtgtccat tcaggggatg
    11821 ttagaaaact gattttttca aatcccattg ttgcaaggaa ttcattcaat acccctccgt
    11881 caacattcaa aaatacataa gtaatcgaaa caatgattac ccaagacatg aagtgaggga
    11941 tgtaaatgat cgtttgaatc ccgtttttca atcgtttgtt cgttacttca tttaatagta
    12001 aagacaaaat gattggcatc ggaaaaaaca cgaagatatt taatccgaac aagatcaacg
    12061 tatttcttaa taatgtaaag aatgtcggtt ctgtaaacaa acgaatgaaa tgtttgaaac
    12121 cgacccaagg acttcccatt attcctaaaa atggttgata atcttgaaaa gcaataacga
    12181 gtccccccat aggaagatac ctaaaaatca agaaataaag gactcccggc agaatcatca
    12241 catataaaaa tttattcgtt ttgattcctg caattatttt ttttcgtctt ctgagctttt
    12301 cttctttttt cgatagcgtc agttgaaatg gttcttgttt ctttacactt tccataagcc
    12361 cctccttagt tttgtgaatg tttgctgctt atgacttcat gatagataac tatctgaatt
    12421 acgtatataa tcatttttat cgtaagtaaa aacgcttaca tagcaatgat ttttgtgcta
    12481 tacaaaacga taaagtgtat tttttcacaa ataaactacg catagcaaac cttctatttt
    12541 tttctatctg acacttagca taggaaatga ttatatacgt aatctttcac cgatgataaa
    12601 ttgaacatat agaaacagaa acatttaatt tattttgagg aggagcctat ctatatgaaa
    12661 aagaaagtct ctataggaga aagaagtttt acacttttca acaatacgtt tctaattttg
    12721 ctagctttga tctgtatcgt tcctttttta aatatcatcg ctacatcttt tgcttctaca
    12781 caagaagtcg tcgcgaaaaa gtttatcctt tttcctacta ccttttcttt agacgcgtat
    12841 cgctacattc tttctacgcc gaccattttt agagcacttg ctgtttcgat tggtgttaca
    12901 ggtgtcggaa cgatcgtcag tatgtgtgca acttcactga tggcctacgg tctttccaga
    12961 aagtatttgt ttggtcgagg tttcgtcaac tttcttgttg tattttctat gttgttcagc
    13021 ggggggatga ttccaacgtt cttagttgtt cgttctctag ggctggtcaa ttcttactgg
    13081 gccatgatcc tgcctgtggc tgttaatgca atgaatatga tcattatgag aaactttttc
    13141 caagccttgc cggatagttt ggaagaatca gcaaaaatgg atggttgcac agattttggt
    13201 gtatttttca aaattatgct gccattagct ttaccgtcta ttgctactat ctcgcttttt
    13261 tatgctgtta cttactggaa cacttatatg actgctattt tgtatatcaa cgattcatct
    13321 aaatggccga tacagattct tttacgccaa atcgtcattg tatcaagtgg gatgcaagca
    13381 gaaagtagtg ccgttgatgt gattccacca gcacaaacag ttaaaatggc tgttatcgtt
    13441 attgcaacag tgcctatgct gattgtttat ccttttgttc agaaatattt tgtcaaagga
    13501 gcactcgtag gttctgtcaa agggtgatta tgtactgaac gcaaaatggt agttgtgtca
    13561 gaagtggtca gcttcaagaa ataagaaggc atttacgaaa attgcttctt aaatttttgt
    13621 gaaatttcgg cttatttttc gaagaatcta ctcctggaac accgtgtatc agaggttgtg
    13681 aaagagacgt tcagccttga gcgatgataa aaactctcac aaacattgcg acgagtaacc
    13741 cacaggagca ataagaagcg attttgaaaa atagcttccc atatttcaca aaattatgcc
    13801 ttattgtcga tagcctgtct cttgaacgcc atttattcgt aaaaaagaac tgtgacaaga
    13861 cttttgtcac agttcttttt gcgtgcttag ccttgaaatt taactatcca taaatacaaa
    13921 tactagggtt attctaactt cttttattgc ttgaatcagt ccacaagaaa aacagcctct
    13981 tgattaaacg gcgtttatct tgttgattct gcggcaataa aatcagccag cagcaaaaca
    14041 tgaagtgctg ttttttgctg tcctctttta ttgcttgaat cagatcacaa gaaaaacagc
    14101 ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc cttcttttta
    14161 aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat ctcttttacg
    14221 gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt ttgaacaaaa
    14281 tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt agggttataa
    14341 tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt gtagacgata
    14401 tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg agagcattct
    14461 gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg atgataattg
    14521 ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc tactcccaat
    14581 aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc ccgactcaaa
    14641 ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt cttcacttcc
    14701 tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg atatctaata
    14761 agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga acttggacca
    14821 gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt gctttcattc
    14881 agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta ttcttttaca
    14941 cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc atcatcttta
    15001 tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag cattcgattt
    15061 tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc
    15121 ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata gcagtcattt
    15181 tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt
    15241 ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac taagtgtgca
    15301 cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa atctagttct
    15361 ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga aatcggacgg
    15421 gcaaatctgt ccgaaaataa gtaggaaaaa agaccaatga gtcctaccag tgttaaagac
    15481 actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact agagtcaact
    15541 tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt tttatctttt
    15601 tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac agttggttgc
    15661 tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc aatagaaagt
    15721 atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat cgtagcaatt
    15781 cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg
    15841 tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg atacttttca
    15901 acttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt accagccaaa
    15961 ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt tagttctttc
    16021 ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag
    16081 aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat tttccattca
    16141 acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact cgattcgatc
    16201 gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac ggctcctaat
    16261 aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt cttcctctcc
    16321 tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct aattaaatga
    16381 gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa tttttaacgt
    16441 gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa tatgatgaat
    16501 gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc aaagatatcg
    16561 ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac agcagtttaa
    16621 taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat tattcgccaa
    16681 actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta tttttctcaa
    16741 gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc atccattcag
    16801 tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat ttaacagaaa
    16861 tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat gatcagcctt
    16921 tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg
    16981 atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag gcagtagatt
    17041 acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa aattttcgtt
    17101 cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc atccctgtca
    17161 atctagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa aacatggaat
    17221 acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac gacatagcga
    17281 ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac atttctctga
    17341 tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc accgtacgta
    17401 agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg atcgaaggca
    17461 ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt gagtcgatca
    17521 attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat aacacagaaa
    17581 ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa
    17641 agttctttag tttggtgaag gcaattttat gcgtggattt attgattggc agattcagca
    17701 gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg
    17761 tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac aaggactcag
    17821 caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa tgatcaatcc
    17881 ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg cctatatcgt
    17941 ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa cagatactcc
    18001 cccacagagc ttcccgggca aactgacagc ctttttatac cgacgtttca aattaaacaa
    18061 agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac gtctaaaaga
    18121 aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg agtggttaga
    18181 aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga
    18241 agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg tcaaagcaga
    18301 accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac taccattcaa
    18361 acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg aacgtaaggt
    18421 gcatttgctt aatggaccgc atacagcgat ggtccctctt gctttgttgg cggaattgga
    18481 aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc agttattcaa
    18541 tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt atgctgacca
    18601 aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga tttcattaaa
    18661 tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata tcgaagaaca
    18721 aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta tgtatcgagg
    18781 cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg atgcttggtc
    18841 tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg gagaagattt
    18901 gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa
    18961 aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc
    19021 aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc cctattccaa
    19081 aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat atcccgcaag
    19141 gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa tatggctatc
    19201 caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact cataatgtaa
    19261 aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat ccaagtcatt
    19321 acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc
    19381 gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg
    19441 tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt acgattttaa
    19501 agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga gaaattttag
    19561 cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta ggttgtgaga
    19621 acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat
    19681 ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta ttagaagagc
    19741 ttttaacagc ggcggaaaat gaccagcgca tatcagtccc gctctctaag ttgaatgtcg
    19801 gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct ttacttggtg
    19861 cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa gtgccagaaa
    19921 tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa
    19981 tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa ccagtttacg
    20041 aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat aagtctttag
    20101 gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa
    20161 tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta gctgcctctg
    20221 ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg actccgtttg
    20281 gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc
    20341 attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta atcttagaat
    20401 cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg
    20461 acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca taaaacagta
    20521 taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa aagacgattg
    20581 ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt atcactgtca
    20641 cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag aagcttggtt
    20701 aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat
    20761 cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat
    20821 tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct tcggtattga
    20881 cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg aaattttggc
    20941 agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac
    21001 aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg aagaaccaga
    21061 tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa aagaaggatt
    21121 taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca cctatcaaga
    21181 actgatagaa gtcttagggc agcggataga atacttccat caacatggat gtcgtgtttc
    21241 cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat tagaagagat
    21301 ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg cttatcttac
    21361 agaaacactg atacatttga cccacttcta tcattctcat aattggacga tgcagctgca
    21421 catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc ccgataccgg
    21481 ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat tgaaccgtgc
    21541 agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga atgactatcc
    21601 tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac tgcagttagg
    21661 ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga cacaatttgc
    21721 tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa gtttcctgtc
    21781 ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat
    21841 gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag cgattagtta
    21901 tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta acagtaacga
    21961 atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga gaagaagacg
    22021 gaccaaatt
//
LOCUS       DAXLPQ010000044        21969 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.044, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000044 DAXLPQ010000000
VERSION     DAXLPQ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.044"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            3..815
                     /locus_tag="ACF3UO_001973"
     CDS             3..815
                     /locus_tag="ACF3UO_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFD3657962.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            812..1612
                     /locus_tag="ACF3UO_001974"
     CDS             812..1612
                     /locus_tag="ACF3UO_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFD3657963.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1773..3041
                     /gene="rseP"
                     /locus_tag="ACF3UO_001975"
     CDS             1773..3041
                     /gene="rseP"
                     /locus_tag="ACF3UO_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFD3657964.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3109..4818
                     /locus_tag="ACF3UO_001976"
     CDS             3109..4818
                     /locus_tag="ACF3UO_001976"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFD3657965.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5030..9388
                     /locus_tag="ACF3UO_001977"
     CDS             5030..9388
                     /locus_tag="ACF3UO_001977"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFD3657966.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9533..10006
                     /gene="rimP"
                     /locus_tag="ACF3UO_001978"
     CDS             9533..10006
                     /gene="rimP"
                     /locus_tag="ACF3UO_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFD3657967.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10029..11204
                     /gene="nusA"
                     /locus_tag="ACF3UO_001979"
     CDS             10029..11204
                     /gene="nusA"
                     /locus_tag="ACF3UO_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFD3657968.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11226..11519
                     /locus_tag="ACF3UO_001980"
     CDS             11226..11519
                     /locus_tag="ACF3UO_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFD3657969.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11516..11827
                     /locus_tag="ACF3UO_001981"
     CDS             11516..11827
                     /locus_tag="ACF3UO_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFD3657970.1"
                     /translation="MNTVNRQEAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11840..14146
                     /gene="infB"
                     /locus_tag="ACF3UO_001982"
     CDS             11840..14146
                     /gene="infB"
                     /locus_tag="ACF3UO_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFD3657971.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNPNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14173..14520
                     /gene="rbfA"
                     /locus_tag="ACF3UO_001983"
     CDS             14173..14520
                     /gene="rbfA"
                     /locus_tag="ACF3UO_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFD3657972.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14677..15133)
                     /locus_tag="ACF3UO_001984"
                     /pseudo
     CDS             complement(14677..15133)
                     /locus_tag="ACF3UO_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            15298..17660
                     /locus_tag="ACF3UO_001985"
                     /pseudo
     CDS             15298..17660
                     /locus_tag="ACF3UO_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            18028..18951
                     /gene="truB"
                     /locus_tag="ACF3UO_001986"
     CDS             18028..18951
                     /gene="truB"
                     /locus_tag="ACF3UO_001986"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFD3657973.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18955..19896
                     /gene="ribF"
                     /locus_tag="ACF3UO_001987"
     CDS             18955..19896
                     /gene="ribF"
                     /locus_tag="ACF3UO_001987"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFD3657974.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20248..21033
                     /locus_tag="ACF3UO_001988"
     CDS             20248..21033
                     /locus_tag="ACF3UO_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3657975.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21046..21897
                     /locus_tag="ACF3UO_001989"
     CDS             21046..21897
                     /locus_tag="ACF3UO_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFD3657976.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
BASE COUNT         7476 a         3844 c         4840 g         5809 t
ORIGIN      
        1 gaatgttacg tttttttccg caaaaaaaca aatatattca agaaaaaagc gaatttcaat
       61 ttaataccga tggaccaatt cctcagcaca ttgccatcat catggacggc aatggtcgtt
      121 gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa agaaggcatg gaaacagtaa
      181 agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt gttgacgctt tatgcctttt
      241 cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt tctcatgcaa ctacctgtcg
      301 acttctttga tacgttcgta ccagaattga ttaaagaaaa tgtcaaagtt catgtcatgg
      361 gttatgaaaa cgtattgcca gaacatacgc aagatgctgt aagacgtgca attgagcaaa
      421 caaaaaacaa tactggaatg gtattgaatt ttgctttgaa ttatggaagc agagcagaga
      481 tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa aggagaaata cacgcagaag
      541 aaatcgatga tgaattgatt gctaagcatt taatgacagg tttcttgcct aaagagttac
      601 aagatcctga gctgatgatc cgtacaagtg gagaagagcg aattagtaat tttctgttat
      661 ggcagatcgc atatagtgag ctgtatttta caaaagcgct ttggcctgat tttgatggtg
      721 cgcatcttga agaagcaatc gcctcttatc aaaatcgaga ccgtcgattc ggcggtgtaa
      781 aaaaaacaga agatgagaaa ggggatcagt catgaaacaa cgtgtggtca cagcagccgt
      841 ggcgctagtc ttgtttattc cgattatatg gatcggaggc atagcggttg agcttacagc
      901 agcaatctta gcagtaatag gagtttacga gctgtttcgg atgaaaggat tgacactctt
      961 aagttttgaa ggagttttat ccgccgttgg tgcagtgtta cttgttttgc caaaagaaag
     1021 atggtttttc tttcttccag agaatgtaag tacatttatg ttattttatc ttatagttat
     1081 gattctttta ggaacatcag ttatttctaa aaatacgtat acgattgatg aagcaggttt
     1141 tcctgtgctt gtcagcttgt atgtgggaat aggtttccag aattttgtca atgcacgaac
     1201 agaaagcttg gctgttttga tatttggtct atttattgtt tgggcaactg atatcggagc
     1261 atatatggtt ggtcgacgtt atggtcagca taagttaagt cctgatattt cgcccaacaa
     1321 aacgattgaa ggtgcgctcg gtggtattgg tagtgctgtt gtagtcgcat ttctttattt
     1381 attgctatac ccagcaaaag aactatttaa tcatggtatg tttgtcatgc ttctgatgac
     1441 gattattttt tcagcagtcg gacaatttgg tgatttggtc gaatctgcaa tcaaacgtca
     1501 ttatgatgtg aaagactcgg gaaatatctt accaggccat ggtggaatct tagaccgttt
     1561 cgacagtttg ctgtttgtat ttcctatcat gcatttattt ggcattattt agtaagtata
     1621 cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt tatttttcat tatattgata
     1681 ctattggtgt ctttggtata ctatggtaaa attatagtgt tttatcgttg ttttataaaa
     1741 aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac gattctgaca tttatcatcg
     1801 tttttggtat attagtgatt gttcatgagt ttggtcattt cttctttgcg aaacgatcag
     1861 gaatcctcgt tcgcgaattt gctatcggta tgggtccgaa aatttatggg catcaagcaa
     1921 aagacgggac aacatatacg cttcgcctat tacctattgg cggttatgtt cgaatggcag
     1981 gcaatgggga tgatgaaaca gaaatggcac caggaatgcc tctttctctt ttactaaatt
     2041 ctgacggcat cgtagagaag ataaatttaa gtaagaaaat ccaattgaca aatgctatcc
     2101 cgatggaatt gagccgttat gatttagaag atgagctgac tatcactggt tatgtgaatg
     2161 gagacgaaac agaagtagta acctaccctg ttgatcatga tgcgacgatt attgaaaacg
     2221 acggaacaga aatcagaatt gcgccaaaag acgtacagtt ccaatcggct aaattgtggc
     2281 agcgtatgct gaccaacttt gctggaccca tgaataactt tattttggca atcctgttat
     2341 tcatcattct ggcatttatg caaggtggtg ttcaagtgac gaacactaat cgcgtaggag
     2401 agatcatgcc taatggagct gcggcagaag caggcttaaa agaaaatgat gaggtagtca
     2461 gtgtggacgg aaaagaaatc cattcatgga atgatctgac aacagtcatt acgaaaaatc
     2521 cggataaaac attagacttt aagatcgaac gagaaggtca ggtgcaatct gtcgacgtga
     2581 caccgaaatc tgtagagtca aatggcgaaa aagttggcca acttggtata aaagccccaa
     2641 tgaatacagg ttttatggat aagatcattg gagggacgcg tcaagctttc agcggttcat
     2701 tggaaatttt caaagcctta ggatcactat ttacaggttt cagtttagat aaattaggcg
     2761 gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa tcaaggtgta acaactgtta
     2821 ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt caatctgctt ccgattcctg
     2881 ccttagatgg cgggaaatta gtcttgaata tttttgaagg gattcgcggg aaaccattaa
     2941 gtcaagaaaa agaaggaata ttgacattag ctggctttgg atttttaatg ttgttgatgg
     3001 tgctagttac atggaacgat attcaacgat tctttttcta gaaaaagttg acaaataggg
     3061 tataataaca aacgataact attttgagga aataaaggag tatatagaat gagacaatca
     3121 aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg cagaagtatt aagccatcaa
     3181 atcttgctaa gagctggata tatccgccaa gtatcagcgg gtatttattc atatctgcca
     3241 ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc gggaagaatt tgaaaaaatc
     3301 ggagcggtag aaatgctgat gcctgccatc ttgccagcag aactttggga agaatccggg
     3361 cgttacgaaa catatggacc aaacttgtat cgtttcaaag accgcaatga tcgaaaaatg
     3421 atccttggac caactcacga agaaactttt actgatttga tgcgtaatga aatcaattca
     3481 tataagaaat tacctttaaa tctttatcaa atccaaccta aatatcgtga cgaaaaacga
     3541 cctcgcttcg gtttgcttcg cggaagagag tttatcatga aagatgcgta ttctttccat
     3601 gcaacggaag aaagtttgga cgagacatat aaagattacg aaaaagccta caccgaagta
     3661 ttcaagcgtt gtggcttaga atttcgctcg attatcggag acggtggcgc aatgggcggg
     3721 aaagactcaa aagaattcat ggcgatctca gaaatcgggg aggatacgat ctgttattcg
     3781 actgaaagtg attatgctgc aaacttggag atggctacaa gctactatgt atcaaaaaaa
     3841 tcgcatgaaa cacagcttga attggagaaa gtagctacac ctaacgtaaa atcaattgac
     3901 gaagtagcag atttcttttc tgttgaacct caaaaaatca tcaagtctgt attgttcatt
     3961 gcggatgaac aacctgtcct tgttttggta cgcggagacc atgaagtcaa tgacgtaaaa
     4021 ctgaaaaact ttttatctgc tgacttttta gaagaagcaa cagaagaaga agcacaaaaa
     4081 tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg tttcagatga cgtaaaagta
     4141 tatgcagacc gttatgtcca agatttagcg aatgccatta ctggagcgaa cgaaacagga
     4201 ttccactata aaaatgtgaa tccagaacgc gatttcactg tactttctta tgaagatctt
     4261 cgttttgtac aagaaggaga tccttcacca gacaacaatg gtgttcttgc ctttactcga
     4321 ggaatcgaaa tcggacatat cttcaaaatc ggcactcgtt acagtgaatc tatgggagca
     4381 actgtactag acgaaaatgg acgagaaaaa tttgtgatta tgggctgtta tggtatcggt
     4441 gtaagtcgtt tattatcagc aatcgtagaa caacattcag atgaacaagg aatcaactgg
     4501 ccaaaaggaa ttgcgccatt tgatttgcat atcgtccaaa tgaatctaaa agacgaatac
     4561 caaacaaacc tgacgaatga actagaagaa gcgatgacaa aagctggcta tgaagtactg
     4621 gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg attctgattt gattggctgt
     4681 ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa tcgtagaagt gaaaatcaag
     4741 aaaactggcg aaatggttga agtacgtaaa gaagaattgg tgaatacttt accaatcctc
     4801 ttgaaccaag gcgaataata agcgttaaaa cacagaaaat aaaaatagct gaatcagctg
     4861 tttttgacaa tctgatgatt cgcttttaaa attggaactg cgatttgaat cgcagttcca
     4921 attttttaat gtaaaactca gaaaaaacga gtatactaaa aggtactgaa aaagaagagg
     4981 ataagatgcg atcaattgca ttgtttctca tcagaaaggg cgtatatctt tgtcagaaaa
     5041 acgagattta tttgaaaaac tgttggaaca aatccaacta gaggaagcag aaaaaaatca
     5101 tccactgctt actgctggtg aaatggatag tgtagtggtc catcgtaaat cgcgtttatg
     5161 ggaatttacg ctgcattttt ccaaaatttt gcctattatg ctatatcggt cattgactca
     5221 gcatctgact atcgctttta aagatattgc acaagtcaaa ctgaatatct tagcagatga
     5281 ccagacattc gatgaacagc tcttgcaaga ttactgggcc caagctttgg aaaatcagca
     5341 atgcgataca ccactagcac agcaagtatt gaaaacgcag gtacctgtga taaaagatcg
     5401 taaagtcatc ttgccaatcg acagtacagg agctatttct tatttgaagc aacaatactt
     5461 gccattagta gaagagttgt tcgtcagtta cggattccca aaatttcgta tcgaaccaga
     5521 agtggatgag cagcaagcgg aacgagtatt gaaacttttt gaagaacgca aacaagaaca
     5581 ggcagaagcc tttatgaagc aagcagctga aagtctagtt gtccacgaac aaaagaaaaa
     5641 ggaaagaaaa gagcaatcgc cagctcttga aggacccatc cacatccagc taggacgaaa
     5701 tattccagcc gatgaaccaa cgacaccaat gatcagtatc gttgaagaag aacgaagagt
     5761 cacacttgag gggtacgtat tcgacaaaga agtcagagaa ctacgttcaa aacgcaagat
     5821 cttgactttg aaaatcacag attatacttc atcatttatc gtcaaaaaat tctcgaacgg
     5881 cgaaaaagat gaacaagtat ttgatgcgat cagtgtcggt agctggttaa aggtacgagg
     5941 aagtattcaa gaagatacgt ttgtccgtga tttggtcatg aatgcgcaag atatcataga
     6001 agtcaaacat acacctcgca aagattatgc tcctgaaggg gaaaaacgag tagagcttca
     6061 tgttcatagc aatatgagta cgatggatgc aacaaacagc atctctgatc ttgtggcaca
     6121 agcagggaaa tggggacacc gagctatcgc cattacagac cacggtggtg cgcaagcctt
     6181 tccggaagca catagtgctg gaaaaaaagc aggtgtgaaa atcttatacg gcgtggaagc
     6241 gaatgtcgta gatgatggtg tcccaattgc ttataatgat gcacatgaag cattgagtga
     6301 agccacatat gtcgtatttg acgtggaaac gacaggattg tctgcagtat atgacacgat
     6361 catcgagcta gccgcagtca aaatgtataa aggaaatgtg atcgaaagct ttgatgaatt
     6421 tatcgatcca ggacatcctt tgtcacgaac aacggtagat ctgactggta tcacggatgg
     6481 aatggttcga ggatcaaagt cggaagaaga agtattgcgg atgttccttg aattttcaaa
     6541 agatacaatt ttggtagccc acaacgcggc ttttgatatg gggttcttga atactagcta
     6601 cgcaaggtat ggtattcctg aagcggccaa tccagtcatt gatacgttgg aattagctag
     6661 atatctgtat cctcaattca aacgtttcgg attaggtgtg ttatctaaaa aatttggtgt
     6721 cagcttggaa cagcatcacc gagcaatcta tgatgctgaa gcaactggtc acttagcatg
     6781 gatctttgtg aaagaggcaa tggacaatca taacatgctt tatcatgatc agctaaatga
     6841 gcatatcgga gaaggagatt cttacaaaag ggctcgacct ttccatgtaa cgattttagc
     6901 aaaaaatcag gcaggactga aagatttgtt caaactgatt tcaatgtcga atgtcgaata
     6961 cttcgaacgc gtcccacgaa taccacgctc ccaattgaaa aagatgcgtg aaaatctatt
     7021 gatcggctca gcttgtgata agggagaaat attcgaagcc atgatgcaaa aaggggtaga
     7081 agaggcaaga aaccgagcaa aattctacga ttatattgaa gttatgccaa aagcggtcta
     7141 tgcgcctttg atcgagcaag aattggtaaa aaatgaacat gatttggaag aaattatcca
     7201 aaatttggta gaaatcggaa aaagtttgga taaaatcgtt gttgcaacag gtaatgtaca
     7261 ttatctgaac gaagaagatg ccatttaccg aaaaattttg atcaattcta tgggcggagc
     7321 gaatccgttg aatcgtcata gtttgccgga tgtccatttc cgaacaaccg atgagatgct
     7381 aactgcattt cactttttag gggaagaaac agcgaaagag atcgtagtag aaaatacgaa
     7441 taaaatcgca gatatctgcg aagaagtgat tccagtcaaa gatgaacttt atacaccgaa
     7501 gattccaggt tcagaagatg aaatatcaga attgagttac acaaaagcaa aacaaatgta
     7561 cggagatccg ttacctgaga tcattcaaaa acgattaaaa aaagagttga attctattaa
     7621 tggtaatggc ttctcggtta tttatctgat cgcccaaaaa ttagtgcata aaagtaatga
     7681 agatggctat ctagtaggtt cacgtggctc tgttggctct agctttgttg cgacgatgac
     7741 aggaatcact gaagttaatc cgttagcccc tcattattat tgtccagagt gccaatattc
     7801 cgagtttttt gaagatggta cgtatggttc tggatttgac atgccagaaa aacaatgtcc
     7861 aaaatgtggt gcacgcttaa acaaagacgg tcatgatatt ccatttgaga catttttagg
     7921 attccatgga gacaaagtgc ccgatattga tttgaacttc tcaggtgatt atcaagcaga
     7981 agcccataac tatacgaaag tattgtttgg cgaagactat gtttaccgtg ccggaacgat
     8041 tggtacagtc gccgacaaaa cagcatatgg ctatgtaaaa ggatacgaaa gggacaataa
     8101 tctgcagttt cgaagtgcag aagtcgacag attagcaaaa ggcgctactg gagtcaaacg
     8161 gacaaccggc cagcatccag gggggatcat cgttattccc gattatatgg atgtctatga
     8221 ttttacgccg atccaatatc cagcagacga tcaaaattcg gaatggaaaa cgactcattt
     8281 tgattttcac tcgattcacg ataatgtatt gaaattagat attctagggc atgatgaccc
     8341 aactgttatt cggatgcttc aagatttatc agggatcgat ccacaaacga tccctacgga
     8401 tgacccggaa gtgatgcgga tatttgccgg tcctgaagta cttggagtaa gtcaggaaca
     8461 aatttattcc aaaacaggga cattaggtat tccagaattc ggcactcgtt ttgttcgagg
     8521 gatgctagaa gaaacgcatc ctacaacttt tgcagaacta ctgcaaattt ccggactatc
     8581 tcatggtaca gacgtatggt taggaaatgc ggaagaattg attcgacgag gagatgcgac
     8641 actggcggaa gtaatcggct gtcgtgatga tattatggtt tatttgatcc atgctggatt
     8701 agatagcggg atggcattta aaatcatgga aactgttcgt aaaggacaat ggaacaagat
     8761 ccctgatgaa ttgcgagaaa cctatctatc ggcgatgaaa gaaaataatg tgcccgactg
     8821 gtatatcgat tcttgttcaa aaatcaaata tatgtttccg aaagcccatg ctgcagctta
     8881 cgtattgatg gctcttcgtg tcgcttattt caaggtttat ttccctattt tgtattactg
     8941 tgcatacttt tctgtacgtg cagacgactt tgatctagtc tccatgtgca aaggaaaaga
     9001 tgctgtgaaa caagcaatga aagaaatcac ggacaaagga ttagatgctt ccgtaaaaga
     9061 aaagaatcaa ctgacagtgc tggagttagc caatgaaatg ctggaacgag gattcaaatt
     9121 tggaatgatt gatttgtata aatcggatgc cgttaacttt gttattgaag gtgatacgtt
     9181 gatcgcacca tttagagctg tcccaagttt gggaaccaac gtggcaaaac aaatcgttga
     9241 agcaagaaaa gacggtccat ttttatccaa agaagatctt gccacccgcg gtaaagtttc
     9301 aaaaacattg atcgaatata tgaacgacaa tggcgtattg aaagatctac cagatgaaaa
     9361 tcaattatcg ttattcgata tgctataagc atctgttttc ctgtctgctt gtaattttaa
     9421 gcagagtatg gtatagttct tataggtaat gatactaact gtgagtgagc ggatttttcg
     9481 ctcactcttt ttaatggaat tacgcactta attttttaag gaggcgaaac ttttgagtag
     9541 cgtcgttgaa acagtcacag aaatggtgac accgatttta gatgaacaaa attttgaact
     9601 tgtcgaagtc gaatttgtaa aagaaggaaa aagctggttc ttacgagtat ttattgacaa
     9661 agaaggcggt atcgatatcg aagaatgcgc ctttgtcagt gagaaactga gtgaaaaact
     9721 tgatgcagca gatccagatc cgattcctca agcctatttc ctggaggtat cctccccggg
     9781 agcagagcgg ccattgaaaa aagaaagcga ctatgaaaag gcacttggtg attatgtcca
     9841 tgtctcctta taccaaccag tagatggcga aaaacaatat gaaggatttc ttcaatcatt
     9901 tgatgctgaa cagcttacat tgaaaatacg cataaaaaca cgagaaaaag aattgacttt
     9961 tgaccgaaaa aatattgcaa aagctcgctt agctatccaa ttttaatcac ggagaggaat
    10021 cagaaaaaat gagtaaagaa atgttaaatg cgttagacgc tttagaagct gaaaaaggga
    10081 tctcaaaaga aatcgtgatc gatgctttag aagcagcatt ggtttctgca tacaaacgtc
    10141 actatggcca agcacaaaac gtcgaagtgg aatttgatca gaaaaaagga aagatccatg
    10201 tctatgcggt aaaagaagta acggaagaag tgatggattc acagttggaa gtctcattga
    10261 aagatgcact tttaatcaat ccagcatatg agatcggtga tacgatccgt tttgaagtaa
    10321 caccaaaaga ttttgggcgg atcgctgcgc aaacggctaa acaagttatt ttacagcgtg
    10381 tacgtgaagc agaaagaacg attatttata acgaattcag tgcttatgaa aaagacatca
    10441 tgcaaggaat cgtcgaacgc caggataaac gttatattta tgtcaatctt ggtaaaattg
    10501 aggcagttct ttctaaacaa gatcaaatgc caaatgaatt ttatcaacca catgatcgaa
    10561 tcaaagttta tgtttcccga gtagaaaata cgtctaaagg tccgcaagta tttgttagcc
    10621 gcagccatcc agacctattg cgccgcttat ttgagcaaga agtaccagaa gtctatgatg
    10681 gaatcgttga aattgtcagc atcgcccgtg aagctggcga tcgttcaaaa gtggcagttc
    10741 gctcaaatga tccaaatatc gatgcagtcg gtacatgtgt cgggccaaag ggacaacgag
    10801 ttcaagcaat cgtcaatgaa ttaaaaggcg aaaacatgga tatcgtcgaa tggaatgaag
    10861 atccagctgt attcattgca aatgcattga atcctgcaca agtcatggat gtgatcttcg
    10921 atgagacaaa tccaaaggcc tgcacagttg tcgttccaga ctaccaatta tcgctagcaa
    10981 tcggtaaacg cggacaaaac gcacgtttag ctgctaaatt gactaaccat aaaatcgata
    11041 tcaaatcaga atctgacatg acggaatttt atgaaaatca agaacaacaa aaagaaacag
    11101 aagaactgca tgatgaagca atcgttcagt cagatttaac agacgatgaa tatgaaacaa
    11161 ttgcattcaa caatgaaacg gtcgaagaaa aaccagaagc ttaactttag taaggaggca
    11221 aagagatgaa acaaaggaaa attcctttac gcaaatccgt ggtttcaggt gaaatgaaac
    11281 ctaaaaaaga gatggtccga atcacccgtt caaaagaagg ggaagtatcg atcgatccaa
    11341 ctggaaaaat gcctggacga ggagcgtatg tctcacttga gccggaagaa gtacaacaag
    11401 cttgggataa aaaaattctc gatcgagtac tcgaaacaac attaacagat gagttttatc
    11461 aagaacttct tgactatgtc actcaccaaa aagcacgtaa agagttattt ggaaaatgaa
    11521 tacagttaat cggcaagaag ccatgaatct catcggtcta gcgatgcgcg cgggaaaact
    11581 aatcacgggt gaagaactga ccattgctga aatccgcaaa caaaaagcaa aattggtgtt
    11641 tgtggcaacc gatgcaagcg agaatacaag aaaaaagata aaagataaga gttcatatta
    11701 tgaagttcct tgctttgagc tattttctga agcagaaatc acgcagatga tcggaaaacc
    11761 tcgcaaggta ttcggaataa tggatgccgg atttgcgaag aagaccaagg agctaattga
    11821 aggttaggaa ggtgattgca tgggcaacaa aagaatctat gaattagcaa aagaactcaa
    11881 aaaatctagt aaagacgtcg tggaaaaagc acaacaactt ggcatcgatg tgaaaaacca
    11941 tatgggtgcg attactagca atgatgagaa gaaattgcaa caagcgttca aaaacccaag
    12001 cacgaaacaa caagctgcac aacaagcaag cagaaaacca gccaatcaac agccgaacga
    12061 tcaacgtaaa aaagaaacaa cgaacaatca acaaaaaaat aaaaataacc gcagttatca
    12121 agatcgcggt caagggagcg gtcaagtgaa tcaaggaaaa aaaccaacaa caaacccaaa
    12181 taatacggga aataccagca gccaaaatcg tcaaggaacg agccaaggcg gcaatcaaaa
    12241 ccgtactaac aataacaaca aaccaaacaa taacaatcgc ggcaaattta ataataataa
    12301 ccgtaatcgt tataataaaa aaggtaaaaa aggcaaacag caacaatcaa ctaaaccagc
    12361 tgtaccacca cgcaaattcc gtgaattgcc agatgtatta gagtatactg aaggtatgaa
    12421 cgtagcagat attgcgaaaa aaattcatcg tgagccagca gaaatcatta aaaaattatt
    12481 tatgcttggt gtcatggtca atcaaaacca agcactggat aaagatacga ttgaactgtt
    12541 agcgacggac tatggcatgg aaccacaaga aaaagtccaa gttgacattg ctgatatcga
    12601 taaattcttc gaggcagaag aagtcgatcc agataaatta gtctcacgtc cgccagtcgt
    12661 aacgattatg ggacacgtag accatgggaa aacaacttta ttggatacat tacgccattc
    12721 acgtgtaaca agcggcgaag ccggcggaat cacacagcat atcggtgcct accagatcga
    12781 tattgatggt aaaccaatca ctttcttgga tacaccagga catgcggcct ttacaagtat
    12841 gcgtgcacgt ggagcaagta tcacagatat cacgatctta gttgttgctg cagatgatgg
    12901 cgtcatgcca caaacagttg aagcaatcaa ccatgccaaa gctgcaggcg ttccaatcat
    12961 cgtcgctgta aataaaattg ataaaccagg tgcaaaccct caacatgtta tgcaagaatt
    13021 aagtgagtat gagttaattc ctgaagcatg gggtggagaa acgatctttg ttgagatctc
    13081 agcgaaattc ggccaaaaca tcgaagaatt gctggaaatg atcctgttag tcgcagaagt
    13141 agaagattta aaagcagatc caacacaacg cgcaatcgga acagtgatcg aagcacgtct
    13201 tgataaaggt aaaggtcctg tgtcaacctt acttgtccaa gaaggaacac ttcatgttgg
    13261 tgacccaatc gttgtcggta atacttacgg acgtgtccgt gtaatgacaa acgatcttgg
    13321 ccgtcgcgat aaagaagcag gacctgcaac gccagtagaa atcactggct tgaatgatgt
    13381 acctcaagca ggtgaccgtt tcgtagtctt cgaagacgaa aagacagcac gtgcagcggg
    13441 tgaagaacgc gcgaaacgtg cattattaga aaaccgtgct gccacaagcc gtgtgacttt
    13501 ggataactta tttgaaagcc tgaaagaagg cgaattgaaa gaagttaacg taatcatcaa
    13561 agcagatgta caaggttcag cagaagcact ggctgcatca ttgaagaaga ttgatgtgga
    13621 aggtgtccgt gtaaaaatcg tccattcagc tgtcggagca atcaatgaaa gtgatgtaac
    13681 cttagcagca gccagcaacg ctattatcat cggtttcaac gttcgtccta caccgcaggc
    13741 aaaagtgcaa gctgatactg aagaagtcga tattcgtctt caccgtatca tctataaagc
    13801 catcgaagaa atcgaaactg cgatgaaagg gatgctagac cctgaatttg aagaaaaaat
    13861 caccggtcaa atgatcgttc gtgaaacctt caaagtttct aaagttggta cgattgcagg
    13921 tgcctatgta acagaaggat atattcgtag agatagcggt gtccgtgtaa tccgtgacgg
    13981 aatcgtaatc tatgaaggcc aacttgcaag tctgaaacga ttcaaagatg acgtgaaaga
    14041 agtcaaaatg ggttatgaat gtggtgcaat gattgaaaaa ttcaatgaca tcaaagtaga
    14101 tgacgtaatt gaaggattta tcatggaaga agtcaaaaat gactaaaaac tgataaaagg
    14161 aggccaatca ttatggctaa ctaccgtgac cgccgagtcg gtcaagaaat cttaaaagaa
    14221 gtcaatgata ttttgcgcaa aaaggtccgt gaccctcgtg tggagaacgt aacgatcaca
    14281 gatgtgaaag ttacggggga cttacagcaa gcaacgatct attacagcat tttatctgac
    14341 ttagcatcag ataagaaaac agcacaagat ggattgaata aagcatcagg attgattcgt
    14401 cgagagttag ggcacaatct aagtatttat aagacacctg aattgttctt tgaacttgat
    14461 gaatcagttg tctatggcaa ccatatcgat gaattgcttc gcgacttgaa caaagactaa
    14521 tcaaaaactc ccgcaaatcc tgtgaaatca ggggttgcgg gatttttttg ttttcattaa
    14581 gacgtattac ctaagagttc catgacttta gtcttgcggc gtgtcagcta accaaaaaag
    14641 agaaaaagaa aagtaaaaaa ttcgactttc ttttttctag tagtatataa atttttgcat
    14701 atagataaag atcaagatac cgataacgga agctagattg taatctattt tagtgacagt
    14761 caggtatagc caagtaacta gaagatcagt ggaacctgca ccataaaagt ttgagtttgt
    14821 cggtccgttg acagttaaaa gaaaaatcac gttgaagtta ttgatatttc cgattacgcc
    14881 gcttcgattt ggtcacgatc caaattttgg ataatccctg tagaaattag catagtagct
    14941 gggataccaa ttcacatatt gacaaagata acagagactt ttacataaaa cggatcaatc
    15001 aggaaaggaa ttgctcgatc cagccccagt tttccagcaa tgtgttaact ggcccagcgt
    15061 cattcagcaa attatgcatg atgaggagcg aaatgaactg cggaacagcc attgtgataa
    15121 cgacaagttt tttggatcaa tgtaaaaaac gtcagcgaaa ggaaaaattt cgtggttttt
    15181 tatacctgtt catttggcta gatataaaat ccaaacaaat gaacagaagt gcttattagg
    15241 tttcaattgg gagtatctgc gctagaataa gagtaataat gaaaaggagt gttatgtatg
    15301 gattattcta gtaaagaata ctttgataaa atgacggctt ggtggcgtgc tgctaattat
    15361 ctttctgttg ggcaacttta tcttaaagat aaccccttac tgagacgtac actgaaaccc
    15421 gaagatgtca aaaaacatcc aatcggtcat tggggaacga ttcctggcca aaattttatt
    15481 tatgtccatt tgaaccgagt catcaataaa tatgatttga acatgtttta tattgaaggg
    15541 ccaggacacg gcggacaagt catggtatcg aatgcttatt tagatggaag ttacacagag
    15601 atctatccag aagtaacgga agatgagaca ggaatgcaaa aattattcaa acgattttca
    15661 tttcctggag gcattgcttc tcatgcagca ccagaaacac caggttctat ccatgaaggc
    15721 ggagagcttg gatactctct ttcacatgca gtcggagctg tattagacaa tcctgaagta
    15781 atctctgctg tcgtgattgg tgatggtgaa gcggaaaccg gtcctttagc tggaagctgg
    15841 ttctcaaatg tctttatcaa tccagtgata gatggagctg ttttaccgat ccttcattta
    15901 aatggtgcaa aaatagccaa cccaacgatc ttggcacgta aatcagatgg agaattagca
    15961 aattacttta acggacttgg ctgggaacct ttctttattg aaggaaatga ttcagaaaaa
    16021 ttaaatcctg ttatggctga aaaaatggat caagcaatcg agaaaattaa atccatccaa
    16081 aaagaagctc gcctgaagac agcaacagat gtcgtgatgc caaaatggcc agtattgatc
    16141 gtacgcacac caaaaggatg gaccggtcca aaagaatggg acggggaacc aattgaagga
    16201 accttccgag cacaccaagt accgattcct gtagatcaag aacatatgga tcatgcagat
    16261 gctttactcc gttggctgaa atcctatgaa ccagaaaaat tatttgatgc acaaggacgt
    16321 attttagaag aaatcagaga aatcgcgcct actggtgacc aaagaatggc aaaaaatcct
    16381 atcaccaatg gtggaatcga tccaagaccg cttattatgc cagattggaa aaaatatact
    16441 ttgcaatttg aaaaaccagg ctccgttaaa gcagaagata tgaccgaact tggtaaattc
    16501 gttcgcgaga tcattgagaa aaatccagaa aatttccgta tatttggacc agatgaaaca
    16561 aaatcaaacc gattgaatca agttttcaaa acgacaaatc gccaatggat ggaaaaaatc
    16621 gaaccagaaa atgatgaatg gctttcgcca tctggtcgcg tcatcgacag tcaattatcg
    16681 gaacaccaag atgaagggtt cttagaaggg tacgttctga ctggacggca tggttttttg
    16741 caagttacga atcattcttg cgagtggttg actctatgtt gactcagcac ttcaaatgga
    16801 tgcggaaatc acatgacctt tcttggcgaa atgattatcc ttcgctaaat ctcattgcaa
    16861 gctcaacagt cttccagcaa gatcacaatg gatatagcca ccaagatcca ggaatattga
    16921 cacatttggc agaaaagaag gcggagttca tccgtgaata tctgcctgcg gatgcaaata
    16981 cattgctcgc agtcatggat aaagcattcc gctcgtcaga aaaaatcaat ttgatcatct
    17041 cttccaaaca tccgcgtgct caattttact cagcagaaga agcagccgtc ttagtgaatg
    17101 aaggcttgaa aatcattgat tgggcttcga cagcaaaaga ggaggaacct gaattggtca
    17161 ttgctgctgc aggaacggaa tctaacttag aagcattagc agctgtaact ttgctgctgg
    17221 aagaattccc aaaactaaaa attcggttca tcaatgtcgt agatttattg aaattacgtc
    17281 atccaagtca agatccgcgt gggttgagcg atgaagaatt tgatcaatat tttacaaaag
    17341 acaaaccgat cttatttgct ttccacggtt atgaaacatt ggtccgcacg attttctttg
    17401 atcgtcataa ccatcattta atgattcatg gctacaaaga aaatggagat atcacgacac
    17461 catttgacat gcgtgtagta aatgaacttg atcgttatca tttggcaaaa gacgcagctt
    17521 taaaaatcaa aggaagtcaa gcagaagatt ttgcgaaaaa aatggatcag aaattacaag
    17581 aacatcaaaa ctatattcgt gaaaatggta ttgatctgcc agaagtattg gattggaaat
    17641 ggaaaaatct tgaccaataa aatgataaaa tcgatcccgc aaaatagaat tttttacatt
    17701 gattaagaaa ctgaaaaaat aaataaaaaa aacggaaaaa agactggaag aatggccagt
    17761 cttttttttc gtttttggga agtgaaaacc aaactattta cctgtaagcc acccataaat
    17821 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaagcataa
    17881 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
    17941 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
    18001 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat tacctttatg gaaagaacgc
    18061 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
    18121 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
    18181 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
    18241 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
    18301 gatatgtctt tatctgaaaa aaaaatagat gaagtgatgg cttcatttat tggtgagatc
    18361 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
    18421 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
    18481 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
    18541 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
    18601 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaggat
    18661 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
    18721 ctgccaatag aaaaaggagt ggaacggttc aaacgagtag atattactga tgaagtatgg
    18781 cagaaagtaa aaaacggtat gagacttgat tatactgtat ttgcgctccc agaaatgccg
    18841 tcagaagaaa ttgctttgtt ttataaagga aaagttgtca gtatttatca gccaaacccg
    18901 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
    18961 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
    19021 gtgctgggat ttttcgacgg cgtgcatatc ggacaccaga aagtcataaa gacaggtatg
    19081 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatct
    19141 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
    19201 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
    19261 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
    19321 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
    19381 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
    19441 ggtgaaaaaa tcagctctac ccgtattcgt ggattactag acagcggaca agtaaaagaa
    19501 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
    19561 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac ggttcatttg
    19621 cctaaagaag gtgtttatgt gtcggaaata aaaattgggg aaacatggta tccagccatg
    19681 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agagttgtat
    19741 attttggact ttaatcaaga tatctatggt gaacatgtcg cggtacgctg gaatcaattt
    19801 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaggaggat
    19861 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
    19921 ttatgtataa ctagcaatta caataaaatg ggtgataaat aagcccagga aaggggctgt
    19981 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
    20041 cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct ttctttatag
    20101 aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat ttgctttaga
    20161 ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg taataacagg
    20221 tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa agtcgcagta
    20281 gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg gaaagaaaaa
    20341 atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc agtcaaagca
    20401 atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc tgaagaagga
    20461 atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt ttgggttaat
    20521 aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga ttgggaaaga
    20581 gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt aaattacttt
    20641 acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga acagatccca
    20701 tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt taccgaaacg
    20761 gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc tggtgctatc
    20821 cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact cttggaaagt
    20881 atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc tgcatggttg
    20941 gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg tgggatgact
    21001 ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg tttattgatt
    21061 gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa gattggtggc
    21121 agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg cttactcgtt
    21181 caattattcg cttctccagc tggtatttca gtgactacat ttttgattag tttactttct
    21241 ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt gattggtgtt
    21301 tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt gattggtgtc
    21361 ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc agcaatcatt
    21421 cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa aaaaggcggt
    21481 atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt atacagtgca
    21541 ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat gatcggtgtc
    21601 tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc tgaagacaag
    21661 agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc ttatattttt
    21721 tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa cgtagttatc
    21781 tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga aaaaaaatta
    21841 acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt tatttgagga
    21901 taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac agtaagtact
    21961 tataaaaaa
//
LOCUS       DAXLPQ010000045        21185 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.045, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000045 DAXLPQ010000000
VERSION     DAXLPQ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.045"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(565..1590)
                     /locus_tag="ACF3UO_001990"
     CDS             complement(565..1590)
                     /locus_tag="ACF3UO_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3657977.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1865..3550
                     /locus_tag="ACF3UO_001991"
     CDS             1865..3550
                     /locus_tag="ACF3UO_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFD3657978.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3564..4847
                     /locus_tag="ACF3UO_001992"
     CDS             3564..4847
                     /locus_tag="ACF3UO_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3657979.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4917..5786
                     /locus_tag="ACF3UO_001993"
     CDS             4917..5786
                     /locus_tag="ACF3UO_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657980.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5783..6619
                     /locus_tag="ACF3UO_001994"
     CDS             5783..6619
                     /locus_tag="ACF3UO_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3657981.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KVRSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6645..7712
                     /locus_tag="ACF3UO_001995"
     CDS             6645..7712
                     /locus_tag="ACF3UO_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFD3657982.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7709..8536
                     /locus_tag="ACF3UO_001996"
     CDS             7709..8536
                     /locus_tag="ACF3UO_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFD3657983.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8581..9606
                     /locus_tag="ACF3UO_001997"
     CDS             8581..9606
                     /locus_tag="ACF3UO_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3657984.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9603..11786
                     /locus_tag="ACF3UO_001998"
     CDS             9603..11786
                     /locus_tag="ACF3UO_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFD3657985.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11786..12916
                     /locus_tag="ACF3UO_001999"
     CDS             11786..12916
                     /locus_tag="ACF3UO_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3657986.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12913..13590
                     /gene="pgmB"
                     /locus_tag="ACF3UO_002000"
     CDS             12913..13590
                     /gene="pgmB"
                     /locus_tag="ACF3UO_002000"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFD3657987.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13674..14201
                     /gene="msrA"
                     /locus_tag="ACF3UO_002001"
     CDS             13674..14201
                     /gene="msrA"
                     /locus_tag="ACF3UO_002001"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFD3657988.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14402..15088)
                     /locus_tag="ACF3UO_002002"
     CDS             complement(14402..15088)
                     /locus_tag="ACF3UO_002002"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFD3657989.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15168..16706
                     /locus_tag="ACF3UO_002003"
     CDS             15168..16706
                     /locus_tag="ACF3UO_002003"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFD3657990.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16826..17293
                     /locus_tag="ACF3UO_002004"
     CDS             16826..17293
                     /locus_tag="ACF3UO_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFD3657991.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17827..18255
                     /gene="rplM"
                     /locus_tag="ACF3UO_002005"
     CDS             17827..18255
                     /gene="rplM"
                     /locus_tag="ACF3UO_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFD3657992.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18271..18663
                     /gene="rpsI"
                     /locus_tag="ACF3UO_002006"
     CDS             18271..18663
                     /gene="rpsI"
                     /locus_tag="ACF3UO_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFD3657993.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18751..19977)
                     /locus_tag="ACF3UO_002007"
     CDS             complement(18751..19977)
                     /locus_tag="ACF3UO_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3657994.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(20049..20351)
                     /locus_tag="ACF3UO_002008"
     CDS             complement(20049..20351)
                     /locus_tag="ACF3UO_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3657995.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            20899..>21185
                     /locus_tag="ACF3UO_002009"
     CDS             20899..>21185
                     /locus_tag="ACF3UO_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3657996.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGT"
BASE COUNT         6860 a         3780 c         4391 g         6154 t
ORIGIN      
        1 ttgtcacaac ctcttttttg gtttgtctaa aataatttgt ctaactagaa gaaaagtggg
       61 aaaggatctt aacaacatcg gttcgtatcc aattaaggta tcggaacgat catcttccaa
      121 gagaagtcaa tcaacaaaag taaagataga tcattttttg aatgcaaaat aaattgatgg
      181 gaagatagag cggttatttt taatattttg ctagctatta ttgaataatt cctcgaataa
      241 aacaaaacca gtagacatgt ctgttattct atttatgttt tagagataag tatccccaaa
      301 taacatggat tgaaataagg gtaaatgtgt ttaaaaaaac gaactataaa aacttataca
      361 caacgtggtt aaaaatagtt ttttcttccc tgtggaaaaa atagtttaac acaaacatta
      421 tagttatcca cagctatcta aaacagatgg aaaataagaa aaattcgcta aaataccggg
      481 agggggtaac gagggatgag tgattgaaaa aagaacagag taactgactt atcctcagtg
      541 tttctgttct tttataattc tgttctacat ttcttgttgt tggatcgaat ctgtgagagt
      601 aatctcggtt gaaagaatga ttcttttttc ttcagggtat tggtggtgga ttagttggaa
      661 taaaagttct gtggctttga ttcctaactg atttgtcgga atgtctatcc gagtcaactg
      721 tggcgaaaat agggaggaca ataagggatc actgaatcct gcgatcgaaa gatcatcagg
      781 tatctgcttt ccagattgtt ctgccacttt gtaaatactc aatgatttta atgcatcggt
      841 agaaaaaatc gcagttggtc tttctcgtag cttcattaaa tcattcattg ctgccatgct
      901 atcttctaag cgaaagccgc cgtctataat ccattcatta cggatatcta ggtggtgatc
      961 aaataagcat tgacggtaac cattgagacg atcattggat acataaactt ctgtcggagc
     1021 atggagacag ccgatatgac ggtgtccatt cttgatcagt gtttccacca aatcgtaact
     1081 atcctggaaa ttatccgtgt ccactgagta gatgttcgtg tagtcgtttc cgacttttcc
     1141 gattaccaca ataggaatat tgtattgatc caattcaaaa agaagtgttt catccatcgt
     1201 agagcttaaa ataataattc ctcggatcat tttttcttgg atctttttcg cgcatttttc
     1261 tagctcttct tctggtgttt ttgccgtttg tagaatcaag tcgaagttat tttgttcaga
     1321 aacggcagaa atggattgaa taacatctga aaaaaaagga ttgccatagg tcgtatgaga
     1381 agtacgatga gataatgcta gaatcgcgtc aaaaccattt cctgacagtc ctcttgcaat
     1441 tttgctcggt tcataattca attctttgat tgcttgaagt acacttgctt ttgctttatc
     1501 agagatattt ggctggttat ttaatactct ggagacagtt gattttgaga cattagcttt
     1561 tttcgcaatg tcataaatag taggtttcaa ttttatatgc acctcctttt tgggagcgtt
     1621 ttagaataat tccatagtac aatagacatt cttttttgtc tatgattttg aaaatttagg
     1681 aatagcttgc atgatcatga gagaccatat ttttttaaga agctattaat tattgataca
     1741 taagctttct tatttgtatt tttgtgtata tcaaaattat ttaaaaaaat gctattgaca
     1801 gtaagcgttt tccataatat gatcaaatcg ttgggaacgc tcccaaaaaa gaaaggggaa
     1861 tccgatgtat acaaaacttt tacaagcgat ttatcgcgac tcagatttgt ctgagaaaac
     1921 cgcctctatg attgaacaaa aagtcagtgt ttatcagcag aagaaaggcc aggcaggcaa
     1981 actgcattgg gacgaagaag atattttctt gattacttat ggggatcaat tttttgaaga
     2041 gcagcaacca actttgcgta catttaagaa attttatcaa aagtatttgg cagatacatt
     2101 tagagttgta catttcttgc catttttccc atatacatct gatgatggtt tctccgttgt
     2161 aaattatcag gcaatcaacg accgtttggg cacatgggaa gatatagaag aaatgagaag
     2221 cgaaacacgg ttaatgttcg actttgtctg caatcatatg tctgccgaaa gtacttggtt
     2281 tcaggaatat ttaaacttga atgatacgta caaagatttt tttattgatt tgccactgga
     2341 tacagataca agcagcgtga ctagaccaag gaccagcccg ttacttacaa cgttcattga
     2401 caaaaacggg aaagaaaaac acgtatggac gacttttagc gaagatcaag tagacttgaa
     2461 ttttaaaaat ccagaagttt tattgaaaat gatcgatatt cttttgtttt acttagaaaa
     2521 aggcgcttca tttattcgct tggacgctgt gggattttta tggaaagaac taggaacttc
     2581 ttgtatacac ctgccagaaa cgcataaaat catccaatta ttccgtgcaa tcgctgatga
     2641 agcagctcca ggaacggtat tgatcactga gacaaatgtg ccacacaaag ataatatcag
     2701 ttattttggg aatggcgaga atgaagcaca gatggtctat cagttttcgc taccaccttt
     2761 gacccttcaa gcgattcgtt cgggtaatac aagtaagttg aaagaatggt taaaaaccat
     2821 cgatttcgca tcgaaaaaaa caactttttt taatttttta gcctcccatg acggtatcgg
     2881 attgaatccg gtacgaggta ttctgccgga aaaaacgatc cttgaattag tggaacagct
     2941 gaagaaagag ggtgcccgag taaactacaa gaaaaaccca gatggaacga ccagtccata
     3001 tgagataaac gctacgtatc tagatgcgtt aagttctcca acagatacga cggaatggag
     3061 aagcaaacgc tttttagctg ctcattcatt tttggtaacg ttaccaggcg tgccggcaat
     3121 ttatattcaa agtgtgctgg gaagtcgaaa tgattacaaa ggcgtagaaa aaacaggaga
     3181 gaatcgaaaa atcaatcggc aaaaattttt gttagcagat attgagaaag agttgcagac
     3241 agatccatta agaacagcag tatatggtga attgacccag atgctatcta ttcgaaaaaa
     3301 agaaaaagcc ttccatccga atagtttgat ttacttactg gactcagcag attcttttat
     3361 cagttttatt cgcgaagcga aggaagagaa agtcttagtt atccataatt tttccaatca
     3421 atcagcaggt tatcttttac caaaaggaga ttacctagac ctgttttctg gacaaattat
     3481 ccattgcagt caagaacgaa agttgatatt ccagccgtat gaatatatgt ggctgaaaat
     3541 aataaaataa gaggtggaaa aaaatgaaaa aaattattgt tactacctgt ctgctagcta
     3601 ctggatttct tcttactgct tgtggtgaaa gtcaaagctc taacgaatca caacagacaa
     3661 cgattcaatt catgcactct tctgtcgaac aggaacgatt aagtgtgatc aatgaactgg
     3721 ttgctgattt tgaaaaagaa aatccagaca tcaaaatcaa gcaagtgccg gtagaagaat
     3781 cagcgttcaa tacaaaaatc gttacgttag ctcgttccgg taaattacca gaagtaatgg
     3841 aagtcagtca ggattttgct aaagtgatgg ataaagatga actgattgat cagacggcag
     3901 tccaaaacgt tatcgaggaa gctggagaag ataattatta tgacggagcc aaaaaccttg
     3961 ttcgttcaga agatggaaaa agctatattg ctgcaccaat tagcggctgg gttcaaggta
     4021 tttggtatga caaagaaaaa ttatcagaag ctggtttttc agaaccagaa aattgggatg
     4081 atattttaaa aattgctcaa catttcacag ataaagagaa taaacaatat ggaattgcta
     4141 tgcctactgc tgaaggaaca atgagtgagc aagcgttctc tcaatttgct ttgtcaaatg
     4201 gagcaaatgt tttggatgat gaaggcgagg taacgatcga tacggaaaag atgagagaag
     4261 cattgtcgtt ttatcaaaac ttatcccaat acacgatgcc aggctctaat gatgtgacag
     4321 aaatcaaaga tgctttcatg aatggaacag caccaatggc aatctattca acttacattt
     4381 tgccttctgt ttatgaagcg gggaactcag aaaatatcgg ttttgctatc ccaacacaaa
     4441 aagatcaagc tgtctatggc acagtatctg gattgacgat ttcttctggt ctagacgaga
     4501 aacaaaaaga ggctgctgaa gcattcacag ctttcttatc tcaaccgaaa aacatggaaa
     4561 agtgggtctt gatgtctcct ggtggtgctc aaccagtgaa taaacaagta gtcgaactgg
     4621 atggttacaa agaaaatgaa gtcatcaagt cttttggcga gctgccatct gagattgcta
     4681 gtgcttttga tgaagtacaa gtctttggac tagtcgggga aaagaatttc acgaaaatgg
     4741 gagatatcac aagctcaggt gtgatcggaa aagcagtgaa ccaagtaact gtcggaaacg
     4801 aagatgtcga tcaagcttta gctgacgcac aaaaaaatac gaaataacaa gaagttctgc
     4861 caatggtgtt cgaaaaaagt agatagctat tggcagatta tcagggggag gtttcaatga
     4921 atcgtccaag gaaacattct gacttaaaat tagccatggg acttttagca ccaagcatgc
     4981 ttttattagc tgttttagtg ctgattccaa tgctttccaa tattcagatc agttttttcg
     5041 atatgccgct gaatcctaac tcagacgccg tttttatcgg attaagcaat tatcttgaaa
     5101 ttttaagtga tagtgaattt tatcgttctt taggtttaac agttgcttac acattcttag
     5161 ttgtagcagg cagtacagct ttaggattag ccgtagctat tttgcttaac cgcaagttca
     5221 gatttaggaa aacggtgcgt tcactgattt tattaagtta tgttacgcca tctatttctt
     5281 tgatttttgc ttggaaatat atgttcaata atagttatgg aatcgtcaat gatctgttag
     5341 tagataggtt gcagcttttc aacgaagcac cgctgtggtt cgaccagcca gttgctagct
     5401 tctttatggt cgttttgttt gctatctgga gatactatcc gtatgcgttt atttcatttt
     5461 tggctatttt gcaaacagtc gacaaaacgc tttatgaagc agctgaaatg gacggtgcaa
     5521 atgcttggca gaagttcaag atcgtgacac tgccggcaat caaaccagta ctagcaactg
     5581 tgattgtttt acgatctatc tggatgttct atatgtttac agatgtctat ctactgacga
     5641 ataaagtcaa tatcttaggc gtttatttgt atcagacagc ctttgcgttc aatgatcttg
     5701 gaaaagcagc agctatatcg attctattgt tcatcattat tgcagcggtc gtcttgctct
     5761 cacgaaagaa ggtggacttg aaatgaaaaa taaaaagagc aggaaaatct tattttacgc
     5821 gacgattttg ttgctattag ctgtcaattt gtttccattt ttgatcatgc tgatgacatc
     5881 attcaaggat tcacaagaag caattgcaac gacacaaact atttttccga aagaatggac
     5941 ttttgaacat tatcaggata ttttcaatgc tgagattttt ccattcatca tgtatttcaa
     6001 aaatagttta gtgatctcct tgatagcctc cgtaactgca gtagtgattg ggatcagcgg
     6061 ggcatacgct ttgtcaaaac tacgcttcaa agttcgctcg aaaatcaatg ctagctttta
     6121 caccgtttat atgttttccg gtattttgat cgttgttcca ttatttaaaa tcatttccgg
     6181 tctaggtttg tatgatacca atacagcact gattatcacg atggtcgttc aaacacttcc
     6241 tactgcgata ttcatgctaa aaagttattt tgacacgatt ccgactgata ttgaagaagc
     6301 agcaatgatc gatggtctta gccggatcca gatcattatt cggatcatta taccattggc
     6361 tatttctgga atcatttctg tcttcgttta ttgctttatg gtttcgtgga atgattattt
     6421 atttgcttcg attttcctgt cgacctccga aaaatttact ttaccaatcg gtttgaacac
     6481 attattcagt acaccagact acatttgggg acgaatgatg gccgcttcat tggtgaccgc
     6541 tttaccagtc atcattatgt atgcgttatc tgaacgattt attaaaggtg atttagtcga
     6601 aggcggcgta aaaggataaa aagaaaagaa agaggaaaga aaagatgaaa aaattagttg
     6661 cattagaacc aagaatagcc ggattcaaag attacgaaga ccgtgagatc gaaaagaacg
     6721 aagtacgtat ccgagtaatt ttcgctactc caaaaccagg aacagaaatt gtcgacttta
     6781 gaggattaag tccatttatc gatgaagaat tttcagaaga atggcgccta ttcttgccaa
     6841 gagaagaagg aagccaacgc ggtgtggtat ttggcgaatt tcaattagga aatatgattg
     6901 tcggtacgat cgaagaaacg ggcagtttgg tgacagagta tcaaaaagga gagttagtct
     6961 gcacttatgg acccattcgt gaaacgctga ttacaaacgg tgttgataat tataaactac
     7021 gtaaacttga tcggttggat caatggaaaa atgcagtatg ttacgatcct gctcaattcg
     7081 ctttaggtgg tatccgggaa gcacatgttc gagcaggtga tgctgtagca atcttcggtt
     7141 taggcgctat cgggcaaatt gcgattcaat tagctaaaaa agcaggtgct actaccatcg
     7201 ttgggatcga tcccatagcg cagcgtagag aattagcaga aaaatacggt gccgattaca
     7261 cgctagatcc tatgaaagca gatgtcggtt ttcgtctaaa ggaattgaca gataaacgtg
     7321 gagtagattc agttattgaa acgagtggca gtgctgccgc attacaagct tctttaagag
     7381 ggatcggcta tggcgggatc atttcttatg ttgcctttgc taaacctttt ccagctgggt
     7441 ttaatcttgg tcgcgaagca catttcaata atgcaaaaat cgtctttgct cgagcatcta
     7501 gtgaaccaaa cccagattac ccaagatgga accgtaaacg aatcgaggac acatgttggg
     7561 aattattgat gaacggttac ttggattgtg aagaaatcat tgatccagtt gtgccatttg
     7621 cagaaagcgc agaagcttac atgcgttatg tagaccagca cccagaagaa agtatcaaaa
     7681 tgggcgttca agtccgagga ggagaacaat gaaattcggt acgcaagatc aagcattttt
     7741 cccaagagac attttagaaa aatttagatt tatcaaagac tgtggatttg aagaatacga
     7801 aatcgacggt aagttgttaa tagaaaatat cgacacagtc aaacaggcaa tcaaagaaac
     7861 agggatccca gtagtgacag cttgtaacgg ctacgatggg tggatcggtg actttatcga
     7921 agaacggcgt cttaatggtg tacgtcaaat tgctgagatt ttgcgtgcac taagcgaggt
     7981 tggaggcaaa ggaatcgtta tcccagcagc ttggggaatg ttcacttatc gattaccgcc
     8041 gatggtttca ccccgaagca aagaaggaga ctataaagca gtcagcgaat cacttcgtta
     8101 tttagataaa gtagccgaag aaacaggtac ggttatttat ttggagcctt tgaaccgata
     8161 ccaagaccat atgatcaatt tgttagcgga tgcgcgtcat tacattgact ctaatcaatt
     8221 gaaacatgtg cagatcatcg ctgattttta tcatatgaat attgaagaag atgatatttc
     8281 aaaagcattg actacgcaaa aagagtatgt gggtcatatc catttagcag ataatcatcg
     8341 ctaccaacca ggatctggcg caattgattt tactcgccat tttcaaacgc tacttcaaaa
     8401 tgagtatgaa ggttatatgg tatatgaatg tcgtttgcga ggagaaaatg aagtgaaaat
     8461 ttatcaggaa tcattgcaat acttgaaaaa ctgtctggaa acagcgcgtc atttaaatga
     8521 tttagagaaa gaatagagaa agaataacaa taagtaaata agcaaaggag ggagaaataa
     8581 atgaagaaag tagcaatcat aggcgctgga caagtagcag aaaaagtaca tgctgcttat
     8641 tatcaaaaaa gatcagatgt cttagaattg gccgctgtgg ttgatccagt cagccagcga
     8701 gcagaagact tttgccgacg tacaggattt tctcatgcgt atacatcagt tacacaaatg
     8761 ctgaatgaga tttctcccga tatcgtgagt gtctgtacac ccaatcgctt tcacttcgaa
     8821 catgtattgg ctgccctcga agctaatgct tcagtgatgt gcgagaaacc accagctatg
     8881 acagctgatc aagcaagaaa gatggcagag acagccgata aaaacgggca gattttggct
     8941 tatggattcc agcatcgttt ttctgacgaa gcaacaatga tcaagaatca tcttgatgtt
     9001 ctcggggata tttattacgt agaagcgaat gcgcttcgtc ggtctggtgt tccaggctgg
     9061 ggaacgttta tcgacaaaga acttcaagga ggcgggcctt tgatcgatta tggcattcac
     9121 atgcttgata cagcgatgta tattactgga tttcctaaag taaaaagcgt tcgggcgtac
     9181 agcttccaaa aaattggtac gaaaaaaaat tcagggaaat tcgggaaatg ggatccaagc
     9241 aaattcacag tagaagatgc aatttttggc acactggaat tagaaaacgg caagatcatc
     9301 caactgaata cttcgtttgc tttgaatatc agagaagaca aactgaatgt ggctttttgt
     9361 ggcgatcagg caggtgctaa tctgtatcca ggcgaactat tcgaagatgt agatggaaag
     9421 ctggtttcct tacaaaagac cacgccagtt aatgacccac atgaactaag tatggctcat
     9481 tttgtgaatc gggcgctcgg tgaccagact cagatgattg cagatggctg gcaaggatat
     9541 gtcatccaga atctggtgga aaatttatat cgttcggcag aaacaggaga agttattacc
     9601 ttatgaaagt agaagaaaaa cagtttgatt tagagtatat caataagtat gcgagtcaga
     9661 tgaccattgg aaatggattt tttggtatca gaggaagcca ggaggaagac tatcggaatc
     9721 aagtaagggg aatgtttgca gctggtgtat ataaccgacc tttaggagca gaatcagccg
     9781 agttagtgaa tctcccagat gtcatcagat gggaaataaa aatcgacggt gaacattttt
     9841 ctcttgagac gatgaaagtt cttgcatacg agcgggcact agatttagaa atgggagagc
     9901 ttaaacgcta tgcgctcatt gaaactgctc aaggaaaaaa agtggaagtc attacttgtc
     9961 gtgttgctga tcaaaataat ctccatcagg cagccctgaa agtggtcatc aagccgttga
    10021 ccgaagactg ccaagtagat gtgaaaacgg gtatcgatgg acagcaaacc aattttggta
    10081 cacagcagtt ggttgaaaaa gaactgcgag tatttggtga cgatttgatc agtgcatcct
    10141 accagacaac agaaagtaaa attgatattg ggattgcagc taaattcaat aaagcaggtg
    10201 tattccaagc aaaaaatcgc cggatcaccg cttccttttc agaaaagatc agaaaaaata
    10261 cgtcctttac gctggagaag atcatcgtgc tctctacctc tcttcagcaa acagacccgt
    10321 ttaagaaaag tattgcccaa gcccagaaaa gcgttagtta tacagaaatt ttagagcagt
    10381 cgatgtctta ttggacagat ttttggcatc agcatcggat aacgatccaa ggcgattctt
    10441 ctttcgatca gttagcgatg gacttcgctg cttaccattt acagattatg actccccgca
    10501 atgatccaag tgttagtgta ggggcgaagg gactaactgg cgaaggttat aaagggcatg
    10561 ttttctggga tacggaaatt tttatcctgc ctttcttttt atatcagttt cctgaagtag
    10621 caaagaattt gctgctgtac cgttatgatc gattagaagg cgcacggcaa aaagcaagag
    10681 attatcacta tcaaggtgca cttttcccat gggaaagcgc acacactggt caggaagaga
    10741 cacccaaatt tgctgcattg aatatcaaaa ccggaacaag acaagaagtt gcttcagctg
    10801 ccgcagaaca tcatatcagt gcagaccttg cttatgccgt tcaagagtat gtccaagcaa
    10861 cagaggatca atcgttttta gaaacaaagg gaaaaacgct cattcatgaa acagcagctt
    10921 tttggctgag cagagctgta aaagtcgatg atcatttaga gatacacaga gtcattggtc
    10981 cagatgaata cacagaatat atcgacaata atgcatatac gaactatctg gcgcattata
    11041 atgtggcctt agctgttaaa tatcaagctg gcgatccgct ttttttgaaa gaatgtcaaa
    11101 attttttaga taagttatat ttgccagtgc ctaacaaaga acagctgatt ccgcaagatg
    11161 acacgtatct cagtaagcca gttattgatt tgaccactta caaagaacgt cctggcagcc
    11221 agtctatttt acttgattat gcccgtagcg aagtaaatga actccaagtc agcaagcaag
    11281 cagatcttgt catgctgtta tacttattac ctgagtattt ttctcaacca atcgtttcta
    11341 agaatttgca ttactatgaa aacaaaacaa tccacgactc atcgttgagt aaagcgattc
    11401 acgccataga ggcttgccgt atccaagaaa tggaatgggc gtatcattta ttccaagaag
    11461 cgtgcctgat tgatttagga ccagatccgc attcatcaga tgacggaatt catgctgctt
    11521 cattaggagc actatggcta gcagttatat ttggtttttc aggtattaca gtaacgaatg
    11581 gaactctttc tatttctcca agacttcctt cagcatggga aaaaatttct tttcctttta
    11641 tttggaaaaa tcacaggttg ctatttgttt tgacaaaaaa acaaatagta ataaaaaaag
    11701 agacgaaaga aacattacct atttttgtca atggagacca ataccagctg gaaaaagaac
    11761 tgatcttgga acggagggga aaataatgcg tattctgatt gcgccagatt ctttcaaaga
    11821 aagtctgaca gccttagagg cagcacaagc cattcaatca ggttttcaag aagtttttgt
    11881 tcaggctgaa tatgatctgc tacctatagg cgatggagga gaaggaacgg tttcatcatt
    11941 agcagacagt ttaaggttga agcggcaaac agcagtcgtt actaatgcat ttggcaaaaa
    12001 caaagaaatc cagtacgctt cagacggtca aactgcgatt tttgaaatgg cagaaatcgt
    12061 cggattgaaa gatgtcccac taaaccaaca acagccactt aggttatcca cgcgaggagt
    12121 aggagaactg atacgacaat tgttgcaaca aggtgttcga cacatcatca tcggcgttgg
    12181 cggaagtagt accaacgatg gcggcatcgg catggcagaa ggtctaggtt atgcttttta
    12241 cgatcaagat aatcaaaaag tagaagcact gggagaaaat ctaggtaaaa ttgctacagt
    12301 tgataaaacg aacgtgccta ttgagctgat taaagccaaa atcactgtca ttactgatgt
    12361 tactaatctt ttatgcggaa aagaaggcgc ttcttttgtt ttcggaccac aaaaaggctt
    12421 gaaagaaaat gaattagcag tggctgacca agccatgcat gatttttata tgagatttgc
    12481 ccctcaagta atcgaggcat cgggcagtag tgctggtggt ggaatgggtg caggactgtt
    12541 agcatttgct tcagggaaaa tagtctctgg catcgactac gtattggatt tactggagtt
    12601 cgataaacgg gtacagcaag cagacctcgt aatcgtaggc gaaggacgtc tagatggaca
    12661 aagtctaaaa ggaaaagcgc cagttgggat tgctagaaga gtaccagagg gcgttcctgt
    12721 gatagctatt tgcggaagtg ttggtaaagg aagcgaaaaa gcagcagatg ttggcatttc
    12781 ggccgttttt ccgatccttc ctgcagctgt gcctttacaa gaagctttac agcaagccac
    12841 tgataatctt catcgcacag ctaaaaacat cgcatcttta cttcaagtcg ttcattttca
    12901 aggaggtaat cgatgaaaat caaagcagca ctattcgatt tagatggcgt tcttgtagac
    12961 acagctcgtt atcattacga agcgtggctg gttttagcta accagctgtc cattccattc
    13021 actgagaaag aaaacgagca actgaaagga atatccagaa ccgagtcact agagcgattg
    13081 ctgtcatttg gaaaaatgga acagaaattc tcagaaaaag agaaatcagc ctttgctgag
    13141 caaaaaaaca atctatatct tcaagcgatt caaaaaatgg atgaaacatc cgttttgcct
    13201 ggtgcaatag ctgttcttga gtacttgaaa aaaacaaaca tcaagatcgg attgggatca
    13261 gcaagcaaaa atgcacgcct cattttagaa aaaacgaatt tgacaagtta ttttgatgtc
    13321 cttattgacg gcacgcaagt atcaaaagca aaacctgatc cagaagtttt tctcaaagga
    13381 gcacagcaat tgaatgtacc gccaaatgca tgcttggtca ttgaagattc agaagctggt
    13441 tgtcaagcag ctttggctgg taacatgcat gtattgggaa taggtgaaaa cataaatctt
    13501 ccttctgctg aatatgtgat tcctgattta accgtttttg atcaagtacg ttcgttttgg
    13561 catttatcag aagccgtatc acgtatataa tagtttccgt tttttctgtc acaagcaaaa
    13621 cgttatcctc cttttggaaa tcaaggtatg atgagaaaaa agggggattt tatatgacaa
    13681 aaaaagcagt tttcgcaggc ggatgctttt ggtgtatggt caaaccattt gaagagcagc
    13741 cagggatcat ttctgtgaca tccggttata ctggcgggca tgtaccaaat ccaacttatg
    13801 aacaagtaac aacaggcaca acagggcata cagaagcagt agagatcgaa tatgatccag
    13861 aagttatttc ttatgatcag ttggtggaaa tctattggca gcaaaccgat ccgactgacg
    13921 cattaggaca gttcgctgat cgcggtgatt cttatcgtcc agtgatctac tataatgatg
    13981 aagaagaacg aaatattgca gagcgttcaa aacaagcatt gcaagacagc gggcgattcg
    14041 ataagccaat cgtgacaaaa atcgaaccaa gaagcgaatt ttatcctgca gaagattacc
    14101 atcaggatta ttacaagaaa aacaagctcc attacaatct ttatcgagaa ggttctggac
    14161 gtgcaggttt ccttcgtcga cattggggcg tcaagaaata agaagccgaa aaagctactt
    14221 atggaacacc gtatatcaga ggttgtaaaa ccagcatttt gagctaatac tgagggtcag
    14281 ctgattgaac accatttagt ggagaggttg tgaacctgtc gcctagctcc aagtcacaag
    14341 gatttggtaa gagaacacta tatatcagag gttgtgacaa gtcgtttgtc acaacctttt
    14401 ttcaatacct aagatgaagg acaatcagca acgcactgct caaaaaagga atgaaaggca
    14461 gcttttccaa ctttttttta tgacagataa agtaaacaga aaaaacggat attccaaaca
    14521 gactagcaag aaacaagatc tgaagcaact cttctagaga caagccacca ctccaagaaa
    14581 gcatcaacag agtatcgcca gctccgagat aggattgacc atagcgaagg cacacaccgc
    14641 ctacgataaa cgttaacagc acactttgcc attggaagac gccggcctgc aaccaaaaaa
    14701 tccataaaat tgcccaagaa cagaatagcg tgtgagaatg gaccatgaag taaaataaat
    14761 ccatcaacga aaatagcaaa gccgaaagca tccatatgaa cgtcgaaaaa tttcttgcgg
    14821 aagaaaaagt aaagaaccag gcaaaaagac caccacataa ggcttctgcc aacaaatagt
    14881 agaagggcaa ccgacacctg caatagcggc agcgaaatcg ttggacgatg atcgagagaa
    14941 tcggaatcaa ttcataccaa gaaagcgaac gacagcattt gacacaatga gatctaggat
    15001 aaataataga gtgacctaac ggaatccgct gggcggttaa acataaaaat gatccgatac
    15061 agcaaccaat gataaaataa agtaacacgc catctccccc ttttcaaaac caagatacgc
    15121 aagcttaaac taaatttttg tacatacata aaatttgagg tgaaaaaatg aacgtttcaa
    15181 tcggattaga tatcggaacc acacaaacca aagcagttgc tttcacagat gaagcccaag
    15241 aagcagcatc cgcttatttt cgctaccctt tgatccaaga aacacaaggg atggcagaac
    15301 aagatcagga attgatcttt caaggtgtct gcaccgttat aaaagaagta attaaacagt
    15361 tgccttcaga cacaatcatt caatttgtct ccttctcctc tgcgatgcat ggcctgatat
    15421 tgttggatga agagaaaaca ccgttatctc gaatgatcac ttgggcagat aaccgagcag
    15481 cggacgaagc agaaaaactg aaatataccg tgcttggcaa agaattttat cggcagactg
    15541 ggacgccgat tcatccaatg acaccattga acaaaatcaa gtggctgcaa aacagccaac
    15601 ctgaattatt caaaaaaact gcttattttg tcggtatcaa agactatatc ttttatagat
    15661 tgtttggcga actgatcagc gactacggaa cagcttcagg aactggatat tttgatatcc
    15721 atgaattcca atgggcagaa gaagtgcttg actacttgaa cattcgaata gagcaattgc
    15781 cgcaagtctt tccttccacc tatcaagtaa caggtctacc atcaaaaaca gcagcagaac
    15841 taggtttgcc aaatgatata tcatttgttt tgggaggggc agacgggccg ctttctaatc
    15901 tagggttagg tgcttttggt gatacgatcg ccgctttgac cgtaggaacg agcggagcac
    15961 ttcgttttat tactactcag cctcagttcc atccagaaat ggagacgttt tgttatgttc
    16021 tggatcagaa acattgggta gtgggaggag cgactagcaa tggtgctggc atctttgatt
    16081 gggcagggca tacattttta caggaagtcg ttcaatctgc taaagaaaaa ggagaaaatc
    16141 catatgatgc actgctttcg gctatcgctt ttgtgccagc gggtgccaat ggtctgattt
    16201 ttcatcccta tttacttggt gagcgagcac cgctttggga cgcagatgcg tttggcagtt
    16261 ttatcggttt acagcggcaa catacagaaa aagaaatgat gaaggcgatt ctagaaggga
    16321 tctgtctcaa cctttatcgg attttaaaag gagtttgcca ggaaaatcag ctcacagaga
    16381 tccgtgctac aggcgggttt gctcaatctc cgatttttcg tcagatgatg gctgatgtac
    16441 tgggttaccc gcttgttttc cctactgtca cagaagcatc cgcattagga gctgtgattt
    16501 taggctggag aagcatcgga aagatccaaa gtatcagtga agcacaggaa ttgatagaat
    16561 tgaaagagca agttggagta caagaaactg atcataaaaa atatcagaaa atctatccat
    16621 tatttgtttc gacacaaaag catttagcac agacttatca gcaatttgct caactgcgag
    16681 aagaattagc tgattctgaa aaatgattgg ctttacggat aaaaaagcga actgaaaatc
    16741 gttctcaggt aaatgatttt gttgtacttt tcattgaaag tctactatta ttttaagtgt
    16801 aagaaaatgt taggaggcaa gaaagatgaa attccaacaa accaaagaag tattaaatca
    16861 attagttgca gatctaagcc aaatgtctgt tgttgttcac caaacacatt ggtacatgag
    16921 aggaccaggt ttccttacat tgcacccaat gatggatgag ttcatggatg atttgaacgc
    16981 tcagttagat gaagtatccg aacgcttgat cacattagac ggttcacctt attctacatt
    17041 gcgtgaattt gcagataaca caaaaatccc tgatgaaatt ggccgctggg atcgtactat
    17101 tccagaacgt ttggaaacac ttgttgcagg ctatcgttat ctagcagatc tttaccaaaa
    17161 aggaatcgaa gtttctggag aagaaggcga cgatccaaca caagatatct ttatcgaatt
    17221 caaaacagcc acagaaaaac gtatctggat gatccaagct catttgggca aagcgccaga
    17281 gatcgacgcg taaaaactgt tgttgaactt gaccgaaaaa gaggttgtga aatcagcgtt
    17341 ttgacctgag tattagagaa acaaacgtca aaatagttcc tcatattttg ccgttttttg
    17401 agctaatacc gagggtcagc tgattgaaca ccgtttacca agaggttgta agcctgccgt
    17461 tcagctccga gtcacaagaa acaattttaa aaaacagctt cttatgtttt atggatattg
    17521 tgacttgtga ccgaggagtt ggcaggagaa caccgtttat tcaaaataag gggttgtgac
    17581 aagacttttg tcacagcctc tttttgtttt tcattttgac aggaaacgac ccttttatat
    17641 aaaagaaaga aaagaagtaa agtttcatat aaatttttca atcaagcaga aaaacgttga
    17701 cattgactag attagcgggt aatatgttaa atggtattgt ttgccccaca aagagccccg
    17761 gaaactcgaa gtgtatgtca aacatcagaa cttaaattgg aggaaaataa cgtgcgtaca
    17821 acatatatgg ccaaaccagg cgaagtagaa cgtaaatggt atgtagtaga cgcaactgat
    17881 gttccattgg gacgtctttc aacagttgtt gcatctgtac tacgtggtaa aaataaacca
    17941 actttcacac ctcatttgga tactggcgat ttcgtcatcg tcatcaatgc agacaaagtg
    18001 aaattaacag gtaaaaaagc gactgacaaa atttattacc gtcacagcaa ctacccagga
    18061 ggattgaaat caatcactgc tggcgaattg cgtgctaaaa attctcgtcg tttgatcgaa
    18121 acttctgtaa aaggtatgct tcctaaaaac actttaggcc gcaaacaatt tacaaaattg
    18181 aacgtatacg gtggagcaga acatccacat gcagcacaac aaccagaagt tttagacatc
    18241 acaaacttaa tctaatagga gggaatttca ttggcacaag ttcaatatat cggcacaggc
    18301 cgtcgtaaaa acgcagttgc tcgcgtacgt ctagtaccag gaactggcaa aattactgta
    18361 aataaaaaag atgttgaaga atacattcca catgctgact tgcgtgaagt aatcaatcaa
    18421 cctttcgctg ttactgaaac aaaaggcgca tatgacgtat ttgttaacgt aaacggcgga
    18481 ggatacgctg gacaatcagg agctatccgt catggtatcg ctcgtgcatt gctagaagtt
    18541 gatcctgact tccgtttagc tcttaaacgt gctggcttac ttactcgtga cgcacgtatg
    18601 gtcgaacgta aaaaaccagg tcttaagaaa gcacgtaaag cttcacaatt ctcaaaacgt
    18661 taatatcctt tatatatcaa cgtttctggc acttttcaat tatttggaaa gtgcttcttt
    18721 tgtttttaag aacacattta agaacacata tcaatcacac ttattcaatc ctctctgaaa
    18781 agcttcaaaa acagccttat caactatatc tggtgtgttc acatatatct ttgttgtaga
    18841 aatatctgag tgtgttaaag catttgaaat ttgattcata tctgctccac cttgtctagc
    18901 tatagttgca taagtatgac ggagtttgtg tggagataaa tgaactaagt caggatgcct
    18961 tcttttaatt gaattgattc gatagtttag gtaatcggca tgaacaggac aatttacttc
    19021 tccagatggt ttagtataag taaagagata ctgatctaac gtttgcttaa tttttaattt
    19081 caacaattga tcagcttgta ccgatttcca ttcacttagc aatgtcatta caacttctgg
    19141 tacttgaatg acggtatctt ttcgaccttt tgtaaacttt tttctttgat atttatctaa
    19201 agtatgttta agacggaccg tttgtttttc aaaatcaata tatttccatt gcaaagcgta
    19261 agtctcactt tttctatcac caagatacag ggtaatcata aaaagtgtgt aatcatgaaa
    19321 agtaagtaaa tgattattaa aatcatcatt tactgcttct atccaattag taagttcttt
    19381 tgatgatagt gcttgcttac cttcttgtat tcttttttct tctaaagcat tttttttagg
    19441 tgcagtgata ctttgaataa ttttagtagt tcgattaaat tcgatataat ttagtatttc
    19501 tgcaatatcg aacatggaac gaacatatcc ttttatgatt tttatatttg catattcttt
    19561 cgattttttg gttaattcat ctgatattat ctcagtattg atatttagat aattcattgc
    19621 gtattcacca aacataggta aaatatgcaa ccgaaatata tcttttgtat tactaatggt
    19681 tatatcacta ggaggcctgt ttgatctaat tgtttgacct aattcatatc taggaagcca
    19741 tttagattcg taaaattttt taaacgttat ttttcctttt aattctaatg agtttgcatt
    19801 ctcctctctc aaaacttttt ctattttctt cttcatatca ttttcggctt taatcgccaa
    19861 ttgcctattt ggaaatgttt tttgatactt ttctgatgca attcctgtta tttctttaaa
    19921 cctttttgga tatctcagat tagttttata tttcccattt gaaagctttg taggcaaaat
    19981 cctcactcct taaaaaaagt aaggcagtat atttcactaa ttttagtata tgcggcgaga
    20041 agaaaatttc aagttatttt aaatgtattc ataaagtctt taatatcttc tacgtcaaag
    20101 cgaactacac caccaactct tattactggg aaattatata tacgaatcca cttatctaga
    20161 gtattattat cgattcctag aaatgcacag gtttgttttt tattcaggta gactctggat
    20221 tctataaaat catctcctaa aatagtagtt atgaaatttt tgaattgctt tgggtaagca
    20281 cataggaatt tcacctctcc ccagtttacg gcgagcctta cggaagtatc attatttgct
    20341 gctattgtca tggcattttg ttttcccaga acaaaaagaa atctctaagt atttgtcgct
    20401 aatcaggtca tggcgtactt gagtttctag ctcgaatagc agggatcgtt attcaaaaat
    20461 tgtatttaat tgtcaatgat caaaaatagt ttttttccta ttcactatta ataacgataa
    20521 acatgtataa aaagacacac tacgaaaaaa gttaaatgga gtttactgat tttcatattt
    20581 gtatatggaa cagacatagt cttgaataat ttttataaat gttttgatgc ttatcaactt
    20641 attcaacccg ctatccactt caagtataat ttttccatac gccaataaag tagttttagg
    20701 agcatgttct catttgagaa cgctcctttt ttatatattt tgaaagctac ttactatacg
    20761 cgtagtttca aatagttttg tcattctaat cttcagcaac agaaaaaaat ctaaactata
    20821 aaatttaggg ttgactaaaa tataattttt gtataccata tgatcgtgat aatcattatc
    20881 atttagaagg agaaagttat gttagaagtg aaaaagctta atgtttgtta taacgatttt
    20941 ttagcattga acgagatttc tttaaaaata caagaaggtg ctttaacagg tattattggt
    21001 ccaaatggtg ctggaaaatc cacattgctt aaagcaatgt taaatattat ccctcatcag
    21061 ggagaggtct ccattaataa tgaagatatc aataaaaaac tggtgaagat tgcatatgta
    21121 gagcaaaaag ctgatattga ttttactttt ccaataaaag taaaagaatg tgtatctatg
    21181 ggaac
//
LOCUS       DAXLPQ010000046        20600 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.046, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000046 DAXLPQ010000000
VERSION     DAXLPQ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.046"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            107..301
                     /locus_tag="ACF3UO_002010"
     CDS             107..301
                     /locus_tag="ACF3UO_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657997.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            570..869
                     /locus_tag="ACF3UO_002011"
     CDS             570..869
                     /locus_tag="ACF3UO_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3657998.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(966..1400)
                     /locus_tag="ACF3UO_002012"
     CDS             complement(966..1400)
                     /locus_tag="ACF3UO_002012"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3657999.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1632..2342)
                     /locus_tag="ACF3UO_002013"
     CDS             complement(1632..2342)
                     /locus_tag="ACF3UO_002013"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFD3658000.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2332..3192)
                     /locus_tag="ACF3UO_002014"
     CDS             complement(2332..3192)
                     /locus_tag="ACF3UO_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFD3658001.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3197..3835)
                     /locus_tag="ACF3UO_002015"
     CDS             complement(3197..3835)
                     /locus_tag="ACF3UO_002015"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFD3658002.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3850..4149)
                     /locus_tag="ACF3UO_002016"
     CDS             complement(3850..4149)
                     /locus_tag="ACF3UO_002016"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3658003.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(4192..5676)
                     /locus_tag="ACF3UO_002017"
     CDS             complement(4192..5676)
                     /locus_tag="ACF3UO_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3658004.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(5696..6157)
                     /locus_tag="ACF3UO_002018"
     CDS             complement(5696..6157)
                     /locus_tag="ACF3UO_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3658005.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6175..7242)
                     /gene="ulaG"
                     /locus_tag="ACF3UO_002019"
     CDS             complement(6175..7242)
                     /gene="ulaG"
                     /locus_tag="ACF3UO_002019"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFD3658006.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7460..8230
                     /locus_tag="ACF3UO_002020"
     CDS             7460..8230
                     /locus_tag="ACF3UO_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3658007.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8503..9330)
                     /locus_tag="ACF3UO_002021"
     CDS             complement(8503..9330)
                     /locus_tag="ACF3UO_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658008.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9897..11132
                     /locus_tag="ACF3UO_002022"
     CDS             9897..11132
                     /locus_tag="ACF3UO_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3658009.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12131..12391)
                     /locus_tag="ACF3UO_002023"
     CDS             complement(12131..12391)
                     /locus_tag="ACF3UO_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFD3658010.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12418..13719)
                     /locus_tag="ACF3UO_002024"
     CDS             complement(12418..13719)
                     /locus_tag="ACF3UO_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3658011.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14011..14469)
                     /locus_tag="ACF3UO_002025"
     CDS             complement(14011..14469)
                     /locus_tag="ACF3UO_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFD3658012.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14482..15312)
                     /locus_tag="ACF3UO_002026"
     CDS             complement(14482..15312)
                     /locus_tag="ACF3UO_002026"
                     /inference="COORDINATES: protein motif:HMM:NF023401.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFD3658013.1"
                     /translation="MINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYD
                     KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYY
                     LYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDI
                     AISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVETITLRKPISDFHKGL
                     MEAQVAAEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK
                     "
     gene            complement(15325..15812)
                     /locus_tag="ACF3UO_002027"
                     /pseudo
     CDS             complement(15325..15812)
                     /locus_tag="ACF3UO_002027"
                     /inference="COORDINATES: protein motif:HMM:NF014148.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            complement(15823..17265)
                     /locus_tag="ACF3UO_002028"
     CDS             complement(15823..17265)
                     /locus_tag="ACF3UO_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3658014.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17252..18016)
                     /locus_tag="ACF3UO_002029"
     CDS             complement(17252..18016)
                     /locus_tag="ACF3UO_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFD3658015.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18120..18995)
                     /locus_tag="ACF3UO_002030"
     CDS             complement(18120..18995)
                     /locus_tag="ACF3UO_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFD3658016.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19250..19334)
                     /locus_tag="ACF3UO_002031"
     tRNA            complement(19250..19334)
                     /locus_tag="ACF3UO_002031"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19298..19300),aa:Leu,seq:caa)
     gene            complement(19352..19423)
                     /locus_tag="ACF3UO_002032"
     tRNA            complement(19352..19423)
                     /locus_tag="ACF3UO_002032"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19389..19391),aa:Gln,seq:ttg)
     gene            complement(19433..19505)
                     /locus_tag="ACF3UO_002033"
     tRNA            complement(19433..19505)
                     /locus_tag="ACF3UO_002033"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19470..19472),aa:His,seq:gtg)
     gene            complement(19567..19651)
                     /locus_tag="ACF3UO_002034"
     tRNA            complement(19567..19651)
                     /locus_tag="ACF3UO_002034"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19615..19617),aa:Leu,seq:caa)
     gene            complement(19672..19742)
                     /locus_tag="ACF3UO_002035"
     tRNA            complement(19672..19742)
                     /locus_tag="ACF3UO_002035"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19708..19710),aa:Cys,seq:gca)
     gene            complement(19788..19859)
                     /locus_tag="ACF3UO_002036"
     tRNA            complement(19788..19859)
                     /locus_tag="ACF3UO_002036"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19825..19827),aa:Gln,seq:ttg)
     gene            complement(19871..19943)
                     /locus_tag="ACF3UO_002037"
     tRNA            complement(19871..19943)
                     /locus_tag="ACF3UO_002037"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19908..19910),aa:His,seq:gtg)
     gene            complement(19946..20019)
                     /locus_tag="ACF3UO_002038"
     tRNA            complement(19946..20019)
                     /locus_tag="ACF3UO_002038"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19985..19987),aa:Trp,seq:cca)
     gene            complement(20026..20106)
                     /locus_tag="ACF3UO_002039"
     tRNA            complement(20026..20106)
                     /locus_tag="ACF3UO_002039"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20070..20072),aa:Tyr,seq:gta)
     gene            complement(20108..20183)
                     /locus_tag="ACF3UO_002040"
     tRNA            complement(20108..20183)
                     /locus_tag="ACF3UO_002040"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20148..20150),aa:Phe,seq:gaa)
     gene            complement(20219..20291)
                     /locus_tag="ACF3UO_002041"
     tRNA            complement(20219..20291)
                     /locus_tag="ACF3UO_002041"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20256..20258),aa:Asp,seq:gtc)
     gene            complement(20301..20373)
                     /locus_tag="ACF3UO_002042"
     tRNA            complement(20301..20373)
                     /locus_tag="ACF3UO_002042"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20338..20340),aa:Val,seq:tac)
     gene            complement(20389..20460)
                     /locus_tag="ACF3UO_002043"
     tRNA            complement(20389..20460)
                     /locus_tag="ACF3UO_002043"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20425..20427),aa:Glu,seq:ttc)
     gene            complement(20475..20563)
                     /locus_tag="ACF3UO_002044"
     tRNA            complement(20475..20563)
                     /locus_tag="ACF3UO_002044"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20527..20529),aa:Ser,seq:gga)
BASE COUNT         6499 a         4313 c         3273 g         6515 t
ORIGIN      
        1 tttcaaattg attcttttta tttatcataa agatatagat acataatcat tttcacttac
       61 atatatttga atattaacta aaaacagcaa gaaagaagag gatcaaatgt attatgtaga
      121 agtaaaaaca aaaggcgtca aaaacaaaca atatgtgaaa ggtatcagta acgaatatcc
      181 tttacttggt tcatggaaag aagctgctcc tttttccaaa ccatgtgcca taaaaataaa
      241 gaacgagcta gaaaaagaac tgacttgtgg caaagctgtt gtagatatca tcgaaaagta
      301 aatccaatgt atagaaagga agatcacaca tgaaaagcga cgtacaaatt gctaagatta
      361 tagaattaga agaagaagac gcagtgttga caattgaaaa aaaataaatg tttgtatacc
      421 atatgattat ttcaatatgt atcctggaat tggagatctc gtagagctat atcaagatga
      481 atcaaatata cttgtcattc atcatgaaat atagagactt ataaaattgt ttatttttat
      541 aatgtatcag tatagaaagg aaataaaaca tggattatac tgttgaattt gacagtgaac
      601 tacttaagca atttccacaa gaagaacatt tcatgtataa agaagcaatt tcccacaaag
      661 tgacagagta tttggagcat aatttttttc gtataaagcc agtgcgtact cgttcggcaa
      721 aaggaatata cgagatgaaa gtcaaaatta ataaaaaaaa ttatcgcata gcatttgctt
      781 taaaaaaaaa tcatgtgttc attttttata ttagttcgaa tttgcaaaaa attgtatttg
      841 ataaagaggt gagtaaaaaa ataaaatagc tgagcattgg aggatagatt gagtgatact
      901 aagtctatcc tcttgttttt ctaaagaact aagctagaat tttttctttt gtacgttatt
      961 atatgttatt tgtcattacc aaaaagcacc ttttttcttc tagtatctat gacataagaa
     1021 ataccaccca tttcctttac ttgaacaaat cctactgatt cataaaattt ttttgttttc
     1081 tcagtatcat ctgtcaataa ttcgatttgg actggtccat aactagtgat cttctccaaa
     1141 gcttcattca aaagcacttt gcctattcct tggcgctgat acctcggatg aatgaggata
     1201 tcttgaataa atgcgatcgt cgcaaaatca gtgatccaac gaacgattcc gataatcttc
     1261 ccttccccat tacgctttat cagagattca gattgttcaa atgctctagc taaccttgca
     1321 gtgtcttttg tgtaattcgt ccaaccaacg ctcttatata attcagaaat ctcatcgatc
     1381 ataagggaat caatattcat ttttttcttc ctttcttata caattctccc tctaataata
     1441 cagttctttg actatttaat ctatcacata taactctcct gtaaagattc tctcgattcc
     1501 ttaaaatctc tctttccttt tagaatgcat cctttttgat aaataaaaag gttgtgataa
     1561 attttcttca caacctctgt ttctctctat caagtgttat cttttaattt tctaccctta
     1621 ccctagcatc tctattgccc gtagtatgca tactttccat gtttgcgaaa ataatgttta
     1681 tctagtaaat attgcgggat ttcacatata ttggggttga tcagctcgtt ttctttggcc
     1741 atcagacaaa tttcatctaa gatcaaactg ttttctactg ctttcatagg tgaatccccc
     1801 catgtgaacg gtccatgtcc atagacaagt actccaggga cttcgtttgg atctaatttt
     1861 ctttccttaa acgtctcgac aatcacattc cctgtatgaa cttcgtaagc ttctcttact
     1921 tcttctttcg ttaattggcg tgtacaagga accttaccat aaaaagcatc agcatgagtc
     1981 gtgccataag ctggcaaatc gcgtcctgct tgcgcccaca tgacggagtg cgtggaatga
     2041 gtatgagtaa tagcagttat atcttcaaaa gtttgataca aaacaacatg tgtggggaga
     2101 tctgaagatg gttttaagct atcttcttct attatatttc ccgacaaatc tgttaccacc
     2161 atttgatctg cttgcatgca ttcatatctg acaccgcttg gcttaatgac gatgactcct
     2221 agctcacggt ccacttcact cacattgccc caagtcaatt tgactaatcc gtatcgcggc
     2281 aatgccagat ttgcttcaag gacacgttgc ttcattgctg caattttttc ttcacaagac
     2341 atcatagcca gcctccttca atttagaact taagtagtct tttgcctgct ggatttctct
     2401 tcgaaagtct tggctttttt cactccacat ttcaatcaga aatgttccat cataatctag
     2461 acgtttcaaa tgtcttaata atccaagaaa atcaacacaa ccgctaccaa aaggaacatc
     2521 acgaaactgg cctgaatatt cttttgttac agggtaagta tcttttaagt ggatagcagt
     2581 gatataatcg atccctttct caagttctcg agccggatta ttttccggcc atgcggacaa
     2641 attgcctagg tctggatata cttgtagaaa aggggaatga atctgttctt tgatttctaa
     2701 aaattttgaa atggagttca taaatggatc atccatgatt tccacggaaa gaatgatgcc
     2761 atatttagaa gcttccttta cgctttcttt tattccttcg ataaagtctt ctctggaatt
     2821 cattgatttc tcttcataat aaacatcgta tccagctatt tggattactt tgacgcttag
     2881 attatgcgcc aaatggattg cttttttcat tagttgtttc gctgcttttt tcttttctgg
     2941 atcagcagaa ccaaacggaa atcgccgatg cgcacttaaa caaatcgaat ggatacgtac
     3001 accggagctg aacatctctt ctctcagctc agctatcttt tcttcagacc aatctaatcg
     3061 tgctaaccgc tcatccgtct catcaatcga catctcgata aaatcgaagt ccatttcttt
     3121 tacaagggaa aaacgttctt tccatgaaat atctttgggt aatgcttttt cataaatccc
     3181 aatttgagcc atttccttac ccccagatac gaatgatctc atctttgaag ttttgtgcgg
     3241 ccttcatcgg atcatttgct gctgtaatac cacgaccagt gataaaggta tacacatcga
     3301 tcccttcaaa taagtgtaat gtgtgtggat ttaatccacc agttacagaa acattaaagc
     3361 ctagttcaat cagttttttg atcttcgata aatctttttc accccaagtt tcaccagata
     3421 acagcgcatc acggctttga tggtagatta cctgccggat accgatgtta tgccaatcca
     3481 tggcttgttc aaaagtccaa ttgccgtaga gttctacttg caattcacct atttcttttt
     3541 gtgctgcctc catagttgga atcgttgcac aacaaatgac tgtcatccag tctgctcctg
     3601 cttttgcaac attactcgcc actgttcctc cagcgtctgc acatttcgta tcagcgacta
     3661 gttttttatc tgggaacata ctgcgaatac agcgaatcgc tttttgtcct tcctgtaagc
     3721 aaagaattgt gcccacttca ataatatcta ctacatcacc aactttcata acatctccta
     3781 atgcatgttc taagtcattg tgatctaacg caatttgcaa attcggcctg ctcatcttag
     3841 ttccttcctt tacttgtttt tttggtacca ctttgtttca gcaaattttt cactgatttc
     3901 tttggctgac atcacatttt tgataccgat aactgtaact tcttttttct ctgcctgagt
     3961 aaacatattc aaaaaattga ctggcgtaaa aactacatcg tattggccag ctgaactttt
     4021 tccctctgaa atggcacaat gatggatttt ggtaattggt acgtttagtt ctttcattgc
     4081 tttttccaca cttctcatca tcatcaagct tgttcctgat ccatttgcac acgatactaa
     4141 aattctcatc ttaatccctc cattatgagt gttgtctaat cagattttct tttatactct
     4201 ctgcttttct gcatatgtgt catagtcttc tacaatcaaa aaataaccct caggattttt
     4261 ccgatattgt aactgcggaa tagccaataa accaatgaca actacggcaa ttccagcata
     4321 acctaggact ttcatgatta ctgtaaacaa tggccaagct gttgcccagt cgaacatccc
     4381 gatataacca ccatatgttg acatcccaat ccatgtagcg aataatgctg aaccgcctac
     4441 ttgtatgatt cctgaaagaa acgggaacag gcaagcggct ttgaatccac ctcggttatt
     4501 ggcataaact gctataacgg cattatcaaa gaacaacgga atgaaaccgg ctatgacgat
     4561 cgttggtgat ttcaataaaa tcagtaaacc aatcatcaaa aactgtccca aagcaccaaa
     4621 caagaaccca atcgttaccg catttggcga accaaagcca aaagtagcag ctacgtcaat
     4681 tcctggaaca gctcctggta aaattgtgtt tgagattcct tggaaagatt gagttagttc
     4741 atcgacgaat gtccgaacac ctaattgcaa gatcgccaga tataccgcaa aatttaaaga
     4801 agtcgtcata atgtagaata agaaactctg tccttcttgc atgaattgcg cttgaatcaa
     4861 ataatctttg cctagtacaa tcagaatgat cccaaagaaa aatagcatga gtaacgaagt
     4921 agcaaccata ttctcattga aaatcgacaa gaatcctggt aatttgatat cttcgatttt
     4981 tttgtcttgc ttgattgatc tatttttctt ttcatcccgc tttttcatcc actcagctaa
     5041 ttttgcaaat ataaagattc cgaacatttg ctgatgtgcc actgcaaatc cggcaccttc
     5101 tgtcaattcc tgcgtgattc ctactgttaa gttagaagct actgcccaat aacaacctaa
     5161 aatcagtccc ataaaaatca atacttgtat cctacctaga tcaggaaagc aaaacagtaa
     5221 aatccaaaaa gcggtagctg cttgttgaac ctgaacgttt ccggtagtga aaacggaacg
     5281 cagtttcgta tatttctgaa aacggactaa taagatattt aaaacaaatg caatcagtaa
     5341 taaaatcatc acatctccaa aggtacggcc aaatgtctcc attaatccag catccacagc
     5401 attttgtcca aaataaggat ctgtaaccat ggcatccaaa ttgaaccgtt cctttagtcc
     5461 aaccaaaatc ggccgaaaat tattgaccaa accaccagag ccaacagtca aaataaagta
     5521 accgaccgtt gcctttaaga atccagcgat gcattcatga agcgggcgtt tcagcaaaat
     5581 atagcctaat aacacgataa aaccaatcag gtatgctggc tgcgtcaaga tatttgttgc
     5641 aaaatacgtc caaatgctta acaaaaattc ccccatcttt tttctcctct atcaattaat
     5701 tatattctgc catcacaact tggtaatcat cgatggagtt cgtagagatg agacgctcaa
     5761 ccaatccatc tgtcattaat aattcggata atttttggat attttctaga tgttcttctg
     5821 gatcttttgc tgcaagtgta aaaaacaaac tagccgtttt ctcctcatcc tccccttcac
     5881 tttcaaaacg gattggctgt ttcaacttgg taaatgaaat agctgttcca aaaacaccat
     5941 cacttttttc tgaagaatgc ggcattgcta cttgaggtgc gatcacaata taaggaccgt
     6001 atttttctac acaatggatg atctcctcca catacgtttc atcaataatt tccttatcga
     6061 tcaatacaag acagctttcg gcgatagctt cacgccaatc cgtgatttct ttatctgggt
     6121 aatgaatcaa ttgatggtca aaaaagtatt tcagcaagaa actccccttc tttcttataa
     6181 aaacgacgga aacggtgtat cattttcaat cgagaagaca tcttcaaatc ctcgataaaa
     6241 attaaactca agatcatctt tgtttgtcgg atagatgaat ttcccgccta cttgccagat
     6301 ataaggttta aatccatact tcaggcgatc ctttttgaat ttccaaattt cagtgatctc
     6361 ttttgaatca gccataaaat tagaccaaat atcgtagtgg acaggaatca ctacttttgc
     6421 attcaatgac tccgccatgc gcagcatatc aacagaagta actttgtctg ttatccctcg
     6481 tgggttttca ccataggccc ctaaacagac atcgattttg tgttcattac catgtttggc
     6541 aaataaattg gagtaatgtg aatctcctgc atgataaaga ttccctcctg atgtttcgaa
     6601 taaatagttt actgcaattt gatccatctc ctgaggcatt tttcctttta atacctcttc
     6661 tggatcttca caagtgacca acgctgtccg atcaaacgct tctaaagcta ctacattgat
     6721 gtctttgatt ttgactgcat cacctggctt tactgtaatc gttttttctt caggaattcc
     6781 ccatttttgc cacgtgcgaa ccacttcttt tggcccaatg aatgttgctt caggacaatt
     6841 ttgatgaact gctgcggctg tatggatatc tagatgatcg gaatggatat gtgtaacgat
     6901 taaagcgtct acatttttta tcgcaaaagg atcgattacg aaaggctgag tacgtaaatt
     6961 aggctgcata ttttgaacgc cactcatacg catcatctga tggccttttt tcatcatgcc
     7021 attcccatga ctacgttttc ccgtcccaca ccatagatca cataaaatat tcgttccttc
     7081 atgacttttc agccaaattc ccgtacagcc cagccaccac atagcaaaag ttccaggatc
     7141 cactacttct gtttcgattt cttcattcaa gtatgtgccc cactcaggaa atgtttctac
     7201 taaccacttt tcttttgtta cttcattgac agttttactc atttgcttgc tccccccata
     7261 tcgttgttcc aacttacaag taaatattaa tgtgtatcag catccatgga aaccctttta
     7321 tatgaccgtt tgttttttat atgattttct ttcagtaatc aatgattgtt tcagtataat
     7381 aaagacagat atgaatgttt aaatgaacaa ctagtcaaat aaatccatgg atcaagatgt
     7441 ccctcaggag gcaaaagtca tgaaaaactc acttgtcaat attgaaaaac gtcaaaaaga
     7501 aattttggaa ctgcttcagc agactgaaca actatcaact ttcgaattag ctgaatccct
     7561 tgatgtatct attagtacga tacgaagaga tttaaattta ttagaagaaa aaaacgagat
     7621 catacgcaat tacggttatt gttcttataa ttacaaaaac cagactgatt ttgatcaatc
     7681 tggtcctgaa aggattaaac aagcgattgc cagagaagct agtaaataca ttaacgatta
     7741 tgatacgctg tttatcaatt ctagctcgac tgcgttgaaa acactggatt ttcttcaatc
     7801 taaccatttg acagtcatta caaacaacgt gaaaatcaat tactctccgc acaaagataa
     7861 ttgtagttat attttaactg gtggagagat gcgctttcca aaagaagcac tagtgggcga
     7921 catcgcatta aatacgattt cttcagtcaa tgcagacatt tgtatcattg gctgtagcgg
     7981 agtcgatgta gtacatgggg tcacaacaaa gatattaaat gaatcaacga tcaacgaaat
     8041 gatggtcaac aagacaatca aatgtaagat tttagtcgct gatcatcgaa aaatcggact
     8101 gacatcaaag ttcaagattg ctgatatttc agtctttgat tatttgatca ctgataaatt
     8161 ttgttctgaa aaagtattag aggagatcag aaatacgggg ataaaaacca ttcaagtaga
     8221 ttcattttaa gaaccaggac gtaaatatgt aaataggatt atcaaaaaaa tgaataacaa
     8281 atttatcgat aaatgaaaaa cacgctacgc tcaaattgat aaaggaatcc caagatgtgt
     8341 ccatccaatc gataccatca taatctattg cttcttttat aaccgttata tgttgcctaa
     8401 ataggaatca aacaatatcg aaaaaaggag gtatgacaaa agtcacacct ccttttttcg
     8461 aataaacggt attcaaatca gaacactgat ttcacaacca ctttatttca ggtcgttttc
     8521 aatcaccttt accgcgtaat catttccgtt gaaacgcgct attttttttg cgtccatata
     8581 tctttctaaa taatcatctt ctcctaattg cttatggcaa gaagcaattt cataaagcaa
     8641 gtattccaat gcataagtcg atttatgttt cttattatac tcaataccct tctcacataa
     8701 ttggattgct ttatcataat cctcgatttt acggtaatag gtggcgatat cataatatac
     8761 aatgcagacc atcagattat caaaatcagt ctcactcaat attttaagtg tacgctccac
     8821 ataaactttc gcaaaatcta attctccttt tgacaagtag atcattgcca cgtttgcagc
     8881 tgcttgtaag tgatggatat ctgtttcggt cgtttgttcc aacacttgat taaaataaaa
     8941 taatgctgca tctggttttt tcgcataaag atgatcaagc agtccttgat aaaataaaat
     9001 ttgatttaaa agatcagaat tacttacttt ttcctgatcg atcgtttgta aaattttata
     9061 agattcttgg tattttgata cagaattcaa tgattgaatc tcatttattt ttttcctgat
     9121 tttgtcttct tctgtttcta ctaatatatc ggagatctcg acattcagct ttttgcaaag
     9181 cgcacttaag atattgatgc ctggcgacat attcttgttt tcgatattgc tgacagttgc
     9241 ttgttcacaa atgccttctg ctaattgtac ttgtgttaac ccctttttct ttcggtattc
     9301 ttttagtaat gctccatcta ctttaatcaa aacaatttcc ttccctttaa aaaattattt
     9361 ctcctttata tcatacacaa aaaaaagttc taaacaacca aaaatgttta gaacagaata
     9421 aaaattttaa ttttaaaata atattcaaat taaacaactg gcgtatctgc tccttgattt
     9481 ctttttgtgt tatctgaata attatcgttt acagttataa cacatagtga aaattgtcat
     9541 ggcgagaaag tctaagaata tttttaaaca taactatttc tttcttacgt gtgtataatg
     9601 acgacagcac acctatcaat taatataatt attttatttt ttatgttctc atgtttattt
     9661 ttaatgacac aacttctcgt atttatctgg cacaacatat aaatcgatca aaaaattgtt
     9721 gcgtgttttt ttgaaaattg gagtttcaac ttgattacaa aatttaaatt tagaagttgt
     9781 gaaaacagcg agagacagtt taatattcaa aatatacata ggctactcga acgctgtgtt
     9841 ttttagtata ctagtaagaa acgaagggat agactcattc caataaggag gatttcatga
     9901 agacaattct ttttgctcct gcagtattca atttagctga gacaacacga atgattgagg
     9961 ttgccaaagc tatgaaagac cgttattact gtgtattctt tggcttttct aaaacttttg
    10021 ctcctttgat cacagaaagt ggctttgagt atcatttact agcgccgatc cttacgaaaa
    10081 aacaagaaga acaaatcata aaatttgacc agttgcgtac acttaaaaac ccttttacca
    10141 aagaaatggt tgcctctcgt atcactagtg aacagagtct gattgctaag tttgagcctc
    10201 gactgattgt gacaggttcg aatgtgacaa tttttttatc ggcccgcaat aaaaagattc
    10261 ctttagtata tgttaaaccc tatgctttga gtgaaccttt ttttcaatca gagcatgcgc
    10321 tgatgcccca cgagttacgt ttcttcggcc ctttaagcaa tcccctttgg cactggacaa
    10381 aaaagcgtat agtaaatacc cgatggatcc ccaatgcctt caaacacgct gcacaaaaag
    10441 aaatgcttcc tttaccaaaa acaagtttac aaatgatgga tgctgatcta aatctcatca
    10501 caacgcctaa actatttttg gaagaagaac agctgccgga aaattatcga atcgttggtc
    10561 caatttttgc taagctcagt acttccttgc ctgaagaagt gctaactttt atacagcgaa
    10621 agcaacaaga aagaaaacgt attatctatt tcgcaatggg tagttcaggc aatccgcgta
    10681 tgttacgcaa aattttgttc ttcttacaaa aacaaccgga tctagcggtt attgcaccta
    10741 ttgactatct gcttgatgac attcaatctg actcagaaga tcttttaata acagaatatc
    10801 tgtctagtca tcttttgcat gaattcattg atttttcttt tatccacggc ggggaaggga
    10861 ccgtccaaac tgcctgtgaa tccggcaaac cgtttatcgg tgtggggatg caatttgagc
    10921 aaagctgtaa tattgactat tgtgtaaaat acggaaacgc aatcgccctc acaaaaccag
    10981 tgactgaaag aaaactgcag attgctctgc gcgaagtttc ttcacccaag attcgtcagc
    11041 aggcacgcac gctgcaagcc gtttttccaa taaatggtcc acaacaagca attcaagaaa
    11101 tcgaaacctt cctgagcaac cacccaatat agtttcaagt agaaaaagct tttttaatag
    11161 agactcatca gtaatttcgc tattcgagac ccagacagtg aaaatacaaa aaaagtaaat
    11221 agtggattga aaagttagag ttacttaaat tacggtgtct aaaaaacaca aaatcatcct
    11281 taaaataaaa gatctgacgc aatccaaatg agcataggta gcgtctgcca tttattctta
    11341 gtcaaattct ttgacacctt tctctggttg gatcatctca acgtttcttc aaaagaaaga
    11401 ccataataat taggcaaata cattttctta aaatgtgtca tatagatcta gaagcatcgc
    11461 tttgtagaga tttgtgctgc tagtcccttc aacaattact aaatcaaatg taggatttac
    11521 cactttatct ttgataatca acctccctct tctgttgaga caatgatctc gcaatccgat
    11581 gcatactcct atataaactg ccagcaatcc ccacatgctg agtagatcat gtcagaatgt
    11641 tctatgtcgt cagcaacgat aaactaaaag tcacgttcac catgactgat tgctattccc
    11701 agcgcaatta tttctataca cgtttcatga tttgaataaa cactctcatc atacatatta
    11761 ccattcatac accatactgc agcccctact atatggttgt aagctcccaa atctatattt
    11821 gccttgatca ctttggtagt agatcgacta attcttaatc cattgctgat aaaattttca
    11881 tttttgcctc cttctttctg ccaaaacagt taaaacaata ataatcttta tgtaaaaaag
    11941 ggctgtgaca aaagccttgt cacagtccca tattccgaat aaacggtggt caaaagcttg
    12001 catctgcggt aataagttca accaaacgaa aaataagcca acatttcaca aaaatttaag
    12061 aagcaatttt cgtaaatttc ttcttatttc ttgaagctaa ccacttctgt cacaaccact
    12121 tttagaacat ttaaagcttc gatgtgacaa accatctatg ctgctcgatc ataaaattga
    12181 tagcaaaaat tccacaaagt acatatgtcc cccatgaaaa caaaacattc atatgcggta
    12241 caatgatctt tggaagaatc acgatcaaaa atgatgccag tgcccaaatc catcgattga
    12301 tttgaatatg atatgtagct agcatattca atataaggtg actagccgtt aataaaaaga
    12361 taaaaacaaa aaataaaatc agccaataca ttgtttccca ccttctaaaa accaaactta
    12421 gacagtttgg acttcgtttt ctccacgact ttgttcatct gacagcatct ttttatcata
    12481 agcttttaca aatggataat agataataaa tgctatcaat gtgttgatca tgatcaagat
    12541 aacaacacgc cagtcatttc ctgctgaaag ataaccgccg attggagctg gtaatgtcca
    12601 agttggcaaa acagtaaatc tattgaccat ttctaatttg actgcaaaat aactgataat
    12661 agtcaaaact aaaggaacta agttgaacgg gatgaacatg taaggattca acatcatagg
    12721 agctccaaaa atcatgggct cattgatatt gaagatacca ggaataatag aaaaacgacc
    12781 aacctctttc aagaattttg atttacagaa gaatataaac aaaacagata ccacgatcgt
    12841 tgctcctgca ccaccaattg ttaccgtcca ttgataaaac tgttcaggag cgatataggg
    12901 taattgggtg gcagctgtac catctgccaa tgcctttgca ttctcatcca acatgatcag
    12961 ccacattgga cgaacaacag cccctacaat actcatgcca tggataccaa atgaccacaa
    13021 caaatggatc aaaaacattg gtagtaaaac accaagcaaa ttattcccta aaatattggt
    13081 taaaggctcg aataacgata ataaggtagc gtttacatca aagcccgcga cgcttcgaat
    13141 cagccaagta attgttaaaa tgactgcacc tggaatcaat gcctcaaaac tacgggcaac
    13201 agcaggtggc acttgttctg gcattttgat agtaatattt cgatttttaa agaaacgata
    13261 tacttccact gcaaaaatca tagataagat ccccgcaaac atcccagatg ctcccaaaga
    13321 actcataggt aagacccagc caagaggtgc cttttcagga gttaaaacgt ttacaggaac
    13381 ttgtaacata aagaacgttc ctaaagataa tataccacct gtcacactat ctaatccata
    13441 tgatttagct agatccgaac ccataacaaa agttgcataa atagccatca atcccatcgt
    13501 catcctaaaa ggtaaaacaa tcgttgccga ataaggggca ataaattcat tccatccagg
    13561 aaacggtaaa ttgataaaga ccataaaaaa tgtcccaatc aaaatcaatg acaatgttga
    13621 aacaacccca ttacgaattg ctaataaatg acgctgtgta ccaatttttg ccattggtgg
    13681 gacaagtttc tcttcgaccc atttcatcag cttttccact aaaaccactc cttttcaata
    13741 aaatatgaac cattcattgc atgacaacgc aaagaatgtt cataactaat tatataatta
    13801 agaaatttta tttcaatata ttctcttaaa taatcaaatt tatttttaag aatcctgaaa
    13861 ataagttttc taaatcatag gagcaacaaa aaaattcgat aattaacaaa aatcaaaatg
    13921 attaaatcta gtgattgaaa cttatcattt caaaaaaatt ttgtaaattc acccataaat
    13981 atcaccctat ttaacttttt tcatcgtaca ctaaaattca aaacaactat ctttaatctt
    14041 tacttcttgg ttttgtttta ataaatttcc ttcaaaaatg cctggagaaa ctacaatgat
    14101 caccgtatct ttttgtgctt gctccaactt cttcaaatct ataatagcta acagtgtccc
    14161 ttcttttacc tcctggttac tttcaacccg tatctgaaac ggacttcctt cgagttcaac
    14221 tgtatctaaa cccatatgga tcagtatttt tctgccagat tcactttcga tcgttatggc
    14281 atgtcgggta ggaaatatat tatcgattat tcctttaact ggcgcatgga tatatccatc
    14341 atgattcgtt atagcgtatc caactcctat catttttgaa gaaaagacct cgtcttttac
    14401 tgctgttaat ggaataattt gaccactagc tacagctttt agaatgtttc ttgttttaaa
    14461 gaaatgcact ttttatcacc tctactttaa tgctggccaa tattttttgt ttactttgat
    14521 catttcatct agtatttttt ttgcgactct ggcatttggt acggtttgat tcaatgtaaa
    14581 tgcttgtaaa gctttttgat aagaaccttc aaagtaagca tctactagta acttctctgc
    14641 tgcaacttgt gcctccatca atcctttatg aaaatcactg attggttttc ttagtgtaat
    14701 tgtctccaca ccagttgcac caacatatgc cggtatttca acaactgcat ctgaccgtag
    14761 attcggaatc gccccttgat taggaacgat tagcataaag cgacgacgat catcattcaa
    14821 caaggaaata gctatatcga cgatatattg tccatgctcc ccaaaattaa agttcaatac
    14881 ttcttccaca ataccgcggc gtattttatc agccatttct ttggtatttt tctctcgtcc
    14941 atccatgacc atattagcac gtgtatactc tttgtcagta tgctcaacga ccatatcagg
    15001 atataagtaa tactctaagt aattattcgg gatattactt ggaaaatttt tcgtgatgac
    15061 tgacatcatt tgaaaggttt tttgccaagt tttgtctcct atattaaaat cggcgacttg
    15121 catttctttt gttattagtt tttcaataat ctctggcata atttctcgtt gcaattcttt
    15181 atcataaatc gatgtatacc agccaaagtg gtttaaacca taatacgtaa cgatccaatt
    15241 cttacgatca taaccgtaat tcactgcaat cgtttcttca attgaaatag tcatatcaca
    15301 ggcattaatc atttttacat tcggatattt acgacgaaca gcttcagaaa cgatcgactc
    15361 tggatttgta taattcaaaa tccatgcttt gggggcatag tcttgtatat gatcgacaat
    15421 ttccaataaa cctttgattg agcgcatccc ataagcaaat cctccgagtc cacacgtttc
    15481 ctgtcctact aatccatgtt taagtggaat cttttcgtcc ttttctcgca tctccaatcc
    15541 tccaacacga atttgtgaga aaacaaaatc gcatcctgta aaagcaagct ttggatcatc
    15601 cgttgcacga atgcgaatat ttgaaaaacc ttttttttca gcataaattt aacaatcaag
    15661 tacatatcca tatttctttc ttcatcaata tcatataaac gtatttcaga taatggcaac
    15721 cgtttttcat tgttcaaaat ggcttgaacg attcctggtg tatacgtact cccgcctcca
    15781 gctatagtga taatctgttt tttcatcatc atcttttcct ttctattctt ctaataattt
    15841 attgaattct gccataacat aagtcacttc taagccgatg ataatttgat aatttttttc
    15901 agttggttta atgatcccgc ttatccctaa ttgcttgatt cgctgttcct cgaccatggt
    15961 gggatccact acctctaccc gtaggcgtgt attacaacta tagacatcca ggatattggc
    16021 ttttcctcca aacgcttgta gcatttttgt tgccatatat tcataatttt tacttgctaa
    16081 ccctaactct gtttcttcta aggttacttc attgccaaac tctgccttag cttcacgtcc
    16141 taatgtctga atgtttctct tattgatcaa ataataaaaa gtaacgtaat acaaggcaaa
    16201 aaagaaaatt ccgattggaa gaatcaaaat agcattggta gcgattcgaa aattgatgag
    16261 ataatcaaca atacatgctc cgaatgtaaa accaattcgt atattgaata agtaacagac
    16321 aatccctgct aaaccggcaa aaagtgcatg gatcacgtac aacataggag aaagaaacat
    16381 gaaactaaat tcaacaggct cagtgatatt tgcaataaat gaagttcctg caccgcttcc
    16441 catgattcct ttgaccatct ctttattttc tttataagct gctttataga tagctagaca
    16501 tatagctggt ataccaaaca tcattactac aaaaaaacct gataaaaaca gtccagcctg
    16561 aggatctccg ttgataaagc gtgtcatctc tcctctgaaa acttccttgc taggagatgt
    16621 atagcttcct aaatcgtaat aaatatacgt attcaacaca tggtgcagtc caaaggggat
    16681 cagcaaacga ttcaaaaaca taaatatccc cacacctaat gcccccatat caacgagcag
    16741 ttttgcaaaa ttatcaatcc caatttggat gagcggccag ataaagccca aaaaaatagc
    16801 tgcgattgtt tgtagaatca tcaccatagt caatgggaat ttttcgcccg caaaataaga
    16861 aaaaactact ggtaattttt gttctttaaa gcgattatac gtccatgccg ctactaaacc
    16921 ggaaataatt ccaccaaaaa tccccatatt cacttctggg tccatgattt ctaagccttt
    16981 tttcaaggta gcaatcgcta aaaaaccagt aagtgcaggt attcctttgt ccttattttt
    17041 gacaaaaccg attgcaactc ctatagcaaa taagatatcc aagtttccaa aaacggcatt
    17101 tccagctgca ccaattactg ggatgttcag catatcatca gctgataaac gcatgatcaa
    17161 tcccgctaat ggcatcgctg caactggaag tagcatcgct cttccaagct tctgcacatt
    17221 tgatttaaca ttcattttta ttcctcctct attaaatatc ctcatatgtt actaactcaa
    17281 tcaaaggatc atttttcact ttttgagcaa atgctgaatg aattaaaaat tcgacttggt
    17341 gagtacgagg atacacaaaa cttgaaccat ttaacaattc ctgatccaaa tacgctgcgt
    17401 gacacatgac ttcgatcgtt ttatcttctc tcaatatcat gagtaaactt gccaaatatt
    17461 cttccacact cgtattgatt tgtcgttttt tttcatcagt ttctcctacg acatcgaaac
    17521 aaggctcaaa ataatcgaca tgacgaactt catcttttcg ttcaaagttg ctccgaaccg
    17581 gcaaatcata tttttttgct aatgtaacaa ctacctcctg gttttcatcc aaagtatgag
    17641 tatgatgatg actgtctaaa tgagttggta tgatccccgc atgataaatt ttttgaatct
    17701 gagcattcca ttcctgatac agttgatctt tgtcaatgtt aaatggatgc tgataataag
    17761 ataaggatct gaactctccg ctttcgataa gagtatcgac agttttgaga agtggtttgc
    17821 cacacgtcaa tgttaaatgg actcctacac ctagcctagg catttccttt cttagtttca
    17881 cagcgtgctc gaaacccggc atatttgcca tcaatgtagt tgatgtcaaa attcctcgct
    17941 gataagcatc cataatccca taattcacac catggctata gccaaaatca tccgaattaa
    18001 aaatcacttt tcccatttca ttctccttct tttttctact aaaataggcg caaccaaata
    18061 atcatagtcc atttactatg tgtcatttgg ttgcgcctat agatagttac gcccttattt
    18121 taatagattc gtgctagatg aattgccaaa tagatgattt cattttcttg aatggcaagt
    18181 tgaaattgct gttcgatgat atctttaatc tttagtgctg tacaatacgc tttgctatgt
    18241 ttaaatgttt cagtaaaaaa accaatattt tctactggcg tttcttcctg ataaatcaag
    18301 cgtttaacca ggaatttgat atgaaccatt aagcgatgat aagtcagtga ttctttatca
    18361 taaacgtttg aataggattt ttctagatgg gacaaaatcg tggtcgtcat ttctactatt
    18421 tttaagctct ttaaactatt aggctctcct agctcagcat taatgatatg catagtgatg
    18481 aatcctactt catttgaccc taactcggtt tgatatcgat gattgattcg ctcgaccact
    18541 tctattgcta tatcatattc atttggataa aggaatctca tttctggcaa cataattgct
    18601 gtgacatctc tatcttctct ttttcgttga atagcaaaat aaatatgatc tgtcaatgta
    18661 atatagatat ttgaatctaa tggagaggag atcctagctg ttatcagttc aatcacttct
    18721 tccgcaaaat ccataaattc gattggaatc tgcgagacta tctcactgaa tcgtttgatc
    18781 ttttctttag aatctaatac aaataatttg tcagcatcct caacatcaaa tggcttactc
    18841 actttagcag aaaagccaat ccctttcccc atcgcaattt tttctattcc atcgtcatcg
    18901 atcaatacag cattatgatt cagctttttc atcacataca ccgttaattc acctccacta
    18961 tatgataaaa caaaacaact tgcagactcc ttcatacata tttttgtctc caaacaattt
    19021 ttaaagacaa aaaacgacct aagaaagaac cctttcttag gtcgtgccta attgaatagt
    19081 agcaccctac ataatttaca aaaatagttt aacacataat aaaagcgtta tcaatatctt
    19141 ttttactcgt tttatgataa tacttgtatc gaattgattt ggaggtaatt acataaaaac
    19201 aaaaaaaata tagcaactct ctataagaaa gttgctatat tgataattat accggcggcc
    19261 ggggtcgaac cggcacgtcc tcaacggaca ctggattttg agtccagcgc gtctgccaat
    19321 tccgccacgc cggcaaattt aaaaataata actggggtag ctggattcga accaacgcat
    19381 gagggagtca aagtcccttg ccttaccgct tggctatacc ccaagaataa agggcgaatg
    19441 atgggaatcg aacccacgaa tgccggagcc acaatccggt gcgttaacca cttcgccaca
    19501 ttcgccatca taaaagatgt tatttaattt ctcaataaaa aactaagatg aagacatctt
    19561 agtcaatacc ggcggccggg gtcgaaccgg cacgccctca acgggcactg gattttgagt
    19621 ccagcgcgtc tgccaattcc gccacgccgg caagttgatt tattagtact aaggcggtaa
    19681 ccggatttga accggtgatg aaggttttgc agacctctgc cttaccactt ggctataccg
    19741 ccattatact attatcaatc tacaaaataa agaataaatt atagaaactg gggtagctgg
    19801 attcgaacca acgcatgagg gagtcaaagt cccttgcctt accgcttggc tataccccaa
    19861 gaataaaaag ggcgaatgat gggaatcgaa cccacgaatg ccggagccac aatccggtgc
    19921 gttaaccact tcgccacatt cgccatggca ggggcagcag gaattgaacc cacactaacg
    19981 gttttggaga ccgctgttct acctttaaac tatgccccta taaaatggag gagagtggat
    20041 tcgaaccact gaaccctaag gaacggattt acagtccgtc gcgtttagcc acttcgctac
    20101 tcctccatgg tggcgcggga cagaatcgaa ctgccgacac acggagcttc aatccgttgc
    20161 tctaccaact gagctaccgc gccatatttt aaaattatta attgaataac aagaacgacg
    20221 gttccgacgg gaatcgaacc cgcgatctcc tgcgtgacag gcaggcatgt taacccctac
    20281 accacggaac cagttcatta tggaggttaa cgggatcgaa ccgctgaccc tctgcttgta
    20341 aggcagatgc tctcccagct gagctaaacc tccaacattc aattaaaatg acccgtacgg
    20401 gattcgaacc cgtgttaccg ccgtgaaagg gcggtgtctt aaccgcttga ccaacgggcc
    20461 aggtaaattt gctacggaga gtaagggatt cgaacccttg agacagtttg caccatctac
    20521 atgatttcca atcatgctcc ttcggcctct cggacaactc tccagagtga aagaagctca
    20581 atactctttc tcaaaatgag
//
LOCUS       DAXLPQ010000047        19851 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.047, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000047 DAXLPQ010000000
VERSION     DAXLPQ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.047"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..265
                     /locus_tag="ACF3UO_002045"
     CDS             <1..265
                     /locus_tag="ACF3UO_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658017.1"
                     /translation="GLTNFEILLELKNEIIRLNMEDDLSMTKFQNYSKSKHLPSVYTI
                     MRRTNKTWEELMSEIGYDYKEIKIKKQRNNLRCRSKKICSRYE"
     gene            694..4287
                     /locus_tag="ACF3UO_002046"
     CDS             694..4287
                     /locus_tag="ACF3UO_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3658018.1"
                     /translation="MIRNKKLCLKVALLAVFCQVFFLVGSLTTQAEEITQGTTVSQVS
                     PTSNEVEVQSDLPKETAKEEISTEFVPPTEAPSMNEKSVLDETIGKSQQPGDSPVVAE
                     EIPIETPEVQTIFEKENSSEKSCSTVINEGTESVQSEDSKEATTPIELTKEEMNSNTS
                     LSSEKEEKTALSTESHEPELKKVEESGDTQKEKIKKEAVSSTSSKEVTLIVPQTARSA
                     RVRRATNTAVLGGRKIDWGENIGVISSANNPNFTLNYMVRFEINGQVAFCIEPGVAAA
                     EGQVYTATALENYLKDLNIRKKTSLISYLGYVTSKDKSDEQYIAAQFMIWEVLGTKIP
                     IKNIRIDYDRRKAEIQRLLNNFDVRATFHNQTHTVKIGETLKVKSGNDFLQRVKDIQK
                     PKGVNVSIHDNEVWITITKESPEKAKIHFNQIEALGVPLAYRRPGAQTIGVLNPFVPG
                     DSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQANGKKIKEITLKNING
                     KVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNTIAKDQVIKGTIDLV
                     KVANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTVVFDTY
                     ILSETKGKEGYKLFEPFEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKVIALAG
                     TQFKIWDKYANNGKGGYVSMALPNDTEVSDIFTTNEKGYFVTTDTLKYGKNRYELREI
                     KAPEKYVLNKTPYVFSVTDDTNTIQLIYFANRLAKANVEVFKYDTSTNFDQKTAIAGV
                     EFDLFKKDETGTTFVGTFKTDKKGKINVKDLLVGDYFFKEVKPLAGYLALDKDVPFTV
                     TVDKDGTVIALEVENKRIPPKIGTTAIGKYTNQQKVTPLKKVTITDTVKYSNLIIGKT
                     YTVNGVLMDKEESITAGKDVPLLVNGKQITASKVFVAKNPNGMISLDFVFDASALAGK
                     EIVVFENVYRDGRLVASHTDIHDKGQTVRIVNPMIHTKATGQNGEKQLQALPNQKVKE
                     LVQLNDLIVGQTYKVLVQGYITPDGVKLDGTSAEKIFKADKTTLEFLFEFLVDGRKLA
                     GKGLSFAEWLEAQSEPKDENDYEVRFEQIANHNVDLKSEDQTVYFVEVPKVPEPKIPE
                     KSQPFKEVKQASVVPMLPKTGSEDTVLWMIIGVLFVLAAGLTFYELRKVKD"
     gene            4387..5325
                     /locus_tag="ACF3UO_002047"
     CDS             4387..5325
                     /locus_tag="ACF3UO_002047"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3658019.1"
                     /translation="MKKKERKKRMKKLFFACLFSSVVLAGGINVFADEIGITPVTPPV
                     IEETTPVVPIPDISKIDESVPDQPTPVDPDISSEVTEPTTPVVPDITENSENETPVVS
                     PSTGETTNDKDTTPTTSESYSGTSSVDNDSKIDDFSSSSTTIDTPKETEKKNDLGAPK
                     NLTPENHIKTVSEKEMTVSVSSDGKIVQGTGTEKSIPIVTSNLEEINHVPTSETPLQV
                     ATGQAIVGVQDGVPLVQDNQGNLVEDLSIPVKKLPSGNIEIKTIDGKTKVLPKTGEEL
                     QISLTILGSLLTAVTGGIFYGKKQWRHLRHMFKKTI"
     gene            5344..5694
                     /locus_tag="ACF3UO_002048"
     CDS             5344..5694
                     /locus_tag="ACF3UO_002048"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658020.1"
                     /translation="MGLSYVAISQEEVLGKCFNQKHVGSTGERDHRGNMKKVEWEIFQ
                     MNSEKMGEIEVRVAVGGAPKAMRYNAEVLLANPRISRRADVRNIGNDGETNKIARNRF
                     YLLVDRVEVKGGNN"
     gene            5694..6125
                     /locus_tag="ACF3UO_002049"
     CDS             5694..6125
                     /locus_tag="ACF3UO_002049"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF961 family protein"
                     /protein_id="HFD3658021.1"
                     /translation="MTLEFDQGIVPGLVKETLGEIYFVKAQRPRMLYEDNENTGEIKE
                     RPVEFSSATQETMFVVNFPPKTNLDGLSFGDVVELEEVEFRFWISIDRESMSNRAEND
                     LKVSALRYKKTGKNVFQTSSSTRATYVKEKQDSNKESAKKE"
     gene            6393..7712
                     /locus_tag="ACF3UO_002050"
     CDS             6393..7712
                     /locus_tag="ACF3UO_002050"
                     /inference="COORDINATES: protein motif:HMM:NF013727.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFD3658022.1"
                     /translation="MFQYKGIRIRNRHKYASERFIFYLMLPVLLLMSGFFSLFYTTIT
                     WEWCCIYWIIAFGLAGLFAYMCLYFYFYNVYQRLVHKGKLAKMIHSRRLILERVLKNG
                     RRKVVYYPKIFYHYKNGLIHVRLPLDLGPFQDRFNEMAGQLEEAFFCDLVEEQREKNY
                     ICYTFLYDVEKNRIGIRDITVKDGIITLMKNVQWAFNKAPHAIIIGSTGGGKTYFIMS
                     LIYALLPYGTFDICDPKRADLASLEKIPIFKDQVFYGGGILSCLINLAKETANRYDFL
                     REQPEYELGYDYTYYHLTPHFLVIDEWAAYYASLDTKEKKKAMGCLNQIALMGRQCGV
                     FLILGTQRPDTKYLDGAIRDNFGLRVTLGRVSKAGYKMIFEHTVKSLFNKPIKGRGYI
                     DSGTDQVREFYAPFIDITRFNFFAEFKQLSDQLMAEKIKETKEGKNV"
     gene            7705..7869
                     /locus_tag="ACF3UO_002051"
     CDS             7705..7869
                     /locus_tag="ACF3UO_002051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658023.1"
                     /translation="MYEEIPATCGTRLGIKDLMIDSFLAIVFSEKRLSFFINKKVENR
                     WRVERMYPTS"
     gene            8408..9583
                     /locus_tag="ACF3UO_002052"
     CDS             8408..9583
                     /locus_tag="ACF3UO_002052"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3658024.1"
                     /translation="MDGTQLKQMRLSRNLTQKLVADTLGWPQSFLSMIENDQRSCSKE
                     QEEALCEFYANFSSFTSLEIKFDYVRVRVPTNDTKTVVEEILGMDFNSFFYAETRLYG
                     YIEMYQKGMIRVLNSKKGDDKGVLIELSGQGCRNYESVLDERNDSWYQFFTRCVSFNG
                     VSRRIDIAVDDFEELFSLHEFAQKLNRGEFDSKFRTWRFQEEKQLLDNLSSGLSVYLG
                     SSQSLMYFCFYQKNYEIAKKQKLPLEEVEVKNRYEIRLRDAKAVSFIEQYLNKVDFSD
                     LTMGILANQLIMFEGEKNTNVWKPWGKLIQNVGKVNLTVTPEKPNYNRKLMYLKTQPA
                     RTMKIVKTVDEILGLNRFGEILEETELREQDEKIVEDEVRAVYEYIQENPDAIHYLL"
     gene            10088..10285
                     /locus_tag="ACF3UO_002053"
     CDS             10088..10285
                     /locus_tag="ACF3UO_002053"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658025.1"
                     /translation="MGQYFLTGVWYVLKLVIILGIAYICFRILLSGEGMPTPKDFIIS
                     VLNFVADQIQVIIHWAQQRFG"
     gene            complement(10682..11230)
                     /locus_tag="ACF3UO_002054"
     CDS             complement(10682..11230)
                     /locus_tag="ACF3UO_002054"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658026.1"
                     /translation="MSILQPFGEPIERTEFIQHYMKLFVQVIKHTHQIDEFYSKEIEY
                     LLAEKQKIALLYDYFVEMYDRAPDYFYLSDTLTTNFLAKEHLFASHTKNLMCVEHFVN
                     TYLHLLKIQKICTFEAFQTDYLFILDREAYHAKLAFEKQNQAIEGYPELRIQNNSFLQ
                     QRLLKQLINGFHQRNKAYQKDQ"
     gene            complement(11286..11579)
                     /locus_tag="ACF3UO_002055"
     CDS             complement(11286..11579)
                     /locus_tag="ACF3UO_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658027.1"
                     /translation="MLRTNAIPIVDSYDRNTNNYLGSFEQTDENILNYVAGLSPFESV
                     RLVEHTTDTLILTTIGYFFDQVSDQQWLQQILPKLIAKQTGKSTIEAVKIFFY"
     gene            complement(11772..12113)
                     /locus_tag="ACF3UO_002056"
     CDS             complement(11772..12113)
                     /locus_tag="ACF3UO_002056"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658028.1"
                     /translation="MKANTPYKVGDIFYSSWGYEQTNVTFWQIIKLTKKTAWFRPIKK
                     QTVKNYTSMSGETMPIPNEFIDYPLARTKDSIVRKRINPALYPNELYGNRSWDTFYRY
                     DNQPVYESSYY"
     gene            12614..12766
                     /locus_tag="ACF3UO_002057"
     CDS             12614..12766
                     /locus_tag="ACF3UO_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658029.1"
                     /translation="MKKKGIPYSPKPRNAFERGLFKYFEGERDQEEKEKNQKKKSSQE
                     KENIEK"
     gene            12788..13255
                     /locus_tag="ACF3UO_002058"
     CDS             12788..13255
                     /locus_tag="ACF3UO_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658030.1"
                     /translation="MKKSLIVLIVGLSIFGSVLFIGNSLFSNKDVTEQSPASTTEEVS
                     PELLLETDVLDTKKPETIPSENELYQGDLSFEYADPEKPYVLTIRFIDKANHEYVGPD
                     KKPLKREKELILGKAKGVVHVVVKANRSMLTHIQKLKDIQVSMTLNERNEKTE"
     gene            13501..16464
                     /locus_tag="ACF3UO_002059"
     CDS             13501..16464
                     /locus_tag="ACF3UO_002059"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3658031.1"
                     /translation="MLKKVLRFGVCISIWLVTSSTFVPSMIAVADSVAIQETIASDSE
                     GEEKLTERSDDASDGQTEKVEVQKTETTQTTVSSSSDESSDLTQSSEETAPEEVDEST
                     EESSDPQEQTISHEEETKEAVDSSTIDFEGTRSSESFGKHTSPSIDKPNEKIAEPVSS
                     NEGAVVSRRSRRDLSAVSSNHPEEEPVVAFDEKAFDAAIDQYIDHATEEELGLVINSS
                     NEKELADALEYLLLNQLDESFGVEELDELKKFLTADEIERLENESSLETFEQLLTQYY
                     NDREQKLEEGAAFSDFFLASTDEEIDRMLEVKDEQALEQVISEISASRNSQTSGKRNK
                     RFLVIPLLVKGAMLVIGAGVAAYSSHQFYKTMEAQRAEKKRMVERWRYHEQQAQKRHQ
                     AAQQARAKAVARAKLQAAARAKAQATQRARAQAAAKARKQAQNWAKQQAAARARAQAA
                     ASARRKSNASYVPPVTRPKPVIKAQPKVPAKPVAKPVTKPTSPAKPKPTTTPKNTMHQ
                     VRAGESVWSISHKYGISMNDFIKWNKIKNNLIHPGQQVIVKQPASTSKPVSKPATKSS
                     TPATYKVKAGDSVWGICEKYGLSVSKFVQWNKIKNNTIHPGQVMHLQEPKPASKPAPK
                     TSPTTNTTYTVKAGDSVWLIANMHGISMNDLVKWNKIKNNTIHPGQKLTVKQPVSSGK
                     TTTKVPASTNPVTHKVSYGEPLWLISSKYGVTVDELRKQNGIKGDLIHPGQVLVVKKG
                     MTTSHSTPAGKSGTSYTVKAGDSVWLIANRYDVSMDDLVKWNKIKNYTIHPGQVLTIQ
                     TIVSTPAKPAITTTPKVESKPAITTTPKVESKPGVTTTPKVDEKPVITTLPKVKEQPV
                     VTTVPKTESEVLVEKASGSTGTVWDDIKGTQPPREGTTIPKSFEIIVNGEKLWVNPNG
                     TKHMVEYSTRNLSHGQKLTEQQLLRSFQGAVEQATSTGIKFETKIIIDNWELIFSPAR
                     EAGQLPVIKHAVYLP"
     gene            16483..16995
                     /locus_tag="ACF3UO_002060"
     CDS             16483..16995
                     /locus_tag="ACF3UO_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016617327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658032.1"
                     /translation="MKIKSYEDKLVKDDIEVDYYVPITVSFPENDDKYNLGEFYYYRF
                     VNEYESFVEIKINSVTQKIVEVVFTSINDIEDSNLFIGEYAEKNPVIQTDIFDENSII
                     TKESGFKISREHKKLCFKLDKEKMDSVVKMSNHVSLFLNEDSEIIGLEFSSFSDNEWA
                     ELNESIKSTT"
     gene            17517..18584
                     /locus_tag="ACF3UO_002061"
     CDS             17517..18584
                     /locus_tag="ACF3UO_002061"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3658033.1"
                     /translation="MAKPSTPATYKVKAGDSVWGICEKYGLSISKFVQWNKIKNNTIH
                     PGQKLTVKQPVSSGKPTTKVPASTNPVTHKVSYGESLWLISSKYGVTVDELRKQNGIK
                     GDLIHPGQVLVVKKGMTTSHSTPVGKSGTSYTVKAGDSVWLIANRYGVSMDDLVKWNK
                     IKNYTIHPGQVLTIQTIVSTPAKPAITTTPKVKAKPAITTTPKAESKSGVTTTPKVDE
                     KPVITTIPKVKEQPVVTTVPKTESEVLVEKASGDGSRLDINIKNFEIKNKHLNSSTAK
                     RARKFNVSSAEEANKIVQDALKNGKLVEAIPNGVGSQGQNSFSSIIDTGKVIGTKGET
                     HIKIVYDELKNVWTTYPVPKP"
     gene            18601..18987
                     /locus_tag="ACF3UO_002062"
     CDS             18601..18987
                     /locus_tag="ACF3UO_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658034.1"
                     /translation="MIDKQITNILQSYKKQQIFKIEDFLLSEIDEDNLQETIDFVVSD
                     DVSKKINFSDELYDGNEYEGVFLEGNQYLLSSSEGKVMIIDMLSEAHGVNIKDTRVQF
                     DEEKFIKLITNKKEILNWIKNYKVDK"
BASE COUNT         7162 a         2960 c         3930 g         5799 t
ORIGIN      
        1 gggattaact aattttgaga tacttttaga gcttaagaat gaaataatta gacttaatat
       61 ggaagatgat ttatctatga caaaatttca aaactattca aaatccaaac atcttccatc
      121 tgtatataca attatgagac ggacaaataa gacatgggaa gaattgatga gcgaaattgg
      181 gtatgattat aaagaaataa aaataaaaaa acagagaaat aatttgcgtt gtagatcaaa
      241 aaaaatatgt tcaagatatg aataaacaaa gtatttttca gcatattttt atctgtacca
      301 ttattttaaa tatccatagc agtttattca tgatttatga ggtttaaaat acaatactga
      361 attcactgct tattttcatg ttactgctta aactttgtat tttaatagaa aatagagatg
      421 tgaacgaaaa atatttattt ctattacaaa aggtaaaaaa tttgatttaa aagctaaatg
      481 tacagatgag ttttgaattt ttctccttca aattcaaaat gagagtagta ggtatgatag
      541 aaatatatca aatattaaga tagatacaat atgcataata ggctatgctt ctttagattt
      601 tttgattaag aacacaataa atagtttacg tcgatactta ttaagttatc gacgtttttt
      661 ttataaaaaa tttataaaag gaggtttctt gatatgataa gaaacaaaaa gctttgcttg
      721 aaagttgctt tattggcagt tttttgtcaa gtattttttt tggtaggctc actgacaaca
      781 caagcagaag aaataactca aggaacaact gtttctcaag tttctcctac ttcaaatgaa
      841 gttgaagtac aatccgattt accaaaagag actgccaaag aagagatatc gacagaattt
      901 gttccaccaa cagaagcacc ttcaatgaac gaaaaaagcg tactcgatga aaccatcggt
      961 aaaagccaac aaccaggaga tagtccagtt gtggcagaag aaataccaat agaaacacct
     1021 gaagttcaaa caatttttga aaaggaaaat tcatcagaaa aaagttgttc tactgtaata
     1081 aacgaaggaa cagaatcagt tcaatcagaa gattcaaaag aggcaacgac tccgattgaa
     1141 ttgacgaaag aagaaatgaa ttctaatact tcactttctt ctgaaaaaga agagaaaaca
     1201 gctctttcga cagaatccca tgaacctgaa ttgaaaaaag ttgaggaatc aggtgataca
     1261 caaaaagaga aaataaaaaa agaagctgtt tcttctactt cttcaaaaga agttacattg
     1321 attgtaccac aaaccgctcg aagtgcacgg gtgcgacgtg caaccaatac agcagttttg
     1381 ggtggtcgga aaattgattg gggcgaaaat attggtgtta tttctagtgc caataatccc
     1441 aatttcactt taaattacat ggttcgtttt gagattaatg gacaagtagc attttgtatt
     1501 gaacctggtg tcgcagccgc agaaggtcaa gtttatacag ctactgcttt agaaaactat
     1561 ttgaaagatt taaatatacg aaaaaaaaca agcttgatct cttatttagg atatgtcaca
     1621 agcaaagaca aatccgatga acaatacatt gcggcacaat ttatgatttg ggaagttttg
     1681 ggcacaaaaa ttccaattaa aaatatccgt attgactatg atcgtcgaaa agcagaaatt
     1741 caacgtttgc ttaataattt tgatgtaaga gctacttttc ataatcaaac acatacggta
     1801 aaaattggcg aaacgttaaa agtaaaaagt ggcaatgact ttctacaacg tgtaaaagac
     1861 attcaaaagc caaaaggtgt taatgtatct attcatgata atgaagtatg gattacaatc
     1921 acaaaagagt caccagaaaa ggcaaaaatt catttcaatc aaattgaagc attaggcgtg
     1981 ccattagcgt atcgtcgtcc aggtgctcaa acaattgggg tgctgaatcc ttttgtacct
     2041 ggtgactctg ttgtcaattt gaccattttg aaacaaggaa acattcgcgt ctttaaagaa
     2101 gatgcagaaa ccggtgtgaa agcacaaggt gcagcttctt tagaaaatgc agtgtatggc
     2161 ttgtatcaag caaatgggaa gaaaatcaaa gaaattacat tgaaaaatat caatggcaaa
     2221 gtacaggcag aaatcaaaga tcttgatcct ggtaaatatg ttttaaaaga gatcaaagca
     2281 ccaaaaggtt atgtactttc tgatgaagca attgaaatcg tcgttgaacc tggaaaaact
     2341 gtcaatacga tcgcaaaaga tcaagtgatc aaaggaacca ttgatttagt caaagtcgca
     2401 aataaagatt tagtcgattc aaccaatcca gacaacaaac ccaaattagc tggtattgaa
     2461 atctctttga cgtcaaaaac aactggaaaa gtggtgaaaa cagttgtgac agataatgat
     2521 ggttacgcta cttttggtaa aaataccgtt gtctttgata cgtacattct ttctgaaacc
     2581 aaaggaaaag aaggatataa actatttgaa ccattcgaag tcacaatttc tgaaaatgga
     2641 caaaccttcc attatgtttt agaagacaaa gtaatcgaac aacgtcttaa agtggtgaaa
     2701 gtggatcaag aaacagggaa agtcattgct ctagctggta cccaattcaa aatttgggat
     2761 aaatacgcaa acaatggtaa aggtggctat gtatcgatgg cattaccgaa tgatacagag
     2821 gtttcagaca tatttacaac aaacgagaaa gggtactttg tcacaacgga tacattgaaa
     2881 tacggaaaaa atcgttacga gttgcgagaa atcaaagcac ctgaaaaata tgttctaaat
     2941 aaaacgcctt atgtcttttc agtaacagac gacaccaata cgattcaatt aatctacttc
     3001 gctaaccgtt tagcgaaagc caacgtagag gttttcaaat atgatactag tacgaatttt
     3061 gatcaaaaaa cggcgattgc tggtgttgaa tttgacctat tcaaaaaaga tgaaacaggc
     3121 acaacctttg ttggtacatt caaaacagac aaaaaaggta aaatcaatgt gaaagactta
     3181 ttggttggcg attacttctt taaagaagtg aaaccattag cagggtatct ggccttagat
     3241 aaagacgtac catttactgt aacggttgat aaagacggta cagtgattgc actagaagtg
     3301 gaaaacaaac ggattccacc taaaattggt actacagcta tcggtaagta tacaaaccaa
     3361 caaaaagtga ccccattgaa aaaagtaacg attacagaca ctgtaaaata cagtaatcta
     3421 atcatcggaa aaacttatac cgtcaatggt gttttgatgg ataaggaaga atctatcaca
     3481 gcaggaaaag acgtaccgtt gttagtaaat ggtaaacaaa ttaccgcaag taaagtgttt
     3541 gtcgcaaaaa atcctaacgg aatgatttcc cttgactttg tctttgatgc tagtgcatta
     3601 gctggaaaag agatagtcgt atttgaaaat gtctatcgtg acggacgctt agttgcgtct
     3661 catacagata ttcacgataa aggacaaacg gttcgtattg tgaaccctat gattcataca
     3721 aaagcaacag gtcaaaacgg cgaaaaacaa ttacaagctt taccaaatca aaaagtgaaa
     3781 gaattggtac agttgaacga cttaattgtt ggtcaaacgt acaaagtgct cgtacaaggt
     3841 tatattacac ctgatggtgt gaaattagac ggtacaagtg ctgaaaaaat tttcaaagca
     3901 gataagacaa ctttagagtt cttatttgaa tttttggtag atggacgtaa gctagcaggc
     3961 aaaggattat cttttgcaga atggttagaa gcccaaagtg aaccaaaaga tgaaaacgat
     4021 tatgaagttc gatttgaaca aatcgcaaac cacaacgtag acttaaaatc agaagatcaa
     4081 acggtttatt ttgtagaagt tccaaaagta ccggaaccaa aaattcctga aaaatcacaa
     4141 ccttttaaag aggtgaaaca agcttcagta gtaccaatgt tgccaaaaac aggatcagaa
     4201 gatactgtat tatggatgat cattggtgtg ctatttgttt tagcagcagg tcttacattt
     4261 tacgagttac gcaaagtcaa agactaagta ggacaaacaa gcggttagat gcctaatcgc
     4321 ttgtttggtt ttaaaaaagt tattgcataa gtaacctttg aaaagataag aaatgatctt
     4381 tgttttatga agaaaaaaga aaggaaaaag agaatgaaga agctattttt cgcatgttta
     4441 tttagttccg tagttcttgc tggtggaata aacgtttttg cagatgaaat aggtattaca
     4501 ccagttacgc cacctgtgat agaagaaaca acacctgttg ttccaattcc agatatttct
     4561 aaaatagatg agtctgttcc ggatcaacca actcctgttg atccggatat atcttcagaa
     4621 gtaactgaac caacaacacc tgttgttcct gatataacgg aaaattcaga aaatgaaaca
     4681 ccagttgtat cgccttctac tggagaaaca acgaatgata aagatactac accaactacc
     4741 agtgagtctt attcgggaac tagttcggta gataatgatt caaaaataga cgattttagt
     4801 tcttcatcta ctacaataga tacaccaaaa gaaacagaaa agaaaaatga tttaggagct
     4861 cccaaaaatt taacacctga aaatcatata aagactgtat cggaaaagga aatgactgtt
     4921 tcagtcagtt cagatggaaa aattgtacaa ggaacgggta ccgaaaaatc aattcctatt
     4981 gtgacaagta atttagaaga aattaatcat gtcccaacat ctgaaactcc tttacaagta
     5041 gcgactggtc aagcgattgt tggggtacaa gatggtgtac cacttgtaca agataatcaa
     5101 gggaatttgg tagaagattt atccattcct gtaaaaaaac tacctagcgg caatattgaa
     5161 atcaaaacaa tcgatgggaa aacaaaagta ttgccaaaaa caggtgaaga acttcaaatt
     5221 agtttaacta tccttggttc tcttttaaca gcagtaaccg ggggcatttt ttatggtaaa
     5281 aaacaatggc gtcatttgcg tcatatgttt aagaaaacta tttagtaagg agagagaata
     5341 aaaatgggtt tatcttatgt tgcaattagt caggaagaag tattgggaaa gtgttttaat
     5401 caaaaacacg ttggctcgac aggtgaacga gatcatcgag gaaatatgaa gaaagtagag
     5461 tgggagattt ttcagatgaa ctctgaaaag atgggagaaa ttgaagtgcg tgtagctgtc
     5521 ggtggtgcgc ctaaagccat gcgatacaat gcagaagtgt tactggcaaa tcctagaatt
     5581 tctcgtcgag cagatgtacg aaatattgga aatgacggtg aaacaaacaa aatagcacgt
     5641 aataggtttt atttgttagt cgatcgtgta gaagtaaaag gaggaaataa ctaatgacac
     5701 tagaatttga tcaaggaatt gtcccagggt tggtaaaaga aacactagga gaaatctatt
     5761 ttgtcaaggc acaacgtcca cgtatgctgt atgaagataa tgaaaacaca ggagaaatta
     5821 aagagcgtcc agttgaattt tcaagtgcta cccaagaaac aatgttcgtg gtgaattttc
     5881 caccaaaaac aaatttggat ggattaagtt ttggcgatgt ggtggaatta gaagaggttg
     5941 aatttcgatt ttggatttct attgatcgcg aatcaatgag taaccgagca gagaatgatc
     6001 tgaaagtatc tgcgcttcgt tataaaaaaa cgggaaaaaa cgtttttcaa acgtcttcct
     6061 ctactcgtgc aacatatgta aaagaaaaac aagactcaaa taaagaaagt gcaaagaaag
     6121 agtaatggtt tccattgctc tttcttattt taaagctaga agaagtagct gatgtggaga
     6181 aaattgaatt ggctggctat attattggga taaatttttg aatttttaag aatttagata
     6241 gtggttagat acgattgatt ctttgtgtat tttgtattat ttaagtattg tgtggtattt
     6301 acattaagtt aatattgatg ttgttagtgt taatgaaggt tttcttttat ccaatacatt
     6361 agtcactcta tgatgcgagg agatgagaat aagtgtttca atataaaggt attcgtattc
     6421 gaaatcgaca taaatatgct tcagaacgat ttatttttta tcttatgttg ccggttctgt
     6481 tgctaatgag tggatttttt tctctctttt atacaacgat cacatgggaa tggtgctgta
     6541 tttattggat aatcgcattt ggtttagctg gtctatttgc gtatatgtgt ttgtattttt
     6601 acttttataa tgtttatcag cgattggttc ataaaggaaa attagcaaag atgatacata
     6661 gtcgtcgatt gattcttgaa agagtattga aaaatggacg gcggaaagtg gtgtattatc
     6721 caaaaatttt ttatcactat aaaaatggct taattcatgt tcgattgcca ttagatttag
     6781 gtccctttca agatcggttt aatgagatgg ctgggcaact agaagaagcc tttttttgtg
     6841 atttagtaga agagcaacga gagaaaaact atatttgtta taccttttta tacgatgtgg
     6901 aaaaaaatcg tattgggatt cgagatataa ccgtaaaaga tggcataatc accttaatga
     6961 agaatgttca atgggcattt aataaagcac cacatgccat aattatagga agtactggcg
     7021 gtgggaaaac gtattttata atgtctttga tctatgcatt attaccgtat ggtacgtttg
     7081 atatttgtga tccaaaacgt gcagatttgg ctagtttaga aaaaatacca atttttaaag
     7141 atcaagtttt ttatggtggt ggtattttat cttgtttaat aaatctagct aaagaaactg
     7201 ctaatcgata cgatttttta agagaacagc ccgagtatga attagggtac gattatactt
     7261 attatcatct aactcctcat tttttggtga ttgatgaatg ggcagcatat tatgcatcgt
     7321 tagatactaa agaaaaaaag aaggcaatgg gatgtttgaa ccaaattgct ttaatgggtc
     7381 gtcaatgtgg cgtgttttta attttaggta cccaacgtcc agatacaaag tatttggacg
     7441 gcgcgatacg agataatttt ggtttacgtg taacactggg aagagtatcc aaagctgggt
     7501 ataagatgat ctttgaacat acagtaaaat cattatttaa taagccgatt aaaggtcgtg
     7561 gttatattga ttcgggaacc gatcaagtac gagaatttta tgcgccattt atcgatataa
     7621 caagatttaa cttttttgcg gaatttaaac aactatctga tcaattaatg gctgaaaaaa
     7681 tcaaggagac gaaagaggga aaaaatgtat gaagaaatcc cagctacatg tggaactcga
     7741 ttaggaataa aagatttaat gattgactct tttttggcaa ttgttttcag tgagaagaga
     7801 ttaagcttct ttatcaataa aaaagtagag aatcgttgga gagtagaacg tatgtatcca
     7861 acgagttaac tgattggtta cagttgcctt atgacaatta tcgaaggcga atatgacggg
     7921 tttttacttc aaataaaagt gctcgatcct atagtgacca aattgtcgaa aaagcagcgg
     7981 aacagcctgt tttttatgga cgattcaaag gactttcctg ttcttatgtt aaaagtaaag
     8041 accggtctcg actgtaccta caagtagagg atattaactt gtcctttgcg ttgccagaaa
     8101 attaaatttg tcctcattag aatacggaag atgctgtgcg tatgctccac aagcaaacaa
     8161 gcctcagggc ggaaggacgc ggaagcgtcc tagcgttagc gaaagccctg aggtgcaggg
     8221 tgcgttgtgg ggcgtgcgcg tagcgcacgc ctaaaacccc catattctaa caggggggta
     8281 gaatttatat tcggtggcaa agatgggtga ttgaaacatt gatataacac tattttgctt
     8341 caaaaatttt gtgatatttt tcttcgcttt gtaacataaa atatcacaaa agaaaggaaa
     8401 gatatatttg gatgggacac aattaaagca aatgcggtta agtcggaatt tgacacagaa
     8461 attagtggca gatacattag gatggccaca atctttttta tcaatgatag aaaatgacca
     8521 acgaagttgc tcgaaagaac aagaagaagc actttgtgaa ttttatgcga atttttcaag
     8581 ttttacgagt ttagaaatta aatttgatta tgtccgtgta cgagttccga caaatgatac
     8641 gaaaacagtt gtggaagaaa ttttgggaat ggattttaac tctttttttt atgcagaaac
     8701 ccgcttatat ggttatattg aaatgtatca aaaaggcatg atccgtgtat taaattctaa
     8761 aaaaggtgac gataaaggag tgttgatcga attatctggt caaggctgtc ggaattatga
     8821 aagtgtactg gatgaacgaa atgatagttg gtatcaattc tttacacgat gtgtctcttt
     8881 caatggtgtg tctcgaagaa ttgatattgc ggtagatgat tttgaagaac tattttcttt
     8941 acatgaattt gcacaaaaac taaatcgtgg cgaatttgat tcaaaatttc gaacctggcg
     9001 atttcaagaa gaaaaacagt tgttagataa tctaagtagt ggcttatctg tttatttagg
     9061 tagttcacaa agtttgatgt atttttgttt ttatcagaag aattatgaaa ttgcaaaaaa
     9121 gcagaaactt ccgttggaag aggtcgaggt aaaaaatcgt tatgaaattc gcttacgtga
     9181 tgcaaaagcg gtcagtttta ttgaacaata cttaaataaa gtagattttt cagatttaac
     9241 gatggggatt ttagccaatc agttaataat gtttgaggga gagaaaaaca caaatgtgtg
     9301 gaaaccatgg ggaaaattga ttcagaacgt tggaaaagtc aatttgacag tgacaccaga
     9361 aaagccaaat tataatcgga aattgatgta tttaaagaca caacctgctc gtacaatgaa
     9421 gattgtaaaa actgtggatg aaattttagg attgaatcga tttggagaaa ttttagaaga
     9481 aacagaatta cgggaacaag atgaaaaaat tgtagaagat gaggtgcgtg ctgtttatga
     9541 atatatacaa gaaaatccag acgcgattca ttatttgcta taaagcttgc gataagatgg
     9601 gtgaaacatg attaaaacag aagaccaatg atggggagag tatatgattg cttgttaacg
     9661 attaataaaa gaaacgatcc tatgtgttgg aaatgatcta cagttattta aagaatattt
     9721 agattatcaa caatcaatca aaatgttaca tgtagaaata ggggaagtat taagctaccg
     9781 tattagtgat tcgttaaaat attcgttgac aaagatttat ttatatgcaa cacaagtatg
     9841 tggatatacg aaaaagcagt aaaaacaatg atgaaatatg acgatttgcc aagtaagata
     9901 tcctagattt acaacaagta ttggaagaaa aactatatct atatatgaaa aatagagggg
     9961 aaaagaaatg attcgatttt tattttctgt aggttggcat tttttgaaat tactgtttct
    10021 tttagtttgt attgtctgta gtattatttg gttattaaca ctttaaagaa aggaatatgt
    10081 tggaaaaatg ggacagtatt ttcttaccgg tgtttggtat gtattgaaat tagtgattat
    10141 tttaggtatt gcctatattt gttttagaat tttattatcg ggagaaggaa tgccaacgcc
    10201 aaaagatttt atcataagcg tgttgaattt tgtggcggat caaatacaag tgataattca
    10261 ttgggcgcag caacgttttg gataaaaaaa tatatttaaa aaatttaatg tttagaagtg
    10321 ggctatgtga tagaaaattt cgagtataag ttatctagat tgccaaagaa aaagggagct
    10381 acacaaaaag agctggctaa taaattaggt gtcaatgtac aaagcgcttc taatgttgag
    10441 gaagataaga gctaactaca tttagtaatt tagaaaaaat agtttctttc tttgatgctt
    10501 catcgattga attatttggt acgaataggg atcgaataat tgcagatgtt ccattaatat
    10561 tagaagatat ggataattta tttaaaaaaa tttgaatgat ctttatgact aaaaaagtaa
    10621 tcaaacaatt aaaaaaagaa gtttctgttt ttgatggaaa aaacctatca aaaagaacca
    10681 gttattgatc tttttgatag gctttatttc gttgatggaa tccatttatt agctgtttca
    10741 acaatcgttg ttgtaaaaaa gaattgtttt ggatgcgtaa ttctggatag ccttcaatgg
    10801 cttgattttg cttttcaaat gctagttttg catgatatgc ttcacgatct aaaataaata
    10861 gataatctgt ttgaaatgct tcaaatgtac agattttttg aatttttaac agatgaagat
    10921 aggtattgac aaagtgttct acacacataa ggttttttgt gtgtgaggca aaaagatgtt
    10981 ctttagctaa aaagttagta gtaagtgtat cagataaata aaagtaatct ggtgcgcgat
    11041 catacatttc gacaaaatag tcataaagta aagcaatttt ttgcttttct gctagaagat
    11101 actctatttc tttggaataa aattcatcaa tttgatgagt gtgtttaata acttgaacaa
    11161 ataatttcat atagtgttga atgaattctg ttcgttcgat tggttcacca aagggttgaa
    11221 gtatggacat cattctttct cctttcactc aagggaaaaa atcccttgag aatgaataca
    11281 tgtatttagt aaaaaaatat tttgactgct tcgatggtgc tttttccagt ttgttttgcg
    11341 ataagtttag gtaaaatctg ttgtaaccat tgttggtcag atacctgatc gaagaagtag
    11401 ccgattgttg ttaaaatgag tgtatctgtt gtatgttcaa ctaaacgtac agattcaaaa
    11461 ggacttaacc cagcaacata gttcaaaata ttttcatctg tttgttcaaa agatcctaaa
    11521 tagttattgg tattccgatc gtaagaatca acgataggaa tagcatttgt tcttagcatt
    11581 gcaatctctc cttgattaga aatactcagt tatcattttt taccgataga tttagaagca
    11641 agaactctta atttatgcgt tgttggtaaa ttgtcagacc gttcttcacc taagatttca
    11701 tatagagtta ttggtttcat tgttcttgct ccttttattt ttgtaacgtt gactaagagg
    11761 gaaataccct cttagtaata actgctttca taaaccggtt gattatcata gcggtaaaat
    11821 gtatcccaac tgcgattacc gtataattca ttgggatata aggctggatt aattcgtttt
    11881 ctaacaatgc tgtctttggt tcgtgcaagc ggataatcga taaattcatt tggtattggc
    11941 atagtttctc cactcataga agtatagttt tttacagttt gctttttgat gggtcgaaac
    12001 catgctgttt ttttggttaa tttaataatt tgccaaaaag taacgttggt ttgttcatag
    12061 ccccaactac tataaaaaat gtctcctact ttgtatggtg tatttgcttt catgatctat
    12121 tcctccaata atatttgatt tgccttattt gatacttagc cgaatcaacc aaccattttc
    12181 ggcagcaagt tgtctccgag gcgggtgacc ttttgggaga tttcaatttc tttttgtttc
    12241 cattcacctc acttttttgt tttggttggt cattttcgta tagctaagcg ttcgtcggcg
    12301 tgcttttagg tcacaacgtg tggtaagaga aaacaaggga atgctgtagg aaaaagtttt
    12361 ttatgaaatg atcaaaaaag tttttccgcc ccttgttttg tcctaccatt cgttgtaaaa
    12421 gcactactgc cgatgatcgc ttagattggg tatacgaaag cgaccaacga aaaaagtatg
    12481 ggaataaaaa gaaatcgcac tgaaatctcc caaaaggtca agatggtttt aataagaaat
    12541 tccttttaat acatttgtta ttttgataat gtggtggtat aaaatagatc aaatagttaa
    12601 aagaggtgtt tgtatgaaga aaaaaggcat tccttattct ccgaaaccta gaaatgcttt
    12661 tgaaaggggg ttatttaaat attttgaagg cgaaagagat caggaagaaa aagagaagaa
    12721 tcaaaaaaag aagtctagtc aagaaaaaga aaatatagaa aaatagtagg tgaaaaaata
    12781 gagaagtatg aaaaaaagtt taatagtatt gattgttgga ttaagtatat ttggaagtgt
    12841 tttatttatt ggaaactcgt tgttttctaa caaagatgtt acggaacaat cccctgctag
    12901 cacaacggaa gaggtatctc cagagctatt attagagacg gatgttcttg atacaaagaa
    12961 acctgagaca attccttcgg aaaacgagct ctatcaagga gatctttcat ttgaatatgc
    13021 ggatccggaa aagccgtatg tactaacgat tcggtttata gataaagcga atcatgaata
    13081 tgtagggcct gataaaaagc cattgaaaag agagaaagaa ttgattctag gaaaagctaa
    13141 aggtgtcgta cacgtagttg taaaagccaa tagatcgatg ttaacccata ttcagaagtt
    13201 aaaagatatc caagtgtcca tgacattaaa tgagagaaat gagaaaacgg aatgacggaa
    13261 atcagacatg ttttgggaat atctgttcta cttttatcgg tttatttatt ttgttccatc
    13321 tttatagttg cttgatcata ttacaaaaat gaaaggtcat ttttttcttc cctgttattt
    13381 atcatcatta aaaatgatga tattatttct ttaaacacct atttaaattt gtttctacaa
    13441 ttttcagtat gataatgatc gttattttaa ttaggtgtaa atgaagaaag gaagaaaaat
    13501 atgttgaaaa aagtgttacg atttggggta tgtataagta tatggttggt aacatcttcc
    13561 acttttgtgc caagtatgat tgcagtggcc gattcggtgg cgatacaaga aacgatcgca
    13621 tctgatagcg agggggaaga gaagcttaca gaacgctcgg acgatgcgtc agatggacaa
    13681 actgaaaagg ttgaagtaca gaaaacagaa actactcaaa cgacggtatc gagcagttca
    13741 gatgaatcaa gtgatcttac ccagtccagc gaagaaactg cgccagaaga agtcgatgag
    13801 tctaccgaag agtcttcgga tcctcaggaa caaacgattt ctcatgaaga agaaacgaag
    13861 gaagcagttg attcatcaac gattgatttt gaaggaacac gatcttctga atcattcggt
    13921 aaacatacct ctccaagtat tgataaacct aacgaaaaaa tagccgaacc agtctcttca
    13981 aatgaaggag cagttgtttc acggcgaagc cgccgagatc tttctgcggt ttcttcaaat
    14041 cacccagaag aggaaccggt ggtcgctttt gatgaaaaag cctttgatgc cgcaatcgat
    14101 caatacattg atcatgcaac agaagaagaa ttagggttag tcataaattc aagcaatgaa
    14161 aaagaattgg ccgatgcttt agaatatctc ttgttgaatc aattggatga gtcctttggt
    14221 gtagaagaac tcgatgaact aaagaagttc ctcacggcag atgagattga acgattggaa
    14281 aatgaatcgt cgttagagac atttgaacaa ctgcttacgc aatactataa tgatcgagaa
    14341 cagaaattgg aagaaggagc agcatttagt gacttctttc tagcaagtac cgatgaggaa
    14401 atcgatcgga tgttagaggt aaaagatgaa caagcattgg aacaagtgat ttctgaaatc
    14461 agtgcttctc ggaatagtca aacaagtgga aagcgaaaca agcgcttctt agtcattcca
    14521 ttgcttgtca aaggagcgat gttggtaatc ggggcagggg tagctgctta ttcaagccat
    14581 cagttctata agacgatgga agcacaacgt gcggaaaaga aacgaatggt cgaacgctgg
    14641 cgttaccatg aacaacaagc acaaaagcgg catcaagccg cacaacaagc ccgcgccaaa
    14701 gccgttgccc gtgccaaatt acaagcagca gcccgtgcaa aagcgcaagc cacacaacga
    14761 gctcgtgccc aagccgcagc aaaagcgaga aaacaagcac aaaattgggc taaacaacaa
    14821 gccgccgctc gagctcgtgc acaggcggcc gcaagtgcac gaagaaagtc aaatgcgtcc
    14881 tatgttcctc cggtaactcg tccgaaacca gtaatcaaag cccaacccaa agtacctgca
    14941 aaaccagtag ccaaaccagt aacgaaacca acttctccag cgaaaccgaa gccaacgacg
    15001 acccccaaaa atacgatgca tcaagtacgt gcaggagaat ctgtttggtc tatttcgcat
    15061 aagtatggca tcagtatgaa tgacttcatc aaatggaaca aaatcaaaaa taatctgatc
    15121 catcctggcc agcaagtcat cgtcaaacaa ccagcaagta catcaaagcc agtgtccaaa
    15181 cctgcgacaa aatcaagtac gccagccact tacaaagtaa aagcagggga ttcggtttgg
    15241 gggatctgtg agaagtatgg gttatccgtt tcaaaatttg tccaatggaa taagatcaaa
    15301 aataatacca ttcatccagg acaagtgatg catttacaag aaccgaaacc ggcatcaaaa
    15361 ccagcaccaa aaacttctcc tacgactaat acgacgtata cggtaaaagc aggagattcg
    15421 gtctggttga tcgctaatat gcatgggatc agtatgaatg atctggtgaa gtggaataag
    15481 atcaagaata atacgatcca tccgggccaa aagttgacag tcaaacagcc tgtttcatca
    15541 gggaaaacaa cgacaaaagt acccgcctct acaaatccag tcacccacaa agtctcttat
    15601 ggtgaacctt tatggctgat tagtagtaaa tatggtgtga ccgtcgatga attacgcaaa
    15661 cagaatggca tcaaaggtga tttgattcac cccggccaag tattagtcgt caaaaaaggt
    15721 atgaccacga gtcattcaac tcctgcagga aaaagcggaa ccagctatac cgtaaaagca
    15781 ggggattctg tttggttgat cgccaatcga tacgacgtga gcatggatga tctagtgaaa
    15841 tggaacaaga tcaaaaatta tacgatccat ccgggtcaag tcttaacgat ccaaacaatt
    15901 gtttctacac cagcaaaacc tgcgattacg acaacaccaa aagtagaatc caaaccagcg
    15961 attaccacga caccaaaagt ggaatccaaa cctggagtga ctaccacacc aaaagtggac
    16021 gagaaaccag taattacaac attaccgaaa gtaaaagaac aacctgtggt cacaaccgtt
    16081 cctaagactg aatcagaagt attagttgag aaagccagtg ggtctacagg tacagtctgg
    16141 gatgatatta aaggtacaca acctccaaga gaaggaacta ctattcctaa atcgtttgaa
    16201 ataattgtta atggggaaaa gttgtgggta aatccaaatg gaaccaagca catggtagaa
    16261 tattcaactc gaaatctatc tcatggacaa aaacttaccg aacaacaatt gttaaggagt
    16321 tttcaaggtg ctgtagaaca agctacttct acagggataa aatttgaaac taaaataata
    16381 atagataatt gggaattaat atttagtcca gctagagaag caggacaatt accagttatt
    16441 aaacatgctg tatatctacc ataactatga aaggagcaaa ttatgaaaat taaaagttat
    16501 gaggataaat tagtcaaaga tgatatagaa gttgactatt atgtcccaat cacagtatca
    16561 tttccagaaa atgatgataa gtataaccta ggagaatttt attattatag attcgttaat
    16621 gaatatgaat catttgttga gattaaaatc aattctgtta cacagaaaat tgtagaagta
    16681 gtattcacat ccatcaatga tattgaagat tccaatttat ttattggaga gtatgcagaa
    16741 aaaaatccag tgatccaaac agatattttt gatgaaaatt cgattataac taaagaatct
    16801 gggtttaaaa tatctagaga acacaaaaaa ttatgtttta aattagataa agaaaagatg
    16861 gattctgttg taaagatgtc taatcatgta tctttatttc taaatgaaga cagtgagatt
    16921 attggtttag agttttctag cttttcagat aatgaatggg cagaactcaa tgaaagtata
    16981 aaatctacca cttgatttaa ttttaaatga gaagaagata ggattttcaa cagctatttt
    17041 gctagattct gaggatgaaa caaaagaatt ttgaaagaac aaattcaaat gctaaaataa
    17101 acggtgggca tgttatgctg aaaaggttcg agggataatc caaggtacta ggtattttgt
    17161 gagttcctcg ggcactatca aaagcacatg cccaataaag aaagtcaata gcaatattag
    17221 gagagactaa tgatctattg actttcttta tagtgtttta cggatcagaa gaatcatttt
    17281 tctcattgcc ttccgctcct tttagaaatt gttttataac aagtaccttc acaacttcta
    17341 tttagtcatt tgtcatatta attttctctt ttccagattc aaaaatagtg ttcatattta
    17401 ctattagtga cctttgcttc ttcagttgaa aattttatat ccactttaga ggcatgtaaa
    17461 aggttaattt gagaatttcc agaagataat ctactataaa accaacgtcc aaaccagtgg
    17521 caaaaccaag tacgccagct acgtacaaag taaaagcagg agactcagtt tgggggattt
    17581 gtgagaagta tgggttatcc atttcaaaat ttgtccaatg gaataagatc aagaataata
    17641 cgatccatcc tggccaaaag ttgacagtca aacagcctgt ttcatcaggg aaaccaacga
    17701 caaaagtacc cgcttctaca aatccagtca cccacaaagt ctcttatggt gaatctttat
    17761 ggctgattag tagtaaatat ggtgtgaccg tcgatgaatt acgcaaacag aatggcatca
    17821 aaggtgattt gattcacccc ggccaagtat tagtcgtcaa aaaaggtatg accacgagtc
    17881 attcaactcc tgtaggaaaa agcggaacca gctataccgt aaaagcaggg gattctgttt
    17941 ggttgatcgc taatcgatac ggcgtgagca tggatgatct agtgaaatgg aacaagatca
    18001 aaaattatac gatccatccg ggtcaagtct taacgattca aacaattgtt tctacaccag
    18061 caaaacctgc gatcacgaca acaccaaaag taaaagcaaa accggcgatt accacgacac
    18121 caaaagcgga atcaaaatct ggagtgacta ccacaccaaa agtggacgag aaaccagtaa
    18181 ttacaacaat accgaaagta aaagaacaac ctgtggtcac aaccgttcct aagactgaat
    18241 cagaagtatt ggttgagaaa gccagtgggg atggaagtag attggatatt aatattaaaa
    18301 attttgaaat caagaataaa catttgaata gttcaactgc taaacgggct agaaagttta
    18361 atgtttcttc agccgaagaa gctaataaaa tagttcaaga cgcattaaaa aatggaaaac
    18421 ttgtagaagc tataccaaat ggagtaggga gccaaggaca aaattctttt tctagtatta
    18481 ttgatacagg gaaagttatt ggaaccaaag gggaaacaca tataaaaata gtttatgatg
    18541 aattaaaaaa tgtgtggact acctatcctg tcccaaaacc ttaaatagga ggtaagcaaa
    18601 gtgattgata aacaaataac gaatattttg caatcgtata aaaaacaaca aatatttaaa
    18661 atagaggact ttttactttc agaaattgat gaagataatt tacaagaaac aatagatttt
    18721 gtagtttctg atgatgttag taagaaaatt aactttagtg atgaattata tgatgggaac
    18781 gagtacgaag gtgtattttt agaaggtaat caatatttac tatctagctc agaaggaaaa
    18841 gtaatgataa ttgatatgtt aagtgaggct catggtgtta atataaaaga tactcgagtt
    18901 caatttgatg aagaaaaatt tatcaaacta atcacgaaca aaaaagaaat tcttaattgg
    18961 attaaaaatt ataaagtgga taaataaaat aaaaaaggca ctttactatt cgattggcgt
    19021 cgaatagcaa agccttgaat agtaagcata cactcactaa tcaagttgct aataaaaagt
    19081 tatctatgta tagaatagta taagctgaag ttgaaaaaga aacgatttag ttgtatcgtt
    19141 tctttttcta ttttatcgct taattttaat agttaattat ttgaatgata tataaatttt
    19201 aatcaaagaa agacaattta ttgttgaaat agttgttgaa gctttcgagg cgttcttgag
    19261 gtacagttga aagctttata tccactttag aggtatacaa aagtttaata tgagaattct
    19321 cagaagataa tctactataa aacagtagat aagtcagcgc ccaaaactaa ccattcgttg
    19381 taaaagcacc gtcgtcgatg atcgcttaga ttggctatac gaaagtgagc aacaaaaaaa
    19441 gtttgggaat aaaaagaaag cgtactgtaa tcttccaaaa ggttaagatg attttgataa
    19501 aaaaatttaa tatatttgtt atttttataa tgtgatgata taaaatggat cgaacagttg
    19561 aatgaggtgt ttatatgaaa aaaagtcact ccttatcgtc caaaacctaa aaacgttttt
    19621 gaaagaggaa gcataaatat tttgaaggag aaaaggggca agagttaaaa gagaagaatc
    19681 aaaaaagaag tccaagaaag aaaaaatgtg agtatatttt ttagaaagaa aggaattgtt
    19741 gcgaaactag accgtaaaga tttataagta atcagtaacc catacttttt atatttaaag
    19801 aggttatttt tctgtaaatc gttgtaaaaa atatctgagt tgtagtattt t
//
LOCUS       DAXLPQ010000048        19694 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.048, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000048 DAXLPQ010000000
VERSION     DAXLPQ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.048"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(65..265)
                     /locus_tag="ACF3UO_002063"
     CDS             complement(65..265)
                     /locus_tag="ACF3UO_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3658035.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(717..1037)
                     /locus_tag="ACF3UO_002064"
     CDS             complement(717..1037)
                     /locus_tag="ACF3UO_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658036.1"
                     /translation="MKKRVLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1540..2658)
                     /locus_tag="ACF3UO_002065"
     CDS             complement(1540..2658)
                     /locus_tag="ACF3UO_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658037.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPEIEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            2891..3013
                     /locus_tag="ACF3UO_002066"
     CDS             2891..3013
                     /locus_tag="ACF3UO_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658038.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            3129..4436
                     /locus_tag="ACF3UO_002067"
     CDS             3129..4436
                     /locus_tag="ACF3UO_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFD3658039.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGESRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANMFVIGWRRVAEFFGNLF"
     gene            4555..5754
                     /locus_tag="ACF3UO_002068"
     CDS             4555..5754
                     /locus_tag="ACF3UO_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFD3658040.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(5781..7049)
                     /locus_tag="ACF3UO_002069"
     CDS             complement(5781..7049)
                     /locus_tag="ACF3UO_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFD3658041.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(7104..7170)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(7212..7859)
                     /locus_tag="ACF3UO_002070"
     CDS             complement(7212..7859)
                     /locus_tag="ACF3UO_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFD3658042.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(8267..8770)
                     /locus_tag="ACF3UO_002071"
     CDS             complement(8267..8770)
                     /locus_tag="ACF3UO_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3658043.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(8893..9657)
                     /locus_tag="ACF3UO_002072"
     CDS             complement(8893..9657)
                     /locus_tag="ACF3UO_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFD3658044.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMALTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFMVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKENAESLNVGVAAGIVLYHFSL"
     gene            9765..10040
                     /locus_tag="ACF3UO_002073"
     CDS             9765..10040
                     /locus_tag="ACF3UO_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFD3658045.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEEDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            10717..11667
                     /gene="yidC"
                     /locus_tag="ACF3UO_002074"
     CDS             10717..11667
                     /gene="yidC"
                     /locus_tag="ACF3UO_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFD3658046.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(11846..12820)
                     /gene="lacD"
                     /locus_tag="ACF3UO_002075"
     CDS             complement(11846..12820)
                     /gene="lacD"
                     /locus_tag="ACF3UO_002075"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD3658047.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(12817..13275)
                     /locus_tag="ACF3UO_002076"
     CDS             complement(12817..13275)
                     /locus_tag="ACF3UO_002076"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFD3658048.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKDVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTKIATILTKEIGEDL"
     gene            complement(13272..14738)
                     /locus_tag="ACF3UO_002077"
     CDS             complement(13272..14738)
                     /locus_tag="ACF3UO_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3658049.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDASMGMMVPVLAAYIAEGIAKRPGLIVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDDSKAANRTVIEKGRAGDLS"
     gene            complement(14720..15670)
                     /gene="pfkB"
                     /locus_tag="ACF3UO_002078"
     CDS             complement(14720..15670)
                     /gene="pfkB"
                     /locus_tag="ACF3UO_002078"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFD3658050.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIREERFERWENIN"
     gene            15813..16562
                     /locus_tag="ACF3UO_002079"
     CDS             15813..16562
                     /locus_tag="ACF3UO_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3658051.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINVLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISQKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            16828..18306
                     /locus_tag="ACF3UO_002080"
     CDS             16828..18306
                     /locus_tag="ACF3UO_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFD3658052.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(18374..19465)
                     /locus_tag="ACF3UO_002081"
     CDS             complement(18374..19465)
                     /locus_tag="ACF3UO_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFD3658053.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         6082 a         4031 c         3410 g         6171 t
ORIGIN      
        1 agaaaataga caaaaacgcc cagacacgca aatgtctggg cgtttatttt ttagtatagg
       61 ttaattaagc tttagtaacg tttgttgctt gaggtccgcg ttggccttct tcaacatcga
      121 aagttactgc ttggccttct tctaaagttt tgaatccgtc gccttggata gctgagaaat
      181 gaacgaatac atcgtttccg ttttctgcag tgatgaatcc aaatcctttt tctgagttaa
      241 accattttac tgtacctgtt tccataataa aaatcctcct tgtgtatcaa cacatatttt
      301 gcaattactt gaatggtgta tatctggaag atgtttattt gaaacaagct accacagatt
      361 accgaacaaa aactactcct atagtatatc ataccgttta caaaaaagct agagtttttc
      421 gacttttttt attaaaaaaa gttttctcag cgattacata aagtgaaaaa ccgaactttt
      481 tttaaaataa acgaaatatt gttcagttgg tgtttttttg ctctgatgtt cttctttaaa
      541 ctaaaaaaat tattctttct gactacttat cggttctgtt tcaacggtcg aggctgggga
      601 agattcttta gtaggtctga tgttctcatg gtatttctga tagcctatga cagtgaccag
      661 aagaacaagg caaaccaata cgatcaacga gattagtttt tcttttttgc tcatatctat
      721 acctcataaa taacaggatg atgtccatca tatttctgag tatgagtaaa agcaaaagct
      781 gcagctgtag aatgtaagaa atgccagcaa ctttcataat cacaggtcgg acagtaccaa
      841 aagtaaccaa atcttggctg caaagaccgt tcttctgttt caggaatcgc agaatcaaga
      901 tctgttgtct gtacataaac atttttgtac agacgtgtgc ctgtaatagg agaccgctgt
      961 gtttcttcag caaaaactgg ctgacttgtt aaacttaggg atagaaacag caaacaccat
     1021 aacactcttt ttttcataaa gacctcctta tcgataagtt tttcccaatt aaaatcatat
     1081 ctcaagaacg cccgttattc acattttgtt cataaatgat gttttttgta tcataatcgt
     1141 caaaaagagg tcgtgaccac gtcacaacct cttttttaaa tggtgttcca gaagtagctt
     1201 cttcggaaat aagccgaaat ttcacaaaaa tttgagaaat aatttttgtc aatctcttct
     1261 tatttcttga agctgaccac ttctgtcaca acctcttcct taaacggtgt tcaaaagctt
     1321 gcatctgcgg taataagccc accaaacaaa aaatatgaag agctattttt gcttgctgtt
     1381 cttattactt gatgcagaac agctttttca caacctctca tacacggtgt ttaatcagct
     1441 gaccttcggt attagctcaa aaaacggcaa aatatgtgaa actatttttc cgtttgtttc
     1501 tctaatactc aggtcaaaac actgttttca caacctcttt taataacgaa gaatcgctgt
     1561 cagactcttt tcatctggcg catctttttg atccaaaata aacactttcc cgccattaat
     1621 gatcacatca tctgctaatg cattcaacac ttgacgccga tcatattcta tttcaggatc
     1681 ttcaccgaaa ccatcagcta agtttgacgt agcgataaat agatgcgaca cttttccttc
     1741 tttcgcagct ggaacgatat caactaactg atcgatgaat ttcttatcta agagtttatt
     1801 gtattctttt gattcttgag ctgcgagttc acttgacagc ttcttcgccc cttcttcgat
     1861 atctctaaag gatagctgcg caggagaagc agaaatcgca acgtctgcac aataataggg
     1921 atttttagca atttttttga acatcgtctg attttctggt aatgcaaata aataaatcgg
     1981 ccattgttct ggattttcga aagaatcctt caagtacgta tcaacagctt ggtaatagtt
     2041 gacccaatcg atctctactt cttcatcttt tggatttacg ccatggaaag ttactccatc
     2101 tcgggctccg cctcctccat tagaagagaa gttcaaaccg ccacctgtca gttcagatcc
     2161 caatgcagta acgacatcaa ccggtgcccc ttctggtaga gatacttctt ttacttgttt
     2221 gttgctgact tcatacaatt tcatggagtc gcggttcaat cccaacagat aataggaata
     2281 gttgaactgt ccatttttga taatggccag taaataagga agatcactta catagtattg
     2341 atcgtctacc gggatactca aacgatggat ataggtttgg tcagcagtta taatgaccgc
     2401 tacactcgta gttgcactac gccaaaacga aggatctcct aacaaatttt caattttttc
     2461 ttggaacggg gaccagtcat gttcggaata ttttttctca aaacgtttct ttgcttcttt
     2521 cgcaaaattt ttgaatttga tttgatcttt ttccacatct tgatgggcga catgcgtatt
     2581 cagcatgatc gtgacgaatg gtcctttagc gccttctgaa gtcaattgtg acaataattc
     2641 tttatccttt tttgccataa acgtacccct cctaaaaaaa tcattccttt gtttctatct
     2701 aaagtctacc acaacactat ttttccatac aataaaacgt atctaaaaaa ataaaacggt
     2761 ttctacggtt ttaaatttag ctattttttt aagttatctt cataatttcc tcaattattt
     2821 agccccagtc ttcaactatt cttcatgaaa tgctgataaa ctaaaaaaaa gaataaaaga
     2881 ggtggatctt atgcatttga ttatgatttt cagtttatta agtattatca gtttatttgc
     2941 tttcagcgct tcccgcttat tagatgcgga aacacagcct attcctgtaa aagtacgtaa
     3001 aaacgaccgc taaccttcca taacgtgcgt tcttatccta aagttttttc agaaacattg
     3061 aaactctctc ccctctctga taaaatttta atttgtagcg aaacaaatta attacaagga
     3121 gatcggatat gtccataaaa aaaacacgtc tagtcctatt attggctagt ctcattcttt
     3181 gccttgcttc ttttctacca gctgttgctg tgcaagctga agatacgttc aaagtaaatg
     3241 caaaagcagc ttttgctgta gatgcgcaaa gcggtaagat tctttatgat caagatggag
     3301 aaaaaaccat ggggatcgct tcaatcacaa aaatcatcgg tctttacatc gttcttgatc
     3361 aagtaaaaga aggaaaacta tcatgggatg ataaagtttc gatttcagat tatgcagaaa
     3421 atttgagtat caccccagat ttatcgaatg ttcctttgca taaagaaaac acctacactg
     3481 tcaaagaatt attcgactct gcaatcatcc agtcagccaa tgcttcaatg gtggccttgg
     3541 cagaaaaaat ctctggcagc gaagctaaat tcactgaacg aatgaaagaa caattgaaag
     3601 attggggaat caaagatgca acgatcgtta atgcatcagg actgaataac tcttatcttg
     3661 gcgaaagccg accagaaggt actggagaaa acgacgaaaa tcaaatgtct gctcaagatg
     3721 tggccatcgt ggcccgtcat ttgatcttgg attttccaga aatactggac gtatctagca
     3781 ctacgacaca aatgtttggc gaaaacacgc aatcaccagt ggaaatggtc aactggaact
     3841 ggatgctccc aggattcgtt aattacaagg aaggcgtgga cggattaaaa actggtacga
     3901 ctgagcttgc aggtgcttgt ttcgttggta cgatcactaa aaacgatcaa cggatcatca
     3961 ctgtcgtatt gaatgcggac ggccatgcgg aaaacccgag tgcccgcttc aatgaaacag
     4021 accgtttgat ggactactgc tatgacaatt ggtcagaaaa agagctcgga aaagctaacg
     4081 caagtattcc tagcctaaaa accattgatg taaaagacgg aaaagaatca acagttcctg
     4141 ttgtgcttaa aagccctgta aaagtatggg tacgaaacga tatggatact ggcaaattaa
     4201 cgatcacgcc aacacttgac aagaagcaag tcactgacaa cgagatccaa gcacctatgg
     4261 ataaaggtac aaaaatcggt accgctacga tcaccttggc agacgataaa ttaggctatt
     4321 tagaagacaa caatgcgcca tcaacagaga tcattacgga taaaacagtg gaaaaagcga
     4381 atatgttcgt gattggctgg cgacgcgtcg cagaattttt cggcaacttg ttttaattga
     4441 acaataagaa aagcatcttt ccatcggaaa gatgtttttt tgctttttct agtttaaata
     4501 acagcttttt tcatctattt tcgttatact gtataagaaa aaggagttga atttatgaat
     4561 ctaaccagag atctgatctt tttagttctc tatcttattg gggtattctc tatcgtttat
     4621 tggcgaaaac agaagaagga tccttccttg ttcttttacg gcagtacgtg gacatttacg
     4681 gtaatcttaa cttattttgt cgtgttggaa attttttatt cgacctttta ttttttgatt
     4741 ccattgttgt tctttagtat ctttgctttt tcttatttca cagaaaaacg aaggctgctg
     4801 aatggtcttt tattcaatgt tttcctcatc agtttcggca tctacttgtt tgtcttgctg
     4861 tatgaaacgc aaaatatttt ccttggcgga ctgatcgcct tgatcacgat tccattgcta
     4921 cttgtccttt tatttggtat ttatggattg attgtttttc ttttttggaa cggggtcaca
     4981 gttttacgta gagaatcgca ttcattagcg aatcttttaa cgttgatact agccattttt
     5041 cttacactgt ttcttgtttt tgactttttc ttgttaaaat atttgccgca atggataaat
     5101 gctttgtttt tctgcgttcc cctgatcttg atctatctat ttatcgtatt ctacaacttt
     5161 ttgactgtct cattcttgta ccagttcaac cggcctcgat acaatcaaga cttcatcgtt
     5221 gtgttaggcg ctgggttgat caatggagaa acagtttctc ctcttctagc caagcgaatc
     5281 aataaggcaa ttgcttttta tcgggctcaa agccgtgcta cattaaatcc gcccatctta
     5341 ttgatgtctg gcgggcaagg agcagacgaa aaagtaccag aggccattgc gatgaaacaa
     5401 tatgccatgg aacaaggaat ccctgaaaga gacattcttg tcgaaaccaa ttcgacaacc
     5461 actttggaga acatgctcta ttcaaaggaa atcatggatc agcaaatgaa agggccatac
     5521 cgcgcgatct ttagttccaa caattaccac atttttagag ccggtcttta tgcgcggcaa
     5581 gccaaattga aagcaaatgg tattggtgca aaaacagctt tctactactt gcctaatgcg
     5641 tttttaagag aatacatcgc catcttgatg atgaacaaaa aaagacatat gatcatttgc
     5701 ggattgcttt tcgcaggctc cgcattctta tcgctgatta ctttactttt ctaaaaaaac
     5761 aaggtgtgac aaaacatatg tcacaccttg tttttttctt tcattctctt aactattggc
     5821 aaaaagagta tccctttttt gaccgctact tgctgagcag aataaatacc gctgttgcct
     5881 gaacacataa agctgatcaa gcagatcata aagaagtaaa cagccgcttg tgaaccgaac
     5941 aattcgatcc ccatcacaaa gcaggcaatc ggtgtatttg tcgcaccaga aaatactccg
     6001 ataaagccca atcctgcgag aaaaggaaca gaaacatgga gcaaaggcgc tagtgctgca
     6061 ccaagcgttg caccaatttc aaacaatggt gtcacttctc ccccttgata tcccgcgcct
     6121 aaagacaaaa ctgtgaagaa taacttccca ataaaatcat agacatgtgc ctgtccatta
     6181 aatgattctt gaagtaacgg aagactcaat ccgagataac gttgtgtttg caaaatcaat
     6241 gctgctgcca caactacagc cccacctatc gtatttcgcc aaacaggatg aggaatccat
     6301 tgtgcatacc gtgcttttaa aaagacgatc gaacggctga atacccagcc aatcaaacca
     6361 aaagcaatcc cagcaacaaa aactttgaag aacagcaaca tactccattc agggatcaca
     6421 cccatttggt aatgtaggtg agaaacacca tagctttccg tcatgaaatt tgcaaacagt
     6481 gcagcaaaga agctagggaa gatcgcttct gttcggactt tcccgattgc caacacttct
     6541 aatccaaata atgttccagc taaaggtgtg ccaaatacag aactaaaacc cgcactgatt
     6601 ccactgataa tcaagatttc ccgttctgct ttatccaatc ggaacaaacg tgctgtatta
     6661 tctgctaacg ctccccccat ttggactgct gttccttcac ggccaacaga tcccccaaat
     6721 aaatgggtag ttatggttcc aaacagtgta agtggaataa gccgcaacgg gattttttct
     6781 tctccaccat ttccttgatc gatcactaag ttgtttccac gactagaaag tccgccgtga
     6841 tacgcataga gataagcaaa aagcgcacca ctaactggta gtagataaag gagccaagga
     6901 tgtgatagtc ggatatctgt cacaactgtc aagctattta agaaaaaagc agacaagctc
     6961 cccatgaata taccgagaat cgctgtgatc accagccact tcagcatgta cactaaaatg
     7021 cgtactggac tcggtaattg tttttccata aaaaattcct cctcaataaa aaaacgccta
     7081 ctaaagaaag gggctatccc cagactttag taggcgtcat tagctatctt tcgttagcat
     7141 ttaaaggcga acaccatcac ctattcactt ccattaaaag atagcatatt tttctgtaaa
     7201 aaacaataaa attatcgttc tttctttaca cgttcagcaa attcatagaa aggagccaat
     7261 ttcgttaact gttgattaca ttggtcacta tcatgacaaa tataattccc ctttttcgta
     7321 tacgtgccat cagaacctgc tttcgttgta gaaagaaaaa gcgaaacatt cgatgttttc
     7381 tgacagattg cacagattcc cttatttatc gttggtgata aagtaccgct aatccctttt
     7441 aatttttcat cttcgtaata gaccatgaat tttttctgcg tacctggatc attccagccg
     7501 atgtacgtat gttcttgcaa gtcgatttca ttccaagctg gttgtttgag ttttttcact
     7561 tttcggaata atttctcgat ttgtggtttg ctaggctgca taaacggctg aacgatttgc
     7621 ttcagctcct ccaatgctct ttctgcttgc gcttttgtca gttttacgtc taaaactgtc
     7681 gttaaaaatg tatcgatttc tggcagttcg tgatctaata tgtctcgaat cttttcagct
     7741 gctagtgcct gaactgtttg caccgttttt ggatcattga cagatgagta cgcatttaat
     7801 aactgttcta cttctctttt tataaaaaaa tattggtatg gttttattgt ttgttccatg
     7861 attttaaagt cctttcttct aaccaaagtg catactttgt agaaaaaagt gatcttctgc
     7921 aaagtatgtg ttacctgaag atcccggact cttttaaata agatacgttt tgcatcttat
     7981 catcaccccc tttaatgctt attcttctat gtacatgatt cattcgataa ataaaagtaa
     8041 accgtatctt gaacagatag tcaactgcaa acagaaaaaa ggactgtgac aaaagtcgtg
     8101 tcaaagtccc ttgtttcgaa tgaatggtgt tcaaaagctt gcatctgcgg taataagccg
     8161 aaacttcaca aaaatttgag aagtaatttt cgtaaattcc ttcttatttc ttgaagctga
     8221 ccacttctgt cacaacctca atatggtcta ttattggttt tacctgttaa atcgaggatt
     8281 ctttcccaaa gtaacgttgc catctcttac gcatacttgc agacatgggc tgtgccgctt
     8341 ctttgactgc gcagtatttg tccacgaatg tcacgatata tccttcttta tacttaggcg
     8401 gtgcgatcgt tgcaccccac atgtgcttca aaatgatatc tcgctcaaga tccgacaaat
     8461 cggtgatttt ttctgcattc tttacagcaa ttcttggatg gatatacgca tgtgtcccct
     8521 cgtcaaattt cgtcgtacgc caatcatagt agaacagatc atgcaaaagt ccagcacgcg
     8581 ctgttgcttt agcattgcca ccccattttt ttgcgagcag ataactatag taagaaacac
     8641 tgatggaatg ctccaaacga gtggaatgaa catgctgtgt gtaattcgct aattttttca
     8701 ctgcttctgt ttctaaaaga tcttgtacat aagacatata ttcttcgtct tcacgccatt
     8761 tttctgtcat aattatcgat ctgccacctt tttgaatttc attttcttct gaaattgatc
     8821 taagtatacc accagtgttc ggattattct agtcgctcta gataaaatag ctaaagctta
     8881 atagttcctt aatcataaag aaaaatgata aagaacgatc cctgctgcga ctccgacatt
     8941 caatgattcc gcattttctt tcattgggat atatacgttc tgatcagtca aagacaagat
     9001 ttcctgactt actccctgac cttcgtttcc catgattata gcgaaatcct ctgttttttc
     9061 tactttgtct aatgcatgtg cttcttcatt taattctgta ccgtacacca taaacccttt
     9121 gcctttcatt acagggatca cttctgccaa atctttttgt aacacaggca aatgataatt
     9181 gcttccctgc atgcttcgca gcacctttgt actataaata tctgccgttc ctttacctaa
     9241 taaaacacca gccataccaa acgcatctgc cgtacggatc atcgttccca catttccagg
     9301 atcctgtaca ttatctagta aaagccagcc tcctgaaaaa tctggcgtat cttcagatgt
     9361 taacgccatc actgctaaga tcccttgcgg tgtaggtaga tctgacatag cggtcatgac
     9421 ctcatctgaa actagaaaag tagaaatctc tttgtttaca gccagccagt ctccccattc
     9481 tttcatacct ctctgtgtca caaaaagttc ttttatttct gcatcagacg acgcagcttc
     9541 ttcgatcaga tggaaccctt ccaaaagata ttctgccttt tcttctctgt atttcttttt
     9601 atgtagtttt tttaattctt tgattcttgg attttttgct gattggatct ctttcacatt
     9661 ccttcacctc acctgattat atcatggaat aggtgcttga gcttgtttca tcctaaaaaa
     9721 atcggtatca ttgatttata aaacaggaaa gaaaggtgac gaacatgcgc aaagttaaaa
     9781 tgaatgtcca aggacgtgtc cagggcgtgg gatttcgcta tatgaccaag atggttgctg
     9841 atcagttagg cgtgaccgga acggtaaaaa acgaagagga cggctcagtc acaatcgaag
     9901 caatcggaaa tgacgacatc atccaaaaat ttatcgaaga agtcaagaag tctccgagcc
     9961 caagtggacg agtgcagtat gtggatgtcc aagaagatcc gatgattgag gaacgaaaga
    10021 aatttgatgt ggtgggataa ggttgtgaaa aggtcgctta gttttgagta ttaaggaaaa
    10081 ttttgtgaaa atgtctttcc acatttttgc ataaatttga cttaataccg agaaactgac
    10141 ttttgaacac cgtcgataag gttgtttttg aagcgctttg cctcgagtat taaggagaaa
    10201 cattttcaaa atagcttctc atattttgaa atgtaatgac ttaataccga gaggcagctg
    10261 ataaaacacc gtcaataagg ttgtgaaaaa gctggtctgc atcaagcatt aaggactggt
    10321 tgtgaaaaat agctctccat atttttcaac aggctggact taatgccgta gatgcaagct
    10381 tttgaacacc atcgataagg ttgtttttga ggcactttgc ctcaagtatt aaagacaggt
    10441 agtaaaaaag ctgatctata acttgcaatg aatttgctta acccatattt tccagacaga
    10501 acaaaaaagt ttttagtttt ttaaataaga aagaaacact tggaatcact cttttctttc
    10561 taagtatttc tttcttgatt ttttgtcttt tttcaaaatt tttcgctacg aaaaagaaag
    10621 aatatttata tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt
    10681 aagtttgtgt aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta
    10741 ttgggatccg gacttgtcag tatcctgctc tttttatctg gctgcgtgcg gatggattca
    10801 aacggaaacc ctgacacttc aggaatcgtt tatcgagtac tcgtccatcc tatgggccaa
    10861 gcgattacat atctagttga gaatttcaat tggtcttacg gctgggcagt tattgcaatg
    10921 actgtgatcg ttcgtatcat catcttgcca ctaggtatca gtcaatcgaa aaaaacaatg
    10981 atccaatctg aaaaaatgca agcgttaaaa ccacaagttg aagcagcaca gcaaaagcta
    11041 aaagctgcaa caacacgtga agaacaaatg gcagcacaag cagaaatgca gcaagtatat
    11101 cgcgaaaacg gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg
    11161 ccgatcttct ctgccttgta ttttacggct cgctacacag aaggtatccg tgaatcatct
    11221 ttttacggca tcgatctagg ctcaccaagt atggtgcttg ttgccattgc aggggtcgct
    11281 tatctgcttc aaggatatat ttcaacaatc ggtattcctg aagaacagaa aaagacgatg
    11341 cgtacgatgc tgatcgtctc tcctgctatg atcgtcttca tgtcgatcag tgcgccagcc
    11401 ggtgttacac tttactgggt agtcggtggt gtgttcagct gtctgcaaac attcatcaca
    11461 aacgttatga tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaacccg
    11521 ccaaaacaag tcgtcactcc aagaaaagac gtgacagaat cagcaaagcc agctaacaac
    11581 aaacaagcaa caaaacaaat caaacaacca aaaaacagta caaacaacaa aggccgcaac
    11641 gcaggaaagc agcagaagcg gaagtagata gtaaataaga gtgtaataaa aattcattaa
    11701 cagttttagc aattaaaaat atcgaccaag atttttgaaa aagaaatctg gtcgatattt
    11761 ttatttaagt gaatgtttaa tttgaatcat cgattgatcg ctatctaatt gcagcagcat
    11821 ctttttatga agaaacaact ttttcttatc tatcaacgta gacaggtgtt gctgtttctt
    11881 ctaatagtgt acttaattcc ttaatatttt gttttccttc ttctaacatc caactactcg
    11941 ctttttcttc gccttcggta acaaaaggcg ccactccctt cgcccatgtt gctcgcccac
    12001 ataagacacc attgaatgtc gaacctgatt gttttgcaaa acgtaatgta tcttgaaata
    12061 gcgtagcatt gactcccgca cttaaaaaaa taaacggttg ttcagtcact ttcgattgtt
    12121 catagaaata cgcggatgcc tctgcttgac tataacaagt ctcttgccca tatccttcca
    12181 caaatctcat attcactggc acttctactt tcaatacatc cacttgataa cgttcttttg
    12241 aaaattctcg catggcttca ataactttat gtggttttac ttttgcatag gcaagagaag
    12301 acggatcgcc aatagttgca tcataagaga ggatctctaa aaagaaaggt atgccttctg
    12361 cttcgcattc tgaaccaatc cgttctataa ctatttgttt ttgcacatta atctctgctg
    12421 gttcatcaac gtcatagtac aataaaaatt tacaagcatc cgcaccagct tcttttaacc
    12481 ttttcaccga ccaaatattc aataaatcag gtaatcttcc cggaattttc gtatcatagc
    12541 cggttttttc ataagctagc agcaagccac attctttctc tcgaagcgct gctgcaggca
    12601 ggccgtattc tggatcaagt aaaatagctg aggcataggg agtcaggtat tgagaaacca
    12661 tctgtttaaa ttggatgatg tcttctgatg tagcttcttt atattggttg atcattttct
    12721 tcaaagcacc acgctggtcg attgctaacg cgctaataat tccagcttca tccgtcaatc
    12781 gcttcaaacg ttcctgcttt tctatactca tcttcttcat agatcttcac ctatttcttt
    12841 agttaatatt gtggctattt ttgtttttga ttttgctttt ctcaactgtt ctgtaacctc
    12901 ttttcgcatc aatgatcgtg caacgagaga caataatttc aaatgagtcg ttcctgcttc
    12961 tgaatctgga ataaataacg caaaaataaa atcaactgac tgtctatcta aactgttcca
    13021 ttcaattcct ttgttcagtg tgacgataat catactaggt tcgttgattg tttgagactt
    13081 cgcatgagga atagcaaaac ctgacattat tcctgtagta ccttcttttt ctctttctag
    13141 aagtttttga tatacatctt tttcgtcatg agcaattcct aagcagaatg tttgctttgc
    13201 taaaaactta aatgcttctt cttgactatc caatggctgt tgtaaaaaaa tgttctcttc
    13261 atgaatgatt gtcatgataa gtctcctgct cttccttttt cgataactgt acgatttgct
    13321 gctttactat catccatctt cttgtcttta tcagttactc ttttcttttg gattaatcct
    13381 agtatcactc caccaacgat cgaaccaata agaatcgctg taacccattg gatttttcct
    13441 gttactacag gtaatactaa aaaaccgcca tgtggtgctg gaacttggac gccaaacaaa
    13501 taagtcaaga cagcagcaat tgatgagcct aacatcatcg tgggtaacac tcggatcggg
    13561 tctttcgcag caaacggaat agctccttcc gtaatatgag ttgatcctaa aataaaatta
    13621 accaaacctg cattacgatc attggtatca aaatatttac caaacaataa agtagcaaaa
    13681 ccagtaatca acggtggcgc aatacaagct gctgacacac cagccataaa agtcgtgttt
    13741 ccttgtgcca aaagagctgt tcctgttaca tatgccgcct tattaaccgg tcctcccata
    13801 tcaaacgcac acatgcagcc aacaatcacg ccaagaacaa gtggattcga atgttcaaat
    13861 ccagctaaaa agctcatcat tccttcattt atagccttca ttggacctgc cagcaaagac
    13921 atcacgatgc caataaatgc tacgccaata actggatata agaagattgc cttcaagcca
    13981 tctagttgtt taggtaaaat tgtcagtagc ttttgcaaaa ataagataaa ataacctgct
    14041 aagaacccag ctaaaatacc tcctaaaaat ccagtaccgc cattcatggc tacgattcca
    14101 ccaacaaatc caacgattaa ccctggacgt ttcgcgatcc cttctgcaat ataagctgct
    14161 aaaactggaa ccatcattcc cattgatgca tcgccaactg cttttaccat tgccgctgta
    14221 gcattgtatt gtgcatgatc tggatcaaaa gaatagattc cccaaacggc aaatgaaata
    14281 gcaatcaata ctccgccagc taccacgaaa ggcaacatat gagagacacc gttcatcaaa
    14341 tttttataga tgctacgacc aaaattagca ccactcatcg cttctggttc taaagtatca
    14401 gcagcttcat tatctgctaa gacagtacct tttcctgcca atgcttcgtc aatcagccgt
    14461 tgtgcatcct tgattcctgt actgacagaa acatcaatga ctcgttttcc cgcaaatctt
    14521 tctgaatgga catctttgtc tgcggcaata atgacagcat ctgcctgttt gatttcttca
    14581 gccgttaatt cattttcgat cccaatttgt ccatgggtct ctactttgat cgtgatgcct
    14641 tttttcctag ctgcttgttc taatgcctct tgcgccatgt aggtatgcgc aattcctgtc
    14701 ggacaaccgg ttgctgcaat tagttgatat tttcccatct ttcgaacctc tcttccctga
    14761 ttttgatttg tttacttaat tcctccacat ctaaaaaatc tgttaatcct ttgcgaaaag
    14821 cggttgagct gcctgctgct atgcttttac gtaacgtttc atcaagcggt cgtcgattca
    14881 tgtatcctgc taaaaaagcg cctaacatgg tatcacctgc acatgctgta ttgacaactt
    14941 ttccttttgg cgagtttcct cgaaacaccc tgtctttcgt aaaaagaatt gctcctttct
    15001 caccgaggga taacaaaaca ttttctgcac ctaactctac tagtcgttgt ccataaacaa
    15061 agtaatcttc atctgtaacc atttttcgtc cgaaccaaga agaaagttct tcctcgttcg
    15121 gtttcagcaa aaatggtcga tagggtaaac aatccatggc ttcttgatca ctactatcaa
    15181 taatcaaatg aatccccttt tcctgacaaa tccgactgat ttctattaaa acctttggag
    15241 acagccctct tggtaaactc ccagaaacac aaagataatc ttctgcttgt aatgctctta
    15301 tttgatttaa aaaattatgg acagctgtct gcggtatttc aggtccttga ttcactaatt
    15361 tgtattcttc tcccgtttga ttgacttgtg taaatacatt gatacgcgtc ataccaggca
    15421 cttcaataaa ctctgtttgg atttgtttct gctgtaaata gtcttctata tactttcctg
    15481 tgaacccagc agaaaaacct aatgccgtac ttgggaaatc tagcatcttt aatactagtg
    15541 acacattcac tccttttccg tttgcctgaa tgtcatcctc ttttgtgcgg tttaccataa
    15601 aaggatgcat ctcctctgtt tcaataaata gatcaattgc caaattcatc gtgcatgtgt
    15661 agatagacat aaccaatgac ctccttgact ctattatgaa atacgcgaaa gagaaaatgt
    15721 tttcttaatc gttccaacac aaagaaaacc tttacattta taaactcgtc gtgctatttt
    15781 ttaactaact tttggtgaaa gaaggaaaga atatggatca caaattaagt gaaacagaac
    15841 agtacctctg gaactttatc gaacaccata tcctagagat ccctaactac tccatcgtga
    15901 aactaagtga acaagcaaat gtctcaacag ccaccattgt gcggacaatg aaaaagaaag
    15961 gctatgaagg gtttacttcg tttaagcatc atctaaaaga aggagaaaac aagaacatca
    16021 atttttcttt cttagataaa gtagacaaag gtatccgccg agccattcta aaaaatgaac
    16081 aagaagtggt acgtacgatc aatgtgttgg aaatcggaaa tattgaggat gcgatacaaa
    16141 gaatcaaatt tgctgaccgg gtttttgtct ttgcccgagg attttcagaa atgattggcc
    16201 aagaaatgct ggtaaaactt caattaacgg gaaaaaattg tcaaatgcat actgatccag
    16261 aaattatcaa aagcatcagt cagaaactga ctaagaaaga cagcgttatt tttgtttctt
    16321 tgaacggcga gacaaaagaa ctcgtcaccg ccgcaaagaa ttgctatgat gcagagattg
    16381 gttcgattct agttacagcc aatcattcct ctacactgaa agactattgc gagatcaatc
    16441 tcgtaggttt caaatcagaa ggttcttatt tccctgatta tgaagtacgg tcacgcttgc
    16501 ctctccagat tatcgcgaga attctgcttg acgcctatgt attgcgtatg ggggagaatt
    16561 gagaagcagt ttattatggt tggttacagt ttaaaacatc acatttttta ttctttatat
    16621 tgtatagact cacgtaaact ttttatgtat aaagttattc acaatctata aagttacttt
    16681 aagtaacaaa aaataattga aaatacttaa aatcaaaaaa tatcttttta atcaataaaa
    16741 aaattgacag ttttattaat aataagctat tctgttatag aagaaaaaat tgtttgttat
    16801 tattagcaac aaaaaaagga gtgcatcatg aaaaagttat ctcaaaaacg tttagctcaa
    16861 atcattattg attctagaaa atctctgaaa atgacacaac aacaacttgc agtagctact
    16921 ggtatcaacc gtgccttaat tagtcgatta gaatctctcg attttatccc gtcaatacaa
    16981 caattagaat cattagcaga agttctaaat tttgaaccaa cagatctatt tataaatgaa
    17041 tcaaataaat caaacagaac aaaacatcag tcgaagaata ttgctgtagc cggtactggt
    17101 tacgtaggtc tttccattgc tactcttctt gcccagcaca atcaggtaac agcagtagac
    17161 attcttcctg aaaaagtaaa acaaattaac aataagaaat ctccaataca agacgattac
    17221 attgaaaaat atctagctga aaaaaatctt aatttaattg caacgactga tggtgcagcc
    17281 gcctatagag aagccgattt tgttgtcatt gctgctccaa caaattatga tagtaaacaa
    17341 aattattttg atacttctgc tgtagagtca gtaatcaaat tggtgttaga agtcaatcca
    17401 aaggcaataa tggtcatcaa gtcgacggta cccgtaggct ataccgaaag tattcgtaaa
    17461 aaatacaata ctaaaaatat tctattcagc ccagaatttc tcagagaatc taaggcatta
    17521 tatgacaatc tatatccttc gcgaattatt gtcggcacgg accaaactga caaaacttta
    17581 cgagaagcct ctcacacttt tgcagattta ctccaagaag gagcaatcaa aaaagatatc
    17641 gaaactcttt tcatgggatt cacagaagct gaagcagtta aattattcgc taatacttac
    17701 cttgcacttc gagtatctta cttcaatgag ctggatactt atgcagaaat gaaaggacta
    17761 aatacacaag aaatcattca cggggtttgc ttagatccaa gaattggcac acattataat
    17821 aatccatctt ttggatatgg aggctattgt ttaccgaaag atacaaaaca acttctcact
    17881 aactataacg atgttcctca gaatatgata agtgcaattg tcgatagtaa tcgtacaaga
    17941 aaagacttta tagcagatcg agtgttagaa cttgctggca cgtatgaggc taacagttcg
    18001 tggaatgcag aaaaagaaaa agaggtagtc ataggtgtat accgtcttac aatgaagagt
    18061 aattcagaca acttccgtca gtcatctatt caaggagtta tgaagcgaat taaagcaaag
    18121 ggggcaacta ttgtaattta tgaaccaaca cttgaaaata acactacatt ttttggttca
    18181 aaagtaataa ataatttaga tgattttaaa aatatcagtc acagtattat tgctaatcgt
    18241 tacgatagta atcttgatga tgtaaaagaa aaagtatata ccagagattt atttcaacga
    18301 gattaaaaaa taacacctca gatttgtagt gtctgaggtg tttctataaa cttttataag
    18361 taaaaaaata caattatact tcataaaaag acttatacca ctgcgcaaat ttacgaagcc
    18421 cgtcacgcaa acttgtactt ggtttaaatt caaaatctcg ttctaacgca ctagtatctg
    18481 cataagtaac tggcacatct cctggttgca ttggaactag ttcggtatga gattcaaagt
    18541 cgtaatcttc tggtagcacc cctgctgcaa ttagctcttg ttgtagaata tctacaaaat
    18601 ctagtaggtt ttccggcgta ttgttaccaa tattataaat atgatatggt gggattggta
    18661 gcccatcttc cccatcaatt ttctctggag cgcactgcat aaccctcttt actccttcaa
    18721 caatatcatc tatataggta aagtcacgct tgcaattccc ataattgaat atttggatat
    18781 tatcaccagc acgaagttta tcagtaaaac caaaataagc catatctgga cgcccagcag
    18841 gaccatatac tgtaaagaaa cgtaaccctg tagacggaat attgtaaagt ttagaatatg
    18901 catgtgccat tgattcatta cttttcttag ttgctgcata caacgatact tgattgtcta
    18961 ctttatcctc tgtagaataa ggaattttct tattagtacc ataaacggaa gacgatgagg
    19021 catacactaa atgttccaca ccagattctc cattatcata tgaatgacga caagcttcaa
    19081 gaatattata gaatcctatt atgttagatt cgatatacat atctggatta gtaattgaat
    19141 aacggactcc tgcctgagct gctaaattca ccacgatact tggtttataa ttatcaaaga
    19201 tgaaatcaat tgttgcttta tcagcaatag aacctttgat aaaattccaa gtagatcctg
    19261 gatggttctt tgcctccgtt tctatctctg ataatctata gttcttaata gagacatcat
    19321 agtaatcatt catattgtca atgccaatga tttttattga tgactgagta cgtaataact
    19381 caagaaccaa atttgatcca ataaaaccgg ctgcgccagt tattaatatt gttctatttg
    19441 ataaggacgt gtttaattcc agcatttttt agcactcact ttcttttttt cttatgaata
    19501 catatttgtt atatattaaa aaatcttatt tagacttatc tattgtcact tttatcattc
    19561 taatctttgc acgtagtaga ataattatac agataggaaa ttgctaagca acccacttct
    19621 ttctattatc tattaactta ttctaaaacg aatagaaatt attcttgatc acataagtaa
    19681 ccttaaaaga aaaa
//
LOCUS       DAXLPQ010000049        19155 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.049, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000049 DAXLPQ010000000
VERSION     DAXLPQ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.049"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            87..2876
                     /locus_tag="ACF3UO_002082"
     CDS             87..2876
                     /locus_tag="ACF3UO_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFD3658054.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            2923..3450
                     /locus_tag="ACF3UO_002083"
     CDS             2923..3450
                     /locus_tag="ACF3UO_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFD3658055.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            3471..4661
                     /locus_tag="ACF3UO_002084"
     CDS             3471..4661
                     /locus_tag="ACF3UO_002084"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3658056.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            4701..5999
                     /gene="asnS"
                     /locus_tag="ACF3UO_002085"
     CDS             4701..5999
                     /gene="asnS"
                     /locus_tag="ACF3UO_002085"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFD3658057.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            6929..7603
                     /locus_tag="ACF3UO_002086"
     CDS             6929..7603
                     /locus_tag="ACF3UO_002086"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3658058.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLIAQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            7600..7941
                     /locus_tag="ACF3UO_002087"
     CDS             7600..7941
                     /locus_tag="ACF3UO_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658059.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSFFAQF"
     gene            7971..8330
                     /locus_tag="ACF3UO_002088"
     CDS             7971..8330
                     /locus_tag="ACF3UO_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFD3658060.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGISLIVNIIWLIISGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            8855..10936
                     /locus_tag="ACF3UO_002089"
     CDS             8855..10936
                     /locus_tag="ACF3UO_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3658061.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            11247..12713
                     /locus_tag="ACF3UO_002090"
     CDS             11247..12713
                     /locus_tag="ACF3UO_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3658062.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            13328..13867
                     /locus_tag="ACF3UO_002091"
     CDS             13328..13867
                     /locus_tag="ACF3UO_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFD3658063.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            13941..14381
                     /locus_tag="ACF3UO_002092"
     CDS             13941..14381
                     /locus_tag="ACF3UO_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFD3658064.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            14394..14603
                     /gene="copZ"
                     /locus_tag="ACF3UO_002093"
     CDS             14394..14603
                     /gene="copZ"
                     /locus_tag="ACF3UO_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFD3658065.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            14603..16789
                     /locus_tag="ACF3UO_002094"
     CDS             14603..16789
                     /locus_tag="ACF3UO_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3658066.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            16809..18980
                     /gene="copB"
                     /locus_tag="ACF3UO_002095"
     CDS             16809..18980
                     /gene="copB"
                     /locus_tag="ACF3UO_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFD3658067.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6399 a         3343 c         4181 g         5232 t
ORIGIN      
        1 ttctttaaaa agcgatgaga gtatttttct gcactttgta gtataatttc aaaagaacat
       61 tagaggcagg agaagaggaa gatattttga aaccaagaac ttatgcagtc gttgatatcg
      121 aaacgactgg gacgaatcca aaagaagatc ggatcatcca atttggctgc gtcatgattg
      181 aatcaggtcg gatcacttca cgtttttcga tcgatattca tccagggcgg aagatttcaa
      241 aacaaatcca gcatttaaca gggatcacga atcaacgcgt ccaaaaagcg ccttatttcg
      301 aagatgtcgc ccaaacgatt tacaatcttt tggcagacac catatttgtc gcgcataata
      361 tttattttga ttataatttt ttgaaccatg aactcatgcg atgcggactt cctagtttga
      421 agataccagg catcgataca gtagaacttg cacaaatttt cttgccgacg gaaccaagct
      481 ttcgcttagc tgatttgtca gaaagccttg gatttattca tgagaatcct catcaggcag
      541 atagtgatgc cgaagtgaca ggtcaacttc ttttgctgat cgaagaacgg atgagaaaat
      601 tgccaatcat cacgttagag cagattgcgc gattaagtag acacacaggt atggatacga
      661 gtcgtttcat ttatcatgtg attgaagaaa tgaaagaaaa accagagcca cttgatccct
      721 cattagaaat cgtcgatggg ctagctttgc agaaaaaaga agtggaacta ttcacatccg
      781 tccattatgg tgagcggaca tatccaagaa aaaaacaagc aaaagaaaaa atgtttggta
      841 aaacactgat gtatcgaaaa gaacagaaca gactgatgaa tgcggtctac gaccatttca
      901 caaaagatga atcaaaagat ttgatgatcg aagcagctac aggaatgggt aaaacaatcg
      961 gttatctgct gccattgagt tatttggcta cacctgaaaa acccgctgtc atcagtaccg
     1021 tttcgctagt tttgcagcag cagatcatag aaaaagacat tccattgctg aatcaattgc
     1081 tagatcagcc catacaacct gtaattatca aaagctatcg ccactatatt gatttacagc
     1141 gttttaaagg cacacttgtg gaaccgccag aacaaaaaca atatgctttg tatcaaatgg
     1201 cggtcttagt ttggctgacg caaacgaaga ccggtgattt ggatgaatta catttaacaa
     1261 atttgaacca ttcattcttt gcagatatcg cgcacagagg tattggattt ttagcaagaa
     1321 atcagtcatt ttacgaacaa gactttgttc gtttcttgca aaagaaaatc aggcaaagta
     1381 attttttgat tgtcaatcat gcgtttttaa tacaagaaac acagcgaaaa gaaccattgc
     1441 ttccagctag tccatttttg ttgatcgatg aagtacatca tttgccggaa atcgctgaaa
     1501 aagtaaatga caaacgatta agtattaact atttccataa acaaatccag caattagaag
     1561 aaccaaatca gctgtttgac cgaatacaaa gctatttacc gaaagaacat gaagccttac
     1621 gctggttatc gatttatcga gaagaacttt ctgcgctatg cgaagcacag atttgtatgg
     1681 cagaaggatt aatgagttta gtgagcggca agcaacctaa cggacagtat ccagaagaag
     1741 tcatgatgac aaaagagatg ttggatcagc tgccactgga atctgggaca gccattgatc
     1801 acctgcagct tttttatcag gagatccagc agctacagtc acaaatgcgt ctgacttttg
     1861 agattatcca agaaagctgg acaaaccaga tgcggatcga tttagcaagt ttatatagct
     1921 tatttgatca attagacaag cagtacttgc tgatggatca atggctggaa gactggcgag
     1981 atcatttgat ccattggttc gttcctggga acacagcgca gcagatgatt tttcatctcc
     2041 atgattttca agcggctatg ttgccgtcga ctgtttggta tcctcgatat gatcgtattc
     2101 tttatattgg aggaacgctg aagatcggcc ctaatcgaca ctatctctct aagcggcttg
     2161 gcattgaagc agcacctctt aaagtgattg cctctcctta tgattatgag aaacaggcaa
     2221 ggatctatgt gccaaaagag gcacctgccg tccatcaagt cagcaatcaa gcatatatcg
     2281 attatttaga gacagcactt acaggtctga tcgaacaaga agatcggcca atacttgtgt
     2341 tattcacttc tcatgatgtt ttgcagaagg tctatcagaa aatgcatctg tctatgctag
     2401 aaaaaggacg agaaatacta gctcaagggt ttggcggaag ccgggagaag cttttgaaac
     2461 gcttcatttt gtcagaaaaa agcgtattgt ttggcgctga cagcttttgg gaaggtgtag
     2521 atttgcctgg agatgctttg cagatcgttg tagtcacacg tttacccttc gataatccgc
     2581 ttcgcccgat ggtcaaagct aggaacgctt atttagaatc agaggggatc aatccttttt
     2641 accaggaatc cgtacctaaa gcagctttga agttacgcca agcattaggt cgcttgataa
     2701 ggacggagac agatcgtggc gtattgctta ttttggatcg aagactagtc actgcaaaat
     2761 atggtgcacg gatcatccat gcattaccga aaaaagtacc gatcaaagag ctagctatgg
     2821 aggaaatcta tcaggacatc catgaattct taaagaaaaa tgaagaagga agttagagga
     2881 gctgtctttt ttcataatta aaatctgcta taatgaaaag gaatgaagat aaaggagcga
     2941 cgacccttga agaaaaaaca gacaaaggaa aaaacgatta atcgcgtgtt acttggcttg
     3001 atcgtatttt tattagcggt catcgtgatc agctcgattt tttacttgcg ttccagtcgt
     3061 ccggcggtgc aggcgaagaa agaagcagta gaaatcgcaa agaaatatgc aaatcttgag
     3121 gaagccgatc atttttattg gtttactcga aagaagacat acttttcact gacaggtaca
     3181 aatgataaag gaaaagaaat cgccgttatc attcctaaat ctggtgaaaa agtaaaagta
     3241 ttggatcaaa caaagggact gactgaaaac gaagcaaaac agacaattgc tgcggcccat
     3301 cctgaaatcc aaatcgaaaa agctgcttta gggatgtatg atgatcagcc tgtgtgggaa
     3361 gtagtaggaa aagaaacaaa tgggaaactg aattattacc tgattggctt tgaatctgga
     3421 gatgaagtca agacaatcaa gggaatttaa aaggtaaagg aatgaatggg atggagttat
     3481 caaaaagaac aaaacgatta gaaccgtctg tcactttggc agctgcggca aaggccaagg
     3541 cattaaaagc aaaaggcaga gatgtgctga gtttgactgt gggagaaccg gattttgcga
     3601 caccagaaaa catccaagaa gcagcaatcg aagcaatccg caatgggaaa gctagctatt
     3661 atacaccaac agcaggaatc ccagagcttc gacaggcaat cgttgattat ctgaagaaaa
     3721 actatggact tgtctatgaa ccttcacaaa cagtcgtaac agacggagcg aaatttgctt
     3781 tgtataccct tttccaaacg atccttgacc cgcaagatga agtcatcatt cctgtgcctt
     3841 actgggtcag ttacggtgag caagtaaaac tggcagaagg acttcctgtc tttgtgaaag
     3901 gggaagaatc caatagctgg aaagttactg ttgagcagct agaacaagca cgttcagaaa
     3961 aaacaaaagc cgtaatcatc aattctccat cgaatccgac tggaatgatt tatagcaaga
     4021 atgaactgca ggcaatcggt gaatgggcag taaaaaatga tattttgata gttgctgatg
     4081 atatttatgg tcgtttagtt tataatggca atgagtttac tccaattgca acgatttcag
     4141 aagcaatcaa aaatcagacc atcatcatca acggcgtgtc taaaacatat gcgatgacag
     4201 gctggcgcat tggttatgcg gtggggaatt ctgagatcat caatggaatg atcgctgttg
     4261 cttcccagtc aaccagtaat ccgacagcag tcagtcaata tgcagctgtt gaagcattga
     4321 aaggcgagca agatacagtg gaagaaatgc ggaacgcctt tgaagaacgc ctgaatacgt
     4381 tatatccgct tgtggcagaa ctgccgggtg tttctcttga aaagccgcaa ggagcttttt
     4441 atctttttcc taatgtaaaa gaaacgctac gcatgtgtaa atatgaaaat gtcacacaat
     4501 gggtagaaga tcttttagaa gaaacagggg tagcgcttgt gactggcgaa ggctttgggg
     4561 caccagaaaa tgtccgcatg agttatgcta ctgatcgcgc tacgttagaa gaagcggtac
     4621 gcagaatcaa gcaatttatt gagagtaaaa gtcaaaatta atcctgaaga aattcaagga
     4681 atataaaagg agagtcatac gtggaacaaa ttcaaatcat cgattcgaaa aaccatgtgg
     4741 gagaaacagt aacaatcggc gcttgggtcg caaataagcg atcaagcgga aaaatcgcat
     4801 ttttacaatt aagagacgga acagcctttt tccaaggtgt agttgtaaaa agcgaagtgc
     4861 cggaagaagt tttccaaaca gctaaaaatc tacaccaaga aacatccgtg ttagtaactg
     4921 gagaaatccg tgaagacagt cgttcaaaat ttggttatga aatcggaatt acaaatgtgg
     4981 aagtggtaag cgagagccac gattatccga tcacaccaaa agaacacgga acagacttct
     5041 tgatggatca tcgtcattta tggctgcgtt cttcaagaca acatgcgatt atgcagatca
     5101 gaaatgaaat cattcgtgca acgtatgaat tctttaatca acatcatttt gtcaaaatcg
     5161 atccgccgat cttgactggt tctgcaccag aaggcactac ggatctattc gaaacaaatt
     5221 actttgatca aaaagcttat ttatctcaaa gtggccaatt atacatggaa gctgctgcta
     5281 tggctttcgg aaaagtcttt tcattcggtc cgactttccg tgctgaaaaa tcaaaaacac
     5341 gacgtcattt gatcgaattc tggatgatcg aaccagaaat ggctttcact catcaagaag
     5401 aaagtttaga agtacaggaa caatatgtag cattcttagt acaaaatgtt ttagatcatt
     5461 gcgaatacgc attagatgta ctaggacgag acaaagaagt cttaaaaact tatacaaaat
     5521 tgccattccc tcgtattact tacgatgatg caatcgaatt actgaagaaa aatggatttg
     5581 atgacatcga atggggcgaa gactttggtt cacctcatga aacgttcatt gcgaattcat
     5641 tcgaacagcc tgtctttatc ctaaactatc caaaagccat caagccattc tacatgaaac
     5701 cacatccaac aagagaagac gtggtgatct gtgcagatat gatcgcacca gaaggttacg
     5761 gtgaaattat tggcggaagc gaacgggcaa cagactatga tttcttgcta gaacaaatcc
     5821 gtaatcacgg tttggatgaa aaagaatatt catggtatct tgatctacgt aaatacggtt
     5881 ctgttccgca ctctggtttt ggtctaggcc ttgaacgaac agtcacttgg attgctggta
     5941 tcgaccatgt gcgtgaagct attccattcc cacgtttgtt gaaccgaatt tatccataag
     6001 aggttgtgaa atcagtgcct tgacctgagt attagagaaa caaaacggaa aaatagcttc
     6061 tcatatttta ccgttttttt agctaatatc gagggtcagc tgattgaaca ccgtttatat
     6121 caagaggttg tgcgcctgcc gttcagctcc gagtcacaag gagtaatttc aaaaaacagt
     6181 ttttcatgtt tgatgactat tgtgacttgt gaccgaggag ttggccggag agcaccgttt
     6241 attctaaaaa agaactgcga actctcgcag ttcttttttt taaatacggg ataaaggaag
     6301 tttccagcag acaagagaag aaagcaaaag aaattgctat ttgattcaca aggttctata
     6361 acgaaatcgc aatcaatcaa acatttacaa agaaggtaat tcaaatggaa atctaatttg
     6421 atgatgcttc tgctgttgaa ataaagcatc atctagcacc tgaaaacaaa ctaatagtaa
     6481 cattcgaaga tggagtaggt ccgtattttc agcatgcaat aatccatatg taagttcaat
     6541 tcacccttga aatcatcgga ccagataaag ttatgaccaa tctatcccaa gcaatctaga
     6601 agagatatta gtaaagggac atttactaga agtcttagat gagcctataa atatatgttt
     6661 tgatggcgtc atcagtggtc tgattgacgg aagcttgggt atgatcgatc tctctggacc
     6721 aaacaacgaa ggaatcaagg ggaatccggc acgttaagaa aaaaatagca taaaaaacta
     6781 gacacttgat gagcgttcat tcaattgttt gaagggacta ggctgatgtc attttttata
     6841 catatatttt ctctttcgtc ttgatagggc ttatgggata atataaggaa gaaaatcatc
     6901 gttttattca aaaaggagtt tttgacaaat gaaaaaacgt atattattta tcggtgatag
     6961 cattacagac gcaggaagag accgagcaga agcaactgat ctaggtaaag gttatccact
     7021 tttgattgcc ggaaaactaa tcgcccaata tccaacgatg gaatttgaat gcatgaaccg
     7081 tgggatagga ggagacaaaa ttgcagatct gcaagtacgc tggcaagaag attgtttagc
     7141 tttacaacct gactatgtat cgattttgat cggaatcaat gatacctggc ataatactag
     7201 cgatcaggct atattcggaa ctgagaaatc tgctcagcaa tttgaatccg tttatcgaaa
     7261 attactaaat gaacttcaaa cagcggaaat ctgcaacatc atcttgatgg agccgtttgt
     7321 acttcctata accgacgacc gtcatggctg gcgtaaagac ttagacccta aaatccaaat
     7381 tgttcgtaaa cttgctaagg aatatggcgc attgctggtt cctttagatg gtatattcaa
     7441 tgctttaggg attgcttatg gtttttcgaa atatacaaga gaagatgggg tccacccaac
     7501 gattggtgga catgagatca ttgcacaaag ctggatagat gcaattgccg cagtcgattt
     7561 ttttagtgga gataaaaatg agcgaaagaa aagtgaaaaa tgatggaaat aaggtgggca
     7621 gtaaaagaag atttacctca aatcaatcag ctgattactg atcatccaga atcattcgta
     7681 aaagcaaaaa cggcagctga cctaaatgat aagaataaac tattgctcgt tgctgtaaca
     7741 aaagaaaaac ggattatcgg atttgcgcaa gcggacgtgc aacagtcaga agaacgattg
     7801 gatcagcgac catcaggaaa actaatccaa cacacattag taacaaaaga aaatacggaa
     7861 gaaatccaaa aaaaatttgc agaatatttg atgctggaag ctaaaaaaag aagaataaaa
     7921 tcattttttg cccagtttta atcaaaaaca gtaatagaag gagaaatata atgagttgtt
     7981 taggaaatgt catctggttt atattcggcg gactaatcgg tggtcttagc tggttagcag
     8041 cggggatact ttggtgtatc acgatcatag gtatcccaat cggtatgcaa tgttttaaga
     8101 tcgcctccct ttcttttgcg ccttttggca aagaagtaat ttatcaccag tctggcatat
     8161 cattgatcgt taatatcatc tggctgatca tttcaggcct accaattgct ctcgcacatg
     8221 tcgtcagcgg catccttcta tgtatcacga tcatagggat accttttgcc aagcaatctt
     8281 tcaaacttgc tcgattggcg ttgatgccat tcggtgcaga aattgtataa aaagagaata
     8341 ataaaggtta gaaaacgcat agagtcaggt gggatacatg tatttcacct gactctatgt
     8401 gttttcctgt ataagttctc ccatgtgact tttacgtctt ttatttatat gggattactg
     8461 tttatggaaa gttgaaataa ttttcattaa agaactcttg ctatattttt gaaagcttag
     8521 tggagcttcg aatatctggg aaggacattt tgcagggatt gaaaaaagat attgtcctat
     8581 cgaaaaatta atgaatttag acaaattgcc agcaacaggc ttcaaactta gttgctatcc
     8641 tgtcaagatc aagaaggcaa gtgcgggttg gataagagca gtggcaatga tcgaaaagaa
     8701 aaagaaagaa taagccaaaa catctgtatg gaagaaattt tccgatgcag atgtttttca
     8761 ttttttcttt cggatacctt gacatatgaa taaccgttca tttataatta gttatgaaga
     8821 gatattcata tgttgaggcg aggaggtcat taaaatgaaa agttacagat tagaaggttt
     8881 agattgtgcg aactgtgcaa tgaaaatcga aaaaggagtt cagaagatca atggagtcaa
     8941 ggaagcaacg gtaaacttca cttctggaaa actaacgatt gacgcagagg aagatcattt
     9001 ggctacgatt gaacaagaaa taaaaaaagt agtgaaggaa ttagaaccag atgtcaaagt
     9061 aacagaaata gataaggaaa aagtatctga acatggaaat gaaaaagaga gaaatacgct
     9121 gttccggatt ttattttccc ttgcaggtat cgctttattg ctattatttg attttaatga
     9181 accaattcgc ttgatagggt atttattgat ttatctgctg ataggatatg atgtagtgaa
     9241 gaaggcagtg atgaatatcg tcaaaggaaa aatctttgat gagaattttc ttatgtctgt
     9301 tgctacgatt ggcgctatgt tgatcggtga atatccagaa gccgtagcag tgatgctatt
     9361 ttatcaaatc ggcgagtatt tccaaggatt ggcagtcagt cattcaagaa aatcgattcg
     9421 cgaattgatg gcgatccgtc cagaaacagc tcacgtgcag acgacggaag gattgatgac
     9481 cgtgaaccct gaagacgtgc agatcggtca gtttgtactt gtgaagcctg gtgaacgtgt
     9541 accgttagat ggaacgatca tcgaaggaga atcattagtc gatacgtcag cacttacagg
     9601 agaatcagtc cctaaatctg tatatgttgg tgaaacagta ttaagtggat ttatcaataa
     9661 aaataaacca tttttagttc aagtagaaaa atcttatgaa aattctacta tcagcaaatt
     9721 attagaatta gtagaaaatg ccagcagtaa aaaagcacca gctgaaaatt tcattactaa
     9781 attcgcgcgc tattacacac cagtcgttgt aggattggcc gttttattag ctgttttacc
     9841 tccacttgtt gtttctggag cggcgttttc tgaatggatc tatcgagcat tgacattttt
     9901 agtgatctca tgtccatgtg cattagtgat ctccgtaccc cttagtttct ttggcggtat
     9961 cggaggagca agtaaaatcg gtgtattagt aaaaggttca aattacttgg agttgcttgc
    10021 acaaactgag acagtggtat tcgataaaac cggcacatta acgaaaggtg acttttcgat
    10081 ccagacgatc gatacaaaaa tcgatccaaa gatattcatg caatatgttg cgagtgcaga
    10141 acagttttct acacatccga ttgctcaatc tgttttagaa ggctacgcag gtccgctttt
    10201 accaacagct aatatccaag aatttgcagg tgaagggatc ttagctgaag ttgatggcaa
    10261 acaagtatta gcaggtaatc acaaattgat ggaaagattt gaaatctctt ttccttcaag
    10321 tcaagaaatc ggtacattgc tttatctagc gatcgatcaa agttacagtg gttatcttgt
    10381 tattgcagat accttgaaag aagatgccgt agacgcattg gttcaattaa aaaaggctgg
    10441 tgtgaagaac acagtcatgt tgacgggcga ttcgaaaaaa attgctgatc atatcgggaa
    10501 gcaagtaggc gtggacaaga tatatagcga attgcttcca gaagataaag tgcagcggtt
    10561 agaggaaatc ttacaaagaa acaataaaaa gaccgcattt gtcggagatg gaatcaacga
    10621 tgcaccggtg ctagcaagag cagatgtagg aatcgcaatg ggtggattgg gaagcgatgc
    10681 tgcaattgaa gcagcagatg tagtcatcat gaatgatcaa ccatcgaaga ttgcagaagc
    10741 aatccattta gcaaagaaaa cattgaaaat cgtcaaacag aacattgtct ttgctattgg
    10801 gataaaaatt ttggtacttg ccttaggtgc ttttggtttt gcatcaatgg gagatgcagt
    10861 atttgcagat gttggggtga cagtattagc tgttttgaat gccatgcgaa gcttgcatgt
    10921 aaaaaataaa cgttgatcaa tgaagaggac gaatgaacgt cctctttttt ttatatcctt
    10981 ttcttaatga aaaatgtaaa gaaaatagat aggattataa aataactaat gtttttaatt
    11041 ttgcagaaaa ttcaaaatag cttgaaattc aataaggtaa atgaaataaa agaaaataac
    11101 ttattttttt gatggaaaaa atatgaaaaa acgatgtgta ttaaataaaa gaatacacac
    11161 ataaaataac actgtcttgt aagtttgtta aaaattgaat atgattacat ctggataaca
    11221 aatttttatc ataaaggaga gaacgaatga acaacaaaca attacgctgg tttactgttg
    11281 cgttaattgc atttaacatg gtttggggca tggggaatgt agttaataac tatgctcagc
    11341 aaggagtatc agttgtcacc tcttggctat tgattttggc catttatttt attccatacg
    11401 cattgatcgt tggacaatta gggtcagcct tcaaggatag taaaggaggc gtcagttcat
    11461 gggtcgaaaa tacgacatct aataaacgac tggcatacta tgccgcttgg acttactggg
    11521 tcgtccatat tccttatttg gcacaaaagc ctcaagcaat cctgattgct ggcggttggg
    11581 cagtccaagg aaatggaaat atcgtaaata cgatgtcagt acaaatggta gcagttattt
    11641 cacttattat atttcttgcc tttttatatt tatcaacaaa aggactttct actttgaaag
    11701 tgattggcgg actggccgga acagcgatgt tcgtcatgtc gatcttattt attcttttag
    11761 ctgtaacggc accgttcatc aatccaacga tggaatttgc cacaccacat atgaatcaag
    11821 tgaaaacata tattccaaca tttgatttca gttatttcac aaccgtttcg atgctagtat
    11881 ttgcagttgg aggagcggaa aaaatatccc cttatgtcaa ctctacaaga aatcctgcaa
    11941 aggaatttcc taaagggatg atcttcttag cagcaatggt agggatttgt gctgtattag
    12001 gctcagtcgc aatgggtatg ctgtttgcta gcgataatat tcctaaagac ttgatggcaa
    12061 atggggcata cagtgctttt caaattttag gtaattacta tggtatcggt aactcattga
    12121 tgatcattta cgcattgaca aacatgattg gacaaatctc cgcattagcc ttttcaattg
    12181 atgcaccact aaaaatcttg ttagcagatg cggatccaga atttgtacca aactggctac
    12241 gtaaacgtaa tcgtaaaggt acattggtga atggttatct tctgacaggt atactagtag
    12301 gaatcattat tttgttgccg atctttggta tcaaagatat gaatgaatta gtaaaatggt
    12361 tgacgaactt gaactcagtt gtcatgccaa tgcgttacct atgggtgttc ttggcatata
    12421 tgatgttgaa taaagcttat aagaaattca attctgaata taaatttgtt aaaaatccaa
    12481 aaatcggttt tatctttggt gcttggtgct ttgccttcac tgcgtttgca tgtatcctag
    12541 gaatggtgcc aaaagtagat tatactgctg atcctaaagc atggtggttc caattattca
    12601 cgaatatcat cacaccaatt gtcttgatct tattaggtat gatcttgcca gcaattgctc
    12661 gtcgagacaa aaacaaagaa atcactgaac cagaaacagt ggttcagcct taaaatagaa
    12721 atacttgtta caagaggttg tgacagaagt ggtcagcttc aagaaataag aaggaattta
    12781 cgaaaattgc ttctcaaatt tttgtgaagt ttcggcttgt ttttcgcaga agctacttct
    12841 ggaacaccgt gaatcagagg ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc
    12901 aaacaaaaat agcccctcat atttttcgtt ttgctgggct tattaccgca gatgcaagct
    12961 tttgaacacc gtttaagaaa gaggtagtga gcctgccgtt taactccgag tcacaaggag
    13021 caatttcaaa aaacaacttc tcatgtttgt tgactattgt gccttgtgac cgaggtgttg
    13081 gcaggagaac accgtttaag gaagaggttg taaaatcagc gatttgacct gagtattaga
    13141 ggaacaaacg aaaaaatagc tcctcatatt ttgccgtttt ttgagttaat gctgaaggtc
    13201 agctgattga acaccattta ttcgaaacaa gggactttga cacgactttt gtcacagtcc
    13261 cttgtttttt tgcggcgtta taagtggtat gatcgaacca aattccaaag agaagtgagg
    13321 gagaagaatg aagatcatcg tgattggaca aagtgggtcg ggaaaatcga ccctcgcaag
    13381 gaagatcaaa gaaatcaccg actttccgct actgccgcta gaccttttat ggcatacaac
    13441 agactacagt attcaggcaa aaaagtggtt tttgcaagaa cagcaatcgt ttatggtatc
    13501 taatccgtca tggattgttg aaggaaatta tacttctaca ttagaggaaa ggattaaaga
    13561 agcagataag atcatttggc ttaaagtgcc gcgttatctc gccatctacc gagtagtttg
    13621 gcgttctcta aaaagaaaga taaacaaaaa atctcggcca gatatgcctg aatcattttc
    13681 agagaaacta aacagggaat acttagaatt tttatctttt atctggcatt ttgaagaaaa
    13741 caatgaaccg aaaatacagc agctgatcca agtagctaat gcaagaaata aactgatcat
    13801 ccttaaaaca agacgagaga aacaagaatt tttaactaaa ttgaaaatag agagcaaaaa
    13861 taattgacag tttttgttta caagcgtaat ctgtattcat aagctaatga ttacatttgt
    13921 aaacgaaagg tgtgaaataa atggaaaaag tcaaaacgcc agtaaagatc agtgattcag
    13981 agtgggagat catgcgtgtt atttggacac ttggacagac gacagcccaa gaaatcacgc
    14041 agatcttagc tgattcgatg gattggaaac cagcaacgat caaaactttg ctgggacgtt
    14101 tggtaaaaaa agaagtgatc tggacagaac aagaaggaaa aaaattcatt tatcatccag
    14161 ctgtctcgga gatggaaaca gttcgcagtg cgacggaaaa tcttttttcc catatctgtg
    14221 caaaaaggat tggagagacg attgcggatc tagtagaaga agccactttg actcaagaag
    14281 atatcaatga gattttgaaa caactggaac aaaagcaacc agtagatacg atcgaatgta
    14341 actgtatccc aggtcaatgt gaatgtaaac aacatcaata ggaggaagaa aaaatgaaac
    14401 aacaattttc aatcgaaggt atgagctgca atcattgtgc agcaagagta gaagaaacag
    14461 taagcgcact tgacggcgtg caaaaagtga aagtaaattt gaaaaaagca aacggtacgg
    14521 tcaagtttga tgaaacaaaa gttcaatccg aaaagatttg tcaagcaatc aatggattgg
    14581 gttataaagc agaggtgatt tgatggcaac agcagaaacc aaaatggata cgttcgtcat
    14641 tacaggtatg acttgtgcaa attgttctgc taggatcgaa aaagagctga acggacaacc
    14701 tggtgtggtc aatgccacag tcaacttggc cactgaaaaa gcaagtgtca aatatgaagg
    14761 gacgaccact gaaaaattaa tccaaagcgt agaaaacatc ggttatggtg caattttgta
    14821 cgatgaagcc cacaaacaaa aaattgcaga agaaaagcaa gcgtatttga aaaaaatgct
    14881 attcgatctt atattgagta cggttttgac tttgccgttg atgttgtcaa tgattgctat
    14941 gatgttagga agccatgcgg cgattgttca cttttttcat tttccaatcg tccagttagt
    15001 gctgtctgct cctgtccaat tttatgtcgg tgctcgtttt tataaaggtg cgtaccatgc
    15061 aatcaagacg aaagcaccaa atatggatgt attggtagca attggaacat cggctgcctt
    15121 tgcattgagc atttacaacg gatttttccg tggacacccc caagatcttt attttgaaag
    15181 cagcagtatg atcatcacgc tgattttgct cggcaaatat ttggaacata cagcaaaaac
    15241 gaaaacaggt aatgcaatca aacaattgat gtctcttcaa acaaaaaccg cccaagtgat
    15301 aagaaacggg aaagaagaaa cgttagcgat tgaagaagta gtcgttggtg atcaactagt
    15361 catccgtcct ggtgagcaga ttccagcaga tggtcgaatt atttcaggaa gcagtgcgat
    15421 agatgaaagt atgcttactg gtgaaaatct tcctgtagaa aagaatccgg atgacacgct
    15481 ttttggcggg acaatcaata cgaatggtct gctacacatg gaagtcacac aagtcggcaa
    15541 gcagacagta ttagcgcaaa tcattcaaat ggtggaagat gctcaaggga gcaaagcccc
    15601 aatccaaaaa atcgcagatc ggatctcagg gatttttgtt ccgatcgtat tagtcatcgc
    15661 gtttatcacg ctcatagcta caggtttgat cactggtgat tggcaactcg cattgatcca
    15721 tagtgtctct gtattagtca ttgcgtgtcc atgtgcatta ggtttagcga ccccaacagc
    15781 tattatggta ggaacgggtg ttggtgcacg aaatggaatt ttaattaaag gcggagaagc
    15841 attagaagca gctgctcact tagacagcat tgttttggat aaaactggaa cgattacaga
    15901 aggaaagccc aaagttacag atctagtcgg ttcaaaagaa gtcctatcta ttttttatac
    15961 tttagaacaa gcttctgaac atccactagg taaagcaatc gtggaatacg gaaaactgca
    16021 agaagcagca acatacgata tgattgattt tacagcccac ccaggtgctg ggatcagcgg
    16081 tacgattaat ggagtacgct attttgcggg tacacgtaaa cgattaattg aattgaacct
    16141 atcatttgat gaataccaag aacacgcgtt agaattagaa cagcagggaa aaacagtcat
    16201 gtttttagct gatgaaaagc aagtgatcgg gtggattgcc gtggctgatc aaatcaaact
    16261 agaagccaaa caagcaatca agcagctcca gaataaagga ttagatgttt ttatgctgac
    16321 aggagacaac aaactggcag ccgaaacgat tggtaaacaa gttggtattg atccaaagca
    16381 tatctttgct gaagtacttc cagaggataa agcagcctac gtagaaaaac ttcagaaaga
    16441 tggcaaaaaa gtcggtatgg caggcgatgg aatcaatgat gcaccggcct tagcattagc
    16501 tgatgtcggt atggcaatgg gaagtggaac ggacattgcg atggaaacag ccgatgtgac
    16561 gctgatgaat agcagtttgg catccattgc acaaacaatc gagttgtcta ggttgacatt
    16621 gagaaaaatc aaacaaaatc ttttctgggc ttttgtctat aatacgattg gtattccttt
    16681 tgccgcacta ggctttttga atccaatcat tgcaggagga gcgatggcgt ttagttccgt
    16741 cagtgtattg ttgaactccc tgagcttaaa tcgacacatg aaaaagtaag agaagggatg
    16801 gagtaaaaat gaatgggaac gatatggaga aaaaacatga gcataaaaaa gaagtagtaa
    16861 acaaagaaag tacagaatct catgaaaaac agatggagat gaaacatgac catagtcaga
    16921 tggatcattc catgcacatg ggacataacc atggagatat agcaaacagc aaacaaatgg
    16981 accattcgat gcacatggat cacgaacacg gcggcatgga tcattccatg cacatgggga
    17041 atttcaaaca aaaattttgg ctatcgctta tcctagctat cccaatcatt cttttttcac
    17101 caatgatggg aatggaattt ccatttcaag taacgtttcc tggttctgat tggctcgtat
    17161 tgatcttagc aactatacta tttatctatg gcggtcagcc atttttaagt ggagctaaga
    17221 tggaattgaa acaaaaaagt cctgctatga tgacactgat cgcgatgggg attacagttg
    17281 catatattta tagtgtctat tcgtttatcg caaatctgct caatccacat acacacgtca
    17341 tggatttctt ctgggaattg gctactttga tcgttattat gctactaggt cactggattg
    17401 aaatgaatgc tgtgtcgaat gccagcaatg ctttacaaaa actagcagaa ttactgccag
    17461 aatcagtgaa acgcttgacg aaagatggaa aagaagagac agtttcattg aaagaagtaa
    17521 acgaaggtga tcgtttgatc gtccggtctg gtgataaaat gccaacagat ggtgtaatct
    17581 tgaaaggtga aacaattgtt gacgaatcag ctgtgactgg cgaatcaaga ggaatcaaaa
    17641 aacaagccaa tgacaaagtg attggcggtt ctatcaatgg ggatggaacg atcgaaatcg
    17701 aagtaactgg aactggtgaa aatggttatc tagcgaaggt tatggaaatg gtgcgaaaag
    17761 cacaaggaga aaaatccaag ctagagtcat tatctgacaa agtggcaaaa tggctgtttt
    17821 atgtcgcatt aattgtgggt atcctggcat tcatcgcctg gttgttcttg acagatcttc
    17881 ctaatgcatt agaacgtatg gtaacagtct ttatcatcgc ctgtcctcat gctctaggtt
    17941 tagctatccc attagttgtt gctcgctcca catcaatagc agctaaaaac ggattacttt
    18001 tgaaaaaccg caatgcactg gagcaagcca atgatctaga tgtgatcatg ctggacaaaa
    18061 caggaacact aacagaagga aaatttactg taacgggtgt cgaagtactt gatgatgcgt
    18121 tcaataaaaa tgaaatcctt caatatctag gagccttgga agcgaatgcc aatcatccat
    18181 tggctgttgg cattatgaat tatttgaaag aacatgaaat caagccttat caagctgaaa
    18241 atctaaaaaa tctttcagga gtcgggctag aggcaacagt caaaaaacaa caagtgaaaa
    18301 tagttaatga aaaagaagtt gagcgtctcg gattaaacgt agaacaagca ttattgaaac
    18361 cttaccaaga acaaggaaat accatcagct tcctgatttt agaaaatcat ctagctgcaa
    18421 tcgttgcttt aggtgacgta gtaaaaacag aagcaaaaga atttatccga acattgaaag
    18481 aaagaaaaat cactcctgtc atgcttactg gtgacaataa aaacgctgcc caagcagtag
    18541 cagattattt agggatcgaa gaatattatg gcggtttatt accagatgat aaagaagctg
    18601 ttgtccagaa ataccttgac caagggaaaa aagtaatcat ggtgggtgat gggatcaatg
    18661 atgcgccaag tttagcccgt gcttcaatcg ggatggcaat cggtgcaggg acagatatcg
    18721 caatcgattc tgcggatgtc gtattgacaa acagcgatcc aaaagatatt ttgcattttc
    18781 ttgatctagc caagcaaacg cgaaagaaaa tgatccagaa cctctggtgg ggggcaggtt
    18841 acaatattct tgcaattccg ctagcagccg gaattcttgc gccaattggt atcatattaa
    18901 gtccagcagt tggtgctgtc ttgatgtcgt taagtacggt agttgtagct ctaaatgctt
    18961 tgacattgaa aatcaaataa taatgaaaaa aggggctctt tgtcaataag gactgatggg
    19021 ttgtacaaaa tcaaatctgg gtcagaatga acctcattct ggctcagatt ttttgttatc
    19081 ttactttgat taattgattg atcaaaaaga ttctaattct catgttctca aatgatttaa
    19141 atccgtagga tactc
//
LOCUS       DAXLPQ010000050        18919 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.050, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000050 DAXLPQ010000000
VERSION     DAXLPQ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.050"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(46..1365)
                     /locus_tag="ACF3UO_002096"
     CDS             complement(46..1365)
                     /locus_tag="ACF3UO_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3658068.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1362..2015)
                     /locus_tag="ACF3UO_002097"
     CDS             complement(1362..2015)
                     /locus_tag="ACF3UO_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3658069.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2303..2823
                     /locus_tag="ACF3UO_002098"
                     /pseudo
     CDS             2303..2823
                     /locus_tag="ACF3UO_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2821..3540)
                     /locus_tag="ACF3UO_002099"
                     /pseudo
     CDS             complement(2821..3540)
                     /locus_tag="ACF3UO_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(3565..3750)
                     /locus_tag="ACF3UO_002100"
     CDS             complement(3565..3750)
                     /locus_tag="ACF3UO_002100"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFD3658070.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3977..5250
                     /locus_tag="ACF3UO_002101"
                     /pseudo
     CDS             3977..5250
                     /locus_tag="ACF3UO_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5357..6388)
                     /locus_tag="ACF3UO_002102"
     CDS             complement(5357..6388)
                     /locus_tag="ACF3UO_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658071.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6395..7225)
                     /locus_tag="ACF3UO_002103"
     CDS             complement(6395..7225)
                     /locus_tag="ACF3UO_002103"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3658072.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7222..8037)
                     /locus_tag="ACF3UO_002104"
     CDS             complement(7222..8037)
                     /locus_tag="ACF3UO_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3658073.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8034..8858)
                     /locus_tag="ACF3UO_002105"
     CDS             complement(8034..8858)
                     /locus_tag="ACF3UO_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFD3658074.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8848..9948)
                     /locus_tag="ACF3UO_002106"
     CDS             complement(8848..9948)
                     /locus_tag="ACF3UO_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3658075.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10126..10911
                     /locus_tag="ACF3UO_002107"
     CDS             10126..10911
                     /locus_tag="ACF3UO_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3658076.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10944..11327
                     /locus_tag="ACF3UO_002108"
     CDS             10944..11327
                     /locus_tag="ACF3UO_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFD3658077.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11403..11534
                     /locus_tag="ACF3UO_002109"
     CDS             11403..11534
                     /locus_tag="ACF3UO_002109"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3658078.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11503..11739
                     /locus_tag="ACF3UO_002110"
     CDS             11503..11739
                     /locus_tag="ACF3UO_002110"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3658079.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            11751..11837
                     /locus_tag="ACF3UO_002111"
                     /pseudo
     CDS             11751..11837
                     /locus_tag="ACF3UO_002111"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(11817..12788)
                     /locus_tag="ACF3UO_002112"
     CDS             complement(11817..12788)
                     /locus_tag="ACF3UO_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFD3658080.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            13422..14882
                     /locus_tag="ACF3UO_002113"
                     /pseudo
     CDS             13422..14882
                     /locus_tag="ACF3UO_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(14805..15218)
                     /locus_tag="ACF3UO_002114"
     CDS             complement(14805..15218)
                     /locus_tag="ACF3UO_002114"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658081.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIADCRQKLFQTRNSSLEQLFIYFVSNF"
     gene            complement(15348..16724)
                     /locus_tag="ACF3UO_002115"
     CDS             complement(15348..16724)
                     /locus_tag="ACF3UO_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3658082.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(16724..17380)
                     /locus_tag="ACF3UO_002116"
     CDS             complement(16724..17380)
                     /locus_tag="ACF3UO_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658083.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(17390..18667)
                     /locus_tag="ACF3UO_002117"
     CDS             complement(17390..18667)
                     /locus_tag="ACF3UO_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3658084.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(18686..18847)
                     /locus_tag="ACF3UO_002118"
     CDS             complement(18686..18847)
                     /locus_tag="ACF3UO_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFD3658085.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
BASE COUNT         5835 a         3899 c         3060 g         6125 t
ORIGIN      
        1 aataagtctc tatttttcaa taactattgc aaaattatat cttaattaag aaaatatttt
       61 tattttaaag ataaaaaatt cttcatcctg caatacttta tattctatat tgtaattatt
      121 cagaatatta cttacaatat ataaacctaa tccattacta ttttccttat ttaaatcaaa
      181 tttaacatca aatattttat ccatattcga aattttattg ttaccgtatg aattctctat
      241 atataaccaa tcattaacta tcccaatatt aattacccca tttacatcag tatattttac
      301 cgcattacta atcaaattag atagaataat ctttaaagct gtttttccta tataaacatt
      361 ctcgtctaat atataattat tgacagttat tttcttttga tttgctaata tttcatactt
      421 ttttaatatg tcttctaatg tatcatttat tttcaaatat tcttcatcat tattcaaatt
      481 ttctatagaa tgaactgata atatttgaga aatatttttt gttaaactat caacgatttc
      541 aatacattca ttaatataaa tatctctttc tttatatttt ccaatattgt atttcatgtt
      601 ttccagtatt attttaagac tagcaagagg ggttttaagt tcatgggatg cacctttaaa
      661 aaagtcatat tttaactttt ctaattttaa aatttcttta tttttaaatt ccaaatcgtc
      721 aattgttctt aataaagtag aatacaaatc attaatttgt tgttttaatt ctccaacttc
      781 atcattagag ctaactttta aactcatttt tttatcaagt ttcatcattt tatcagtaac
      841 aatttttatt tcttgtatat tattttttat tgattttgca taaattaaag aaataatagc
      901 agaaaataaa attgatatta ataaagaata tggtaaaaat ttaaggctta aatctttcgc
      961 atctttttgc atatcagctg tagaaacaaa ttgtagattt gtttttttac catcattaag
     1021 ctttatttct ctttcttcaa ttatcaaaga attactatca ctttctaaat taacatttat
     1081 attatctttg atttgtattt cattcttatt atttttttct tttatgaata cttttatttc
     1141 actactcttg gaataaaact ccaaagtttg ttctatatat tttatttctt ttccattcat
     1201 attactagaa atttcatttg ccatattatg aatcttttct tttctcgtct ccaaatatgt
     1261 tttaggaaag ataaaaaaaa ttaatgaatg aactaatata attattattc caagaacaga
     1321 aaatatttgt atgaacattt ttggaaatat ctttaatttt ttcattttct ctccaattta
     1381 tatcctacat ttcttatagt agttatacag tctaattgta atttttttct aagttctttt
     1441 atatatacat ctattactcg atcataagga gtttcttcgc tatctttcca tacataatca
     1501 ataatttgca ttcttgttaa cacttgtcca ttattatcca ataaacattt taatacttct
     1561 agttcttttg catttacatc tatttcttca ccatttattt tagctgtata gctattaaaa
     1621 ttaaccgata gatccttata ttcaaacttc tctaaatgtc cataattctt cttaattaaa
     1681 gaatctattc tagcttttaa gaccggcaat gaaaatggct tttctacata tccgtctact
     1741 aaattagtaa atgcatcaat tttatattct tcatcactaa atgcagtcaa gattagaatt
     1801 ggtaaattgc ttttctttct aatttctttc aacacttcta aaccatttat aaaaggtatc
     1861 tgaatgtcta agataaccaa atttatatcg ctattaaatt ttgacaaggc ttctcttcca
     1921 tctttagctt gaataacagt atatccaaat tctgaaagat attcacttat tccctctctt
     1981 atcatattat catcttcaac agttaatatt ttcatatata cctccactta agcctataca
     2041 ctagatatta tacagcatat tatggctcta taatatctag tgttggtgac gccttctgtt
     2101 gccaatactt tttctttttt ttaataaatg caaacagaca ccttgaaatc ctttagaaaa
     2161 aaggcttcta taatattttg tgttgttgga aaatcgaagg cgattttcta ctaacacttt
     2221 ttcttcgttt caactcaaaa agagactcac ttttggtaaa atttagtcga ccaaaacatc
     2281 accctaccaa aggagtcgct ctatggataa tcatactaga aaattactcg gattaacaga
     2341 taaacattta ttttttgatg aagaatggct gattgaaaaa gaatataaag gcgttcaagc
     2401 gcagtttatt aaagggagat tggatgactc accttcccat tgtgaacact gtggatcgat
     2461 tcgtattatc cgcaacggtt cctatacgac acgtactcag atgttgaaag tcaaagaaaa
     2521 gttgactatt ttagaattaa aacgtacccg ttttctatgc tatgattgtg ggcagacctt
     2581 ttctgcgaaa acggacttag ttgatgaaca tcatcaacta acaaaggaac tgaagcaggc
     2641 gattctcata gaactgtacg aaaatcaatc acgtaatctg aaaatcagaa gaagtaccgt
     2701 cggctcaagc gatattggaa actcttactc aaagattcca cgacattgga gccgctcaaa
     2761 cggcattatc atcgactgtt taaacgacca attagtcaaa cagaaatcgt cgatgaaccg
     2821 ttgtgcacaa tggtgtcctg aacgtacagc gacaccttcc atatccagag cagtcgccac
     2881 atcacgggga tggatgccat ccaaattaaa agcaaccacg ccagtatgat gttcaggatc
     2941 ttgcggtccg taaatggtga taccgccgat cgcttgtaat ttaggtaaaa cgtaggcaac
     3001 cagttcttgc tcataacgat gaatattctc cataccaatc tcattcaagt aatcgattgc
     3061 tcctgcaatg ttcggagtac cagcttcaaa tttccatggc agctctttcc atgaactatc
     3121 gtaaagattg acaaaatcta tcatttcacc gccgaattcg actggctcca tttgttctaa
     3181 caattgacgt ttgccatata atacaccgat tcctgtcggc ccgcacattt tatgcccgct
     3241 aaaggcgaaa aaatctgcat ccaacgcttg tacatcaact gtcatatgcg gtgctgcttg
     3301 ggcaccgact ggactatcct caactacaac agcctgttca accctcagcc gtttcaagca
     3361 caacaaataa ccttctggat ctggtttgcc gacctgaaga tcatcgatcg tcacaaagga
     3421 atcaattttt tccttaatca tcggatgtgc ttcaaaaaaa tagtctagct cccgcagttc
     3481 agaattgaga ctactccgat tttccagtgc tgctgatccg ctgctcaaaa tgttcagcat
     3541 ccactggtct cccaaccgct tgacttatcc cttcataaaa ggacagttct gctgccgtcc
     3601 caacaccttg ttgatagtct gcaaaaggaa ttttatagcc gaactgctcc agtaaatagg
     3661 cttcagtaaa tagtgatgaa tactctcgta aaacatccat tcactgtcaa tcatcgtccc
     3721 atcaaaatca aaaataagtg ctttggtcat cttctttccc ccttacccaa aacaagcaaa
     3781 agctgtgtcc tgctctctct acagtatcag cataaaaact gccgtctgaa aagtcaaagg
     3841 tgaaagaaat gtggcgctat aatttctagg actgatagta aatcattcta tcagtccttt
     3901 tgagcataaa aaaacaaaac atacagaagc tccgttagaa ttgaatcacc acaacacaat
     3961 caaaggagcg ttctgtatgc ctgatcttca tcttatcaaa ctattactag gaatcaaaga
     4021 tggaaacatt caaatcactc atgtcgagaa gaaaaaaata cattcaatca acagtatcgt
     4081 tgtttctgcc acgctcatta aaacgattca gccctgtcct cagtgtaaac aggtgaatca
     4141 acatgggctg atcgttaaga acggaaagaa aaaatcgctg gtccttctca ataagtgtgc
     4201 gaatcaacgg acttatcttg ctttggcaaa gcaacggtac ctctgtcgtg gctgtcacac
     4261 ctattttacg gcgaatacct acattgttga aaaaaactgt tttatcgcca aacaagtaca
     4321 ttataaaata ttggaggaat tgactgaaaa acaagcaatg acgacgattt ctaaacattg
     4381 cggcgtttct tggtcaaccg tttcgcgaac actcgcttct ctgctcccca tgacaaacgt
     4441 gaaaataaat tggttgcctc gctgttcatt ggtagatgaa tttcgttcat tgaaaaatca
     4501 agtcggtccc tattcttttt cttgtatgga tggcgatact gggaaattac tggatattct
     4561 tccttcacgt aagaagaaag atctcatttc ttattttatg caatttgaac gacgtgcacg
     4621 tttaaacgta aaaatactcg taacagatat gaacgcctct tatgctttgc tgataaaaga
     4681 gtgctttcct catgccaaac tcgttgtgga tcgctttcac atcgtcaagc acctcattcg
     4741 cagttttaag gatatttgac tatgagtcat gaaaagcttc gaccgaaacg atccaataca
     4801 agccaaacac tatcgacaag tgaaggcttt atctcgactt ctgatcaaac gacaggacac
     4861 gcttgtttat gataaatgga caaaatggcg taattttggt tgggcctatt taaccgaaag
     4921 tgaagtcgta gaacgtctac tttctacttc tgatgaacta cgaatagctt atgcttacta
     4981 tcaagaaatt cttcaagctt tttatgacaa agaagcggac atcttctttc agcttgtaaa
     5041 aacaatgccc aagtcggttc caagagaact gcatcatata aaaaaagcgt ttataaacta
     5101 tgaatccggc attcgtttag ccttagagtt gccttactca aatggcaaaa tagaaaatct
     5161 gcatacccac atcaaagcat tgaaacgaat agcttacggg ttaggatgag aaccagaatt
     5221 ttcttaatca atcatctgat cacttattaa acataaaaaa acatctaaag cagaaaatca
     5281 attctacctt agatgttctt atatcactct atcagtccta tttgacaaag agccagaaat
     5341 gtttgccgac tatacactag ctttgttgtg caaaatgctg agtatcaatt tccacaggga
     5401 ttgctagaat atctttcagc tgaatgtata aggcatcgct aattttctct tcccgatcgt
     5461 tcaaccgatc cactaaaatt tctttgccct ccagcgtttg aaaaacatac cgttgaatgt
     5521 tgcctaaaat aaatgattcc ttccatagaa ccggaatctt aaccccctga ggaaccggtt
     5581 caaattgaat cagctccggt cttaaataat aaatgcagcg attgccctta gcggaaaact
     5641 cgtgggtata ctgattcagc tcataccatt cgaaacgatt atagttgccg ataaattccg
     5701 caacaaatcg gctctgagga ttctgataca attccttcga ggtggaaacc tgagccaccc
     5761 gcccagcttc catcacaaaa atccgatcac tgattcgcat cgcctcttct tggtcatgag
     5821 tcacaaaaat catcgtcatc cctagcgatt gctggatagc gcgcaaatcc cgctgcagct
     5881 gttttctaat tcgggcatcc aaagcactta atggctcatc cagcagcagg actttcggtt
     5941 cagtgaccaa tgagcgagcc agtgccaccc gttgtcgttg accgccagaa agaaactgga
     6001 catttttatc tgcctgctcc gtcatatcca ccaatgatag catctcaaaa accttttcct
     6061 gaatcacctc aggactcagc ttctttacct tcaaaccaaa ggctacattt tcaaaaacag
     6121 tcatagttgg aaacaatgca tactgttgaa aaacaaagcc gatattgcga tccttcgtag
     6181 gcttatcggc aatattctca ttgtccagca caatctcacc gctctttggt tgttccaatc
     6241 ccgtgataca gcgcagcaac gtagactttc cgcacccgct gggacctagt aaagtaacca
     6301 gctcaccctt ttcaatctga atttcatcaa tagctaaaat ctgtttttca tcaaaaaaca
     6361 gattgagatc atgtatttct aaaaacattt tccgtcacaa ctcctttaag ggcttctttt
     6421 tcgactgctt ctcttccctc gtctgcttaa gggacagctg ttgcttttgt cgataagtca
     6481 gcataaaggt agttaaagca attcccacca taaacagcaa atacaaaacc atcacagcgc
     6541 tagccaaatg gccgttttcg ttcatccgcc gcagcatata gatgcgtacc gtctgaaatc
     6601 gaccgccaat caacaggttc gtcagcatgt actccccaaa aaccgaagaa aaaatcatca
     6661 gagaaactag ggtcacaccg atacggatgt ttggaaacag cacctggata ataatcgtag
     6721 acatcggggc gcccaaggtt tctgctgcat ccactaattc cttcagatta attaagcgca
     6781 tctggttgtt aagactaaga tagacaatcg gcaacgccgt aataaacaat gcacctacca
     6841 acactacaaa cattgggata ccagtttcag catacgttcg aagcaaagcc gttaccaaaa
     6901 tcactcctgg taaagcatac ggcagcagga gcagcttttc cagccaacga ttcaaacgag
     6961 ggaaatacaa atgaatccaa ataatggtgg gaatcatcaa caacagaatc gtcaccaaga
     7021 ccacacctgc taataaaagt gagcgaccca ccgcagcaat aaattccctg tccgtcagca
     7081 gctgttggaa ccattgcaag gtaaaatcac taggtaaaag cgattttgac catttagtgg
     7141 agctggcata caaaatcgtt ccaataatcg gcagcaagta atacaggaca aagcagaaca
     7201 aaatcggttt tattaacttt ttcacgtctg caccaccttg cctttctttt gaataatcaa
     7261 cattgccgtt accagcagga cacctaaagc gactgccaac gcactgccta aattaggctt
     7321 ggcgaacaca tctcccgaca ctaaagccgc aattcgaatc gttaaaagat ttacattact
     7381 gctggtcagg gcatacgctg tttcataggt ccccatgcca ttagcaaata agatgacaaa
     7441 ggtgctggca atcgatggtc gcaaaaaagg caaagccacc ttgaaccaag catacgctga
     7501 tgaagcgccc agcaattgtg cggactccag ccattccttt ttcacttcct tcatgctggg
     7561 atacaaaaac aagaccccta acggaatttg gaaataggta tacgtgatgg tcaatcccca
     7621 ccaagaatac aaattgaagt ccgctagaaa tggcaaaatc attttcagca cacctacatt
     7681 ccccaacaaa ataataaaag agaatgccag cggaatccca gcaaaattag ctgccaaatt
     7741 ggaaacaaag gtgattttct cctgcaattt agtcgataga ttcattaagc ataaacataa
     7801 aataaacgtc ccgattaacc caatcacact ggagctgaca gcaatcagta cgctgttaac
     7861 aaaggcctgt gtgtaatatt tgttgctgaa aatatcactg taattggcca atgtccactg
     7921 gttagttaaa tcactgtgca agctgcacag aaccataaaa agcagcggca gcagtaaaaa
     7981 tgcacagaag ataaaggagg caggaaccag aaccaagcgt tttttcatct ctttcatccc
     8041 ctcatcaatt cttgaatgtc ctgcattttc tctgacggtg caattcctaa taaccagcaa
     8101 aacaatggag ccgccagcag ctgtggtaca gtttgttcct tcagcttttg gcgtttattt
     8161 gaaatcaaat aaaaaggaac ttcacgatgt gcagccaagc tgccgccatg cagtccgtgc
     8221 gcatccatcc cgtgatccgc agtcaccacg acttgataac ctttttgcag ccattcagga
     8281 aggtaaatag ccaataatct gtccgcctga ttaaccgctg ctgcatattc atgagaatcg
     8341 gcggtaaatt tgtgaccgac atcatcaata ttcatcgaat gtacgaccaa aaagtctggc
     8401 tgatactgat tcactaaata atgggcatcc gcaaataaat gcgaatcagg gtaagtgtcc
     8461 tcactataaa agatgccatg ctgaatcagt cgctcctcct gatgctggat gcgatcaacc
     8521 aaacgattat agggggcttg attgtacaac tcgctgtacc agtggtaagc ggcggctcct
     8581 gtttttccgc cagcttcctt aactaattca aacagcgacc actctttgga tcgctgagca
     8641 tggtaattac tatagatgcc attttcatag gctggaacgc cggtcatcag tacttcgtat
     8701 aacggacgtg aattgctggg cagctcactt tttaccttca ataagcttgc ttgctggtgc
     8761 tcaactaaat gattcatgaa cccaagctgg gcgacggctg tgtcgtagcg acagccgtct
     8821 agtataacta caatcagttt gtcaagtcta ctttgcatag gtcagtacct ccgcctgcca
     8881 aagctctgga agctctacag aggtcttgtt ccaagcttca ttgtcttcaa ctggcaccgc
     8941 cgcttcataa gcatcctccg gcagtaattt ttcagctact tctttaggca gctctacctt
     9001 gcgaataggt cgcgcatagc cctttgccaa attgatttgc ccttcatcag ataaaatata
     9061 ttcccgtgct agctttgccg cattgggatg aggggcattt ttattgatta aggttgtata
     9121 cccgctaatg atggagccgt ctgttggcac agttacctca aaacgctcgg agtcaatttg
     9181 gtcacgataa tttagtccat tgaagtccca aacaactgcc acatcgattt cacctttttc
     9241 aagatttgct acgctggcat caacggtgga caaacggcct ttttctgcca tttttttgta
     9301 gtaattcaga cctggctgaa tatccttttc gtcacctccg ttggcaatcg ccgcagccaa
     9361 tacagcaaat tgtgcttggt tggcaatcgt cacatccccc acgctaactt gatagtcacc
     9421 ctcttgcagc tccttccagc tagtcggtgc ttgcttcaca ttctctttat cggtgataaa
     9481 ggaaatggtt cccgtatagc ttaacaacca atccccatca tcatcctttg cccaatccgg
     9541 aatttcctcc caatagttgg tcttataagg taaggttaac tctttgcttt cagccaacgg
     9601 accgaagctg ataccgacat caccaatatc ggcggttcca ttttttcctt ctgattcaaa
     9661 cttagccaat tcttctgcac tggacatatc cgtatccacg tgacttaagc cgtattcttt
     9721 ttcaaggtcg ttccaagtgc ctacccaatt tgcccaagta tccggcattc ccaagctggc
     9781 aatctctcct tcttccttgg ctttttctat aatcgtatct aaagagtcgt ctgccgcagc
     9841 cgattgcttc gttgcttcac ctgagccgca gcctgtcagc aggatactta ctgttgctgc
     9901 acaaaataaa ccgatagtca tgttacgaat tttttcattc attttcattc attcttctcc
     9961 cctttcgata attccattct aacaaagctt tgtaatgaga gaatcagttt cttgaaaagg
    10021 tttcatgaac aatgtaaagg ttgtatatgg tttgtaaatt tcgacgaatt cccgttaacc
    10081 ttctaaagct tttgcggtat gatagtagaa aaaaggaggc tccctatgca gtattatgat
    10141 cagcatctcc acacgtattt ttcctttgat tcagaggaaa aatttgaaaa ctatttagcc
    10201 tatcagccgg agtttttcgt ttctacggat cactttgatt taaacaatcc atctaccgga
    10261 aaagatgaca ttccggatta tccagcctat ataaacaaac tggactcttt aaaagaaacc
    10321 tattccacca aatttctgcg aggtatcgag attggcgttg ttccaggaca agaagagcgg
    10381 atcgtggatt acctcgctca gcatccttat gatttaaagc tggtaagtat tcatcaaaat
    10441 ggccgctttg attatatgga cgatgtggtt ttaaccaaag atcccattca aactaccaag
    10501 gaatattttg atcagatgtt gcaggtcttg acggattttc cagaaggaga tattttgact
    10561 cactttgatt atggattacg ccgcttcacc ttcacagcgg aagaattcgc ggagcatttt
    10621 gaggctcagc tgctaacgat tttcaaaaag gttgttgaac gagaattggc gatggagtta
    10681 aatgccaaga gcttcttgaa atacggcaac gaagaccttt accgttatgc cgttcctttg
    10741 tatcaaagtg tcggcggaaa gctctttacc ttaggctcgg atgctcatgt tgccgaagat
    10801 tatcagctgg gctttaaaaa aatgagtcag ctgttggcag actgtcaggt agaaaagttg
    10861 ctagtcattc aaggaaaaga acgccgcctg acgccgctgc cgattttgtg attcctatat
    10921 aatagaagaa agtggtgaaa aaaatgagca acctgtggga ctacaatcaa gaggcaccca
    10981 tccattattt aattgcgcga cattgggatg cgttgaaaat tgaggcggtt tgccgatcct
    11041 tgttagcagc cgttccaaaa caacaactgg aaaatttttt ggtggctgac agcttgcagc
    11101 gggaaaaagt tcaggcttat tttgcagcct ttaaagatca gcctttggaa tatttgcatg
    11161 cgcagtttca tcttttttat caagtagccg ccccagatga ctacaacgat ttacgaggac
    11221 agctgcaatt gacctttcaa gcggatgaaa ccgcctatac cgttttattg ggaatggctc
    11281 gccttggtga tcaggcgaag gtcgagtggc ggattttcga tatttgatgg caggatcaag
    11341 gcgtttcagt tgcaaacctt cctctctttc aattagaaaa accgcagcag gaagaagttt
    11401 gtgtgctggt caccgatgct ggtgaaattc gtctccgctt atttcctgac caagctcccc
    11461 tggctgtagc caactggcgc tccctagctg agcaaggcgt ttatgacaac acacctttcg
    11521 gctcgtgtca ttaaggaatt tgttattcaa ggtggcgctt tggatggttc tggtgatgaa
    11581 gctgtttcca gctatgaggg ctttttcgct gatgaagtgc atcgcggact ttatcatttt
    11641 aatggcgcct tggccttagg ggaccacggc ccccacacca acggcaacca gttttttatt
    11701 gtgcaaaaca caaaggcgca ggctgacctg ctaatgtaaa gcaagcatac ttggagcttg
    11761 gaggactacc ggagctggat ggtcgttata ctgtttttgg acaggtatac caagggttag
    11821 aaatcgtagc agcgatcgca gctcagccga caaacagtga agatgtaccg attgagccag
    11881 tgttcattcg acaaattaac ttcgaaaaaa catcgtaaaa agacactcac tgacttcagc
    11941 aaaagctcta ttcttgagct ggctgcagct agtgagtgtc tttcatttat ccataagata
    12001 aagcttggat tcaataaata aataaatgtt ttggttaaag ctgtgaccag caaatgagga
    12061 accgtgcgag ccagttgatc tgccaatgca aacatttctt taggtgaagg cgctggcgtg
    12121 tctgccaacg gatactccag tcccaatgct tggtaaccgt gcataccata gcagtggtac
    12181 ggtagtaatt ctaacggtac gaaccgatca agatctgcca caaaacaagc aatcgtcagc
    12241 agctcggtca ggttcatatt gatacctgga accacaggaa ctcgaattcg cacttcgcag
    12301 ttaggatact caattaaaaa gcgacgaata ttcttcaaaa tttgttggtt atctaagccg
    12361 gtccattgtt tgtggagctt gctggtaaac atttttacat ccacaaacaa tgtatccaca
    12421 tagggagcta ccttttggat ttcattataa gcaccacaaa agctggtttc cagtacggta
    12481 ttgattccaa tgtatttcga tttttgcaaa atttctttag caaaatccgc ctgaaccagt
    12541 gcctcgcctc cgctaatggt cactccgcca tccgagtgaa agtaaaaaac agcatccttc
    12601 tcaatctcat ccattacctc ttcagcggtc atggtctggc caaatccttt ttcaatctgc
    12661 ttgctttgtg attcgggaat cgaacaccag gcacagcgta atgggcagcc ctttaaataa
    12721 acaacggtcc gtaaaccagc accatcatgt agagaaccct gttctattct taatactgtt
    12781 ccttccatat agatttttga attacacact agtttaaact aaaacacaca aggaaaaact
    12841 taccatttaa tcataaaatt agctcatata aatatactag gatgtaaaat agactggtca
    12901 aaatctggtc aaaaaagagg actaatacag gtagtcctct tttttgttat tttaatattc
    12961 taaatcattt tttattggtt tattccctta ttcgatgtag actcaaatca ctatatcact
    13021 agatatcaaa cggcgtcata cggaatcaaa aacatcaaat ttgacctgtt aaatggtcat
    13081 tgaataacat tcaaaatcaa taaaacggag tcagacacgg agtcaaaaac gctgagagta
    13141 aaaaatatat acagccttgt aggtaaagta ccacagggct gtatattttt tatttcagat
    13201 taccttaaat gattccattt actttttatc tcattttttc ctactagtta gtatcaaata
    13261 ctctcctatt ttctcaataa actatttttg gatacatggt atctgaaaca gctaaaacct
    13321 tgtcattaca gcaaaaaatc acgttatcca gactgtagac aaagtccatt ttatggatga
    13381 tgtctacagt cttttctttt ataatagatt tatgaaaacg aatgcaagga gtgatagcta
    13441 tgatgtctaa aaacaatacg aatggtagaa atcaatttgc gatgcttacg attgatgatc
    13501 tagttcctca agatcatctc gttcgaaaga ttgatgccgc gcttgatttt gaatttattt
    13561 atccaatcgt cgaagccact tactccgatt taggtcgccc aagtatcgat ccagtgattc
    13621 tgatcaaatt ggtgtttatt cagtatttat tcggtatccg ttccatgcga caaaccatta
    13681 aggaagtcga taccaatgtc gcttaccgct ggtttttagg ctactccttc gaggagaaaa
    13741 tccccccttt ctcaactttt ggaaagaatt atgttcgccg atttagagaa acgacggtgt
    13801 ttgaggatat ttttgcctat attttagaac aagcagttaa agcaggtttt gtaacagagg
    13861 ataatttgta tctggattct acccacatca aagctaacgc caataaacat aagtttacga
    13921 aagaaatgac ccatgatgaa gcgaaagcct atcaggatga attagaagat gagatcaatc
    13981 gtcaacgaat agaggctgga aaacgccctt ttactttgga cttagaaaag gaagtgaagc
    14041 tgaaagaaag aaaaataagt aaagctgatc cggaaagcgg ctactacgtc aaaggcgaac
    14101 gagaaaaaca atttgcttat tctgtccata cttcatgcga cgacaatgga tttattctta
    14161 gcacaatcat cactcctaga aatattcatg acagtcaagt cgcctttcag ctcgtcaaac
    14221 aatcgaagag actttttcct gaaatcaatt gtgttgtcgc tgatgctggg tataagacac
    14281 ctaagtttgt tcactttttg actcatttga accttcgacc ttgtttgcct tattcaaggc
    14341 ccaaagggaa aaaggagcta ttatcaaaaa atgagtttct ctatgacgag tattttgatt
    14401 gttatatttg tccgcaagat caaatgctcg ctttttcaac ggttactcga gaagggtacc
    14461 gagaatacaa atccaatcca aaagaatgtg tgaactgtcc tctgctaaac caatgtacca
    14521 taagtaaaaa tcatcaacga gtcatcacga gacatgtttg gggagatctg atggatgaag
    14581 tggaacatct tcgcctaaca gatctgaata aatcaattta caaaaaacgg aaacaaacga
    14641 ttgaacgaat atttgcggat gcaaaagaaa agcatgggat gcgttggacc aagtatcgag
    14701 gcttggaaaa agtcgcgacg catacgatgc tagtgtttgc tgcaatgaat ttaaagaaat
    14761 tagccacctg gctatggaaa ggcaaggagc ctttattttt ttgttcaaaa attcgaaacg
    14821 aagtagataa aaagctgttc caagctcgag ttacgagttt ggaacagctt ttgtctacag
    14881 tctgcgatgt cggagacatc tcgttttcta ttaggaatca actcaggttc aaaagaagcc
    14941 tcccggtctc tgggaacatc aatgtttact ttaccaaagc tcgttttaag cgtcttattg
    15001 ccataaccgt ttcgtcgatt gtcatgtttc tttggctctt tagaatgggc gtcataccct
    15061 aaatggttat tcaattctcc ttgaagcatt ttttcaaata agggaccaaa cacatctttt
    15121 aaaacatctt gcatatcctc tacagattcg ggttgataag tattcaaaat ggattcagct
    15181 aacttctcag catcaggatt tcttttcttt ctagccatcg tgtaatcacc tcttgatctt
    15241 attttagaaa aataaaaacc gtgaagcaac cacccgccta ggattgatgg ttacttacac
    15301 ggtttatatt acactctcat ttttggtgct aaaaagcacc gaaaatttta attattgtca
    15361 attaataatt cttttggatt ccttcttaat atattgaatg aagaaataat caatgataca
    15421 agaagtacta aactcataaa tataactaca taaatcatga atttaggtaa tacattgata
    15481 tctaaacttg ataatgtctt gttaaatcct tcagcttctg ccccaccacc taattggcta
    15541 gatgcagatt gtttagctat ttgtttagct atatcaccag taaccttatt caatatatta
    15601 ttcccaagct tgtcagctgt atattgagct aagaaatagg aaccaacgaa tgcggggatt
    15661 gatataaata ccatctcaat taggaattga ccaaaaattt ctaattttga tatacctaat
    15721 gatagtaata ctgctatttc tttctttcta gcattcatcc ataagaataa taataatgaa
    15781 actacaactc ctgcaaatat taatgagcca aaaaataatt tatttgaaat tgagtaaata
    15841 cctgatatag attgttgtaa tgcagggtaa tttgatgaac ttttaatcaa attatattct
    15901 ctccaattta tatctaattt cccaagatct tttattacac tatcaagatt cttatcacct
    15961 tttacaaaga atgttgcatc ttggtataca gctgtatctt cggtattacc ataaacttta
    16021 gcagctgtat gaatatcagt gattaatgta ttttcgtata gttcttgtgc tgcacttact
    16081 acaccgctat tatgcccatc gaatagacct ttaatttcta cttctactgt ttcatctgca
    16141 cctttctcat tatcagcatc aaataaatta gattttattt ttatcttatc tccaacttta
    16201 aggttatttt tttcagctaa atctttatgc attaagattt tatttttatc ttcattttct
    16261 aaatgctttc cttctactaa tttatatgct tctgatacaa attttgtttc ttttgttgag
    16321 tcgttaaccc cagttaacat aactgttctt ttaaaattct ttgctctttc aggtgattga
    16381 ttcgcaagag tctcttgagt ttcaataata tcataatcaa ctaaatctgc aacactgttt
    16441 attcttttta cataggagtc tatactatct gtttgagata tctttttaat atcttcacct
    16501 tttacatttc ccccacctct aggtgttcct ggatttactt gtctatttat ctccatagaa
    16561 aaactatttg ttatattagc aaatgtttct tttgaagctc tgtccgtagc atctttaata
    16621 gataaactaa tgagacttaa agttgacata gataaaataa ctaatatgat aattaatgat
    16681 tttaaacttt ttctagttac ataagcaaat gcatttttta tcattattca acctccaaat
    16741 tcattttatt tacttttttc aactttttac cacttagttc taaaatgata tccgcagaat
    16801 ctgctacttc cttactatgt gttacaacta ttacacattt atttctatct ttagctaatg
    16861 tctttaatat attaattatt tctccagcag taacactgtc tagattacca gtaggctcat
    16921 cagctagtat tattggagca tctgatacca atgctctagc aatagctact ctttgttgct
    16981 gtccaccaga taatttcata acatttcttt ttatttgttt tttatctaaa cctagttcaa
    17041 acaagatact ttcatctgct gatttattta ctaatctaat attttcaatt ggtgataaat
    17101 aatctattaa attatagttt tgaaatacta aagatatatt attttttcta tgattactat
    17161 atcctttatt ttgtatatct tcattcttaa acaatatttt tcctgtttga ggtttatcaa
    17221 gtccagcaag taaggaaaga agtgtagatt ttcctgttcc tgactttcct actatcgcat
    17281 aaaacttccc aagttcaaat ttttgattta ctcctgacaa aactttttct ttagaatttg
    17341 cataactata tgctacattc tttatttcta atatatccat tattttctcc taacttattt
    17401 ttgataagat ttctttaggc ttcttgatta acattaatga agaagcaaat acaactgata
    17461 aaacaataat acttattaat attaaataac tttgtccaag tgttgttata tttgacataa
    17521 aactactatt atttattaaa cttccaccgg aaatcattga atcctctgag ttaatgaatc
    17581 catctacaat tacttttagt aatacatttc ctaaaaataa ggaagatatt atacttggta
    17641 tcgatatgaa tattaactcg aatataaatt gcattataat ttgtatctta gatgttccaa
    17701 tagataagaa tatacctatt tcataaattc tttcccttaa ccatagaatc aagattaatg
    17761 aaagaacaac catcccacct aacataatag aataagtcat tacttttatt atatatttta
    17821 ttccactcac tgactctaaa gactcttcaa acgcattaga atctttttca acaaaatact
    17881 ttgactcatc aattttaagc tctttcaatt tgtttaaggc taagtctgta gattctgcac
    17941 taccagaata cattaaaatt ttatttgcaa tttcattatt ttctgaatta tttaatatct
    18001 cttggcttgt tgaataatct acaaacacca tattttcact aaaatcagaa gataatcctg
    18061 tatatgtttc ctgtttttta ccagaaaaga tccctataat tttaaattta tgacttttta
    18121 tttttccact tttttcaata tctagtaatt caagatcaac ttcatcacct aattttagat
    18181 tgttttgttt agcaaattct tcatgaacaa taattgaatt cttatcattt tcttctatat
    18241 ttttaccttc tttaattgta aatactccac tactaaataa aatatttctt ttagtattat
    18301 ttgtagcttc gagtgaaaca acattcttaa attcgtcaga taaatcttct ctatttattc
    18361 tttgttctcc gctaactact ttagcatctt ttagttttgc taatccatca tattgaatta
    18421 ttttttcttc aatttctttt aatttttcaa tatctttaaa ttgattaaca ttaaaatatt
    18481 taccatcttt ttttgttatt gatattgaag aattagaact ttcatataaa gccttttcta
    18541 tttcattgct tgatttcatt attgttaaac aagaatacaa gcaagaaaga actatagtta
    18601 atatgataaa aattattaaa gttctatttt tctttcttgt aatatatgct atagcatttt
    18661 ttatcacttt cctaactact cctctctatt ttcttactcc ataactaatt gcatccactg
    18721 gacaagcatt tttacatcgt ccacatctga tacactccag atgattgcaa ttctcaactg
    18781 aatctttatt catttggcaa acttttttac attttccaca attaatacac ttatccttat
    18841 cctgaatcgg ctacactaga ctagacagaa aaaataaggt gtgtagaata ataaaaaaca
    18901 cactggagga tttttcatg
//
LOCUS       DAXLPQ010000051        17766 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.051, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000051 DAXLPQ010000000
VERSION     DAXLPQ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.051"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(45..755)
                     /locus_tag="ACF3UO_002119"
     CDS             complement(45..755)
                     /locus_tag="ACF3UO_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFD3658086.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(773..1269)
                     /locus_tag="ACF3UO_002120"
                     /pseudo
     CDS             complement(773..1269)
                     /locus_tag="ACF3UO_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(1306..1758)
                     /locus_tag="ACF3UO_002121"
     CDS             complement(1306..1758)
                     /locus_tag="ACF3UO_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3658087.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWSFVKKGNKRIY"
     gene            complement(1893..2498)
                     /locus_tag="ACF3UO_002122"
     CDS             complement(1893..2498)
                     /locus_tag="ACF3UO_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFD3658088.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(2948..3568)
                     /locus_tag="ACF3UO_002123"
     CDS             complement(2948..3568)
                     /locus_tag="ACF3UO_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3658089.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(3570..4439)
                     /locus_tag="ACF3UO_002124"
     CDS             complement(3570..4439)
                     /locus_tag="ACF3UO_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFD3658090.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(4462..4869)
                     /locus_tag="ACF3UO_002125"
     CDS             complement(4462..4869)
                     /locus_tag="ACF3UO_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFD3658091.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(4888..6177)
                     /locus_tag="ACF3UO_002126"
     CDS             complement(4888..6177)
                     /locus_tag="ACF3UO_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3658092.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(6204..6506)
                     /locus_tag="ACF3UO_002127"
     CDS             complement(6204..6506)
                     /locus_tag="ACF3UO_002127"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3658093.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(6531..8624)
                     /locus_tag="ACF3UO_002128"
     CDS             complement(6531..8624)
                     /locus_tag="ACF3UO_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3658094.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(9113..9841)
                     /locus_tag="ACF3UO_002129"
     CDS             complement(9113..9841)
                     /locus_tag="ACF3UO_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFD3658095.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(9986..10699)
                     /locus_tag="ACF3UO_002130"
                     /pseudo
     CDS             complement(9986..10699)
                     /locus_tag="ACF3UO_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
     gene            complement(10700..12607)
                     /locus_tag="ACF3UO_002131"
                     /pseudo
     CDS             complement(10700..12607)
                     /locus_tag="ACF3UO_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
     gene            complement(12721..14053)
                     /locus_tag="ACF3UO_002132"
                     /pseudo
     CDS             complement(12721..14053)
                     /locus_tag="ACF3UO_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(14019..15497)
                     /locus_tag="ACF3UO_002133"
     CDS             complement(14019..15497)
                     /locus_tag="ACF3UO_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3658096.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="ACF3UO_002134"
     CDS             complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="ACF3UO_002134"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFD3658097.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
BASE COUNT         5054 a         3810 c         3016 g         5886 t
ORIGIN      
        1 aaaaaaaaac ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct
       61 gattcatctt tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt
      121 tccttcaacg cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca
      181 atgaccagca ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag
      241 ttgagacagc gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc
      301 ggagcatcgg aatctgcacc taaaggcagg aatgattcgt caccttgggc ttttcctaaa
      361 tgcagatttc ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag
      421 gaaatactat tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt
      481 gcacgtttca gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta
      541 aatgcctgac gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa
      601 tttcttgctt cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt
      661 gttacgtggt tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact
      721 tcccagaaat tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata
      781 attgcttgat gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc
      841 tgtatttgat aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa
      901 caccgagcca aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta
      961 aaaatgtacc gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta
     1021 aaaaatgatc agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg
     1081 caggctcttg atcgatactc actaggaaaa aatctgtttc tttatctttt agctcttctg
     1141 taagtttttc tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtaattatc
     1201 ttttccaaat gtatctgtaa atgtttcgat actaatttgt tgtagtaagt ctacatctga
     1261 aggcgtcatt tttcgaattt cgtatttatt cacggcttct tcctttcaat agatcctttt
     1321 attgcctttt ttgacaaaac tccaatcttc gctaacattc ttgcatactt tatttaaaag
     1381 atattccaat tgttttgctt cttcgtcaga aagaccattt aatgcgactg cattggagta
     1441 gttgttttct cgaatgatga aaggatagat ttctgctcct tttttagtcg gatagagttt
     1501 cttgattttt ttattttctt tatcttccaa acgttcgatc atcccattgg attctaattt
     1561 cttgattgct cgggcagtcg ttgtacgatc tactttgatc atttctgcta gtttttcttg
     1621 gatgattcca ggattttcgc aaatacgtac taaataaaga tactgtcctc ttgttaaatc
     1681 gacttctttg aattcgatat tgctaataga gtctagcgct cgggcaatca ttccgatgtc
     1741 tcgaaggatt tcagccattt catcccacct ttattttgtt tgtaagacta gtttacctct
     1801 ttttgttgca aatgcaacta tttttaataa aaaaatcaag ttctttttta ataactagta
     1861 aagtatattc ttttcttctt ttacgaaaaa gctcaatcac aatagatctg gtttttgttt
     1921 tctaaaataa gtaactgttt cttcgttgtt cgcttttctg atagctttgg caactcttct
     1981 atactaaaaa atcccatgtt ggaagtttca ttattctcaa taaacttggc ctcttcaccg
     2041 tggatcgcac aagcaaaaac aagtttataa tactgaaaaa gctgtggaat atctttttgt
     2101 ttattcgtat caaaaactgc tcgcaactga gtagtttcta ctgttaatcc tgtttcttca
     2161 tagacttctt tacgcacatt ttcttcagga gacaatccta tttcagcaaa tccaccagga
     2221 agtgaccatt ctttcgtccg tttatcttcg attagtagga ccttgccatc ttttttgata
     2281 taggcacgaa catctacttt tggtgttgga tgtccttctc caatcgttgt gagcgctttt
     2341 atttcttcga aagtttcttt tcctatttca ctgatcagtt ccaatgaaat cgtccggatc
     2401 tcctcaaaac gctctttatc aaatacatct tttccataat atagaccagc ttgagaaagt
     2461 gcgagtagtc ttttgtattg agccaacttc ttgttcattc tcttcccttc ttttttagca
     2521 aatgtatgac tatgtaatca agtatagaag actggtttaa ttacggcaaa taaatataat
     2581 gaaatctgca ataaataaaa gaatgttaaa aaactcgaga acaaaagaca ttcgacttct
     2641 ctggggctgt gaataaatgg cgttcaaaag cttgcatctg cggtaataag ccccatcaaa
     2701 cgaaaaatat gacgagctat tcttgtctgg ctgttcttat taattgaggc aggacagctt
     2761 tttcacaacc tccccactaa acggtgttct cctaccaact cctcggtcac aagtcacaat
     2821 attcatcaaa catgagaagc tgtttctttg aaattgctcc ttgtgactcg gagctgaacg
     2881 acaggctcac gacctctcgg taaacggtgt tcaaaagcca atttttcgat attaagccat
     2941 ttctttgtta cttattgtca ttgatttctt tttctaattt atccaatagt ggagtgtaat
     3001 ccacttgagt atagtctgtt acatcaaatt catatagtgt tcctaactgg aatttgtcat
     3061 attttcggtc ggcgatgatc tttttgaatg cttctttcgt aatatgattg gtccctttcg
     3121 ttcgatcttc caatacgtca ccatagtgat aatgatccat gatatagctc aaatgacgat
     3181 ctgattcacg atcacgtttg taccgacgtt gccataacac ttcaaagtct gctgttaggc
     3241 gaatcgtgat cacctgatat ccgtatctat ctgctaattc ttggagtcgt gctttttgct
     3301 tatcactaaa aggatactcg gacacaatca ctttctttcc tgcttccata tacaaatcaa
     3361 gtgctttgta atagaaagga taaactttcg tcctttcttg ttccgcccgt tcttccaaat
     3421 tgttaaaccc gatggattct gcatagtatt ccttgatttc atcgagcgtg atggcataca
     3481 tatctggaaa tcgttcccgt agtttattca taagatatgt ttttcctgta ccaggactac
     3541 cagccagaag aatgaaatac tttttcatct catttatttc ctaagttaat tggactttcc
     3601 aagttcataa acagtccaat cttatgcttg acaatttctt ttactgcttt atttgctgga
     3661 atcacattat ggcgaagaga cttgttgatt tctgtttcac taaaggtttc tttagctact
     3721 ttcgtccagt tgactaaaag ctccgttcca acattgaatt tgcggatccc gttattgatc
     3781 aattcaggat aatcttcttc tttcacacct gttcctccat ggataactag ggggacatca
     3841 actactgcat cgatttcttt cagcaaggga atgtttactt ctgtttttga tttgaattgt
     3901 ccatgattcg taccgatagc aatagctaat gcatccacgc ctgtagcttc tacaaatttc
     3961 actgcgtctt ccggtcttgt atataccttg tcattttcag cgacatggat tccttcttct
     4021 gtaccgccga ttgttccaag ttctccttct acggaaacac cgtgcgcatg ggcatattct
     4081 actactgctt ttgtcttcaa gatattttct ttgaaaggta gatgggaccc gtcatacatg
     4141 acagaagtat atccgctatc gattgcttct ttgatatcat caaagtctcg ggcgtggtct
     4201 aagtgtaaga ctgcatcaac catttcttct tctgcaatag ctgtcattac attgactaac
     4261 acatgcatgc cgatatattt agcggtatcg acacttgttt gaataatgat tggcgaaccc
     4321 atttcttttg ctgcgcctag catggcagga agcatttcta ggttatgcgt attaaaagct
     4381 ccaactgtaa aattcaactc ttctgctgtt tttgttactt ctttcaatgt tgtatacatc
     4441 ttttattgcc accttatctt tttatttgtt tcctttgatc gttacttgtt ttgcaatttg
     4501 tcgcatctca tccattttgc ccatgtagta atcgatccct tgatcatcac cagcacgagc
     4561 agcatctgca cgcttctggt tatagaggct catcagtttt ttatacccat ctccgatcgt
     4621 ctgtttattt tccaagctct tttctaaata ttggatggct tgatcgttct catgcaattc
     4681 agaaaattta agtccaactt gttcataaag ttccgctaat ttatgcctat cttgggtagt
     4741 ggaaatctct tgtttcaatt gtgtaatctc tgattgaatc ttttcggtcg cttctggcga
     4801 tagggctttt tcttcttttg ccagaacttt tttcggttct ttttcttttt tcttaaaaaa
     4861 tccaaacatc attttcccta ctttcaatta aaacgctttc aaaactgggc ttaagatcca
     4921 ggcatataag agtgctgcgg ctactgtatc tacatcggtt gctgtagcat tgatgaatcc
     4981 catcgaatta aagatcgtta ctagcaaagc gggcaataat gtaataaaga aaccatgagc
     5041 aataccgcca atgatcgctc ctcggcgtcc gccaactgcg ttgccaaata tccctgctgt
     5101 ccctccggca aagaaattgg ttagcatacc aggtaaaatc atcgctaagc cgaacatggg
     5161 caaagtaaac atggcaataa tcgtaccaat cgttgtcgta atgaaaccta aaatgacggc
     5221 atttgggcta taaggaaaga aaactggaca atctaaggca gggatcgcat caggaactaa
     5281 tttcatagct atccctcgaa atgccggcac gatttcacct aacagtagac gtacaccagc
     5341 tagcaatata tacacaccca ctacgaattg gatggcttgt aaaaaggcaa acatgatata
     5401 gttttgatct cctgataatt cagaagcgaa tggttcgcct gcaaataaaa cagtgatgat
     5461 atatagcggg accatcacga ccatgacaga caaataagta tcttgcagaa attcgaaatg
     5521 tgtcggcaac ttgatatctt cgatcgactt tttattttcg cctttctcac caaaaagctt
     5581 agcaacaccg gcttcaaata agtacccgat cgtacaaaaa tgacctaaag caatatcatt
     5641 tgatccagtg attttacgaa tgatcggttg cgctactgcc ggcatagcaa tggcgaaaca
     5701 agctccgata aaaccaccga ccaagatcaa tacgatccct cgcagaccgg caaaatagcc
     5761 aaagactgtc gtcatcgttg ccatccataa aattgcttga ccagttaaaa aaatgtactt
     5821 ccattttgtg aaacgagcca aaataatatt gaatacaaaa atggctaaga acgtcagtgc
     5881 aatatctcta cctaaaccca aatcattcat tgcttgatca ttgatagatt caatagaagg
     5941 gatgatccct tgcatatgaa atccttcagt aaagattttc ccgaaataag ttaaacttcc
     6001 aacgatgatg ctcgaaccgg cactcaatac ttgaaatcct aggagtgttt ttaacgtgcc
     6061 agagatgact tgtcctgctg atttcttctg cagtagtaga cccaacatag caatcaatgc
     6121 aatggtgatc gatgcctgag tcaaaatatt ttcgatgata aaattgataa cgctcatgtt
     6181 tttaccctct tttctttttg tatttagata actcccttat cttgcagaac tggggtgatt
     6241 ttttcttcaa tttcattttt tgaaacaata tttttcaaat agatcatcgc cgttttagga
     6301 tcaactgcga acttttcgaa ctgcgaacga aaattttctg ctgtgatgat cacatctggt
     6361 ttcatggaaa ctgcggaaga aatatcacaa tggtccagtt tggcttctac tcctaatttg
     6421 ttcaaaacat cctcagcaga catctgtgct gcaaaactac ttcctaaacc tgcgccgcat
     6481 acgaataaaa tgttcaattt gttcatcttt gttctccccc gtatcattta ttatttctca
     6541 actactgaaa aaagcagttg tttgaaatct tcgatatttg tgcattcaat caatcgatcc
     6601 aacttctctt cgttgttgat caattcaatt agttctttca tgatgttcag atgggagtag
     6661 gagtctactg ctgccaaaca aaaaataatc tttactggat ccatttcagg attaccgaaa
     6721 tcgattggtt gctcaatcgt agctacgctg actcctaatt tattgacccc atcttctggt
     6781 cgggcatggg ctagtgccat gtgtttgcca atcacgatat acggtccgta atcattcact
     6841 gcacgaatca tcgcttcgac atagcgctct tcgacaatgt tttctttaac caatggtcta
     6901 gcagctagtt caatcgattc ctcccaagta gtggcttttt ctttgatcat gatattgctg
     6961 tccgtcaaaa tatcttttaa cataggctgg atctcccttt tgttgatttc taaattgttt
     7021 gtttcgaata atttttctaa cttgccatag atgattcgat ctactcggcc accactttct
     7081 ttcatgacat ctattatttg agtgaataac tccgtcgatt catgactgtt aggctctaac
     7141 cgctgtagtt cttcatttct tttcaaaaag tcttctataa ccaagatatt cgtctcagtt
     7201 aaaatcggat cgacaactaa aagcggctta tttcgataat tcaattgaaa ggtgctgaaa
     7261 accagattga catccaattt atctactaat tcgatttctt ttgaacttaa aactgcagta
     7321 atctcgatct gaggaaactt ttctttcaga ttctctgcta acagatttcc agtagccatc
     7381 ccatggttac agacaacgac tgatttataa acataattca agtctcgctt gattacactg
     7441 gcgatcgtcg aaaagtggat gacaagaaaa gctatctcgt cctccagtat cttgccacca
     7501 attacttctt cgatcgtagg aacaaaatga gtgactgcgc ggtagattgg gaaataattt
     7561 gttcggatgt tttctttcaa tggattcatg acttggatat gattcttgat tcttacaatc
     7621 agtgcagcca tgtgcttata gagattttcg aataaggctt cttcctttag atggaaaggt
     7681 acgtgtgtct cgttctctac aaattggatc aattggatcg ttagtaattg agcttgtacc
     7741 cactcgattg aattggagat atctctagca ttgaacgtct caatagtgaa acgaagataa
     7801 tttctttcta cttgcgggac attgtccaat tgaaattcct cgatcatgtg gtcaataaat
     7861 gcagaaaagc tactgtcttt tatttctgta tttttccaat taatggcaga gataaattca
     7921 tgtttcctga ttcgctggat ccagatcaat gtaaaaagca ggatttgttt tttataaata
     7981 tcatcttctt gtttcaacaa cttattggaa tagatctcct gtattttttt gatttcctcc
     8041 aaaggaaaat aatggagaaa gattttttga gccggtgtta attgtgcatc ttgattcata
     8101 aagaagtcgg tcattcccag attctgattg ataaaatcat agatcatcgt acggatagat
     8161 cgttctgaac ctttataaac cagtccttgc tttccataac tgacgatctc tatcccataa
     8221 ctgaccagtg ttgctcgtaa ccgtctcata tcttcatcta atgtactttt agagatttga
     8281 aattcttctt cttttttgtt tagatggatc gggattcggc tgtaagcaac ggctaaaact
     8341 agatcaaaaa tacgttcgcg ccgattcaaa aagccgtctt tcacatcttt tatttcagtt
     8401 tctaatcgag cttgcttttc cttttccagc ttcaacaaaa aacctttgtt gcgaattgta
     8461 cggatctccg gaagcttttt actgctcaac cagatattcg cttcaagaac ttcctgacga
     8521 atcgtccgct gactgacatt gaactcactt gctagatgtt ttgcttttac tggatattgg
     8581 gctgtcatga ttctgtgaag tatttcaatt gttcttgttt tcatagaaat gatctccttc
     8641 tgatttcaag tatatggttc cgcttacata ataaaaagta gatatttctg ccacttgaag
     8701 tggaaagaaa gtaagcaaag caaacaaaaa ataagccata tgctttttca tctcctcaac
     8761 gaaaaagaca tacgcctatt attacaaaaa ttttgcccat ctatacaaaa aagaggttgt
     8821 gaaaaagctg tcctgcatca agtaataaga acaactaaac taaaatagtg cttcctattt
     8881 tttgtttggt tgttcttatt atcgcagatg caagctttta aacaccattt agtggagaag
     8941 ctgtgacaga gatgttcagc cttgagcgat aagaagcgat tttgaaaaat cgcttcccat
     9001 attttacaaa atcgtgcctt attgccgata ggctatctct ggaacaccgt ttattcagaa
     9061 aaaggagctg cgacaaggct tttgtcacaa ctccgttcat aaatatttcc tgtcaatcca
     9121 gcataatcgg ttgaataaaa tcggcttgcc atcttttttc tttctcagaa aaatcaaaat
     9181 accatatctg agaaaaatac tgtcgttgtg tcttacttcc tgagatcaat cgcccatctt
     9241 ttcgatcgac tgaataatca cagcatctga aatcaattcg gatggcaaaa ctattttcgt
     9301 ggatctgtcg ataatttcct acttcctgaa tagttatttt tttagtatga tttcttacac
     9361 cgtctgcttt gtttttttgc agaactttct gatgttcggc aaacagcttg tctgtataac
     9421 agcttctggc tttttcagga gtttcttctt cccaagcgga ttggatcttc atgaatatct
     9481 tttggatttc caaaaactgt gctttctttt ctttagccgt tcctgacatg cgggacaata
     9541 tctccgattt cagccttttc ttttgtcttt tattcttgac gatagaaaaa gcagaaaccc
     9601 ctcctactga caaaacagct aatgcaagaa accccgtttg ctcataacta gaaggacctg
     9661 tacttggacc ataataccca taagaatctc tgccgtaaga acgactgcca aaataactgc
     9721 ccccatatga acgaccgcca aatgaacctc tgcccgaact tcgaccgcta gatgtacctc
     9781 caccatgacc acccgcgaca gcgaatcctt gggtcggcag agcaaacaaa cataggccca
     9841 ctaacaaaat gattgctaaa taattgattt tttcattgtc ttcctcgtta tcttttatta
     9901 caaaaaacta ttttatcata gccttgctaa aaggaagagt caataaccag atgcataaac
     9961 tgttttttta gcaattttgt cttatttagt cattgagtaa catcggacag atgtatgtgt
    10021 cggcagtcca taattcctct atcttcagca tgaacaagct tgcagacaag agatctgcgc
    10081 ttcctccagg agagatttgg ttttcctgac aaaagtgcaa cagtgctgta aatggacgat
    10141 ttggtaaagc actttgacta gcagcatgag caagtttttg catttccact aacgttttct
    10201 gatcactgcg atgcaatacg catgtgtcat ctagcgaact catcaaaact aacaacatat
    10261 gcatttgttt ctgtacatat gaatcattat ctagctcctt agctgcttgg attgcaagcc
    10321 tgatatgcgg ataccctaat atcgcttctt catatgcacc atttacgcca tatttttgct
    10381 tcaccctatg accatgagtg gtttttttat gacgatattt tgtatcagga aaagcagcaa
    10441 gcttgctgac atcatcaagt attttcgata aagaaaaagg ctgttccata ctgatttttt
    10501 gtgcaatgac actgatcaat agccccattg cccaaatcgc tcctttatgg gtattgatgc
    10561 catttgtagc aatcagcatt gccttttccg cttttcgccc aatctcagca attctttctc
    10621 ttaactcctg atcaatagca taatgccatg ctatttgagc catttcttca aaaaaaggag
    10681 ttagcgtctt agcagactta tccaaaatgc gccgaccttc ttttacggct tttgcgatcg
    10741 tatggaaatt atcatctcct aaaaccatat cagctgcctg tttgcttact tcactacctt
    10801 tgattcccat agcgattcct atatcggctc ttttcaaagc aggtgcatca tttacgccgt
    10861 ctccggtcat tccgacgatt tctccatttt tctgcaaagc tttcacgatt cgcagtttgt
    10921 gttctggtgt cgttcgagca aagacgtcga cttttggtac ttgtcgaatc aactcttctt
    10981 cagacataag atccaaatcg atcccttcta aaactttagc agtatgtttt aagccaattt
    11041 gttccgcgat cgcttttgct gtatctttgt gatcccccgt aatcattttc actgagattc
    11101 ctgcttgttg gcattccttt acagctttga ctgcactttc ttttggcgga tcaatcaacc
    11161 cagcaatccc tgcaaaagtt aattgggtta aagactcatg cgtgagttcc tgtttcgaat
    11221 ctactttttt gtaagcaaat cctaaaacac gctgaccttt tttcgcaaac gctgtggctg
    11281 tttgacccca tgcttcttat tctgaagaag aaagagttga tttagccaat aatacttctg
    11341 gcgcaccttt gacgtaaatc acccctcctt tttcctccgc atgcatcgtt gccatatatt
    11401 tgtattcaga gctgaacgga atttttgctt ctattttttt caaaggcaga tcggctgttt
    11461 cggtgtggcg aatcagtgca agttctgtcg gattgccact taaattttct gttttctgtt
    11521 cttctttcgt ctttaattcc tgacaatttt tcataataaa cagtacgcga gtttcttcct
    11581 ttgctgctac atccacaact gtcatttcat tttttgtcaa tgtccctgtc ttatctgaac
    11641 agatcactgt catagaacct aatgtttcta cagaaggcag tcctttgatg atcgcctttt
    11701 cttttgccat ttcatgtact ccgacagata ggatcatggt caacacagct ggcaatcctt
    11761 cgggtaccat tgacaccacc aaagcgatca tagctgaaag aaggatatgc caatccatgc
    11821 catagcggaa tgttgtaaaa acaactaaga acaagatcaa acaaagaatg ccttgaaaaa
    11881 tttgtttgtt caatcggttg atcttcttga tcagaggcgt cgtttgttgt tcgaccgatt
    11941 gcagtgcttg attgatttta ccgatttctg tcgtgtttcc tgtttctaca acgacaccga
    12001 ctgcagaacc agattgtaca agcgttcctg aaaaagccat atttttttgg tcaccgattg
    12061 attcttctgc tgccaaaacg gaatgatttt tttcagatgc ttctgattct cccgtcaaaa
    12121 tcgattcttc tactagtaga tcatgtactt cgatcaaccg aacatctgct ggaacgacgt
    12181 ctccggcacg taagacaatg acatctcctt ttactagttc tttcgcaggg attttttctt
    12241 gcatcccgtt cgatagtact atcgcttctt gtcccatcag ctgcttcaaa ccattcaacg
    12301 attcttctgc ttttctttct tgccaataac taacgagtcc gttgacgatc actacgaata
    12361 aaataatact tccttcgatg tattcgctcg aagcaaattt caaaaaagag gcaatgatca
    12421 acacgatcat cagcagatca gtaaagtgtt ttgctatttt tttccatcgt tttgtctgct
    12481 gtcttgcttc tatctcatta tatccttgat cagtcaggcg tttctgccgt tcttcttgcg
    12541 acaagccttc tgttgatgtt tgatagtttt tcaatacatc ttctaccgtc aatctgtacc
    12601 agttcatcct atcccctcct gtttaattga tactgttatt atacgcaggg aagttttttc
    12661 aggcgtatcg attatttcag gggggtctga aataattcgt tttgcagaat gtatctgggc
    12721 ctaactgata tttctattgc ttattctttt atatacaaaa tttaagaata caaaccagat
    12781 aaccaataaa aaaggaataa agcgtgtcgt gctttcgaat aacaagctga aagcaattga
    12841 agtaaaaaac accaacaaag caagatcttt atatctttgt gtagtgttcc gtttcttttc
    12901 tttaataaat tgaacatgtg cacacaagat cgaagaccac acaaatagaa aacaactcgt
    12961 tgtcatgcct gccaaaagct gaaaaaacaa tcgactatca gctacaaaaa aaatgtagac
    13021 aaagaccgac aaaaaataac atccctgtaa ttaaaatacc gtgtaaaggt acgcctttct
    13081 tagaaagcgc acaaaaccaa tggggcaaac ttttctcttt tgctgtttga tataaaatcc
    13141 tgctagtact gtagactgca ctatttgctg aggacaaaga agcaaccaaa atcattagat
    13201 tgacaattgc tgctccgctt tggcaatgga tcacttgcag catagtcact aaaggacttt
    13261 cttttaaatc taaacaatgc catggaacaa caaataaaat cgacaaaatc gttcctatat
    13321 agaaaaagag gatacgccaa ggcagacagt tgattgcatt tttcaaattc ttttgtgggt
    13381 cactcgtctc accaactgtt aatccgatca tttcaattcc agcaaaactg aataaaacca
    13441 taggaaatga agcaatcatt ccagcaaagc caaacgggac taattcattg agctgtccaa
    13501 aatttgcttt gattccaata gactgggtat gaaaatctga gacactcaat cctataccca
    13561 ataagataaa aaggaaaatc cccaagatct tgatgattga gaaaaaagat tccaattcac
    13621 caaaccactt gactgcaaca aggttgactg ccattaagat cattagtgcg ctacctccgc
    13681 ttatcaaagc tggtacatgt acaaaccaga aatggatata caatcctatt gctgttaatt
    13741 ccgcaagtcc agctccaagc cagcaaagcc aataagtcca attgacaaaa aatgcccact
    13801 ttttgcctaa ataatagtca acgaaatcac tgatagagtt aaatgtacta tttgctaaaa
    13861 ataaatcacc catgacccgc atcaaaccat aaatagccaa accgcatatc aaataaacga
    13921 gaataacagc tggccctgct gatgcaattg cctttgctga acctaaaaat aatcctgttc
    13981 caattgcgcc acctaatgcg attaactgga tatttcgatt agttagagtc cgtttcattg
    14041 ccggtttttc catcaagttc acctttttct ttttcaagca gcatggcgac ttcctgttcc
    14101 caagaaggtt tctttatttt ttcaatacag agtggtacta caaacaaaat gacactgatg
    14161 gctgtgactg caattagatt gatccatgtc ccagctttca tcgtcagtcc gacagaaaat
    14221 ccgattgccg caaataaaac aataacgaca gtccaaactc caagattgct ctttttctct
    14281 ttttttccaa ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa tctcaaaact
    14341 gcgatcccca tgatgacata gacgatacag tagataacag tagttgaatt tacgagcatc
    14401 aaaaatgctt gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat tgagataatg
    14461 acagactgag tcaaaataac ggatttggat acgtcaaatt gattcgtctt ccaaaaattg
    14521 aattttggtg gatacgcacc ttttctagca ctttctgtca ctgtctttgc tggtcctgag
    14581 gcccaagcag ataattggac tgctacacca atgaagacaa gtaaactaaa cagattcaca
    14641 ataagatgtg gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc gatattattc
    14701 aattccattt gtccttttgg tacgacattt gctacaacta aagcattcaa aatattgacg
    14761 aaaaatataa aaattaacgc ggcaaatact ccgcgaatat acgttttaac tggatttttc
    14821 aaccgagtga tatacacaga ggacatttcg ataccagtaa aaataaacat gatcggcgca
    14881 aaataaacaa atgaggatgc agtcgtagta tctggtatta atttgtccca tgaaaaactg
    14941 cctaatgttc cggttggtac gatcccaact ttgatccacg cagcaaaccc taataagagc
    15001 atcatcgtca aaggcacgta caatcctaac caaacaccga cttttccgcc gatttttgcc
    15061 atatcaaatt tcaaattcaa aaaagtgatg atccaataaa cgactaaaat gacaactaat
    15121 gtaaatttgc tgttcaaacc aagcggcaca ttatcgataa tattaccaaa caacggagca
    15181 agtgctgaag cgaccatcac catcccagga aacatttgga cccataacag ccatgagaca
    15241 acgaaccccc atttttttcc tagagcattc gatacccaaa gttctggacc acctttttgg
    15301 ggaaacattc cggcaaattc accagagatc aatgagattg gaaaagcgta caataatact
    15361 gcaaccagca tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg aatatttcgt
    15421 acacttgcta caagggcgca ggtcattccg ataaaggtca tggtcgtgat ttgctttgat
    15481 gaaccagtat ctttcatctt tattccttct ttcaatagcg acatatgttt ttgttttctt
    15541 ttatttttgt tcaagaacag aaatgacaag gtttcatcga ttcagtacaa aacccagtat
    15601 caccgaaaca tccattgaac gatcttagtg aactgggttt gatacatgaa acgaacgatc
    15661 caacttatag aacgttttat aaaaaagaat atcttggcga ggaatatatg aaaaacaggg
    15721 ggaaatacaa ttgttttgat gaagcaaata attgtctgtt ctccatatgt ctcttgttat
    15781 tctttcacac aaaaatcagt tctattggat gatttcgttt agtttctttt ccattgcttt
    15841 ggcgatttct tttgtataaa aattgaaaat tcgatcatca ttcaaataag gagtcatgat
    15901 agccgcacgt agcagagtga ttttctgttc ttttttccat tcttctttcg ttagacccat
    15961 tctttcaaca aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg tagtatgaga
    16021 agtaataaac cgttcaccat aaacatcgcc atccatataa gaagaccgat cgaacatttt
    16081 ttcatttaat tcattgatag cgttcaaatc tgtacagcct tgttctttga atacccaatt
    16141 gaccatatta aaatcaggat gattcaatgg atagacttcg attgtttttc ctttaacagt
    16201 aaaagtcaga tgatcgagaa attctctgaa tctttgagct gcctcgattg aagccccaat
    16261 caattgacca tatccggtca cattcaatgg caatacacga tgtgctgtcc agactgcggc
    16321 ggcggttgct ccagcttttg atccttccaa aatataagct cctaacatat ctggagcctt
    16381 tactgatttt tcaaacacat atggcgcgaa ataagaaatg atatttctca tatttttatg
    16441 tttgattacg attcctccag cagcataagg gacatagccc atcttatgag gatctatcgt
    16501 gacagaatcc gcttctgaaa tagctctgaa cccttcatat acctctttgt caatcgttac
    16561 gcagtggtgg aaaacatgat gttcttcaaa gaattcagct aaggaagcat acggcacaaa
    16621 ttctcctgct tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg catcaacatg
    16681 taaatagaaa tagatccctt catcttttaa cctttctctt aattggacga ttttatctac
    16741 actgtctact tgaccttctt ctgtcgttcc tacgacagca accacaccta gaattgggat
    16801 tttttgttca gctaattcac gaattgtttt ttccaaagca ttaatatcca ttcgataatc
    16861 ctcttgaact gggatagcaa ccatctgatc taagcctact ccgcaaatat ctaacgcctt
    16921 catccaagaa tagtgttttg tttgaggcac cagccatttc cctaatcttt ggatattttt
    16981 tccgctacgg gaagaagctg ctttgacctc atccatttct tcgtccgtaa agctttcggt
    17041 catttccaaa atttcttcaa cagataaatt caaaagttcc cactcagaca tttttttcac
    17101 ttgttcaggc agcacttcct tgacagctaa aggaatcgat ttgatgcagc gggcgtacca
    17161 taatccttca agattagcaa tagaaccatc tgctgcaatg tgtccccatc cgtctgtcat
    17221 attgaataat gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag ttgccataga
    17281 agattccaat gcaacattat ttgggttcca cagcatcgca tagttgtaag ctaataaagc
    17341 aggcatcaat gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat gccatgggat
    17401 cgatcctgcg cgtaatcgct gactgacttc atccaagacc tctatcatat ggtcgcgggt
    17461 ggctagataa tctggagtga gcttatctcc ttcgctaatt gcaggcatat ctgaaggaat
    17521 ataattttct ctccatccaa gatgttcatc taccatcttg ttcaacaaca ttttataaac
    17581 tggtccattt tcagctttgt cgcctataaa gacggccttg atatccatat ctttcatttt
    17641 tcttccctcc atattttgtt ggtcaatgtc tcgcagatac atgtgtttat ctgtaacacc
    17701 tcttcactat agcgccaaaa atgagaaatt tttttttata acatcaaatc cacgtagatt
    17761 tttaca
//
LOCUS       DAXLPQ010000052        17490 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.052, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000052 DAXLPQ010000000
VERSION     DAXLPQ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.052"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            283..522
                     /locus_tag="ACF3UO_002135"
     CDS             283..522
                     /locus_tag="ACF3UO_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658098.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="ACF3UO_002136"
     CDS             complement(884..1144)
                     /locus_tag="ACF3UO_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658099.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="ACF3UO_002137"
     CDS             complement(1329..1826)
                     /locus_tag="ACF3UO_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFD3658100.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANLNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="ACF3UO_002138"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="ACF3UO_002138"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFD3658101.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="ACF3UO_002139"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="ACF3UO_002139"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFD3658102.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5210)
                     /locus_tag="ACF3UO_002140"
     CDS             complement(4548..5210)
                     /locus_tag="ACF3UO_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3658103.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5220..6035)
                     /locus_tag="ACF3UO_002141"
     CDS             complement(5220..6035)
                     /locus_tag="ACF3UO_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3658104.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6297..6740)
                     /locus_tag="ACF3UO_002142"
     CDS             complement(6297..6740)
                     /locus_tag="ACF3UO_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFD3658105.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6874..7212)
                     /locus_tag="ACF3UO_002143"
     CDS             complement(6874..7212)
                     /locus_tag="ACF3UO_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3658106.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7200..7577)
                     /locus_tag="ACF3UO_002144"
     CDS             complement(7200..7577)
                     /locus_tag="ACF3UO_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3658107.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7801..8994
                     /locus_tag="ACF3UO_002145"
     CDS             7801..8994
                     /locus_tag="ACF3UO_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3658108.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9160..9582)
                     /locus_tag="ACF3UO_002146"
     CDS             complement(9160..9582)
                     /locus_tag="ACF3UO_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658109.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9953..10627
                     /locus_tag="ACF3UO_002147"
     CDS             9953..10627
                     /locus_tag="ACF3UO_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658110.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
     gene            complement(10789..11961)
                     /locus_tag="ACF3UO_002148"
     CDS             complement(10789..11961)
                     /locus_tag="ACF3UO_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3658111.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12167..13465)
                     /locus_tag="ACF3UO_002149"
     CDS             complement(12167..13465)
                     /locus_tag="ACF3UO_002149"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3658112.1"
                     /translation="MHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYP
                     SKDTAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLS
                     LPFYNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQ
                     FVTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQ
                     KETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHF
                     IKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKL
                     ISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQ
                     PKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13593..14108)
                     /locus_tag="ACF3UO_002150"
     CDS             complement(13593..14108)
                     /locus_tag="ACF3UO_002150"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFD3658113.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(14181..15095)
                     /locus_tag="ACF3UO_002151"
                     /pseudo
     CDS             complement(14181..15095)
                     /locus_tag="ACF3UO_002151"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(15092..17419)
                     /locus_tag="ACF3UO_002152"
     CDS             complement(15092..17419)
                     /locus_tag="ACF3UO_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFD3658114.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5048 a         3474 c         3037 g         5931 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat tcaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa
     5041 agtaaagaaa aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct
     5101 gctatataca agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac
     5161 caataaaaga attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc
     5221 tattccttca ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat
     5281 ataaaagcaa caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca
     5341 tcaaatagcc caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac
     5401 aaataaatga atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa
     5461 ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat
     5521 aagccatcga tccgcgcact ctcacataaa gaatctggga tactactgta gtattgcttc
     5581 aacaagaaca caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatat
     5641 gttaaaccca cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca
     5701 gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa
     5761 aacccgtaag cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa
     5821 aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc
     5881 tctaaatgcc aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct
     5941 ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc
     6001 agcagaatca tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt
     6061 tttctttcat ttcgaacacc tccaaagtta taatcttcat ttctttgtaa tgattacaat
     6121 ccagaacaac ggttattata gctgattcat ttccgttctt cttatgtttg taagcgctta
     6181 tttaacaagt tatgtaaatc tctttatttt ttttgattta aaaatgaaaa aatacaaaag
     6241 caagactgtc atacgtctcg cttttgtatt gaaatttctt cgattagaga tacttattac
     6301 tgttcaaaag cttctttgaa acggtgaatc aattcattga ctacaggtga taaaatccga
     6361 ttctttttcc agactagcat gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc
     6421 actcgctttg aaagatgact tacagcacct tctatgacta aagcagcacc tacctgattc
     6481 tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc
     6541 ttttttatgc ctaaccagtc agcaaacatt cgctgtattt ctggacgctt tgagatcaaa
     6601 agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt tttttgctaa aacagaattt
     6661 tctaaaatga gcaatcccca tttttccttt cttggtaaca aaatcgtttc gtatttctct
     6721 gtatctactg gatctagcaa aatcgctaaa tctaacaggc ttttttctag tcactccgtg
     6781 atatcatcac ttgttccgct gtggatatga aattgaacgc tgggataatc acggatcaac
     6841 ttttctagta atagtgccaa tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat
     6901 cggccgctga ataattgttt ttttctgttc tcgaattctt gagtggtttg attcgttaaa
     6961 tctaaaattt cttctgctcg gcttttttag aaaataacct gcttctgtca agatcatttt
     7021 gcggttttcg cgtacaaaca gttctgttcc tagttcctct tctaactcct tcagttgtcg
     7081 gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct tgagagattg ttccttcttc
     7141 tgcaattgtc caaaaatatt ttagtaagcg taactccata gcgatgctcc ttgatttttt
     7201 tacttgatac attccatttt atttctagat aacacacgat catatttctt gatttttcct
     7261 tgtaaacgtt ccaaacattc ttgcatttca gcaatttttt tcgtcaaaag ttcactttct
     7321 tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc cttcgctaga taggcgaata
     7381 tattcaatca aagactcgat cgataatccg gcatttcgca tacagatcgt aaagtcgacc
     7441 cattttaggt cttcttctgt ataatcacgg attccgcctt ttgtccgatt aactggtgga
     7501 atcaacccga ttcgttcata atagcgcaat gtatcggccg aaatgccctt ttcttcactg
     7561 acttgtttga tattcatctg atcactcttt ctcttaattt cttgccactt tacttatgta
     7621 ttttatttat tctacaactt taagtgtact ccaagtcaat actcatttct attaaaacta
     7681 agctggatta tctatatcgg ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt
     7741 tattcttttt tggatatact tttaacaatt tagggaaatt ttaggaaaag gggtataaaa
     7801 atgacaacgt atcagcgaaa gttattatta tcgacatcgg cgggaattgc tttagagaat
     7861 atggatatta tgtttttagc tttttcatta tcttcaatga ttacttcttt tcatattagt
     7921 ggtacgcaag cgggtttcat ttcaacgatc actaatttgg ggatgctcat tggaggtatt
     7981 ttttttggca tcatagctga taaatatgga cgtgtgaaag tattttctca aacggtcctt
     8041 ctgttttcga ttgcttcttt attgatgtat tttgcttcaa acatctactt ggtttatctc
     8101 tttcgcttta tcgcaggtgt aggagcggga ggagaatacg gggcgtgtat gtccttgatt
     8161 tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt cggttgctgg tattggtgcg
     8221 caggtcggtg cggctttggc tgcgatttta gctgctgtga tcattccaac gtttggttgg
     8281 aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc
     8341 ttgactgaac caaaggaatt caaatctgta caatctgccg aaaagaaaac caaacttagc
     8401 agactgtttg aatcaaaaca tcttgcttgg caaacatgtg gccttagtat catggtaact
     8461 gtccaaattg ccggctattt tgggttaatg aattggctgc cttcaattat gcaaaatcga
     8521 ttagggcttt cggtttctgg gtcttcattg tggatggtca gtactatttt aggcatgtct
     8581 ttggggatga tgacttttgg cataatcatg gataaattgg ggcctaaact agccttttct
     8641 ttgtttttaa tttgttcatc cttatctgtc tatctacttg tgttagccca tagccagtgg
     8701 agtttggtag cagccgctgt gatagtcggc tactttatca atggcatgta tggtggatat
     8761 ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg cgacggcgaa taatttcatt
     8821 atgaaccttg gacgagctgt tggtggtttt tcttctatcg tcatcggttt cttgatggat
     8881 cattatagtt taactgccgt aatcttgttt ttgagcggta tttacctagt cagtctgctg
     8941 gtcttgacaa ctcttactgg tgttacagca ttaagggaaa gcttgcagca ttgatagttg
     9001 agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc atctgcggta ataagaccag
     9061 ccaaatcaaa aacatgagac actgtttccg tttggctggt cgtattactt gatgcagggc
     9121 agctttttca actgctaatt tccttctatc tggcggctac tattctttga cgtccgtcat
     9181 ttcaaagtac tttactaata acttagcata acgaaaaact gtggatacac tcgtatattg
     9241 agcgtctgca taatcttcca aatttttctc aggatgttga tacatgaatt caatcaaatg
     9301 ataattatat gattttctgt agaaatgaag ataaataatg tagattggga agttctcctg
     9361 cttttccata gaaaagcgcc gattattctc attcttcaaa atgaccttat caggatattt
     9421 ttggaacaat tcttctaaat ctgttagata attcaagata gacttacttg ataccttcaa
     9481 ttcgttttgt agttcttcta ttgaacacca acgttctgtt tcaagcagta aatgaatcat
     9541 tttaattttc ttttgagaaa cttttgttaa aaaagtctgc atattttctc ctcctgtatc
     9601 tactttacta tactacatac aagaaaaaaa acggatacaa atatcatatt gtcacaccgt
     9661 caatagtgca taaacctgtt attatttctc tttttttcct aagtattcta ttgatatgaa
     9721 tcatttaatc gtttattata taaatgtcaa taatctaata ataaaataac gtacatattt
     9781 tattattgca tacttaataa cagaactata gcaaaaaatc ccgtgtatca aaacgggatt
     9841 agattaagtt tcctcaatca ctattcataa cacaattatt ataacaagta agtaaacaat
     9901 tgaaaaggac atttattgaa aacggttgtt ttttacttaa ggaggaaatt tagtgaaaaa
     9961 attagttgca ttgtttttgg tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc
    10021 tactactcaa agcacaagtt cagctcaggc ttccagcagc agtaccacga tctccgaaag
    10081 tacggcagat tcatcgaaag aacaagaaca aattgaaaag aaaaaagaag aagagaaaca
    10141 aaaagcggaa aaagctgcac tagaaaaaaa agtgacagaa gcggaatctg ctttgtcaca
    10201 agctgaagca aatcctacaa aagaaaacta tgcaactgct tcagcagcta tccaagcgct
    10261 acctgaaaac aaacaagagt tgacaagccg tcttgctgca attgattcca caatcaaagc
    10321 aaaagaagca gaagaagaac ggaaaaagca agaagaaatt gcacgacaac aagcagaaca
    10381 agcgcaacaa gaagcaatcg cacagcaaca agcagaacag gcgcgacagc aagcagcagc
    10441 tgaacaggcc tctcagcagg cacaagccgc agctcctgag caaaataatg aacaaactgt
    10501 ctatgtcaca ccgaccggtt caaaatacca tacacataaa tgtggaaatg gtacgtatac
    10561 ccctgccact ttaagcgaag ctcaagctcg tggtttaacc ccttgctcca aatgttatgg
    10621 aaactaattc aaaagttata ctataataat aaaattcttc tgaaacataa aaaaatagaa
    10681 gctggcgttc cagatagtaa accaaaaata gcagtttaca cgtccatttc gtcagcttct
    10741 ctcttttttc atttagtctg ttccctctgc ttttttggac atcttcattc attctttctc
    10801 aatcaaatag tacacctctt tttcttttcg cagtttatat cttccttttt tcaatttcat
    10861 tgaaaactgt ttcgaatgtt tatgttttac atggatttta agcaggagct cctcatgttg
    10921 caagcgatag ttcctgcctt ttaaatcaga aaatctcact agtccgtatt catcagaagc
    10981 tttcacaaat ggaacttttt ctctagtaat atagtgtttg ccgttgagcg tttttacaga
    11041 aaagaccatt ccttcgattg gtcgtccgtt tgtgttcttt acataaaaag ataaaggata
    11101 gtttcgctta gcgatggcca aagaatctaa ataagcgatg agtagccaaa ctaagccgat
    11161 tgatccaagt agtataccga taaaccaaat aaaaaatttc cattttttcc attgatcaat
    11221 tccttggatc gctttttttg cctcttttgc ttgataagga atacgatgcc ccgtcacaag
    11281 cagtcgatgt gtattgacca tataaggagt acaggtaagc aaagtcacga gatctctgcc
    11341 tttttggata cccaaagaat ctacttcatc aggtaagacc acttggattt tttctacttg
    11401 atacgccaat gtctttccat tgatctggat gaaaaactgg tctccttttt tcaacttagg
    11461 caaatctgta aataattttg cttctgggag tccacgatgc ccagaaagaa cggcatgggt
    11521 gtttttcccg ccagtcggat aagaactttc ttccaataat gacgttcctt tttgcaaaaa
    11581 tatttccgtt gtctgatcga atataggtaa gctgacattg atttttggga tttcgatgac
    11641 tccaagcata tgttccataa aaaaggcatt actaggtaaa tcttttaatg cttttgcatc
    11701 aactgcttgg ttgaaactgc ctatccctgg tgatacgttt tgctctgcca actgttggtt
    11761 tttctttgtc attttttcct gctgtttttt tatttcctct gaattcttat tcgatgcttg
    11821 cttttgataa tggatgatca tttgctgggc aagaaaatca ttcagtgaat cttctacaaa
    11881 aggataagaa aagatcccga tcccaacgac taaaatgatt gccatgaaga tgtccagtat
    11941 tcttattctg cttttattca tcatgtccac ctattttcta atatgtatat gaagaggttg
    12001 tgaaatcagc gccttgacct gagtattcgc tcaacaaacg gcaaaatagt tcctcctatt
    12061 ttgccgtttg ttgagcgaat accaagagac cgaccacttg tcacaacctt tctccccatt
    12121 tgaatcacta tcgtttattt atcgtatgat ttttgtttcc aatagtttaa gcttctgttt
    12181 cttgatggcg ttttttgaag tagatcactg ctcctccaac taaagcagta cctaccaaga
    12241 tgaatacgat gatccccata ccaccagttg aaggcaagat tcctttaggt tggttatcga
    12301 tcgttgtttc atcagaagtt gttggatcat catctactgt aaattcagtg tacgcagctt
    12361 cattcttagg taatgcgtag ccttctggtg cttttgtttc ttgaaggcag tatgcccctt
    12421 gtttcagccc ttcgattgaa aatttccctt ctgaatcaga aatcaatttc acttcttccc
    12481 agtcagaacc tgtgacttca tctgaccaag catatgggta ttctcctgag gcaagatttg
    12541 ctattttttt cattaattta acagttggat cttttgctct tagaatagaa aattctgcat
    12601 cggctaattt ttcttgcgtg ttcacatctt gtttgatgaa gtggaaatca ccgtagtttt
    12661 ggacattttc tacagtaatc gtgttatccg tagttgtatt ttcccgattg actacaccgt
    12721 ttggattccc aagattggct tcatctgcgc catggatgat accggttgtt tgttgcaatt
    12781 ttccgttttt tactataaaa gtagtttctt tttgtggatt ggttaattga taaccatctg
    12841 gtgcttttgt ttcaactaaa gtataattgc cgtctattaa tccattgaca ctgatggatc
    12901 cttcagtatc agttgtgaat gtcaacgctg actcagcagg atcatagaga gcgacaccag
    12961 tgttttcatc aaaaccggtc acgaattgat tctctgaatt tttgatctgg aattgcgccc
    13021 ctgctaactt atctacccct gaaaagttcc cagctttctg gattttgata ttgctttctt
    13081 tgatgacatt tttagcatat aggtgaatcg tgtctaaagg tttgtcaggg tctgatgaat
    13141 tcgggttata aaagggtaag cttaacacga tatttggcga cgtttcgaca ccgggctttg
    13201 gtgtttctac aaagacgtat acagcatctt tcccatcaga tttacctgga agagtcaggt
    13261 tagctaatcc ttcaccagaa gtcgttacac ttgcgaaggg tgtagcgtct gctggaactg
    13321 ctgtgtcttt acttggatag tacgtagcag tgatgtcata tacgttgaat tcaacgccgt
    13381 tcaacggttc gctattcgga aatgtcaatt ccgttccgtt gtttatttga ttttctggtg
    13441 ctgaagtgaa tttcaattta tgcaaattaa ccgtaacatt ttctggtgta ggtgatacgg
    13501 cctagaaacc tctgcagttc ctaggccgag aacgaaagga agcagcatga tagcagttcc
    13561 taaaaacgtc catatttttg ttttgatgtt tttcatttta tttccctcct attgtttcct
    13621 ttttgttgtt ttttataaaa ccaagctgtc cctgttgaaa ggactagcaa caaccctaaa
    13681 attgagaaac ctccaagcat ctcttcgctt gtttttggaa agcttcctcc atttttttca
    13741 tttgatggac catttgtctg catctgaact ggcgtttttc cattattcgt cggatttgct
    13801 tttggttcgt tgatgatttc caatggtata ggatgaagcg gatcataact gcctttttca
    13861 acttcaaaga gaatggttga ttgactcaat atatatcctt taggcggttt aatctccact
    13921 agttcgtaac ttccaaaaga caatccatgg acagaaaatg ttccatcttt actggaagta
    13981 aaaatcgttg ctcttgaatc atctttggct acccaatgat ttatcccgtt ttcttgcgct
    14041 aagtattggt catttttttt gactagaaat tgagcatctg ctagtttttg tttcgtttgc
    14101 cgatccactt tgacaaattg tttgcctcct gtttggatgg caagatgtgt ttctactgtt
    14161 tgattgtcag tcgtcaaacg tacatcgtta tcaaatgtcg ttttttcact gttttctttc
    14221 aatgtcattt ggtaacggat cgttaatttt ttcccagcaa acgaactaag atcttttcca
    14281 gaatctgata agacaaaacc atgttttgtt ttttgtgtgt gaaatgtatg aatcttgtct
    14341 ccaccaatca aaaaatcgat cgtttctggt tctagccata actgaggatc agctgtatct
    14401 ttgatcgtat aggttcctat ctcgttgatg ttctcaggaa ttgttacggt gatgagataa
    14461 ggaactttat ccccatctgc aaaatctgtc tgcttattct ctactgtttt tgttaatgtg
    14521 agtgcagcag gtattttttg ttcgctcttt ggatacaagt ggatggtcgt caatttatga
    14581 ttagatgaat ctgtcacagg aagcacaacg acaaatggtg ctgatttttc ttttacttaa
    14641 tctgaagtct ttatttccgc aaatcggtaa acagcgtcac gaccttgctc atctttgtcc
    14701 gatgcactaa aagaagcaat gccctcttcc tcgtctactg tttttgtcac attttctgcc
    14761 agtatttttt cactatcact tttttgtgct agttttcttt gtgcgtcttc cacactactt
    14821 ccttctgacc gcagcttgta aaattcatcc gagacatcat atatagcgaa agtaacgccg
    14881 ttcaaccctt ttactccttg aaagttatcc gggatattta ttccgtcgtt ttgactgata
    14941 cttggcatct tatcgctttc gaacattcga ttatgcaaag taaatgtaat aggtgattct
    15001 ctagctgaca cagtcggaga acctataaaa aagaccagta ggataaaaaa gagaacagca
    15061 aatatatcca cacgtacatt ttttgttttt ttcatcgctg ttcacctgct tttttcttac
    15121 gatggataaa ataaaagaag ccagaaaaaa taaagatcag tcctaaaaag acaaagggca
    15181 gtagacctat cccacctgtc gaaggaagca agagagtcgg attgatcgtc aacttagcgg
    15241 tatctgttgc gataatcgta taattattgt ttacacttcc ttcgcctaaa ctaatcgtta
    15301 ctatttgtga tccaatatct gtccggctgt taactgttag ggtataatcc aatgattcgc
    15361 ctaagacaac accggtaacg tggagatttc caaccgaaat cgagtgactt tgggcatcat
    15421 aattaaaggc agcgtcatcg acagtaatca ctgcgttagc tttatagatg gtataagttc
    15481 ctgatgtgtt ggctatatca gtaaatgaca acttgggatt tgctgctttg actttgtcta
    15541 ttccgctatt cgttagttta attgtatagc tgccagcatt aaccatattt tttgctgatt
    15601 gtgcatctgc tgtgtaatcc atactgctaa gtgccacttg tactggagta agcgaactag
    15661 tgacaccctc tgctagcttg acatggattg acgggacacc tgcttttcca tcatatgtct
    15721 tactgccact gagctctacc gcaccgctga tttgcttaat cgtatagaca tcagatgtct
    15781 gcacgatagt aaataaatag tttgttctgg cagctagttt agctagtccg ctttttgtca
    15841 attgccaaga cgtataggtt ccaatttcag taggcgcagt tacttcaact cccttttcat
    15901 tcatcgcttt gaaatcagtt ggattccatg tgatttgatc aatactgaga tcattgttta
    15961 aaagggatgt tgattctgtt ttatcattaa aggcatattt aacgatcggt acaacagaaa
    16021 gaccatcata gtacttactg ccatttgcat tgattgatac tgttgcattt gtcttataat
    16081 ataggatgac ttcagaaatc tgttttccat ttgcgtcctt tacgattaca tttccatttg
    16141 tatctaaact agctaaaaca ctcattgctg attggttctt tgtttctgtc gctgaaacag
    16201 ctgtaaaggt atatccgttg atagtaggcg tattagtcgt caggtcttgt gcagcacttc
    16261 cgtaagtaag attcattatt ttagaaggag caatcatctg tccaaaatag tcttgatact
    16321 taatagtgat tggtgtttgt ttgcctgtat aggtcaccgt atcgacgtta ctttctaggg
    16381 ctgtgaaaga accgtttgtt tgtgcaaaag aatagcccgt tactgctgtt ggagtgataa
    16441 ccactttgtc acccacatgg attccagata atgtagtccc gtacgttccg atttttgctg
    16501 ctccaccatt gactgtataa gaaaaagttc ctgtccgatt cgcattgacc tgaaccgttg
    16561 ctgcttgata ggttggaaaa tttgaaacat ttcccttacc atcaacgatc tgcccatttt
    16621 tgatcgagta ccccgtgaat ggaatatcat ttgctaactg tataccgatt gaaaaagtac
    16681 tcatacctcc tccggcagga agccctcccc atgttgaggg tgtaaaagaa taacttttat
    16741 ccgcattggg tgtaactgaa tcgatcgtat ttccagcggt agccaccccc atatagatac
    16801 tttttgggaa tgtgatagta gtaccattta ctgtggagcc aataaacaga ttatggatat
    16861 ctggacggtt atcaataaaa gcgattgctt tggttacgcc ttgtaacgca gttttatccg
    16921 cactcatcga tccgttaacc gcaacaatga ctccatcttt ggcatatatc actgtatatc
    16981 catctggtat ggtatgtccg ttgaaattcg cagtggccgc aacagtacta aatgtctggc
    17041 ttctacctgt ttctgaataa gctttctccc ctgctgcttt tgctgctgtg atttcttttt
    17101 ctgtcggatc aatcagttga gtcgaggatg tggttgaggt tgtctcgttg ttgctagact
    17161 gattggtgct ttctatggac tgtatttcag aatagggtgg actatttgtc tcctctgtcg
    17221 tttggttagc aaaatttgac gtttctgtat aaacgtttac ataaatactt gataagctcc
    17281 ctaagaaagt aaaaatcaag atgatcgaaa tcataatggg atgtaagtat tttcttttag
    17341 atacagcttt gagtctagaa acaaaatgtt tttgacatat acgttggatt ttattttgag
    17401 ttttcttaat cattttcatc cctcctctca ataaaaaatc atcaaataat cctttacacg
    17461 ttattctaaa tttaattttt attattttat
//
LOCUS       DAXLPQ010000053        16200 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.053, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000053 DAXLPQ010000000
VERSION     DAXLPQ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.053"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            52..933
                     /locus_tag="ACF3UO_002153"
     CDS             52..933
                     /locus_tag="ACF3UO_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3658115.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            936..1706
                     /locus_tag="ACF3UO_002154"
     CDS             936..1706
                     /locus_tag="ACF3UO_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658116.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            1985..2839
                     /gene="aroE"
                     /locus_tag="ACF3UO_002155"
     CDS             1985..2839
                     /gene="aroE"
                     /locus_tag="ACF3UO_002155"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFD3658117.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            3017..4180
                     /locus_tag="ACF3UO_002156"
     CDS             3017..4180
                     /locus_tag="ACF3UO_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3658118.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            4297..4707
                     /locus_tag="ACF3UO_002157"
     CDS             4297..4707
                     /locus_tag="ACF3UO_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3658119.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            4881..7109
                     /gene="topB"
                     /locus_tag="ACF3UO_002158"
     CDS             4881..7109
                     /gene="topB"
                     /locus_tag="ACF3UO_002158"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFD3658120.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            7280..7564
                     /locus_tag="ACF3UO_002159"
     CDS             7280..7564
                     /locus_tag="ACF3UO_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658121.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            7724..7960
                     /locus_tag="ACF3UO_002160"
     CDS             7724..7960
                     /locus_tag="ACF3UO_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3658122.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            7957..8356
                     /locus_tag="ACF3UO_002161"
                     /pseudo
     CDS             7957..8356
                     /locus_tag="ACF3UO_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(9023..9967)
                     /locus_tag="ACF3UO_002162"
     CDS             complement(9023..9967)
                     /locus_tag="ACF3UO_002162"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD3658123.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(10263..11207)
                     /locus_tag="ACF3UO_002163"
     CDS             complement(10263..11207)
                     /locus_tag="ACF3UO_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFD3658124.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            11428..12642
                     /locus_tag="ACF3UO_002164"
     CDS             11428..12642
                     /locus_tag="ACF3UO_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3658125.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            12664..14679
                     /locus_tag="ACF3UO_002165"
     CDS             12664..14679
                     /locus_tag="ACF3UO_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFD3658126.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(14762..16135)
                     /locus_tag="ACF3UO_002166"
     CDS             complement(14762..16135)
                     /locus_tag="ACF3UO_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3658127.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
BASE COUNT         5359 a         2852 c         3173 g         4816 t
ORIGIN      
        1 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
       61 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
      121 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
      181 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
      241 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
      301 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
      361 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
      421 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
      481 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
      541 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
      601 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
      661 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
      721 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
      781 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
      841 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
      901 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
      961 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     1021 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     1081 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     1141 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     1201 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     1261 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     1321 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     1381 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     1441 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     1501 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     1561 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     1621 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     1681 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     1741 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     1801 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     1861 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     1921 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     1981 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     2041 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     2101 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     2161 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     2221 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     2281 tttgattggc tataatactg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     2341 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     2401 tgttcaagca gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     2461 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     2521 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     2581 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     2641 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     2701 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     2761 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     2821 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     2881 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     2941 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     3001 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     3061 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     3121 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     3181 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     3241 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     3301 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     3361 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     3421 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     3481 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     3541 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     3601 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     3661 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     3721 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     3781 tctggatggt gtagatatta aaaaaggggg ccagaagatg gatggacatg ttcttttgca
     3841 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     3901 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     3961 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     4021 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     4081 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     4141 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     4201 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     4261 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     4321 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     4381 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     4441 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     4501 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     4561 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     4621 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     4681 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     4741 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     4801 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     4861 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     4921 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     4981 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     5041 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     5101 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     5161 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     5221 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     5281 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     5341 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     5401 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     5461 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     5521 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     5581 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     5641 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     5701 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     5761 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     5821 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     5881 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     5941 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     6001 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     6061 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     6121 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     6181 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     6241 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     6301 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     6361 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     6421 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     6481 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     6541 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     6601 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     6661 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     6721 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     6781 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     6841 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     6901 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     6961 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     7021 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     7081 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     7141 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     7201 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     7261 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     7321 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     7381 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     7441 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     7501 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     7561 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     7621 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     7681 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     7741 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     7801 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     7861 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
     7921 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
     7981 attatcaaaa tcaacgcgaa agttatttta ccgtcactcg ccaggcgaaa tgatcggtgt
     8041 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
     8101 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
     8161 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
     8221 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat
     8281 taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca
     8341 aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta
     8401 aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg
     8461 aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag
     8521 gaaatagtgg tttagaacta gtgggctgat tttttatata ttttagttta cataatatat
     8581 attatacaaa gtagatttaa aaaatgataa acctctctcg aacggttttt tatcaaaaat
     8641 cgtcattttt ccatcaaaat ctgcttatgc aaaattataa aaaaattttg cagtttttct
     8701 tacttttttt gtcgtttaat tgaatgataa aaaccagttt ctttattcag ttaatcaaat
     8761 atgaacgaat tagatatgaa tcattgtatt tgccgttgcg gaaggatttt ttaattaacc
     8821 acagataaac attgataacg attcgcttat tgtaatcaac agattaaatt tcatatgttc
     8881 atatgtacgg atacattttc ggaccgatta attttaacca ttctgtttat ttgcttacct
     8941 attagatatc aataaaaaac tgcttaacag ctatttcagc tgttaagcag ttttaggatt
     9001 tttagttcat attcattgtt tcttataata cagtgttcaa tacttctctt aaagcacttg
     9061 ttgatttgct gaacattgct ttttcttctt cgttgattga taattcaaca acttcacgaa
     9121 caccattttc gtcaacgatt gatggcacac ctgtaaagat atctttttcg tcgtattcac
     9181 cagttaaata agcagataca ggcaatacag cttgttcgtt attcaagata gcttttacga
     9241 tacgtgcagt actcatacca ataccatagt aagttgcttt tttacgatca atgatctcat
     9301 aagcagcatt acggacttta tcagcaatca catctaattc atcttgggca atacgatggt
     9361 ctttttctac aatttcaaac actggtttac caccgacagt tgtatgtgac catgcagcaa
     9421 cttctgaatc accatgttca cctaagatat agccgtggac gctgcgtggg tcaactttta
     9481 atttcaatgc gatttcttta cggaaacgag ttgtatccaa tgttgttcca gtaccgataa
     9541 cacgtgatgt tggcagacca gattcgttcc aagcgatata tgtcaaaata tctactgggt
     9601 ttgaagcaac aacgataata ccgtcgaatc ctgatcccat gatttctttt acgatttggc
     9661 gcatgattga cgcatttgtt ttaactaaat ctaaacgaga ttgaccaggt ttttggttga
     9721 taccagctgt gataacaacg atatcagcat ctttacattc ttcatagcca cctgaccata
     9781 cagccacatt ttcatcgccc caagccatac catctaaaag gtccaatgct tccccttctg
     9841 ctttttcttg attcacatcg atcaatacta attcattaga gattccttgg ttgatcattg
     9901 cataagcgat acttgttcca acaaaacctg taccgacgat tactacttta cgacttgttt
     9961 ttttcatgaa taaacagctc cttttcataa ctatttgtta ctttcatgaa aagtatagtc
    10021 ttgtttattc attttatcaa catgttaatt ataatagttg ttattataat ttttgatgga
    10081 aacgaattcc tgaatacgca taacagataa atgacaaatg tttacaccta tatcccctga
    10141 taatacaacc aaaagtttag aactgaaaat aaatccaaaa aaattcgctg caacgatata
    10201 ataagacagc aatcgcacct aaaacaattt tccttcatat gctttagtga aagattttct
    10261 tcttaatgtt tatttctcca ttcattggga gtacatgttg aatacttctt gaataatttg
    10321 aataaagaag tcgtttgttt atatccgata cgattagcga tttcttccaa cgaaaaactc
    10381 gtttcttgaa tcagttccaa cgcaaagtcg aattttttct ttagaaccag ttcttgaaag
    10441 gaagcatcaa aatacatttt caatttatta ctaagataga ccggattgta gccaaaatga
    10501 gctgctgttt cttttaacgt acaagaagta aaatgcttat cgatataatc taatactcta
    10561 agcatctcat tttctgcgca tccatctgct gatgaaaagc tttgttgttc taataaatga
    10621 gtcaattcga tcagtaatag tgatgtatag agatttaacg aacggatctt atgactgtat
    10681 gtatcaaaat aaatcaacag catattttca atcaaatgcg tcaaacgact tgtttttccg
    10741 ccgcgaaaat gaatgaattg tgtatgttcc cctttttctt ttgatgcatt tatcaaaaaa
    10801 gaagaaagta gattatttgt gcttgccaaa tgattcaata tctctgtaga taaggtttct
    10861 tcttttaata agatgttgat taaaatatcc tcttgccctg tgtattcgat tctttgagta
    10921 gcttctttat caatgatcac cacgtcactt tcttccatct ctatcctttc tccattaata
    10981 atttgtaaac atgtaccgct atacatataa ttgatttcaa caaaatcatg tgtatgctcg
    11041 ggaacttccg catatcgacg gtgtttactg atatgaatat ttccctgttg aaatagatcc
    11101 cctcggtgga tttttggcgg tgtctgaaga tggtaagcta agtttaaatc attgatattc
    11161 attccttgtt cacgctgcag agtttcgatt gattcttcgt tacgcaaaaa aaatgtctaa
    11221 ttcagctagt tccaattgac tccctccttt ttgtaagcgg tttctttcgc ttattagttc
    11281 acgctgtact gctattatat gcaaagctat ttttggtttc ataaagactt tctatggttg
    11341 ggacatgaac ttcctgtgat tccgctattg agagaataac cacttcatac tatatttttg
    11401 ataagcgctt acaaaaatga aaggaacatg cttatgaata aaaagatgat gaaattttct
    11461 ctgctgtcag tctctcttat tttgacttct gctggtgcag tcacgtctgc aattcccagt
    11521 atgtcagcta cttatgccac gcgttcttta tctgctgttg aattattaac gactgctccc
    11581 tcttttatgg tcactatttt tgttttgatt agtagtttta ttgctaggaa aatcggacaa
    11641 aaacaaactg tgatcatcgg attagtgatt gcatcgattt gtggtatcct ccccctcttc
    11701 tcacaaagtt acagtattgt cttagcttca agagctggac taggtattgg ctttggattg
    11761 atcaattctt tggcagtcag catgattgct gccttttatc acggagatga acgagcctct
    11821 atgattggtt ttcaaagtgc atttcaagga tttggtgcag ctttaatgac atttgttgca
    11881 ggacagctag tacagttcgg ttggcaatat acctttttag tctacgccat cagcttacct
    11941 attcttgtct tgtttgtttt gtttgttcct acacctgaaa caactgaact tcaatcgcat
    12001 ggcacagccc caacaagaca agtaatcaaa acgaatccta aaatgattag ttatggtatt
    12061 tttctcttgc tggtcatcgt ggtatataat gctgtatcga ttaaattagc cacagtcctg
    12121 acgacttatt ctctaggaaa cgaaactaat gcagcgaata tcttaacaat catgcaattg
    12181 gcaagtatgg ctgccggagt ttgttttggc tggcttcaga caaaagcaca tcgctatatg
    12241 cttacacttt ctttactact gatgggaatc ggctttgtat tgattgccac tgtgataaac
    12301 ctgtatgtga ttgggtttgg tgcgatccta acaggaattt ctttttcgtt attcattcct
    12361 tacttattca accaagtaag tatccaagcg cccaagtacg cggagagttt caatacttca
    12421 atcttattgg ttggcgctaa tttaggtact ttcattgcac catatggttt gctctttctc
    12481 tcttttgctt ctcttgggag taaaacactt gctgttttcg tcaatggcag tatcttgctg
    12541 ttgattagcg cgcttattag ccttctagta gtacacagga cgaatagaaa gacagtgata
    12601 agagtagatg aagaaataaa agaacaattg acaacaaaat aaatttgatg gaggtcgtgt
    12661 aaaatgacaa atgaaaaaca taaagataga tggctttggt atcctggaga ctttgagatc
    12721 cgccatggac tgctacaaaa tttccaacgg gaagaacgag gttttgactg gccagcgtac
    12781 tggtacatgg atgattgcca tcggaacgtc aagtttaaga gatattactt tcttgatcaa
    12841 ccttccatgt ttaaagtgac gatccaagga gttgggtatg tagaaattaa tggacaaaaa
    12901 catccatgtg gaaaatggct gacttgtcca gctggtaaag caaaaattcg tatctttgta
    12961 ggacatacat cagggctacc agcgatgttt atcgagggag acgaagtaaa atcagatatt
    13021 ggctggacag caagtaattt tattgaagaa tatccagctg gctggagtcc gctttatgtc
    13081 gatatcgcaa aagatccaaa tcaaatctat tatcaaaaag aatgcgtcca tccagtcact
    13141 gaaacggaga ttggcggagg aatcttattc gattttgggc gagcagtgaa tggctgtgta
    13201 gaactaatat ctctggatga ccatatcgaa tctatcactc tatgttatgg agagtccgat
    13261 gtagaagcta tggatatcga ttattgctac tataagcaaa taggaatgac aagaaaaatg
    13321 aaagctcgta aacgcgcttt tcgctatttg tttataccag aggtttctac tggaatggtt
    13381 caacttcaag tttttcatga atttttatct ctttcgaaac aagctgcttt ttcaagcgat
    13441 tcttctttac tgaatcagat ctggtcagta tcagaagaag ccttcaagtt atgtagtgat
    13501 ttgtttttta tcgacggtat caaacgagat cgctggattt ggtctggaga tgcgtatcaa
    13561 tcattcatga tcaatcaata tctttttttt gacgaggaaa tcaataaacg aacgatatta
    13621 gcattaagag gacaaaatga aatcaagcag catatgaata ctatcgttga ctattcgatc
    13681 ttgtggttga ttggtatcga aaaccactat atgatgacga aagactatga atttttacgc
    13741 atcgtctacc ctaagatgca atcattaatg agatacttga tggagcaaac gaatgaatta
    13801 gggtttattt atgggagagc aaaagattgg atatttattg attggtctga aatggataaa
    13861 gaaggaacgc ttgctgcaga acaagtctta ttactgaaag cctatcattc catgatcact
    13921 tgcggagata tcttagctga aacatatgga gagaacgaaa attatcatac tcatctctat
    13981 caagaaaaat atcaactatt gaaacaaaac ctatttgact acttttggga tgaagaactt
    14041 ggcgctttta tcgattgcta tgaatctggg agaagaaatg tgacgcgtca tgcgaatatt
    14101 ttcgctgttt tattcgattt tgctaacaaa gaccaacagc aatcgatctt aaagaatgtc
    14161 ttattgaatg acactatcac acagattact actccatatt tcaaattcta tgaacaagat
    14221 gctttatgca aactcggaca gacgaatatc gtctaccaaa cgattcttga ttattgggga
    14281 gggatgttat ctcatgatgc ggtaactttc tgggaagaat acgaccctac tcaaacagga
    14341 aatgaaaagt acagtatgta tggagatcct tatggaaaaa gcttatgcca tgcatgggga
    14401 gcaagcccaa tctatctttt aggacgctat tttatcggtt tgtatccaac aaagccaggt
    14461 tatgaagaat ttatgataca acctaatcta gattcatttg aaacactgaa ttgtacgcta
    14521 cctatcaaag atggaaagat ttcgcttgaa aaaacaaaag ataagatcgt gattacttct
    14581 gatagaacag gcggaacagt gaaaatgaat ggtaaaagtt atcctcttct agcaaaacag
    14641 ccacttgtct taacaagcta ttcaaaaata aatgcataaa acaaaaaact gcttgcgaca
    14701 tatcagaaga ctttaaatct tcttctgata ttgtccaagc aatttttatt ttgaagtttg
    14761 cttaattctg ttctttagaa acaatgtttg ttctttttcc ggcaaaaaga aagctagata
    14821 atacgacaag taaaaagaaa gcgatgattc caactgtcaa ggctatttga ccgtattctc
    14881 ctagtttccc aagtacaagt cctggtacta gataatcagt atcggcaaat gtagaagaag
    14941 cgattttaag atctcctaat actggaagga taaataatgg cagccaacta atcaataagc
    15001 tattgaaagc agaacctaat accgcccctc ttctaccgcc agtcgagttg ccgaagacac
    15061 cagaagcagc tccgcagaag aaatgtccta ctaccccagg aatgataact gtagtttgca
    15121 agcctatcat agcaaacatg gatagtgttc ctacaaagaa gctaacaaaa aagccaatta
    15181 atacagcatt aggtgcatat ggaaaaacga taggaacatc taatgctggt ttagaatcgg
    15241 gtacgagttt tttagcaatc ccttggaatg ctggaacgat ttctgccaac accattcgaa
    15301 ccccttgaag gacgataaca aacccagctg tgaatgttcc agcttggatc agtgcaaaga
    15361 ttacagcgtt gtctccattg cttagttctc tttcaacaaa tccaggacca gctaacaaag
    15421 caagtgcgac atatacgatc gacatcaaga gcatgatcga tacagtagaa tctcgcaaaa
    15481 agctgaaact tttaggaatc tttatgtcct ctgtagaacg gtctttgttt ccaaaaaact
    15541 ttccgatcca tccactagaa gcataaccga tatttccggt atgccctaac gcaacttgat
    15601 tgtttccagt gatgttcttc ataaacggtt gacaaagagc aggcgtaata gttaatagtg
    15661 ttccttcgaa gaccccgcct aataagatca tccacaaatt tgcagtaaac cccgcgctta
    15721 ctaaaatgac tgctgttaga caagaaacat aaagcattgc ttgacctgta agaaaaatga
    15781 atttatatct tgtgaatcta gcaagtaaaa tattcacgat catccctact agcatgatca
    15841 aagcagtagg tgtaccgtat tgttgcaaag caatcgccac tactgcttca ttgctaggaa
    15901 ctactccttg agtatgcaga gctgtttgga acatcgaagc aaaaggggtt agtgaattac
    15961 tgattaaacc agcaccgccg atcagtacta ggaatccgac aaatgttttg atagttcctt
    16021 ggatcacttc tgaaaatttc ttcttctgaa gaacgagacc aagcagtgca atcaaagaaa
    16081 cgaggatgga gggctgactg acgattgaca caaacaaatt caacaattta tccattgata
    16141 gttcctccct tgaatcattt ttattctttt gacaagatct tcgttacttt ttcttttact
//
LOCUS       DAXLPQ010000054        15937 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.054, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000054 DAXLPQ010000000
VERSION     DAXLPQ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.054"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(174..476)
                     /locus_tag="ACF3UO_002167"
     CDS             complement(174..476)
                     /locus_tag="ACF3UO_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3658128.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(696..1062)
                     /gene="ssrA"
                     /locus_tag="ACF3UO_002168"
     tmRNA           complement(696..1062)
                     /gene="ssrA"
                     /locus_tag="ACF3UO_002168"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1233..2006)
                     /locus_tag="ACF3UO_002169"
     CDS             complement(1233..2006)
                     /locus_tag="ACF3UO_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3658129.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2150..2500
                     /locus_tag="ACF3UO_002170"
     CDS             2150..2500
                     /locus_tag="ACF3UO_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFD3658130.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2481..3197
                     /locus_tag="ACF3UO_002171"
     CDS             2481..3197
                     /locus_tag="ACF3UO_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFD3658131.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3197..4645
                     /locus_tag="ACF3UO_002172"
     CDS             3197..4645
                     /locus_tag="ACF3UO_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3658132.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4715..5224)
                     /locus_tag="ACF3UO_002173"
     CDS             complement(4715..5224)
                     /locus_tag="ACF3UO_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658133.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5214..5938)
                     /locus_tag="ACF3UO_002174"
                     /pseudo
     CDS             complement(5214..5938)
                     /locus_tag="ACF3UO_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6161..8281)
                     /locus_tag="ACF3UO_002175"
     CDS             complement(6161..8281)
                     /locus_tag="ACF3UO_002175"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3658134.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8511..9689
                     /locus_tag="ACF3UO_002176"
     CDS             8511..9689
                     /locus_tag="ACF3UO_002176"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFD3658135.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9705..10463
                     /gene="aroD"
                     /locus_tag="ACF3UO_002177"
     CDS             9705..10463
                     /gene="aroD"
                     /locus_tag="ACF3UO_002177"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFD3658136.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10486..10971
                     /gene="ybaK"
                     /locus_tag="ACF3UO_002178"
     CDS             10486..10971
                     /gene="ybaK"
                     /locus_tag="ACF3UO_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFD3658137.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11042..12295)
                     /locus_tag="ACF3UO_002179"
     CDS             complement(11042..12295)
                     /locus_tag="ACF3UO_002179"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3658138.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12412..13761
                     /gene="gdhA"
                     /locus_tag="ACF3UO_002180"
     CDS             12412..13761
                     /gene="gdhA"
                     /locus_tag="ACF3UO_002180"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFD3658139.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13873..15219
                     /locus_tag="ACF3UO_002181"
     CDS             13873..15219
                     /locus_tag="ACF3UO_002181"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFD3658140.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15527..15913)
                     /locus_tag="ACF3UO_002182"
     CDS             complement(15527..15913)
                     /locus_tag="ACF3UO_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3658141.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5216 a         2844 c         3191 g         4686 t
ORIGIN      
        1 acttataatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
       61 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatcccttt
      121 tataagtatg gtgataaaat ccgttccggg ctaccttttt taggtagcct actttaatct
      181 ttataccttt ctggatcaac gaaagtatac ttcaaatagt cataacgccg atgatcgctc
      241 cgtgcgtctg gcacatcagt cacgatatca aacaaaaaat acacatcttt cttcattctg
      301 gtttttgttg ccggaatttt aaagtagttc ttattagagt aatagagatt gattaataag
      361 ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca
      421 aatctattcg aaggatcaaa tttaaaccat aattgtgttt ttccttccat caacataatg
      481 ttcacctcaa aaagagtata cgaactaatg ttctttttgt aaagtaggaa tatcattgat
      541 aatatggatg gaacatatat attaaaaagt gttctttttg aatgctattt tgaatgccat
      601 tttcattcat ttaacgaaaa tctgcgaaaa taaaaaatgc tcaaaccctt ataaaataag
      661 gatttaagca tctagcgaaa tctgctgaaa tctcacaatg gagacggcgg gagtcgaacc
      721 cgcgtccaaa cacatcgcca cttaaaaatc tacgttcata gtcaactcat ttaaggattc
      781 actttacagc ttgccgagtg acaggcattc tgtatcgcta gtctgatgtt ctctttttca
      841 acttacagac ggaaagttga aacgtatccc actaaagtta ggacccttac tcgagcacat
      901 gggcgatgcc gagaggatct acgctaactg tttttaggca gctaaagcgt aagagttgtt
      961 ttcgttttta gcagttatat ttaactgtaa cgtttttacg tagacgtaac ctacgaaacg
     1021 caattcaagc tcgactgtgc ctgtcgaatc cgtaacgtcc ccgttagcta acaagggtta
     1081 cgtgtatttt tcatacaaaa ttagtatagc atatattggg ataaattcaa taaaaaagcg
     1141 aatcatatcc cattatttat ataataactg cccctttctt aagaaaaaat aagcgatttt
     1201 cttaagaaaa gaggtagctt caaaaaaaga tcttaaatca gatcaaaata cttcaatgcg
     1261 tggacaattc cgccttctgt atttttcttt gtgataaagg tagaaagttc ttttaatccg
     1321 tcataggcgt tgcccatagc gattttgttg tcgcaagctt ccaacaaggc aaaatcattc
     1381 ggaccatcgc caaatccaaa agtaggaact ttttccagct gaagttcttt ttgcagacgt
     1441 ttgacacctg ccccttttga gattcctttc ttcactgtat cgatcgagta aggaccattc
     1501 cgataaaaag ttagctcagg aaaatgttcg tgatagtatt cgtcacctga ttgagataag
     1561 atcagcaaca tatttactgt gttttcttta aagcctaaag gatcaatttc cggaacatct
     1621 gaatgaatga agtcgtaagc attgatcatt gtttggctat gaccggtaca ccagattttc
     1681 tgatcgttat agtaagaaag ttcatgaccg ttcaactgta catgatcata cattttttga
     1741 cattcttctg aagaaaatgt ttgagaatag atttcttcgc cgtctactcg aatgaaagaa
     1801 ccattcatgg tgaccgcaga agtaatgccc gcatcttcca tgatagagtg gatttctgct
     1861 tctgtacgtc ctgtagcgat gacggggaga acattgtttt cttttaatgc gttcatagct
     1921 tttgccactt cgggtgtgat ttttgatttc gcatctagta atgttccatc aagatcaaag
     1981 aaagtgattg cacgataatt tgacacaaat aaaactcctt ttttattgga ataagtttat
     2041 cttaacaaag aatgaacaaa agacaaacct ttcgtgaaga attcctgaac atattggttc
     2101 agtcaacaat ttagagtata ctataagaag agaatttagg agggaaagaa tgattttttt
     2161 cagtattggt atcttattct taataattgg cagtcttttt cggattctgc cctcaaaagg
     2221 aaatctgcct ttttatgggt atcattcgcc tcttgccgca aaaacagacg ctcattggcg
     2281 gctggctcaa aagacaagcg gaaactggtt ttttcttatg ggcttactga tggcattgat
     2341 cggctattat ttaaagacat ctgggcatac gaattatttt ctgattgaaa tgcttctgct
     2401 agtatttcca attatgccta tttttattat gacagaaaag aaattacaga aatatgacct
     2461 ggaaactgga gggaacgata atgaatattt taatgattga agataatcaa tctgtttctg
     2521 aaatgatgca gatgtttttc ttaaatgaag gttgggaagc aactttcaag tatgatggaa
     2581 aagaagggct cgatgccttt ttagaaaacc cacaacattg ggatatgatt acactagacc
     2641 tgaatttgcc cacactggac ggtatgctag taggaagaga gatccgcaaa gtttcaagta
     2701 ctgtgccgat tatcatgctg acagctagag attctgaaag cgatcaggtg atcggcttag
     2761 agatgggggc agatgattat gtcacaaaac ctttcagtcc tctgacgctt attgctcgaa
     2821 tgaaagcttt gcatcgccgt agtgagttgg cagaagcaag agaagaagca gtagtttcag
     2881 atgatcattt tgatatcgag actagtcatt tcaagatgaa tacgaaaaca cgagaagcgt
     2941 atctggacaa ccggccaatt gaaggactga cgcctaaaga gttcgatcta ttgtttactt
     3001 tagcaaaaaa accacgtcaa gtattctctc gggagcagtt gcttgaatta gtctgggatt
     3061 atcagtactt tggtgatgaa cggacagtgg acgcccatat caagaaatta cgacaaaaaa
     3121 tcgaaaaggt cggaccacaa gtcatccaaa ctgtttgggg agtcggctac aaattcgatg
     3181 attctggtgt tgcctaatgc gttatttgta tcagcaactc ttagctttct gcggaatggt
     3241 cgcgttgatc ttattgatcg ttggagtttc ttttacacaa ctgacaaaac aaacgattga
     3301 agaaaacaat taccagcaac tgtttggata tgctgaatca gttgaaaaga caacgcaaac
     3361 ctatgccgat acgctcccgc agtttagtca agatcaggcg tttcaaaatg cattgctgct
     3421 gacagagcaa gtactgacag aacaaaatgt gaactttata tttatcgata aaaacgaacg
     3481 tgtcatttat ccgactaata cagctttact gaattttacc ttaacagctg atcaatggaa
     3541 aaatctgagg aatggacgtc aagaaaaatt cacatcgaat aaaaatattt taggacaagc
     3601 acaggcgacc tcttacgcac ttgtgccatt taatttgaat catgaattct atggagcact
     3661 tgtagttagt caacctgcgc gaaatatcga taacagcgtt cgtccaatta cactgaacct
     3721 gttcaaagga tttatttttt ccagtatcgt tgcagttatt gccagctatg cttttgcagc
     3781 attccaagtt aagcgtatca atcggttaag gaatgcgacg aaagaagtga cgaatggtaa
     3841 ttttgatgta cagctccccg tacatgacaa agatgaattt gatgagttag cagatgattt
     3901 caataaaatg acgaattcat tgaaagaatc tcaagcagaa attgaagaac aagaaaatcg
     3961 tcgaagacaa tttatggcag atgcttctca cgagatgaga acacctctta cgacaatcaa
     4021 cggacttctg gaagggttag aatacaatgc aatccctgaa aatcagcgag aaaacgcgat
     4081 taaattgatg aaaaatgaaa cagagcgtct gatccgtttg gtgaatgaaa acttggatta
     4141 tgaaaaaatc cgtacgaatc aaatcagtat ggtcattaaa aaattcaatg gaacagaaac
     4201 attgaaaaat attgttgcac agttagaagc taaagcagaa gcagcaggag atacattgac
     4261 attgaaagcc gttgatgata ttgatgttta cgctgattat gaccgatttg tccaaatcat
     4321 ggtcaatatt attcaaaacg cgatacagtt tactgaaaac ggccaaatca cgattacttt
     4381 agaaaaaggc tatcttgaaa cgatcatcac gattgaagat acgggaattg gaatgtctga
     4441 acaacaaatg aaaagtatct gggatcgtta ttataaagta gatccttcaa gaaaaaatac
     4501 aaaatatggt gaatcaggat taggtttacc aatcgtgcag caacttgtac gcttgcataa
     4561 aggaaaatta gaagtagaaa gcgaactagg aaaaggaaca aaattcgctg ttcgtttgcc
     4621 tgacgtagaa atcaaaaaag agtaaaaaac aagcggtata aaagatcatg aatcgatctt
     4681 ctataccgct tgtttttact ataaaatgat tgatttagcc cgcgggctct aaacgatcaa
     4741 tataaggact ttgagcaata gtagcatcat gagtaaagag taagatacct tgattttctt
     4801 catgagctaa ataagaaagc aagtggagta gctcttggat ctccaataca ctaagttcat
     4861 caaatgtatc ttcaataaca atattgtttc gcttggaaag caaggcatga agtaattgca
     4921 gctttacttt ttcaaaagac gtcaactcag ctgccgcaca attaagcaag gaaggagaga
     4981 tatcaagttt ttcttgatag gccaaacgat cttgtttgat ttctttttcc ggtacatcca
     5041 acaggacatg gtctttaaga ttcagataag gaaacatcgg ccaatttttt tggatgatcg
     5101 caaaattatc cagttttgca acaagaacct cttttttcaa gtgctccaat attttatgct
     5161 gtttttcgag aggacacaaa ataacggtca agtgttcagc atgaatcaaa tattcaggtt
     5221 tcattacgtc caggcctcct actttgcaaa tgatggataa aaaagtgaaa gggaatagac
     5281 taagaatgag acagcatcca ctgagcccaa taagagtttg ggcaaatccc ttaagtatat
     5341 ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa agtctgttga tccatcggaa
     5401 ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc tggcagttca gtagtcttta
     5461 agacaagaaa attgatcctt tgaagaagcg cttcataaac tgactggaag cttacgatcc
     5521 acaataaaac caagatacaa caaagaaaga gaggaaagaa cagctgccag aaaataaaaa
     5581 ggaataattt ggttttagaa agaccagtca ggtgccaatt gatcaattcc tgcttgtttt
     5641 gcctgactga atagtaaaag aaaaagataa aaaggaaggc aaatagaaaa aataaactga
     5701 atatgccttt tatataaaat cggctagcta attctaaagc cggaagaagc tctgtagatg
     5761 cagaagcgcc aataaatgaa agccgatctt ggacttgatt ggctaaagcc gattgcaaat
     5821 ggtaaagagt caggcatgct atcaataaaa aagcagaaaa gcttgaaaat aaacaataga
     5881 gtattgtctg ctttttgtaa taaattaatc gagcagtagc atagcggatt attttcatac
     5941 ttttcacctc tataaaaagt atagaaaatg aatatgaata aagtatgaaa ttcctttagt
     6001 gaaatcacga attaaaacca gaaaatattt tgtaaaaagc aagaggttgt gaagaagctg
     6061 ccctattcta ttaccgtaga tgcaagcttt tgaacactgt ttattcgaaa agaggagcag
     6121 cgacaataat tttgtcgctg ctccttttaa atttatttta tcattcggaa gaacttgtgg
     6181 tcgttccgtg aagttcttgg tacgtttgcg ttttataaag atcaacagtt gattgtccgt
     6241 tgtgttcact aaagacacta gttgacttgt caccaagaga tttttcagct tcttttaatt
     6301 tctctaagcc attcttgtag tcataatcac tggtatcaat tgggtctaat ccactattcg
     6361 tatagaaccg aagaagatca ccattattga tttggtcaga aacagctaac tgtttatcaa
     6421 ctttttcttt cagtgaatca atttcattct gtacttcctc agtaggttca gtaatagctt
     6481 caccagtttc gttactatag atcgtaccac cgtagtaagt atattttggt gtaacaaaat
     6541 caccatcacg gaaagaaaca agctgttcat gatctttcga gaatagatct tgtcctaact
     6601 gaatataatt ttttgtatct acacctagta agtgaagtaa tgtaggcaag gcatcaactt
     6661 gtccgccgta agtgtgattg attccgccct gtgtttgtcc agggatatgg atcatataag
     6721 ggacacgctg catttgtgca ttgtcgtagt ttgtccaagt agaacttgtt tttccaacta
     6781 attcagctag atttttattt cttgaattcg agacaccgta atggtcaccg taaaggacga
     6841 tgactgaatt atcatacaag ccgctttctt tcaaataatt gaagaattct tgtacggcgg
     6901 tatctaaata attggctgtc gcaaagtaac cgttgatcgt ttcatcattt gtattggcta
     6961 acgggaatcc tgcttcgtca ttggtgaatt ttgaataagg ataatggtta gatacagcaa
     7021 tgaattttga ataaaatggt tgttgcagac gttccaagta ttgtacggat tgttggaaaa
     7081 atggtttatc atgcaacccg tattggaacg aattgtcatc attaacatca taataagaag
     7141 aatcaaagaa ataatcatat cctaaattct tgtatgtctc gtttcgattc cagaatgtac
     7201 cagcgttccc atggaatacc gcactaatgt aaccttgtgt ttgacttaaa atatcaggtg
     7261 cagcttggaa agtatttttt ccgcctaatt gtgtgaacaa ggagccttga ttcaagccaa
     7321 acaatgaatt ttccatcagc gtttccgcat cgcttgtttt tcctgctttt acttgatgga
     7381 aaaagttgtc aaaactgaac gtgctgttgc tgtggtaaag actattgatg aaaggtgtaa
     7441 cttcatgctg gagaccattc tcatctgtca atttataatc gatcaggaat tgctggaagc
     7501 tttctaaatg gatataaatc acattttttc ctctagcgag cccgaacaaa tcgtcatttg
     7561 gtgctgcata atgttctttt acataatttt ctacttcttt catatcattg ggacttgctt
     7621 ctgcccgcac ttggtttgtc tggtaagttt gaacaccgtc ataaaccatg aaagcattca
     7681 agccaagata tttgaccaaa taatcacgag agaatgttcg agtcagcaat tctggacgat
     7741 cagcttccgc cataaaaaga tttcctgaga aaatcataac tgctaatgta gagatcgcaa
     7801 aagccattct tgctcggatc gggcgagggt ccaacttgat tttttttgca atcagcagaa
     7861 cagtcaagat aataaaatcg atccaataga tcacatcata tgggcgaaac agtcgaatgg
     7921 cactttctcc cagaccactc gctactttcc cagcacctaa aatcgtgttg atcgtaatga
     7981 agtccgtgaa ttctcgataa taagtgacat tcgaaaaaac aagcaatgtc aaaagaaaat
     8041 aaatgaccat catcgtgata taagcaactc tagggcgtct gatataaaga gcaattccaa
     8101 gtaataacaa tgtagttgca atagggttga taaacaagat aaagtattga atgccacttt
     8161 cgattccgag atggaaatca actaaatagg caaaaatcgt tttcaaccaa agtaaaacga
     8221 ctagtaaaga aaaaaatccg agcctcttat tcaaaaaggc aggtgttttt atacatttca
     8281 agataatctt cctttctgca cttcttaatc acagaagtgt cctgaaacca tgttacacag
     8341 ctcacttatt ctcatttatt ttactagtat gacaatatag tgtcaattga aaccagaagt
     8401 ttatgctgtt tcattaaggt tttctttaag cttcatgaaa aaatgagcag taagacaagt
     8461 cctatgtttt ttgttatact tgggaagaga aagctaaagc aggtgaagga atgaaagtaa
     8521 aagtaaaaaa aagagcaagc aatcgattga aaaaaggata tccactgatc caaaaagaag
     8581 accttgctca tccccaaaaa gaaaccacgc aatgggtgga attagttgat tcgcaaaacc
     8641 aatttatcgc aaaaggatat ctaggaaagc agaataaggg aatcggttgg gtattgagcc
     8701 agcagaacat cccatttgat caatcttttt ttgaagaatt ttttgtgaag tcaaaagaaa
     8761 aaagaacttt ctttttttca gatgattcta ctaccgcttt tcgtatattc aatggagaag
     8821 gagacgggat cggcggtctg attgttgatt attatgcagg ttatgctgtt ttttcttggt
     8881 ataacgaaac gttatatgca catcgtgaat tattgattca agcttttcgt gaaatctacc
     8941 cggaaatcat aggaggctat gagaaaattc gatttgaatc agtaaatctg cctgagagcc
     9001 agttcattta cggaaaagag gcaccggaac ccttgatcgt aaaagaaaac ggagtaaaat
     9061 ttgccgttta tttaaatgaa ggattaatga ctgggatctt tttagaccaa aaagaagtac
     9121 ggggatcatt agcagaaggt ttcgcttctg ggaaaacagt tttgaacatg tttagttata
     9181 ccggcgcctt ttctgttgct gccgcaatgg gaggggcaat cgaaacaaca agtgtcgatc
     9241 tagcaaaacg cagtttaaaa aaaacacagg aacagtttga agtgaatggt ttggatgtcg
     9301 atcagcaaaa aatcattgtt atggacgtat tcgagtattt caaatacgcc aaaagaaaac
     9361 aatttttata tgacatgatt gtattggatc caccaagttt tgccagaaat aagaaaaaag
     9421 tctttcgcgt agcaaaagat tatggggaac tggtcaagga tagtctggat attttagcag
     9481 aagacgggat acttattgcg tctacaaatg ctgcgaatgt ctcgatagaa caattccaaa
     9541 caatgattga agaggaattc catgccaaaa atgtttcttt tgaacaactt gctttatatc
     9601 gtctgccaaa agatttccag acgacggata cctttttaga aggcaattat ctgaaagtgt
     9661 ttgtttatca aattaaaaat aaccattaga aggagcgatg cagaatggtt cgggtaaagg
     9721 gattgaatat aggaagcggt agaccaaaga tttgtgcgcc tcttatcggg gccgtccgag
     9781 aggaagtatt acgtgaagca gttcttgcac gtgaagcagg ggccgattta gtcgaatggc
     9841 gagtcgatca ttatcgtgaa gttttttctt ttgatgaagt agcagaaaca ttggttctta
     9901 tccatgagat gcttgatgga ctgccgttat tatttacgtt tcgtacctta gctgaaggcg
     9961 gagaacaaga catatcgatc cgtcagtatc gcgaccttta tgaacatgtg atacacacag
    10021 gattagtaga tatggtcgat atcgagttgt tcaaagtaga aagtctagga aaaagactga
    10081 tagaggaaat caagtcttta aacattcctt taattatcag tagtcatgat tttaaagaaa
    10141 caccagcaga ccctgtcttg ctttaccgat tgaatgttat ggaacatttt ggagccgata
    10201 tcggaaaact ggcagtaact cccaataatg aacgagatgt tttgcggttg atggagttga
    10261 ctagacgggc aaatgctttt ttctccatgc ctattattac gatgtccatg ggaaatcttg
    10321 gtaaaatttc tcgtctggtt ggcggaacga cgggttccgt tatgacattt ggttccttaa
    10381 gcagcgattc tacttctgct ccaggacaat taccggtcaa agcattgaag caaattattc
    10441 aattattaaa tgaaccgttg tagaacaagt ttgaggtgat attttttggc aaagaaaaaa
    10501 atagtaaaaa cgaatgcaat ccgtatggtc gaacaaaaaa agattcccta tacagagcac
    10561 gaatatgagt gggacgaaag ccacctaagt gcgtcatcgg tcgctgaaca gcttccagaa
    10621 agccaatctc gtatatttaa aacactggtt gctgtgggca atgtgacggg gcctcttgtt
    10681 gctgtgatac cgggagaagc cgaattgaat ctaaaaaaat tagcaaaagt ttcagggaat
    10741 aaaaaagtag aaatgctcca tttaaaagat ttggaagcaa cgaccggata catacgtggt
    10801 ggctgctcgc ctataggtat gaaaaaacta tttcctactt atttagatca aattgcagaa
    10861 agctatgaac aaatcattgt ctcggctggc agaagagggc tacagatgga gttagcacct
    10921 caagatatct gtgcattaac gagcggacaa tttgcagata taaaacaata aatcatacgt
    10981 ataaaagaaa gaaggaggcc gggatgttgt ttgtccagtc tccttctttc ttttttatac
    11041 attatgctct ttgcccggca ttcattcctg ctacatgccc tgtagcgaaa gccgctgtga
    11101 tattaaagcc gccagtataa ccattgacat ccagtaattc tcccgcaaaa tacagaccat
    11161 caatgatttt actctccaat gttttaggat aaatttcctt tagagaaacc cctccgccag
    11221 ttacaaatga tttctcaata ggaaaagttt tgttgattga tagcttaaac tctttgcata
    11281 gttgaacaaa atcttgaatt tgtttttgag aggcttgttg tcctgtcaga tgatccattt
    11341 caagccgctc aagaaagaaa actaacaatc gctcaggcaa tataccatgc caagcattga
    11401 ccaagttctt tttggttgct ttactttttt ctgtcaatat atgaataagc tcttgtttgg
    11461 tttgtgtagg gaaacaatcc agagaaagtg tcactggttc tcccgttttc tctaattctt
    11521 tattgacaaa acttgaacaa cgcagtgcag ccggaccaga aataccgaaa tgggtgaaaa
    11581 gtaaatccat cgtatgttca gtcaatacac gacctttttt atttaaaacg cgtaaagtga
    11641 tgtcttgtaa agaaagccct tgaagtgttt tctcctgaat atacggttca tccgatatca
    11701 agggggactc tgtcgcataa agaggcgtca ccgtgtgacc cactcgcttc acgatcttgt
    11761 acccatctcc agtagaacca gtagatggat aagtccgtcc accagttgtt aagataatgg
    11821 caggagcatg gaactcttcg aattccgtgc gtataccgta aattttatgt tctttgtgga
    11881 tcaatttctc tactcgagta gagaatagaa gcgtcacatc tagttctttc agacgattga
    11941 gcaatgcttc gataatcgtt tttgatttat ttgttacagg aaacatccgt ccatgatcct
    12001 cttcttttaa atgtacgcct tgtgattcaa agaagttcat gatatcgaaa ttattccatt
    12061 gcgcaaacgt actatataaa aactttccat ttccaggaat atgtgcaatc aaatcatcaa
    12121 caggacgatt gttcgtaaca ttgcaccgac caccacctgt catcagtagt ttttttcctg
    12181 cttttttgtt tttttcgatc aagagtacgc gtgcgccttg ttcagctgca ctgatcgctg
    12241 ccatcatccc gcttgttcca gcgccgacta cgatcacatc atacagtttt tccattccct
    12301 cacctcaagg aaagtgtagc atatctgaag aaagaaaaca gaaaaaaatg ttttgagcca
    12361 aaagagaaaa tgagctaaaa tgagggaaga taagcaaagg agcgtggaac gatgacaaac
    12421 gcaacagaat atgttcaagc aattcaagaa aagctacatc aaaaggatca agggcaagaa
    12481 gaatttttac aagcaatcga tgaattcatg cccacggtta tgtctttttt ggacactcat
    12541 cccgaatata tcgaaaagaa tatcttagaa cttttaacgg aaccagaaag agttattcaa
    12601 tttcgagtgc cttggcaaga tgatgaagga aactggcgag taaatagagg gtaccgtatc
    12661 caatacaact cagctatcgg cccttataaa ggtggattgc gcttccatcc tagtgtcaat
    12721 ctaagtatct tgaaattttt ggcttttgaa cagattttca agaatagttt aaccggtctg
    12781 ccaatcggtg gaggaaaagg cggaagtgac ttcgatccta aaggaaaatc tgataatgag
    12841 atcatgcgtt tttgtcaaag tttcatgctg gaattgtcaa aacatatcgg cccatcgatt
    12901 gatgttcctg cgggagatat cggtgtagga gctagagaaa tcggctattt gttcggcgaa
    12961 tataaacgat tgaaaaaata tgatactggt gtgttgacag gtaaaccttt ggatttttgg
    13021 ggaagtaaga tacgtacgga agctactggt tatggattag tgtattatgt caaacatcta
    13081 ttgaacgaag aaaaagattc atttaatcaa aaaacagttt ttgtttccgg aagcgggaat
    13141 gtagccattt atgcaatcga aaaagtgcaa gagctaggcg ggaaagttgt tacatgttca
    13201 gattctagcg ggtacatcta tgatccagaa ggaatagatg tgaaactatt gaaagaagtc
    13261 aaagaaatca atagacaacg tttgacggaa tacgcaaacc aacgtccttc tgctatttat
    13321 catgctggag aatctgtttg gacattgaaa gaaaaagcgg atatcgcttt gccatgtgct
    13381 actcaaaatg aaatagacga aagcttggcc gaaatcttag tagaaaatgg gatcaaaatc
    13441 gtagcagaag gcgctaatat gccatgtaca gtaaaagctg tttctgttct tcatgaagca
    13501 ggcgtgtggt attgtccagg aaaagctgct aatgctggag gagtagcagt atctgcttta
    13561 gaaatgagtc agaacgtcca gcgattgact tgggaaagag agcaagtgga tgagcagctg
    13621 gatcaaatca tggaaacgat ttaccatacg tgtcgccaaa cagcagccga gtacggcgac
    13681 gaaaaaaatc tgcttcttgg agcaaatgtt gctggatttg aaaaagttgc caaagcaatg
    13741 gcagcagaag gtttagtttg aaaaatgaaa ctttcttgga aatattgtca gcattttgtt
    13801 tatttgcttg aaaaataata aaaaaaaacg taaagtatta cctgtagagt aaacctataa
    13861 ggaggagaac aaatggcaca cattcatttt gactattcaa aagtagcacc gtttgtcaac
    13921 gaacaagagt tagggtacat gcaaagccaa gtaacagcag cccacaacga attacgggaa
    13981 ggtactggcg caggaagcga cttccgcggc tggatcgatt taccaacgaa ctatgacaaa
    14041 gaagaatttg cacgtatcaa agaagcagct aaaaaaatcc aatctgattc tgaagtatta
    14101 gttgttatcg gtatcggtgg ttcttattta ggcgctcgtg cagcgatcga cttcttgaat
    14161 cacacattct tcaatttatt agatagcaac acaagaaaag caccacaaat cttctttgcc
    14221 ggaaattcaa tcagctcaac atatattgct gacttgatcg aagtaatcgg tgatcgcgac
    14281 ttttcagtaa acgttatttc aaaatctgga acaactactg aaccagcgat tgcgttccgt
    14341 gtattcaaag agcttcttgt taagaaatat ggacaagaag aagcaaacaa acgtatctac
    14401 gctacaacag ataaagcaaa aggtgcagtt aaagtagaag cagatgcaga aggttgggaa
    14461 actttcgtga ttcctgatga catcggcgga cgtttctctg tattaactgc tgttggtttg
    14521 ttaccaatcg ctgttagtgg tgcagatatc gatgcattga tgcaaggtgc cgctgatgca
    14581 agcaaagcat actcaagcga caaactagaa gaaaacgaag cttaccaata cgcagcaatg
    14641 cgcaacattc tttaccgtaa aggcaaagta actgagttgt tgatcaacta tgaaccagga
    14701 atgcaatact tctcagaatg gtggaaacaa ttgtatggtg aatctgaagg aaaagaccaa
    14761 aaaggcatct atccttcaag cgcaaacttc tcaactgatt tgcactcttt aggacaattc
    14821 atccaagaag gacgtcgcaa tatttttgaa acagttgtga aggttgaaaa acctcgtaaa
    14881 tcaatcacaa ttcctgaaca agcagaagat ttagacggtc taggctactt gcaaggaaaa
    14941 gaagtggact tcgtaaatac aaaagcattt gaaggaacat tgcttgctca tacagacggt
    15001 gacgtgccta acttgctagt caaaattcca gaaatggatg cttatacatt gggttataca
    15061 atgtacttct ttgaaattgc tgtaggtatt tcaggttact tgaatggaat caacccattc
    15121 gaccaaccag gtgtagaagc ttacaagaaa aacatgttcg cacttctagg caaaccaggc
    15181 tttgaagatc ttgctaaaga attgaacgaa cgcctgtaag ataagggttt ttcgctagat
    15241 ttaaataatc agtgatagaa acatgttcgc tttaaaatga aaactggtac ccatttaggt
    15301 actcaaacat actgcatcgt ttattcagaa taaggggctg tgacaagacg tttgtcacag
    15361 tcccttgttt gtatagaaat cgattgattg ccttgctctt tagtttgttt taggacttta
    15421 agaacagtga ggctgacttc gaaggttaat tctgtttttt tgttttctag aatcagtaag
    15481 caaaaaagca ctcacttcga gtgctttttt gcgatatatt cttagcttaa gataggccta
    15541 atttttcttt tacagatgag ggtaccttat cgctggtaat tacttttttc tctatgatcc
    15601 gcttttcgct tgctttcaac tgcaagatcg ttccttcggg gtaagcagaa ccattggcag
    15661 agtcaccaga agtaatgaca tcgaaatcta actgtctttt ttcaccgttt tcagcataag
    15721 catctacgtt gtatttaaaa cctcttccaa ttacttcccc attatctgct ttgatatcag
    15781 tttctgcagg cattggagct ttgactaccg cataataatc tttacctaca taagtagact
    15841 gatagtagtc ccaacctttc catcctataa aagcaatcaa tatgataacg atcaacccta
    15901 aaattttttt catgaaagat ctcctttttt attttta
//
LOCUS       DAXLPQ010000055        15134 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.055, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000055 DAXLPQ010000000
VERSION     DAXLPQ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.055"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(26..319)
                     /locus_tag="ACF3UO_002183"
     CDS             complement(26..319)
                     /locus_tag="ACF3UO_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFD3658142.1"
                     /translation="MELTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(347..1012)
                     /locus_tag="ACF3UO_002184"
     CDS             complement(347..1012)
                     /locus_tag="ACF3UO_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFD3658143.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1152..1784)
                     /locus_tag="ACF3UO_002185"
     CDS             complement(1152..1784)
                     /locus_tag="ACF3UO_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3658144.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDCPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1791..2858)
                     /gene="liaS"
                     /locus_tag="ACF3UO_002186"
     CDS             complement(1791..2858)
                     /gene="liaS"
                     /locus_tag="ACF3UO_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFD3658145.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEIAKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2855..3586)
                     /gene="liaF"
                     /locus_tag="ACF3UO_002187"
     CDS             complement(2855..3586)
                     /gene="liaF"
                     /locus_tag="ACF3UO_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFD3658146.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACF3UO_002188"
     CDS             complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACF3UO_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFD3658147.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACF3UO_002189"
     CDS             complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACF3UO_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFD3658148.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPNGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEKAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            5709..6869
                     /locus_tag="ACF3UO_002190"
     CDS             5709..6869
                     /locus_tag="ACF3UO_002190"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFD3658149.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(6909..7856)
                     /locus_tag="ACF3UO_002191"
     CDS             complement(6909..7856)
                     /locus_tag="ACF3UO_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFD3658150.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDME
                     KQVTFIEGDVSDPQLMERIMKQYQFAYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFASEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(7989..9380)
                     /locus_tag="ACF3UO_002192"
     CDS             complement(7989..9380)
                     /locus_tag="ACF3UO_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFD3658151.1"
                     /translation="MLNEKFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFAINIFIQFS
                     FIALSGSRTTLVCLLIATFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAQAWAHVPHITEIKKDISDSSGTTSSNKVDLKRPDTDGGDVSNLRFGLWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKTLRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            9506..9916
                     /gene="tagD"
                     /locus_tag="ACF3UO_002193"
     CDS             9506..9916
                     /gene="tagD"
                     /locus_tag="ACF3UO_002193"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0047348 - glycerol-3-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HFD3658152.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGQFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            10330..11130
                     /locus_tag="ACF3UO_002194"
     CDS             10330..11130
                     /locus_tag="ACF3UO_002194"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3658153.1"
                     /translation="MRLRKQHYHYQSCGKYFTAHTYLVVPSCFISKQVHYTILEELTE
                     RQALKTLTKRCDLSVTTFQRTLSALSAMLRQMLDYLPHCLLFDEFRSLSISHGKFSFS
                     CMNRETGKLFDILSSRRKKDLIAYFMRFTRKAHMGVRYIVTNMNAPYFSLVKESFPNA
                     QIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKDTSQAKYYRQLKPLYKLLLKSDDELDY
                     TTFKKWQNFQWRYLTESEVVDRLPSISYELKIAKQFIKSCLAIITRNS"
     gene            11239..11385
                     /locus_tag="ACF3UO_002195"
     CDS             11239..11385
                     /locus_tag="ACF3UO_002195"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658154.1"
                     /translation="MTKLENLRTHIKTLKRFAYGFRSFTNMRLWIFLINRLISYALKA
                     SNSY"
     gene            complement(11452..12879)
                     /locus_tag="ACF3UO_002196"
     CDS             complement(11452..12879)
                     /locus_tag="ACF3UO_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3658155.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFIQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIVGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIIIFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPIFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTELSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVILFFIVNLTLTTWAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEIRKITRK"
     gene            complement(12876..14018)
                     /locus_tag="ACF3UO_002197"
     CDS             complement(12876..14018)
                     /locus_tag="ACF3UO_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HFD3658156.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQLYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSKK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNFMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELIERDIK"
     gene            complement(14022..15017)
                     /locus_tag="ACF3UO_002198"
     CDS             complement(14022..15017)
                     /locus_tag="ACF3UO_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3658157.1"
                     /translation="MHKISVIVPAYNVEDYLENCLESISNQTHSNIEIIVVNDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILIFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
BASE COUNT         4936 a         2875 c         2210 g         5113 t
ORIGIN      
        1 aaaacttgtg tcaccctctc tttttttatt gttttttaaa gtgataggtt ggctcctcca
       61 ggttgggatc ataatcaaca agtaaatcat atcctttaaa gaaccattca tctgcttcct
      121 cgataaaaaa aagtgtccca tccatttcca ctttctttac aggatgttct ggctgttcaa
      181 ctgacattcc aatcgaaaaa ccatcatgaa cctctgtttt gccgtagact tttccaaaaa
      241 aacgtattcc gtaagtttct ggcagatcaa tttctgagtc aaaccacttt tgtgcttttg
      301 gcgttaccgt taattccatc ccaacaacct actttctctt ttctttctat tgattcatct
      361 tatcgtctag aatatccaca tcgcctgtct ctccaatcac cagtagatta tcattttcgc
      421 gaacatattc atctgctgca ggagaagcga taaccgtttg atctactctt cgtatggcga
      481 ctactgttaa gtcaaaacgt tgcctgaaat ttaattcagc taatgttttg ttgaaaaatt
      541 taggattgga gactcggatt tctgctaaag aatatttatc tgacagctct aagtagtcta
      601 gaatattctt tgatactaag ttatgtgcaa tccgtatccc catgtctcgc tcagggtgta
      661 cgacacgatc tgctccgatc ttctctagta cacgggcatg gtactcattt tgggcttttg
      721 ctaaaatatt cggtacgccc atttccttta ccatcagagt aactaagata ctggcttgga
      781 tatcttctcc aatagcgaca attacatgat cgaaatttct tatacctaat gaacgaagtg
      841 tcatctcatc ctgtgcattt gccacaacag catgagtggc tatattcata tattcattga
      901 ctcgatcttc attactgtca atagccagta cttcttgtcc agcttcgatc agtgtacggc
      961 agatgcttcc gccaaatcgt ccaaggccta caattgcaaa attttgtttc accattttcc
     1021 tcctttagta tcttcttttc tcagtataac aaagcctttc caaaaacaaa agcaagcatc
     1081 attattgtaa aaaagccaag aaaaataata gttattttct cagcttttga ttatcctctt
     1141 tatcatcgtt tttatttcac caaaccatgt ttaaacgcat agatagctgc ttgagttcgg
     1201 tcttctacct ctaacttagc taatatattc gacacatgcg ttttaactgt tttcagtgtg
     1261 ataaacaatt catccgcgat ttcctgatta cttttccctt cagaaatcag catcaaaatt
     1321 tcattttctc gattcgttaa ttcttcatgc aatactggat catttcgccg actcattttt
     1381 tccatcattt ttgttgtcac ttcaggttcc aatactcgct cgccgcgttg cgtagccctt
     1441 atagcatcag ctatttcatg tgcggtagac gtcttcaaca aatatcctgc tgctcctgct
     1501 tcaattgcag gataaacttt ttcatcatca ataaaacttg tgacgataat gattttggct
     1561 tttggacaat cttttaagat tgcttttgtt gattcgatgc catccatttc ttccatgact
     1621 agatccatta aaatgacatc tggtcgaagt gccatcgcct tttcatagcc ttgacgtcca
     1681 ttttcagctt ctccaatcac ttcaatgtct tcttggatag ataaataaga agagacgcct
     1741 aagcgtacca tttcatggtc atctactaat aaaactttta tcatctttat ctatgcctcc
     1801 ttcatcaaag ggaccttgat ctccacgctc gtaccttgcc ctttaaaact aatgattttt
     1861 actgttccac caataccagc tactcgttct ttgatattgt tcaatccata acttcccgtt
     1921 ttggtttcat tcatattaaa tcctgtcccg tcgtcaatga tacgtaataa aagattgtta
     1981 tctattttat gcaaatagac ttctaattca ttagccttag catgtcttaa tgtgtttgat
     2041 aacaattctt gaacgattcg gaacaagtga tcctcaatgg aactagttaa ttttacatct
     2101 tctacatccc attttagcga aatctggatt ttattctgca attccttcaa taactgctca
     2161 atgccttgtt ttaaactttt ttcttctaaa ttgactggac gcagatgaag aagcagcgca
     2221 cgcatctcag actgggaagc gttgatgatc tctgccacca ttttcaactg cttacggaac
     2281 atttctggtg tctcactttt ttctgcttgc tccgtcaatg ccgacatcat catcatcgct
     2341 gcaaataatt gctgtgaaac tgaatcatga agctcacgag ctaatcgatg cctttctaat
     2401 tctaaaatct cttctttggt ttgtccatct acatattgag gacggctagt cataatctgt
     2461 aattcactgg atacttcgat cattttttct tttattttag caatttccat atcaatatct
     2521 ttgatgtaca gatcatccga cgcgcttggg atcggctgat gcaaaagttt ggattcataa
     2581 ttgccagaag aaagtgcacg aagcttttct tcgattttcc cgtattttgc cttttgaata
     2641 agtgataaca atagaaatac gatcaatcct acacctaatg aaattgccat caaatggaag
     2701 ataagcggaa cgtataataa acgcgcacgc agcaattctc cccaccaatg actttggtta
     2761 ctggcataaa aataagtgaa aagtgaaaat agaataataa ggaaagccgc aatccccgaa
     2821 taaacagcta gcattgcttt ggatattctt cccatcatat tcgtatcacc tcgacatctc
     2881 caaccaaggt attggtaatg atcttcaatc tgcgaggatt ttcatcataa tcactgctgc
     2941 agattttgat ctgttcgttt tttaaggaaa actgctcttc ttcaaacaag acatttccta
     3001 ctaatgtcgc atgctctaaa cgaatagcca ctcccagggg tactaagatc cgtgttctgc
     3061 ctatcccttt tcttacaatc acaatattat catcttttgg caaaagtgta ttacccaaat
     3121 cgatgatagt atcaccagaa atgatggcaa tgttgatatc atcccattca tagacgtcgt
     3181 ttccaatacg ttggttacca aataattgct gtcttttacg ctcattatta tgtgttttta
     3241 attgctctgt ttggaccatc atgatctgtt tttttcgcca aaaagcattt tttgtcaaat
     3301 ctattcctga aatctctaca cctttcagcc cgataaataa aacggccaat acaaccatca
     3361 tccataaagc aggactgttg actaagctaa aaaaaatgac caagctccct aagatcaatt
     3421 gaaaattttg aaatttagta cgaggatatt tgcgcatagc tagatatata ttgaaaatac
     3481 cgaatattac taaaagcaaa agtccagtat tgtttacgat ttgccaaaca gcaaataaca
     3541 gcagcagtgc ttcgactacc acaaaaaaac gccaagaact attcatcgct ttttctccct
     3601 cctgacacat tctcatttca tcatacctat ttttttgact gttggctata ggactttaga
     3661 tgtaagatcg ttcagtgaaa cctgcaatac tcaaagagaa aagatctaga gtgcgtcatc
     3721 agtaagatga actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt
     3781 aactaacata tcgccacctg gtgtagcaat ggttacttca tcatttttac gtttgccaat
     3841 caatgcttgc gcgataggag aatcattgga aatctttcca gaaaacgggt ctgcttcagc
     3901 acttccgaca atcgtgtact cttcttcatc tccatcaggc aactcgatga acgtaactgt
     3961 tttaccgatc gatacctcat ctgcatctac gccgtcatta tcgatgattt gtgcaaaacg
     4021 gatcatattt tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttagctga
     4081 ttcgtattcg gagttttcgg aaagatctcc gaaaccgcga gcgattttga ttcgttcaat
     4141 gatttctccg cgtttaactg tttttagttc ttctaattct ttttctaatt tttctttacc
     4201 ttctagagtc attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa
     4261 taccgcaaaa ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttctta
     4321 aaatgtaaat gtttttctaa aaatgatcaa tgactagccc ctgtttttct aagaattatt
     4381 tacatatttt tgcactagtt ccatatgttc ttcatacgtt ttagcgaaat aaacatttcc
     4441 agtgctcgta tctgctacga aataataata gtcattttct gctggttcta atactgcctt
     4501 gattgccttt tcgcttggat tgtcaaaagg accaggccca tagccggtat tggtatacaa
     4561 attgtatggt gaatctacag ctgtatcttc atacgtcacc aattctttat gttctcctaa
     4621 tgcatataaa acagagatat ctgactgaag tggcatattt gccttgattc ggttaaagaa
     4681 gacttgtgca atatttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc
     4741 caaagttaaa acttcttgta cagtcaaatt tttctgtttg atagctgaat aatagttttg
     4801 catgaccgta tttgtcttgt tcaccatctc aatcacaaga tccttaagcg aagtactcgt
     4861 gtagtaatca taagtagctg ggaataagta gccttccaaa cggtattttg tgttctcagc
     4921 tttagaggca ctttccaaca attctgggaa tttttgatac aactcgttaa agaaagtctc
     4981 atcatttact aaatctaaaa attctttctt gtctttacct gttaccttcg ctacccgctc
     5041 agcaatctga tcgatgtcgt agccttctgg aatggcaatt ttcccatctg caacttttgt
     5101 tggctcagat gtgccgcctt cttgcaactg cttgccaatc tcatcaagag tcatattagg
     5161 cgctaactga taataaccag cttgaaagcc agttaagttt ttaaattttg tataataatt
     5221 gaaaacaatc ccacttttaa taatattgtc tttctccaaa atttcgccaa tctgcttatt
     5281 agaagagccg tttgggattt ccacttggac taattggtcg tccgatttat ctaaaggctt
     5341 caacccgcta tctacataac gatatacggt aaacccgaga aatccgccaa taatcaataa
     5401 tgtaagagcg atcactaaaa tgatcttcct cacgatctta tcttcttttt tacgcagatt
     5461 tctccgcttg tcgattatat ctgctgtagc tgccttactg gcttcttttt tgtctttgct
     5521 tgggtgttgt ttgtttcctg acaaaacaac tcctccttac tatcatcttc gtaactctgt
     5581 ttattataca tgaaatttct actgccgtga attattttac caaatattat gtcaaaattg
     5641 taagtggcaa atgctctttt tgaggattac aatgaaaaat agttaaaaat ggatagaaag
     5701 gatttaatat ggcaaaagga aaacatcaaa aaaaacagca gatctctctt tcttttctcg
     5761 cagttttgtt gctggctgtc agcttctttt caacaggcat cattacagga tggcaattaa
     5821 caaaacaacc tcaaccacaa atttataaaa cggaacccgc acaacttgct tccaatttaa
     5881 catctaatga gcagatgctt gccagcaaaa ttgatcaatt actgcaaaaa tcagattata
     5941 tcggttcgat ttatgtacgc aaaaataatc gagtgatatt agaaaaagga tatgggtacg
     6001 caaatctacg cataaaagaa tcgaattctc cttctcttta ctatcaaatc ggttcgatcc
     6061 aaaaagcgat gactgcttta cttatcctaa aacaaattca atctggcaag ataacttttg
     6121 acacaaagct atctgaattt tatcctcaga ttcctggaag tcagcaaatc tcaatcaaaa
     6181 atatgcttta catgcgctct ggtcttcatc gaaccgcttc tccaaaaaaa cctatgtcag
     6241 atagtgagat cattcagttt gcccttcatc atttgaaatt tactggttat gatacgtatc
     6301 attatgaacc attaaattat acattgctta caggggtatt gatcaaacta atgaatcagc
     6361 cttatgaaac tcttttaaaa aaagaaatca ttcggccact ccatctagaa catacagatt
     6421 tttatgaaaa tgtaaaaaat tcccctcagc atgctgtatc ttaccaaatg tctgcaactg
     6481 acgattattc aaaagcattg gtcgagcctg aaacagacat ccgaaatgaa ttaggcacag
     6541 gaaatataag tatgtctgtt tatgacttga acaaattctt taccagtgtt ctgtctggcg
     6601 atattatacc aaaagaacta cttttctcat tgtggcaaaa taatggtgat aaacatcctt
     6661 acagcggcgg tgtttacagt ggaaatgatt atatccttgc tcagggaaat atcaatcgat
     6721 tccatgcagt agcggcgatg aaaaaagaca caaaagatgc aatcgtcatg gaaagtaata
     6781 tccaatctga taaaaacatc aaattgccgg ccactgattt aagaaatcag atttacgaac
     6841 tgatggaagg tgttaattta aaaagctaag tcgagacaaa aaaaccagca ggatgctggt
     6901 tttttgtttc aatcgatttc tgtctttaaa taacgttcca ttccgttcaa tatatcaaat
     6961 ttgggttgat aacctaaaga acggatcttt gaaatatccg ctaaagaatc acgaatatcc
     7021 cctgaacgct ccgcttcata tttaagcgct agctctgttc ctaagatttg atcaattgaa
     7081 tgaatcaatt caagtagcgt agtgcttttt cctgtaccga cattgaattg ctgtcctaaa
     7141 gctttttctt ccttagcaac aagtaaaagt gcttgtataa catcttctat ataaacgaag
     7201 tctctagatt ggctaccatc accaaataaa gtaaattctg ttttttctcc tgccaattgt
     7261 tttttgtatc ggtccactag aatcgaaata actccgctat atggagagtt aggattttga
     7321 tttggaccat aaacgttaaa aaatcggaca gcactagtcg gaacatcata taaatgacag
     7381 taatccaaaa catattgttc tgatgcaaac ttatcgatgg catatggtgt taaaggacgg
     7441 atgaccgatt cttctttttt tggcaacgtt ggttcatcgc cataaactgc agctgatgaa
     7501 ctaaatacca atcgttttaa accagattga tattttcgta ccaattcaag caataaaagc
     7561 gcactgtcaa aatttacacg atgagtttct agaggacgtt ctacagaatc tgccacacta
     7621 gctacagcag ctaaatgaaa aatataggca aactgatact gtttcatgat tctttccatc
     7681 aattgaggat ctgatacatc cccctcaatg aaagtcactt gtttctccat atccaagttt
     7741 tctttttttc ccattgataa atcgtcgact actacgattt tgttttcttt tcccaaataa
     7801 ttcgctagcg ttgaaccgat aaaaccagct ccaccagtaa tcaatatagt atccatcaaa
     7861 ttcactccaa ttatgcattc tcatacttaa taaagttagt ttaccatttt tatattgtaa
     7921 aaactataaa atttgttgaa gttgggataa ctagttttct tttctacttt atatacctaa
     7981 aaatagtttc aattagttac tccttcttct ttagatatag ttttttggat agaacccaga
     8041 tatccccaaa aaataaatga acctatcgta ctaaccaaaa tgagttctgt gataaataat
     8101 gccgaaactg ctattgtaag aatcattaaa atagcaaaaa agtgcttatc ttttactaga
     8161 tttggttgtg tgaaacaata acgcaaagtt ttaaagcatt ggataaataa gaaggttaac
     8221 aatgtcaata gacctaatcc tcctgtagca gccataacta agaaaataaa attatgagca
     8281 gttaaagtat cttttcccat taatgtatat ggtagtttat catgtgcgta ttcaatatag
     8341 tatcctggag aaccgccgga tatcggctta ctcttgaata tttcaattgc acttttccaa
     8401 agtccaaacc ttaaattaga aacatccccg ccatcagtgt cagggcgttt taaatcaact
     8461 ttattgctgc tagttgttcc tgatgaatca gatatatctt tttttatttc tgtaatatgc
     8521 ggaacatgtg cccatgcttg agcagttata tctgttacat aatacatcgc aattatactt
     8581 agcaatccta ctactaatgc agttagccat ctttttaaag tattagtttt aagaaaacga
     8641 ctactataac ttgtaaagaa actaaaaaca aaagttgcta ttaataaaca aactaatgtg
     8701 gtgcgtgagc ccgataaagc aataaacgag aattgaataa aaatattaat tgcaaaaaat
     8761 attttaaata gaagatttaa atgcttgtaa gtgaccaaat aatatatagc aataatgatg
     8821 acaattaatg atataaccgc accaaaattt ggatctgtat atacaccaaa taaacggttg
     8881 cctaaccacc ctaaacgaac tgggtaatac ttatatttta ttggaatttt tatgccatat
     8941 tgaatgacaa accagtataa tgatactaaa ttagctaaaa accataccaa tgaaagtatc
     9001 caagtaaata ctttgaaaaa aaagttacta ctgtagtctt tgccaaactg ataaatcata
     9061 aagaaaaaga ttaattgcca catgattaac ttgatatttt cgctatatcc atattttaaa
     9121 ttcattaaac tgcttactag catcgcgcca ataaaagcaa ttaatagcca atcatatttt
     9181 ttaagatttt tttctctaaa tgcaataatt gcatctataa tgatcaagac aactcccgct
     9241 attccagcag gccaaaaaag taaagtatca tatctagtag gtaatagtaa atacgggcct
     9301 attgctcgta acattagaat aaaaccaaaa taaataaaat accaaccttt cacatatttt
     9361 aaaaattttt cattcaacat ttttcctcca tccacctatt tctcataaac atttcttatc
     9421 ctttttagga taaactggtt ctttcaattc taacaaaaaa atgctaaact aacaatgtat
     9481 attaatgaat ttcgagaggt gaaagatgaa aagagtaatt acttacggta cctttgattt
     9541 gcttcactac gggcatatca atttactgaa acgagcaaaa caatatggag attatcttat
     9601 tgttgccctt tctacagatg aattcaattg gaatgcgaaa caaaaaaaat gttattttag
     9661 ttatgaaaaa agaaaacagt tacttgaagc tattcgctac gttgatttag ttattcctga
     9721 agaaaattgg gaacaaaaag taaaagatat aaaagaatac catgcagatt atttcgtgat
     9781 gggcgatgat tgggctggac aatttgatga acttgaacaa ctaacagatg cacaagtaat
     9841 ttatttacca agaacacctg agatctctac aactcaaata aagaacgaac ttaattcttt
     9901 aaatagtgat aaataatatt ttttaaacaa tgaaagaaca atatatctgg ataagacgta
     9961 aaaaaatggc tctataattt ctaggactga tagaattttc tgtcgatcct agattttctt
    10021 gtaaaaaaaa cagacataca aaaatttcga taaaatagag tcgtctaaaa catcaatctg
    10081 aaaggaagat tttgtatatc catttctcgt tctatcaaag agcacttcac tattaaagat
    10141 aaaaatattg aaattaattc ttttcaaaaa actttttata aggacaagaa agccatcgta
    10201 atcgaaggta cattagttcg cacttttaga cattgtctat tttgtaaaga aactgcgaag
    10261 cagctcgtga aaaacggcaa gaagatttca atgattatct taaatcgcag tgggaataaa
    10321 taaacctatt tgcgtcttag aaaacaacat taccactacc aatcatgcgg aaaatatttt
    10381 actgctcata cgtatcttgt cgttccttca tgttttattt cgaaacaagt tcattacacg
    10441 atattagaag agttgaccga gcgtcaagcg ttaaagacac ttacgaaacg ttgtgatctt
    10501 tcagtaacga catttcaacg gacattatct gctctatcgg caatgctgcg acagatgcta
    10561 gactatttac ctcattgttt actattcgac gagtttcgct ctctttcaat ttcccatgga
    10621 aagttctcct tttcttgtat gaatagagag acagggaagc tctttgacat tttgtccagc
    10681 cggagaaaaa aagatttgat tgcttatttc atgcgtttta caagaaaagc tcatatgggg
    10741 gttcgataca ttgtcacaaa tatgaatgcc ccttattttt cattagtcaa agagtccttt
    10801 ccaaacgccc aaatcatcat tgattgcttt cacattggac aacacttgaa caagtttttc
    10861 gatcgtgttc gaaaacgtgt gatgaagcag ttgaatcaaa aagacacttc acaagctaag
    10921 tactatcgac aattgaaacc tttgtataaa ttacttctaa aatcagatga cgagttggat
    10981 tacacaacat tcaagaaatg gcagaatttt caatggcgct atttaacaga aagtgaagta
    11041 gttgatcgtc taccctcaat ctcttatgaa cttaaaattg ctaagcagtt tatcaaaagc
    11101 tgcttagcaa ttatcacaag aaacagctag ctacttcgag aaacgaccaa agaagttccc
    11161 tcgaaacttc actatctcaa aaagcctttt tcatatctga aaaaggcttt taactagcat
    11221 tttcgaaaaa gtattctaat aacaaaatta gagaatcttc gcacacatat caaaacattg
    11281 aaacgatttg cttatgggtt tcgcagtttt accaatatgc gcttgtggat ttttctaatc
    11341 aacaggttaa tcagctatgc attaaaagct agtaactctt actaactttg ttgttcataa
    11401 atgaccttat cagcccgatt tgacaaagaa ctactttttt acaacattat tttattttcg
    11461 agtaatcttt cttatttcat ttcgtatatc tggaaaaaga aaataaacaa acggaagata
    11521 aataatgaaa atcattattg atttaattgc catatctaaa aatgaagaag agaataattg
    11581 tggaagaaag taataggccc aagtagtcaa agtaagattg actataaaaa ataagataac
    11641 gttcttccca aagaaatagg atatttttat ttcttttcgt acaaaaaata ctctaaagaa
    11701 aaagactaat aattctacta ccacgagtac gatcgtagcc gctacagcgc cataagtagg
    11761 cacaaaagct acatttccaa taatacttac aatcgcacca atgatcattg gataagcata
    11821 ctccttatct ttttctatag caattgcaaa ttggttagca aaaactccac caattggact
    11881 aacaactata attagacaag aaataagcat gtttattgtc atcggtttga aattctcccc
    11941 aaaaaaccat ggaacaaatt cttttgtatt gataaacacc acactaaaaa gaattaatgc
    12001 aatgataatc gtgtaatcaa aagatttttt tgtgtaaact aaaatatttt ctgatttccc
    12061 ctctgcctgt gctttagata ttttaggcaa cataacaata gtaattgatg ttaagactgc
    12121 caatataata cgagcaattt tttgagactg atcataataa gataattccg ttggatccac
    12181 aaaataccca actatcgttt tgtctaaagt tgtgtacact tgcataaaca actgaggagt
    12241 caaaataata aaagctggtt tccacaactg tttaaaaaca ttagagttaa agattggttt
    12301 acctactttt ccgtggatac ttaaccagaa aactaaactt cctaaaaagt tagtaattga
    12361 agtaatgaac acgtaaatcc acaaatcatc tttagttgaa acaaaaatga ttattaacaa
    12421 taccgatgat aatttgataa ctgtatttct aataaccact ttcgaaaatt cttcaattcc
    12481 ttgaaaaaac caagaaatat ctaatgttag ccctacaata aatatcaatt gaattaagta
    12541 taaattttta tactttacat caaaaaaata aatataggct atatagagaa aggaaacact
    12601 caagcctatt aaaaattgaa taaagtaaat attccagaat tgtaaagata gtgctttttt
    12661 atctttcctt gatttagcga tatttcgaat acgaaaagga ttcattccca cagcaatgac
    12721 agtcattaaa aactgtgata ttgagaaaac atacccataa atccctaaac cagttgaacc
    12781 aattctacga ctaagtatag gtatagtaag taagggtaaa acaatcaaaa agacttgata
    12841 tatcgcatta taaaatatat cttttactgt ttttttcact ttatatccct ctctatcaac
    12901 tcaagaacct tttctgtact tgctcctgtt tcataatttc caatataatc aagtaactct
    12961 tgagaacttt tcaaaagctt ttcttgttgg tttttaaaaa catcaacaag gccataacta
    13021 tcttgtacgc ttataattgg taactcactt aactgtatat aaaaacctct ttctaagcta
    13081 tattcttttt catcatagtt aaaaagaata attggttttt ttgttagcgc aaaatcgaaa
    13141 aaaatagatg aataatctgt gattaaaaca tctatctctt caaaaagcat ttcaagagga
    13201 atcccatcat taattaaagt aatttgatgt tttttcatat attctatact tttagaatca
    13261 gttgctaatt tactatgaac attaggatga aatttagtca taaaatttaa ttcttgttgt
    13321 tgctttttaa aaaattcacg taagttatcc acacctaacc attctagttg cgtaattccg
    13381 ttgtcctcaa tattatttcg aaaagttgga gcaaataaga cattgatttg tttctttttc
    13441 aagtcaaaca cttgctcttt actagaggct aattcatcgt ttctaggagt tcctacttct
    13501 aatattttag aaggaacgat attgaatgct gaaacatact tcttagaact atagcgatta
    13561 ccagataata aatatgtaat tgactcacta tcttttttcg catagcttag gtaacgttta
    13621 ggtaacttat cttttgcatc aaattcaatt ttttttaaag gcgttccgtg ccatgtttga
    13681 aaataaagtt gttttttcct ttttgcatac ttaatcgttt tccgactatc gtctatccaa
    13741 tacttagctg tatataaata aaaggcagct aaaaaagaat cggagtcaat tcttttaata
    13801 taatctggta aatcagttat aatcgcttct tttttgatta accaaataat tctgtaattc
    13861 aatttttttt catgaatttt ctctgaaata actcttggat ttccagaata gttacgcccg
    13921 ccaaaacttg aaaatacaat taaatttttt tgaataggta atattttaat aaaaaccggg
    13981 aaaatattcc ttgaaaaaaa tttttttata ttcttcatct cttacctcac agattctatc
    14041 ttaatcaaga atttacttgc tatcttacta cttgacatat agtaaggcaa gtttttattt
    14101 attaataaaa actttactaa tttttttaat tttggtgaaa agtcgggatc aattttcact
    14161 tctttttcaa agcgttgtaa aatatttata gaacgtaaat aatcttcttt attggtatag
    14221 ttatttttaa tcattgtcat catcatcctt attgcttcat agacatagcg agttctaaca
    14281 ttaattgata attccggata aaacttatct atgaatatta gtatatcttc atggacttca
    14341 aaagaatcaa aaattctagg attgaagctt cctctcagta tacttttagg gctttggtaa
    14401 tagtgatatt tagcagatga attgacagca actttttcgg aatgatcgat cagcaaataa
    14461 gtagtagcct tatcttccat taatttaccc agtgggaatc ttatattatc aaataaattt
    14521 ctattgaata atttattatt tgcagaatag ccaattttat tatttataaa taagtttttc
    14581 attgcttgtt ctctatcaaa tatttcccat tttctctcag caattgtatg ttcttttagt
    14641 tgttctaaac ttgaaatctt ttttattttt agcaccgaga tatctgctcc ataagtttgc
    14701 gtgccaaaat atagtaactc aagatagtct ggttctatcc aatcatcgct gtcaataaag
    14761 cacacaaaat ctcctgttgc agaatcaaga ccagaattcc tagccgcact taaaccacca
    14821 ttcacttgat gtatcacttt taatcgcata tctttctttt tatattcttc tgcaatttcc
    14881 ccacttcgat ccggggaacc atcattgact actattattt caatatttga atgtgtctgg
    14941 ttggaaatag attctaagca gttttctaaa tagtcttcta cgttatatgc gggtactata
    15001 acactaattt tatgcactct cttcacttcc taaaaatcat cttttttatt tttacaaatg
    15061 tatcattacc agtaacaatt ttagtcttcc gaagttaata aacataaaaa ataacatatc
    15121 gaaaaaaact ttat
//
LOCUS       DAXLPQ010000056        14118 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.056, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000056 DAXLPQ010000000
VERSION     DAXLPQ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.056"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..556)
                     /locus_tag="ACF3UO_002199"
     CDS             complement(<1..556)
                     /locus_tag="ACF3UO_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HFD3658158.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="ACF3UO_002200"
     CDS             complement(572..1051)
                     /locus_tag="ACF3UO_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFD3658159.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="ACF3UO_002201"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="ACF3UO_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="ACF3UO_002202"
     CDS             complement(2098..3204)
                     /locus_tag="ACF3UO_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3658160.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3UO_002203"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3UO_002203"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFD3658161.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3UO_002204"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3UO_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFD3658162.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3UO_002205"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3UO_002205"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFD3658163.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="ACF3UO_002206"
     CDS             8175..8873
                     /locus_tag="ACF3UO_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFD3658164.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="ACF3UO_002207"
     CDS             complement(9041..11680)
                     /locus_tag="ACF3UO_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3658165.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3UO_002208"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3UO_002208"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFD3658166.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14118
                     /locus_tag="ACF3UO_002209"
     CDS             13523..>14118
                     /locus_tag="ACF3UO_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658167.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2543 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagc
//
LOCUS       DAXLPQ010000057        13947 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.057, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000057 DAXLPQ010000000
VERSION     DAXLPQ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.057"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            136..309
                     /locus_tag="ACF3UO_002210"
     CDS             136..309
                     /locus_tag="ACF3UO_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658168.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="ACF3UO_002211"
     CDS             949..1422
                     /locus_tag="ACF3UO_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFD3658169.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="ACF3UO_002212"
     CDS             1431..1658
                     /locus_tag="ACF3UO_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658170.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="ACF3UO_002213"
     CDS             2294..2665
                     /locus_tag="ACF3UO_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658171.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="ACF3UO_002214"
     CDS             complement(2921..3163)
                     /locus_tag="ACF3UO_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3658172.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="ACF3UO_002215"
     CDS             complement(3195..4097)
                     /locus_tag="ACF3UO_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3658173.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="ACF3UO_002216"
     CDS             complement(4110..4298)
                     /locus_tag="ACF3UO_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3658174.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="ACF3UO_002217"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="ACF3UO_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3658175.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="ACF3UO_002218"
     CDS             complement(4913..5806)
                     /locus_tag="ACF3UO_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3658176.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6807)
                     /locus_tag="ACF3UO_002219"
     CDS             complement(5884..6807)
                     /locus_tag="ACF3UO_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3658177.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="ACF3UO_002220"
     CDS             complement(6856..7206)
                     /locus_tag="ACF3UO_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3658178.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="ACF3UO_002221"
     CDS             complement(7239..8141)
                     /locus_tag="ACF3UO_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFD3658179.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="ACF3UO_002222"
     CDS             complement(8134..8991)
                     /locus_tag="ACF3UO_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFD3658180.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="ACF3UO_002223"
     CDS             9325..10134
                     /locus_tag="ACF3UO_002223"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3658181.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="ACF3UO_002224"
     CDS             10174..10671
                     /locus_tag="ACF3UO_002224"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFD3658182.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="ACF3UO_002225"
     tRNA            complement(11056..11129)
                     /locus_tag="ACF3UO_002225"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
     gene            11316..11639
                     /locus_tag="ACF3UO_002226"
     CDS             11316..11639
                     /locus_tag="ACF3UO_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658183.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11803..12057
                     /locus_tag="ACF3UO_002227"
     CDS             11803..12057
                     /locus_tag="ACF3UO_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658184.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12127..12372
                     /locus_tag="ACF3UO_002228"
     CDS             12127..12372
                     /locus_tag="ACF3UO_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3658185.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12448..12813
                     /locus_tag="ACF3UO_002229"
     CDS             12448..12813
                     /locus_tag="ACF3UO_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFD3658186.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12874..13437)
                     /locus_tag="ACF3UO_002230"
     CDS             complement(12874..13437)
                     /locus_tag="ACF3UO_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658187.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4089 a         2577 c         2304 g         4977 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgctta
    11281 ttttagaaaa aatgttattc ttttatttat tctcaatgtt aggagtgatt attttgccat
    11341 ttattgcgat tttattcgat ttagttgcgg cagcagctta ttttctccaa ttaaattatc
    11401 aaacctcagg aattctgttt attggaatga tttttcaagg tgtgattacc cttttgcttc
    11461 ttgtcatgat gctcagctat aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg
    11521 ttaaatatgt ttccattcgc tatgggatca tcattctttc ctttttagtg aatgcgatcg
    11581 tcctcttttt atatgtattg aattacttag atatcaatcc attgattttt tctcgataga
    11641 taagacacat tcagcggaac agttcctgct tatcagcaga aaactgttct gctttttcat
    11701 ttttcattga tctattcttc ttttattttc ctagcatttc atttgtgatg tatgcaataa
    11761 catgttatct tttattatat gaatcgttga ggagtccgtt acatgattac gttggtgaga
    11821 gttttgtttt gggtgcctgc ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg
    11881 aacaaagaac ggttttattt agctattttg actcttccgg ctatctactt tatgtggaaa
    11941 gtttttaatt acaactactt tgaacccgat agtgttttta tagaagaatt atcaggactg
    12001 gttttgtctt tattgatcgt cattctttat ttgatacgtt taaataaaaa acattgagta
    12061 ctattgattg catgtgtagc tttctatagt cattataact attctactat aatgaaaggt
    12121 gattaaatga gtatcgaaga agctatttta ctggatactt tacgttgtcg tctgaatttc
    12181 ttaagaactg gccgatcttt atctcaagta gctgtttcta gcgcgttaag tattccttta
    12241 ttcaaatatc gtaagtacga agaaggagaa gaaattccaa gcatcattga attaatctat
    12301 atcgctgact tttacgatat ttccgttgat tacctaattg gtcgctcaga aacagcaagc
    12361 aaactgaagt gattttttcc agccttggtg ctggtttttt catttaacgt ctaaggttaa
    12421 caatctatat ataaaggaga catttctatg cgattatggc atgaaaaatt gatttcaaag
    12481 cttcctcgtc aacagctttt aggacaacat cgggaatgct gtgcattaag aggaaatggc
    12541 tggggaaaga aacatgctac tgtggattat gtttttcact attctcctta tagattattc
    12601 caatatcatc agcttgtcat ggatgaaatg gaaaaacgtg gttacagccc agcaccagag
    12661 tggaaaaatc ctatgtatcg tggcaaatca tgcgaagcat tttttgattt acctactgta
    12721 gagcgcaacg tgccgattta tccggaacac gatgaagttt atctagcaga atgtttagca
    12781 aatttggagc aaaaaggaat ttatcttacc taatataact agaaaagcct tctatctcct
    12841 cttacttcat taaaaagctt taaccatctt agatcaagct aaaatgtcgt aagttttagg
    12901 gttatcttca tcctcacgtg caaaactaaa agcgtactct agttttggtt catcgccaac
    12961 ttccctagac ataaatgaac atctcctgac gtggtttaaa agtaccgcat cttcgacgtc
    13021 tgtatacgat gcacagcaca gattgcttct tttgatcttt cttttgattt ttctgttgct
    13081 tcttctacac cttcttcgat tactacatcg atgcttacaa ttgcttctgc ctaatattcc
    13141 catgcatcgt cgatttaagc ctctgtagtc actgtgatcg tttccacatt ttaactcctc
    13201 tgtcgtggct tcagttgatt ttgtgatcag ttcagttgct aagccagagt cagaacaacc
    13261 tgccattgct agcgttaata ttgatagtaa aaatagtttt tttatcataa ggttcccccc
    13321 ctgaaaatag actaaaataa taacgctttc tttttttgtt ttcagacgaa aattaataat
    13381 ttctaaatat tctttaaaaa agcttataac tattatgcct tttttaatat ataacacagt
    13441 tatttttaaa aataagaatg ctaaatcact ctacaataac ggcgaaagca caaaaaataa
    13501 aaaaattatt acgttattaa aaaaacagat gaaagatcag gttttattag atctcattct
    13561 ttcatcactt gaagggattt aatgaactac tttttcctct ttgtcgtttt tatatattcg
    13621 tattccttca aacagtagga tagcctcttt caatgcttga tatttgaact gtccgttact
    13681 taaaaattta gatgtgccgc cctcttccta gaacatattc ttttttactt tttcattaat
    13741 tgacagacca atcgaacgaa actgtaaatt tcgataggat aatgattggt caaactcatt
    13801 cattttcaag acatctcgat tcatattcaa gataggaatc tttttatcaa catcacttta
    13861 ttcgtatttt cctctaccat aaaagcttca cgctccacaa aattgtttta tacactacta
    13921 ttcagcccat tcaacgacca atgaatt
//
LOCUS       DAXLPQ010000058        13835 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.058, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000058 DAXLPQ010000000
VERSION     DAXLPQ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.058"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(44..448)
                     /locus_tag="ACF3UO_002231"
     CDS             complement(44..448)
                     /locus_tag="ACF3UO_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3658188.1"
                     /translation="MTNEIILMSHGLMAEEILNSAKMILGNQINYPVVSMTQNDGIEG
                     TINKLNKILEETSDIRNIIILVDLMGGTPANVAMMKASMDKRIQVVTGMNLGMVLESY
                     FKINEEKLAEHLIEIGKSSIKIPEIQMDGGEE"
     gene            complement(463..945)
                     /locus_tag="ACF3UO_002232"
     CDS             complement(463..945)
                     /locus_tag="ACF3UO_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3658189.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDTVANND
                     IQKQVLRMAVPAGISSSIITEEKAITNIKNGKYEGQNVLLIVKSPVDLLSFIENDLQI
                     DRINVGNMSNRKGTTVLRPNISVTNEERNAFEKLLNLGVEITTIMTPDDKKTYLKDIL
                     "
     gene            complement(965..1777)
                     /locus_tag="ACF3UO_002233"
     CDS             complement(965..1777)
                     /locus_tag="ACF3UO_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3658190.1"
                     /translation="MNSLETTKLGVNSKIKKSVLWRWFFTSSVSSNYEKMQALAYCYA
                     VLPFLKVTYKNKPEALQKAVLNHLQFFNTNPWVAPYILGINIAMEENSDENTEEAVTS
                     IKTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPVGIILWIAVSVALKMISIPL
                     FRIGYTSGTKLITTIEKSLKLLTESTSILGLMVVGALIPSVVKTNVVLDFKQGDFSMR
                     GQEILDQIMPGLLPALLVGLVYWSLKKNVKPIYLILGVMVLSIVLATLGILK"
     gene            complement(1770..2555)
                     /locus_tag="ACF3UO_002234"
     CDS             complement(1770..2555)
                     /locus_tag="ACF3UO_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3658191.1"
                     /translation="MEISVIQLGLIVLYGFFINFEKNSTMFGTYQPVTAGFVTGLILG
                     DIKTGLFIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTGQESSVGISIGIPV
                     ALLMVQLDIIRNTIGIWMVHKAEAGVKRGDYSMISKMQMFGVFLTAATTGIPVALAVI
                     FGPSLINTILAHTPEWLTNGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVMSVY
                     LKMPLLGVALIGAAIALIIYKKNSQNVINNTVVNTIGGMDEDE"
     gene            complement(2555..4630)
                     /locus_tag="ACF3UO_002235"
     CDS             complement(2555..4630)
                     /locus_tag="ACF3UO_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HFD3658192.1"
                     /translation="MKEVINIESNYFSRKFDDELLIIEAWGENAIRIRSFVDMNYEDR
                     QNSLIDKPNSLNKVIINQYENKTELINGKIRAVLDHRDRLTFYNEKNDVLLKEYIRLR
                     AVKHDDGGEDAGSVEVTKDFNSTLKLKSREYRSNMDGKFQVTTRFESDPKEKIFGMGQ
                     YQHSYLDLKNTVLELAQRNSQVSIPFYISSLGYGFLWNNPGIGEVSFAKNITRWKMYS
                     SDYIDYVIISGNEPKEILRNYSNLTGKVPKMPDSLLGLWQSKLRYRSPEEVMDVVEKY
                     HKRGIKLSTIAIDYFHWPKQGEYCFDEEYWPNPEKFLKTLKTDYGVEPIISIWPTVQT
                     DAENYEKYLENGYLVKVNRGVRLTMQIQGNTIFIDMTNSEARKYVWSLIKKNYVDKGI
                     NYFWLDVAEPGYSVYDFDNYRYKKGTDLYSGNLYPIDYLSMIYEELSNEQPVITLVRG
                     GWAGAQRFGALLWSGDIDSSFEAFRNQVNTGLNVGLAGIPWWTTDIGGFHGGNPEDPE
                     FRELLIRWFQYATFSPILRMHGDRLPHSKPLSDHGGGSMVTGAPNEIWSYGIEVEQIL
                     TKYIKIREALKPYISTLMDKAHRFGDPIMRTLFYEYPSDNNTWAVEDTYLFGDTFLIA
                     PIVNYKETVREVYLPINENWTNIWTGEEYDGGQTLDVEADISMIPVFIKTNQKDKFSK
                     LLSIIKEEI"
     gene            4938..6104
                     /locus_tag="ACF3UO_002236"
     CDS             4938..6104
                     /locus_tag="ACF3UO_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3658193.1"
                     /translation="MISSKYTIREQNEAKILNQIIRHKEISRAELSKITSLNKASVSS
                     IINKLIDDSLVIENRIGEATNRGRKPIMLTFNGVSSGLAIAIDLGYNYIDGMVASLDG
                     KEIARIQLTDTYVSKDNIQMLIRKIIKKLTDNLPYTRHGIIGMTIAVQGQVLNNKVLS
                     TTYNGLEEIDLVKLLNQEYSFPVFLQNEANLSALGEYTFSSDIENLVSISLHSGIGVG
                     VVKNGKLDIGNKGYAGQLGHTILFPNGRKCECGNYGCLEKYCSTQVIYQEISKEKKLD
                     KINSDIVEYLYSNKDQKVVEMIELYAYYLSIGINNIVMLYAPELVIFNSPLTKKIPNI
                     INIIKNFLNNQYTKEIHIINSPIEWNPVLSGAISFSIQKFLNIEKLKLSSYAKN"
     gene            complement(6696..7175)
                     /locus_tag="ACF3UO_002237"
     CDS             complement(6696..7175)
                     /locus_tag="ACF3UO_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFD3658194.1"
                     /translation="MIKFLRKKKQVELFSPCSGKVIPISEVNDPVFSQKLLGEGFAVI
                     PEEQTIYAPLAGQVTTIFPTKHAISIKSNSGIDYLIHIGIDTVELEGKPFSILVDEKE
                     YITPENPLVKVDFKQLELAKKDSSVIICFTESSQIDNLDLYTGRVLHGVLCGYLNLS"
     gene            complement(7187..8689)
                     /locus_tag="ACF3UO_002238"
     CDS             complement(7187..8689)
                     /locus_tag="ACF3UO_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3658195.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPIL
                     AQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVSYLVYTATI
                     SGFLELFSVKDATLDTGVVGSIAIGGIVAFLHNRYRKIELPQFLGFFGGSRFIPIISS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEHIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTESVAGITVSGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGLAWAIIYFIVFTFFL
                     KKFKVAIPGMIEEKEVVSEINLNKNTSLHEESLMIIKALGCEENIESVEACATRLRVA
                     VKNGQNVDKQAIKQLGATAVFEVKGGIQAVFGGKADLLSQEINQILKRDN"
     gene            complement(8682..9389)
                     /locus_tag="ACF3UO_002239"
     CDS             complement(8682..9389)
                     /locus_tag="ACF3UO_002239"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFD3658196.1"
                     /translation="MKKQIFLDAISGGLIVSCQALPGEPFYKEEGGLMSYFALAAERA
                     GAVGIRANSVRDILEIKEKVSLPMIGIIKRDYPPEEPFITATMREVDELVATGVEVIA
                     LDCTLRKRHDNLSINTFITQIKEKYPEQLLMADISTFEEGKNAYEAGVDFVGTTLCGY
                     TNESRKQEGPAIDLMKQLVQAEICVIAEGKIHTPEQAKKIRELGVSGIVVGGAITRPQ
                     EIAERFVNALKEEEKNV"
     gene            9552..10370
                     /locus_tag="ACF3UO_002240"
     CDS             9552..10370
                     /locus_tag="ACF3UO_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3658197.1"
                     /translation="MNYIYLIKEHYPLLTKSEKKVADLILDSGKAIIYSTMSDIKEKT
                     TVGDATIIRFCQKLGFSGFSDLKIEIAKEDFSKKKEYPSSEKYYDIIATHLTEALYST
                     AHLLDEKKLDKAIQLISQAKNLYIFGVGSSGNTSLDLESMFLRVGVQAKAVLDPHFQA
                     QVASLMEEDDVIIAFSLSGKTKDTFDSVEIAKKNGAKILAITNYLHSPIGQTADVVLQ
                     TAIEEFLNGGSLAGKISQLYLCDLLVQGYEQKNNINAVELRERVLRSILDKSLD"
     gene            complement(10731..11357)
                     /locus_tag="ACF3UO_002241"
     CDS             complement(10731..11357)
                     /locus_tag="ACF3UO_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3658198.1"
                     /translation="MTISNKNSMREEIIIIAIKHFSKFGYEKTRLLDIANEAKTSTTT
                     VYSFFKTKHDLYEAAVEYDLNIINLELEKIVKESSTLDEYIINIVERVRLNSEKKQLF
                     LNFFMLISTNSGQIKKIDIIEEFERKKFSFYFKFIESPKVKDRYTLLFIDNLITIYIY
                     SYFNVFYRKKLLLYLSLYQQDKQSIEFEEDLLKHLKILIRTRLFIDKN"
     gene            complement(11364..12008)
                     /locus_tag="ACF3UO_002242"
     CDS             complement(11364..12008)
                     /locus_tag="ACF3UO_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3658199.1"
                     /translation="MYKTANELFNRLKSEKKELILNYILEEFGRVGYESASVRKIADK
                     ADLSAGSLYQYFNNKEGMLRVAIEHVFVILDEYINNINNAPLKLENRLEVMFETILEL
                     GRKHPELIVFYNKIPGDEQMTSEWVKQFYNNTSFFKVYWHTVNELQDEKEISDKIDPV
                     VYTFIIDTMMLSGELLQNTQYQEIKAKIFLEDSIKSSLILKENVIETLTVLARG"
     gene            complement(12428..13552)
                     /locus_tag="ACF3UO_002243"
                     /pseudo
     CDS             complement(12428..13552)
                     /locus_tag="ACF3UO_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4659 a         2513 c         1871 g         4792 t
ORIGIN      
        1 tttttcaatt gagattaaca gaactattct tccttcatta taattactct tctccaccat
       61 ccatctgtat ctcaggtatt ttaatactac ttttacctat ttctattaaa tgctcagcaa
      121 gtttttcttc attaatttta aagtatgatt ctaataccat ccctagattc attccagtta
      181 ctacttgaat tcttttatcc atacttgctt tcatcatagc tacatttgca ggtgttcctc
      241 ccattaggtc tactaatata ataatatttc gtatgtcact tgtttcttcc agtattttat
      301 tcaatttatt tattgttcct tcaataccgt cattttgtgt catagaaact accggataat
      361 taatctggtt tccaagtatc attttagctg aatttaatat ttcctcagcc attaaaccat
      421 gactcattaa aattatttca ttagtcatcg cacttattcc ccttataaaa tatcttttaa
      481 gtaagttttt ttatcgtctg gtgtcataat tgtagtaatt tcaacaccaa gatttaatag
      541 cttctcgaag gcatttcttt cttcattagt aacgctaata ttaggacgta aaaccgttgt
      601 tccttttcga ttagacatgt tgccaacgtt aatcctatct atctgtaaat cattttcgat
      661 aaacgataat aagtctactg gggatttgac tattaaaagc acattttgcc cttcatattt
      721 tccattttta atattggtaa tcgctttctc ctcagttata attgaagaac tgattcctgc
      781 agggactgcc atccttagca cctgtttttg tatatcatta tttgcaacag tatcatttac
      841 aaccatcaaa cgagtcacac ctaatttatt actccacatt gtagctactt gaccatgaat
      901 taatcgatcg tcaattctaa tattttttat acccttcatt tccacaaaaa tttcctccta
      961 tcatttattt taaaatgcct agagtagcta aaacaataga cagaaccatc acaccaagaa
     1021 ttaaataaat aggttttaca ttttttttca aagaccagta aactaaacca actaaaagtg
     1081 caggtaataa tcctggcatt atttgatcta gtatttcttg ccctctcata gaaaaatcac
     1141 cttgtttaaa atctaagacg acatttgttt taacaacaga tggtattaat gctccaacaa
     1201 ccattaatcc taaaattgaa gtcgattcag ttaaaagttt taaacttttt tcaatagtag
     1261 taattaattt cgtacctgaa gtatagccta tgcgaaataa tggtatactt atcatcttta
     1321 aagctacact tacagcaatc cataaaataa ttcctactgg actaccatca attgccatat
     1381 ttgctgcaat agccccaaat atagtccatg gaataactac aaatagacta tcacctaatc
     1441 cagctactgg ccccataagt cctgtcttaa tcgatgtcac tgcttcttca gtattttcat
     1501 ctgaattttc ttccatagct atattaatac ctaaaatata cggtgcaacc caaggatttg
     1561 tattgaaaaa ttgtaaatga tttagtactg ctttttgtaa cgcttctggt ttgtttttat
     1621 aagtaacttt taagaatggt aatacagcgt aacaatatgc tagagcttgc atcttttcat
     1681 aatttgaaga aactgagctt gtaaaaaacc atctccataa tacactcttt ttaattttgg
     1741 aattaacacc aagttttgtc gtctccaagc tattcatcct catccatacc tcctattgta
     1801 ttaacaacgg tattattaat tacattctga ctattttttt tataaataat taaagctata
     1861 gcagcgccta ttaatgctac tcctaataat ggcattttta agtaaacaga cattacaaaa
     1921 ccgataacaa gataactgaa atattctttt gcaggtaagt atcgaagcaa taaaccaata
     1981 ccaacagctg gtaataatcc cccagcaact gttaacccat ttgttaacca ttcaggagta
     2041 tgagcaagaa tagtattaat taaagatggt ccaaaaatta ctgccaacgc aaccggtatg
     2101 cccgttgttg ccgccgttaa gaatactcca aacatttgca tcttggagat catactataa
     2161 tctcctcgct ttacacctgc ttctgcttta tgaaccatcc aaataccaat tgtatttcta
     2221 ataatatcta attgaaccat taatagtgct actggtatac caatagaaat ccctaccgaa
     2281 gattcctgac cagttgttat ggtgataaaa gttgcgacaa tacttgcagt ttgatagtct
     2341 ggtatagaag ctcctccaaa attactaatt cctaaagaca ataattgtaa ggttccccca
     2401 ataaaaagcc cagtttttat atctccaagt attaaaccag ttacaaatcc cgctgttaca
     2461 ggttggtagg ttccgaacat tgttgaattc ttctcaaaat taataaaaaa accatataac
     2521 acaattaaac caagttgaat aacacttatc tccattagat ctcctcctta attatactta
     2581 atagttttga aaatttatct ttttgatttg tctttataaa aacaggtatc atactaatat
     2641 ctgcttcaac atccaacgtt tgtccgccat catattcttc acctgtccat atattggtcc
     2701 agttttcatt tattggtaag taaacttctc ttactgtttc cttataattt acaatcggtg
     2761 caattaggaa cgtatctcca aataagtaag tatcttctac agcccaagta ttattatctg
     2821 aaggatattc ataaaatagc gtcctcatga tcggatctcc gaatctatga gctttatcca
     2881 tcaaagtact gatatacggt ttcaacgctt cacgtatttt tatatactta gttaatatct
     2941 gctcaacttc tataccgtat gaccatattt catttggtgc accagtaacc atcgaacctc
     3001 caccatgatc cgataagggt ttactatggg gtaatcggtc accgtgcatt cttaaaattg
     3061 gtgaaaaagt agcatattga aaccaacgaa ttagcaattc tctaaactcc ggatcttctg
     3121 gatttccgcc atgaaaccca cctatgtcag ttgtccacca gggaatccct gctaaaccta
     3181 catttagtcc agtattaact tgatttctaa atgcttcaaa actagaatca atatctccag
     3241 accacaataa tgcaccgaat ctttgtgctc cagcccatcc tcctctaaca agagtaatta
     3301 caggctgttc attacttaat tcttcataaa tcattgaaag ataatcgatt ggatataaat
     3361 taccactata taaatcagtc ccctttttat aacgataatt atcaaagtca taaacggaat
     3421 atcctggctc agctacatct aaccagaaat aattaatccc tttatcaaca taattctttt
     3481 taattagact ccaaacatat ttccgagctt cactatttgt catatcaata aaaatagtgt
     3541 ttccttgaat ttgcatggtt aatcgaactc cacgattaac ttttactaga taaccatttt
     3601 ctaaatattt ttcataattt tctgcatcag tttgtactgt aggccaaatt gagattattg
     3661 gttccactcc gtaatcagtt ttcaaagtct ttaaaaattt ttctggatta ggccagtatt
     3721 cctcatcaaa acaatattct ccttgctttg gccagtgaaa ataatcaata gcgatagttg
     3781 aaagctttat tccacgttta tgatactttt ctactacatc catcacttcc tctggtgatc
     3841 tatatcgtaa tttgctctgc cataatccta ataaactatc tggcatttta gggacttttc
     3901 cagttagatt actatagttt ctaagtattt cctttggttc atttcctgaa attattacat
     3961 aatcgatata atcagaagaa tacattttcc atcgagttat atttttagca aaagaaactt
     4021 ctccaatacc aggattattc cataaaaaac cgtatccaag actagatata tagaatggaa
     4081 ttgacacctg tgagtttctt tgcgctaatt ctaaaacagt gttcttcaaa tcaagataag
     4141 aatgttgata ttgacccatt ccgaatattt tttcttttgg atctgattca aatctagtag
     4201 ttacttgaaa tttaccatcc atattggaac gatattctct tgactttaat ttcaatgtag
     4261 aattaaaatc ctttgtaact tcaactgaac cagcatcttc accaccatca tcatgtttaa
     4321 cagctcttaa tctaatatat tcttttagta agacatcgtt tttttcatta taaaaagtta
     4381 aacgatcacg atgatctagt accgctctta ttttcccgtt aattaattct gttttatttt
     4441 catattgatt tattatcact ttatttaggg aattaggctt atcaattaag gagttttgtc
     4501 gatcttcata gttcatgtct acaaatgaac gtattctaat agcattttcc ccccatgctt
     4561 caataatcag taattcatca tcaaattttc ttgaaaaata atttgattca atgtttatca
     4621 cttctttcat cccactttcc ttttcttctt aattagttaa ctcttattac aacactagca
     4681 attgtaatcg catacatata catatcaatt taatttaagt attttgacta gaattctgct
     4741 ttttaatttg ttttctcgat aaactaatta tcaaaaaaaa aactaataac aaaaaacact
     4801 taattacttg aactaaaatt gtttgtacgt taaactaatt aataaataaa atataaaata
     4861 agctatttaa aatgtcaact gtaaacgcta tatttttttt gcataggcta ttttattttt
     4921 aaattgagga gaaattaatg atttcaagta aatatacaat tagagaacaa aacgaggcaa
     4981 aaatacttaa tcaaataatt agacataaag aaatatctag agctgaattg agtaaaataa
     5041 cctctttaaa caaagcatct gtatcttcta ttatcaataa attgatcgat gactcgcttg
     5101 taattgaaaa tagaattgga gaagcaacaa atcgtggccg aaaacccatt atgttaactt
     5161 ttaatggagt atcttcgggc ttagcaattg caattgatct aggatataat tacattgatg
     5221 gaatggtagc ttcattagat ggaaaagaaa ttgcaagaat acagcttact gatacttatg
     5281 ttagtaaaga caacatacaa atgttaattc gtaaaattat aaaaaaactc accgataatc
     5341 ttccttatac gcgacatgga ataatcggta tgacaattgc tgttcaagga caagttctaa
     5401 ataataaagt acttagtaca acttataacg gtcttgagga aattgatcta gtaaaattat
     5461 taaatcaaga gtatagcttt cctgtttttt tacaaaatga ggcaaactta tctgcattag
     5521 gtgaatatac tttttcttct gatatcgaga atttagtatc aattagtctt catagtggaa
     5581 taggcgttgg agtagtaaaa aatggtaaac ttgacattgg taataaagga tatgctggtc
     5641 agttgggaca tacaattcta tttccaaatg gcagaaaatg tgaatgtggt aattatggtt
     5701 gtttagaaaa atattgctct actcaagtaa tttaccaaga gatttccaaa gaaaaaaaac
     5761 tagataaaat taattcggat atagtggaat atctttatag caacaaggat caaaaggttg
     5821 tagagatgat tgaactatat gcatactatt tatcgatagg aattaacaat atagttatgc
     5881 tctatgctcc tgagttagtg atttttaaca gtcctttaac aaaaaaaatt ccgaacataa
     5941 ttaatataat caaaaatttt ttgaataatc aatatacaaa agaaattcat atcattaaca
     6001 gtcctataga gtggaatcct gttcttagtg gagcaatttc gttttcaatt caaaaatttt
     6061 taaatattga aaagttgaaa ctcagctctt atgcaaaaaa ttaatttaat ttagtggaaa
     6121 ctagtatgtg aaatggagaa attttaacat actagacggc tcaccagtac tctctcctta
     6181 aaaagagctt tttatatagt tatgaatttc tcaccgctct acctcttttt caagagataa
     6241 aaaaattaat acaatgctta ttacttaaac tatttctaac tcaataatct atcaaatatt
     6301 ctcaattttt ttcaattgtc tttttgttta atcaaagcat gcttgcttat tatccatttg
     6361 gcctatactt tagggtaaaa ttttacaatt tcatctaaat tatatactaa acttttatcg
     6421 ctattaaaag taaaaacagc ttcgcccacg tatagaaacg tatatctttt tgtttctaca
     6481 cgtgggcgag ctgactaaaa tcatataatc aaaaacttaa taaaacgagg ttcactccaa
     6541 tcatatttca tttttcaaaa ctatcacatt aatctcttgt caatcaaaat tattatacat
     6601 tgagaaagtt acaacttata tactacttct ttaaactcta aaacttcacc aatgagtttc
     6661 taataattag atcttattaa tctaactatt aatcattatg ataaatttaa atacccacaa
     6721 agaacaccat gtaaaactct tcctgtatat aaatcgagat tatcaatttg actagattca
     6781 gtaaaacaaa tgattactga tgagtctttt ttagccaatt caagctgttt aaaatcaacc
     6841 ttaactagtg gattttcagg tgttatatat tctttttcat caacaagaat tgaaaaaggt
     6901 tttccttcta attctactgt atctatccca atatgaatca aataatcaat tcctgaatta
     6961 ctctttatac taatagcatg ttttgttgga aagatagttg tgacctgacc agctaaagga
     7021 gcataaattg tctgctcttc tggaataaca gcaaaacctt cccctaataa tttttgtgaa
     7081 aaaactggat catttacttc tgatatagga ataacttttc ccgaacatgg agaaaatagt
     7141 tccacttgtt ttttctttct taaaaactta atcatataaa ttcctcctaa ttatctcttt
     7201 tcaaaatttg attgatttct tgactaagta aatcagcttt tcctccaaaa actgcttgaa
     7261 tcccaccttt tacctcaaaa actgcagtag cacctaattg ttttatagct tgtttgtcaa
     7321 cattttgtcc attcttcaca gcaacacgca agcgagttgc acaggcttca acagattcaa
     7381 tattctcttc acagccaagt gcttttataa tcattaaaga ttcttcatgc aaagaagtat
     7441 ttttattcaa gttaatttca gagactacct ctttttcttc tatcatacca gggatcgcta
     7501 ctttgaattt ttttaaaaag aaagtaaaaa cgataaagta aataatagcc caagcaagtc
     7561 caaaaggaat caatttaagc cagttagttt tgtcatttcc ttgaagtaca ccaaataata
     7621 gaaaatcaat tagtccacct gaaaaagaat ttcctactcg aatattcagg atatccgcaa
     7681 aataaaaaga taggccgtct aaaaatgcat ggatgacata aagccatgga gccacaaaca
     7741 gaaacatata ttctacaggc tcagtgattc ctgttaaaaa cgaagttaat gcaccgctga
     7801 aataaagacc gccatttttc ttacggtttt ttttaggaat tgcacgatac atcgcataac
     7861 aagcagcagg aaggccaaac atcatcgtgg caaatcttcc agcaaaaaaa cgagtcccat
     7921 aagtaaataa gcctgtgtga ttcggatcag ctaattgagc aaagaaaata ttttgtgccc
     7981 cagaaactgt aattcccgct acactctcag ttccccctaa cgaagtgtac cagaaaagtg
     8041 gataaattgt atgatgaaga ccaacagcac cagttaaacg aagtaaaaat ccataaagaa
     8101 atgttcctag actccccatt tgagcaatat gctctccagc aacaactaat ccattctgaa
     8161 tcggtggcca aattagataa aagaaggaac caataataat tgcagccaaa ctagaaataa
     8221 ttggaataaa acgtgaacca ccaaagaatc ctaaaaactg cggtaattct atttttctat
     8281 agcgattgtg taaaaatgcg acaattccgc caatggcaat tgaacctaca actccagtat
     8341 caagagttgc atctttgaca gaaaataatt caagaaaacc actaattgtt gctgtataaa
     8401 ctaagtaaga aacaccacca gctaaaccag cagttccttt gtcaccattt gcaagcccca
     8461 ctgcgatacc aatcgcaaat atcaatgcta aattagcaaa aacggcgtta ccagcataac
     8521 tcatgatact caaaatcgta tgaagccacg gttgagctaa tatgggataa gcatttatgg
     8581 cgctttcatt tgtcagtgca ccgccaagac ctaaaagtaa accagcaaca ggtaaaatag
     8641 cgatcggcaa cataaatgcc cgacctagtt gtgaaaattt tttaaacatt tttctcttcc
     8701 tccttcaatg cattgacgaa acgttctgca atttcttgtg gacgagtgat cgcgccacca
     8761 actacgattc cagaaacacc taattcccta attttttttg cctgctctgg ggtatggatt
     8821 tttccttctg caataacaca aatttctgct tgaacgagct gtttcatcaa gtcaatcgct
     8881 ggcccttctt gctttctact ttcattagta tatccgcata acgtggttcc gacaaaatca
     8941 acgccagctt cataggcatt tttaccttct tcaaaggtag agatgtctgc cattaataat
     9001 tgttcaggat acttttcttt gatctgagta atgaaagtgt tgatagacaa attatcatgg
     9061 cgtttgcgca gcgtacaatc tagcgcaata acttctacac cagtagcaac taattcatcg
     9121 acctcacgca tcgttgcggt aataaatggt tcttcaggag gataatctcg cttaattatc
     9181 ccaatcatag gtagagaaac tttttcttta atctctaaaa tatctcgaac agaatttgct
     9241 cggataccaa ctgcaccagc tctttcagca gctagagcaa aataggacat aagacctcct
     9301 tcttctttat aaaatggttc accaggtaat gcctgacaag aaacaatcag tccacctgaa
     9361 attgcatcta aaaatatttg tttcttcatt ctcctaaaca ctccacttta aattaatttt
     9421 cggataataa ctccaaataa aatatagcac gcgctttcat tgatgtaaag tataaaaatg
     9481 gataaatttg gagatttttt tatctttttg gagtataatg gagtaaaatt ttttactgta
     9541 aaggagttca tatgaattac atctatttaa ttaaagagca ttatccttta ttgactaaat
     9601 ctgaaaaaaa agtagctgat ttaatcttag attctgggaa agcaattatt tatagtacaa
     9661 tgagcgatat caaagaaaaa accacagttg gggatgcaac gattattcgt ttttgccaaa
     9721 aattaggatt ttctggtttc tctgatttga agatcgaaat tgcaaaagaa gatttcagta
     9781 aaaaaaaaga atatccgtca agcgagaaat attacgatat aattgctact catctaactg
     9841 aggcgctcta ttctacagca catttactag atgaaaaaaa actagataag gcaatccaac
     9901 tcatcagtca agcaaaaaat ctttatatat ttggggtggg ttctagtgga aatacaagcc
     9961 ttgatttaga aagtatgttc ttacgagtag gagttcaagc aaaagctgtt ctggatcctc
    10021 attttcaagc tcaagtagct tctttgatgg aagaagacga tgtgattatt gctttttcat
    10081 tatccggaaa aacaaaagat acctttgatt ctgtagaaat tgcaaaaaaa aatggtgcaa
    10141 agatcttagc aattaccaat taccttcatt ctccaatagg acagacagca gatgttgttt
    10201 tacaaacagc aatcgaagaa tttttaaatg gtggttcttt ggcagggaaa atctctcaat
    10261 tgtacctttg tgatttactt gtacaaggtt atgaacagaa aaacaatatt aatgcagtgg
    10321 aattacgtga aagagtatta cgctctatct tagataaaag cttagattaa atagagtatt
    10381 aattgaagca atttatattt aggtgaaata tcaattaatt agtgggactc acaatttgca
    10441 caaataactt tcatcttacc tttagatgaa gtgttagaaa gaaaagtatc aaccatcaat
    10501 actttgaaaa aattcttttt ataggaatat gatgaacagc tttcaatata caataatcat
    10561 tatcaaagat aactgacaac ttttagcaat aaaatacaaa acactttttt agtcagtatc
    10621 taaatataac aaatctattt cataaagcaa aaaagcggct agacaaaaga gatgtctaac
    10681 cacttacatt tatcatctat ataattcaat gaacagagaa aaaaaggaca tcagttttta
    10741 tcaataaaaa gtcttgttct tatcaatatt ttcagatgtt ttagcagatc ctcttcaaat
    10801 tctatagatt gtttatcttg ttgatataaa gatagataaa gcaataattt ttttcgataa
    10861 aatacattaa aatatgaata gatataaata gtaattaaat tatctataaa caataatgta
    10921 tagcgatctt ttaccttagg ggattctata aatttaaaat agaaagaaaa tttttttctt
    10981 tcaaattctt ctataatatc tatttttttt atttggccag aattggtcga aataagcata
    11041 aaaaaattca aaaacaattg tttcttttca gaatttaatc gtactctttc aactatattt
    11101 ataatatatt catcgagtgt agaactttcc ttaacaattt tttcaagttc aaggtttatt
    11161 atatttaaat catactccac tgcagcttca tacagatcat gttttgtttt aaaaaaacta
    11221 tatacagtag tagtactagt tttagcttca ttagcaatat ctaaaagtct tgttttctca
    11281 taaccaaatt tagaaaaatg ctttatagca ataattataa tttcttctcg catgctattc
    11341 ttattactta ttgtcataga ctcttacccc cttgcaagta cagttagcgt ctcgataaca
    11401 ttttctttta atattaatga actttttatt gagtcttcta gaaaaatttt ggcttttatt
    11461 tcttgatatt gcgtattttg aagtaattct ccggataaca tcatcgtatc aataatgaac
    11521 gtgtagacaa ctggatcaat tttatcactt atttcttttt catcttgtaa ttcatttacg
    11581 gtatgccaat atactttgaa aaaactagtg ttattgtaaa attgtttaac ccactcgctt
    11641 gtcatttgtt cgtcaccagg aattttatta taaaaaacaa tcaattcagg atgttttctt
    11701 cctaattcta agattgtttc gaacattact tctaaacgat tttctaattt taaaggagca
    11761 ttgtttatat tattaatata ttcatctaaa ataacaaaaa cgtgttctat tgctactctt
    11821 agcattcctt ctttattgtt aaagtactga tataatgatc ctgcacttaa atctgcctta
    11881 tcagcaatct tacgaactga agcagattca taaccaactc ttccaaattc ttctaagata
    11941 tagtttaaaa tgagttcttt tttttctgat tttaatcgat taaataattc atttgctgtt
    12001 ttatacatag ctatctcctc aaaaaagata ttataactaa gtataccata ttaaccttat
    12061 aaaaacgacc gctcattttt taaagcttct cctaattgaa tcattttcca accatttact
    12121 tttctactac taataatttc gtctgaacta tttacagaag tgtgacccga cttaatttca
    12181 gaagtcttaa tattttcatt attctttaca agactcctga ctttcaaggg gatataaaat
    12241 aactctagat gtatggaatg gcaacacttt tctagacaaa aattataagg tctgtttatg
    12301 acaccatatc cagttgccct tgacaacgag cctcctcaaa tcggttttct tagcggcgtg
    12361 ctcactttga ataaaataag ccgctcgaac agaaggtaac cgattcttgc tcattatcaa
    12421 gggttcgcta cgccaacctc cgcatagcgt acctcaattg gtgttttata accaagagaa
    12481 ctatggatcc gatgatgatt ccaccaattg acataatcaa aacattctaa ttctaagtgt
    12541 gccatcgttt caaattgata ttgactcaca aattccgtct taaaagcttt gtaagtcgct
    12601 tctgaaacgg cattatcata tggacatcca ggcttactca aggagcgttg aatgccaaat
    12661 gtttctaaga taagatcaat caattcatta tcaaattctt ttccacgatc cgtatggaag
    12721 agttcgattt cttgaagtga gtaaggaatg ctttgaatgg ccctttttac aagctgcgca
    12781 tcttttttat ttccgcaaga atggccaata atttcacgat tgaataaatc aatcatcaaa
    12841 caaatataag cccaatttgt cccgacccga acataagtta aatccgtgac aaccgctgac
    12901 aatgcttttg tttgagtaaa ctttcgatct aagtgattcg caattttctt ttgattgctt
    12961 tggcacgaat gtacgcgata tttgggcttc gtgtaactgg atttcaatcc tcgtcttttc
    13021 atgatgcgac gaatttttcg acgactcaaa atgagatttt tcttatcaag gcgtttcttg
    13081 attctgcgtg aaccatatgc tcgtctattt tgttgaaaaa cttcttccac cgcttcttct
    13141 aattttgctt ctactgcgcc ttgagtcgtt tctttttctc gataataata ggtggctctt
    13201 gcaataccca gtactttaca catggctgat atcgagtatt tgtgcttatt tgcatcaatt
    13261 acttgtcttt tcgtccgaat atcagcgccg cttgctttaa aatatcattt tctatcaaga
    13321 gttgtttatt ttgctttcgc aattgaatta actctttttg ttcaggtgtt aagttatctt
    13381 tttctttaaa tgagccagag gtatttgctt gtttcaccca tttatcaaaa gtagacgggg
    13441 ttaaatcata ctctctgata atatcggttc tctttttccc tgacgcatat aactgaacca
    13501 tttgattttt aaactcttta gtaaacgttc gacgtggttt tctttctgac attaacaatt
    13561 cctccagtgt gttttcttat attttacaca ccttaatttt tctgtctagt taattgtagc
    13621 ctatccaaac aaacgttcat tttataaaaa taagagaaat aatatcatta tgtttcataa
    13681 tatatatgtt aaaataattt taaaaaaaat tcaatatgac tattcatttc tagtttgcga
    13741 atatgactaa agaaagaaaa aagactttac cattagaata aatcagttat aaaaaagaga
    13801 cggtaaatat cgatttcttt aattatctaa ttact
//
LOCUS       DAXLPQ010000059        13715 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.059, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000059 DAXLPQ010000000
VERSION     DAXLPQ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.059"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(71..2068)
                     /gene="tkt"
                     /locus_tag="ACF3UO_002244"
     CDS             complement(71..2068)
                     /gene="tkt"
                     /locus_tag="ACF3UO_002244"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFD3658200.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2170..2421)
                     /locus_tag="ACF3UO_002245"
     CDS             complement(2170..2421)
                     /locus_tag="ACF3UO_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFD3658201.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2568..3191
                     /gene="lexA"
                     /locus_tag="ACF3UO_002246"
     CDS             2568..3191
                     /gene="lexA"
                     /locus_tag="ACF3UO_002246"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFD3658202.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3370..3588
                     /locus_tag="ACF3UO_002247"
     CDS             3370..3588
                     /locus_tag="ACF3UO_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658203.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3876..4388)
                     /locus_tag="ACF3UO_002248"
     CDS             complement(3876..4388)
                     /locus_tag="ACF3UO_002248"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFD3658204.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4402..6699)
                     /gene="recJ"
                     /locus_tag="ACF3UO_002249"
     CDS             complement(4402..6699)
                     /gene="recJ"
                     /locus_tag="ACF3UO_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFD3658205.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6841..7284)
                     /locus_tag="ACF3UO_002250"
     CDS             complement(6841..7284)
                     /locus_tag="ACF3UO_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFD3658206.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7285..8073)
                     /locus_tag="ACF3UO_002251"
     CDS             complement(7285..8073)
                     /locus_tag="ACF3UO_002251"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3658207.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8070..9011)
                     /gene="rnz"
                     /locus_tag="ACF3UO_002252"
     CDS             complement(8070..9011)
                     /gene="rnz"
                     /locus_tag="ACF3UO_002252"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFD3658208.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9188..9775)
                     /locus_tag="ACF3UO_002253"
     CDS             complement(9188..9775)
                     /locus_tag="ACF3UO_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFD3658209.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(9996..11309)
                     /gene="obgE"
                     /locus_tag="ACF3UO_002254"
     CDS             complement(9996..11309)
                     /gene="obgE"
                     /locus_tag="ACF3UO_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFD3658210.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11597..12607
                     /gene="gap"
                     /locus_tag="ACF3UO_002255"
     CDS             11597..12607
                     /gene="gap"
                     /locus_tag="ACF3UO_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFD3658211.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12692..13627)
                     /locus_tag="ACF3UO_002256"
     CDS             complement(12692..13627)
                     /locus_tag="ACF3UO_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3658212.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3769 a         3086 c         2425 g         4435 t
ORIGIN      
        1 ctaacacata aagaacagct gtctccaact tgcagacagc tgttcttatc agtcaaacaa
       61 ttgcttggat ctatgatagt tgattgtacg tattcacgac attttctact gtaaatccaa
      121 attcttctaa aattttagtg ccaggggcag atgcaccgaa atgatcgatt gtaatcgttg
      181 cgccctctgt tcctacgtag cgttcccaac caaatgatgc agcagcttcg atagccacac
      241 gtttcttcac tgatttagga agtacacttt ctttatattc agaagattgt ttttcaaaga
      301 ggtcaaagct tggcatagaa acaacagaaa catctttgcc tttttcagcc aattcttttt
      361 gagctttcac agccaaatca acttcagaac ctgttgcaat caaaatacct tctggtgttt
      421 ctccttgtga tggagaaaga acatacgcgc cttttttcac catttcatct gctacttctt
      481 ttgtagaagg caatactgga aggttttgac gactcaatac aaggatagta ggcgcatctg
      541 ttgtctccat cgctactttc caagcagcac gtgtttcatt tccgtctgcc ggacgaatca
      601 cttgaacacc aggcatgcag cgaacagatg ctagttgttc aatcggttcg tgcgttggtc
      661 cgtcttctcc gacagcaacc gagtcatgtg ttaagacgta aacaacagga gtatgttgga
      721 ttgctgctaa acgaactgct ggtcttagat aatcgacaaa gacaaagaat gttccaccgt
      781 agatacgagt tccgccatga agttggatac cattcatagc cgaagccatt gcaaattcgc
      841 ggacaccgaa ccagatgttg cgtccttcat aatgttcagg agtgaaatct ttatctgcag
      901 ccaccattgt attattggaa cctgacaagt ccgctgaacc accccagaag cttggtatag
      961 ctttcgataa ttcttggatg acttctttac ttgaaacacg gcttgcttga ctgcttccaa
     1021 cttcataagt tggcaattct gcatcccagt tttctggtag tttgccatca aaagcatctt
     1081 caaattgttg tgctaattca ggataagctt ttttataatt ggcaaacatt tcattccatg
     1141 catcttcagc tttttgtcct tcttctatca tcgtttgatg gaagcgggca gctacttctt
     1201 ctggaacagt gaaatctgga tactcccaac cataaacttc tttagccatc ttgatgccat
     1261 cttcaccaat aggagcacca tgaacagcag atgttccttc tttaggagca ccatagccga
     1321 tgactgtttt tacttcgatc aatgttggtt tgtctgtttc agcttttgct tcttcaatcg
     1381 ctttagagat tgcttctagg tcatttccgt ctttcactaa gatatgttgc cagccatatg
     1441 cttcatagcg agcaccaacg ttttctgtga aagcttttga agttggaccg tctagtgaaa
     1501 tatcgtttga atcgtataaa acgatcaatt tccctagttt catatgacct gccatcgaac
     1561 ttgcttcttg agatacccct tccatcaagt ctccgtcacc gcatattgca tacgtatagt
     1621 gatccatcac attaaagttt tctttgttat acgttgctgc aaggtgcgct tctgccattg
     1681 ccataccgac agccattgca atcccttgtc ctaatggccc tgtagtggct tctacaccat
     1741 ctgtgtgatg tacttcagga tgtcctggtg ttttagaatc ccattgacgg aattgtttca
     1801 aatcatcgat tgtcacttga tagccagcta aatgaagcaa gctatacaac attgctgacc
     1861 catgtcctgc cgaaagaacg aaacggtcgc ggtcagccca gttttttgat gtcgttggat
     1921 ttactttcag gtgttttgtc cataacgcat atgccatagg tgctgcgccc atcggcaatc
     1981 caggatgtcc tgagtttgct ttttggactg cttcaatact taatgtacga attgtgttaa
     2041 cgccaagttg gtcaattttg tcaaacaaaa taacccctcc tattaattta ggtttttttt
     2101 acctttattt cttacacttt cattctataa gatgtcacac gaaaaagcaa tctttttcag
     2161 tattttttac taaaagttgt catttcggtt gtgtaagcct tttttctttt ggatttcttt
     2221 taatttttcc ggggtcacgt cattgccctc aggatcgacg actttcattc cttcgatatg
     2281 atgacgcata ccggaacgaa aagcttccaa atactctttg cgtaagttga tttgttcttg
     2341 ttcttcggct tttgagagac cattttcctt ctttttacgt gcaagttcat tgatcctctc
     2401 tattttttca ggtgacagca tgctcagccc tccttttact ctccttcata ttatataaaa
     2461 actgaaaaaa aaacaactag ataaactaaa taaaatacga acattcgttt gatttagcgc
     2521 tttttatatg gtactattta tttatcaagt gaaagaaggt gtaccttgtg gcccgacaaa
     2581 ctgaatcaag acaaatcgaa gtcttacgat atatccatga acaagtaacc caaaaaggat
     2641 acccgccgac tgtccgtgaa atcggggaag ctgttcagct ttcttctact tctactgttc
     2701 acggtcatct tgcacggctt gaaaaaaaag ggtttatcca aagagatccg acgaaacctc
     2761 gtgcaatcga gttgacaaaa caaggtttag aaaagattgg gattcgtcca acaactattc
     2821 cagtacttgg cgtcgtaaca gctggagaac ccattttagc agtagaggat gcttcagact
     2881 tctttccaat ccctcctaat ctttcttccg aagaaggcag tctctttatg ctgacaattc
     2941 gtggagatag tatgatcaat gctgggatct tggatggtga caacgtgatc gttcggaagc
     3001 aagaaactgc tcaaaatggc gatattgtca ttgcaatgac tgccgaggac gaagcgactt
     3061 gcaaacgatt ctataaagaa aaaaactttt tccgtctgca gcctgaaaac gacttgctcg
     3121 aaccaatcat cttagatcaa gtatctatat taggacgagt agtaggactt tatcgtagtc
     3181 atatctatta attgctacta ataaaagaaa actttttaaa aagagtttga gacgatggtc
     3241 tcaaactctt ttttcgcccg ggttcttctt ctttcaaatt tttatcactt ccctctttac
     3301 aaaccgaaca aatattcgta tactaaatat acgaacaatt gttcgcataa attaacgagg
     3361 tgagaattca tgaaatcaat gagacgtctt ggcttagtat taactgtttt gtttttaggt
     3421 attattattg gtaatttcgg catacgtcca gctttacttg tgtttgttcc gttatttact
     3481 ttgtggttca tgttgtggga tgaaaagaag taccgtcaat ctgagcggcg cagaattcat
     3541 gaagatcatt tctatcatga gccctactac agatccaggc aatcataata aggattgact
     3601 gctaattatt caaaagacaa gaagttaaac ttttacgggg gtgtgacaaa aatcggtcac
     3661 atcctttttt cgaataaacg gtgttctaaa gccagttttt cggtattaag tcaaattgcg
     3721 gaaaaagtga ttttttaaac ttctactggt ctttgcttgt ttccatttat aaaaaaatag
     3781 cgaccctcaa aagtcagata gagaatctga cttttgaggg tcgctttaaa atcgcttctt
     3841 taagaataac atcaagaata gcttcttttt tctgcttaat attccattaa tgtaatgatg
     3901 tcatatcctt tgattttgtc gcgtccatgg agatccatca attcgatcaa aaatgcgcag
     3961 cctacgacta caccgcctaa ttgttcgatc agttcgatcg tcgctttgat tgttcctcca
     4021 gtagctagca aatcgtcaca aatcagcaca cgttgacctg gtttaatggc atccttatgc
     4081 aatgtcaatg tatctgttcc atattctaat ccataagtca cttcgatggt ttctcgaggt
     4141 aacttccctt ttttgcggac tggggcaaaa ccgactccta actcataagc aacaggacat
     4201 cctacgatga atccacgggc ttctggccca actaccatat caattcgttt ttcttttgca
     4261 taatttacga tttgcttcgt agcttcccga taagcgtcac catctgccat cagtggggaa
     4321 atatctcgaa acacaattcc ttttgacgga tagtcgggaa tactggcaat ataatctttt
     4381 aaatccactc tttgtttcct cctaggttgt taaccatttc tttatggtag gaatatcgct
     4441 caaaagcaaa aattcctcaa ctttgatttt attgagccgc cgctggtata atctgctctc
     4501 agtcaaagga tgactttctg ggctagcgac tttttgtaaa acaccgttct ctattgtaac
     4561 aaatttcaat tcaaaaaaca cctgtatcat aaaaattaat aatttttcag ggatacgcaa
     4621 atattgagct attgctttta ttttatgacg tatatcaatt cgttcttgag aatggatcag
     4681 tttaaacaat tttgcgtact gttctcttgt gcctacccca ttcaaatagg cctcatcagg
     4741 cgaaatcccc atcagataaa cacgattgaa tgaataagac cgaaaaactt ctttcagatc
     4801 cgctaaatca tctggacaat ccataataac tagagagttc ggttttcttt tttcaattat
     4861 tgcctttaca gaatctagtc cttcgaaaac aatcgcagct tcctggataa tctcaggcac
     4921 gaatttcaac gtagaagaat caaatgctaa ataaaggcta ccttccgacg ttcggctctg
     4981 ttcacggaaa cgttttgccc gccaatcaaa tacttgcaga ccacccacag aaaaatcaga
     5041 taccatcagc tgcggtttct tacgcccgtt ccattcattg atcgaaagct ttcctaccac
     5101 atctacctga ttattcagca gttcttcttc ttgagtacca aaaccaaaag cgaccgcatc
     5161 aagctgactc gatgcattgg aaaggacaaa tttcagatgc tgttggtttg ctccgattct
     5221 tttgatattt tctgcttgga cttgtcgaaa taaaaactga ggcaaaggat tatccgtacc
     5281 aaatggcgcc aatagtttca gctcatcaat tcgctctact gttacttcat ttggcagcaa
     5341 tacttcatca attctcaact caggccctct catcaagtca atttgatgat cgactatata
     5401 ttggttcatc ttctcctgta gtatagtgac attttcactt ggcatcgtta aaccgactgc
     5461 tgcatgatgt cctccgaagt aagtaaataa atctcgcatc tggtcaagca tttcaaaaag
     5521 attcaaggct tcaatactac gtccagatcc tttagctgat ccatcttctt ttaaagtaag
     5581 gacaagcgtt ggtttacccg tttcattcat tattttccca gcaacaatgc ccaaaacgcc
     5641 ttcatgccat cctcggttta ccaatagatg gatatgattc tccttattga ccatcgctaa
     5701 tgcttcttgt gttatctgct ctacgattgc ttttctttct tcattgatct cattcaattt
     5761 ttttgcttga acggatgctt cctcttcatc aaacgtcgca agtaacgaga cggcaggacg
     5821 tggatcgccc atccgaccga ttgcatttag tctgggagca atcgaaaaac cgatcgttgt
     5881 ttcgtctgcg tccctcattt ttacgccgct ttcttcaaat agcgcctgaa gtcctatccg
     5941 ttctgaatga tgaatggcat tgattcctaa tgaaacaagg attcgattct catcagtcaa
     6001 tgaaactaaa tcggcgatcg ttcctatcgc tactaaatcc aaaaattcta caggcggttc
     6061 ttccaataat gcagaagcta ctttgaatgc tactccgact cctgccaaat ctggaaatgg
     6121 atagtgcccc gctggatgac gagggtgaac aatcgcataa gcgtctggta aattctcagg
     6181 tagttcgtga tgatctgtaa tgatcacgtc tacaccagct tgctgagcgt atgctaccgc
     6241 atcatttcct gctaccccgt tatcaacagt gatgatcaac tggattcctt cttcgatctt
     6301 ttcttggtat acagattggt ttggtccata cccatgctca aatcgatttg gcaggaatac
     6361 ttctacttct gcaccaagta attccagtgt ttctttcatt accgttgcac tggtgatccc
     6421 atctgcgtca taatcaccgt aaacgaggat tttttctcca ctgattacag cttcttggat
     6481 tcggctgatt gctttatcca tatcgtgcat cagatacgga tcatgtaatt cttgttcctt
     6541 tggatgtaaa aatcggttga tatccttttc ctcatggtaa cctctttgcc acagtaactt
     6601 accgacaaat ggagataatt tcagttcacg gatcatttgg agaaaggatt cagaaggctc
     6661 tgtctcgctt aacttccaat caaaatttgc ttgtctcact ttctcactcc taacttagtt
     6721 attatagcaa aggaaatcag caaaaaaaag cagaaagaaa gaataaaaac agatcagatc
     6781 cgctagacag atgttcagca ggacctgatc ttttgtacga ccatttatga aatatcccta
     6841 ttagtcaaaa taattgaagc tttgtttggg cgattgagtt ttttgttctt ccggcgcttt
     6901 caattgactg atttgtgcgg ttttcgcttg taactccgcc tgataagcag cttccaactc
     6961 cgcacgttcg tttctaaact cgcgttgctg ttcttctttt gcttcttcaa ttttcttttg
     7021 aagttctgtt tgatattctg acatttcctg agtcagctgt ttgatttgct ttttttgctg
     7081 ccatagtgtt gccgaagcag tcaaaaatac aatcagtgca ccaatcagcg cagaaccgat
     7141 gatcactaag atcaatggcg cagaaaagga agtgaagcca aaacttacag gaacattttt
     7201 attgttcaat acagcaaaaa gaacaataat caaaactaaa acaaatccaa gaatcacatt
     7261 gctttgcttt ttcaattcct tcacctactt tttgttaaaa attccgctgg ctaaataatc
     7321 accaatcgtt ggaaacagcg tataaaattt tgatgcaact tctaaaataa acggttgatt
     7381 gatttcccgt tttggatgtc tcatattgcg gacgatcatt tttgccaact tggcaggttc
     7441 taaaacgatt tgtccgactt tttccaaata gcttccgctt ggatcagcct tatcgaagaa
     7501 atctgtctcg attggacctg gattcactgt cgtaacagct acgccaagtg gtttcaattc
     7561 taatcgcaaa gcgttggaga agccaaggac tgcaaatttc gtggcagaat aaaccgttga
     7621 ttttgcagtt gccatttttc cagccataga cgcgatatta atgatatgac cttgtcttct
     7681 ttctgccata tcgatcgcaa atttttgtgt caaaaccatc attcctaaga tgttgacttc
     7741 aaacatatcg tatgcttttc caaggtcgaa tgtaaggaag tcttcgaaaa tcccaaaacc
     7801 cgcattgttt accagaatat cgacgcgccc gacttcttcc atcacctttt catataattc
     7861 gtccacgctt tcaggattgc tgacgtctac cttgaaagca taagcctctt tgccgctcaa
     7921 gcgtctgcac tcgtctctga caccttctac aaatgccatt cttcgtgcgc aacttataac
     7981 gattgctcct tgctttgctg cttcataaca gatttgtgcg cccagaccgc ctgaactacc
     8041 tgttactaaa acaactttat cttctaaatt catgcctctt cctcctcgcg aaatggaatc
     8101 tcaatgctat caaaatcttt catgatcgtc gtgttttcaa acacttcttg tgcttctttt
     8161 tcaagctcta aagctgcttt tcctaaatat ctcgcactga tatgagtaag tagcagccgt
     8221 tttgcctgcg cttcttttgc aacttcagca gcttgatgag tcgtggaatg gaaatagttg
     8281 tgcgccattc ttgcttcatc tttattaaat gtgctttcat gtaccagaat atcgctattt
     8341 tccgcaagca caacggaatt atgtgttttt ctcgtatcgc ctaaaatagt cacgattcgt
     8401 ccttttttat ctggacctac gaaatctttt ccattgatcg tccgcccatc ttctagttgg
     8461 atcgtttcac cttgcttcag tttgccgtac agtggtccag ctggaatacc taattctttt
     8521 agacgatcca cctgcaattc tcctttatga tcatgttcaa ccacacgata accaaaactg
     8581 tcgatcccat gatttagttt ttttgtataa acagaaaatt gctgatcagt aaaaatcggg
     8641 gctgtttcat ttagctcaat gaatttcagc ggataactta aacgcgtttg cgaaatacct
     8701 aaagagactt ttatgtattc ctctatccct tttggcccgt aaatctctaa tggcgtatcc
     8761 ccaccttgaa atgaccggct gctgatgagc ccgggaagtc caaaaatatg atcgccgtgt
     8821 aaatgtgtaa taaaaatttt accgattttt ctcggacgaa tagtcgttcg caaaatctgc
     8881 atttgcgtgc cttcgccaca gtcgaacaac caaacttcat tgcgctcgtc taaaagtttc
     8941 aatgctatac ttgtcacatt tctatgtttt gcaggaacac ctgcacctgt tcctaaaaat
     9001 tgtaattcca taatctacct gactttcttt aagttcctct ttaattttag ggtaaaaaga
     9061 agggataatc aaccgtaagt cgagaatggg ttcaaattaa aaataacgtt ctaaagcgat
     9121 agcgttttct ttgaaaatta ctataaaaac agcagcgaac ccgtttgaga tcctctgctg
     9181 ttttttatta atttgaagat ccagaacttt cattgtcgtt ggaagtttgc ggatgtttgt
     9241 ccttccaagt cttttgtgca gcttctttcg catgattttc agcttctttc gcatcatgca
     9301 catctttttc gacatcttca taatccaagc gggtaatttc tccgcctaat tccatcatta
     9361 ccaattgatt cagtgggcga ttgtcctctt catcagcaat caagatcagt cctgtagctc
     9421 cttcaccgat tttatttcct acaaagtcga acacggtctg ggcatctttt atttctttgg
     9481 catcttgtgt cgcaccgatc attcctccgg caaaccatcc taataaaatc cctagcggac
     9541 cacctaatac accaaccaac attccgatta atccacccgt agaagatttg ttattaccgg
     9601 taaagtcgat aaaatcttct attttgaatt gatgtgtccc attaggatca tggctgacaa
     9661 ctgccatctg ttctccttta atcgaacgaa cagcatgtaa ctttttgatt tctgaaaatg
     9721 cctgatatgc ctggctttct acttgaaaat ttaaaatgat tactcgtttg ctcattaaaa
     9781 acgccccttt cataccttct tgttatttat tttaccttta attgtaaaat aagaaaagaa
     9841 aagcactctt tttttccaat aaaatagggc tgtgacaaaa gtcgtatcac agctcctttt
     9901 tccgaataaa cggcgttctt gaagctgatc acttctgtca caacctccct taaatctgaa
     9961 tctatatttt ttggtatttg tttttatttg cttgcctatt cgacaaattc aaattcaaac
    10021 tcaccgatac gtacaaggtc gccatctttc gcaccgcgtg cccgaagagc ttcatccaca
    10081 cccataccac gtaattgacg agcaaaacgc atcactgttt catcatgatc gaaattcgtc
    10141 atttggaata atttttcgat cttctcacca gataagatcc acgttgcatc tgaatcacga
    10201 tcgatttgga actcaggacc ttctggattg aatccatagt gtacagtttc ttcttccagt
    10261 tcttcttcgt acaatgggaa ttctggcgtt acttctaaca aatctgctgt agcattcaat
    10321 aacgcgtcca atccttgtcg agtcactcca gaaattggaa atactgggat gtcatcagca
    10381 aattcatctt ctttttcctt gttcagctgt tctttgaatt tcactagatt ttccggtgca
    10441 tccggcatat ccattttgtt tgccacgatg atttgcggac gctctagcaa gcgtaagtta
    10501 taagtagata attctttgtt gatggcaaga tagtcttcat aaggatctcg tccttccatc
    10561 ccactcatat cgatcacatg taaaattact cgtgttcttt cgatatgacg aaggaattgt
    10621 gtacccagcc caacaccttg cgaagctcct tcaatcaagc ctggcaagtc tgctgcggca
    10681 aaacttctgc catcacttgt agtaaccatt cctagattag ggacgagcgt cgtgaaatga
    10741 taagcgccga tttttggacg agcagatgaa ataacggata gtaaagtcga tttcccgaca
    10801 gatggaaaac ctacaagtcc aacgtctgcc aatactttca attctagttc gatttttcgc
    10861 tcttgtcctg gttcgccgtt ttcagcaatt tccggtgcag gattccgagg agaggcaaaa
    10921 cggatattcc ctcgtccacc gcgtccacct tttgccacaa ctagtgtttg accattttca
    10981 attaaatctc ctaaaagagc accagtctcc gcatctcgga cagtggttcc ttgtggtact
    11041 ttaacatagg tatcttctga accacgaccg tgcatccctt tactcatccc attttcacct
    11101 ggctgcgctt tgaaatggcg attgaaccga aaatccatca atgtacgtaa cccttcatcg
    11161 acgatcaaga tgacatcgcc gccacgacca ccgtctccgc cagccggtcc gccgtcagga
    11221 acgtattttt cgcgacgaaa tgcaaccatt ccgtctccgc ccttgccagc tttcacatcg
    11281 atcgttactt gatctaaaaa catggacata attaagtcct cctattattc atttatttat
    11341 ttgactgcct gaatttccac aataaacaaa agtcttactt attttatcgg tgaaatctga
    11401 ttttgtctat catttcagca aaaagattgt ttaccttctt ctttttttat catttggtaa
    11461 ggtttccaac cttttttctg ctaccaagta taattttttg acaaaatatt ctttgcgtag
    11521 cagaataaca gtgtattaat tgtattaatt gaggatgccg tttcacagca cccctaataa
    11581 aggaggaact tttgatatga cagtaaaagt aggtattaac ggatttgggc gtattggccg
    11641 tctggctttc cgccgcatca aagaagtctc agatgatatt gaagtagtag caatcaacga
    11701 cttaacaagt ccaactatgt tagcacaatt attgcaattt gactctactc atggtactta
    11761 tcctggcaca gttactgcaa cagaagactc aatcgtagtg gatggcgaag caactcgtgt
    11821 ttatgcagaa cccgacgcaa gcaaaatccc ttgggcaaaa gaaaacggtg tagatatcgt
    11881 actagaatgt actggttttt atacatctga agaaaaagca aaagcgcatt tagatgctgg
    11941 tgtcaaacga gtagttattt ctgccccagc tggtgctatg aaaaccatcg tctataacgt
    12001 caatgatgat acattagatg aaaacgacaa aatcatctca gcaggttcat gtacaacaaa
    12061 ctgtttagca cctatggctt atttcttaaa taatgaattt gggatcgaag ttggtacaat
    12121 gacaacagtt catgcctaca cttccacaca aatgctctta gatggacctg taaaaggcgg
    12181 taatttgcgt gctgctcgtt cagctgctga caatactatc ccacattcta ctggtgctgc
    12241 gaaagcaatc ggcttagtta tccctgagct acaaggaaaa ttacaaggac acgcacaacg
    12301 tgttccagtc gttgatggtt cattaactga attggtttca gtattgaaaa caaaagtaac
    12361 tgctgatcaa gtaaacgaag caatcaaaaa acacacagtt gacaatcctt cattcgggta
    12421 tgatgaccgt caaatcgttt ctagcgatgt cattggaaca actcaaggtt cgatctttga
    12481 cccaacgcaa acagaagtaa caactgctgg tgatttccaa cttgttaaaa ctgttgcatg
    12541 gtatgacaat gagtatggat ttacttgcca aatgattcgc ttactagaaa aattcgctaa
    12601 cttgtaattt gatagatcaa tcgataaaag aagcctttga ctggatccag tcaaaggctt
    12661 ctttcttttc atcccctact tttaaactcg ttcaatgaac atattggctt aaaaattgtt
    12721 ggactacttg ctgatatttt tcaggatctg tcttgtatgc ttccgcatgc tcggctcctt
    12781 ttacaacata cttttctttt ggtcccttcg ttgcacgata gaccttatct aacatttcaa
    12841 atggtacaaa tgtatcttcg tctccatgta taaagagcat tgggcgctgg tttttcttca
    12901 attgttccac tgcatttgct tcaccgaaaa agtagccagc acggactttt gtcactagac
    12961 tcgttacttg cataagcgga aatgctggaa gactaaacat atcgtctagc tgataagcaa
    13021 gctcatcatg aacggaagaa taaccgcaat cttcaatgat tgctttcaca ttatctggta
    13081 gtttttctcc gctagtcatc ataactgttg ctgctcccat gctgacaccg tatagaacga
    13141 tttcttgcga ttttccattg ttttctagca ctttgtttat ccactgtaca tagtctttac
    13201 gctctggcca tccaaatcca atgtaatccc cttcgctttt tccatgtcct cttgcatcag
    13261 gaacaaggac attgtaaccc atatcatgaa acatctttgc gtaattggtc atcgtttcag
    13321 cgtttcccat atagccatga gccacaagag ctgttttttc acttttcgtt tcagcaggaa
    13381 gataaatcgc tgataatttc agaccgtctt ttgaagtgat ggtccaatcg cttcggtttt
    13441 cttttgaact aaaccattta tgtgcatccg tttctttgga tgtctgtgtt gtaccaggtg
    13501 tatcttcgtc taaaaagtct ttctcagaag gcacaacagc ataattataa aaataattcc
    13561 ctgcaaacac taacgcaaca atcagagcta aagcgacgcc taaaaggatt ttcatccaaa
    13621 gtttcataaa tcatccatct catttctctt ttttcatata accttgaatt agtataatca
    13681 aagaatctct actatgcaat gttcattttt ataac
//
LOCUS       DAXLPQ010000060        13710 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.060, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000060 DAXLPQ010000000
VERSION     DAXLPQ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.060"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            201..2672
                     /locus_tag="ACF3UO_002257"
     CDS             201..2672
                     /locus_tag="ACF3UO_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3658213.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2775..4511)
                     /locus_tag="ACF3UO_002258"
     CDS             complement(2775..4511)
                     /locus_tag="ACF3UO_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3658214.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4508..5212)
                     /locus_tag="ACF3UO_002259"
     CDS             complement(4508..5212)
                     /locus_tag="ACF3UO_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3658215.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5343..5846
                     /locus_tag="ACF3UO_002260"
     CDS             5343..5846
                     /locus_tag="ACF3UO_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFD3658216.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5806..6144
                     /locus_tag="ACF3UO_002261"
     CDS             5806..6144
                     /locus_tag="ACF3UO_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFD3658217.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6165..7583
                     /gene="ffh"
                     /locus_tag="ACF3UO_002262"
     CDS             6165..7583
                     /gene="ffh"
                     /locus_tag="ACF3UO_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFD3658218.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7695..8273
                     /locus_tag="ACF3UO_002263"
     CDS             7695..8273
                     /locus_tag="ACF3UO_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFD3658219.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8277..8798
                     /locus_tag="ACF3UO_002264"
     CDS             8277..8798
                     /locus_tag="ACF3UO_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFD3658220.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8877..9431)
                     /locus_tag="ACF3UO_002265"
     CDS             complement(8877..9431)
                     /locus_tag="ACF3UO_002265"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFD3658221.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9684..9959
                     /gene="rpsP"
                     /locus_tag="ACF3UO_002266"
     CDS             9684..9959
                     /gene="rpsP"
                     /locus_tag="ACF3UO_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFD3658222.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9971..10222
                     /locus_tag="ACF3UO_002267"
     CDS             9971..10222
                     /locus_tag="ACF3UO_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFD3658223.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10347..11138
                     /locus_tag="ACF3UO_002268"
     CDS             10347..11138
                     /locus_tag="ACF3UO_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658224.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11308..11829
                     /gene="rimM"
                     /locus_tag="ACF3UO_002269"
     CDS             11308..11829
                     /gene="rimM"
                     /locus_tag="ACF3UO_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFD3658225.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11819..12580
                     /gene="trmD"
                     /locus_tag="ACF3UO_002270"
     CDS             11819..12580
                     /gene="trmD"
                     /locus_tag="ACF3UO_002270"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFD3658226.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12716..13063
                     /gene="rplS"
                     /locus_tag="ACF3UO_002271"
     CDS             12716..13063
                     /gene="rplS"
                     /locus_tag="ACF3UO_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFD3658227.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13423..>13710
                     /locus_tag="ACF3UO_002272"
     CDS             13423..>13710
                     /locus_tag="ACF3UO_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658228.1"
                     /translation="MGKDKRIVWKDQSDLKIILTISQFIETYEIKSSREYQKQLSKNP
                     HSAPSMWFIINKYGSWNNLLNSIGIDNNGSKKWARMETDELIKVAQIFIDSE"
BASE COUNT         4570 a         2482 c         2808 g         3850 t
ORIGIN      
        1 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
       61 tagaaccctt tttttttgct atatgacagg aatgaaaggt gtttgcaagc ttaatgtgag
      121 gaacactttc catatctgtt ctatactgga taggagaagt ttggaaatat ccagaaaacg
      181 aaatcaatcg aggtagccac atgaagaata aatggataaa tcgaagtaaa aaaaagaaag
      241 taacacaaag atcatcagat aaagtcatcc gtctttttcc atcgtataaa gaaggattaa
      301 cggcagatca agtcaaggaa cgaatagaaa aaggtgcagc aaataattca gtcgatccca
      361 cattcaaaac aaatcagcaa atcgtattgg aaaacatatt tacgtatttc aatttgatct
      421 ttcttatctt agccattttg ctttgtttag tagaatccta taagaacttg acttttttac
      481 cagttatcat agccaataca ggaatcgcca tttttcagga aattcgatcc aaaaagatct
      541 tggacgaact aaatgtttta aatacagcaa aagtcaatgt catacgagac gggatagaac
      601 aaacaataga tatagaagac cttgtaatag atgacattgt tattttagag actggatatc
      661 aaattccagc agatgcagag gtcgtggaag ggaaactgca agttaatgag gctttattga
      721 caggcgaagc agatgaaata accaaagaaa taggtgatcc attaatgtcc ggcagtttca
      781 ttgtttccgg aaaagcttac gcccgattag acaaagttgg agcagattcg tatatttccc
      841 agctgacagt caaagccaag acaatgggag aaggagaaca gtcggagatg attgcttctc
      901 ttaatcaatt gatcaaatgg attgggatca tcattattcc tatcggtatc ctgctttttt
      961 ctcaaagtta cttttttaat ggaaacacga tcaaagaaag tgtcgttgca atggaagcag
     1021 cattgatcgg tatgatacct gaaggactgt acttgctgac gacgattgca ttagcattaa
     1081 gtgcgactaa actagcaaag caaagagttc ttttacacaa tatgaaaagc attgagacat
     1141 tggcaagggt aaatgtcctt tgtgtagata aaacaggaac gatcacagaa aataaaatgt
     1201 ctgttcaaaa aatgatcgtc tctaaaaaac aagaaataat cagtcagtca gatcaattgg
     1261 aagcatgcat tgctgactat gcaaaagcga tggcaggaga caatgcaaca atggaagctg
     1321 ttaaagcata ttttacaaaa accactgatc aatcctatca ccatgttatt cctttttctt
     1381 ctgtccaaaa attcagcagt gtagcgttgg cagacaaggt gtatgtttta ggagcgcccg
     1441 aaatggtttt gcgcgatcaa ttgccggaat atgcggaaga gtttgtttct ttcgctgaaa
     1501 aaggctatcg cgtgttggtc tttggtgtgt acgatgggat tcttgaagaa ccagtattga
     1561 cagaagcagt cacaccatta ggctatattc tgattgctaa tcctatcaga aaagaagcaa
     1621 gagccacatt tgattacttc aaaaaacagc aagtagccat caaagtgatt tctggagata
     1681 atccgctcac cgtatccaat gtagctgtcc aagcagggat ttcacatgct gatcagtacg
     1741 ttgatgcatc taaattatca gaagaagaat atgaagcagc tgtcgaaaaa tatacagttt
     1801 ttggacgcgt caagccagaa caaaagaaaa tcttcgttca attgataaag cgtaacaata
     1861 cagtagctat gacaggtgat ggcgtgaatg atattctagc catgaaagaa gcagactgca
     1921 gtatagcgat ggcttccgga aatgaagccg ccatgcaggc ctcacaagtg gtcttacttg
     1981 attctgactt ttcacgcatg ccagaagttg ttgcagaagg acggcgcgtt gtgaacaata
     2041 ttgagcgatc agccagcttg tttttagtga agaatatttt ctcctttttg ctctcactgt
     2101 tttcagtgat ctttgctctg acctatcctt tagaaccatc acaaatcaca ttgattagtt
     2161 tgtttactat cggacttcca tctttcttgc ttgctctaga agaaaacaaa aagcgaatca
     2221 gagggaaatt catcatgaat gtgatggaaa aagctgtgcc aggtggacta acagatatga
     2281 tcgtagtcgg tgcgttggtg atctgcgggg tgactttgaa tctaaataaa acagatgttt
     2341 ctacagcatc taccatgctt ttgattgcag tagggttcct cgttctctat aaaatctgtt
     2401 caccgctgaa taaattcaga agtcagatca ttcttttctg tgctagcggt aacttttttt
     2461 cggtcatctt tttgcataag ctgttttcaa tcaccggtat ctcagctgta tcacttttgc
     2521 tgttgagcat tctatttttc tcggcagatt cgatttttag gcatttgacc acattggtag
     2581 aatatttgtt tgaacgtaaa aatgaaaaag agcaaaagcc gtttagtcgc gtagctaaaa
     2641 aatttctatc gatatttaaa cgagaaaatt gacgaaaagt atctcaaaaa agagtaaaaa
     2701 agaacaacca ctcgtgtatc tttcgaagca ggatgagtca tccaacttta aaacgcacga
     2761 gcagttgctc ttttttacat tttcggaatg gtaacggtga aagtcgaacc tgttccaaga
     2821 tgactgtcta cagtaatcgt accattaagg agttgcacgt agtcttttac aatcgctaac
     2881 cctaatccgg tcccgcctga atgtcggctt cgcgccttgt ctacgcggta aaaacgctca
     2941 aagatccgtt cctgatcctc aatgtcgata cctataccaa agtcttggac agaaaacgat
     3001 agatcatctg ttgcctgata gcggataata atctcgctgt cgctttttga atattggaca
     3061 gcattttcaa tcagattttt gataattgga taaaggatat ctgttttagt agtaaatggt
     3121 tcgttctttc caatcaatcg aatcgtcaac cgtttctttt cgatgattgg ctgataattt
     3181 tgaacgattt gctggaaata aggttctgta taaattgtct ggatctcgta agaattctcg
     3241 ccatcttttg acagctggat gatttcccga atcagtttat ctaaccggat cgcatctttt
     3301 tgcatgatct caagaaaaga agtcagagtt tgcgggtcat cttttgcacc atccagtaaa
     3361 gtctcggtaa aaccaatcag tgaagtcaca ggagttttta attcgtgaga gacgttgcca
     3421 acgaaatcct tttgtagctt ttctaaacgt cgcactttcg ttaagtcata cgccacccct
     3481 agaatctgtc cggtaccttc tgaattagta aagtagcgca aactcaagtc taatgtctgc
     3541 cgaccttctg taagggtgat ctcctgatgg atcagcggat gctcaggagt cacttgatga
     3601 atcagctgaa tgagttttgg ctcttgaatg acttctgtgt accgctgttc aggttgatag
     3661 cttaccacgt ttaaatgtag ctgcatcttt ggattaagca gtagtaaacg agaatcagca
     3721 tcatcaatca ggaatacgcc aatcatcagt tcgttcagta acgtatataa ttgctcttct
     3781 gtggtagtac acgcccgata catcttactc atttgttcgc tcaacgcatt aatcgtctga
     3841 tacaattctt cccattgatc gggtgtttgc atgattactt ccgcctgatt aggattttgc
     3901 accatttttt ttagtacggg cagcacggtt ttcaatggct ggtttttttg atagatcaga
     3961 taatagatca ttcctgcaag aacaaggaag aaagacagaa agaagaaaaa gacccaacgg
     4021 cgaaaactct cagttctcgg taaaaaaacg cttgtcggtt ctgcgatacg taaaatggct
     4081 tctaactggc cacttttttt gactggtaat gcgacatata aaagatcctc attcaaagta
     4141 gtacttttgc gcaaagcgct acctaggttc ccaccattca atacggcttt gatttcggga
     4201 cgggagtttc gctgttcatt caatgtttca ttgtttgtgt caaataagat ctttccagta
     4261 gcatccatta aagtaatccg ttcgttcgac tgatggacga attcttccaa agcagttttg
     4321 ttttgcgctg cttggaggtt ttcgacatct aattgccgga tcagcagttg tgcttttttt
     4381 gtcaggtagc tttcttgctg ttccacgatc tgctgttgaa aataatggga aatcaattgc
     4441 cagccaccaa aaaacaaact aactaaaaga ataagaaaga agagacgttc ataaattttt
     4501 ttccatttca tcgtttgggt tcctgaaact tatagccaaa tcctctaata gtcaccaagt
     4561 actttgggtg ttttggatct cgctcgattt tttctcgcaa atgactaacg tgtacatcta
     4621 cgattcggct ttgtcctgcg aagtcaaaat tccaaatgcg gtctagcaat gtgtctcggt
     4681 cgatcacacg gtcttttcgt ttcatgaaat aaacaagtaa ttcaaattct ttcggtgtta
     4741 gttcaatcag atggtcgtct acggtcactt gataattggt caaatcagca gtgatttgtc
     4801 caatcgatag atattcaggc tcagcttcat cttttgattg cttacgaggt tcaattcgtc
     4861 tgaatattgc tttcatacgg gctaatactt cgcgaggact aaatggtttg gtcaaatagt
     4921 cgtcagcacc tatttctagg ccaatgatcc gatccacttg gtcatcttta gccgtcagca
     4981 tcaaaatcgg tgtttcattt ttttcttgac gcagccgctg agtgatctcc atgccatcca
     5041 tcgttggaag catcacatct aaaatgatga aatcaaatga ttgttctaat gctaattcta
     5101 atccttcgcc tccatctgtg gcactggtta ccttgtagcc ttctttttcc aaattgaacg
     5161 tcaagagcgt tacaatagaa ggttcatcat caacaactag tatttttttc attcaaatct
     5221 cctttaaata ggtttcattc tgtttatatt ttagcataga atcagtacaa agggctattt
     5281 tacaaaagaa ataaatggta taataggaag gcactttgct gaatagaaag gaagagcagt
     5341 caatgattgg aatcagtgca tgtttaggcg gtctggcctg tcgctatgat ggacagaaaa
     5401 aagaagtacc agaattgatg gaactagttg aaactggaga agctgtcatg gtctgtccag
     5461 aagtgatcgg cggattacca attcctagag atcccgctga aatcattggt ggaaatggat
     5521 tcgatgtgtg gaaagatcaa gcaaaagtat ggacgacaag cggcgaagat gtaacggaag
     5581 cgtacaaaaa tggcgcgatc aaagcctatc aaaaattgca ggaaaaacac attgatctag
     5641 tcatcatgaa ggaaaaaagc ccttcatgcg gaacccattc gatttatgac ggaagttttt
     5701 ccggaataaa aaaaaatggt gccggagtgg ctactgctta ttttattcag caaaaaatga
     5761 ctgtgctctc tgatgaagaa tggctgaaaa ctagaggtga gcagaatgga aatcgaaaag
     5821 accaatcgaa tgaacgcgct ctttgaattt tattcgacct tattgacaga aaaacaaatg
     5881 aactacatgg aattatatta tgcagatgat ttttcattag gtgagatcgc ggaagaatac
     5941 gaagtaagcc gacaagcagt atatgacaat atcaagcgga caagcaagat cttggaggat
     6001 tatgaaaaaa aactccatct tttttctaat tatattgttc gagaacaggt attggaaaat
     6061 atgactgcat atattacaga taagtacccg gaagataaaa aactacttga atatgtacag
     6121 caaattcaag caatcgaaga ataaataaaa ggaatgaaga aaatatggca tttgaaagct
     6181 taactgaacg tctccagcag gcgatgggaa aaataagaaa aaaaggaaaa gtatcagaag
     6241 ctgacgtaaa agaaatgatg cgggaaatcc gccttgcctt actagaagcc gatgttaact
     6301 tgcaagtagt caaagatttt actaagcgcg tacgcgaacg tgcggtaggg gcagaagtgc
     6361 tggaaagttt atcacctgca caacaaatcg taaaaatcgt tgatgaagaa ttgacgatca
     6421 cacttggttc tgaaacagca gagttaaata aatcaccaaa aataccaact gttatcatga
     6481 tggctggtct tcaaggggca ggtaaaacga cctttactgg taaattagcc aattatttaa
     6541 agaaaaatga aaatgctcgt ccgctcctaa tcgcagggga cgtatatcga ccagctgcga
     6601 tcgaccaatt gaaagtatta ggtcaacagc tagacgttcc tgtatttgat atgggaactg
     6661 aagtcagccc ggtagagatc gtccgtcaag ggatggagtt agcaaaagaa aagaaaaacg
     6721 actatgtatt gatcgatacg gcaggacgtc tgcatatcga tgaaacattg atggatgagt
     6781 tgaaacaaat caaagaattg acgcaaccaa atgagatttt gcttgttgtc gatgccatga
     6841 ctggtcaaga tgccgtcaac gtagctgata gcttcaacca gcaattaggt attacagggg
     6901 tcgtcatcac taaacttgat ggggatactc gaggcggggc agcactatcg atccgctcag
     6961 tgacaggcgc accaatcaaa ttcatcggtt ctggtgaaaa attgactgac ttagaagtat
     7021 tccacccaga tcgtatggct agccgtatcc ttggtatggg ggatatgctg acattgattg
     7081 aaaaagcgca gcaagactac gacgagaaaa aagcggaaga acttgcacag aaaatgcggg
     7141 aaaattcatt cgatttcaat gactttattg aacagcttga tcaagtgatg ggtatgggcc
     7201 cactggaaga tctaatcaaa atgatcccag gaatgaatca agtccctgga atcgaaaacg
     7261 tcaaggtaga tccaaaagat gttgaacgca aaaaagcgat ggtttattct atgacgccag
     7321 cagaaagagc aaatcctgat ctgttgaacc caagccgtcg tcgccgaatt gctgccggtt
     7381 ctggaaacag tgttgttgaa gtgaatcgaa tgatcaaaca attcaaggaa tcaagaaaaa
     7441 tgatgcagca aatgtccaaa ggggatatga acatcccagg tatggaccaa atgtttggtt
     7501 caggcgtcaa aggaaaacta ggcaaaatgg cgatgaatcg aatgatcaag aaaaataaga
     7561 agaaaaagaa aaaacggaaa taagatgaaa aaaacagctt cggtacagac tgaaaatgtc
     7621 tactgccgga gcttttctat cagcaatttt tattctttac taatacaatt actctaaacg
     7681 aagaggtggc acagatgaga tgtccgtgga gtgaacaaac agaaagtatg cggcaatatc
     7741 atgatactgt ctggggtgtt cctgaatatg atgaccaaaa gctgttccga aaattgatgc
     7801 ttgatattaa tcaagccgga ttgagctggc agacgatttt aaataaaagt gaagcattcg
     7861 atgaagcata tgatcgattc gatatcaaaa aagtcgcaaa ttatggagaa acaaaaatca
     7921 gtgaactaat ggaaaacaaa ggaattattc gtaaccgaag aaaaatcgaa gcagccgtcc
     7981 aaaacgccaa agcagtcttg aaaattcaag aagaaatcgg cagtttttca gagtatcttt
     8041 ggtcgttttc taatggaaaa atcgttgatt cttcttatca ttcacaagaa gaagtcccaa
     8101 caacaagtcc tctttcagat gaattagcaa aagatctaaa gaaaagagga tttaaattta
     8161 tcggaagcac aacaatctat gcttttttag aagctgtcgg gatcatcaat gatcaccttg
     8221 acagttgttt ccgcaaagaa gaggtcgtac gtatcggcag aaagggcgaa taaagcatgc
     8281 gaaaaatcat attttatggt gctataagtt tagatggcta tttggcaacg aaaacggatg
     8341 atcttcaatg gctttttgac actccaacag gtaagcaaac tacttatgaa gctttttatg
     8401 aaacaatcga tacgaccatc atgggcagaa aaacttatca ggaagcaaaa aaatatttgg
     8461 agaccgaagc aatttatcca gagaaaaaga atttcgtttt ttccacccac gcacaattac
     8521 aattgccaga tgctgaggtc gtaaacgaag atcctgttgc ttttctaaaa aatctacaaa
     8581 tgacagaagg aaaagatatc tgggttgtgg gtggcggtcg attgatcaaa ccgctattgg
     8641 aacatcaaat gattgatgaa tggtatatcc agattacccc tgtattatta ggggacggga
     8701 ttcctttatt ccaaaaagga acatatgaag cgcgttttga aatgctagac acgacacgat
     8761 tcggtgaatt tatcgaattg cattatgtac gaaagtagaa gtaaataaaa taaaaaaggc
     8821 aactatatgc agaaatgtcc tgtacatagt tgcctttttt attaccgtta tgctttttac
     8881 tctgttaatt tgttagaaaa atctagatac gcatctaaaa tcgtttggaa gaaacttaat
     8941 gttccttcaa cgatattacc attttcatca attagattcg caacgtttcc gatatatgct
     9001 tccggttgct gcaaggttgg cacattcaaa aagacaagtg attggcgtag atggtggttt
     9061 gcgccaaagc cgccgatccc acctggtgat gcagtaacga ctaaacctgg tttatgatcc
     9121 caaacactgt gtccataagg tcttgagcct acatctaaag catttttcaa tactgctggc
     9181 acagaacggt tgtattcagg agtaacgaaa acgacaccgt ctagtcccct cacttcctca
     9241 cgaaaacgag tccattcagc aggagcctgt tctggagttt cgagatcctc attgtaaaat
     9301 ggcagatcat cgatttttac aaatacactt tcgtaccctt caggaagcaa tttcgcaaaa
     9361 gcttctgcta cttttttgtt gtaagaatct tttcttaaac taccaataaa aaatccaatt
     9421 ttttttgtca tacgattttt cctccttcaa actatctata ataatcttac aaaagataag
     9481 taactggagc aaataaaaac acttactgac aaaagctaca tagaagatag attacttatt
     9541 tttaacaaaa aagaagtcta aaatcttcta ttttctaaaa aaaatcgaat ttaatcaagc
     9601 tgtaaagaaa aaaagcttta cagggtaaaa aaaaactgtt acactacatc ttgtgaataa
     9661 aacaatggag gtggaaataa ataatggcag ttaaaatccg tttaaaacgt atgggttcta
     9721 aaaagagtcc gttttaccgt atcgtcgtag ctgattcacg ttctcctcgt gatggacgtt
     9781 tcatcgaaac tgtaggtact tacaatcctt tgaaagaccc tgcagaagta gttttaaaag
     9841 aagacttagt tcttgactgg ttatcaaaag gtgcacaacc ttctgacact gtacgtaaca
     9901 tcctttcaaa agaaggcgtt atgcaaaaac accacgaagc taaattctca aagaaataag
     9961 gtgaccggat atgaaagatt taagcgactt agtcttaaca atcgttcgtc cgctagtcac
    10021 ttatcctgat caagtcaagt tagacgtcgt agagtcgaaa gacttttacg agtacaatct
    10081 aacagtggct cctgaagata ttggccgtat cattggaaaa caagggcgtg ttgctaaagc
    10141 aatccgcaca atcgtttacg gtgttcggat caatgcaccg aaaaaagtgc gtttgaatat
    10201 catcgatgat aaggaaaagt aaataaacgt gctgtactcg aattttcgag tgcagctttt
    10261 ttgttttttt tattaattga agaaatgatt atttggcaaa acaagcaaga aagcgtatcc
    10321 ttataggagg agggagtgaa cagccaatga gaaagaaaat gttatttatt ccatttgctc
    10381 tattgttaag cgcttgtagt tcggttactc aagaatcaga caatacacat ctatcaagca
    10441 gtatatctga aactgttacc agtccagaaa aaagtagtac caaaacggct tccaccactg
    10501 aacaaacaat ggctacctca aataatgaga aaaagactgc tttagaccag ttgaaagaac
    10561 aacagccaaa tgttcccatg cctctagatg taccagtctc ttcaggctat ctcaatatcg
    10621 cagcgacaca tacaaagcaa ggttattcta ttttatatta cagaacagat cgtcccctcg
    10681 ggttgaatgc tgacgaattg aatcaagaaa cgcctattgc aacctatcta tatcaatatg
    10741 ggtttgcttc tagtcaagaa acaatccaag ttttgcagcc atttgagatc gacacaaatg
    10801 gtcagcaagt ggacttaggt tctcgaatca cagggtatca gcaaggtgca gcaggttcaa
    10861 gttttcttga atggcaagaa ggaaactggc gtattcgaat ccgtgggaat aatatagaag
    10921 gccaagatcc cttactatta gctaaagaaa tcgtagctta tttggaagaa aacagtctac
    10981 cagcacctga acaatttggt aaaattactg ttgatatggg tgatacgacg aatcgagccg
    11041 tagaagtaag ctggcaagaa ccgaaaaatg cctatacgat cactcatcaa gatcctatgt
    11101 ctgcgttgaa gatggcagtt tctatgaaga ggttgtgaaa tcagcgcgct gatctgagcc
    11161 catcatttaa ctccaagtca caggaagtaa tcaaaaatag cacgccgcat ttttgcataa
    11221 ttttggctta ataccttaaa agaaaactag aattgcctct tcacacatgc taaaataaaa
    11281 cagacaaaaa agaaatgggg atataagttg actgaatact tgaatgtagg aaaaatcgta
    11341 aacacacaag gtatcaaagg cgaagtccgt gttatctcaa caacggattt cccagaagaa
    11401 cgttacaaaa aaggaacggt gctaacacta ttccaagacg gaaaagcacc tgtggaatta
    11461 acagtcaaaa gtcatcgcaa acataaaaat tttgacttat tgagttttga aggacatcct
    11521 tctatcaatg atgtggaaaa atatcgggat ggcatattaa aagtgtcaaa agacaactct
    11581 gtagatctag ctgaaaatga attctattac catgagatca tcggtctgca tgtattagaa
    11641 gatggaactg agttaggtaa agtaaaagaa atcttgtcac caggtgccaa tgatgtttgg
    11701 gtcgttcaac gtccgaaaaa agctgatata ttgcttccat atatcgcttc tgtcgtcaaa
    11761 gaagtcgatt tagaagctgg agtggtccgt gtagaaattc cagaaggact gattgacgat
    11821 gaagattgat gtattgactt tatttccaag aatgtttgaa ggtcctatgg gggaatccat
    11881 catcggtaag gctgtagata aaggattatt agatatcaat atctctaact tccgcgatta
    11941 ttcagataac aaacatcaga cagtagatga ttatccatac ggcggtggag caggtatgct
    12001 gctcaaagtc cagcccatct atgataacat ccaagccatt gaaaaagctg caccggatgt
    12061 caaaaaaaga gtaattcttc ttgacccagc tggtaaacga ttcgatcaga aaatggcaga
    12121 agaattttca caagaagaac acttagtatt catttgtggt cattatgagg gatatgatga
    12181 acgtatccgc acattagtga cagatgaagt ttccttagga gattatgtcc ttactggggg
    12241 agaattaggt gcgatggtca tgatcgatgc aacagttcgg cttttgccag atgtgttagg
    12301 gaatcagact tcagctcaaa cggattctta ttcaaccggt ttattggaac atccccaata
    12361 tactcgcccg gcagaatata aagggatgaa agtaccagaa gtattgacaa atggaaatca
    12421 taaattgatt gaagaatggc aattaaaaga atcactaaga aggacctatc aacgtcggcc
    12481 tgatcttttg gaaacacttg aatggacacc tcaaatgacg aaatttttag aagaaatcaa
    12541 gaaagaagaa caagaaaaaa cagcagatga agccaagtga ctttttctaa aatcttcttt
    12601 acagtaggtt gataatatgt tagtatttta tggtgagtgc aaaagcactt aactattacg
    12661 atattccgct gtgagaaaag ctcataagaa tatttggaat aaggagaaga aaaccatgaa
    12721 tccattaatc gaagaattaa caaaagaaca attacgttct gacatcccag cgttccgccc
    12781 tggtgacact gtgcgtgttc acgcaaaagt tgttgaaggt actcgtgaac gtatccagtt
    12841 atttgaaggt gttgttatca aacgccgcgg tgctggaatc agcgaaactt atacagtacg
    12901 taaagtttct aacggagtgg gcgttgaacg tacattccca ttgcatacac cacgtgttgc
    12961 aaaaatcgaa gtagttcgct acggtaaagt acgtcgtgca aaattgtact acctacgtgc
    13021 attacacgga aaagctgctc gtatcaaaga aatcagaaga taaacacgga aaacttcctt
    13081 ggaaatctga aatctgtgaa aagtccttgt atatcaagga ctttttcttt tttctctatc
    13141 acatttttaa tatgttttgg gccttttttt ctaatgttct ctcaaattgt cctgaatctc
    13201 ccaatattga ctactattat cgtcaaaata ccgaaaaaat tagtagtcat tttgacgaca
    13261 aatttaatac gaaaaatacc taaacactta ccgaatttag caatttttga acccgagttg
    13321 ctaaaaaggt tgaatgcttt cgaaaaaagc aaaacatata ccattgtgct aaaaagttta
    13381 tgtgataggt ttctatttaa ataattttag gagttttttg taatgggaaa agataagcgt
    13441 attgtttgga aggatcaaag cgatttaaaa attatattaa caattagtca gtttattgaa
    13501 acttacgaaa taaaatctag tcgagaatat cagaaacagt tatcgaaaaa tccacattca
    13561 gctcccagca tgtggtttat tattaataaa tatggctcgt ggaataattt gctgaatagc
    13621 attggaattg ataataacgg atctaaaaaa tgggctagaa tggagaccga tgaattaata
    13681 aaagtggcac aaatatttat tgattcagaa
//
LOCUS       DAXLPQ010000061        13428 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.061, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000061 DAXLPQ010000000
VERSION     DAXLPQ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.061"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..306
                     /locus_tag="ACF3UO_002273"
     CDS             <1..306
                     /locus_tag="ACF3UO_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3658229.1"
                     /translation="HFARREKKLYRSLYLEEYGGGKEMQNFSYTYFVNTVKRDPAYVN
                     LSEEQIESLYNGTWIIATGIAALMSSSIIHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(484..924)
                     /locus_tag="ACF3UO_002274"
     CDS             complement(484..924)
                     /locus_tag="ACF3UO_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFD3658230.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLSGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            1082..1846
                     /gene="map"
                     /locus_tag="ACF3UO_002275"
     CDS             1082..1846
                     /gene="map"
                     /locus_tag="ACF3UO_002275"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFD3658231.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            1878..2801
                     /locus_tag="ACF3UO_002276"
     CDS             1878..2801
                     /locus_tag="ACF3UO_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFD3658232.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            2877..4016
                     /locus_tag="ACF3UO_002277"
     CDS             2877..4016
                     /locus_tag="ACF3UO_002277"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFD3658233.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            4009..4809
                     /locus_tag="ACF3UO_002278"
     CDS             4009..4809
                     /locus_tag="ACF3UO_002278"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3658234.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            4809..5636
                     /locus_tag="ACF3UO_002279"
     CDS             4809..5636
                     /locus_tag="ACF3UO_002279"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3658235.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            5641..6348
                     /locus_tag="ACF3UO_002280"
     CDS             5641..6348
                     /locus_tag="ACF3UO_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3658236.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            6448..7314
                     /gene="rfbA"
                     /locus_tag="ACF3UO_002281"
     CDS             6448..7314
                     /gene="rfbA"
                     /locus_tag="ACF3UO_002281"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFD3658237.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            7328..7900
                     /gene="rfbC"
                     /locus_tag="ACF3UO_002282"
     CDS             7328..7900
                     /gene="rfbC"
                     /locus_tag="ACF3UO_002282"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFD3658238.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            7922..8950
                     /gene="rfbB"
                     /locus_tag="ACF3UO_002283"
     CDS             7922..8950
                     /gene="rfbB"
                     /locus_tag="ACF3UO_002283"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFD3658239.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            9048..9899
                     /gene="rfbD"
                     /locus_tag="ACF3UO_002284"
     CDS             9048..9899
                     /gene="rfbD"
                     /locus_tag="ACF3UO_002284"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFD3658240.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            9933..11966
                     /locus_tag="ACF3UO_002285"
     CDS             9933..11966
                     /locus_tag="ACF3UO_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658241.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPAKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKIDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKEIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            12010..13290
                     /locus_tag="ACF3UO_002286"
     CDS             12010..13290
                     /locus_tag="ACF3UO_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFD3658242.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVCTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIATLLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         4120 a         2269 c         2844 g         4195 t
ORIGIN      
        1 cattttgcaa gaagagagaa gaagttgtat cgttcactgt acttagaaga atatggtgga
       61 ggaaaagaga tgcagaattt ctcttatact tactttgtga atacagtgaa acgcgatcca
      121 gcttatgtga atctttcaga agagcagatc gaatctttgt ataatgggac atggatcata
      181 gctactggga tcgcagcttt gatgtcttca agcatcatcc atccaactga tgaacagatt
      241 gaaaagatga tacaagacag tatagatgct atcttgaaat tcaaagaacc aatagaaatc
      301 gattgaatat actcaaaagt tccacaaatc agtagataac aagagatgtg tcaaaataag
      361 gaaaagttcg tttttcttac agcgtatgca tttttaactc ccgaagaact cttccatgaa
      421 tgcaatgaat aaaagagccg tacagattga ataaatctgg atggctcttt tattgcaagt
      481 atattaaatt tttgcgacta gttctttagc gaaagcttct aaattttcga tatcttcttc
      541 ttcagcattc agatccactt taacattttc ggctcctttt gatgcgcctg tttttgcaaa
      601 agcagcatcg aaatcatcca ccgatttgca gaattcatcg taaaaagtat caccagatcc
      661 gcagacaccg taaatttttc ccgatagatc caattcttgc aagtcttcat aaaagtctac
      721 gatctcatca ggcagatcgc catcatcgta tgtataagta gctactacgc aaatatctgc
      781 ctcctcgaat tcatctgcat ctacttgggt acattcgttg atttcgactt cgatatccag
      841 attttcaaat gcttctgcaa caatatcggc gatttcttca gtgtttcctg tcatgctagc
      901 atatacgatt tttgctaaag ccatgatgtg cctcctcgtt tataattatt taacaattat
      961 gaattatacc aaaacatcat tgaaaagaaa ataaaaccta gagacacctg gggaatgtca
     1021 tttggctaaa tgtatgccgc tatgttaaaa tgagagggat ttgtaaaaag gagacgaaaa
     1081 tatgattact ttaaaatcag cacgtgaaat tgaaatgatg gcagaatctg gagctttatt
     1141 agcagatgta cataaaaatc tgcgtgattt tataaaacca ggaatcacaa gttgggatat
     1201 tgaggtattt gtcagaaact atatcgagag tcatggcgga attgctgcgc aaattggctt
     1261 tgaagggtat gaatatgcga cttgtatcag tataaatgat gaaatttgtc atggattccc
     1321 tcgtaaaaag cctttgaaaa acggtgattt ggtaaaagtc gatatgtgta tcgatttgaa
     1381 aggcggcatt tctgattctt gttgggccta tgtagttgga gaatctacac ctgagatcga
     1441 ccgattgatg gaagtaacga agaaagcttt gtacatcggt attgagcaag cacaagtagg
     1501 gaatcggatt ggtgacatcg gtcatgctat ccaaacttat gtagaaggcg aaaatctagc
     1561 gatcgttcgt gattttattg gtcatggcgt tggtcctacg attcatgaag aaccagcagt
     1621 tcctcattac ggagaagctg gaaaagggtt gcggttgaaa gaaggcatgg ttatcacgat
     1681 cgaacctatg gttaataccg gaacttggaa aatgaaaatg gatcctaacg gctggactgc
     1741 gtatacaaga gacggcggac tttcttgcca atatgaacat acattggcta ttactaaaga
     1801 tggtccaaga attttgacat cacaaggaga agaaggcact tattgatcta tccagtcaat
     1861 aggtacggga gaggtacatg aaagtttgga acaaaataaa acaaaatgaa aatctgatgc
     1921 gctttattga gacgactcaa aagcgcatca ctgattcaga aatgagtacg acctctgtcg
     1981 tcgttgctta ttatttactc ttgtctttat ttccattgat tattgctttt ggtaatattt
     2041 taccgtttct ccacatcgat caagagactg tactgaccta tttacgagaa gtgattcctg
     2101 agaccgttta ccagtttatc ggtcctgcaa tcaaagacct tttgacacaa agttcaggag
     2161 gcttgttatc cgtttctgca ttagcggctt tatggtctgc aagtcaaagt atcaatgctt
     2221 tgcaaattgc gatgaataaa gcgtatggcg tagaaaatag aaaaaatttt ttgatcgtcc
     2281 gtttcttctc actaattgtc attgtcttgt tcatgattgc tattagtggg gtaactatcg
     2341 ttcttgggtt gggacagctg attttggatg ctattcagcc aatcgtacaa atacccgtga
     2401 actttatcga tcagttccaa actttgaagt ggccaatcac attggtagct ttatttgtca
     2461 tcatgttctt gatttattta attgtcccta atgctcagtt gaagttgaag acgatcattc
     2521 cgggcacgat cttcgctact gtcggctgga tgctgttatc acaagtgttt agtatctatg
     2581 ctaggtattt tgcaacgagg atcagcggtt atcagatcat aggaagtttt attgtactca
     2641 tgctttggct taattttgct gctacgatca tcattttggg cggaatcatc aatgcagttg
     2701 ttcaagaata cgtgacgggt catcaaatca aaaaacgtcg agatccaagc cgaaaatggt
     2761 tcaataaatt gaaaactaaa ttttctcata aaaaaaagta gaaacaagag ttcttattgt
     2821 aaatttatat cagtaattta taataattat gactcttaat taaagtaggt gcccatatgc
     2881 ttgtttcttt tagtatggtt ataagatttt ttctgacaat tttattatca ctgatattaa
     2941 cacctgtatt caaaatcatt tcagtacaaa caggtatggt cgacaaacca aatgaaagaa
     3001 gaataaataa agttccaatg ccttcagcgg gcggactgcc tatctttatt tcatttgtta
     3061 tatcgacttt attcttattc cgtaaaatta tccctcaatc gtatattgta ccgatcttga
     3121 ttgcttcttt agtaatcata gtcacaggag tgctcgatga taaatatgag ctgacaccta
     3181 aacaaaaaag tatagggatc ttgattgctt ctcttattat ttattttgta gcagatatac
     3241 gtattgattc cttcacgctt ccttttattg gatatatcca actaggctgg cttagttttc
     3301 ccgtaacgat tttttggatc ttcggtatca cgaatgcggt caatctgatt gacggtttgg
     3361 atgggctggc ggcagggatt tcattgatcg gtttaattac gataggaatc attggatatt
     3421 ttttcctcca tgcttctaca gtgtatattc cagttgttat tttctgtctt gtagcaagta
     3481 ttatcggttt ttttccttac aatttttatc cggcaaagat ttatttaggc gatacaggag
     3541 ctctattcct agggtttatg atggccgtcc tttcactaca agggctgaag aacgtgactt
     3601 ttgtttcatc gatttctttg ctgatcgtca tgggagtgcc ggtaacagac acgttttttg
     3661 ctatcattag gagaaaagca aaccgtgttt ctttttctac agcagataaa aaacatcttc
     3721 atcaccgact aatcagttta ggctttactc ataaaggtgc tgtcctgacg atttatgcga
     3781 tggctttgat gttttctttc acagctatgg tcatgaatta tactggaaga atcggaacga
     3841 tcatattgat tattgccatg ttgtttgctg caattttatt atttgaattg attggtctga
     3901 tcaatgagaa acatcagttt attttaaaaa cattgcgatt tttagggaat aaagagtacc
     3961 gtacgcaagt aaaacagaaa tatttgaaga aatggaaccg tcatatagat gaataacaaa
     4021 ttaaaccagc cgatccttat tagtattgtg acggcaaaca gtgataaaat ttttcggaca
     4081 ctagataatt ttatttcaac tgtaaaagat gaaacagcag taaaaatccg aatttttgac
     4141 aacaattcac ttcccgagta caaaaaaaga ctaacagagt ataggaaata tccctacatc
     4201 gatatctatt ttcatgatga aaattccgga tttggttatg gacataatca caatctgata
     4261 gctagcgatt ctcgctatgg cattatttgt aacccagata ttttagtgga tgaagagaca
     4321 gttacagcat tggtcttgtt attgaaagaa catccggaat gtgcgatgtt agcacctaag
     4381 attcttaatg aagatggaac aactcagcac ctcatccgtg agcagctggc tgtttttgat
     4441 tacgttttgc gctttgtgcc tttcaaatgg gtcaaaaaaa agtttgacaa acgactggct
     4501 gtgtttgaat gccgaggatt gcctactgat gctaatagtt atgtacggat gatctcaggt
     4561 agttttatgg tagctgatat tgataaattt aaagagataa aggggtttga tgagcgtttc
     4621 ttcatgtact ttgaagacaa cgacttgtgt ttgagttttg aaaaagcagg ttacaagtta
     4681 ttgtacacac ccttttatgc agttatccat ttttacggga agggtgcgca tcgaaatgca
     4741 aaactgtttc gcgtgttttt gacttctatg atgaaatttt tcaataagtg ggggtggcgt
     4801 tttttctgat gaaaccagaa atattagtag tcgttgtgct ttatcagcaa ctattcagtc
     4861 aatctccagc ttatggacca ttaagcaaag cacttagcga aaagcaaatt cagcttatta
     4921 tttacgataa tagtcctcaa aggcagcaaa atgagctgtt tgaaaaagaa aatatcgttt
     4981 atcatcatga tccgcaaaat cctggtttag cggtggctta taattttgcg ttgtctcaag
     5041 cagatgaagg aacacgttgt ctcgtcactc tggatcagga tacgaggcta gtcgacgatt
     5101 attttgaact attgcgtaaa gtaaccttta cagatgaatg tgttgctgca gttccgatga
     5161 ttttttctgg gagccgacaa gtttctcccc tatattcaga tcgttatatc aatcgtacag
     5221 ctcaagcagt agaagttgaa ggcccaacag ctgaacgaat catggcaatc aattcaggtg
     5281 ttgcctggtc tgtcaaattt ctaaaaaaga ttggcgggtt taatcctgct ttttctttag
     5341 attttttgga tcattggctg ttttggaaag tggatcagtt ggaaaaaact gtggagatcc
     5401 ttcctgtacg aatggaacat gatctttcgg ttttagacta tgaaaaagtt tcaagtaatc
     5461 gataccgttc tattttacaa gcagaaaatc gattttatca tgaatatgat caaaggcatt
     5521 tatccagtca ccgacgacaa ttattgttaa gaacagctaa acagttcttg accgtcaaaa
     5581 accggcatat ctggcggatg actttgcgct catatgttaa gaattggaag gtgtgaattc
     5641 gtgcgttcgg tttgtatagc tacctttaat ggaggcagat atttaagaga gcagttagat
     5701 agtattttat ctcagctttc agcagaagat gaagtagtca tttctgatga tgggtcagta
     5761 gatgatacat gggatatatt aactgaatac gcagaaaaag ataagcgaat ccagcttttt
     5821 tcggggcctc gtcaaggatt gatcgctaat tttggttatg cgatccagca gacgaaagga
     5881 gatctaatct ttttggcaga ccaagatgat gtttggttgg agacaaaagt gaaaaagatc
     5941 actgactatt ttgagcagaa tccggatcag ctagtagtag tttctgattt aatcattgtg
     6001 gacagcgagc tgcaagagat ccatgattcg tatttttcgt ttcgaaattc caaagaagga
     6061 tggcttaata atgtgataag aagtcactat attggtgctg gtatggcttt ccggtcttct
     6121 ttaaaacccg atattttgcc gatcccgtca gaagtgccga tgcatgatat gtggattggt
     6181 ttgctgggag gaaagaagac tgggttccta agagaaccgt taactctgta ccgaagacat
     6241 gatttaaacg cgagtgagat tgaaacacat tctaaattac ggcaaaaaat ttcttggcgt
     6301 gttcatctga ttacggcgtt gatcaaacga aaatggttta aacgttgata aaagatgttt
     6361 aaatccttaa tatttccatg acaaatataa caattgatga gataataaca aagtgaaatt
     6421 tgaaatcaaa aaggagagca gatatccatg aagggaatca ttcttgctgg gggcagcgga
     6481 acacgtctgt accctttaac aaaggcaaca tcgaaacaat tgatgccgat ttatgacaaa
     6541 ccaatgattt attatccaat gtctactctg atgttggcgg gaatcaaaga aattctgatt
     6601 atttcaacgc cacaagatac accacgtttc aaggaattat ttggaaacgg aaatgattta
     6661 ggactgcaga tcgaatatgc agtacaagaa agtccagatg gattggcaca agcgtttatc
     6721 attggagaag aatttattgg agatgatagt gtctgcttgg tattagggga caatatttac
     6781 tatggtggcg gtctgtctaa aatgttgcaa cgagcagctt caaaagatac aggcgcgaca
     6841 gtatttggct atcatgtcaa tgatccagaa cgctttggtg tagtagaatt tgatgagaat
     6901 atgcaagctt tgtcgattga agaaaagcct gctcagccaa aatcaaatta cgctgtaact
     6961 ggcctttatt tttatgacaa tgaggtaatt tctatcgcta aaggtatcaa accttcagaa
     7021 cgtggagaac tagagattac ggatgtcaat aaagcatatt tggataaagg aaaactatcc
     7081 gtagaactta tgggacgcgg atttgcttgg cttgatacag gaacacatga atcattgctt
     7141 gaagcatcta cctttatcga aacaattgaa aaacgtcaga acttaaaagt ggcttgtttg
     7201 gaagaaattg cttaccgtat gggctacatc gataaggaac aattgctggc ccttgcacag
     7261 ccattgaaaa aaaatcaata cggtcaatat ttattgaatt tggccgctga ataaggagtc
     7321 cttacagatg aaagtaacag atacaaaatt aacagatgtc aaaatcgtag aaatggacgt
     7381 ctttggcgat catcgcggtt tcttcacaga aagttattca aaagcaaaat ttgcagaaca
     7441 tggattgaaa tatgactttg ttcaagacaa ccattcacta tcagctgaag ctggtgtcct
     7501 tcgggggctt catttccaaa aaggagaagc tgcacagaca aaattgattc gggtagtcac
     7561 tggagcagtt ttagatgtag tagtggatat ccgcaaaggt agcccgactt atggtcaatg
     7621 ggacggattt atcttatctg aacataatca tcgacagttg cttgtaccta aaggatatgc
     7681 ccatggattc gttactttga caccaaatgt gaacttcctt tataagtgtg ataattacta
     7741 taatgcagaa gcagatgggg gcatcgcatt tgatgatcca gatttagcga ttgattggcc
     7801 aattgatcca tcaagagcga ttatgtcgga aaaagatcac cgtcatccga cattaaaaga
     7861 atttgaagca gaaaatccat ttgtttacgg agaaatctaa gaattaagga gaaattttct
     7921 tatgaaaaac atcattgtta ccggaggtgc cggattcatc ggctctaatt tcgttcatta
     7981 cgtggtaaac aatcatccag aagtgcatgt cactgttttg gataaactga cttatgcagg
     8041 aaacaaagag aacttggctg gacttcctag cgatcgcgta gaattggtcg taggagatgt
     8101 tgcagatgca gaattagtgg accgtctagt aaaagaagcg gacgcagttg ttcattacgc
     8161 ggcagaatcc cataacgata attcattaaa agatcctttc ccatttgtac aaacgaatat
     8221 cattggtacg tatacacttt tagaagcttg ccgcaagtat gatgtacgct atcatcacgt
     8281 atctactgac gaggtttacg gcgatcttcc attacgtgaa gacctgccag gacatgggga
     8341 aggcgaagga gaaaaattca ctgcggaaac accatataat ccttcaagtc catattcttc
     8401 tacaaaagct ggttcagatc tgttagtaaa agcatgggtg cgttcttttg gcttacgtgc
     8461 aaccatttca aactgttcaa acaactatgg tccttatcag catattgaaa aatttattcc
     8521 tcgccaagta acgaatatct taagcggtat tcgtccaaaa ttatatggcg aaggaaagaa
     8581 tgttcgtgac tggatccata cgaatgatca ttcttcagca gtgtggctga ttttgacgaa
     8641 aggcagaatt ggcgaaacct atctgatcgg tgcagacggt gaagaagata ataagaccgt
     8701 gatggaattg atcttagaaa tgatgggtca accaaaagat gcgtacgacc atgtaaacga
     8761 ccgtgcagga cacgacttgc gttatgcaat cgattcgaca aaattacggg aagagttagg
     8821 atggaagcct gagtttacga acttccgtga tgggttggct gacacgatca aatggtacga
     8881 agaacatgaa gactggtgga aaaaagaaaa agaggccgtt gaagcagcat atgccaaaaa
     8941 tggacaataa tacagagaaa atgtcactgt attaatggaa aaacacatgt gaggcaggcg
     9001 ctcgcctgtc tcttttttaa aataaaaatc aaggagcgga taatcatatg tttttattaa
     9061 ctggaggaaa tgggcaacta ggtacagaat tgcgccattt attagatgaa aaaaatctgc
     9121 aatatgtttc aacagatgca aaagacttgg atatcacaga tgccgagaaa acaatggctt
     9181 acatcacaga attaaaacct gatgttattt tccattgtgc agcttacaca gcagtagata
     9241 aagcagaaga agaagcaaaa gaattagatg agaagatcaa tgttgatggt acaagaaatg
     9301 tagcacttgc agcaaaagct gtgaatgctc aattcgtcta tatcagtaca gactatgttt
     9361 tcgatggaaa aaacaaaaat gtagaatacg aagtagacga ccaaacgaat ccactaaatg
     9421 aatatggtcg tacgaaatta ttaggcgaaa aagcagtaga agagatttta gaagactatt
     9481 atatcatacg aacttcttgg gttttcggga tctatggaca caatttcgtc ttcacgatgc
     9541 aacgcctagc ggaaacccgc gacaaactga ctgtagtaaa tgaccagttt gggcgaccaa
     9601 cttggacacg tactttggca gaatttatgg tatatgtcat cgaagaaaaa gcaccatttg
     9661 gtatttatca tttgtcgaac gaaaatagct gttcttggta tgaattcgca aaagaaatat
     9721 tgaaagatac agatgtagaa gttgcacctg ttacgtcaga agaatttccg caaaaagcaa
     9781 cacgtccgca gtattcagtc atgagcctga aaaagacaga agagttagga tttgtcatac
     9841 caacttggca agaagcactt gcgcaaatgc tggaagctgc caaaaaaatg aataagtaat
     9901 ttccttttat caaatagaat ttggagcatg atatggaaaa acaaacaaga agtgcacgac
     9961 gaaaagaaaa gccaaaagcg aaccaggcag attcgaattt ggtgcttgac ctgtttctaa
    10021 aactccgcta tcttattggc gttttagtca tcgtggtcat cgttactttt aatttaaacg
    10081 gaagttcact tggtgtttgg gataaatatg tgtcgcaaag agacgatggg aaaaaaactg
    10141 atgtgatttt tggacagaat cgggaagtgc ggtcagacga atggctggtg cagacacctt
    10201 tttacctctc acaagctgaa gaggactttc cgttggtgaa cgaggattat tcattaaacg
    10261 gacaaaacat gatcattgcg tataattctc ctgcaaagga tattacggtt atcggaaaac
    10321 cattcaactg gggattcttt ttcctcggaa gagatcgagg actttccttt tattgggcga
    10381 tgaaattagt cgtcatggtc ttgcttggat tcgaagtact gatgatatta acgaagagaa
    10441 aaaaagctct atcgctaatc ggtgcatttg cgctgacatt ttctccagca gtccagtggt
    10501 ggttcatgca acatgtgggc gatttgattt tctttacttt gggactgatg actgcttttt
    10561 atcattattt ctacaatcat gataaaaaat ggctacgaac gttgatgatg cttttggtgg
    10621 ttattttcgg tattgggttt attttagtga tttacccagc ccatcaagtg atgctggcgt
    10681 acttgctgat tttttatttt gttggcctgc ttatttacta tagcaagaaa gtttcatggg
    10741 atctgttgga tgtagtgttg attggagggg cagttttatt tattggcgga gtcatggttc
    10801 atttctggct aacgtcaaaa gacgcattgt tagcttcttt gaatacctta tatccaggaa
    10861 aacgggtaag tactggagga aagtggacga ttggcgaatt tttttctttc cttacaaatt
    10921 ggaaaattcc ttttgaagat atcaactatt cgaataactc tgaagtggcc ctgttctatc
    10981 acttttttcc aactgtattc ctagcaagtc catttgtgtt atttggcaaa aaagatagcg
    11041 aacaaaagtt actgggacgt attttgatga ttttttgtct gttttctatc ttttggatta
    11101 ccgttgggtt gccaaaatgg ctagcagaaa tcactctgct gtcttatgtt cctccattaa
    11161 gagccatcct tacttttagt tttgcggctt gtttattatc gatctggttt atcgcttata
    11221 tttggagaga agatgttatt cctatttggt ataaattcat tttgttggca gtaaatgcat
    11281 ggtcttattt ctatgcgatt acgcattcga aaatagataa ttatttttcg gattttgaaa
    11341 ccatcgcagt tgctgtgttg ggaacagtga ttttagcatt tgcattattt ggctggagac
    11401 gcttgtttta cctcgctttt gccgccttag ttatcgtatc tggctttttc gtcaatccag
    11461 tcgtagaagg tacaggagcg atttttgaaa aaacactggc aaaagaaatc caaaaaatcg
    11521 atcaacaaga tcctggtaaa gtttggttgt ctgaagatga attatataac ttcaccccaa
    11581 cattgggagt gaaatccttc aatacagtac gcttttatcc agatatagct gcatggaagg
    11641 aaatcgatcc gaaagaagaa tacgagaagt attataatcg gtatgctcat acaagagctt
    11701 ttatcgctaa ggaagataca aagttcattt tagatcgtcc agatatgttt tcggtcacgt
    11761 tgaattttga agacgcagaa aaattaggga tcgactatgt gatcagtaaa cgaccattaa
    11821 ctgattacaa ccaattatat gaagcgcagt tcacgcagct atatggaccg gataaagacg
    11881 gttatatgat ttttaaagta gaatatccgg attatccaga tgtaccacaa acacaaactc
    11941 aggaaaatca gctagtcgta cagtaatagg ctagctgaga ataatcctga aatattagta
    12001 gaaaggagag tggagataat tcaagcaatc gtacaaaaat ttgtcaacaa aatgagtgtc
    12061 ggtttcttgc ttttgttgct gacgctagtc ttttttgttt gtacagcagg gttaggtttt
    12121 ccagcaactt tgtttatata taacaatagt tcattactta tcgcttttag tgtggctatt
    12181 ttgctcattt taaatgttta taaagcaaaa ggcgtcgatt ttctttatct aggtgttgcg
    12241 cttgcccttt tcattttctt ttcttacttt cgggaattaa gaaatgagtc tttatttgga
    12301 gatttactgt ttcctttgat tattttattt tgtttagtaa ttaaatggat cgagtggaca
    12361 aaatgggatc gcggtattta tctgattgtc tttacggtct tcctcggaat cacgttatat
    12421 cgtgtattta cagagatcca agtaccagaa ggacaaagca tctgggctcc aggcaattcg
    12481 ctttctgata tttggatcaa tacgaataca atcggaagtt ctttgatgac tcttgcttta
    12541 ttgatcagtg gatttgccag ttcttttgaa cgatggtatg tacgaatcat cggtgcagta
    12601 gcagttgttg cagcttttct cgggatttgg gtctgccaat ctagaggtgc attagtcgcg
    12661 ttgattgttt ttgcgatatt ggatctttta cctaaatcgt tgatgcgtgt cattcgtgcg
    12721 ccatttattg cttacacggt tacgattctt ttagctttgc cgatttctta tctggcggct
    12781 gtctctgaaa aagtcaattt gtttaccggt cgagaagata tttggcataa attctatcag
    12841 acgctaggag aaaaatctga acaagtttta ctaggaatga aaacatttat cttccaacga
    12901 ggaaaccaat ttttaggaaa ccacaatagt tataattcta ttttgaatat ctatggattg
    12961 ataggatttg ggattgctac tttgctgctt atccttttta ttggtcgctt aacgttgaaa
    13021 gcagatttat ccaacgggca gatgactttt atctgggcct tttttgcggt gatgatgcag
    13081 tcatttatgg aggatacatt gacttcatac ccatgggttc cgattattta tatcctgttg
    13141 gctatggccg ttcatcgata tgatgaacca gaagttgcgg aggaattcta tgttatggaa
    13201 gaggcatatg acgatatgac ttatgatgat acatcttatg aggaacaacc agatagcgct
    13261 cattcttcca ggatccaacg ctatcattga taggcacaaa atacggctct ttgtcaataa
    13321 ggactgatgg gttgtacaaa atcaaatctg ggtcagaatg aacctcattc tggctcagat
    13381 tttttgttat cttactttga ttaattgatt gatcaaaaag attctaat
//
LOCUS       DAXLPQ010000062        12983 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.063, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000062 DAXLPQ010000000
VERSION     DAXLPQ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.063"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..3044)
                     /locus_tag="ACF3UO_002287"
     CDS             complement(<1..3044)
                     /locus_tag="ACF3UO_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFD3658243.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPE
                     DKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVT
                     FTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEF
                     VSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVS
                     AAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
     gene            complement(3661..4095)
                     /locus_tag="ACF3UO_002288"
     CDS             complement(3661..4095)
                     /locus_tag="ACF3UO_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658244.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(4112..5317)
                     /locus_tag="ACF3UO_002289"
     CDS             complement(4112..5317)
                     /locus_tag="ACF3UO_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFD3658245.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            6011..6397
                     /locus_tag="ACF3UO_002290"
     CDS             6011..6397
                     /locus_tag="ACF3UO_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFD3658246.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            6491..6682
                     /locus_tag="ACF3UO_002291"
     CDS             6491..6682
                     /locus_tag="ACF3UO_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658247.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            7196..7528
                     /locus_tag="ACF3UO_002292"
     CDS             7196..7528
                     /locus_tag="ACF3UO_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658248.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7438..7632
                     /locus_tag="ACF3UO_002293"
     CDS             7438..7632
                     /locus_tag="ACF3UO_002293"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3658249.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            7671..7817
                     /locus_tag="ACF3UO_002294"
     CDS             7671..7817
                     /locus_tag="ACF3UO_002294"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658250.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            8255..9595
                     /locus_tag="ACF3UO_002295"
                     /pseudo
     CDS             8255..9595
                     /locus_tag="ACF3UO_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9836..11452)
                     /locus_tag="ACF3UO_002296"
     CDS             complement(9836..11452)
                     /locus_tag="ACF3UO_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD3658251.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            11570..11788
                     /locus_tag="ACF3UO_002297"
     CDS             11570..11788
                     /locus_tag="ACF3UO_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658252.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11983..12444
                     /locus_tag="ACF3UO_002298"
     CDS             11983..12444
                     /locus_tag="ACF3UO_002298"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658253.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(12637..12876)
                     /locus_tag="ACF3UO_002299"
     CDS             complement(12637..12876)
                     /locus_tag="ACF3UO_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658254.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12900..>12983)
                     /locus_tag="ACF3UO_002300"
     CDS             complement(12900..>12983)
                     /locus_tag="ACF3UO_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFD3658255.1"
                     /translation="YNELHNWPTFYPASLSKHEIAQEMMAH"
BASE COUNT         4188 a         2445 c         1988 g         4362 t
ORIGIN      
        1 ccttctactg ttggctcata tttatcggcg tcagaacgat tgtctgtcac tgtaacatct
       61 acttcaactt catcagatga tccatctgga tatgtcacta caacagtccc ttttttattt
      121 ccagctgcgc taacatctac tttttctttc caagtatact tagtatcttt tggtaaatct
      181 tctttgttct taattccctc aaatgcgtct ggttccttat tcaattctgt agtcactttt
      241 tgaccttcag gattatattt gtcagcgtca gatttatcat ccagttttgt tgcacttgat
      301 acaaattctg tatcatctgc tgtaattggt tgagttgctt cctctggcca tttcgcatct
      361 gtataaccat cttttgcttt caacactgga agtttatctt ctggtaagct tacgccgtct
      421 ttcactgcaa agactgttgt tccactttca atacttgttc cttctcctgc ggtgaaggtt
      481 actttgtggt agcctgcagg aatgttttct cctggatttt caatgatatc atccagtttt
      541 gttgcacttg atacaaattc tgtatcatct gctgtaattg gttgagttgc ttcttctggc
      601 catttcgcat ctgtataacc atcttttgct ttcaacactg gaagtttatc ttctggcaag
      661 cttacgccgt ctttcactgc aaagactgtt gttccacttt caatacttgt tccttcccct
      721 gcggtgaagg ttactttgtg gtagcctgca ggaatgtttt ctcctggatt ttcataaata
      781 tctttactta cagttactgc taaatcggtc gtgcctacag aaccatcttg gtaaacaatt
      841 ttaataggaa ttgttccagt aatcggctcc gattctccta cacctttagc tggagtgaat
      901 gtaacaatac cagtgtttgc atcaacactt gcattaccga agtacttatt atagacatct
      961 gaaattgaaa aggcatcttt agctaaagga acatctggtt tatcaaatgt aggttttcca
     1021 ctttgaactg tcgtttctgg agttgttgtt ataggtacgt atgttgcatc attttccata
     1081 gcttgagaag cttttacagc aaactctaca tccacgtcga aagttcgatt tccgatctta
     1141 acagttacaa tacctttcgt actatcagta acgttagaag tatcaggctc tgttttccat
     1201 gaatactctg catcttcagg taagttttta ttattccgaa ttgattcttt agcatctggt
     1261 ttaaatccaa ctaccacggt ttgtttatca accgcttttg gtgattcctt aataacggtt
     1321 gaaccttctt ctggtttatc aaaacctgga gaaacgattt ggatttttaa ttcatctttc
     1381 gcgattaatt tacttgaatc tacacccgta aattcaaatt ctacagtatc tgaaattgga
     1441 gccccatctt tttcatttgg agcgatagtt ttttctgcta atacagtacc ttctttatca
     1501 acaagttggg ctttgtgacc tgttcccgct aactcgtgga tgaatacttt ccccttaact
     1561 gttgtgtcaa catcatatac ttcttctaat tcaggtttcc cgatatatgg attcgtgtct
     1621 ccgctctctt ctttatcgtc agggtttcca tcaccatcaa tatcttgcaa ataataataa
     1681 cctgttccat aagtgttctg gattaatttt ttattcgtat ccgacaacca agaatcaaag
     1741 atgaaatctt caccaaatgg tttattttct tcaacttgtg ctgttgcttt catatcttct
     1801 aagatttcat ctaatggctt agtcaattgt aaaacatatc gaataacgac tggacgtgga
     1861 cttgcattag caaaatcgat aagtttagtt aaatcattat tagttattga acctatgcca
     1921 taattttcat gaccttcccg tcgctcgatt gctaaatcag ctacttttgt tccggattca
     1981 aacgaaacat catatgttac tttgtcagcc tgaaccatgt gcatctgtat acccgctaca
     2041 tatggaacta atcgttcatc aattttgtaa ttagcatacc aaggcgtgcc ctttgcggaa
     2101 gatgaatatg agaaattata atttttcgtt aacttatgat ctaagattat agctccatta
     2161 gcacctgtgg atcctgaacc atcttttgtt tgagtattag gtttctcata ttttgcactt
     2221 actgatccat gtttaaactg gtcaggatta ttttcagata catctaagct attatagaaa
     2281 tcatctgaat ctgttaaaaa gtagcccgta ctatcaatac ccggtacaat tttatcatcg
     2341 tcttgatgac ttaccaagta gattcgatac attaaacgat cggtcttgag attgtctatg
     2401 cctatctctt taaaaatttc atctaggctc ttttcaaacg taattacccc attaggagcg
     2461 gtttgcgtat cggttgtttc tgccccagca aataatccat cacttgcacg aatataattg
     2521 accttccaaa tatttgtagg tctacccagc gaatcattaa ttcttacaaa ggtccgtcta
     2581 gaagatccaa ttcctttctt tggatcgacc tgaatttttt ctacatattt agctaatcgt
     2641 tcatctaatt gaagacggat ttcccagttt ttagttgatg ctgcaatatt atgttttccg
     2701 taaacttcaa atccaattgt attgcctttt agtgtgtctc cagttagttc ttgaggacta
     2761 aattgtaaat ccgaaaagtt ataatttttc gtataaccag gattctcctg aaaagtattc
     2821 cccgaagcta ctttgtcacc tacttgtacg gagcttatcg ctgtttcaag tgggctgctt
     2881 ggagaaattt catcttgtgc tttaactagt tcagttgttc ccaagacaag accaacacca
     2941 atcaaaacag atgcaacccc aacacttaat tttttgatac tgtacttcaa tactcgtttc
     3001 tttgtttttt ctagaaatac tctcttatta ttcttgctaa ccattattca aatcaactcc
     3061 cttaataatt actttcctag taagaataaa agataaatct gatacgtatt attcacagaa
     3121 taggaatctt actaacctta tgttaactaa tttacttaga gaatttcatg aacattacaa
     3181 caaaaaaagt acatttcttc atgttttttt cggatatttg tgctttttaa ccattcagca
     3241 gctgaaaaca tataaaaaga tatgtatgta ttctttctga aattaagttc atttctatgc
     3301 gatgaagcat gttttcaaaa tattaccctt tcttagatta aacttcagag tattcaaata
     3361 acggaataag gagccttatc ccgcattact gaatgagact gtgacataag taaaaaggtg
     3421 acttcaaatt ccttcttcgg aatttgaaat caccttcttt ataattataa agtatcggtt
     3481 tcacagcatt tctgaatgat tcctagaatc ttaaacgaat gattggagtt atcaacattt
     3541 tttcactcgt ttttagcgaa acaaaaaatg acatttgtca cagcctcatt aaattattga
     3601 ttctttttct ttataattga attgtccata tttaaagtgt ctagtactct acatgaataa
     3661 ttaattgctt tcactcaaat acttataatc tattaacttg tagttgttta acttttctga
     3721 aaaagttaga cccacgtaat aatcttccca gctttctctt tcaattaact gatccaattt
     3781 ttgataatcc ataaattcat catgtatcaa aaagaataaa taacttgata ttttagcatc
     3841 tagcttaatc agattaaata atgtttgttt aaaattgcta ccattaatat gactgataga
     3901 ttctctagct tcttcacata aactttttac tttattaatt actactttgt catattcatt
     3961 taacacacta ttattaccat tacttagacg ctcagattct acgaaacaac tcaaatcaga
     4021 aatttcccaa aaaaattttt tgttaaaatc caatttcctc aactcctcca aactacgtaa
     4081 atgatatagt ctcataataa aataaaacct ctcagctaat gttgttgaaa ttgtccacta
     4141 aacctaattg atattgctta ggagatacac ctgcgtactt tttgaatact ctcgaaaagt
     4201 gtgaagaatc tgaaaatcct aaacctaaag aaacttcact gatagtatgg tttgatttca
     4261 acattatttt agccgtagaa atttttcgct tagagatata attataaatc gtaatatgca
     4321 tttcattctt aaagctttct cttaatttag tttcacttac agaaaaataa ttagctattt
     4381 cctttacagt aattctttta tagatattta agccgatgaa ttgaacgaca gaagaaatta
     4441 agggagaaag atgctctatc ttagtttttc cgatttcctt agtataataa acaatcccag
     4501 aatccctcac ttttaagacc tcaggtaacg atacagctaa ttcgttttct tgtatcaaag
     4561 catctctact ttgatacgct tctattatat ccattcctaa tgttatagac gtttgtgcta
     4621 acttttcaaa aacaatgata gaataatttt tttcagaccg aatcgtatct ccactaacac
     4681 ttggaattat tccattactc agattaaaaa ccatgttttc taaatttcga atatctccat
     4741 ttttaacata ttccagtatt ttattttcat aaagaaacag atatatttct ggatcgtaat
     4801 tttgtgataa cagattatct attttgattt gctcgatagt tttacttaga ttttctgtat
     4861 attcaattaa cggttcatgg aatagatctt ctatttttcc agtaaaaaaa taatgaacta
     4921 aaatcagaat atctcgaatg tctcctaaag aatacaaagt caaattttgc aatgaattat
     4981 agagtcgttc tctatcagcc attgcaacat tcaaattgtt catttttagt ttaaaaaaaa
     5041 ctttatcaat attatttgct ctaaatggac caaataagta atatctggtt ttaaacatgt
     5101 atagaagaaa catctcatta aaatcaccag taaagaaatg gaaatcttta gtttttttaa
     5161 tattatcagt tagtaacttt ttataatcat aaaaaaaata agtagttcta tctgagcgat
     5221 actcttttat aatactgaat tcggaattaa aaaccacgat aggtaacttt aaacaaacat
     5281 gaagagactt taataagact tctttatctg aaaacacttt tgtttctctc tttcctttct
     5341 acatcattaa atagtatttt atacgttatc taaaatacta ttcctctgtc aaaataagct
     5401 aacttacttc attataaaat atccacttat cgctttcatg tatattccac cgtaaaaagt
     5461 acattttatc accgagaact catcattttt catcatgatg aatactattt acatatatct
     5521 agttcaaaga caataattat tatgatccgt tattatctaa gcactataca gataatagga
     5581 atttttcgtt tctaaatatt ccaatttggg aatccaataa aaattttcgt tcaaatacgt
     5641 gtctattcga actcttttct agttgttaat tatgaagggg gaagaaataa aaaatacaat
     5701 ctatacacga ataagaatat tatccaaaag gaggttttag aaaagattta ttatacgtaa
     5761 aaagctcaag acattttctt agccataagg acatgtttga tatttaagaa gatatatgaa
     5821 ttttcttttc taagtataaa gataactatc cattatcaac taaaaaaaca tttttgaaaa
     5881 taaacatcag cagtcctatc aatgcatgtg agcttataga agttattcgc agcgcagcat
     5941 aattgcatta gcttcttttc gtgttttttg cctcttttcc ctttaaatct taatggagga
     6001 ggtgtgcaat atgtcagata acgacgaacg cgtaaatgcc cagttgattc gattctttga
     6061 aaaggtcatt ttgaacaccg ctaatactta ttataaaaaa caagaagaaa ttcaaaaaca
     6121 tgaacaactt gatcaactcc caccatattt gtttactaaa gatactataa aatttaaaca
     6181 accgattaat gttttaaatg tgactctcct tgttgaagat ataaaattag caaaaatcct
     6241 tcctttgttg aaagaacctg aacaaatttt tcttatcgaa aaatttatct ttgataaaac
     6301 tgataaagaa attggaaagg ttctggggat tacaagacag ggtgcgacaa atttaaaaca
     6361 tcgactttac aaaaaaattc aaaaaatgct ggtttaatat ctgcataata actaattttg
     6421 tatgcttctt tgctcgttct cctccttccc aaagaaatag attataagtc catgggaaga
     6481 aggtagattt atgaattctt taaaagaaga tttcatttta gcaaaggctg gaaatgaaga
     6541 agctgttgag gcaattctca aaagatttag ctctttgatt cataagcaat cctggagaac
     6601 tggaaaatat gatcaagatt gttatcaaga atgtatgctt gcaatatatc tagctatctc
     6661 gaaattcgaa attaaagaat aactcaacta agggagtctg tgacataagt aaaaagatag
     6721 tttcaaattt cgaacaataa atttgaaact atcttcttta taattataaa gtatcgattt
     6781 tacagcgttc tataatgatt catagaatct aaaacgaatg attttaatta tcaacgtttt
     6841 ttaattcgtt tttagcttaa aaataacttt tgtcacagtc tcactcctaa aattacttta
     6901 tttacgtatg aagtgggcag gaggtcgaat ccagaactgg gctatggtac ttcaacgagg
     6961 acttctcctc tagaattgaa aagcatgcga tttaccttcc gtaacgacgg tagatttatt
     7021 caactatgtg tccaatcaaa atttgtctga tttcaaaaat agtcaagaga attttggttg
     7081 ttaaaaactc ttatctatca acttccacag tttagttgac aaaccctgat actaagttgg
     7141 gctatgatac acttttcttg actatcagtt acgttaccgg aaggaatgaa ctctattgag
     7201 aaaaacatat gatcgtaaat ttaaactaaa gatttcacag gatatccttg agaaaaaagt
     7261 aactaccaag aaaattgctg aagaatacaa tatctctcgt ccaacaattt cccgatgggt
     7321 ttcagaatat cgtcgatacg ggaaaaatgc ttttgctgga caaggaaaaa gattacctga
     7381 taaagcagat ttctacattc ttgaacagga aaataaacga ctaaaagagg aagacgagtg
     7441 ttctacgaac acaaagatcg atacggatct ccagggatca ctcaaaaact ttacgatgaa
     7501 ggaatcgaaa tcaataaacg tgttgtagct gttcttatgc gtgaaatgaa tttatgcaca
     7561 agaggatttc atcgacgcaa atcttctcat ggtagagaaa aaacaatcaa agaaatggta
     7621 aaaaaatgtt gaatcgataa tttgaacaga accaaattga tgctgtttgg gtgatggata
     7681 ttacttacat tccatgtaat gacggtcgcc tctatttgtc cacctatatt gacttagcaa
     7741 ctcgtattct acgttactat atggtagatt cacacatgaa aaaagagatt gtcgtccgtc
     7801 cattacaaat ttattaagga gaattgccta cggtaattca ttccgataga ggtagccagc
     7861 atcggtcttt tatttatcaa gagctgttga acgaccacca catcacacat tcagtgagcc
     7921 aaactgggac tcctgttgac aatgcagtaa ttgaagcgtt tcatcgatca atcaaatgag
     7981 aattaatcga ctccaacaaa tataaaagta aaatagagat gaaggtgtta atccaagatt
     8041 atttagaaga ctactaccca aacaaaagaa tccatacaaa atttatgatg actccttgac
     8101 aatttgaagc gaagaaaata agggatctat aatatctagt gttggtgacg ccttctgttg
     8161 ccaatacttt ttcttttttc taataaacgc aaacagacac cttaaaatcc tttagaataa
     8221 agtcgacgaa aaccattcaa aggagtgttt caagatgtcc tattcagagt ttaccaaaga
     8281 gttactagat attctagacc taaatcttat ctttcatgaa gatgcctttc gcaaagagcg
     8341 aatcaatgac gaaacatgtt ttgtttttga tggcacattg acctatcaac cggaggaatg
     8401 ctttcatcgc cactatcaaa atgaacaaac gatcattaaa tagggctgga aaaaagtatc
     8461 catcttattg aatgatgtca gtaactacaa gaccattctg cggattaaca aacagcgctt
     8521 caaatgtaaa cactgtggaa agactttttt agcagaagat tcagttagtg atcgtcgctg
     8581 ctccattgct cgcagagtca aacaagccat tcttgagcta ttaagcgaac ctctttctat
     8641 gtctttgatc gcacgtatga agcacatttc tccgaccact gtcattcgaa tacttcgcag
     8701 ccttcggcct aaaaccattt ctttgagcca gctgttacca gaagtggtgt gtttcgatga
     8761 attcaaatca gtgaaaaatg tctcgggagc catgagcttt gtcatgatgg acggcaagac
     8821 ccatcaactg attgatattg tggaaaatcg gcaactcaat cctttacgcg actatttctt
     8881 gcgctaccct ataaaagtcc gtgaacaagt gcgtctagtg gtttcagatt tctatacacc
     8941 ctatcgcaca ttggtgaaag agtgttttcc gaatgcccga atcgtcgccg atcgctttca
     9001 tattagccaa cacattggtc gggcttttac caaccaccga attcaagtaa tgaagacctt
     9061 taaaaaaggg gatcgtcggt cgaagcactt aaagaaatac tggaaactac ttcaaaagaa
     9121 tgcgtgggaa ttgaaaggtc agcatcgcta ctggcgtccg tcatttcgag atcatctgac
     9181 agaagcagag atagtcgatc ggctattatc ttatgatgat tccttaaagc gaggctacga
     9241 agtctaccag gattttcttt ccgttatcag aagacaagat gttcctgaat tcgtcgcgct
     9301 cctaaaagaa gactacaagg agttgccaga gcactaccaa ccagtgttca cgaccttcaa
     9361 gaaataccaa acagaaatca aacgagcgtt gcgcgttccc tattccaacg gccctataga
     9421 atgtttgaat aaccatatca aagtactaaa acgaattgcc tatggctata gaaactttca
     9481 aaactaccga gaacgaatct ttttatatcg aggaaaatat tttaagaaaa ctaagaatac
     9541 tacccaactg actaaagcca gaacaacaac acggctagac aagatagctg tctagccgtg
     9601 tgagtatctc gattattcta ttgaatttct tcaccaacac tcattgacga agagccaaaa
     9661 taagtaatct aaccgactgt taactaaacc attgcaggtc ccgttaaaga tacttgtgcc
     9721 tgttgtcacc gcttcttttt cttgtccaca agcgcttaac acacttaata aagcccctgc
     9781 tattattaat aataatatct ttttcttatt aaaaacctcc tcatctattt ccagattagt
     9841 aaatgtagta atctgtgctt tcttttttct caatactaat aactaactta tggggtaaac
     9901 aaatactcgt ttgaccgggt tttgagatcc atccagttct aaccgcgatt tgatcaggac
     9961 tattatcttc tttaactcga attcttccat ctttaatctc aacaatatta tattgtccct
    10021 tcgcaggatg ataattcacg agtttatgat tgatcttatc caaatcgaag cgatccattt
    10081 ccttgccatc aattcgaacg atggcatatt tgatagcatc ttcagttgtt tcattctcct
    10141 tttctataga gaatacaaat aagggaataa aagaggtaat aatcaaaatg ccaataatta
    10201 tgacatcgcc tatcttgaca ccagcttttc ttaaaaattt cattaacgat atctggctaa
    10261 acatattaga ctttttccat ggaaatggtg aaatttttcg gaaattatct gcattaagag
    10321 aatcagttaa acaaccctca agttgttcct taatacattg ttgatccatc ttcataccaa
    10381 taaaaactag tttattaatg cgttcaccaa acaacggatg ccaggcttcc ttcaattcgg
    10441 gatttttttg tataatcatt tgacactcaa ttttaggtaa actagctacc caataattta
    10501 atgattcaat acttttatag ctacccgatg tttcaaagat cgtcgaaaaa tcactatgtt
    10561 gggcaaacca aagaaaccct tttgctcttg taatattgcc aggaaaattt ttatccgtaa
    10621 gatgggcaaa tttttgtgcg tcaaggagta accgatttcg atagataaaa cttgagatac
    10681 catattcttc tgtttcagga atatgatttt gatagccaag ctctaactct ttgaaccagc
    10741 ccactgaata ggaagtctca tctatattaa aaagatttgt atttagaatt ttcgataagt
    10801 ctacttcacc tttaattgtc ctaattattt tggcattgga ctgtaactta gcaattagac
    10861 cgttaatttt gtaaatcgtc ttggttgaca ctaagtcact attatttaaa agtaatatgt
    10921 tacaacactc gaattgatca attaacaagc cacgaatatc ctgttcttct tcaactacat
    10981 taccttcagc ttttctttcc tgaatctttt cacccgtttc gaaattatcc caaaaacgtt
    11041 ttacatccac tactataata atggcaccaa tctctaatcg ttgggtcaaa tcaatgtcta
    11101 aagggttttt agctaatata attgcttgaa taattggaat tggtttgctg attcctgaag
    11161 cttcaataac aatttgattc aagtcagaaa attgcactaa ttgatctagt tcaacaatca
    11221 aatcttcgcg taatgtacaa caaatgcatc cattcggcat cgaaacaagt ttttctccag
    11281 ttcttttaaa acctttcttg tcgactaata ccccatcaac atttacttcc cctatgtcat
    11341 ttacaatgac agcaatttcc tttccgtgat caccgtacag aatatgattt agaagtatcg
    11401 tttttcctga accaagatag ccagttaaga ttgtaatagg tatttttttc atagggaacc
    11461 tctttctata ccttgaattt acactttaag tgcaacacat aaaaatgagt cataatcgat
    11521 atccaactag tataagtttg tcgagaacac tcctagaagg aaaataatta tgagccagta
    11581 tcgtcatctt actatactcg aacgagaaag aatctttctg cttcacgaag aaggattttc
    11641 tattagtata attggcaacg acattcagca tagcccgttt actattttac atgaactgag
    11701 aagaaacaag aaaaaaacta ttcaccttcc aaagcggaaa aaaattatgc ttatcgaaga
    11761 aaaaaatgcg gacgttatca cattctaaat gatccgtgag tttggtcaat tgttcgtcat
    11821 ttatttgtcg attttcagtg gtcgccagag gaaatctcga atcgtttgaa gcatgaacat
    11881 atggactttt caattagttt tatcacgatc taacgtgcaa tttgcaatga tcttttcgat
    11941 acagaacccc tctcacacgg caataaaggc ctgatccgtt cattgcacca tcgaggaaaa
    12001 acaagacata caaaaaatca tgtcgagtct cgtggaaaga tttgccttac tcattcgatc
    12061 catggccgtc caaaatccgc agatgataga agtgattttg gtcattggaa agccgatatt
    12121 gtagctggca aaactggtgg tacttgttta gtgactttga cagacagaaa atcatgcttc
    12181 cttttagcag gaaagaaggt ccccagaaag aaagccgctt atgtgagcga gaaaatgatt
    12241 gaacttttaa gcagtattcc aaatgaggcg gtcaaaacga tcactccaga tagaggaaaa
    12301 gaattctcca atcatttcgc agttacagaa gcattgaata atatgccctt ttattttcca
    12361 gatcctcatg cccttggcaa caatgaacaa attaaaatac gaatagactc attcgagaat
    12421 acttgccaaa atcgaaagag atagctacgg tagataactc aacgataaat cagatgattg
    12481 aaaaactgaa taacagacct agaaagtgtt tagattggag aacaccttat gaagtcttct
    12541 ttgataaagt gttgcgcttg atttgacaat tcaagacata ataaaaagca gatcaaatcc
    12601 aaataaggga aaaatgatct actctggtat tatcaattaa ttggccaagc tattatgccg
    12661 ttttgctaaa cgtctacttc ttccagtatt gaccttgata aaacaacaat caggatcccg
    12721 ttttaatact ctatgaactg tgtcaatact aacatgtaaa gttgcagcaa tatcagctaa
    12781 tgtactccca tttaatctca tttgctttgc aaatcgataa cgccgataag catcaatatt
    12841 cttggaatcc atagacaata atacttttct taccatgtat ttcctccaaa aattgaattt
    12901 taatgagcca tcatttcttg agcaatttca tgtttagaca atgaagctgg atagaaagta
    12961 ggccaattat gcaattcatt ata
//
LOCUS       DAXLPQ010000063        12456 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.064, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000063 DAXLPQ010000000
VERSION     DAXLPQ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.064"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..153
                     /locus_tag="ACF3UO_002301"
     CDS             <1..153
                     /locus_tag="ACF3UO_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3658256.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(207..485)
                     /locus_tag="ACF3UO_002302"
     CDS             complement(207..485)
                     /locus_tag="ACF3UO_002302"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658257.1"
                     /translation="MENKVGYVRYNFFSSTPIMKDFASFNEALAVELSHDRERIHYEK
                     HVIINDLWNTEKTDLLALPDTDYPVFKEIEVKANKYNEIKQNKITNLS"
     gene            complement(600..1217)
                     /locus_tag="ACF3UO_002303"
     CDS             complement(600..1217)
                     /locus_tag="ACF3UO_002303"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658258.1"
                     /translation="MLTMTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLL
                     PQPKARKKTGMMYTEKWGGIVSLWLSEDAKLPNKKRRTAEAMTTALKADGFPGSYRTV
                     CVFIQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPF
                     SNAGFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVT"
     gene            complement(1612..2436)
                     /locus_tag="ACF3UO_002304"
     CDS             complement(1612..2436)
                     /locus_tag="ACF3UO_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3658259.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGIPYINNL
                     GLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQHLEIS"
     gene            2779..3195
                     /locus_tag="ACF3UO_002305"
     CDS             2779..3195
                     /locus_tag="ACF3UO_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3658260.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3192..3662
                     /locus_tag="ACF3UO_002306"
     CDS             3192..3662
                     /locus_tag="ACF3UO_002306"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3658261.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3676..4449
                     /locus_tag="ACF3UO_002307"
     CDS             3676..4449
                     /locus_tag="ACF3UO_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3658262.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4463..5275
                     /locus_tag="ACF3UO_002308"
     CDS             4463..5275
                     /locus_tag="ACF3UO_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3658263.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5329..6294
                     /locus_tag="ACF3UO_002309"
     CDS             5329..6294
                     /locus_tag="ACF3UO_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3658264.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6431..9154
                     /locus_tag="ACF3UO_002310"
     CDS             6431..9154
                     /locus_tag="ACF3UO_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3658265.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9167..9799
                     /locus_tag="ACF3UO_002311"
     CDS             9167..9799
                     /locus_tag="ACF3UO_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3658266.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10007..10231
                     /locus_tag="ACF3UO_002312"
     CDS             10007..10231
                     /locus_tag="ACF3UO_002312"
                     /inference="COORDINATES: protein motif:HMM:NF015692.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HFD3658267.1"
                     /translation="MQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVI
                     PENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10333..10566
                     /gene="relB"
                     /locus_tag="ACF3UO_002313"
     CDS             10333..10566
                     /gene="relB"
                     /locus_tag="ACF3UO_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFD3658268.1"
                     /translation="MSQSTITFRIPDDEKELVLEYAKAHNSSLTELYRNAVLDKIEDE
                     IDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10556..10825
                     /locus_tag="ACF3UO_002314"
     CDS             10556..10825
                     /locus_tag="ACF3UO_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3658269.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(11004..12305)
                     /locus_tag="ACF3UO_002315"
     CDS             complement(11004..12305)
                     /locus_tag="ACF3UO_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3658270.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         4065 a         2016 c         2444 g         3931 t
ORIGIN      
        1 tccttagaaa aattaggttg tcaaaatttc aactcacgtt ctgttaaagg gctagagagt
       61 agatttgaaa gcatattact ggcttacagt gttctattaa gtcgagcaca acgacgtttt
      121 gaaggaactt tgagatattc tttaggatat taaaattaac tagcaccacg ggtaaaataa
      181 atagtttttc tatcaagtat attgaactac gataaatttg ttattttgtt ttgtttaatt
      241 tcgttgtact tattggcttt gacttcgatt tctttaaata ctgggtaatc ggtgtccggc
      301 aaagctagca aatctgtttt ttctgtgttc catagatcat tgataatgac atgtttttcg
      361 taatggattc gctctcgatc gtgtgacagc tccaccgcta atgcctcgtt gaaactggcg
      421 aaatccttca taatcggtgt agatgaaaag aagttgtacc gtacatagcc gactttgttt
      481 tccatactac ctttctcgtt tccgctacgt ggattgcaca cctgtgtctc aaaaccatag
      541 tgcatagaaa atcggaggaa accgtcagtc agcaccgctt gttcagtctt tgtttttgtc
      601 taagtaacgg ccgttgacat attatcaatc cgtattttcc gaggaacgcc acctgattgg
      661 ctgaagagtt ctttcatgcc ttccaacaaa cattcttgat tctcggcggg gagtacaacg
      721 gcgaatcctg cattactaaa agggaaagtc atcactaata ccttcacatc tttaaacgct
      781 ccatcgtgac aaacttccat cgtaccaaaa tcaagttgcg cttctgctgg cgggtgttca
      841 agacgctcaa agccttggtc ttccagtgtt tccaagtagt gtgtcgcttt ccaatcttga
      901 atgaatacac agactgttcg gtaggatcct ggaaagccat cggcttttaa agcagtagtc
      961 attgcttcag cagtcctacg ctttttattt ggcagcttag catcttctga aagccatagg
     1021 gaaacgatgc ctccccactt ttctgtatac atcataccag tctttttgcg tgctttaggt
     1081 tgcggcagca aatcatcatc tgcatatttt ttagccgtgc gccaatttac atctagctcc
     1141 tttgcaatat gattaatgga tttatcatga ttatttcgta aatttctgat agtattaata
     1201 tcggtcattg tgagcatacc tttcttacct ccagttacag tgtcgagact ataactttag
     1261 aggagtttca ggttgcccgc aatggctttt tatcttaact taatcgattt gcggagttgt
     1321 gtagtttttc gttgcacttg tatgtacttt tattctgcca taaacagctt aatgaatgtc
     1381 cacttgaaaa agtgaataaa cgaaatagat gactcgattt aataaggaag taaacccaca
     1441 cagaaatata ggtgattttc cttgaatgac caagatattg aaagttagtg aaaaaacaca
     1501 aaaaggtagc cctattcaca gaaggtctgc cttttgtgtt atcgccagca aacattagag
     1561 ggggtatttc atatagcttt tgtcctctcg acagtcctat cagtttctct tttaacttat
     1621 ctctaagtgc tgtccagttt taatagcttc tagcttgttt cctaactgtg tttttaatat
     1681 gttgaaggct tttgaacctg tgcagtggca agtaaggatt ttttctactc gtgagtcatt
     1741 caatttattt ccaattttca ttacctcttg ctcaggtaga cctaaattat ttatataagg
     1801 tatgccaatc atatggaagc caccaattag gtattttatg ggtttagtcg gaaatgtttc
     1861 aagagcaatt tccatcatat cgataatgcc atgatgacta cagccagtaa agacaatcag
     1921 accgtcttct tgctcaatta cgaccaataa ttcatctgaa aaatcatcat aaacaaattt
     1981 atcatccatc tttttgtata aattcttggt ggtcgagttt gctttgccta gggggatgat
     2041 atggaagctc ggagcaagtt ctgttttcgt ttttattgta tgtaaattct catgcatttt
     2101 aaggatttca tttttaggaa taccaacata cagaaacgtg gttaaaatct ttaaataatg
     2161 gggtaaagtt acaccttcag ctgtataaat aggggcgttt cctgatttta aatatcttaa
     2221 cccgccggtg tggtcagaat gaccgtgtga aataatcact gcctccagat cattcaaagt
     2281 ttcccccatt ttagtcgcat tatagactaa ttttttatta gcgccagcat cgaagagata
     2341 tttcttccct gagtagttaa ttaagagaga taacccatgt ccacttttaa agttcaaatt
     2401 tattcttgag ttttcaaata aaaccttgat ttccactata acatctcctt tcacatgaac
     2461 gcgtattcat atattgtagc acattaagtt ctattttttg ttgtaattac cgaaaaaaat
     2521 attaatggac gctttttacg ctttatttcg tatgtggaag aaaatttctt aggatgtggc
     2581 gggggattgg ggcaaagcta aattccaatt acagtgatca tttaattaga cacctttaaa
     2641 tacccacact ttcatcaaca ctataattta gggaaagaaa agtgttggca tgatatagaa
     2701 aaacctttaa ttaacagcgt ttcctaaaat tggcacgcat cttgcttata gaaaagcgta
     2761 aggataggag gaatgaaaat ggcaactata attcttgcca gccatgggga atttgctcaa
     2821 ggattaaagc aaacagcgac aatgattatt ggagatagtg taccaattca tgccttgtca
     2881 gcatttagag atgaagatga atctattttg gtacaaataa aaaaactttt agccacaata
     2941 gatatagaag aaacctacat tttaactgat attctaggtg gtagtgtgaa taatgatatg
     3001 ctcactatta ttaaagagta tgagggattg caattaatta ctggaatgaa cttaccttta
     3061 gttatttcta ttgcaaccta taatggaaaa attggggaaa gtgagctaga aaagcttatt
     3121 aaagagagtc aacaatcagt gattgattgt agaaaattat tagtagaaca acttactgga
     3181 ggagatgacc tatgattaag ttagtacgta ttgaccatcg tttgttgcac ggacaggtag
     3241 tattttcttg gagtaaatca ttaaatatca atcgtattat tattgccaat aaagaggcag
     3301 cgaatgatga attcaaaaaa atgtctttga atttatctaa accgactggc attaaattaa
     3361 caattttttc agttgaacag ttactagaaa aaatgcctaa aatcgaaaca cttaacgaaa
     3421 atatcatgct tatttttggt aatacaaaag aaattcgtca attttgtgaa gcctatccta
     3481 aagtacaaga aatcaactat ggagggataa tcaaaaaaga aggttccaag caatttagta
     3541 atgccatttt cttgaatgaa tctgagcaag aagatgccaa aaaattaaaa gctcttggca
     3601 ttaaacaatt tattcaacag gtaccaactt ctaaaaaaga agatttgaat acaatgttat
     3661 aaaggaggaa tgaaaatgct cgttcagtca attggtttag ggttaatcgg tgttttttgt
     3721 attttagact caaggctttt aggaagaatg aattttgaac gaccgttgat tgtcagtacg
     3781 cttgttggtt tggtacttgg agacatggaa aaaggattaa ttgttggagc ctctttggaa
     3841 ttgatgtcct taggattagt aaatatcgga gctgcttcac cacctgatat gaatatggca
     3901 tcaattattg ctacagcctt tgccatttta tcaaatgcga atgcagaagc agcattaacg
     3961 attgccattc caatttcagt gttaggtcaa atactaggta tcttaatgcg gacgattttg
     4021 tcaaatttga ctcacgttgc ggatcgcttt atcgaacaag gaaaatttag ccaagcaagg
     4081 agaattcata tactttatgg ctcgggatta tatgctctca tgtattttat tcctattttt
     4141 ctagcaattt attttggaac gaatcttgtt tctcagattg ttgatgcgat tcctgagtgg
     4201 ctaacaaatg gcttaacggt tgcaagtaaa attttaccag catatgggtt tgcgttgtta
     4261 ttacaaacga tgttaacgaa aaaaatggtg ccatttttat tacttggatt tttaattact
     4321 gcttattctg gattgggaat cattggtatt gcagccttcg catgtattgt tgcgtttgtc
     4381 atggttcaag ttcaaggtaa aaactcaaat ggtaaccaaa atgagccaga tccattagat
     4441 gacttataag gaggtagatt aagtgaaaga gaaagatcaa aatgcatgga aatatcggca
     4501 gttcttatgg cgttcatggg caattcaagc ctcatggaac tatgaacgac aaatgaacat
     4561 gggttttatg tacggaattg caccaattct agataacatt tacaagaatc cagaagatga
     4621 agcaatgaag aaagaagctt acgagcggca tatgatgtac tacaactgta cccctcaaac
     4681 aagtgcattt gtgttagggt taactgcttc tatggaggag caatactacg aagaccaaga
     4741 aaactttaat ccggaatcaa tcagtgcagt gaagacttct ctgatgggac cgctatctgg
     4801 tgttggtgat tctttctttc aaggaacgat tcgggtatta gcctttggac taggaattaa
     4861 tttagcccaa caaggtagta ttttaggtcc aattctagca atgttaattt cctttgtacc
     4921 ttccttttta gttacttact atggtgggaa aattggctat aacatgggga ataaatactt
     4981 gtctaaactg tatcaagaag gtttgatgga taaagtaatg tatgtttgct ccattgtggg
     5041 gttgatggtc attggttcga tgattgccag catgatcggg attacaacac caattcaaat
     5101 gggtaaagct tttgtcttac aagatgtatt agatagtatt atgccacaat ttttaccatt
     5161 aggattaacc ttcttcatgt actggttatt gcagaaaaag gtcaaaacag gatggatgtt
     5221 ggcaatctgt ttagtcggag gaattatttt tagtttgtta ggtatcttac aataagggaa
     5281 taaccaataa atttggttga ataatataaa taaggaggaa ttcaattgat gaattcaaaa
     5341 gaaattgtta aagaaatcgt agcgaaaaaa gaggtaaaat caatcgtatt tgttggctgt
     5401 ggcgcttcaa aagcggacct ttatcctgca aagtattttc tagaccaaaa tgcgaagcag
     5461 ttacggatta gtcattacac agccagcgaa tttaactatg caacaccagc atctgtagat
     5521 gagtcaactg tcgttatttc agcttcttta ggaggtacga ctccagaaac agttgaagct
     5581 aacgcagtag ctaaagaaaa aggtgctaca gttattagtc taacacgaag cattgactca
     5641 ccgttaacaa aagatgcaga ttatgtaatt tatcatcgat ttgcagagaa ctatgctgct
     5701 aaattagaaa aaacaggcta ctgtttagaa ttggcagtag aacttttaca tcaagtagaa
     5761 ggttatgacc attatgaagc aatgcaagaa ggatttgcta ctatctatga tcttgcccaa
     5821 aaaagtgcag aatcagctcg taaagatgcg aagaaatttg ctgaacgctt taaagatgaa
     5881 aaagttattt atgtaatgag tagtggtgct acacatgaag tagcatactc aacatcaatt
     5941 tgcttgatga tggaaatgca atggattaat tctggtacct tccattcagg agaatttttc
     6001 cacggaccat tcgaaattgt ggataaagac gtaccgttta tattattaat gaatgatgga
     6061 aaaactagaa atatagatgc tcgagcatta actttccttg aacgctttga tacgaaaaca
     6121 gaagttgtag atgccttgga ttatggcttg tcttcacata ttgctaaaga agtcttagac
     6181 tactttaacc cattcgtgat tactgcagta tttagagttt atgcagaaga attgtcagaa
     6241 gcaagagaac atccattaac taagagacgt tatatgtgga aactaactta ttaaaaaata
     6301 gatcaaacta aataaggtgg cttgagaaat taagccacct tgttttcttc aatgtgattt
     6361 tatacatatg gtaaaataac tagtacatat ggtaaaataa ctagtacata ttgtgaaagc
     6421 aggtggcaag atgcagcgat taaatgacta tctttatcaa ctaacattgc ttttgaaatc
     6481 tacgccttca gataattatt cagctcgcag tatttcgcaa gctctacagt tgaatagaag
     6541 tacaatcagt agctacttaa atgaaggtgt tcgtgaaggg cttttcataa aagtaaaaag
     6601 ttacccggtt ttatttttac atagaacagc tcttgaagaa ctacatatca cactgaataa
     6661 ctccgaaata gaatcaattg aaagcttgtt aacaatttct caaaaacccg cattagatca
     6721 agtaattggc tctaaaggaa gtttgaaaga agcaattgat caaattaaaa cggcagtctt
     6781 atatcctgga aaagggttgc ctttattatt gatcggcgct agtggatcag ggaaaacctt
     6841 tctagcgaat aaaatatatg aatatgcagt agaagaaaag gtcattcaca catcggcacc
     6901 tttcatagat tataattgtg cacaatatgt gagcaatcca gagttactat cctctgcttt
     6961 atttggctac acgaaaggag catttaccgg agcaagccag gagcatactg gtttgctaga
     7021 aaaagccgat ggaggagtat tgtttttaga tgaagtgcat cgcttatctg aagaagggca
     7081 agagaaatta tttacattta tggatacggg tgaattctct cctatggggg ataatagtat
     7141 tcggaaaaaa gccgatgttc gattagtctt tgcaacaaca gaaaatatat atacgacttt
     7201 cttaccaact tttcttagga gattgccagt tattgttaat ctacctagat ttcaacaacg
     7261 tccgtcgttt gaacgtctgt cattgattga tgaatttttt gtttctgaga gccaaatttt
     7321 agctaaggaa ctatctgttt ctgatgcatt gattcatttc ttaatgaata gtgattttga
     7381 aggtaacgtg gggaatatta aaaatattat caagtatgct tgcggaaacg catatatcca
     7441 ccagaagagt cagcaaacaa ttcaagttaa attattggat atgcctttag agtacagtta
     7501 taaattcaag gagcaactaa ataaacccag aaagaaaaga gcagatcgaa tctactatcc
     7561 agaagaaaca cgacaagtgc aactagaaag aaacaatcag ctttttgttc aattttttga
     7621 ccaattactt actggattct ctgaagtgat tgaaaataac aaggatatta aactattttt
     7681 agaagaaatg gttaccaagg taacacaagt aatggatacg cttatttttc aagaggatta
     7741 cgaaaaagag cagtctttat acgccattct aaactatcat attcgtcaaa gtattgattt
     7801 tatgcgagaa agctacgggt ttgaacaaga tggtaaccgg gtagtcgctt tggccaacta
     7861 tctatatgtc aaggataatc aagtgatttt tgaaaatagt cttcaagaaa agaaaaccaa
     7921 agatcagctt aacgaatttt ttgctaatgt tcttgaaacc ccttattggt atgcaaaaaa
     7981 aatcttaagc cttttatctg agtgtttaga tcaacctgtg tatgaagagg acattttctt
     8041 tattacgcta tatttttata gtttgaatgt cacgaatgtt aaaacaggta ttaagagtat
     8101 tgtgctagct catggttatt ctacagctag tagtatggcg aatgttgcca accgtatgct
     8161 gaataagaac gtttttcaag cttatgatat gcctttagat attacattag agaaaattga
     8221 agcaaaattg attcaattcc ttggagatta tcgaacagat tcaggcttga ttttattggt
     8281 agatatgggt tcactaaacc aactaggcgg tttattagtg aatcatctaa atggaccact
     8341 gttaatcatt gatcatatca atacaccgtt attattggaa gtcggccaac aagtattaaa
     8401 caataaaagt atcaccgaaa taggagcaga aattgaaaca agtcttactt tcaaaaagca
     8461 gttactactt cccaagaaaa agaaaaagaa agccatcatt acttgttgtt atacagggat
     8521 tggtagtgcg acccagattc aggagatttt aacgaaatgc ttgaaagatg cagttagaga
     8581 attagtaatt attccgtatg attacaaaaa gctgttagaa aacaagaatt ttgagactcc
     8641 ttttcaatta tacgatgtca tcatgattgt aggtacagaa gatcccaaaa ttaatcagat
     8701 tccatatatt ggattagatc gcctgattaa tgggggaagc attggcgaat ttgttcatta
     8761 cttggaaaaa gagctgacta ttgaagtgaa cgatttacaa aaagaattaa ttttcaattt
     8821 ttcaattagt aaaattgtcg aaaatttaac cattttggat ccagataagg tgctatcttt
     8881 tgtacaaaaa gcaattaaag aattatcgaa gttattaaat tttgattttt ctaataatca
     8941 gctgtttttg ttgtaccttc actgtagttg tatgattgaa cgaattgtac gtaaagaaag
     9001 tgtggatgag caagaggaca ttgaagaata tatgcaagca aatggagaaa taatggataa
     9061 aattcatagc gctttttttg agattgaaag ggaatacaca attgaaatac cagatttaga
     9121 gttgcgatta ttgagcgata ttgttcaagg ataggagtga attcgaatga caatgggagt
     9181 aatttttgat atggatgggg tactcataga tagcgagaca ttttattttg agagaagaat
     9241 gaacttcttt caagaactgg agatagatcc aggatcaaac cagattgatg attatgtggg
     9301 gaaaacagaa gctgcaatat gggaaacatt agttcctgag gacaaatcat taagagagga
     9361 actttatccg aaatatgtag attatcgaaa aacgcatcca attgatttcg ctaaagcttt
     9421 acgaaaagaa gtgaaaccgt tacttgactt cctcaagaag cgggatatac cattggcact
     9481 ggcatcttct tctccagctg tcgagataga gagtatgctc attcaatgtg aacttactga
     9541 atatttttcc tttgttataa gtggtgagtc attaaaacaa agcaaaccac atcccgaaat
     9601 atatttaaaa gcgaaacagc aattagactg tgacttcttt attgcagtag aggattcaac
     9661 gattggtatt aaatcagcaa aggcagcaaa tatctatacg gcggcactaa aacaaccaat
     9721 gcaaatcgat cagagtgaag cagacataca aattgaaagt ctacaagaac tggaacaaat
     9781 tgttttagaa aaaggttagt gaattaatgg aaataaggct atatatctgt gctagctatt
     9841 ttgactaacc aaaaaaactt gctataattc aggtgtagta aaaggtgctg gtaacacctt
     9901 ttacgaaaat gcttcggcag tgataatggg attggctttt taagtttttt attttgttcg
     9961 caatccctaa ggtcatgtga atgatcctag ggattgctag aatattttgc aacagaacca
    10021 aaatacgaat agttatcaag cagccatatt gactgcggtc aatttaggag gggatactga
    10081 tactactgct gccgtaactg gtgctcttgc gggtattctt tacgggggtg aagtgatccc
    10141 tgaaaattgg agaaaatcgc ttcaaaatga ccagcttctt aaaacgatca gtcagagatt
    10201 ttgcgatacc gtgctatctc aaagaatttg aataatggat atgatgcaaa tcttgtttgt
    10261 actaacgttg tattgacaaa aaggatttta tttagtacaa tgttagtaca aatgatgaac
    10321 ggaggtagaa tcatgtctca atcaaccatt acatttagga ttcccgacga tgaaaaagaa
    10381 ctggtattag aatatgcaaa agcacacaat tcttcattga ccgaacttta tcgaaatgct
    10441 gtactggata aaatcgaaga tgaaatcgat ctacggactt tacggagtgc aattgaagtt
    10501 tccaaagaga aaaaagagag tggtatttct caagaggaaa tggagaaact gctaaatgaa
    10561 ttataaagtc atctacatgc cgcaagccca gaagcaatta aaaaaaatgg acagaaacca
    10621 agctaaaata attgtcgcct ggatcagaaa gaatttagaa aacacgactg acccgcgtca
    10681 gcacggaaaa ggtttgactg gaaataagag tggggaatgg cgctatcgaa ttggaaacta
    10741 tcgaatattg gctaatattt gtgattctga aattgaaatc cagatattct caattggaca
    10801 tagaagtaca atatataaaa gataaccgtt tttggaacga agtagagttt cgaaagtcaa
    10861 tgtataatct tttgaatttt gcataatacc acaggtagaa actacccgat actatcggtt
    10921 ggtttctgct tttttatggc tctttgtcaa ataggactga tagagtgaga taagaacatc
    10981 taaggtagaa ttccttttct actttagatg ttttttgatt cataggtaat cagattattt
    11041 agtaagaaaa ttctggtctt cattttccga aagcttcgaa agccataagc gactcgtttc
    11101 aatgctttga tgtgggtatg cagattttct attttggcat ttgaataagg caattcgagg
    11161 gctaaacgaa tgccggattc atagtttata aaagcttttt ttatagaatg cagttctttt
    11221 ggaacggaat tgggcatcgt tcttacaagt ttaaagaaag tgtccgcctc tttgtcgtga
    11281 aacgcttgaa gaatttcttg atagtaaaaa taggcgattc gtaattcgtc agagatcgaa
    11341 agcagacgat ccaccacttc actttcggtg agatacgccc aaccaaaatt gcgccatttg
    11401 gtccatttgt cataaacaag cttgtcctgt cgtttgatca gaagccgaga caacgccttt
    11461 aattgtcgat aatatttggc ttgtgttgga tcgtttcgat caaagctttt catgattcgt
    11521 acgcgaatat cctcaaattt acgaatgaga tgtttgacaa tgtgaaaacg atccacaacg
    11581 agttttgcct ttggaaaaca ttcctttatc agagaggcat aagaaacatt catgtccgtc
    11641 acgatgacct ttaccttcaa tcgtgcgcgt cgttcaaatt gcataaaata agaaacgaga
    11701 gcctttttct tccgtgaagg aagaatatcc agtaattttc cagtatcgcc atccatacaa
    11761 gaaaaggagt agggaccgac ttgatttttc agtgaacgaa attcatccat taataaacaa
    11821 cgcggtaacc aatttctttt tacttttgtc atggggatca gagaagcgag tgtccgagaa
    11881 acggtcgacc aagaaacgcc gcaatgctta gcaattgtcg tcattgcttg tttttcagtt
    11941 agctcttcta aaattttata gcgcacttgt ttagcgataa agcagtttct atcgacaatg
    12001 taggtattcg ccgtaaaata ggtgtggcag ccacgacagt ggtagcgttg tttcgctaaa
    12061 gcaagataag tcagttggtt cgcacattta ttaagttgaa tgagcgattt tttctttccg
    12121 ttcttaacga tcatgccttc atgattcatc tgtttacaca aaggacagcg acgaatttct
    12181 ttacttaacg tcgcagaaac aacaagactc ttgatattct taatgctctt cgattccaca
    12241 tttgtgatga aaatgttttt atctttgatt ccaagtagta gtttgatatg atgaagatca
    12301 ggcatacaga acgctccttt gattgtgttg tggtgattca attctaacgg agcttctgta
    12361 tgttttgttt tttcatgctc aaaagggacc gatagaatga ttttctatca gtcctagaaa
    12421 ttatagagcc ttttttattt ggtcttgaag aagaaa
//
LOCUS       DAXLPQ010000064        12252 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.066, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000064 DAXLPQ010000000
VERSION     DAXLPQ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.066"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..435
                     /locus_tag="ACF3UO_002316"
     CDS             <1..435
                     /locus_tag="ACF3UO_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFD3658271.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="ACF3UO_002317"
     tRNA            complement(759..842)
                     /locus_tag="ACF3UO_002317"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="ACF3UO_002318"
     CDS             1370..1870
                     /locus_tag="ACF3UO_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658272.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="ACF3UO_002319"
     CDS             complement(2060..2404)
                     /locus_tag="ACF3UO_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFD3658273.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="ACF3UO_002320"
     CDS             complement(2558..3478)
                     /locus_tag="ACF3UO_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3658274.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="ACF3UO_002321"
     CDS             3665..4156
                     /locus_tag="ACF3UO_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFD3658275.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="ACF3UO_002322"
     CDS             complement(4180..6555)
                     /locus_tag="ACF3UO_002322"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFD3658276.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="ACF3UO_002323"
     CDS             6881..7507
                     /locus_tag="ACF3UO_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3658277.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="ACF3UO_002324"
     CDS             7530..8234
                     /locus_tag="ACF3UO_002324"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3658278.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="ACF3UO_002325"
     CDS             8426..9259
                     /locus_tag="ACF3UO_002325"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFD3658279.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            9456..11384
                     /locus_tag="ACF3UO_002326"
     CDS             9456..11384
                     /locus_tag="ACF3UO_002326"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3658280.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            11522..11977
                     /locus_tag="ACF3UO_002327"
     CDS             11522..11977
                     /locus_tag="ACF3UO_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFD3658281.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            12057..12185
                     /locus_tag="ACF3UO_002328"
     CDS             12057..12185
                     /locus_tag="ACF3UO_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658282.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
BASE COUNT         3729 a         2322 c         2226 g         3975 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct tatttgagaa atgttctggt
     9301 tttttatttt ctttaataat aatcattata aataataaaa acaacatcaa gcttaatcac
     9361 caaatgataa ccattatcgt tctcatttag ctgttattat tatcaattac atttttatta
     9421 tgctatcctt gttttgacaa ggaggtctaa taacgatgac taatcagaaa aaagcttttg
     9481 cagcaacaat cggctgcctt ttatttatga tcttcggttt tatcttcgac cgattctctc
     9541 ttaccatcac cccacttttt tatatcagtg ccattatcat cggtggatat aaacaaacat
     9601 cggaaggctt gaaagaattg tggaatgatc ggacactgaa tgtggattta ttgatggctt
     9661 tagctgctat tggtgcctgt ttgatcggta attactttga aggagcaatg ttgacattca
     9721 tcttttgttt aagcggtgca ttagaggaat acacaactaa taaaagtcaa aaagaaatta
     9781 ctgctttgat gaatcttcaa ccacaaaaag cccaattatt aaaagaaaat ggacaaatgc
     9841 aagaagtaga tgtttctcaa ctaaaggtgg ataacttggt atttgtcgct aaaggagcag
     9901 ctgttccgat agatggcttt ttagaaagca cacaggcaac gatcgatgag tctgcattaa
     9961 gcggtgaatc tgtgcctgta gaaaaatatt taggcgatga gatgtatgca ggaacgctga
    10021 atcaaggaaa tcccatcacg attcgagtaa caaaaacgag ttccgaaact gtctttgcta
    10081 agattatcca attagtagaa gaagcgcaga atacgccaac tcaaacagct tcatttatcg
    10141 aacgaatcga aaataattat gtaaaattga ttttgcttgc tgttcctcta atgatccttc
    10201 tcccccactt tttcctaggt tggagttggg atgaaagctt ttatcgagga atggtattat
    10261 tagttgtggc ttctccttgt gcgcttgtcg catctgctac accagcttct ctagctgctc
    10321 tttcaaattc tgcaaaaaat gggattttaa tcaaaggcgg tatccattta gaaaagcttt
    10381 ctgaattaaa agcgattgcc tttgataaaa caggaacgct cactaaagga aaaccagttg
    10441 taactgacag ctttttcttt gatgaaaagg atttggcaca acaacttctt gttgctatgg
    10501 aacaaaaaac gacgcatcca cttgctcatg cgattttgca atatttcgat tgcacaatac
    10561 ctgaagaaat ccaatactta ccaatagaag aaattactgg ttttggatta caaactacct
    10621 atttaggtgc gcaatggaaa gttggcaagc acgcatatga tcctgagacg atgataatca
    10681 gcaaagagat tgcggaaatg atcgaacgtt tggaaaatca aggcaaaacc gtgatttatc
    10741 tttctaaaga tcagcagtta attgctgttt taggtctgct agatattcca aaagcaaata
    10801 cccaacaagt aatttcctac tttaaatccc aaaacatcca tacaagtatg ataaccggcg
    10861 accattctgg cacagcaaag gccattgctg aacaagtagg gattgaacat tactatgcaa
    10921 gctgtactcc ggaagaaaaa acacaactag tcaaaaaaga gaatgaactt taccaagtaa
    10981 atgcgatggt tggtgatgga gtcaatgatg cgcctgcttt agcagccgct tctttaggtg
    11041 tcgctatggg gcaagggaca gatgccgcta tggatatcgc agacatcgtc ttaatgaaaa
    11101 gcgacttaaa taaatttgtc tacagtcatc ggctatcttt aaaaatgcgg cggatcatca
    11161 aacaaaatat tattttttcg attcttgtta ttctcttgtt gattgcttct aacttcctgc
    11221 aatttttaaa tctacctctt ggagttgtag gacacgaagg aagcacaata ttggttattc
    11281 tgaatggctt gcgtttacta agacctttac ctgatctttc tgattcttca aaaaaatgta
    11341 agtcttgtcc actatacaaa gcgcggctgt cttctgtcaa ataagcaaag tgttttttta
    11401 tgattttgtt tattttatga aaaaaacagc ttatgaatag gtcttgaagg atgaattcct
    11461 acttttgtaa ctttctaaaa acatgttatg attgtttcga agaaagtgag gaatatattt
    11521 catggaaagt tggctttttt taggaattat tttacttgta gcaattttag ctaaaaatca
    11581 aagtctgatg atagcggcag cttttgtttt gattatgaag ctcataccag cctcccgttc
    11641 ctttttccct tggcttcaag gcaaaggaat caatattggg gtgacgatca tcacagcggc
    11701 tattctaatc cctatcgcaa caggagaaat cggtctacgt gatctattag aagcctttaa
    11761 atcccctatt ggctgggtag ctgttttttg cggtgggcta gtggctgtct tatcttccaa
    11821 gggtgtagga ttgattgctt ctgatccaca aatcactgtt gcacttgttt tcggcacgat
    11881 tttaggtgtt gtcttcttaa gaggaatcgc cgccggaccg gtcattgctt ctggtatcac
    11941 ttactgtatc ttacaagtat ttgctttagg aaaatagaac aaattttgtc tattttagga
    12001 gattcttaac acccccaatt tactgatccg tgatatactg acaacgaggt gatacaatgt
    12061 tcgaaaaatt aaagtatttc ataggaacaa tcggctggtt tcttctagcg gtacttttga
    12121 ttctgggctt agcttatcta ttatttcctg atttgataca aaatgtgttt gatactgctt
    12181 tttgattgac ctattaaaac gatatagggg atgctcctgc gatgcagggg ctttttttaa
    12241 tcaatgtttt gt
//
LOCUS       DAXLPQ010000065        12136 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.067, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000065 DAXLPQ010000000
VERSION     DAXLPQ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.067"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..610
                     /locus_tag="ACF3UO_002329"
     CDS             <1..610
                     /locus_tag="ACF3UO_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3658283.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="ACF3UO_002330"
     CDS             723..1001
                     /locus_tag="ACF3UO_002330"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658284.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="ACF3UO_002331"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="ACF3UO_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFD3658285.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="ACF3UO_002332"
     CDS             1458..2213
                     /locus_tag="ACF3UO_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3658286.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="ACF3UO_002333"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="ACF3UO_002333"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFD3658287.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="ACF3UO_002334"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="ACF3UO_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFD3658288.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="ACF3UO_002335"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="ACF3UO_002335"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFD3658289.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="ACF3UO_002336"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="ACF3UO_002336"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFD3658290.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="ACF3UO_002337"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="ACF3UO_002337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFD3658291.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="ACF3UO_002338"
     CDS             6950..7492
                     /locus_tag="ACF3UO_002338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFD3658292.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /gene="atpA"
                     /locus_tag="ACF3UO_002339"
     CDS             7515..9071
                     /gene="atpA"
                     /locus_tag="ACF3UO_002339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFD3658293.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="ACF3UO_002340"
     CDS             9085..9987
                     /locus_tag="ACF3UO_002340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFD3658294.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="ACF3UO_002341"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="ACF3UO_002341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFD3658295.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="ACF3UO_002342"
     CDS             11430..11852
                     /locus_tag="ACF3UO_002342"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFD3658296.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4036 a         2155 c         2676 g         3269 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcactaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttattt
//
LOCUS       DAXLPQ010000066        12127 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.068, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000066 DAXLPQ010000000
VERSION     DAXLPQ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.068"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..884
                     /locus_tag="ACF3UO_002343"
     CDS             <1..884
                     /locus_tag="ACF3UO_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFD3658297.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="ACF3UO_002344"
     CDS             932..3061
                     /locus_tag="ACF3UO_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFD3658298.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="ACF3UO_002345"
     CDS             3036..3725
                     /locus_tag="ACF3UO_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658299.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4133..4819)
                     /locus_tag="ACF3UO_002346"
     CDS             complement(4133..4819)
                     /locus_tag="ACF3UO_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3658300.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4955..5149)
                     /locus_tag="ACF3UO_002347"
     CDS             complement(4955..5149)
                     /locus_tag="ACF3UO_002347"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658301.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5199..5639)
                     /locus_tag="ACF3UO_002348"
     CDS             complement(5199..5639)
                     /locus_tag="ACF3UO_002348"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFD3658302.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5643..6488)
                     /locus_tag="ACF3UO_002349"
     CDS             complement(5643..6488)
                     /locus_tag="ACF3UO_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFD3658303.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLEKQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6637..8055
                     /gene="pepV"
                     /locus_tag="ACF3UO_002350"
     CDS             6637..8055
                     /gene="pepV"
                     /locus_tag="ACF3UO_002350"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFD3658304.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(8131..9333)
                     /locus_tag="ACF3UO_002351"
     CDS             complement(8131..9333)
                     /locus_tag="ACF3UO_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658305.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
     gene            complement(9320..11107)
                     /locus_tag="ACF3UO_002352"
     CDS             complement(9320..11107)
                     /locus_tag="ACF3UO_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6020 family protein"
                     /protein_id="HFD3658306.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            complement(11120..12073)
                     /locus_tag="ACF3UO_002353"
     CDS             complement(11120..12073)
                     /locus_tag="ACF3UO_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3658307.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
BASE COUNT         3931 a         2241 c         2407 g         3548 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg
     4021 tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat
     4081 tttgccgttt atttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga
     4141 tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct
     4201 cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat
     4261 caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg
     4321 aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat
     4381 cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat
     4441 caaaaaaagc ttttttattt tgagcgatca ctgcctgatc ggtttgttct agtatttttt
     4501 ctagtttagc ttgatcttgc ttggtcattt tcgcactgca ttcttgcagg atcggttttt
     4561 ccaacttttc ccgcgtataa cgggctaatg aagcagatcg gatatcgatt tttgaaacat
     4621 aagtgccgga ctgtggaatg gtttttacaa gctcttgatt gcgcagttgg atcagtgctt
     4681 ctcgaatcgg tgtacgcccg atagctagtt gttcttctaa cactttatcg gagattttac
     4741 ttccaggtgc taactcggaa taaatgattt gtttacgtat agattcataa gcttgctgtt
     4801 gcaaattatt gataaccatt taaccttcct ttctatgcag atataatcta ttataacata
     4861 aatcgcttac aaatcgtgtg ggcataaaaa cacagtctgc aaaaaaagcc ctgataggca
     4921 tgcctattag agcctcgaaa agaaaaatat tgaatcaatc tggtcgtacc tcttggatcg
     4981 gtttgacacg accgccgatt cttttagcaa aagcttcgga ttcttttttg tctttgaaaa
     5041 tgagcagatt gtctaagttt ttttcccgag tgcgacagcc agttttatcg atgtaaccgt
     5101 gcattacttt aacgacatac atggggatca cctgcttttt tcttttcatt atacgaacta
     5161 ctcgacacaa tacaagaaaa atgcttagac ggtctttatt aagaatttac atcatccaaa
     5221 gaagcgtacg cttggaataa ctgttctaac tccggattga ctttgctcag cttcactaat
     5281 cgttgcgaat cagaaagtaa aaaacagtgt ttactactgc cagtagtttt taattttttg
     5341 tcttcagttc ccacaatttc gtagctaaaa tccaaccgtg ttcccgtata cttttggata
     5401 gttgggtgga tgctcacttt ttctccgtaa tggatcattt ctttatagct gcaatttact
     5461 tccagaacgg ggatgatgat cccagattct tcgatttttt tatagggaaa ccctagatgt
     5521 accaataagg ctacccgagc ctcttcaaac cagcggatat aattgctgtg atgaataatc
     5581 cccatttgat ctgtttcata ataaaaaggt tctcgcacat aacctgtaaa tttctccatg
     5641 actcatgcct cgttttccat tgatttttta caaaaataat tcatccactt cggaagtgct
     5701 tcgctgattt gtgtcggcaa aacaatatat tgttcttttg ccagctggtc tccaatgaaa
     5761 ctatgaagat aaacagctgc tgcaatcgtt tggtcatttt gaggaaactg ggctaaaaat
     5821 cctgtgatca tcccagctaa agtgtcaccc atgccgcctg ttgccatagc agcagaacct
     5881 aaaggattgg tgtagaagtg ctggtgacca taaatttttg tctcatgact tttcaaaacg
     5941 agcacagcac cgatttcctg ttgcttcttt ttgttttctt tatcccgttg ttcttgtatc
     6001 ggtagagaac tcaaccgttg ccactccatt tgatgaggtg taagtacagt ttgttcggga
     6061 tagggtagca aaagatgatt agcaacaagt aaacttaaag cagagccatc aatcaccagc
     6121 cattgttctt ttgattgttt ttctagtact tgtttgaaac gttccaaact cttagaagaa
     6181 gtacccaatc cgggaccaat caagagtaca tctgcttgct ttattacgga aagaaactgg
     6241 tcagtatccg tccaatctac aatcattgct tctggcagat gactgtgaag agcactccga
     6301 tttttttcat cagttactac agtcgtgaga cccgctccac tgtgtacggc agctaaagca
     6361 ctcataatga ttgctccgcc atattgttca ttgccgccaa tcaaaacgat acgtccaaat
     6421 gttcctttat gtgaaatctt tggacgaggt gtgatgactc ttttcactag ttgttcgttt
     6481 atcagcatcg aaaaacctcc ttttactcat tatagcgtat atttttttta gagaaaaaca
     6541 gataagaaaa ggaattgtca gattttttga actatttttt tctgtaattt gtggtatcat
     6601 gaacacgaag acttaaataa gtggaggatt aactttatga caattgattg gcaaaaagaa
     6661 gtagaagcac gtaaagaaga cttgcttgaa gacttgaaaa atcttttacg tgtcaacagc
     6721 gagcgcgatg attcaaaagt aacaccagat gcaccatttg gacctggacc tcgcgacgca
     6781 ttgaaacata tgttagctta tggcgaacgt gatggattta aagtaaaaaa tgtcgataac
     6841 tatgcagggc atattgatct tggcgaagga gacgaaacgc tagggatatt tggacacatg
     6901 gatgtcgttc ctgcaggaga tggctgggac acagatcctt atgaaccagt aatcaaggat
     6961 ggaaagatct ttgcacgcgg atcaagcgat gacaaaggtc caagtatggc agcttactat
     7021 gcgatgaaga tcattaaaga acttgacttg aaactatcaa aaaaagttcg cttcgtagtc
     7081 ggcagcgatg aagaaagcgg ctggggcgat atggcttatt atttcgaaca tgaagaagaa
     7141 ccagattttg gtttctcacc agatgctgaa ttcccaatca tcaatggtga aaaaggaaat
     7201 gtttctttag ctttacgctt caaaggcgac aatgcaggag attatgtctt gaaatctttt
     7261 gtttccggac ttcgcgaaaa tatggtgcca ggaacagcaa ctgcagcact tcaagtacca
     7321 agtgcagatg cagctatcgc gatggaagaa gcattttacc aattcatcga agcaaatcca
     7381 gtaagcggaa cgattgaagc ggacaatacg tatgtaaaaa tcgaattagt tggtaaaggc
     7441 gcacatggtg caagcccaca atctggtatc aatgcaggtt ctttcttggc attgttctta
     7501 gataactatg aattcctagg atctgctaaa caatttatcc atgtagcagc tgcttatgtc
     7561 catgaagatt tttatggaga aaaactagga gtcgcttatg aagatgaaaa aatgggcaaa
     7621 ttgacaatga atgctggact atttgctttt gaagaaaatg gtacagagga agcgaacttc
     7681 atcaatatga atttccgttt tccaaaaggt gtaacagtag acggattgca aagtgacatc
     7741 gaacaaacag tggggcaaga aggcgcaaca gttactcgag gtgctcgcgt aatggaacca
     7801 cattacgtac caatggatga tccattggtg gctacattat tgcaagtcta tgaagaccac
     7861 actggagaaa aaggctacga acaaatcatc ggtggcggaa cttacggacg tttgttgaaa
     7921 cgtggcgttg cttatggagc gatgttccca ggatatactg atacaatgca tcaagcaaac
     7981 gaatttatga gtcttgatga cttgttcaga gcaacagcaa tctatgcaga tgccatctat
     8041 cgtttggcga aataaaaata ctaaaaaact ccggctatct ctgacagctg gagtttttat
     8101 gtttaaaaat gaattagtac atcggtattc ttaaaagtaa tttagttcgt cttttgattt
     8161 ctcaggaggg atcaaaaagg cgaaagcact aagtatagca aaacttgtga tgatttgcgt
     8221 acgatacgta aaccaataat gaatctgtga gtgattagct aaaatattgt accaaatata
     8281 cggcgttaca gcagctaaaa caaacaaaac tagaagttgg aacggacgcc agctatttcg
     8341 tttacgataa gcaaaataga gaaaaacaag acaagtaatc aatagcaata atattgctac
     8401 ttttggatac atcaatctaa tattgctttt cagcatctct aatcgatgca acgggtattt
     8461 gtcgtttcct tccgttcgaa agaggatttg gttgattgca tcttttacaa tgtttttgtt
     8521 caatatgatc gatgatagga tccatttagc cacccatgtc aaaccatagc ctaatcccca
     8581 aaagataccg gtaaaaacaa aactgcctac ttgtttgctc aatgaactgc gtttatccat
     8641 taaatactta tttgttacat aataaataat gatcacaggt atcccccaag agatgaccgg
     8701 tgttgtcaac aagtcaaaaa agttagctaa agaaccaatg acaaagaaat acaagaataa
     8761 ttgttggttg gtgttggaga gttgtggttt tgttaaaaat agtaatacag acaataaagt
     8821 caaaatccaa atatttgaaa attgcatact gaagaaaaag gttgcagcat ttcctatagc
     8881 aagcgaaatc aacaaggctg tcgttaaata gatgtcgcta cacttggtta aaaagtagct
     8941 cgtcaatcca atcagcagaa aaagaatggc tgcgtaaatc attcgaatac tccccaaact
     9001 catccctagc agtaaaggtc gtaaaaaaag ctgataacca tgccaataac ggggataatc
     9061 cgccatagac atcgcgttct ccaaggagtt caattcagga tctgcttttg tttttcgtat
     9121 catcaaatga tcagtaaaat tatctaaccg agtgcctagc atatttcctt gattgataga
     9181 aggatacatt ccttcttttt caaccatctg tagagatttt tctgcattcg attcaataga
     9241 gtgctgcgga atgaaaaaag taattgtcag tagtacgcaa tagctagcga tcaagagaac
     9301 aaaagcaaaa aatatctttt taaatagttt catgagtatc tcctatatct gttttcattt
     9361 tttctctttt atctagtaaa aaaggagaga ggatataaac aggtagacct aatgctaaaa
     9421 caaacacata ccgtaaacta aaagccacag gagtagcaat cataatagta gcaaaaacaa
     9481 gcataccggg aagaaaaagg agtaaatacc gatatttttt cttaaagatt gctaaaagtg
     9541 cactgccgat agctaaccac agtaatgtgc cggaaccaaa gaaatcacga gcatcgatga
     9601 tttttttcat tcctgacaat ccagtaagat gttcaatcaa atctacttgc ttcatcccat
     9661 aattattcgt gtttacacga gtatctaaaa agccgtaact attttttgta ccaggtaccc
     9721 agaacccgaa cgtttctaaa atataagcat ctgtatagat ttttatatta cttggtaaat
     9781 ttcttgccca tagtgataga aattcttttt tatgtgtatt caaaaactca ttgttaaaat
     9841 ttttatgcca cttgattgag tctgcaagac taggagaata cgcttcataa tcttttatcg
     9901 ggagtagctg attcatgaat gctttatctt tcttagacaa gtcaccatcc ataacaatag
     9961 ttctagaaat ttgctgcaaa ggaacaccta attgttcagc agtttctgta ggaatagcat
    10021 aacgagccat caacgggtgg atgagtagtc cagcaatcac tgtataaccc agcaccactt
    10081 gaaagaatgc ttgatacctt ttttgtttca aaataatcaa gccgcaaatc aaacctgtgc
    10141 cggttactac ataaatccca ttatttctta gataggtggt cagtaaagca aggatgatta
    10201 cgtaaatctg attgagaatc gttggctttt ctcgttgaaa aataaagtca aaaaccgcta
    10261 aggaaaataa aaagcaagcg atagagaaca aagtatcttt ttgcatgttc aaggcgtaga
    10321 ttggaaaaac cggtgcaaat gcaaaatagc ataaactaat gagtaccgga aaaaaatgga
    10381 tgtttctttt taacagccag caaagagaat aacttatcgc tgaagctgtt atcaatgttt
    10441 gaaaaatcga aaataaaaat acaccgtgat tgatcgtatc agttggtaaa tcatgaacaa
    10501 atagcttgac cagtaaggtg aataagactg gatgatgatt gcttatagga acatcaccca
    10561 tagattgggc gaccgaactt aacgaatcag gcaaaaccac tccaggatac aatgccaaca
    10621 gataaggaag ccaacacaga actaaaaaga cagtaaagaa taaaaaatat tttcttgaag
    10681 agaaagcctg tgtgttttga gcagtaaaaa atgtttccag ttttggcatt gataaataaa
    10741 tcgattgtaa aaataaaaaa gaatacacaa aaatggagaa ataaacaaga aagtaaaaaa
    10801 tacttccatc agcaatcgtt gtctttgtat agtttgctga gacatactga aattgtatct
    10861 gtctgccaat agaaagtgta agagcaaaag ctgcagaaaa aaacaatcgg gcaatagctg
    10921 caactttgtt ttttattgaa aacaactcta ttccatattg cttaaaagca agtagcaaaa
    10981 ccatggctaa accaatgatt actgttggat tcaaagttcc tagaccataa gaagtaaaaa
    11041 aagcaaaacc tgacgcaaat aaagttgcaa aaaaagtagg aaatagattc tcctttttct
    11101 tatgcataaa aaaggcctcc tacttcattt ctttattttg atattcgtgg tagacatggt
    11161 ataaattcaa ttcatattct ttcttggcat ttgtgacgac cgtatccaaa atcaaccctg
    11221 ttactaatga aagaagggct aaagtcatca atccagtact taaaatcgca gaagggatgc
    11281 gtgtaataaa gcttgtcagc atatattcac gaatcacagg aatccccatg accaatccaa
    11341 ataaaaagaa gaagatggtc cagatcccaa agaaaagcaa aggtttataa tctttgcaca
    11401 ttttgatgat catcatgatc actttgaatc cgtcagagaa tgtattcaat tttgattcgc
    11461 taccttcagg acgatcgcga taatcgattg gaatctcaac gaacttgaat tttttatcta
    11521 aagcatgaat cgtcaattct gtttcgattt gaaaaccaga actcataata gggaagcttt
    11581 tgacaaaaat tcgattgaat cctcgatagc cggtcatgac atcgcgaatt tttgttttat
    11641 ataagtaagt aattgtattt ttaaccagat tattcccaaa atcatggaaa ggacgcttat
    11701 tttcatcaaa ataggttcca tttgatagac gatcgccaat gaccatatct gcttcgccag
    11761 aacgtaattt ctcaagcaaa ccatgtgcag cttctgcagg ataagtatca tcaccatcta
    11821 ccatcaaata ataatcggca tcaatatcaa aaaacatttg acggattaca tttccttttc
    11881 cttgacgtgg ttctttcttt acgattgccc caccttgaac ggccaattcg tatgttcgat
    11941 cggtcgaatt attatcatag acataaatat ctgcttctgg taattccctt ttaaaatctt
    12001 caataacagt tgaaattgtc gcctcttcgt tataacaagg aatgagcacg gcaatttttt
    12061 cacgtgattc catttgtcac tctccttata taataaaact aatcttattt caagaatacc
    12121 atataat
//
LOCUS       DAXLPQ010000067        12093 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.069, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000067 DAXLPQ010000000
VERSION     DAXLPQ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.069"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..260
                     /locus_tag="ACF3UO_002354"
     CDS             <1..260
                     /locus_tag="ACF3UO_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658308.1"
                     /translation="LKRKVTDRNKNLLNVVMICYISFLILGLPQAVFPEMFSGDWGIV
                     SYSILTLIAMVLGTSFYNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..655
                     /locus_tag="ACF3UO_002355"
                     /pseudo
     CDS             467..655
                     /locus_tag="ACF3UO_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1367..1972)
                     /locus_tag="ACF3UO_002356"
     CDS             complement(1367..1972)
                     /locus_tag="ACF3UO_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658309.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2154..2489
                     /locus_tag="ACF3UO_002357"
                     /pseudo
     CDS             2154..2489
                     /locus_tag="ACF3UO_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2654..2869
                     /locus_tag="ACF3UO_002358"
                     /pseudo
     CDS             2654..2869
                     /locus_tag="ACF3UO_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3007..3978
                     /locus_tag="ACF3UO_002359"
     CDS             3007..3978
                     /locus_tag="ACF3UO_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3658310.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4118..5431
                     /locus_tag="ACF3UO_002360"
     CDS             4118..5431
                     /locus_tag="ACF3UO_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFD3658311.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5474..6340
                     /locus_tag="ACF3UO_002361"
     CDS             5474..6340
                     /locus_tag="ACF3UO_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3658312.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6337..7185
                     /locus_tag="ACF3UO_002362"
     CDS             6337..7185
                     /locus_tag="ACF3UO_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3658313.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7199..8671
                     /locus_tag="ACF3UO_002363"
     CDS             7199..8671
                     /locus_tag="ACF3UO_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFD3658314.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQKRIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8688..9560
                     /gene="scrK"
                     /locus_tag="ACF3UO_002364"
     CDS             8688..9560
                     /gene="scrK"
                     /locus_tag="ACF3UO_002364"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFD3658315.1"
                     /translation="MIYGSIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9795..11176)
                     /locus_tag="ACF3UO_002365"
                     /pseudo
     CDS             complement(9795..11176)
                     /locus_tag="ACF3UO_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11638..11961
                     /locus_tag="ACF3UO_002366"
     CDS             11638..11961
                     /locus_tag="ACF3UO_002366"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFD3658316.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFSK
                     KSILV"
     gene            11993..>12093
                     /locus_tag="ACF3UO_002367"
     CDS             11993..>12093
                     /locus_tag="ACF3UO_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3658317.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQE"
BASE COUNT         3757 a         2063 c         2434 g         3839 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgagat cctagataaa attaaacaga attgatcaga
      661 aacaagcgaa gccttctctc ggttcgcttg ttttgctatt tattagttgg ctcagggcaa
      721 ctctaagctc gtttgaaaga aaaccgatgg ataatcccct tgtttgtacc actttagaat
      781 acatggatgt acgtattgcc attgactcct attagttact gaaaaaaaat ttaaacaagt
      841 tgagtattgc agataaatag ctccagtgag gtgaataact gctccactca aggcaataga
      901 tagctccatc cagggcaaca aactgctcca ctttcatatt taatagatga ataaccttct
      961 gtataataga aaggcatacc tttcggtatg acaacttata cagaatgtta ttttattggt
     1021 tcactatcga aaaattttgg agctttattt ttccggtatt tctcaacgaa cgattagttt
     1081 aactgtggga agctccagac atacgattcg agaagttact tctcgagcag acaggaaggg
     1141 ggtgactgaa ctaaccgctg atatgagcga tacttggctg taggaatatc tttttccgga
     1201 aaaacaaaca acagcacgag gttaccttcc tgtagactgg gaatatgttc ataaagaact
     1261 aatgaaaaag aatatgacat tgaaactcct tcatagagaa tatggggtac atggaacata
     1321 gaaacgaaaa tgcacggtag aaaagcgaat gaatatagta taaattctac aaatcattcg
     1381 ctttctttat tttatatatg gttggtcgag agagaccatt ttctttggca atttctgcaa
     1441 ctggaactcc ttgatttaac atgtccacca cagttttaaa gactaatcgt ttttgcggat
     1501 ctgttgagtt ctcagaatat tcaattggtc gccccttata tcgaccagct tttttggcca
     1561 ataatactcc ttgccgctga cgttcacgga ttttctcacg ttcgttttgt gcaatataac
     1621 ttagcaatga taaaaacata tcgaacatag cagtatctag gagttcattt ccagtattaa
     1681 aatctaaaaa ctgtgcatct agtattttta atgctacttt tttctgtttc ataaaggtaa
     1741 ctgtattttt tatgtcttca taatctctgc ctaggcgatc cagtgatgca acaatgacac
     1801 aatcaccttc tcggatataa tttagtaatt tttgaaactc aggtcgctgg atatctttac
     1861 cactggcttt ttcttggaat aatttatcaa tgttaaggtc ttccatcatt gccaattgtc
     1921 gatctaaatt ttgatcttgt gaagacactc taatatatcc aatttttgcc ataaaaactc
     1981 cttttaaaaa atgatataat ttacatgtaa aatttacttg tagttttact gttatcatag
     2041 catttttaaa aataaatttt aagtctactt ataatttact ttggaggttt tgaatgaatg
     2101 aaattaagcg caataaaaat tcttttggtg tttatttagg agagcctagc tcggaacagt
     2161 taaataaagg tgaagctcgt catgctctat gtcgaaatat attttatggt agaaaaggca
     2221 aactttatca aacttattac gacggtatgg aggaacagct caacgcatta ggattagtaa
     2281 ctaatgctat catatattgg aattcactat atttagaaaa agtctttgaa caaattaaaa
     2341 cggaagggtt cgactgttcc gaagaagtgt tacgcaagca atttccatta attagtgatc
     2401 acattaattt tgttggcaaa tatagtttcc gctatgaaaa agaattatcg aatggaatac
     2461 tacgtccgtt aaatatagag aattattgag aatgttcgtc ttttggttcc taccgtgcat
     2521 tttcgcacgg atgttccaga tactattttt gaatgtataa aattgaaaac acaagaatac
     2581 taataaatca acgattcttg tgtttttaat ttttcactac cgtgcatttt cgtttctatg
     2641 ttccatgtac cccaatcttg aaaaattaat taaagactta gataaagcca ttgacgactt
     2701 agtcgtggtg ctaccggagt atcaatgttt aaccagtatc ccaggtattg gtcctgttta
     2761 ggctgctgga atactcgctg aaattggtcc aattgaacgt ttttctgatg aaataaaatt
     2821 gacaaagtat gccggcctat attggcgaca gagtcaatcc ggtaaatctg aatacgaaaa
     2881 tttttttacg aaaagcttca cgtctaatat ctattttaaa ataaaaatat tcctgctaat
     2941 ttggaatcgt ttccttcttt tggtataata atacctgaaa ttcttttgag aggagttgtt
     3001 cgtgaagtga aaactactat gaaggatgtt gctgcgttag caggagttgg tgtgggtacg
     3061 gtatctagag taataaatgg agtaaaggtg aaagaggtta ccaaagaaaa agtaatggct
     3121 gcaattagtg agcttaatta tgagcctgat gaatatgcca gaggtatgaa aacgaatagt
     3181 agcaatacaa tagctcttat tttacctacg atttggcatc ccttcttttc cgagtttgcc
     3241 tactatgtag aggaagctct cagccaaaaa aattataagc tttttttgtg taatgcgaac
     3301 ggcagtgcgg aaaaagaaaa agaatatatc caaatggtca agcagagtaa agtagacgga
     3361 attataggta ttacctattc agacattgat aaatatgtat catcaaattt accatttgtc
     3421 agtatagacc gccatttttc ggaacaggtt tcttatgtaa cggcagataa ttatttaggt
     3481 gggcaaattg ccgctcaaga actacttact cgtaactgta aaaacttgtg ctatgttggg
     3541 ggtgtttcac cttaccctaa cgaaacaaac aatcgtaaag ctggttttta caatatttgt
     3601 gaggaaaata aaatagctgt gaaggtattg gatatgcctg aaccaattag caatttagag
     3661 gaacaattgc tcgctttttt ttcggataat cctgaaattg atagcatttt taccatcaat
     3721 gatttcatgg ctttggatgt gataaaagcc caaaaaaaac tagggaagga agcacctaag
     3781 gattttcaaa ttattggttt tgatggagtc aagctatcgt tgcaaaaaga ctatttacta
     3841 tcaacgattg tacagccgat agaggaaatg gccaaggttt cagtagaaac actcatggcg
     3901 atgattttaa atgaagaacc gcctaagcgt gtggtagtac cggttttctt tcacgctgga
     3961 gagacgacta aagagtaaaa aaccggttta taacgatttt tttgagatag gttgacagaa
     4021 agtgatttca atgatatctt aaaaccaatt aattggaaac gttaccaatt aattgaaaaa
     4081 taaaacggaa acgtttcaaa aaataggagg aacatcgatg aaaaagagaa tgttagcaat
     4141 tgcagcaatt ttagcattaa cagctggagg acttgcagga tgtggcagta aggagaaaag
     4201 ttcaggtagc agtgatccag gagaaattaa gatttgggtt cagttttctg atgaaacgcc
     4261 tgaaggaaaa gcttgggcag agattgtgaa caattttaat gatgaatacg agggtgaata
     4321 taaagctgtt actgagtata ttcctcgtag cggaagcggc ggtggatatg aggataaagt
     4381 aaatgctgca attacaacca atacccttcc tgatgttatt acgttagatg gaccgaatac
     4441 tgcagcttat gctcattcag gagtcattgc tccattagat gattatttga aagatgcgga
     4501 catggatgat gtattagaca gcattattca gcaaggaacc tacgatggca aaatgtatgc
     4561 gtttggtttc tcagagtcca gtgtgggtgt ctattacaat aagtcgctgt tcaaagatgc
     4621 tggaattaca gaagatcaat tgccgacgtt agaagatcct tggacttgga cggaatttca
     4681 agcaatttgc caaaagctga ctgataaata caaaacgcct gcaattgata tgcaaatggc
     4741 gtcgggagac gaaatgctga cctacgcata tacaccattt atatggtcga atggcggcga
     4801 tgtcgttaat gctgatggaa ccaaagccga agactatttt aacggtaaaa aatccgttga
     4861 agcgttggaa tttattcaag aattggttga aaaaggttac accacaatca gtcctattga
     4921 aaaaggattt gaaactggca aatatgccat gatgctgagc ggttcttgga caatggcaga
     4981 tttagaggaa aactatcaag agattgatta tggtattttg ccttaccccg tttcagatgc
     5041 aactggggag ttagtttcac caaccggaag ctggcagtta gcaatgactg agaaaacaga
     5101 gaaaaaggat gcttctgcgg cctttattaa gtttgcaacc agtacagaat ctagtcgtat
     5161 tatgagttta gggaacagtg ttctacctat cagaaattca acagttgatt taattaaaga
     5221 tgaagtgtcg gaaggaatgc aggtattaat taagcaaaac caactttctg gacatgcccg
     5281 cccagtggtt gtagcttatc cgcaagtatc tagagcattc caacaagcag ttcaagatat
     5341 tagctacttc gaggaaaacc cagatgtaca aaaagtagca gatagtcgcg ctgctgaaat
     5401 gcaacaggca attgatactt cactaaaata gaagtttcta aagggggcca atcaagtgtt
     5461 aaaaaaaccg acaatgaaag acaatttgat aggttacggc tttctagcgc cagctttgct
     5521 gctgctgacg atttttctga tcatacccgt aatcatggta atttattatg cctttactga
     5581 ttattatttg ttaacgccag atgctagaca atttatcggc ttagaaaatt ttaagcgact
     5641 gttcgctgat ccaatttttg taaaaagtat ttggaacacg gctaaatttg ttgtttggat
     5701 tattccggtc caaatagggg cagctttagg aatggcactt attatcaaca aaaatcgtaa
     5761 aggaaatatc ttttttaaag tagccttttt tgcgccagtc gtgatgtcct tagtcgttat
     5821 ttcgatttta tggttgtact tgttaaatcc taatgaaggt ctggttaata cgctatttgc
     5881 aaagattgga attgcttcgc agcctttttt gactagtccc aaacaagcaa tgtatacgct
     5941 tgttttcgta tcggcatggc aaggtgcagg atatcagatg ctgctgtttt tagggggaat
     6001 gcaaaatatt ccgcaagacg tttatgaggc agccgaaatt gatggttttt ctaagtttca
     6061 gcaatttcgc tatatcacca tgccattatt aaagcccacg gcgattttta ttttacttac
     6121 cacattgatt tcggccttta aactaatcat tcagccaatg gtaatgactc aaggtggacc
     6181 aatgaattct actatgacaa tggtttatta catttaccaa actggattta cagaccgtat
     6241 ggtaggctac tccagctcca ttgcgttaat ctttaccact atgattggtt taattacaat
     6301 tgctcaaaga aaattggtaa aggaggatga tccagcatga ccaagaaatt tggaccgcta
     6361 atgatcgtag aatattgttt gctgttcctt ttagcggcat tattcatttt cccgatgctg
     6421 tggatggtag tttcctctat gaagcctgaa gcagatgtct atcaaaattt agcttccttc
     6481 aaagcttttt tacctagttt gaatccagct aattggttta aaacttatca agaggttatt
     6541 tcccggttca gtgtgggaac ttatttatta aacagtattt tttatggttt aacctttgcc
     6601 tgtgggtcaa tcattgtaaa ctctttggcg ggttttgcct ttgcgaaggt taatttttca
     6661 ggcaagaaaa ttatctttgg agctttgtta gctctgctga ttgtcccgat ggagacggtt
     6721 ttaattccgc aatttaccat cgttaattca ctaggcttag tgaatactcg cttggcagtg
     6781 attttaccag cgatggccag cgcgtttaat atctatctgt ttagaaattt ctttatcgcg
     6841 attccagaag aaatcattga atcagcgaaa ttagatggtg caaatattgt taaaattttc
     6901 tttcacatca tgctgccaat gtctaaacca gccatagcca cagtaggtgt cttatccttt
     6961 atctccagct ggaatgatta tatttggccg ttaatggtct taactgacag cagcaaattt
     7021 tcaatgcaag tggcaattac tacgatcaat actacacagc cagtttatat caatcaagtg
     7081 atggctgttt taaccattgc aacgattcca ctgattattg tttatatcgt tgcacaaaaa
     7141 tatattctgc agggacttgg cggttctgga acgggtataa aataggagtg aatagtgaat
     7201 gttgcaaaaa cttttaaagg ccaatgagtt tattgagaaa aatgctcaaa cagtcaatca
     7261 agaataccgg aataaatttc atttgatggc tccgattggc tggatgaatg atccaaatgg
     7321 ttttgtttat tatcaagagg agtatcactt gttttatcaa tattatcctt acgacagcat
     7381 ctggggacca atgcattggg gccatgctaa aagcaaggat ctaattcact gggagcattt
     7441 gccagtagca ctggcaccag gtgaaagcta tgacaaggaa ggctgttttt ccggcagtgc
     7501 catagaaaag gatggcaagc tgtatttgat ttatacagga cacaatgttg tggaagggca
     7561 agttcgacaa gttcagtgtt tggcagtttc agaagatggc attcactttg aaaaatatgc
     7621 cggaaatcca atcatcgcag aagatcactt agcttctgtt gcaacgaccg aagatttccg
     7681 cgatcccaaa gtgtttcagc gaaaagaaga ctattttact gtagtcgcta ctaaaactgc
     7741 agatgctcgt ggacaaattg tgatgttcca ttccaaagat ttactaactt gggagtttta
     7801 ttccgtattg ctggagggaa ctccagaaca aggcattgta tgggaatgcc cagacttgtt
     7861 tgaactagat ggcaaagaag tcttgattct ttctcctatt caaatgactc cacaaggcaa
     7921 tgcttaccaa aatacgaact caactgttgc tttcatcggt actgtcgatt ggcaaacagg
     7981 caaatttcta gtagagaatt ttcatgaaat cgatggcggt ttagattttt atgcacccca
     8041 gacctgtgaa aacgaagcag gccaaagaat aatgattgct tggatgcaaa tgtggcagcg
     8101 taaaatacct acgaatgatc tgggccatgg ttggtcaggt tccatgacct tgcctagaga
     8161 gctgagggtg gctgataatc aattgttgca acggccagtt tcatcaattt atcaagtaat
     8221 tgatccgcag aaaaggattg aatgggcgaa gactgaagag aatcgcttct tactgaagga
     8281 cttagtatat gaccagcact atttacgctt ggaaatcaat ttaaaacagg caacgaaact
     8341 agaacttcac tatgcgaagg gacccgacca tacattactg cttaactatg atgttgaacg
     8401 ggagtgcttt actgcttcca gggaacacat gccgtatgat ttatcaggag ctgaaaagga
     8461 agtgttgaaa aagcgcagtg tgacgattcc tttggaaaat aattgtctaa ccatcgaaat
     8521 tttccgtgat acttcagcta ttgagctttt tctaaatgat cgtctgacta tgagtacaac
     8581 tttttatgag acagaaaaag gacaggattt tcttttgctg gcagacagtg aagtaacctt
     8641 ttcattggaa agcggcttaa ttaatctata gaagggagag ctcagtgatg atttatggtt
     8701 caatcgaagc aggcggcaca aaatttgtgt gtgccattgg cgatgaagaa atgacgatca
     8761 aggaaagagt gagctttccg acaacgacac ctgaggaaac aataccttta gtcattgact
     8821 tcttcaaaca ataccaagca gatttagcag ggattgggat tggctcattt gggcctatcg
     8881 atatccatcg cgattccgcc acttatgggt acattacctc gaccccgaaa gtggcatggc
     8941 aaaattttga tttcatcggt accatgaaaa aagaatttcc gatcccgatt tcttggacaa
     9001 cagatgtcaa tgcggctgcc tatggtgagt atgtcttcgg cagtggcaaa ggattgagca
     9061 gtgtcgttta ctatacgatc ggtacgggtg ttggcggcgg tgccttacaa gaagggcgct
     9121 ttatcgaagg gtttagtcat ccagaaatgg ggcatatgct cgtcgtccct catccaaaag
     9181 atgactttgc tggcagctgt ccatttcatg gcaactgttt agaagggatg gccgctggac
     9241 ccgccatcga aaaacgctta gggaaaaaag gacaagaggt tgcagaagat gatccttatt
     9301 gggaaatcga agcctcctat attgctcaat gtgcctacaa tacaaccttg atgttttctc
     9361 cagatgtgat catttttggc ggtggtgtga tgaaacaacg ccatatgctg caaaacgtcc
     9421 acgacgcatt tgcaaaattg gtcaatgggt atgtcgaaac acctgagtta agcaaatata
     9481 tcgtgacccc agcattagaa gacaacgctg gaacgctcgg ttgtttggca ttggctcgag
     9541 aagcggtctt acattcataa acgaaaaaag gctcttcgac atttagtgtt ggtagagaaa
     9601 gatacaactg aaaatttagt cataaccagt taggcagagt gcttaactgg tttttgtttt
     9661 acttggaaga tcaagccttg aatgagataa attcttgctc gaaagttatg gaaatttcga
     9721 tagccgtagg ccacttgtat tgtgcaatag ttttttacaa aaaaaagggg gtgcggatat
     9781 ttttttggac ctttttaaca aatatatctt tgcttcttcc gatattgaag agggcttagc
     9841 cctcctaaag ataacttaat tcgttgatta ttataccaat gaatataatc atccaatttg
     9901 tttataaact gattgattgt tgtattcttc cagtcacgtt gataaaacat ctcgtttttt
     9961 aatcgtccaa agaaaccttc gcacgctgaa ttatctggtg aataaccctt tttagacata
    10021 gagtgaagca agttggcttt gttccaatag tccaactaac aatagcacca tcgtaacaat
    10081 cgacaagtgg tgataagtag attttccctg cgggaattct aaattcagta atatctgtta
    10141 accatttttc atttggcttc tttgctttaa aattccgatt taataaattg gggtgtgcag
    10201 gagaaatttc cccagcatac gaagaatact tttttcgtct agaaaattta acaaatagat
    10261 tttcctcagt catcaatcta cgtacaactt tttcagaaag ctttttaccc atatttttta
    10321 aagcttggtg aattctacgg taaccatacg cacagaagtt atgattgaaa atcgtgataa
    10381 ttaattgacg ttctttgtaa tacttatctg gtttctcaag tgcttgtttt tgataaaaat
    10441 agctgctttt aggcaactgg agctgttgaa gaagctcttt caaggtgaac tgatttcgta
    10501 aggcatcaat caatatcgtt ttttcttgat ttgatagaca aagaagattg acgccttttt
    10561 ctttttttag cagttcagcc gctccttcga gtaatgtttt ttcgagctgt aattggtgta
    10621 cttgtttttg taagtcttct acttccttta aaagtagctc tttttgtttt tcctgatttt
    10681 ttaaagtcat acgcaatgga aaatcctttc caagaaccgt gtttttccat tgatatagag
    10741 taactctact aattccttca gattctgcta aatttttcct attagtttgc ggtttataga
    10801 attttttcaa cacagcttct ttttgatctt gtgttaactt taccgcactt tttcggagtt
    10861 ttctagctcc tggtgcaagt tcttcacacc gctgccgcaa ggactctcta ttaggataac
    10921 caagcatgcg aatggttcgt gcataacatt gaccatattc aaaataatga ttcaccgcta
    10981 ttcgtttttg ttcttcagaa tactttgatt tttttcggtg ctcctgatgg agctctccgg
    11041 attccaaata ctctttatac catttccgta gtgcaccaat cgacggatac cctaattctc
    11101 gaatggttgc agcataagag caatcgtatt ttaaaaataa ctgaattgcc cttacacgct
    11161 ctttgtggga aaacacacgg acattcctcc taagtttatt ttttcgtcca ggattatgtc
    11221 cgcaccccct tgctttctga tgacttattc tggttctttg agtgtcaatg catagatgtg
    11281 atgtagctag ttagaaaaaa attttgaata ctcttttttt ctttcagact cctttttaag
    11341 taagattttg aagtgtgagt tacggggtca gaaacttaaa agtttttgat cctttatttt
    11401 caagtctgat ttggcagctt ttcggcagct catttattta tggtcagaaa tagatgctga
    11461 aattttaatc tattagcaaa tagtccagaa cgtatgaaga ggagtcggat atcatttgtc
    11521 attaacacca taaatattta taaaattcgt gttcacctac aattaaattt aatatataat
    11581 attcgttgta agggcttata attttttgtt aatgaacaag ataggaagaa acatttaatg
    11641 gacagttttc agagattgtc actagtaaat caatttgagt tattggctaa atttgaggac
    11701 caaaacagat cttattatga aagaaaaatc gaaatattga gagaaggtta cgagtatcat
    11761 tatgatgatg aaatttggag tgatctttct gagccatttc cgaaagaaga ttctcgattt
    11821 gtattagatg tattgaacat gtatcgagat atcaatttta gtaaatcaaa gctaaactta
    11881 gatgaaaacc aaattactaa ttcatactat actcatttcg gttctgttgc aaagttttcc
    11941 aaaaaatcta ttttagtgta aaattgagaa aaaagacaga gagggcagag taatgaatca
    12001 ttttaaaggc aaacaattca aaaaagacgt cattattgtc gctgttggtt actacctgcg
    12061 ttacaatcta agctatcgtg aagttcagga att
//
LOCUS       DAXLPQ010000068        11637 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.070, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000068 DAXLPQ010000000
VERSION     DAXLPQ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.070"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            162..962
                     /locus_tag="ACF3UO_002368"
     CDS             162..962
                     /locus_tag="ACF3UO_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFD3658318.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKVSGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTQNLGMIKEK
                     DEEEMLWKVDGIEYVLDKAEHLVKNAKESLLIQVWHENLTDSLLKTLQQAEKRVDKFV
                     LILFSSSHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESSEELKAKYGEDFEGIRKIY"
     gene            978..1856
                     /locus_tag="ACF3UO_002369"
     CDS             978..1856
                     /locus_tag="ACF3UO_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFD3658319.1"
                     /translation="MIRNILLALIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFITFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGVKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAAFLIFMGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFDEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYVLKWIVILVLLYS
                     AYTMLGSQLKKVSAAN"
     gene            1869..2849
                     /locus_tag="ACF3UO_002370"
     CDS             1869..2849
                     /locus_tag="ACF3UO_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFD3658320.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENLKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFDRASRFAEEMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVNKAKENNLGKLIY"
     gene            3371..3589
                     /locus_tag="ACF3UO_002371"
     CDS             3371..3589
                     /locus_tag="ACF3UO_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658321.1"
                     /translation="MNFFQNVFTDFVGDFKYLIMLAMLGGAAYIAFERKASKAIPLIL
                     VLAVAVWLVGDTSGVFNWILDRMRSWGR"
     gene            3591..3998
                     /locus_tag="ACF3UO_002372"
     CDS             3591..3998
                     /locus_tag="ACF3UO_002372"
                     /inference="COORDINATES: protein motif:HMM:NF024062.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFD3658322.1"
                     /translation="MSEIRNWTKIWYIERVFYKLWDGVALPRPVTQTFAIWFGIGFFG
                     GIFRIFPFVMEHTITRQFFCPWLFAFLMTRKQFQGRKPYNYLASFLLFQCRSKESFHG
                     QWVKPIEKKEIKRGIRCVVRYGGEKDATTKTSA"
     gene            3973..6510
                     /locus_tag="ACF3UO_002373"
     CDS             3973..6510
                     /locus_tag="ACF3UO_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3658323.1"
                     /translation="MRLPKLVPKIPFYYLEDNLVFGEEDRVYAYYEFPMYSYSFVGED
                     QAYQLQQAIMRLIRQSHSSHVRFFFCTNEEKIEKTIKSSKELVRSKGELKTIAYQHLE
                     GVQHILEELHGKYIQNVCWYVGIELVLEEIAPKEAHWLKEFRIAAKDFFHRSNARLFG
                     DFETIPNEKIQRYKRLENLLYNRISKYFRLRKTTPEDMVFLVEHLEGKKEQSLDEVMY
                     RPNSFKEETNTYTYHYDVLNLASAGITEKKNYLILEQGTEKEYITYLSLSRMTRDLVF
                     PFQSEIYYFLQSELDFPIDSWLDVNLLDNRLALAKVRGKKSDLSDIYESGMSVGKDVG
                     NNVREAYQSANELEQKLEDTREDLYVLSLNVRVSGKTYDEMLKRVSDVRNFFDVYSMY
                     LEVPCNVQLLLHFGSYPAGRRVIEDYRQYVGAEFIASLGIGATQQLGDGCGIPIGFNA
                     ETGIPVFIKPWLAAQGIKGTVTNTLAKALIGSLGGGKSLTENLLLFWSVLFGALAFCI
                     DPKSERSNWSEDLPYFAPYLKTVNITSEKENIGLLDPFQLMRRKKDQESLALDVLTYI
                     TGVSIRDEDRFPLLQRAVKTVSDFEGTKGLLLVIQELYAQEAATAQRLAKHIESFKEL
                     SIAGLLFGDGTNQQGLNLDAKCNLALVQDLTLPDSETVPEDYNSSEILSIAIMMSLAT
                     YALDFIKQNRKIYKAVGLDESWAWLNVAQGKILGDKLVREGRSRNAGIDFSTQNTDDL
                     GDEKMRSKIGLKFIFRSNDREEITKALSFCGISVTEENIQRVKNLENGECLFCDIHGN
                     IGILYVYYWFEDLFHAFDTRPPMEETYEEEEYKDEILEKLVEEIEVN"
     gene            6511..8532
                     /locus_tag="ACF3UO_002374"
     CDS             6511..8532
                     /locus_tag="ACF3UO_002374"
                     /inference="COORDINATES: protein motif:HMM:NF046089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFD3658324.1"
                     /translation="MKQWYSKVSFLITRRKLVFISLVIMMGVFFFHPSLVEAAGWIKE
                     TLGGKNAVYDFETYPLDNYNLDFFVDTSWNWLPWKWGEGISNTVIYGIFAVTNILWML
                     NVYLCYFLGFLVQEAFELDFLSELIGSLSHTIQNIAGMNRTGTLSHGLVPFFGGLLIT
                     LAGCSVVYQGIVKQHPTQAIQQAVTFLFTFICCGVFFMNTNTYLEKANGVQKEINSEM
                     LTIAKNLLPEQKEKPDAIKAIRENLFAIQIKQPWLVMQFGDSDIKTVGEERIINLLKE
                     SPYDEGEQRNKLVEEEVTKQKNGHLSVQKVYLRFGMVFLTLIVNIVISMSVLVLIVIL
                     IASQVLFLLFIGFLPVAMIFSLFPNSGSLLGNALQKVFQLLFTKMGILLILTITFSIS
                     HELNHLSKDKGMIWTSFLQVTLWLSVSTRVNELLGWMKIGGVQTRAGDRTGRFLRGMM
                     LGTMGQKMIRGIGENFVGGTAGGVAGQMISKSMSGQRSIASTPLIERVGKKVSAMTEL
                     PATIESRAEQWKRTIQYVPTNAQYKAQKMKYDYFSGRMNESERQTRARNLANERQKNF
                     YEARKDALQLEQQERKQRAMRSMAHQTGKTQVTSGKLQTRKSAMIGRTEQFPTIEKRS
                     NISNIAKNKKLSKQEHPIHERSTNRKIETPVRWTSTSRQNARKGRTKKE"
     gene            8679..9467
                     /locus_tag="ACF3UO_002375"
     CDS             8679..9467
                     /locus_tag="ACF3UO_002375"
                     /inference="COORDINATES: protein motif:HMM:NF024056.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3658325.1"
                     /translation="MVFSVCFGVYNNLTSQDTHTIHETKVIDKQLKDMTGIESYVKNF
                     AFLYFTVSLESDQQINRSKAVESYLADGLQMDNEIDKDIETNVKVKNVSIWAIEEHES
                     KKHTFVVMFHVLLEIEKEFKERVYKVEVYRNELSYAIVKLPIVASNVKKATIKVDTRF
                     ETTSISRKEQEELEKFLYTFFRIYPKANAEELKYYGTTLLPIQQPLAFEELSNLQVAK
                     KEGRYEIHCNILYQDQETHLWFTMYYEMSMKQLENGNFRIEAIH"
     gene            9539..10558
                     /locus_tag="ACF3UO_002376"
     CDS             9539..10558
                     /locus_tag="ACF3UO_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3658326.1"
                     /translation="MSSGESKHMDSAVGVTHTGEYIETLPIFSEIKGRGPITDEHAQA
                     AVGAAVKYQLLPSVILSQLGYESAYGQSQSGRNDTNFFGITWFPGCPYPQGSARGIGG
                     SEGGFYMKFPNLNACYDYYGFMVASQSNFNQCVGNKDPGSCLLILGRGGYAAAGITEG
                     SSYYQGAISIIKSYNLTEYDAFAIKHWNSLPIKKTSLIAGKSKGNAKVLDRIIGRPVN
                     NGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGEDYNWATYGWQVIMNPKPSDLQAGDV
                     VNWQAGGALSPGIYGHTGIITDVSNSGQSFSTVEQNAEQGRIMARYQRGYNQAKIRSL
                     VRKVK"
     gene            10609..11121
                     /locus_tag="ACF3UO_002377"
     CDS             10609..11121
                     /locus_tag="ACF3UO_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFD3658327.1"
                     /translation="MKKYYFFFLSCFCLFGLTSCGWIFSEEKTEVSLISKEKMIQAES
                     SSKESKRNQEDKTECNISEEIQYLLKNFGRKWVNYTDIYERNQSVKNYLTDRCIKENG
                     IDNDPHIQYKTIGRIHTITQDVIQSDQYLLFGEETTNEITRFVLLQIKVDQEVQKIDK
                     IKIYYVRSAY"
     gene            complement(11240..>11637)
                     /locus_tag="ACF3UO_002378"
     CDS             complement(11240..>11637)
                     /locus_tag="ACF3UO_002378"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3658328.1"
                     /translation="TPVTPETPDPETPVTPETPDPETPVTPETPDPETPVTPETPDPE
                     TPVTPETPDPETPVTPENPEPDKPVSLKNTNSKILISEKNVSNTNSKSNNTLPQTGEK
                     ESSGVLAGLVILLASIAVGIKLNLKRKNI"
BASE COUNT         3867 a         1754 c         2500 g         3516 t
ORIGIN      
        1 tcttcacaaa cattcatata ataatagttt tatttaataa atacattgtt tttaaactaa
       61 tttctatatg tgttttgttg aactaactct tgacataaaa tttaaaagga tttatagttg
      121 ttaccgtagt agctactaaa agataaagtg aggattaatc aatggaaacg attattcaaa
      181 tcatgaaaaa atatgatttt tcagagatgg aaacaagagt gtataccaca ctattggaaa
      241 aaggcaatct tacaggatat gaagtaagta aagtctcagg tgtgccacgc tcgaaagtat
      301 ataacatttt ggaaaaacta ttaaaaaaga atttgattgt cgtcaataaa tcagaaccta
      361 aactttatca tgccatctcg gcaaatgagt ttttagagaa attagaaaaa agtgttaaaa
      421 atgatctctc ttttcttact caaaatctag ggatgatcaa agaaaaagat gaagaagaaa
      481 tgctgtggaa agttgatggc atcgagtatg ttctggataa agcagagcat ttggtgaaaa
      541 atgcaaaaga aagtttgctc atccaagttt ggcatgagaa cctcacggat tcactgctaa
      601 agacattgca gcaggctgaa aaaagagtcg ataaatttgt actgatttta ttcagttcta
      661 gccatgaata tgatcttccc ttagaaaagt attacattca tggttttgaa acagacaaac
      721 tcgctgactt tggggcaaga tggataaaca tcgtcgccga tgagcaagaa gtcgtgtttg
      781 gcaccattaa cgaagaactg caatcaaccg atgtcacttg gacaaaaaac cacgccatgg
      841 tcaatctagc aaaagaatat gtcaaacatg atgcatatac actaaaagtg attgcagaat
      901 cttctgaaga acttaaagca aaatatggtg aggactttga gggaatcaga aagatttact
      961 agtaggagga aatttttatg attcggaata ttttgctggc actaattgtc gcaatcaatc
     1021 tatattttat tatttacttt ctaagagacc ttttcaaaaa caaacaaaat ttcaaagaag
     1081 aaccagggga tatgcgtctg ttgcccttca cgtcatttat caccttcttt ctttcaacat
     1141 ttggcgtttc cgactttgct atcggaaccg tcctttatcc aaagttgaaa tgggtcagca
     1201 tgaaaaaact acccggaacg ttgaataccc aatgtgtcgt accggtagcc gtcatggcat
     1261 tgtcttatat cactgccatc aacgtagggg tcaagacact agctgtttgt attatctgcc
     1321 aaattatcgg tgcatattta ggaccaagat ttgtcgtgaa attaccagaa aaaacgatca
     1381 aactatttgt cggcatagga ttggtcattg ctgcattctt aatttttatg ggacaaatga
     1441 attggattcc ctcaaacgga acagccagtg aattgtatgg cggaaaatta atcttggcag
     1501 gatttttact ctttgtctat ggcgcattga acaatattgg cattggttct tatgcgctaa
     1561 cgatggtaac tgtctacttg ctaggcttga atccagttgc agcctttcct attatgatgg
     1621 gggcttgtac attctcagta ccgatcggca gtgtccaatt cattaaattt gatgaataca
     1681 gcagaaaaat cacacttttc acttcaacct tcggtgtatt aggggtattg gtcgctgtat
     1741 tcctagtcaa atctttagat acctatgtct tgaaatggat cgtaattttg gtcttactat
     1801 acagtgcata cacaatgttg ggcagtcaat taaaaaaagt ttcagcagct aattaaggag
     1861 cgattcaaat gttatttctt aaaaaagaag atattatcaa aagtttctca atgagagaag
     1921 ccatcgatgc agacaaaaaa gcattgtcat tgtattcagc aggaaaggca agtgtgcctc
     1981 ttcgcaccaa tatcgatgtg ccaaaaagca acggacaaag cttatatatg ccagcttatg
     2041 tagaaggtgg cgaaggtgcg ttaggtgtca aaatcgtttc cgtgtatcct gaaaacctca
     2101 agaaaaactt accaagtgta ccagccacga tgatcgtcct tgatccagaa acgggtatgg
     2161 tatccgcttg tttggatggt acctatttga cacaattaag aaccggcgct gttcaaggtg
     2221 cagcaacaga acttcttgca agagaagatg ctaaaatcgg cgcactgatc ggaaccggcg
     2281 gacaagcaca gtcgcaatta gaagcgatgt tgaccgttcg taaattagaa gaagttcgga
     2341 tttttgatat tgattttgac cgtgccagcc gatttgctga agaaatgatg caacagtttt
     2401 ctgtaacgat gcgcccaaca aaaaccagtc aagaatgcgt tgaaggagca gatatcatta
     2461 caagtgtgac cacttcaaaa cgtgcgacat tctctgctga gtgggtcaaa aaaggtgcgc
     2521 acatcaacgg agtcggtgct tacacaccgg aaatgtgtga aattccacga gaaataatca
     2581 aagccgcaga tgttgttatt tttgatacca tggacggtgt tctaaaagaa gctggggact
     2641 tcatttcacc gctgcaagat gggtatattc aaagagacag ttatcatggg gaactaggcc
     2701 aactgatcaa tgaagaattg atcggtcgga caagtggaga acaaatcaca attttcaaaa
     2761 cagttggttc ggctgtatta gatgtggtag ttgcgacaga aatcgttaat aaagctaaag
     2821 aaaataattt gggaaaattg atttattaaa taaaaagacc ggaagtaaac ctttaattag
     2881 tacatttata aaaagagaac aaaaaagact gtaatcaaaa tgcgattaca gctttttttt
     2941 gttttatttg ggaggagata gatcgtgttt atgactgtat cggatcattt aaaggtactt
     3001 ggttttatcc ctttatctag tagagggaag tatcaattgt atttgttaga tttaccaccc
     3061 tagcttttca ctgatgattg aaggaacata cgataaaaaa agtggtaagt atttttatga
     3121 tttttattct atgaaacttg atcctaaaac aaagaaaagt acgcagcacc ggatttattg
     3181 tacgcatgtt cctgtaaaag taatgtatcg tcgtgtgaga aattatttat acttcttacg
     3241 taaaaaacag caatcaagga acagaaaaaa tgcataatga ggaatatcaa gtgaaatttt
     3301 tatcagtttt gctctgtggt attgtgtatt gtcattagtt caatgagtat taacagggag
     3361 gaaaaagcaa atgaattttt ttcaaaatgt gtttaccgat tttgttgggg attttaagta
     3421 tttgattatg ttggcgatgc ttggtggtgc ggcatatatt gcctttgaac ggaaagcaag
     3481 caaagccatt ccattgattc ttgtgctagc agtagctgtt tggttagttg gagatacgtc
     3541 tggcgtattc aattggattt tggatcgtat gcggtcatgg gggcgataaa atgagtgaaa
     3601 tacgcaattg gacaaagatt tggtatatag agcgagtgtt ttataaattg tgggatgggg
     3661 tcgcgttacc tcgtcctgta acacaaacat ttgcgatatg gtttgggatt ggcttttttg
     3721 gggggatttt tcgaattttt ccatttgtta tggaacatac gattactcga caattttttt
     3781 gtccgtggtt atttgctttt ttaatgacac gaaaacaatt tcaaggaagg aagccttata
     3841 attatttggc ttcttttctt ttatttcagt gtcgttcaaa agaatccttt catggccaat
     3901 gggtaaagcc aatagaaaaa aaagaaatca aacgaggaat tcgttgtgta gtacgttatg
     3961 gaggtgaaaa ggatgcgact accaaaacta gtgcctaaga ttccttttta ttatttagaa
     4021 gacaatttag tttttggaga agaagatcgt gtgtacgctt attatgaatt cccaatgtat
     4081 tcatatagct tcgtgggaga agatcaggcg tatcaactcc aacaagcaat catgcgtctg
     4141 attcgtcaaa gtcattcttc gcatgttcgg ttcttttttt gtacaaacga agaaaaaatt
     4201 gaaaaaacga ttaaatcctc aaaagaattg gtgcgttcta aaggggaatt aaaaacgatt
     4261 gcctaccaac atttagaagg tgttcagcac attttagaag agctacatgg aaaatatatt
     4321 caaaatgttt gctggtatgt tgggattgag ctggtattag aagaaattgc tcccaaagaa
     4381 gctcattggt taaaagaatt tcgtattgcc gcaaaagatt tttttcaccg atccaatgcc
     4441 cgtttgtttg gagactttga aaccatccca aatgaaaaaa ttcaacgata taagcgattg
     4501 gagaatttat tgtataaccg gattagtaaa tactttcggt tacgaaaaac aacaccagaa
     4561 gacatggtgt ttttagtgga acatttagaa ggaaaaaaag aacaatcctt agatgaagtg
     4621 atgtatcgac caaatagctt taaagaagaa acgaatacgt atacgtatca ctatgatgta
     4681 ttgaatttgg ccagtgcagg aatcacagaa aagaaaaatt atctaatttt agaacaaggg
     4741 acagaaaaag aatatatcac gtatttatct ctttcacgta tgacccgtga tttggtattt
     4801 ccatttcaat cagagattta ttatttttta caatcggaat tggattttcc aatcgattct
     4861 tggttagatg tgaatctttt agataatcgt ttggccttgg cgaaagtacg tggcaaaaag
     4921 agtgatttat ctgatattta tgaaagtggt atgtcggttg gaaaagatgt aggaaacaat
     4981 gtacgcgaag cttaccaatc agccaatgag ttggaacaaa aattagaaga tacgcgagaa
     5041 gatttgtatg tattatcact aaacgttcgc gtgtcaggga agacctatga tgaaatgtta
     5101 aaacgtgtga gtgatgttcg caattttttt gatgtctatt ctatgtattt agaagtaccg
     5161 tgcaatgtac agctgctttt acattttgga agttatccag caggaaggcg agtgattgag
     5221 gattatcgtc aatatgtagg cgcagaattt attgctagtc ttggcattgg tgcgacacaa
     5281 caactaggag atggctgtgg tattccgatt ggatttaatg cagaaacagg aatcccagtg
     5341 tttattaaac catggttagc ggcacaagga ataaaaggaa cggttaccaa tactcttgcc
     5401 aaagcattaa ttggttcgct aggtggtggg aaatcattaa ctgagaatct cttgttattt
     5461 tggtcggtgt tgtttggcgc cttggctttt tgtatcgatc caaaatcgga acgttcaaat
     5521 tggtccgaag atttgccata ttttgccccc tacttaaaaa cagttaatat taccagtgag
     5581 aaagaaaata ttggtttact tgatccattt caattgatga gaagaaaaaa agatcaagaa
     5641 agtttagcat tggatgtgct cacctatatc acgggtgtaa gtattcggga cgaagaccgg
     5701 tttcctttgt tacaacgggc agttaaaact gtttctgatt ttgagggaac aaaaggatta
     5761 cttctagtaa ttcaggaatt atatgcacaa gaagcagcga ccgcacaacg cctggcaaag
     5821 catattgaaa gcttcaaaga actatctatt gcaggcctat tatttggaga tggcacgaac
     5881 caacaagggt taaatttgga tgccaaatgt aatctcgcac tggttcagga tttaacgtta
     5941 ccagatagtg aaactgtacc tgaggactat aactcttctg aaattttaag tattgcgatt
     6001 atgatgagtt tggctacgta tgcgctagat tttattaaac aaaatcgaaa aatttataaa
     6061 gcggttggct tagatgaaag ttgggcgtgg ttgaatgttg cgcaaggaaa aattttagga
     6121 gataaattgg ttcgtgaagg aagatctcgc aatgcaggga ttgatttttc aacacaaaac
     6181 acagatgatt taggtgatga aaagatgaga agtaaaattg ggttgaaatt catttttcgt
     6241 tcgaatgatc gcgaagaaat taccaaagca ttaagctttt gtggaatatc tgtcacagaa
     6301 gaaaatatcc agcgtgtaaa aaatctagaa aacggtgaat gtctgttttg tgacatccat
     6361 ggtaatattg gcattttgta tgtgtattat tggtttgaag atttattcca tgcatttgat
     6421 acacgaccgc caatggaaga aacctacgaa gaggaagaat ataaagacga gatattagaa
     6481 aaactggttg aagaaattga ggtgaattag atgaaacagt ggtattcaaa ggtttcattt
     6541 ttaattactc gccggaaact ggttttcata agtctagtca taatgatggg tgtttttttc
     6601 tttcacccat cattagtaga agcagctggt tggataaaag aaaccctagg cggcaaaaat
     6661 gccgtatatg attttgaaac atatccttta gataattata atttagattt ttttgtggat
     6721 acgtcgtgga attggttgcc gtggaaatgg ggtgaaggaa tttctaatac agttatttat
     6781 gggatatttg ccgttaccaa tattttatgg atgttaaatg tctacctgtg ttacttttta
     6841 gggtttcttg tccaagaagc ctttgaatta gattttcttt cagagttgat tggttcgtta
     6901 agtcatacaa ttcagaatat tgctggaatg aaccgtacag ggacattgag tcatggatta
     6961 gtccctttct ttggtggatt gttaattact ttagcaggtt gttcagtagt ttatcaagga
     7021 atagtgaaac aacaccctac gcaagctatt caacaagcgg tgacattttt gtttactttt
     7081 atttgttgcg gcgttttctt tatgaataca aacacatatt tagagaaagc taatggggta
     7141 caaaaagaaa tcaatagtga aatgttaacc attgccaaaa atctgttacc tgaacaaaaa
     7201 gaaaaaccag atgcaattaa ggccattcgt gagaatttat ttgccattca aattaagcaa
     7261 ccctggctag tgatgcaatt tggggatagt gatataaaaa cggttggtga agaacgtata
     7321 atcaatttat taaaagaatc accttatgat gaaggagaac agcgaaataa gcttgttgaa
     7381 gaagaagtaa ccaaacaaaa aaatggccat ctttcggtac aaaaagtgta tttgcgtttt
     7441 ggtatggtat ttttaacgct catcgtcaac attgtcatta gtatgagtgt tttggtatta
     7501 atcgttatct taattgcgtc gcaagtatta ttcttgttat ttataggatt cttacctgta
     7561 gcgatgattt tctcgttatt tccaaattca ggatcgttat taggtaatgc cttacagaaa
     7621 gtctttcaat tattgtttac aaaaatgggt attttactca ttttaaccat tactttttct
     7681 attagtcatg agttaaacca cttatccaag gacaaaggaa tgatttggac cagtttctta
     7741 caggtgacgt tatggttatc tgtctcgaca cgtgtcaatg aattattagg ttggatgaaa
     7801 attggtggcg tacaaacacg agctggggat cgaactggac gtttcttacg tggcatgatg
     7861 ttaggtacaa tgggtcaaaa aatgatacga ggaattggtg aaaattttgt tgggggtact
     7921 gccggaggtg tagctggcca aatgatttcc aaatctatga gtggtcaacg aagtatagct
     7981 tctacacctc ttatagagcg agtaggaaaa aaagtttcag ctatgacaga attaccggca
     8041 acgattgaaa gtagggcaga acaatggaag cggacaattc agtatgtccc aaccaatgcc
     8101 caatacaaag cacaaaaaat gaaatacgat tatttctctg ggcgaatgaa tgagtcggaa
     8161 cgacaaacac gagcgcgtaa ccttgcgaat gagcgacaga agaattttta tgaagcacga
     8221 aaagatgcat tgcaattaga gcaacaagag agaaaacaac gagcgatgcg ttcaatggcg
     8281 catcaaacag gaaaaacaca agtgacttct ggtaaattac aaacacggaa aagtgcaatg
     8341 attggtcgaa cagaacaatt tcctacgata gaaaaaagaa gtaacatttc aaatatagct
     8401 aaaaataaga aattgtcgaa gcaggaacat ccgattcatg aacgaagtac gaatcgaaag
     8461 attgaaactc cggttcgttg gacttcgact tctcgtcaaa acgcgagaaa aggtagaact
     8521 aaaaaagaat aaggaggagg gctatgtttc ctcggaagaa aaaactgtct attctctctg
     8581 aacaagaaac aagactaaaa ggaaagaaag acaagaaaaa agaaagctat aagggagcgc
     8641 gaaaaaggcg cttccttttt tttgtaggct ggagcttttt ggtttttagt gtttgttttg
     8701 gagtttataa taatttaact tctcaagata cgcatacaat ccatgaaaca aaagtcattg
     8761 ataaacaatt aaaagatatg actggaatag aaagttatgt gaaaaatttt gcatttttgt
     8821 attttacagt gagtcttgaa agcgaccaac aaataaatcg atcaaaagca gtagaaagtt
     8881 atttagctga tgggctgcaa atggataatg aaatagataa agacatagaa acgaatgtaa
     8941 aagttaaaaa tgtctcgatt tgggcaatag aggaacatga atcaaaaaaa catacatttg
     9001 tggttatgtt tcatgtctta ttagagatag aaaaagaatt caaagagcgt gtgtataagg
     9061 tggaggtata tcgaaacgaa ttatcatatg ccatagtgaa attgcctatt gtagcgagta
     9121 atgttaaaaa agcaacgatt aaagtagaca ctcggttcga aacaacgagc atttctcgaa
     9181 aagaacagga agaattagag aaattcttat ataccttctt tcgtatttat cctaaagcaa
     9241 acgcagaaga attaaaatat tatgggacaa ctcttttacc aattcaacag cctttagcct
     9301 ttgaagaact atcgaatttg caagtcgcaa aaaaagaggg tagatatgag attcattgta
     9361 atattttgta tcaagatcaa gaaacgcacc tttggtttac catgtactat gaaatgtcta
     9421 tgaaacaatt agagaatggg aactttcgaa ttgaggcgat tcattagtga aaaagatttt
     9481 tttatttagt ggcatctgta tgatgagttg tctgttttta ttatttgcga taattagcat
     9541 gtctagtggt gaatcgaagc acatggattc agcagttggt gttactcata cgggagaata
     9601 tatcgaaacc ttacctattt tttcagagat caaagggcgt ggtccgataa cagatgaaca
     9661 tgcccaagca gcagttggtg cagctgtaaa gtatcagtta ttaccgagtg tgattctttc
     9721 tcaattagga tatgaatcag cttatgggca gtcacaatct ggaagaaacg atacgaactt
     9781 ttttgggatt acgtggtttc ctggttgtcc ctatccacaa ggttctgcac gtgggattgg
     9841 tggttctgaa ggtggtttct atatgaagtt tccgaacctg aatgcttgtt atgactatta
     9901 tggatttatg gtggcgagtc aaagcaactt taatcaatgt gtgggcaata aagatcctgg
     9961 aagttgttta ttgattctag gtcgtggagg ttatgcggcg gcaggtatca ccgaaggcag
    10021 ttcgtattat caaggcgcaa taagtatcat aaagtcctat aacttaacgg aatatgatgc
    10081 ctttgcgatc aagcattgga atagcctacc aatcaaaaaa acttcgctta ttgcaggaaa
    10141 aagtaaaggc aatgcgaagg ttttggatcg gatcattgga cgacccgtaa ataatgggga
    10201 atgttatggt ggtacggcat ggtatgtatc tcaactaggt ggcccacagt taatgggttc
    10261 tggacacatg tttgcgatgt taatagggga agattataac tgggcaacct atggttggca
    10321 agtgatcatg aatccaaagc ccagtgactt acaagcagga gatgtggtca attggcaagc
    10381 aggtggtgca ttgtctcctg gaatctatgg ccacacgggt atcataacag atgtctcaaa
    10441 tagtggacaa agtttctcca ccgtagaaca gaacgccgag caggggcgaa ttatggcacg
    10501 gtatcaacgc ggctataacc aagcgaaaat tcgaagtctg gttcggaaag tgaaataaaa
    10561 gaattctttc gatgaaaatt tttagtagaa aagggagaag gatcgattgt gaaaaagtat
    10621 tattttttct ttctaagttg tttttgtttg tttggactta ctagttgtgg gtggattttt
    10681 tctgaagaaa aaacagaagt ttccttaata tcaaaagaaa agatgataca agcagaaagt
    10741 tcaagtaaag aaagcaaaag aaatcaggaa gacaaaacag aatgcaatat ttctgaagaa
    10801 atccaatatt tgttaaagaa ttttggaaga aaatgggtga attacacgga tatatacgaa
    10861 cgaaatcaat ctgtaaaaaa ctatttaacc gatcgttgta taaaagaaaa tgggattgac
    10921 aacgatccac atatacaata taaaacaatt ggccgtattc atactatcac acaagatgta
    10981 atccaatcgg atcaatattt attatttgga gaagaaacaa caaatgagat aactcggttt
    11041 gtgttacttc aaatcaaggt ggatcaagaa gtgcagaaga ttgataaaat caagatttat
    11101 tatgtaagaa gtgcatatta aaataaaaaa ggaattgtgg aaattgtttg taattaaatc
    11161 gaacagtgat tatttatttt aaattgaaaa cagagatagg atgaatactt attctatctc
    11221 tgttttcttt tggactaatc tagatatttt ttcgttttaa atttaattta atacccactg
    11281 caatagaagc taataaaata actaatccag ctaaaactcc tgatgattct ttttcaccag
    11341 tttggggaag agtattattt gactttgaat tagtatttga aacattcttc tctgatatta
    11401 aaattttaga gttagtgttt tttaaagaca ctggtttatc aggctcaggg ttctcaggcg
    11461 ttactggagt ttccggatct ggagtctcag gtgttaccgg agtttctgga tctggagtct
    11521 caggtgttac cggagtttct ggatctggag tctcaggtgt taccggagtt tctggatctg
    11581 gagtctcagg tgttaccgga gtttctggat ctggagtctc aggcgttacc ggagttt
//
LOCUS       DAXLPQ010000069        11253 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.071, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000069 DAXLPQ010000000
VERSION     DAXLPQ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.071"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(1..459)
                     /locus_tag="ACF3UO_002379"
                     /pseudo
     CDS             complement(1..459)
                     /locus_tag="ACF3UO_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
     gene            complement(711..1070)
                     /gene="rplT"
                     /locus_tag="ACF3UO_002380"
     CDS             complement(711..1070)
                     /gene="rplT"
                     /locus_tag="ACF3UO_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFD3658329.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1123..1323)
                     /gene="rpmI"
                     /locus_tag="ACF3UO_002381"
     CDS             complement(1123..1323)
                     /gene="rpmI"
                     /locus_tag="ACF3UO_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFD3658330.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1395..1919)
                     /gene="infC"
                     /locus_tag="ACF3UO_002382"
     CDS             complement(1395..1919)
                     /gene="infC"
                     /locus_tag="ACF3UO_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFD3658331.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1963..2088)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2239..2871
                     /locus_tag="ACF3UO_002383"
     CDS             2239..2871
                     /locus_tag="ACF3UO_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFD3658332.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2873..3778)
                     /locus_tag="ACF3UO_002384"
     CDS             complement(2873..3778)
                     /locus_tag="ACF3UO_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3658333.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3863..4522)
                     /locus_tag="ACF3UO_002385"
     CDS             complement(3863..4522)
                     /locus_tag="ACF3UO_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3658334.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4838..5782
                     /gene="mvk"
                     /locus_tag="ACF3UO_002386"
     CDS             4838..5782
                     /gene="mvk"
                     /locus_tag="ACF3UO_002386"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFD3658335.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5775..6752
                     /gene="mvaD"
                     /locus_tag="ACF3UO_002387"
     CDS             5775..6752
                     /gene="mvaD"
                     /locus_tag="ACF3UO_002387"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFD3658336.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6765..7850
                     /locus_tag="ACF3UO_002388"
     CDS             6765..7850
                     /locus_tag="ACF3UO_002388"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFD3658337.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7847..8911
                     /gene="fni"
                     /locus_tag="ACF3UO_002389"
     CDS             7847..8911
                     /gene="fni"
                     /locus_tag="ACF3UO_002389"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFD3658338.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9160..9963)
                     /locus_tag="ACF3UO_002390"
     CDS             complement(9160..9963)
                     /locus_tag="ACF3UO_002390"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFD3658339.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9983..10306)
                     /locus_tag="ACF3UO_002391"
                     /pseudo
     CDS             complement(9983..10306)
                     /locus_tag="ACF3UO_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
     gene            complement(10339..10476)
                     /locus_tag="ACF3UO_002392"
                     /pseudo
     CDS             complement(10339..10476)
                     /locus_tag="ACF3UO_002392"
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
     gene            complement(10520..>11253)
                     /locus_tag="ACF3UO_002393"
     CDS             complement(10520..>11253)
                     /locus_tag="ACF3UO_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFD3658340.1"
                     /translation="DKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRK
                     LMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKI
                     YLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQ
                     YQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIR
                     WYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT         3315 a         2347 c         2107 g         3484 t
ORIGIN      
        1 atacctaatg acatcaagat cggcaacaca ataactgcaa tagaaatcac tggtccgatt
       61 cctgtcatcg acatgaatat aacagcggtt acaatacata gtaagctcat cgtgattctt
      121 ggcttgtccc ctccaagttc aactaccttt cgaatcaggg tagctgcgat tccgctatct
      181 actagaacac gcccgaaaaa ggcaccaaag aagacattta ccaagatcga tttggcgtac
      241 tcagctggcc ccgtcgtata gatatgcgtc aacacatcaa ttactccttg cccttccatc
      301 gccgagtttg gtgaaaacgt gtttccgact agcgctaatc ccatccatac agtagccatg
      361 atgacaaaag ccgaccatca agttgtagcc ttttacacag taccagacca tgaaaaagaa
      421 tgagataact aacaaaatac caataataat atcactcatg ttattcctcc gtccattttg
      481 tttttctgat aagcaaacta atatatcagt caaactcatt ctaacttatg tagttagcgc
      541 tttcattaaa ggatgaccat aaatgttcag ttttcaatta aaaaacctta attatgttat
      601 tttagactta tacgttattg tcctgtttca tttgatggag gattgtaaat aaaaaaagag
      661 gaaagaacat aacttttcgt tatcttcttt cctctttata attgtttagc ttatttagcc
      721 aaagcttctt ttgcttggtc agccaatgca gtaaatgctg ctgcatcgtt aacagccaag
      781 tcagctaaca ttttacggtt gatgtcgatt tcagcaactt tcaaaccgtg cattaatttt
      841 gagtagctca agccattcat acgagctgct gcgttgatac gagcaatcca caatttacgg
      901 aagtcgcgtt tcttttgacg acgatcgcga tatgcgtagt tgtatgaatt cattacttgt
      961 tcttttgctg ttttaaataa agtgtgtttt gaaccgtagt aaccttttgc taattttagc
     1021 actcttttac gacgtttacg agttactgtt ccacctttaa cacgtgccat gtataattcc
     1081 tcctaataaa aataaatctt cagattctgt tatttgtact tcttatttca tttttgctag
     1141 ttgttggcga atacgtttga agtcgccact agaaaccatg cttgctttac gcaattgacg
     1201 gcgttgtttt tttgttttgc cgtggaaacg gtgacttgta aacgcgcgga agcgtttcaa
     1261 tccgccttta ccagtacgtt tgaaacgttt tgctgatccg cggtgtgttt tttgttttgg
     1321 catgactata tttcctcctc aaaatctttc gttatccgac tatcggctgt ccaacagcca
     1381 gttagtcatt caaattactt actgtcgttt ttcggtgcca gcgtcaagaa catgctgcgt
     1441 ccgtccattt tcgctttttg ttccactgtt gcaatatccg cagtttcttc agctaagcga
     1501 ttcaagactt tttgaccaat ttctttatgg gtaatggcac ggcctttgaa acggatagaa
     1561 gctttcactt tatcgccctt ttccaagaac ttacgtgcat tacgaagttt tgtattgaag
     1621 tcattcaagt cgatcgtagg acttaagcga acttctttta cattgatcac tttttgtttt
     1681 ttacgcgctt cgcggtcttt cttttgttgt tcgaaacggt atttaccgta gtccatgatt
     1741 cgcgcaactg gtggtttcgc accaggggca actaacacaa gatccaagtt tgcttgttct
     1801 gcaatattca atgcttctgc ttttgtctta actcctaatt gctcaccatc tgaaccgatc
     1861 aatcgtaact ctcgtgcacg aatgccgtcg ttaaccatca tatcctttgc tatggtcatt
     1921 cacctccaaa tattatgaga gaaagaaaag cttaccgaat aaacggcaat aaaaaaacga
     1981 gttctcttac agaacccgcg cgtacttcac ctaatagaac cagtgaaaac tatctagccc
     2041 agtgacatta tcaactaagg cgagaagcgg gtgcttctgc ttttatttct caaccattat
     2101 agtatagcaa aaactaatct ttttgtcaat gtttttcata cagtttgtct tccttttctg
     2161 aaaatgatta gattagcagg ctttctagca gtgattcccg cttctttgct atactaaaga
     2221 aaaacgaggt gaacccacat gaaaaaaatc gaacctattc caccttctct tcctcttctt
     2281 acaaagggag agttttattt agaagatgag gagatcttct ctggtcttct gatcaacgga
     2341 ggtaaccaaa gctatctcga tgccaaaaat atggtattaa gagagagtca tatccaaaaa
     2401 cttacgatgc aaaaaacagg tttacgtcat tttgaatgca gtaatgtcat ttttgaaaaa
     2461 tgtgattttt ccaatctgga gtggattggt ggcagtttcc accaagtcgt gtttcatcaa
     2521 tgtaaattaa caggtacgaa ttttgccgaa agttatcttc gagactgtac tttcactgat
     2581 tgtattgctt cgatggcttc ctttagtagt acaaacttga aagctgtctc cttcgatcat
     2641 tgtcaattag aagacagcga attttatgag gtcacttgga aaaacctttt tttgtctgac
     2701 aatcagttaa ccggttcgaa ctggtttcga acttctctga agggattaga ctttacgact
     2761 aatttcttca caacaatcgc tttatctcaa gattctttgg cgggactaat cgtcaatcaa
     2821 gagcaagcac ttgtgatcgc ccaagccctt ggtttgcaga tcaaagacta gatcaacgaa
     2881 tccgccgcca cagtgcaata agcatccaaa tagataagac caaactgatg atcaaggcga
     2941 tttcccatcc gaaaacggaa tgggtaaagg gtaactggag attcattccg aagaatcctg
     3001 tcacaatagt tggaacggtc aagatcagcg accagaccgt caaaaatttc atcgtgtcat
     3061 tcaagttgtt attcagcaaa ttattataag tgccagagag ctggtctaaa atctgcgaag
     3121 ctaagttcgt catttcaact gcttgtcgtg cttcgatcag tgcatcgtcc aactcttctt
     3181 tttccttttc tgacaacttg cgataaatag ccagtgcctt gatttgttct aaaagtacta
     3241 cattttgttt tgttcctgta actaagtaaa ccaaaccgat ctctaaatct gaaagttgca
     3301 gcagattctt gttcgttgtt ttttctctta atttcagatt aagccgctga cgttcactat
     3361 tcacttcctc gattaaagga aaaaaggaat cagaaatcaa aaacaatgta cgaaacaata
     3421 aactgtatac actcatgtct ggcatccgtt ccaaaagcga tcgaattagt cgaatcacgt
     3481 actcggtatt cggcgtggta aatgtaaaca aaccgtcttc ttttaaaata aaagcgatag
     3541 gactagtttc ataatgatta tcgacttttt gctggtgcgg aacatttgat acaagcagta
     3601 acgcttcatc aaaagaatcg tactctacgc gcgcccgttc atttttatct agagaataag
     3661 tcagcatctc gtcactaatg ccatattctt cttttaagtt tttaacagct agcacatcgt
     3721 tttgctgtac attgatccaa aaattacggt cttgattaaa atagtgtttt tcccgcatac
     3781 tctatcctcc tgacatttgt ttccagtata aagaaaaaag tcgctcaaat aaaggtttac
     3841 cctttatttg agcaactgta aatcaaatgg atactttggt ttggcgaatc tctgctaatt
     3901 tttcttcgat cattttcaag acttcttctt ttgcttgagg atcttccaca aaattatagc
     3961 ggtctccatc gatttggatt tttggacttt ctttgtattc ttcataccat tgatcataac
     4021 gtctgttcaa ttctttgtaa taatcgtata gacttgggtc aaaggacaat tgttcatacg
     4081 aacgaccacg tttttcgata cgctctaaca tcgtatcaaa agatacacga atatgaacta
     4141 ataaatccgg atgtttttta tgggcagcat agggaagttc ttccatcatg ttttccagca
     4201 gttcatcata cacacaaact tctgtttctg ttgctcttcc tagatctgca tttagatgga
     4261 aaagcagtga atcttcataa atcgaacggt ccaatacatt attgtcatct ttcattgctt
     4321 gtttgatgct tgcaaaacgt ttattcaaaa aataaatttg cagcaaaaaa gcatactgtt
     4381 cagggtttgc ataaaataag ggcaagactt cattatcatc aatcgattca taaaatgcct
     4441 gactatcaaa gtgttcagcc atcatttctg ttaaacttga ttttccggca ccaattgtac
     4501 ctgctaaaac gatcacgctc atttacctcc agctcacttc atcactaaat attgtgttta
     4561 actccaacct tttttaaata tacccccaat atctagtagt gtcaattgta ttttttctag
     4621 tcaaagaaga aaaaaagtca aaaaattctt aagaaaaaag tgttttttct ttagaaaacg
     4681 tattcttagt tttacttctg agatggtttt agtaaaataa aggaggaatg ttttttgaga
     4741 cccttagtgg acaaaaaaat tcgtgaagca gcgcaactcg ttttgggcgc tttatttttt
     4801 gcttaaaaat cacttttacg tgagaaggag ttagattatg gcaaactatg gccaaggaga
     4861 atcaagcgga aagatcatat tgatgggcga gcacgcggtt gtttatggag aaccagcgat
     4921 tgcctttcct ttctatgcaa caaaagtcac cgcattcctt gaagagctgg atgcaatgga
     4981 cgatcaactg gtttcttcct actattcagg aaatttagcc gaagctcctc atgcattaaa
     5041 aaatatcaaa aaattattca ttcacttaaa aaaacagcat gacatccaaa aaaacttgca
     5101 actgaccatt gaaagcacga ttcctgctga acgtggaatg ggatcaagcg ctgcagtcgc
     5161 cacagcagtc actcgtgctt tttatgatta cttagcattt cctttgtctc gtgaaatact
     5221 attagaaaat gtccagcttt cggaaaaaat cgcccacggt aatcctagtg gaatcgatgc
     5281 agccgctact agcagcttgc agccgattta ttttacaaaa gggcatcctt ttgactactt
     5341 ttctttgaac atcgatgctt ttttgattgt cgctgataca ggaatcaaag gacaaacaag
     5401 agaagccgtc aaagatgtcg ctcacctctt tgaaacccag cctcatgaaa ctggacaaat
     5461 gatccaaaaa ttaggatact tgacgaagca agcaaaacaa gcaatcattg agaattcacc
     5521 agaaacgttg gcacagacaa tggatgaatc acagtcactt ctggaaaagc tgacaatcag
     5581 caatgatttt cttaatctat tgatccaaac agcaaaagat accggggcat tgggtgccaa
     5641 attaactggc ggtggacgcg gtggctgtat gattgcatta gcacaaacaa aaacaaaagc
     5701 ccaagaaatc agtcaagcac ttgaagatgc gggtgctgct gaaacttgga tacaaggatt
     5761 aggagtacat acctatgttt aaaggcaaag cacgcgcata taccaacatt gctctaatca
     5821 aatattgggg taagaaaaat gaagaactca tccttccaat gaacaacagc ctttcgttaa
     5881 cattggatgc attttataca gagacagaag tcatcttttc tgatagctat atggtagatg
     5941 aattttatct agatggcacc ttacaagacg aaaaagcaac aaaaaaagtc agtcagtttc
     6001 ttgacctttt tcgtaaagaa gccggcctct cactaaaagc ttcagtaatc agtcagaatt
     6061 tcgttcctac cgcagctgga ttagcctcct ctgccagcgg gctagctgct ttagcaggag
     6121 cttgcaatac tgctcttaag cttggattag acgatctctc tctttcaaga tttgctcgac
     6181 gcgggtctgg ttcagcttgc cgaagtattt tcggtggttt cgttgaatgg gaaaaaggcc
     6241 atgacgactt aagttcttac gctaagccag tcccttccga ttctttcgaa gacgatttag
     6301 caatggtttt cgttttgatc aacgaccaga aaaaagaagt gtccagcaga aatgggatgc
     6361 gtcgaacagt cgaaacatcc agtttttatc aaggctggtt agattccgtt gaaggggatc
     6421 tatatcaatt gaaacaagca atcaaaacaa aagatttcca acttctcgga gaaacgatgg
     6481 aaagaaacgg actaaaaatg catggaacga ctttagctgc ccagcctcca ttcacttact
     6541 ggtctcctga cagcttaaaa gcgatggatg cggtgcggca attgagaaaa aaaggcattc
     6601 catgctactt tacgatggat gctggcccta atgtcaaagt tttagtggaa aacagccatt
     6661 tatctgaggt acaagaaaca tttaccaaat tatttagcaa agaacaagta attactgccc
     6721 atgctggtcc aggaattgcg attattgaat aaagggagat ttttatgatt gaagtatctg
     6781 caccaggcaa actctatatt gccggagaat atgcagttgt tgaaacagga catccagcag
     6841 ttatcgctgc agtcgatcaa ttcgtaacag tcactgtaga atccgcacga aaagtcggaa
     6901 gtatccaatc tgcacaatat agtgggatgc ctgtacgttg gacaagacgc aacggagaat
     6961 tagttttaga tattcgggaa aatccttttc attatatcct tgctgctatt cgtttgactg
     7021 aaaagtatgc acaagaaaaa aacattcttt tatcctttta tgatctgaaa gtaacaagtg
     7081 agttagacag ttcaaatggc cggaaatatg gattgggttc tagcggtgcc gtgaccgttg
     7141 caacggtcaa agccttgaat gttttttacg cgttgaattt atctcaattg gagattttca
     7201 agattgcagc actagccaat ttagcagttc aagataatgg ttcctgcggc gacatcgctg
     7261 ctagctgtta tggtggctgg atcgctttct caaccttcga ccatccttgg ctccaagaac
     7321 aagaaactca gcattctatc agtgagttac ttgccctgga ttggccaggt ctatccattg
     7381 agccattgat tgctcctgaa gatttacgtt tattgattgg ttggacgggt agccctgcct
     7441 ctacttctga tttggtcgat caagttcacc gttcgagaga agacaaaatg gtggcttatc
     7501 agcttttctt aaaaaacagt acagaatgtg tcaacgaaat gatcaaaggg tttaaagaaa
     7561 ataatgtaac gttgatccaa cagatgattc gaaaaaaccg acaattactg catgatttat
     7621 ctgcaatcac tggggtcgtc atcgaaacgc ctgctttgaa caaattgtgt aatttagctg
     7681 aacagtatga aggagccgca aaatcttctg gtgcaggtgg tggcgattgc ggaatcgtaa
     7741 ttgttgacca gaaatctggc atccttcctt taatgagtgc atgggaaaaa gcagaaatca
     7801 ctccactgcc gttacatgtc tatagcgatc aaagaaagga aaaccgatga atcgaaaaga
     7861 cgaacatgtt tcactagcta aagcctttca tgataaacaa aaaaacgaat ttgacttcgt
     7921 acggatcatc cataaccctt tgccgcaaat agcagtttct gatgtcgatc taagtacaca
     7981 ggcagttggg tttacactaa gcagcccatt ttatatcaat gcgatgactg gcggaagcga
     8041 aaaaacaaaa aaaatcaacc aagatcttgc aatcgtcgca agagaagcag atttgatgat
     8101 tgccactggt tcagtcagcg ctgccttgaa agacccttct ttagccgata cttatacgat
     8161 tatgcgacaa gaatatcctc acgggaaaat cattgccaac atcggtgcag ggacttctgt
     8221 cgaaagagcc caagaagcta tccgattgtt tcacgcagat gccttacaga ttcatttgaa
     8281 tgcacctcaa gagttggtta tgcctgaggg agaccgtgat tttaccaatt ggaaagtact
     8341 tattcaagag actcaaacag ccattgacgt ccccctcatc gtaaaagaag tcggttttgg
     8401 catgacaaga gaaacgctca atgatctagc tgctttagga gttcatacag ttgatatcag
     8461 cggtcgaagc ggaacaagct tcacccagat cgaaaacgcc cgtcgctcca agcgggaact
     8521 gagttattta gctgactggg ggcaatcgac agtctcttca ttgcttgaag caaatgaagc
     8581 agacacttct atggaaatcc tagcctccgg aggtatccgc aatgcctatg acatatttaa
     8641 agccctttgt ctcggcgcaa atgcagtggg tacttcagga accgtactga cgcatctgat
     8701 gaatcacggc gtagaagaaa ctattatact gatgaagcaa tggcaagaag agcttcgtct
     8761 gctttatact atggtcggcg caacgaatac cgcggcccta caccaacaat cactgatctt
     8821 ttccggacca gtgaaggatt ggtgcgaagc aagagggatc gacttagtga agtatggaag
     8881 acgcacagaa aagagcgtgg gacaaaagta aagaacactt ttatcccacg ctctaaacac
     8941 gtataaacgg cggaagcaaa agcaactcct tcggaaataa gctgaaattc acaaaaattt
     9001 gaaaagcaat tttcgtgaat tccttcttat ttcttggagt taaacgcttc tgtcccagcc
     9061 tcttttttcg aataaatgat gtttaatcag ctgtccttcg gtattcgttc aagccgctga
     9121 tttcacaacc tctccactaa acggtgtact aaagctcttt taaggttgtt ttccgatata
     9181 ggcaagtatg cctccgtcca catacaagac atggccgtta acgaaatcag atgcgctaga
     9241 agccaagaag acagatggtc cagccaaatc gattggctcg ccccagcgtg ctgctggcgt
     9301 acgtccaacg ataaattgat cgaatggatg acgttcaccg ttttcttgtg tttcgcgtaa
     9361 tggagcagtt tgcggtgtag caatataacc tggtccaatt ccattacatt ggatattgta
     9421 ttgaccgtat tcagaagcga tgtttttcgt cagcattttt aatccgcctt ttgccgcagc
     9481 ataagcactg accgtttcgc gtcctaattc actcatcatg gagcagatat tgatgatttt
     9541 accgccgcct ttttcgatca tatcccgaat aactgctttt gaaacgatga atggggcatt
     9601 taaatccacg tcgattactt ggcggaagtc tgccgcatcc atttcgatca tcggtgtccg
     9661 tttgatgatc cctgcattgt tgactagaat atcaactgaa cctacatctt ctttgatctg
     9721 ttgaaccatc gcttgaaccg cttcttcatc ggtcacatcg cagacataac cttttgcatc
     9781 gatgcctgct tctttataat gcgctatacc ttcatcaact gattcttgat tcaagttatt
     9841 aaatacgatt tttgctcctg ctgtagctaa agagcgtgca atctcaaatc caataccata
     9901 gacagcaccg gtgactaatg ctacttttcc atctaaacga aacatatcca tactaaattc
     9961 catcattttc tctcccttat gcttatttta attgatccat ttgcaccata tccatgtctg
    10021 tataggtgat attttctccg cacattgccc agatgaatga gtaattgctt gtacctacac
    10081 ctgaatggat cgaccagctt ggcgaaataa tggcttgttc attgtctacg actaaatgtt
    10141 ttgtttcatc tggtttgccc atcatatgga acacacgtgt atcttcattg gcataatcaa
    10201 aatagacata agcttccata cgacgttcat gtgtatgaca aggcatcgta ttccaagcac
    10261 ttcctggttc taaaatcgta taacccattt ataaatgaca gctatcgctg aagcttctac
    10321 tgctgtaaat atccccgtca agataccacc gataatgatg acaatcaata gaaggctagg
    10381 aatcgcctct tttattattt ttccagcatg agccatctgt cctttttcga caacagggta
    10441 tttattcttt ttagcaacga tgaatgctac tagcatgatt cctagcgccc acaaagtgaa
    10501 ctgaacccca aaagttgaac tatttaatgg actgtttccg atattctact ggagatagtc
    10561 catttaactt tagttttatc cttttgttat tataccacct aatatactca tttaatttac
    10621 tttgaaatat ctcaattgat cggaattttt ctcgataaaa aaactctgat ttaagcacac
    10681 caaaaaaatt ttctattaca gaattatcta agcaatttcc ttttctagac atgctttgaa
    10741 taatgttatt ctcttttaat tttttttgat attgtggcat ctgatactgc catccttgat
    10801 ctgaatgtag aatcagtgaa ccctcagttc cctttttttt aattgcttgt tgaagcattt
    10861 cttcaatcag tttatatgtt ggactagttg atatactata actaattatt tctccgttaa
    10921 ataaatcaag tataggagat agatagattt ttcttccttt tatcttgaat tcagtgacgt
    10981 ctgtcaccca ttttttattg ggtgtatcta ctgaaaaatt tcgttttaac acattcttgg
    11041 caatttttcc tactgttcct ttataagatt tatatcgctt tattcggatt tgacaggtaa
    11101 gtcccatttg ggacattaat tttctaactg ttttatgatt gattgtatat cctttcatct
    11161 ttaacgctaa agtgactcta cgataaccat aagagtttct tgattctttt acaatcgctg
    11221 taatttcttg ctttatcttg ctatatttat ctg
//
LOCUS       DAXLPQ010000070        11148 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.072, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000070 DAXLPQ010000000
VERSION     DAXLPQ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.072"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            6..305
                     /locus_tag="ACF3UO_002394"
     CDS             6..305
                     /locus_tag="ACF3UO_002394"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3658341.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACF3UO_002395"
     CDS             378..1739
                     /locus_tag="ACF3UO_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFD3658342.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACF3UO_002396"
     CDS             1761..2021
                     /locus_tag="ACF3UO_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658343.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACF3UO_002397"
     CDS             2035..2787
                     /locus_tag="ACF3UO_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFD3658344.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACF3UO_002398"
     CDS             complement(2881..3486)
                     /locus_tag="ACF3UO_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3658345.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACF3UO_002399"
     CDS             complement(3542..4516)
                     /locus_tag="ACF3UO_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFD3658346.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACF3UO_002400"
     CDS             complement(4894..5613)
                     /locus_tag="ACF3UO_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3658347.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACF3UO_002401"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACF3UO_002401"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFD3658348.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACF3UO_002402"
     CDS             7164..8561
                     /locus_tag="ACF3UO_002402"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3658349.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACF3UO_002403"
     CDS             8642..9082
                     /locus_tag="ACF3UO_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3658350.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACF3UO_002404"
     CDS             9229..9555
                     /locus_tag="ACF3UO_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3658351.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACF3UO_002405"
     CDS             9556..10305
                     /locus_tag="ACF3UO_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFD3658352.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACF3UO_002406"
     CDS             complement(10331..10741)
                     /locus_tag="ACF3UO_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3658353.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3536 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaatt
//
LOCUS       DAXLPQ010000071        10848 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.073, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000071 DAXLPQ010000000
VERSION     DAXLPQ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.073"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(137..1717)
                     /locus_tag="ACF3UO_002407"
     CDS             complement(137..1717)
                     /locus_tag="ACF3UO_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFD3658354.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2118..3494)
                     /locus_tag="ACF3UO_002408"
     CDS             complement(2118..3494)
                     /locus_tag="ACF3UO_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFD3658355.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3622..4710)
                     /locus_tag="ACF3UO_002409"
     CDS             complement(3622..4710)
                     /locus_tag="ACF3UO_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3658356.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4882..5316
                     /locus_tag="ACF3UO_002410"
     CDS             4882..5316
                     /locus_tag="ACF3UO_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658357.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5394..5927)
                     /locus_tag="ACF3UO_002411"
     CDS             complement(5394..5927)
                     /locus_tag="ACF3UO_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFD3658358.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6021..7199)
                     /gene="mutY"
                     /locus_tag="ACF3UO_002412"
     CDS             complement(6021..7199)
                     /gene="mutY"
                     /locus_tag="ACF3UO_002412"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFD3658359.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7192..7989)
                     /gene="recX"
                     /locus_tag="ACF3UO_002413"
     CDS             complement(7192..7989)
                     /gene="recX"
                     /locus_tag="ACF3UO_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFD3658360.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8096..9478
                     /gene="rlmD"
                     /locus_tag="ACF3UO_002414"
     CDS             8096..9478
                     /gene="rlmD"
                     /locus_tag="ACF3UO_002414"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD3658361.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9652..10230)
                     /locus_tag="ACF3UO_002415"
     CDS             complement(9652..10230)
                     /locus_tag="ACF3UO_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFD3658362.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10552..>10848
                     /locus_tag="ACF3UO_002416"
     CDS             10552..>10848
                     /locus_tag="ACF3UO_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFD3658363.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFN"
BASE COUNT         3232 a         2186 c         1875 g         3555 t
ORIGIN      
        1 agacatttct atgattttaa tatagtaaaa agagccgtca cggaaaatcc gtcacggctc
       61 taaacaaaat atgagaggct gtttttgttt ggctattctt attacttgat gcagggcagc
      121 ttgtgtcaag acttctttac atcaaacttt ttaattttac attgggatat ttatccgcaa
      181 accagcgttc tgcaaattgg ttctcgaata agaacaacgg ttggtcgaaa cggtcacgag
      241 ccaagatatt gcgacttgaa ctcatcttct catccaaatc ttctggatcg atccagcgag
      301 cgattttgtg tcccattgga gacatgatta cttcggcgtt atactcattt aacatacgat
      361 attggaatac ttcgaattgt agctgaccaa cagctccaat gatatattct tccgttagat
      421 atgttttata aagctgaatc gctccttctt gaactaattg atagattcct ttgtggaagg
      481 atttttgttt catgacattt tttgcagtca ctttcataaa cagctctgga gtaaatgaag
      541 ggagttcttc ataagcaact tttagttttc cttcgaacaa tgtatcccca atctgataat
      601 tgcctgtatc atatacaccg atgatatcgc ctgctactgc tttttcgacg ttttctctcg
      661 aatctgccat aaattgtgtg acattgctta atttcagttt tttatttgta cgttccaacc
      721 agacatccat tcctcgttcg aatgttccag aacagattcg gacaaaagcg attcggtcac
      781 gatgggctgg attcatattt gcttggatct tgaatacgaa acctgaaaat tcttcctcat
      841 aaggacttac catctgatca tcttgtgttt tgtgtccata aggagctggt gccaattcaa
      901 cgaaagtctc taaaaaagtc tgtacaccga agttagtcaa tgcagaacca aaaaatactg
      961 gtgtctgatc gccacgagca attttttctt gattaaatgc atctccagcc tctttgatta
     1021 gttctacttc ttctaagact tgttcatata aggaattttc agttagagga tgattttcgg
     1081 gaagcagtcc atcttcatcc aattctacta atcgttcatc ctgataattt tccggacgat
     1141 aaaactctac acgattatgg tagatatcat aaagaccttc tagcccttta cccataccga
     1201 ttggccaatt catcggataa gattcgatat ctaatagctc ttctaattct tctaacaatt
     1261 ccaatggttc acgaccatca cgatctagtt tgttgataaa agtaaatatc gggatgccac
     1321 gtttttttac aacttggaat aatttctttg tctgtgcttc gatccctttt gcactatcga
     1381 ttaccatgac cgcactatcc acggccatca aagtacgata agtatcttca gaaaaatctt
     1441 catgtcctgg tgtatccaag atatttactc gtttcccttg ataatcaaac tgcataacag
     1501 aactagtaac agaaatccca cgttgtttct cgatttccat ccagtctgat ttggcaaaat
     1561 tacctgtttt tttgcctttt acggtcccgg cttgacggat agccccacca aacaatagta
     1621 attgttctgt aatcgttgtt ttcccagcat ccggatggga aatgatcgca aaagttctgc
     1681 gattgtccac ttgttgcttt aattttggat tattcataac ctaactccat ttcttccatt
     1741 caattattta tattttctct aggcacagat tgtccgatct cttaaagaaa gacaatttca
     1801 tatagggctg tgacaaaagc cgtgtagcag tctctttttc cgagtaaacg gcgttctaga
     1861 gacagcctat cagcaataag cccacccaag ccaaaaatac gaaaagctgt ttttgcttgg
     1921 ctgctcttat tacttaatgc aggatagctt tttcacaacc tttgtcaact actacaactg
     1981 aatcagtata gcatggattc agcgaatgaa aaagccacca aaccataaga gtcaaatatt
     2041 tttttgtcag ctgactaaaa gaaaagacgt gttgcttgtt tattcaagca acacgtcttt
     2101 cataaccaag tttccaatta tcttcttggc tcgtcatctt cgaattcttt tctgaagtat
     2161 cttcgttctt cttcaggttc cgcttctgtt tcttccggat catgaaaaat gacacggatt
     2221 ttaaggattc gagaaccttc catttcttca gaaaccagcg taatattatc gacatcaaac
     2281 gataactttt cgccttcatc cggaatcatg cctaatgctg taatcaaata accagccatc
     2341 gtatctacat cactcatatg cagatcactg tcaaaagctt cattgaactc atcaatcagc
     2401 atacgtcctt ggatgatata ttcgtgttca tcgatttttt cataaagatt ctcaacttca
     2461 tctgattcat catcgatttc tccgacgatt tcttctaaaa ggtcttctag tgttgctaac
     2521 ccaacgacgc cgccatattc atctaataaa atagccatct gattctgcgt ctttttcatt
     2581 tcatataaca gatcatcaat aaagaccgtt tcaggaacga ataaaggctc ctgcatgatt
     2641 ttcttgatat ctaaattatc aaagccgaat ttatgggcag cttttagtaa attctttgta
     2701 tgaaggattc cgactacttt atctttgtct tcgttataaa cagggattct tgaatagttt
     2761 tcggataaaa cttcattcac attttcttcc acagtgtcgt tgatatcaat cataaatgca
     2821 tccgttcgtg ggaccatgac ttctcgggca actttcgtat caagagaaaa aaccccttgg
     2881 agcatttcta attcttcatt attcaatacg ccttcgtttt caagcatata acgcatttca
     2941 tctctggtca tttttgaatc ttcatcatca aaagtcatcg gcgtgatacg cgccaataaa
     3001 cttgtggaag cagaaagcag ccagacgaag ggcttagcta ctacaccaat caagcgtatc
     3061 agccctgaag tgaactttgc gacttcttct gatttattta aagcaatacg tttagggtac
     3121 aattctccaa aaacaatcga tacataggtc aaaatagcca gcacaatgat atttgcaata
     3181 ttttttgccg ctgtgccgcc acctaatacc ggagctaacc gttccgataa agtattagct
     3241 agtgaagcac cagacaaaat gttgaccaaa gtgattccta cttggattgt cgataggaaa
     3301 ttatttggat tctgcaatat ttttaaaagc ttttgagatt tcacatctcc ttcatcagct
     3361 ttttgctcga ttcgattctt attgatcgaa acaacagcaa tttcggaagc tgctaaaaaa
     3421 gcattgatca atgtcaaaac gatcaataat aaaatctgcg ctaacagcga ctgactctca
     3481 gggtcagcat tcataatcgc attctctcct tataaaatta atttttagtt tacgatagaa
     3541 aaaaacgtgg cactatagcc acgttaaaat ggtatcacaa agcaattttc tttgcaataa
     3601 aaacaagtgt actaaaacta cctacgaggt cgtagcaatt ttcttcttgt tttcattttg
     3661 cttgtcttct ttgacgattt tgattatata ggaaatgatc gtcttgcaga ttgcgtaaaa
     3721 aggaacacct aagaagatac caagcaatcc ggcaatattt ccagctacta gaagaacgat
     3781 aatgatcgtt aatggatgga ttttcagtga tttcccaatt acattaggat aaatgatatt
     3841 cccatccaac tgttggacga ttagcacaac cacacaacaa agtaatgctt ttaccggatc
     3901 attgaagact gttactagaa atgcaggtgc tagtcctaga taaggtccta aatatggaat
     3961 taggtttgtc aatcccgcaa tgaccccaaa taagaaagca taatccacac caattaccat
     4021 atatcctaaa aatgtgaagg taccaacgaa taaacattcg attgcttgtc cgctaatgta
     4081 attagccaat gttttattca gttgccccaa taactccaca atttggtttc ttcttttttc
     4141 tgggaaaaac tgttggatgt ttggcactag tttttctccg tctttcaaca tatagaacaa
     4201 gatgaatggt gctgtaatga ttactacggt tgccgaagcg atcgttccaa cgatcgaacc
     4261 taaactattg gatactccac taaggaattg ctgaatgatt gtcccgtaag aaatgtctaa
     4321 ttgctcaaaa tatttattga tatctacttc cttgaacaaa ggcaattcgg ctacctcttt
     4381 taaccagctt tctacctgtt tgatgaaatc aggcatatta gatgccaatg aggaaatttg
     4441 ctgtactaga cttgggatga cactaagtaa aatccaaata attgctgcaa ctaaaaggag
     4501 cagcacaatt gcgacagccc atattctttt gatttttgct ttcatcaaca gcttgacaat
     4561 aggattcaat aaatagtaaa gaaagcctgc aatcagtaca ggtgcaaata acgtggaaaa
     4621 aaatgtcccg atcggttcga aaataaagtt tatttctgat gaaatcatga tcaatgcagc
     4681 tatgatcaat aattcaagcg accaaaacat tagtttagac tgtctaagtt tttcaaacaa
     4741 tagatttcct cctttctttc ttactagtat atattatatt cgttaaaaat tcttttattc
     4801 tttttttatt tttgaaaact tgccatactt tttatttgtt ttattttcca gtatactata
     4861 cgaaaggaag gtggctagac catgaaagtt gtacaaacaa aagatacaat gagcaatatt
     4921 tacttagatg ctgtacggat caggcatcaa gtttttgtag tcgaacaggg tgtgcctttg
     4981 tctcgagaaa tagacaaaga tgaagcccat tgtatccact tcgtcctgta ctcagataaa
     5041 aaagaaccgc aaggaactgt acgtcttttg cctttagaaa acggaaaaat gaaattacag
     5101 cggatggcga ttctttctga atacagacac caagggttag gaaaaatatt gattgaagaa
     5161 gcagaaaact ttgctaagaa tcaaggctat aatacgattt tattaggggc acagtccaca
     5221 gctgaaactt tttacgaaaa actaggatat acagcttacg gcgatccttt tgaagatgct
     5281 ggcatgcctc atatttatat gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa
     5341 aacagcaagc ttttgagaaa aatctctcac tggcttactg ttcttttttg tgtttactta
     5401 cgcgacaatt gcttgtaacg gttataccaa atatcaatat agccttccga gaacgggcca
     5461 tctccattat tgatccagtc aaccagaatc ttcacatttt cttttaggat gaagtcaata
     5521 tcgttcgggt aattcatcat tttgctgtgc atctcatatt catcgacatc caatagtcgt
     5581 ttctcgccgt caggaaatac cttgatatcc aagtcatagt cgatatattt caaggcctca
     5641 tcgtccagca aaaaaggtga agctagatta caataatagg aaaccccctt ttctctgatc
     5701 attgctatta cattgaacca gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt
     5761 acccatcggc gtccatcaga ttcagtgact aatgtgtgat cattcacgcc gatcatagag
     5821 tgttcgcttg tttttaatac catggtatct cgccacgttc gatgcaattt gccgtcgtgc
     5881 ttgtaacttt ggatcgtcac aaactctcct tcttttggaa ctcccatagc aacccttcct
     5941 taagcagcat tttgtgcttt gtgtttgggt gttcattaca ccgacatcat aattattata
     6001 tcaataaaaa tgagctttgc ctagaaagga ttcctattgt ttcgattttt ctctaactga
     6061 tctaccagtt tcatttggac cttaggaaaa acgaccgaat caaatgcatc aggcttcaac
     6121 cacttcgaag ttttgttctc ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa
     6181 aaaaggagaa catgccattt cagatgacta aaaatatgag taacttctcc taaatgtcgt
     6241 gtctgccaaa caaagagttc ctgcttttca aatgggagat tttgctcttc ttctgctact
     6301 aggtcatcaa acagatcgat ttctggcttt gtttcccatt cttttttcaa tcgctcatac
     6361 tcctcttgtg tcacttccat cattggaaat gtccacatat tcgccagcaa tttttggcta
     6421 tctctttctt caaaataata cgctccagaa tgattttgaa gagctgcact gatataataa
     6481 acgtcttttg gctttgcttt ttttgttttt acaggaaaac tcgtttggat tcctcgtttg
     6541 ttagctaaac aaaaggcttg gatcggacaa gtctcacact ttggagaagt tggtgtacag
     6601 atagctgaac ctagatccat cattgcttgg ttgaattcac ctggatgctt ttcatcaatg
     6661 attttccgca tcgcttcatc aaagattttc ctgctagaag cttttgcgat gtctgcttca
     6721 atgcaaaaca atctgctgac tactcgcatc acgttgccgt caactgcagg ttctggaagt
     6781 ccaaatgcga tacttgcaat cgcgcctgtc gtatatggtc ctattccctt caatgagcta
     6841 atttcttcag gcgtttgcgg catttcccca tcaaattctg acatgatctg tttagcagca
     6901 gcttggatgt tccgggctct tgagtaataa ccaaggccct cccatgcttt taaaagcttt
     6961 tcttctggag catttgctag ctcttcaatt gtaggaaacc attccatgaa acgataaaaa
     7021 taatcgatca ctgtgtctac tctggtttgc tgaagcatga tctcagagat ccagatacga
     7081 taaggatcac gattatagcg ccaaggcagg tttctttttt cttgttcata ccattgaatg
     7141 aactgatctt gaaattcttt tgtttcttta tctgtccatt tttcccattc tttattcact
     7201 ttcctcttcc ttttccgtaa tgaatcgctg gatcatatcc aaatcaaatc ctttttgata
     7261 taagctttgc tttactttta gatttctttt tttaggttca aaccttaaat ttcttcgcca
     7321 tagtttatct ccttgtttga ctaaataatc atattctatt tcttgatctg cttcttgcgg
     7381 aagatcagct atcgcttgtt ggatcacttc ttgagaaaag cctttcgtca tcaatgtttg
     7441 ttggattttt ctcaataatt ctttttggct ttttccgtga ttttttccaa acgctttttc
     7501 ggctgtctga tgtgcatttt gaacttggtc ttcaaatgta tattggctga gcgcttgttc
     7561 aatgatttca ggtttcaaac ctttttgctg catctgctgc gctaatttct ttggtccttt
     7621 gtcacttaag cgcatattcg tgcgcacata actttcccca tagaccaaat catcgacaag
     7681 gtccaattct tttaagcggg ctacgatttt atttcgatct tcttgaagga tttccttttc
     7741 ttttaagtat gttcggattt ctttttccga tcgcaactga taacttaagt aattcattgc
     7801 taggtgaaaa ccgaaatcag ctccgctact cttcttgatc tcttggatag tttcttcgtc
     7861 taattcccgt ccttttaata atcgatagcg tactaataca tcttcagata cttgtaaagc
     7921 ttctccttca gataaatcta cgcgatagaa agggcctttg cctttactga ttctcgtaac
     7981 ggttaacata aacatcctcc tcgaacatat attctctatc ataccacaga aaatccccgt
     8041 aatcaggtat tatatgttag aataaaccac agaaaaaaga aaaagggaga tacttatggc
     8101 agaaacaatt gtcaaaactg gacaaacggt tcctttgaaa atcaagcgtt taggcataaa
     8161 tggtgaagga atcggttatt tcaaacggtt gatcatattt gttccatatg cactaccaaa
     8221 agaagaagta ctagtgaaaa tcacgaaagc aactcctcgc tatgcagaag gagaattaat
     8281 aaaagtcaaa aaaacaagca aagatcgcgt agtggcacca tgtcctgttt actatgaatg
     8341 cggtggctgt caattacaac acttagctta tcaagctcaa ttggatttta aaaaggatct
     8401 gcttttgcaa gcattggaaa aattcaaacc agcaggcttt cgatcttatc aacttttgcc
     8461 gacgatcggg atggatgagc cttggcatta tagaaacaaa gcacaatttc agttacgaaa
     8521 aaataagcag actcaaaaaa ttgaagctgg tttatacgaa gcaaactctc atcagttagt
     8581 ccctataaca gactgcttgg ttcaagaacc tcgaacacaa aaagtaatga atactgttgt
     8641 tcaactattg aataaatttg atgcacccat ctatgatgaa cggacaaaca gtggaatctt
     8701 ccgcacaatc atggttagaa tcggtgttaa aactggggag ttacaagttg tttttattac
     8761 tcgcagtaaa aaattcccgc aaaaaaacgc aatgatccgt gagatcaatg aacgactgcc
     8821 cgaagttgtt tcaatcatgc aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga
     8881 tgaaacgatc cacttatggg gaaaagaagc cattgaagaa caaatcaatg aagtgacttt
     8941 cgatctttct cctcgtgcct tctttcaact caatcctcag cagaccgaat tgctttatgg
     9001 cgaaggaatc aaagcattag atgtccagcc taatgaaacg atcgtggatg cttattgcgg
     9061 agttgggacg atcggcttaa gtgtagcaaa acaagccaaa gaagtacggg gaatggatac
     9121 cgttcctcaa gcaatcgctg atgcaaaaaa aaatgcggaa agattaggat atcacaacac
     9181 tcgatatgaa gtcgggacag cagagcaagt tctgcctaaa tggttgaatg aaggttttca
     9241 gcctgatggt atcatcgtag atccaccacg tacgggtttg gataacgcat tgatccaatc
     9301 attattgaaa taccctccaa aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc
     9361 cagagatctg gttaatttaa gtaaaaagtt caagattgaa tatttacagt ccgtcgacat
     9421 gtttcctcag actgcacgtt gtgaagttgt cgtgaagatg acgagactcg ctgactaaat
     9481 gaaagaggtt gtgaaaaagt ctgccctgta tcaagtaata agaacagcca aacaaaaata
     9541 gctcttcatg ttttatgaat actgtacttg tgaccgaaga gttaacagga ggacactatt
     9601 tatttaaaaa aagggttgtg acatagtttt tgtcacagcc ctttttgatt attattggat
     9661 attcacgtct atcacttgat aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa
     9721 aatcacatta tatccttttc gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg
     9781 tggaacagtt gctttgtcgt ctatttttgt gatcaattca aaatcactaa atttcaaagg
     9841 ttgattagga ttccaagttg gtttggtaat gtagtaatcc caagtacttg tccgatgttg
     9901 tgctgttaaa ttccaagtaa tatttaatgt tcctggatta accatgtttt tatgccatct
     9961 gttagatgtc tgttcatcta aaggctcaaa gccgctgact cctgcactag caatttttcc
    10021 atcaatgaat gtatttttgg tagcttcgat actttgcggt tcccattgtg ctcttccgac
    10081 attttgattt aagtttcctg ctgctgatgt tcctaggtat gcacggcttc ctggagaagt
    10141 aatataacca tgcgcaaaac ctggaatgct aaaaccgaac aaccctaaac taactaaccc
    10201 aataaacaat aacgtactaa tctttttcat gtagaaacct ccttcatttg ataaccacat
    10261 tgtaaacgct ttattgtatt aacacaaaca ttatgctttt ataattttat gttgaagtaa
    10321 aaaaggtgaa aaaagtaaga tgcagattat aacagaagta gacgagaaaa gtacaaatag
    10381 aaaacatgag aatcaaatca tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt
    10441 tcaacttttt aataacaaca attatcaatt tttttcttac ttcacaaact aaatacaggt
    10501 cttgctgtga gccttcatgg taaactacta ttatagaaag gagttagtaa aatgaagatg
    10561 ataaaagata ttcgtttttg ggtttgtgtt ataggaattg tcatattagg ctttttatca
    10621 gggttgctta gcggaaatcc cggagaatat tactattctt tgcaacttcc accatttgca
    10681 ccacctagct ggatatttgg gccgatgtgg accttactgt atatattgat gggtatttct
    10741 ctttatttgt tacttaatca caacaacaaa aaacagcgaa acaatcttgt cggtcttttt
    10801 gtgattcagt tcatttttaa ttttatatgg tctgctctat tttttaat
//
LOCUS       DAXLPQ010000072        10480 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.074, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000072 DAXLPQ010000000
VERSION     DAXLPQ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.074"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(1..270)
                     /gene="rpsN"
                     /locus_tag="ACF3UO_002417"
     CDS             complement(1..270)
                     /gene="rpsN"
                     /locus_tag="ACF3UO_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3658364.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(793..2559)
                     /locus_tag="ACF3UO_002418"
     CDS             complement(793..2559)
                     /locus_tag="ACF3UO_002418"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658365.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(2519..4273)
                     /locus_tag="ACF3UO_002419"
     CDS             complement(2519..4273)
                     /locus_tag="ACF3UO_002419"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658366.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(4383..4952)
                     /locus_tag="ACF3UO_002420"
     CDS             complement(4383..4952)
                     /locus_tag="ACF3UO_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFD3658367.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4970..6385)
                     /locus_tag="ACF3UO_002421"
     CDS             complement(4970..6385)
                     /locus_tag="ACF3UO_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658368.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(6396..7064)
                     /locus_tag="ACF3UO_002422"
     CDS             complement(6396..7064)
                     /locus_tag="ACF3UO_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFD3658369.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(7194..7778)
                     /locus_tag="ACF3UO_002423"
     CDS             complement(7194..7778)
                     /locus_tag="ACF3UO_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3658370.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(8109..8342)
                     /locus_tag="ACF3UO_002424"
     CDS             complement(8109..8342)
                     /locus_tag="ACF3UO_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFD3658371.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(8357..9307)
                     /locus_tag="ACF3UO_002425"
     CDS             complement(8357..9307)
                     /locus_tag="ACF3UO_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFD3658372.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(9304..10146)
                     /locus_tag="ACF3UO_002426"
     CDS             complement(9304..10146)
                     /locus_tag="ACF3UO_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFD3658373.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(10148..>10480)
                     /locus_tag="ACF3UO_002427"
     CDS             complement(10148..>10480)
                     /locus_tag="ACF3UO_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3658374.1"
                     /translation="QIGELSGGQFQRVLLARCLAQNADFIFLDEPFVGIDLVSERIIM
                     DTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVESVFNEENLKKAYGD
                     TIFIGEGE"
BASE COUNT         3526 a         1931 c         1365 g         3658 t
ORIGIN      
        1 ttaccaactt gcttttttta ctccaggaat caacccttga tgggcaagtt ctctaaactt
       61 aatacgggac ataccgaact ttcgcatata ccctcttgga cgaccatccg tctgatcacg
      121 aagcctcaga cgattcggat ttgaatctct tggcaattta gcgagagcgg tgcgatctcc
      181 tgcggctttt aattcctgac gtttatctgc atacttttca atcatcgcca tttgtttctt
      241 tgctttagca attttcgact tttttgccat atacctttat actcctttta ttttgattta
      301 gacacctcaa atcgtaatcg ttacgttttg acactgatac tttaccaaca agagttgctc
      361 ttgtcaacaa taaataacat gaaataaaac tcatatgaat agataactat ttgaaaacga
      421 atttatcggt acatagagat aatcaaatca tttaaaagaa tatgcagttt aggctctgaa
      481 aaataagaat tcacttttat tagtccaatc aaacacaaat accgttttaa gtagcttttc
      541 ctctacttaa aacggcaata tgaaagaaac tataactttt tattcaatct tttatgttta
      601 actggtttat cgccaatttt ttaaaacttt gattattcct tatattataa gaatagacat
      661 taagtgaact aattcaatca tactgattct ttcgtgtatt caaaattaga tgctgtttaa
      721 taaaattatt ctttttgaaa aagaattata actatatccc aaaaattgta ggttaattta
      781 aagcctattt catcatcgtg attgagcttc tttttcatag acgaatttct cagatagttt
      841 agttttcttt atgagatttt tgtatatttc tgaccttcga tacaactcat tatgagtacc
      901 ttgatcaact agttttcctt gatccatcac tacaatttta tttacctttt caatagactt
      961 caagcgatgc gatataatta gtactgtctt atcttgtatt aaacgattta aactttcctg
     1021 aatacgtttt tcattttccg catctaaact ggcagtaatt tcatctaaaa ttaaaattgg
     1081 cgcatttttc aaaaaagccc gtgctatgga taggcgttgt cgctctcctc cagaaagtga
     1141 acttccgttt tctccgacca atgtatgata accgtcaggt agtttttcaa taaagtcttc
     1201 gcagttagct aaacgagctg cttttttcac ttcctcatct gacgcttgac tatttccaat
     1261 acgtatattt tccaaaatac ttgtattaaa caaagttacc tcttgaaaaa caatagcgat
     1321 tttgctaaac aaagaagctg gagatacacg tttaatatca tacccatcaa ttaaaataca
     1381 gccttcatca taatcataca gtctagacac taatttcaag atactagttt tcccggaacc
     1441 actagcacct actaacgcag tcacttctcc ttgtttagcc gtaaaagaga tatgatctaa
     1501 aattggggta ttgttatcat atgagaaaga gacatctcgc aactcaatgt caaaagattt
     1561 cagaggacta tctgatccct cttggatact ggtttccttc atagctctaa ttcgctgtat
     1621 tttaggagct aaataaaata tttcaagcac tgcttctttc atagaatcga aggaatcctt
     1681 tatttttatt gcggctagta agtaaccaac gacgtagagt atagtcactt cacccgttaa
     1741 cagtaagtga acacctacta gaatgactac tgctaaacta acatatgaga aaatagagga
     1801 taaggccatg actgaaaaag tacttaattc tacctttaaa tgaatccttt cactctcttc
     1861 catttttttg aaaagtctgt cttgaacttt tttagataga ttaaagctat taatctcttg
     1921 ctgcaattct atagtttctt gaaattcttc cgagttttct ctcaaagtat cgtaatattt
     1981 agtattggct ttcgtttggg atttctttga taacaagatt aagacaaaac taaataacgt
     2041 tggcaaaata acagctaatc ccattttgac attaccaacc aaaagcatca ctgaaataaa
     2101 agggaaaaac agagccatac cgccggcttt aggtattgca tgactcatcg catgctcaat
     2161 accttcaacg tcagacatga tagtttgaga taaatctgat aaattatgtt ttgaaaaata
     2221 ggataatggt aaatttgaca aatcgtctgc aatttgcact cttaaatgcg cactttcttt
     2281 ataagtacta ttatataagt tttcatactc cctatctaac aaccaataca tgaaaagcaa
     2341 agtaacaaac gatacggcaa aataaagcca acggggcttt gtattttcta aaactaattc
     2401 gtctatcagc atcattataa tgaatgctgg taccatatta atgcagtata caaaaaaact
     2461 agaaatagaa gctttagtta aagcttctgc gccctgatca cttaaagcaa atttgttttt
     2521 ataaaaactt ttcattgtca agcctccaat catttgcatt ctcataatta gtgaccaatt
     2581 gtttatacac ttgatgttta gccattaatt cattatgatt tccacgttct actattttcc
     2641 cttctgacaa gacaagaatt tcatctacag atttaatgct ggataatcga tgagctatca
     2701 taataactgt tttttctttt atcagatgtt gaaaagcctt ttgtagttca tactcattat
     2761 ctggatcaat agatgcactg gcttcatcca taataacaat ctttgcatct tttaaaattg
     2821 ctctggcaat agctatacgt tgtttttctc ctcctgacag ataaactcct ttactaccaa
     2881 ttaaggtatg ctctctttcg ggaaattttt ctaaaatcga ttcgcaaccg gctaatctta
     2941 gcgcgtcaaa tactttactt gctggcgctt gaggatttgc tatagaaacg ttatcgtaaa
     3001 tactctgatt gaatagtttc gtatcttgaa agacaaaagc aattgtgtta ataattgtgt
     3061 cttttgaata gtgatttaaa ggcttaccac caattttaat ctgtccctta tccacattgt
     3121 agaaacctga aattagttta gctatcgtac tctttccgct tcctgatttt cctactaatg
     3181 cataaattct tttttgttct aaaactaagt tgaaattttc taaaacacac tcttctttgt
     3241 atgaaaagct gacattttca aatgcaatgt cacaattttt aatctgtgtc tcgttcccat
     3301 attttagttg gtcttgcttc atttctaaat aaagggagtc tagtgtttcg actgcatatc
     3361 ttgcttcaaa caagtgcata cttacataca ttattctcat gaaagaaaca aaaataattc
     3421 cacttaaaaa aaacaacatc aacaagtcaa cagctaatat cttgggagtg gtaagagaag
     3481 ttataaaaaa ggttatagga actatcaaaa tgcaaactat gccaaaaaat agccattgaa
     3541 aaagaacaaa aggtgttttc ccactcaaag aatacttata tgcaaactta gcataatcgt
     3601 taattgcttt attcaaggct ttaaatgatg ttactttagc accaaatatc tttataactt
     3661 gaattccgcg gatatattct accgtttcag agcttaacac atctaacgat tcttgatatt
     3721 tttgaataaa atttgtattc tctgtcattt tctttaacaa gaatacacca attactaaca
     3781 tggcgattag aaccaatcca attttaaagt taatgaaaaa gcctaaggca actgataaaa
     3841 caggtgttac tatggcttga gcactatctg gaatcaagtg agcaattgcc atatgtgttt
     3901 tagccgcgtt gtcatcaatt gtctttcgaa tatatcccga agaatttaaa tcaaaaaaac
     3961 gaaaacttgc ttctgttaaa ccgctaattc ccttttttct caaattagtc tctaagcgaa
     4021 acccaaggat atgagaaaat aagccagaaa aaatataaaa taaagctcct aaagttaacc
     4081 aagcaacagt ttgaaccgca taactcttag ctaaatattc atctcctaca ataattagag
     4141 actgaagaaa tttgtaaata ctgtaatatc catagactgt taatacgaca gaaaaatcag
     4201 aaaataaagt ggctaaccat ccgtagtatt tcattttagg gacataacta aataattttt
     4261 tgtatacttt cattttttcc tcccccgcat tcaatttctt ctcttattcg tttacaactg
     4321 ttaatgcttt ccgtaatagc gtaaattaga gatgtacaaa cagataaaag gtaaactacg
     4381 ttctattttt tgtatttttt taagactttt cttccaatca atacaccaat catagataaa
     4441 cttgctacaa ctaacactga aatgattccc catataccta ccgcatagtg gatcattgca
     4501 tccattgttg cagcagattg tcctttatct atccaatctt gacgaaaacg atctgtaaag
     4561 aaccatatag gaatccactg tccggcagca ctgcctaatt gcattagagc ccaagacgca
     4621 acttgaggaa ttgctcgatc atatccaaat acagatagaa taatatcagc taagatcgcc
     4681 atactaatcg aactgataaa ccaaggtaag tacgccccgc ccattaacgt aaaaaataac
     4741 aataaaacaa ttgtgtaaat agtaaaaatt ccttttctag ggtagttata gctaatataa
     4801 acaaatatga ttccagataa taatccaaaa atcccggggg atatgctgtg accaaacgcc
     4861 ccaccaatac tactaaccat tattgaaaaa aagtaaatta ctagggaaat aactgtagct
     4921 aaaccaataa aaatataatc ttttgttttc atatatattc tcctcaattc tatttcgtta
     4981 tgtcattaaa aatctgttct atcaaagttg aatcttctac tctaagtttt atatcttttt
     5041 ttattccacc attttttaaa taaataattc tattgcatgt tttataaaga aattccggat
     5101 catgagtagc tataactact gcaccctttt cttttaagtc tttaataagg tcagcaatcc
     5161 tttccatatt aatataatcc aacccacttg taggttcatc aaatagaaat aaattagttt
     5221 ttgacaatga agctatagaa accaataatc tttgtttttc tccaccggat aaatcaaacg
     5281 gtaattgatc tttcatttta taaagttcca ttttttttaa aattttttct tgctgatctt
     5341 tactaactat ttcattcccc agggctaact cgctcctcac tgattctgtg aaaaattggt
     5401 aatccatttc ttgcattact aaaaacggcg atgacaaatt ttttttattt tcgattatct
     5461 ttcctttggt agggcgaata atcttcatga gtattcttag taaggttgtt ttccccacac
     5521 cgtttttccc taccaaacca ataacatctc caactttgac atcaaaattt atgtctttta
     5581 gaatattttc ataagtaatt tcttcaactt ttaatacatc tgcacttacc ttttcgatat
     5641 agggaacttc aatcgaacta ttaaaaatgt caaatttcct taatgcgtta ttgttttcag
     5701 tttttaacaa ctgaatagtt gtagttttta cagttctatt tttaacaaat agaacttgat
     5761 caattaattc tttcaaatag taaaaacgat gttcagctat aacaatagta aatcctttat
     5821 tttttaaatc acaaagtaag tcagcaagtt tcttagtcgc tttgaagtcc aaatttgaag
     5881 acggttcatc caatataatt aatttagagt ttagcgataa actacatcca atagaaattt
     5941 tctgccgttc accacttgat agcgaaaaaa tgtttttatc taatatattt gaaagatcta
     6001 ataattcagc taattcattg attcttttat ccatatgctc ttttgtaaat ccaaagtttt
     6061 ccatcgaaaa tactaactca ctcgttgtat ttgttgtaaa gaattgtcct ctaggatctt
     6121 gacttacgta gccaatattt tttgatatac tttcttgtgt taaggattgt agcgagttat
     6181 tttcaaataa aatttcccca accaattttc cgtcataaag tcttggaata agtccattca
     6241 ttaactttaa tagtgtggat ttcccactcc cagaagaacc agtaatcaat gtaagactgc
     6301 ctttttttat tgaaaaatta aggtcaacaa gcgcttgttc cttaacatcc ttatatgaaa
     6361 aagaaacatt gttaaattca aacaattctt tcacctcaaa tcaaaatact taagaaaaaa
     6421 atagtaacgg aaaacaggat gatatagtct aataagctca tgtttgtttt atagtaagaa
     6481 cttcttttca caggagattc tatccccttt gttattgcat tagcggtcat ttcttcagca
     6541 atcatagttg cacgtataag aacgggaact aacagaaatt ccaaatattg cagaggctga
     6601 aaaaaagaca agcgaatgtt tctcattttt aaagattctt taatcattct tatttcagaa
     6661 cgataagtcg gaaagaatct gatcactact gtaatactta acattatttt tttcggtaaa
     6721 tgtatttttt ctaaagagga taataattca ttgctagtat agacactaac caacaaccat
     6781 gagatcatta cgaccggcaa cattcgaaat acaatatata aggatgtcgc aaaaaatata
     6841 gtaaaaaact ctatcttgat agcatcaata attttcatta ctaaaaacag aactgaataa
     6901 atcaagatga aataaataca tgtctttatt ttacgaaaca tcaatactaa aactgtagca
     6961 ataatgaaac accccacttg aaatatattt ccctttccta aaaaaataat gaccggaaaa
     7021 aaaatattta aagtaatcaa ggttaacgga ttgatttttg acactctttc acctccaaaa
     7081 aataagatcg cactgttatc ttaagctgat aaaaatgcac cgttattcag ataacagtgc
     7141 gatcttatca aaaagcataa ctgagaacaa ttctcaatgc aagctttttt taattaactc
     7201 agtaattcaa tccacccagg aacagaaaat tgatacaatc ttctggttaa tagcatagtc
     7261 ttttcttttg aatagctatg cttcaatata tcatagaatg tagcgtagaa tgagtaaatg
     7321 tagaagtgga tttcttcttc attaaagact aaattttgat tgatcattcc gatagtcttt
     7381 aacttatcta gacaacagac tgtctttttc gtcacaaatg atgtaatttt ttcaacaata
     7441 tcttgatatt tggttccagc tgattggaat aaaatcaaat cgaatatacg tttattctca
     7501 aaaatataat taataaatgg atctaattca ttgaagttct ctctccaact tttctctata
     7561 tctatatttt ctaagtttaa gaggtatttg gtaaactctt cattatacat attaataagc
     7621 gcattaatat gcggctgaat aatttcttca aataacgctt ccttagaagt aaaatgttta
     7681 taaaaagcac ccgtagttac gcctgcggtc aggcacagtt gccttatctt agtttgctga
     7741 aatccttctt tttcaaaatg gcttagtcca ctttctatta acttttggtg agttataata
     7801 taatctctgg tttctatggg tacttcctcc taataagatg aattaacttt attatcttac
     7861 acaggacttg aagtttcaat cgttaacgtt tattactgaa ctcattcctt agagctaaac
     7921 taatgagaaa gagcagaata actgatacaa aaagcaatcc tacaagaatt aatagactca
     7981 tctaaatcat tcaccttttc taaaataatc cgagaaagat ttaaaaaaat tatatccagc
     8041 tattaggata agtcctatca taatcactcc aatagccatt ttcttatcct ccctaaaaat
     8101 aaagtctttt acttaaaacc ttttttgtaa tcgtcaataa attttttccc tttatcagtt
     8161 aattgaaatc ctatatctaa atagtcctca tatctaagtt tagccagcat ctcacttaca
     8221 gatgctggac taacacttag aacttttgct aaatcattat tttttaattt cttttttctt
     8281 tttgataatt cctgaattgc tagtaaataa attagtatag tagtcgtttt aatttgtacc
     8341 atacctaccc tccaaattat ttcgaaaggc cttcagcaat tttatccagg ttccatttca
     8401 tcatcgcata gtaactatca ccatcttgtc ctttttctgc aattgaatca gtaaaaatcg
     8461 ttgaatagat aggaatattg gtatcttttg atactgtttt cattggtcta tcatccacac
     8521 tgctttctac gaataaggag ggaacttttg ttgtgcgtaa tttttcaact aagtgtttta
     8581 tttgatctgg tgttccttct tcttcagtgt tgatttccca aatgtaagca gaaggcacat
     8641 tatacgcttt cgagaaatat ttaaagcatc cttcacttgt aacaatcatt tttttatcat
     8701 tcggaattga agcaaattta gatttagctt ctttgtctag agaatccaat ttttcaatat
     8761 acttatctag attttcttta tagaattttt tattatcagg atctttttcc gctaactgtt
     8821 tttcaatatt tttagcgtaa ataataccgt tttctaaatt taaccaagca tgaggatctt
     8881 ccttcccttt ctcactctga ccctctaagt aaataacatc tatgccatca cttgctgcaa
     8941 aatagtcttt gttttcctct ttgttcgcat ttttaactaa ttttgtaaac caagcatttc
     9001 ctccagtttc caagttaaca ccgttataaa aaatcaaatc tgcttttgaa gttttttgaa
     9061 catcttcagg caaaggttca tattcgtggg gatctttccc aataggtacg atactgtgta
     9121 aatcaatttt atcttttgct atattttcgg taatatctgc taaaatcgaa ttagtaacta
     9181 ctacttttaa tttttcgttc gaagccactt tatctttgtc tttactattt attgaacatg
     9241 ccccgaatat aaaaagagca atcaaaatcc ccagacttcc cagtactgct ttccattttc
     9301 tcatcataac gatctctcct tctttcttaa aaatttttgt tttggtgaga ttagaaaact
     9361 aattacaaat aagaatgccg ctgttaaaac aatacttgat cctgctgcta tgttaaaact
     9421 ataaccaata aacaatccaa gcaatgatga acttgctccg actgttgcag aaataaatat
     9481 catagttttc aagctatttg catataaata tgctgtagct gctggtgtaa ttaacattgc
     9541 aacaattaat atagttccca cactttgcat agctgttact gctactaaag ttaatagaac
     9601 catcaataga taatgataaa aactgacatt catccctatt gcttttgcca ttaatggatc
     9661 aaaagaagtg attaataatt ctttaaaaaa tagaactact ataaccaaca ctaaaaccga
     9721 aacgccaatt gtaatccact tatcaatatc ttgtacagct aaaatatttc caaataaaat
     9781 atgaaataaa tccgttgagc tatttgcaac tcctataagg ataactccta gtgctaaaaa
     9841 agaactgaaa gtaataccaa ttgctgtatc tccttttatt acactattgc tttttataaa
     9901 agtaataatg atagaagcta atagaccaaa tacaatcgca ccaataaaaa aattaatacc
     9961 taaaatataa gaaattgcta ctcctggcaa aacagcatga gaaatagcat cacccataag
    10021 agacattcct cttaaaataa taaaacaacc tactgttcca gaaacaatcc ctataactac
    10081 agatgtaatt agagcattct gtaaaaagtg aaagtcatac agaccattaa taaaattttg
    10141 aagcatatta ttccccctct ccaataaata tagtatctcc ataggctttt tttaaatttt
    10201 cttcattaaa tacagattct acacttccgt gagcaattag atttcgattc aaaagaataa
    10261 tattatcaaa atacttcttt accttgctta aatcatgatg cacaattagc actgtttttc
    10321 cctgatgttt caattttttt aacgtatcca taattattcg ttcactaact aagtctatcc
    10381 ctacaaatgg ttcatctaaa aatatgaaat ccgcattttg agcaagacat cttgctaaaa
    10441 gtacacgttg aaattgtcct ccagataatt ctcctatttg
//
LOCUS       DAXLPQ010000073        10412 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.075, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000073 DAXLPQ010000000
VERSION     DAXLPQ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.075"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            112..852
                     /locus_tag="ACF3UO_002428"
     CDS             112..852
                     /locus_tag="ACF3UO_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658375.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1143..1811)
                     /locus_tag="ACF3UO_002429"
     CDS             complement(1143..1811)
                     /locus_tag="ACF3UO_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3658376.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            1945..2232
                     /locus_tag="ACF3UO_002430"
     CDS             1945..2232
                     /locus_tag="ACF3UO_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658377.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            2648..4186
                     /locus_tag="ACF3UO_002431"
     CDS             2648..4186
                     /locus_tag="ACF3UO_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFD3658378.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTSTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            4183..5148
                     /locus_tag="ACF3UO_002432"
     CDS             4183..5148
                     /locus_tag="ACF3UO_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658379.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            5135..6457
                     /locus_tag="ACF3UO_002433"
     CDS             5135..6457
                     /locus_tag="ACF3UO_002433"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3658380.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      6520..6624
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6698..7441
                     /locus_tag="ACF3UO_002434"
     CDS             6698..7441
                     /locus_tag="ACF3UO_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3658381.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            7456..8448
                     /locus_tag="ACF3UO_002435"
     CDS             7456..8448
                     /locus_tag="ACF3UO_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3658382.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            8460..9197
                     /locus_tag="ACF3UO_002436"
     CDS             8460..9197
                     /locus_tag="ACF3UO_002436"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658383.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            9187..9909
                     /locus_tag="ACF3UO_002437"
     CDS             9187..9909
                     /locus_tag="ACF3UO_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFD3658384.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(9993..>10412)
                     /locus_tag="ACF3UO_002438"
     CDS             complement(9993..>10412)
                     /locus_tag="ACF3UO_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFD3658385.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3457 a         1792 c         2171 g         2992 t
ORIGIN      
        1 tatttatgaa attcatcgct attttcttaa aataatcagc gcattgctac tgaaaacaat
       61 gaatctgtgc tattattgag aaaagttcca tttttgagaa ggatggtttg aatgaaagaa
      121 atcagacgaa aacatttccg ttttcctgcg tacgatgatg agttaggcgt aaaattaacc
      181 aacgacaaga agcgagtatt atttgacgga caagaagatc ttttgactga acagaatcag
      241 tccccgtttg aacagatgaa agaatttcat ttcacgaaca cgaacaccga gaaaatccgt
      301 cgcaagcgtc gtgcaacaaa tggattgaag tcagctccgc gtaaggaaaa tttggaaaag
      361 cataaaggaa aattaccgga ttataccggc cattaccaat cagaaatcac atcgacagga
      421 cgaaaaaaac tttttggtga ttcctctcgt tctgtcagac aaagtgaaac aaggacagag
      481 tccaagcata ctacacgaaa cgcatctgtt gacacgaagg tgcgggagcg ttcttatttt
      541 gttcctaaat atgtacccgc atcgattatc ccagacccta gagaaagcaa aatttctgag
      601 gatcatttaa tcgaatcgat gaaaaaaacg gatgactctt atctgttgtt cgatacagaa
      661 ccgacgccgt atcaagaaaa aagaaatggt gagccgtctg tacgaacatt caatcgaaca
      721 aaaacgttag aggaaacaaa gcagtcagaa gaaaaaaaat cgaaaaaaag ccatggtatc
      781 ttagaacgct cattacaagg attgatcgat gatcaaggaa actctttggg agaaaatagc
      841 tattttaaat aagtgatata caaatttata ttcggctaca gttggaaagg aaacgctgcg
      901 gcgtttcctt attttatact ctatccgaaa gtttatatcg tatcctcaaa tttttttgag
      961 tttaagcgaa ttttttctcc caataagtaa gaaaataatg gcaaaataaa aaaacaaact
     1021 attttcgcag atcgtttgca aaaatagttt atttttttat aaagaagatt ttactgaata
     1081 atatcatttt agtttacata atgatatttc tgtaaattaa ataaagtagt gaaaaataag
     1141 aatcagtgct ctaactgttc aagaggatca agtggttcaa atgtttctgt agtctgtttt
     1201 gcttccaatt ggggcaaaac agatccaatt tccagatact tcactttatt caatgtataa
     1261 gatagaatag aacagctaag taatgtatac agaaaatgtg tgagatccaa ataaagcaag
     1321 gagacaacta aaataccaaa agtaatcaag aaaagacttt tgccaatctt aatatgaaaa
     1381 tatttttcaa tggcttgata aatgatatct gttccgcctg tgcttccgcc gaatcgaaag
     1441 acgagaccgc aaccaatgcc agaaagaata cctgtcatca aactattgat cagtagacta
     1501 tctacagcaa aatgtatatg aaggctctcc cataaatgta aaaagaaaac tagcgcaaat
     1561 gttccgacga tcgtccggag aaaagcgtgt tttccaaaaa gaaacaatga gataagcaat
     1621 aaaggtaaat taaaaagcag tgaagtgaca gaaggagcga atccaaaaag attatgcaaa
     1681 agcaaagcaa taccagtaac cccaccatct gccagcttag atggaatatt gattcctgtc
     1741 acagctaatc cgtagattcc tgcgcctaaa atgattccgc acaattctgt aaataaattt
     1801 aattttttca tttctagcct cttttctttt gaaaattttc agcaacttct ttattatact
     1861 gacttatact cttacttcaa gaggaaaatg aaaaaaaatt atttttggct gtttcttttt
     1921 atttatcaaa taaggagtgg aaaaatgcga gcagcagact tattgacaat tcttacaaaa
     1981 tcacccaaaa aaacagagta tcaaggagtt tttttggctc aagaacaaaa actggtgcct
     2041 gtgacaatgg tccagataaa taaagcaaat caatttatct ttttatttga acacggcaaa
     2101 gcaccacttg ctatgaaaga catctttctt tttttgatga agaaccgtga gaaagctgtt
     2161 tattatcagt caaaagaaga actcattcct ctttatggag tgaaagagat agaaaataaa
     2221 gtggtgatat aagtaaaaat aagaaaacaa gacgtttatg atgtcaaaac aaccattttt
     2281 tacatttttg gcaaaaaagt gtcatgatac agtataatat tcgttgaaca ggccaataaa
     2341 ggtgttctcc cccacgagat ttctacttta ttggctgttt ctttttatta aaataaaagt
     2401 tgtgtgtgta aaaaagatat agctgattcc aagtgacaat ttcgtataga tttttatggt
     2461 attcgtagtg aaaaaacgag aaccaaaaag ttgatccgac tttgttgctt ggattctttt
     2521 tttgtcagca tatttagagg tatttttttc ttttttttgt tcgtgctgta aggttaaggc
     2581 aagacaagtt agttgggaaa aaggaaagaa atgtttatac ttaaagaata acagaaagga
     2641 aggtcgcatg aataatttta tacaaacatt aagtgaaaga aaaggcgagt tgctggaagc
     2701 tgcatttcaa catctgtcca tttctctcat ttctttgctg attgcagcac tgattgctat
     2761 tcctttagcg atttgggcag ccaatcataa aaaaatggca gaagtcttat tgcagatcac
     2821 gggtgtgctc caaacgattc cttcacttgc cttattaggt ttacttatcc catttgtagg
     2881 gatcggaact gttccagcat tgattgcact tgttatttac gctttgcttc cgattttcca
     2941 aaacacgtat attggtctag ctgaaattga cccgtctatt gaagaagcag cggtagcatt
     3001 tggtatgtcc agaatgagac gcttgctgaa agtagagctt cccatcgcat tacctgtcat
     3061 tatctcaggt atccgaactg ccttagtttt aatcatcggt acggctactt tggcagcatt
     3121 gatcggagca ggtggattag ggacatttat tttgttaggt attgaccgaa atacacctgt
     3181 tttgacattg attggtgcga tcagttctgc cttgcttgca attatattca gcggactgat
     3241 tcgctggttg cagcataaga aacctcgata ttccatcatt actttagcag cagtggtgtg
     3301 tttatttggc ggcgtttctt tatatcagtc tgccttgttt aaaaatgaaa ccatcacgat
     3361 tgctggaaaa ttaggagcgg aacctgaaat cctgatccaa atgtataaag aattgattga
     3421 agacaacaca aaaacagaag ttgaattaaa accgaatttt ggcaagacga gttttttgtt
     3481 caatgcactg gatcaaggtc aaatcgatat ctatcctgag ttcacaagta ctgtcctaga
     3541 aagcttggtg aaggtacctg aagcaatgaa aagtgctgat ttgacaaaag aaaaaacata
     3601 tgacgaagca gaagaattat tgaataagca attcgatatg acattattaa aaccaatggc
     3661 ttaccaaaat acgtatgcct tggcagtcaa gagatctttt gcgaacgaac atcaacttaa
     3721 aaagatttcc gatttggcag ctatctctga tcagatcaaa gcgggattca cactggaatt
     3781 tattgatcgt tcagatggat ataaaggaat ccaagaagca tatggcttga atttttcaag
     3841 tgtacaaagc atggagccaa gtttgcgtta ccaagcaatc aataatggag atgtcaatat
     3901 tgtggatgcc tattccacag atagccagct caaggagtac gatctagtga ctctagaaga
     3961 tgatcgaggg ttattcccag cttatcaagg cgcaccgctg atgaaaaaag attttgctaa
     4021 agaacatcct gaaatcgtta aagcactgaa taaattaagc ggaaaaataa cagaggatca
     4081 aatgattgat atgaattacc aagtcaatgt cgaaaagaaa aagccgacag aagtagcacg
     4141 aatcttcctg aaaaatgaag gattagtaaa ggaggaagat cagtgactaa attaatcgag
     4201 ttcaaacatg tgcaaaaaaa gtatgatgga aagtatgtca tcgatgacct aaatctggca
     4261 atcaaaaaag gagaaatctt tgttttggtt ggtccttccg gtagtggaaa aacaactact
     4321 ttgaaaatga tcaatggatt atctaaacca tcagcaggag acatctactt caaaggaaaa
     4381 tcgttaaatg aatataatct gcagaaaatg cggtggaata tgggatatgt gctgcagcaa
     4441 atcgctttgt tcccgaccat gacagtcaag caaaatattg aagtcatccc tgaaatgtta
     4501 ggttgggaaa agcagaaaag agcagaccgt gtagatgaac ttcttcaaaa agttggctta
     4561 tctcctgata tttatcgaga tcgtatgcct agagagttgt ctggaggaga acagcaacgg
     4621 atcgggatca tccgagctat tgctgcaagc ccagatgtga ttttgatgga cgagccattt
     4681 agcgcattag atccgatttc aagaaactca ttacaagaat tggttttgtc cttacacgaa
     4741 gaattgggca cgaccatcgt tttcgttacg cacaatatgg aagaagcaat caagctaggt
     4801 gatcgtattg catttatgaa ggatggagaa attatccaat gtgacacacc agagcagtta
     4861 ttgatgaatc ctaaaaacga ctacgttcgg catttctttg atgaaccgaa acagacgaaa
     4921 gagtggcgag tagaagattt agtcgtcaat ggatatttct taaatgaaat accagaaaat
     4981 gctcgtcaac aagtttgctt tgatacgcct atgaaagaag tatattcgct tctttcggtg
     5041 tatccaagca ttgtgatagt agaaaagcaa agaagtattg ggtcgctgac aagtaaagaa
     5101 atctttgctt ttttaagtcg agaggaggaa ggaaatgaaa acatatgatg caatcatcat
     5161 cggttcaggt gtgagcggct taagtgctgc ttatggattg aaagaagcag gtaaaacagt
     5221 actagtggtc gaagaagatc tatggggcgg gacttgtcct aaccgtggat gtgatcctaa
     5281 aaaagtcttg ttaagtgcag tagaggcacg taatcgggta aaacaattga gtggaaaagg
     5341 ttttaacgag atcccaactg ccaactggga agaacttcaa aaattcaaac gaacatttac
     5401 ggatccagtc ccagaaagcc gaaaaaaaca attagcagaa gctgaaatcg atcatctttc
     5461 aggaaccgct cgttttttgg atgattcatc tattgaagtc aacgaagaag tcttccatgc
     5521 ggattactta gttttggcaa ccgggcaaag acctacgatc ttaccagtgg agggaaagga
     5581 atacttgaaa actagtgcag actttttatc attgcctgta ctgcctaaag aaatcatttt
     5641 tatcggtggt ggttatattg cttttgagct agctacgatt gccaatgctg cagggagcaa
     5701 agtaaccatt gtccatcata atcaacggcc attaaaagaa tttgaggcgt ctttggtaga
     5761 ggaagccgtc catcaaatgg aagcatctgg cattcagttt gcttttggtg ttgaaaccca
     5821 aaagatcatt tcagaaggta ctcgctatcg tttagtcgga aaagagacgg aattagtagc
     5881 agatatgatt ttttgtgcga ctgggagaca gccgaataca gaatctttag cacttgagca
     5941 agcgaatatc gtctttgata aacacggaat tgcagtcaat gattatctgc aaacgagcaa
     6001 tccaaaaatt tttgcgtgtg gagatattgt ttcaaggaaa accccaaaat tgacaccagt
     6061 cgccactttt gaaggaaatt atgtagctaa gcggataacg gatgcaacaa gcgaacctat
     6121 caaatatccg attataccta cgatcgtcta cgccagtcct aaacttgctg aagtaggagt
     6181 tacaaaaagt cacgcctctt cgtcagatca agtggtagag atggatctta ccagttggtt
     6241 cacctatcat cgtgtcaatg aaccagttgc taaggctgaa ttgacctttg accagcaaaa
     6301 ttatttgatt ggtgctgcag tgattagcga gcaagcagac gaattgatcg atgatttgac
     6361 actcgtcatc aatcaaaaat tgactaaaaa agagttggat agctatatca tggggtatcc
     6421 gacattggca agtgatctct cctatttatt gaaataatca gcatgataac taaagcgctt
     6481 gttgcttttt ccttcttgtg ctacacttta aaaaatgaat acctgtttct ggggatgtcg
     6541 tagacgacat gagagtaagt tgtgaactta gacccattga acctgtcagt taatactggt
     6601 gaagggagaa acatagcaga cgcttgaagc gggttactat gtcgtgccca tttcaagcgt
     6661 tttttgttat tcatattaga agaaaggagg taacaaaatg aagaaaaatc tttatccagc
     6721 agtcagtatg gcattcattt taattatttg gcagattgtt gtcatagttt ggaaaatacc
     6781 tgcctttatt ttacccggac ctgctgctgt attttctgca ttagcggcag atgcacaagt
     6841 attactttcc cattctgtca cgacattaaa tgaagcagtg cttggtttgg taatagctag
     6901 cgttctttct tttattactg ccttggcaat ggattattgg aagtttttag aaatgtcttt
     6961 ttatccgtta ctagtgattt cacaaatgtt gccaatcatg gtgttagggc cattacttac
     7021 cctatggttt ggtttcggta tgcttccaaa agtgatcctt gttgtcttga taagctattt
     7081 tccgatcgta gtttcttttt cggatacatt gaggaaagta tcaaaagagc aaatcatctt
     7141 tttgaaaacg atgggggcag atacagggaa gatttatcga atatataaaa taccagcggg
     7201 tttatccggc ttcttttccg gtttaaaagt ggctgctact tattgtgtca gcggagcagt
     7261 cgttggagaa tggctaagcg ctcaagcagg cttagggtat tacatgatac gcgtaaaaaa
     7321 cagctaccag atcgataaag tttttgctgc gatcatttgt gtcattctat tgagtttatt
     7381 gctgaatggc gcttgttcat tattgaaaaa agggtattat cgtatgcttt atatttttta
     7441 agagaagggg atcaaatgaa aaaattatgg cttttattac cgctactgtt gcttttatcc
     7501 gcttgtggca ctgcaaaaga aacaagtagc aaacaagaaa taaaggattt gaaaaaagtg
     7561 acacttgttt tggattatgt accgaatact aatcatactg gcatctacct agcaaaagaa
     7621 aaaggctatt ataaagaggc tggtttaaat gtccaaatca tcgaaccagg agataattcg
     7681 acaagtattg gtctagtagg tgcggacaaa gcacaatttg gtgtaagtta tcaagaagat
     7741 gtcacttatg ctcacgcaga tggacagaat ataccagtca aagcaattgc tacagtgatc
     7801 aaacataata cttctggatt cgccacccta tcagacagta acatccattc accaaaagat
     7861 tttgaaggaa aaacatatgc aggttggcaa agtccaagtg aagaagctgt cttaaaagct
     7921 gtgatggaaa aagacggcgg ggacttttca aaactgacaa tggtaggaag caatggagaa
     7981 gggccagaaa gcttaggaaa atcctcagat atccaatggt actttgaagg ttgggatatg
     8041 atcaaagcaa aagaagcggg tattgaacta aactatatcc cattgaaaga attagatgaa
     8101 cggttagatt actatactcc ggtaattatt acgaatgatc aactgatcaa aagtgatcca
     8161 gaattggtac agtcttttat ggatgccacg aaaaaaggct atcaggaagc tattaaggat
     8221 ccaaatgaca gtgctaaact gttgcaaaaa tatgcaaaag aaaatgatcg gacgttttta
     8281 gaagaatcac aagcattctt gtcaaaaaat tatacggatg atcctgagaa ttggggattg
     8341 atggaagaaa aagtttggcg caattataca gcttttatgc aggaaaacgg attgatcaag
     8401 caagatgtac cttcgcaaga actattcact aatcagttta taaaatagga gtgatagata
     8461 tgtcaatcca aatcagccac ttgaatgtag tcattgaaaa cctgaaaata ttagaagaca
     8521 tccatttcac tatccctaaa gataccttta catcgattgt cgcgccaagc ggagccggta
     8581 agtcaacatt gctgaaaact ttaacaggag tccagcctat gacttctgga acgatcaaag
     8641 tagacgatca aaaagtaact ggtctccata cagcatttag ttatatgccg caagaagata
     8701 tgttacttcc ttggctgagc gtctatcaaa acgttacgtt atatcaaaaa atcaatcatc
     8761 taacaatcaa tgaagaacaa gtaagggatt atctggatat ctttgggtta aacggctatg
     8821 aacatttttt gccggaacaa ttatctggcg ggatgaagca gcgaacggcc ttgttacgaa
     8881 caatcatgaa tccttcttct tacttgcttc ttgatgaacc atttggagcg ttagatgcta
     8941 tgaccagagg gcagatgcaa gactggatgt tgaagctgcc taaaaaagca aagcggacta
     9001 ctttacttgt gacgcatgat atcgaagaag caatttattt atcagacagg attcttgtgc
     9061 tttccgcccg tccggcacat gtgattgctg agattcaagt gcctgaaaaa cgacggtcac
     9121 gtgaatggct actgcagcaa tcagagttga agcaaacgat ttatcagtta ttggcaggtg
     9181 aattagatgt taagtgatgc tcattgtcat ttagatggga gtcagagttt agcactcctt
     9241 cagcaggaac acacgatttt gacgatcatc aattgtgatt cgccagaaga atggaaggaa
     9301 aacagacagc ttgcagcaag taagactcaa gccttaagtt acggtatcca tccttggaaa
     9361 gcagatagct atacgtttga acaagttgag ccttttttga aaaaagcaag gatcatcggt
     9421 gaaatagggt tagataatat ttggacgaat gtaccgatga ctacacaaaa aaaagtattt
     9481 gagcgacagc ttgcttttgc agccataaat gagaaacctg ttgtactgca cacaaaagga
     9541 tgcgaaaaag agatcttaaa ttatatccaa gcttacccta atcactattt gatccattgg
     9601 tattcttctt tggactatca acaagactat attgatttag gctgttattt cagcattggt
     9661 cttgatttga aaaagaatcc agcagtctgg caactagcta aagcagtccc aatcgaccac
     9721 ttacttattg aaacggatgg actacatgca gcagagtggg ctttaggggg gattttttca
     9781 gaaaaagatt atgtctcact gcttgaagaa cagttaaaga caatcgctga gatcaaagag
     9841 ctatcagttg aagaagttaa aaaaaatact tatcaaaact tggaacgttt cattagatta
     9901 ggtaaataaa aaagagatgt gacacaacta gtgtcgcacc tctttttggc tttctttgta
     9961 taaaagtaaa ctgtttgatt aataaatgaa tcttagtacc aaccgtttgc ttcccagaat
    10021 gctttcgccg cttcccaaga accataacgt gaagtaacat attgttctgc tactctttct
    10081 tggtttgcag cagagtagtc accatttaag taagaagaat ctaattggta acgtccgatg
    10141 taacgtccgt tcgttgctgt gtaagaaccg cttgattctt tttgtgcgat ccattctttt
    10201 gcagagcttg tgcttgctgg agtagcagca gtttctgtta cagcaggagc aggttgtgtt
    10261 tcagcaacag gcgctgcttg tttttccgtt tgaaccgttt cttgtacaac aggttgttca
    10321 gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct
    10381 tctgttggga ttgttaattg ttgtcctgag ta
//
LOCUS       DAXLPQ010000074        10213 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.076, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000074 DAXLPQ010000000
VERSION     DAXLPQ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.076"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(43..804)
                     /locus_tag="ACF3UO_002439"
     CDS             complement(43..804)
                     /locus_tag="ACF3UO_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFD3658386.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            1124..1369
                     /locus_tag="ACF3UO_002440"
     CDS             1124..1369
                     /locus_tag="ACF3UO_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658387.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(1553..2302)
                     /locus_tag="ACF3UO_002441"
     CDS             complement(1553..2302)
                     /locus_tag="ACF3UO_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3658388.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            2488..3192
                     /locus_tag="ACF3UO_002442"
     CDS             2488..3192
                     /locus_tag="ACF3UO_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFD3658389.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            3232..3789
                     /gene="hxlB"
                     /locus_tag="ACF3UO_002443"
     CDS             3232..3789
                     /gene="hxlB"
                     /locus_tag="ACF3UO_002443"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFD3658390.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            3797..4936
                     /locus_tag="ACF3UO_002444"
     CDS             3797..4936
                     /locus_tag="ACF3UO_002444"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFD3658391.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            4948..5379
                     /locus_tag="ACF3UO_002445"
     CDS             4948..5379
                     /locus_tag="ACF3UO_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3658392.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            5393..6838
                     /locus_tag="ACF3UO_002446"
     CDS             5393..6838
                     /locus_tag="ACF3UO_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFD3658393.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            7124..8749
                     /locus_tag="ACF3UO_002447"
     CDS             7124..8749
                     /locus_tag="ACF3UO_002447"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFD3658394.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            9381..9734
                     /locus_tag="ACF3UO_002448"
     CDS             9381..9734
                     /locus_tag="ACF3UO_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658395.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
BASE COUNT         3551 a         1487 c         1954 g         3221 t
ORIGIN      
        1 aagagattga aggtaatgct cgaatgaaca ttaccttcaa tcttaatgat gcttataact
       61 aacgtaataa aaacctgaaa caaaaatagc tccgccgatg atatttccaa tataaacggg
      121 gataaaattc gagagaaatt ctaaccaagt cgcttgacct tcaaatatgg cagcaggtat
      181 cacaaaacag ttggccacac tatgctggaa accgattgcc acaaaaatca tgactggaaa
      241 ccaaatcgtt agtactttgc cggccgcatc ttttgctcca tatgataacc ataacgctaa
      301 accgacaaac caattacaac ctattccgga gcctaatgct tgccaccaag aaacagcgat
      361 tttatgatca gcaatatgaa tcacttggtc gagatagaca cctgaatgag ttaaaccaac
      421 aaagtgtcca aagaaatagg caacgaaaat tgcaccaata atatttgcaa aagtaatcac
      481 tgaccaattc ttaaccagct gtgagaatgt gactttttta tccataaagg caatcgccac
      541 agccatcata tttccggtga tcaattcacc accgccaaga aggatgacca gcaggccgat
      601 aggaaaaacc gaggcaccaa ctaaactagt caagctagcc atagattctg ggatagaagc
      661 agagactcgt acgtatgcca aataacctag agaaatcatg gctcctccga taaaacctaa
      721 aatcagttta gctaagatag gtttatgtat tttttttgtt ccaagatgaa tactgagttc
      781 cataatttct tctggtgtgt gcataatact tcgattccta ctttcttaat gaattttcat
      841 gtgataaaat atagtgaaaa aaatcacatt ttctttgttg attatatcat cttattattt
      901 atatgtgcat attattgtaa aattttctat ttaatcacat ttgattctaa aaaagaaaca
      961 aaaataaaag tcatgtatat ggtggtcaaa aagtaaataa tatcagttat caaatttcct
     1021 gtaaattttc ttgaaactac agcatattat tacttcaaaa caatctacat tttttataaa
     1081 aaaggaaatg aataactgaa aaaattatta taggagagaa aaaatgtcaa aatctaaaaa
     1141 aaatatcacc ataattggtt taggcttaac cgtatattta tttacagaat ttgtttatag
     1201 acatgtgaat ttatttgcag aacctttatt tgtattatac gaatcaaatt cctcaatcgt
     1261 cagtgaactt gctaatttaa tgatagcatt gctgtttact cccgcgttga gagtcataac
     1321 tattttggtc tgtttagtgc tattgttttt tgttaataaa aagaaataac gtagtatttc
     1381 aaaagacaaa gaagtgggat gatgattgct atagtatgtt atacgtggtg ctaggtaagt
     1441 gagaataaac aaaaaaggaa acacgcaata aagtttattt caaaacttta ttgcgtgttt
     1501 cttttttaga ttttttatat ctgttgcttt agtagttacc aatagttttc gcttaatcaa
     1561 tcaaaacgat tttttgttta ttgtattctt tacgaacctt ttcaggaatt tcttctgaaa
     1621 taagataggt aaggtcttca attggaccga cgatatgatt actgatggtg ccgaatttat
     1681 cattagttat catcccaagt acttcagtag aaatacgtat catctcacgt ttaatgtcgg
     1741 attcttgcat agttggcacg ctcgttccaa catctagatc tatgttataa atacccataa
     1801 tataaaggtc ggctcgaatg ttttgtagtt gcttataagc ttgtacccca atattgatca
     1861 tagattgttt ataaaaagta ccgccaatat tgataatttc caaattagga tgctgtgcta
     1921 atgctatggc aatcggcggg ctattggtaa tgattgttgc acgaaaatct tgtgggattt
     1981 cttttgctaa agccaagtta gttgtacttc catcaatgat gatgacagat tcttctttta
     2041 aaaaagggag ggctttatga gctaatgcag ttttttgttc gctagctaca gtttctcggt
     2101 agttaaaatt ggtaattggc ggaccaacac gtaaagcgcc gctgtgtact ctttttaaga
     2161 gaccttggct atccaaatct ttcaaatctc gtcgaatcgt gtcttcggat acattgaaac
     2221 gttgacttaa atcactagcg ataacttttt gttctgcgtt taataaatct agaatttttt
     2281 gatgacgttc taatttcaac atgttgcgtg ctccttctta tttattcttg tttatcatgt
     2341 catttatgcg tttttatgtc aataatttcc gtttttaata cactaaaaag gcataaacaa
     2401 gcaaaaacaa aatattttta tgcagtttta tgttgactag tatttgttaa gcggttacaa
     2461 tgagggggta attaaaggag ggaatgtatg gagaaaaaaa ttattttgtc gccttcactt
     2521 atgtgtgggg atctagcaaa tttggaagga agcatccaag aactagaaag tattgggatg
     2581 gattccttgc atattgacgt gattgacggt tcttttagtc ccagtatgcc tttagggatc
     2641 gaaacaatca aaagaattag agaaatcact tcaatgaatt ttgatgtaca catcatggct
     2701 aaggataacg ataacgaatt ttttattgga gaaatgttga aaattggcgt agagagcatt
     2761 acttttcatt atgaaacaag cctccatatt gatcgatata tccagctcat caagaattct
     2821 ggaacaaaag tagggatagc tttgaatcca gcaactccgt taaatgtatt acaatatatt
     2881 ttacccgaga ttgataggat ttgtttgatg ctgattaatc caggttttgc aacaaacaag
     2941 tcagaaaaac aagtttctta cgcgctaaaa aaaattacag atctttgcca gttagtaaat
     3001 gagaaagagt tagcagtaga tatccaagtg gatggacggg tatcgttaga aacgatcccg
     3061 ggattattag atgcaggcgc aacaaatctg gtattaggaa gtacaagttt gtttcttaaa
     3121 ggaaatacat tagcagaaaa tcaaaaacta ctttatcaag cgatgaagca atcagttagg
     3181 aaaaatcaat agatgtagtg gtcctgaata atagaaatgg aggggaaata gttgagttat
     3241 aaggcggcga aacaaaatat tgtaagagaa attactgaaa cattagaccg tatttcttca
     3301 aaagatgtgg aacaattgat aaagaaaatt gaaaaagcgg aacgagtttt tttcgtgggg
     3361 gttggcagag tactgttagc gctagaagga atggcaaaac gcttagggca tctaggaatt
     3421 cagacagtag tcgtaggaca aatcactgaa ccggcaatta cagataaaga tttattgatt
     3481 gttggttctg gtagtgggga aagtgctttc ccactaacta ttgcaaaaaa agcaaaggaa
     3541 tttgggtccc aagttgccca tataggatca aacccagaca gcacaatgaa agaatattca
     3601 gatcttttta ttcgtatacc cgtacaaaca aaattagcgt taccagagga aatttcttct
     3661 atacagccaa tgactagcct gtttgaacaa agtgttcttt tgttaggaga tagtattgct
     3721 ttagtgatga tagaagaaaa agcaattgat atgtcaaagt tgtggcaata ccatgctaac
     3781 ttagagtagg tgaaaaatga aagcggtaca ttttggagca gggaacatcg gcagagggct
     3841 tattggacaa attctacatc agaatggatt cgatctatgt tttattgata cgaatcctga
     3901 actgatccat caattaaatc aagataaggg ttatactatc gaaattattg atgaaatgaa
     3961 caggagtgat ttcattgatc atgttgtggc actgaatagt ttatccgagc tagaagaggt
     4021 gattacagca acaaaaaatg cagatatctt aacaacatct gttggcgcaa taaatttagt
     4081 aaaaattgca ccgatcattg cgcaagcctt aagtaagcga tttgaacaaa agcatagcat
     4141 caatatcgta gctaatgaaa atgtgataaa tgcaagtgat gtgttgaaaa aagaaattta
     4201 ttctttgctg tcagaaaaag aacaagagaa ttttgatgaa tatgcatatt ttgtgaatac
     4261 ggcaatcgat cgacaatctt taggaaaagt tcttggagga aaaatgatct ctgttgtcga
     4321 accttattat gaatggataa tggatcgaca gcagttagat ccaactacat cttttgatat
     4381 gaaaaatgta aatttggttg atgatatgga gccttacatt gagcgaaagc tttatatcgt
     4441 taatgctgct catgcggcag tagcttattt aggcgcactg aaaggatata agacgattca
     4501 agaagcaatc caaaatatgg agattttcaa tctagtcaag caatttttaa tggagaatat
     4561 agagtacttt gtacaaaaat atcatttttc tagagaagaa ttaacatctt ttgtggaaaa
     4621 aacattaaac cgtcatggga atcagaaact ctccgatgaa attactcgtg taggaagttc
     4681 ccctattcga aaattaggcc ctaatgatcg tttaattgct cccatagtaa aactagattc
     4741 atatcattta ccttacgatg caggaataaa agtaattgct gcgggatatc attatcggaa
     4801 tcttgctgat ccagaagctg aacaactacg tcgaatgatt gtaaatgatg ggttgaaagc
     4861 aacgattaaa aagatttctc gtttggaagg taagctgctg aatgaagttg tcgctgctta
     4921 tgagtcccag atttagagga ggagaatatg ctaaaagaac aattgtcagg aaatacaatg
     4981 tttatggatg cgatcgattc atggcaagag gcaatccgag taagtgcgcg tcctttgata
     5041 ggaaagggaa taatagagga aagctatgta caagcgatga tacaaaatgt gttggataac
     5101 ggaaattata ttatattact gccactagta gcaatgcctc atgcgcgtcc agaatttggg
     5161 agcaaagggg tcgggatgag ctttttatgt ttagataagc cagtcatgtt cccaagtgaa
     5221 gaaccagtaa aattcttctt taccttttct tctgattcgc caaagggaca tttagactta
     5281 atggccaatc ttggagaatt gctgagtgat gaaaaaatgt atcaaaaatt attcgatgtg
     5341 aagacagaaa aagcattgtt agatttgata aagaagtaaa ggagagaaga aaatggaggt
     5401 agcaaacaaa aaaaaacgag tctccatgcg agctaaagtt caagcgattg gcggtttctt
     5461 aacaaatatg gtattgccaa atataggcgc atttattgca tggggaattg ttactgcatt
     5521 attcattcca actgggtggt tcccaaatga atctctgaat gaactcgtaa gtccgacagt
     5581 cagctatcta ttgccgttac tacttgccta tactggtggt cggatggttg gtggtacacg
     5641 tggagctgtt ttaggtacaa tcggaacaat aggtttgatt attggtgctg acataccaat
     5701 gttcatggga gcaatgatta tggggccact tggtgggtgg atgatgaaaa aaacagatga
     5761 ttttttagat gggaaagttc ctgctggttt tgaaatggtc gtcaataatt tttctatagg
     5821 aattattggt ttcatactga tgtgcctttc ttatctggta gttggaccaa taatccaatc
     5881 agctaatcaa tttgtaacga gtgcaattga agcattagtt tcaactggtt ttttaccgat
     5941 actgtcctta atcaacgaac cggcaaaagt cttattttta aataatgtta ttgaccaagg
     6001 tgtttattat ccattaggta tgcaacaaac attagaggca ggcagatcaa tttatttcat
     6061 ggtagcatca aatcctggcc ctggcttagg actattgtta gcttattctt tatttggtaa
     6121 aaaggcagca aaacagacag caccaggtgc aatcatcatc cattttttcg gcggaataca
     6181 tgagatttat tttccatatg tattaatgaa accactcact atattatcta tgattgctgg
     6241 tggaatgaca ggaatcatca cttttgaatt atttgatgcg ggcctggtag caggtccaag
     6301 tccaggttct attttttctt atttagctct aacgcctcgg ggaaattttt tgggtgtcat
     6361 ggcgggagtg gtcacagcaa cactggtttc cttttttgta acatcagtaa ttttaaaagc
     6421 agataaatca acagatgaag acagaaattt tgaactatca gttcaaaaat cgaaaacgat
     6481 gaaatcagaa ggaagaaaat tattaaaaga agaaaatgct agagaaatat gtaccgagaa
     6541 aaaagagatg aataaaattt cctttgcttg tgatgcagga atgggaagca gcgcaatggg
     6601 cgcaacaata ttcaagaaaa aattgcaaaa agcaggtatt actgatgttg agataaaaaa
     6661 ttatcgaatt gaagaggtac cagaagatag tgatttggtg atcgtacatc aagatttgga
     6721 ggaacggact agaaaagcac atcctaacat gaaaattgtg acattaaaga attatttgca
     6781 agatccagta atcaatggat tagcagaaga aatcattgga ttaaaaacag aagactaatt
     6841 tatgggaatt tttgattaac ctttattaaa attattttgc ctaatataaa aaggttgtga
     6901 catggcttgt gtcgcaacct ttttttgtcg cacaaataat taatcggata ttttatgttc
     6961 atattttttg tgatcaacga gaactgatgg ggcaaagata cattttagat acttttaact
     7021 gttaatttac aaaacaaggt gaaacgaata gaaaaatgaa aaaatcgata cggaagaata
     7081 tgtttgatta aaacatgcat gaagagaagg aggttgatga tacatgaaaa aaatatattc
     7141 aaaggaaatc gattgtttta gaggcattgc tgttttagca gtgatatttt atcatttgcc
     7201 aaatagtttg ctgccaggcg gattgcaagg agtaacgatc ttttttgtgg tttctggttt
     7261 tttaatggct aaaaatacga taagagatga aaaaaacaga caattcagtt ttttacattt
     7321 ttactataag cgtatcaaac gtatttatcc atttttactg ttttctttgg tcgtattcat
     7381 tttcatacta gggattagca acattcgatt gataggaaac attcgtagtg agctacccag
     7441 tttgattttt ggctataaca attggtggca gctgaatcaa ggagtatctt attttgactc
     7501 ttactttaat gcttctttat ttaaacatta ttggtcgctt tcagttgaac tacaattcta
     7561 tttgatatgg ccatttttgt ttattgtcat taagcgtatg agaagaaaac aagtgtttta
     7621 cttaatctat acattgattt ttgtttctat tctttttagt ttgtttttac cttcaactaa
     7681 ggcatattat catacgatag ctaaactttt tccattttta ttaggagttt gggggtattt
     7741 taatcgaata actattggcc gtttctttga acaaaacact tttagtaaaa tctggctttt
     7801 attactagct agtctttgtc tgattctgtt cccgattttt ccttatacac taaatgaact
     7861 actgatcagt atttgttttg ctctattgtt agccagtgtc gatgatatga acattgcaaa
     7921 aaagaccaaa atcgctagta caaaactttc ttttgtagga aaaatcagtt atgaacttta
     7981 tttggtgcat ttcccagtat tgattgctct gacaaatcta ttcaaacatc accattggaa
     8041 atatttggat atcgcaggtc tattcactgt gtttttatgt acattactca tgattacttg
     8101 ctttagaaaa ggagtgcaaa agatgagatc acccaaaatt tggacagcta tggcactaat
     8161 gataatcgga gtttctgtac tggtattacg tgctcctgcc agtcgactga ccgctgacca
     8221 aaatcagttg caaagtttat taaaagaaaa ctctagtaaa gcaaatgcag gagaaaatct
     8281 gttgtcacaa gagaagaaaa tattatttat cggtgattct gttatgctgg gggcgtatca
     8341 ggaactaaag gagacattta aaaaagaagc attggtagat gcaaaagaat caagacaaat
     8401 cactgcgtta ccagaaatct taaaggagca taaagattta gtttcttacc aacaaatagt
     8461 gatcgggtta ggaaccaatg gtgtgataac agatgaagct atagaacaaa caatgtcttt
     8521 gctgaaagat aaaaaagtat actgggtaaa tataaaagca ccaactggct ggcaagatac
     8581 gataaatgcc acattagcta cattgccaaa tcagtattct aatataacga tgatcgattg
     8641 gtatagtgag agcaaaaatc atcctgaatt tttttatgat gatgaaaccc atttgaatga
     8701 aagtggacgt acagcttatg caaagtatat tgcttcagtt attcaataag gtagtgatta
     8761 cgtgtgttaa ccttactttt tcctaatagg tgaatcaatt taaataaaaa atacttcata
     8821 tgataaacgg tgtttaagag gaggagcttt ttaatattcg tggtaaaaaa gagatgggcg
     8881 aggtcgttaa ctgagagctt cttggaaaga aatcgctttg gatttatcct ctttgttata
     8941 cagaacatga gcgagacgac aatactagga tgtatgttct gatcgaagtt ttatggttac
     9001 aagcagcaat cagcttagat aaaattaagg atcgtaggaa ccaagtaaag aaggctgtta
     9061 gtaaagaaac aaacgatcaa gtatgtttta ctcttaagaa gatgcagtga ataaataata
     9121 gtaatataat gctagaaggg actgtgacaa aagacgtgtc acagcctttt ttgttatttt
     9181 aattatcgtc cagtcttttt ttataaatga ttgcttaagc attaaatatt aaaaaatata
     9241 gagttcaaaa ttactgcaca attagatgaa aaatttgaac aacaaaaagt gtatttttat
     9301 actataatag cttttgaatt tagttactct attcaaaagt tatgctatgg acaagaaaaa
     9361 gaataaatag aggtgagaaa atgaatagtt tcaagaaaaa atttgtgagt agatttttaa
     9421 atatgaaaaa tttttttgaa aaaaagggag attatgatgc atataattat gtattaaatc
     9481 tagaaaagca aacatattat acactacgta aaaacgatga taatgacttt tggactatgt
     9541 tacctaaaat gctttcgatt gactctaagc tttccctttt agaggaattt attaatttag
     9601 acattgaaga attttgcggg ggaaaagagt taattaatat ggtagagagt gattatcata
     9661 cctattataa agaaagttgt ggatacaaag tggatgagca atgtccacaa tcaattattt
     9721 tttacattga gtaatatgaa ctattaagca ggaaagcaac tagaagctac tgatttagta
     9781 tttacaaata taaactatat tgctaacaat tattttctag aaggaataaa agaactaaga
     9841 atcaagacgt tatcttgatt cttagttctt ttaacatgga aaagatggat aatgcactgt
     9901 taattcatga tgcatcatca gaaaagttgg aaggagaaga tagaaatcat taaatgattt
     9961 ctacagatgg taaatgaaaa aacaaaatat tagcaaaaat ttgcctaaat agatagtaac
    10021 actttctaaa ttaaatacaa gcgcattcat aaaatgttta tacaaatatc tatgtgataa
    10081 aaattggata tgttcacaat aaataggaat taaaataacg aatttacgtt tgtttttatt
    10141 taccaatcaa attatcttaa tgcaggaata aaaaattaaa ttacatattg ttaatcattt
    10201 acatctccat taa
//
LOCUS       DAXLPQ010000075        10022 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.077, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000075 DAXLPQ010000000
VERSION     DAXLPQ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.077"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..722)
                     /locus_tag="ACF3UO_002449"
     CDS             complement(<1..722)
                     /locus_tag="ACF3UO_002449"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3658396.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="ACF3UO_002450"
     CDS             complement(727..1494)
                     /locus_tag="ACF3UO_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3658397.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1983..2408
                     /gene="lacA"
                     /locus_tag="ACF3UO_002451"
     CDS             1983..2408
                     /gene="lacA"
                     /locus_tag="ACF3UO_002451"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFD3658398.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2425..2940
                     /gene="lacB"
                     /locus_tag="ACF3UO_002452"
     CDS             2425..2940
                     /gene="lacB"
                     /locus_tag="ACF3UO_002452"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFD3658399.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2951..3883
                     /gene="lacC"
                     /locus_tag="ACF3UO_002453"
     CDS             2951..3883
                     /gene="lacC"
                     /locus_tag="ACF3UO_002453"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFD3658400.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3886..4866
                     /gene="lacD"
                     /locus_tag="ACF3UO_002454"
     CDS             3886..4866
                     /gene="lacD"
                     /locus_tag="ACF3UO_002454"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD3658401.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4894..5211
                     /locus_tag="ACF3UO_002455"
     CDS             4894..5211
                     /locus_tag="ACF3UO_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3658402.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5211..6917
                     /locus_tag="ACF3UO_002456"
     CDS             5211..6917
                     /locus_tag="ACF3UO_002456"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD3658403.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7059..8465
                     /gene="lacG"
                     /locus_tag="ACF3UO_002457"
     CDS             7059..8465
                     /gene="lacG"
                     /locus_tag="ACF3UO_002457"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFD3658404.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8488..8761
                     /locus_tag="ACF3UO_002458"
                     /pseudo
     CDS             8488..8761
                     /locus_tag="ACF3UO_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
     gene            8782..9681
                     /locus_tag="ACF3UO_002459"
     CDS             8782..9681
                     /locus_tag="ACF3UO_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFD3658405.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3164 a         1690 c         2006 g         3162 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaagaaa acaaataaaa aaaacaaaaa ataaacaaaa aagtgttgct
     1861 ttttgtttga atgattgata ttatataaac aaagaaatga tgaaaacgtt ttttcgaaca
     1921 ttttgcaaaa tgttttctac ttctacgtag catttctttc taaaatttag gaggtggtca
     1981 aaatggctat tgttgttggt gcagatctca aaggtacgag attaaaagat gttgtgaaaa
     2041 attttcttgt agaagaaggt tttgaggtaa ttgatgtgac taaggacgga caagattttg
     2101 ttgatgttac cttggcagtt gcctctgaag taaataaaga tgagcaaaac ttaggtattg
     2161 taattgatgc ttatggagct ggtccattca tggtagcaac taaaattaaa ggtatggttg
     2221 cagcagaagt ttcagatgaa cgctcagctt atatgacacg tggacataac aattcacgaa
     2281 tgattacggt tggcgctgaa atcgtcggtg atgagcttgc taaaaacatc gctaaaggtt
     2341 tcgtcaatgg taaatatgat ggcggacgtc atcaaatccg agtagatatg cttaacaaaa
     2401 tgtgttaaga aaaggagtta aggaatgaga atcgcaattg gatgtgacca cattgtcaca
     2461 gatgaaaaaa tggcagtatc agaattcttg aaatcaaaag gacatgaggt ccttgatttc
     2521 gggacatatg accacgcacg tactcactac cctatctatg gtaaaaaagt cggtgaagca
     2581 gtagtaagtg gtcaagcaga cttgggagta tgtatctgtg gtacaggtgt cggcattaac
     2641 aatgcagtca ataaagttcc aggtgttcgc tcagcgttgg ttcgtgatat gacatcagct
     2701 atatatgcaa aagaagagtt aaatgcgaat gttatcggtt tcggtggaaa gattactggt
     2761 ggtcttctta tgaatgacat cattgaagct ttcattgaag ctgagtacaa accaacagaa
     2821 gaaaataaaa aattgattgc aaaaatcgaa cacgttgaaa cacataatgc acatcaagca
     2881 gatgaagatt tctttacaga attccttgaa agatgggacc gtggtgacta ccacgattaa
     2941 ggtataacaa atgattctga cagtcacact aaatccttca gtagacatct cttatcctct
     3001 agaaacattg aaaattgata cagtgaatag ggtgaaagat gttagtaaga cagctggtgg
     3061 aaaaggctta aatgttacta gagtcttgta tgaatctggt gataaagtta ctgctacagg
     3121 tttcttaggt ggtaaaattg gtgaatttat tgaaagcgaa ttagaacaat ctcctgttag
     3181 tccagctttt tataaaatct caggaaacac tagaaactgt attgctatct tacacgaggg
     3241 taaccaaaca gaaattttgg aacaaggacc aacaatttct catgaagaag cagaaggctt
     3301 tcttgaccac tatagcaatc ttattaaaca atcagaagtt gtgacaattt caggaagttt
     3361 accttcagga cttcccaacg attattatga aaaacttatc caacttgctt cggatgaagg
     3421 agtagcagtc gttttggatt gttcaggtgc acctcttgaa acagttctaa aatcgtcggc
     3481 taaacctact gccatcaaac ctaataatga ggaactttca cagttgcttg gaaaagaagt
     3541 aacaaaagat attgaagaac tcaaagacgt tcttaaagag tcacttttta gtggtatcga
     3601 atggatagtg gtctcattag gtcgaaacgg tgcctttgca aaacatggtg atgttttcta
     3661 taaggtagat attcctgata tcccagttgt taatccagtc ggatcagggg actcaacggt
     3721 agctggtatt gcatcagctt taaatagtaa aaaaagtgac gctgacttat taaaacatgc
     3781 gatgacattg ggtatgttaa atgctcaaga aacaatgaca gggcatgtga atatgactaa
     3841 ttacgaaaca ctaaactcac aaattggagt aaaagaggta taaaaatggt acttacagaa
     3901 cagaaacgca aatctttgga aaaaatttca gataaaaacg gtgttatctc agctttggca
     3961 tttgaccaac gtggtgcttt gaaacgtttg atggcacagt atcaagatac agaaccaact
     4021 gtagctcaaa tggaagaact aaaggttttg gttgctgatg aacttacaaa atacgcttct
     4081 tcaatgttgc ttgaccctga atatggactt ccagcaacaa aagcattgga taaagaagca
     4141 ggtcttcttc ttgcctatga aaaaacaggt tatgatacat caagtacaaa acgtttgcct
     4201 gactgcttgg atgtttggtc tgcaaaacgt atcaaagagc aaggcgctga tgccgttaag
     4261 ttcttgcttt actatgatgt agacagctca gatgaactta accaacaaaa acaagcttat
     4321 attgaacgtg ttggttctga atgtgtcgct gaagatattc ctttcttctt ggaaatcctt
     4381 gcttatgatg aagaaatctc agatgcaggt tctgttgaat atgcaaaagt gaaacctcgc
     4441 aaagtcattg aagcgatgaa agttttctct gatccacgct ttaacattga tgttcttaaa
     4501 gtagaagtac cagttaacgt taaatatgtc gaaggttttg ctgatggtga agtggtttac
     4561 agtaaagctg aagctgctga cttctttaaa gcacaagaag aagcgactaa ccttccatac
     4621 atctacctaa gtgcaggtgt atctgctaaa ttgttccaag aaacattgca atttgctcac
     4681 gactcaggtg ccaagtttaa tggtgtgctt tgtggacgtg ctacttgggc aggatctgta
     4741 gaaccttaca tcaaagaagg tgaaaaagca gcacgtgaat ggttgcgtac tactggattc
     4801 gaaaatattg atgaacttaa caaagttctt gttaaaacag ctagtccatg gactgataaa
     4861 gtatagtaaa aacataaaac ggaggatatt gttatgaaca gagaagagat gactctctta
     4921 gggtttgaaa ttgttgctta tgctggagat gctcgctcta aacttttaga agcgcttaaa
     4981 gcggctgaaa atggtgattt cgctaaggca gatagtcttg tagtagaagc aggaagctgt
     5041 attgcagagg ctcacaattc tcagacagct atgttggctc gagaagcttc tggggaggaa
     5101 cttccataca gcgttaccat gatgcatggt caggaccact taatgactac tgtcttatta
     5161 aaagatgtga ttcatcacct catcgaactt tataaaagag gagcaaaata atgcataaac
     5221 tcattgaact tattgagaaa gggaaaccgt tctttgagaa aatctctcga aacatctatc
     5281 ttcgtgctat tcgtgatgga tttatcgctg gtatgccagt catccttttc tcatctatct
     5341 ttatccttat tgcctatgtc ccaaatgctt ggggattcca ctggtcaaaa gacattgaga
     5401 ccttcttgat gactccttat agctattcga tgggtatcct agcattcttt gttggtggta
     5461 ctaccgctaa agctttgacg gactcaatga accgtgacct acctgcgacc aatcagatta
     5521 acttcttatc tacgatgcta gcgtctatgg tagggttcct tttgatggca gctgagcctg
     5581 caaaagaagg aggcttcttg acagccttca cgggaacaaa aggtcttttg acagcattta
     5641 ttgcagcctt tgtgacagtt aatgtttaca aggtctgtgt gaaaaataat gttactattc
     5701 gtatgcctga agaggttcca ccaaatatct ctcaagtatt taaagacttg attccattca
     5761 ctgtagcggt tgttctcctt tatggatttg aactcattgt taagggaact cttggtgtaa
     5821 ccgttgcaga atcaatcggt acccttcttg ctcctctctt ctcagctgca gatggttacc
     5881 ttggaattac acttatcttt ggtgcttatg ccttcttctg gtttgttggt atccacggtc
     5941 cttcaattgt cgaaccagca atcgctgcta tcacttatgc caatatcgat gccaacttgc
     6001 atcttatcca agctggacaa catgcagata aagttatcac ttctggtact caaatgttta
     6061 ttgttaccat gggtggaaca ggagctacat tgattgttcc attcttgttc atgtggattt
     6121 gtaaatcaga acgtaaccgt gccatcggac gtgcctcagt tgttccaaca ttctttgggg
     6181 ttaatgagcc aatcttattt ggtgcaccaa tcgtattgaa tccgattttc tttgtaccgt
     6241 tcattttcgc tccgattgtc aacgtttgga tctttaaatt ctttgttgac acattgaaca
     6301 tgaactcatt ctctgccaac cttccatggg ttactcctgg tccgttggga attgtactcg
     6361 gtactaactt ccaagttcta tcatttatct tagccggact cttggtagtt gttgatacta
     6421 tcatttatta cccatttgtt aaggtatacg atgaacaaat tcttgaagaa gaacgttctg
     6481 gtaaaacaaa cgatgctctt aaagaaaaag tagctgcaaa cttcaatact gctaaagcag
     6541 atgccgttct tggaaaagca ggcgttgcta aagaagatgt agcagcaaac aataatatca
     6601 caaaagaaac taatgtcctt gttctttgtg caggtggagg tacaagtggc ttgcttgcca
     6661 atgccttgaa caaagcagca gcagaataca atgttccagt caaagcggca gcgggtagtt
     6721 acggtgctca ccgtgaaatg ttgccagagt ttgacttggt tatcttggct ccgcaggtcg
     6781 cttcaaactt cgatgatatg aaggctgaaa cggataaatt gggcattaaa cttgcaaaaa
     6841 ctgaaggagc tcaatatatc aaattgacac gtgatggaca aggtgctctt gcatttgttc
     6901 aacaacagtt tgattaataa atttgtaaaa gttatttgag acgagattat tctttcagtt
     6961 ccttataata ttgttaacca tatcattgca tttcatttcc ttggtttccg gaactcagaa
     7021 tatcgtctca aatgcttttt ttgaaaggat ttatagttat gactaaaaca cttcctaaag
     7081 attttatttt tggtggtgct acagctgctt atcaagcaga aggtgcgact cacacggatg
     7141 gtaaaggccc agttgcatgg gataagtatc ttgaagacaa ttattggtac acagcagagc
     7201 ctgcaagtga tttttaccat aaatatcctg ttgatttaga attagctgaa aaatatggcg
     7261 ttaatggtat tcgtatttca attgcctggt ctcgtatttt cccaactggc tatggcgaag
     7321 taaatgaaaa aggtgttgaa ttctaccata atctttttgc cgagtgccac aaacgtcatg
     7381 ttgagccatt cgtgactttg caccactttg acacaccaga agttcttcac tcagatggag
     7441 atttcttaaa ccgcgaaaat atagaacact ttgtagatta tgccgctttc tgttttgaag
     7501 agttcccaga agtaaactac tggacaactt tcaatgaaat tggcccaatt ggagatggtc
     7561 aatacttggt tggtaaattc cctccaggca ttcaatatga tcttgccaaa gtcttccaat
     7621 cacaccacaa tatgatggtt tctcatgcac gtgctgtgaa attgtataaa gataaaggtt
     7681 ataaaggcga aattggtgta gtacatgcgt tgccaaccaa atacccttat gatccagaaa
     7741 atccagcaga tgttcgtgcc gctgagttag aagatatcat ccataacaaa tttatcttgg
     7801 atgcaaccta ccttggacac tattcagata aaacgatgga aggggtcaac cacatcctag
     7861 ctgaaaatgg tggagaactt gatcttcgtg atgaagactt ccaagcactt gaagcagcta
     7921 aagatttgaa cgatttcctt ggtatcaact actacatgag tgattggatg caagcctttg
     7981 atggtgagac tgaaatcatt cacaatggta agggtgaaaa aggaagttct aagtaccaga
     8041 ttaaaggtgt tggtcgccga atcgcaccag attatgtgcc tagaacggat tgggactgga
     8101 ttatttatcc tgaaggcttg tatgaccaaa tcatgcgatt gaaaaatgat tatccaaact
     8161 acaagaagat ttacatcact gaaaacggtc ttggatacaa agatgagttt gtagataata
     8221 ccgtttatga tgatggtcgt attgattacg tgaagaaaca cttggaagtt ttatcagacg
     8281 caattgcgga tggtgcaaat gttaaaggtt acttcatctg gtcacttatg gatgtcttct
     8341 catggtcaaa cggatacgaa aaacgttatg gactattcta tgtagacttt gacacgcaag
     8401 aacgctatcc taagaaatca gctcattggt ataagaaagt agcagaaact caagtgatag
     8461 agtaatatta cttgaaaatg taaaaaattg ttatccgata ctttagaaaa agtacaacac
     8521 ttatttagac caggctttga aaaggtatat attgttagtt tcgaagattg tcctatgatt
     8581 cctgagcttg aagctaccct cgttgctaaa atgtggtaaa tggtatgttt taactggaaa
     8641 agagtggatt tgccattctg atttagagtt atcagcattt gaatgggaat ttttacaatc
     8701 actcgatgta gaaatacgtg agactattca cttcgaggta aattatttgc ctttccaata
     8761 ataaaaagaa aggaattagt tgtgactatc gaattaaaaa acgagtatct tactgttcag
     8821 tttaaaacac ttggtggtca actgacttcg attaaagacg aggatgggat agagtatctc
     8881 tggcaagctg atccaaatta ttggaatgga caggcgccta ttctatttcc tatctgtggt
     8941 agtttacgaa atgattgggc tatttataga cctcaagaaa gacctttttt tacaggtctt
     9001 attcgtagac atggttttgt tcgaaaagaa gaatttattc tggaagaagt caatgataat
     9061 agcgtgacct ttagtattaa accaaatgct gagatgcttg ataattacct atatcagttt
     9121 gaactgagag ttgtttatac cttgaatggt aaatcaatta gaaccgaatt tcaggtaacg
     9181 aacttggaaa tggaaaaaac aatgccttac tttattggag cccatccagc attcaatagt
     9241 tctttagtag aaggtgaaaa ctatgaggat tattatattg aatttagtga ggttgagtct
     9301 tgctcgatac caaagagttt tcctgagaca ggattattag atttgcaaga tcggacacct
     9361 tttttggaaa atcaaaaaat tctcgatttg gactactcac ttttttccca tgatgccatt
     9421 acacttgacc agctcaagtc tcgtagcgta acgcttcggt caaggaagtc tggtaaaggt
     9481 cttcgagtag attttgatga ttttccgaac ttgattctgt ggtctacaac taataaaagt
     9541 ccattcattg ctttggaacc ttggagtggt ctctccactt cacttgaaga aggtaatttc
     9601 ttagaagata aaagacaggt aacgaaaatt tcacctcaag aaacttctag aaaaatctat
     9661 gatattacta tccttaatta aaatttgtta ttatttgagt cttcaataag atttgaatac
     9721 tcttaccttg tgatgataga ttggtcttct ccgtgccagt cttacatcgc aaggttttta
     9781 agttttttgt gggtctatgt caactgtagt gggtgacgaa aagctaatat ctaaagacag
     9841 tctggtagta aaaaataaga ttatttacta cttcttgatt taaaataata gtggagccat
     9901 taatttgtgg caaatttaat ttaatatttt gcctcaaatt agccacactt tttatagaac
     9961 taagaggaaa aatgaaattt tcttcctatt aatatagttg tttgaaatct taaatatagc
    10021 gt
//
LOCUS       DAXLPQ010000076         9662 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.078, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000076 DAXLPQ010000000
VERSION     DAXLPQ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.078"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            2..2374
                     /locus_tag="ACF3UO_002460"
     CDS             2..2374
                     /locus_tag="ACF3UO_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFD3658406.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTLTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2435..3895
                     /locus_tag="ACF3UO_002461"
     CDS             2435..3895
                     /locus_tag="ACF3UO_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3658407.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            3906..6110
                     /locus_tag="ACF3UO_002462"
     CDS             3906..6110
                     /locus_tag="ACF3UO_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFD3658408.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            6126..6275
                     /locus_tag="ACF3UO_002463"
     CDS             6126..6275
                     /locus_tag="ACF3UO_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658409.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6351..6944
                     /locus_tag="ACF3UO_002464"
     CDS             6351..6944
                     /locus_tag="ACF3UO_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFD3658410.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6957..7856
                     /locus_tag="ACF3UO_002465"
     CDS             6957..7856
                     /locus_tag="ACF3UO_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3658411.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7859..8344
                     /gene="ssb"
                     /locus_tag="ACF3UO_002466"
     CDS             7859..8344
                     /gene="ssb"
                     /locus_tag="ACF3UO_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD3658412.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(8485..8589)
                     /locus_tag="ACF3UO_002467"
     CDS             complement(8485..8589)
                     /locus_tag="ACF3UO_002467"
                     /inference="COORDINATES: protein motif:HMM:NF028245.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFD3658413.1"
                     /translation="MPVETALGLMISFGSLIATIIFGILAVVNNNQKK"
     gene            8763..9023
                     /locus_tag="ACF3UO_002468"
     CDS             8763..9023
                     /locus_tag="ACF3UO_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658414.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9460..>9662
                     /locus_tag="ACF3UO_002469"
     CDS             9460..>9662
                     /locus_tag="ACF3UO_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFD3658415.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
BASE COUNT         3640 a         1641 c         2012 g         2369 t
ORIGIN      
        1 catggcagaa gaaaaagaac cactagacaa tagtcgcttg ggaaaatcca aaagaaaatt
       61 agtacgattg caaaatgaat taaacgaaca aattgagaag atgtttgaac accagagaaa
      121 gaccaacggt cagccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga
      181 acgtttagaa aacaaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaggt
      241 agaaaaactt gaaagacaag aagagctaaa ggaaatgggc tataacaagt acggcggcct
      301 ggatatgaca atcgaaaata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg
      361 tgaatcgact ttttcagccg ctacgatccg aaaataccaa cggaaattgg aaacattaga
      421 acagctgaaa gaaagatcag aaaaaggaaa agaaaatctt cttcctgaag tacaagcaat
      481 tattgacagc ggacgagtga cgcaatggaa aaaaaatcca accatttatt ttttgaaaga
      541 ctatcgaaaa gttgctttag aactgaatga aaacggggga tttgaggaat caaaaaaata
      601 ccaagccacg tcggaagagg aaaaagcagc tgttcgtgaa ttacttgaag aggctgcgcc
      661 aactgattct ttgaaggaga aagaaaacga tcatttctat cgagtagaat tcaacgaaaa
      721 tgatccagaa aaaggattga aaagttatgg tggggagatc gtaacattag aattgatcga
      781 tcaactcaaa acgttggata accaatacgc cgcagaagca ggttattata aattctattt
      841 tgaagaagtg aagaacggag aagtagtcga tcagatccga atggatctag gggatggcgt
      901 caacagtaat caacccatct atttagagtt agcaaaattg tgcgaacaag tacctgaaaa
      961 ggaacaaaaa caaacggtca aaaatgaacc tgtttcgaaa gaacaaatgc agtcgaaaga
     1021 aacaaaaaca aaacaaaagg gctatcaaaa acgaacggca gaagagatta agcaagaagt
     1081 caaatccctt tcgcaacagg cactggatgc ggtgaaaaag catacccatt ctcctgaaga
     1141 cgtgaaagaa cttttgaatt ttatgtctcg ttttccagaa cgatccttta gaaatcaatt
     1201 attgattgag gaacaatttc caggtgcaac ggcttgttta ggtcgtgctg cgttgaaaaa
     1261 agaaggaatc tatatcaaaa aaggggaaca agggaacaag atctttgtca gaaaaacggt
     1321 caaaggattt tatgagaaag gacgtggctt tgttcgagaa acagaagcta caccagaaga
     1381 taaaaaacga atcgaaagtg gtcaaatcga agtgatcaaa aaaccttact acacgattga
     1441 aaaagtgttt gatatcacac aaacacagtt aaaacctgaa gactatccga aaatctttcc
     1501 gaaccgtgtc tttgattttc aattggataa aaaaggacag tcagaacttc aagctgggat
     1561 tcaagcggta gccaacaata ttggaataca aattcgagat atgacagaaa gtgaagtcta
     1621 tcaaagagaa ttaggacaag cacggggggc gtatgttcgt aacgaattta ctggcgaaga
     1681 agaaatcgtc atgaatactc gaaatactct tacgcagcat ttagctacaa gtattcatga
     1741 attagcccat gcaagaatgc acaaattttc agaattagat accgcaacta aagaattgca
     1801 ggcagaaatg acttcttata ttgtgtgcaa acattttgga atggacactt cggagaaagc
     1861 tattccttat attgcagcat ggacgaagaa tggtcagacg ttggatgata aggaagcggc
     1921 ggaacgtggg aaaatcatga atgatgtcag ccgtgtcgca aatgaattca ttcaaaccat
     1981 ttctaatgaa atcaatcaat acagagaaag agaaccagag atccaaccag cagaagtgaa
     2041 gcaggagcat aaaaatactg tagaaacggc agagaataag aatattgtgc ccgttggttc
     2101 actttggatc gacaagaaag acgggaaagt aatggaagaa gatacgggtc gaacgttaca
     2161 tttgaaggat gcggcgttta ttgaagatcc gcagcataat caagtgattt taaaaggaaa
     2221 aagttatgga aaagagattc aaacggcgtt accttcagaa gaatttgcgc taggaaatcc
     2281 attccgattt tcacttgaaa cagtgtcaga agtggccaaa cgaaaaaatg aaatctatta
     2341 tgaacaacaa ttgtcacaaa aagaacgcgt ataaaacaag taaaaaagac tatctgaaaa
     2401 acggatagtc ttttttcttt tgggaggttt gaaaatgacc gaaaaaaaaa tgagtcttat
     2461 tgatcgatgt aaacagatcg atatagtgga ttttgctcga aacaatggaa tggctgtagt
     2521 caataaagga cgagactatc gcttagaaga ccatgattca tttgtttttg atcgaagaaa
     2581 acaacgtttt tattggaaca gtcaaaatat tagtggcgac attattgaat tagctaaact
     2641 ttttttcata gacaaagaga tccaagactc taagcaacaa tttaaagcag ccacagattt
     2701 tattctaaag aatgaagaca aaacagaacg agtagaaaat cttcattttg agacagaaaa
     2761 gtacaaagat caccccgttg attatcaacc actcacagaa aaaggaagga attatctgaa
     2821 ggaagaacga aaactaccag agtggctgat tgattatgca gaaaaagaag ggttgattgc
     2881 cgaactaaag ccaaaacatg aacggcaaaa tttcttagtt cgagacgatc gtttagatca
     2941 tgcggtcgcc tttttatgga aagatccaca gacaaatgag acagtagggg cgagttatca
     3001 aggaacgttc attgattatg aacgttttgg tgagagaggc acatataagc atatagataa
     3061 aaattcgaca gcgaatcatg gctttaacct aaagatcggt gaccctaagc agttaaaatt
     3121 ttttgagagt agtattgatt tacttagcta tgctgcacta aatcgtgatc agttaaacga
     3181 tacgtggtta gtttcgatgg aagggttaaa acaccatgtg atcagtcatt attttggtga
     3241 ggcagtatct gaattgagaa agaaacaagc ctttcctcaa tccatcgaga tttgtgtgga
     3301 taatgaccgt gcaggacata ttttctacga aaaagaacaa ttaatgggcg cagttgatcc
     3361 atttacgaat cagaaagtac gttgtgaacg aggaatcgct aatgattggc aagtgccaaa
     3421 agaatacaaa gtcatttatg aagaagtcgc aaaagaagaa aagatcacac cagaagctat
     3481 tatggccata cacaagacag aaaacaatct gcaattaacg aaccaattgg tttccgctca
     3541 caaagtaaat gcgtcttttg gtcagcagct ttctgttaac gattcaatag aagctattaa
     3601 tttgaaagat atttgtagag aagtcgcaaa agaattaaaa gcttgtgaac gcgtggatgg
     3661 tacgtacgat tttgatcgtt tttatcaaga aaaaggggat attaatgctc agattctttt
     3721 ctcttataaa gcagaacaat actacaaagg ctataaaaat catgaacatg aatttgtacc
     3781 tgaagtaaaa aaggattgga atgatcaatt gaagcatgaa atctaccaac aagagatcag
     3841 aaagcaaaaa cgtgccatgt tgtttcaaca aggtagacag caagaaaggg agtgaaatcg
     3901 tcatgatgaa aaccgttatt ttagcagaaa aaccgtcaca agcgaaggct tatgccgata
     3961 gcttttctaa agctacccga aaagatgggt attttgagat ccaagatcga ttgttttcag
     4021 gagaaactgt gatcacgtat ggttttggtc atttagtcga gttagattcg cccgatatgt
     4081 acgatgaaaa ttggaaacaa tggtcattag agcatttgcc tattttccct acacattatc
     4141 actatcatgt tcctaaagat aagaaaaagc aattcaaggt ggtgaaacag caacttcaat
     4201 cggccgacac cattattatt gcgacagata gcgatcgtga aggggaactg atagcttgga
     4261 cgatcattca acaagcaggc gccgatcatg gaaagatatt taaaagactt tggatcaact
     4321 ccttagaaaa agaagccatt tatcagggat tccagcagtt acgagatgca gaagagacct
     4381 acccaaaatt tgaagaagca caagcacgcc agatcgccga ttggttgatc ggcatgaacg
     4441 gtagcccgct gtatagttta ctcttgcagc aaaaaggcat accaggaagt ttttccttag
     4501 gcagagtcca aaccccaacg ctttacatga tttatcaatt acaggaaaag attagaaact
     4561 tccaaaaaga accatatttt gaaggaaaag cccaagtaat cgctcaaaat ggcgcatttg
     4621 atgcgaagct tgatccgaat gaaacccaag cgacgcaaga agcatttgaa gattatttaa
     4681 aagaaaaggg ggttcaattg ggaaaacagc caggtacgat ccaccaagtt gaaaccgaga
     4741 aaaaaagtgc ggcaagtcca cgtctttttt ctctatccag ccttcaatct aaaatgaatc
     4801 agctcatgaa agctagtgcc aaagatactt tggaagccat gcaagggttg tatgaaggga
     4861 aatatctaag ctacccacga acagataccc cttatattac agaaggggag tatgcgtatc
     4921 tgttggatca cttagacgaa tacaaacact ttttaaaggc cgaagccatt cctactccta
     4981 ttcatacacc gaatagtcga tatgtgaata ataagaaagt ccaggaacat tacgcgatca
     5041 ttcctacaaa gacggtcatg acggcagcgg cttttgaaca attaagtcca ctgcagcagg
     5101 ctatttatga acaagtgtta aaaacaacgg tggccatgtt tgcggaaaag tatacctatg
     5161 aagaaacaac gatcttgacg caagttcagc agcttcagct aaagacagtc ggaaaagtac
     5221 cagtagatct aggttggaaa aagctgtttg gcaaagagag cgacagaaaa gaaaaggaag
     5281 aagaaccgct acttcctaaa gtgacaaaag gagaagcggt gacggtagat ctacaagtcc
     5341 ttgaaaaaga aacgaagcca ccacaacctt ataccgaagg tacgttgatc acagcgatga
     5401 aaacagctgg aaaaaccgtg gatagcgaag aagcacaatc catattgaaa gaagtagaag
     5461 gaatcggtac agaagcaaca cgagcaaata ttattgaaac tttgaaacaa aaggaatata
     5521 tcaaggtaga aaaaaataag cttgtggtga caaataaagg gattttactt tgccaagccg
     5581 tggaaaaaga gccgctgcta acaagtgccg aaatgaccgc caaatgggaa agttacttat
     5641 taaagattgg tgagcagaaa ggaacacaag ctactttctt agctaatatc caaaaatttg
     5701 tctctcactt gttggaagtc gtaccgggac aaatccagtc aacagatttt ggatcaacgt
     5761 tacaagaggt gaaagcagcc agtgaaaaac aggaagcaac gcgtcattta ggtgtttgtc
     5821 caaaatgtcg ggaacaagaa gtcttgcttt atcaaaatgt ggcggcatgt acgtctgaag
     5881 cctgtgattt taaattatgg acaacgattg ccaaaaagaa actcacagcc acacaactga
     5941 aagagatcat tcaaaacggc cgaacaagcc aatcagtcag aggactaaaa ggtcagaaag
     6001 gttcgtttga agcaacgatc gttttaaaag aagactttac aacaggcttt gaattttctg
     6061 aaaagaaaaa aacgaactat aagaaaagaa cacgccgcac tacaaaataa tgaaggggtt
     6121 atcctatgcg aaatacaaca cacaaacaac aagaaatcga aaatcaaaaa gcaaaaattc
     6181 gtttagaaca agagaaatta cgtgcaaata aaagaagact gcaacaatta aagaaccagc
     6241 agcgcattca aaaagaaatc gaattagatc gatagacgtt aatcttgtta caaataaact
     6301 actatgatat atttgatgta gtgtatttgt aacgaaggga ggggaagtaa atgcaagata
     6361 aactgaaaga attgttggct attcgcgatg gaaatttatc tatgaaggaa gccaggaaat
     6421 ttggaatcgc agcaaccact gtacaaagat tggtgaatca aggaaaattg atcaaagttg
     6481 atcgtggtta ttatgtagag gatggtcatg gaatagatga tttattttgg cttcagcaac
     6541 gattttccag gggaatcttc tctcatgaaa cgactttaga tatttaccag ctttctacga
     6601 atatgccgaa attcattcac ttaacttttc cccatggcta taacgttgat cgttcaatta
     6661 caaaagagca gcagttacaa tttcatttcg tgaagaaaga agtttatgaa ctaggaaaag
     6721 tagagggaac ttcctttcaa ggaaatccta ttactatgta tgataaagag cgtacacttt
     6781 gtgatatttg gaatccgaga tatgaatttg aatatgaaat gaaattagaa gcattaaaag
     6841 agtacatgga agacccattg agagatccaa gtaaattaag agattacatg acaaaactac
     6901 atgtagaaaa agaaatgaaa taccacatgc aaagcttata ttgatggagg aaaaagatga
     6961 caccgacaca atttgcagca aaaacaagaa atttagcaaa gagtacagga ttaaatgcac
     7021 agttagtgca acggcatttt atgatggatc gtctaattga acaaatttct gaatcaaagt
     7081 acaaaaatga cttcattttg aaaggcggct ttttattagg atcaaaatat ggaatcgata
     7141 gaaggacaac aattgatatc gatacgacat ttagaaatag caaattaact gaagaaaaat
     7201 tgaagagcat ttttaatgat ttaactagaa aacccacaaa agaaggcatt gttttctcta
     7261 ttcaaggaat gaaggaaaca agagaagccg atttttatcc tggatttcaa attaaattgg
     7321 tggctaattt agagaaagta cgtgtaccgt ttaaaatgga cgtgacaaca ggagattcta
     7381 tttatcctga agtagataca cactatcacc aattaatgtt tgaagataaa aaagtggaga
     7441 ttccagctta tccaacagaa caaattattg cagaaaagct aagtgctacg ttcagctttg
     7501 gcacagataa ttcgagagca aaagattact acgacttatt taccattccg aaactagaaa
     7561 atatcgatac gaaagagtta tacaaaagtg ttcgaaatac atttacaaaa cgtggggata
     7621 caaaaccgtt gtccttttat tatgaaagag aaatggataa gatcagagga aatgactatt
     7681 tggaaaagca gtgggaaaaa tatcgctcag ttaacacgtt tgcgaattcc atttcattta
     7741 cagatacagt caacgaaatt gatcacctaa tgaaaagtgt gatcaaaatt gaaaatcaag
     7801 aaagaaaacg gcagtttaaa agatcacaac aaatgaatca agaaatggag agataaagat
     7861 gatcaataat gtaactttag taggacgctt aaccaaagat ccagatttac gttataccgc
     7921 gagtggtact gcagtagcga cttttaccct agctgtcaac cgaaatttca cgaatcaaaa
     7981 cggcaatcga gaagctgatt ttattaactg tgtgatttgg cgcaaaccag cagaaacgat
     8041 ggcgacatta gctaaaaagg gcagtttgat cggcgttgtt ggacggattc aaacccgaac
     8101 ctacgataac caacaaggac aacgtgtgta tgtgacagaa gttgtggccg ataatttcca
     8161 actattagaa agtaaagcag cgacagaaag ccgtgcgcac gctgatcaat cgtccagcag
     8221 tccaagccct accacctttg aacaacggga tgtagctacg cctaacaaca atggattgaa
     8281 cgcttcacaa aatccatttg gcggacaatc aatcgatatt agtgatgatg atttaccatt
     8341 ctgattgtaa aagatcaata aagttgttat aatggatacg aaaagaggag ttgcgctaac
     8401 aactccccta acagcaccgt ttaagacggt gaccagctta atattatttt tgaaaaataa
     8461 tcgtcgaccg gctaaagctg acggttattt tttttgattg ttgtttacaa ctgctaagat
     8521 tccaaaaatg attgttgcga tcaaagaacc gaaactaatc attaatccta gcgccgtttc
     8581 aacaggcaaa aggcttctcc tttctgtaag attttggaag tacgcacata cgcaccacct
     8641 cactttcaat cggatagcca ccgtcacaaa ctttactgtc ttgatcatta tagcatatct
     8701 aaaatcgaat aaaaattctc aattttagct gtttttgcta taattttagc gaggtgatcg
     8761 tgatgaacaa atatgttggt ttgcttgata aaatccgagt aataaaaaca caaccattat
     8821 tggttcgctt tactttacaa acaattcatg aatcgattaa ttgtgtagtt gcagatattg
     8881 aaattatcga taaattgtta attatggatg atggaaaata caatattgcc gtcacaggtc
     8941 atttcaataa acggaatcaa ttagtcattg aatcgatgca aattagaaac cccgatcatt
     9001 ttacgcgatc gatgggcata taaaagaaga gctgcagtcc taaatgagga ttgcagctct
     9061 ttttgtttta catagaaaca ggaaaagacc tttttaggaa gacacaagtg ccttctcaat
     9121 tgaaaaacct ttctctcact ccaaccgcca ccgccgttcg agaagaaagg aagtgaacgt
     9181 tgcacgttca ctaagatatg gtgtcttgca aagcaagaca aaatagaaaa aacttcctct
     9241 caccaaaagg ttcgttcctg ttcgctatct ctttattgat ttgccagacc ggcaacaagt
     9301 tgccttttat caccaaaaag cgacaaggac aagggtaaat ggcacgctgc gcgcccttgt
     9361 ccttgtcgct tttcgttgat tcattctggc caacaaatca ataaagaaag aactaacgaa
     9421 aggaaataaa acctttccta agaggaggca gaatcaatca tgcgaaagaa atttgattat
     9481 tggggtgttc ccttcagcga attattccca aactatcatg caccacatac tgtcgaatgc
     9541 gattgtggag aaagagcgaa atgtatcaaa agctatcgtt tgtatcaatg tccaacatgc
     9601 gggaaaaaat ataccttgtc ttatggcgat tatgttttga ttgatgagaa agtaaagaaa
     9661 cg
//
LOCUS       DAXLPQ010000077         9479 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.079, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000077 DAXLPQ010000000
VERSION     DAXLPQ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.079"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            236..1042
                     /locus_tag="ACF3UO_002470"
     CDS             236..1042
                     /locus_tag="ACF3UO_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3658416.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1054..2274
                     /locus_tag="ACF3UO_002471"
     CDS             1054..2274
                     /locus_tag="ACF3UO_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3658417.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     NKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2264..3850
                     /locus_tag="ACF3UO_002472"
     CDS             2264..3850
                     /locus_tag="ACF3UO_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3658418.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVVQTSIAQPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSEAT
                     ERMVFRFAQQPSFIEFSAEAAGEKLIFIDSNAVVKTVNDCYLFDGKEIPEFALTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENQHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKKTSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSRDEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3889..6027
                     /locus_tag="ACF3UO_002473"
     CDS             3889..6027
                     /locus_tag="ACF3UO_002473"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3658419.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKIRLSGKMRGKAILDFQTAKHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKTIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNIHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKKLGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            6315..7706
                     /locus_tag="ACF3UO_002474"
     CDS             6315..7706
                     /locus_tag="ACF3UO_002474"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFD3658420.1"
                     /translation="MNKNGEWNAARRIFIIIMDVLVLNVSIYLSFLLKFQGEVPARNL
                     ETFQHSAVFISIIFIALNILLGAYVFYSRVISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVIVLSFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVVIDKYYENTKKLIDDIDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFKIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSVTAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENIRS
                     LAEIDFSQEKIYR"
     gene            7765..8574
                     /locus_tag="ACF3UO_002475"
     CDS             7765..8574
                     /locus_tag="ACF3UO_002475"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3658421.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFNHMTVMFD
                     KNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYARRGGSKYL
                     LPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN"
     gene            8546..>9479
                     /locus_tag="ACF3UO_002476"
     CDS             8546..>9479
                     /locus_tag="ACF3UO_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3658422.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLKRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNCGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNYPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFL"
BASE COUNT         3280 a         1448 c         1905 g         2846 t
ORIGIN      
        1 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
       61 tagaacccct tttttggttt attgcaattg tctagcatct tctgtaaaat agaaacgtta
      121 gagaaaatct tgtatcatag aaaattaaga aagaaataag aacgcagctc ggtaccaaaa
      181 atatggtaaa atggcacttg actgtaattc actgaaatcg cttggaggaa cacaaatgtt
      241 taaagatttg tatttattta tgaaagacat ttatcagaat agaaaattac tgctacagtt
      301 ttcgatcaat gacttcaaat caagatatgc aggatcgttt ttaggaatct tatgggcgtt
      361 tatcaatccg ctatttactg tattgattta ttggctggta tttggtgttg gactgaaagc
      421 acaaatgatc gatgcaaaat acccatttat cgtatattta gttaccggga tgattccctg
      481 gttcttcttc tcagatgcat ttgcatcaac tacggttgtt tttcgggaat atacttattt
      541 agtaaagaaa gtcgtattca atattcgtat cttgcccacg acgaaaatcc tatccaatct
      601 gtacacccat ttattcttca ttctgattgg catagctgtc gcgcttataa atggtatata
      661 tccttcagca atgtctttac agctgattta ttatttattt tgcatgtgtg ctttcttgac
      721 aggattgact tggctgacgg catcgatcca accattttta cctgatatca tgcaattaat
      781 tacgatcgtg ctgcagttga tcatgtggac attaccgata ttatggagcc ctaatcagtt
      841 tgattcaggt cttgtaagca tattgaaatt aaatccgctg tactatgttg ttcaaggtta
      901 tcgtgagtca tttttaagtg aagcttggtt ctgggagcat ggaacatata ctttgtattt
      961 ctgggttttc acgttagtaa tgttcgtaat cggctctgca gtgttccgta gattgaaacc
     1021 acatttttca gatgtgctgt aaggagaata gctatgacag aatatgcaat tagactaaaa
     1081 gatatcacaa aatcttataa tatgtacgca aaaccttcgg atcgatttcg tgaagccctc
     1141 aatcctttta agaaatccta tcatgatgta ttttatgcgt tgaaaaacgt gaatgtagaa
     1201 ataaaaaaag gtgagatgat cggtttcgtg ggagaaaacg gatcgggaaa atctacaatg
     1261 ttgaaaatca ttacgggagt actgacacca acatccggca cgatggaaat cgaaggaaaa
     1321 atctcagctt tgctagaact aggatcagga ttcaatcctg agtattctgg ctatgaaaat
     1381 atctatttaa atggaatggt tctaggattt tcaagagaag aagtcgatga aatggtcgat
     1441 gatatcattg aatttgctga tattggcgac catatttatc aacctgtaaa aacctattca
     1501 agtgggatgt tcgttcgtct agcttttgct gtagcgatca atgtgaatcc tgatattttg
     1561 attgtggatg aagcattggc agtaggagat cttgaattcc aactgaaatg tatggaaaaa
     1621 tttacagaaa ttaagaactc gggaaaaacg attttattcg tttctcatga tattagttcg
     1681 attcgccgtt tttgtgatcg ttcctattgg ttgaaaaatg gagaagttgt cgaatatggt
     1741 gatacgatgg aagtaacgac gaattacgaa aactttttga agaaaaaatc agttaaaaca
     1801 gtagatcgaa ataaaaacca agtagaacgc ttcgcagctc cagatatcgt agacgtgacg
     1861 aaagccgaat tgttggataa aaataaaaat ccagtggata tgctggaaca aggagaaaaa
     1921 ctatacgtta aagtaaccta tgaagtaaaa gacgatacaa tcaaaaatcc agttttagga
     1981 attgctctgc gtacagtcga caatttttat gtgtgcggac tcaatactct actagatggt
     2041 atcaagatcc cttggaaaaa aggtgagaat atcttttatc tggagtatga aaagttaggt
     2101 ttgttagctg gtgaatatta ttttgacgtt gcggtctttg aagaaaatgc aacggttcct
     2161 ttggtataca agacaaaata catgaacttg tttgtcagcg gttcttatat cggagaaggc
     2221 atcgtggtct tagaccataa atgggaagaa gggactcata gcaatgaaat atgattttga
     2281 aatggaccta gatgaacaaa gcagtgtggg aaaaattgcc gcacagatca aaccaggaag
     2341 taaagtttta gagtttggtc ccggaaacgg tcgattaacg aaacatttga tcggagcaaa
     2401 acaatgtgaa gtgagcattg ttgagctaga taaggaatta ttcgattttg tcagcgaatt
     2461 tgcccaagat ggattttatg gagatatcga aagttttgaa tgggcaaact attatgctgg
     2521 acagacattt gattacgtct tgtttgcgga tgttttagaa catttagtag atcctggaaa
     2581 aacattgaag aaagtcagag aatttttgaa tgaagaagga gagatcctga ttacattccc
     2641 taacttagca cataattctg tcatgatcga tttgttcaat aatcaattgc cttgggcttc
     2701 ttatggtctc ctagatgaaa cccataattc tttttatact catgatggtt tccaaaaagt
     2761 ttttgaaaaa gccggattat tcattaatat tgaagattac ttgtacttgg ctgtaggaga
     2821 tacagaatta aaatcaactt atgaagagtt gccggaagct gtacgctatg atttcaaaat
     2881 gcgaccattt ggtgaagtct accaatactt tttctcattg atgaaacatc cagtagtaca
     2941 aacttccatt gcacagccac aaaactctaa ttatgtaaaa gtactagaag taacccagca
     3001 aacgaaacaa gatgaaacaa tccaacaaat accattcaat aatttcacag gggaaaatga
     3061 gacactaagt ttccccgtgt cagaagcaac agaaagaatg gtgtttcgct tcgcacagca
     3121 acctagcttt atcgaattca gtgcagaagc tgctggagaa aaactcatat ttatcgattc
     3181 aaatgctgta gtcaaaacag taaatgattg ttatttgttt gatgggaaag aaataccaga
     3241 gttcgctcta acggatattt ctgggaaaga agtgactatc cattgtcact atcgctttat
     3301 cggggaattg acaccaacaa tgaaagaatt gctggaaaca attcgtccta tggctgaagt
     3361 cacaaagcag ctttctgaga aaaatgatga attagaaaga gaaaatcagc atcttcttga
     3421 ggaaaataca agactagacc atacgttaaa aacaaccaca aatcgctatt gcacattgtt
     3481 ggaaagtgat gaatggacga tcaaacatag actaggacga cgtaagaaaa aaacatcgaa
     3541 aaaaatacaa gaaaaagagc tttctatatg tattgatgag aaaatatggg atgcagaaac
     3601 aaaaatatta aaaatcatcg gatggggaat cgctaattcg gatcgccagc cattgtccta
     3661 taagttatca gctgaccaat cgccattttt cgaagcaatt cctgtttcac gagatgaagt
     3721 caatcaagca gaacagctcg caaaaggaac agaagcggga tttgaattac gaatcctttg
     3781 cgagcaagaa cgttcattct tagtggaagc agtagctcaa aatggtcaat catggatcat
     3841 tgaaatgtaa ataatgatta acttataaag ataaggagta aacgaatcgt gcaaaaaaaa
     3901 gaaattgccg tatttatcga tcaaatcact cgtgaacggg ccactggcga tttgcttatt
     3961 gtgggctggg caattgatga agtgaccaaa gaaatcccta cgataaaggt agaaaaagaa
     4021 aatgtgattg ctgaagcaac acatgtcgta agattggata tcaatcattt atataatctt
     4081 gatgttaaga cccaaagcgg ttttaagata cgtttatccg ggaaaatgag aggaaaagcg
     4141 atcttagatt ttcaaacggc aaaacatcaa aatggcatag ctgtgaaact aaatggtaaa
     4201 tacccttatg atgacggcat tgaatcttca tgggaaagaa aaaaaagatt actgaaaaaa
     4261 gggataaatt atgcaaggac tcatggcgta aaaaaaacaa tccgccgggt caaactggaa
     4321 ttgaaaccag gatcgatcga ctatgcagag tggatcagtc gtcacgagaa acctgatctg
     4381 aaagagcaaa ggaaagaagc acaagggttt gcataccgtc cattgatttc catacttatg
     4441 cctgtctata acgttgaaat caaatggctc gaaaaatgca ttgattcggt attggatcaa
     4501 acgtatgatc actgggaact atgtatcagt gatgatgctt ctactgatcc agctatccga
     4561 aagtgtctgg aatcctatca agcaaaggat gatagaatca aagttgtttt ccgacaagaa
     4621 aatggacata tcagtctggc aactaattct gcgttggaaa tggcagaagg agaatttata
     4681 gcgctcttag ataatgatga tgaattaccg ccatttgcat tatatgaagt ggcaaaagtg
     4741 ctaaacatac atccagaact ggatttgatc tacagtgacg aagataaaat cgatgcagat
     4801 ggcaatcgct ttgatccgca cttcaaagca gactggtctc ccgatacatt gatgggaaat
     4861 aattatatct ctcacttagg cgtatatcga acaagtattg tgaaaaagct tggcggtttc
     4921 cgtaaaggct acgaaggctc tcaagattat gatttggtcc ttcgtgtgac agaacaaatc
     4981 cctgcagatc atatttacca tattgaccga gtcttgtatc attggcggac gatcccagga
     5041 tcaaccgcaa gtaatggtga agccaaaagt tatatctatg attctggagt gaaagcattg
     5101 acagatgccc tgtctagaag gaatatcaaa ggaagcgtac gtcctggcag aatttctgga
     5161 ttttatgaga ttgcttatga cgtcttgcaa gaggatttgg tcagcgtgat cattccaacg
     5221 aagaatggct atgaagatct aaaaacttgt gtggattcga ttatcgaaaa aacgtcttat
     5281 ccaaattatg aaatcattat tgcagataat ggaagtacag atcctaaaat gcaggaatta
     5341 tttgcagaat acaagcatca gctgaaagac cgatttatcg ttgaattaat tgacattcca
     5401 ttcaattatt cacgtatcaa caatctggca gcagaaaaag caaacggcaa atacttttta
     5461 ttcttgaata acgatacaga agtgattgaa cctgactgga tgacagcgat ggtttcttat
     5521 gcacagtttg atcgaatcgg ctgtgtagga gcaaaactgt tttatccaga tgatacaacg
     5581 cagcatgcag gagtattatt aggaatcggt ggtgttgcag gacatgcatt gaataactat
     5641 gatcgaacac attgtggtta tttcggccga ttggtcattg acgtcaatta cttagcagtc
     5701 actgcagctt gtatgatggt caaggcagct gacttcaatg ctgtcaatgg atttgatgaa
     5761 acattagaag tagcattcaa tgatgttgac ttgtgtttga aagtttatga actgggtcgt
     5821 tacaatgtct atgcacatca agcagaattg tatcatttcg aatctaaatc aagaggttat
     5881 gaagatacac cagaaaaaca aagacgtttt gccggggaaa taaaaaaaat gcaagataag
     5941 tggccttctt atattgctca tgacccattt tataacgata atctaactaa agaaggaatc
     6001 ggcgattttt cattgagacc tgattgatta aaagaactgt attttcattt ttattgatga
     6061 aaatacagtt tttttagtat atgaaaattg taacttgtga ccgaagagat gataggaaga
     6121 acacccattc agtaggaaga atgtgatacg atttttgtcc aactctctgt taggcagaaa
     6181 tatacatata aacatacaat agtcaccttt tctagtttct tttaatttat tttacaattt
     6241 ggttattcac taggttttta aactttgcta tggtaagatg atagaggcat tattttatgg
     6301 ttaggagtgt atatatgaat aaaaatgggg agtggaatgc ggcacgtagg atattcatta
     6361 tcatcatgga tgtacttgta ttgaatgtgt cgatctatct tagctttttg ctgaagttcc
     6421 aaggagaagt cccagcaaga aacttagaga cctttcagca ttcagcagtt tttatttcca
     6481 ttatctttat tgcgttgaat attttgttag gagcttatgt attctatagc cgagtgatca
     6541 gtgatatcgt cttcattact gttattggac aggtgctgat agcattgggg atcatggtag
     6601 ttacttttgc tggacgttgg tttgcatttc cgcgtggcgt catcgtgctc tcgtttatac
     6661 ttggcacgat attacttagc gtttatcgga tagttgttta taaactatac ttaagagtca
     6721 gtcgtgataa gaaagtcctt atcgtaggtt tggagaaaga tgtcgcacca gctatccaaa
     6781 actttcaatc taagaaaaac aacaaacata aagttgaagc agtagtgatc gacaagtatt
     6841 acgaaaacac aaaaaaattg attgatgata tcgatattgt ctacttggct tctaaaatcc
     6901 cagaagacga aaaaatcaat atttatcaat tagtaactaa aaaagagaag aagctatttt
     6961 taaatacaac ttttgaaaat ttaacgatga tcaatccgaa catcatgaat ttcgaagatg
     7021 aaagtatcat tgaagcttcc ggtttcaaaa ttcagccgga atatgaatta ttcaaacgtc
     7081 tttttgatat catcgtttcg cttattttac tgattcttgc ttcacctttt atgctaatca
     7141 cagcgatttt ggtaaaaaca acttcacctg gaccaattat ttataaacaa gtacgtatta
     7201 cgaaaaatca aaaggaattt tcaatctata aatttcgttc catgagtgta acagctgaag
     7261 caaaatcagg accggtcttg gcaaagagca atgatgcacg tgtgacacca gtaggcaaat
     7321 ttatccgtgc cgtacgtttt gacgaattac ctcaaatctt taatgtattg aaaggcgata
     7381 tgtcgatcgt cggaccacgt ccagaaagac catttttcgt tgatcagttc aatgaagaaa
     7441 atccttatta ttatttaaga cacaatgtac gtgcagggat taccggatat gcacaagtat
     7501 acggaaaata tgtatcagat tataatagta aactacgttt tgatttgttg tatatcaaaa
     7561 agtattcctt actattagat ttgaagattt tacttcaaac aatcaaaatc ttatttgata
     7621 agatgtcctc acaaggacta gatgaagatg aaaatatccg ttcgttagca gaaatcgact
     7681 tttcacaaga gaaaatttat cgctagatgg gaaaaatttt gagcaaagaa gtaggagaga
     7741 acattggaaa ataaaaatat aagtatgctg ctttctttat atgataaaga aaaaccagag
     7801 tatttaaagg aagcattaac tagtattttt gagcaaacag taatgccaaa agaaattgta
     7861 ttagtttatg acggccctat aaatgaaaaa cttcaagtag ttgtcactta tttccaacaa
     7921 aaagatcctc acttgtttac agttgtaaaa ttagaaaaaa atcaaggatt ggggattgct
     7981 ttagcaattg gattagaaca tacgaaaaat cgcttagtag ccagaatgga tacagatgat
     8041 atcatggaac cccaacgatt agaaaaacaa ttagagatct tccaaaaaga tccagaaata
     8101 gcgattgttg ggagtaatat tgaggaattt actggcacgc ttagcaatgt tatcggaaga
     8161 aggattgtac ctgaatataa tgatgaaatc cgtgtgtttt cgaaaagaag aaatcccttt
     8221 aatcatatga cagtcatgtt tgataaaaat gctattttag aagtgggaaa ctatcgccca
     8281 ttaattggat ttgaagatta ttatttgtgg gtaagactgt tgaaggcggg atataaaggg
     8341 tataatatcc aagagattct agtccatgct agagcaggtg ctgacatgta tgctagacgt
     8401 ggaggaagta aatatctttt accaggaatt aaaggccgat atcgcgtatg gaaagatggt
     8461 ctaggatcac taaaagattt tctgatagtt atttgcggac atcttgtaat tagtttatta
     8521 ccgaataaaa ttaggggaaa agtatatgaa tcaaaactta gaaaaacaaa ctaaactttc
     8581 tataatcata cctttttaca atgcaaaaaa tactttaaaa agagctgtag acagcgtctt
     8641 aacgcaaggt tatcccaata ttgaaatctt gttaattgat gatggatcta cagatggtag
     8701 tagtgacatt ggtgacgaaa ttgctaatct agagagtaaa gtagcatgtt atcacttgga
     8761 aaacgctggt ccatcagttg ctaggaattg tgggataaaa gaagcaactg gaaatttggt
     8821 aggattttta gatagtgacg attatttttt acctgattgt tttaataatg ttttgaaaga
     8881 ctaccatagg aattaccccg atatcattgc ttttggatta agtaaaggaa aaaatataga
     8941 aaatgcaaat ttatttgttc ccgaaaagaa gattggttgt tcaagtgaag aagcaattga
     9001 gcaaatgttt agaagtaagg cagtggattt ttacgtatgg aataaatttt ttaaaaggga
     9061 attattcaat catatagttt ttccagaaaa taaattatat gaggatatgg ttcctatgta
     9121 tgaagctttt agagcggcta gtaaaattga tattttgcca ttttcaggta ttttttatta
     9181 tcaaaataat gatagcatcg tttatcagtc ttttaattca aaacagtatg ataatatttt
     9241 gcaaagaaaa atattagttg atgaagtaaa gaaagattat cctcgactta ttaatttggc
     9301 caatgctcga ttagtagacg gatacctttc aacagggttt aaaattactg gcaagaatca
     9361 aaatcagaaa gaaaagcaaa aatattataa tcagtctaaa agagaaataa aaagtatata
     9421 ttcaaaaata agaagtaaca atgagatatc aattgctaaa aaattagctt tatttttat
//
LOCUS       DAXLPQ010000078         8944 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.080, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000078 DAXLPQ010000000
VERSION     DAXLPQ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.080"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(15..1154)
                     /locus_tag="ACF3UO_002477"
     CDS             complement(15..1154)
                     /locus_tag="ACF3UO_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFD3658423.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACF3UO_002478"
     CDS             complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACF3UO_002478"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFD3658424.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACF3UO_002479"
     CDS             complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACF3UO_002479"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFD3658425.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACF3UO_002480"
     CDS             complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACF3UO_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFD3658426.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACF3UO_002481"
     CDS             complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACF3UO_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFD3658427.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6168..7259)
                     /locus_tag="ACF3UO_002482"
     CDS             complement(6168..7259)
                     /locus_tag="ACF3UO_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFD3658428.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACF3UO_002483"
     CDS             complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACF3UO_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFD3658429.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8802..8873
                     /locus_tag="ACF3UO_002484"
     tRNA            8802..8873
                     /locus_tag="ACF3UO_002484"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8835..8837,aa:Arg,seq:ccg)
BASE COUNT         2318 a         1897 c         1648 g         3081 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgcccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga tatttcagca agtagagagt tcgattactt aactaagtga
     1501 tcatactcga ctatctttca atagtcgatc atgtatcttc attagaaaag aattatttgt
     1561 tttttaagtt gtagaaagat ttcaaacctt tgtattctgc aacttcacca agttggtctt
     1621 cgatacgtag taattggttg tatttagcaa tacggtcagt acgtgataga gaaccagttt
     1681 tgatttggcc agcgtttgtt gcaacagcga tatcagagat tgttgaatct tctgtttcac
     1741 cagaacggtg agatacaact gctgtgtagc cagcttcttt agccatttcg atagcttcga
     1801 aagtttctgt taatgtaccg atttggttca ctttgataag gattgagtta gcaattcctt
     1861 tttcgatacc ttcagataat ttttgagtgt ttgttacgaa caagtcgtca ccaactaatt
     1921 gaactttgtc gcctaatacg tcagttaatt tcttgaatcc gtcccagtcg ttttcgtcta
     1981 atccatcttc gattgagatg attggatatt tagaaactaa ttcttcgtag aatttgatca
     2041 tttcgtcagt tgttttttcg ccttcgcctg agtcagctag tacgtaaaca cctttttctt
     2101 tgtcgtagaa ttctgaagaa gcagcatcca tagcaagaac aacgtcttta ccaggtacat
     2161 agccagcttt ttcgattgct tcgatgatta cttcaaaacc ttcttcgttt gaaccaaggt
     2221 ttggagcaaa tccaccttcg tcaccaacag aagttgctaa tccgcgagct ttcaagattg
     2281 aagctaatgc gtggaatact tcagcaccca tacgtagagc ttctttgaat gttggagcgc
     2341 caacaggcat gatcatgaat tcttggaagt cgattgagtt atcagcatgt gatccgccgt
     2401 tgatgatgtt catcattggt gttggcaata cttttgtgtt gaatccgcct aggtagtggt
     2461 ataaaggtac ttctaggtag tcagcagctg cacgtgcaac agcgatagaa acacctaaaa
     2521 tagcgttcgc acctaattta cctttgttag gagttccgtc taaagcgatc atagctttgt
     2581 cgatagccat ttggtcacga acatcgtagc caatgattgc ttcagcaatg atgttgttta
     2641 cgttgtcgac agctttagtt acacctttac cgccataacg agctttgtct ccgtcacgta
     2701 attcaactgc ttcgtattca ccagttgaag cacctgaagg aaccattccg cggccaaaag
     2761 ctccgctttc tgtgtatact tctacttcga ttgttgggtt accacgtgag tctaagatct
     2821 cgcgagcgta aacatcagta ataattgaca tgttttgtct ctcctttgag tttgtttttt
     2881 cctaagggat ttccctcata tacgatttta gttaattttg ctcattagtg caaacatttc
     2941 ttgcattttt cgcaaatttt caacaattat tttacagcgt ctaacaatga caagaatgaa
     3001 tctgcttgca agcttgcgcc accgactaaa gcaccgtcaa cattttcttt tgccatgtat
     3061 tcagcaatat tttctggttt tacagaaccg ccgtattgga tacgaactgc ttctgatact
     3121 tcttttccat aaagtttttc aactgtttga cgtacaactc cacaaatttc gtcagcgatt
     3181 tgtgcgtcag ctgatttacc agtaccgatt gcccagattg gttcataagc aataaccatg
     3241 tttgacacct gttcagctga aagatcagct aaaccagctg taatttgtcc ttcgatccat
     3301 tcagcagttt tgcctgcttc ataggtttct aaagattcgc cgcagcatag gattggtgtc
     3361 ataccatttg caaagatagc tttcgctttt ttattgatgt cttcgtctgt ttcatggaaa
     3421 tattcacgac gttctgaatg tccgatgatc acataatgaa cacctagatc agcaagagct
     3481 gctggtgaag tttcaccagt gaacgcacct gagttttccc agtagcagtt ttgtgctgag
     3541 atttttagtt ctgtaccttc agctgatgtc attaattctt gtaagaataa tgcaggagat
     3601 ccgatgactg aatcaacttt gtcatttgaa gggattttgt tttttactgc ttcagcaaat
     3661 tcttttgctt ctgatgcagt tttgttcatt ttccagttac ctgcgataat aggtttacgc
     3721 attgaggaac acactcctta atttattgaa aaatggctag ggagtcatga aaactccctt
     3781 caccttttgt tcgattactc gtcagaattg agcaaacttg gtcgtttatt tatcgttgat
     3841 tgctgctagt cctggtaatt ctttaccttc aagcaattcc aagcttgcgc cgccacctgt
     3901 tgagatgtgt gtgaatttgt cagcaaatcc taattgttct gctgctgcgg ctgagtctcc
     3961 gccaccgatg attgttgttg cgccttctaa gttagcgatt gcttcacaaa caccgattgt
     4021 acctttagca aagttactca tttcaaatac acccataggt ccgttccaaa caactgtttt
     4081 tgcaccttgt aatgtatcag caaataattt tactgatgct gggccgatgt ctaaagccat
     4141 caaaccatca ggaatgtctc cttcgattac ttgtgtttca acatcatttg aaaattctgg
     4201 tgcacagaca ttgtcgattg gcaagacaag tttgtcgcct gctttttcga ttaattcttt
     4261 tgctagttcc actttatcag cttctactag agagttaccg atcttgattc cttttgcttc
     4321 gtagaatgtg taagtcattc cgccaccgat caagatttta tctgctttag gaatcaagtt
     4381 ttcgattacg ccgattttat cagaaacttt tgcgccacca aggattgcaa tcattggtcg
     4441 ttttggttct tctactgctt caccgatgaa cttgatttct ttttccatca agaatccagc
     4501 aactgttggg ataccagttg aagcgatacc tacgttagaa gcatgtgcac ggtgagctgt
     4561 accgaaagca tcgttaacaa atacatcgcc taatgaagcc cagtatttac ctagttctgt
     4621 atcatttttg ctttcttttt taccgtcaat atcttcaaat cgtgtatttt cgaatacgac
     4681 aacgtcgccg tcattcatgt tgcggattgc ttcttctaat tgttctccgc gagtttcagg
     4741 tacgaatgtt acttctttac ctaataattc gcctagacgt tttgcaactg gagctaaaga
     4801 ttttccttct ttatcttctt ctgtttttac acgtccaagg tgagagaaaa ggattgcttt
     4861 tccgccttgt tctagaacgt agttgattgt tggcaatgct gctttgatac gagtgtcgtc
     4921 agtgatcacg ccgtctttca aaggaacgtt gaagtcaaca cggacaagaa cttttttgtc
     4981 ttttaaatcg atatctttca ctgttttctt agccatttta tttcctcctg aataaactta
     5041 ttatcaaaaa aagcggaaga agcgcgattg cttccccgct tttaaatgta catgtctata
     5101 atttacactt gtacgtttgt ctatcttata agttagcgaa gtattctaaa gtacgtacta
     5161 attgtgcagt gtatgacatt tcgttgtcgt accaagcaac agttttaact aattgtttgt
     5221 cgccaactgt cattacttta gtttgtgtag catcaaataa tgaaccgtaa gtcataccaa
     5281 cgatatctga agaaacgatt tcgtctgtgt tgtatccgta agattcgttt gaagcttctt
     5341 tcattgctgc attgatttcg tcaacagtta cttctttttc aagaactgtt actaattctg
     5401 ttaatgaacc tgttggtaca ggaacacgtt gagcagctcc gtctaattta ccgttcaatt
     5461 cgggaattac taaaccgata gctttagcag cacctgttga gttaggaacg atgtttgcag
     5521 cagcagcgcg tgcacggcgg aagtcacctt taggatgagg tccgtctaga gtcatttggt
     5581 cacctgtgta agcgtggata gttgtcatta atccttcaac aacaccaaat ttgtcgttca
     5641 atgttttagc cataggagct aaacagttag tagtacatga agcacctgag ataactgttt
     5701 ctttaccagt taatgtttcg tggtttgtgt tataaacgat tgttggaaca tcgtttccgc
     5761 caggagcaga gataacaacg cgtttagcac cagctgttaa atgtttttca gctgctgatt
     5821 tagaagtgaa gaaaccagta cattctagaa cgatatctac gcctagttcg ccccatggta
     5881 attcttctgg gttgcggtta gctaatactt taacttcttt tccgtttacg ttgaatgaac
     5941 cttcatgaac ttcaactgtt ccgttgaaac gtccttgagt tgtgtcgtat tttaacaagt
     6001 gtgccaacat tttagcatct gtcaagtcgt tgattgctac tacttcgatt ccatctacat
     6061 cttggatacg acggaatgct agacgtccaa tacgtccaaa accattaata cctactttaa
     6121 ctgtcattta agatttcctc cttatgaaaa tcaaaaaaat atttatttta aagggttacc
     6181 ccttttaaaa tctcatttgc agcagcttca tcagtgatga gccacgtttg ttttggtgca
     6241 tttttcatat aagctcgaat tgctttagct tttgattttc cgcccgcgat tgccatgatg
     6301 atcgggactt tttccaaatc ttgcaattct atgccgattc tagggacctt ataaacgact
     6361 tcaccttttt cattgaaaaa gtagccaaaa gattccgcaa cagcatttgc ttgtttcagc
     6421 atgactaatt ctttttcagt catcttacga cgtgctgcca tgtgtaatgc acgcccaata
     6481 ctatgaataa cacaattcgc ttcactaatc aagtttaaga cttcttggat agatggctca
     6541 ttgagtaaag aattgtaagt tgccagactt aattgttccg gaacataaag tgcgcggtgg
     6601 ttaccgtttg ctttagcagc cattcttgca ctgacagaat ttgcctgtac agttatcgct
     6661 tcaccaatcc cgcctcttgc agggacaaac aggttatgcc gtttcttatt ttccagatta
     6721 gacaattgtt cggctaccac agccatagta gttcctccca tcacagcgat gatattctcg
     6781 ccttctggaa gtagtcggtc taaggcttcg ctcagcgctt cgccgaatgc atcagccact
     6841 ttggtctgct cttcgctgtt tcctgaaaca acgatacagc gttggttacc aaaatattct
     6901 gccaactgtt gttcggtttg atgcgtacct aaaagctgat ccatgaagtt ttcaaggctt
     6961 tgataaactt cttcgccctt agttgtcagc gtcataccgc tttttgaggt gtcgatcaaa
     7021 ttcagatttt tcaaaaggtc tgtttctgtt cgtaagactc gttctgtgat ccccatactt
     7081 tccgataaac ttcgacgccc aatcggctgc atccaataga tatttcgtaa aattttatag
     7141 cgttcttgca acacttcgat aatatctggt gcaacagatt caatcatttt tatttcatcc
     7201 agcatagcga tctccttagt tggacacttt acgtccaatg tagacttaaa acgacccata
     7261 tacgataaaa aaagaaatta actattcgaa tttcacatca ataaagggaa atctcaacct
     7321 cacgactgta agtctaacag ttttgctctc gtttttcaac taaaaagact agaaaaagtg
     7381 aaatactttt tctagtcttt tgactgatta gttatcataa cgttttcttt ttgatgaact
     7441 cgggattcct aataaatcac gatattttgc tactgttcgt cttgagatcg ctatctcatc
     7501 ttttttcagc aattcaacca atttctggtc agacaacggc ttgtttttgt cttcttgatc
     7561 gactaattcc tgcagctttt tcttcgctgt atctgctgaa aggtcttctg tctgttctgt
     7621 actattcgta ggaattcgtg tagtgaaaaa tttttttaat tcaaatacac cgaagtctgt
     7681 ttccaaatat ttcccgttga ctgcacgact gaccgtggat tcatgcacat ctatctcagt
     7741 tgcaacttcc tttaacgtaa gaggcttgat tggacgttcc ttgtcgataa agaaagcttt
     7801 ttgccgggaa acaatgactt gagcaacccg caaaattgta tccccacgtt gtaggatcgt
     7861 tttcttcaac cattcgaatt cctgtttccg ttcttttaaa taattttcag tttctttatc
     7921 tgcttgttgt gacatttgtt tgaagtaact ctcttgaaag cgtatatttg gctgattttt
     7981 tcggtttgag ataacttgta catttttatc gtcgtccact aatacccgga catcaggaat
     8041 aatgtacaat tcgctgctac ggtcgaaaat ccggccaggg cttggactca acgtttgtaa
     8101 atagtcgaat atctgctgaa cagcatgtag atcaacagaa aaacgttgtg cgatttcttt
     8161 ccattttcgc tccaccagtt cctcaaaaca ttcttccaac acgatataag ctaattccgg
     8221 cgcataatca tctcgttctg tttgaagcat gagacattct tgcaaactac gtgcacctac
     8281 tccagctggt tctaattgct gaatcagagt caacgcatcg agcatttgga taggcgtagc
     8341 tccaatctct tttccggctt cttctaaact aatcgtcaaa aatccgttca aatcgatgta
     8401 ttctacaaga taaagaacga ttttcctcaa aaaagtatct cggtaattca aatggacttg
     8461 ttcgatcaat gaatcaaata aagacccttt tgtatcagga atctgattta ggtaatttgt
     8521 ctcttctcct tcataagaag atgaagaagc ttttatgtaa tctggctgcc attccggctc
     8581 aacaacttcc accaatggat tttccattgc ttgattctca acgaatgcca acagctcctc
     8641 actgttatat tgtaaaactt ggatggactg ttgcaactgt tgcgtcatgg ctagtttctg
     8701 tgtctgctgc tgtttttgtg aaaaattttg ctcaaatttc atttttttgt ccaatcccct
     8761 tgtaattttt tatctgttta gttacaatta tcccagtgct tgcgtcctta gtgtagtgga
     8821 tatcacgtaa gattccggtt cttgagacgg gggttcgatt ccctcaggac gcgttctact
     8881 gctattttag cataatttac gaatagttgc ttctttattt ttaagtgaaa actgtccgcc
     8941 aaag
//
LOCUS       DAXLPQ010000079         8888 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.081, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000079 DAXLPQ010000000
VERSION     DAXLPQ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.081"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(154..552)
                     /locus_tag="ACF3UO_002485"
     CDS             complement(154..552)
                     /locus_tag="ACF3UO_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFD3658430.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(549..1322)
                     /locus_tag="ACF3UO_002486"
     CDS             complement(549..1322)
                     /locus_tag="ACF3UO_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFD3658431.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1319..2002)
                     /locus_tag="ACF3UO_002487"
     CDS             complement(1319..2002)
                     /locus_tag="ACF3UO_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFD3658432.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2169..3056)
                     /locus_tag="ACF3UO_002488"
     CDS             complement(2169..3056)
                     /locus_tag="ACF3UO_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3658433.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3053..3922)
                     /locus_tag="ACF3UO_002489"
     CDS             complement(3053..3922)
                     /locus_tag="ACF3UO_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3658434.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4059..5345)
                     /locus_tag="ACF3UO_002490"
     CDS             complement(4059..5345)
                     /locus_tag="ACF3UO_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3658435.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5618..6196
                     /locus_tag="ACF3UO_002491"
     CDS             5618..6196
                     /locus_tag="ACF3UO_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3658436.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6196..7125
                     /locus_tag="ACF3UO_002492"
     CDS             6196..7125
                     /locus_tag="ACF3UO_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658437.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7122..8858
                     /locus_tag="ACF3UO_002493"
     CDS             7122..8858
                     /locus_tag="ACF3UO_002493"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3658438.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
BASE COUNT         2825 a         1881 c         1501 g         2681 t
ORIGIN      
        1 tagcatattt tgaaaagaaa gtctgatgct tagagtagaa tttcataaaa atttactatt
       61 tcataagtat tcacgagaaa aatacaaaca aaaaagcgga aataacgctc atccgccttc
      121 ttgtttgtgt ttatttcctc ttcaaacgct tgtctatgat tcagactttt ctctatcgtt
      181 attttcatct aaaagttctt gcattccgat aatttctcga tattgatgaa tcttagtgat
      241 accaatgact ttgtctacat caatactaaa acaaatacca ttacctggaa tatcgatgtt
      301 gatgccttga ccaatcgcat ccattacttt attcgtcaaa ctatcgggta ctaatgtcaa
      361 cacaatatct ttttctggcg aaatgtccaa acctaaaaat ttccctgaat catgtacacc
      421 agaacctctt ccatgtaaga tcgttccgcc tgctgcacct gcttcttttg aaaagtcgat
      481 aacatcttcg cccattcctc cgtcaacgat cgtcacaatc atgtgaagat tcaatgctac
      541 aagatctttc atttgctttc ccccaatttt tgcaatcttt ctttttcgat tctgtctttt
      601 tcatcttttc gtttataaat atatcctagt actaaagtgg ataatattgg tgtcaatgca
      661 atcattgcaa ccacaccaaa cccgtcaatg atcggatctc ttccttcaat ttgtgcagcg
      721 attgccacgc tcattgataa aataaatgtc gaacacatcg ggcccgttgc tactccaccg
      781 ttatcaaaag ccattgctaa aaagatcttg tccacttttc gtcctaaaat aaatgctagc
      841 ccgtatcctg ggatcaagaa ataataaaga gagaatccga cgagcaaacg ccacatagac
      901 aatcctactg ctgcgccgat cccaattgaa attaccatca gcatgatttt cgatcggatt
      961 ctcccctcgc tcaattcttc aacctgtttg atcattacat gaatcgccgg ctcagcaaac
     1021 cctactaaga accccattaa aaagccaagg ggaaccagta tataattgta aggcaatccc
     1081 gcaatagcac tgcctaaatg ctgtcctacc ggtacataag ccatattgac tccgtgcagg
     1141 aaaaggatca acccaatagt cgttatcaag aaacctttca taatgtcaaa gaaacgcttt
     1201 ttgcgcatac gaaaactaat gatattcatt aaaacaaata ggattacgat aggtgccact
     1261 gccaaaatga cttccatggt aacgatttcg attccatcta tcacttgctg ccagaaactc
     1321 attggaagat cacccccaaa atcatcacgg caagaatcgg ccctaacgaa gcaataccga
     1381 ccattccaaa actgtcattt tcatttttct tttgtttgat catactagtc atccctccgg
     1441 caagggccaa gataaatgga acagttactg gaccagtagt cactcccccc gaatcaaaag
     1501 caatcggcat aaattcggaa ctggtgaaaa atgaggcgat caaaacgcct atgtagccta
     1561 tagccatcaa ttgataatag gatagcttga atacgacccg aagcagcgca aaggctagaa
     1621 atactccagt gccgacgctg acgatcccaa tcagcaacac tctgccaatc tctccgtcag
     1681 atatatcata tacttgttgt cccaaaactt gcacggaagg ttcagcaatc gtgatcacga
     1741 tcccgatagc aaatcccaaa ctgaccaaaa cggtcaaact tttctttttg atcatatatt
     1801 tccctactag atctccgact tccatcatag aataatctgc tccaaacaaa aagagcgtca
     1861 ttccgatcat catgattgcc gcaccaacca gaaatgaagc gaggtcttct ccttctaacg
     1921 gtgcaaaaac aaacgttaaa atgacaatca ggacagtcat cggcaatata gcagcaatca
     1981 cttctttaaa attttttagc atgtatcctc ctcctttact ctttaagttt accttaaaat
     2041 gaaagagttt tcgagcacaa acttaaaacg ttatcattta atttttctca acataaaata
     2101 acacacgtcc caaaagtatc tttttacttg gaaaaatgac tttgaaggaa cgcgcttatt
     2161 gtgttttttt attttacaga gccgatcatt ccttgaacga attgcttttg caaaacaaaa
     2221 aatacgatgg cagttggtaa agtagcgatg actaatccag ccatgatcat tccatagtct
     2281 ggtgtatagg aagcacccat agcagataaa acaagcggaa ccgtccgttt atcaggagat
     2341 tgcaaagcta ctaagggcca taaataattg ttccagctac tcatgaatgt gatgattgca
     2401 gccgcggcat aggtattttt agccgtcggc atatacactc taaaaaaaat acttagttct
     2461 tttagaccgt ctaatcgagc ggcttctact agatcttttg gaaaagattt aacattttgt
     2521 cgaaagaaga agatcaaaaa agcagtgcta acagatggca ggatgacaac caagaaactg
     2581 ttgattccca aaaccgttcc gttcaattgt gaaaacattc gatataaagg gatcatcaat
     2641 gccgcaaaag gaaccatcat cgatagcagt agaatattga aaattaggtc ttttcgttta
     2701 ctttgataaa tctcaaatcc atatcctgcc attgacgaaa tcagcaatgc aaacacagtg
     2761 gtcaccaaag cgatcatcgc tgaattccaa agggaacgag taaaattcag ctcattggaa
     2821 aacaaatttt gaaaattgat gatcaagtta ctgccaatct ttatttttcc cgatgtgata
     2881 tccacgggtg tattcgtcat tcccaaaacc atccagacaa aagggaaaat ggaaataaat
     2941 gataggatgc ttaatgctgt atactttaat actgacccaa ttgtcgaacg aagttctaat
     3001 gcttgttttt tgacgttggg gcgttcgatt gtttcttttt ctaccatatt tttcatcgac
     3061 tttctcctcc tactttcgtt tggattatcg acaatatcac aataaaggaa acaataacaa
     3121 aggaaactgc tgccgcatat ccaaaattag gcgtgaattt ataactcaaa ttatagatgt
     3181 attgagatag ggtggtcgtt gcatttgctg gtcccccgcc agtaatattt tgtacttcat
     3241 caaaaagctg caatgtcccg atcgtcgaag taatggaagt aaacaaaatg attggtttta
     3301 aatttgggat cgtcactttg ataaactgct gccatttaga agcaccgtca atagatgctg
     3361 cttcataaat ctccgaatca atattttgca tgcctgaaag gaaaaaaatc atattgtatc
     3421 cagtccaacg ccaagtgatc gaaagaatga tcagaactct cgcccaaatt ggatgagtca
     3481 accagccaat cggtgtgtca atcataccaa tgcccaacaa caagttgttt acaaggccag
     3541 attgagaaaa tagacttttc atgatcagag aataactgac catcgaagtg atacatggaa
     3601 gaaagatagc ggttcgaaac aaccctttat atttcaactt tttatcattt aaaaggttgg
     3661 aaataaaaag tgctagaaac aacatgatcg gtacttgtac aagtaaatac aggaatgtat
     3721 taaaaaaagc ttttttaaaa gttgcatctg tcaacatccg ctgataatta cctaacccgt
     3781 taaatgtcat attgacaggg ggaccacttt gaaaagacgt gatcaaagcc aaaaccatcg
     3841 gaataaaaac catgattgat atcaaaatga ctggcaagat taaaaaagca tgcccgtttt
     3901 tgaataaatc tttctgcttc attcttttcc ctccaattct atcattgatt atctacatga
     3961 aaagacaaga aagacaatat ctgtaaggca gacgtgatct tttttgtctt ttcgtttgtc
     4021 tgatgaaaaa gcgaagaaat tcactttttt accaccgatc aattagccaa ttgtgcttct
     4081 acttgttttt gtgtatctgc tagtaccttg tctgtctctt ctccattgat gattcgatga
     4141 agagcttcag ctacgactgc ttcaattgca taggtctcat gtccgtaatt cacttctggt
     4201 atttcagatg tccatgttga aaaatcgtca aagatctttt gaccactgta aaattcagaa
     4261 gcttcttgat aagcttcttg ttcattcgcg ctaagcatcg tagatactag tccgatttct
     4321 ttcgcaagag tgcccatcag ttcttcattc gaagcaaacg ttgcttctag gaaatctttc
     4381 gctgaatctt ctccagctac tcctttgatc acataccagc cagcgccgcc aaggttagaa
     4441 gcttgcgctt tttgcagatt ttctggaagt gcaggtattg gtgcaatctt ccattttcca
     4501 gattggtttt ctgctccttg gatcgttgaa gaataccaag cgccagttgg gctagaagct
     4561 actgctcctg attgtatcgc agttactcca gcattccagt cagaggtttg ttcgactaga
     4621 tcttctttca aaagagtggc aaacaattca agaccatact ttaaagatgc attgtcttgg
     4681 atcgtgactg tctccccatc ttcagatgta taccattctc ctgcctgttg cataatcatc
     4741 cttactcgac caaggtcaga aggattgact tcagcgattt tctttcccgt cttttctttg
     4801 acatctcgcg ctacttgaat atactcgtcc cacttcagat tctccatatc ctcttctgta
     4861 taacctgctt ctgccatcag atccgtacga tagaagtttg ctgttacgcc cgaatcgaaa
     4921 ggaacaccgt atattttatc tcctactttg tttaccgcaa atttatacgg tgcaaaatga
     4981 tcttccttta caatagcaga caaattagcg aatgcatctg gataagaagt caaatagcct
     5041 tgtatcctat aatcttcaat caagacgata ttgggcaatc cttctgtatt cccgctcgct
     5101 aaagcggtgt tcagtttctg aacgatatca tcctgagaca tcgtaacaac ttctatctct
     5161 gtttcttcgt tctcataaac tttttttgct tcattcactg ctttgatatt gaatgtctca
     5221 tcccacgccc agacagtgac tttttcttct ttgtctgctg tactactagc acttccgcat
     5281 cctgttaaga aacctgatgc tgccgctaaa caaacgactc cagcaattaa ctttctgatg
     5341 ttcattttta tccgctcctt ttccatccat tagttgttta cgtttgctac attcatcata
     5401 ccaaaatttg aaaacggttt ctttattatt cagatacttc aaaaatttct cctaaaataa
     5461 taaaaaaata caaatcaact atgacaaaag gaataatctt agcatctaga ccaaagatcg
     5521 aaatggtgag gtttctttaa aataaaaata tccttgcatt ttctcctaga aataagtatt
     5581 tttaaattac aagactattc ttaaggcggg taaaaaaatg ccaatacgcg taattcttat
     5641 cgatgatgaa cagacgattt tagatggaat gaaacagttg atcaattggt ctgagcacgg
     5701 gtttcaatta atagggactt tttccagtcc gctgaaagcg cttgattttt ctttggtaca
     5761 tgcaatcgat atcgtggtca cagatgtaat gatgcctgaa ttaaatggaa tcgaattatc
     5821 gcggctatta aaacagcaac aacctgaaac acagatcctt atcctctcta gctatgatga
     5881 atttgatatg gttaaagatt cttttaaaga aggcgtcgct gattatcttt taaagcctcg
     5941 attgagtcct gatttttttc taaattcctt aactgccgtt tcacaaaaaa tcaaaaaaaa
     6001 gcccaacaaa agcccaatca ccaatcgtta tgagcagatc tgcgagaatc tttcacagca
     6061 gattgctgga caaactcgtc cattgcttga ccctcttctt tttgaacaca ccttgttttt
     6121 ctgttatata ccgaaaaacg gccattcagt tcaaaacaag gctctaaaca aaaacagtcg
     6181 atcacccatt cattgatgga tagcgacgat tcgtttacta tttatcctgt ttctaccttt
     6241 tcggaagaat ccggctatgt aatcaatact gattccaaag atacacttag gaagtttgtt
     6301 caaaagtttc gtcaagaagt ttttccaggt gatttttttg ttgtttctga ttcttttgca
     6361 atccaagata tcaatgaaat attccaagag atcagaaatt gcaccaaagg acaacgtttc
     6421 tatcataagg gaaagaacct tgcttatcag catgaacttc ttccgttatt aaccaaccac
     6481 gagcagcaag caagtagtta tttaacaaaa atcgttcata aagactacgc tttagctgtc
     6541 aaagaacttg agaatttctt cacgacgata ttggaacagc ctattgatcc agcttatttg
     6601 aaacatgagg caatcaatcg tttctatgca ttactcaacg ctttggctga cgagcatgtt
     6661 gggaatgaag aactttcttt gctcaagatc gcccttcctt ctttattagc cgatgctgag
     6721 tatttcgaag atttttctat tcttgtcaaa gaaacacttg agaaactcac ccacttttct
     6781 gcaaatgcaa aaaaagacaa tttcgatatc ttgactttga tctacgagtt cgtccaggaa
     6841 aattatgaga aagaaatcaa tttacaactt ttatccgaaa aatatcattt ttcatatagc
     6901 tatctctcag ccatctttac tgaaaaattt ggtatcaact tttcaaaata tctaaaaaaa
     6961 gtccgtatca gtaaagccaa gctctttttg acggaaacac ggcttacttt gacggaaatc
     7021 tgtgagaaag tcggctatac cgaactgggt tatttctcca gagtttttaa agaagagaca
     7081 ggaatgacac cttctcaata ccgtaaagga acttttgtaa aatgagaaaa aaaatcaaag
     7141 agcatgaact ctttgccaaa cttctgttca ttttgttcat cggtcttttt ctgcaagcca
     7201 tcgtcatttc tttgtttatt tatcatcgat caagggatgc ctatatccag ctgttcaatc
     7261 aatcgaatga tgtggtacta aaaaagattc aatctgaatt tgaaagtttg aatgatacaa
     7321 tcgagaatac attagccgct tttgattcta atccagctgt caaaagctat ttttccaatg
     7381 atccagccca acatatggaa cagcttcagc aactaagaac aatccaaaaa atgaatgact
     7441 ctctttcaaa aatccatcca atgatcgatt acgatgtatt gatctttgga gaaaatggaa
     7501 gaacttttgt cggaaacgac atgctcactg ccgtatctgc cgattctttt tttcaatctg
     7561 cgattgctca gagagtgaat gaacgtgctg ctgatacaca aatgcttttt gcacaccacg
     7621 gattgactct tcgcgataag aaagcaccca gcgtcttctt tgtcaaaaaa ctgaaaaata
     7681 cattgaatca cgtttacgga tatgctgttt tatcgatctc atccaagcaa ctagcgaatc
     7741 tttttcaatc tgtagtaaat cctgagatat cgaagatctc cttcatgaac gaagaacaga
     7801 cgatcatcgc atcaaatgaa gaaaatacaa ttgggagccg atcaatgatt ttcaaaaaac
     7861 taacagtagg tgaaacaacg atttcaaatg gacagcagtt gacccgtctt cctctgtacc
     7921 gccaggattg tacattactc agtcaagtcg atcttcattc tttatctaac caaatgggcg
     7981 tgatttttcc gattattttg tataatatcg tgacacttgc ttttgctggc tcattggtat
     8041 ttatgtattt ggatcgacac acaaaatcga tctaccgctt gattgattcg ctaaaacggc
     8101 tagaggaaga tggcttaaaa gctactgttc ctgtacaagg aagccatgaa gtccaattgc
     8161 tagggaatac gatcaatcaa ttgctaagta atgctcagca tcattatgaa cagacgatcc
     8221 aagacgaaaa gaagaaacgt tcgcttgaaa tccaaactat gcaagcacag atacagcccc
     8281 attttattta taatacgctg actagcttga aatttttgat ttggcagaaa aaaacagatg
     8341 aagcagttca aggaatcgac agtttcatta ctttactaag aagtacgatt gggaaaaaag
     8401 aagaagtgat tccagtcaag gaagaaatca aaagcgtaca aagttacatc gatcttttga
     8461 gtatgcgata tggcgaaaga atctcggcta aaataatgat tcctgatgaa ctgcagtcat
     8521 tatctatgcc gaatatgatc cttcaaccaa ttatcgaaaa cgcctatctt catgcttttc
     8581 acaataaaac gcaaggattc atcacggtgt acggcaaaac aaaaaatcag cttcttttat
     8641 tcgaagtgat tgataacggc gatggcttcg atactgaaaa taccaaacaa aaaaatgatc
     8701 atttttcagg aatcggcatc agccatgtag atgagcggat acgcctaatg tatggcgatg
     8761 catatggctt aacgatccaa tcagtgattg ggacaggaac gactgtaacg atttgtctac
     8821 cgcttcttcc taaaaatcaa tcagaatatc aaaaataaag aatagccaag cgctgatttt
     8881 tttatttt
//
LOCUS       DAXLPQ010000080         8586 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.082, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000080 DAXLPQ010000000
VERSION     DAXLPQ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.082"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(45..1511)
                     /locus_tag="ACF3UO_002494"
     CDS             complement(45..1511)
                     /locus_tag="ACF3UO_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFD3658439.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="ACF3UO_002495"
     CDS             1898..2494
                     /locus_tag="ACF3UO_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3658440.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="ACF3UO_002496"
     CDS             complement(2552..3034)
                     /locus_tag="ACF3UO_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658441.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="ACF3UO_002497"
     CDS             complement(3140..3337)
                     /locus_tag="ACF3UO_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658442.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3632..4390
                     /locus_tag="ACF3UO_002498"
     CDS             3632..4390
                     /locus_tag="ACF3UO_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFD3658443.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4450..4878
                     /locus_tag="ACF3UO_002499"
     CDS             4450..4878
                     /locus_tag="ACF3UO_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658444.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4924..4996
                     /locus_tag="ACF3UO_002500"
     tRNA            4924..4996
                     /locus_tag="ACF3UO_002500"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4957..4959,aa:Gln,seq:ctg)
     gene            complement(5146..5517)
                     /locus_tag="ACF3UO_002501"
     CDS             complement(5146..5517)
                     /locus_tag="ACF3UO_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3658445.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5732..5917
                     /locus_tag="ACF3UO_002502"
     CDS             5732..5917
                     /locus_tag="ACF3UO_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658446.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6000..6188)
                     /locus_tag="ACF3UO_002503"
     CDS             complement(6000..6188)
                     /locus_tag="ACF3UO_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658447.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6212..6475)
                     /locus_tag="ACF3UO_002504"
     CDS             complement(6212..6475)
                     /locus_tag="ACF3UO_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658448.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6633..6890
                     /locus_tag="ACF3UO_002505"
     CDS             6633..6890
                     /locus_tag="ACF3UO_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFD3658449.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6961..7152)
                     /locus_tag="ACF3UO_002506"
     CDS             complement(6961..7152)
                     /locus_tag="ACF3UO_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658450.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7293..7613)
                     /locus_tag="ACF3UO_002507"
     CDS             complement(7293..7613)
                     /locus_tag="ACF3UO_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658451.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7636..8070)
                     /locus_tag="ACF3UO_002508"
     CDS             complement(7636..8070)
                     /locus_tag="ACF3UO_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3658452.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8405..>8586
                     /locus_tag="ACF3UO_002509"
     CDS             8405..>8586
                     /locus_tag="ACF3UO_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3658453.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2718 a         1694 c         1362 g         2812 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctggggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta tttagaagaa tttttttcaa aaaattaaaa catattcctt aaaaactaat
     3541 tatttcctac atattaaaat ataatacttc catttccaat aaaaatacat ttataatagg
     3601 aaagataaac agctgaaaag ggagatttca aatgaagaaa aaaacgttca aaaaactatt
     3661 gtttctaggg ggcacagctg ctcttttatt aagcggtaca agttattacc tacatatcca
     3721 ttctccagaa catacaatga acactgcaca aaaaagttca acacaaaaaa cgaaaaagac
     3781 aaaagagaaa gcagaagttt tactagatgt tccattagag agccagtttg attctccttc
     3841 tttagaaaat ggctgtgaag tcacttcgct ttctatgctt ttatcttttt atggttatga
     3901 aacaactaaa aaccagttag ctgagcaatt ggattacgtc cctgttttca atgcagatgg
     3961 gactcatggc gatcctaatg aaggatttgt tggtgatatc agtggcggag actgggctat
     4021 ggtcgtctat gttcccccag ttgcctccct tgctcagcaa atcgtccaaa cggattatca
     4081 cacttttcca aaaaccgatg ctcaactcga tgatatcaaa aaagcactat ctaaaggaaa
     4141 tcctgtctgg acttctgtga ctatcaattt tgaagtccca gatgaaactg attttatgac
     4201 ttggaccaca aataatggag aagtaagagt cactcctctt gttcatgctt gtgtagtcac
     4261 tggatatgac aaagaaaata tttatgtcaa cgatccctat ggtgtaaaaa atcgagcagt
     4321 accgatcaac gatttttcgg cgattttcac tgcaatgggt ggacagatgc taactttgga
     4381 gaaaagctag taattcaaac aaaaatccct tatactcaag ataccaaacc tttgaaggga
     4441 gcgtagataa tggaaaaatt cacacataaa aaaatggatc caaatgaaat tccgattatt
     4501 tttgtccgtg actgcaaggg aaatgttcaa ggtaaagtct ctattaatga gtggaacgag
     4561 cgtcgcagac ctgctaccct caatgaactg gaaatcaaat tgtatcgtca atctcttgtt
     4621 tattacgcag atcaagagta cgagaaagcc accgatttat tgaaatttct aattgctcga
     4681 acagagtata ctcgctttga atatattgaa cgtttagcaa acatctatca tattatgaat
     4741 gaacctgtca aagaatatca gttattggac accgtcttgt cagtagcaga actgattgcc
     4801 cttcctgctg gattagaaaa gaaactagta cgccgccttt tacgagtaaa gcaacaacta
     4861 tccgatcaag aaaaataact tgcgtttttt taggaaagtg ctatgattat tttgttgaat
     4921 aaatgggatg tagccaaact ggtaaggcac ttgactctga atcaagcaat tgtaggttcg
     4981 aaccctgcca tcccaatttg atgtgcttgc tgaaaaaatg aaccccctgt aaaagaacaa
     5041 tctttttgca gggggattat tgtattattt ttactacttg tatttagttt acataattaa
     5101 attatgaata ataaaatcgg gcgtattctt aatacaaaaa ctgatttacc caataattgc
     5161 taatgctttc tccggaactt tttctctagg aacttcctca tacgtttcta tgtgtgctcc
     5221 tttattgcta attttcaaat aatgattttc ttttaacaca gaaagaccat taaattcaac
     5281 cgttcgttct ttcccattgg catcagcagc tttctgcaca taccttgctg taccatattc
     5341 atttacttcc tctggttttt gtgtctttac atagacctct cctttttcaa ctaatggatt
     5401 tagctgatca agtataccag ggatttctcc ataacttcct tcagtataat atttcagtcc
     5461 aaatagcaaa ataccactaa tcgccgccag tccaatcaaa tatttaatca ctttcatctt
     5521 tctacctcct tgttatatat tcagtatatg ggtcagttaa agaaattcca tccgtcccaa
     5581 gttggagatt tttctcctac tttagaagcg agaatcgagt gtttttttag taaaaatgat
     5641 cgttatttga tattattgac gtgtggataa atcagttttt ctcgttttgt ccatgtaaaa
     5701 aatcatgttg atagcaaagg atgtgttcaa aatgaatcaa gaagaattat ttcaaaaagt
     5761 caaggaaatg attaagaacg gcaatttcga tggcgcaaaa cgatttatcg aagaacataa
     5821 agaacaatta ggaccttata aagagaaagc ccaaaatctt ttaaaagatg taaatatcga
     5881 cagtgtcaaa aacaaattta aaaatctatt caaataagta aaactttcac ttttgtaaaa
     5941 tcaaaggagg acaatgctgc tgcatcgtcc tcctttggtt cttttctgaa tacttcatac
     6001 taaaataaac gtgtcggatc gtaatgataa gtcacattgc cgttcagtga ggcttttccc
     6061 accacatatt tacgattctc caacttcagc cacgcttctc gaaaagccat taattcttct
     6121 ctttttacat caatcttttc gatttttcca tcgatcaaat cttgaataag ttgttcatat
     6181 ggattcattt ttttcctcca tctgctgtca atcaataagt tgtaaaaata ggttcatatg
     6241 cttttttggt atctagatct tctctgactt tgactgtcgt ataaataatt ttttctactg
     6301 ggatactata ataacttcct tcaccattat tgaatcggtg aacgtctttc tttgctaaaa
     6361 taccatttat tttattcgtc agtacacgtt gttcgacact gttacttaca acatagtaaa
     6421 tcacccgaat attattgatc aaatgcaaat cgatttctaa cactacatga tccatgaaaa
     6481 tcccactcct tctttcactt tgattatagc aagtttctcc tctaatttca aaatcgatac
     6541 agattttacc ggataaatcc acaaaactgc ttgcgccatt tcgcacaaag tgttattttg
     6601 tatcatggac tttatttatc ggaggcaata gtatgatcgc gatcggtcaa tttgtttttt
     6661 atattccttt ttttattatg ataagcattc ttttctatta cataaaatgg acaaaaaaga
     6721 agttttcagt tttactggcc tctttacctg ctgtatattt tacttatcaa attttttctt
     6781 ttaggcattg ggaaacaacg tctgtattaa taacacacat catcgaattg acgctttcag
     6841 taatttttct tattatttgg atctattttt tatataagaa tcagaattga atccctcgca
     6901 tgtttaaaaa gaaaacgatt aaagatgcag caaatttctg ccgatcttta atcgtttttt
     6961 ctattctgtt ataccaaaaa aatgtttgaa tcggtgaagg atcgttcctt gttttaattc
     7021 tataaattct tgtgcgatcg ggtacttttc ttccaaattt tctttgttct tttcgatcag
     7081 gcttttcgct tcttcatatt ttttatctgc acatagtgct tttacttcct gtaatacttt
     7141 tcctgcttcc atttgcctca ccctcttgcc attttattgc tttaagtttt atttaagtta
     7201 tacgcattat tctagtttca tcccaaataa ccttttttca tttttactcc tcgaactaat
     7261 cagttttcta aaggctgatt ggttcgtctt ttttattttt cctccatttc attctgctct
     7321 tctgttaatt tatctaatgc tttgattgat gctgcggctc ttgcataatc atagctgtat
     7381 aattccataa atttatcagg cagaacaaac cacgctggat gataaccgtt agctgtgaca
     7441 gggaatcctt tatcttgttg gttatctcca tcccatctca gagcaacacc tttttttcct
     7501 ttccacttta ctaaagcgat cgagtatccc ttctttgttt gtgtgccgtc ttcaataatt
     7561 gctaaaattt ctattttttc ttttggcgca cggacttctt gaggacgaac cattttctat
     7621 tcctccctta tctcattact tcacgaccaa cacactgcaa ggggcatgtg atacgacata
     7681 agaagcggtc gatccaacta atgcttgttg tatagcacct tttcctgtcg ctcccataac
     7741 gatcaaatca atattttctt gtccagggat gacattggca atcaaatttc ttggatctcc
     7801 agtttcaact attgcgtgga tctcagcaat gccgtactct ttggcatcat tgattttttt
     7861 cagcatggct acttctgttc tttgtttttc atctgcatag atttttgaaa aggcataggc
     7921 actatgggtc agctcaactt tgttgatgat tgacacgata aataagtggg cttcattgtc
     7981 ctttgctaag tcaagggctt cagcgaacgc tttgatcgat tgtcttgatc cgtcaactgc
     8041 taccatgatg ttctggtatc ttttactcat tggaaccgcc tcctttttct tttattgtaa
     8101 catctcaagc aaaaatacaa aaaatatacg caatatgtaa ataaaatgat gaacaaaagc
     8161 aatttctttc aagttattta tacatttctt ttctcatcag aacacctgtt ctaatcccat
     8221 tatttctgca ttatgtgaaa ttcctcatca tttttcacat cgagcgaaca tcattctgtt
     8281 acaaaaaacg tggatttgtc ataaattgtc atgcttcttt tacctatgaa atattttcac
     8341 gtgttaaagt attcctcgtt gaacacaaca aataaaactt tttaacgaat aaaggagatt
     8401 tttcatgaca tcacttaaaa ctttactttt tggaacaact ttggctgccg gcgctgcatt
     8461 cttcatggga acgactgctc atgcggacga agcttatacc gttcaatcag gtgatactct
     8521 atcaacgatt tctcaaaaat acgttggtga taactccttg atcaatgcca ttgcagaatc
     8581 aaattc
//
LOCUS       DAXLPQ010000081         8329 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.083, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000081 DAXLPQ010000000
VERSION     DAXLPQ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.083"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..2196
                     /locus_tag="ACF3UO_002510"
     CDS             <1..2196
                     /locus_tag="ACF3UO_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFD3658454.1"
                     /translation="VANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPG
                     GFDGVYTPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRK
                     MQQWLNVNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTY
                     PVSEGNSGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIAD
                     VVVIKGLLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDER
                     NKYLTTEELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTT
                     VIYFAVDLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFA
                     FVSDMSTGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSND
                     TNNDNYIAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPV
                     TEHDRKIYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVS
                     DFAGWLGDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAK
                     RNSDSTALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVG
                     IISFFIDKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            2276..2671
                     /locus_tag="ACF3UO_002511"
     CDS             2276..2671
                     /locus_tag="ACF3UO_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658455.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            2996..3613
                     /locus_tag="ACF3UO_002512"
     CDS             2996..3613
                     /locus_tag="ACF3UO_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658456.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            3654..3953
                     /locus_tag="ACF3UO_002513"
     CDS             3654..3953
                     /locus_tag="ACF3UO_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFD3658457.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            3987..4154
                     /locus_tag="ACF3UO_002514"
     CDS             3987..4154
                     /locus_tag="ACF3UO_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3658458.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(4199..4804)
                     /locus_tag="ACF3UO_002515"
     CDS             complement(4199..4804)
                     /locus_tag="ACF3UO_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658459.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            4929..7916
                     /locus_tag="ACF3UO_002516"
     CDS             4929..7916
                     /locus_tag="ACF3UO_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFD3658460.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            8065..8274
                     /locus_tag="ACF3UO_002517"
                     /pseudo
     CDS             8065..8274
                     /locus_tag="ACF3UO_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT         2827 a         1284 c         1570 g         2648 t
ORIGIN      
        1 gtagctaatt ttggacctac cactgaaaaa atgtacgata atcaggttac tcctaaatgg
       61 ggcaaaaatc tacctaaaaa tattgtattt cttattcaag gtgccttttg gtgtaagggg
      121 attaatccag gtggcttcga tggggtatat actccatatt tagatactgc tgtaaaagag
      181 ttgcagactg atgcagggtt taatggaagc gctgtaactg gagttttgga tgcgaaatgg
      241 gccaaagcgt tatttgatat gagtgctttt gttcttgttc ccggcggaga tagtaaaatt
      301 agaaaaatgc agcaatggtt aaatgtaaat tatttagaat acacgggaat aatgccttgt
      361 gatggtattt atcaaagaaa ttcaaatcaa gcattaattt ttgcattaca agctgaacta
      421 ggatattctc ccagtgaagc aacagggtct tatggtaatg ggacaactag taaaacttat
      481 cctgtgtctg aaggtaactc gggaaactat gtaagaataa ttcaatatgg attatatgtt
      541 aatggttatt ttgaagacgg tacattcgat ggtattttca ctaaatatat gggtttagaa
      601 gtactggcat tccgaaaatt tatggtattg cctgaatata ctgaaatagc agatgttgtt
      661 gtaataaaag gactattgtc tagcgctgga gatattagaa gatctgcaga tggcgcagat
      721 acttctacgc aattaactag atctcaaatc caaacattgg ttgataatga tataaaaata
      781 gttggtagat atcttactgg tactgttgga attggaaaag atgaacgaaa taagtatcta
      841 actacagagg aattgaataa tattttttct aaaaatttat ctgtgtttcc tatctatcaa
      901 gatggaggtg cagcattagc ttattttact tatgatcgtg gcttatcaga tggtaagaag
      961 gctatagatg cagcaaaaaa tctaaatata ccattaacaa cagttattta ttttgctgtt
     1021 gatctagaca tgttagggga agaaattctt gcatatgctg gagaatattt taagggggta
     1081 tctgctgtaa tgtcatatag cgggtatcaa acgggtgttt acggaacaag aaatgtttgt
     1141 tctcaaataa tcaataacgg gtatgcttcg tttgcatttg tttcagatat gtcgactggt
     1201 tatagtggga atttaggttt tcctatgcct agacaatggt cttttgatca atttgttgaa
     1261 tttaccatag gaagtggcaa cggagctgtt ggtatcgatt taatcgctac atcgggtaga
     1321 gatagcggat ttaatgagtt atcaaatgat actaataatg ataattacat tgccaaatac
     1381 aatcagaagg ttataaatca gatggtacgt gcgtatcaat atctatcaca agctggtctt
     1441 gataatcctt ggaaccctca tttgacattt tatagatatg taaattattc tggtttgtca
     1501 tgggacatca tttcttctcc tgtaacagag catgatagaa aaatttatga tgaatatagg
     1561 aataaattaa ctaatagcga gggcctgtat aattatttta tagatcctaa tactggttca
     1621 ataataggtt tgcctcactt aattgtgacg ttacaatcac agatgtttct agccgacaca
     1681 atcaatgata gtgtttctga ctttgcaggt tggttaggag atttaatgac ttgctggggt
     1741 gaagttaaga aattaggaat acaaatggag caaggtgtat ttgcattagt aggtacggct
     1801 gcaggtggaa catttagtct agaagattta taccaagatg ttgacgcggt aaatgtttat
     1861 accttagcaa aaagaaattc tgattcaaca gctttatcgg ctttaaaaac gtactattgt
     1921 gataagggtg ctattgatag atttaatcaa tttgttaaga acagatttgg ttcttcagat
     1981 aaaatcgctt cagtaacaaa tagtttatta gaaaatgacg aaacagttga tatcttaggt
     2041 gtagggataa tttcattttt cattgataaa atagttaata attcacttgg gacagatttt
     2101 acttatcttg attttattgg agatgagggg aaagttgcaa atggattttc tgaaaaaatt
     2161 attcaatttc aagaaaatag aagtaaactt aattaagaat cgtttactat ttaaacagtg
     2221 tccttttcct ttttaaatat atacgataaa ataagtatat gaattgtaaa aggacatgat
     2281 gattatggaa gaaatagaat ggaataatct gactcaaaat aataaaaata attctggatg
     2341 tggaattatc tttatgtttg ttatagtttt gggaatagta gtacttttaa taactgtcaa
     2401 gatagtagat tactttgcga atactcctga agaacaaata cagagaaaac ttcctgagtt
     2461 tgaaagagta ccaccttatg atccaagaga taattcattt caagtaaaaa aattaaaaga
     2521 gtctccaaat gaaatgtggt ttgaagttac agttgaatca agcgacttca aagaaaaaaa
     2581 gaaagaatac aattatattg taaaggcaaa agtatcaaaa agatttattt ttaaccctaa
     2641 attagaaata tatagtgttg taatagaata atagtgttaa aaaaattgta aaagttaaag
     2701 aagtcaaatt ctgatgtgaa aaataaaata taccatggaa gacataaaag aaaaactgga
     2761 taactagttt atttaatggc agaccgttaa ggcctgccat ttttatgtat tttagcggaa
     2821 taaatataat catgcgggag tgtaaactta ctgtttcaaa aagtatactt tttgacatgc
     2881 cttgattttc tttgtttatg tatggcataa taaccacata atacaatttg aaacgtttct
     2941 gatttaatct gattgttttg aaacaatttt agtgaaaaaa gggtagataa aaacgatgag
     3001 aaaatttttt tatatccggg tcagtagtta tgatcaatcg atcgaacgac aactgatttc
     3061 cgcgaaggaa ttaggaatcc ctgaagaata tatatttgta gaaaaagcca gcggcaaaga
     3121 ttttaaacgc cctgaatatc aattaatgaa acggatgttt cgaaaaggag atttactcta
     3181 tctacaatca ttagatagac taggcagaaa taaacaaatg attttagaag aatggcgaga
     3241 attaactaag gaaaagcaga ttgatatttc tgtgttagac atgcctctgt tagatactgc
     3301 tagttacaag caactagatg ggttagagac gcttatctct gacttaattc tgcaattact
     3361 cagctatatg gccgaagacg agcggaaacg aattaatagc cggcaaagag aaggcgtaga
     3421 agctgcgaaa caaaagggtg taaaattcgg cagaaagaaa attgctttac ctcctgaatt
     3481 tcctgcgatc tattctgact ggaaagcagg aaagataact gcagtctatg ctatggatca
     3541 attgggcatg aaacgaaata ccttttatcg acgggtgaaa gaatatgaac ataccttgca
     3601 ccacttttct tgatagatat aacagctatt agacgggaag ggagagtttg aaaatggact
     3661 taacgaatca aagggtcgtt tttactggaa cgctgcagca aatgacacga acccaagcca
     3721 tcggtttggt tcactcttta aacggccatt gtcaatcaag tgttacttca aaaacaaatt
     3781 tcctggtttg tggtcagtat tctaagtcgt tgtttgatga ttctctctat acaaaaaagg
     3841 aacaaaccgc gcgggacttg attgcgttag gtcatgagat taccatttta tcagaagtcg
     3901 aattttatgc gttaattagt caacagttga aagaatggca acggtattta taatcgttag
     3961 taaaatttac aaggaggaaa atttttatga agcgaaaatc ttatgatcgt tggggcattg
     4021 aaataactag ttttaatcga aatattgctt ttcacgtgga gtgtgactgt ggggaattag
     4081 caaaaagtgt ttatcaaaaa aattactttt actgtcctaa atgccatcgc cgatacgggg
     4141 tacatggaac atagaaacga aatagtgcgg tagaaaagcg aatgaatgta gtatatttct
     4201 acaaatcatt cgctttcttt attttataaa tagttggtcg agagatcccg ttttcttttg
     4261 caatctctgc aactggaatg ccttgcttta acatgtccac cacggtttta aaaactaagc
     4321 gtttttgcgg atctgttgag ttaatagaat actcgattgg tcgtccctta tatcggccgg
     4381 ctttttgagc caataatact ccttgccgct gacgttcacg aattttctca cgctcgtttt
     4441 gtgcaatata acttagcagt gataaaaaca tatcgaacat agcggtatcc aggagttcat
     4501 ttccagtatt aaaatctaaa aactgtgcat ctaatatttt taacgctact tttttctgtt
     4561 tcataaaagc aactgtattt tttatatctt cataatctct tcctaaacga tctagtgatg
     4621 taacgatgac gcaatcacct tcacggatat aatttagtaa tttttgaaac tcaggacgct
     4681 cagtatcttt accactggct ttttcttgga ataatttatc aatgttaagt ccttccatca
     4741 ttgccaattg tcgatccaaa ttttgatctt gtgaagatac tcgaatatag ccaatttttc
     4801 ccataaaaaa ctccttttta aaagtgatat aatttacatg taaaatttac ttgtagtttt
     4861 actgctatca tagcattttt aaaaataaat tttatgtaga cttaaaattt acttcatgga
     4921 gggtttaaat ggatgaaatc aaaagtaaca aaaaagcatt tggcatttat ttaggagaac
     4981 ctagtacaga acaattaaac caattttttt atttgcatga aaaagattta gaattgatgg
     5041 agactatacg acgaccagct actagattag gttttgcact acagttagtc tcactacgtt
     5101 ttttaggaac ttttatatta gatcttacca atattcccca aaatgtattg agttatgtag
     5161 caactcaact aaatattgat cctggagaaa ttatctacta tagcaggaga cagaccaggt
     5221 atcagcacac aaaattgata aaatcacatt atggatatca agatttcaac caaccggaaa
     5281 tagaaacata cctagctaac tggcttttaa atagagcgct gtatacaaca gaatcttcag
     5341 atatgttgtt tgatatgctt ctaaaaaaat gtctggatga aaagattgtt ttacctggaa
     5401 ttactacttt ttctcgtttt gttgctagtg caattgaaaa agctgaagag catttatacc
     5461 gacaattgtc tttggttcca actgaagatg agagaaagcg gcttctcaat catttagaat
     5521 taattggaac tccagtttat ggggcaataa tcaaaatgga cattttgaga accccgttag
     5581 ctgacgatag tcataaagaa atagccagag gttttgaccg actaaagcaa tttcaagctt
     5641 tctctactga aaaatggaag atggaatcta ttcctgaagg gaaaataaaa gttcttgcaa
     5701 attatgcatt taaagctaaa gctcaattaa ttcaacgaat gagtgaacag aaaaaactgg
     5761 cgttgttagt ggcatttatt ttcatataca aacgtaaggc tatggatgaa caaattttag
     5821 cactatctaa tttttttgaa actgttttta gacgcgccaa aaataaggaa tctaaagaac
     5881 gtcttcgtac cataaaagat ctagatcgag ccgcatcgac actttcagat attgtagatt
     5941 tagtaatgtc cagtcattct gatactaatg aactatccct tcgcgatcgt atcttagaaa
     6001 aatattctga ggaaaatgtt accgaagctg tatcgcaagt tcggctattg gttaaaaatg
     6061 atcgtgaacc aatagccatt tctgaacttc tgaacactta tcgaaagttc agaaaattta
     6121 ttccggatat tttaactaca ctaacatttg acagcaatga ctacggtaac aactgtaagg
     6181 aactctggac cttcattaat aatagatttc ctaagccgat tacttacaaa atgtttggag
     6241 ctattaaaca tactcttcca aagaaatgga tttattacat tcatgaatac cctgaacaaa
     6301 ctaataaatg tgtattgatt gcagctgtcg aattgttaat tcaatcttta aaacgccatg
     6361 atatttatat tcctcagagt gtcttatata acaatcctat ggattgcttg attgatgaga
     6421 aaacttgggt tcaacaaaaa tacgttttat tagaacaact agatcttcct tcttcagcaa
     6481 atgaaatgtc tttatggtta aagaacgatt tggaactgtc ttataaagaa gcgctaaatc
     6541 gttggcctac ttctaaaatg gccagaatag aaaatgcaga tcgcctggtt gtctctagac
     6601 ttaaaaagac atatgaaaaa aaggaagata agtcttttag acgtcgcatt cagcagttac
     6661 ttcctaaaat tgatttgtca gatttgttat tggaagtaaa ccaacagtta aatcttactc
     6721 aatcatttaa ccacttaagt gacaaggaca ccaaaatgaa agacttggat attagtttat
     6781 tagcagttct tttatcagag tcctgcaata ttggtttttc cccggtttca aaagaaggat
     6841 ttgattcttt aaagtatgat cgtcttgtct atgtcaatca tcattatatt cgagtggata
     6901 cactttcagg agctaatcaa aaaataatac atgcacacag gaaacttgcc acctctaaga
     6961 tatggggtga tgggcatatg gcttcagctg acggtattcg ttatatcaca ccacaacgtt
     7021 ccctatattc tagaagtaat ccaaaatatt ttggccgtgg tcgtgggatc acattctaca
     7081 attttgtctc tgatcaatat atagggttcc acggaatggt cgtttcaggg acactgcgag
     7141 attcgcttta ccttctagaa ggattcctca atcaacccag cgaattaact cctaatcaga
     7201 tcatgactga tacagctggt tatagcgata tgatttttgg tctctttggc ttattagggt
     7261 ttcaatttag tccaagaatt gccaatgata aaggaaccaa actttggcga atcgacgcta
     7321 acgctcacta cggggaactt gatacgttgt ctcaaaattc aattaatatg gaactgattt
     7381 atacccattg ggaggacatt cttagggttg caggttcgtt gaaatctgga aaagtgaatg
     7441 caacagaatt aacgaaatct cttcaacgga atgggcaacc cacgccttta ggaaaagcaa
     7501 taactgagta tggaaaagtt tataagacga aacatcagct tcgttatatt tctgacgaaa
     7561 tatatgcacg gcaaatttta gaacaattga ataaggggga agctcggcat gccttatgcc
     7621 gtaatatttt ttatggacga aaaggaaaac tctaccagac ttattatgat gggatggaag
     7681 agcagctcaa tgcattagga ttagttacta atgccatcat atattggaac tcactgtatt
     7741 tagaaaaagt atttgaacaa atgaaagctg aaggattcga ctgttccgaa gaaatgatac
     7801 gcaggcaatc tccactaatt agtgatcaca tcaattttgt tggtaagtat acgtttagat
     7861 acgaagctga attatccaac ggtaagttac gtccattgaa tgtagaagaa ttctagcaat
     7921 gttcgggttt tgcatgctac cgcactattt cgtatgactg ttccagcgaa tcacttcgaa
     7981 tagaaaaaga gaaaaacacg agaacagcgt taaatcaacg tttcttgtgt ttttactttt
     8041 gtgctaccgc actatttcgt ttctatgttc catgtacccc tttatcaaga agcgcaaaca
     8101 cgccaaattg ccgattggtt gatcggcatg aacgcaagcc ctttatatac cttgaattta
     8161 caacaaaaag gcgtacaagg tacattttca ttaggacgtg tacaaacacc gactttatat
     8221 ctcatttatc aacgccagga agcaatagaa aactttaaaa aagaaccttt tttcctgaat
     8281 aattcatagt tttactaata gtctttccta acattgattt aatagtctt
//
LOCUS       DAXLPQ010000082         8293 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.084, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000082 DAXLPQ010000000
VERSION     DAXLPQ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.084"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            674..1900
                     /locus_tag="ACF3UO_002518"
     CDS             674..1900
                     /locus_tag="ACF3UO_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3658461.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
     gene            complement(2058..2675)
                     /locus_tag="ACF3UO_002519"
     CDS             complement(2058..2675)
                     /locus_tag="ACF3UO_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658462.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            complement(3358..4353)
                     /locus_tag="ACF3UO_002520"
     CDS             complement(3358..4353)
                     /locus_tag="ACF3UO_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3658463.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(4448..5320)
                     /locus_tag="ACF3UO_002521"
     CDS             complement(4448..5320)
                     /locus_tag="ACF3UO_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3658464.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(5333..6760)
                     /locus_tag="ACF3UO_002522"
     CDS             complement(5333..6760)
                     /locus_tag="ACF3UO_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFD3658465.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEVKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(6814..8088)
                     /locus_tag="ACF3UO_002523"
     CDS             complement(6814..8088)
                     /locus_tag="ACF3UO_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3658466.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         2747 a         1524 c         1185 g         2837 t
ORIGIN      
        1 attttaaatt tttacatacc tgtttatgaa aaactaaata atctgtcaaa aaaatatgat
       61 tgttcatttc taaatatgtt ttccaatttt aaaatctttt ttagcatttt tgtttccttt
      121 tcatatggtt tttcgttgtt aatagtgact aggatgatat tcctattttg accattgaca
      181 attaaatata atttttgaat aacgttccct gctattcgag ctaagaattc aagtacgcca
      241 tgacctattt agcgataact acttagagat ttctttttgt tttgggaaga caaaatgcca
      301 tgacaatagc agtagataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga
      361 aattcctatg tgcttaccca agtcaattca aaaattttag ttcatttata aggggatgat
      421 tttattaaat caatagtcta tctaaacaaa aaacaaacct gtgagttttt aggaattgat
      481 aacaatactt tagataaatg gattcgtata tataattttc ccgtaataaa aatagacggt
      541 ataattcgct ttgatgtaga agatatcaaa ggctttatgg atacgttcaa aaagatttga
      601 attttacttt tgactgcata tactaaaagt agcgaaatat actgccttac ttttttatta
      661 aggagtgagg aagttgccta cgaagctttc aaatggaaaa tataaaacta atttgagata
      721 tccaaaaaaa tttaaagaaa ttacaggtat cagttcagaa aaattccaaa aaacatttcc
      781 aactaggcaa ttggctatta aagccgaaaa tgaaatgaaa aagaaaatcg caaaagtctt
      841 aagagaggag aatgcaaatt cattagagct caaaggtcaa ataaaattca aggagtttta
      901 taaatctaaa tggcttccta gatatgagtt agggcaaact actagatccc ataaagctcc
      961 aagcgatata accatcatta atacaaagaa tttatttcga ttgcatattc tgcctatatt
     1021 tggtgagtat gccatgagct atcttaatgc aaataccgaa ataatatcag atgaactcac
     1081 aaaaaagtcg aaggaatatg caaacataaa aatcattaaa tgctatgttc gttccatgtt
     1141 tgatattgca gaggttctaa attatattga atttaatcgt acaacaaaaa taattcaaag
     1201 tattactgca cctaagaaag ttgctctgga agaaaaaaga atacgagaag gaaaacaagc
     1261 tttatcttcg aaagaactca ctgattggtt agacgctgta agagatgatt tcaatgatca
     1321 attactttcc tttcacgatt acactctttt tatgcttact ttatatcttg gggatagaaa
     1381 gagtgagacc tatgctttgc aatggaaata cattgatttt gaaaaccaaa cagtccgtct
     1441 taaatatgcc ttggataaac acacaaaaaa gaaatttaca aaaggtcgaa aagatactat
     1501 tatccaagtt ccggaaattg taatgacact attgcaagaa tggaaatcag tgcaagctga
     1561 acaactattg aagttgaaaa ttaaacagac acctgaccaa tatcttttta gttactccaa
     1621 accttctggt gaagtaaatt gtccagtcca tactgattac ttaaattatc gaattaattc
     1681 tataaaaaaa agacatcccc atttggttca tttaactcct cataaacttc gacatactta
     1741 cgcaacttta gctagacaag gtggggctga tatgaatcaa atttctaacg ctttgacaca
     1801 ttcaggtatt tcaactacaa aaatttatgt gaatacacct gatttagttg ataaagctgt
     1861 gttcgaagcg tttcagcgag gattacaaaa atctaattaa tgtgttctag aatgtgttct
     1921 aaatataaaa aaaagacact ttccaaataa ttggaaagcg tcttgaacgt tgatatataa
     1981 aggatattaa cgttttgaga attgagatgc tttacgagct ttcttaagac ctggtttctt
     2041 gcaaaattat attagcctca actgaaagat ttattttttt gctccctaac ttcattagta
     2101 ataccatgtt tcattcgata tcttctaaac gttctacgat taatccctgt tagctcttca
     2161 acttctttat ctgtagatcc agtcaaaaac aaattaaatg ctaattgaag tcgcggatca
     2221 ttctcacgat attttagcgt acctcccttg tatttccctt ttgctttagc gagtgcaatt
     2281 ccttgttgtt gcgtttcgcg aatataccga cgttcttctt cggcctggta cttgtatagt
     2341 tcgataatta agttattaag taatcgacgt aaattatcat cagtgatacc tgttaacgct
     2401 ggcaaattca aaacttccag tgtagctttc ttcagctgaa ttaaattcat cgtttctgtt
     2461 agctctttat tatttcgtcc aagtcgtttt aattctgtca caacgacaat atcaccttca
     2521 cgtatgaatt tcatcatttc ttgaaatcct tctcgattgg tatctttccc acttgcttta
     2581 tcactaaaaa ttttatcaca ctctgataat aattctaatt gtcggtctaa attttgatct
     2641 aagctgctta ctcgagcata cccaattttc gccataataa aactccttta aaattctgaa
     2701 atccggatca tttttaaatt ctgttgccca actctgttgt catttttcta gataaatggc
     2761 ataaattttc agcgctaagt gacaaaagca actaattttt catgatagat ttttaaatat
     2821 ctcaatctat ctccaaaatt agttgctttt gtagctatag ttgactatga atatgacaaa
     2881 taattagaaa aaactgtgcc aattaaatat aaaaatgaca ctcatttaca ttcaatagaa
     2941 caccaagagc ccaacagggt atactctggt gtccttttaa aaaagtaact ttctgaccta
     3001 attaattgag ctactaaaaa agctatgaaa tgaggaataa aaaagggatc aaaaactttt
     3061 aagtttctga cccttttgag ttctaattat ttcttccaga acgaagaatg ttatctgctt
     3121 tatctgcaat tgattctgtt agaaggactg aaaaatttat gccagccctt ttgcctagct
     3181 tatccgccca ttgaggaatt gttaaggttt ttctgacaag ttctatgtct ttcaaatatt
     3241 tggcaacatc tacacagatt aaaagcatga ttttgtatca tagtctatta taagagattt
     3301 aacaattttt tatatcacga attaataatg aaattatcat tgatagtctt tataaattta
     3361 attgttcttt ttctttactg atgtcttccc catccataat gtgacaggta aaatatattc
     3421 cttttttgtt tcttctttat ttattcgttt catcaaaata gcaacagctg tgtctgctat
     3481 atcattaatt ggttgtatta ctgttgtcag atctggtaat atactccgag tcattaaagt
     3541 accatcatat ccgactacta ataaatcagc tggtacattt aacccctttt cttttgctac
     3601 ttgtaatatt agggccgcat cgatgtcatt tgaagcaaaa ataccatcta ttttaggata
     3661 atcctcaaac atttggaaaa aaatctgttt tttctttaca taagaaatat tgaaatctaa
     3721 tgtcacagtt cgtggaatta actgatatgc tttcatagta tcttcatagg ctagtctccg
     3781 acgattagcc ggagtctgta agtcaattgg accgtttgta tgaataatat tttttgcacc
     3841 ttgtgcaatt aataacttgg ttgcaagttt tccaccattg tagttatcgg attcaacaac
     3901 tggaatatct tcattcatca ctcgatcaat tgcaacaatc ggtaaattct gatatttata
     3961 ttcctgaatt ccttggttat gtgtaccaac aattaaacca tctacttgat cagacaataa
     4021 ctgatttaaa taatttgttt ccttttcttt attattcatc gaattgccta ttaatacctt
     4081 ataaccaatt tcatataact ttttttccaa tgcctcaacg agttcactaa aaaaaggatt
     4141 ggctactgta ggaaatagta acccgacaat gttagttttc ttttgaaata attgacgcgc
     4201 tacaacgttc ggttgataat tgagttcttc tatagcctta taaacattat caatcgtttt
     4261 ttgacttaaa tagccacgat tgtttaatac acgtgaaaca gttgtttttg atacatttgc
     4321 tcttttggca acatcttcta attttgggcg cattctcttg tctctcctaa ataatgcaat
     4381 aattaactat cgaaaaaaag aactctatag aactactata cctgataatc gatatttttt
     4441 ctatgtttta ttcttgtaat tgattcaagc ccaaagcaaa gtttcctagt gttgccgatc
     4501 cattattttt aattaaagga cgcgtaatat atttacttaa cggtggtatt tccacgtaat
     4561 catccaataa tttattaaca ttaacacgaa ttttttctaa caatttttca tttactacgc
     4621 ttccaccaaa tactatttta tccggtcgta taatcaatgt tgtttgaatc acagcttgtg
     4681 ctagataata ggccattaca tcccaaatag gatccgttaa agaaacgtct tcaccctttt
     4741 ttccaaaacg tgcttcaaac gttggtcccg caactaagcc ttctaaacaa tcaccatgat
     4801 aaggacaaat tcctttaaaa tcaatatcat caggatggcg ttttacaaac gtatggccca
     4861 tttctgaatg accaaacgat cctaatagtt ttccgtcaac aacagctcca ccaccaacgc
     4921 cagtaccaac ggtgtaataa actaatgaat ttattttttc attcgataaa gtggacatga
     4981 tgtactctcc ataagctgat ccgttcacat ccgttgtcca agacattgga acattcagct
     5041 catcttgtaa ataacctaac acattaacat ttcgccatcc cacctttggt gtagacgtaa
     5101 tatatcctga ttttggtgaa ttttttcgaa tttctattgg accaaatgat gcaataccta
     5161 atgcatttat atcaaactgt ttaaaatagt caacagtttt tttcaatgtt tccctggggg
     5221 tggtcgttgg acaaattatt tggtcttgta ctcggtaatc ctcgtctccc acggcacata
     5281 caaatttagt cccacctgct tctatgctac caattaacat cataaaacct ccttactcgt
     5341 aagaaattgc atcttttttt agatgataaa ttgtactcga gacaaaagct tcttcactaa
     5401 cactcaaatg catacttggt tgattttctg tataataacg ctctgtaaaa acaagctcgc
     5461 catcattaat aaaaatctct gccgaacttt tatcgataaa cactcgaagt gataatctat
     5521 cacacatctg aatggttcca taccttggat catttttgcc gttacgagtt aaggtacatt
     5581 catttttatc cttagaataa aaaatattga ttaactcttc atcttttgtt tttaatgaaa
     5641 atttgacttc ttgatttttt gatttagtca atagtacatc aattagagct tctttgaatg
     5701 aagcatcttg agcgattatt atttctcctg ccaaattaac tgtcgtttca acgccgctgc
     5761 caactcgaag ttgttctaat tctctcacag gtttcatata caaacgatct ccaattaact
     5821 ctaattctcg aggaagcgtt aatgctcctg cccatccgtc tactttttca ggcatagggc
     5881 tttcccacat atccatccag gccataacaa tacgtctacc atctggagat aaagttgttt
     5941 gtgttgcata gaaatcgtgt cccttatcta attcataaaa atttcctcta atgaattttg
     6001 ctgtctcata atcataatca ccgataaagt agcctgtttc atatagattt aaataatctt
     6061 ttccatttgc ttcaattccc tgaggggata ataaaagaat agattttcca tttaattcaa
     6121 aaaagtctgg gcattcccac ataaatcctt ctgtaagtac ttccttcgct ttagaaattg
     6181 gtccaatgta atcccaattt aataaatcta acgactgata aacaatagca cgacctaatc
     6241 catctttttc ttgactaccc aaaaccatgt aatatttttc atcgtgtttc catacttttg
     6301 gatctctgaa atgatgtgtg ttatcttctg gtgcttttgc tattacagga tttttttcat
     6361 atttagtaaa gtgaatgcca tccgtactat acgccatgtt ttgattttgc caaaaatgat
     6421 ctggatcatt gtctccataa tagtgatgtc ctgtatagaa cagatacaac acaccatttt
     6481 tttcaatagc gcttcctgaa aaacaaccac cttcatcttc ttgatctcca ggagtcaaag
     6541 caagtggtaa agattcccaa tgaactaaat ccttacttct agcatgtgcc cagtgcattg
     6601 gtccccattc agcactatat ggatgatgtt gataaaacac atgataatac ccatcaaaat
     6661 agcaaaatcc atttggatca ttaatccatc ctgatggtgc agacacatga tatcccaaac
     6721 gataacgtgt atttgttaat tctatagctc tttttgtcat aatatattcg ctcactttct
     6781 agataaaatt gttttttatt ctgttggttt ccattatcct cgaataaatg gatccccttg
     6841 aacatctcta tcatcttgtt taagaataaa gaatgcatat atgcctgcta gtaatacaat
     6901 aagagaaata attttaaatg ttggttgata gccaacgttg tctcttaata ttcccaatgg
     6961 tgttgataaa atcacttgcc caatttgagc agctatctga aatcctatca tatagagggt
     7021 tgctgatagc tttgtatcaa aatgaagtgt aaaatagcga aacattggta atgtaaataa
     7081 tggtacttct aaagcatgca acatttttat gcatgaaaca gataatggtg tcgaggcaaa
     7141 cccgcacaat ccaattcgta cacacataat ggttacacct aataacaaag tatttcgaac
     7201 ccctaatttt ctcataatga ttggaacaat tcccatcatt aacgcttcac aaaatacttg
     7261 aatagcattc aatgtcccat atattttttc accattagct gatgttgaaa acaaaccagt
     7321 ataaaatccc ggaaacattt gttgatcgaa taccgtataa aatgtccatg taaaaacaat
     7381 aaagatgatt atcgtccata attgaggcag tttcattaga tcaaacattt cttttaaaga
     7441 aggaatacta tttgattcag cttgttcttg attaaaattt tgatttgctt cccgttcaac
     7501 tttagggttc caaaataata aatttaacaa tagtaaagaa ccaaagaaag atcccgccca
     7561 aaagtttaaa tgaggatttt ttacaaataa aaatcctgcc aaaagcgcta ccaaggcata
     7621 accaaatgat ccccacgccc ttgcttgtcc atattcaaag ccaaataaac gactaaacct
     7681 ttctgacaca gcttcaaaaa ctcctacaga agctaaatat ccagctgaca aaaatagcgc
     7741 tcccataata atgcctaaat taaaattgtt atctagcaat ggcccatata tccatataaa
     7801 aaatggtcca acaagtgtcg ctaatacaga agcaaaaatt aataaatttc gtttaatata
     7861 caatttatct tgtaatgttc cataaataaa catcaaaatt aaggtaacta acgaatttgc
     7921 cgagaatact gttcctacag cactgccaga taaccctaaa ccatttgatt cagatgttag
     7981 ccaaagttga aaaaatgacc accaaacacc ccaagaagca aaaaatagta ataatgtagc
     8041 tgaactttgt aaataagatt gatttttaaa tacgttaact tttgacatat ttttatcctc
     8101 caacgatata tttgtatccc ctttcatgat aaccggttaa catttttaga aaaggacttg
     8161 tactcctaaa attataaaag aaatccgctt acatgtcaac cggttattct atttggataa
     8221 tgccatataa tgtcacagga tatgactttt attggtgtgt cgcttttctt ttttaatggc
     8281 actatttttt ata
//
LOCUS       DAXLPQ010000083         7628 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.085, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000083 DAXLPQ010000000
VERSION     DAXLPQ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.085"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(17..715)
                     /locus_tag="ACF3UO_002524"
                     /pseudo
     CDS             complement(17..715)
                     /locus_tag="ACF3UO_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            794..970
                     /locus_tag="ACF3UO_002525"
                     /pseudo
     CDS             794..970
                     /locus_tag="ACF3UO_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1146..1715)
                     /locus_tag="ACF3UO_002526"
     CDS             complement(1146..1715)
                     /locus_tag="ACF3UO_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3658467.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1789..2112)
                     /locus_tag="ACF3UO_002527"
     CDS             complement(1789..2112)
                     /locus_tag="ACF3UO_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658468.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2266..3078)
                     /locus_tag="ACF3UO_002528"
     CDS             complement(2266..3078)
                     /locus_tag="ACF3UO_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658469.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3405..4280
                     /locus_tag="ACF3UO_002529"
     CDS             3405..4280
                     /locus_tag="ACF3UO_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3658470.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4294..4617
                     /locus_tag="ACF3UO_002530"
     CDS             4294..4617
                     /locus_tag="ACF3UO_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658471.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4614..5366
                     /locus_tag="ACF3UO_002531"
     CDS             4614..5366
                     /locus_tag="ACF3UO_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFD3658472.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5356..7527
                     /locus_tag="ACF3UO_002532"
                     /pseudo
     CDS             5356..7527
                     /locus_tag="ACF3UO_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1373 g         2470 t
ORIGIN      
        1 agaggggggg gattttttat cgttgtggaa tatttaaata ccaacgcttg tcatgaaaat
       61 cttgtgctcc acccttagta tttccttctg gatcgtttgt cgcacgcatc atgacgtata
      121 ctttcttatt agggaaatca cgcatattga aagatacatg atagccaaca tttcctaaag
      181 tattataagc ttgatttacg tctggtctat aaatcccatc agctcttact ctagctagtt
      241 cttttccagt attgtagtcc ataatgaaaa tatactcgta tttataatta gcaatgtgcc
      301 atccagctac atgcaagttt gcgttttcga tttctccgaa ctgatcaatg tgggcgtaat
      361 ttgttccatc tgtcagcgta gaatttgcag cacctgctcg agttggatca attactggtt
      421 tatcctccga agtagttgga ttatcatccg taaaaccatg agccaaatca taggctagtt
      481 tttctttact tacacctatt tcagaaagat aaccgtaagg atctgtatga tcgccccaaa
      541 tattttgtgt tacccataaa tgcgatttga ttcctggttg gttataagga gtgtctaatg
      601 ttaatggaat accatatttc attgctgaat ctcttgccaa ttcaacgtat actttatagt
      661 tcttttcaaa agtttcttta tcatgtgtgt gttgtaactc gatttgcaca ggacttttgg
      721 ctcacgaggt tgtcctactc tacatcttgc tgatagatat gctgaaagga aaacaccaac
      781 attatgtttt gctttttcag ctagaacgag acaagcagga atacctttag aagatatcaa
      841 aggtttttta ggtcataaag atgtttccac tacacaagtc tatgcccata tttctcccga
      901 agtgaaaaaa agatcaatga atcaactaga aaactatata gaagagcaaa taaaaaagca
      961 ctcaaattga gtgctttttt aagctcacta tcactaaaac tatcactaat tttatttata
     1021 agcgaacatg tttctatcac tgatttttta aatctagcga aaaaccctta tcttaaaggc
     1081 gttcgttcaa ttctttggca aggtcttcaa agcctggctt gcctagaagt gcgaacatgg
     1141 ttttcttata gctcatgtag aaaaattttc ttgatgatga ttttatccat caattgagat
     1201 tgactgtttt gctctcctat gatttcagct atgattgtcc gattttgcgg ttttcttctt
     1261 aactggtagt tgattttccc agtttccatc aactcgctaa gcatatccac gactccgcca
     1321 aatccggtct ttttcgtaat aaaacctagt gctaccattc gttcatctag attttttgct
     1381 gtaatcgtca caccagtaat gagcgagtgc tgtaatgttt gggccagctc ttccatccct
     1441 tcagcattgg atacgacgga agctgttttg ttaataggtt cttcgtttat ttcttttggt
     1501 tctttcctct ccactttcac tgtttgacga aggacatcta gttcttgcaa gagcgtttcg
     1561 tattgttctt gggtcagcat cacgccagct actttttcac gattaaatat atatacgcca
     1621 gttcccgcgt ctcgcgcttg agcaaataca tccatcggcg atcgtttcac ttctgtgatc
     1681 gaagatgtgg gaacttctaa tttctttaat tccaatggat ttcctccttt actaatcgct
     1741 ttttattata gcacagactg acttgttttg atcttttttc caaaggtttt atcggttttt
     1801 gcctaaccag taattgatat cggtaagaag tctttcgata ccaaatgaag gatggtacag
     1861 atacgttttt tgatcttcgt tatggtctag tggaaaaaaa tgatcgatga tcactagatc
     1921 tgcataccga ggcggcttat ttcgagtaca tacatgtata gagatccgtt ttcgatgtct
     1981 tagcgttttg ttcagtaccc cagcaagtct tcttgcttct tggtgttcat agcgaaaaaa
     2041 aaagacgatt ttcacttcag gagggtggac atctaaatac cctcgttcct ggagtgtttt
     2101 cagtaaaagc atcccccact ctactgcggg gtgtgcaagt gcttgttgga tcgctagccg
     2161 aaattgatat agtttatctt tggaattggg aaatttttct aatgtttcct gataataacg
     2221 aacttcttct atcagccggt catggatacc aattacgtaa cgaagtcatt cttggtaaag
     2281 tacttttgtc agctttgatt tgctttcgct ctcaaattcg ctattcagcc aaaacagcga
     2341 atcaagcttt tcagtcacaa tcgtcaattt ccgatagtct tgtgtctctt ctatccgttt
     2401 ccaccgcttt tcagtaatct ggttacagct caagcgcaaa attgctagat aatttttttc
     2461 ttttattggc aaaatctgct cctctctaaa tagcaattca ggaaacaatt caaagaatag
     2521 tgttcgactg tctcctaaaa tctcgatttc tgccggatcc tttctttgct tcaataattg
     2581 gatgaacatc tcagaaaagg actgctctcc atcatctgca aaaaaatgcg gaaaatcttt
     2641 caaaaagcaa aacagcagat atcttacttt tctttctgaa ccaaagatct gtgctttttt
     2701 ataagaaaaa gaaaggtggt actcgccaaa ccactttctc aatcgctctt gcgtagaacg
     2761 atcgtacttc tgctcgtaag gttcattcaa tagcagattt ttcagtaaac aaaacggggg
     2821 tgattggatc agaaaaacaa acaagagata aggttcgcta tatccttgat cataaactaa
     2881 ctgaacggtt ttcttatgaa gaatcagctg aatgggacag tcgctttccg ccaaacgttt
     2941 cagatgccga tccactgttt taacatcgat tttcagttct tcagctaaat cagcttttcg
     3001 ccagatcaaa tctttcatta gattgattag tgaaaataaa ttctgtgcat tttttgataa
     3061 tagtttttgc catctcatcg atcatttctc acctgatttc taaacatatt gtttgatcaa
     3121 aatgggttca ctcctaaaaa gataaaaaac tccctttcta tttatttaaa tacgcaaatc
     3181 ttcctcatta ttttttattt tactcaattt aatcgtattc tcatttcaaa acgaatgtac
     3241 tttaaaaaaa cataataaga tcactttgct tgtaggatgt attcccttcc attacaatga
     3301 aataaatagc gattttatga gaaggtgatg tgaaaatgga agaaaaaata gaagaatcca
     3361 aacaaaaaat cgatcagttg atataagaat tagaaaaagc ggtcatcggc aaacgttcaa
     3421 ctatccaatt gatgatcgtg gccctattag caggtggtca tgtcttattc gaagatattc
     3481 ccggtgtagg taaaacgtta ctggtcaaag cactagcaaa agctgtacag ggaaccttca
     3541 gcagagtcca atgtactcct gatctgctgc ctagtgatat tcttggtttt tccgtataca
     3601 attcacaatc aaaagagttt gaatttcgtc cgggaccgat ctttaccacg atcttgttag
     3661 cagatgagat caatcgtacg actcctcgta ctcagtcagc acttttagaa gcaatggccg
     3721 agaatcatgc aacgatcgac aacaatacat accctctaga caatcatttt tttgtcttag
     3781 ctacgcaaaa tccaatcgag tacgaaggaa catatccttt gccggaagca cagctcgatc
     3841 gttttttatt ccgactacaa atcggttatc cttcttttga tgacgaactt ttgctacttt
     3901 tggataaatt cgaaaaagtg ttggataact taaatgaagt attgaacagt tatgaaatag
     3961 aagaaataaa aacaaatgtg gcgaatgtct ttgtcagtcc cgaagtggca tcttatgcct
     4021 tgcagttagt gtcagcaaca agaagtcatg ctgccatcca gcttggcatc agtccacgag
     4081 gaagcctttc ctttattcag gcagcaaaag cttatgcttt aatccatggg agaaattacg
     4141 tcacgcccaa agatttgcag gatttagttc cttacgtgtt ttcccatcgc ctgatttttt
     4201 acgatcgttc attgaaggaa gacgaaaaga aacaaatcat tcatactctt gttgcacaaa
     4261 ttcctattcc tgtgaggtag attgaggtag acaatggaaa aaatcaaaga ttatttcatt
     4321 aattttgtgt tatttctggt atatttcatc attgtgcttt ttgctcttgt attcaacaat
     4381 tctttaggct ggttcttgtt ggcctttttt actctttatg tatcatggag cttgatttca
     4441 ttaagcagct ttctaaagaa actttcggtt acttgtacat tgcagccact cgtttatcgc
     4501 aaaaaaagta tgcaggttat tttttccata gcaaaaaaga gaactttttc tttacctctc
     4561 cctcgtttac aaatcggctt cccagcaatc tttgcagaaa aaaacaagag attttgattc
     4621 ttacaaataa accgcaagaa gtccaattgc tttggcagcc aaaagaaaga ggatgccatg
     4681 aaacattaac tgtcattttt acagcctatg atagtctagg acttttcaga aaaagtgcaa
     4741 aaagagagat ctcttttcct gtgactgttc tgcctgcttt ttgtaagatt caagcagaaa
     4801 aattacagag agttctggaa aaaaaacagc agctgaacgc gtaccaaaga ggtcttgatt
     4861 ttcgggaaca tcgcgcttat cgtccaggtg attctttcaa ccgaatcgat tggaaattgt
     4921 ctgctcatac tcaagagtgg ttataccgtg aatacgatta tcaagaagaa gaatgttctc
     4981 ctcttttttg cttttggggt tcgcccagtc caaaatttga acctctgcta gacttgtatt
     5041 tttctttatg gcatttgaga aaagaaaagc agccggaact tctgatatta ggcaaccgcg
     5101 cctttcatgg caaagacccc ggtcatacct attttgcttc tttggaagct ggcgatgaga
     5161 aaactttttt cgcacacttg aaaaaatatg caaaaaaaca aatcgtcctc tttgttcctg
     5221 agaattctcc tgaagtctca gaagctattg aaacattgtc aaaagatcga acggtttatc
     5281 ttgtttattt cgtagaaaaa caactcatgg tccaagaaaa agacaagata tgttcattgc
     5341 caggaggtga atggattgac gattaaacgg gaaaaatggc tgcgtggcgt ttactccttt
     5401 gtgatactaa gtgtaggtgc tccgatattt gtagtagcta atcaattgca aaacagctac
     5461 cttcttatcc taactattgg tgtcctatgc cttattgtct gctgtattcc taaaaaatgg
     5521 gtacgtttgc tgctttcttt gccagtaatg ataggttgtt tgtttttata ttttccttcg
     5581 aagacatttt ccatattatg gatcttacag tttttttcgt cagttacaga ggaattcttc
     5641 catctatccc aaggtaaact ttattatttg ccagaaaaga cagctttttt tctcataatg
     5701 ttgctgatct atttatttat tacattgacc gtggattacg actattggta cgcacccttt
     5761 ctttctttga tggcttactt catgatgctt accgtttttc ggaaaaaaga tttactgtac
     5821 gaaatgattg cggtagtaac tgttttgttc gtgtatctgg cagcaaggca atttttctcc
     5881 atccggttgt tgtcgagaaa cactcgattc cagtcattga ctacagttct gcttatttgt
     5941 ttcttaactt ttagcgctat cttgccttta tatcttccga aagtacacca atctctcgag
     6001 gaaacgagtg aaccgatccg agaatatctt aatgatgaag ggctttatga cacactccat
     6061 gagtatcaat taaccggaag tgcaagaaca ggcttcagtg agaatgatga acagcttggt
     6121 ggacctttat atgataatgg cgaagttgtt tttacagcga accaaaaagg aaatggctat
     6181 tggaagatcg aaaataaaaa tcattacacc ggttctggat gaatagaaga tcaggacgca
     6241 cccatccaac caatccaaga attccctgtt gacatcacga gctaccaaac cgttatagaa
     6301 gacaaagaaa acattacatt gaccctaaaa aaacaagctt tcttacctta tccttatgga
     6361 aatactacct tgactgattt ttcattagct agtggacaaa cgctttacta tttgcctgaa
     6421 agccagcgat tcattcctgt cccgaatgaa tcgacacgtt ctgcaacttt acaaacagaa
     6481 aggttagttt ttacgagaga agaattaaaa agcagtcagt taaaagctga tgatttagaa
     6541 aatcagcaga caaatcttca attgccaaaa agtttgccta aacgtattga ggacttggcg
     6601 gtcgaattga ccaaaaatga agcaacttta attcgtaaag tcgaagctgt ctaacagtat
     6661 ttaaaaacaa gcggaaattt ccgctattcc aaaacggata ccgggcatac tccaaaagaa
     6721 cacgattatg tggattattt cctctttgat tcaaaagtcg gctattgtga caacttttca
     6781 acttctatgg tcgtccttct tcgaacactt ggtatcccag ctcgctggac aaaaggtttt
     6841 acaaatgggc tcagaacagg cacagataat caagggaatg aggaatacag cattctcaat
     6901 agtcatgctc attcttggcc agaggtatac tttcctggat ttggctggct tccatttgaa
     6961 ccaacccctt catttgccaa tccaatgggt tcacaaccag ttgctgaaac aaccgaaacc
     7021 gtccagcctg ctatcgaaca accaaatgaa agcgaaaata tggcagaaac tatttccagt
     7081 gagagatctg aggtcattcc atcagaagaa acaacactca caccagctta taaaatcgtc
     7141 ttattcagcc ttggagtgtg tttatccgtc ttgttgttct ttctattgtt attcagaaaa
     7201 tctctgcgct ggacaagtta tcttatctat cttcattttt ttgcttctac taatacgatt
     7261 gcatatcaaa aacttcttaa ccctttggaa acattggtac cgcgcaaacc cgcagaatct
     7321 ttgcaggaat atagcctgcg aatagaacaa gaattcaagc tagatctgcg tttcattcga
     7381 ttaactactc aatatgaagc agaaatatat ggacgacaag cagatccggt aaaattcgat
     7441 aaaaaaacct atttagaaat aacgcatata ataagaaaaa cggtatacaa aaaaattctg
     7501 acaaaaggga gccgcttcaa aaaataagat aaaatttctg gagaatctac ttctcgaatg
     7561 ccgagaacca gctgattgag tatcgattac tcgaaaaaaa ggttgtgaca cgttttttgt
     7621 cacaacct
//
LOCUS       DAXLPQ010000084         7601 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.086, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000084 DAXLPQ010000000
VERSION     DAXLPQ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.086"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(138..428)
                     /locus_tag="ACF3UO_002533"
     CDS             complement(138..428)
                     /locus_tag="ACF3UO_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658473.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="ACF3UO_002534"
     CDS             complement(546..806)
                     /locus_tag="ACF3UO_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658474.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="ACF3UO_002535"
     CDS             complement(943..1356)
                     /locus_tag="ACF3UO_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFD3658475.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="ACF3UO_002536"
     CDS             complement(1812..2297)
                     /locus_tag="ACF3UO_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658476.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="ACF3UO_002537"
     CDS             complement(2436..2651)
                     /locus_tag="ACF3UO_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFD3658477.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="ACF3UO_002538"
     CDS             2875..3675
                     /locus_tag="ACF3UO_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3658478.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="ACF3UO_002539"
     CDS             3694..5562
                     /locus_tag="ACF3UO_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFD3658479.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="ACF3UO_002540"
     CDS             5555..6046
                     /locus_tag="ACF3UO_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFD3658480.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /locus_tag="ACF3UO_002541"
     CDS             6034..6588
                     /locus_tag="ACF3UO_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFD3658481.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..7601
                     /locus_tag="ACF3UO_002542"
     CDS             6606..7601
                     /locus_tag="ACF3UO_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFD3658482.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2708 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg a
//
LOCUS       DAXLPQ010000085         7426 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.087, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000085 DAXLPQ010000000
VERSION     DAXLPQ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.087"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            256..1044
                     /locus_tag="ACF3UO_002543"
     CDS             256..1044
                     /locus_tag="ACF3UO_002543"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658483.1"
                     /translation="MEKINESKVSVCKEKGESYFLETLSLKQQEDKLFSEWEKEECLK
                     GYYGINQDGLADESSYLQSLPKIAFILKEAYGKENFDMRPYYYDGAHAGSKTWRTAPL
                     WIAGISKIYEENKSTIAQIKTEKRNMGWKEFNQEYIRKVAILNLNKQCTTNGKLTDRK
                     YFQSGIDNKKFINKQIEIYNPEIIICGGTFYPFYDRIYDYKNFDTKYESANQNKQYAE
                     GYKDKKGRLIINTFHPGAIKKEEPWYDSIMEIVERFKSEGLFAK"
     gene            complement(1130..1234)
                     /locus_tag="ACF3UO_002544"
                     /pseudo
     CDS             complement(1130..1234)
                     /locus_tag="ACF3UO_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1575..2039)
                     /locus_tag="ACF3UO_002545"
     CDS             complement(1575..2039)
                     /locus_tag="ACF3UO_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658484.1"
                     /translation="MPRINRKKPTGDFESVFDEELEELETPNDTIDSIPETEVTVSNS
                     FPSDKETITENFNEANRFGLSKTSKSTSSELVARTFKYKKETIQRVESLVYKDQRHSK
                     KIPGTKGFISDFMDNAIWQHLLQLGLATEEEVQKHLNSYSKYPLNFDNYEKK"
     gene            complement(2039..3004)
                     /locus_tag="ACF3UO_002546"
     CDS             complement(2039..3004)
                     /locus_tag="ACF3UO_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3658485.1"
                     /translation="MAVVLTVAANKGGVGKTLITINLAGAIRRSFPEAKILVVDTDAQ
                     GNSTKSFRVKVAKDQNTIYDVFMDNATVEETIVQTYDDHIDVLPANSDNNYLEFDKME
                     QFRDTILEWFVSLLKKFKDNLTEIMTVSGLKKKMNNIIDPSANYFNALDGKFDNVSDK
                     YDYIIFDTPPELKQVTSSVLSIADVVIVPYEPDLNGVDGVTHLISRVNTLKEKYNPNL
                     RIGGVLANKVYNTNLHAKMINAMMKYTNRNNYHYFDSELPRSITFADKLVRNGMPITM
                     SSPENKFAQHFYKLIIEMNKLGLLSKNGKELEIPHKLYVESDGEE"
     gene            3391..3717
                     /locus_tag="ACF3UO_002547"
     CDS             3391..3717
                     /locus_tag="ACF3UO_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD3658486.1"
                     /translation="MKKNSKEFRNEYDRFVLKFLIDNYYISRIDLSKAIGLAPSYVRE
                     FYNGSRSFGNEALEKLESTIFNLYKPLLENHSFELNQVQEMIESIDSEEELELFRLKG
                     ANVLDI"
     gene            4102..5595
                     /locus_tag="ACF3UO_002548"
     CDS             4102..5595
                     /locus_tag="ACF3UO_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFD3658487.1"
                     /translation="MTASLDVVYSTILQNGIRKFKYKNSRLKPVSFSEQTGKGAIFAY
                     RSKEHMVEGIGLVITSEEGIIENNNAFSHWTPNVFRYGTYTDEGRMFTKGHSEDNLRQ
                     INTFFVDFDTLDPNFDYGEILLASHELGFMPTMVLRTPHGYQAFYVLDQPAFVTKKSN
                     FKVINVAKMISNNLRKTLAKDFPVDVNANHFGITRMPNEDNTLFFEPQYRYSFADWIN
                     WSMRVDADKAVTYRNVFELPSNQDFRQVDEPWFRLLMRSEKIKGEKGRYGRNNVIFTL
                     SLAYFSSGYEIEECELAMLEFNDRLAYPLTDRELTRIIRSAYSGKYQAAHREKIILLC
                     QEWIDENLSEEQLFNKKKGWWKFKKERKVRKYSHSHEWAQDLLAYLNQQSYTYKPYIV
                     STKKELREELKIPERSLDKVLKQLKNENKIYYRVRSGRNGGITLASVHGLMRSIIRVK
                     KEVQEAYFSAISEVFGLARTFIYSTLEQLIEAPKKAEQMELFEVDTG"
     gene            5753..6037
                     /locus_tag="ACF3UO_002549"
     CDS             5753..6037
                     /locus_tag="ACF3UO_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFD3658488.1"
                     /translation="MGVNTFVYPYPVSVFIIQRLGMTVEEFCELHGYRQSTVATWAYR
                     NRPVKVLPCDFLYCLSLASGLSMDKVYQDLLLLEEKFLQSLDPKKEKKSI"
     gene            6073..6198
                     /locus_tag="ACF3UO_002550"
     CDS             6073..6198
                     /locus_tag="ACF3UO_002550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658489.1"
                     /translation="MFRVEIVEKKTIEKLEKAVNNILISKGDKVQTIEYAAVKKI"
     gene            complement(6425..7105)
                     /locus_tag="ACF3UO_002551"
     CDS             complement(6425..7105)
                     /locus_tag="ACF3UO_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3658490.1"
                     /translation="MNHFKGKQFQKDVIIVAVGYYLRYNLSYRDVQEILYNRGINVSH
                     TTVYRWVQEYGKLLYNIWKRKNKQSIYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPRVLVTDKAPSIASAFKKLQAHGFYQRTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYRSLRTASTTIKGMEAIRGLYKKNRKEGTLFGFSVCTEM
                     KILLGIPA"
     gene            7291..>7426
                     /locus_tag="ACF3UO_002552"
     CDS             7291..>7426
                     /locus_tag="ACF3UO_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HFD3658491.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     F"
BASE COUNT         2468 a         1163 c         1397 g         2398 t
ORIGIN      
        1 ctcctggtat gttttcttct agtctacaca ccttaatttt tctgtctagt taattgtagc
       61 ctatccagag tataatcatt gtaaggtcaa gtatttgact ttttcgatta tgagagcgtt
      121 accttttcta ttactgaagc ctttataaaa tggcgaaata atagaagaaa ctgaaagctc
      181 ttaataaata gacaaactac gttccaatag acgttttaaa aagggtatga aatacagcat
      241 acaaggagtg aaaaaatgga aaaaataaat gaaagtaaag tatcggtctg caaagaaaaa
      301 ggtgagtctt attttttaga aacgttatcg ttaaaacagc aagaagataa gctgttttct
      361 gaatgggaaa aggaagagtg cttgaagggg tattatggga taaatcaaga tggactggca
      421 gatgaaagta gctatttaca atcacttccg aaaattgctt tcatcttaaa ggaagcatac
      481 gggaaagaaa attttgatat gcgcccttat tattacgatg gtgctcatgc tggaagcaaa
      541 acttggcgaa ccgccccttt atggattgct gggatatcta aaatttacga agaaaataaa
      601 agcactatag ctcaaataaa aactgaaaaa agaaatatgg gttggaaaga gttcaatcaa
      661 gaatatatac gaaaggtagc tatcctaaac ctcaacaaac aatgtacgac taatggaaag
      721 ttaacggatc ggaaatattt tcaatccggt atagataata aaaaatttat aaataaacaa
      781 atagagatat acaatccaga aattattatt tgtggaggaa ccttctatcc gttttatgat
      841 cgtatttatg attataaaaa ctttgatacc aaatatgaaa gtgccaacca aaataaacag
      901 tacgcagaag gatataagga taaaaaaggc cgattgatta taaatacttt ccatcctgga
      961 gccataaaaa aagaagagcc atggtatgac tctataatgg aaatagttga aagattcaaa
     1021 agcgaaggct tgtttgctaa gtaagtgagt tccttcttcc aaattacaaa aaataatgga
     1081 taggctacac accttaattt ttctgtctag ttaattgtag cctatccagt cgcgcacgtc
     1141 ctaagcattg cgcagttttg gtaacggatt gattattttt gaaataagac tctatgacta
     1201 ctagttcgtc tgttgtaaga tgggtgtagg tcatttgtac tcactcctta ataattcttt
     1261 ggtcggaact attttgagtg tagcacaaat gatcttttta gttgtctagc ttaattttac
     1321 aatcgacgtt gtaaaaatta tatatgatta tgtaaaaaag aataaaataa ctaaaaaatt
     1381 taactgataa aaaaattgta atgacaaaag aacggatctt ttatagatcc gctctttttg
     1441 atgagatagt aatatttaaa gtaatataaa tagtaatatt atggtaatac acatagtaat
     1501 atatatcgta atattgtggt aatacaaata gtgatataaa aatttcgccc tataaaaaaa
     1561 gaaatagcga taagctactt cttttcataa ttatcgaagt taagtggata cttactatag
     1621 ctgtttagat gtttttgaac ttcttcttca gtggcaagtc ccagctgtaa taaatgttgc
     1681 caaattgcat tgtccataaa atctgaaata aatcccttag tcccaggaat ttttttagaa
     1741 tgtctttggt ctttgtacac taaactttca actcgctgta tagtttcttt tttatattta
     1801 aatgtacgtg caactagttc agaacttgta gatttcgaag ttttgcttaa gccaaatctg
     1861 tttgcttcat taaagttttc ggtaattgtt tctttatctg agggaaaact attgctaaca
     1921 gttacctcag tctcaggtat gctatcgata gtgtcattag gtgtttctag ttcttccagc
     1981 tcctcatcga atacagactc aaaatctcct gttggttttt ttctgtttat tcttggcatt
     2041 attcttcacc gtcactttca acatataact tatgaggaat ttctagttct ttaccatttt
     2101 tagaaagtaa acctaacttg ttcatttcga taatcagctt ataaaaatgc tgagcaaatt
     2161 tgttttcagg tgaactcatt gttatcggca ttccgtttcg aactaattta tcagcaaagg
     2221 taattgatct tgggagttca gaatcaaaat aatgataatt gtttctatta gtatatttca
     2281 tcattgcgtt aatcattttt gcatgtagat ttgtattata gactttgttg gcaagtacgc
     2341 ctccaatgcg taaatttgga ttgtattttt ctttcaatgt gttcacacga gatattaagt
     2401 gtgtaactcc atcaacccca tttaaatcag gttcataagg gacgataact acgtctgcaa
     2461 ttgaaagaac agatgaggta acttgtttta actctggtgg tgtatcgaaa atgatgtaat
     2521 cgtatttatc actcacatta tcaaatttac catcaagagc attaaaatag ttcgcgctgg
     2581 gatcaataat attattcatt tttttcttta atcctgaaac agtcatgatt tcagttaagt
     2641 tatccttaaa ttttttaagt aaagatacaa accattctaa tatggtatca cgaaattgtt
     2701 ccattttatc aaactctaaa tagttgttat cagaattcgc aggaagaacg tctatatgat
     2761 cgtcatatgt ttgaacaata gtttcttcaa ctgttgcatt atccatgaag acatcataaa
     2821 tcgtattttg atccttagct actttcacac gaaaagactt tgtactattt ccttgagcgt
     2881 cagtatcaac gacaagaatt tttgcttcag gaaaactcct acggatagct cctgcgagat
     2941 tgattgtaat aagagtttta ccaacaccac ccttgtttgc tgcaacagtc aaaactactg
     3001 ccatttttca attcctccct aaataatata atagtaatat ttttggtaat agataagtaa
     3061 tatagataat aatatataaa gtaatatttt gttaatcgta acaatacgag aaagtaatat
     3121 actatattac tttctcatat tagcataata cgttgtcgaa atcaacaata aatcaaaaaa
     3181 taaaacagca gattttatat tatgttacta ttgataatag taacataata gtaagataat
     3241 atattatatt actattatgt taccttttaa acactgatag atagggaatt tgaagaatta
     3301 tattaaaaaa aggattgtat ataaattttt ttgatggtaa tattataaac gaggatgttg
     3361 ctataattaa caacgaagag gtaagatttc atgaaaaaaa actctaaaga gtttagaaac
     3421 gaatatgaca gattcgttct taagtttttg attgataatt attatataag ccgaattgat
     3481 ctatctaaag ctattggatt agctcctagt tatgtgcgag aattttataa tggatctcgt
     3541 agctttggaa atgaggcatt agaaaaacta gaatcaacaa tttttaactt atataaacct
     3601 ttgctagaga atcattcatt tgaattaaat caagtacagg aaatgataga atcaattgat
     3661 tctgaagagg aacttgagtt gttcagactt aagggagcta acgtattaga catttagata
     3721 atttctactt gatttggtaa attatattta caactttcaa cagattcggt aagataaaaa
     3781 aaatatataa aaaagagacg gataaacaag tgaattggac ctcactcatt tatctgaatc
     3841 acataaagca actatgtgtt ctcgctcgtc tcaaggaaat tatgtaagtg gtagccaacc
     3901 acttatgtga tttgaataaa tctgttcgga ctaccaatcc gaacctgtag gtttatttta
     3961 ccatttttag acgggcaact caatagataa acgcttattt gtcatgcttt ctttagattg
     4021 ttttgatatt tctagcgatt gagagaacac agatcgaacg attatttgtg ttctcttttt
     4081 gtttagaaag gataagtagg catgacagct tctttagacg tcgtttattc aacgatctta
     4141 caaaatggta tccgtaaatt taaatataaa aatagccgcc ttaaaccggt ctcttttagc
     4201 gaacagacgg ggaaaggggc tatttttgcg taccgttcaa aagagcatat ggttgaggga
     4261 ataggcttag tgatcacgtc tgaagagggc attatcgaga ataacaatgc gtttagtcac
     4321 tggaccccaa acgtcttccg ctatggcacg tatactgatg aaggcagaat gtttacaaaa
     4381 gggcattctg aggacaattt acggcaaatc aacactttct ttgttgattt tgacacctta
     4441 gacccaaatt ttgattatgg agagattttg ttggcaagcc atgagctagg atttatgcca
     4501 acaatggttt tgcggactcc ccatggttac caagcgtttt atgtactgga tcagccagct
     4561 tttgtgacaa agaaatccaa ttttaaagtg atcaatgtgg ccaaaatgat ttctaacaac
     4621 ttgcgaaaga cattagccaa agattttcct gtagacgtca atgccaatca ttttggaatc
     4681 actcgtatgc caaatgaaga caatacctta ttctttgagc cccaatatcg ttatagcttt
     4741 gcggactgga tcaactggtc aatgcgtgtc gatgcggata aagcagtaac ctacagaaac
     4801 gtttttgaat taccgtcaaa tcaggatttt cgccaagtgg acgaaccctg gttccgtcta
     4861 ttgatgcgta gtgaaaagat taagggagag aagggaagat atggtcgaaa taacgtcata
     4921 tttaccctgt ctttagcata cttttcttcc ggatacgaaa tcgaagagtg cgagttggcc
     4981 atgttagagt tcaacgatcg attagcctat cctcttactg atcgggaact gacacgaatt
     5041 atccgatcgg cttattcagg aaagtaccag gcagcgcaca gagaaaaaat tattctatta
     5101 tgccaggaat ggatcgatga aaatttatct gaagaacagc tgtttaataa gaaaaaaggc
     5161 tggtggaaat tcaaaaaaga gcgtaaagtg cgcaagtatt cgcacagcca tgagtgggcg
     5221 caagatctct tagcttattt gaaccaacaa tcatacactt ataaacctta tatcgtttca
     5281 accaagaaag agttaagaga agagcttaaa attcctgaac gctccttgga taaagtattg
     5341 aaacagctga aaaatgaaaa taagatctac tatcgtgttc gttccggtcg caatgggggg
     5401 ataactttgg cgtcagtgca tggcttgatg cgatcgatca ttcgagtgaa gaaggaagtc
     5461 caagaggcgt attttagtgc tatttcagag gtttttggat tggcacgtac atttatctac
     5521 tcaacgctgg aacaactcat agaggcacct aaaaaggctg aacaaatgga attgtttgaa
     5581 gtggataccg gataaaaata aaacccgcaa attgcctttt acattatatc tttgatacgc
     5641 tctccgagtc agaggtttta caggtcttag ggaattccct tgattgcaat gtttggataa
     5701 gtgaggtact attatcgcat atgtgattat atttcttagg gggttaccgt ccatgggagt
     5761 gaatactttt gtttatcctt atcccgtcag tgttttcatt atccagcgtt taggtatgac
     5821 tgtggaggaa ttttgtgagt tacatggtta taggcaaagt accgtagcaa cttgggctta
     5881 tcggaatagg cctgtaaaag tcttaccctg tgattttctg tattgtttga gcttggcttc
     5941 tggtttgtca atggataagg tttatcagga tttattactg ttggaggaga aatttttaca
     6001 aagtttggat cctaaaaagg agaaaaaatc gatttaaagt ttagtaagtt tgaaaggaag
     6061 agggggataa taatgtttcg tgtagaaatt gttgaaaaga aaacgattga aaaattggaa
     6121 aaagcagtga ataatattct tattagtaaa ggggataaag tacagactat agaatatgct
     6181 gcagtaaaaa agatttaaac gtctattatt ctgctatgat tgtatataag gcttgaggat
     6241 gttttgagtt gttaggaatc taagggaagt aaaaatattt ctataggaga acagaaaaga
     6301 tggataatga tcattgtgag aatgtaaaca agttagaaag tgcgggtaaa acttattata
     6361 ttattggtgc ggttctgttg caaagttcca aaatgaacaa tactagtcta acactagcta
     6421 tagtttatgc aggtattcct aataatatct tcatttccgt gcagactgaa aacccgaaga
     6481 gagtgccttc ttttcggttc ttcttatata atcctcgaat ggcttccatg cctttaatcg
     6541 tggttgaggc tgttcgtaag cttcgataaa atttgtttcg tctcttgatg ggacgatgat
     6601 cttgttcaat gaggttattt agatatttca ccgtgcgatg ttctgttcgc tggtaaaacc
     6661 cgtgtgcctg taattttttg aaggcactgg caatagaggg agctttatcg gtcaccagaa
     6721 cccttggttc atcgaactgt ttaactaatc tcttgagaaa ggcgtaagct gcttgtgtat
     6781 ctcgcttttt ccgtaaccat atatccagag tgagaccatc tgcatcaatg gcgcgataaa
     6841 gataatgcca ttttcctttg attttaatat aggtctcgtc cattttccac gaataaatgg
     6901 actgtttgtt tttcctcttc caaatgttgt aaagtagttt cccatattcc tgtacccaac
     6961 gatagacagt ggtgtgagac acgttaatac cacggttgta cagaatttct tggacgtcac
     7021 gataactcag gttgtaccga agatagtagc ctacagcgac aataatcaca tctttctgaa
     7081 attgtttgcc tttaaaatgg ttcatcttcg ttactcctcc tagttcctat taaactcagt
     7141 ttaccctata atggatctga ggggaaactt tgcaacagaa ccagttgaag aacaaactgg
     7201 aatcaatcgc cgaacgttta gaaggtatcg agcaagatat aacgtgacag tagatcaaag
     7261 aaaaaacaat gaaaagaggg atagttaatg atgagtacgg ttattttagc tgaaaaacca
     7321 agccaggcat tagcctacgc aagtgcttta aaacaaagca ccaaaaaaga cggttatttt
     7381 gagatcaaag acccactatt tacagatgaa acgtttatca cctttg
//
LOCUS       DAXLPQ010000086         7244 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.089, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000086 DAXLPQ010000000
VERSION     DAXLPQ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.089"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..105
                     /locus_tag="ACF3UO_002553"
     CDS             <1..105
                     /locus_tag="ACF3UO_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3658492.1"
                     /translation="MEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            418..915
                     /locus_tag="ACF3UO_002554"
     CDS             418..915
                     /locus_tag="ACF3UO_002554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HFD3658493.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            916..1332
                     /locus_tag="ACF3UO_002555"
     CDS             916..1332
                     /locus_tag="ACF3UO_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HFD3658494.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            1352..2896
                     /locus_tag="ACF3UO_002556"
     CDS             1352..2896
                     /locus_tag="ACF3UO_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658495.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            3039..3263
                     /locus_tag="ACF3UO_002557"
     CDS             3039..3263
                     /locus_tag="ACF3UO_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658496.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            3278..4147
                     /locus_tag="ACF3UO_002558"
     CDS             3278..4147
                     /locus_tag="ACF3UO_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFD3658497.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            4128..4862
                     /locus_tag="ACF3UO_002559"
     CDS             4128..4862
                     /locus_tag="ACF3UO_002559"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3658498.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4895..5803
                     /locus_tag="ACF3UO_002560"
     CDS             4895..5803
                     /locus_tag="ACF3UO_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFD3658499.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5800..6342
                     /gene="sat4"
                     /locus_tag="ACF3UO_002561"
     CDS             5800..6342
                     /gene="sat4"
                     /locus_tag="ACF3UO_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFD3658500.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            6435..7229
                     /locus_tag="ACF3UO_002562"
                     /note="aph(3')-IIIa"
     CDS             6435..7229
                     /locus_tag="ACF3UO_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFD3658501.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2519 a         1153 c         1620 g         1952 t
ORIGIN      
        1 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
       61 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag cttaaatcat agataccgta
      121 agggatttta ttctttattt aaaactttgc aacagaaccc tttaaagtat tctgcttcat
      181 cacccattag gtgatgaaaa aagaacccct ttctgattta gcggacaaat actttgacct
      241 aatctcagaa gatataaaag aaaaaataat aaaatatccg atttatactt tgtataaaga
      301 actaaagtag ttagcaaatc atttacagca aatcactatg ttccacatac cattttacat
      361 acttacctta tccacgacac atgttgagat agtatcgaag ataaagaaag ttgctccatg
      421 ttgtttttgc gagatgggga aatcaaagcc acattgacaa ccatgatgaa taagcttgct
      481 ttcagtcata agctaatcct agaaccactt ttcaagtcag ttagccaaat cgatgaagaa
      541 agcgaccgtg aaagaatgga cgctattgat aagctaatgg agcaactatt ggaagaacgc
      601 aataccctta ttgcactgat gtccaaaggt ttcctagaac ctgctctttt taatcaggaa
      661 cgaaatgttt tagatagtga gattaaaaat cttactaccg aaaaaacaaa cctggtaacg
      721 aactctgcga gtggggtttt gcgagcaaac gagataaagg acctcattaa ttatgtgtca
      781 gcagataatt ttaatggtga ctacacggaa gaactatttg aagaatttgt agtgaacatc
      841 attgtaaatt ccagggatga gctgacattc aatttgaaat gcggtctttc cctgaaagaa
      901 aaggtggtga gataaatggc atatattcca tatggataca aaattcaaga tggagtggtt
      961 actgtcgatg aaaaggcagc aggtcaagta aaggtattct ttgagaaata catatcagga
     1021 ctatccctta cagtggctgg cgaacaggca ggtattgaaa agacacattc tgtgatgggg
     1081 cgcattttga aaaacgtcaa ctaccttgga aatgatacgt atccagcaat tattgataaa
     1141 gagatatttg ataaagctga agaagttaga gataaacgtg caaaggattt aggacgagtg
     1201 gtagagcttg ccgctttcac ctctccccct cccaaagaac gattcaaaat gaaaaaggca
     1261 gataataaga tgccagtgga tccttttgaa cgagcagaat acttatacag tctgatagaa
     1321 agcgaggaat aaagtgacag agaaaaatat aatggttatt cctgctcgta aaagagtagg
     1381 aagtacagcc gcaaaagaaa agataaagaa acttcgtgtt gctgcctatt gccgtgtttc
     1441 tacagaaaca gaagaacaaa attctagcta tgaggttcag gtctcacact atacagagtt
     1501 tataaagaaa aataatgaat gggagtttgc tggcatcttt gcagatgatg gtatctctgg
     1561 tacgaacact aaaaagcgtg acgaatttaa tcgcatgatt gcagagtgta tggacggtaa
     1621 catcgacatg gttattacaa aatccatcag ccgatttgcg cgtaacaccc tagactgcct
     1681 tcaatacatt agacagctca aggataagaa catatcagtt tattttgaga aagagaacat
     1741 caacaccacg gatgccaaag gtgaggtttt gctgactatt atggcatctt tggcacagca
     1801 ggaaagccag agcctttcac aaaacgttaa gcttgggcta cagtaccgat accaacaagg
     1861 aaaggtgcag gtcaaccata agcgatttat gggctacacg aaagatgaag atggaaattt
     1921 aactattgtc cccgaagaag ctgagattat caaacgcatc taccgagaat accttgaggg
     1981 tcagagtcta gtgggcattg gtcgagccct tgaaaaggat ggtattttaa cagcagcggg
     2041 aaaaccaaga tggcgaccag aatcagttaa gaagatactt caaaacgaaa aatacatcgg
     2101 agatgccctt ctgcaaaaga ctgtcacagt agattttctg accaagaaac gagtgaaaaa
     2161 tgaagggcat gttccccaat attatgttga aaatagccat gaagcgatta ttcctaaaga
     2221 gttatttttg caggcgcaag aagaaattca tcggagaagc aatatctaca caggagaagg
     2281 caagaacaaa agaatttaca gtagcaagta cgctttaagt gccatcacct tctgtggaga
     2341 ttgtggcgat atttatagac gggtctattg gaatatccac ggaagaaaag aatttgtctg
     2401 gcgatgcgtg actagaatcg agcaaggtcc tgaagtttgt aagaaccgaa ccgtaaaaga
     2461 agatgaactt tatggtgcag taatgactgc gattaataag ctacttgcag gtgggaacaa
     2521 tatgataaag acactggaag agaatattca tgctgtgatt ggcgaaacca cagaatacca
     2581 aatttcagag attaacaact cactagagga aaaacaaaaa gaactaatca agctggcgaa
     2641 caagggtcaa gactatgacc acttagcaga tgagattgat gagctgagag acaagcgaca
     2701 gatcctttta gtagaagatg cctccctcag tggcgagaac gagcgaatca atgagctgat
     2761 tgaatttatc cgcaagaaca aattccgcac cttagaatat gatgataagc ttgtaaggaa
     2821 gataatccag agcgttacag tctatgaagg ccacttcgtc atagccttca aatctggcat
     2881 cgaaatggaa atatgaaaac cagaagtaaa tagcccatga ctctacagta gagttgtggg
     2941 ttttcttttg cttgctgatt ataataatat tttaataact attgtgttta tcaaccaaat
     3001 ggtttataat attcttagcg taaacttgga ggtgctgtat gactacggca gaaatgatta
     3061 aagaactgtg tgagcaaatg aatataagtg tttccgaact tgctagacgt attggccaga
     3121 ctccacagaa tttcaataaa aaattacaac gagaaacagt aaccttggat gagttgaagg
     3181 ccattgctga tgtgctaggt gtcaagtttg tgcaggcatt tattttacca gatggagaag
     3241 aaataaaaat atctaacgaa taaaggagga tgtttatatg gtaggtaatg ttattcaaat
     3301 agtaacagag aaattatcat ctttgccttt tatagaaggc atcgtattag ggggctcacg
     3361 tgcaagaggc acccatacag aaaattctga tatagatatc ggaatctatt acaattcaga
     3421 ctcatttgac ctgacagcga ttaatcaaat tgctacagaa ttggatgata aaaatagaaa
     3481 caaccttgtt gtgcctcccg gagcgtgggg tgattggatt aatggcggcg gatggttatt
     3541 tataaatggg tatcatgttg acttgatttt acgtgatata aaacgggtag aacaaataat
     3601 caaagatacg gagcaaggaa ttgttactgc caattatcag accgggcatc cccatggtta
     3661 tataagtgca atgtatcgtg gagaattagc gattagtaaa atactatatg ctaagaacga
     3721 aagcttatgc gaattaaaaa agcaggcaga aatttaccct actgctctaa agaaaagctt
     3781 gatgaacttt tttatatttg aagctgaatt ctctttaatg tttgtaaaag caaatgcggg
     3841 ggtagaggat aaatattata ttgcaggcca tgtttttcgt attatttcat gcttaaatca
     3901 agtactattt gcatgtaata atgcttattg cattaacgaa aagaaagcta taaaactgct
     3961 tgaaactttt gaatataaac ctgaaaaata tgccgaaaga gttaatcata tttttgaagt
     4021 actcggtctt tctctttttg aatgctacga tatgaccgag aaactttata aagaagtgaa
     4081 tgaaattgta tcggagataa ataacttttt aaacgaggag agttcagatg aaagaaaaca
     4141 aatatgatga taatatattt tttcaaaaat acagtcaaat gagtcgctcg cagaaaggac
     4201 tggctggtgc gggagaatgg gagactttga aaaagatgct acctgatttt aagggtaagc
     4261 gtgtgcttga tttaggatgc ggctatggat ggcactgtat atatgcgatg gaaaacggtg
     4321 cttcctctgt agtaggtgtt gatatttctc ataaaatgct cgaagtagca aaaggaaaaa
     4381 cccattttcc acagattgaa tatgaatgct gtgccataga agatgtggat ttcccagagg
     4441 agagctttga tgtaatacta agttcgcttg cgtttcatta tgtagcagac tatgagaatt
     4501 taataaaaaa gatatatagg atgctgaagg ctggtggcaa tttagttttt acagttgaac
     4561 atcctgtttt tactgctcat ggaacacaag actggtatta taacgaaaaa ggagaaatac
     4621 tgcatttccc ggtggacaat tattattatg agggcaaacg gacagctatg tttttggaag
     4681 aaaaggttac aaaatatcat agaacactga ccacatatct aaatacactg ctttcaaata
     4741 gttttataat aaatcagatt gtggagccac agccgccaga gaacatgatg gatattccgg
     4801 ggatggcgga tgaaatgcga cgcccaatga tgctgattgt atcggcaaaa aagaagatgt
     4861 aataatatag aaaaaataaa cgaggagtat gtaaatgaga tcagaaaaag aaatgatgga
     4921 tttagtactt tctttagcag aacaggatga acgtattcga attgtgaccc ttgaggggtc
     4981 acgcgcaaat attaatatac ctaaagatga atttcaggat tatgatatta catattttgt
     5041 aagtgatata gaaccgttta tatctaatga tgactggctt aatcaatttg ggaatataat
     5101 aatgatgcaa aagccggagg atatggaatt attcccacct gaagaaaagg gattttccta
     5161 tcttatgcta tttgatgatt acaataaaat tgatcttacc ttattgccct tggaagagtt
     5221 agataattac ctaaagggcg ataaattaat aaaggttcta attgataaag attgtagaat
     5281 taaaagggac atagttccga ctgatataga ttatcatgta agaaagccaa gcgcaaggga
     5341 gtatgatgat tgctgcaatg aattttggaa tgtaacacct tatgttatta aaggattgtg
     5401 ccgtaaggaa attttatttg ctattgatca ttttaatcag attgttcgcc atgagctgct
     5461 gagaatgata tcatggaagg tcggcatcga aacaggcttt aaattaagtg taggcaagaa
     5521 ctataagttt attgaaaggt atatatccga ggatttgtgg gagaaacttt tgtccaccta
     5581 ccggatggat tcctatgaaa acatatggga agcattattt ctatgccatc aattgttcag
     5641 ggcggtatcc ggtgaggtgg cggaaaggct tcattatgcc tatccggagt atgataggaa
     5701 tataacaaaa tataccaggg acatgtataa aaaatacact ggtaaaaccg gctgcctgga
     5761 tagcacatat gccgctgata tagaagagag gcgggaacag tgattacaga aatgaaagca
     5821 gggcacctga aagatatcga taaacccagc gaaccatttg aggtgatagg taagattata
     5881 ccgaggtatg aaaacgagaa ttggaccttt acagaattac tctatgaagc gccatattta
     5941 aaaagctacc aagacgaaga ggatgaagag gatgaggagg cagattgcct tgaatatatt
     6001 gacaatactg ataagataat atatctttac taccaagacg ataaatgcgt cggaaaagtt
     6061 aaactgcgaa aaaattggaa ccggtacgct tatatagaag atatcgccgt atgtaaggat
     6121 ttcagggggc aaggcatagg cagcgcgctt atcaatatat ctatagaatg ggcaaagcat
     6181 aaaaacttgc atggactaat gcttgaaacc caggacaata accttatagc ttgtaaattc
     6241 tatcataatt gtggtttcaa aatcggctcc gtcgatacta tgttatacgc caactttgaa
     6301 aacaactttg aaaaagctgt tttctggtat ttaaggtttt agaatgcaag gaacagtgaa
     6361 ttggagttcg tcttgttata attagcttct tggggtatct ttaaatactg tagaaaagag
     6421 gaaggaaata ataaatggct aaaatgagaa tatcaccgga attgaaaaaa ctgatcgaaa
     6481 aataccgctg cgtaaaagat acggaaggaa tgtctcctgc taaggtatat aagctggtgg
     6541 gagaaaatga aaacctatat ttaaaaatga cggacagccg gtataaaggg accacctatg
     6601 atgtggaacg ggaaaaggac atgatgctat ggctggaagg aaagctgcct gttccaaagg
     6661 tcctgcactt tgaacggcat gatggctgga gcaatctgct catgagtgag gccgatggcg
     6721 tcctttgctc ggaagagtat gaagatgaac aaagccctga aaagattatc gagctgtatg
     6781 cggagtgcat caggctcttt cactccatcg acatatcgga ttgtccctat acgaatagct
     6841 tagacagccg cttagccgaa ttggattact tactgaataa cgatctggcc gatgtggatt
     6901 gcgaaaactg ggaagaagac actccattta aagatccgcg cgagctgtat gattttttaa
     6961 agacggaaaa gcccgaagag gaacttgtct tttcccacgg cgacctggga gacagcaaca
     7021 tctttgtgaa agatggcaaa gtaagtggct ttattgatct tgggagaagc ggcagggcgg
     7081 acaagtggta tgacattgcc ttctgcgtcc ggtcgatcag ggaggatatc ggggaagaac
     7141 agtatgtcga gctatttttt gacttactgg ggatcaagcc tgattgggag aaaataaaat
     7201 attatatttt actggatgaa ttgttttagt acctagattt agat
//
LOCUS       DAXLPQ010000087         6905 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.090, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000087 DAXLPQ010000000
VERSION     DAXLPQ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.090"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..173
                     /locus_tag="ACF3UO_002563"
     CDS             <1..173
                     /locus_tag="ACF3UO_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HFD3658502.1"
                     /translation="RNIFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLF
                     ATLLNYSIYFLN"
     gene            complement(281..1507)
                     /locus_tag="ACF3UO_002564"
     CDS             complement(281..1507)
                     /locus_tag="ACF3UO_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3658503.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(2261..2461)
                     /locus_tag="ACF3UO_002565"
     CDS             complement(2261..2461)
                     /locus_tag="ACF3UO_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3658504.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(2595..3203)
                     /locus_tag="ACF3UO_002566"
     CDS             complement(2595..3203)
                     /locus_tag="ACF3UO_002566"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFD3658505.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(3288..3758)
                     /locus_tag="ACF3UO_002567"
     CDS             complement(3288..3758)
                     /locus_tag="ACF3UO_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFD3658506.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(3806..4720)
                     /locus_tag="ACF3UO_002568"
     CDS             complement(3806..4720)
                     /locus_tag="ACF3UO_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3658507.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            4866..5669
                     /locus_tag="ACF3UO_002569"
     CDS             4866..5669
                     /locus_tag="ACF3UO_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFD3658508.1"
                     /translation="MTTKQLIISSFIRFKDLKETRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKELR
                     SFLSKASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            5847..6794
                     /locus_tag="ACF3UO_002570"
     CDS             5847..6794
                     /locus_tag="ACF3UO_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFD3658509.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         2149 a         1368 c         1047 g         2341 t
ORIGIN      
        1 taagaaatat tttcattgca gcaatcgata ttacactttt agttattttc ttgtcagtgc
       61 ttatgtatca gttgtggcta catcatcgcc tggcaatgtg gctcatgatt ccttattatt
      121 tatgggtact attcgcaact ctattgaatt attcaattta ttttttaaac taagcgctaa
      181 aaagagacgt cctgtaattt aacacataga aaaagtgcca cctaagttag attttttgtc
      241 taatttaggt ggcactcttt attaaccaaa ctattttttt ctagtaccca cttgttgttc
      301 catactcatt attctggtca taaccataac cattttgttc ctgtccagcg taaggatcat
      361 aactttgagt atcttgactt ggtgtatagt actgacttgt atcttctgtt tgctgataat
      421 aggtattcgg atcttggtac tgatcatatg tgttttctga ataggaagaa taatcggtgt
      481 acccttcact attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa tcatcaaaga
      541 acatcattga agcattctca tttttcaaat taggtaatgt atcgcttgtt tttatattta
      601 attgtttctt cagttcattt tggatcgaaa gaagatcatt ttttcctaaa atttgatagt
      661 agatatcatt gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt gtttcaaacg
      721 caggggtgta gttcgtcgct acatcaagca tgtcatccca atctaagtcc gtcgtcacat
      781 tgttctcaac tgcttttaaa atttttctat aattgcttac gccatctaaa cttaaaactt
      841 tattgacgat tttcgtcact acttcccgct gacgacgttg tcgaccgata tcgccttctg
      901 gatcttcgtg tcgcattcga gaataggcta aacctttttc tccattcaat gtttgttcac
      961 ctactggtac atggacacca tccaaagtaa agtcaatttt attattcact ttgatgccac
     1021 cgaccgcatt gatcaaatct tccatgccat ccaaattgat cgttacataa tgatcaatag
     1081 gaatatcgag cagttgctca attgaatcca tggccatttc gacaccacca aatgcatagg
     1141 catgatttaa tttatctacc gttccataac ctacgatatt cgtataaata tctcggtcca
     1201 aactgatgat cgttgatttt ttttgtttcg gattaactgt tactaccatc atcgtatcag
     1261 aacgtccttg ttccgttctt cctaatccac cggtatctaa acctaatagc aaaaccgaaa
     1321 aaggttcttt gtcatcaatg cttactctct cagaacgttt ggaggatatt cgattagagt
     1381 ttttagaaat tttgtttact gtttggctcg cttctcccat aaatctgatt ccgtatgctg
     1441 ataatccggc aatcagcaaa acaaataccc ctaacaaggt taatagaact ttttgccatc
     1501 gcttcataat acacctctgt ttcacatttt ctaaaatatt gtctcatata actgttcaat
     1561 cagcaaattc actttttaat cataagaaaa ctttaaaaaa catttttgtg taacgattac
     1621 tattttttaa aatttctcaa aattcttaac tatcatacca taccgtgaaa aagatcgaaa
     1681 gaccgaatac acgcagttcg caatcgtttt atcttttttt acgtattttt tccagaaaaa
     1741 gcgaacaaca aggtattttc caaataatcg tgcagtaaaa tgatcgcaca tacctttccc
     1801 atctttttaa cagtctttgc ctaccgttca gattatcatt cgatttcacg aaaatttctt
     1861 cctatgactg gtccttttgt taaacccatc ttctattcgt tttatttcca gctcactgca
     1921 tggctcttaa aatgactcga actagtgatt tcattaccat catcttttaa tggatagata
     1981 tgctcctctt caaagtaaaa cgattttctt ttaaagtaat agaattgaca tggtaatgag
     2041 tatgtatact agtggtttca caaatggtct tttattcaac atccaaaaac tgaaatttct
     2101 ttaaaatcca ttactaacga agaaaatgtt ccttgcttga taattagtta ggacatgtca
     2161 agtgaacaaa tgcatttact tagccaaaaa atctaaaaac ttcataaata gacaaaaaga
     2221 cacgactctc taagaagtcg tgtctttatt caacaaatta ttataattta gtcacttcag
     2281 cagcttgagg tccgcgtgca ccttcaacaa tcgtgaattc tacttcttga ccttcttcta
     2341 ggctcttgaa gccgtctcct tgaattgctg agaaatgaac aaatacgtca tctccgccgt
     2401 ctactgtaat aaacccaaat cctttttcat tgttgaacca tttaaccgtt ccgtgttcca
     2461 taaatgtata gcctccaaaa aagttcttgc aagtaacctt gcaagaacat tatacccaat
     2521 ttagaaaacg ctagcaagct ttcgctcttt tattttccaa attattttta agactgatat
     2581 gacggaggaa atggttattt tgctgcttcg aaacgtttgt ttacttcatc ccaattaata
     2641 acattccaga atgctgcaat ataatctggt cggacatttt tatatttcaa ataataagca
     2701 tgttcccaaa cgtccaaacc tagaattggt gtctttcctt ccatcaatgg agaatcttga
     2761 tttgcagtag aggtaatagc taattttcca ttttccatta caagccaagc ccatccagaa
     2821 ccaaatcgtc cagcggctgc ttttttgaat tcttctttaa aagaagaaaa atcaccaaaa
     2881 gcttcattaa tcgcttcttt tatttctcct gtaggttcgc caccagcatt tggtgccatg
     2941 atttcccaga aaaatgaatg gttagcatgt ccgccaccat tgttacgtac agctgtcttg
     3001 atatctgttg gaatagcgtc catatcagat aataattctt ctattgtttt ttcgcctaat
     3061 tctgggtatt tctcaattgc tgcatttaaa ttcgtcacat aagtattgtg atgcttatca
     3121 tgatgcagat gcatcgtttc ttcgtcaata taaggttcca atgcgtcata tgcataaggt
     3181 agatctggta atgtgtaagt cataaaaaaa ttcctcctca atgttttctt tataatgtct
     3241 acattacaaa gagtaacaaa gagaaggaaa ttcttcaatt gttatgccta gtcgtctttt
     3301 tcactttgac ctacttcttc ttcaaaaacc tcagtttctt taaaaataaa caacttgctg
     3361 aaaatatagt tcgctaggat aacaataatt tgagtgatga ttttcgccac atactcattg
     3421 ctgttcataa cattgatcaa caataccatt gcccccatgt ccaatccgta agaaaggata
     3481 cggtagaaga agaacttacc gcattcaata agtgcatgtg taaaattcgg tgattttgaa
     3541 tggaataccc aaagtttgtt cgttacaaaa gcaaacaata cagaacaaaa ccacgaaata
     3601 gaattggata aggccatact taaatcaaaa tattggcgtg cgagagcaaa actaacaaaa
     3661 tttacaatcg tagccaaacc accaaaaaag agatagacta gtatctccca atatcctttt
     3721 gcttctaaat atccttttaa ctgtcgatac tgcttcatga gccaacctac cttattaaaa
     3781 attcttattt atcatactct atatttcaat aactttcatc tttatttaaa aaaattaatt
     3841 ttttttgatc ctttgccttt gtctctgctt ggatcgtcac atgtgtaata ccatatttta
     3901 attttaataa agaaattata cgaggatata tcttttcaat ctcgcttagt agctgatctt
     3961 caaaatcaat atgtccgtcg aaaataatta tcttttcgct atactgccaa atatggacat
     4021 gatgaacatt ctttacccca tcgattgctt caatttcttg ttccattttt tcatagtcaa
     4081 tagcaggtgc actttgtatc aaaatagcgg cagctttttt gatcaccatt atcgcttcta
     4141 tcaatatata tatcgaaatg atcagtgtaa taactggatc gatccagtag atatcgaaaa
     4201 aacggatcaa aattgctccg ataatcacac ttaccgaaga cagtgtatca cttaacaaat
     4261 gcaaataact agattttata ttcaaacttt catctgcttc ttgtcgtaat aataatactg
     4321 agaacaaatt cgcgagcaat ccaataactg ctactgttag catcaaatga ctatttatct
     4381 tttctggtga agtgaaccgc ttgaatgctt caacggttaa aaacaaggat aatatgatca
     4441 atatgaatga gttgatgaaa gcactcaata tttctaaacg ctggtagcca tacgtacgtt
     4501 ttttatttgc ttcttttcgg gccatttttt gtgccccgta agaaaaaata attgccaatg
     4561 tatcactaag gttatggaaa gcatctgaaa caagagacaa actccctgac ataatccctc
     4621 caataaattc tgataaagtg atcaccgcat tcaaaaccac tactccaaat agtttttttg
     4681 atgatctctg tggctgtgta ggcactattc cttcctccat tttatttata ttggatagtc
     4741 tttagacaag aataacattt ttttgatatt tcaccaatca ttcagatgtt tccctaaagc
     4801 acttgtattt cacttgatac ttcgctagaa ttgcaagtga tgacactact agatgaggag
     4861 tacttatgac aacaaaacaa ttaattatca gttcctttat acgattcaaa gacctaaagg
     4921 agacgagaaa tgtcccattt tggaaagcca ttgtctatct tttagttttg agtataatta
     4981 tggctttgcc aatctctttt caagtttttc aagtcttaaa caacattcaa ttggatgggc
     5041 aaaagattgc tactcgcatt cctgatttta caatccaaaa cgggcagctt caaaccgaag
     5101 aaaaagaagg attcatttac caaacaaact ccattatctt cacatttgat ccagagggaa
     5161 aacgaacaga acaggacatc tctactgatt tgatggggaa ttttgttagt gtcgggatgt
     5221 taaaaaacaa acttatcata gctcttccta atacaggcac gacttctgct ttgttgaaca
     5281 ataaccaatt agaacttccc tacaccaatg aatctttaaa aaacttaaca ggtaaggagc
     5341 tccgttcttt tttaagtaaa gcatctatac cactttggat aaaagtcctg acatttatat
     5401 tttctattta tcctagtttt ctgaatctgc tgatcacttt gctatttacc aacattgctg
     5461 cttttctcta tgcacgcttt cgactaacaa aagctacttt tcttgattgt ttaaaaacat
     5521 tgatctattc aatttcattg cctactataa ttgcaacaat cttgatggtc tttcttcctt
     5581 cttttgacac aagcgccttc attgcttttg caggaatctt tatttttgct caagctgtca
     5641 aaggatgggc aaaaatatcg atcaattaag aaataaagac aactcgttat ttctacttca
     5701 atagaccctt ttagaggttg tgacattttt ttgtcacagc ccctttttta tttgaaaaat
     5761 atttctttct caaaaaacaa gcaaggcgct tcaaagttct tcttgtatgc gctacactta
     5821 gagtaaagaa aggcgggaaa ttaactatgt cagaaagaat catttatgca gatcgtccat
     5881 ttcgtgatga atttatcgaa gaaatccata ctatagcgcc tggttatatc tttaaaacag
     5941 aattacaacc agaggatcta caaaatgtag agatcagttt gggctggaac tcagactacc
     6001 aagaaaaact attagcctct tctaccttga aatgggtcca atctatctca gctggtgttg
     6061 atcagctacc ccttgagact ttttcaaaga aacatatttt actttcaaat ggtagtggca
     6121 tccacagtga atcgattacg gagcatgtct taggaatcat ccttgggtat tctcgtggtc
     6181 tttttcaagc acaaaaagca cagagtgaca tgaaatggtt aggttcatcg gtccattacc
     6241 aatctatcca aggaaaaaaa atactaatca ttggaactgg ccatattgga aaaatgattg
     6301 caaaaaaatg caaagcatta gacatgaact gctatggaat caatacatcc ggtcatccag
     6361 cagaaggaat ggaaaagact ttttctttaa atcaactaaa ggaagttctt cctgaagtag
     6421 atttcgtagt caatatctta cctctaacgg aggaaacaac tgggctcttt gatcagcata
     6481 tgtttgaaca ctttgatcca aaatctgtat tcatcaatgt tggccgtggt gcttctgtta
     6541 agacacaaga tctggtgcag gctttaaata accagcaact ttcctttgca gcattagacg
     6601 tttttgagga agagcctctt ccacaagatc atcctctttg gaaaatggac aatgtactga
     6661 ttacttccca cattgcaggt ttgacacctg attttcaaaa gaaattaatg gctatttttt
     6721 taaccaatct gaaaagctac tttgccaccc atgagcttca aaccaatcaa gtaaaattgt
     6781 ctgcaggata ttaatagctg aaaacaatat tttcaaaaga acaaagagaa ggtgacaaaa
     6841 ctggctctat aatttatggg actgatgaat cagaattgat tcttcagccc catttttatt
     6901 ttagg
//
LOCUS       DAXLPQ010000088         6604 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.091, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000088 DAXLPQ010000000
VERSION     DAXLPQ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.091"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            374..973
                     /locus_tag="ACF3UO_002571"
     CDS             374..973
                     /locus_tag="ACF3UO_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3658510.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLSDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQVHDFSKYLFPSRKLADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            1022..1492
                     /locus_tag="ACF3UO_002572"
                     /pseudo
     CDS             1022..1492
                     /locus_tag="ACF3UO_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405176.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1706..1969
                     /locus_tag="ACF3UO_002573"
     CDS             1706..1969
                     /locus_tag="ACF3UO_002573"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658511.1"
                     /translation="MKQIQNDLYGNIEKEYFDSQMFQQNSSPYYSEERFFQLMEQEEE
                     KRLLQLMKEMEEQQVAEEIEEKRFIKLIEEQMEIESLREQEEE"
     gene            2117..4219
                     /locus_tag="ACF3UO_002574"
     CDS             2117..4219
                     /locus_tag="ACF3UO_002574"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HFD3658512.1"
                     /translation="MMTTQDLMDKYEVSRQTVNNWVRKNEIPAPTVKKGHQNAWTFSQ
                     AELIDKKLKHSHSEQLELFKTESTPLHINNRRYLGSKQKILDFINDVVSEHTKNVKSV
                     ADVFGGTGVVANLFNKQGKKVIVNDILTSNYISYETWFGNMPVDEKKIQFKIEELNSL
                     EGIHGYVDKNFGNKYFSVENAQKIDAVREKIETYNDLNEREKAFLLTSLLYAMDKVAN
                     TVGHFDAYRKKMDTFKPIYLRVPEFNKNVGNEIYNEDANQLVRKIKTDLVYIDTPYNS
                     RGYESAYHVLENVMEWKKPDVEGVAMKAVNRSEKSSDYTKSKAPQAFDDLIQNINARY
                     ILVSYNNMAKKGNSRSNAKISNEEIIATLKKRGQVEVFSIDFNAFTTGKSNIENHKEL
                     LYLCTVDDEIIQSPLNYTGGKQKLIPQLRPYFPSRYTRLIDLFSGGGSVTANLAKNGQ
                     AESYLMNDVENHVINFFEYISTIDIDDFINQAEMKISEYGLSNTKKNGYEFYSANSAS
                     GLGAYNKEKFLKLRKDYNNSPSPLLFYLLVVFGFNNQIRFNSKGEYNLPVGKRDFNKK
                     MEEKLRKFVKVIQDSPIEYSTKDFREVSIDTGDFIYADPPYLITTAAYNENGGWSEKD
                     EKDLYDYLDKANENNIKFALSNVIIHNGRENEILKSWASKYNLYVLNYNYNNSNYQSK
                     AKQSETVEVLVTNYERDI"
     gene            4219..6174
                     /locus_tag="ACF3UO_002575"
     CDS             4219..6174
                     /locus_tag="ACF3UO_002575"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF021040.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HFD3658513.1"
                     /translation="MKLTNTAETFNLGDTSFRRKTLIDDYKTLLPYLQETNLEFNEWN
                     NVAQAEFYEKILTKTDLFSRNTDEDFAKRGRTLTNALVKIGLTNSKRKLSRVANSWIN
                     ENTLSANDVERSLGIDANNLLFTRQLLKLRVYDSNKMNYFYPFRVALGLVIKYQNIPQ
                     QDFLTLIHLIQPSFDNRKIKDIINDYHSVNDNNEIFSEFLDRNFPENTSELTADELFS
                     KKPLNRKEFDSLFVNRKSSATQGIYFEFVNKLLAFKSNKNVENLDALLELNSNDKLTK
                     AFGFGKAIFAKTNFMKSKNIQDFLDENVDNDLLSENNTLIYNQFVLSKKDDIVREYRD
                     MTKRTFNLSGLLDFNTGLVNATNQDVLSIIFSSMSFSGTENYADYEENLSYSFYQEST
                     ITEVLDLDESAILSEIKAFLGIENTSQIESVVLTQKEDKFRKFISKTFPREKIIEILP
                     LFSPRDDKKIKSEVSESATVPTIYEYIVAIAWFYISKEEFFITKSLNLTLDGEMRPLS
                     HAAGGAGDIVIDYENLTLMLEVTLMNAQAQKRGEWEPVLRHATNLTVDNFDKNVITLF
                     IADELDDNTVNIWRAVASVPLRSSNKDEIADLVKIFPLENRELLHMLKNNLDERKLLK
                     AIDESYEELAGNFDLSWRDKIFVEANM"
BASE COUNT         2398 a          956 c         1235 g         2015 t
ORIGIN      
        1 gattcatcgt cattcctcct gctatctttt tctattattc taccttattt gatagtagat
       61 ttaaaacttt gcaacagaac cgttaattat atagactgaa aattttgaat tttcagaata
      121 gaacaactta aaagtactga caaaattttt taaaggggca atattaatgt tctgagataa
      181 tcaaatctta ccgaaaatct caaaagtcca atgtgacaca agctgattct gtcacattcg
      241 ttaaaatcgc tccatcctta gaggctctaa gaggaaatca cttttctttt agggcctttt
      301 ttctatagct tgtttaaatg tgacttatta tctgttataa tcatattaag taacatttga
      361 gaggggacta aaaatgaaga gcgtggaacc gattcgcgac aaaaaaaaga tcgatgccat
      421 gaaggccatt ttggcttccg gaaaatatgg gcaacgaaat ttggtgcttt tttcaatcgg
      481 gatcaataca gcctatcgaa tctccgattt aaggcagttg aaattaagtg atgtgttaga
      541 aatttcccgt gggcgggtga ttgtcaaaga acgtctggcc atgaaggaac aaaaaacggc
      601 caaacataat tcggtcttca tttcaaacaa attacgaaaa gtgattctcg attatgtcca
      661 atccgaattt cctgagcagc tgcaagtaca tgacttcagc aaatatttgt ttccaagtcg
      721 aaaattagca gatacgcctt tgacccgaca aagcctttgg cggatcattc atgaagcagg
      781 aacagcggtt ggtttaaaag aaattggtcc ccattcgatg cgcaagacct tcggctattt
      841 tttgtacaag caagggacca aaacagagat cattcagtcg ctgctcaacc attcttcgca
      901 acgggagacc ttacgctata ttgggatcac ccaggaagat aaagataccg cagtaaagag
      961 tttggatctg tgacagaata atgccctata taatagaaga aaaaattcaa gaggggagaa
     1021 gatgaacgaa gaaaagcgtc cgaaatttcc tgataaatac cacttatctc gcaaagagtc
     1081 tgtgtattta ttgaagaaaa acattgtgga actggtgtat aatgcgggaa aatttgaagg
     1141 gttaaataca acgctattac aaacagaaga gattatcaag tataatcgag ctaataatat
     1201 ggcggtagat gatgtcctga ccgtcgttaa cttaaaaaga ggctttgaaa tgcttttaaa
     1261 cgacttacag gagcccctaa tagagacaag taagcggatt aatcggatcg ttgcagcaga
     1321 ggatgcgctt ttttccggtg aaatacgaac tggtggggta gaagtatcga cgattcaagg
     1381 aagatatgtg ccaccaatgt taactgaaga cgaggtaaac aatcaatatg gtgagataat
     1441 gaataaagag atatcagata cggaaaaagc cctgcgactg tttctattca tttaatgcaa
     1501 taggagcggg tatttgtaat gcttcccata gtgccacccc atttttgaaa tcaatttccc
     1561 acgtttcttc gttctcgcca ttctttggga gaagctcaag agatggcgga gtaaaatcaa
     1621 attcgctttt cattatatta attgtctaac ttaatttgac aattaatatt atttatacag
     1681 cacaagtgag aaatatattg aacagttgaa acaaatacaa aacgatttgt acggtaacat
     1741 tgagaaagaa tattttgata gtcaaatgtt ccaacaaaat tctagcccct attattctga
     1801 agaacgtttt tttcaattaa tggaacagga ggaagaaaaa agactacttc aattaatgaa
     1861 agaaatggaa gaacaacaag tagcggaaga aatagaagag aaacggttta ttaaattaat
     1921 agaagagcaa atggaaatag aaagtttaag agaacaagaa gaagagtaag ttctgcgttt
     1981 gttagaaaca taatatcttt gaaaacaatt tagacaaacg acaggaaatg gtaatttgaa
     2041 aactaaacat tgataattac ttattgcact taatatggta gaattgcatt aactgtaaag
     2101 agagggtgat gcctaaatga tgacaacaca agatttaatg gacaagtacg aagtatcacg
     2161 acaaactgta aacaattggg ttcggaaaaa cgaaattcct gcacccacag taaaaaaagg
     2221 gcatcagaat gcttggacat ttagtcaagc ggaacttatt gacaaaaaat tgaagcatag
     2281 tcacagcgaa caattggagt tgtttaaaac tgaatcgact cctcttcata tcaataatag
     2341 aagatattta ggcagtaaac agaaaatact agattttatc aatgatgttg tttcggaaca
     2401 caccaaaaat gttaagtcag ttgctgatgt ttttggtgga acaggtgttg ttgctaattt
     2461 atttaacaag caaggcaaaa aagtcatagt taacgatatt cttacaagca actacatttc
     2521 ttatgaaaca tggttcggga atatgcccgt agatgaaaaa aagattcagt tcaaaattga
     2581 agaactgaat tctcttgaag gtatacatgg atatgttgat aaaaattttg gtaataaata
     2641 tttttcagtt gaaaacgcac aaaaaattga tgcagtccgt gaaaagatcg agacttacaa
     2701 cgatttaaac gaacgtgaga aagcattttt gttaacgtct ttgctatatg ctatggataa
     2761 ggtggctaac acagtaggac attttgatgc atatcggaaa aaaatggata cctttaaacc
     2821 tatttattta cgagttcccg aattcaataa aaatgttgga aatgaaattt acaatgaaga
     2881 tgctaatcag ctagttagaa aaattaaaac agaccttgtt tacattgata caccttataa
     2941 ttctcggggc tatgaaagtg cttatcatgt tttagaaaac gttatggaat ggaaaaagcc
     3001 ggacgttgag ggagtggcaa tgaaagcggt caaccgctct gaaaaatctt cggactatac
     3061 taaatctaaa gcaccccaag catttgatga tttgattcaa aatattaacg ctcgatatat
     3121 tttagtttcg tacaataata tggcgaaaaa aggaaattca cgttcaaacg caaagatttc
     3181 aaatgaagaa attattgcca cattgaagaa acgtgggcag gtagaagttt tttcaattga
     3241 ttttaatgct tttacaacgg gcaagtcgaa tatagaaaat cataaagaat tactgtatct
     3301 ttgcacagtt gatgatgaaa taattcaatc gccactgaat tatacgggcg ggaaacaaaa
     3361 attgattcca caattacgac catattttcc ttcaaggtat acacgattga ttgacttatt
     3421 ttctggtggt ggtagcgtta ctgcaaatct ggcaaaaaat ggacaagcag aaagttatct
     3481 tatgaatgat gttgaaaatc atgtgattaa tttttttgag tatatttcaa ctattgatat
     3541 agatgatttc attaaccaag cggaaatgaa aataagtgaa tatgggttat ctaatacgaa
     3601 aaaaaatgga tatgaattct attctgcgaa tagtgctagt ggtttaggtg catacaataa
     3661 agaaaaattt ctgaagctaa ggaaagatta taataattca ccgtcaccat tgctatttta
     3721 cttgttagtt gttttcggtt ttaataatca gattcgcttt aattcaaagg gtgaatataa
     3781 tcttccagtt ggtaaacgag actttaacaa aaagatggag gaaaaattac gtaagtttgt
     3841 aaaagtaata caggactcac caattgaata ttccaccaaa gatttccgag aagtgagtat
     3901 agacacagga gatttcatct atgctgatcc gccgtatctt attacgacgg cagcttacaa
     3961 tgaaaatggt ggttggtctg aaaaagatga aaaagactta tacgattatc tagataaagc
     4021 aaatgaaaat aatattaagt ttgctctttc aaatgtgata attcataacg gaagagaaaa
     4081 tgaaatcctt aaaagttggg cttcaaaata taatttgtac gtcttaaact ataattacaa
     4141 taatagcaac tatcagtcca aggctaaaca aagtgaaaca gttgaagttt tagtcacaaa
     4201 ttacgagagg gatatttaat gaagcttaca aataccgcag aaacatttaa tctaggtgac
     4261 acaagtttta gaagaaaaac attaattgac gactataaaa ctttgttgcc ttatcttcaa
     4321 gaaacaaatc tagaattcaa tgaatggaat aatgtcgcgc aagcagaatt ttacgaaaaa
     4381 attttgacaa aaacagattt attttctagg aatactgatg aggattttgc aaaacgtggg
     4441 agaaccttaa ccaatgcctt agttaaaatt gggctaacaa attcaaaaag gaaactttca
     4501 agagttgcta atagttggat aaatgaaaat acgcttagtg caaatgatgt tgaacgttca
     4561 ctaggaattg atgcgaataa tttattattc actcgtcagc tgttaaaact acgtgtttat
     4621 gattcaaata agatgaatta tttttatcca tttcgtgtcg cattgggatt ggtgataaag
     4681 tatcaaaata tcccacaaca agattttcta acactaattc atttaattca gccgtcattt
     4741 gataatagga aaataaaaga catcattaac gactatcaca gtgttaatga taacaatgaa
     4801 attttttcgg aatttttgga tagaaatttt ccagagaata caagtgaatt gactgctgat
     4861 gaactttttt caaaaaaacc attaaataga aaagaatttg attcgctgtt cgtgaataga
     4921 aaatcttcag ctacgcaagg aatatatttt gaatttgtaa ataagttgtt ggcgtttaaa
     4981 tctaacaaaa atgttgaaaa tttagatgct ttgcttgaat tgaattctaa cgataaatta
     5041 acaaaggcat ttggatttgg aaaagctatt tttgctaaaa cgaattttat gaaatctaaa
     5101 aatatccaag attttttaga tgaaaacgta gataatgatt tgctgtcaga aaataatacg
     5161 ttgatttaca atcaatttgt actttctaaa aaagatgata tcgttcgtga gtatcgagat
     5221 atgacaaaac gaacattcaa tttatcggga ttattagact tcaatactgg actagtcaat
     5281 gctaccaatc aagatgttct ttcgataata tttagttcta tgagtttctc gggaactgaa
     5341 aactatgctg attatgaaga aaacttgagt tactcattct atcaagaatc tacaataact
     5401 gaggtattgg atttagatga atctgctatt ttgtcggaaa ttaaagcatt tcttggaatt
     5461 gaaaatactt cacaaatcga aagtgttgtt ttaacgcaaa aagaagataa atttagaaaa
     5521 tttatctcaa aaacatttcc tcgagaaaaa attattgaaa tcttaccgct attttcaccg
     5581 agagatgata aaaaaattaa atcagaagta tcagaatcgg caacggttcc aacaatttat
     5641 gaatatattg ttgctattgc atggttttat atttctaaag aagaattttt tattacaaag
     5701 agtttgaatt taaccttaga cggtgaaatg cgtccgttat cacatgcagc tggtggtgct
     5761 ggtgatattg tcattgatta tgaaaacttg acattaatgc ttgaagttac tttgatgaat
     5821 gcccaagctc aaaaacgtgg agaatgggag ccagtattac gacatgcaac aaatttgacg
     5881 gtagacaact ttgataagaa tgtcattact ttatttattg ctgatgaact ggacgataat
     5941 actgtaaata tttggcgagc agttgcaagt gtacctctac ggtcatcaaa taaagatgaa
     6001 attgcagatt tagtaaagat tttccctctg gagaatcgag aactacttca tatgctgaaa
     6061 aacaatctcg atgaacgaaa actattaaaa gcaattgatg aatcatacga agaacttgcg
     6121 ggcaattttg acttaagttg gcgagataaa atttttgttg aagctaatat gtaaaaatgt
     6181 agtagtttcg atttaaacgg gaatgttttt tagtcaatgg aaaatatcac ttaatggtgt
     6241 gaacttatgg taaaagctag ctcaattcgt tttatttagg gttaaaattc acaccattca
     6301 aatgatatta gttgaaatta gatgaagttt tgttatttgc aatcgcccaa aagatttgat
     6361 aataaaagct tttgaaagtt attcaattag gcgttgttca agccaggtct taaaggcgct
     6421 cgtcgttcac tacagttctc aacgttaata tcgttgctat ttcaacgttt acagcactct
     6481 ttggattatt tcaaagagtg tttttttgta tttttataga ggtatttaga taagtttgtg
     6541 gaggtttgtt gcgctttatt ttgctatcca ggagttcatt attttaaaag cttaaataat
     6601 aagc
//
LOCUS       DAXLPQ010000089         6453 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.092, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000089 DAXLPQ010000000
VERSION     DAXLPQ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.092"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..1234)
                     /locus_tag="ACF3UO_002576"
     CDS             complement(<1..1234)
                     /locus_tag="ACF3UO_002576"
                     /inference="COORDINATES: protein motif:HMM:NF021909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFD3658514.1"
                     /translation="MVGKNNKKLLELKSNPIIKKWRISRLKTGVASIVIFSGVLLSST
                     IFIPLHTVSAEETVTTTYYDQSKNVSDQLTNINISISNNKEKVIFPHNAESLTSNYAF
                     KVPDSVNPKDYFYIDLSENANFYGVTEANSVTMPNLLAPDNSIIATGKYDIDTNRIQY
                     EFTDYVAVHDNVSGKISLPIFIDPEVVTNTSYQTITASIGNSKKDLSLLVDYSKNVGP
                     QYNANGAGNIFNVDLNNHNFSHTIYVNSLKQTLGNKSIEIRNQRKEENGYNSEIIYDK
                     TNTQIKVYKVKSNGRLTDSFSIATNDSLEDVTNQCYIDFYDNKINISFPSNIDNETYV
                     VQYTSPYTDKKDIATRVVMYGYSPYQLGNTSWYWDNYVKLTDGNASGDGSVISPDPET
                     PVTPETPDPETPVTPETPD"
     gene            1563..2834
                     /locus_tag="ACF3UO_002577"
     CDS             1563..2834
                     /locus_tag="ACF3UO_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HFD3658515.1"
                     /translation="MNVFDATLKRLEYIFEEFDKVYFSFSGGKDSGIMVQLANLVAEK
                     LDRNFDLLILNIEANYTATVDFIKKIEQLPRVKNIYHFCLPFFEDNNTSFFQPQWKMW
                     DPSEKEKWIHSLPKNAITLENIDDGLKKYYSLSNGNPDRFLRYFQNWYKEQYPQSAVS
                     CGVGIRAQESLHRHSAVTKGENKYKNRCWINITLEGNILFYPLFDWKVDDIWAATFKC
                     GLEYNYIYEKMYKIGYKYRDMRICQPFGLQQRKALNQFAELEPETWDKLVKRVSGVNF
                     GNIYGKTSLLGLNTSQKPSFMTWQRYSIFLLETLGLYSPLLMNHYYRKICILFAYYKN
                     KYNMDIQDMPDESKRKDWIKDERLWNDWKGIAKALEKNDFVLSTRNYSLTKKDEAELY
                     EMFKEYKDFLGINQLKGKRYENIVQKIGGMK"
     gene            2831..3256
                     /locus_tag="ACF3UO_002578"
     CDS             2831..3256
                     /locus_tag="ACF3UO_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658516.1"
                     /translation="MSEIDIKVYIPPYNKQNFYSLMGKYFAERVYRRKLPYLINTPST
                     IWFLLMNKERIIGFSSIQISNEFIDIGDVFVEDENDDTRKYLLEKVLFFIDKKCERKC
                     VRISLKKDQYLNNLKHYCFKQYRETKNYLFFRREINEQD"
     gene            3243..3776
                     /locus_tag="ACF3UO_002579"
     CDS             3243..3776
                     /locus_tag="ACF3UO_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFD3658517.1"
                     /translation="MNKIDMPVLNVKMVPVEKIKSNNYNPNHVAEPEMELLELSILKD
                     GYTQPIVCYYDDKKDEYIIIDGFHRYLIGKSKLDLKELPLVVIDKPLEQRMSSTIRHN
                     RARGKHEIDKMSELVLLLVNEGWDDHKIGKELGMEKEEVLRLKQVTGLKSAFLNHEFS
                     ESWDEFVKKNYPKQKDE"
     gene            3910..4377
                     /locus_tag="ACF3UO_002580"
     CDS             3910..4377
                     /locus_tag="ACF3UO_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFD3658518.1"
                     /translation="MKFCETKKVLNQLVADLSVFSVRIHQVHWYMRGERFLFLHPKMD
                     DLMEQINDQLDVISERLITLDGSPYSTLEEFFTNSKLEEEKGSWNKTIDEQIDYLLEG
                     YNYLVSTYEEGIETAGKEGDDCTEDIFIGSKSELEKEIWMLKAELGNSPELDK"
     gene            5638..>6453
                     /locus_tag="ACF3UO_002581"
     CDS             5638..>6453
                     /locus_tag="ACF3UO_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658519.1"
                     /translation="MFTSCKEKRLKFAIRKKKGGGAASFIIGCLIFGNIFLNGAIANA
                     SSIENSYAISGFGNQTKGGYFLYNKGIKTESVIDNQVAFCFDKNVIAKLNDRGFSNPG
                     YQLYNEKDEQLLKVYSNEKINKVRNIMAYAWDNFITKYPYLNTYTAASNDDRASLARG
                     ISHAIWVTLGQTTEKKSRSDLGGVNTNAYKFYKEALNYKPLAKDINNYDISLLIPTDD
                     NNILQVNASQSLITVKKIDPDKPVNPDPETPVTPETPDPETPVTPETPDPETPV"
BASE COUNT         2407 a          780 c         1049 g         2217 t
ORIGIN      
        1 gatctggagt ctctggtgtt actggagttt ctggatctgg agtctctggc gttactggag
       61 tttctggatc aggtgatatc acactaccgt caccacttgc atttccatct gttagtttta
      121 cataattatc ccagtaccag ctagtattgc ctaattgata aggagagtaa ccatacataa
      181 ctactctagt agcaatatct tttttatctg tataaggaga agtatattga acgacataag
      241 tttcgttatc aatattgctc ggaaaactaa tattaatttt attatcataa aaatcaatat
      301 agcattgatt agtcacgtct tctagtgaat catttgtagc aatagaaaaa ctgtcggtta
      361 gtcttccgtt tgattttact ttataaactt ttatttgagt atttgtctta tcgtagataa
      421 tttcagaatt atatccattt tcttcttttc tttgatttct aatttcaata cttttatttc
      481 ctaaagtttg ttttaaagaa ttgacataga tagtatgaga aaaattatgg ttattcaagt
      541 ctacattaaa tatgttacca gcaccattag cattatattg aggtcctaca tttttagaat
      601 aatccactaa cagactcaaa tcttttttac tattgcctat actcgcagta atagtttgat
      661 aagaagtatt agttactact tctggatcaa taaagatcgg taaagaaatt tttccactaa
      721 cattatcatg cactgctaca taatccgtaa attcgtattg aatacgatta gtatcaatat
      781 cgtattttcc agttgctata attgaattat ctggagctaa gagattaggc attgtgacag
      841 agttagcttc tgtaactcca taaaaattag cattttcact caagtcaata taaaaataat
      901 cttttggatt aactgagtca gggactttga atgcataatt tgaagttagc gattctgcat
      961 tatgtggaaa tatgactttc tctttattat tagatattga aatattaata tttgttaatt
     1021 gatcactaac atttttagat tggtcataat aagtagtagt tactgtttct tctgctgaaa
     1081 cagtatgtaa aggtataaaa atagtagaac ttaataatac cccgctaaat atgacaattg
     1141 atgcaactcc tgttttcagt cgactaattc tccacttttt gataattgga ttgcttttta
     1201 attctaataa ctttttattg ttttttccaa ccataaaatt atcctttcta cataatttat
     1261 tcgaacgata aaaatgatcg ttcattttca ttataataat atttaatgga aaaacaagtt
     1321 aaaaatattg tttgaataat aattccaatt atttctataa tatttgttaa ctgtaagata
     1381 ctactagact aaaatccatt tttgtttttt taagtaagta tagtatataa attaaaggtg
     1441 ttccttacat tattctatat gatttgaata ctataagaaa caacaattga taaaattatt
     1501 gacaaagttt ttaaaggtat taccattgat attgaacgct tattttttta gggggatgag
     1561 aaatgaatgt ctttgatgct actttaaaga gattagaata catatttgaa gaatttgaca
     1621 aggtgtattt ttcatttagt ggtggtaagg atagtgggat aatggttcag ttagctaatc
     1681 tagttgcaga aaaattagat agaaattttg atctattaat attaaatatt gaagcaaatt
     1741 acacagcaac tgttgatttt ataaaaaaaa ttgaacagtt acctagagta aaaaatattt
     1801 atcatttttg cttacctttt tttgaggata acaacactag tttttttcaa cctcaatgga
     1861 aaatgtggga tccaagcgaa aaagaaaaat ggattcattc tcttcctaaa aatgccataa
     1921 ctttggaaaa tattgatgac ggtttaaaga aatattattc attatcaaat ggtaatcccg
     1981 acagatttct tcgttatttt caaaattggt ataaagaaca atatccccaa agtgctgtat
     2041 catgtggtgt aggtataaga gcacaagaaa gtttacatag acatagtgct gttacaaaag
     2101 gtgaaaataa atataagaat cgatgttgga taaatataac tttagaagga aatattttgt
     2161 tttatccttt atttgattgg aaagttgatg acatttgggc tgcaactttt aaatgtggac
     2221 tagaatataa ttatatctat gagaaaatgt ataagattgg atataagtac cgggacatga
     2281 gaatatgtca gcctttcgga ttacaacaaa gaaaagcgtt aaatcaattt gctgaacttg
     2341 aacctgaaac atgggataaa ttagtaaaaa gagtaagtgg agttaatttt ggaaatatat
     2401 atggtaaaac tagtctttta ggattaaata cttctcaaaa accttcattt atgacttggc
     2461 aaagatattc tattttttta ctagaaacat taggattata ttctcctctt ttaatgaatc
     2521 attattacag aaagatatgt attctttttg cttattacaa gaataaatat aatatggata
     2581 tccaagatat gccagatgaa tcaaaaagaa aagattggat aaaagatgaa agactttgga
     2641 atgactggaa agggatagct aaagctttag aaaaaaatga ctttgtttta tctactagaa
     2701 attatagttt aacgaaaaaa gatgaagctg aactatatga gatgtttaaa gaatataaag
     2761 actttttggg aataaatcaa ttaaaaggaa agaggtacga aaatattgta caaaaaatag
     2821 gaggaatgaa atgagcgaaa tagatattaa agtttatata cccccataca ataaacaaaa
     2881 tttttacagt ttaatgggga aatattttgc tgaaagagta tatagaagaa aattacctta
     2941 tttaataaat acacctagta ctatttggtt tttgttaatg aacaaggaaa ggataattgg
     3001 attttcttcc atccaaattt ccaatgagtt tattgatatt ggagatgttt ttgttgaaga
     3061 tgaaaatgac gatactcgaa agtatctatt ggagaaggtt ttatttttca tagacaagaa
     3121 atgtgaaaga aagtgtgtac gaatttcttt aaaaaaagat cagtacttaa ataatctgaa
     3181 acattattgt tttaaacaat atagagagac aaagaattat ttatttttta ggagagaaat
     3241 caatgaacaa gattgatatg cctgttttaa atgtaaaaat ggttccagta gagaaaataa
     3301 aaagtaataa ttataaccca aatcatgtcg ctgaacctga aatggagctt ttagaattat
     3361 cgattttaaa agacggatat acacaaccaa ttgtttgcta ttatgatgat aaaaaagacg
     3421 aatatattat tattgatggg ttccataggt atttaattgg aaaaagcaaa cttgatttaa
     3481 aagaacttcc tttagttgta attgataagc cattggagca aagaatgtca agtacaatta
     3541 gacacaatag agctagaggg aaacatgaaa tagataaaat gtccgaatta gttctactgc
     3601 ttgtcaatga aggatgggac gatcataaaa tagggaaaga actaggaatg gaaaaagaag
     3661 aagttcttag attaaaacaa gtaacagggt tgaaaagtgc ctttttgaac catgaattta
     3721 gtgaatcatg ggatgaattt gtaaaaaaaa attatcctaa acaaaaggat gaataagtgg
     3781 taaagatttt tataaacacg attttaatat aaacgttcat tttattgttg acaagatata
     3841 tttgttatat taaattatgt gtaaatcaga attatttctt ttaaaaaaat ttaaattagg
     3901 agtgatatta tgaaattttg tgaaacaaaa aaagtattaa atcaattggt agccgattta
     3961 agcgtatttt cagtaagaat acatcaagtt cattggtata tgcgtggaga aaggtttcta
     4021 tttctacatc ctaaaatgga tgatctcatg gagcaaatta atgatcagtt agatgtaatt
     4081 tcagaacgac tgattacact tgatggatct ccgtattcaa ctctagaaga gttttttaca
     4141 aattccaaat tagaagaaga aaaaggctct tggaataaaa ctattgatga acaaattgat
     4201 tatttattgg aaggttataa ttatcttgtt tcgacatatg aagaggggat tgaaactgca
     4261 ggaaaggaag gcgatgactg tacagaggat atttttattg gttctaaatc agagctagaa
     4321 aaagagattt ggatgttaaa agcagagtta ggtaactcac ctgagttaga taaatagata
     4381 cagaacttca agtgaatggt tatgatattt ccttgtgaat agggagtgtt tttcagtgtt
     4441 tctatgaata ctataagtga gattgataaa aaaacaaaaa catctaagga gagatttatt
     4501 tctaccttag atgttttttc actaagtgat ctgtttcagt cgataaatat aagtgcaggt
     4561 agattttaac aactaattat atcaaagaaa taagtatata gtactgtaaa aatatatatt
     4621 ataaattatc ttaacaaaga gttgatggga acatacacaa tctaatagta tgtcagatat
     4681 gtatataaaa ttagaaaact gagcgaaaga aacattggaa gaatattttt taactatgct
     4741 cttttatatc tatatataat atgaaaatat tatttggaga aatagattct gatggactga
     4801 gaaaaagtat aaaaagctat aaaaaatata aaaagaaaaa atatgctgat acacgttgta
     4861 tctattttca tcccgaaatt cccataaagt gacagcatac tttattcatt taatcatggt
     4921 ataagaagca gctatttcta ctttttgaga acttaatttt aagcttgcgc tatatttttc
     4981 gctacaacat tataaaaaat aagttaatat gcttattttt tgctttgata attctaatat
     5041 acattttcag gggcaactcc ttcccctgag ttgcccttag agagtgatat tgggatatcc
     5101 ctgaacctat tatagaaata ccaacatctt agctcaacaa atttgcttta tattgcaaaa
     5161 aatgatctaa attatctctt tttttatcta tagattatta aatgtatgga agaattaaaa
     5221 taagataata aattttggaa aagaaatcat atttcaagtc ctaagattaa caacaaagct
     5281 tattatatat aaataaaaac tgttcaagaa tattttctta taaatagttt tatcttattt
     5341 acaaatataa tagaactcag tggacttatt cccagatagt ttttagataa cactgatagt
     5401 gaaatgttga agcaaaatta gcattgatta cctgtctaat tttaatgttt tatagtgagt
     5461 ctacctgaaa ataaaagtgc ctcatcataa ttgtttctta aaaaataaac gatcattttt
     5521 ttattgaaat ttccggaaaa ttaatttata cttttatcga aaaacattct aatttgaatg
     5581 ctttttcttt ttgtctataa aacatgaacg ttcattttgc ggtaaggaga gatgggaatg
     5641 tttactagtt gtaaagaaaa aagattgaaa tttgcaatta gaaagaagaa aggtggtggt
     5701 gctgcgtcct ttataattgg ctgtttaatt tttggaaaca tatttctcaa tggcgctatt
     5761 gctaatgcgt ctagtataga aaatagttat gcaataagtg gttttggtaa tcagacaaaa
     5821 ggtgggtatt tcttatataa taagggtatt aaaactgaaa gtgttattga taaccaagta
     5881 gctttttgtt ttgacaaaaa cgttatagct aaactgaatg atcgtgggtt ttcaaaccct
     5941 ggttatcaat tatacaatga aaaagacgaa caactcttga aagtatatag taatgaaaaa
     6001 attaataaag taagaaatat catggcttac gcttgggata attttattac taaatatccc
     6061 tatttaaata cttatacagc cgcttctaat gatgatcgtg cttctcttgc cagaggaatt
     6121 agtcatgcta tttgggtaac cttgggacaa acaacagaga aaaaatcaag aagtgattta
     6181 ggtggcgtaa atactaatgc ttataaattt tataaagaag ctctaaatta caagccactt
     6241 gcaaaagata ttaacaatta tgatattagt ttacttattc caactgacga caataatatt
     6301 ttgcaggtaa atgcttctca atcattaata acggttaaaa aaatcgatcc agataaacca
     6361 gtaaatccag atccagaaac tccggtaacg ccagagactc cagatccaga aactccggta
     6421 acacctgaga ctccagatcc agaaactccg gta
//
LOCUS       DAXLPQ010000090         6434 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.093, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000090 DAXLPQ010000000
VERSION     DAXLPQ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.093"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(133..717)
                     /locus_tag="ACF3UO_002582"
     CDS             complement(133..717)
                     /locus_tag="ACF3UO_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658520.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(928..1131)
                     /locus_tag="ACF3UO_002583"
     CDS             complement(928..1131)
                     /locus_tag="ACF3UO_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658521.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(1141..1563)
                     /locus_tag="ACF3UO_002584"
     CDS             complement(1141..1563)
                     /locus_tag="ACF3UO_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658522.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1801..2415
                     /locus_tag="ACF3UO_002585"
     CDS             1801..2415
                     /locus_tag="ACF3UO_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658523.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2580..3404)
                     /locus_tag="ACF3UO_002586"
     CDS             complement(2580..3404)
                     /locus_tag="ACF3UO_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658524.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3428..3583)
                     /locus_tag="ACF3UO_002587"
     CDS             complement(3428..3583)
                     /locus_tag="ACF3UO_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658525.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
     gene            complement(4042..4299)
                     /locus_tag="ACF3UO_002588"
     CDS             complement(4042..4299)
                     /locus_tag="ACF3UO_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3658526.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(4292..4561)
                     /locus_tag="ACF3UO_002589"
     CDS             complement(4292..4561)
                     /locus_tag="ACF3UO_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3658527.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(4692..4871)
                     /locus_tag="ACF3UO_002590"
     CDS             complement(4692..4871)
                     /locus_tag="ACF3UO_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658528.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(4887..5087)
                     /locus_tag="ACF3UO_002591"
     CDS             complement(4887..5087)
                     /locus_tag="ACF3UO_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658529.1"
                     /translation="MNKIIPLLFVLFVGEILMRHGAALHLNFVVFLGILVFCLIFWRF
                     VLTLVSLIFKLIAAIFLIGLFR"
     gene            complement(5252..5959)
                     /locus_tag="ACF3UO_002592"
     CDS             complement(5252..5959)
                     /locus_tag="ACF3UO_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658530.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(5952..6389)
                     /locus_tag="ACF3UO_002593"
     CDS             complement(5952..6389)
                     /locus_tag="ACF3UO_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658531.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
BASE COUNT         2001 a         1192 c          908 g         2333 t
ORIGIN      
        1 taatattaac aaatgaataa aatccttaca acatttgaga ataagttatc agtagacact
       61 tacaaaaaat tctcatacta ttgtcacttt tctagataaa tggcaaaaat tttcagcatt
      121 aaatgacaaa aactaatgag aatttgtctt tccatttttc tcctccattt ttgccaaata
      181 acgataaatg gtggttcttg agacgttcca ccgttccgca atagtcttaa taggtgtacc
      241 gctatccact aaagtcttca gtaattccaa atcttgttca gacaattttt caggacgacc
      301 accaaaccgt cctcttgcac gagcagctgc tcgtcctgct gcggatcgtt ccaggatcaa
      361 attacgctca aattctgcaa atgccgcaaa caaatgaaac atgagctgtc ctgtagaact
      421 tgatttgtcc atcgtaatat tttcttgaat actatgaaaa ctcacaccac gctcattcag
      481 tcgattgacg attgaaatca aatcttccat atttctacct aaacgatcta agcgccaaac
      541 gacaagtgta tcgccagagc gaacaaaatc aatggccatt tctaatcctg gtcgattact
      601 ttttgcccca ctcatatgat cagtaaaaat tttttcacaa ccaaatttat ttaggctgtc
      661 ttcttgtaaa tccaaatttt gtaaaccagt agatacccgg gcgtatccta ttttcaaaaa
      721 aatcactcct tcattaattt tattgtaaca taactttatc catatagttt aactgaacat
      781 agatattgtt atgggtttat gaacatgaaa tgaattgttt ttttgaaaaa taaagcaaaa
      841 aaagaaagtg tccagaaatg ggtgatttta tgaacacttt caattagaaa aaaagaatgt
      901 cgactagaca ctcttttttt aaaatcatta tttttctttt tgatatgttt tttggtctct
      961 tttttttctt ttttcttcag aatcttctag attagaaatt gatttttgaa ttttttgtgt
     1021 ctcctgtaaa gttcgctgaa cttgtaaagc tgattcttct ttcggtaaat taattttact
     1081 tagaatatcg ctatcttgat aaaaatttgg tgtgttcaca aattctggca taaaaaatcc
     1141 ctactttcta gttaaggttc ctgaataagt cgcaatccaa ttgtttccag ctgatttata
     1201 actttgtaaa tacaattttc catagtacca ataaccattt cttttttctt tccaattccg
     1261 tgattgagga ggtctagaag gccaaccaac tttatcaaaa atcatcgttc ctgtcactcg
     1321 tatcgtttta gaagctgcta gagcaagtaa tggagaaact attaaataat tttcagtaac
     1381 agttaagtcg ttagttgggt taccaatggc tattccgtcc ctatctaaag gagttaattc
     1441 ttggttatta tctactacag tagttggttc atttgtacta tcagcaaatg taggaattgt
     1501 agttccagtt acactaattc caatagttaa aatacctaaa gataaaataa acttattttt
     1561 cattgtctat cacctcgaaa tcaaaactaa gaaaacgttt tcttaataaa tcttaacaga
     1621 taaatcaagt tatatactag aaaattcata aaatatattt ttaatgtcat aatcgtttaa
     1681 attttcttga ttgacattta tttacaaaaa atattgccat ttaaaaagaa aagtgacata
     1741 tggcttcctc gtgtatgatt agggtgtatt ttaaatagtt gcagaaagta ggtaaaagtt
     1801 ttgagagttg catacatacg tgtctcatcg atcgatcaaa atgaacaacg ccagattgaa
     1861 gaaatgaaaa aattcggtgc agagagaatt ttcatcgaga aacaatctgg cgcaacgatt
     1921 actcatcgac ctgttttcca agaagcatta gattacgtcc gagatcaaga tatttttatt
     1981 gtggaagcta ttgatcgact tggaagaaat tatgacgaga tcatcgcttc agtcaattac
     2041 ttgaagaaga aaaatgtgaa gctgatcatt actagtttac cgatcatggc tgaagcaatt
     2101 ggcaatcctc tcctggataa attcattaag gatctgatca tccaaatttt ggccatgatc
     2161 gctgaacaag aacggactga atcgaaacgt cgccaggcac aaggaattaa gatcgcaaaa
     2221 gcaaacggcg tctacaaagg gcggcccaaa ttatacagtg cagacgcaaa agatccccaa
     2281 cgtcgccttg tttacaaaag catcgttgaa gatcttaaaa atggtgttgc gattgctaag
     2341 attgctaaag actacaatgt tacgagacaa accgtgtata gaataaaaaa agacagcatg
     2401 gtcaatgaca aatagttgat catgctgctt ttattatctt ctcatcttta atttcctaca
     2461 tataattact atctataaaa ttaagtctta ctcagaacag ataaagcata aaattccaac
     2521 aaaccatttt ttacttaact aaataaagag tctgttaata taatcttcac ttatttacgt
     2581 taatccccta ctgtatttgt tggttcctta tctatatttt ctacaaaatc cttattatct
     2641 tgtgatttag cttcgtataa ttctttgtat gtcgacacat tggttatact aattcctata
     2701 gctagttctt gagactctac ttttctctct agctcctttg acaaagtgat ttgagattta
     2761 tttggttccg ttggagtcaa ttctatagat tcttcataaa aatctctata cataaagcta
     2821 tcattaattt tataaaaaaa attaaatgtt tttagcactg ccatataaca ttcaaaacat
     2881 tcttctatag ttggtttact tccttgagga gaatgaacca atttattacg tttttctatg
     2941 aaatttttaa tttcctttct tatttctttc ggaaactcaa tattaaagta ccctttaaac
     3001 atgctcccta ataatttgtc tacaggggga gattgtaaat tctcaaatat tagagttaaa
     3061 tcaggtttct cttgttgata aaattccttt acccctattt cacaggctgt aattatcgaa
     3121 ataaacctat ctctagtatt tgatatattt ttacttcttt taaggagtat aagagaaaag
     3181 gggatacttt cgtgtccatg catgtaatta actaattgtt gagcttcaga agttatatct
     3241 ctaattatat agttaacgga attaggaagt gtctttaact ctaatgaaat ttctatccaa
     3301 ttactatctt ctaatctgta tatgctcgaa gtataatttg attcgtcagc aagcatcgct
     3361 acatcccaaa cactgatcat aaaatctttt aaacgttcaa tcatttcagc aatattgcta
     3421 aaatcagcta atttttcttt agaataaaaa aaacatttat atcagaatca ataaattcta
     3481 ttttttttat tactatatcg tcatcattat cttgaccatt tatgtttatt gttccctgag
     3541 tggggagtac ttctttcaaa ttcaagttaa atttatattc cattacttct cctccaatat
     3601 ataaaaatta cttaactgta tccaaattta atatgtaaat aaatcattaa tttttagcta
     3661 aattctatga gaagtttatt tttgttgttt ttgctaatta actaaaacta gtacaaaaaa
     3721 tttaaaatag attattaaac ctattgctta ttctattcag tcatatatat aagcgtcatc
     3781 ctttagtaac taacatccca cactacaata gtattataac atatctattc aacttcaaat
     3841 tgttgaaatt taagccattt atatttactt ttcctcaact ttagaaatga ttttactaac
     3901 cttatatccg taatacgcgt aacaaacaca ttcattaata acaatcaaca ctaagctata
     3961 ttagcttttt aaatgactag ggtaaataaa ataaggatca aaaactttta agtttctgac
     4021 cctttcctta cttccgattg gttaatagtg atcttttgca gaataaataa atatcgtttc
     4081 attttcaact ctatatatca gtctatgttc atctgtaatt cttctggacc attttccaga
     4141 taaatcatgc tttaatggct caggttttcc taatccagca aagggggaac gatcgatatc
     4201 ttttattaac ttgttaatct tttttatatt gcttttgttt ccttgctcat gccaataaag
     4261 ataatcatcc caagcatcat cagaccaagc cttaatcatc agattcaacc tcgattaagt
     4321 catgtgtttt aaatgcacct ttggagaatt gttcatctcc tcgacgaatt ttttccatga
     4381 cgtaattatt agaaagtgtt ctcaacgttt cttgcataga atcataatct ctttttgata
     4441 atacaacaac tgtatcttct acatctttac ttgttacaat aagtgtttca gcatcctcat
     4501 taacttgttt catataacta cgtaaatttt ggcggaaatt tgaataagct actgcttcca
     4561 ttcctttcac cccttattta tttctataaa acaattgtac attatattgt acaattaagc
     4621 aaatgattaa tattctaact tcttataatt aaaagtgcta tcacttttag tttttaggat
     4681 aaaaagtgac gtcacttttt gagtgctggt acctcaaatc ctgctttttc ttgggcaatc
     4741 aataaatcta acgcaataca cataatcctg gattcacttt tgccgtactt ctgctttagt
     4801 tgctgcaatt ctttttgtct cttttcatcc aacgtcacgg gtaaccgttt atttcctatt
     4861 gcaattggca ttagtactct ctcctttcat cgaaataacc ctattaaaaa tatggctgca
     4921 atcaacttga atattagact cacaagggtt aacacaaagc gccaaaagat caaacaaaat
     4981 accagtattc ctaagaatac tacgaagttt aaatgtagag ctgcaccatg acgcataagt
     5041 atctcgccaa caaacagtac gaacaataga ggaatgattt tattcatatg gatctccttc
     5101 tttctcttag gttatcgggc tttgcccgct tatttcgcac cacctaagcg gcgggggcgg
     5161 ttggatcgat tggtgcgaaa taagaaccat tcccttaatt tcaaggtttt ttgttcttat
     5221 ttcacacatc ctcacttttc ggtataaatg gttattgacc ttttttcctt tcaaatcgtt
     5281 gatatggcat tcgtttacgg tcaagttcat tttggatttc ttctgtatcg tcgtaagtgt
     5341 aggtgtctaa aaaatcagtt aaagtcgtgt accagtcgtc gcctgggtta tctacttctt
     5401 ctacatattc cctcaaaaat gcttcgggta cagtgagttc ataatccatt cccattaaca
     5461 cgatagattc cgtcccacac gtcaaaaatc tagtaaatac aaggtaataa tcgtctaccg
     5521 tcgcatcttt gctgtttagc tcttccattt cttcttccat taattccatg ctctcaaaaa
     5581 ttgaataata ttctgattct gagtaatagt gtttcctgca aatcgtgtag ctgacaaagt
     5641 tttcgaccag ctcactcctt tctaggtaaa cattcatgat atatttttct gtttctagtc
     5701 gtagaagctc cgctcctttt tttaatgtgt caggacgacg tttatacacg tctaaacgat
     5761 tatggctgac tgtaaccttc gtttgactcg tttcactttc catatacaac tgttcttcca
     5821 ctctttgaat aaagtacttc atttcttcca tacaactaaa gtctttttga atccgtctga
     5881 ttacttcatt caagtgttct ttgtttgtta aaaattgcga aacatcttct gttgttagct
     5941 gataaaccac cttattcatt atctttctcc tccgattcaa tcgtataaaa tgcaccattt
     6001 ttttcgatat tttcaaaagt atctagccag tcgctagcca ttgctttagc tttcttaatc
     6061 tgtgcgaatt ttgcataagt cagttctaag gcttgatatt cggaaggttt gatagtgctt
     6121 ggtttgacac ctacttccaa gcatagtaag gcttggaaaa accattttcc attttgtttt
     6181 ttcagttctt ccagtgttcg atagtacgtc gcaatgagat tcatttcgac acctgattca
     6241 atcatttctt ccactgcgac tgacaatttt tccttgtaat gttttttggg tacacgtgtt
     6301 tcatggtata ggaacgtcat atcctccatt ttttgtgcca ttttatccaa aggtaatttg
     6361 acaaattcgt catagtaatt ttgagccata ttttttctcc tttttagttc tctaatttgg
     6421 ttaaccaata ttcg
//
LOCUS       DAXLPQ010000091         6188 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.094, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000091 DAXLPQ010000000
VERSION     DAXLPQ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.094"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            725..811
                     /locus_tag="ACF3UO_002594"
     CDS             725..811
                     /locus_tag="ACF3UO_002594"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFD3658532.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACF3UO_002595"
     CDS             complement(932..1621)
                     /locus_tag="ACF3UO_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658533.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="ACF3UO_002596"
     CDS             complement(1628..1906)
                     /locus_tag="ACF3UO_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658534.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="ACF3UO_002597"
     CDS             complement(1866..2780)
                     /locus_tag="ACF3UO_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFD3658535.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACF3UO_002598"
     CDS             complement(2762..3142)
                     /locus_tag="ACF3UO_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFD3658536.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACF3UO_002599"
     CDS             complement(3592..3879)
                     /locus_tag="ACF3UO_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3658537.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACF3UO_002600"
     CDS             complement(3899..4123)
                     /locus_tag="ACF3UO_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFD3658538.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4593..4763)
                     /locus_tag="ACF3UO_002601"
     CDS             complement(4593..4763)
                     /locus_tag="ACF3UO_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658539.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4778..5311)
                     /locus_tag="ACF3UO_002602"
     CDS             complement(4778..5311)
                     /locus_tag="ACF3UO_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3658540.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5332..>6188)
                     /locus_tag="ACF3UO_002603"
     CDS             complement(5332..>6188)
                     /locus_tag="ACF3UO_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFD3658541.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1641 a         1153 c         1041 g         2353 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatttattat ataacaatga ttaacgtcat aaaaagtagt tttgaattca
     4261 taatcgttta aataaaatta taagatcagt tatttaaaca gctagtagac ataatgtaca
     4321 tactaccaag taacgcctgt accaagggat ccaggcgctg attttgtgaa tttttattgg
     4381 tctaggttaa aagctctttt taaggcttgg ttttctgcgg ttgtttcttt ctaattcttt
     4441 gtgaatattg atcggtcatt ttttaaatac ttgttatttt tgtttgtgtt tgttatgctt
     4501 tttacatatc tcatattcat ttattattct tttctaaggt taataatagg ataatctctt
     4561 tcagaaagac tgctcgtacg agcagtcttt tcttatttat caagtttttc tacaaatact
     4621 tcctcatttt gactgttgta gtaattagga ttgagtttta gttccccttt tttatttcct
     4681 ttgttggcca ctgataataa cattgggcta aagcttaata ttcctagtag gatagaaccg
     4741 aatagcaagt gtttttttgt cataagtatt tccttcttca tttccatagc tgccaccatt
     4801 ttttccaatt ctttgtttgt tcgtccattg tttctgttgc ttcagaaaga gtcgttgaac
     4861 tattctctga agactcttcc gtataagtca actgcagttg ctcctgaagt ttttcgattt
     4921 gttggttggc ttgcagggtg agttgttgtt gctggtcgag tagtttttgt atatgagaat
     4981 tattttgctc tttgagggca agttgttctc gtaaaaattc attttcttca cgcaactgat
     5041 ctagcaactt gtttgcaacc acgtttttgt ttggtatata agcattttta tcgttgtttt
     5101 gttcatgttt atgcaactta tctagcaacc tttgattgtc taagttgcga gcaagttgca
     5161 atactccaga acgcaataca accttataac cacgctcatt tttagctatc atggaagaat
     5221 ctaatttttg gatatgtttc gatattgctt gcctactcat cttaaaaaga tctgacaatt
     5281 cctttattgt aaaggtttct tgtggttgca tactggttgc ctcctaggtt gctactggaa
     5341 taaattatct aaatcagata ataaactttt tttctctttt tccgaaagtg cggactctgt
     5401 ttgtttttca agagcttttt tctctttttc tagttgtttg atttgttgga ggagttcaag
     5461 ttctcgtttc ttctgtttga ttttttcgtt aattgttgta gcgggttctt cgtattcttt
     5521 ttgtttatca gctaaagcca atgctttatt ttggtcttct ttggttggtg catgtttgtt
     5581 aaagtcgtct gcttttttga tctcaggttt gaacgtaaat tgatagccaa taacaggttt
     5641 tccccgtcct tttccgtatt tctttttgat tgttagtcct ttgaagattg cagttagttc
     5701 ttgacgtata ggttttataa ctcgtttatc tatatcaggt tgcttataac ttttaggaat
     5761 atctaataat tcaagaaagt cttctttgga gaaatatgcg aaacctttgg ttctgtattg
     5821 ctttaacaga cgaaacatag tctttgcata gccactttgt agctcgttga attgttgtaa
     5881 agaatagcgt acccactcgt ctaaattatt taacaaaggc agtgcttttt cgtaaattcg
     5941 tatatctacg taaggatttt ctacgtcccc gttgatttta aattctgtaa acattacaaa
     6001 catatcgtaa gaaagcccag actcacttct acgaccaaag cgtaaagata agattttttc
     6061 ataagttgct tttaaatctt ctacaaatcg tacatttgca gttgctttgt agttacttaa
     6121 atcttttagt tggtcaaacg taaaacgaac tgtcttatcc cctttttcac gcattctaga
     6181 cacgatgg
//
LOCUS       DAXLPQ010000092         6156 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.095, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000092 DAXLPQ010000000
VERSION     DAXLPQ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.095"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            790..2340
                     /locus_tag="ACF3UO_002604"
     CDS             790..2340
                     /locus_tag="ACF3UO_002604"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3658542.1"
                     /translation="MSDKNTYARRSQRHKQEPDSCENTNQLNEAVKPQTGNENKQPKI
                     PKKKSNYSKYIFALFTALILVIVVTGGYIVYTLKQQEAEAQAKYETAAKNLMASIQEE
                     QDQSGISTKIDTINDGENKCLVYRPVDENTVPFKNANQLLDELAQKQQKKHREKEVLT
                     VARIKATAISSKVNQYRIEADSFIWDRSKENFKKPDSISEKDIYIFKKTGKEITNKDL
                     FPDEGSLLGIQQVIQQSILDQAKEPEKIIDAVLTMDRISYDSKMTYTPDELTIVLPKN
                     STGTSKVTLKYKDIAPFIDTDLVSQESIKDTLPALDENKKYVALTFDDGPNNSSTLDL
                     LNILKTDNVKATFFMLGQMVDQNPDVAKQVHDEGHEVACHSYSHPQLNTLSTDELQSE
                     INKANKAIFKATGVLPRNIRPPYGAIDKKSAETIGMPIIQWDIDSQDWKSKNPRAINN
                     VVKQNVYNGAIILIHDIHPESVKAIPNMISMLKNKGYEFVTIDQLLSGKQKPLHQYFG
                     MNDERLVD"
     gene            2625..2844
                     /locus_tag="ACF3UO_002605"
                     /pseudo
     CDS             2625..2844
                     /locus_tag="ACF3UO_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3856..>6156
                     /locus_tag="ACF3UO_002606"
     CDS             3856..>6156
                     /locus_tag="ACF3UO_002606"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658543.1"
                     /translation="MFYQRSEKKFKYAIKKKKGGGGAASFIIGAMFLGIGLISCPTVS
                     FASETTEINQSTEIQSTLNNSILKESNSEEKQNIDVSEDSAINKDLELASKATISESE
                     NSFGETTNNQENTNLSEDSIEVQPESIIQKEVLTDNDAIQQLEVHPHEDSDDAALVEN
                     QMTRVTEESIKSNTSQVDKDTTVLSNTTRDLVNLEDTAIENVTPQKTIKKDSISLLEE
                     NNSSSASRTLRRSVRSLDVQTGENFLEDWALPDNSNISGSLITQTGITYVGVKTDDPT
                     QLHLKMAYRAAATPASIDWIYLRVDPELTKYIEEINIKNTVNIGAQVGYQRYFEKVDT
                     NTLSNVNTFGTPTGVSDAYAQVDQKTGGIYRVLLDKFFIRIPGTNPKSRGALSGNWGV
                     FPSVPLEAERYEANIYIKLSKDVAELQQELGRDKFGVQLRLQGQSSSGVATIAKESLN
                     KNTIVDLSQEEPDENNSNWLNSPSVHTITTTYEGKQMGSDGQFSSILEGTDKSLIRVQ
                     NTIMNNLLYGTALDLGRPVSFNIEIDPQILNLVSDDDYITIWQVYRENSINHHDGGSN
                     APVMLKKNMFVDNKIKIEVNKDKAGQYGNGVYYVNAVESFMNTLSSSPFVGANFIDIP
                     VMPKSLIEDEDQLISAEIKTWFTDKKNDQERIVRNSLASSYINLFPTTINFYDYSTKD
                     TEQLLKLRESTYLVSTFGQEINGMDMGETYEISNYEFVTADPESLIITQKDGNIINLY
                     YKKLSSDAEFYEPEVEKEEVNYGETID"
BASE COUNT         2310 a          879 c         1043 g         1924 t
ORIGIN      
        1 ttttttgttg atttaccaac atgtttagac attttcctct aggaaaaaat taactagcac
       61 cacgggtttt tgtactatta attgtgattt ttaaatgatt gaaaaataga gaggaggaag
      121 caatacgtag aaaaaatatt ttaaattggt gtaagtacaa atatgttatt tacagtattt
      181 tagtttctcg tattaagtgt tactactatg gtgaattctt tagagaatta ataaatagtc
      241 ttctttgata gattgttaaa gggaacttaa caaagtaata agatgcataa tcaaatgcac
      301 aaaaaacaaa aaaagaagtt tcttcgaata gaaattctga aataacatcc tttcgcctaa
      361 tagtgaataa tttaaataaa gagaaactgg ctacactatc aaagcaagtg attctgttta
      421 gctaattact aataattaaa gtattaaaat agtatgttta atcaaataga acaagattgg
      481 ataatagttt atatttttaa tcctagacca ttattggtat ttcaaagact acaaccatac
      541 taattaatct atcgaatggt acaatttcaa aaactaaaat caaaactagt gattctaatg
      601 ttatcaaaac tgagttgaaa attaagtagc cacaatatct aaagtggtga ggaattagcg
      661 ataattacta cgccgaaagt aaaagaataa tagaaaaaac tttccttaaa aattatctat
      721 gaattcgttt tcattataat tgcgctgttt tattttactt tatgatgata aatggaggga
      781 taaagtcata tgtctgacaa aaatacctat gcacgtcgta gccaacgtca caaacaagaa
      841 cctgatagct gtgaaaatac aaatcaattg aatgaagctg taaagcccca aaccggaaac
      901 gaaaacaaac aaccaaaaat accgaagaaa aaatctaatt atagcaagta tatattcgca
      961 ttgtttaccg cacttattct agtaattgtc gttactggcg gctatattgt ttatacatta
     1021 aaacagcaag aagcagaagc tcaagccaaa tatgaaactg ctgcaaaaaa tctcatggct
     1081 tcaatccaag aagagcaaga ccaaagtgga atttcaacga aaatagatac tataaatgac
     1141 ggagaaaata agtgccttgt ttaccgtcca gttgatgaaa atactgttcc tttcaaaaat
     1201 gcaaaccagc tcttagacga gcttgctcaa aagcaacaaa aaaagcatcg tgaaaaagaa
     1261 gtgctcacag ttgccagaat aaaagcaaca gcaatatctt ctaaagttaa tcaatataga
     1321 attgaagcag atagttttat ctgggatcgc agtaaggaaa atttcaaaaa gccagatagt
     1381 atttctgaga aagatatcta tattttcaaa aaaactggca aagaaatcac aaataaggat
     1441 ttgtttccag atgaaggaag tctcttaggt attcaacagg tgattcagca atccatactt
     1501 gatcaagcca aagaacctga aaaaatcatt gatgctgtat taacaatgga tagaatttct
     1561 tatgatagta aaatgactta tacacctgat gaattgacta tcgtcttacc aaaaaattca
     1621 actggaactt ctaaagtcac tctaaaatac aaagatattg cgccattcat tgatacagat
     1681 ctggtttcgc aagaaagtat aaaagataca ttacctgcat tagatgaaaa taaaaagtac
     1741 gtcgctctta cttttgatga tggtccaaat aatagctcaa cacttgattt gttgaatata
     1801 ctaaaaacag ataacgtgaa agctactttt ttcatgttag gacagatggt ggatcaaaat
     1861 ccagatgttg caaaacaagt ccacgacgag ggtcatgagg tagcatgtca ctcgtattct
     1921 catccacaat tgaatacact ttcgacagat gaattacaaa gtgaaataaa taaagctaat
     1981 aaagcaattt tcaaggctac aggcgtcttg cctcgcaata tccgtccccc ttatggcgct
     2041 attgacaaaa aaagtgctga aacaattggc atgccaatta ttcaatggga tattgactca
     2101 caggattgga aatcaaaaaa tcctagagca atcaataatg ttgtcaaaca gaatgtttat
     2161 aatggtgcaa tcatcttaat ccacgatatc catcctgaat cagttaaagc cataccaaat
     2221 atgatctcca tgttaaaaaa taaagggtac gaatttgtga cgatcgatca actattgtca
     2281 ggaaaacaaa aaccattgca tcaatatttt ggtatgaatg atgagcgact agtagactaa
     2341 ctgtaattag attgagtggt atttgaagaa attatatttg tagtttcctt atttgatgaa
     2401 aagtcatgta aaacaaatta ataaagagta ttaagtatac taactgttgt aagtatactt
     2461 aatactcttt tagttattaa ctttagttag tctcgttagc gtagcgtacg aaacaaaaaa
     2521 acacgcattt ctgtgcgtgg acgaaatagc tttagcgata aaaaactcct ttcgatatac
     2581 taataatggc tactaaccgc atatcagatc gaaaggagtt tctaatgttt accgacgata
     2641 aaagtgtagc acatacgaga tgtcatattt tctttaccca aagtatcgac gaaaagtgat
     2701 ttatggaaag ttaagagtag gtattggtca gatattaaga aaattgtgtg agatgaaaaa
     2761 tattgaaatc attaaagctc atgttatatt catttgttag taagaataac gtcaaaaatt
     2821 agtatttcca gttttatggg ttactaaaaa gacgtcactg atcaatttag aaaggtaaat
     2881 atattctggt aataaagata gactgaaccc cgtaaaaacc tcattgcaac gaatcaagga
     2941 aagacgcttt tgcttctccc ttgattgggc acattctttg attttgattt ttgatattga
     3001 ttatatcttt taattcgcca tagttattta tacaataaag aactaaattt tctaagaata
     3061 gactttctag attctttatt ttcagctttt actaaaatga agtcatccta tccattttat
     3121 tcaaaacaaa ttttttaata agaaagatct gttctttttc tttgaaggaa aagaaaaaga
     3181 aaacgtgaaa agaaacttat gcaatctata ctgctaataa cctctataag atcgttgtat
     3241 attgatatta ttatcatgtt tattttagga agaatactat gagttaagtt tttaataaga
     3301 aatgtcgagt ttatgaacct tttttcaaag ttgaaaaaat ttctttattt gataatggcg
     3361 atcaacatct tttagaatgg atgcaatggt taaactgatt gttgagtata taatcacttg
     3421 tttgttttta tttatctttt ccccactata tggttaatag tcagccactt tagaaagagt
     3481 tttagctgtt ttttacttga ggaacatcat tttattggca gtcttatttg acttattaag
     3541 tgaatttata ttaaaaaaat tcgtttttac tcataataat ctctactaag attcctcctt
     3601 tatttgagta tcattctcat ttgattataa attaaatcct tccctttatt attatcaacg
     3661 agaaaaaagg ttaaatgaat acaaaagaaa tagatctttt gtgactaata aaaagtgaac
     3721 gttcatattg aaaatattat aaatttaatt taacatataa attgagaaag ggaatctatt
     3781 ctaacctttc ttataaaatg aacgttcgtt tttaggattt ctttttgata actttttatg
     3841 ttaggaggat aaagtatgtt ttatcaaaga agcgagaaga agtttaagta cgcaattaaa
     3901 aagaaaaaag gaggaggtgg agcggcttct ttcattatcg gtgcaatgtt tttaggaata
     3961 ggattaattt cttgtcctac agtttctttt gctagtgaaa caacagagat aaatcaatca
     4021 actgaaatcc aatctacttt gaataattct attctaaaag aaagtaattc agaagaaaaa
     4081 caaaatattg atgtgtcgga agatagtgct ataaataaag atctagaact agcttcgaaa
     4141 gcaaccattt ctgaatcaga aaattcattt ggtgaaacta ctaacaatca agaaaataca
     4201 aatttatctg aagatagtat tgaagttcag ccagagagta ttattcaaaa ggaagtcttg
     4261 actgataatg atgctattca acaattagaa gtacatcctc atgaagatag cgatgatgct
     4321 gctttagttg agaatcagat gacaagagtt acagaagaaa gtataaaaag caatacttca
     4381 caagtagata aagatacgac agttttatct aatacaacaa gggacttagt taatttagaa
     4441 gatactgcta tagaaaatgt tactccacaa aaaacgatca aaaaagatag tatttcttta
     4501 ttagaggaaa ataattcatc atcagcatca agaactttac gtagaagtgt taggagtctt
     4561 gatgttcaaa ctggagaaaa ctttttagaa gattgggcac taccagacaa ttctaacatt
     4621 tctggaagtt tgattactca gactggaatt acttatgtgg gtgtaaaaac tgatgatccc
     4681 actcaattac atttgaaaat ggcttacaga gctgcagcaa cgcctgcttc aattgattgg
     4741 atttatcttc gtgtggatcc agagcttacg aaatatattg aagaaattaa cataaaaaat
     4801 accgtaaaca tcggtgcaca agttgggtac caacgatatt ttgaaaaagt agatactaat
     4861 acattgagca atgtaaatac ttttggaact ccgacaggtg taagtgatgc ttatgcacaa
     4921 gtagatcaaa aaactggcgg aatctatcgt gtgttattag ataaattttt catacgtatt
     4981 ccgggcacga atcctaagag tcgaggcgcg ctatctggaa actggggggt atttccatct
     5041 gttcctctcg aggctgaaag atatgaagcg aatatctata taaaattatc gaaagatgtc
     5101 gcagagttac agcaagagct tggaagggat aagtttggtg ttcaacttcg tttacaaggt
     5161 caatcaagtt ctggtgttgc aactattgct aaagaaagtt taaataagaa tactattgtt
     5221 gatctttcac aagaggagcc agatgaaaat aattcaaatt ggttaaactc accatctgtc
     5281 catacaatta ctaccactta tgaaggaaag caaatgggaa gcgatggtca gttcagtagt
     5341 attctcgaag gaactgataa aagtctgatt agagttcaga atacgatcat gaataacctt
     5401 ttatatggaa cggcacttga tttaggtcga cctgtttcat ttaatattga gattgatcca
     5461 caaatattaa atttagtttc agatgatgat tatattacga tttggcaagt atacagagaa
     5521 aatagtatca accatcatga cggtggatca aatgcacctg tcatgttgaa aaagaatatg
     5581 tttgtagata ataaaataaa aattgaagtc aacaaggata aagctggtca gtatggaaat
     5641 ggagtttact acgttaatgc tgttgagagc tttatgaata ctttgagttc ttcaccattt
     5701 gttggtgcaa actttattga tattcctgtt atgcctaaat ctctaattga agatgaagat
     5761 caattgatat cagcagaaat taaaacatgg tttacagata aaaaaaatga tcaagagaga
     5821 atagtaagaa actcacttgc ttcaagttac attaatttat tccctactac cattaatttc
     5881 tatgattatt caaccaagga tacagaacaa ttattgaagt tacgtgaatc aacctactta
     5941 gtttctacgt ttggtcaaga aattaatgga atggatatgg gggaaacata cgaaattagt
     6001 aattatgagt ttgtgactgc cgatcctgaa agtttaataa tcacacaaaa agatggaaat
     6061 atcattaatt tgtattataa gaaactttct agtgatgctg aattttatga accagaagta
     6121 gaaaaagaag aagtcaacta tggagaaacg attgat
//
LOCUS       DAXLPQ010000093         5963 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.096, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000093 DAXLPQ010000000
VERSION     DAXLPQ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.096"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..1381
                     /locus_tag="ACF3UO_002607"
     CDS             <1..1381
                     /locus_tag="ACF3UO_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFD3658544.1"
                     /translation="CGQFYVNKEVNLEKLSNLLHVCKTTLLNDINNIKKEFEEQIAYT
                     HREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDEPDYLQLTECEFISVSK
                     AYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRLGGFNSWELPESFFERA
                     DRFIESVTENSGRFYDKENKEILLIGFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYV
                     ESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKE
                     LVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQT
                     IFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYIVTNSDVHYLIYREALE
                     AVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIDR
                     AIISAVQNK"
     gene            complement(1473..1838)
                     /locus_tag="ACF3UO_002608"
     CDS             complement(1473..1838)
                     /locus_tag="ACF3UO_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFD3658545.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1835..2200)
                     /locus_tag="ACF3UO_002609"
     CDS             complement(1835..2200)
                     /locus_tag="ACF3UO_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFD3658546.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2392..2640)
                     /locus_tag="ACF3UO_002610"
     CDS             complement(2392..2640)
                     /locus_tag="ACF3UO_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658547.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2639..2767
                     /locus_tag="ACF3UO_002611"
     CDS             2639..2767
                     /locus_tag="ACF3UO_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFD3658548.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2824..4518
                     /locus_tag="ACF3UO_002612"
     CDS             2824..4518
                     /locus_tag="ACF3UO_002612"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFD3658549.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4618..4791
                     /locus_tag="ACF3UO_002613"
     CDS             4618..4791
                     /locus_tag="ACF3UO_002613"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658550.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5169..>5963
                     /locus_tag="ACF3UO_002614"
     CDS             5169..>5963
                     /locus_tag="ACF3UO_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFD3658551.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEK"
BASE COUNT         1955 a         1133 c         1090 g         1785 t
ORIGIN      
        1 atgtgggcaa ttctatgtaa ataaagaagt caatctagaa aagctctcca atctcctgca
       61 tgtttgcaaa accactttgc tcaatgatat caataacata aaaaaagaat ttgaagaaca
      121 gatcgcttat acacatcggg aaaaggaccg ttacacttta tatttttcag aacatatacc
      181 tcgatgcaag atcatgcagc aattgtctca aaattcgttg tttttaaaaa cttgtctgct
      241 ttatttggaa gaagatgaac ctgattatct tcaattaact gaatgtgaat tcatctctgt
      301 cagcaaagct tattcattaa aaaaacaagt attagcttat tttaatgact gcgggatcga
      361 aatcgaccgc tactcccctc gattcactga aatggaaaga cgtctgctgc ttcttaatgt
      421 gtcgtatcgt ttaggcggtt ttaattcttg ggagctacct gaatcgtttt ttgaacgtgc
      481 cgatcgtttc attgaatccg taacggaaaa tagtggcaga ttttatgata aagaaaataa
      541 agaaatctta ttgattggtt ttgctatcag tttcctacgc cagcaagtgt gtgctgtgac
      601 aatagattca aaatttatcg aagaaatcaa aaaacgtcct atttacaatt atgtcgaatc
      661 agcatgggaa aacactgatt tccaaaccta ttataaaaaa gaagaattcg cctttatttt
      721 gacactattc aatctttgta attatggttt ccattcttat cagttgattg cggaagactt
      781 tcaacagcta caccaagtgt ttattgacaa tactcccgaa ataaaagaac tagttgctac
      841 ctttgaatct cacttcaatc aagaattatt cggaaaccaa ccattcgaac gtgcgctgat
      901 tcatctgatg cgttcggctt gggataacta tcaattattc atgccagaaa aattttatct
      961 tctaaatgag gaacagacaa atttatataa agaagtccag acaatttttt ccagctggtc
     1021 cagccagtta ccttatgatc tacggttgaa tcctaattgc atgcgggctt ttgtgatcga
     1081 attgagcgga attctccgtc tgacaaaaga acatctgact atctatatcg tcacaaattc
     1141 ggatgttcat tatctgattt atcgggaagc cttggaagct gtaactactt tcgattttca
     1201 agttgcacca acaatttatt caagtatatc tgatataaag aagtatgcgc agcagtcctc
     1261 aaaccgggta ttatgtgaac gtacattata tacaccagat gcggtccaat atgaaaatat
     1321 tattcctatt tcgatcaata cgatcgatcg agctatcatt tcagctgtgc aaaacaaata
     1381 agggactgtg acaaaaatca tgtcacagcc tcttatttgt tgaagatgcc catttctgta
     1441 acaatctctt gatacacatc aggctcacaa cctcacttat tttggacatc tacgggtccg
     1501 atctctttat ttaaaaaata agaaatgatg gttcggataa ctaccaacgc cgctagttgg
     1561 aaaatatcct gcaaggtagg tttgataatc gattcgatga tcccagctga aacaagaatt
     1621 tccaaactta gaagtatata gcctcccaac atctttttaa tagcattgtt ctcgctgact
     1681 cggtcgcttt gcacttttgt atggacaaat aaatatttca aaaaatcctt gattgataga
     1741 caaacacccc aaaccaataa acagatagca aagatatcaa gtcccagtac aagtttttca
     1801 aaatatggaa gaagaaactg catcaactct gtcgtcatcc tacctctcct cttctttgtt
     1861 tttctttgtc ttctatttcc tgattcaaga aataagaaat gactgttcga atgataataa
     1921 taagtgcaag cttcaaaata tctgtccaag tcggcttgat aactgactcg atgatatcag
     1981 caacgactag tacttccaag cttaacaaaa tataacttgc tagcagtttt cttgtatctg
     2041 cattacgagt attacgttct gcatagtttt tcttgacatg agaccaatca aaaagtttga
     2101 atagaacaag aacgatcccg acaattaaga taccgataga acaaatattt aaaatagcaa
     2161 tgatccattc tagaaattca attaaatttg agcgaaacat atacgctacc tactttcttt
     2221 taatttgttc ctattctttt attgtaaaag aaagttacct tgttcgtcta tttaaaagtt
     2281 gttctaatga taacggttcg cttaaatttt tctttttcac tctccccttt ttctccctcc
     2341 atccataaat cgtggaagta tccaaaacaa cgtagcaagt taaaataagg cttagtccgt
     2401 catcagcttt tcaaagaagc actgtctcgg tgcttttttt gtacccaaat ttctaaaaat
     2461 agaaccatac acctcctcaa atcttttctt cttacctacc ctatttttat ttacaggaaa
     2521 atcagacact tcttcttttt tgtcaaaatt tcctttttct tctcgtccta tcatttggca
     2581 ttctaataaa aacgaactat ccttggatat agaaagagaa aacaaggagg cgtttttcat
     2641 gagtaaaaaa ttaatcaaag tcggcatcgg tttaggtttg cttgcccttg gcgctgcata
     2701 tctaggaaaa aagacaggac tattcgaaga tgacagtcat ttatatgatg aattcgaatc
     2761 aatctagcat cctatttagt tgaatcacta cggacatact tggaagacat tggaggaatc
     2821 acaatgagaa aaagtaaagc aataatgatt ggtgccggta ttgccaatat ggcagcggct
     2881 gtttatttga ttcaagaagg caaatggaaa ggggatcaga tcacctttta ttcattggat
     2941 gatcacggtt caaatgatgg tgcaccgacc gacactgtag tggatgaata ttggaataaa
     3001 aaccatccat tagaaaacca aaaaggctat attgctcgag gcggtcgcat gcttaattac
     3061 cgtacctatg tagatttgat ggatctgtta agtcgaatac cttctgttac tgagccaggg
     3121 atgactgctg aagaagatac gagagatttt gatgcaaaac accgaacctt tgacaaagca
     3181 cgtttgatgg aaggtggcaa aggaatcatt gatggcggaa aactgggatt caataataaa
     3241 gaccgtattc ttctgactaa actgattgct atgcctgatt cagaagaaga aaaactagac
     3301 aatatcacta tcgaagaata tttcaaagat gatccacact tttttgaaac aaacttctgg
     3361 tttatgtggg aaacaacatt tgctttcaga acacgtagtt ctgctcaaga attgcgtcgc
     3421 tatatgcatc aaatgattta tgaattcact caaatcgaac atctagtggg cgtcaatcga
     3481 acacgttaca atcaatacga aagtattatg cttcctttga tcgagtactt gaaagaacaa
     3541 ggatgcaaaa tcattttgaa ccgccgtgtc actgactggg aattcaaaga aacaccgatg
     3601 caagatgaaa tcactgtgac tggtttgaaa atgaccaata cactgactca agaagaagaa
     3661 cacgttgtgg tcgatgaaga tacagcagtt attttcacta atgggtccat tacagattca
     3721 gctactttag gagattacga aacaccagct gtagaaaata tggattatgg tgcagcttct
     3781 agtctctgga aaaaagccag tgaacgtttc tacaacttgg gaaatcctga caaattcttt
     3841 gctgatcgag atgcaagcga atgggtcagc tttaccctga cgacgaaaaa ccatttgttg
     3901 ttgaatgaaa tcacccgtat cacgactcaa gaaccaggaa atgccttgaa ttcatttatt
     3961 tcaaccacac cgatcacgcc gttaggccaa aaagatgtca atatgtctat cgtcgtgcat
     4021 catcaaccgc attttacgtc tcagaaacca aatgaaacag ttatttgggg ttatttcctt
     4081 tatccaagac gacgtggcga atttgtggat aaacagtata ttaaaatgaa tggaaaagaa
     4141 atgctagaag aactgattgg acaactttca aaagtagatc ctggaccagt gaatattcgt
     4201 gaaaaagaaa cagaaatttt cgacagcgta ataaataata tccctgtcta tatgccttat
     4261 gcttccgcgt tgttcaataa tcgtgccaaa agcgatcgac caaaagtcat tcctaaacat
     4321 tcgaccaatc tggcctttac aggagaattt gtcgagcagc cttatcagat gatctttact
     4381 gaacaaagtg ctgtacgttc tggagaaatc gctgctttcc attttgcggg tatccctatg
     4441 tcacgtcttg tcaaaacacc gcgttacgac aaagatattc ctactctagc tcgtgccgca
     4501 aaaaaaatgt ttgaataatc aagaggttgt gaaaaagctg ccctgcatca agtaataaga
     4561 acaaccaggc taaaacagct tcttatgttt ttgatttggt tggacttatt accgcagatg
     4621 caagcttttg aacaccgttt accaagaggt tgtgaaaaag ctgccctgca tcaagtaata
     4681 agagcagcca agctaaaaca gcttcttatg tttttgactt ggttggactt attaccgcag
     4741 atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aagtcgttta gtttcgagta
     4801 tgaagaaaaa ttttgtgaaa atggttcctc acgtttttgc ataaatttga cttaataccg
     4861 agaaactgat cccttctgtc ataacctctt tttatttatg tctgtttctt tttgaaaaca
     4921 accatttttt caacgtttac tctcttgcca atccaacatc atctaacaga tacaactatt
     4981 tcaatgatta ccattacact aaaaaatcgg aaactcacct ctccgaacac aaatacataa
     5041 gactatagaa tgtttcattt aagaaaaaaa gcgtttcatt atcaaaaagg taagatctcc
     5101 tttaaaatga aattatctgt agtactaata atgcagacaa ttttatgaat ctgaaaggag
     5161 catctccaat gaaagcagtc acttggcaag gaaaacagaa aatggaaatc agaaacgtag
     5221 atgatccaaa aatattagaa ccaacagatg caatcatccg tatcacagca acagccattt
     5281 gcggctccga tctgcatctt taccatcatg gtgaagcagt tttggaaaaa gggtatgttg
     5341 taggacacga accaatggga atcgttgaag aagtgggatc tcaagttcaa acattgaaaa
     5401 aagggcaacg tgtggttatc ccttttaata ttagttgtgg tcattgtcat ttctgcctga
     5461 atcacatgga aagccaatgt gatgaatcaa atccagatca gttatatggc gggcttttcg
     5521 gatttggcaa gttgaacggt aatcattggg gtggtcaagc ggaatatcta agagttcctt
     5581 atgcagactc tacttcattt gttgtaccag ataatgatct tcctgatgaa aaagttttat
     5641 ttctatcaga tattttgccc acagcttatt ggagcgttga aaacgcagga gtaaaaaaag
     5701 gcgatacagt tgtgattcta ggttctggtc cagtcggtct attcgctcaa aaattcgctg
     5761 ttatggctgg agcagagcgc gtaatcgcag tagatccagt acagcaccgt ctagataaag
     5821 cggctaatta caatggggtt gaaacttatt tcttagaaga cacggcacaa gctggaacag
     5881 aattgtatga actggctaaa ggtggcgcag atgtcattat cgattgtgta ggaatggacg
     5941 gattagagcc tgtcaaagaa aaa
//
LOCUS       DAXLPQ010000094         5952 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.097, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000094 DAXLPQ010000000
VERSION     DAXLPQ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.097"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(289..2955)
                     /locus_tag="ACF3UO_002615"
     CDS             complement(289..2955)
                     /locus_tag="ACF3UO_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3658552.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            3297..4748
                     /gene="cls"
                     /locus_tag="ACF3UO_002616"
     CDS             3297..4748
                     /gene="cls"
                     /locus_tag="ACF3UO_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFD3658553.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            complement(4953..5768)
                     /gene="thiD"
                     /locus_tag="ACF3UO_002617"
     CDS             complement(4953..5768)
                     /gene="thiD"
                     /locus_tag="ACF3UO_002617"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFD3658554.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         1708 a         1283 c         1055 g         1906 t
ORIGIN      
        1 tcttttgatg aataataaaa tgattggctt tccgtctatc ataaataaaa aaagggactg
       61 tgaccaaagt cgtgtcaaag tccctctttc cgaataaaca gtgtccaatc agatgaccct
      121 cagtattagc tcaaaatgct gattttacaa cttcttcctt aaacggtgtt ctcctgccaa
      181 ctcttcggtc acaagtcaca atattcaaca aacatgagaa gctgtttgtt gaaattgcac
      241 cttgtgactc agaattaaac ggcaggctca caacctcgtt gattcgtttt atttatttcc
      301 ttgtactcgt acaatgatca atttagtgat ttccatcaaa acaattgtca caagtgcgat
      361 tcccatacat gtaaagactt ctgtcaatcc aaatgctgat gggatagaga agacttcttt
      421 cagtcctggg atcattgtta agcagtaaag cgcgctacat acaactacag ctagtaagac
      481 acttctgtta gagaagaacc ctgcttggat agctgtttgt gtgtttgaac gtgctgggaa
      541 tgtttgcaat gtccgacacc aaatcaatgt tgaaaatgac atggctacac cgaattcagg
      601 tgaatgctgc atgccaagcc attgagcaaa gataacagca atcccaatca gcacaccacg
      661 atacgttaca gaaatcaatg ttttgtccgt aaagattcct gaatttggat ctcttggcgg
      721 gcggttcatc gtagcaggtt cagctttttc tgtacctaat gcaattgctg gcagtgaatc
      781 attgactaaa ttgatgaaca acagttgtaa tgctgtaaat ggattggacc agtcagcaac
      841 taaggcaaag atgatcgcaa tgatcgcacc taaatttcct gcaaatagat aagaaatagc
      901 tttcttgata ttatcaaaca cattacgtcc tacttctact gcgctgacaa tagaagcaaa
      961 gttatcatcc gtcaatacca tcgctgctgc atcttttgcc acatctgtac ccgttcccat
     1021 agcaattccg atgtctgctt gtttcaatgc tggtgcgtca tttacaccat cacctgtcat
     1081 agctgagata tgacctttat tttgccaagc acgaacgata cgaattttat tctcaggtga
     1141 aacacgtgca taaacagtga ctttttctaa aacttcgttt agttgatctt ctgtcaattc
     1201 atctagttcc gtcccggtca aagccaggtt tccttcttca aaaatcccga tttgttttgc
     1261 gatagcaaca gctgttgttt tgtggtcacc agtaatcatg attgttttga ttcctgcact
     1321 tcttgcttct gttaccgcct gagtcacttc agcacgtgga ggatcgatca tagcaagcaa
     1381 accaacaagg atcaaatcgt cttcatcttc aaatgataaa tcaaaattat caagtggacg
     1441 gtaagcaaaa gctagtacac gtaatgcgcg tgttgaaaaa gcttcatttt gctcttggaa
     1501 ttttttcatc aattcatccg tcatcggaac gacttcacca tttagcaata cttttttact
     1561 gcgttggaag acgatatctg gtccgccttt gacaaacaag taattttcgt tatcgatcgt
     1621 gtgtccagta gacattaatt ttcgatcaga atcgaaagga agttctgctt gtcttgggta
     1681 gttgtttcgg atttcctgat aaggctggtt taatttttca ctaaagtcga taaacgctac
     1741 ttccgtaggg tcgcccaatt tagtaccgtc ttcactgatc gatgcatcat tcgctaaaac
     1801 actgatttcg atcaagcgac gttcgtcagc tgtccatttt gaagggtcat ttgtgaaatc
     1861 cccagtatcg ccattaccta aaaagtagtc aacaactgtc attttgtttt gtgtcaatgt
     1921 accagtctta tctgtacaga tgatacttgt cgaaccaagt gtttcaactg ctggaagctt
     1981 ccgaataatg gcatgacgtt ttgccatttt attcgttccc aaagataaca cgattgttac
     2041 gatagactgt aatgcttctg gaatagcagc tacggctacg gctacggcaa acatcactgc
     2101 gctgacgata tctgcagtca tatctcctgt accttctcca agataaatac gaaacagttg
     2161 gatacctaaa atcaataaag acaatgccaa aatagccaga cttagttttt tactgaattt
     2221 atccagacct cgttgtaacg gagtgacttg ctcagttgtt gattccaaaa ggccagcaac
     2281 ttgtccgatc tccgtattat tcccagttga agtcactaag aatttaccgc gtccgtaagt
     2341 tacgatcgtt ccactgaata ccatatttgt acgatctccg attggtaccg tacttgtgat
     2401 atccgttact tctttttctg cagaagtcga ctctcctgtc agcatacctt catctacttt
     2461 taatgatccc gcatctagta aacgtccatc agcaggtaca taatcgcctg cgtctaacaa
     2521 cacgatatct cctaccacaa gttcgtttgc cggaatcgtt ttttccttac catcacgaat
     2581 cactcgagca tcgggcgctg aaaggttttt caacgcttct aaagaacctt ctgctttttt
     2641 tgtttggaca acactgatta tagaattcaa catcaatact gcaaaaataa ctaagaattc
     2701 gatgtagtca cccatgacca tctgaatcag tgcgacaatc agcaatacga taaccattgc
     2761 atctttgaaa gtttctaaga acaatttcca agttggcttc ttcggctttt cttttagctg
     2821 gttcaagcca tctctttcta atttttcctt cgcttgcgtg gtgctcaatc catcggttga
     2881 gctctgcgtt tgctgcatca acgagtcgat cgtttcttta tagaccgctt gttgtgcttg
     2941 ttccttgttt tccaaatttc atcccccatt ttttgatctt ggccctagtc ctgtctgaaa
     3001 aaaaaagaga cctaagacaa atacgcattt gtcttaggtc tcaccatttc atacaatacc
     3061 agaaaaccat ttggttaact tactgttgat attatcgcaa caaacgttgc cggttactcc
     3121 cctaaggaga tattcaactg tactaatatc ctaccttatt aacctacaaa aagcaactac
     3181 tttagcccga tttacctaca ttttcatgaa aggagtgaaa agtatattca ccttggtagg
     3241 cttctttctt ctatcatgct atactaatgt tattgtatgt aaggaggaac atttttgtgg
     3301 tatctagtat tataaccgcc ctttatctat taaatgcact tattgctttg gtggctattt
     3361 tgatcaaacc ccgagatgta gcagccattt gggcatggct cttagtattg tttgcccttc
     3421 ctggggtggg ctttgtatta tatttatttt tcggacgtgg attaacggat aagaaaaaat
     3481 tctatctccg acaaagtgac ttgaaagaat tagaaaactt tcagtctttt agaggagata
     3541 ccattgaaca ttacgatcct gacatgggcg ataaagacaa acagcaattt gtcgacttct
     3601 tctcttcatt aaatcgtatg ccgctgacaa gaatgaattc tgtcactctt ctcacagacg
     3661 gacaagagaa attggattca ctgcttcaag atctaaaaaa agccaaacat tcgatccata
     3721 tcgaatatta cgcatttgtg acagataata tcggccagca agtcttacat gttttagaag
     3781 aaaaagccgc agaaggcgtg gaagttcgaa tattatatga tgcatttggc tctcatggta
     3841 caaaagcaaa agatttcaat cgtctaatca aaaatggtgg acatgtccat acatttgtta
     3901 cctcacaaaa ggcattactt cgtttccgat tgaattacca tgatcaccga aaaatcgttg
     3961 tgatcgatgg aaagattagt tataccggtg gtttcaatat tgccaatcaa tatgtaaata
     4021 caacaaaaaa attcggctat tggcgcgata cgcatatacg gattttcggt gccgcttctt
     4081 ctttgctcca gcttcgcttc ttaacagact ggaacgtctc ggtacctgaa gaaaaaaagg
     4141 tcggctatca tttgaattat ttctttaaaa aagcagatcg agatgaatct aagcttgctg
     4201 atacatccat ccagcttgtt tcaagcggac cgaataacga aagggaacaa atcaagcttt
     4261 catttatcaa attgattact tctgctaaaa aacgtgtttg gatacagaca ccttaccttg
     4321 ttcctgatga aagtgtcatt gctgctttaa aaatcgcaac tgcctctggt gtagatgtga
     4381 aaatcatgat tcccaacaaa ccggatcatc cttttattta tcgagcaaca caatattatg
     4441 ctcggcagct gatcaaggaa aatgtacaaa tccttgtcta tgagaacggc ttcctccatg
     4501 caaaaacatt gataatggat gatgaaatct gcatggtagg ttcagcaaat caagatattc
     4561 gtagctaccg attgaatttt gaaacaagtg ctgtcattta cgatcctgag tttttagaag
     4621 aacttgctac tcagttcaaa gaagatgaga cacattgttc atccatgaca actgaaacag
     4681 tcaaggaaat gtctaactgg ctattattca agcaacaaat ttctcgatta ttttctccaa
     4741 tcctataatt tttttattca agtagagaaa aatatactaa gattaaaggg actgtgacaa
     4801 aaatcttgtc acagtccctt cttccgaaca aacggtgttc tcctgccaac tcctcggtca
     4861 caagtcacaa tattcaacaa acatgagaag ctgttttttg aacttgttcc ttgtgactcg
     4921 gagctggacg gcaggctcac gacctctttc ttttactcta attcaccagc tgcccaatga
     4981 ttgatgggtc catatttgtg ccctacattt atttcttcac gaattgcacg gtttacatag
     5041 tcttttgcca atcggatcgc ttgttcaact gtttttcctt tcgctaactc agctgcaata
     5101 catgcagata gcgaatcgcc agttccgttg atccggtcgg taggataaaa tggtgcattt
     5161 aaccaaaacg attttcctga ttcgagcaat acgtagtcat tgactgtttc ttgctgcgca
     5221 tctttagcat gatgtccttt gatcataacg ttttttgcac ccatatcttg cagttctttt
     5281 gctgcttgca caaaatcttc ttcagctgct aatgtccgtc cagtcagctt ttctgcttca
     5341 taaaaattag gtgtcagtac ttcggccaaa gggacaagct tttctttcaa gctttgcaaa
     5401 gcagattctt ctagtaaaag atttccatgt ttcgttacga ttacgggatc cacgactaat
     5461 ggtccaaaat catatttttg gtaatttttt acaactgtct caatcaactt tgaatctgct
     5521 agcatacctg ttttagctgc acgtatttga aagtccttcg caatcagttc aaattctttg
     5581 tcgataaaat ctgttggcaa tgtcacactt gctccgattc cgtaagaatt acctgcaaca
     5641 catgcggtca tgacagaaac accgtaaaca tttcttgtaa agaatgtatg catatctgct
     5701 tgcatccctg cgcttccatc gctatctgat cctgcgatcg tcattgcttg tacatactga
     5761 tcttccatca aatcgattcc tccattttta taaaaagatt tttcataatg ctgttactgt
     5821 ttctatcata tgtttttcaa agtatccctc agtaaatata ccactacctt ttcttggtaa
     5881 tcaaatttat ttgaaaaaac atttgtaata aatcagaaaa tagttgtcat ttgtttgtat
     5941 tcgctattct aa
//
LOCUS       DAXLPQ010000095         5912 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.098, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000095 DAXLPQ010000000
VERSION     DAXLPQ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.098"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(99..1229)
                     /locus_tag="ACF3UO_002618"
     CDS             complement(99..1229)
                     /locus_tag="ACF3UO_002618"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFD3658555.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACF3UO_002619"
     CDS             complement(1878..3080)
                     /locus_tag="ACF3UO_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3658556.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACF3UO_002620"
     CDS             complement(3140..3343)
                     /locus_tag="ACF3UO_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFD3658557.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACF3UO_002621"
     CDS             complement(3485..4552)
                     /locus_tag="ACF3UO_002621"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3658558.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACF3UO_002622"
     CDS             complement(4610..4717)
                     /locus_tag="ACF3UO_002622"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658559.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACF3UO_002623"
     CDS             4880..5692
                     /locus_tag="ACF3UO_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658560.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1748 a         1219 c          949 g         1996 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgggctct ataatttatg
     5881 ggactgatga atcagaattg attcttcagc cc
//
LOCUS       DAXLPQ010000096         5809 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.099, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000096 DAXLPQ010000000
VERSION     DAXLPQ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.099"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            450..1604
                     /locus_tag="ACF3UO_002624"
     CDS             450..1604
                     /locus_tag="ACF3UO_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="HFD3658561.1"
                     /translation="MIILKPKNKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1577..2020
                     /locus_tag="ACF3UO_002625"
     CDS             1577..2020
                     /locus_tag="ACF3UO_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658562.1"
                     /translation="MGQYHYKLVNKPIVLVMGLVLVLFLTSCSKKQEIQKTELIPFLG
                     TWQTKDHSERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNL
                     LTLRSNKKQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            3143..4075
                     /locus_tag="ACF3UO_002626"
     CDS             3143..4075
                     /locus_tag="ACF3UO_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFD3658563.1"
                     /translation="MANEIVKYKPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFDQLKDLSAYKQTAGEVFIKDLTRTYDHLMDLRFGKKSNGGLTIERFTMFTDFEIH
                     GEADNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRTKLFNIEHNGELTQEEKWRAKDRILDLPLGTHEAN
                     FKKQQQTEKEEVEKQTLSNELKQDLLGNLQNLFD"
     gene            4092..4607
                     /locus_tag="ACF3UO_002627"
     CDS             4092..4607
                     /locus_tag="ACF3UO_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3658564.1"
                     /translation="MADKTIKDLAEELGVSKTAINKKVSDENRKLWFAKIGNKFVINE
                     IGQKAIKSMFFTENENSNQQPVGEKSKTENHKNANQVSELELFFFLEKQLNQKDIQLQ
                     EKDEQLKQMQKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQ
                     NKEKKWWQFWQ"
     gene            4903..5184
                     /locus_tag="ACF3UO_002628"
     CDS             4903..5184
                     /locus_tag="ACF3UO_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658565.1"
                     /translation="MDILVRNINPKIITRVDKRCQELTTKTGEKWSRNKYLKVLIESD
                     FDRQLMNYKKEQFDLLLEKFIDIQTKNTETLNDYVHTNNQLIETLIGGI"
     gene            5186..5602
                     /locus_tag="ACF3UO_002629"
     CDS             5186..5602
                     /locus_tag="ACF3UO_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658566.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EKQLNPSQRNQPKNRQKETSQTFTSKNFDPTNFLKR"
BASE COUNT         2227 a          961 c          931 g         1690 t
ORIGIN      
        1 aaaaaaaaag actgctcgaa agagcagtct caagcaaaaa ataaacgaac aaacgcaatt
       61 actcacgaac acaaacaaat acaataaaat acctaaataa tgaaaataag tgataaaaaa
      121 caagggtatt tatagtttaa caagcgctca taaaaataac aagtctttaa aaaatgacag
      181 ataaaaatgc acaaagaatc ggacacagat aaccgcgaaa aatcaagctt tagaaagttg
      241 tttttagcta gaccaatgaa aaatcacaaa gtccgcccct gtatccgttg gtagaggggc
      301 tacttggttt agtgtacatt atgttaacta gctcgttaaa taacgattat gttcccaaaa
      361 caatatttta tgaactataa caaaaatttg ttatcgcata ttgtatattt taattatagg
      421 tgtatatcac ttaattttaa cacaaaggcg tgattatttt gaaacccaaa aataaaattt
      481 atctaggtct cctcttttcc ttgatgattg gaatttttag tataggaatt acaaatacct
      541 atgcttcaga aaattctaat ttcaatatca actcccaacc aattgaagaa caagcaatta
      601 attttgcgaa aactgatttt gaacactcca taacttcaat tcttttaatg gaaaataaca
      661 ctgaaactga tattaactat actcttggtt cgccatttaa aatgctcgat ggagaaaata
      721 cggcaaatag ttctattttc tttccagtat tttcagacgc tgataatacg attaaatatg
      781 tttataccgt caaaaaaaat acaaatggag aatattcagg aagtatttca caatttttag
      841 caaaagaact tcaaaatcta gtagatagca atataacaga tacaacctta ttttttcaag
      901 ataatagcat ttattattcc gataatggcc aaattaaact actttggaaa tcacctttaa
      961 gtacagaaaa aaatggtgtc tcttccttta cagaaaaaaa tgatcttata tccgtaaata
     1021 taaaaaataa aattaaaaat ttctctaaaa aacaaaattt tcctgcggtt aaacgtgtaa
     1081 aaagtgtctc ctccggagat aactttatta tgattaattg gcgtatagca gaaacccaaa
     1141 caagttttcc gtggtgcgct gcttacgtag aagctgctat cttatgtaat aaaacagatg
     1201 tacgcgctac ttcagctaga gccattatgc attataccta tcctaattta aacaacagtc
     1261 aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat tactgtggtg
     1321 tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca caactaagaa
     1381 aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac agccgtcatg
     1441 cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat gtgtggaatc
     1501 cttggtataa ctacccaact gtaataagtg caaatgcagg gccagttaca attcctgtac
     1561 ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac ccattgtttt
     1621 agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac aagaaataca
     1681 aaagactgag ctgattcctt ttctaggaac ttggcaaact aaagatcact cagaacgtct
     1741 agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct tagtaaaaga
     1801 gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac aagttttcat
     1861 ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat tagattacac
     1921 ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg atgggacaga
     1981 agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg tttgatatta
     2041 caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt ggctagcatt
     2101 tgctagcctt ttttgtattg cggagcgtga gttttgaggg ggattcaagg gggagtttct
     2161 cccctttgac aagcggttat ttgcaccaaa tacgaaggta tttggctagc aaatatagag
     2221 cttgccaaac cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca
     2281 aacgatacgt cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat
     2341 ttggctagca atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt
     2401 cgagtgagcg aatccgaatt tgcaaatctg aagctttgca aatgagtgtg ccggcttccg
     2461 taaaagtcta ggtaacatta gtcgatatat acataaggct ctaatttgcg ttttaaggcg
     2521 ttttaaacgt tctggtatgt aatttatacc aaagcgactt taaaacgcct taaaacgaat
     2581 tttataggtc ttgtaggacg tttcagggtt gttagggctt gccctgaccg cctgtaaggc
     2641 gctttaaaaa caagataagg gattttatct agacttgtct taaaacgccg tagatgagcg
     2701 ctcagagctt cttaaaggac tccttacgaa ctgtttttaa gcaaaggagc ctttaggcga
     2761 ctgcgcagtt caatgtgaga gcgtagcgat cacaccttta aagcgaccgt agggagcaga
     2821 ttcccagttt aggaaatttc gcgaacctgt ttggagaaaa aaagtaggaa atttttaggc
     2881 gggaaatttt gcccccctct tttataatct cttttataac ctctttttaa acctctttac
     2941 cgtcggctgt atccttactc tcccaaggcc tgtagctttt ttagggcatg aaattatctg
     3001 tttataggca tgaaattatc tgtttatagg catgaaatta tctgtttata ggcatgaaat
     3061 tatctgtttt aggtattgtt ttaagacata atatacctta aaattatgtc aataaaatta
     3121 gttagactgg agtatcaaat aaatggcaaa tgaaatcgta aaatataaac cagaattaaa
     3181 taccattcct ttaaggaaat ttactccaat agaaatgaac ttgttttttt ctattgtttc
     3241 tagaatgcgt gataaaggta atcaaaaaat acgcttttat ttcgatcagc ttaaagattt
     3301 aagtgcttat aagcaaactg ctggagaagt ctttataaaa gatttaacaa gaacatacga
     3361 tcatttaatg gatttacgtt ttggaaaaaa aagcaatggt ggattaacca tagaacgatt
     3421 tacaatgttt actgattttg aaattcatgg agaagccgat aacccttatg tggatataaa
     3481 agttcacgaa aaagctttgc ctttacttaa caatttagaa agttgggtac gtttctcttt
     3541 aacagaattt cgagatttaa atagcagtta tgctaaaaca atgtttagat tactaaaaca
     3601 ataccgaaca caaggatggg ctgaattttc caaggaagat tttttagaac tattagatat
     3661 tcctaaaagc tatagacaaa caaatataaa tcagtttgta ctcaaaccca taaaagaaga
     3721 actcacacca ttatttaaag gattaacgat tcgtaaaaaa tatggtaaag gccgaggcaa
     3781 acctgttatt ggttatcgtt ttacttggaa agctgaaatt aatcatgctg acgatttttc
     3841 aaaagggaag caagaagatt tacgtacaaa attatttaat attgaacaca atggagaatt
     3901 aacgcaagaa gaaaaatggc gcgctaaaga tcgaatacta gatcttccgt taggtactca
     3961 tgaagctaat tttaaaaaac aacaacaaac tgaaaaagaa gaagtggaaa aacaaacact
     4021 ttcaaacgaa cttaaacaag atttattagg aaatttacaa aacttattcg attaaagtat
     4081 aaggagtatt tatggcagat aaaacgatca aagaccttgc tgaagaatta ggagttagta
     4141 agacagctat taacaaaaaa gtttctgacg aaaatcgaaa actttggttt gcgaaaatcg
     4201 gaaacaagtt tgtgattaac gaaatcggtc aaaaagctat aaaatcaatg ttttttaccg
     4261 aaaacgaaaa ctcaaatcaa caaccagttg gcgaaaaatc gaaaaccgaa aaccataaaa
     4321 acgccaacca agtttccgaa ttagaactct tttttttcct agaaaaacaa ttaaatcaaa
     4381 aagatataca gctacaagaa aaagacgaac aattaaaaca aatgcaaaaa ttactcgacc
     4441 agcaacaaca actcacctta caagccaatc aacaaatcaa aaaacttcac gaacaactcc
     4501 agctaaccta tgcagaagaa tcttcagaaa aagaacccct ttctgttact gaagaaactc
     4561 aaaaaggaca aaacaaggag aaaaaatggt ggcaattctg gcaataaccc aacaattttt
     4621 attcataaaa attgttgggt tactttcttt ttttgctttt acaagcatag cgacatgatc
     4681 tcacgtcgct attttttaaa gagcataagg aaacgcggta tcactttctt acgaaaggtg
     4741 ctaggtaggc tgtgcctacc acgtttctaa gaaaaaaatt tgctatcact ttttcgccat
     4801 tgtggctagc ttatgtatag tatttcggta aaaaacagct atacaaatac tatatttgta
     4861 tgatatacat aaattataca cacataagaa aggacgtttt ctatggacat tttagttcga
     4921 aatatcaatc caaaaattat tacaagagta gataaacgtt gtcaggaact tacaaccaaa
     4981 acaggagaaa aatggagtcg aaataaatat ttaaaagtgc taatcgaaag tgattttgac
     5041 cgtcaactta tgaattacaa aaaagagcaa ttcgatttat tactcgaaaa atttatcgat
     5101 attcaaacaa aaaatactga aacattgaac gactatgttc atacaaacaa ccaactcatt
     5161 gaaacactta tcggaggaat ataacatgag aaaaacttct gttcaaaaac acgttaccct
     5221 ttatcccagt cacattgacg ttttagattc catcatcgaa aaaaatccag atatcaataa
     5281 ctactcggaa gccattcgct ttttatgtat gagttatgaa cctgatacca atacaacaac
     5341 taccagtaac caagccaaac taaatgcgat gggaaaagaa atttctatca tgaccgaaat
     5401 tatcgcagaa tttgctgatt tgtatttaaa agatacaggc gttcttatcg gtacaaactc
     5461 gaaagtatat caagaagtaa aagaaaaaat tgaaaaacag ctaaatccct cccaacgaaa
     5521 tcaaccaaag aatcgtcaaa aagaaacgag tcaaacattc acttctaaaa atttcgaccc
     5581 aaccaacttt ctaaaaagat aaaaaaataa accaggaaat ttttaatttc ctggtttatt
     5641 ttctagagag cggtcttcca ataagatttg caaatcgatc ccaatttgcg taaaaaaaaa
     5701 gctgctcgta cgagcagcta aacaagaaaa agtcagcttg ttttaagggt aaaataagtg
     5761 taacaaattt tgcgaatgca acgatctttt ttattatacg caaacaatc
//
LOCUS       DAXLPQ010000097         5689 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.100, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000097 DAXLPQ010000000
VERSION     DAXLPQ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.100"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(488..1297)
                     /locus_tag="ACF3UO_002630"
     CDS             complement(488..1297)
                     /locus_tag="ACF3UO_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3658567.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="ACF3UO_002631"
     CDS             complement(1297..2043)
                     /locus_tag="ACF3UO_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3658568.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="ACF3UO_002632"
     CDS             complement(2061..2528)
                     /locus_tag="ACF3UO_002632"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3658569.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="ACF3UO_002633"
     CDS             complement(2528..2938)
                     /locus_tag="ACF3UO_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3658570.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="ACF3UO_002634"
     CDS             complement(2949..3962)
                     /locus_tag="ACF3UO_002634"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3658571.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="ACF3UO_002635"
     CDS             4179..4913
                     /locus_tag="ACF3UO_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3658572.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="ACF3UO_002636"
     CDS             4897..5607
                     /locus_tag="ACF3UO_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3658573.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          942 g         1720 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgcttt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAXLPQ010000098         5450 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.101, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000098 DAXLPQ010000000
VERSION     DAXLPQ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.101"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            118..1014
                     /locus_tag="ACF3UO_002637"
     CDS             118..1014
                     /locus_tag="ACF3UO_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3658574.1"
                     /translation="MIQYYYIKKEWGVVMEKEELKILEELRRILNSKNEAIVILNNYF
                     KGGVGKSKLSTMFAYLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
     gene            1106..1321
                     /locus_tag="ACF3UO_002638"
     CDS             1106..1321
                     /locus_tag="ACF3UO_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFD3658575.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            1339..1611
                     /locus_tag="ACF3UO_002639"
     CDS             1339..1611
                     /locus_tag="ACF3UO_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFD3658576.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            1613..2476
                     /locus_tag="ACF3UO_002640"
     CDS             1613..2476
                     /locus_tag="ACF3UO_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFD3658577.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISAKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKLESLQPPIP
                     PIPKTPKLPGL"
     gene            2913..3230
                     /locus_tag="ACF3UO_002641"
     CDS             2913..3230
                     /locus_tag="ACF3UO_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658578.1"
                     /translation="MEKTKKLQLEDFTENEFFGTQEQQYLKAQVREELKEQGFIIDSS
                     FEGDFKTWIGVYARPKDKPTYLDPQNDKEAEEQEQYSINGFKQDFSEWFEWEIKNLKI
                     KEM"
     gene            3269..3766
                     /locus_tag="ACF3UO_002642"
     CDS             3269..3766
                     /locus_tag="ACF3UO_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFD3658579.1"
                     /translation="MKYIKNVETLEELKKAYKKLALKLHPDCGGSNEEMAQLNNEYDE
                     LFVKLKNTHKNKDGETYTKETTETPEQFKDIINQLFNLKMDGVSIEIVGTFIWLTGNT
                     KPYKDDIKALEFRYSPKKYAWYKAPSDYKKRSRKNYDMDTIRGMYGSQKVKEDKEEKK
                     YLQAN"
     gene            complement(3856..4047)
                     /locus_tag="ACF3UO_002643"
                     /pseudo
     CDS             complement(3856..4047)
                     /locus_tag="ACF3UO_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            3971..4243
                     /locus_tag="ACF3UO_002644"
     CDS             3971..4243
                     /locus_tag="ACF3UO_002644"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658580.1"
                     /translation="MLNALELNRGFLFLWSFSLKIILARKNGTLLEALRAELPAFEQT
                     IVPEFKGAVRAVLKKIHRPSIGVKMGEIANYSSTSSPMGQLKKMFG"
     gene            4414..4992
                     /locus_tag="ACF3UO_002645"
     CDS             4414..4992
                     /locus_tag="ACF3UO_002645"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3658581.1"
                     /translation="MKTKDLIIEEFIKSFGENGFEGTSVDYLAKQVGIKKGSIYTHYS
                     GKNEIFTIACEKILDKCIVAIKQLLEVERDKPLDEQLFILLKTVCLESDFLTADEIAF
                     SKRVAILSSSELLSLVDKLLAKYDNFIDDTVSRIFIDCAKQKMLAEEEITSAISVYRM
                     LLENLYIDSLANQNCNEKLNHLWRYFWKGVCS"
     gene            5024..>5450
                     /locus_tag="ACF3UO_002646"
     CDS             5024..>5450
                     /locus_tag="ACF3UO_002646"
                     /inference="COORDINATES: protein motif:HMM:NF018410.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HFD3658582.1"
                     /translation="MEIIKYIGAAFSTWFIGFFPYFEIYIAIPAGFAAGLNWFDAFLW
                     ASLGNWMVIPFVDICYEWLMKFNFMKKIMEKSLNGKWENRIEKHGAWVILLLTPLAGV
                     WTIGVIAKALKFNRAKLWIYSATSVGITGLIITILIINGI"
BASE COUNT         2114 a          786 c          993 g         1557 t
ORIGIN      
        1 tctttttcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcacaag tgattaatca caaatcactt gtgatttgtg attcctaatg
      121 atacaatatt actatataaa aaaagaatgg ggcgtagtta tggagaagga agaactaaaa
      181 atacttgaag aattaagacg tattttaaac agtaaaaatg aagcaattgt tatcttaaac
      241 aattatttta aaggtggtgt tggaaagtca aaattatcga ctatgtttgc ttatttgaca
      301 gacaaattta atttaaaagt tttaatgatc gataaggact tacaagcaac attgacaaaa
      361 gacttagcaa aaacatttaa ggtagaattg ccacgtgtca atttttatga aggcttgaaa
      421 aatggaaact tggcttcttc tattattcat ttgactgata atttagactt gatccctggc
      481 acgtttgatt tgatgttact gccaaaatta actcgctcat ggacgtttga aaacgaaagt
      541 agattgcttg ctactctttt agcaccttta aaaagtgact atgatctcat tattattgat
      601 actgtaccaa cgccaagcgt ttatacaaat aatgcaatcg tggcaagtga ttacgttatg
      661 atccctttac aagcagaaga agaaagtaca aacaacattc aaaactatat ttcctatttg
      721 attgatttac aagaacagtt taaccctgga ctagatatga tcggttttgt tccttattta
      781 gttgatacgg acagcgcaac gataaaatca aacctggaag aactgtacaa agaacataaa
      841 gaggataatt tggttttccg aaatattatc aagcgaagta ataaagtaag tacctggtct
      901 aaaaacggca ttacagaaca caaaggctat gacaaaaaag ttttatctat gtatgagaac
      961 gtattttttg aaatgcttga gcgaatcatt caattagaaa acgaaaaaga atagaatcac
     1021 aaatcacaag tgattaatca caaatcactt gtgatttgtg attgttgatg ataaaataag
     1081 aataagaaga aatagaaaga agtgagtgat tgtgggaaat ttaggcgcac aaaaagcaaa
     1141 acgaaatgat acaccaatca gtgcaaaaaa agatataatg ggagataaga cggttcgtgt
     1201 tcgtgctgac ttgcaccata tcataaaaat cgaaacagca aagaatggcg gaaacgtaaa
     1261 agaagttatg gatcaagcct tagaagaata tattcggaaa tatttacctg ataaacttta
     1321 aaaaggagtg aaaatgaaat ggcagttacg tatgaaaaaa cttttgaaat agagatcatt
     1381 aacgaattat cggcaagcgt ttataatcga gtattaaact atgttttgaa tcatgaatta
     1441 aataaaaatg actctcaatt attggaagtc aatttattaa accaattaaa gcttgcaaaa
     1501 cgtgtaaatc tttttgatta ttctttagaa gaattacaag ccgttcatga gtattggcgg
     1561 tcaatgaatc gttactcaaa acaagttttg aataaagaga aagtggctta atatggcaaa
     1621 tatagtcaat tttactgaca aacaatttga gaatcgctta aatgataatt tagaagaatt
     1681 gattcaagga aaaaaagcgg ttgaatcgcc aaccgctttt ttacttggtg ggcaaccagg
     1741 gtcagggaaa accagtttgc gatcagcaat ttttgaagaa acacaaggga atgttattgt
     1801 cattgataat gataccttta aacaacagca ccctaatttt gatgaactag tgaaacttta
     1861 tgaaaaagac gtagtaaaac acgttacccc ctattctaat cgcatgacag aagcgatcat
     1921 aagccgtttg agcgatcaag ggtataattt ggtgatcgaa ggtacaggac gaacaacaga
     1981 cgttcctatt caaaccgcaa caatgcttca agccaaaggt tatgaaacaa aaatgtatgt
     2041 catggcagta cctaaaatca actcatattt aggaacaatt gaacgatatg aaaccatgta
     2101 tgcagatgat ccaatgacag ctagggcaac accaaaacaa gcgcatgata ttgttgtcaa
     2161 aaacttaccg accaatttag aaacccttca taaaacgggc ttatttagcg atataaggct
     2221 ttacaataga gaaggagtga aactctattc aagcttagaa acgccttcca ttagtgcgaa
     2281 agagacctta gaaagagaat taaatcgtaa agtatcaggg aaagaaattc aaccgacttt
     2341 ggagagaata gagcaaaaaa tggttcaaaa tcaacaccaa gaaacccctg aatttaaagc
     2401 aattcaacaa aaattggaaa gcttgcagcc acctatacca ccaataccca aaacacctaa
     2461 acttccagga ctttaaacct taaaaaagga aaagagtagt taccaaaaaa cggtaactac
     2521 tcttttttta taaaaacctt tcctcatgtt tgaaaagctg atcgagaaat aaagcacaca
     2581 acggtattct ttcttttttc agttggtaca ttttgcagtc tgtaacgtgt catttactgt
     2641 ttgttacctt aacatatcca gtcgaaaaca caagggtata taaacgagca agctcgccct
     2701 tgtgttttct ttgtgtctat gttgcgttct cgtcacagca aacgacacga acacactggc
     2761 gaaaatgaac caactgaaaa aagaaaggag catacactgt aatttatttc tagcttttaa
     2821 aacatgagga aaacagcttc acttcctcaa acgcctaaca aaaatggttg tcaaaaaact
     2881 aaaaatcaaa aaaaagaaaa gaggaaaaga aaatggaaaa aacaaaaaaa ttacaattag
     2941 aagattttac agaaaatgag ttttttggaa cacaagaaca gcaatatcta aaagctcaag
     3001 taagagaaga gctaaaagag caaggcttta tcatagatag cagttttgag ggcgatttta
     3061 aaacatggat aggtgtatac gcaagaccaa aagataaacc gacctactta gaccctcaaa
     3121 acgataaaga agcagaagaa caagagcaat attctattaa cggctttaaa caagatttta
     3181 gcgaatggtt tgagtgggaa ataaaaaatt tgaaaattaa agaaatgtaa aaaaaagcca
     3241 aaaatcaaaa agaaaaggaa tgatgaaaat gaaatacatt aaaaacgttg aaacattaga
     3301 agaattgaaa aaagcctaca aaaagttagc tttgaaattg caccccgatt gtggtggtag
     3361 caatgaagaa atggcgcaac taaacaatga atatgatgaa ttgtttgtca agctaaaaaa
     3421 cactcataag aacaaagacg gcgaaaccta tacaaaagaa acgactgaaa cgcccgaaca
     3481 atttaaggac attataaatc aacttttcaa tctgaaaatg gacggtgtat caattgaaat
     3541 cgtgggaact tttatatggt taacaggcaa cacaaaacct tataaggacg acataaaagc
     3601 cctagaattt cgttattcac caaaaaaata cgcatggtat aaagcaccaa gcgattataa
     3661 aaaacgtagt cgaaaaaatt atgatatgga cacaataagg ggaatgtatg gaagtcaaaa
     3721 ggtgaaggaa gataaagaag aaaaaaaata cttacaagcc aattaaggct tgtaagtttg
     3781 tcagaaagga agttttaaag tggatattaa aataaaaaaa ataaagggta ttcggatttt
     3841 atggtggaaa agggcctata agttactctt ttccaatttc ttaataagtg tggaaaaatc
     3901 tacaccatag ttgcctgttt tgtctcggtc tgttatttga tacgaattga aactatcgta
     3961 taacatagct ttgctgaatg cacttgaatt aaatcgtggc ttcctctttt tatggagctt
     4021 ttcattaaaa attattttag ctcgtaaaaa cggaactctt ttagaagctt tgagagcgga
     4081 actacctgca tttgaacaaa ccattgtccc tgaatttaaa ggggctgtta gagctgtttt
     4141 gaaaaagatt catcgtcctt ctataggggt taaaatgggt gaaatagcta attatagttc
     4201 cacatcaagt ccaatgggac aactgaagaa aatgtttggg taacgaaaca cacagaatga
     4261 gcaattttaa tattaaaatt gaagagttac catctctaga gaaaagtttc cgccaaagta
     4321 ttgacacata caaatcacca ctattacttg acaaatggaa tcacctagta taaaatacta
     4381 actaccggta gttagtatta aggatggtga attatgaaaa caaaagattt aattattgaa
     4441 gaatttataa aatcctttgg tgaaaatgga tttgaaggaa cttctgttga ctatctagca
     4501 aagcaagttg gcataaagaa aggttctatt tatacccact atagtggaaa aaatgaaata
     4561 tttactattg cctgtgaaaa aatactagat aaatgtatcg ttgctataaa acaattgctt
     4621 gaagtagaga gggataaacc attagatgaa caacttttta ttttgcttaa aactgtctgt
     4681 ctagaaagtg attttttaac cgctgatgag atagctttca gcaagcgcgt tgcaatttta
     4741 tctagcagtg aattgttgtc gcttgtagat aaattattag caaaatatga taattttatt
     4801 gacgacacag tatcacgaat ttttattgat tgtgctaaac aaaaaatgtt ggcagaagaa
     4861 gagataacgt ctgccataag tgtatatcgt atgttgttgg aaaacttata tattgattca
     4921 ttagcaaatc aaaattgtaa tgaaaaattg aatcatttat ggagatattt ttggaaaggt
     4981 gtttgcagtt aaaaattaaa taaacttgat tggaggttta attttggaaa ttattaagta
     5041 tattggagca gcattttcaa cttggttcat aggttttttt ccttattttg aaatttatat
     5101 tgcaatacct gcaggttttg cagccgggct aaattggttt gacgcttttt tatgggcttc
     5161 actaggaaat tggatggtta ttccgtttgt ggatatatgc tatgaatggt taatgaaatt
     5221 taatttcatg aaaaaaatca tggaaaaaag tctaaatgga aaatgggaga atcgcataga
     5281 aaagcatggt gcatgggtta tacttttgtt aactccttta gcaggtgttt ggacaatagg
     5341 tgttattgct aaagcactaa agtttaatcg agcaaaactt tggatatata gtgcaactag
     5401 tgttgggatt actggattaa ttattacgat attaattata aatggaatta
//
LOCUS       DAXLPQ010000099         5341 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.102, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000099 DAXLPQ010000000
VERSION     DAXLPQ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.102"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(62..286)
                     /locus_tag="ACF3UO_002647"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACF3UO_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACF3UO_002648"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACF3UO_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="ACF3UO_002649"
     CDS             2092..3132
                     /locus_tag="ACF3UO_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFD3658583.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /gene="traE"
                     /locus_tag="ACF3UO_002650"
     CDS             3956..4288
                     /gene="traE"
                     /locus_tag="ACF3UO_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFD3658584.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="ACF3UO_002651"
     CDS             4907..5248
                     /locus_tag="ACF3UO_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFD3658585.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1770 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattaa
     4861 tataaagcat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 t
//
LOCUS       DAXLPQ010000100         5314 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.103, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000100 DAXLPQ010000000
VERSION     DAXLPQ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.103"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            263..643
                     /locus_tag="ACF3UO_002652"
     CDS             263..643
                     /locus_tag="ACF3UO_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFD3658586.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            625..1539
                     /locus_tag="ACF3UO_002653"
     CDS             625..1539
                     /locus_tag="ACF3UO_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFD3658587.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            1784..2473
                     /locus_tag="ACF3UO_002654"
     CDS             1784..2473
                     /locus_tag="ACF3UO_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658588.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(2594..2680)
                     /locus_tag="ACF3UO_002655"
     CDS             complement(2594..2680)
                     /locus_tag="ACF3UO_002655"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFD3658589.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            3356..4306
                     /locus_tag="ACF3UO_002656"
     CDS             3356..4306
                     /locus_tag="ACF3UO_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFD3658590.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            4327..4860
                     /locus_tag="ACF3UO_002657"
     CDS             4327..4860
                     /locus_tag="ACF3UO_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3658591.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            4876..5046
                     /locus_tag="ACF3UO_002658"
     CDS             4876..5046
                     /locus_tag="ACF3UO_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658592.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
BASE COUNT         1983 a          970 c          993 g         1368 t
ORIGIN      
        1 aaggtgaaac aagcgaaact ttacaaaaag tggctagcat ttgctagtct tttttgtatt
       61 gtggagagtg gggggggagg gggattcaag ggggagcttg cgcccctttg acaagcggtt
      121 atttgcacca aatacgtagg tatttggcta gcaaatatag agcttgccaa acccttttag
      181 tgagctttac tcattgtacc tttttaggta caatggtatt gcgaacgata cgtccgtagg
      241 acgtactgaa agggtgggac ttatgagcga acaacatcaa aatttggcta gcgatcattc
      301 taaaaaatat acctatcgat ccgagccaaa acaaatcagt tttcgagtga gcgaatccga
      361 atttgcaaag ctgaagcagt cagctgaagc tttgcaaatg agtgtgccgg ctttcgtgaa
      421 agccaaggca caaaacgcgc gtctggtgac accgaaagtg gcgccagaca ttgcccaggc
      481 aatcgcgcgc gatttagcca aagctggagg gaatatcaat caaattgcca agtggtgcaa
      541 cacacaccaa cacgacgttg ctcctgatga tgctcaacgt ttatccgaaa acctaaaaat
      601 catgcaaaag gagctacaaa agatatggca acagttaaag taagtcgaac cacttcatgt
      661 agccgagcaa tcaattacgc agaaccacga gcaaccgtca aaacaggaat aaactgtgac
      721 attgattatg ccaaaagtga aatgaaacaa atacgcacgc tttatggaaa agacgatcgt
      781 gtacaagcac acttattgat ccagtctttt cgaccaggag aaattaccgc tgaaaaagcc
      841 aatcaactag gggcagagta tgcgaaaaaa atagccccta accaccaaat cgcgatttac
      901 acacatacag acaaagacca tattcataat cacattgtca ttaactccgt caatctggaa
      961 actgggaaaa aatttcaagc ccatgggcaa gcatttttaa acaaatgtta tgacctaaat
     1021 gacgagattt gtcttgaaca tgacttaaca atcacggaac gaggaaagaa aaccgaaaaa
     1081 cgaaccatgt ctgaaattaa attaaaagaa aaaaatgaac cggtttggaa agacgaaatt
     1141 cggtttgcga ttgatcaaac aatgaaaaac aaaaaaactc gaacgtatac ccaattttgt
     1201 gattcactta aaacattcgg cattcattgc ttgaatcgcg gaaaaaattt tacttacgaa
     1261 ttggtccaca aaaagaaaaa agtacgatcc aacaaactag gaaaggatta cgaaaaggag
     1321 acaattttac atgagctgga cagacgagaa cgagcctaca atcaacaacg aaccaacgag
     1381 ctacgaagag ctcgagctag cattcgcgaa actgcagaag aagtacgaag agaacaacga
     1441 acttttacgc ctgaacaatc ggaaattaga ccgactcgaa gaaaccatga acaacacgtt
     1501 gaacgaggaa cagaccacca acaagaatta tcgctctaaa acgttaaaag acatcgaaaa
     1561 cgaaataaag agacaacgtg cctttcttgc gccttatacc caagaaagga tacaaactac
     1621 gatggattca caagtcaaaa aactccacca agcgctatta gaccagcgaa accaagaaca
     1681 aaaaaaggct ttaattcaac gatcgatgga tattcttgcc cccttatgtt gcttagtact
     1741 aacattatta gccttttggt tggtatgggg agaataaaca gacatggcat tctatttacc
     1801 ctatctactc atttctgcca gtattttagg aattatttgg cttagctata aggcttatca
     1861 aacaagatat tcattaaaag gctctaaaat tcgatttaag cgatttttat tggtcggggt
     1921 tatatttgcc ttatcaatcg ttttaagtgg tttattcggc gttttagagg gtaataaacg
     1981 tgtttcaaga agcattttat taggggatat cactcaaaag tatgaagcag catgtgataa
     2041 aaagaaaaaa gagcaagcat tagcacaaaa aatggaggaa tttaccgctt gttatgagga
     2101 catgaacaat atttttgtgg atcaagagaa acgtttaaca gataaaaaca tgaaaaaact
     2161 cactcgtttt tatcaaaact taccagaaaa acagcaaaaa gaggtacaag aaaaatatga
     2221 gcaagtaaaa aaagacgtgc aatattttaa agatacgcag acagaagaag cttgttgtaa
     2281 cttatttagc gatacaatcc ctttttcaac cagtgaacaa gaacgaaaag aacggcaaca
     2341 atcggtcaca tacgaacgtt atgaaacact gcttcagcaa gcaacaaaca tacaaaatcc
     2401 aacgaaaaaa gaaacggcat taaattatct agaaagtgtc aaggaatggt tggatcagca
     2461 acaacaaaat tgaatttgat tagcaatcat gttaaactga acctgcaaat gatcaaacat
     2521 tagatacacg aaagccccag agaggtcgga ttctctgggg ctttttttca ggttgatgtc
     2581 gcctttattg attttacttc ttgtttcggt tattcaacca ataactgaat aaagagacac
     2641 aaacttctac aagaaggggg caaatgaacc gttcaaacat tagatacacc tccttccagt
     2701 cgcaagactg tcggataggc gacaagttat tataccttac aaaataaaat ctgtgtggtg
     2761 tttttaagta tcccttattt tcgggttgtt agggcttgcc ctgaccgcct gtaaggcgct
     2821 ttaagaacaa gataaggttt tttacccaag actgtcttaa aacgacttag acgagctatc
     2881 agaggcttcc cccacctccg ttactgactt gtttttagca aaggagcctt taggcgactg
     2941 cgcagtacaa tgtgagagca tagcgatcac acttttttag cgaccgtagg gagcaaggtt
     3001 ttgaattggc agttttgaaa aatgcgcgaa cctgttggta gaaaaaagaa gtggttttta
     3061 ggcgggaaat tttgtcaccc tcttttataa tctcttttta aacctttttt taaacctctt
     3121 taccgtcggc tgtgtcctta ctccttcaat ggatacagcg ttttataaac tacattttgt
     3181 ctgcttttaa actacatttt gtctgctttt aaactacatt ttgtctgctt ttaaactaca
     3241 ttttgtctgc ttttaaactc tttttttgca ctcacgtatg ttataatatg cattatcaca
     3301 gacaaaacgt tgtttataac gtctgtatcc attgaaggag taaggaggaa tatctttggc
     3361 aaatgaaatc gtgaaatacc atcatgaatt aaataccatt ccgttgcgga aatttacacc
     3421 agttgaaatg aatctatttt tctctattgt gtctagaatg cgcgaaaaag gcgataaaac
     3481 agtccgtctt acttttgacc aactaaaaga tttaagtaat tataaagcaa ctgctaataa
     3541 tcgtttcatt aatgatttag aaatgactta tgataaatta atggatttac gttttggtaa
     3601 aagaagtgct aatgggctcg atatagatag attcgttatg tttagtgagt ttaaaatacg
     3661 tggaactgct aaagatccat atgtagacat acaagtttac gaaaaagctt tacctttact
     3721 aaacaattta gatgagtggg ttcgctattc actccaacaa tttaacgaat tacaaagtag
     3781 ctatgcaaag actatgtttc gattactaaa acaatatcga actaaaggtt ttgcttattt
     3841 ttctaaagag gattttcatg aactattaga tattccaaaa agttactgga acaaccaagc
     3901 aaacgttgat aatcgtgtta taaagcctat acgacaggaa ttaaccgcaa tcttcaaagg
     3961 attatcaatc aaaaagaaat acggaaaagg gcgaggaaaa cctgtcgttg gctatcaatt
     4021 tacgtttaaa ccagaaatca aaaaagcaga tgattttaat aaacatgcac caaccaaaga
     4081 agaacaaaat aaagcattgg ctttagctga taaacaaaaa gaatacgaag aacctgctac
     4141 aacaattaac gaaaaaatca aacagaagaa acgagaactt gaactcctcc aacaaatcaa
     4201 acaactagaa aaagagaaag aagctcttga aaaacaaaca gagtccgcac tttcgaaaaa
     4261 agagaaaaaa agtttattat ctgatttaga taatttattc cagtagcaac ctaggaggca
     4321 accagtatgc aaccacaaga aacctttaca ataaaggaat tgtcagaact ttttaagatg
     4381 agtaggcaag caatatcgaa acatatccaa aaattagatt cttccatgat agctaaaaat
     4441 gagcgtggtt ataaggttgt attgcgttct ggagtattgc aacttgctcg caacttaggc
     4501 aaccaaatgt tgctagatag gttgcacgag tacgaacaag acaacgataa aaatgttaat
     4561 ataccaagca aaaacgtggt tacaaacaag ttgctagatc agttgcgtga agaaaatgaa
     4621 tttttacgag aacaacttgc cctcagagag caaaataatt ctcatataca aaaactactc
     4681 gaccagcaac aacaactcac cctacaagcc aacaaacaaa tcgaaaaact gcaagaaaaa
     4741 ctacagttga cttatacaga agaagctcca gagaatgact caacgactct ttctgaagca
     4801 acagaaacaa tagacaaaca aattgatact gaaaaaaaat ggtggcaact ttggaaataa
     4861 ctggagggaa cattcatgac aagaaaaaat cttctattcg gttctatttt actaggaatt
     4921 ctaggattca gtccgatgtt attgtcagtg atcaataaag ggaataaaca tggtgaattg
     4981 aaattgaatc caaattatta caacagtcct aacgaagaat tgtttgtaaa agaaacagat
     5041 aaataataaa aaagactgct ctttcgagca gccagttaaa aaataatgag tgtttattct
     5101 tgaaaaagca acgcgcttat gaagcgctac caaaaattta tcatatttta ttaaaaataa
     5161 caacccagta aaaaatgact ggtaaaaatt cacaaagaaa cggaaagaag caaccgcaga
     5221 aaatcaagct taaaaagagc ttttgaccta gaccaatcga aaatcacaaa gtgagcctct
     5281 gtatcggttg atacaagggc tacttggcat agtg
//
LOCUS       DAXLPQ010000101         5050 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.104, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000101 DAXLPQ010000000
VERSION     DAXLPQ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.104"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            132..725
                     /locus_tag="ACF3UO_002659"
     CDS             132..725
                     /locus_tag="ACF3UO_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658593.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            747..2441
                     /locus_tag="ACF3UO_002660"
     CDS             747..2441
                     /locus_tag="ACF3UO_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFD3658594.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            3129..5006
                     /gene="ltrA"
                     /locus_tag="ACF3UO_002661"
     CDS             3129..5006
                     /gene="ltrA"
                     /locus_tag="ACF3UO_002661"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3658595.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
BASE COUNT         1868 a          820 c         1095 g         1267 t
ORIGIN      
        1 gaccctataa taaccctggt caacgccaaa tttttgcgat tatcgaatct attttcttta
       61 cggataagaa ccactatcat gcgttagatc ctaaccgaaa ttatcatggt acgtataagg
      121 aggatgaata aatgcgagtc aaaggacaaa attcagttga taagaaatcc attttgcagt
      181 ttggaaaacc agaagagcgc tctatcttgg acttatttcc atataaatcc tgtacagaag
      241 agggagtctt aattactaga gaagatcatt ttcagcgtta ttatcgtgtc gtttccactg
      301 acgtggaggg attaaatgaa caagagaaac tagaacgaat gaatcagttg accaccgtca
      361 tgcgtacgta tgtgccaaca attaagttag ttagtttgac cacagagacg gatctaacgg
      421 aacaaatcgt gcaaaagcgg cagttattag ataaaaatcg tatggaacag tcactaggaa
      481 gaaatctaca gcgattaaga aaatatgaaa agaaattagt agaggagatc caggaattaa
      541 aacgggcaga acaagaacgt cctgacttaa gcttcttttt cgttattgaa ggaaagacaa
      601 tcaaggattt acaaactaga aatcgtcagt taatgcgatc tagtggcatt ttagggttaa
      661 aaccactcta caaaaaagaa ttgattaaga ttctttatcg aatgaacaac atgaatgacg
      721 aataaaaaag atggaggaaa tgattcatgc tagatgtgat aaaaacagct ttttcaacgc
      781 aaagtaatca aaaggtgatt gatccattaa aacaacttgg taatcgtgaa atagagattt
      841 taaaatcaaa aggttatgat ttagatttct taaaacaagt gatgccacaa ggtgggttga
      901 attttgatga agaatatgtg acctatggaa atggttattc acgatgtgtg acagtttatc
      961 attacacaaa aaatcctact cttttttggt tggccaatct catgaacaat cctcatacag
     1021 tggccacact agatgttagc acagatgaaa agcaaaaagt gattgatcaa atcaaccgcg
     1081 cattagatga attaaatgat cgatcagata atgaacgaaa agcgactgac cgaaataaaa
     1141 gtgcggaaga atacctggaa ctagcggaat atgcccgaaa attgacttct aatggggaaa
     1201 tttctaaaca agtcaaagtg agagtacatg tttacggaaa tacgatccaa gaagtggatg
     1261 aacgggcgca ggaactgatc gaaaatctaa aagggatgga ttatcgtgcg gtgacttatc
     1321 tgcataaaac caaacgagat tggcaatcga tgtttaccat gttcgatgaa caagctgaat
     1381 ggtttggaaa tatcaaaggg caatcacttc catcgttaaa cattggcgga ggattcccgt
     1441 tccaccacca aacgctaaaa gatccaggag gcacacaata tggggaaacc atgacaggcg
     1501 gcccatttgt ctggaatgcc acgtataaaa atagtgtacg tttatctacc aataccttgc
     1561 ttctaggaat gatgggagct ggtaaatcga ccgttcttaa aatgatcgcg gaagcccatt
     1621 tagctgcagg agactttatt tggggctttg aaaagggaaa agactttatt cctttcttaa
     1681 aggaatataa cggtattatg gtgcgtttag acggatctga cggaatgatc aatcctttag
     1741 agatatttgc cacacggacg tatgatgaag catccagttt atatgacgat ggatcagtca
     1801 aagatttgaa gatcaatgaa gcagcgtcct atcaaacaca cttagacaaa gtggtctatc
     1861 aggtacagtt agtgagtcct cagctaaaag gaacgatgaa agcagaattt aagacctact
     1921 taaatcgttt ttatgaagag tatggaacag taccacgcgg ctttacttcc tcaaattcgc
     1981 gttcaaatac tgatacgcaa gtcacaggga aagatccaga agcttatccg acgttcaaag
     2041 aatttttagc ctttttagga caactggaac taccaggggc ttcccaagag aaaaagaatc
     2101 ggaaagaaga aatggagtct atcgtggaat ccttatgtga gacttatggc atgatttttg
     2161 atggtcatag tacgattcga caccttgacc aacaacagtt ggtctttttt gacattgact
     2221 ctattacagg cctagatcga ggggtacaac aatgtcagat gtacatggcc atgacgttga
     2281 tttggaatca ggcattgatt caaggacgaa gacaacgacg cttaattaaa gaaaaacaaa
     2341 tggaagaaca agacttcaaa cgcttcttgg cgatgattga tgagtgccat aatggtgcga
     2401 cctgttctgc agtgaaaagc tgtgggttgc aagtagtcta aaaactattg taataactct
     2461 tataacgaga agtcaaatga gtgggtaacg ccacaaaggg cttccactga tactccgaca
     2521 tgcaacaagt agtttatgca gaccaacgtt gtgtgaagct cggtgaagtc ggctgaagga
     2581 taccgtaagg taaaagaaat agtgaatacc acgaaagttc tctagaggta aagggtgtat
     2641 ccgataagtc gggtgtccaa aaaaacttaa tatggtgagt atgtacaaac gtactgacga
     2701 actagcgaat gtactgtccg aaaggcatag ctcctagaaa tgggagagac agtgagcaaa
     2761 aaatcactca ttgtgctaac ttgtggttga gtaaaagtcg ttgttatgaa agaccatgct
     2821 gcgttacagg cgtaggagaa gttagggggc aaaagctagc atctaagtta aggcatgtgg
     2881 atagatataa gggaacaggg gaagccatca acatggagag tgcatactcg atgaagtggt
     2941 agtaagaaat atgtgaatga caaataactt actttagtga tggtgaaagt agagtcacga
     3001 ctgatgaagg ttctgtaatg gaactggagg aacaggctcg attcgtctgt aaaagtcatg
     3061 aaacccgttc aaccatggga ttctcgtatg actaaaaagg tcacgagcca attggagcgt
     3121 gataaaccat gacaaaagaa acaagtccaa aagataggaa gttgcggcat gcagaatatt
     3181 atggcatgac ggaaatcttc gataagatat actccaaaag tttgaaggga gataatttca
     3241 agaatctaat gcagattatc atttctgata acaacattgt cctagcatat cgtaatatca
     3301 agagaaatca cggtagtgtg acaagaggag aagatggagt aacgattaaa gatattgaaa
     3361 atctcaaccg taatgaattc gtagaaattg ttaggaagcg attcgcacat tataaccctc
     3421 ggaaagtaag gcgtgtagaa attcctaaat ataatggtaa attaagaccg ttgggtattc
     3481 catcaatatg ggatagaatc gcgcagcaat gcatcttaca agtattagaa ccaatatgtg
     3541 aagcaaaatt caataatcac agctatggtt tccgcccaaa tagatcagca gaacacgcaa
     3601 tagcagattg tatggcccga atgaatcaaa gtcacatgga atatgtggta gatgtagata
     3661 tcaaaggttt cttcgacgaa gtcaatcata ctaaactcat gagacaaatc tggtctatgg
     3721 gtatacgaga caaacagctt ctcttaatca ttaggaaaat gttaagagca cccgtagtac
     3781 ttccaaatgg gaagttgata tacccaacaa aaggaacacc acaaggcgga atacttagcc
     3841 cattacttgc gaacatcaat ctcaacgaat ttgactggtg gatagcaaat cagtgggagg
     3901 aaaaagatgc caaagagcta aaacatcatt ttaggaaaaa tggagcttgg gataaaggta
     3961 atatctatca caagctcaga aagagtacaa ctctaaaaga aatataccta gtgagatacg
     4021 cagatgattt taaaattttc tgtagaaatt ataatgaagc gaaaaaagtt ttctatgcaa
     4081 ctaaaatgtg gttacaggag cgtctaaagt taccaatatc tgaagaaaag tcaaaaatca
     4141 caaatctttc aaaagaagaa agtgaatttt taggctttac gatgaaatta gtgaccaaag
     4201 gtaacaaaaa ggttgttaat acgcatatag gtacaaaagc acaaagcatg attaaagtga
     4261 aactaaaaaa acaaatcaaa cgaattcaaa aaagtcctaa tagcaaagat acctttatct
     4321 atattggagt ctataacagt atggttattg ggattcataa ttacttcaaa attgcgactc
     4381 attgtagtgt agcaatgcga aaaattgcaa gagaactcag accaagtttt gaaatacgac
     4441 tacgagaaca aggaatctca aaagaaggac aatacggaaa gtacgaagga tacaagcctt
     4501 acctacggtc aggacaaata cgatatataa gagggtttcc aatattacca gtagggtata
     4561 ttcaacacag acatccgatg tgtaaaaaaa gaaatattaa taaatacacc gaagaaggta
     4621 gggaagccat tcataagaag caacaaaccg tagaagaatg gaagatatcg tggttgtgta
     4681 gcaatccagt gcttagtaag agagcaacga ttgaatttgc ggacaatcga atttcaaaat
     4741 tcatcgctca aaagggaaga tgtgcagtaa caggtgagga gcttatctta tctgaaatgc
     4801 attgtcatca tattatccct tatcatgaaa gcaaaagtga tagctatgaa aacctagtga
     4861 ttgttactga ggaggttcat cgggtaatac acgctacaca aagtgaaacg attgaggaac
     4921 ttctaaaata tctaaaatta aatccaaaac aaaaagaaaa actcaatgag ttgagattaa
     4981 aagttggtaa cgaagaaata tcttaataaa tatttgtagg acgggaaaac agaatgtctt
     5041 ttatagacga
//
LOCUS       DAXLPQ010000102         5002 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.105, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000102 DAXLPQ010000000
VERSION     DAXLPQ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.105"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..681
                     /locus_tag="ACF3UO_002662"
     CDS             <1..681
                     /locus_tag="ACF3UO_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658596.1"
                     /translation="VVVYGVAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQ
                     FIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMY
                     LFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHT
                     SIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKP
                     YVLGKVVI"
     gene            725..994
                     /locus_tag="ACF3UO_002663"
     CDS             725..994
                     /locus_tag="ACF3UO_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658597.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1226..1522
                     /locus_tag="ACF3UO_002664"
     CDS             1226..1522
                     /locus_tag="ACF3UO_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658598.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1524..1946
                     /locus_tag="ACF3UO_002665"
     CDS             1524..1946
                     /locus_tag="ACF3UO_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658599.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1965..3557
                     /gene="mobP2"
                     /locus_tag="ACF3UO_002666"
     CDS             1965..3557
                     /gene="mobP2"
                     /locus_tag="ACF3UO_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFD3658600.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            3578..3898
                     /locus_tag="ACF3UO_002667"
                     /pseudo
     CDS             3578..3898
                     /locus_tag="ACF3UO_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4059..>5002)
                     /locus_tag="ACF3UO_002668"
     CDS             complement(4059..>5002)
                     /locus_tag="ACF3UO_002668"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3658601.1"
                     /translation="GPHAGGKHYPKKGFNHIRSKVKMSDVFEFIQSNVHDHDVKQMCT
                     VLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHKILVGRGETL
                     SLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSINQKWVTDITY
                     IHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTPSENLIIHSD
                     LGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYPSKAYENFEA
                     AYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT         1803 a          771 c         1012 g         1416 t
ORIGIN      
        1 gtggtggtct atggggtggc ctattacttg ttaagtgagc caaaacagat cgcggcgtca
       61 aatattttca cggcagtaat gacattaatg tgtgtcatgt gcttttctat ttttagttac
      121 ttactcgtcc aatttatcag gcaaaattta acaatgagta aacttttcaa aagtttattg
      181 gacttactta tcttaggcag tatgttaacg actctaacag atcggttcga acaatctgaa
      241 aaaacggtag aggggataaa gaacttctta acgacgattg atcaatttat aaatggatat
      301 atgtatttgt ttgaagtagg ctttattctc actttgtttg gttgtgtatt tataaaactc
      361 attaaaagat caatcgaaaa agaaatggtt attgatctaa ttccgacgct gagcggctat
      421 gagtattacg ttgattttgg aaagtatgag gagttgatcc atacggatat cgttcacacg
      481 agtatccatg aagtaaccgt taagggcatc agatctactt taaaagatgg acaggagacg
      541 aaaacaatcg accgaagaaa agaggtctac aatttttata aagttgaagc aagtctacga
      601 tatggcattg ggaaattgag gttagatggg agtaatattc aacaaaacaa accatatgtt
      661 ttaggaaaag tggtgattta gaacttccta tgaaagatga ataaataagg agaatctttt
      721 gaaaatgatt cttctttaca gaattgtgct tatagttggc acggagttaa aaatcttaaa
      781 gaaggagcag ttattcaaag tgaaagaaca tcataatcag ttactatgta ttaaaacggg
      841 tacgatgaac attcaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt
      901 gtcgattcga gagcaacata agcaagaaaa attaatggct acttatagcc aattgattga
      961 tgagtgggaa caattcaagg aatctaaaac ataaaattcc atttaaacac cttatttttt
     1021 aaagagcata aggaaacgtg accccacttt taaaaaaagt ggttggatag gctgtgccta
     1081 tcacgtttct gaaaaaaata aatgacccca aaataccaat atataggata gtacaaggat
     1141 agcaaaggat agtaaaagga tagaggtagg atagcgaaaa ggataggatc cttttcacta
     1201 tcctatatta tattggagga tatttatgaa tgttaaaatt agagatttag atccaaaatt
     1261 catttctgaa attgatcgaa gatgcgttga actaagtaat cgtacaggaa ataaatggag
     1321 tcgtaatgat tatttaaagc tactcgttga aaatgatttt gatcgtcctt tgatggaata
     1381 caaacaagaa aagtttgacc agttattaga aaagttttca gaaattcaaa gttataacac
     1441 aaagatatta gaagaatatg ttagccaaaa taatcgtatt atagaaatct tgattgagca
     1501 aaatagagga agtgaacttt gatatggcaa aggttataga caaacacatt tactttcacc
     1561 aaacacatat cgatgtattg gatgaaacta tttctactca tgcagaggtt aaaaactata
     1621 gtgaagctgt tcgcttttta tgtatgaact atgatccaga agtggagaaa aaagtaaatt
     1681 ccaatcaagc aaagttgaat ggaatgagta aagaaatttc tattttaacc gaaatggttt
     1741 cagaatttgc ggatcttcat ttgaaagata caggaatatt aattggtaaa aattcaactg
     1801 tttatcaaga agcaaaagaa cgagtggaag gaaaaattaa atccaatcaa acaaaaaaat
     1861 attcccctca gttgaagaaa cctgtgaatg aatctgttca tgccagagta gatccatttg
     1921 atccaacgaa gattctaaaa agataaaaat gaaggaggat aataatgact caatcgcctt
     1981 cagttattct cacttgtcaa tttactttgc cgaataaaaa gtcattttct acttatattg
     2041 actatattac aagggaacag gctcttgaag aaaaggaacg acgtacgccc gaagaagaac
     2101 aggaacttca acgaatcaag aatgctttag aggagtttta tattcctgaa ggagaaactt
     2161 tttcggagag taagacgggt aaagaattca gtgaaacgtc gaatgaagct caatcgttga
     2221 tggaacatgg aatcaatttt gacaagttag aggaacaaga ttttaccaat tatctttctt
     2281 atatgacacg tcactatgcg ttagaacaaa agaaagaact gacgcaaagt gaacaaaaag
     2341 aataccaacg cttgaaccaa gcaatgaaaa aatatcaaac agaaccccat aaaaaagctt
     2401 caggaaatct tcctggagtt ttttctatag cttcagacga agtgaaagga agtgatctga
     2461 aggagattaa gcaaatcttc caaagaggac aacaaaaagg ctcaatcatt tatcaagatg
     2521 ttgtttctca tgataattcg tatcttgaaa aaataggatt gtacgatccc aaaacagata
     2581 ctttagatga agaagggtta aaagcagctg gaagaaaaat gatggagaca ttattcgaga
     2641 aagaacaatt gaatgaaaca ggttactgga tggcaacgat tcaccgtaac actaaacata
     2701 tccatattca ttttgcagtt gttgaaaaag aaaatacgcg taaaccttac acggaggttg
     2761 aaaatggtgt gagttatatc gtaccgaaag gtaagagaag acaagcaaca ttagacgcaa
     2821 tgaagaccaa ttatgtacat gagttagaac gtttttctta tgaaaaggat cgaatgattg
     2881 gtatggagaa acgaaattta ttgacgcgga aaagtgattt gcgtaacacc ttaacaaaag
     2941 tggtaaaaga gccagcgcgt tacgatcgac acgcgatgaa cttattaaat gaagtatata
     3001 aaaccctacc tgacaaacgt tcggaatgga attacgggga tgaaaaacga accaaacttt
     3061 caccatacac aagagagaaa ctcgatgagt taaccaaata tgttttaaca aaagaacctg
     3121 aatatcaaga atatatacag atttcaaaag cattgaaaga agaagcaaaa agtctttatg
     3181 gggaaagcaa gagagaatca aaggatgcag agaaaaatgc tctctttgat ttaaaaaagc
     3241 gcacaggaaa tgccatccta acagagctga agagacagga tagtcaaata aaaccattaa
     3301 tagaaagtgt tgatcagatg caatctattt acaatgaacg atcctttcga acgcttaaac
     3361 aattgccaac gaatgaatac aaatatagtt acgaagaatt catgaagcgc aggaaacaat
     3421 tccaacaaag agttgtcacg cagcggagtt tgcgtcaatt aaatcgaacg attaatgccc
     3481 atgaagaaaa ataccacgca agtaaagcat acgaagagca acaacgaaga attcaaatgg
     3541 aacaagaaag acagtaaaga cagtaggagg aatagcaatg aaacaatatt tagatcaatg
     3601 gaaagttata gaaggatcat taagagaaga acgaatcgaa caacttcctg attgtttaga
     3661 aaaagagcat ttgttccaga taagagaaat gttgagaaac gaacagtttg atccaaatca
     3721 atttttagtc gttgagtacc cagctactgg tgtgtattgt tgtaatcatg tgaatggtga
     3781 aaaatatttt atcattcaag aatatgaggg caagttagca ccttattata ctacttggga
     3841 aatgaatgaa gagggaatca ataactttcc atgtaaaagc attggatttg agtcaatacc
     3901 tcggacacga tttgtgagaa ttttttcgag attccagcgg gtgagtatct catcgtttcg
     3961 accagcggtc aaaccaaaac cgtttgaccg ctgatcgaag cgatgaagtt gaaaccctgt
     4021 ggaaatctcg ccaaaaaaat gtaagtggta gctaggaact aagcttgcaa tgccaactcc
     4081 tccatctgat ttggtgttaa atagttgata ctactatgga ttcgcttgcg attgtaaaat
     4141 ccttcaatgt attgaaataa cgctaaataa gcagcttcaa agttttcata cgcttttgat
     4201 ggatagactt cttctttttt gagtgaggcg tgaaacgatt cgataccggc attatcgtag
     4261 ggacagccct tacgactgaa ggagtgccga atgttcaatt cattcagctt tgcctcatag
     4321 gcttcgctag tgtactgaga acccaaatct gagtggatga tcaagttctc ggagggtgtt
     4381 tggtttaaga gcgcattgtc aagggtttcg ataaccaatt ctttcgtcat ctgcttgcca
     4441 aacttccaac cgatgacttt ctttgtgtgg aggtcttgaa tagtggagag gtaggtccag
     4501 ccatctttta gggtatgaat ataggtaata tctgtcaccc atttttgatt gatcgacgta
     4561 gtggtaaaat cttggtttaa caggttttta cgtccttcac ttttaacttt cgcttgtttg
     4621 ccaggcttgt acttcttgag ggtgactgaa cgcaagccta attttctcat cagtatttgt
     4681 actttcttta aggacaaggt ctcgccacgg ccaacaagaa tcttatgaat tttaggcgca
     4741 ccatagatac ccttgttttc aaagtagatt cctgaaatca agcggtttaa gcgtttgttt
     4801 tctgattggc gcttggaagg tttctttttc ttccagtcat agtagctgga tttcggtgct
     4861 tccaaaacgg tacacatttg ttttacgtca tgatcatgaa catttgattg aataaattcg
     4921 aagacatcac tcatttttac ttttgagcga atatggttaa agcctttttt aggatagtgt
     4981 tttcctcctg catgcgggcc at
//
LOCUS       DAXLPQ010000103         4858 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.106, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000103 DAXLPQ010000000
VERSION     DAXLPQ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.106"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            235..1875
                     /locus_tag="ACF3UO_002669"
     CDS             235..1875
                     /locus_tag="ACF3UO_002669"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFD3658602.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2029..3351
                     /locus_tag="ACF3UO_002670"
     CDS             2029..3351
                     /locus_tag="ACF3UO_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFD3658603.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3413..3844)
                     /locus_tag="ACF3UO_002671"
     CDS             complement(3413..3844)
                     /locus_tag="ACF3UO_002671"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658604.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3908..4744)
                     /locus_tag="ACF3UO_002672"
     CDS             complement(3908..4744)
                     /locus_tag="ACF3UO_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFD3658605.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
BASE COUNT         1499 a          963 c          902 g         1494 t
ORIGIN      
        1 ctatttatct atctaacata tcctttattc ttctactttt ctttctttag catataagag
       61 atacgcatag taatcaagca aggattgttg atataaaaag aacaaatacc gctattttga
      121 tttcttttga ctctattact catataaata aaatttatta tacctgctct ttttgactat
      181 atcctcatct gactcctata cttcgtttgt attaaaactt aggaggaatc attcatgctt
      241 acagggctaa acttattaaa taatcctttt ctaaataaag gaacagcttt tacaaaagaa
      301 gaacgggcaa aatacggaat cactggtatg cttccaagta ctgtccaaac attggaacaa
      361 caatctgtcc aagcttacgg tcaatactta agcaaacaga ccgatttgga aaaacgtatc
      421 ttcttaatga atctattcaa tacgaaccgg acattgtttt ataaattgat gggcgaacat
      481 ttagttgaat tcatgcctgt cgtttatgat cctgtcgttg cggattcaat cgaacaatac
      541 aacgaaattt tcttgaaacc acaagatgct gtatttcttt caatcgacga accagaaaat
      601 atcaaagcaa gtttgaaaaa cgcagcagat ggacgcgaca ttcgtttgat cgttgtgaca
      661 gatgcagaag gaatcttagg tatgggtgac tggggtgtga acggtgttga catcgctatc
      721 ggtaaattga tggtctacac tgccgcggct ggtatcaatc ctgcacaagt cttgcctgta
      781 tcaatcgacg ctggtactaa taacgaagaa ttattgaata atccattata cttagggaat
      841 cgtcatgctc gtgtagaagg cgaaacttac tacgaattca ttgatcaatt cgttcaatca
      901 gctactgaat tattcccaga attgttatta cattgggaag attttggacg aggaaatgct
      961 gcaacgatct tagaaaaata cgaagataaa atcactactt tcaatgatga tatccaaggc
     1021 acaggaatcg ttgtactagc tggtgtatta ggtggattga atatatcagg tgagcaattg
     1081 aaagatcaaa cgatcttgac atttggtgct ggtactgctg gtgtaggtat cgcaaacatc
     1141 cttttagatg aaatgatccg tcaaggtgta cctgaagaag aagcacgcca acatttctat
     1201 caagtagata aacagggttt attgtttgaa gatacaaaag gattgactcc tggtcaaatc
     1261 ccattcgctc gtaaacgctc agaattcact aatgctgatg aattgacaaa cttagaagca
     1321 gttgtaaaag caatccatcc aacgatcatg atcggtactt ctacccaacc tggagcattc
     1381 actgaagaaa tcgtgaaaga aatggcggct cataccccac gtccaatcat catgcctttg
     1441 tctaatccaa caaaattggc agaagcaaaa gcaaaagatt tgattgaatg gacggacgga
     1501 aaagctttag ttggaacagg tatccctgct gctgatgtgg aatataacgg tgtaacttac
     1561 caaatcggtc aagcaaataa tgcgttgatg tacccaggtt tagggcttgg tttgattgct
     1621 tcaacagcta cacgagtaaa tgctgaaatc atttctcaag ctagtcgagc attaggcgga
     1681 atcgttgatg taacaaaacc aggagcagct atcttgcctc cagtagcaaa aatcactgaa
     1741 ttctctcaaa cgattgctga aactgtcgca aaatcagttg ttgcacaaaa attgaatcgt
     1801 gaagaaatca cggatatcaa agaagctgtt gaatctgcta aatgggttcc tgaatataaa
     1861 tctttagaag attaagattg ttatagtaaa agaacataca gaaactttgt atgacgtcta
     1921 aaaagaaaaa agcgactgcg gcaaaacagc agccagccaa ctactgctct tttgccgctt
     1981 ctctttggct tttttcatac gatacagaat aagaaaggat ctgtaaaaat ggcacaaaaa
     2041 acaacaaccg caactgcagt tgaggaaaag aaaaaagaag ggttttggtc aacaaaaatt
     2101 accggcgtaa gtttgcccct ttatttgatc atggtccttg tcctgatcat tgcaatggct
     2161 ttaggaaaat taccgacgaa tatgattggc ccaatcgctg ttttggtcat tttcggtaat
     2221 ttatttcatt ttatcggaac aaaaatccct atagtcaaaa gttatttagg tggtggctcc
     2281 gtttttgcga tctttgcctc tgccgcgatt gctacatttg ggatcttacc tgagtatgta
     2341 gtaaaatcca cagaaaactt tgtcagcaat atgggctttt tagactttta tattgctgcc
     2401 ttgattactg gtagcatcct tggtatgaac cgtaatctat tgatgaaagc ttctgttcgt
     2461 tttattcccg ttgcacttat ttcaatggtc gtctcctttt ttgccgtagg actcgtaggt
     2521 atgcttatcg gaaatggttt tgcaaattcc gttttatata tctcattgcc cgcaatggct
     2581 ggtggtgttg gagccggagc tgtaccttta tcaacgattt atgcaaatgt tttaggtacg
     2641 gacgcttctt ctatcatttc ccgcctgatt cctgcgacag caatgacaaa tgtcctagct
     2701 atcattggtg cagcgttagt tgctcgtgcg ggacaatcaa tgccaaaatt caacggtaat
     2761 ggtaaattaa tggaaaaagg cgaccttggc gatggaaaac ctagaaatgt aaaaccttcc
     2821 attccacaat taggtgtcgg tttgatggta tcattgactt tcttcatctt aggacaaatc
     2881 tgtaactatt ttgttcctaa agtccatgct tacgcattca tgatcattat cgttgttatc
     2941 tgtaaaatcg caaacctatt accagaatat tacgaagatg cagctatcat gttcaacaac
     3001 ttgattgtca aaaacttgac agcagctgtt cttgccggta tcggtattgc gttattgaat
     3061 ctaaatgtat tggcttctgc tttgacatgg caatttgttg tcttatgttt gacaagtgtt
     3121 atcgcgattt cagtagtttc aggatttgtc ggtcgtttgt ttggtttata tccaatcgaa
     3181 tcaactatta ctgctggctt atgcaacaac tcgatgggtg gtacaggaaa tgtagctgtc
     3241 ttatctgcag ctaatcggat ggaacttatt gcttttgctc aaatgggcaa tcggcttggt
     3301 ggtgccatcg ttttgatcat ctcaggtttc ttgatgcaat tactttctta gtcaaaaaaa
     3361 atacctgatc atcaagtatc ggcttgatga ccaggtattt tttgataaaa atttacagga
     3421 ttttcaaaaa tcttttttgc attttatcgg aatgataacc gatgcgttca taaaatcggt
     3481 gtgcttctac tctgtattct gcagaattaa gtcttattgc tgatattcct cgtcttttcg
     3541 cttcttctac gccagtcatc aaggcctttc cgattcctct tttttcagca tgtttagaca
     3601 cagcaagtgc cataatattg aacatcggat cgctgaaaat cgattcatag gactccgctt
     3661 gtacatagcc agctgctttt ttagaagtag gatcttcata gaccaagaaa aaattttttt
     3721 ctggctcctt caacagtttc ttcatttgtc tcaccgtaac ggttaatggt acatcatatc
     3781 ctaattgttc cgcattgatt tctcgtagtg cttctgcatc tcctaaacgc atttcccgca
     3841 acatccaaat caccagccaa tttttatttt tttaaatgaa tttttttatc acagtatact
     3901 ccttttttca cttaaaaaaa gacttttcag tgattttgac ttgcttgaat ccagatcctt
     3961 ctaatgtttg caagatgacg aaagcattgt aaagattgat caaaagaacc acgatgacaa
     4021 tcgcttgaaa aataaaggtc actttttttg gagacaaaac cctgctaaat cttgctcccc
     4081 acaaacctcc aataacagca gcggggataa cataaaacaa catagataaa tcaaagcgca
     4141 taaagctact tgttaaagca atcgttacca attttgccag ttgagaaaag aaaatcgtag
     4201 atagagaata tagtgttgct tcttttattg gcaatgcaaa catcagcatc aacaaagaaa
     4261 cattgactgg tccaccacca atacctaaaa aactagctaa aaagcccaga acccccccac
     4321 atataaggta ccaagtccat gacgtcaaat gaaattttgg ctgatgatgc ttggtgtaga
     4381 agaacgcaaa aaccaaggtc aataccgtca aaaaaatttg gatcagctgc acatgcttct
     4441 cgttttcaaa taactgtaaa aaaacttcga atacaatgtt gccgactact cctccaacaa
     4501 cagctccact agatacccaa ccgacaatct gccaattcag tgatttcccg cttgatactt
     4561 gtcgcacagt cgaaacaatg gacatcgtga ataccgcaac tgttgagtaa aaagaaatcc
     4621 ctgcaacaga atgggcgccg ataagatcaa gaatcggttt gatcaacacg cctccaccca
     4681 tcccggaaat agcgccaact gtgttcgcca gaacgatcac cacaaaataa atcagaccaa
     4741 tcatcttgta tttcctttct cttgtttata tcttttagcg attgttactc ttttctttta
     4801 ttatacagta aaagaaacaa acgaggcttc gaaagctttt ctacttttta aggaaatt
//
LOCUS       DAXLPQ010000104         4841 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.107, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000104 DAXLPQ010000000
VERSION     DAXLPQ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.107"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..422
                     /locus_tag="ACF3UO_002673"
     CDS             <1..422
                     /locus_tag="ACF3UO_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658606.1"
                     /translation="GEKTEIISNSYLSVSINPDFIETVNYVTNFQREMRKVEAMTVLA
                     TQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEGLVGKSMTNSELES
                     IPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            422..1627
                     /locus_tag="ACF3UO_002674"
     CDS             422..1627
                     /locus_tag="ACF3UO_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3658607.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            1643..2287
                     /locus_tag="ACF3UO_002675"
     CDS             1643..2287
                     /locus_tag="ACF3UO_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658608.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            2298..3104
                     /locus_tag="ACF3UO_002676"
     CDS             2298..3104
                     /locus_tag="ACF3UO_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658609.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            3126..3356
                     /locus_tag="ACF3UO_002677"
     CDS             3126..3356
                     /locus_tag="ACF3UO_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658610.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            3913..4188
                     /locus_tag="ACF3UO_002678"
     CDS             3913..4188
                     /locus_tag="ACF3UO_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658611.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            4230..4652
                     /locus_tag="ACF3UO_002679"
     CDS             4230..4652
                     /locus_tag="ACF3UO_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658612.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
BASE COUNT         1819 a          742 c          985 g         1295 t
ORIGIN      
        1 tgggggaaaa gacggagata atatcaaact cttacctatc agtatcgatt aatccagatt
       61 ttattgaaac ggtaaattat gtcacaaact ttcaacgaga aatgcgtaaa gtagaagcaa
      121 tgactgtttt agctacacaa tccccacaag aaatggtgcc agaaaatatg tcttctgata
      181 acttctcgaa actgaagaaa gtctttgaat tttcttctac gaagatcttt atgcgtatgg
      241 atgaatctat tttacgtcat atagaaggat tagtgggtaa atcaatgacg aactcagaat
      301 tagaatccat tcctcaacaa aatcaaggag acgctgtgat caattttggc tcaaaagaaa
      361 ccattcgtgt tcattttagt ccgaacaaac gtcaattaaa attgtttgat ggaggaaaat
      421 aatggaaaac caaaatgaaa gtttaatcaa gcagtatgtt aagcgtcgtg caaagcggcg
      481 cttatttttg tggttgtttg gtacttctgc aggtttgatt actattttga tcactgtgtt
      541 cgtgacccta tttctaatac ttgcggcggg ctcgattgat aattcggatt cagattcaag
      601 cagtggtggc gaagctttta caggagaata ttcggaaggc ttaccgattt ataaagaaat
      661 caaaggaaga ggcccttttt ctgatgagat tgcgcaatat gccgtaggtg cagcagtgaa
      721 atataaatta ttaccaagtg tgatcctttc gcaatacggt tacgaatcag cgtttggtac
      781 atcggcgtcc gcaagaaatg atctcaacta ttttgggatt acttggtttg atggttgtct
      841 gtttcctaaa ggaactgcac gaggaattgg tggcattgaa ggtggctggt acatgaagtt
      901 tcccaactca aaagctgcat tttcctatta cggctttatg gtagccacac aatccaattt
      961 taatgcttgt gtaggaaata aaagccctgg cgcaagctta ttgatcttag gacgaggcgg
     1021 ttatgccgct gcaggaatta cggaagatag tccgtattat acaggttgta tgtcaattat
     1081 cacttctaat aaattaaccg aatatgatga attcgccatc aaacattggg gtgaaggtgg
     1141 caataacaac ggcacgatta ctggtgaatg gacgaatcca ttccctggca gcagtttaga
     1201 taaaagttcc ttcagcggtg gtcaattatt tggaacgaat ccaggcggtg aattccgtcc
     1261 gaacggcttc catgatggat tagattttgg ttcagttgat catccaggaa gtgagattca
     1321 tgcggttcat ggcggaaaag tcgtgtacgt tggcaatcct ggtatttcag gtttgggcgc
     1381 gtgtgtgatc gtgattaatt acgatggctt gaatatggtg tatcaagaat ttgcaaatag
     1441 tacaggaaat tctcgagtga aagtaggcga tcaagtgaaa gttggtcaag taattgggat
     1501 acgagataca gcacacttgc atttaggatt tactcgaatg gattggcgtc aagcacaagg
     1561 acatgcattc attgatgatg gtacatggat cgatccgtta ccatttttga atagcagtaa
     1621 aaaatagatc aggagaaaaa atatggaaaa taaaacgtta aaaatcgtct taacagctgc
     1681 aattagcgtt agtttaatcg gcaatattgc gttgttttgg cagctgaaag aggaacaagc
     1741 agcaaatacc tataaaattg aagaagtggc taaaaacgcg tctgagaagc tcaaaaaaaa
     1801 ttcctctgag gcacaggcga agatcgacaa gttaaatcaa accatcaatg agaaaaacca
     1861 agaaatcgat cagctgaagc aacaagatgg cacaaaagca aaagaggaag taactgaagc
     1921 acaaagaaag acggcagaag agttcggtca attggccatt gataaatcat taagcagaaa
     1981 tgaattaacg gaaaaactaa aagatgtcgc aacccaagaa gtgatcgaca aattaagtcc
     2041 tacagacgat gatcaccaac atgatgatta cggaagttac tcctttacat taggtgacgt
     2101 gcaaacttac gctcaaacaa gcagtgtaaa agaggaacaa aattttgtcg tatttgttga
     2161 ttatacaatc ggcaatccgc aattcaaaga tgtcaaacca caaaaaataa aaggtggatt
     2221 aactgtcact gaaaaacaag tagatggtca atggaaagtc atagacttta gttatttcac
     2281 tcgttaggag gaagaaaatg agtaagaaaa aaggagaaag acaacgtttc aaaaaacgaa
     2341 aaagttatct tagatggctg ggaatcttta tgattctcgg ctttttgatt cttgctagtc
     2401 cgatttatac gaatcagaag gtagatatac cagatgaggt aagcacgaac gcctttttaa
     2461 acacgaaaga gctgacaatg gtttcaaaag aaaaaggagc gaaccagcaa ttagtttttg
     2521 aatttgcgat cgatgatgaa gatcaaagct tgttaaaaga actggctaat cttaattatc
     2581 gcgtagaagt aaagacagct aaaggggatt atcaagcaat acgagccaaa gtgattaagg
     2641 tgtctgatga ttattttgca gtgaagctaa cgcatgtacc agaagaatat atcgccatgc
     2701 gtttaaccat tattcctgaa aaaattgatc caaaagtgga tatgcaagaa ccacaagatc
     2761 tgatttatta cgtgcacgaa gataaggtta aagatcaagt gaaagatgaa gattatgaac
     2821 aacacgcgat caattacaaa gtgaaaggat acaagaaaga acaaaaagca gctcaaaaac
     2881 aaatggaatc tttccaagca accattgatt tgaatgaaga attagtgaag aagctaaaag
     2941 atcaattgcc ttatcaagtc gcagatgatc aggaaaatac tgaaaacaag attaatagct
     3001 accagcaaga aattgaaaca tcgaaaacgc aactgaaaga tcaagaagag atcattcaaa
     3061 aacttcaaga aaaaattgat cgtatgacaa aagaaaagat ttagaaggac aggtggagtg
     3121 aaaaaatgaa gcgaacaaac ttggctgaca aagatacttt cgctgagcag aaagtattga
     3181 ttaaagccta tctcaaagtt gtaaaagcta aagaaatatg tcgagaagtg aatttatcta
     3241 acacaacaat atctgagttg aagaatggtc gaaagaattt agatacttta aaattcagat
     3301 catttgaagc tctatatgta gctgctaaaa aatattttac agctgataac aaataaaaaa
     3361 caggagtatt ttatgtgaaa aaagtatata aaaaatgctt atgaatcagc tatatcacct
     3421 taaccatttg ttaatgagat gggagaaaac attaaccacg attctaacgc aaacatcaag
     3481 cacataaaac atttaacact cctcctttct ggctgaagat ttcaaccaaa caggaagaca
     3541 gcgtatcaat tatagcatac actttttctt aaattcattt ttcatatgac aaaatatttc
     3601 cttctaatcg acaaagttag aaggattttt tattgtctaa atacacaaat aaccttaatt
     3661 tttaaagagc ataaggaaac gtgtacccac tttcaaaata aagtgggtag ataggctgtg
     3721 cctatcacgt ttctgaaaaa aataaatgac cccaaaattt tcaatttatg tgtaggttta
     3781 tgggtagcaa aaatatgaat gtgggcagca aaaagttcat ttgtgggtag taaaattcaa
     3841 atgtgtgtag caatgtgtgt agctacacac attgctacac acgctataac atatagtgaa
     3901 aaggagatat ttatggaagt aaaaataaga gatattgatg aaaaaacgat tcaaagaatt
     3961 gaccgaagat gtattgaatt aagtgaacgc accgggacta aatggagccg aaatcgatac
     4021 ctaaaagttt tgattgaaaa tgattttgac catgaactta tggatcatag aaaagatcaa
     4081 tttgatcggt tgttagaaaa atttgtggat attcaaactt ataatacgaa aattttagaa
     4141 gaatatattg caacaaataa tcaattaatc gccttgttaa ttgaataata aaaatagtat
     4201 tgtgaattta taaaaggagg aaatcaattt tggcaaaagc aacaagaaaa catgtatatc
     4261 tttacgatat gcatatcgaa gtacttgatg aaataatttc tactcatgaa gatatatcta
     4321 attatagtga agcagtcaga catttgtgta tgatgtatga tccaaaaatc gaagaaaaaa
     4381 taaatccaat tcaaattaaa ttgaatgcaa tgggaaaaga aatttctata ttaaccgaaa
     4441 tggtttcaga gtttgcggat cttcatttga aagatacagg aatactaatt ggtacaaatt
     4501 caactgtcta tcaagaagca aaagagcgtg tggaagggaa aataaaagcg aatcaaacga
     4561 aaaagtattc tcctaagatc aagaaaccaa taaatgaatc tgttcatgcc agagtagacc
     4621 cgtttgatcc aacaaagttt ttaaaaagat aaaaagtaga aggggaacat gatgaataaa
     4681 tcgcctgcag tcattctcac ttgtcaattt accttgccca ataaaaaatc tttttcaaca
     4741 tacattgatt atatgacaag agaaaaagcg ctggaagaaa aggaacgacg cacgccggac
     4801 gaagaacagg aactgcaacg aatcaagaat gctttagagg a
//
LOCUS       DAXLPQ010000105         4751 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.108, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000105 DAXLPQ010000000
VERSION     DAXLPQ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.108"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            137..481
                     /locus_tag="ACF3UO_002680"
                     /pseudo
     CDS             137..481
                     /locus_tag="ACF3UO_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
     gene            512..832
                     /locus_tag="ACF3UO_002681"
     CDS             512..832
                     /locus_tag="ACF3UO_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFD3658613.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(861..1325)
                     /locus_tag="ACF3UO_002682"
     CDS             complement(861..1325)
                     /locus_tag="ACF3UO_002682"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658614.1"
                     /translation="MVTYNWIKLREHPELVKQSAKWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(1454..2703)
                     /locus_tag="ACF3UO_002683"
                     /pseudo
     CDS             complement(1454..2703)
                     /locus_tag="ACF3UO_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(2732..3049)
                     /locus_tag="ACF3UO_002684"
     CDS             complement(2732..3049)
                     /locus_tag="ACF3UO_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3658615.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(3075..3395)
                     /locus_tag="ACF3UO_002685"
     CDS             complement(3075..3395)
                     /locus_tag="ACF3UO_002685"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3658616.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(3796..>4751)
                     /locus_tag="ACF3UO_002686"
     CDS             complement(3796..>4751)
                     /locus_tag="ACF3UO_002686"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3658617.1"
                     /translation="RYGDRVKNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYH
                     KVLATAKAVEIYRSGNYGGRIGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPM
                     VKGYYTEEFLELCQKQSIYFDPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEE
                     TPFHPERYYEVFDLPGKKMNNSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGRE
                     HEERYMDEKGIVQDDYRIEFIGQHLRYLIKATEEGANCEGYMLWAFTDCVSPMNAFKN
                     RYGLVRIELNDERSRTLKKSASWYQTLIDKRELDLPDEIYK"
BASE COUNT         1461 a          991 c          790 g         1509 t
ORIGIN      
        1 ttcgctagag tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg
       61 tgaatgtgtt gtggtaactc tattctacag aagggacttc cttttttcta tttacacaaa
      121 atattttaca ctctcagaaa aagcgaaaaa tttagtaagc ttacaaaacg gcacaatctc
      181 tccattacag atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt
      241 ttatatgact ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt
      301 caagcatgga caggcaccaa ttatccatct aatgccaaaa atttacgaaa tgattgcaga
      361 aggactattc gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca
      421 agcatatgag atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg
      481 aattcagtaa aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga
      541 gatcgaaata ggaaaagaag aagatatcga aatacgagga cgtcgcttcc gcttctattt
      601 ccaaaatcgt tacacattga tctcactggc tgtcgattta ttaaccggga ttttctatat
      661 ttttggaagc cttgcttcct taactaaaat ccccgatcga tatggcacct atttttattt
      721 ggctggtgct attttcttga cgattcgtcc tattctcaga atcgtaagga acatttttat
      781 ttacgacgaa aaaaaagcaa tgaagagaac aagcaaaaaa aaagaggcat gagatttgaa
      841 aaaatctcat gcctcttttt tcaccctatc gtatcacttt gatacagacg agcggtcgtc
      901 ccactttctt ccttgaccat tgtcaaaaat gtccactcgt atcgttcata aaacgtggta
      961 tgatctgtaa ttaagtaaag tttttcgtac ccaagttgat gcatttcttt tctgatttcc
     1021 gctaatatcc gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa
     1081 agatttggtg tcaaatcagg gcggttatgg aagtcgtttt caataacgcc cgctcctccg
     1141 acgatggttt ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg
     1201 attccagtac gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac
     1261 cacttcgcac tttgttttac taattctggg tgttctctta atttgatcca gttatatgta
     1321 accaatgttt aaacctccga ctaaaataaa acgtttacaa aaattataca agtctttatg
     1381 aaaattagca atgacaacaa tagtgatgta aaaaaaacgg aaaacaatca cttgttctcc
     1441 gttttttgat taatcaagca tctaaagctt cttttcttct ttcttggatc gtagctacct
     1501 tgacgaacgg tagatagatc aaaatagaaa gaaccaaatt gacagcggct agtacaccac
     1561 ctgcaatact ttttgttgcc aatacaccgc caataattgg tggagttacc catggaggca
     1621 taacggtagc tgctggcact aaacctgtag aagtcgcaaa gtaagcaaca ctaactaaga
     1681 ccattggtgt caaaataaat ggaatgaaca tgatcgggtt caacacgata ggtaacccaa
     1741 acatcgttgg ttcattaata ttgaagacac ctggcgcaat cgacaagttt gttacaacca
     1801 tatatggttt gtttttacgt cctactaaat aaatagctaa cagtaaacct aaagttgcac
     1861 ctgttcctcc taagttgaca aagctgtcaa agaaaggttt gttcacgata aacggtgcgc
     1921 tatgtccagc tgcgattgca ttaacgtttg cttcaatggc tggcgcattg attgtttgca
     1981 tcaaaggatc gaccatattc gctccgtgta aaccaaagaa ccataagaat ggtgtgataa
     2041 atgcaagcag taaggcagat ggataagagt ttgcaagtcc cataaatggt tcttggacca
     2101 ctgtatagaa agaacctacg atatcatcaa caccgaatgc agcaaaaatt gcagcaacta
     2161 aagcaaacgc agagatagtg atcattgctg gtagtaatga agcaaatgct tttgcaactg
     2221 ccggtggcac accatcaggc attttgatga tcaatttttc atttccgctt aaacgtacaa
     2281 agatttctgt tgaaataatc ccaacaataa tagcaataaa taaaccgttt gagctcatac
     2341 ctaatgctcc gcctaaagcg aagaaagagc ctaaagaaat cacacctgcg gaaacaccgt
     2401 cttttcggta gccgttagct aaatgataag caagaaagca atcaagacag aaagaatggc
     2461 aaatgtaccg ttccaagcag cagccccgaa tcctttccat gattcaccac caaaaattga
     2521 gttcatcaat tcttggaacc cgggaatcgg taagttattg atcattactg ctaatgctcc
     2581 taagatcatt aacggcatac tcaccataaa tgagtcccga atcgcaacta aatgccgttg
     2641 tgcaccaatt tttgatgcta caggtataaa atgtttctcc ataaatgcaa caaatttatc
     2701 cataaatctt ccctcttttc tttactgtag attacgcgtt caatcgacga tacagatcaa
     2761 tgatctcttt tgctaaatct gtaaaagcta tggatgtcat cagatgatct tgactgtgga
     2821 ctgtcaaaag cgtgacttca acgtgatttc cttgtgcttc ttgtgtcagc atctctgttt
     2881 gagagtgatg tgcttggact aaagattcct ctgcatcttt gattttttca tctgctaaag
     2941 tgaaatcacc ttttttcgca gcagcaatcg cttccattgc atcgcttttt gcatttccgc
     3001 caaacatgat cagacccatg atggcttcta gatttttttg atcttccatt tattgtatcc
     3061 tccgataatt tttattattt gtttattagt ttttctgctt ggtcgagtac tttttcacca
     3121 ttcatcatgc catagtcagc catattgatt atatctaaag gaatgccttt aggtgctagc
     3181 ttttcagcaa attgattttg cataaagcgt acttgcggtc ctaaaagtaa aacgtctaca
     3241 tttttagatt ctagttgatt atccgcatct gaagcagata cagcaaagat gtctgcttcc
     3301 attccttttg cttctgctgc cttttgcatt tttgtgacta ggagacttgt actcattcca
     3361 gctgaacata caagcatgat tgttttcttt tccattttaa acacgttcct ttctatactt
     3421 acacttgtat ataagcaagt agcgtgccaa ctttgaaagc gctttaaaaa gttgatatca
     3481 tcacatttaa ggtctatacc aagttgcata cacactaaaa aagaaagtgc acactaaaca
     3541 cacaaattaa tttttattac cttttttctt ttaacgtgca caaaaaaagt tgtgacacaa
     3601 aacttgtcac aacttttttt cgaataaacg gtattcaaaa gcttgcatct gcggtaataa
     3661 gtccaaccaa gttaaaaaca taagatgttg tttttacttt gctattctta ttacttgatg
     3721 caggacagct ttttcacaac ctcttttatt tcaaataacc agtaaataca atgaacatct
     3781 acaaaaaact tctatttatt tatagatttc gtcaggcaaa tccaattctc tcttatcaat
     3841 caaagtctga taccacgaag cagatttttt caatgttctg cttcgttcat cgttcaattc
     3901 gattcgaact aatccatatc gattcttaaa tgcattcatt ggtgacacac agtcagtgaa
     3961 tgcccataac atatagcctt cgcaatttgc gccttcttct gttgctttga tcaaataacg
     4021 caaatgctgt ccgataaatt cgatacggta atcatcttgc acgattcctt tctcatccat
     4081 ataccgttct tcatgttctc ttcccatacc gttttctgtt atcagccaag ggatattatg
     4141 ataattttct tttagataca tggctatatc atacatgatt ttcggataga tttcccatcc
     4201 cctggaatta ttcattttct tcccaggtaa atcaaagact tcataatatc gttctggatg
     4261 gaaaggtgtc tcttcattcc attgataacg aggagcgcga acgcgtttag gataatattg
     4321 attgattcca aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg
     4381 atcgaaataa atcgattgtt tttgacacaa ctccaggaac tcttctgtgt agtacccttt
     4441 taccatcgga tcaaaaaata ctcgattata aaacaaatca tacatataag cagctttttg
     4501 gtcttctgga gaattagatc gagcatagac catttcagga tttaaaatac agccaatcct
     4561 tccaccataa tttccgctgc ggtaaatctc tactgcttta gccgttgcta aaactttatg
     4621 ataattccac atcatccact tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa
     4681 atagcaacgc gtttggggaa cgattggttc gttgaatgta aaccagtttt ttaccctatc
     4741 accgtaacga t
//
LOCUS       DAXLPQ010000106         4431 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.109, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000106 DAXLPQ010000000
VERSION     DAXLPQ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.109"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            86..1507
                     /gene="gndA"
                     /locus_tag="ACF3UO_002687"
     CDS             86..1507
                     /gene="gndA"
                     /locus_tag="ACF3UO_002687"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFD3658618.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            1700..2386
                     /locus_tag="ACF3UO_002688"
     CDS             1700..2386
                     /locus_tag="ACF3UO_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3658619.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            2383..3888
                     /locus_tag="ACF3UO_002689"
     CDS             2383..3888
                     /locus_tag="ACF3UO_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3658620.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         1544 a          729 c          921 g         1237 t
ORIGIN      
        1 atgttgttct ttagtttgca atgtagccgt gttaagctat aatgtaagag attagggaga
       61 aatcccgtat gtaggaggag ttcatatgtc aaaacaacaa atcggcgttg tcggtatggc
      121 cgttatgggt aaaaatctag ccttgaacat agaaagccgc ggctattcag tggctttatt
      181 caatcgtaca ggggctaaaa caaccgctgt agtagaagaa cacccagata aaaatttcaa
      241 agcaacatat acaatcgaag aatttgtaga atctatcgag aaaccacgtc ggatcttgct
      301 aatggtcaaa gcaggaccgg caacagatgc aacaatccaa gagttacttc ctcaccttga
      361 taaaggcgat attttgattg acggaggaaa tacattcttt aaagatacga tgcgtcgtaa
      421 tgaagagtta gccaactctg gcatcaactt tatcggtaca ggcgtttccg gtggtgaaga
      481 aggagcttta aaaggacctt caatcatgcc tggtggacaa aaagaagcct atgcgctagt
      541 tgcaccaatc ttagagcaaa tttctgcaaa agcagaagac ggagcaccat gtgtcacata
      601 tattggccca aatggagccg gacattatgt gaaaatggta cacaacggta ttgagtatgg
      661 agatatgcaa ctgattgctg aatcttatga cttaatgaag aatattttaa acctttcagt
      721 agaagaaatg gctgatatct ttaaagaatg gaatcaaggc gaattagaca gctatttgat
      781 agaaatcact gctgacattc tgacacgtaa agacgatgaa ggaacaggta aaccagtagt
      841 agatgtgatc cttgatgcag ctgggaataa aggaacaggt aaatggacaa gccaaagcgc
      901 gcttgactta ggtgtgccac ttccattgat cactgaatct gtatttgccc gctatatttc
      961 tgcttataaa gaagaacgcg tacaagcaag caagattttg tctcgtacga acgattttga
     1021 gttcacggga gacaaaaaag aattggtcga aaaaatccga gaagcgttgt atttcagtaa
     1081 aatcatgagt tatgcccaag gatttgctca attacgtgtc gcttcaaaag aatttgattg
     1141 ggacttgcca tttggtgaaa tcgcaaaaat ctggcgcgct ggatgtatca tccgagctcg
     1201 attcttgcaa aaaattacgg atgcctatga caaaaatcct gagatcgaaa atttattgct
     1261 agatgattac ttcgttgaaa tcacgaaaaa atatcagcaa tcagtcagag acgtcgttgc
     1321 cttggctgtc caagctggcg tacctgtacc gactttctca tcagccatcg cttacttcga
     1381 ttcatacaga gcagaacgtc tgcctgcaaa tataatccaa gcccaacgcg attactttgg
     1441 cgcacatacc tatgaacgtg tcgacaaaga aggaatcttc cattactcat ggtaccatga
     1501 agaataatag tctttcggct gttaggaaat gagaaaataa aaagaggacg aaagagctga
     1561 agtcgattgt tatgagtaga cttcagctct tttttaaaat tgctatccat gataaaatga
     1621 ctatagattt ttaagcatat tatcggtata atgatagagt ttttaaaaag ccagtagaat
     1681 agaaaggata aaataataaa tgagcaatat tctaatcatt gaagatgaaa agaacttggc
     1741 acgatttgtc gagctagagt tgaagcatga agggtataac gcagaagtcc actacaacgg
     1801 ccgaactggt ttagatgcgg cattaaataa tgagtgggat gccatattgt tggatctgat
     1861 gctcccagaa ttgaacggtt tagaagtctg cagacgtgta cgccaagtca aaaatacacc
     1921 aatcattatg atgactgcaa gagattctgt gatcgatcgt gtatctggac ttgaccacgg
     1981 agcagatgac tacatcgtca aaccatttgc tatcgaagaa ttattagcac gtcttcgtgc
     2041 attgttgcgt cgaatcgata ttgaaggcga taaaaatgtg gctaaacaaa ctactattac
     2101 ttatcgcgat ttgactatcg aaaaagaaaa ccgtgtcgta cgtcgcggaa atgaagtaat
     2161 tgaactaaca aaaagagaat acgagttgct gcttacttta atggaaaacg tgaacgtggt
     2221 attagcacgt gacgttttac taaataaagt gtggggatac gaaacagaag ttgaaacaaa
     2281 cgtagtggac gtatatattc gttatcttcg caacaaaatt gacgttcccg gggaggaaag
     2341 ctatatccaa actgtacgcg gaacaggtta tgtgatgcgc tcgtgataaa gccgaaaaaa
     2401 tcggaaaaaa gagaactgaa agggccctcc ttgacaatca agtgggcctt tgcgagttct
     2461 ttcttcatat tcgttgtgtt tacaattttc gctgtcatta cctataaatc atctatcaat
     2521 ctgattgtgg caaaagaaag aaacaatgta gagcgtacga tttcagaagt agcttctcgt
     2581 ttggctaact cggatgaaga actgacatta gtaaatacgt atcgtaatct gacgaaagcg
     2641 acaaatgacg gagatgaggt cgtagatcat acttcactgg tcgaaggaaa cttaatgaag
     2701 atcgattcct ttatagctga gctagggcag ccatcaatgg atctttatgt ttatgatttg
     2761 gacgagaact tgatttttaa aacccatgaa aacagtcgaa acctgattca gactacacgt
     2821 aaagttccaa cgatcgttac actagaagga aaaactggct ttttatctat ccagcctata
     2881 tattctaaag gtacaagaga aaagatcggc tatgcgcaaa gcttctatga attatcttct
     2941 ttctatgata ttcgaaataa gctattattg actcttattg ttttagaagt tgtttctttg
     3001 atcttaagta gtattttagg tttcttttta tcttcttatt tcttaaaacc actcaaggta
     3061 ctcagagata caatggatac tatacgtaaa gatccgcaat cagatatcca catgcctgaa
     3121 atcgacacaa atgatgaatt ggcagattta gctgaaatat tcaatgagat gcttgaccgt
     3181 atgcgtttgt atattgaaca acaagagcaa ttcgtggaag acgtatctca tgagttaagg
     3241 acacctgttg caattattga agggcatctt agtctgctaa atcgttgggg gaaagatgat
     3301 cctgagatat tagaagaatc attaagcgcc agcatgcaag aaattagccg tatgaaaagc
     3361 ttagttcaag agatgctaga cttatcaaga gcagaacaag tagatgttca ttatgcgaat
     3421 gaaacaacta aaggaaaaga agtcacctat caagtttata ataatttcaa gatattatat
     3481 ccagactatg tgatcacttt agatgatgat ttgacaaaag aagtgaccct gcaaatttat
     3541 cgtaatcact ttgaacaatt aatcattatc atattggata acgcagtaaa gtattcaact
     3601 acacgaaaag aagtccatat ctctatttct tccactctga atgaatttga gatcgcgatt
     3661 caggactttg gcgaaggaat acccaaagaa gaccttaata agatcttcaa tcgtttttat
     3721 cgagtggata aagcaagagc tagaacgaag ggtggaaatg gtctggggtt gtctatcgct
     3781 aaacaactgg ttgaaaacta taaaggacgt atcttagcag aaagtgtagt agggcaaggg
     3841 acaattttta gaatctttat tcctatcgca aaggcagaag acaagtaaag catgtgcttt
     3901 acttgttttt ttatatatcc aacaaagaat aaggtacaaa atacaagcaa gttagaaatt
     3961 cagggatgtc attataaaaa aaactagcga acaattaaat agaataacat ccgttaatta
     4021 aacgtaagta gcttttagat gaacgaaaaa acaatgaaat gctgtaatat tcgtgtttaa
     4081 aaataataaa taaaaatagg gaattttcta ttgcaatttt ataaagagat tgctatatta
     4141 ttatttgttc taaatgattc ctttaaggtg tcactaaaaa ttataaaaaa tagggttgac
     4201 gcacttttga tgtcatgtta taataacgaa gtcgtttgga tgaggtagct aataaagctt
     4261 gattttatcg aaaaaaactt cgaaaaagtt gttgacaaat aacaataaag atgatatgat
     4321 aatcaagtcg ctgctaatga gtgacaaaga cgtttagaaa aaataaacaa agaagttgtt
     4381 gacattctct tctgaatctg ataagattaa agagttgttg aaacaaaaag a
//
LOCUS       DAXLPQ010000107         4417 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.110, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000107 DAXLPQ010000000
VERSION     DAXLPQ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.110"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            59..913
                     /locus_tag="ACF3UO_002690"
     CDS             59..913
                     /locus_tag="ACF3UO_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFD3658621.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="ACF3UO_002691"
     CDS             1010..3259
                     /locus_tag="ACF3UO_002691"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3658622.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4417
                     /locus_tag="ACF3UO_002692"
     CDS             3262..>4417
                     /locus_tag="ACF3UO_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3658623.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          807 g         1429 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actagag
//
LOCUS       DAXLPQ010000108         4372 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.111, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000108 DAXLPQ010000000
VERSION     DAXLPQ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.111"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(83..1051)
                     /locus_tag="ACF3UO_002693"
     CDS             complement(83..1051)
                     /locus_tag="ACF3UO_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3658624.1"
                     /translation="MSKKRTIVNEWEKLTALSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1496..2902)
                     /locus_tag="ACF3UO_002694"
     CDS             complement(1496..2902)
                     /locus_tag="ACF3UO_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFD3658625.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSENEIEW"
     gene            complement(3124..3486)
                     /locus_tag="ACF3UO_002695"
     CDS             complement(3124..3486)
                     /locus_tag="ACF3UO_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658626.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDDLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3490..3798)
                     /locus_tag="ACF3UO_002696"
     CDS             complement(3490..3798)
                     /locus_tag="ACF3UO_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658627.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERIMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            complement(3807..4226)
                     /locus_tag="ACF3UO_002697"
     CDS             complement(3807..4226)
                     /locus_tag="ACF3UO_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658628.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
BASE COUNT         1241 a          979 c          604 g         1548 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga cagggctgtt aatttttccc
     1021 actcattcac gattgttctt tttttactca tattcagttc ctcctcaaag aaaaaagaga
     1081 tttttggaaa gaatttccag agttcacgta actctaaaaa ttcataacca tcaatctcta
     1141 gtcttgaaga aacctaaaaa tattcgtata atgaatttga gttacggaac tagtgtggtt
     1201 agtttccgta aaggtcgaga acgttggtag cgttgctcga cttatttttt tgctcttttt
     1261 ccagttcatt tgtttgctaa ctcaataata gcacttctct ttagctatgc aaataccaaa
     1321 aaaataaaac cgcacccttt gaaaagggcg cccccaaact tcgctaacgc taagttggcc
     1381 aaaaaatgga cttgccattt tttagcaaat gtcagcttca ggggctagtg gtttagccgt
     1441 caactcctta tcctcggcac aaaccgcctc cggtaccgtt gactgcacat cgtggctacc
     1501 actcaatctc attctcagaa cgctctaatt tatgctgtga gacgttttga cgataaaata
     1561 aggttttctc ctgctctaat acttctaatt cctcagaaag ccccatatcc ttttctgcaa
     1621 gaccaaaacg gatagacaaa cgagtgatcg atttttgaaa tgcgtttttt aatcgctcta
     1681 aacgctggcg taaagagcga ttttcttctt tcagcttttt attttccact tgtaaatctg
     1741 ctaattgttt tctaccagac aaatgacgct cttcttccaa tgtagctaca tactcattta
     1801 attctgtatt ttgctcaagc atctgtaaat attgctcact catgttatca gcatttctct
     1861 tggcatttgt tgctctcgta gctcgttgat acaaatcaac aaaatcattc ccagataaat
     1921 gatacgaacc atcaggaagc ctcttgaaac tttctaaagg aaccatatct ttttggaaaa
     1981 tgaccgccat ctcttttttt acattcagca tatttttctt ctcttcttca atcttcgctc
     2041 tctcagaagc catcagagcc ttatcacgct cgttttcttc tctttgccta taaatatacc
     2101 tcaactcatc agaaacgctc tcacgctctt ttacagccgt ttggcgcaat tcagaaattt
     2161 cactcatgat ttctttgtat tcgtgaatat ctttaatttt gttggtaccg acaatatccc
     2221 ttttccaacc gtaatcattc attaatcgtt ctatagagtc aacttcttga tttctaaaat
     2281 tattgaaaag cactcgacca ttatctttat cagcgtgtat cccttgttga accagtgctt
     2341 tattaaagct cggctgcttt tgaacacccc gtttataacc ttcagcaacc ggcacaatat
     2401 tcaagtgcag gtgcggactt atttcgtcat tatgaataac agcattataa acagccaaat
     2461 tagggtttct ctcttgaaac tccttgtaat actgaaccaa aattttattg gcaatcactc
     2521 gattttgttc agcttgttgt ttcgatatgc cagtagaaga accatctgct cgatttgtct
     2581 ggaaatcatc taaaatgcct atttgcacaa taaattctcg ttgaggttcc aactttttat
     2641 ccttgcgcac tttcgctaaa tagtcctcga tttttctatc ggctcttttt tgtttcgcat
     2701 tatatttttc taccacttcg ccaaacaatt cctcatattt atctgctaga ttcgtctgct
     2761 ctaaataaat attttcatcc gatttcgtga agtcaatgtg cttatgccaa tcattggttt
     2821 tctggcgatc agttaactca cgattattat gagaaatact tgtattcttc gttccttttt
     2881 taaatgaaat actaaacccc aagttaaaac cctccttcgc gctgtcgcta ataaaaagat
     2941 tgtaaacctt tctgttactc tttgtcaaag agtaacattt tcctaattgt gacatggatg
     3001 tcacaattcc aaacgctctc cgagggtttt cgctgtcaca agtgacaacg aaaaaaggag
     3061 ccgaaagcgt atcacgctat caactccttt tatgctttat tttgcttcac gcaaaataat
     3121 cgcttatcgt aaattcacgt cattaaatat tgacgtaaat ttactctcac tcatctgact
     3181 tttcttattc ggtatcactc cgaataagtc gtcagattca tcgggataat ctcgttcgct
     3241 tggcgctgat ttttcatcag caagccactc attatccact gttttttcgt gttgctgatc
     3301 gtcagaaatt gacgataacc accgctcaaa atcagcaaaa gtttcaaacc caaaacgctt
     3361 gcgaagagcc ttgcccattg cagcattttc tttctcaatc aagcgttttt tctgttggcg
     3421 aagtttcgct tgttcttttt ttaatttttc ttcttgcgct ttaatatctg ctaaagtcat
     3481 tcccataaac tacatctcct tttctttgga attaataacg gaaatttggt ttaactgcat
     3541 aacatgactc attaatttca accaaaattc tttttctgat tcatcagttg tttgcgctaa
     3601 atgcttatga acaaattcat tagtcaaaac tgaagatttt gctagatcag cattgataac
     3661 cgagttgaga acatccataa ttcgttcaag catttcacta taattatctt catccggcaa
     3721 attcaaataa tcagctaacc gttcatacat caattcaatt ctatcgactg tttcttctct
     3781 caaatcaatt ttatccatgt cacacctcac ttccagaatt gccaccattt tcgatttttt
     3841 aattcttgat tttctagtaa caactgatcg tttttttgtt gctgaagcaa agtcaatttt
     3901 tgttggtcac gaatcatttc cgttaattca gaaatatgcc tatctttttc cgctaattgt
     3961 tcacgcaaaa attcattttc tttttctaac gggaaatcat tgcctgcatc attgaccggt
     4021 aaatcaccag tcaattgacc accttttgac cgataaattg accgcacaac accaatcaat
     4081 tccttgtcta acatgataac cccattatct ttataccgag caaggtcata acctgcattg
     4141 accagttgat tgcgcactgt atttttagat atacccaact catcagcaag gttttttatg
     4201 gtcatttttt ctggcaaatc agtcattatc ttctccgtta ctttcagcta ccccataaac
     4261 atatttaaca gcatgcttag ggataatgat tggggaatca attttattat ttttcaaaat
     4321 caactcatac tgcgttacat caagtaactt accggacatt tttttgctat cc
//
LOCUS       DAXLPQ010000109         4318 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.112, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000109 DAXLPQ010000000
VERSION     DAXLPQ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.112"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            287..694
                     /locus_tag="ACF3UO_002698"
     CDS             287..694
                     /locus_tag="ACF3UO_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658629.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="ACF3UO_002699"
     CDS             708..1109
                     /locus_tag="ACF3UO_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658630.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="ACF3UO_002700"
     CDS             1111..1482
                     /locus_tag="ACF3UO_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658631.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1820)
                     /locus_tag="ACF3UO_002701"
     CDS             complement(1518..1820)
                     /locus_tag="ACF3UO_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3658632.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2078..2191)
                     /locus_tag="ACF3UO_002702"
                     /pseudo
     CDS             complement(2078..2191)
                     /locus_tag="ACF3UO_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2574..3807)
                     /locus_tag="ACF3UO_002703"
                     /pseudo
     CDS             complement(2574..3807)
                     /locus_tag="ACF3UO_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
     gene            4064..>4318
                     /locus_tag="ACF3UO_002704"
     CDS             4064..>4318
                     /locus_tag="ACF3UO_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3658633.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAF"
BASE COUNT         1447 a          715 c          767 g         1389 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctagttttc gcagcaggaa ttttgaaata gttcttatta
     1681 gaatagtaga gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaattc
     1741 catactttat aaaaatcttt gataaatcta ttcgaagggt caaatttaaa ccataattgt
     1801 gtttttcctt ccatcagcat aaaagttcac ctcaaaaaga gtatacgaac gaatgttctt
     1861 tttgtgaagg cggaatttaa tatactgaat aatagaaaac aagtacttgt gccaaattat
     1921 gtgccaaaaa aattcgaatt caacaaaatg taaacaaata gaaaaccttc tatattaaga
     1981 tttcctgcaa taacaaacac aacagaagac gtgtaatagt tagtcaggaa cgtacaaata
     2041 acccctgtat cctttgcggt acagggggtt attttgtata agtagacatt gtagtttcta
     2101 aactgctatg tcctaaacgt ttcgatacgc taagtatatt tactccttga taaagtaaaa
     2161 tagatgcatg cgtatgtctt agtccctcaa taaacagtcg aagagaaaat aggcaaaaat
     2221 tgattactaa agaaaaactt actaggtcga cggtgtagtt gattttcata cttcaacaga
     2281 ttcgaattaa acgatttcga ttggcttata ccagtcctat ccgacgaaag atatatcgtt
     2341 cttaactcta gcggtataac ttgaagcttt acgtaaagcc aatgggaatg aactggagat
     2401 gactttttat tatttttagt aatagctgat gggttaatac ttacaacttt ccttttcaaa
     2461 gtaccatata aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt
     2521 agatccttta ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc
     2581 caatcgccat ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc
     2641 atcttgtcag atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct
     2701 gctaattctt catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct
     2761 agtgctaagt gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat
     2821 tgagaaatag gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca
     2881 tctgtatcaa gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaatgact
     2941 tttccatctt taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc
     3001 tttgtacttg aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc
     3061 gtcggcatat ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa
     3121 agatggtttt taggcaatcc gataatgata tctgtaccgg gagcagtata gtgcagggca
     3181 gaaaattgtt ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc
     3241 catgctaaga cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat
     3301 gcctcaactt gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca
     3361 gccgcagcca cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt
     3421 agtgctttgc cagccgctga ttgataagac ggctactcga tggctatcta caccagcaaa
     3481 tgcatcggga tcggcagaaa caacactgat cctgcttgct cctttttcaa gccattcatc
     3541 cgcttgatcg attttagatt gtggtacatt ctcaatacga tccgttgcag catgtaaaag
     3601 aaattctctt tggatctggt cgtcagtcca ttgaacgata acctcagcgg ctcctagttt
     3661 ataagcttct tgtgtgatca atcgagcaag gggtgcctgt tccacgctga tctgtaaaac
     3721 aactgtgtgt cctttttctg tggctacgcc agtttctgca attaagcgtg catatttttt
     3781 tagaagttca ttaaaatcag ataacataat aaaaattcct cctcaccatt ttttctggta
     3841 actattagca tgataccatt taattatgat tcaaacaatg aggcctttaa ataaaaaaaa
     3901 gaggttattt ttttaaggtt aagtttcatg atatatgtta ctacttgcta tttcagcttg
     3961 tgaagaaaat caaaaactaa ttttgcatat caaaaaaaac atgttacaat gaaattaatc
     4021 aatggtggaa gcgttataaa aaaattaagg agattaaaaa aatatggcaa gaaaaaagac
     4081 gattactaga gaacagattt tggcagctgc ttatgaagta gctgccaccg atggatttac
     4141 acgatttact gcgagaaaca tcgcgaacaa aatgaattgt tccacgcaac cgatttatct
     4201 tgagtttaaa aatatggatg acttgagaca agctcttttt gagcagatct atgatcattt
     4261 acaatatgaa gtgttcactg ttgagcatac agggaatacg attatcgatc ttgctttt
//
LOCUS       DAXLPQ010000110         4310 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.113, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000110 DAXLPQ010000000
VERSION     DAXLPQ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.113"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(65..1285)
                     /locus_tag="ACF3UO_002705"
     CDS             complement(65..1285)
                     /locus_tag="ACF3UO_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3658634.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1916)
                     /locus_tag="ACF3UO_002706"
     CDS             complement(1305..1916)
                     /locus_tag="ACF3UO_002706"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFD3658635.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="ACF3UO_002707"
     CDS             complement(1959..2891)
                     /locus_tag="ACF3UO_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFD3658636.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3312..4172)
                     /locus_tag="ACF3UO_002708"
     CDS             complement(3312..4172)
                     /locus_tag="ACF3UO_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3658637.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1230 a          866 c          707 g         1507 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaacaaacaa cacatttttg tgtgttgctt atttccctct aactatcgtt
     3121 ttctatttga tggttaacct acttaaaata aatactgcaa cgacaaacgg agatcaagca
     3181 tgctttgtaa cgtattttac gataattacg actttatttt attactctat cttgctgcca
     3241 tacccgtcta tccctaatca tctttggtga attttttcaa agttagcata acaaaaataa
     3301 gtattttttc cttagttaat caatagtatc atttttttca tatgatttaa ttcatcaatt
     3361 aattttttgt ttttattaat tttagcaaaa gctagtgcat cttgaatcaa ttcgagcact
     3421 tctgccttcg acttattttt agcctgtgcg ttcttcgcta attgggcagc agctcgtgct
     3481 aagtaataag tcaaatggtt atccgaacaa atatcgattg cgtaatttag tagtgcatca
     3541 cttgtttcca aatcaccgtc ttgcgcaaaa aaaacaccac aatgaaagac gatatttaac
     3601 acccgccaga tatcttctgt tgtacgaatc ggatacgtat aaattttttc aaacactcga
     3661 ttgaaataaa cttctgcttt ttccaactct ttttctctag catagaccat tccaatacct
     3721 gtatatgcca ataaacgaaa caacgtgttg gctgtttctg ccatcaacaa ctgatcaaaa
     3781 tggaacaaca catccgtaat tggtgcattc gtaaaaatca tttcaaatcc ttttagatag
     3841 tagtaacgtg caatcagctc agactcgtca attaccttgg gatcaatggc tgctaaaatc
     3901 tgtgtcaatt gttcatattc actcgtaatc agtgaaaact ctgctttttc tagctgttca
     3961 tcaagttgtg tattgatcac gttcatcgaa gaaaaaagtt caactaacgg aagattgatt
     4021 cgattacata atttgattaa aatttttaac gaagggactt gaccattgtt ctcaaattta
     4081 cttaatgttg cttgtgtaca aattccttca gacacttctt tttgagataa gttggcagcc
     4141 tttcttgccg taataaattt ttcaatgttc attattttct ctccaatcag acctcacacg
     4201 aaaatcattt ctgtctcgat tttagcatgt tttctttggg aatgctttag gttctgttgc
     4261 aaagttttaa ataaagaata aagtccctta cggtatctat gatttaagct
//
LOCUS       DAXLPQ010000111         4257 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.114, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000111 DAXLPQ010000000
VERSION     DAXLPQ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.114"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            148..333
                     /locus_tag="ACF3UO_002709"
     CDS             148..333
                     /locus_tag="ACF3UO_002709"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658638.1"
                     /translation="MSTLQEKQLQFNPHLLRNEEIFRGASIYKIITIDMMKQIKARDK
                     QIELAENIVDYLLHTNF"
     gene            complement(417..3383)
                     /locus_tag="ACF3UO_002710"
     CDS             complement(417..3383)
                     /locus_tag="ACF3UO_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFD3658639.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            3529..4104
                     /locus_tag="ACF3UO_002711"
     CDS             3529..4104
                     /locus_tag="ACF3UO_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658640.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
BASE COUNT         1311 a          787 c          740 g         1419 t
ORIGIN      
        1 tgtcagaaca ggcatttatc ccgctttgat aaggtttatc actctattcc ttcttcaccc
       61 gttgggtgaa gaaaaaaata tacaaaaaga gcacactcta tgttattgta aagtcgatca
      121 aaacaacaaa aacaagaggt gtgctcaatg tcaactttac aagaaaagca actacaattc
      181 aatccccatt tgttgagaaa tgaagaaata tttcgtggag caagtatcta taaaatcatt
      241 acgattgata tgatgaaaca aataaaagct agagacaagc aaattgaatt agcagaaaac
      301 attgttgact acttattaca tactaatttc taagaatata aaggggtagc gtcaggaaaa
      361 tgcggattta caacgctaag cctattttcc tgacgaatcc ctcgttttta acaacgttaa
      421 gaaagtttta gtggtcttaa agaatttaat gagactactt tctctgagtt aaaatggtat
      481 tctcctagta aattaatatg ttcccaacct aagggcgaca tatggtgtaa caaatcttca
      541 ttaaagctac ctgtccgttt tttatattca actgctgttg ttaggtggag agtattccaa
      601 atacttatag cattgataat tatgtttaaa gcactggctc tttgcaattg atgctgtatg
      661 gtgcgttctc taagctcacc ttgttttccg aagaaaatag ctcttgccaa tccattcatg
      721 gcttctcctt tattcaatcc tctttgtatt tttcttctta atgattcatc cgatatataa
      781 ttcaaaataa agatcgtttt ttctattcgg cccatctcac gtaaggctgt agctaagctg
      841 ttttgtcttg aataggaacc tagcttcccc ataataaggg atgctgaaac tgttccctcc
      901 cttatagaat gagctaatcg caaaacatcc tcataatttt ctttaatgac ctttgtattt
      961 atttgtccac gtaaaatggc ttctagtttt ggatactcac ttgctttatc tatcgtaaat
     1021 aattttgagt ccgataaatc ccttattctt ggggcaaatt taaatcctaa taaatgagtc
     1081 agtccgaata tttggtcagt gtaaccggca gtgtctgtat aatgttcctc tatgtttaga
     1141 tccgtctcat gatgtaacaa accatccaaa acatgaatcg catctcttga attagtatga
     1201 ataatctttg tgtagtaaga agagaattga tcacttgtaa atcggtagat ggtggctcct
     1261 tttccagttc cataatgtgg atttgcatct gcatgtagtg atgaaacacc tagctgcatt
     1321 ctcataccat ctgacgaaga tgttgtaccg tcgccccaat agaaaggcaa ttgtaattta
     1381 tgatgaaagt ttactaatat ggcttgggct ttattcatgg catcttcata catgcgccat
     1441 tgagatacat tggctagttg cttatatgta agtccgggtg tggcttcggc catcttgctc
     1501 aagccaatat tcattcccat tcctaaaagg gcagccatga taatgattgt ttcttcctta
     1561 tctggttttc gattattgga agcatgagtg aattgctcat gaaatcctgt tatatgggcc
     1621 acatccatga gtaaatcagt taattttatt cttggtagca tctgataaag gcttgcacta
     1681 aatttttttg cttcttctgg aacatctttt tctaagcgtg caagtgatag ctttcctttt
     1741 tcaagagaaa ccccatctaa cttattggaa ttggcagcta accactttaa cctttcatta
     1801 aagctgctgg ttctctccgt tatataatct tcgaatgata aactaactga taatctcgta
     1861 ttccccttcg attgattcca tgtatcttcc gaaaacaaat attcctcaaa atccctatat
     1921 tgtctgctgc caacaatgga aacatctcct gcccgaacat gctcccgaag ttctgttaaa
     1981 acagccattt catagtaatg acgattaatt gttgtaccat catcctcgta taaatgtctt
     2041 ttccatcgtt ttgaaataaa atccacaggt gagtcatcag gcacttttcg ctttccagat
     2101 tcgttcattc ctcggataat ctcaacagct tgtaaaagtg gctcatttgc ctttgtagaa
     2161 tgaaattcca atactcttaa tagcgttggc gtatattttc ttagtgaata aaaccgtttt
     2221 tgcagtaagt ctaaataatc atagtcggca ggacgtgcaa gttcctgagc ctcttctact
     2281 gaagagacaa aggtattcca ttcaataacc gattctaaaa ccttaaaaac gtctaatttt
     2341 tcctctcttg ctttaattaa tgcttgtccg atgttcgtaa agtgtataac tttctcattt
     2401 agctttttac cgttttgttt ctggatttcc tcttgagcct tacgaccttt tgataacaaa
     2461 ctaagtattt gcctatcatg aatttcaaac gctttatccg ttagctcctg agtaagttgt
     2521 aataaataga tggttaatat cgaataacgt ttattttctt gaaagtcacg gaatgcatac
     2581 ggctcgtatc ttgagcctaa gcgagacagc tgcaacaggc ggttacggtg caaatgacta
     2641 atttgcactg tttctaaatc cattcctcgt atgtattcga gtcgttctat tatttttaga
     2701 aaagtttcgg gtgaaggatg acccggtggc tcttttaacc aacccaatat cgttttattg
     2761 gattcggatg gatgctgcga ggtaataatc ccttcaagct tttctttttg ctcatttgtt
     2821 agagatttac taaccgtatt aaatagcttc ttttcagcca ttgcccttgc ttcccacacc
     2881 attctttcaa gtgtagtgat agcaggcagt ataattttgt tttttcttag aaaatctatg
     2941 cattcatgca gtagatgaat ggcatcacca ttttccaaag ctaattgatg aaggtactta
     3001 aatgtcattc gatattcact cagggtaaaa gttacaaagt cgtattcact tcgaatttct
     3061 ttcaaatgat cccaaagtgt attttccctt tgaggataat gatcaagcga ggatggacta
     3121 acaccaatct gtttcgatat atattgtatg accgaatctg ggatgctttt gatatgagtg
     3181 tatggccaac cgggataccg aagaacagct aattgaacag caaatcctaa acggttttct
     3241 tccctccttc gcttattaac tatttctaaa tcccgtttgg aaaaagtgaa gtaggtcccc
     3301 agtatccatt catcttcagg gatttgcata aaagcctgtc tctgttccgg tgtaagcaat
     3361 tctctacctc tcgcaatttt cattcagtat cattccattt ctgtattttc aatttattag
     3421 ttcaattata tatcaataga gtgtactcta ttgatacaaa tgtagtagac tgataaaatc
     3481 atagttaaga gcgtctcata agacttgtct caaaaatgag gtgatatttt gcggaaaatc
     3541 ggttatattc gtgtcagttc gactaaccag aatccttcaa gacaatttca gcagttgaac
     3601 gagatcggaa tggatattat atatgaagag aaagtttcag gagcaacaaa ggatcgcgag
     3661 caacttcaaa aagtgttaga cgatttacag gaagatgaca tcatttatgt tacagactta
     3721 actcgaatca ctcgtagtac acaagatcta tttgaattaa tcgataacat acgagataaa
     3781 aaggcaagtt taaaatcact aaaagataca tggcttgatt tatcagaaga taatccatac
     3841 agccaattct taattactgt aatggctggt gttaaccaat tagagcgaga tcttattcgg
     3901 atgagacaac gtgaagggat tgaattggct aagaaagaag gaaagtttaa aggtcgatta
     3961 aagaagtatc ataaaaatca cgcaggaatg aattatgcgg taaagctata taaagaagga
     4021 aatatgactg taaatcaaat ttgtgaaatt actaatgtat ctagggcttc attatacagg
     4081 aaattatcag aagtgaataa ttagccattc tgtattccgc taatgggcaa tatttttaaa
     4141 gaagaaaagg aaactataaa atattaacag cctcctagcg atgccgaaaa gccctttgat
     4201 aaaaaaagaa tcatcatctt aagaaattct tagtcattta ttatgtaaat gcttata
//
LOCUS       DAXLPQ010000112         4157 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.115, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000112 DAXLPQ010000000
VERSION     DAXLPQ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.115"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            179..775
                     /locus_tag="ACF3UO_002712"
     CDS             179..775
                     /locus_tag="ACF3UO_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3658641.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="ACF3UO_002713"
     CDS             899..2698
                     /locus_tag="ACF3UO_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFD3658642.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="ACF3UO_002714"
     CDS             complement(2976..3188)
                     /locus_tag="ACF3UO_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658643.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="ACF3UO_002715"
     CDS             3650..3799
                     /locus_tag="ACF3UO_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658644.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="ACF3UO_002716"
     CDS             complement(4052..>4157)
                     /locus_tag="ACF3UO_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658645.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          707 c          729 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAXLPQ010000113         3930 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.116, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000113 DAXLPQ010000000
VERSION     DAXLPQ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.116"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..789
                     /locus_tag="ACF3UO_002717"
     CDS             <1..789
                     /locus_tag="ACF3UO_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3658646.1"
                     /translation="KFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESI
                     SELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPK
                     EYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVET
                     IDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKK
                     HEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            800..2909
                     /gene="topB"
                     /locus_tag="ACF3UO_002718"
                     /pseudo
     CDS             800..2909
                     /gene="topB"
                     /locus_tag="ACF3UO_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            2925..3074
                     /locus_tag="ACF3UO_002719"
     CDS             2925..3074
                     /locus_tag="ACF3UO_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658647.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3155..3751
                     /locus_tag="ACF3UO_002720"
     CDS             3155..3751
                     /locus_tag="ACF3UO_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFD3658648.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3764..>3930
                     /locus_tag="ACF3UO_002721"
     CDS             3764..>3930
                     /locus_tag="ACF3UO_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3658649.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGS"
BASE COUNT         1436 a          682 c          849 g          963 t
ORIGIN      
        1 aaattctttg aaagtagtat tgatctgtta agttacgctg cattgaatcg ggagaaacta
       61 caagatgcct ggttagtttc gatggacggg ttaaaacatc atgtaatcag tcattacgtt
      121 gaagagtcga tttctgaatt aagacgaaaa caaacatttc ctcaatcgat tgaaatatgt
      181 gtggacaatg atcgtgcagg acatattttt tatgaaaaag aacagatgaa gggaatcgtt
      241 gatcctttta ccaataagaa aatccgttgt gagcgaggaa ttccaaatga ttggcaagta
      301 cctaaagaat acaaagctac ttatgaagca gtcgcaaaag aaatgagtgt tgaacctgaa
      361 gcaattatgg ccatacacaa aactgaaact aatttacagc tgacaaatca attggtgtct
      421 gctcatgatg ttcaatctac gtttggaaag atgttggcga agggcgaacc agtagaaaca
      481 attgatttga aagaagcatg taccacggtc gcgaaggaac tgaaagtatg tgaacgcgca
      541 gatggaacat acaactttga tcgtttttat agtagaaaag ccaacataaa agacgttaat
      601 gcaggaatcc ttctttccta taaagcagaa caatactaca aaggctataa aaagcatgaa
      661 catgaatttg tacctgaagt gaaaaaggat tggaatgatc aattgaagca tgagatccag
      721 caacaagaaa tcagaaagca aaaacgtgcg atgttgtttc aacaaggcag acaacaagaa
      781 agggagtgaa gtcgtcacta tgaaaaccgt cattttagca gaaaaaccgt cacaagcgaa
      841 ggcttatgcc gatagctttt ctaaagctac ccgaaaagat gggtattttg agatccaaga
      901 tcgattgttt acaggagaaa ctgtgatcac gtatggtttt ggtcatttag tcgagttaga
      961 ttcgcccgat atgtacgatg aaaaatggaa acaatgggca ttagaacatt tgcctatttt
     1021 ccccaatcaa taccactatc atgttcctaa agataagaaa aagcagttta gtgtcgtcaa
     1081 acgacagctg cagtcagctg atacgattgt gatcgcgact gatagcgatc gtgaagggga
     1141 gctgattgcc tggtcaatca ttcaacaagc aggcgccaat caaggaaaaa cctttaaaag
     1201 actttggatc aactccttag aaaaagaagc catttatcag ggattccaac agttacgaga
     1261 cgcagaagag acctatccaa aatttgaaga agtacaagca cgtcagatcg ccgattggtt
     1321 aattgggatg aacggtagcc cactgtatag tttactcttg cagcaaaaag gcataccagg
     1381 aagtttttct ttaggtagag tccaaacccc aacactctat atgatttatc aattgcagga
     1441 aaagattaga aacttccaaa aagaaccata ttttgaagga aaagcccaag taatcgctca
     1501 aaatggcgca tttgatgcga agcttgatcc aaatgaaacc caagcgacac aagaagcatt
     1561 tgaagcctat ttaaaagaaa aaggtgttca attaggaaaa cagccaggta cgatccttca
     1621 agtcgaaaca gagaaaaaaa gtgcggctag cccacgtctt ttttctttat cgagccttca
     1681 gtctaaaatg aatcaactca tgaaagctag tgccaaagat actttggaag ccatgcaagg
     1741 gttgtatgaa ggaaaatatc taagctatcc gcgaacggat accccttata ttacggaagg
     1801 ggaatatgcg tatctgttgg atcacttaga cgaatacaag cattttttaa aagccgaagc
     1861 gattccgact cctattcata caccgaatag tcggtatgtg aataataaga aagtccagga
     1921 acattacgcg atcattccta caaaaacggt tatgacagca gcggcttttg aacaactaag
     1981 tccactgcag caggctattt atgaacaagt gttaaaaaca acggtggcca tgtttgcgga
     2041 aaagtatacc tatgaagaaa caacgatctt gacgcaagtt cagcagcttc agttaaaggc
     2101 aatcgaaaag gtgccgctag atctaggttg gaagaagtta tttggaaaag agagcgacgg
     2161 aaaagagaag gaagaagagc cgctacttcc taaagtgaca aaaggagaaa tggtgacggt
     2221 ggatctacaa gttcttgaaa aagaaaccaa gccaccacaa ccttataccg aaggtacgtt
     2281 gatcactgca atgaaaacag ctgggaaaac cgtggatagt gaagaagcgc aatccatatt
     2341 gaaagaagtg gaaggaatcg gtacagaagc gacacgggcg aatattattg aaaccttgaa
     2401 acaaaaggaa tatatcaagg tagagaaaaa taagctcgtg gtgacgaata aagggatttt
     2461 gctttgccaa gccgtggaaa aagagccgct gcttacgagc gccgaaatga ccgccaaatg
     2521 ggaaagctac ttgttaaaga tcggtgaacg aaaaggaaca caaaccactt ttctagccaa
     2581 tatccaaaaa tttgtctctc acttattgga agtcgtacca gggcaaatcc aatccactga
     2641 ttttggatcg acgttacaag aagtgaaagc agccagtgaa aagcaagaag ccgcgcgtca
     2701 tttaggaatt tgtccaaaat gccaggaaca agaagtctta ctctatcaaa aggtggcagc
     2761 ttgtacgtct gaagcctgtg attttaaaag gtcagaaggg ttcatttgaa gcaacgattg
     2821 ttttaaaaga agacttcact acaggctttg aattttctga aaagaaaaaa acgaacttca
     2881 agaaaagaac acgccgcact gcaaaataat ggagggttaa tcttatgcgt aataccacac
     2941 acaaacaaca agaaatcgaa aatcaaaaag ccaaaattcg ttcagaacag gaaaaaatgc
     3001 gtgccagcaa acgaagactg cagcaattga agaaccagca gaggattcaa aaagaaatcg
     3061 aattagatcg ataaaatctt cctaactatt gtatacgtat aaacttatgt tatactgttt
     3121 ttataagttt atacgtatac aaaggaggga gaaaatgaca aaagcaatgg tatacaagct
     3181 gctagaagaa tttaatggaa ctttggcttt gaaggatgcc aaaaaagcgg gcatttctcc
     3241 tgtaacgatc aaacgtatgg tagatcgagg ggagctggat cgagagtatc caggtttttt
     3301 caccttacct ggtcaatttc ctgatgaatt gtttatggcg caaaaaaaat atgaacgcgg
     3361 cattatttca catattaccg cgttagattt gtatgattta acagatatga tccctagaca
     3421 gatcgatctg actgtacctt acggttatca cgtttctgaa aaaggattga aggaattcgc
     3481 agttgagcta cactatacaa aagcggaatg gtatgaatta ggtaagattg aaataaaaag
     3541 tcgctatggg aatcctatta tagcttatga tccagaaaga actttatgtg acatttggaa
     3601 tccctggtat accgttgagg atgaaatcaa agtaaaagca atcaaaaact atatggagtc
     3661 ggacagaaaa aatcttagaa aattgaatga gtatcgacga attttaccaa cagacaaaac
     3721 gatgcgttct tatattatgg ctttaaatta aaggagaaga tacatgacac ctacgcagtt
     3781 aaaagcaaaa gtgaagaata tttctagaga aaaagaagtt gatccgcagc ttgttttaag
     3841 acattttatg atggaaaaat tcttggaaaa aatctcagag tctccttatc gtgaaaattt
     3901 tgtgttaaaa ggcggcttct tgattggctc
//
LOCUS       DAXLPQ010000114         3926 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.117, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000114 DAXLPQ010000000
VERSION     DAXLPQ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.117"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(112..387)
                     /gene="prgO"
                     /locus_tag="ACF3UO_002722"
     CDS             complement(112..387)
                     /gene="prgO"
                     /locus_tag="ACF3UO_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFD3658650.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(359..1312)
                     /locus_tag="ACF3UO_002723"
     CDS             complement(359..1312)
                     /locus_tag="ACF3UO_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3658651.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1924..3417
                     /locus_tag="ACF3UO_002724"
     CDS             1924..3417
                     /locus_tag="ACF3UO_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFD3658652.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3552..3848
                     /locus_tag="ACF3UO_002725"
     CDS             3552..3848
                     /locus_tag="ACF3UO_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFD3658653.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
BASE COUNT         1307 a          646 c          703 g         1270 t
ORIGIN      
        1 tgttgtatac ccccaaacaa tacacatatt ttgaaggatt aggattaata aagctaaaaa
       61 tatagtaagt atactaaata tatttactat atctagtata cttactatat tttaatcttt
      121 tgatcgtcta ttatatataa tccgttcctc gtcgtttaaa gtatcaacat aggcgtccat
      181 tgcaagtttg actatttcat acataggaat atcttttgca taactaagat cccgaatggt
      241 ttttagtacg ggaggatcta cttgaactgg ttttctttct ttcgcagtgt actttcgttc
      301 ccctaactcg acattaatat catctttaat tgaaatatct tcagcaccaa ttttcttctt
      361 atctttgttc gttggtaata atgccattta gtttaatctc ctttccaaga ggtaggatat
      421 gattggccat tgagtcagca tatttaggtg tataatcaaa tccttcaata tcaccatgtt
      481 gttcatagta ttcaattctt tcttctaatt ctgtaaagat gtctgcaaaa atagcccacc
      541 atcttcgatc tacataatca tttaattgga taccattctc accatacatt tctaaccgat
      601 ccgagccttt aacaatgctt ttaaaaatgt ttgattcacc atacttatca attgtttttt
      661 gatagtttgc gtgttgagag gaacgtcgca ctgagaaaag aacaggcaaa attccaatga
      721 tttgaagatg agactcttca aaattcgtga caatcggaac taaaacttta ttaataaaat
      781 cttctgttcc ttccattgcg taccgtttta attcttgcat tgcaataata taatctgcag
      841 cagttaagaa tgcacgaacc acattatctg ttgatggtgg gcagtcgata aagatataat
      901 cgaaattttt tctcaattct tctaaaggtt taatgaaggc caatgatctc ttacgacgat
      961 caggatattt ttcggacaag tattcattaa gttcttcaga tccaggagag ccagccataa
     1021 tatataaatg tggacttact tgagtaatac ctgaaaccca gtcccctttt ttgattgctg
     1081 cagacatgga tcgatcaaag ctagtaattt gatacgttga tccaatgttg gaagtagtat
     1141 ttctttgttg gtcataatca attagcaaca cgtctttttc aaaaagttga ctagaaacaa
     1201 tcgctaataa atcattgtct gtagtcttac caatgccgcc ttttctacct gtaagcatta
     1261 caacttttcc tagtttatct gatgttttaa atgcagtccg taagttttcc atagttccct
     1321 ccaatttcct atactaaata tatttagtat acttcatata cttaatatat tcgatatatc
     1381 taatatactc caaattgata agaattcaga ctttataagg aatatagtgg atatactaaa
     1441 tatatttgct atattcagta tatcagatat attcaaaatg tcaaaatata tttgtgcgtt
     1501 ttgcgttgac aatttagagt gaaaagaggt aaacttaatt ctatagaaac cacagataat
     1561 tcactattta caaagtagca aaagcagtgg tactctttaa acagaaaaat tacataaaaa
     1621 aaagagacgg aaataattga ttttagcaga atcaattatt tctgaatcac atggttagga
     1681 catgtgttca cgctcgtctc aagaatatgt aagtagctac caactactta tattaaaagt
     1741 tgatcggata ccttttccga ttgcctttat tctaccaaaa aaaggcgagc aactcaacag
     1801 aagaacgttt atttagtgta cttaaattaa atattcttaa acactgaaga gagaacacat
     1861 actatggctg agattaaagc taaactgtgt tctctttttg tttgagaaag gacgttacaa
     1921 tcgatgttga gcgaaattta ttcagctatt cttaaaaacg gcttacgtac atacaaatat
     1981 cgaaacagca ccatgaaacc tgcaggtcat attgattcca gtaggagtgg tgctatcttt
     2041 gcgtaccgta gcaagcaatt aatgaatgtt gggcgtggta tggtcattac ttcggaagaa
     2101 gctattttag agaacgaaaa gaaactaacg cattggacac ctaataccta tcgctttggt
     2161 acttatgcgg atgattatcg aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa
     2221 atcaacacat ttgtagttga tatcgattca aaagagaacc atcaaggcga aattatttta
     2281 gcctgtttag atcaagtggg ctacatgcca acgctaattt tagaatcaga tcatggttat
     2341 caagtttatt ttgtactaaa gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg
     2401 atcgatgtag caaaaaaaat ttcaaaaaca attcgtctac agttggctga aaaattgtcc
     2461 ggagtggatc taggatgtaa ccacttcgga attgctcgat tcccacaaga aaataatatt
     2521 gtttttaaag aaatgaacta tcagtattct tttgctgact ggattcaatg gtcgatgaag
     2581 cttgaatcag atcaaaaaac aaaagaagat cgagaacgaa aactaattgt ctttcctgag
     2641 aaaaaagaaa ttcgtcaagt agatgaaccg tggttcgata tgttacttca taaagcaaac
     2701 atcgtcggcg gagaaggacg tcttggtcga aataatgtga ttttcacgct ttctttagct
     2761 tattactctt caggttatgc attggatact tgcgaataca atatgttcac attcaacgaa
     2821 cggttacagg aaccgctatc tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct
     2881 ggtaattatc aagcagcaag cagagaattc attattgaat tgtgccagca atgggtttca
     2941 ccaaccttaa aaaataatga tctgttcatt caacgacgtg gctggtggaa atttaaaaag
     3001 ccacgagatc aaagaaaata tagtcataaa aatgaatgga aagaagatct attggcttat
     3061 ctaagcgaaa aaagtcttgc tagtgagcct tatttgaacc tgtcaaaaaa agaattggct
     3121 tcacaactaa cgatgcccaa gcgaacactt gataagatct taaatgagtt acgagaggag
     3181 aataaagtct tctacaaggt aacacgagga agaaatggcg gaatgatcat tgcttcagtc
     3241 aaaacgttgt tcgcgagggt tattcaacta agtaaagaaa agagactaga ttattcaaca
     3301 aggatcacag aggtatttgg actcaacgag agcttagtag aagagacatt tagacaatta
     3361 tcaaccccct tgaaccctct taaagaagtg aatctttttg aagtagatac aggttgaaaa
     3421 ataaaaggtg caaattgcct tatacaatat atctatgata cttctgtagg tgttgctccc
     3481 tttgcctagc tacgtgtagg tggtatactt ataactgcgt atgcagtctt atgtatcatg
     3541 gaggaagttg tatgtcgtta aaaaattatg tctattcaca tcctgttaat gtgtttatca
     3601 ttggtcgttt gggattatct gtggaagtgt tctgtgagct ttatggtttt aagcagggga
     3661 ctttgtcttc ttgggttacc agggaaaaaa cagttgcttc tttgccgatt gagtttcttc
     3721 atgggttgtc cttagcttct ggggagacta tggatcaggt atatgattgt ttgtgtgtgt
     3781 tagagcagga gtatattgag tataaaatag ctaacgagtt aagaaaaagg aagaagtata
     3841 tccagtagta gtttttattt actcttaatt gtcaaattaa gttagacaaa tcatcaatac
     3901 ttacgtaact caaaaatact tccaaa
//
LOCUS       DAXLPQ010000115         3841 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.118, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000115 DAXLPQ010000000
VERSION     DAXLPQ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.118"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..101)
                     /locus_tag="ACF3UO_002726"
     CDS             complement(<1..101)
                     /locus_tag="ACF3UO_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3658654.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQE"
     gene            176..454
                     /locus_tag="ACF3UO_002727"
                     /pseudo
     CDS             176..454
                     /locus_tag="ACF3UO_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
     gene            597..818
                     /locus_tag="ACF3UO_002728"
     CDS             597..818
                     /locus_tag="ACF3UO_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658655.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            834..1676
                     /locus_tag="ACF3UO_002729"
     CDS             834..1676
                     /locus_tag="ACF3UO_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658656.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1739..3541
                     /locus_tag="ACF3UO_002730"
     CDS             1739..3541
                     /locus_tag="ACF3UO_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFD3658657.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3600..>3841)
                     /locus_tag="ACF3UO_002731"
     CDS             complement(3600..>3841)
                     /locus_tag="ACF3UO_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3658658.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1361 a          557 c          768 g         1155 t
ORIGIN      
        1 atttcttgaa cttcacgata gctaaggtta taacgaagat agtagcccac ggctacaata
       61 atcacatcct gctgaaattg ctttccttta aaatgattca tcgtcattcc tcctgctatc
      121 tttttctatt attctacctt atttgatagt agatttaaaa ctttgcaaca gaaccaaaga
      181 actcatcaag ctggctaata agggtcaaga ttatgaacat ctagcagatg agattgatga
      241 gctgagagac aagcgacagc tccttttagt agaagatgcc tccctcagtg gcgagaacga
      301 gcgaatcaat gagctgattg aatttatccg caagaacaaa ttccgtacct tagagtacga
      361 tgataagctt gtaaggaaga taatccagag cgttacagtc tatgaagaac acttcgtcat
      421 atccttcaaa tctggcatcg aaatggaaat atgaaaacca gaagtaaata gcccatgatt
      481 ctacagtaga gtcgtgggtt ttcttttgct tgctgattat aataatattt taataactat
      541 tgttattata aaccaaatga tttataatat tcttagcgta aacttggagg tgctgtatga
      601 ctacggcaga aatgattaaa gaactgtgtg agcaaatgaa tataagtgtt tccgaacttg
      661 ctagacgtat tggacagact ccacagaatt tcaataagaa attacaacga gaaacggtaa
      721 ccttagatga gttgaaagcg attgctgatg tgctaggtgt caagtttgtg caggctttta
      781 tattgcctga tggcaatgaa ataaagatag gtaattagga ggtgtaattt gtattgaaaa
      841 tcataacaat aaatgatgtt gagtatgctg tatttgctgc taatgaaggt acttccaaac
      901 cacaacctca tatcatagaa acgaaatctg gtactattcc agaaggaaaa caactgagtt
      961 tattaaaaga atatcttaag cagaatgata tttccccaat aaaaggagca acaacatatt
     1021 ggtgcattga caaggttctt aagcttgatt caagtaaaga aaaaactata agtgaaacaa
     1081 tccataaaca aaaatactta tctttaactg aagaaaatat tgagaaacag cataagtttg
     1141 taggtgcaag ctctaattat gggaaagaag gtctaataat acatgatgtt ttgaatgcat
     1201 ttcctcttca taatgattta aatactattg cgatgaagat tgcggtaatt gatgtaacaa
     1261 attcaacaca tctttctcaa tataagagca ggttgtctct atatgatttg gctaaagtaa
     1321 ttctggagat tccaaatttt gatgatcggt tggcaaaagg agatcctcag ttgataaata
     1381 ttatcgcaag gaacattggt gcagttaata tgttctcatt tgcatccaag tactgtacat
     1441 atcataatgt ggaagtgtgt gggagagatg attactccat ctttgatggt atcgttaaaa
     1501 atactcttcc acactatatc caaggactaa ctacgaataa gattgatacg tggcgaagaa
     1561 gttttgatta cgaggcattt aacgaatgtg ttggaaaact acttgatgaa aataatatac
     1621 atattccttt tagaagaaga aagttagatc acttcttgtg gtatgcgaat aggtagaata
     1681 taagaaaaag gcatcgtaaa agtgattctg gataaaatta atgggggagg aaataatagt
     1741 gggattattt gattttctaa agaaaaaaca aggaaaggtt agtaaacacg ttgattatca
     1801 actggcttct agtctatttc gtactggtaa agtttttgct gaaaaattgg aagtggacat
     1861 atcaaatgta gatgagtttc gtaaaacttt tatcgctttt gatgtggaaa caactggcct
     1921 aaattcttct tcagatagaa ttgtagagat tggtgcggtg ctatttaaag aaggagttcc
     1981 aattcaatca ttcggaactc ttgtcaatcc aaaagttaga attgcagcct cagcttcggc
     2041 aataaataat ataactaatg aaatgctaaa ctctgctcca aatgagcagg aagtttaccc
     2101 ccagttggta gaatttttag gagatgcact agatggaaaa atcactatgt gtgcacacaa
     2161 tgcaagtttc gattttggat ttttaagtaa cacattttct agacttgggt atgatgctaa
     2221 aattaagtat gttgatactc tgagtctctc tagaaaacat ataaaaggca ttgtaaatca
     2281 taagcaagag actgtagcgg aatatttcgg attaataaat gacactgccc atagagcgga
     2341 atcagatgca gatatatgcg gaaagatttt ttggggtgtt ttagatatta ttgaggagtc
     2401 gttggaagaa caaaaaaagc aaatagaaaa gatgactcca gacataaaag aacttgaagc
     2461 ttgtgctttt attcaagata ttattgagaa aaaaggatgc gacaccagtt ggatcaggta
     2521 tcgaaaaaac agtaataatt atgtcgatgt aacttgtcta tatacattct taaagtttaa
     2581 gtttgctaag aagggaaatt acatcattat tagaaaagat gctacaaatg gaattgattt
     2641 acctatagaa ccttgtactg taagtgaagg cggtacaaca aatgtgcgag tctattttcg
     2701 tagccccttt gacttaacgc ctctttcaaa ttatattttc agtgcttata gcgattgtta
     2761 taattctatg aatgaatata tgagtgttag taattacact aaaaaagaag cagagcaaag
     2821 ccttagtatg ctgaaatcta tttcaaaatc agcgatgaaa gagttattat tcgatgcaaa
     2881 aaatcgtgga tatgatgaga ctgaagttaa cctaaatatt gaaaaagtga tatctagaga
     2941 agatgtaatt attaacgggt tgcataatcg agtttcatta aacaagatac gaaatatagg
     3001 gaattgggag aaaggatttg atgcaggtta tccatattgg gaacgtggag aaactgctag
     3061 gaaaaatggc aaagtagatg aagctattgc actttttgat aaagctcgat ataacggcta
     3121 tgatgctcct gcgctatatg attcttatgc taaagcttat cgaaaaatta aggattacga
     3181 taatgaaatt ctcattcttg atgaaggaat tatgcgtaaa acacggcacg atgttggtac
     3241 tttagaggct cgtagggata aggcaattaa gctattattt gctaaacaag aggcagagcg
     3301 gatagctaag gaaaaatctg attttctaaa agcgaacaaa aaagaggatg cgattagtga
     3361 gcctagcaag aagcgtggaa gacagattat tcaaatgact gatgatggaa caataataaa
     3421 agaattcgat actatagctt ctgctgtaaa agaagttggc gttaactcaa aaagtattag
     3481 ggatgctgca aatggagttc aaaaacatgc tggaggatac tactggaaat acaaagatta
     3541 gcagataatc taagataacc taggatcttc ttaatagata cccgtggtgc tagttaattt
     3601 taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg acttaataga
     3661 acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac agaacgtgag
     3721 ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtcccaac tgtttttctt
     3781 tgttttccaa gtaagctgtg gtctagtttt tctgatttat ccatgttttt acgtggcgga
     3841 a
//
LOCUS       DAXLPQ010000116         3764 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.119, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000116 DAXLPQ010000000
VERSION     DAXLPQ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.119"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(73..366)
                     /locus_tag="ACF3UO_002732"
     CDS             complement(73..366)
                     /locus_tag="ACF3UO_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFD3658659.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            403..588
                     /locus_tag="ACF3UO_002733"
     CDS             403..588
                     /locus_tag="ACF3UO_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658660.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            complement(767..1945)
                     /locus_tag="ACF3UO_002734"
     CDS             complement(767..1945)
                     /locus_tag="ACF3UO_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3658661.1"
                     /translation="MENMSRFKKHITATGKITWYFQAFRTTRRGFNSKREAQLAYLEM
                     EKQHRNKQKRIASNDKFNVVSQKWFEYYRSLNEQKRATYDKREEQVKILNRWIGDKKL
                     SSLSSEELQKFLFILKEKGIDGIDVGYAKNSLQSLVQVLNMIFKYCKKKNLINENPME
                     FVKMPKYQLTVEDLKESVNSLEDKFLTVDELRTFLNYGIIYEELPMSVLFHVLFYTGC
                     RVSEALALQPQDIDFERNEILFYKQTAVKGKSKDFRIETTKSVSSARRVPVTPLVMEK
                     LHELIDVLNKTKRNSNFVVDETYLFVYLDPGKRGVPYRREYVNDHVKRCVERCGINKN
                     FHTHLARHTMASLVAEYCSWDVLKDRLGHTDSTTSKIYRHLTSNERIKPLLAFDSLEN
                     "
     gene            complement(2048..2359)
                     /locus_tag="ACF3UO_002735"
     CDS             complement(2048..2359)
                     /locus_tag="ACF3UO_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3658662.1"
                     /translation="MSKNNNKNNSSELENCLFNPKKLEDSINKVKRINDLPLVLTNKD
                     LKEQFQISDSTLNRLIKLDNFPRCWFGIKGHYLRDDILEWIKKGKEEYFCDQFRLLRE
                     L"
     gene            complement(2711..2956)
                     /locus_tag="ACF3UO_002736"
     CDS             complement(2711..2956)
                     /locus_tag="ACF3UO_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658663.1"
                     /translation="MVDKPKKWQYPLVPLSIILSALEEDPISIKMILKHYDNYIAKLC
                     LTNGFNEVGQFITYVDEYMLRQLEVKLIEAILKFKVN"
     gene            complement(2950..3351)
                     /locus_tag="ACF3UO_002737"
     CDS             complement(2950..3351)
                     /locus_tag="ACF3UO_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFD3658664.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNEAKSIRKRNTRIKDNEEPLN
                     DVNEGKYPQTNFDEQDVYFLFGMEILISDQKLSAAIDQLSDIRRKIILLYYFADFNDA
                     EIGRILNMSTSGIWYQRTKAVEQLKMGYDLW"
     gene            complement(3588..>3764)
                     /locus_tag="ACF3UO_002738"
     CDS             complement(3588..>3764)
                     /locus_tag="ACF3UO_002738"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3658665.1"
                     /translation="TTQVGKQAKKAKMLPKTGEEDTNMITIFGGLLLLGSLGLIDYKK
                     RESKKSSSRIERSK"
BASE COUNT         1188 a          691 c          476 g         1409 t
ORIGIN      
        1 aaagttcaag tatgcggtgt agaaccaata tcgcatactt gaactttttt caatgagtat
       61 aaattaaaac ttctaatttt caattcccat catctgatat gcccgaccgt ctgaacttct
      121 tttgaaaaag ccaaatgtga ttagataacg tctttgttcg acataatcgc cactagaaaa
      181 tacgttcagc agtatcgaat taacctctgt ttctgtataa gtcactccat ggtcaaagcg
      241 tttcaagact tctttcaata ggatgtattt cttttttgtt gaacttggta cttgttttac
      301 ttttccatca ttcatgaatg tgtctaaaac tttcatcttt tcttgctccg tataagtata
      361 aaccatcttc tttctccttt tgattctaag aatactccat ttatgttaga atattctgga
      421 ttttttatta aagcggttac tcttaagaaa gatattatca tagtgctctt ttttttacta
      481 ctacttatag gtagatttat tctaatccat tattctcccc taccaataat taaagaaaaa
      541 actggatcag ggtgttcaaa ttacatgcta agaaaaaaga acccttgaat accaagggtt
      601 ctttctcagt ctgataacaa tgattaacga cggatttctt tgatacttgt gaaaagtcat
      661 taaagtattg atataaaagt ttttctcttt ttctgactac actttgacta aagcatagtc
      721 acaacaccta ttttagattc taaaatacct gcacttctgc caaaatctaa ttttctaatg
      781 aatcaaaagc aagcaaaggc tttattcttt cgtttgatgt taaatgccga tatatttttg
      841 aagttgtact atctgtatga cctaaacgat cctttaaaac atcccaactg caatactcag
      901 ctactaaact agccatcgta tgacgagcca gatgagtatg gaaatttttg ttgattccac
      961 atctctctac acagcgctta acgtggtcat ttacatattc acgacgataa ggaactccac
     1021 gcttaccagg atcaagataa acaaataaat aagtctcgtc tacaacaaaa ttgctatttc
     1081 tttttgtttt atttaataca tcaattaatt cgtgcaattt ctccattact aacggtgtga
     1141 caggtactct tctagcagaa ctaacagatt ttgtagtttc aattcgaaaa tctttgcttt
     1201 ttccttttac tgccgtctgc ttataaaata agatttcatt tcgttcaaaa tctatatctt
     1261 gaggttgtaa agcaagtgct tcactcacac gacacccagt ataaaacaaa acatgaaaaa
     1321 gaacagacat gggtaattct tcataaatga tcccataatt taaaaaagtt cgcaattcat
     1381 ctactgttaa aaacttatct tctaaactat taacagactc ttttaaatct tcaactgtta
     1441 actgatactt aggcattttt acaaactcca ttggattttc atttatcaaa ttctttttct
     1501 tacaatattt aaaaatcata tttagaactt gaacaagaga ttgtaaacta tttttagcat
     1561 aaccaacatc aatgccgtca attccttttt cttttaaaat aaaaaggaat ttttgtagtt
     1621 cttctgaaga taaactgctt aattttttat caccaatcca tcgattaagt atttttacct
     1681 gttcttctcg cttatcatat gttgccctct tttgttcgtt tagtgatcga taatattcaa
     1741 accacttttg actaaccaca ttgaatttat cattactagc aattcttttt tgcttatttc
     1801 tgtgttgttt ttccatttca agataagcta gctgagcctc acgcttagaa ttaaaacctc
     1861 gtctcgtagt tcgaaaagcc tgaaagtacc aagtaatttt tcctgttgca gtaatatgtt
     1921 ttttaaaacg actcatattt tccatttgtt tttaccccca attatgaagg aacccaacaa
     1981 tcggaaactc ttgaaaatct ttctatttat aaaataatta tacaatatac agacgaaaaa
     2041 ataaattcta caattctcgt aataaacgaa actgatcaca aaagtattct tcctttcctt
     2101 tttttatcca ctccaaaata tcatctctaa ggtaatgccc tttgatgcca aaccagcatc
     2161 ttggaaaatt atctagtttt ataagacgat ttaaagtact atcacttatt tgaaattgtt
     2221 cttttagatc tttatttgtt aaaactaacg gtaggtcatt tattctcttt actttattga
     2281 tagaatcctc tagctttttg ggattaaata aacaattttc taactctgat gaattatttt
     2341 tattgttatt ctttgacatg attatctctt cccttctatt attaaggatt aatctatcag
     2401 ctgcctttgt caaaagcaca taggaatttc acctctcccc aagtttacgg cgagccttac
     2461 ggaagtatca ttatcccaac ctcaaatcat cgctttttat tgactataaa aattatttta
     2521 gaatatttat cgctccttct ttataataag agatcatggc gtaactaaaa tatgctcctt
     2581 gaagtgttaa cgtactgata gaatatattt atttttcaat gaacaatagg ttttctccct
     2641 aaaagaatcc gctaatctaa agtattagaa gactcttttt ggtagaaaaa gtagaaaggg
     2701 gagtttttag ctagttaact ttaaatttca atatagcttc tattaattta acttctaatt
     2761 gccttagcat atattcatcc acataggtaa taaattgccc cacctcatta aatccatttg
     2821 ttaaacataa cttagctata taattatcat aatgtttgag tatcatcttg atcgaaattg
     2881 gatcttcttc tagagcagat aggataatag atagtggaac taatggatac tgccattttt
     2941 tgggtttatc taccataggt cataccccat tttcaattgt tcaactgcct tcgttcgttg
     3001 ataccagata ccacttgtac tcatattgag aattctaccg atttcagcat cattaaaatc
     3061 ggcaaaataa taaagtagaa taatcttcct tcttatatcc gataactgat caattgctgc
     3121 tgataacttc tgatctgaaa ttaatatctc cattccaaat aagaaataga catcttgttc
     3181 atcaaaatta gtttgtggat acttcccttc atttacatca ttcagtggtt cctcattatc
     3241 ttttattcta gtgtttcgtt ttcgaataga cttagcttcg tttcgtaata cttttttgca
     3301 gtaggcatca aattggtgtt gtatagattt ctcattatag ttttgttgca cgatcaatat
     3361 gctcctttat cccctttcca ctaatacaac aatcagagag tgcctttttt tcgaaaaaac
     3421 taaaaaaaaa caaaaaataa tcatactttt taggtggaat ttcattctca aaaaaaaaaa
     3481 aaacgattag tatcactaat cgtttttgag tattccttgc aaaagccaaa ttacttttat
     3541 agttaaaatt tgatattgat aatcatcctt ctttcggtag tgggtaatca ttttgatctt
     3601 tctattctac ttgatgattt tttagactct ctctttttat aatcaattag gcctaaactt
     3661 cccaacaata gaagaccacc aaagatagta atcatatttg tatcctcttc acctgttttg
     3721 ggtaacattt tcgctttttt agcttgtttc cctacttgtg tagt
//
LOCUS       DAXLPQ010000117         3698 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.121, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000117 DAXLPQ010000000
VERSION     DAXLPQ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.121"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            1093..2016
                     /locus_tag="ACF3UO_002739"
     CDS             1093..2016
                     /locus_tag="ACF3UO_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFD3658666.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            2032..2571
                     /locus_tag="ACF3UO_002740"
     CDS             2032..2571
                     /locus_tag="ACF3UO_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3658667.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
     gene            3256..3429
                     /locus_tag="ACF3UO_002741"
     CDS             3256..3429
                     /locus_tag="ACF3UO_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658668.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNGELKLNSNYYN
                     SPNEELFVKETDK"
BASE COUNT         1383 a          571 c          654 g         1090 t
ORIGIN      
        1 tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct ttttttgtat
       61 tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt gacaagcggt
      121 tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca aaccctttta
      181 gtgagttttg tagaaagtac ctttaaaggt actttcacat tacgaacgat acgtccgtag
      241 gacgtactga aagggtggga cttatgagca aattaatgca aaatttggct agcaaaaaag
      301 ctaaaaaata tatgctaata atcgagcgaa ataaacactt tttcaagtga gcgaatccgc
      361 catgacaaag ctgaagcagt ttatttcagc tttgtcatgg cgtgtgccga cttttttaaa
      421 agtctaggca cacgagcaaa tatctttatc aagctctaat ttgcgtttta agacgtttga
      481 aacgcctaag tatataaata tataagaata ggtttaagag tgcttaaatc gaattttaga
      541 gggcatttag acaattttag ggttgttagg gcttgccctg accgcctgta aggcgtttta
      601 agaacaagat aagggattta tactaggact gtcttaaaat gtcttaaacg aacgctcaga
      661 gcttctcaaa gggttcctta tgaacggctt ttagcaaagg agccggaggc gactgcgcag
      721 tataatgtga gagcagagcg atcacacctt tttagcgaac cgtagggagc aaggtttgga
      781 attggcagtt ttgataaatt cgcgaacctg tttagagaaa aaaggagtga ttttttaggc
      841 gggaaaatta gcctcccctc tttttatatc tctttttata tctcttttta tatctctttt
      901 atgtcggctg tgtccttact ctcccaagca attcagagtt ttttcaagta ggttttctac
      961 gcttttcaag taggttttct acgcttttca agtaggtttt ctacgctttt caagtaggtt
     1021 ttccgacatt attgagtatt tttataaagt atgttacttt tatttcatac tttataaaag
     1081 taggagaagc ttatggcaaa tgaaattgta aaatatgaaa atagattaaa tcatattcct
     1141 ctgagaaaat ttaatagtcg tgaaatgaac ttattttttt caattgcttc acgtgtacgt
     1201 gaaaaaggtg tagatgagat tattttttca tttcacgatt tgaaaaaact aagcggttat
     1261 acagaacgtg gggaacaatt tataaaagat cttagtagca cgtatgacaa attattaagt
     1321 attaatgctt ggaatgatga tggaaatact ttaactaaat ttgttgcttt cacaaaatat
     1381 agcattatac gagataaaca acttgttata atttcagtta atccagaatt taaaggactt
     1441 tttaatcaat taaagaactg gacaagattt aatctagagc aatttactaa tttggatagc
     1501 acatattcaa aaactatgtt tcgattatta aaacaatatc gaactcaagg ctggactgaa
     1561 ttttccaaag aaaaattttt tgatttacta gatattccta aaagttattg gaatagtccg
     1621 tcaaatattg acaaatttat cttaaggcca attaaagaag aactcactcc cttatttaaa
     1681 ggattaacta ttcgtaaaaa atatggtaaa ggtcgaggta aacctgttat cggttatcgt
     1741 tttacttgga aagctgaaat taaccatgct gacgattttt ccaaagggaa acaagaagat
     1801 ttacgtataa aattatttaa tattgatcac aatggagaat taacacgaga agaaaaatgg
     1861 cgcgctaaag atcgaatact aaatcttccc ttaggcactc atgaagctga ttttaaacaa
     1921 caacaacaaa ctgaagaaaa acaggcagaa aaacgagaac tttcaaacaa actcaaacaa
     1981 gatttactag gaaatttaca aaacttattc gattaagctt aaggagtatt tatggcagat
     2041 aaaacaatca aagaacttgc ggaagaatta ggagttagta aaacagcaat taacaaaaaa
     2101 gtttctgaca aaaatcgaaa actttggttt gcaaaaaacg gaaacaagtt tgtgattaac
     2161 gaaaccggtc aaaaagctat aaaatcaatg tttttagtcg ataacgcaaa cttaaatcga
     2221 aaactagttg gcgaaaaatc aaaaaccaaa aaccataaaa acaccaacca agtttccgaa
     2281 ttaaaactcc tttctttcct agaaaaacag ttaaatcgaa aagatataca gctacaagaa
     2341 aaagataatc aaataaaaca aatgcaaaaa ttactcgacc agcaacaaca actcactcta
     2401 caagcgaacc aacaaattga gaacctacaa gaacagctcc atttaactta tacagaagaa
     2461 actccaacaa ccgaatcaac tgccttttct gaaaaaaaag cagacaatac acaaccactt
     2521 attgaaaaaa agtggtggca aatttggaaa tctaatagaa ccaatctcta aaattttcta
     2581 gaagttagtt cggatagtag aggaaaaagt tgtactacct gatggggaga tcactcaaat
     2641 ttttatgaga aagaaaaaat agtttacaac tgtaaacaat caatgtttat agttgtaaac
     2701 tatcaaacta tatggtgact tattgcttaa aataggttga aatctcactc aatttttggt
     2761 ggaaaaacaa aataaattct aatcgatttt gttgaaaaag tcataaaaaa acaaatgtga
     2821 ttttaacaaa atttcaaaaa aatcgtttga aatttcgttt attttttttg agaattttga
     2881 tcatcgtagg gtcattgtag aatcattatg agatcatcgt gggatcatcg aataaagtat
     2941 gggaaaggct tgcggtgctt ggtattaagg gcattctccg cctcccaggt tcttgaccat
     3001 tttctctcaa cgtggtaaaa atcccactta taagagaaaa tggtcaagaa cctaaacggt
     3061 cggcgaagaa aacataccaa gcaccacaag caaaaaaagt tagagtaact tccaaaaaag
     3121 aaaaattttt tagaacaact tttgaaaatt taattttgat ttatatccgt tcaatttaaa
     3181 catttgataa actgaaggct agtatttaaa atgtgtatac aagtggtagc gttaaaaaaa
     3241 gtggaggtat aacctatgtt aaaaaaaact gtgttggtac tgggttctat ttctctagga
     3301 atattaggtt ttagccccat gctattatcc gtaattggaa aaaacaattc caacggagaa
     3361 cttaaattaa attcaaatta ttacaacagt cctaacgaag aattgtttgt aaaagagacg
     3421 gataaataat aaaaaagact gctctttcga gcagccagtt aaaaaataat gagtgtttat
     3481 tcttgaaaaa gcaacgcgct tatgaagcgc taccaaaaat ttatcatatt ttatgaaaaa
     3541 taacacccca gtaaaaaatg actggtaaaa attcacaaag aaacggaaag aagcaactgc
     3601 agaaaatcaa gccttaaaaa gagcttttga cttagaccaa tcgaaaatca caaagtgagc
     3661 ccctgtatcc cttggtagag aggctacttg gcatagta
//
LOCUS       DAXLPQ010000118         3653 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.122, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000118 DAXLPQ010000000
VERSION     DAXLPQ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.122"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..886
                     /locus_tag="ACF3UO_002742"
     CDS             <1..886
                     /locus_tag="ACF3UO_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3658669.1"
                     /translation="SLVDMYVSDYFLKAEASKCITGLYTANEFNHVTPKQLDDKSVVI
                     LCSHGGNTAETVKAGEVAQARGAVTVGLTHNKTADLLKVSDHSFLYEWGDDAKIVNNP
                     MAIILDLTVSLVNVTETFEHYGKFREGMKVIDTVIENGIKQVQDRIKVFADKYKDETM
                     FYILGSGPSYGHAYGFSICSLMEMQWLDSTSVHSGEFFHGPFEVTDKDTNFILLMSIG
                     RTRALDERAKRFLDKYAERVEIVDAKELGLDMISDEVSEFFNPILFYSILSEYRSALA
                     DVRNHDLDVRRYMGKVEY"
     gene            897..1712
                     /locus_tag="ACF3UO_002743"
     CDS             897..1712
                     /locus_tag="ACF3UO_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFD3658670.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGASFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            1780..2490
                     /locus_tag="ACF3UO_002744"
     CDS             1780..2490
                     /locus_tag="ACF3UO_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3658671.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            2526..>3653
                     /locus_tag="ACF3UO_002745"
     CDS             2526..>3653
                     /locus_tag="ACF3UO_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFD3658672.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1208 a          548 c          814 g         1083 t
ORIGIN      
        1 ttcgctggta gatatgtatg tctcagatta ttttcttaaa gccgaagcat cgaagtgtat
       61 tacaggctta tatacagcga acgaatttaa ccatgtaacc ccaaagcaat tagatgataa
      121 atctgttgtc attctatgtt ctcatggagg aaatacagca gaaacggtaa aagcaggaga
      181 agtcgctcaa gctagaggag ctgtgactgt tggtctgact cataataaaa ctgcggattt
      241 attaaaggtt tctgatcata gtttccttta cgaatgggga gatgatgcaa aaatagtcaa
      301 taatcctatg gccatcattc ttgatttaac tgtatctttg gtcaatgtta ccgaaacatt
      361 tgaacattac ggtaaattca gagaaggcat gaaggttatc gataccgtaa ttgaaaatgg
      421 cattaagcag gtgcaggatc gtattaaagt gtttgctgat aagtacaaag atgaaacaat
      481 gttttatatc ttaggtagtg gaccatcata tggacatgct tatggttttt caatttgctc
      541 tttgatggaa atgcaatggc ttgattcaac ttctgttcat tctggagaat tcttccatgg
      601 accttttgaa gtaacagaca aagatacgaa ttttattctc ttgatgagca ttggacgcac
      661 tcgtgcttta gatgaacggg caaaacgatt ccttgataaa tatgcagaaa gagtagaaat
      721 cgttgatgca aaggaactag gattggatat gatatcagat gaagtttctg aattcttcaa
      781 tcccatttta ttctacagta ttctttcaga atatcgttca gctttagcag atgtacgcaa
      841 tcatgattta gatgttcgtc gctatatggg gaaagtggag tactaggagg attaaaatga
      901 aggtattagg cttaggtgat aacgtcgtcg ataaatatga aaatctggga attatgtatc
      961 ctggaggaaa ttcattgaat tttgcagttt ttgcaaaaaa actgggacat gaaagtagct
     1021 ttatgggagt ttttggctca gatgaggagg cagctcatgt tttatcagca ataaaagaaa
     1081 taggactgga caacagtcac tctcgctttg aaaaaggcga gaatggctgt gccagagtga
     1141 agattgatga gggcgaccgg attttccttg gcagcaattc gggaggtgtt actcgtgaat
     1201 acccgattca gcttactgaa gaagacagag aatatttaaa ccagtttgaa ttgattcata
     1261 tgggattata tagccatgtc aatcatctat tagaagagtt acaaaatgtt tctggaaaga
     1321 tttcttatga tttttctgac gactttacgg aagaagaggt tcagcgggca attgataaag
     1381 ttgattttgg cttcttttct atagaagact tttccgatga agaagtaaag cagtttttga
     1441 tgaagcattt ttgtgagcga aatgatgtat tgattgcaac ccgaggagaa aaaacggcta
     1501 ttggttatga tggagcaaag ttttatgaag tgaaccccgt gctagaagaa ccagttgata
     1561 caatggcagc gggagcttct ttcttaacag ctttcctact ttattttctc gaaggggacg
     1621 atatagtcac cgcgatgaaa aaggggaatg aatttgctgg gaagtcttgt ctggttgacg
     1681 gttcgttcgg ctttggtatt cattacgatt gagcttgttt taaattcctg catttgataa
     1741 cctaaagaaa gaaatcccgg taaagtggag gttaaaaaaa tgctggatac aaatgcacaa
     1801 ttaccattgt acttacaatt aaaagaaata ttaaaaaata aaatcaatac aggggagtat
     1861 cccgagaata cgaaaattcc cgctgaatca gagctgatag aaagttatga ggtcagccga
     1921 atcacagtga gaaaagcagt agaagaactg gtagaagaag ggtacctact taaaaaacaa
     1981 gggaaaggaa cttttgtcaa ccggcataaa gtttttcgta aaattgaata tattatgggt
     2041 ttcagtgaga gttgtaaatc taatggtttt acaccgacta gcattgtttt ggaacgcaag
     2101 atcattccag caactgaagg gatggcaaaa aaactcgata tcgctcaagg tgatgatgtt
     2161 ttatatatcc agagaaagcg aatggcggat aacatcccca ttatgttaga aaacaattat
     2221 ttttcttatg aaagatatag tttcttaatg gaggaagagc tgactgattc tttgtatgaa
     2281 gtacttaaag tccaaggtac cttagccatc aatcctgggg aaactgcact tgaaattgtc
     2341 acagctgatg accaaattgc caaaataatg gaagtagctg ttgggacgcc ctttttcttt
     2401 atggatactt taatcaacga tcaaaacaac ataccaattc atgtaggtaa tcaatattac
     2461 ctgggagaag tatatcgttt ttacttatga tttcctgttt ggatttcaag gagtagattt
     2521 tatttatgaa gcaaatattg cggtcaaaaa tgatttttga tggagagcag ccacctttca
     2581 aaggttatat tgtaatcaat gaagggatca ttgaaaaggt ggaaaacaac tggaattaca
     2641 gtgatctatt aaatgaaaac acggaattaa ttgcttatga tgatcaattc gttatgccag
     2701 caattcatga taatcatgta tttttcagtg gttatttggc tatgaatgct ggcatagatt
     2761 taagcgatac atcttcagct aacgaggctg tagagcgtat taaagctgta atgaaccata
     2821 aaaaagcaga tgaaccaatt tatgctcatg gctgggatgc tgccctgtgg aaaactgacc
     2881 catcagaaga gctattgaat gaaataaacc actttggtcc aatcacagcg atcgacaaaa
     2941 atcgcagcca ttgttggatg aatgctattg ctaagcagac ttatggtttt acagaaaaag
     3001 aaaccagtgc tgaaagtcga gtattattaa ttaaggaaat gctagcaaac aaaaagcttt
     3061 tagcagaggt ttacgctgaa tttgaagcat tactgctttc aaaaggtgtt atatcaatga
     3121 aagaaatcgt ttttgatgac gcagaatttc tttctaatat acctcagagg aaaatactta
     3181 gtaacctata tgtgcaggca gtccaagaac ctctacagca tgaacttcta tatgagtata
     3241 aggaaaaagt tttccctgaa aaggtccgct ttggtggagt gaagatcatg gtagatggtg
     3301 ttgttgcgga tagaagtgga gatatttacg gtgtttatca gtcaggagta gcttcacccg
     3361 agattgacta tgaggcaatt aaagcagaag ttgctgcatt caatgaagta gagattcctt
     3421 gctgtttgac aacggaagga gataaagcgg gttataaagc tgcgtcaatt cttgtcgaat
     3481 ttggaaagcg gttacctgaa ggcgttttta attcgattag tgatttggaa atggttactc
     3541 aaaagacagc agaaaaaatg aacgaaggac aagtagtagc agaggtatat ccacaaattc
     3601 tcggcttgaa tcaaacgtta gaagaggctt acatgtcaac tgttataaaa aat
//
LOCUS       DAXLPQ010000119         3638 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.123, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000119 DAXLPQ010000000
VERSION     DAXLPQ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.123"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..330
                     /locus_tag="ACF3UO_002746"
     CDS             <1..330
                     /locus_tag="ACF3UO_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658673.1"
                     /translation="DFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTNIENKGQQP
                     SFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIGKVIQAIY
                     GEKCKFN"
     gene            complement(844..1011)
                     /locus_tag="ACF3UO_002747"
     CDS             complement(844..1011)
                     /locus_tag="ACF3UO_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFD3658674.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(1099..3039)
                     /gene="tet(S)"
                     /locus_tag="ACF3UO_002748"
     CDS             complement(1099..3039)
                     /gene="tet(S)"
                     /locus_tag="ACF3UO_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3658675.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            3024..3149
                     /locus_tag="ACF3UO_002749"
     CDS             3024..3149
                     /locus_tag="ACF3UO_002749"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658676.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
BASE COUNT         1169 a          606 c          563 g         1300 t
ORIGIN      
        1 gatttcaaac cattgggtct tgcgattaaa gaagcccgtc ttagtaaagg attgactcgt
       61 gagcaggtag gatcaatgat ccagattgcg ccacgctatt tgacgaacat tgaaaataaa
      121 ggacaacagc caagttttca tgttgtatat gatttagtga ctttgctaaa tatttctttg
      181 gatggattta ttttagggga agaaaacagt cataaaagct ccaaacgtct tcaagtagaa
      241 gcacagttgg attgtctgga tgaagatgaa ttagtgacga ttgggaaagt gattcaagca
      301 atttacggag aaaaatgtaa atttaactag ttcaataata cacaatggat taattaatac
      361 tatcaggaaa gattgattac aaagatgtaa tgaatttttt ctgatttttg ttaatcataa
      421 atagaaaatg aatttatctt tgttacactt aggaactaga gcgaatgata aatagttctt
      481 tggttactct tatcgctgca aagtacagtt cattttttgt tgttgggaaa attttctgga
      541 tttattgcat atcacttcat ccgactaaaa atttttgatt cccatagcga agttcgtttt
      601 tgttccttag gaaaaacttg actgatatac tagttttgaa atgacgagta actctgtact
      661 tcatcaataa tcaagtattg aattttaatt gtatactttt tatgcttgag ggatgtctac
      721 tgtaatacag ctactgcaaa aaaaatcagt acacttattt tcttataaag gatatcaaga
      781 actaagctca atggtatgca tagaaaagaa aaagccgata aaatgagatt ttgatatctc
      841 gaattatcgg ctctgcgtct ttgcgtctgg ctctgtaatt acagttattc taaacttcgt
      901 tatttcaatt aaaatttctt gtctgcattt aggacaaaat agagggaaat tttttaattc
      961 agtatcttcc ctcattttta aacgggtctt attgccacat atagggcaca gtatccacct
     1021 agtatttaca atatctatat cctcctgttc taattaacaa ctcaatattc attttaaaaa
     1081 tttctcttta gttcactatc aatgtaagtt gattttatta aacatatgcc ttactttgtc
     1141 tattctatta tttggacgac gtggttggaa agcagactta atgttagtaa cctgataacc
     1201 ttttaactct gttaaacaga cactgcgtcc atttgtaaag aaagttaaac tgtttcgata
     1261 ctcttgaata caacgggctg gaatttcacc aatgagaatg acctcgttac cttttaactt
     1321 agtatttaaa atatttgcac aatatttgga agcatcatta tatgctctcg aaagatattc
     1381 ttgtggtaca taaatttcga agctaagata tggctctaat aactctgtac cactctttct
     1441 aaaagcctgc tctagtacaa taggcgcaag cattcggaaa tctgctggcg tactgacagg
     1501 gctgtaatat agaccatact taaaacagat cttacagtct gttaatttcc aaccgtacaa
     1561 tccttgttca cacccatagc gtataccttc cataactgca ttttgaaatg attgatttaa
     1621 ataacctaga gaaaccaggc tctcatactg aatgccacta cccaaaggaa gtggtgttac
     1681 agataaacca atagaagccc agaaaggatt tggaggtact tcgatatcaa tggtaaattc
     1741 agattttttt aatggtcttt ccatataaat gacagttggt tttcttgttt ctatctcaat
     1801 atgatatttt tcttgaatca gagtacaagt tacctccatt tggacctcac ctaaaaaaga
     1861 tagcacaatt tcgtgagtta ctgtatctac ataatattgt agaaggggat cactatcgga
     1921 tatttcaaaa agtgcatcta gtaacttttc tctttgtact gatttacatg gttcaattgt
     1981 tgtttgtaac ataggaagag gattctcaag aatttctcta tgtggtaatc tttttttatc
     2041 tccaagtacg ttatttagtt ttaaaagctc attttttaaa ataataatct caccaggctc
     2101 tgccttatct atctggcgta attctccatt tattgaagta tacatttctg taacttttat
     2161 tttttccttt tctgatatat tgactgagtc tcgcaaatgt agcgttccac tataaagacg
     2221 tacatagaca agccgttgac catcatctga atattctact ttaaaaacat ttccacaaag
     2281 tttatctgaa ttgagttgtg tgggtgaaaa taatttgcta gtaattacct ctataagttg
     2341 tttaattcca atattattct ttgcacttcc gtgataaaca ggatataagg agcaactttg
     2401 aattctttcg ttttcctcct tttcaagttc tgcaatattc aatgttttcc caatggtata
     2461 tttttctaat aaataatcat ttcccacaat tactgtctcc cattgttctg gttcagtata
     2521 atctattaca taaggtttca aatttagatt cacagtctgc ttaattatga tgtcgtcaga
     2581 aagtttgtcc ttaatatctt gataaacatc tggcaaattt attccatttt gatcaatttt
     2641 gttaataaaa aatattatag gtatgttcat ctttctaagt gcatggaata gtatacgagt
     2701 ttgtgactgt actccatctt ttgcagagat tagcaaaata gctccatcca aaacagataa
     2761 tgaacggtat acatctgcca aaaaatccat gtgtccagga gtatctacaa tatttacttt
     2821 aacattttcc cgttgaaaag atgttattgc ggtctgaata gtaatacctc tctggcgttc
     2881 caaaaacata gtatccgttt tcgttgtacc gctatctaca cttcctaact ctttaattgc
     2941 tccgctactg tatagtaagc tttctgtcaa agtagttttt cctgcatcaa catgtgctaa
     3001 gataccgata ttaataattt tcaattttat ttcctccatt caaaagctca aaaagcagaa
     3061 aaaatcccag tgataaatac tcttatcact gggattttaa tacaaaaata gctgtatact
     3121 acacactgat agccacagat gctttatgat aaaatgataa aagtattctt aaactgggca
     3181 caaaaaacca gtccttattt taaataagga tgcttaatta attattcccg ctatctaatt
     3241 gacagtttat ttaagaatac cttgccgcat ttttattatc tccttttgaa tgttatctta
     3301 attctatcat atgatagaat gcttgtaaag ccaaccatat tttttgaacg aaagggaaat
     3361 taatgagaaa ttaatggaag ttagtgtagt agttgaagat aactcttcag aatggctatc
     3421 aaaattcagc gatttaataa cgatttacaa gttcataagg gattctttat tcatccagct
     3481 attatattac ttttcaggtc aataggacaa ctgtccacaa cctttctaca aatatattac
     3541 gtataatttt tgaaatatat actgcttaac aaaatatttt gcagtggttc caatagtttt
     3601 gaattgttaa tattaagttt gacttggaaa atatcatt
//
LOCUS       DAXLPQ010000120         3420 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.124, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000120 DAXLPQ010000000
VERSION     DAXLPQ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.124"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            53..664
                     /locus_tag="ACF3UO_002750"
     CDS             53..664
                     /locus_tag="ACF3UO_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3658677.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            737..1666
                     /locus_tag="ACF3UO_002751"
     CDS             737..1666
                     /locus_tag="ACF3UO_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HFD3658678.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1803..2561
                     /locus_tag="ACF3UO_002752"
                     /pseudo
     CDS             1803..2561
                     /locus_tag="ACF3UO_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
     gene            complement(2609..>3420)
                     /locus_tag="ACF3UO_002753"
     CDS             complement(2609..>3420)
                     /locus_tag="ACF3UO_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFD3658679.1"
                     /translation="MYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAIYMDATYI
                     PLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERGVKNVLLF
                     ITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMVYQASSKK
                     AALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIESFNKQIK
                     KYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE"
BASE COUNT         1123 a          533 c          660 g         1104 t
ORIGIN      
        1 gaagtttata tgaagttata aaatttaatt tatattggaa ggaggaaaat aaatgtattt
       61 tatactacct acactttata gccttttatg tgtaatggca ccatgtatta tttatatggt
      121 atttttttgc aaaaaaaata ccctgaaaca caatatcctg attttgattt ttatgctgta
      181 ctgttggaaa gtttttgaat tgactggtac aggtggacta acagatattt tttatagacc
      241 tgatacaggt aggaaatttt ctctagtaca gggcagtgtt aatcttgtac cattcagtgg
      301 actaaacatt agctttatat taaatatagt aatgtgtgtg cccttaggat tcttactacc
      361 aatcatatgg aaaagttata ggaaaatagt tcctgttttc ttggctgggg ctctattttc
      421 actaattatt gaagtctcac aaattataac tacaagagca acagatattg atgatttaat
      481 agcaaatacc tttggtgcgg ttataggctt tatactgtgg gctgttttaa gtagagtggt
      541 gtccttgaag gacaagtcat ctacagtaga ttatttagaa ccttatattt atatattgat
      601 tggttttacc ggaaaattct tactgtattt tcctttctgg tttgcttttg aagtattatc
      661 ctgataattc catagaaaat aatgagtttg agttgagaaa gaatattctt gtacacaact
      721 ctggaaagga ggaagtatga aaagattctt aaaatggggg cttgttcttt tagcgtcttt
      781 gattgtgatt ctaatgtgta cagcggttgt tatttcttat gtgaatcggc cgtatgcaag
      841 agctgtttat gataggatta aacgcattct tgacaaagat ttttatgacc atctatatct
      901 aggttcttca tttgaaataa taaaccttga tacaatggat attcatagct atatgaaaaa
      961 agaccaagaa gaattacccg cctcattgag caaattattt acgattgatt atgcgcttag
     1021 tgtcctaagt ttagatgaac agattacaat tagtcctact gcacttgaca tgcagaaagc
     1081 tgactcatct actgcacatc ttcaagaagg agatatttta tctgtttatg acattatctg
     1141 tgctatggtc ttaccctcag gaaatgatgc agcttatagt ttggcaattt atacaggtgg
     1201 aaaacttgat cctgatgcaa agaatgatga agaacgctat caaagcttca tgaaaaactt
     1261 agatcgttat ctaagtgagc aaggctataa acatactcat tttactgacg ctgctggcta
     1321 tgactccaat gctacaacat cagcggaaga tttgacaaaa gtagctgcaa agctactaaa
     1381 gaatgataaa tttgcagaaa tagttgccaa ggaaacttat agagcaaaat caattaaggg
     1441 aaatgtttat aactggaata ctacgaatca atttatgcaa caagataata gatactttac
     1501 tgaaggtgta aaaggtgtaa aaactggatc gtttgatggg agatacaatc tatgtgtgta
     1561 ttatacatct agttctgata accactattt acttgtaagt tttggttcag agagtgatag
     1621 taggcgttat gtagatgttc aaaatctatt gcataatctg ccttgaaatt tcgtgccttt
     1681 aagcgcgtat ctaaagtttc tttgaaaagt ttgagaatga agaaagtgag cagtcgaaaa
     1741 acggttgctc acttttttgc cctaaaatcg aaaaaatata aaaaagtcct ttacaacacg
     1801 tctcaggaaa aactgctaag tcaattctaa tatcttgtgg agcaagactt gcaccttttg
     1861 atataagaga gcttagagaa ctaatgagcg aagatgaact agaactcgat aaaattggag
     1921 atagaaaaac tgccttgttt gtaataatat cagatacaga tgatacattt aattttgtag
     1981 tttcaataat gtattctcaa ttatttaatc tactatgtga taaggcagat gatgtgtatg
     2041 gtggaagact tccagttcat gttaggtgtc tacttgatga gtttgcaaat atcggtttga
     2101 ttcctaaatt tgaaaaacta atagcgacaa ttcgttcaag agaaatatcg gcaagtataa
     2161 tactgcaagc acaatctcaa ttaaaagcaa tttataaaga ccatgcagat acaatagttg
     2221 gtaactgtga ctctacactt tttctaggag gaaaagaaaa aacaacagta aaagaattat
     2281 cagaaacctt aggaaaagaa accatagacc tatataacac atcagaaaca agatcaaatc
     2341 aaaaatcttt tggtctaaat tatcaaaaga ctggcaagga acttatgagt caagatgaaa
     2401 taactgtaat ggatggtggt aagtgtattt accagctaag aggagcaaga ccttttctat
     2461 ctgataaatt tgatattaca aagcataaga attacaaatt gttggaagat tatgataaga
     2521 aaaacttgtt tgatgtagaa gagtatttaa aacaaagata gcgtaaaata ttttgtgtaa
     2581 ataactcgtc cttctgcaaa ataatgggtt actcagtaaa cattgaagct aatgtatccg
     2641 tcacttgttg gaagccttta tggcttctat ttaagaattt ttgattgtat gtatcaaaga
     2701 tggatactag gaaacgctct agtgattctt cattttgaaa ctgctctttt ctgtggctgt
     2761 atttcttgat ttgcttatta aaggattcaa tcaagttcgt agagtaaata gtcttgcgta
     2821 tggctaatgg aaaatcatag aaagtgagca ggtaatcgtt cgaaaggatc gattccacca
     2881 tttttggata actggttttc catttttccg caaaagcacc acgtgcttcc aatgccgcct
     2941 ttttagatga cgcttgatac accattttaa aatcatcaca gacttcctta cgatcatcga
     3001 cacgcacttt gtgactgata ttacgggaaa cgtgcacaca gcaatgttga aaacgggctt
     3061 tggggtagaa ccgctgcacg gcccctgcca tcccctttaa gccatccgtg atgaaaagga
     3121 ggacgttttt cacgccacgt tcctggaggt ctattaaaat ctcttcccaa atcgtgatag
     3181 attcagttgg tgcaatcgca tagctcaaca cttcctttga accgtccggg cgaatgccaa
     3241 ctgcgatatg aatggcttcc ttggcgacgg ttttccgctt taaagggata taggttgcgt
     3301 ccatataaat agcggcataa cggtcatgaa gctcacgttc cttaaatgaa gtgacttctt
     3361 ccgtaaatga tttagtcata ttggacatgg tttggggcgt gtagtgatgc ccatacattt
//
LOCUS       DAXLPQ010000121         3390 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.125, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000121 DAXLPQ010000000
VERSION     DAXLPQ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.125"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            647..964
                     /locus_tag="ACF3UO_002754"
     CDS             647..964
                     /locus_tag="ACF3UO_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFD3658680.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="ACF3UO_002755"
     CDS             complement(1055..1420)
                     /locus_tag="ACF3UO_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658681.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="ACF3UO_002756"
     CDS             1628..2110
                     /locus_tag="ACF3UO_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658682.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="ACF3UO_002757"
     CDS             2307..3197
                     /locus_tag="ACF3UO_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFD3658683.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1172 a          519 c          619 g         1080 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac
//
LOCUS       DAXLPQ010000122         3070 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.126, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000122 DAXLPQ010000000
VERSION     DAXLPQ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.126"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(334..696)
                     /locus_tag="ACF3UO_002758"
     CDS             complement(334..696)
                     /locus_tag="ACF3UO_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658684.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="ACF3UO_002759"
     CDS             complement(770..1150)
                     /locus_tag="ACF3UO_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFD3658685.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1232..2407
                     /locus_tag="ACF3UO_002760"
     CDS             1232..2407
                     /locus_tag="ACF3UO_002760"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFD3658686.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2484..3068)
                     /locus_tag="ACF3UO_002761"
     CDS             complement(2484..3068)
                     /locus_tag="ACF3UO_002761"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3658687.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          958 a          587 c          504 g         1021 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat
//
LOCUS       DAXLPQ010000123         2947 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.127, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000123 DAXLPQ010000000
VERSION     DAXLPQ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.127"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(449..865)
                     /locus_tag="ACF3UO_002762"
     CDS             complement(449..865)
                     /locus_tag="ACF3UO_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658688.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGILIGTNSKVYQETKEKI
                     EKQLNPSKRNQPKNRQKETNQTFTSKNFDPTNFLKR"
     gene            complement(867..1148)
                     /locus_tag="ACF3UO_002763"
     CDS             complement(867..1148)
                     /locus_tag="ACF3UO_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658689.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNRYLKVLIEND
                     FDHALMHYKKDQFDLLLEKFIAIQEKNTETLNEYVRTNNQLIETLIGGR"
     gene            1948..2922
                     /locus_tag="ACF3UO_002764"
     CDS             1948..2922
                     /locus_tag="ACF3UO_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3658690.1"
                     /translation="MSKRGTIINEWEKLNRISNRRLNAQTMCTPLKMQWSIDRITIVG
                     TLRENIYYHTPHDVLILDFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYIEILKF
                     QEGKGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKVVPKEIDTWWRLELQ
                     LRRGKATDWHAMVHESLDSFASPHYLPEDVKVTDRMMITALITEHSYWGQIHRNSKYK
                     YRELLKQESQNDELTNHLRETFSESADDLKRELDTWLQGLDVTEVGAE"
BASE COUNT          913 a          438 c          603 g          993 t
ORIGIN      
        1 aaaaaaactt gctgatgaat tgggtgtatc gaaaaatacg gtgcgcaatc aactggtcaa
       61 ttcgggattt gaccttgctc agtataaaga aaaaaatgca gtggtcaatt gaccgaaatt
      121 tatgtctttg ggttttgggg ttttaaaacg aaaaaaaggg ggcgattttc gccccctttg
      181 ctctatgtga aaaatttgtt atacttattt tatccttaaa acataccaat ctttttctta
      241 tttagctgct cgtacgagca gcttttttta cgattatgaa ttcaaatcat gtatttataa
      301 tttttttgtt tttatctttt tttctgttat ttcttctgaa attcgttttt ttcattcaat
      361 tggttactat cttattgtaa atgttgctat taagatggtg atcctaccca aaaaataaac
      421 caggaattta aatctcctgg tttatttttt atctttttag aaaatttgtt gggtcgaaat
      481 ttttagaagt aaatgtttga ttggtttctt tttgacgatt ttttggttga tttcgtttgg
      541 agggattaag ttgtttttca attttttctt tcgtttcttg atacacttta gaatttgtgc
      601 caataagaat acctgtatct tttagatata aatcagcaaa ttctgcaatg atttcggaca
      661 tgatggaaat ttcttttccc atagcattta gtttggcttg gttgctggta gtcgtagtat
      721 tggtatcagg ttcataactc atacataaaa aacgaatggc ttccgagtaa ttgttgatat
      781 ctggatttct ttcgataatg gaatctaaaa cgtccacgtg actgggataa agggtaacgt
      841 gtttttgaac agaagttttt ctcatgttat cttcctccga taagtgtttc aatgagttgg
      901 ttgtttgtac gaacatattc attcagcgtt tcagtatttt tttcttgaat agcgataaat
      961 ttttcgagta ataaatcgaa ttgatctttc ttgtaatgca taagtgcgtg gtcaaaatcg
     1021 ttttcgatta ggacttttaa gtagcgattt cgactccatt ttttgccagt tttatttgtg
     1081 agttcttggc aacgtttgtc tatttttgca ataacctttg aatcgatctt ccgaactaaa
     1141 atgtccatag aaaaactcct ttcgcatttg tgtataattt atgtatatca tacgaatata
     1201 gtatttgtat agctgttttt tgctaaaata ctatacataa gctagccacg atggcgaaaa
     1261 agtgatatca aatttttttc tgagaaacgt gataggcaca gcctatctac ccactttttt
     1321 tagaaagtgg gtacacgttt ccttatgctc tttataaaat ggtgatgtgc gacttttttc
     1381 tgttcgtaaa aataaaaaaa gtttacgaaa atgaaactaa actgaacgat tatgacgggc
     1441 atgtaatcaa gatgaaatga ttttataagc gcgtattttg cgttctaaga cgttttagcg
     1501 ttcatttcgt ttagttatcg gcacaatcgt taaaacacgt aagagaagcg agaatggagc
     1561 ctgtaaggcg actggtagcg aaacggcgtg ttagattgtg caagccgaga actgaatgaa
     1621 atgaagagcg gaagcgtgaa ataatttcgg caggaggagg ctcaaggggt tcggggaatg
     1681 aaattccctg aggtcttttt atttttttaa gaggagtgct ataatcaaag aaaacgagaa
     1741 aaaagagcaa aataaaagcc gaacggtgtt ggaagcaccc ttcggctaat tacggaaact
     1801 actcacctag ttccgtaact caaattcatt atacgaatat ttttaggttt cttcaagcta
     1861 gagatttttg gatatggatt tttagagtta cgtgaactct ggaaattctt tccaaaaatc
     1921 tcttttttct ttgaggagga acaaaatttg agtaaacgtg gcacgatcat aaatgagtgg
     1981 gaaaaactta accgcatatc taacaggcgg ttaaatgcac aaactatgtg caccccctta
     2041 aaaatgcaat ggtcaattga ccgaattacc attgttggta cattaaggga aaatatttat
     2101 tatcacactc cccatgatgt gttgatttta gattttgaac agcttatgcg tctaaacgaa
     2161 ggtaacggat atttaaaagc ggttggaaat aatggctggc aattactaga ccaacatgag
     2221 gaaaatatag cttatattga gattcttaag tttcaagagg gaaaagggcg gattgacttt
     2281 aaccccaata aaattagcca atttctggcg ggctcgatga agaactttat ccatgattta
     2341 tttttagaac cacatttctc acgtgcagat attgcttgtg acattattga cgtgccagat
     2401 gatttcatta cccaatatcg ggtggttgat cctgtttctt tcaaaccaat ttacggtcgg
     2461 tctgggaaac tggaaacagc atattgggga agtcgtgcta gtgaacgaca gattcggatg
     2521 tataacaaaa aattggaaca agaaagaaaa cggaaagttg ttccgaaaga aatcgatact
     2581 tggtggcgac tagaattgca attgcgaagg gggaaagcaa ctgattggca tgcaatggtt
     2641 catgaaagtt tagatagctt tgcaagtcct cactatttgc cagaagatgt gaaagtaact
     2701 gacagaatga tgattactgc tcttataacg gaacatagtt actgggggca aattcataga
     2761 aattcaaaat ataaatatcg tgaattgtta aagcaagaaa gtcaaaatga tgagttgacg
     2821 aatcatttgc gagaaacatt ttcggagtcg gcagatgatt tgaaacgaga attagataca
     2881 tggcttcaag gacttgatgt gacggaagta ggtgctgaat gagtgattcg atagaaaaaa
     2941 tgaccct
//
LOCUS       DAXLPQ010000124         2931 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.128, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000124 DAXLPQ010000000
VERSION     DAXLPQ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.128"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..342
                     /locus_tag="ACF3UO_002765"
     CDS             <1..342
                     /locus_tag="ACF3UO_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HFD3658691.1"
                     /translation="SWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGLHDQ
                     LEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMIRKR
                     LLLEAEKAVKE"
     gene            339..2658
                     /locus_tag="ACF3UO_002766"
                     /pseudo
     CDS             339..2658
                     /locus_tag="ACF3UO_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
     gene            2719..>2931
                     /locus_tag="ACF3UO_002767"
     CDS             2719..>2931
                     /locus_tag="ACF3UO_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658692.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTV"
BASE COUNT         1073 a          437 c          593 g          828 t
ORIGIN      
        1 tcgtgggata tcaatgatat agacatacat tgtacacatg cggacttgga tcttaaggct
       61 ttacaaattg attatgatta tttcctacca gatgaatatg ctagaaatct ctatcatgga
      121 ctgcatgatc aattagaaga aaaaaacgaa gaaaatatgt tttataaaat cgttcaatct
      181 tttgagaatg agacggctaa aaaattgtta attcaatttt acgaagaaca agcaacggat
      241 cgtcttcaag aatatgttga aaagttgatc aaaaatgaag aaatttctga aatgattagg
      301 aaacggctgt tattggaagc tgaaaaggcg gtgaaagaat gatcattgga ggaattttct
      361 ctggcatagc cgactggtgg tcaggtttat tcggagaagg ggatgcagat cccaaaaccg
      421 taacgaaagt cttacaagat tatggtaatt atctgcagta tcaagatgta ttcagttgga
      481 tttgtaatac ttttttatgg ggattgatca aagggttata taatctcaat actttattag
      541 aaaaaacaat ttatcaaagc tttgatttaa aagacttatt gaacgccgct ggtgttaatg
      601 aactatttca aagtttgatt agtaaggtat tggctctttt ttgtgtcgtc acattaattt
      661 atttaggctt gaaatttttt atgagtaaac acccaccgaa agtcaaaaat atcttggtta
      721 atttatttat ggccatgatc ttgatttttg gtggtagttc tttaatcgat gaagggttaa
      781 atatcagtaa aaacttttat ggagacgtca ctgcagcaaa taaagcagat aaaacgggtt
      841 cacctgcttt tcaaattatt caaaataatg tgattgatgt cagtacatta ctagcgactg
      901 acccgaataa agtagaatcc ttaccaacag ataaaagaaa tgctttaaca gcgaaaaatt
      961 tcaaaacagc gaatatcaat gggattatta cacctgatca agctaagaaa atgtctgaat
     1021 caagtgatat tagtacagta caaaaagatc ggttaaaggc attacagtat cgactagagt
     1081 tagacgataa tgggaaagaa atccctgttc aaattagtga tgaaggttta gcaaaatatg
     1141 tgtatacgtc aggctatcgt cgatacatta gtagtccagg gattattttg gctggggaat
     1201 cttctttgtc ggtagcctat ttatttattt tgtttacaat cgttacttgc attattgagc
     1261 tagtatttaa aaaattctat ttagtaattg ccgcgtcaac ggactttgag acaggacaac
     1321 ggatgaaaag tgcgatagaa gatatttctc aatccttctt gttattggcg tttacgattt
     1381 tagaattacg aatctataca ttaatgcttt caggtatcgg tgatttgcat gcggtaggaa
     1441 agatcaatgg attcttgtat gttgttgctt taattgtgct aactattgcg ctattcaaag
     1501 gctctcaatc ggttacgaag attttcggtg ttgatacgag tctgaaaaac ggcagcaatt
     1561 ctcttcttag catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc ggagctaaaa
     1621 accttgcaag tgctggtaag agtggtttaa gccatttaaa tgatattcgt aagaatggat
     1681 ttggccatcg aaaagatatt acccatgata acggggaaga acaatcagac gataaagcta
     1741 caactgtacc taatagtaag aagacagttt ccgaaatgtt cgggaaagcg aaaaatggtg
     1801 tttctaaagc cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa ggaacagttg
     1861 aagatcttac agaaaaagcc aaagacacct tagaagagaa attagacggc acgagagcta
     1921 aagaatttgc tgaagctgtg aagaatccat ccgaagcact agaaaaacaa aaagaaaaag
     1981 cttcagcagt caaagaagga ctaaaagatg cgtatggtga aggacaagtc aatgcagcag
     2041 tgaaggcaaa tacaacaagt gaaaaagaaa atcaagaagg tgcagcgatt ccttcagcca
     2101 aagatcacca agatgagtta cattctaacg aaaattcgat cggagaaaaa gattcagaag
     2161 aaggacaaca tggtcagtta ccaaaaaccg atccagaaca atatcgttat aaatctaaca
     2221 ttaattctga aaacgaaaaa cgcatttcag atttaccaaa acgaaatcaa gaagtacaaa
     2281 cggatgagga ttccatcgat ctgccaaatg ataatggcat cgaagttgga actgaaaaat
     2341 caacgaaaat tggtttgcct aagacacaaa atttaccaat gaaagggtac tgttcaaatg
     2401 aaatcaagtc gtttgcctga aaatggaaat ctgacaactg tttcttacaa tttagctgaa
     2461 agtggtgaaa cagagaatgc gtccgttcaa aatattgtga caaaagaagc tgcacctaag
     2521 ccaatcaata aagttcataa tggatacaga ccagcaaacg tagcatttac tgcaccgaca
     2581 aaaataaatg tgacaagaga aactaaaaac aggaacaatg aattgaaaga acaactattg
     2641 aaggatatca aaccataaaa ggcctattta agggcctttt tctttataaa acaagtttaa
     2701 aatggaaagg agaaaattgt ggaggatatt ttaatagcta cgtttataac tgcactggga
     2761 gcatttttaa cgatatttgt ggtgactatt aaaggattta aagatacgga tagtttacaa
     2821 aaagatcatc agtctatttt agatggtcaa aaaacacata ccgaaagcat tattgtacac
     2881 ctttcagaag gattcactta tttgaaagat gctatgccca cattcacagt a
//
LOCUS       DAXLPQ010000125         2833 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.129, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000125 DAXLPQ010000000
VERSION     DAXLPQ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.129"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..675)
                     /locus_tag="ACF3UO_002768"
     CDS             complement(<1..675)
                     /locus_tag="ACF3UO_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658693.1"
                     /translation="MKSKIILGGLLLSTTAFVSLQSPQITSAESLTNSAEIIVPLNLK
                     VKAHYTNGLPLEAGKEVRLRNLTDGSTEVLKKQVDANGEVIFTEQDGIKKEVNYGIET
                     DGVRNGYTVRYDLGGEKEKDITVNLPGSELPLSLKVKAHYTNGLPLEAGKEVRLRNLT
                     DGSTEVLKKQVDANGEVTFTEQDGIKKEVNYGIETDGVRNGYTVRYDLGGEKEKDITV
                     NLRGSEL"
     gene            complement(1104..2294)
                     /locus_tag="ACF3UO_002769"
     CDS             complement(1104..2294)
                     /locus_tag="ACF3UO_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HFD3658694.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFKGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGAFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
BASE COUNT          791 a          579 c          456 g         1007 t
ORIGIN      
        1 taactcggat cctcgcaaat tcactgttat gtccttctct ttttctccac caagatcgta
       61 tcttactgta tagccatttc ttactccgtc tgtttcgatg ccataattta cttctttttt
      121 aatgccatct tgttcggtaa atgttacctc tccattagcg tctacctgtt tcttaagtac
      181 ttccgttgat ccatctgtta aatttcttaa ccgtacttct tttcccgctt caagtggtaa
      241 tccatttgtg taatgtgctt ttacctttaa actaagtggt aactcggatc ctggcaaatt
      301 cactgttatg tccttctctt tttctccacc aagatcgtat cttactgtat agccatttct
      361 tactccgtct gtttcgatgc cataatttac ttcttttttg atgccatctt gttcggtaaa
      421 tattacctct ccgttagcgt ctacctgttt cttaagtact tccgttgatc catctgttaa
      481 atttcttaac cgtacttctt ttcccgcttc aagtggtaat ccatttgtgt aatgtgcttt
      541 cacctttaaa ttaagcggta ctataatttc tgctgaattt gttaaacttt ctgcactggt
      601 aatttgtggg gattgtagtg aaacgaaagc tgttgtagat agtagcaaac cgccaagaat
      661 tatctttgat ttcataatat cattctcctt aaattctatt tattaagctc aaaaaatagt
      721 ttttatgtta atattctagc tattaaaatt cttaatacta caaaaggaaa ccattgtttt
      781 attgaataga gacatgtccc tatctcctct ctaattagtt tttataaaac gtaactatta
      841 cgttttataa aaacgatttt acaaatttac ttaaaaaatg tcaataaaaa tgaaggttca
      901 ttttttattg aagtgccaaa aatagattaa tataaaattc aactcgattt ttttcagata
      961 gctaaaaatg caacttcagc tttattagct aaaaagttgc attttccccg tataataaat
     1021 tttatagtct aaagcatttc tagaatttga ttgggagcgt caataatttt gtgtaaatga
     1081 ttcttcccta ctgcagattg tttctaattc tcaatcagtt ggcttagcat ttgttcaagt
     1141 tcgccttcgg cctgttgaaa gcctttatga ctgcgaccta ggaatttttg gttgtaagta
     1201 tcaaaagacg agactaagaa acgttccatc gactcttcgt tttggaactg ttccttgcgg
     1261 tggctgtatt tcttgatttg cttattaaag gattcaatca agttcgtaga ataaatactc
     1321 ttgcgtatgg ccaaggggaa atcatagaaa gtgagcaagt gatcgttcga aagaatcgat
     1381 tcaaccactt ttggatagct ggttttccat ttttccgcaa aagcaccacg tgcttccaac
     1441 gccacctctt tagatgaggc ttgatacacc attttaaaat catcacagac ttccttacga
     1501 tcatcgacac gcactttgtg actgatatta cgggaaacgt gtacacaaca atgttgaaaa
     1561 cgagctttgg gatagaaccg actaatcgct cctaccatcc cctttaagcc atccgtgatg
     1621 aacaggagga catttttcaa accgcgctct tgaaggtcca ataaaatttc ctcccaaatc
     1681 gtgatggatt cagtcggtgc aatcgcatag ctcaatactt cctttgatcc gtccgggcga
     1741 atgccaactg cgatatgaat agcttccttg gcgacggttt tccgctttaa cggaatatac
     1801 gttgcgtcca tataaatagc agcataacgg tcatgaagct cccgcccttt aaacgccgtt
     1861 acctcttctg taaatgattt tgttatattg gacatggttt ggggcgtgta gtaatgccca
     1921 tacattttct caatcaagtc tgcgatttcc gacatggtaa taccttttcg gaagaggtga
     1981 atgacggtct cctctaacgt gtcattcgtc cgtctataag caggaacagt ctgttgcttg
     2041 aactcaccat tgcggtcgcg cggaatctgg agatgaagtt ccccatactc ggtcttgacc
     2101 gtacggtcat aggagccgtt acgagaatta cccgtgttaa aaccaatgcg atcatacttt
     2161 tcgtaatcta ggaaagccgt taactccgtt ttgagaagcg tattgactgc tttctccaaa
     2221 tggacacgga ataattcatt caaatcgcct ttgttcgcta gagtctttag aatttctgta
     2281 gtaaaatcgt tcatagggaa gtcctctctt ctgtgaatgt gttgtggtaa ctctattcta
     2341 cagaagggac ttcctttttt ctatttacac aaaatatttt acactctcat ttgattggac
     2401 aacattcata tatatatcaa aaaaacttta acacaactat ataatatttg catatagatc
     2461 atatcccacc gctgttaaga ttgttacatc tagaattagt acctactctg gcactaattt
     2521 cctaaccgtc tcattgaaaa taccacttat acttgaaagc atcttcaatc ttagattgtc
     2581 ctccaaatag tacactcgaa ccattattgc tttactattt aactatttgg tttttatagc
     2641 agttcaagca ctagctatac cgtgctattc caaaaagagc ccttttaaca ttcctctatt
     2701 tcgctagtat taattattta agattataat gaaaaaaaca tatttcttac tatggcttcg
     2761 tatctaattt tgatattatg tagaaaacga atcatattaa tatcgaaaat agatttcctt
     2821 ttgttttgat tta
//
LOCUS       DAXLPQ010000126         2804 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.130, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000126 DAXLPQ010000000
VERSION     DAXLPQ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.130"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..693
                     /locus_tag="ACF3UO_002770"
     CDS             <1..693
                     /locus_tag="ACF3UO_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3658695.1"
                     /translation="TTLREMKVTKETLTTVLNEIFSTPTKEGIQFEIQGMKETREADY
                     YPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTIPLESYPTEQII
                     AEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTRRGKTDPLKIYY
                     EKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVIHVEEKERKLAY
                     QRHQQMNREMER"
     gene            696..1181
                     /gene="ssb"
                     /locus_tag="ACF3UO_002771"
                     /pseudo
     CDS             696..1181
                     /gene="ssb"
                     /locus_tag="ACF3UO_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1226..1459
                     /locus_tag="ACF3UO_002772"
     CDS             1226..1459
                     /locus_tag="ACF3UO_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658696.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(1618..1740)
                     /locus_tag="ACF3UO_002773"
     CDS             complement(1618..1740)
                     /locus_tag="ACF3UO_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFD3658697.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            1895..2154
                     /locus_tag="ACF3UO_002774"
                     /pseudo
     CDS             1895..2154
                     /locus_tag="ACF3UO_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328871.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2602..>2804
                     /locus_tag="ACF3UO_002775"
     CDS             2602..>2804
                     /locus_tag="ACF3UO_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFD3658698.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT          973 a          510 c          568 g          753 t
ORIGIN      
        1 acgactttac gggaaatgaa agtaaccaaa gaaacattaa caacggttct aaacgaaatt
       61 ttttcaacgc cgacgaaaga aggcattcaa tttgagattc aaggaatgaa agaaacgaga
      121 gaagccgatt actatccagg atttagctta cgtgtgctgg cacatttgga aaacatgcgg
      181 ccagatttta aggtagatgt gactacaggt gactcgatct atcctgcaac gatcactcac
      241 agtcataaat tgatgtttga ggatcgaacg attcctttgg aatcctatcc tacagaacaa
      301 attattgctg aaaaattaag tgcaaccttt gattttttaa cagataattc gagaggaaaa
      361 gatttttatg atctctatac tattcctaaa atggagaaga tcgatgagaa gaccttgaaa
      421 gatagtgtga gaaatacatt tacacgtcga ggaaaaactg atccgttaaa gatatactat
      481 gaaaaggata tggatgtact gaaaaatagt cacgagctaa aagatacctg gaagaaatat
      541 caaaaaagca atccttatgc tgcgtcgatc acgtacgatg agacaatgga ttcgattagt
      601 aatttgatgg aaaaagtgat tcacgtcgaa gaaaaagagc gaaaactagc ttatcaaaga
      661 caccaacaga tgaatagaga aatggagaga taaagatgat taataatgtg acattagtag
      721 gacgcttaac caaagatcct gatttacgtt ataccgcaag tggtactgca gtagcgactt
      781 ttaccctagc cgtcaaccga aatttcacga atcaaaacgg caattgagaa gccgatttta
      841 ttaactgcgt gatttggcgc aaaccagcag aaacaatggc gacattagct aaaaaaggta
      901 gcttgattgg tgtagttggg cggattcaaa cgcggactta cgacaaccag caaggacaac
      961 gtgtatatgt gactgaagtt gtagcagata actttcaact attagaaagt aaagcagcga
     1021 cagagagccg tgcgcacgct gatcaatcgt ccaccagtcc aagcaccgcc acctttgaac
     1081 aacggaatac agcgacgcct aacaacaatg gattgaacgc ttcacagaat ccatttggtg
     1141 gacaatcaat cgatattagc gatgatgatc taccgtttta gtttgagaaa gaaggagtaa
     1201 gcatggcaaa aaaattagtc tgacgatgga tctattgata cccgtaattg catttataga
     1261 cgggatttct ttgggcgtca ctgaaaatcc tttggtaaat agaattgcga aaggatcact
     1321 atttcttgta ttcgtgtatc ttgtctgttc ttatctttta aaaagagcag gaaaggataa
     1381 ttccttttgg cgattgacta aagtcacagt agcagcgaca gctgttatac ttacggctat
     1441 tctaccgctt tatatgtaga gttaacggga aatcgttgaa cttcttgcga aatattgcta
     1501 taatgaacat gaaaaagagg agttgcgcta acaacccctc attaacagca ccgattaaag
     1561 aacggtggca gaatattagt tatttggaaa taaccgctga cctgctaaag tagacggtta
     1621 tttctttttg tcatttttaa gcatatttac aatcaaacta atcaaagcaa tggtaaacat
     1681 accaaaacca agaatggttt gaattgtctc atatgcggac aaaaggctta ctcctttcat
     1741 agattttagc acttacattc ataagcacca ccacctttcc agaagtcgcc accgtcttca
     1801 aactttactg tcttgactat tatagcatat ctaaaatcga ataaaaattc tcaattttag
     1861 ctgtttttgc tataatttta gcgaggtgat cgtgatggaa caatatattg gtttactcga
     1921 taaattaggg tgatcaagac acagccattg cttgtgcgat ttacattacg cacgagtcat
     1981 gaaccaatca attgtgtagt ggccaatata gaaatagcgg ataaattgct gattttggaa
     2041 gaaggcaagt atactatttc agtgacaggt cacttcaata aacgaaatca actagtcatt
     2101 gaatcaatgc aaattagaaa ccctgatcat tttacgagat taatgggcat ataaataaaa
     2161 gaagagctgc agtcctaaat gaggattgca gctctttttg ttttacatag aaacaagaaa
     2221 aatgaaaagg cctttttagg aaggcgcaag cgccttctca attgaaaaac ctctctctca
     2281 ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac gttgcacgtt cactaagata
     2341 aggggtcttg caaagcaaga caaaatagaa aaaacttcct ctcaccaaaa ggttcgttcc
     2401 tgttcgctat ctctttattg atttgccaga ccggcaacaa gttgcctttt atcaccaaaa
     2461 agcgacaagg acaagggtaa atggcacgct gcacgccctt gtccttgtcg cttttagttg
     2521 attcattctg gccaacaaat caataaagaa agaactaacg aaaggaagta aaacctttcc
     2581 taagaggagg cagaatcaat catgcgaaag aaatttgatt attggggtgt tcccttcagc
     2641 gaattattcc caaactatca tgcaccatat actgtcgaat gcgattgtgg agaaagagcg
     2701 aaatgtatca aaagctattg tttgtatcaa tgtccaacat gcgggaaaaa atataccttg
     2761 tcttatggcg attatatttt gattgatgag aaaggaaaga aacg
//
LOCUS       DAXLPQ010000127         2663 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.131, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000127 DAXLPQ010000000
VERSION     DAXLPQ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.131"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            2..793
                     /locus_tag="ACF3UO_002776"
     CDS             2..793
                     /locus_tag="ACF3UO_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFD3658699.1"
                     /translation="MPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFDGFSP
                     FPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYFGSIL
                     GINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISFVLSM
                     IGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILLQLSF
                     IGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            863..1603
                     /locus_tag="ACF3UO_002777"
     CDS             863..1603
                     /locus_tag="ACF3UO_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3658700.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            1614..2618
                     /locus_tag="ACF3UO_002778"
     CDS             1614..2618
                     /locus_tag="ACF3UO_002778"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFD3658701.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT          839 a          438 c          544 g          842 t
ORIGIN      
        1 aatacctatt tctgaatatc ggaaaaaagc acgagtttct ttggaaaatc aatggggaat
       61 caatacttgg cttgttttct tatctataat atttacgagc gtcatccaga acttttttga
      121 cggtttcagt ccttttccgg aagaaagcat gcagcagcac ttattgagtt ttctagtcga
      181 taatttactt ttattcgcat tcaactatgc attgttttac attgcgctag tagttgtacg
      241 gggtggcaga ccaaaaagta accttttatt ttcagttttc caaagaaagt attttggttc
      301 gatacttggc atcaatttga tcaattcagt catcaactgg ctactcaaca gtttaatctt
      361 tctgcccatg tttttaatca gcggagtgag tacttatatg cagctgcttt tcagttcaaa
      421 tgcggtacct acgggtgtca tgccagaaga ttttcttgat atcagctttg ttttatcgat
      481 gatagggatg atttttgttt cagcactcat catgagtatt gttggcggtt tattccaatt
      541 tgctgcatgg acaaagttcg actatcctga tttgtcggtt attcaatgtt tgaaatatgg
      601 ctggttttta ttgaaagata gaattggtac gtatattttg ttgcagctgt cttttatcgg
      661 ctggtatttg ctaggagcaa tcgctttgtt catcggtctt ttgtgggtca ttgtttatgt
      721 gaatgtgtca gttgcagaat tttatgaaca agcacggatt gaaaaaggag gtccagacgc
      781 ctattttact tagcatgtaa gcagtttatt catcaaaaaa ataacttttg tggtaggata
      841 aatctttgag ggggaatgta cgatgaaatt aactgtttta ggatgcttag gagcgtatcc
      901 ttataaaaat caagggacaa caggttattt gcttcaatct gacgggttca atttgttgat
      961 cgatgcaggt agtgctacgc tgatcaaatt acaagaacac cttgatccac ttgatctaga
     1021 tgctgtgatc cttagccatt atcatcatga tcatattgct gaccttggtg tattacagta
     1081 ttactggcaa cttcatccta agagaaatcc ggagacattg ctttcaattt atggacacac
     1141 aaaagattcc attcactttg aagaattgac gttggaaaat gtctcaaaag gacatcctta
     1201 ttttgaagct gaagaattaa aaattggtcc ttttctgatt acttttatgg aaacaatcca
     1261 tccagtagta tgttacgcca tgcgtatcgt agaagaaaca acggggaaag tattcgtatt
     1321 tacaggtgat tcaggttatt tggaaagttt cgctgatttt gcgaaagatg ctgatttgtt
     1381 tctagcagat acctatcttt ttgaaggaaa tgaacatcat catgcccatt tcacttcaaa
     1441 agaagctgga gaacttgcga aatcagctaa cgtaaagaaa cttgtactta cacacctacc
     1501 tcagtttggt gatttagaac aattgaaaaa tgaagcgcaa aaggcagcag gcaaagggat
     1561 tgatatagaa cttgctgcag ttgacaaagt gtttaacatt taggaggaag aacatgattt
     1621 ttgtaccaaa tgaaaaccac gacccaagaa tcaatttagc aattgaacaa tatttgctgc
     1681 aagaaatgcc tttagatgaa cctattttgc tcttttatat caatgaacct tcaatcatca
     1741 tcggcagaaa ccaaaatacg cttgaagaaa tcaatcgaga ttatgtggaa gaaaatggca
     1801 ttcatgttgt ccgtcgctta agtggaggcg gagctgtcta ccatgatttt ggaaacctga
     1861 actttagttt tatcatgcct gatgatgggg attcattccg tgactttgcg aaagtaacac
     1921 agccaatcat ccaagcactt catgaattgg gtgttgctgg ggcggaattg aaaggccgaa
     1981 atgatctagt cattgatggc atgaaatttt ctggcaacgc gatgtatgct accaacggtc
     2041 ggatgtttgc tcatggaaca attatgttcg actctgatat caatgaagta gtcaatgcat
     2101 taaaagtaaa aaaagacaaa atcgaatcaa aaggaatcaa atcgatccgt tctcgtgtaa
     2161 cgaatatcaa accatttctt ccagaagaaa agcaaaaaat gacaacagaa gaatttcgtc
     2221 aagaaatctt gttgaaaatt ttcggcgtag agtcagtaga agaagtaaaa acgtacgaat
     2281 tgactgatga agattggaaa aaaatcaatc gaatctctga ggaatattat cgaaattggg
     2341 attggaatta cgggaagtct ccagatttca atttctctcg ccaaaaacgt ttttctatcg
     2401 gttcgattga agtccatttg aatgtctcag aaggaatgat caaagaagca aaaatctttg
     2461 gcgatttctt cggactagga gatatctctg acgtggaaaa aaaattggtt ggacagaaat
     2521 atgataaagc atctctatca aaaatagtca gccaaattga tgtgaagaaa tattttggtg
     2581 cgatagaacc agaagaattg cttaccttac tttattgaaa ataaaaaata gcggaatcca
     2641 catatatgga ttccgctatt ttt
//
LOCUS       DAXLPQ010000128         2600 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.132, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000128 DAXLPQ010000000
VERSION     DAXLPQ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.132"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            47..484
                     /locus_tag="ACF3UO_002779"
     CDS             47..484
                     /locus_tag="ACF3UO_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658702.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            477..1172
                     /locus_tag="ACF3UO_002780"
     CDS             477..1172
                     /locus_tag="ACF3UO_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658703.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            1337..1537
                     /locus_tag="ACF3UO_002781"
     CDS             1337..1537
                     /locus_tag="ACF3UO_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658704.1"
                     /translation="MNKIIPLLLVLFVGEILMRLSAAVHLNLAVFLVILMFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            1553..1732
                     /locus_tag="ACF3UO_002782"
                     /pseudo
     CDS             1553..1732
                     /locus_tag="ACF3UO_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1794..1978
                     /locus_tag="ACF3UO_002783"
                     /pseudo
     CDS             1794..1978
                     /locus_tag="ACF3UO_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            2012..2443
                     /locus_tag="ACF3UO_002784"
     CDS             2012..2443
                     /locus_tag="ACF3UO_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFD3658705.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          937 a          404 c          535 g          724 t
ORIGIN      
        1 cgaatattgg ttaaccaaat tagagaacta aaaaggagaa aaaaatatgg ctcaaaatta
       61 ctatgacgaa tttgtcaaat tacctttgga taaaatggca caaaaaatgg aggatatgac
      121 attcctatac aatgagacac gtgttccaaa aaaacattat aaggaaagat tgtcggtagc
      181 tgtggaagaa atgattgaat cgggtgtcga aatgaatctc attgcgacct actatcgaac
      241 gcttgaagaa ctgaaaaagc aaaatggaca atggtttttc caagccttac tatgcttgga
      301 agcaggcgtc aagccaaaca ctatcaaacc ttctgaatac caagctttag aactaacgta
      361 tgggaaattt gtcgaaacga aaaaagccaa gactgtttca agtgaatggt tggactactt
      421 agaaaatgtc aacaagtatg gcgcatgtta catcatgaaa aaggaggaca acgaaaatga
      481 ataaggtgat ttatcaacta acaacggaag atgtgtcaca ctttttaaca aacaaagaac
      541 atttgaatga agtaatcaga cggattcaaa aagactttag ttgtatggaa gaaatgaagt
      601 actttattca aagagtcgaa gaacaattgt atttggaaag tgaaacgagt caaacgaagg
      661 ttacagtcag caataattat ttagacgtgt ataaacgtcg tcctgacaca ttaaaaaaag
      721 gagcggagct tctacgacta gaaacagaaa aatatatcat gaatgtttac ctagaaagga
      781 gtgaactggt cgaaaacttt gtcagctaca cgatttgcag gaaacactat tactcagaat
      841 cagaatatta ttcaattttt gagagcatgg aattaatgga agagctaaac agcaaagatg
      901 cgacggtaga cgattattac cttgtattta ctaaattttt gacgtgtggg acggaatcta
      961 tcgtgttaat gggaatggat tatgaactcg ctgtacccga agtatttttg agggaatatg
     1021 tagaagaagt agataaccca ggcgacgact ggtacacgac tttaactgat tttttagata
     1081 cctacactta cgacgataca gaagaaatcc aaaatgaact tgaccgtaaa cgaatgccat
     1141 atcaacgatt tgaaaggaaa aaaggtcaat aaccatttat accgaaaagt gagaatgtgt
     1201 gaaataaaaa caaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgctc
     1261 caaccgcccc cgccgcttag gtggtgcgaa ataagcgagc aaagcccgaa aacctaagag
     1321 aaagaaggag atttatatga acaaaattat tcccttatta ttagtcctat ttgttggaga
     1381 aatacttatg cgacttagtg cagctgtaca tttaaacctc gcagtatttt tggtaatact
     1441 aatgttttgt ttgatctttt ggcgatttgt attagccctc gtaagtctac tattcaagat
     1501 gattgcagcc atatttttca taggattatt tcgatgaaag gagagagtac caatgccaat
     1561 tgcaatagga aataaacggt tacccgtgac gttggatgaa aagagacaaa aagaattgca
     1621 gtaaccaaag cagaagtacg gcaaaagtga atccaggatt atgtgtattg cgttagattt
     1681 attgattgcg caagaaaaag caggatttga cataccagca ctcaaaaagt gatcgcactt
     1741 tgcgcacgtg ttaatacgtg ttataattat tttgtaagga ggtatagtgc acaatgccac
     1801 ttacgggaaa agaaatgctt aagttattga aaaaaatggc tgggttgagc gaaggcaaga
     1861 gggatttcat catcatcttt ataaggatgg tgttagaatc actgttcctg ttcatgccaa
     1921 tcaagatctt ggccgaggac ttgagcgaaa aattttaaag gatgcgggat tgaaataatc
     1981 tcgcattcga ttaaagaaag gattgactga aatgttaagt gagcctttag caaaaaccta
     2041 tcctgctatt tttagcccag aagaaggtgg tgggtacttt attgaatttc ctgatgttca
     2101 aggtgcttac acaggaatta acgaagacga tatatcttat ggaattgcta tggcacaaga
     2161 ggtgttaggt atggttttag cagattatat tgagcatgaa gatctacttc cagaaccaac
     2221 accaatcaat aagatttctg ttgaagatga ttcttttact actttaattc gtgtagatgt
     2281 tgccaaatat ttgaaagaca cagaacttgt caaaaaaacc ttaacaattc ctcaatgggc
     2341 ggataagcta ggcaaaaggg ctggcataaa tttttcagtc cttctaacag aatcaattgc
     2401 agataaagca gataacattc ttcgttctgg aagaaataat tagaactcaa aagggtcaga
     2461 aacttaaaaa tctttggctt ctttttttac tacaaagatg gcttctttaa attatttgcc
     2521 tgattgattt aaaaaaattg cgcaaagact acgagctaat taagttgctc gtggtctttt
     2581 tttatgaaaa ctttttagat
//
LOCUS       DAXLPQ010000129         2566 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.135, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000129 DAXLPQ010000000
VERSION     DAXLPQ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.135"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(53..910)
                     /locus_tag="ACF3UO_002785"
     CDS             complement(53..910)
                     /locus_tag="ACF3UO_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3658706.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(1195..1482)
                     /locus_tag="ACF3UO_002786"
     CDS             complement(1195..1482)
                     /locus_tag="ACF3UO_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3658707.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKIIPVLLCGTHEKFYEQLKKLI"
     gene            complement(1472..1801)
                     /locus_tag="ACF3UO_002787"
     CDS             complement(1472..1801)
                     /locus_tag="ACF3UO_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3658708.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(1878..2150)
                     /locus_tag="ACF3UO_002788"
     CDS             complement(1878..2150)
                     /locus_tag="ACF3UO_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3658709.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(2150..2413)
                     /locus_tag="ACF3UO_002789"
     CDS             complement(2150..2413)
                     /locus_tag="ACF3UO_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3658710.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT          772 a          517 c          337 g          940 t
ORIGIN      
        1 tggcgagtcc tttattgttc ccaaaaatat caagtccttt gatgtcagcc aattactcca
       61 cctccgcata ccaattctcg tgttcttcca attctttcaa aatactgata aataattcgt
      121 ggcttttgcg atcccattgt tttaagagac ctttctttgt cttctccatc gtaatacctg
      181 atccgtcgta tcgttttaag cgcgcatttt tgagtacaac atttttaatc aaatgttccc
      241 cataaatctc ttgggcttgt ttatacattt cctgatctac tgcgtcaccg ctttccaaca
      301 tgaaaggaat aacaccagca acatataaat ttgtatcaaa ttctttcaca aaaaagtcca
      361 tatactcaag atattgcatc gcatttctca tcgattttac ttgggtctgt aagacgacga
      421 ttgcccagtc cgcaatgtac atcgcggatt tactatatac agaaatagaa ggtgggacat
      481 ctaaatagat gacgtcaaac tcatcaaata atggttctag cttttctttc atatatttga
      541 attgggataa tgaatcatta tattggtctt tgatccaatc atcatacatt tcaaaggaca
      601 tgtctgctgg aagtatatag aggttattga ttactttata gacagcctct ttaggtggaa
      661 gattgtttat caacacgtca gtcacagtat tttcgtaaac aatcggttca ccttctccgc
      721 ctccttcttc gttagtgaag ttcatatgcg ttaagttcat cacatcagaa gtatttcctt
      781 gcatatccaa gtcaattatc aaggttcttt ttccttcatt aactgctgat tcaaacccta
      841 acatttgcgc gcacgtactt ttacctacgc cacctttaaa attaccgatt acatatttct
      901 tcgctaccac gttcctacct cttttctttt agcaatattc atttgatact attataacat
      961 atttattttt agttactacc aaaaaaagat atatatgtac taccttataa ttaataagga
     1021 aaaggtagta cataaataag gaaaagctga aatatattga tttatagctt tcctcaaagt
     1081 aatgacgtta tttaatttat cgagaagcag agaatactcg cgactttagt catgtagacg
     1141 aatcagattt tcgataaaaa agaagccgtc cttcttaaga acgacaacaa atcactagat
     1201 taattttttc aactgttcat aaaatttttc atgcgttcca cataacaata ctggaataat
     1261 cttgttttct ataatctcgt aagctactct atatgttgtg cccgcatatt taaacccact
     1321 agaccaaata cctgataaat ccccagtttt ttgttcaccc ttatatggat caatcgcaat
     1381 ttcatcataa attaaattca aaaatttttc tttcaatggc ttctctttta gcttttttaa
     1441 atacttaatg acatgttttg aaggaacgat ttcataagcc aatttctgtt gccaactcct
     1501 ctttagtcat tactttagaa ttagtaagtg tatcttcagc aatatctcta aaggaagaat
     1561 gcattttgtt ttttctattc ttaaattcta caagaatctc atctttatcg tagccttctg
     1621 caattatatc agacaaaata tcttcgctaa aatcataaaa ttctttttgt ggttcaacaa
     1681 attcataaag aataccattc tctaccaact ttgcttcaac ttcgactcca ttaggaacat
     1741 taaaatcttt aggtactgtc aacatgattg aattgccttg ttttcttgtt tttgtaatca
     1801 tttaaatccc tcatttctaa cagtatgtaa ttacttagta aatacattat accacgagat
     1861 aatgtattta caagtaatta ctgtgactcg taatgcgtcc ttgctgaata aatttcaacc
     1921 acgtgttcat cttcatctac cttataaaca acccggtgtt gtctattcaa tcttctagaa
     1981 tacctacctt catgtgtagg ttttaacttc tcaaatgatt gggtagggag atagggatct
     2041 tcctttaaag tctgaataac cttctcaaat tgaggtttca aattagactg tttgattttc
     2101 tttaaatcag ctttagccga gtttttaatc atcacagaat agttattcat tataagttat
     2161 cccaatcaat ttcatcaaca ttagtaaatc cactatcatc tttttctcgc ttacgaacaa
     2221 cacccaaagt gcctatttgc tcaagtaata gcgtttcttt gattgctttc caatcatcca
     2281 aaccaataag caccgcatta ttttcactgc gctcactaat gatttcaatt tccgtatgat
     2341 tctcatttac atctttcaac aacttataaa aatttttccg tgctgagcta ggatttaaga
     2401 ctgtttttgc catatctact ccccctctaa tttatatctc cattctaacg tacttaatta
     2461 agtacgtaaa ttcgattgtt ttgtttaaat tggagtacca aaacagcatt gtaaagtgtt
     2521 atccgtttcc tttatacccg tggtgctagt taattttttc ctagag
//
LOCUS       DAXLPQ010000130         2492 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.136, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000130 DAXLPQ010000000
VERSION     DAXLPQ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.136"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(147..1523)
                     /gene="tet(L)"
                     /locus_tag="ACF3UO_002790"
     CDS             complement(147..1523)
                     /gene="tet(L)"
                     /locus_tag="ACF3UO_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFD3658711.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            complement(1557..1610)
                     /locus_tag="ACF3UO_002791"
                     /pseudo
     CDS             complement(1557..1610)
                     /locus_tag="ACF3UO_002791"
                     /inference="COORDINATES: protein motif:HMM:NF019662.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            complement(1717..>2492)
                     /locus_tag="ACF3UO_002792"
     CDS             complement(1717..>2492)
                     /locus_tag="ACF3UO_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658712.1"
                     /translation="THEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLK
                     NAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYG
                     CEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF
                     KIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR
                     SVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
BASE COUNT          865 a          502 c          383 g          742 t
ORIGIN      
        1 ccactcaaaa taaaaaagat acaagagagg tctctcgtat cttttattca gcaatcgcgc
       61 cctttaatgg aacaaaaaga tttgaattcc tgttataaaa aaaggatcaa ttttgaactc
      121 tctcccaaag ttgatccctt aacgatttag aaatcccttt gagaatgttt atatacattc
      181 aaggtaacca gccaactaat gacaatgatt cctgaaaaaa gtaataacaa attactatac
      241 agataagttg actgatcaac ttccataggt aacaaccttt gatcaagtaa gggtatggat
      301 aataaaccac ctacaattgc aatacctgtt ccctctgata aaaagctggt aaagttaagc
      361 aaactcattc cagcaccagc ttcctgctgt ttcaagctac ttgaaacaat tgttgatata
      421 actgttttgg tgaacgaaag cccacctaaa acaaatacga ttataattgt catgaaccat
      481 gatgttgttt ctaaaagaaa ggaagcagtt aaaaagctaa cagaaagaaa tgtaactccg
      541 atgtttaaca cgtataaagg acctcttcta tcaacaagta tcccaccaat gtagccgaaa
      601 ataatgacac tcattgttcc agggaaaata attacacttc cgatttcggc agtacttagc
      661 tggtgaacat ctttcatcat ataaggaacc atagagacaa accctgctac tgttccaaat
      721 ataattcccc cacaaagaac tccaatcata aaaggtatat ttttccctaa tccgggatca
      781 acaaaaggat ctgttacttt cctgatatgt tttacaaata tcaggaatga cagcacgcta
      841 acgataagaa aagaaatgct atatgatgtt gtaaacaaca taaaaaatac aatgcctaca
      901 gacattagta taattccttt gatatcaaaa tgacctttta tccttacttc tttctttaat
      961 aatttcataa gaaacggaac agtgataatt gttatcatag gaatgagtag aagataggac
     1021 caatgaatat aatgggctat cattccacca atcgctggac cgactccttc tcccatggct
     1081 actatcgatc caataagacc aaatgcttta cccctatttt cctttggaat atagcgcgca
     1141 actacaacca ttacgagtgc tggaaatgca gctgcaccag ccccttgaat aaaacgagcc
     1201 ataataagta aggaaaagaa agaatggcca acaaacccaa ttaccgaccc gaaacaattt
     1261 attataattc caaataggag taaccttttg atgcctaatt gatcagatag ctttccatat
     1321 acagctgttc caatggaaaa ggttaacata aaggctgtgt tcacccagtt tgtactcgca
     1381 ggtggtttat taaaatcatt tgcaatatca ggtaatgaga cgttcaaaac catttcattt
     1441 aatacgctaa aaaaagataa aatgcaaagc caaattaaaa tttggttgtg tcgtaaattc
     1501 gattgtgaat aggatgtatt cacatttcac cctccaataa tgagggcaga cgtagtttat
     1561 agggttaatg atacgcttcc ctcttttaat tgaaccctgt tacattcatt tcacttcata
     1621 attaattcct cctttacact ttaattcaaa tctttattaa aaaatatttc atcttattta
     1681 acaagaaacc atatttatat aacaacataa aatacactaa gttattttat tgaacatata
     1741 tcgtacttta tctatccgac tatttggacg acggggctgg caaacaggtt caccggtagt
     1801 aacatggtac ccttttaact ctgttaaaca aacactacgt ccatttgtaa agaaagttaa
     1861 atcactacga tattcttgaa tacaccgagc agggatttct ccactaagaa tgacctcatt
     1921 atttttcaat tgagtgtcta cgatgttcgc acaatattta ggagcatcgt tgtatgctcg
     1981 tgaaagatat tcctgtggcg cataaatttt aaaactaaga tatggctcta acaattctgt
     2041 tccagctttt tttaagactt gttccaatac aataggagca agcatccgaa aatctgctgg
     2101 ggtactaaca gggctatagt ataagccata cttaaaacag attttacaat ccgtcacatt
     2161 ccaaccatat aatccttgtt cgcaaccata gcgtatccct tccataactg cattttgaaa
     2221 tgattgattt aagtatccaa gagaaaccga gctctcatac tgcattccac ttcccaacgg
     2281 aagcggtgat acagataaac caatggaagc ccagaaagga tttggcggca cttcgatgtg
     2341 aatggtatat tctgcatttt ttaacggtct ctccatataa atgactgtag gctcttttag
     2401 ttctatctcc acatgatact tttcttgcaa cagtgcacta atcacttcca tttgtacttt
     2461 ccctaagaaa gaaagtataa tttcatgtgt cg
//
LOCUS       DAXLPQ010000131         2486 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.137, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000131 DAXLPQ010000000
VERSION     DAXLPQ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.137"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..302)
                     /locus_tag="ACF3UO_002793"
     CDS             complement(<1..302)
                     /locus_tag="ACF3UO_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFD3658713.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKYV"
     gene            395..744
                     /locus_tag="ACF3UO_002794"
                     /pseudo
     CDS             395..744
                     /locus_tag="ACF3UO_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1016..1306)
                     /locus_tag="ACF3UO_002795"
     CDS             complement(1016..1306)
                     /locus_tag="ACF3UO_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658714.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1514..2206)
                     /locus_tag="ACF3UO_002796"
     CDS             complement(1514..2206)
                     /locus_tag="ACF3UO_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3658715.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          735 a          459 c          349 g          943 t
ORIGIN      
        1 acatacttgc aaagtaatac tacaattcct aacataatcg tagaatttaa taatttccat
       61 agcataaagt gtttagaaaa gaacattaag aatagttcta taataattct tgaactccat
      121 gtcttataat gttctatcga agcacccaaa tagccaagtt catctaatct acttgcataa
      181 actacgtcat ccgctctcat agtcggcata tacatattaa agagtaaaaa gataccccaa
      241 atccctatta gtaacaagat cagttctttg ttattcgtta tttttctatt atgtttgttc
      301 atttttatac tccttcttat atttcctaat agagtataac atagctttaa gcattactta
      361 aagataactt aaaagttatc ttttaaatac ttaattgtta aataccttat ttgatgcaaa
      421 agaaatctac gatagtcaac aaaaaaattt tcattatatc cagaaaaatt tttcttagtt
      481 aaggacctat ggattgcagt aatgcagaat tcgtcgaata aactgccaaa gacatacaat
      541 catattgctt ttaaaattga cgaacaagat atagattcgt ttgtctcaaa aatccaaatg
      601 ttaggtttaa ctgtcgaacc aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac
      661 ttttacgact atgataatca cctcttcgag ttacataccg gtactctcca ggaacgttta
      721 aaatcctaca attccactac ctgagactag taatgactag tctcttttta tggcctctga
      781 tccccccatt gagcgaatac taatagggct tcgaattgat ctgttcaatc tttaagcaat
      841 atccctcaaa tgagtttgga aagtttagtg attcatcaca aatacttaaa tacatgtagt
      901 tatatataga ttgaggttct tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg
      961 catccatctt tccaaaacaa gcggctagga catttttgtc tcagccgctt gttttctagt
     1021 ttattctttc atcttgtcgg accttttttc ttgggtatag acttttctca tattctacca
     1081 caattttggg tttccctaac acatgatagg atctcacaac aaattgcttt ctattattat
     1141 aataacctgt aacgactaac ttcatccctt cgtctacttc agctaggaag ttcaaactat
     1201 gggaagcaat caaacaattg accccattta aactgaaacg gatcaacggt ctggcactaa
     1261 cttgcaaagt acggatctta tctactgttc catatttttt ctccataacc ttcacctcaa
     1321 taccattata cgaacataca ttccctttgt aaagaagaaa ctctgtttta tctttttgac
     1381 tttttgtcta ttacctttct taaaatcata ttggcacttc ctgcgaagat gaaggacatg
     1441 tactaaaaaa aagaggcagc agtatagatt actgttgctt ctttactaat ttaggtttac
     1501 ttgttaagaa agattattta cgcaaatgtt cttcaacaat ttgctgagat ttatcagctg
     1561 tatcttccac ttcatctttt gctttttcta acttttgaat atattgtttc aagcttgagt
     1621 tttcagcagt tgcttcgtct aatttctttt gtgtatctgt taactgagtt tctacatttg
     1681 ttttttcttg tgtcagtgtt gcgatttgtt gattcaaacc atttacagta ttttgtaatt
     1741 ctgaaagttt tgcttgtgct tcttgtagtc ttgctgtcca atctgcattc agatgattga
     1801 tttcatcatt tttttggttg atctcatcta gtttgacatt gatttcattt tgtttgcttt
     1861 gtagttgtgc atccttgctg actaattgac tttctaagtt ttgtttttct gctgccgatt
     1921 gatttttttg gttttctaat tcatttactt ttgtttggta ttcttggaca tctgcctttg
     1981 aatcttgcaa tgtctgttct ttttgtgcta gtcgagcggt aagatctgta atcgcttgct
     2041 ctttatctgt caatgtatga tcaagctgtg tcagattctc attgattgta tcaatatctg
     2101 tctctccacc ccacaaaata atttcatttg cgtaccgcgt gcctgtgtag ccaattagac
     2161 atagaaatgc aacgacaatc ccaccagtaa taaatttctt tttcatttgc atagctcctt
     2221 aatccaatac ttttacatgc taaaagtaag tgatctcaaa cacaatgtca agcgttttta
     2281 aattacatat gtaattttaa tataaatact atcaaatact catttaatcc tcctttttta
     2341 tctatttaaa aaatcttttt tatagagaaa aatgcaggtt aatactttct taaataaata
     2401 tttatggtga acaaaaacaa aaaagcaagt tttattaaac gtaacccttt tcatttcata
     2461 gattactgta tttattacaa aaaacg
//
LOCUS       DAXLPQ010000132         2474 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.138, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000132 DAXLPQ010000000
VERSION     DAXLPQ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.138"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(116..469)
                     /locus_tag="ACF3UO_002797"
                     /pseudo
     CDS             complement(116..469)
                     /locus_tag="ACF3UO_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(582..839)
                     /locus_tag="ACF3UO_002798"
     CDS             complement(582..839)
                     /locus_tag="ACF3UO_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658716.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(1436..1714)
                     /locus_tag="ACF3UO_002799"
     CDS             complement(1436..1714)
                     /locus_tag="ACF3UO_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658717.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(1748..1999)
                     /locus_tag="ACF3UO_002800"
     CDS             complement(1748..1999)
                     /locus_tag="ACF3UO_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658718.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT          777 a          492 c          329 g          876 t
ORIGIN      
        1 aatcatttgt ttaaaatttt cttcatatcg ggtcataaaa attcatcctc tcgtagataa
       61 gtttaattta ttcttgtctc tacgaaaagc tgtctaagat ttgatactaa caccaatcgt
      121 ccccaaaagg tagatcttct ctaccactag ctaatctact tctccatctt cgttctcttt
      181 tcatagaacc tgcgctgaac tcacacccgt taaactcagc tatgacagta tcttcaatta
      241 tgttaatctg tccatctagt tcgtattcaa tcctaaatgg aaattctcca taggtgattt
      301 ccggttcggg tattttaggt gagattaatg caaagaaagg aaatattaag cttggcaaca
      361 tcaaaaaaac tcctcctatg atcacaattc ccgatgtaat ccaaaatata atttgtacaa
      421 ttctcattga tccattgtat tccattttat tccccctatt actattcata tccgcctatc
      481 tatatcgatc ttccaatgca gagataattg cttccatacc ttgatttttt actgagttac
      541 ctatgcgaga tatcattctc cactaaggtg catcatattg tctatctaac atgattaatt
      601 ctccaatagg tgtatactcc tccaaaaaca acatttaatg catctccctc gacaacataa
      661 gctaccatgt ttgctgtata tgtgtttgag tctaattcat aagcagataa atttactgtc
      721 gctggattaa atataatcgc attcgtattt atagctactg aatttgctgc ttcagcacca
      781 ccttttgaat gtccgatcat tgtgatttca atagtaggat ttacgtggac agccctcacc
      841 gtttaccctg accattatag aaatcgctta cttttttgaa ctacgcaaca aaggatacaa
      901 tgctcctaac ttcactgtct ccatttttgt ccactaagga atataaaaaa taggcattaa
      961 ttcatttaat tcggtcacaa cacgttacct tttaaatcat tatactgtat ctcatacatt
     1021 attatcaata aactattata aaaatgcaaa aaatgcttta tcaatctatt ttgtaattgg
     1081 tcataatatc attgaaatca taccctgtat cgatttttcc tatgaatctc gtctatttgt
     1141 gattgacgaa aaagaggcaa gacagacact ggaatggtaa ttttacccac tattttgctc
     1201 caactatttg taatcgtacc cacttttgaa ataccgagat gatcatttta attgatatgc
     1261 tgattcccaa gcaaaacccc aagaaattaa atgctctatc gcatctagct tcttgggttt
     1321 tgcttatata aattccaaca tttaaatttt ttatgctgtt cggtctcaga aatgccgttt
     1381 ttgcttatat cacaatatca agatgtcaaa ttattcgtgt tgccgatgac tttgattaat
     1441 ttttttcaaa ttgtttatta agactaatgc tgtctttttg cagataccaa tgttcgaact
     1501 ttttaacatt atcatatgat cctgcaagtt ttaacttctt accattagat gttatcaaag
     1561 ttataattaa ccttgccttt ttcccattag gatcttttat tttatgaatt ttctgcaggt
     1621 aatctctcct aatggcagct atttttacct catcagtgct gataaaccat tgatcatcca
     1681 catacatact gcctgttatg ttgtgttttt ccatttcttc cgagaacgaa aagtttaagg
     1741 ctcgttctta cttccaaagt tgaatgagtc catggattgg acttagtgtg agaattgaga
     1801 acaacaataa gaatccatat cctcccgcaa acatccctaa ggctatactg tctctccatc
     1861 cataagtagg attagaagag aaaagagtca ccgtttgtaa taatatgaaa aggaataatc
     1921 cagcacaaac accaaagata acaactccaa acattgaatt tttatacaat gaccatttat
     1981 ttataggctt ttctttcatt ttacttcccc ctactgttct gttcacacgg aatgaattca
     2041 aagttcataa gccctcctct ttgaacatat gaatacgact tgctaactat actttaaaaa
     2101 agcttgtttt aagcggttat aggcgagttg taatctctat tcatctcatt agcaaataac
     2161 ttgccgaaaa gtctactgaa attaaagcag atagtggaag aattatttag ccaggataga
     2221 cactatttgt gaaacacatg tctttacttt tgaaattcta tgatgaaaag ccttggaata
     2281 cagtagctct taattggtaa tactttttcc attataaata acctcttttc attttatatt
     2341 tatcccctct aaaaataata tctaatctaa tattttaaac ttatatttcc ctcgctgtgc
     2401 taatagagca ttactaaata aatagaaact agaaaaaagc attacgcctg ccagaataaa
     2461 ccaattattt gtat
//
LOCUS       DAXLPQ010000133         2395 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.139, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000133 DAXLPQ010000000
VERSION     DAXLPQ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.139"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            316..570
                     /locus_tag="ACF3UO_002801"
     CDS             316..570
                     /locus_tag="ACF3UO_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3658719.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="ACF3UO_002802"
     CDS             571..888
                     /locus_tag="ACF3UO_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3658720.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="ACF3UO_002803"
     CDS             1447..2382
                     /locus_tag="ACF3UO_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658721.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          339 c          453 g          742 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DAXLPQ010000134         2335 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.140, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000134 DAXLPQ010000000
VERSION     DAXLPQ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.140"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(51..1598)
                     /locus_tag="ACF3UO_002804"
     CDS             complement(51..1598)
                     /locus_tag="ACF3UO_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFD3658722.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACF3UO_002805"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACF3UO_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFD3658723.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="ACF3UO_002806"
     CDS             complement(2043..2237)
                     /locus_tag="ACF3UO_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658724.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          653 a          483 c          420 g          779 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga agacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttacg ttaaaaatgt tttgc
//
LOCUS       DAXLPQ010000135         2320 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.141, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000135 DAXLPQ010000000
VERSION     DAXLPQ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.141"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            201..1097
                     /locus_tag="ACF3UO_002807"
     CDS             201..1097
                     /locus_tag="ACF3UO_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658725.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            1146..1520
                     /locus_tag="ACF3UO_002808"
                     /pseudo
     CDS             1146..1520
                     /locus_tag="ACF3UO_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1800..>2320
                     /locus_tag="ACF3UO_002809"
     CDS             1800..>2320
                     /locus_tag="ACF3UO_002809"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658726.1"
                     /translation="MTQTDFAELMGLSRSYIGDLENNRSNPSIKTLEAIARALDVPIV
                     ALINDSSTDNIVEPYESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMI
                     PNLKDVSKRIKYIRKKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVG
                     ETTTDWIKWGTLE"
BASE COUNT          906 a          324 c          434 g          656 t
ORIGIN      
        1 ggttgaattg atagatggac tcaaagaaga aaattcaaag ttaaaagaga agataaaata
       61 ctatgaatgt ttatttgatg gtatagagag tctgctgaac tcacgaaaaa atccctagtt
      121 tttatgaatg accgttttgt aaatctgatt gaaatagatt tatatgattt cggtatatga
      181 tatacattag gaggtgtcga atggaaataa atctttttga ggctggtaat cgaataaagc
      241 aaatacgaga aaaacatgga tatactatgg cagacttagg taaactggtt gatgccaata
      301 gtcctagcac aattaacaat tgggaaaagg gaaataactt acctaataga aagcgtcttg
      361 aaaaaattgc actattaggt ggtacttctg ttgaatggat aaagtatgga gatttttccg
      421 attatgttta tcgcttgaca caaaatatag aggaaaaaat tcttaaagag tacggagaga
      481 ctacactgaa caactaccgt gaagctcttc tagatgaact tacgattgaa aaaatcacat
      541 acgaagaaga tacaaagata ttagcagctg ccgaaaaaat caatacacaa aatatttttc
      601 aggaggtgaa gtacatgtat tctcctgatg aagattatcg aaatatagaa gtcaaaccag
      661 atttaggact gactgatgac aacaaaaata ttaaaatgat tggacaacgt ataaggaaaa
      721 taagaaaaaa agagaatatt acattagaag aattcggcaa actattctct cctacagctg
      781 ataaagctgt tataagcaac tgggaaaatg gtaaaaacct tcctaactca gaaagaatta
      841 aaaagattgc agaaattggc ggagtttctg aactttatct tatgacgggt gtcgattcaa
      901 gcgtagcaga atcaatgtat tttctatctg aagtagcatt ggatgctttg gaacgtctgt
      961 caattgagga agtcaataga ataattgaaa gcttcgccgg ttatcttaat gtgatttcaa
     1021 aaattgatga tccagataag cgagaaatat ctctcaatgc tatttgtcaa ctatcacttc
     1081 tcgataaaat gggttgattc acaaaaaata ttgaaagatt actttactca cgaggaggct
     1141 tagctatgaa acctaatcta tcgttaacta gtgaacgtat tagaaaaatt atcgaatcca
     1201 aaggtctgac attagaacga ttcggtgatt taattggcga cacaccaata agttctgtta
     1261 ataattggct tagaggcgtg tctttaccca ataaaaatag gcttttaaca attgcaaata
     1321 ttggaaacac tagtgtagac tggattaaat ggggaacttt ggaagaatac atagcttcat
     1381 accttataga ttcaggttat gagctatata ttaaagactt tccagagata ccttacaaag
     1441 tctttaaaga cattcaagaa aaatatagtg atacgttttc actagataaa gactatgagt
     1501 tattgaatcc tataataaaa tttactatag ggggcgttac tttgaataga ataaaatttt
     1561 atattgattc cagtaaaaag accattaaac aaattagtac agaaactggt attaactata
     1621 caactcttac gaactattac cgtggtgagc gaaatcctag aaatactgaa acatggaata
     1681 tccttgctga ttatttccat gttcctgtaa gttatttgat gggattagac gaaacaaatg
     1741 ttgaactcaa aaaccttaat attggaaaca acatcaaaaa tattagaaaa agtaaaaata
     1801 tgacacaaac tgattttgct gagttaatgg gtctatcacg atcatatata ggggatttag
     1861 aaaacaacag gagtaatccc agtataaaaa cactggaagc tattgcaaga gcattggacg
     1921 ttccgatagt agcattaatc aacgattctt ctactgataa tatagtagag ccgtatgaaa
     1981 gtttgacagc cgaaaatatc cttcttaaac aagaaaatga ggaattaaaa tatgaggtag
     2041 aaagcttacg aaaaagattg tatgaaatcc aacaagtagt aaatcaagga gctgaaaaaa
     2101 tgattcccaa tctaaaagac gtaagtaaaa gaatcaaata tatcagaaaa aaattaggta
     2161 tgactatgga gcaatttggt tctcatttaa gcaactcacc taaaagtaca attgctactt
     2221 gggaaagtgg tagaaatata ccttctcaga aaaagttaca gctgattgct atagtaggag
     2281 aaaccaccac tgactggatt aaatggggaa ctttagaaga
//
LOCUS       DAXLPQ010000136         2232 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.142, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000136 DAXLPQ010000000
VERSION     DAXLPQ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.142"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..378
                     /locus_tag="ACF3UO_002810"
     CDS             <1..378
                     /locus_tag="ACF3UO_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFD3658727.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /locus_tag="ACF3UO_002811"
     CDS             426..1826
                     /locus_tag="ACF3UO_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD3658728.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..2026
                     /locus_tag="ACF3UO_002812"
     CDS             1859..2026
                     /locus_tag="ACF3UO_002812"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658729.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            2080..>2232
                     /locus_tag="ACF3UO_002813"
     CDS             2080..>2232
                     /locus_tag="ACF3UO_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3658730.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
BASE COUNT          628 a          371 c          483 g          750 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt ttactggttc tgttgcaaag ttttaaatct actatcaaat
     2041 aaggtagaat aatagaaaaa gatagcagga ggaatgacga tgaatcattt taaaggaaag
     2101 caatttcagc aggatgtgat tattgtagcc gtgggctact atcttcgtta taaccttagc
     2161 tatcgtgaag ttcgagaaat cttatatgat cgtggcatta acgtttctca tacgacgatt
     2221 tatcgttggg tg
//
LOCUS       DAXLPQ010000137         2200 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.143, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000137 DAXLPQ010000000
VERSION     DAXLPQ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.143"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..503
                     /locus_tag="ACF3UO_002814"
     CDS             <1..503
                     /locus_tag="ACF3UO_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658731.1"
                     /translation="SNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGK
                     CLVNNQSVIDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKK
                     RESNFVKTYNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYG
                     IEVKSE"
     gene            complement(1063..1440)
                     /locus_tag="ACF3UO_002815"
     CDS             complement(1063..1440)
                     /locus_tag="ACF3UO_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFD3658732.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(1486..1674)
                     /locus_tag="ACF3UO_002816"
     CDS             complement(1486..1674)
                     /locus_tag="ACF3UO_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFD3658733.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            1866..>2200
                     /locus_tag="ACF3UO_002817"
     CDS             1866..>2200
                     /locus_tag="ACF3UO_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3658734.1"
                     /translation="MNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGDCMKPNPV
                     ETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERGFSLPNKERLIKIAELSNKTI
                     DWIKWGTLE"
BASE COUNT          801 a          316 c          408 g          675 t
ORIGIN      
        1 agagtaatct aatctttgag gggaaaaatt tatttttgaa tttaacaatt tcttttgaaa
       61 aagattatca taagctagat ttcaaagaag gagctgaatt aaccataaag tttactgatt
      121 tgtgtagcgg taaatgttta gttaacaatc aatctgtgat tgattttggt gacagcaaat
      181 atataagtaa cttcaaaaat aaaattaaag caatgaaatc aagggagcaa agccgaggag
      241 ttttttctaa aggcggtcat ggtcgaaaaa gaaaattaga tcaagataga tgggaagcca
      301 taaagaaaag agaaagcaat tttgttaaaa cctataataa tcaatgttcg gcaaaaatta
      361 ttcaaacagc tatccgcaat aagacgcaaa taatctgtat ttctgaacca gataaaaatt
      421 atggggaatg ggcttattat cagttgaaag aacaaataat aaataaaggg aaaagatatg
      481 gaatagaagt taaaagtgag tagaataaga aatcgttgat ttggcaacga aatagtgagg
      541 ggacactcac tcactgaagg gttagctctg tcaagttgtg taaccagacg gaaggacgaa
      601 tattgttgag gttttagaac catgtaaaac aacacagttc tcaaatgtta cggataaacc
      661 gtttgcggga aatcaggttt taaaaccatg taaaacaaca cagttctcaa ataaggcttt
      721 attgaattga tcagtagttt ctgttttaga gttatataaa acgacatggc tcttaaatag
      781 gagctaacga agaaaaagaa ggtactccgt tttggagtta agtagaaata aaaaaataga
      841 atcgttgatt tggcaacgag ttgaaaaata cgcaaaacta tggtcaccaa gggataaccc
      901 tgaaactgat gatcgctata tcttactagt agttaaacag tctaaatagt actcatttat
      961 tgtattgatt ctaagggaac ctgcaataaa tgagtactat tttactttta attccgctat
     1021 ctatgtcatt aggcaactaa attgttatta atatatttac gtttactcgt atatttttag
     1081 taacgcatct gtcaaaactt tagaaaaatt tattttatct ttttcccctc tagctactaa
     1141 ccattctggg actgtgacgt ttttgcgtac ggtctttttt tggataaatg gagaaggatc
     1201 actttgaata agagaaacaa ttttgttatt gcccaaatta tttagttgat gaatatctgt
     1261 tggagaagga actgaaatat cttcatcaat atagtaagct agaatcccat caagaaattc
     1321 tttagcattg gacatagctt cttcaaaatt atctccttgt gttgctccag caaaatcagg
     1381 aaaaactact gagtagccat tttcttcagc agaaaaaatt acagggtaac tttttttcat
     1441 ttccaccact cctttcgagt taatccaatg aactaaagga ctgggctatt tcagccctaa
     1501 gtcctttagt aacttctgct ctgtcccttt ttttaaatcc tgattactat gaacaggaat
     1561 aggaacgggt gggaatcctt ctttggctac aatatgatgg ctgccagtta tcctcaccac
     1621 tttccaacca tttttcttgg ctagtttgag cattttttta ccggtaagtg gcattcgcga
     1681 ctacctcctt acaaatatta ttatacgcat tatgcgtata aaggtcaaga gtttttacat
     1741 taaaagtaga atgtaagtgt cacaataggg tataccctat tgtatcatat ggtaaagtac
     1801 agtataataa ggtttggagg tgtaacacta gggtgtaaca caatgtgaaa tttggaggtc
     1861 attttttgaa caagaaacag gatcaagaat attatataga aaaattggag aaagagaact
     1921 tagaactcaa agagcgaata agatactatg aaaccaaatt ctgtaaaaga ggtgattgta
     1981 tgaaaccaaa tcctgttgaa acaggtaaaa gaattaaatc aattcgttct aattttggaa
     2041 tgactatgga acaatttgca gatttaattg gaaatgctca aaaaggaaat attaataatt
     2101 gggaacgagg attctccctt cccaacaaag aaagattaat taaaattgct gaattaagta
     2161 acaaaactat cgactggatt aaatggggaa ctttagaaga
//
LOCUS       DAXLPQ010000138         2104 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.144, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000138 DAXLPQ010000000
VERSION     DAXLPQ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.144"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            33..656
                     /locus_tag="ACF3UO_002818"
     CDS             33..656
                     /locus_tag="ACF3UO_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658735.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..>2104
                     /gene="trpX"
                     /locus_tag="ACF3UO_002819"
     CDS             1106..>2104
                     /gene="trpX"
                     /locus_tag="ACF3UO_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3658736.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAK"
BASE COUNT          749 a          346 c          446 g          563 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaa
//
LOCUS       DAXLPQ010000139         2067 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.145, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000139 DAXLPQ010000000
VERSION     DAXLPQ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.145"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..657
                     /locus_tag="ACF3UO_002820"
     CDS             <1..657
                     /locus_tag="ACF3UO_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658737.1"
                     /translation="QFLEELSGEEYRLFLNNNILKLISYAKKANSLSLVDNLDNLLPD
                     KLIYDENEDNSQKQIIIFELYLKWLSSLSVSPESNDDDKYFANKLFQFIFPDYSSMPF
                     FTLINFMLYVKEHLGYDDLVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYK
                     EQNIKTLELIKKNIKYYDPLLANKENIDKLLNAIADSDVRSPRIDELKEEILMYKELF
                     "
     gene            complement(654..1277)
                     /locus_tag="ACF3UO_002821"
     CDS             complement(654..1277)
                     /locus_tag="ACF3UO_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658738.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PHLDKFIKDLIIQILAMIAEQERTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQ
                     RRLVYENIVKDLNEGIAISKIAKNYNITRQTIYRIKNDIEYNSNQMN"
     gene            1553..1933
                     /locus_tag="ACF3UO_002822"
                     /pseudo
     CDS             1553..1933
                     /locus_tag="ACF3UO_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            1933..2067
                     /locus_tag="ACF3UO_002823"
                     /pseudo
     CDS             1933..2067
                     /locus_tag="ACF3UO_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
BASE COUNT          745 a          306 c          336 g          680 t
ORIGIN      
        1 caatttttag aagaattatc tggagaagaa tatagattat tcctaaataa taatatttta
       61 aaattaatat cttatgccaa gaaagctaat agcctatctt tagtagataa cttagataat
      121 cttttacccg ataaacttat ttatgatgag aatgaagata attcacaaaa acaaataatt
      181 atatttgaat tgtatttaaa gtggcttagc agcctgtcag tgtcaccaga aagcaatgat
      241 gatgataaat attttgcgaa caaactgttt caatttatat ttccagacta ttcttcaatg
      301 ccatttttta cattaataaa ttttatgctg tatgttaaag aacacttagg atatgatgat
      361 ttagtagaaa tgataaaggc atatgataaa gaaccttatc cattcaaagg aatcaatact
      421 ggttcagata tggctatgat ttcaggcgaa actgtagaag aaattctagc taattacaaa
      481 gaacaaaata taaaaactct ggaattaatt aaaaagaata taaaatacta tgatccttta
      541 ctagcgaata aagaaaatat tgataagtta ttaaatgcaa ttgctgattc tgatgttaga
      601 tctcctagaa ttgatgagtt aaaagaagaa attttaatgt ataaagaact tttttaattc
      661 atttgattac tgttatactc aatatcattc ttaattctgt aaatagtttg tctagtaata
      721 ttgtagtttt tagcaatttt tgaaatagct atgccctcat ttaaatcctt aacgatgttt
      781 tcataaacta aacgtcgttg aggatttttt gtatctgcac tatagagttt tggacgacct
      841 ttatagacgc catttgcttt tgcaatttta atgacttgcg cctggcgtcg tttagattcg
      901 gtacgctctt gctctgcaat catggccaaa atttggatga ttaaatcttt aatgaattta
      961 tccaaatgag gattgccaat tgcttcagcc atgatcggta gactggtgat gatcagctgc
     1021 acgtttttct tctttaggta attgactgaa gcaatgattt cgtcgtaatt tcttccaagt
     1081 cggtcgattg cttcgacaat aaaaatatct tggtctcgga caaactctaa agcttcctgg
     1141 aaaatcggtc gatgagtaat cgttgctcca gattgtttct cgatgaaaat tttttctgcg
     1201 ccgaactttt tcatttcttc aatttggcgt tgctcatttt gatcaatcga cgaaactcga
     1261 atataagcaa ttttcaaaat ttttacctac ttcctcaaac tatttaaaat acactcaaaa
     1321 tcaacactaa tttttttata cactataaag ctgtcatttt tctagataaa tggcataaat
     1381 tttcagcgct aagtgacaaa agcaactaat ttttcatgat agatttttaa atatctcaat
     1441 ctatctccaa aattagttgc ttttgtagct atagttgact atgaatatga caaataatta
     1501 gaaaaaactg tgccaattaa atatcaaaat gacaaattga tgaatcaaat tcaaattaag
     1561 gggggcaacc ctggaagtct taaatttacc ctcaatgaat ggtattgaag atgaaaattt
     1621 aaggcgtttg attaatagcc ttgtcattga attgtacaag tatcaagcag aatcagaacg
     1681 aaaaaaaatt aaggaacgtc aggcacaagg aatcgaaatt gctaagaaaa aaggcaaatt
     1741 caaaggtcgg caactgaaat ttaaaaaaaa tgatccacgt ttaaagcatg ctttcgattt
     1801 gtttttgaat ggtttatccg ataaagaagt tgaagaacaa actgggatca atcgccgaac
     1861 gtttagaagg tatcgagcaa gatataacgt gacagtagat caaagaaaaa acaatgaaaa
     1921 gagggatagt taatgagtac ggttatttta gctgaaaaac aagccaggca ttagcctacg
     1981 caagtgcttt aaaacaaagc accaaaaaag acggttattt tgagatcaaa gacccactat
     2041 ttacagatga aacgtttatc acctttg
//
LOCUS       DAXLPQ010000140         2020 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.146, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000140 DAXLPQ010000000
VERSION     DAXLPQ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.146"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            100..570
                     /locus_tag="ACF3UO_002824"
     CDS             100..570
                     /locus_tag="ACF3UO_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFD3658739.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            792..1895
                     /locus_tag="ACF3UO_002825"
     CDS             792..1895
                     /locus_tag="ACF3UO_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFD3658740.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          686 a          328 c          460 g          546 t
ORIGIN      
        1 gaatctctga agaataaatc acgtgatcgt gacgataaaa tacacttacg tcaggtgata
       61 aaaaatacat aagtagaaaa ctaagaggag gaacagaaaa tgaaagaagt tcaattgatc
      121 agaaaaagcg aactatcaga aggtggttgc aatgcatgcg gcgtagtaga agcaacaagc
      181 tatacattaa agcttggtgc caacaaagcg ataatctctg agttgacagt aggcggtctt
      241 gtggacagtc tggcgcttgc tgaaggtttt attggagaag atatttatga gatgttttca
      301 gaaatccgtc agttaaaaaa aggggaaaac tgcatagagg ttcatcatga gagcccgaat
      361 gtgagattca aacgtggtga taatgagatg atcttcaata atcatgtgtc cgatcacacc
      421 gagctatatg gaatcgtgaa tcaaatacta actgagcttt ttggattggg accttatgcg
      481 ttcaaggaag aaaacggtaa tccaaaatta aacgaagaat ggcaagaaac gattgaaata
      541 caaagaaaca acccgcactt atttcaatag gcatccacag tatttcgtaa aagggacttt
      601 gacacgactt ttgtcaaaat cccatcgttt tttatctatt tgtgttctaa acatttcttt
      661 cagagtagta acaactggaa tgactgaaat gtaaacagat tatttgcctg tatcaatacg
      721 gaagagtaat ataaagtgtg taaacgctat catattattc attcaatttt ttatagaggg
      781 aaggcattga aatggaaaaa acgtatcaag caggtacaaa tgaaggaata gtggatttta
      841 tcaatatgga agatttagaa atagccgctt cacaagtgat tccagctggt ggttatggtt
      901 acatcagcag tggtgctggc gacttattta cttatcaaga aaatgaacgg gcattcaatc
      961 atcagctgat tattcctcat gtattaagag atgtagaatt acccgataca actacacatt
     1021 ttgacaaaga aacgctgact gcaccaatca tcatggcacc agttgctgct catggcttag
     1081 ctcatgtgaa ggcggagaaa gcttctgcaa aaggtgtagc agattttggg acgatctata
     1141 cagcaagttc ttacgcttct tgtacattag aagagataag agaagcaggc ggggagaaag
     1201 caccgcaatg gtttcaattt tatatgagca aagatgatgg gatcaatttg gatattcttg
     1261 aagtggccaa gcgtaatgga gcaaaagcaa tcgtattgac agcggatgca acagttggcg
     1321 gaaaccgtga aacagaccgc agaaatgggt ttaccttccc actgccaatg ccgatcgttc
     1381 aggcttatca atcaggagta ggccaaacga tggatgctgt gtacaaatct tccaaacaga
     1441 agcttagtcc aaaagatgta gaatttattg ctgctcattc tgatttgcca gtctatgtga
     1501 aaggtgtcca gtcagaagaa gatgtctatc gttcattaga atctggtgct ggcggaatct
     1561 gggtatctaa tcatggtggc cgtcaactag atggtggtcc agcagcgttt gattcgttgc
     1621 aatatgtggc agaagcagta gataaacgtg taccaatcgt gtttgacagc ggtgtacgac
     1681 gcggacagca tgttttcaaa gcaatcgcat caggtgcaga tcttgttgct attggcagac
     1741 ccgttattta tggattgtct ttaggaggaa gtacaggagt ccatcaagtg tttgatttct
     1801 ttaaaacaga attggaaatg gtcatgcaat tagctggaac acaaacagta gaagatatca
     1861 aaaaaataaa attgcgtgag aatcgtttta tttaagaaac aaatgacgaa aaaaatagga
     1921 gtgcggcaga tgatgccgta ctcctatttt tatagttcaa ggatgtcact aatagaataa
     1981 tttgaaacga aaaaataaaa ttgaaatatt ttttcatact
//
LOCUS       DAXLPQ010000141         1980 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.147, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000141 DAXLPQ010000000
VERSION     DAXLPQ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.147"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..367
                     /locus_tag="ACF3UO_002826"
     CDS             <1..367
                     /locus_tag="ACF3UO_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFD3658741.1"
                     /translation="KKQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYL
                     PGDVKPVDRIMIKGLNQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESA
                     NDLKIELDTWLLGLDVTEK"
     gene            1331..>1980
                     /locus_tag="ACF3UO_002827"
     CDS             1331..>1980
                     /locus_tag="ACF3UO_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3658742.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQER"
BASE COUNT          657 a          305 c          461 g          557 t
ORIGIN      
        1 aaaaaaacag attgtaccaa aagaaatcga aacatggtgg cgtatagaaa tgcagctaag
       61 acgtggcaaa gcaacagatt ggcatgcgat ggttcgggaa agtttagata gctttgcaag
      121 tcctcattac ttgcctggag atgtaaaacc tgttgataga attatgataa aagggctgaa
      181 tcaagatcat tcagagtggg cgtatattag cagaaatttg aaatatagat tgcgcaaatt
      241 gttgaaagaa gaaagccaaa acgatgagtt gacgaatcat ttacgagaga cgtttaagga
      301 atctgcaaac gacttgaaaa tagaattaga cacgtggctt ttgggtttgg acgtgacaga
      361 gaagtgatac cgaataagaa aagtcagatg agtgagagta aatttacgtc aatgtttaat
      421 gacgtgagtt tacgataagc gattattttg cgtgaagcaa aataaagcgt aaaaggagtt
      481 gagagcgtga cacgctttcg gctccttttt tcgttgtcac ttgtgacagc gaataccctc
      541 ggagagcatt tggaattgtg acagccatgt cacaattagg aaaatgttta ctctttgtca
      601 aagagtaaca gaaaggttta cactcttttt attagcgaca gcgcgaagga ggggtttaac
      661 ttggggttta gtatttcgtt caaaaaggga acaaagaata caagcatttc tcataataat
      721 cgtgagttaa ctgatagcca aaaaatcaat ggtttgtctg gtagaaaata attagcagat
      781 ttacaagtgg gaaataaaaa gctgaaagaa gaaaattgca tttcaaacta cattttctac
      841 aatagctcta aaatggcata ttttgcgttc tgagcggttt tagcgtttat ttcgtttagt
      901 tatcggcaca atcgttaaaa cacgttagag gagcgaaaat ggagcctgta aggcgactgg
      961 tagcggaacg atcgtgttag attgtgaaaa ccgatagctg aatgaaataa acagcgggtg
     1021 cgccctttcc atttcggcag gaggaggctc aaggggttcg gggaatgaaa ttccctgagg
     1081 tctttttatt tttttaggag gagtgctata atcaaagaaa acgagaaaaa agagcaaaat
     1141 aaaagccgag cagtgcgcta acactctcga ctatttacgg aaactacttc acctagctcc
     1201 gtaactcagg ttcattatac gaatattttt aggtttcttc aagctagaga tttttggata
     1261 tgaattttta gggttacgtg aactctggaa attctttcca aaagtctctt ttttcgtctg
     1321 gaggacgaaa atggcaaatg aaaatcagtt gagtgaaatt caatcaaaaa ttgaaggtcg
     1381 aggggcagaa aaaagaacaa cgataaatca gctcgaaaaa cttaaccgta tttctaacag
     1441 gcggttaagt gttgacgata aggtacaccc cctaaaatta agttggtcaa tcgatcgaat
     1501 tacaatcgtc ggaaaactga atgataccat agcttattgg acgcaaaatg gagttgtgtt
     1561 tgtcgatttt gagcaattaa tgcgtttgaa tgaaaatcaa gggtatttga agtcggttgg
     1621 tacaaatggt tggcaattat ttgaccaata tggagaagat atcgcctata tcgaaatgtt
     1681 aaaatttcac cctgacaaag gtcgtattga ttttaatcca aataaaattg gcgagttttt
     1741 aaaggggtcg atgaaacaat tcattcatga tttgtttctg gatgcgcatt tctcacgtgc
     1801 agatattgct tgcgatattc tcggtgttcc tgatgatttt attacccagt atcgaatcgt
     1861 tgaccctgtg tcttttaagc caatttatgg ccgttctggc aaattagaaa cagcgtactg
     1921 gggtagtcgt gccagcgagc gacaagtgcg gatgtacaac aaaaagcttg aacaggaacg
//
LOCUS       DAXLPQ010000142         1970 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.148, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000142 DAXLPQ010000000
VERSION     DAXLPQ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.148"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            191..424
                     /locus_tag="ACF3UO_002828"
     CDS             191..424
                     /locus_tag="ACF3UO_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HFD3658743.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            421..828
                     /locus_tag="ACF3UO_002829"
     CDS             421..828
                     /locus_tag="ACF3UO_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFD3658744.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(1279..1788)
                     /locus_tag="ACF3UO_002830"
     CDS             complement(1279..1788)
                     /locus_tag="ACF3UO_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658745.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
BASE COUNT          679 a          301 c          326 g          664 t
ORIGIN      
        1 atttaaaata aatggtatac ataaataggg aaggaaatag aagggagcaa tctaaatttt
       61 ttgaattttc ttaattaatt atatagaaag aacaatcttt ctatagagtt agacatgaga
      121 gggactatgc ttgatttaaa atcaacaagc gtatatactg tatatacaaa gaaaaaggag
      181 ggagaagact atggcaatta aagaaagaaa atttagggaa gtggggaact cagtagtatt
      241 aactatttca aaggagtttc ttaaagaaaa tgggttaaat cccggagata cggttttttt
      301 agatgaagaa aaacttcgag cggcaattac aaaaaaacaa gccttatctg atgaaattga
      361 tttagcaata tctcaagcat taactgaata tgatactact tttagagagc ttgtcgataa
      421 atgagtattc attacctaga agccaaagat attataaaaa tgaatgtaat ccaaataaaa
      481 aaatactctc ctaatgaacc ccttggtgta aaggatgcga atgctttaga aatgtgtgta
      541 gggcaacttc gagcctcagc ttttggtgaa gaggtttatc cttcgattta tgaaaaagca
      601 gctatcctac ttatacaatt gataaagaaa catccttttc acaatgcaaa taaacgtact
      661 gctttcttag ctacttttgt ctttttgaaa atcaatggac agcttttagc tattgatcaa
      721 aaagatgctg taaatttagc ggtatatatt gctacgtatg ataaggattt cgatcaacta
      781 aaatatgaag tgatcaacac tataaagaca catacgcagc ccatttaagg agttactgta
      841 tgtgtcttta tagggttatt agctgctata gcgaaataat tgaagtaaat tacaaatagc
      901 tataattcaa atccaactat atagaaaacg taaattttct atatacttgg atatgctgga
      961 atgtttaaga gaataattac atttctagaa aatacaataa aaattacagg ataattagcc
     1021 atatcctacc tcctctagca gttgctcaaa agttagcact aagtaacttc ttttttgttg
     1081 ctggtaacaa tttatcaata ctaaaatagc gtttaagtat ctaataaata ctaattttaa
     1141 agctcttaat tattatgaaa cacgatataa caatattgct atatcgtgct attgtaatat
     1201 tatacatttg aagacagcgt attcttgttc taatatcagg aattttttat aaatatcagt
     1261 catattaaga ctcaaaattt attggtatgt tcctctgtat agagtttgac cgtctaccat
     1321 tatatagcaa ttattatcat tgttgtcttg caccaatata ccgttaaggg tagcactagg
     1381 agtagtaaca atcactggaa actcatgaga aagctcggtc atttttcctg ttctgctaga
     1441 atcgtgttct attgtcaagc catttactat aaacgtgaat actttacttc ctattgttat
     1501 agtagctttt tgagaaacag tttctgtagc tggagctgtg cttctttccg aatttgttag
     1561 ggtttcactg gattcattgc tataaacaat tgtagaggat tctacggctt cttgagtgtc
     1621 cacgttggtg ctgctagctt catctagctt ccttttgtat tgttcgttac tgattgctaa
     1681 gctttcccgt tggtcatcaa gcttattcat ttctgtaatg gtataaaata atcctcctgc
     1741 tagtgctata ttaacaacta aactaaccgc aaataatacc tttttcattc ttccttctct
     1801 tctttctctt tttgtaattc cttacttttg gataggctac aattaactag acagaaaaat
     1861 taaggtgtgt agactagaag aaaacatacc aggaggaatt tttatgtcta agagaacacg
     1921 aagaactttt tcacaagaat tcaagcaaca aatcgtcaat ctttacttag
//
LOCUS       DAXLPQ010000143         1913 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.150, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000143 DAXLPQ010000000
VERSION     DAXLPQ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.150"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            4..396
                     /locus_tag="ACF3UO_002831"
     CDS             4..396
                     /locus_tag="ACF3UO_002831"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658746.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDDIVYVYDYEKGDK"
     gene            397..1836
                     /locus_tag="ACF3UO_002832"
                     /note="aph(2'')-Ia"
     CDS             397..1836
                     /locus_tag="ACF3UO_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFD3658747.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          803 a          138 c          326 g          646 t
ORIGIN      
        1 tttatggaag aagttttaat tgatgataat atggtttttg atattgataa tttaaaagga
       61 tttcttaatg ataccagttc atttgggttt atagctaaag aaaataataa aattatagga
      121 tttgcatatt gctatacact tttaagacct gatggaaaaa caatgtttta tttacactca
      181 ataggaatgt tacctaacta tcaagacaaa ggttatggtt caaaattatt atcttttatt
      241 aaggaatatt ctaaagagat tggttgttct gaaatgtttt taataactga taaaggtaat
      301 cctagagctt gccatgtata tgaaaaatta ggtggtaaaa atgattataa agatgatata
      361 gtatatgtat atgattatga aaaaggtgat aaataaatga atatagttga aaatgaaata
      421 tgtataagaa ctttaataga tgatgatttt cctttgatgt taaaatggtt aactgatgaa
      481 agagtattag aattttatga tggtagagat aaaaaatata cattagaatc attaaaaaaa
      541 cattatacag agccttggga agatgaagtt tttagagtaa ttattgaata taacaatgtt
      601 cctattggat atggacaaat atataaaatg tatgatgagt tatatactga ttatcattat
      661 ccaaaaactg atgagatagt ctatggtatg gatcaattta taggagagcc aaattattgg
      721 agtaaaggaa ttggtacaag atatattaaa ttgatttttg aatttttgaa aaaagaaaga
      781 aatgctaatg cagttatttt agaccctcat aaaaataatc caagagcaat aagggcatac
      841 caaaaatctg gttttagaat tattgaagat ttgccagaac atgaattaca cgagggcaaa
      901 aaagaagatt gttatttaat ggaatataga tatgatgata atgccacaaa tgttaaggca
      961 atgaaatatt taattgagca ttactttgat aatttcaaag tagatagtat tgaaataatc
     1021 ggtagtggtt atgatagtgt ggcatattta gttaataatg aatacatttt taaaacaaaa
     1081 tttagtactg ataagaaaaa aggttatgca aaagaaaaag caatatataa ttttttaaat
     1141 acaaatttag aaactaatgt aaaaattcct aatattgaat attcgtatat tagtgatgaa
     1201 ttatctatac taggttataa agaaattaaa ggaacttttt taacaccaga aatttattct
     1261 actatgtcag aagaagaaca aaatttgtta aaacgagata ttgccagttt tttaagacaa
     1321 atgcacggtt tagattatac agatattagt gaatgtacta ttgataataa acaaaatgta
     1381 ttagaagagt atatattgtt gcgtgaaact atttataatg atttaactga tatagaaaaa
     1441 gattatatag aaagttttat ggaaagacta aatgcaacaa cagtttttga gggtaaaaag
     1501 tgtttatgcc ataatgattt tagttgtagt catctattgt tagatggcaa taatagatta
     1561 actggaataa ttgattttgg agattctgga attatagatg aatattgtga ttttatatac
     1621 ttacttgaag atagtgaaga agaaatagga acaaattttg gagaagatat attaagaatg
     1681 tatggaaata tagatattga gaaagcaaaa gaatatcaag atatagttga agaatattat
     1741 cctattgaaa ctattgttta tggaattaaa aatattaaac aggaatttat cgaaaatggt
     1801 agaaaagaaa tttataaaag gacttataaa gattgattat ataatatatg aaaagctatt
     1861 ataaaagaca ttagtattaa atagtttaaa aaaatgaaaa ataataaagg aag
//
LOCUS       DAXLPQ010000144         1876 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.151, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000144 DAXLPQ010000000
VERSION     DAXLPQ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.151"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            239..919
                     /locus_tag="ACF3UO_002833"
                     /pseudo
     CDS             239..919
                     /locus_tag="ACF3UO_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
BASE COUNT          677 a          257 c          315 g          627 t
ORIGIN      
        1 tttaaacggt agttacttag ttcttctttg atttgcgtga aatagagggg atttattttt
       61 ctggttacgt gattaaaaaa tccaaaaaat gagcatagga acggttatga ttttagggtg
      121 tgttttaatg agatattgtg atttcattaa caagtgtatg ataatcggtt cttttgcaaa
      181 gttttccaaa aaatctattt tagtgtaaaa ttgagaaaaa aacagagagg acagagtaat
      241 gaatcatttt aaaggcaaac aattcaaaaa agacgtcatt attgtcgctg ttggttacta
      301 cctgcgttac aatctaagct atcgtgaagt tcaggaattg ttatatgatc gtggaataaa
      361 tgtttgtcat actacgattt atcgttgggt gcaagagtac agcaaagtcc tctattatct
      421 ttggaagaag aaaaatagac aatccttcta ttcatggaaa atggacgaaa cctatatcaa
      481 aattaaggga cgttggcatt atctttatcg tgcaattgat gcggacggct taaccttaga
      541 tatctggtta cgaaagaaac gggatacgca agcagcctat gctttcttaa aacgactcca
      601 taaacagttt ggtgagccga aagcaattgt gaccgataaa gcaccttctc ttggctccgc
      661 ctttagaaag ttacagagtg tgggtttata tactaagaca gagcaccgaa ctgtgaagta
      721 tatgaacaat ttaatagaac aagaccatcg acctattaaa cgacgaaata aattttatca
      781 aagtctccgt acagcctctt ccacgattaa gggcatggag accattcgag gaatatataa
      841 aaagaactga agaaatggaa cgctcttcgg cttttcggtg tctactgaaa tcaaggtatt
      901 aatgggaata acagcctaag atatttggag ttcagagagg gcgcgtttga ttttcaaact
      961 tcgcaacaga acccattagc aatatataaa agaaggtatc aagagtcaca gtgaatttat
     1021 tccgaaaagt gaaaagagca aatataaaat ttaataaaaa taagaactaa ataggaaaac
     1081 gtagacgtaa ttttctacgt tttccttttc atatatatta aatattacgg aaaattatat
     1141 aaactaattt agtgttttgt ttgtaattcc taattttgct ccacttttag ataattttta
     1201 ggtctattta actcattaga cattctatgc tcatttttct ccaaatttgt ttcaactctt
     1261 tcgtacttaa ttttgcgtat ttgaaaattc ttcttttaga gtacttttat tacgatacta
     1321 gtatgatata tatctacagc aaacagttaa aatcttccta aaataagcga atagcattcc
     1381 taaaacctat aaaattttta gatgaagcga caagtggaca attaataaac tacttgaaca
     1441 tgaaattatg gatcaccttt caaatttaga aaatggaatt cttatactta ttgcgcaaca
     1501 tttattgatt gcaaaattat gtgacaaaaa gaactagtag aagaaggaat aatggcttga
     1561 taataaagta ctacctatta aaggtagtac tttatttaat ttagtataaa ttaacatact
     1621 actatatttt aggtttcata ttatataaat taataatata ctaccatttg ttggtagtat
     1681 aatttaaagg taataagtta ttcttttatt actatgtttg ggttttatag caaagaaagt
     1741 ttaataagag tttggaccta gcaaacaata ttaatgaggt cattaaatct tattatcttt
     1801 agtgatataa tgaaatatct acacgacaaa attatgatct tgcgtaaagt tataaaatat
     1861 taataaaaat atttta
//
LOCUS       DAXLPQ010000145         1867 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.152, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000145 DAXLPQ010000000
VERSION     DAXLPQ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.152"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..471
                     /locus_tag="ACF3UO_002834"
     CDS             <1..471
                     /locus_tag="ACF3UO_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3658748.1"
                     /translation="IEKHLAEKDPDNKKIYKENLDKYIEKLNTLDKEAKSKFASIPND
                     KKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKHLVERLRTTKVPSLFVES
                     SVDDRPMKTVSKDTNIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            489..720
                     /locus_tag="ACF3UO_002835"
                     /pseudo
     CDS             489..720
                     /locus_tag="ACF3UO_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
     gene            1598..1867
                     /gene="rpsN"
                     /locus_tag="ACF3UO_002836"
     CDS             1598..1867
                     /gene="rpsN"
                     /locus_tag="ACF3UO_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3658749.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAVGDHTDLAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
BASE COUNT          726 a          234 c          317 g          590 t
ORIGIN      
        1 attgaaaaac atttagcgga aaaagatcct gataataaaa aaatctataa agaaaatcta
       61 gataagtata ttgaaaaatt gaatacacta gacaaagaag caaaatctaa atttgcttca
      121 attccgaatg ataaaaaaat gattgttaca agtgaaggat gctttaagta tttctcgaaa
      181 gcgtataatg tgccttctgc ttacatttgg gaaatcaaca ctgaagaaga aggaacgcca
      241 gatcaaatta aacacttagt tgaaagacta cgcacaacaa aagttccttc cttatttgta
      301 gaaagcagtg tggacgatag accgatgaaa acagtatcga aagataccaa tattcctatc
      361 tattcaacga tttttactga ttcaattgca gagaaaggac aagatggtga tagttactac
      421 gcgatgatga aatggaacct ggataaaatt gctgaaggtc tttcaaaata aattggagga
      481 aaaagagtat ggtaaaaatt aaaccaacta ctatactgat ttatttatta gcaattcagg
      541 aattgacgaa aagaaaaaaa gttaaaaaat aaagatttag caaaaattct aagcattact
      601 ccagcatctg taagtgagat gttggctaaa cttagatatg aaggttattt aaacataggg
      661 tgtcaattga caaatagagg gaaagacttt attgacaatt acaaaaagag ctttatataa
      721 aagacttttt atttagaaag gataagaaaa tgactattgg agtaattatg ataggactta
      781 tcctaatagc tggatataat ttttttaaat ctttcttgga ttattttaga aaaggcgaat
      841 gatttagatg agtatattac ttcttatagg attacttttt taatcagcta ttctgttgct
      901 gctcattagt ttaggtttaa gcaatgagtt taataataga cattaatgtt taaaaattta
      961 tagaattaaa aatatcatat aaggcgaatt ttctcatata gactaggtac tacgtgccac
     1021 ttactgaaag ataatagaaa atgaactaag ttattttcaa aaggatgtac ttcatcaaat
     1081 taagatagct ttgtttgtct gaacaatcta tctaaaaaag ataagttcta tcgagatgat
     1141 aggataggct tataattagc ctataaattt ttggaataca gctacaattc tttttcaaat
     1201 tagttactta atgtttattt cttataatat aagaattggt cacaatctta caaaatcatt
     1261 aataaacgag ttaaacataa aagattgaat aaaactatag tttctttcat aatgccgttt
     1321 taagtagaga aaagctactt aaaacggtat ttatgtttta atggactaat aaaaatgaac
     1381 cattattttt tgcacttaaa ctacaagttc ttttaattaa tctgattatc tctatgtatc
     1441 gataaaatca ttttcaaatg gatatctatt catatgattt ttatttcatg ttatttattg
     1501 ttgacaagag aaatttttgt tggtaaagtg tcaatgtcaa aacgtaacgt ttacgatttg
     1561 tgacgtctaa atcaaaacag aaggagtata aatgtatatg gcaaaaaagt ctaaaattgc
     1621 taaagcaaag aaacaaatgg caatgattga aaaatatgca gacaaacgtc aagaattaaa
     1681 agccgtagga gatcacaccg accttgctaa attgccaaga gattcaaatc caaatcgtct
     1741 gaggcttcgt gatcagacgg atggccgtcc aagagggtat atgcggaagt ttggtatgtc
     1801 ccgtattaag tttagagagc ttgcccatca aggtttgatt cctggagtaa aaaaagcaag
     1861 ttggtaa
//
LOCUS       DAXLPQ010000146         1764 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.154, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000146 DAXLPQ010000000
VERSION     DAXLPQ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.154"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(430..1002)
                     /locus_tag="ACF3UO_002837"
     CDS             complement(430..1002)
                     /locus_tag="ACF3UO_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658750.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGIKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1018..1623)
                     /gene="fic"
                     /locus_tag="ACF3UO_002838"
     CDS             complement(1018..1623)
                     /gene="fic"
                     /locus_tag="ACF3UO_002838"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFD3658751.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          517 a          361 c          259 g          627 t
ORIGIN      
        1 taatatcaca ataggaatgc tgtttattat attagcagca gtgctgattt ttatgatagt
       61 tatttggttc ttaaatgaaa gatctaaaga caatcaacac cgtagggata tggagataaa
      121 atcaatagag tcaatagatt atttatcgat aataacacta aaaaagccac gttcctaaac
      181 gtgacttacg ctgaacgata tgtgttgttt ggtagacgaa caaatcgttc attataaata
      241 tatgatggta tcctaatata gtaagcgtgg ctagcatacc tttaattact ttacctttta
      301 cagttaccat acacattttt tgagcagaaa tcaagtaaat aaaaaaatat tatatttcac
      361 aacatgctaa tagactcata tctagaacgc attaagtatt tacctgtctg gttcgctgag
      421 acttcttttt taactttctt caattttctt ctttattcta aaaagcgtac tgcgactgaa
      481 accggttata gcttcaactt ccttatacga tttacctgaa gtaagcagtt catatgcgtg
      541 cctcttcttc ggtgtgattg ttgctttcgg acgtccttct ctgaaattag gattattctt
      601 tcttgcaaac atttttcctt cttgggtacg ttccacaatc atatcacgtt ccatttctgc
      661 tacactcaac aacgtccgtg tcaccattcg ccccatggac gtattttcaa tcgttcctag
      721 attcaaaacc ttgatcgtta cgttatcatc gagtaaaggt tcaatgatct ctaatgcttc
      781 tctcgtgtta cgagcaaatc gatcaagctt cgtaacaact atttcatctc caggcttcag
      841 accagccaac agctgattga attttggccg atcccgtttt atacccgtaa atttttctga
      901 aaaaatattc ttcttctcta cgccgttctc aagcaactgt tgaatttgtt cttttgtact
      961 ttgagaagcg gttgagacac gtgcatatcc atatttcgtc atttggtcca cctactttta
     1021 caaatcatct atcgtatact cagaataccc ttcatagaaa tagctgacat cgattccttt
     1081 catatataac tcgcgatcgt caattttatc agtcagagca ttggaaatta gatagcgtat
     1141 ttccaaatcg tttatgggac ttcgctccat tgcagaaaga tagtctgctt tatcgattaa
     1201 gttccaatct acaacttttt gcaattcttc ctttaaaatg agatccagcc aaattctagt
     1261 acttcggcca tttccttctc gaaatgggtg agcgatattc atctccacat atttcttgat
     1321 aatctcttca aaagaagttt gtggcatctg atcaatatgc tgtaacgaat gttctaaata
     1381 cataactggt gcaaatcgaa aatttccttt tgcaatattg accgatcgga tttttccggc
     1441 aaaatcgtaa atatccgaaa atagaaattc atgaatttca gataaacctt taaatgtacc
     1501 aacttcgatt tcatttattt ttccacaatc gtacaattct ttcgcttttt gtttactgag
     1561 tttttcttca accttagcca actcaacttg attggttaat cccaatttat tctctaaaat
     1621 catgcgaaat ctccttaact ttatgacata agtttatgaa acactctcaa ccccattata
     1681 tcgcgatttt gtttatgtgt caaaaactat taagtttctg acccccgata gatttttcaa
     1741 gtgtctctat tttgcacagt ctag
//
LOCUS       DAXLPQ010000147         1618 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.155, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000147 DAXLPQ010000000
VERSION     DAXLPQ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.155"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(183..1502)
                     /locus_tag="ACF3UO_002839"
     CDS             complement(183..1502)
                     /locus_tag="ACF3UO_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFD3658752.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          481 a          299 c          322 g          516 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggca
//
LOCUS       DAXLPQ010000148         1595 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.156, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000148 DAXLPQ010000000
VERSION     DAXLPQ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.156"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            383..>1595
                     /locus_tag="ACF3UO_002840"
     CDS             383..>1595
                     /locus_tag="ACF3UO_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFD3658753.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNDSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKH"
BASE COUNT          520 a          305 c          286 g          484 t
ORIGIN      
        1 ttgtctaata gtttttattc aaaatgtttc tagattataa aatttattga ataacacatt
       61 cctaacggaa tttgtttcga tattgtgtga tttctcagag tacaatggat gtatggaaag
      121 gatccaacgg gaatttgcta tttcctcctg tagcgtttgt ctaccctgtt tagtctgtta
      181 cccgaaccac tgttatcact accaactcat tagctgtttc gataatggac tagactttca
      241 aatagtagtt tggaaggcag cttctagctc ttttatcacc gtattctatt aggcgaggtt
      301 gtggctatac agtgagtttc tgggaaatcc cacagtatcg aagcattttc caaaatttat
      361 atcgaaagga ggtccttctt ccatgaaatt atttgtcggt attgacgtta gctctgaaaa
      421 actagatgtt tgttttttaa cagacgacaa tcaattgtct atcttatctg aaatctctgt
      481 tgccaatgac atcgaaggtg cttcattcat acgagaaaca attcttgaat tcaatgacag
      541 ctaccacttt gatcaaattg tgattggcat ggagtcaacg tccatgtaca gcttccatcc
      601 ttccatgttt tttcatgaag atgagaaact aaagaagctc aacacacttg taacgattga
      661 aaatcctttt cgggtgaaac aatttagtcg catgtttgat gagaataaaa ctgatcgaaa
      721 cgatgcatta agaatcgctg atttcttgcg tattcaacga ttcacaactt cccctatcaa
      781 agaagagaaa tacatggcct tacagcgttt aacacgtact cgctatcaac ttattaagca
      841 attgattcgt acaaagcaac attttcttga aaatctaacg tacaaatgta atacgcttgc
      901 tcgagaaatg cgagacgaat cgacgagtct ttttagtgca accctcattt cactcatgac
      961 ggaagatttc acattggatg aacttgctga gcttccttta gaagctttct gtgatttact
     1021 tcaagaaaaa ggaaaaggcc gtttcaagca accagaaaaa atcgctaaag caattcaacg
     1081 tgcaattacc atgagttacc gcctaggtgc tcttgcacaa gaatcaatta atgttgtttt
     1141 aagtgttctc gtacgagaaa tacgagcact tgaaaaaaat atcaaagaat tagataaagc
     1201 catcgaacaa gtaattgttg tcattccaga atatcaatgc ttaaccagta ttccaggcgt
     1261 tggtaaagtc tatgctgccg gtttaatcgc tgaaattggt caaatcgaaa gatttgaaga
     1321 tcagacaaaa ttggcaaaat acgctggatt aagttggaaa gtgaaccaat ctggaaacta
     1381 tcagtcgcaa aatacacctc tgacaaaaca aggaaatcga tattttagat actacttagt
     1441 tgaagctgcc aactctgtaa aaaattatct tcctgaatac aaagcttttt atcaaagtaa
     1501 atataaggag gttccaaagc atcaacacaa acgtgcactc gtcctaaccg caagaaaatt
     1561 tacgcgtctg gtggatacgc tactacgtaa acacc
//
LOCUS       DAXLPQ010000149         1580 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.157, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000149 DAXLPQ010000000
VERSION     DAXLPQ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.157"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            192..887
                     /locus_tag="ACF3UO_002841"
     CDS             192..887
                     /locus_tag="ACF3UO_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3658754.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFA
                     QLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKS
                     AYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKAKGVTELAI
                     YQKRKRIMVPLPV"
     gene            complement(924..1421)
                     /locus_tag="ACF3UO_002842"
     CDS             complement(924..1421)
                     /locus_tag="ACF3UO_002842"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658755.1"
                     /translation="MNNQIALAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(1477..>1580)
                     /locus_tag="ACF3UO_002843"
     CDS             complement(1477..>1580)
                     /locus_tag="ACF3UO_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3658756.1"
                     /translation="LESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          507 a          284 c          254 g          535 t
ORIGIN      
        1 aataattaca cacacacaat tttttaaggt cttaaaacca tcatatatgc aaaagaagct
       61 aacctttatt actaaattag acccgtggtg ctagttaatt ttttcctaga ggaaaatgtc
      121 taaacatgtt ggtaaatcaa caaaaaaacg catatagtag tctcaaaact cccaagaaat
      181 gaggactaca tatgcgttca tcaaaatata ctgaacattt tgacttagcc aatcctgtta
      241 ctaaagtcga tgatatcccc gattatgaaa tgtacagtca aacaatcgat agcttaaata
      301 agcgttttgg caatcgtgtt ttaaaaggca tagaaatcgg ttacatcgct tctgaaaagg
      361 atcggatcat cgactattta gccgataaag attacgattt aaaattactc agtgtgcatc
      421 ataatggtca atttgattat ttagatgacg aagtcaaaga tatggatcct gctattgtga
      481 ttcctcagta ttttgcacaa ctttcagaag cactagttgt tatagaagca gatgtctttg
      541 ctcattttga ctatggtttt cgggtatttg gtctatccgt tgctgaattt aaacaatatg
      601 aagcgcagtt tttaccgatt ctagatcaag taatcaaaaa taaattggca ttcgaattaa
      661 atgctaagag cgcttacttg tatgacaatt tagcgttata tgaatatgtc atcgatttat
      721 atctttcacg tggtggtacc ttgtttagtg ttggatcaga tgggcattac cttgaacatt
      781 tccgtttcca tttcgatgat ctttttgctc tgttaaaagc aaaaggtgtg acggaattag
      841 cgatttatca aaaaagaaag cgaattatgg ttccattacc agtctaaaaa aacgtcctca
      901 gcatcaaaag tgaggacgtt tttttagatt tctttttcta aaatcggaca aatacgatct
      961 tgttttccta aaggaaaatg tttgatcccg atttttttaa atccatgacg ttcataaaaa
     1021 cgaatacctg catgattttt ttcataaaca gtcaaacgta aataacgttt ttgtttcgtt
     1081 ttagcataac gattcgcttc atcgagtaac cgttgcccta accctttgtt ttgataatct
     1141 ttgagcagat agagccgttg aatctctata gcatcttttt catcattgac tttcatataa
     1201 ccaatgagta tttgatgatc cttaatacca ataaatttac tggttgactg tgccaattct
     1261 actgccaata tttcagttgt caattgtgtc tgtaaatatc cttgcatatc aagtggatct
     1321 gcgccatcga taaacgattc ataaaaactg acaacactta caacttgtaa agcatctaga
     1381 tcatcataat ctaaatacgc tagtgcgatt tgattgttca tctaactcct ccttttgaca
     1441 tagtatacta taaatcaccc gtggtgctag ttaattttaa tatcctaaag aatatctcaa
     1501 agttccttca aaacgtcgtt gtgctcgact taatagaaca ctgtaagcca gtaatatgct
     1561 ttcaaatcta ctctctagcc
//
LOCUS       DAXLPQ010000150         1557 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.158, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000150 DAXLPQ010000000
VERSION     DAXLPQ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.158"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            64..846
                     /locus_tag="ACF3UO_002844"
     CDS             64..846
                     /locus_tag="ACF3UO_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658757.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            886..1497
                     /locus_tag="ACF3UO_002845"
     CDS             886..1497
                     /locus_tag="ACF3UO_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3658758.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
BASE COUNT          624 a          204 c          292 g          437 t
ORIGIN      
        1 tatttacaaa atattactca aaagaatttg aagtaaccca aattccataa gagaggtgat
       61 tgtatgaagc caaatccttc agaagcagga aaacgaatca aacaattacg cctttcatgt
      121 ggttttacta tggaagaact tggaaggaaa atagataatt caccacgtgc gaccatatcc
      181 aactgggaac gtgggaccaa tttaccaaat ccacaaaagc tgaaattatt atcaactatc
      241 actaattcaa caattgactg gattaaatgg ggaactttag aagaatatat aacttcatac
      301 cttatcgata tagggtatga gctatatatt aaggactttc cagaaatacc tcacaaagtc
      361 tttaaagaca ttcaagaaag atatagtaat acgttttcgc taaataaaga ctatgagtta
      421 ttgaatccta taataaaaaa tatatttaca aaatattact caaaagattt tgaagattat
      481 cgagacatag aagttaaacc agaccctaaa aaggtaggga gaaaaattcg ttctattaga
      541 aaaaaattag gacttactat gcaggaattt gggtacgagg tttctaattc tcctagaagc
      601 actgtgtcaa catgggaaca tggtggtaac ttaccgaaca aagccaaact aaaaaaaatt
      661 gcagacattg cgaattgtag tgtagaagat ttgctttttg atgaaggctt tatttctgaa
      721 aaatcccaag ttaaattgat aaatgaactc aaagaagaaa attcaaagct aaaagaaaaa
      781 ataaaatact atgaatgttt atttgatggt atagagagtc tgctgaactc acgaaaaaat
      841 tcctagttaa ttaaactaga gtaaaattat ttgtaggtgt taaatatgtt agttggctat
      901 gcacgagtca gttcagatga tcaaaatttg gaaagacagc ttgaagaatt tagaaaaatt
      961 ggtgtcgaaa aagtatttgc tgagaaaaaa tctggacgta acacagtaga acggccagag
     1021 ttcaataaaa tgttgtcatt tgtcagagaa ggggatacgc ttgtttttga gtcgcttgaa
     1081 cgcttaggaa gaaattctga tgaaatacta gaaacagtat cttttataga taaaaatggt
     1141 atgggcttaa tggttttgaa tttaccaatt ttagatacaa aatttggtga tccaaactta
     1201 gaaaaacttg ttagaagctt agtaattaac attttttctt ggacggctca aaatgagagg
     1261 gaggaaatta agagaaaaca aaaacaagga atagcaattg cgaagaagaa aggagtctat
     1321 aaaggaaaac cctacgaata ttcttctact gcaaagaatc cacaaaagag gtttatctat
     1381 aatgaaatag taagaatgct tggagaaggt gttccgatta agcgaattgc agaaaaaaca
     1441 ggaacaaata gaaatttagt ctatagaata aagaaaagaa taagtgaatc tgattgattt
     1501 taagttcttt gagaaatcaa tgttacgaga gaaggattct aagcctgttt caaactt
//
LOCUS       DAXLPQ010000151         1523 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.159, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000151 DAXLPQ010000000
VERSION     DAXLPQ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.159"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..1217)
                     /locus_tag="ACF3UO_002846"
     CDS             complement(<1..1217)
                     /locus_tag="ACF3UO_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658759.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
BASE COUNT          554 a          230 c          173 g          566 t
ORIGIN      
        1 aaaatcttaa tcggtttaac atttgttaaa aataaatcat aataatctaa cacataataa
       61 taatccaaaa ataattgtgc ccagttttct aatttctttg atacatccaa atccgcattt
      121 gcttgtaatt cttttttgag tttttccatt atgtgataag ttcgaggttc ttcttctttc
      181 atttcttcga tatacgaacg attaaaaaaa agatctggat taccataaaa tagataactt
      241 ctttcatgaa atgcaataaa attgaatatg agttctggat cctttatatc taaagaaaaa
      301 cggaacatgc tttgtaaaac tttctccaaa ttctcaactg ctcgataaga acaagtattt
      361 tgtcgctgat gtgcatatgc atgactattt tcatatattg catttccatc aattactcca
      421 aaagaataaa ttattcgata aaggaaacac agttcatcgc tgttaaaaga aagattgatt
      481 tgttttgacc acttcttcaa aagattaaaa tgcggatcat ctgagataac tgatttatat
      541 tcattatcta ctcgtacttt tctaaatgaa cttctttcta tattaatggc taaccaaaaa
      601 gaaaatacac gtttttgaaa aatagttaac gtaatatcat aaatcccctc aaaagcaact
      661 atatacttct ctatttcctt ttgttcgata tgaaatggcc acttatcact actttcacgt
      721 gtagaattcc aatagaaata ataaaaaaag ctacgaatgt ttgcctctga tgcattcaat
      781 tctaactgaa atggatgaaa tgttatatga taacgcctaa aatatggaat taagagcttc
      841 gcatatctga aaacagtaga tacactagta aattgctctt tagcaaaatc ttttagaaca
      901 cttctaggat atttatacat aaaatcaatc aaatgataat tataagaagc tttataaaaa
      961 tgaagataaa tattataaat aggaaaatct ttctcttttt ttatgaaaaa tcgtttatta
     1021 tcttcatttt tcagaaggat attaccatta tattgcttaa ataaatcctc tagttcttct
     1081 atatagtgta agactgactt ctccgtaaca ttaagtaaat ttctaagttc ttccattgca
     1141 caccaattgt ctttttctaa caaataatct aataaaacta cttttttgaa agatgtttta
     1201 gttaaaaaag tttgcatcat ttcacctcaa taagttactt ttgtttattt taatcaaaga
     1261 ataaacttct ctcgttcgac tataactgat cgaacaaaag aagcctttta ataaatataa
     1321 tctcacttac atacataggc tagttatttg cttctagctt atgataagta tataaacgga
     1381 tatcgatttc ataattgttt tatcttaaac atcatagctg taattgtttt tatttttaca
     1441 tgaagaatta ttataatcta gtttaatttt tttctgaaat atagaataaa aataaaaaca
     1501 tcttttcatt ttgagttatt aat
//
LOCUS       DAXLPQ010000152         1498 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.160, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000152 DAXLPQ010000000
VERSION     DAXLPQ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.160"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..381)
                     /locus_tag="ACF3UO_002847"
     CDS             complement(<1..381)
                     /locus_tag="ACF3UO_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3658760.1"
                     /translation="MRKWKVVVGSLGILIALFILGACSTNSKDKVASNEKLKVVVTNS
                     ILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGGNA
                     WFTKLVKNANKEENKDYFAASDGID"
     gene            complement(381..1223)
                     /locus_tag="ACF3UO_002848"
     CDS             complement(381..1223)
                     /locus_tag="ACF3UO_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFD3658761.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAMGMNVNFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISAAVGASSSLLGLFIGYNFNIAAGSSIVLTAASLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(1225..>1498)
                     /locus_tag="ACF3UO_002849"
     CDS             complement(1225..>1498)
                     /locus_tag="ACF3UO_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3658762.1"
                     /translation="QNADFIFLDEPFVGIDLISERIIMDTLKELKNQGKTVLIVHHDL
                     SKVKKYFDNIILLNRNVIAHGSVESVFNEENLKKAYGDTIFIGERE"
BASE COUNT          533 a          292 c          175 g          498 t
ORIGIN      
        1 atctatgcca tcacttgctg caaaatagtc tttgttttcc tctttgttcg catttttaac
       61 taattttgta aaccaagcat ttcctccagt ttccaagtta acaccattat aaaaaatcaa
      121 gtctgctttt gaagtttttt gaacatcttc aggcaaaggt tcatattcat ggggatcttt
      181 cccaataggt acaatactgt gtaaatcaat tttatccttt gctatatttt cagtaatatc
      241 tgctaaaatc gaattagtaa ctactacttt taatttttcg ttcgaagcca ctttatcttt
      301 actatttgtt gaacacgctc ctaatataaa aagagcaatc aaaatcccca gacttcccac
      361 tactactttc cattttctca tcataacgat ctctccttct ttcttaaaaa tttttgtttt
      421 ggtgagatta gaaaactaat tacaaataag gatgccgctg ttaaaacaat acttgatcct
      481 gcggctatgt taaaattata accaataaac aatccaagca atgatgagct tgccccgact
      541 gctgcagaaa taaatatcat agttttcaag ctatttgcat ataaatatgc tgtagctgct
      601 ggcgtgatta acattgcaac aattaatata gtccccacac tttgcatagc tgttactgct
      661 actaaagtta atagaaccat cagtagataa tgataaaaat tgacgttcat ccccattgct
      721 tttgccatta atggatcaaa agaagtaatt aataattctt taaaaaatag aactactata
      781 accaacacta aaacagaaac gccaatcgta atccacttat caatatcttg tacagctaaa
      841 atgtttccaa ataagatatg aaataaatcc gttgagctat ttgcaactcc tataaggata
      901 actcctagcg ctaaaaaaga actgaaagta ataccaattg ctgtatctcc ttttattaca
      961 ctattgcttt ttataaaagt aataatgata gaagctaata gaccaaatac aatagcacca
     1021 ataaaaaaat taatacctaa aatataagaa attgctactc ctggcaaaac agcatgagaa
     1081 atagcatcgc ccataagaga cattcctctt aaaataataa aacaacctac tgttccagaa
     1141 acaatcccta taactacaga tgtaattaga gcattctgta aaaagtgaaa gtcatacaga
     1201 ccattaataa aattttgaag catgttattc cctctctcca ataaatatag tatctccata
     1261 ggcttttttt aaattctctt cattaaatac agattctaca cttccgtgag caattacatt
     1321 tcgattcaaa agaataatat tatcaaaata cttctttacc ttgcttaaat catgatgcac
     1381 aattagcact gtttttccct gatttttcaa ttcttttaac gtatccataa ttattcgttc
     1441 actaattaag tctatcccta caaatggttc atctaaaaat atgaaatccg cattttga
//
LOCUS       DAXLPQ010000153         1485 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.161, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000153 DAXLPQ010000000
VERSION     DAXLPQ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.161"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            850..>1485
                     /locus_tag="ACF3UO_002850"
     CDS             850..>1485
                     /locus_tag="ACF3UO_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFD3658763.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFS"
BASE COUNT          490 a          245 c          250 g          500 t
ORIGIN      
        1 cgaaccgcca caagccacca aataaattcc agaaatctct ccatcatttt tttctacaat
       61 tgcgttaacc gtttttgcta catccatcaa catttcctcc ttaaaatttt aaaaatgtta
      121 attttatcca aaataaaagt aactgattaa atgtaaagat atcacataac gtcatataac
      181 gtcatgtgac ataattgcat tgtatccgct ttctttgtgt ttgtcaatag gaaaaattta
      241 tttctctaaa aaatataaat aatctgcagt gaaacttgag tacatatact aatttcgaaa
      301 aatgcctatg atttaaataa ttatggtgct gggatgaagg tttataagtt tgtcttgatt
      361 tgtttagaag aaatcgtttt tgcacacagt tgaattagga aactactgga gtggaaaata
      421 aagtgatttg acgggtagat gggtgcactt aaatttgaaa atggcttaaa atgctttatt
      481 ttgaattgca gaatttcttt tagtacgcaa tttatggtct taaaactgat taaaaagtga
      541 tacattgatt ttaatacaat ttatgataca aaaaatgacc tcctttctta aataaaagag
      601 gtcattttgt tttgtctcat aatcgattgt ttttgataca gtagttatat tcagaaaaaa
      661 taaagactct tctgagttta taatcctttg gattatatac ggatacagat gtagacataa
      721 aacaagctca attttcaaaa atggcattac tcaccttttt ggtgaattat ttgtataaaa
      781 aaaatataga aaagacaccc tgaaatcctt tagaattaat ttggctacca attcatagga
      841 ggattcaaga tgtctcatac tcagcttatc aaagataccc taaatattct agacctaaat
      901 atctatttcg aggaaaattg tttaactaaa gaaaaataca aagggcaaat ttgcttgatt
      961 tacaaaggaa ctcttctgta caagccagaa gagtgttccc attgtctttg tgtcgtcccc
     1021 tctaggatca ttcgttgggg gacgacaacc gttcggttgt tactgaatga tgtgtctgag
     1081 tatcgcactt atctggagct gaagaaacaa cgatttaaat gtaagtcttg ccaaagaaca
     1141 ttcgtagcgg atacctctgt tgctgaaaaa cactgtttca ttagtcaaaa agttcgttgg
     1201 tctgtcattg ctcgcttaaa agagaatact tccatgacgg aaatcgctcg tcagaaaaat
     1261 atttccactt cttcggtcta tcgtgtcatg aagcgattct accgcccatt gaatcctttc
     1321 aaacagactt tgccaaaggt cttatgcttt gatgaattca aatcggttcg aagtgttgcc
     1381 agtgcaatga gttttatcat gatggacgga caaagccatg cattattgga tattgtcgaa
     1441 aatcgacgct tgccttattt agaacgctat ttttctcggt tttca
//
LOCUS       DAXLPQ010000154         1449 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.162, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000154 DAXLPQ010000000
VERSION     DAXLPQ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.162"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>1449
                     /locus_tag="ACF3UO_002851"
     CDS             <1..>1449
                     /locus_tag="ACF3UO_002851"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFD3658764.1"
                     /translation="IRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQ
                     QKGVQGTFSLGRVQTPTLYLIFQRQEAIENFKKEPFFEVEASIKVNQGSFKGVLSPTQ
                     RFKTQEELLAFVSSKQAKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKAT
                     ASQTLKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPR
                     KRYVDGSKVQEHHAIIPTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEET
                     KIQTKVADLLFQSIGKTPKQEGWKILFKQQTKEEKEDVQTLPLVIIGERAEVGVKSVE
                     KETQPPKAFTEGTLLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEY
                     IQVIKNKLVVTEKGKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFITNIK
                     KFIVHLLEAVPNDIEKLNFSDYQEQKEKEAEKS"
BASE COUNT          549 a          243 c          293 g          364 t
ORIGIN      
        1 atccgaagcg gttttcaaaa tttgcaacct ggaatgaatt actatccctt ttatcaagaa
       61 gcgcaaacac gccaaattgc cgattggttg atcggcatga acgcaagccc tttgtatacg
      121 ttaaatttac aacagaaggg cgtacaaggt acattttcac taggacgtgt tcaaacgccc
      181 accttatacc ttatttttca gcgccaggaa gccatagaga attttaaaaa agaacctttt
      241 ttcgaggtgg aagctagtat aaaagtaaac caagggtcgt ttaagggcgt tctaagcccc
      301 acacagcgtt ttaaaaccca agaggagctt ttagcttttg tttcttctaa acaagctaaa
      361 ataggcaatc aagaggggat aattgctgat gttcaaacca aagagaagaa aacgaatagt
      421 ccgagtttgt tttctttaag tagtttgcaa tcaaaagtca atcagcttta taaagcgaca
      481 gcgagccaaa ctttaaaagc tatgcaagga ctgtatgaag caaaattatt gagttatcca
      541 agaacagata caccatttat tacagagaac gaatttgctt atttaaaagc aaattttggc
      601 aaatatagcg gttttttagg acttgatctc gaaatggttc aaacagagcc tagaaagcgt
      661 tatgtggacg gtagtaaggt acaggaacac cacgccatta tcccaacaaa acaagtacct
      721 accgaatctg cattagcaaa aatggacgat ttacaacgaa aaatatatgc tttagtcgtt
      781 aaaacgaccg ttgccatgtt tttacctgat tacttgtatg aagaaaccaa gatacaaacg
      841 aaagtagctg atttgctgtt tcaatcgatc ggaaagacac caaagcaaga agggtggaaa
      901 attcttttca aacaacaaac caaagaagaa aaagaggacg ttcaaacgtt accactcgtt
      961 atcattggcg aacgtgccga agttggtgtt aagagtgttg aaaaagaaac gcaaccgcca
     1021 aaagctttta cagagggtac attattaact gctatgaaaa cggcgaataa aacggttgat
     1081 gatgaagaag caatcaagat tttacaagaa gttgagggga ttggaacaga agcgacaaga
     1141 gcaagtatta ttgaagcgtt aaaacaaaaa gaatatatcc aagtgattaa gaataagctt
     1201 gttgtaactg aaaaaggaaa attattgtgc caggcagttg aaagtcagca ccttttaacg
     1261 agtgctgaaa tgacggctaa atgggaaacg tatttaaaaa aaatcggtaa aagagaaggc
     1321 aatcaagaga actttattac gaatatcaaa aaattcattg ttcatttact ggaagctgta
     1381 cctaacgata tagaaaaact aaatttttct gattaccagg aacagaaaga aaaagaagca
     1441 gaaaaaagt
//
LOCUS       DAXLPQ010000155         1430 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.163, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000155 DAXLPQ010000000
VERSION     DAXLPQ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.163"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..1350
                     /locus_tag="ACF3UO_002852"
     CDS             <1..1350
                     /locus_tag="ACF3UO_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFD3658765.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
BASE COUNT          564 a          225 c          309 g          332 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa
//
LOCUS       DAXLPQ010000156         1393 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.164, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000156 DAXLPQ010000000
VERSION     DAXLPQ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.164"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            90..500
                     /locus_tag="ACF3UO_002853"
     CDS             90..500
                     /locus_tag="ACF3UO_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3658766.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            514..870
                     /locus_tag="ACF3UO_002854"
     CDS             514..870
                     /locus_tag="ACF3UO_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3658767.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          505 a          198 c          256 g          434 t
ORIGIN      
        1 tttttttttt ttatatttta ttagctaata attggtattt taaaaaaaat tactgtagaa
       61 ttggattata attaaaaagg agtgagaaaa tgataaaagt atatacttcg cctagctgta
      121 cttcctgtag aaaagcaaga gcatggttgc aagcgaatca acttgaattt gaagagaaga
      181 atatttttgc cgaaccgtta acagaaagtg agatcaaaaa gatcttggca gcgactgaag
      241 gaggagttca agatattatt tccactcggt cgaaaattta cgaaaagctg ggcatagatt
      301 ttaacgaatt aactttaaag caaatgatcg tcttattcaa agaatatcct tcattattga
      361 gacgacctat tttgattgat gaaaaaagaa tactaatcgg atttaatgaa gatgagatcc
      421 ggtcatttgt ccctcgtgaa attcgatgtg ttgccagaaa tctgatctat ttacaaaaca
      481 ataacatctt aaattcatag ggagggagcc ttcgtggaag tgaaagtcta tggatcagcg
      541 cactgtgtaa caagtctgaa ggcgaaacaa tggttagaac accatcaatt gccttatcaa
      601 tttgttgact tagaagaacg cgatctaagt acagaagaag cagaagaatt atgcagtttt
      661 gaagaagtgc aagcagaaca gctatttgcg acttggtctg aggcttttca caacattgcg
      721 attgaccttt cctgtgtagg aaaaaaacaa ctgatttttt tatgcacaca acataccaat
      781 ctcctcagac gtcctttgat tattatcgat gaagttctat ttattggata caatgagcag
      841 ttgatggaac agcttatctt aaataaatag actttaactg ttttaatcaa gtcactgagc
      901 atttcataca gttgtaacag tcgaacactt agcatcaagc gtgttatgtg ttcttttttt
      961 gactttattt ttctactata gagacatgct caatttatag agacatgctc aatttatgtg
     1021 gtcaaaattc aaatctaggt ggggatatag agttaaaaat atattgacat gtgtaaattt
     1081 acatgatata ttcatttctg ttgttttaag tagcaaagca ataaaatagt attttaaaaa
     1141 acatataaaa tagttgttga catgttggaa atgacatgat aagataactg agtcgttgaa
     1201 aaagaaccac ttgcgaagct tgattctatc gaaaaaaact tcaaaaaagt tcttgacaaa
     1261 taacaaacga taagttatga taaatgagtt gctgaaagat ttcgaaaaac gaaatcgaaa
     1321 aaaactttta aaaaagagtt gacaatcgct tgtctctctg atatgatata aaagttgcta
     1381 cggcagccaa aaa
//
LOCUS       DAXLPQ010000157         1362 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.165, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000157 DAXLPQ010000000
VERSION     DAXLPQ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.165"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            55..>1362
                     /locus_tag="ACF3UO_002855"
     CDS             55..>1362
                     /locus_tag="ACF3UO_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3658768.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFI"
BASE COUNT          529 a          158 c          233 g          442 t
ORIGIN      
        1 agtgttagtt aaagatgaat atacttttta tagaaaggaa aagaatgtaa ttaagtggaa
       61 aaaatagtaa ttattggttc aaaccattca gggctagccg cagctcgatt tctaaactta
      121 agcgattcaa attatgaagt tattctaatc gataaaaaat cagaaattag ttacttggaa
      181 tgtgggacat cgttatttat aaaaggagaa gtaagtaatt tagaagatct tttttatcaa
      241 aatagaatga cactaaattc tgagataaaa aagttatttc tagagacaga agttgacaaa
      301 attgatattc aaaataaaaa gattagttgt gtaaaaaaag atggtacaag attctctcaa
      361 gaatatgaca aagttatatt agctacaggt tcaaagcaaa ttatgctaga tataccgggg
      421 aataatttag ctaatatttt ttcgataaag aattttccaa atgcaaaaga gatttttaaa
      481 gctttggatg atagtactat taaaaaagta ggaattattg gagcaggata tattggagtt
      541 gaaattgctg aagccataag aaaaagaggg aaagaagtat atcttttcga tgttgcagat
      601 agagtgttgt cgacttatta cgaccgtagt ttttcagata aagttgaaga aatactatca
      661 aaaaatggaa tacatctttg tctatcagaa agtcctaaaa aatatttagg aagaaaaaag
      721 attgaaaaaa tagtcactac aagtggtacc caatactcta tggatatggt cgtacaagct
      781 ataggatttc tatctaatag tccaattggg gaaaaggaac tcttgagaga tgttagtgga
      841 gcatatctaa ctaatgaata ccagcaaaca aatataaaag atatatatgc tattggggat
      901 tgtgctacaa ctttttttac gtccattaat agaagtagtg ttgatttttc tatttctaat
      961 gctctaagaa cagcttatat tgcaactcaa catattaaca atcaagattt tacaccttct
     1021 ggttcccaat ttacaaatgg cttttctata tttaattaca atttttacgc agcaggtttg
     1081 aatttaaaaa cagcacgatt attaagtgag tctatagatt atatagaaat agaagatttc
     1141 attagacctg cttttttgag aaaaaatagt cgtgtaaaat taagaattag ctttgaaaaa
     1201 aatacaaaga gaatagtagg tgtacaactt tgtagtcaag aagatttatc tggactatta
     1261 tcaatgtttt ctcttgctat agaagaacaa attacattag acaaattgaa aatgttagat
     1321 tatttatttc atcctagttt tagccaaccc tataatttta tt
//
LOCUS       DAXLPQ010000158         1361 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.166, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000158 DAXLPQ010000000
VERSION     DAXLPQ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.166"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..486
                     /locus_tag="ACF3UO_002856"
     CDS             <1..486
                     /locus_tag="ACF3UO_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3658769.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
     gene            complement(693..1217)
                     /locus_tag="ACF3UO_002857"
                     /pseudo
     CDS             complement(693..1217)
                     /locus_tag="ACF3UO_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          445 a          254 c          260 g          402 t
ORIGIN      
        1 ttaaaggaag cgatcgatca aatcaagacg gctgtcttgt atcctcataa cggattaccg
       61 attttattga tgggtgtaag cggttcagga aaaacctttt tggcagaaaa aatttatgaa
      121 tacgccaagg aacaacaggt gatagaatca aatgctccat ttatcgccta taattgtgct
      181 caatacttta atttctcgat taacaagatc gtagaaaatt taacgatcct tgatgcaatg
      241 aaggttttga gattggtaca aaaggccgtc aaagaactcg aaaaactaat ggggatcgaa
      301 ttttcaaaca atcaattgtt cttgctttac atgcactgct gctcaatgat cgaacgtatt
      361 ttacgcaaag aaagtgtaga tgaacaagca gatatcaaag aatatattca aaaagaggga
      421 cataattatg aaatatcaaa atacccggct tacaaaacga agtttgaaag tactgtaata
      481 aagtaagatt taaataagca taaacaaggt aagaaccata ggggctgtgt caagtccaaa
      541 atcttgtgta aaaaggaaat ctcaaagtac gatgttttgc cttgttgagc ctagctacgg
      601 tccaatatgc tggtaagaag tgtcaagagc aaaaagcgaa gcgtctcttg atacttctca
      661 ccagtatatt atactattgg cggcttaatg tgctaaatct cgttacgatc aaattcaaga
      721 tattttctag gtgcagaagt ccattcgtca tccttttcca tcaataaagc accgatgata
      781 cgaataacag aatcacaatt tgggaaaatt cggacaacac gttcacgacg gcgtacttct
      841 tcatttagtc tttcaagaac attcgttgtt ctcaatcgtt gacggatatt ttctggtaaa
      901 accattactt gcatggcatc ttcgaagccc tcatccaata ttttacaggc agttgcgact
      961 ttcttgtctt ccccatattt atccataata agttgtttac gttctccagc cagctcgatg
     1021 cttgccgttt tgaagatggc tttaaagtct tctttgatat cgcttgagat tttcttggag
     1081 aatttgtcgg aaatgttgcg aaggagatgt gcttggcatc tctgctagct cgcacaaaga
     1141 aggtattctt tcacagcttt tgtgagccct atatgcgcat ccgagatgac catctttact
     1201 cctgaaagac cgcgttcttt caatccgaga gtgtaaaata ttttgtgtaa atagaaaaaa
     1261 ggaagtccct tcagtagaat agagttacca caacacattc acagaaaaga ggacttccat
     1321 atgaacgatt ttactacaga aattctaaag actctagcga a
//
LOCUS       DAXLPQ010000159         1356 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.167, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000159 DAXLPQ010000000
VERSION     DAXLPQ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.167"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            78..>1356
                     /locus_tag="ACF3UO_002858"
     CDS             78..>1356
                     /locus_tag="ACF3UO_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFD3658770.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQ"
BASE COUNT          462 a          262 c          257 g          375 t
ORIGIN      
        1 taggtattaa aaaacatatc gttctctagt atgattaaat caccacaaaa taaacaactg
       61 agaggacgat acgctatatg aatgattcta tcaaaaaaat gctgagaata acagagaaag
      121 atttgatgat tacagaggtc tcttacgaga cccttcagaa gaaaaagacg ttggtcgtcg
      181 atgctgttct ctcgcctact cctcgtgctt gtagaagttg tggttctact gtggtagatg
      241 gaaacgggaa agcaattata gtgaaaaatg gaaaaaagga aacgattgtc cgttttgaac
      301 aatacaatca tatgcctttg gttatgcgcc taaaaaagca acgctatacc tgtaaaaact
      361 gtcgcaccca ttggacggct caaagttatt ttgtccaacc cagacattca atcgcaaatc
      421 atgttagata taaaattgct tctttactga ctgaaaaagt atctttatct tttattgcga
      481 aaagctgtca ggtatctttg accaccgtta ttcgtacatt gaaagagttt aaaagctatt
      541 taccaaagca atctaagaag atcctcccca gagtattgat ggttgacgaa tttcgttcgc
      601 atgcttccat agaagataag atgagcttta tttgcgcgga tggcgaaaca ggaaaattaa
      661 tagatgtttt gcctacgcgt aaattacctc gattaacaag ctatttctta ggttgtacca
      721 atccagaaga agtagaattc ttggtgacag acatgaacgc cgcctacttc cagctcacca
      781 aacgtgttct gccaaatgcg aaagtcgtga ttgatcggtt tcatattgtc aaacacatga
      841 atcaagcgtt caatgagttg cgtatccgtg aaatgaatga acttcgtaaa gccggacaga
      901 aaagccaggc agaaaaactg aaaaagaact ggcgcttttt gctaaaaaat cgtgcaaaca
      961 tcaaccatta tgaatacaaa acatggaaaa gtttccgagc accaaaatac ccatttctta
     1021 ctgaagcaat gatgattgat cgattgcttg agttttctcc gcccctaaag gaggcgtatc
     1081 ccttttttca tgaattagtt gaagcctttc gagacaaaga ccctgactta tttttctcct
     1141 tattggcaga acttcccgaa acgttagatg acagctttcg ggaaaagctt caaaaccttc
     1201 tgacctatga agaaggcatc accaacgcaa tgatctatcc ttattccaat ggaaaaatag
     1261 aagcgaagaa tacccacata aagacaatga aacgagtatc ctacggattt aaatcatttg
     1321 agaacatgag aattagaatc tttttgatca atcaat
//
LOCUS       DAXLPQ010000160         1282 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.168, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000160 DAXLPQ010000000
VERSION     DAXLPQ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.168"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            81..1253
                     /locus_tag="ACF3UO_002859"
     CDS             81..1253
                     /locus_tag="ACF3UO_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFD3658771.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          478 a          235 c          227 g          342 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
      901 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
      961 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
     1021 tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc cacaatcgac
     1081 taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga gaaaagatta
     1141 ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt cttatggacc
     1201 tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag tagaaatggt
     1261 aaaaacattg tatagcattt ta
//
LOCUS       DAXLPQ010000161         1270 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.169, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000161 DAXLPQ010000000
VERSION     DAXLPQ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.169"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(44..220)
                     /locus_tag="ACF3UO_002860"
     CDS             complement(44..220)
                     /locus_tag="ACF3UO_002860"
                     /inference="COORDINATES: protein motif:HMM:NF021542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3658772.1"
                     /translation="MKEFIEKYKYPLIFACVGLLLGLLILTLGLFKIVIITILTVCGF
                     YLGIYLETIGFFDK"
     gene            complement(230..790)
                     /gene="amaP"
                     /locus_tag="ACF3UO_002861"
     CDS             complement(230..790)
                     /gene="amaP"
                     /locus_tag="ACF3UO_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3658773.1"
                     /translation="MRKSLKLLLTIVLLLFFFPLAHTLITMQSVVSLPFYLLPFTSYP
                     YIGNNMAQFLFWLSAVLLTFLFIILIIVLFYPRINNYIEKKTDTGKIAIQKKAIENFV
                     LIAAKEEPFIVDPTVKVVIKKKKIKIYVRGKIRKAFQTGERQTSFIRKVNTNLNALFG
                     AEQTILTEIKFNDYHERNKETKSKVL"
BASE COUNT          460 a          188 c          136 g          486 t
ORIGIN      
        1 ataaaaattt attttttacc gtaaaaacgg ttattaacta gttttatttg tcaaaaaatc
       61 caatagtttc taaatagata cctaaataaa aaccacatac agtaagtatt gttattatca
      121 ctattttaaa aagtcctaac gtgagaatta ataatcctaa tagtagtcct acacatgcaa
      181 aaatgagcgg atatttatat ttctctatga attctttcat tgttttctcc tataaaactt
      241 ttgatttggt ttctttattt ctttcatgat aatcattgaa ttttatttca gttagtattg
      301 tttgttctgc accaaataag gcattcaaat tagtgtttac tttccttata aaggaggttt
      361 gtcgctcccc tgtttgaaaa gctttacgta tttttccccg tacatagatt tttatttttt
      421 tcttcttaat tacaactttt accgttggat caacaataaa aggctcttct tttgctgcga
      481 ttaatacaaa attctcaatt gctttttttt gaattgctat ttttccagta tcggtctttt
      541 tttctatata attatttatc ctaggataaa ataatacaat aattaaaata ataaataaga
      601 atgttagcaa aacggcacta agccaaaaca aaaattgagc catgttatta ccaatatatg
      661 ggtaacttgt aaatggtagt aaataaaatg gtaaactaac cacactttgc attgtaatta
      721 acgtatgtgc taaaggaaaa aaaaacagca gtaaaacaat agttaatagt agtttcaagc
      781 tttttcgcat attccacctc ttagattacg ttgtgaatat aattctttat tttattattc
      841 tatggaactt tacaattaaa caaaacctat aaattaaact tgacacagat tttggcagtt
      901 tgatttctag aatattctcc tttcatttca tttatctcac taactttagt taaactaata
      961 cgataagttt aaccaattac tatatctgaa actatcaaag tgagtaactt gtataaaaaa
     1021 atagactgtt cactttataa attaaaatag tttacgatat aatattatca agtaaaaatc
     1081 ctcaagtcaa ataaaaatga atgttcaatt tattttttat acaagttttt taattctaga
     1141 aataagttcc ctgcttataa gaagatgtac taaataatga ttcttatctc acaaacatat
     1201 tatttcttac ctccaatcct tttagaaacc ataaaaacta ttaactaaca atatttgaaa
     1261 attcacacta
//
LOCUS       DAXLPQ010000162         1246 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.170, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000162 DAXLPQ010000000
VERSION     DAXLPQ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.170"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            200..742
                     /locus_tag="ACF3UO_002862"
     CDS             200..742
                     /locus_tag="ACF3UO_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658774.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="ACF3UO_002863"
     CDS             898..>1246
                     /locus_tag="ACF3UO_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFD3658775.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAXLPQ010000163         1208 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.171, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000163 DAXLPQ010000000
VERSION     DAXLPQ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.171"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            2..1208
                     /locus_tag="ACF3UO_002864"
                     /pseudo
     CDS             2..1208
                     /locus_tag="ACF3UO_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          503 a          193 c          263 g          249 t
ORIGIN      
        1 catggcagaa gaaaaagaac cactagacaa tagtcgtttg ggaaaatcca aaagaaaatt
       61 agtacgattg caaaatgaat taaacgaaca aattgaaaag atgtttgaac accagagaaa
      121 gaccaacggt caaccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga
      181 gcgaatcgaa aataaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaagt
      241 agaaaaactt gaaagacaag aagagataaa ggaaatgggc tataacaagt acggcggact
      301 ggatatgacg atcgagaata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg
      361 tgaatcgact ttttcagccg ctacgatccg aaaataccaa cggaaattgg aaacattaga
      421 acagctgaaa gaaagatcgg aaaaaggaaa agaaaacctt cttcctgaag tacaagcaat
      481 cattgacagc ggacgagtga cgcaatggaa aaaaatccga ccatttattt tctgaaaggc
      541 tatcgaaaag tcgctttaga actgaatgaa aacggggaat ttgaggaatc taaaaaatac
      601 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgtacca
      661 actgattttt tgaaggagaa agaaaacgat catttttatc gagtagaatt caacgaaaat
      721 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacattcga attgatcgat
      781 caactcaaaa cgttggataa ccaatacgcc gcagaagcag gttattataa attctatttt
      841 gaagaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
      901 aacagtaatc aacccatcta tttagagtta gcaaaattgt gcgaacaagt acctgagaag
      961 gaacaaaaac aatcggtcaa aaatgaacct gtttcgaaag aacaaatgca gtcgaaagaa
     1021 acaaaaacaa aacaaaaggg ctatcaaaaa cgaacggcag aagagattaa acaagaagtt
     1081 aaatcccttt cgcaacaggc actggatgcg gtgaaaaagc atactcattc tcctgaagac
     1141 gtcaaagaac ttttgaactt tatgtctcgt tttccagaac gatcctttag aaatcaatta
     1201 ttgattga
//
LOCUS       DAXLPQ010000164         1190 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.172, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000164 DAXLPQ010000000
VERSION     DAXLPQ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.172"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            143..400
                     /locus_tag="ACF3UO_002865"
     CDS             143..400
                     /locus_tag="ACF3UO_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658776.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="ACF3UO_002866"
     CDS             complement(632..1063)
                     /locus_tag="ACF3UO_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HFD3658777.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          438 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc
//
LOCUS       DAXLPQ010000165         1133 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.173, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000165 DAXLPQ010000000
VERSION     DAXLPQ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.173"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>1133
                     /locus_tag="ACF3UO_002867"
     rRNA            <1..>1133
                     /locus_tag="ACF3UO_002867"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          290 a          256 c          350 g          237 t
ORIGIN      
        1 agagaatcct aaggtgagcg agagaactct cgttaaggaa ctcggcaaaa tgaccccgta
       61 acttcgggag aaggggtgct gatcatacga tcagccgcag tgaataggcc caagcgactg
      121 tttatcaaaa acacaggtct ctgcaaaatc gtaagatgaa gtataggggc tgacgcctgc
      181 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtacgaat tgaagcccca
      241 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
      301 ccgacccgca cgaaaggcgt aacgatttgg gcactgtctc aacgagagac tcggtgaaat
      361 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
      421 actgtagttt gatattgagt gtctgtaccg catgtacagg ataggtagga gccgtagaaa
      481 tcggaacgct agtttcgatg gaggcgctgg tgggatacta cccctgcgtt atggccactc
      541 taacccgcac cactaatcgt ggtgggagac agtgtcagat gggcagtttg actggggcgg
      601 tcgcctccta aaaggtaacg gaggcgccca aaggttccct cagaatggtt ggaaatcatt
      661 cgaagagtgt aaaggcagaa gggagcttga ctgcgagacc aacaagtcga gcagggacga
      721 aagtcgggct tagtgatccg gtggttccgc atggaagggc catcgctcaa cggataaaag
      781 ctaccctggg gataacaggc ttatctcccc caagagtcca catcgacggg gaggtttggc
      841 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
      901 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
      961 cgtcgcgggc gttggaaatt tgagaggagc tgtccttagt acgagaggac cgggatggac
     1021 ttaccgctgg tgtaccagtt gttctgccaa gggcattgct gggtagctat gtagggaagg
     1081 gataaacgct gaaagcatct aagtgtgaag cccacctcaa gatgagattt ccc
//
LOCUS       DAXLPQ010000166         1091 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.175, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000166 DAXLPQ010000000
VERSION     DAXLPQ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.175"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="ACF3UO_002868"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="ACF3UO_002868"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFD3658778.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAXLPQ010000167         1076 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.176, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000167 DAXLPQ010000000
VERSION     DAXLPQ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.176"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            3..>1076
                     /locus_tag="ACF3UO_002869"
     CDS             3..>1076
                     /locus_tag="ACF3UO_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3658779.1"
                     /translation="MGACSSTNDAKVSNDKDGKLEIVTTFYPMYDFTKNIVGDEANVD
                     LMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKAKESWKKAGPNVVEGTK
                     DMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNIKDQLVKLYPKKAKVFE
                     TNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALDYGLKQVPIAGLSPEEE
                     PSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIKLEVLNPLESLTKEQMD
                     NGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANGYFKDADVKDRELSDYT
                     GEWQSVYPLLKDGILDEVFDYKAK"
BASE COUNT          406 a          152 c          239 g          279 t
ORIGIN      
        1 tattgggagc ttgctccagc actaatgatg caaaagtatc gaatgataaa gatggaaaat
       61 tagaaattgt aacaacattc tatccaatgt atgatttcac caaaaacatc gtcggcgatg
      121 aagcgaacgt ggatttaatg gttccagcgg gatcagaacc tcatgactat gagccctcag
      181 ctaaggatat ggcaaaagct catgatgctg atgtttttgt atatcataac gaaaacatgg
      241 aatcatgggt accaaaagct aaagaaagtt ggaagaaagc tgggcctaat gtagtagaag
      301 gaacaaaaga catgatttta ttgccaggta gtgaagaaga agatcatgat cacggagaag
      361 aagatcacca tcatgaacta gatcctcata cgtgggtttc acccaaaatg gcaattaagg
      421 aagtttcaaa tatcaaggat cagttagtta aattgtatcc gaaaaaagca aaagtatttg
      481 agacaaatgc tgaaaagtat ttgactaaac tgaaacggtt ggatgctgac tataccacta
      541 gtcttaaaga agcgaaacaa aaaagttttg tgacgcaaca cgcagccttt ggatatttag
      601 ctttggatta tggattgaaa caagttccta ttgctggact aagtcctgaa gaagagccat
      661 cttctggtcg attagctgaa ttaaaagagt atgttaaaaa aaataagatc aattatattt
      721 actttgaaaa gaatgctaat gataaaattg caaaaacttt ggccaacgaa gctgggataa
      781 aattggaagt actgaatcct cttgaaagtc ttacaaaaga acaaatggat aatggtgaag
      841 attatgtttc agtaatggaa gacaatctaa aagcgttaga aaaaacaact atggttgctg
      901 gtgaagaggt agttccagaa aaagaagcga aggatgaaaa gacagttgct aatgggtact
      961 ttaaagatgc cgatgtgaag gatcgcgaat tgagtgatta tacaggcgaa tggcaatctg
     1021 tttatccgtt gttaaaagat ggaattttgg atgaagtttt cgattacaaa gcaaaa
//
LOCUS       DAXLPQ010000168         1063 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.177, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000168 DAXLPQ010000000
VERSION     DAXLPQ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.177"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(37..>1063)
                     /locus_tag="ACF3UO_002870"
     CDS             complement(37..>1063)
                     /locus_tag="ACF3UO_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFD3658780.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          178 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aac
//
LOCUS       DAXLPQ010000169         1021 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.178, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000169 DAXLPQ010000000
VERSION     DAXLPQ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.178"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            179..420
                     /locus_tag="ACF3UO_002871"
                     /pseudo
     CDS             179..420
                     /locus_tag="ACF3UO_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            469..552
                     /locus_tag="ACF3UO_002872"
     CDS             469..552
                     /locus_tag="ACF3UO_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFD3658781.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            677..>1021
                     /locus_tag="ACF3UO_002873"
     CDS             677..>1021
                     /locus_tag="ACF3UO_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFD3658782.1"
                     /translation="MKKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVF"
BASE COUNT          422 a          134 c          170 g          295 t
ORIGIN      
        1 attggggaaa agggatatat tgattttata tctttctcaa aataaacata aaagcccttt
       61 aaagagggct tttatatatt aatcacaaat cacttatcac aaatcactta tcacaaatca
      121 caagtgattt gtgattgttg atgataaaat aagaataaga agaaatagaa agaagtgagt
      181 gattgtggga aatttaggcg cacaaaaaga aaaacgaaat gatacaccaa tcagtgcaaa
      241 aaaagatata atgggagata agacggttcg tgttcgtgct gacttgcacc atatcataaa
      301 aatcgaaaca gcaaagaatg gcggaaacgt aaaagaagtt atggaaataa gacttagaag
      361 caaacttaag agtgtgttga tagtgcagta tcttaaaatt ttgtgtataa taggaattga
      421 agttaaatta gatgctaaaa atttgtaatt aagaaggagg gattcgtcat gttggtattc
      481 caaatgcgta atgtagataa aacatctact gttttgaaac agactaaaaa cagtgattac
      541 gcagataaat aaatacgtta gattaattcc taccagtgac taatcttatg actttttaaa
      601 cagataacta aaattacaaa caaatcgttt aacttctgta tttgtttata gatgtaatca
      661 cttcaggagt gattacatga aaaaaaatat aaaatattct caaaactttt taacgagtga
      721 aaaagtactc aaccaaataa taaaacaatt gaatttaaaa gaaaccgata ccgtttacga
      781 aattggaaca ggtaaagggc atttaacgac gaaactggct aaaataagta aacaggtaac
      841 gtctattgaa ttagacagtc atctattcaa cttatcgtca gaaaaattaa aactgaacat
      901 tcgtgtcact ttaattcacc aagatattct acagtttcaa ttccctaaca aacagaggta
      961 taaaattgtt gggagtattc cttaccattt aagcacacaa attattaaaa aagtggtttt
     1021 t
//
LOCUS       DAXLPQ010000170          945 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.181, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000170 DAXLPQ010000000
VERSION     DAXLPQ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.181"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            36..>945
                     /locus_tag="ACF3UO_002874"
     CDS             36..>945
                     /locus_tag="ACF3UO_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658783.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPM"
BASE COUNT          338 a          173 c          182 g          252 t
ORIGIN      
        1 agttccgacg aaagaattat aaggagtgag tacaaatgac ctataaccat cttacaccaa
       61 ctgaactcgt aatgatagaa gcttatttca atcaatcaca acctgtttca aaagtagcca
      121 atctgttaca acgttctcga caaactattt ataaggtcta tcgttttctt aaatctggtg
      181 gaagcgcaat gagctactat aaacaatata agaaaaacaa acgtaactgc ggaagacatc
      241 cgattgtttt acctgatgag caacaggaat acattcaaaa aaaggttgtt caagggtggg
      301 ctcctgatgt ccttattggt cgagcagagt ttcctattgc ttgttcggta cgcacactgt
      361 atcgaatgtt taaagataaa acctttgaca ctcacgattt accaatgaag ggaaaaagaa
      421 aaccaaacgg tcataaagaa aaaagaggaa aacaagggtt tcgccggtca atccgagaca
      481 gaaagacaga ctatacccag tttgatcatg aatttggtca cctggaaggt gacactatcg
      541 tgggtggaaa acataaaagc gcggtcatca cattagttga acggctatct aaagtcatca
      601 ttaccttgaa acccgaaggc agacaggcta aagacattga aaataggctg aatcaatggt
      661 ttcgttgtgt cccaaaaaac ttatttaaat ccatcacatt tgattgtgga aaagaattct
      721 caaattggaa aaagattagt aataccaacg atatttcaat ttattttgcg gatccaggaa
      781 caccttctca acgaggattg aatgaacatt caaatggctt attacgtaaa gatggtttgt
      841 ataaagctat ggattttaat ggtgtatctg aaacctttat ccaatcggtg gcatcgaaac
      901 gaaatcatat tcctagaaaa tcattacact atcggacacc aatgg
//
LOCUS       DAXLPQ010000171          944 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.182, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000171 DAXLPQ010000000
VERSION     DAXLPQ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.182"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            160..693
                     /locus_tag="ACF3UO_002875"
     CDS             160..693
                     /locus_tag="ACF3UO_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658784.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            705..908
                     /locus_tag="ACF3UO_002876"
     CDS             705..908
                     /locus_tag="ACF3UO_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658785.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKSKKK"
BASE COUNT          323 a          122 c          184 g          315 t
ORIGIN      
        1 aatataacat attttcctaa tgcattctaa ctataccaca ttatcaaaaa tataaattat
       61 ctttactaaa taaaatattg acaagcctat accttttgtt ttatgatttt cacaaagaaa
      121 acgttttcta tatatttttc tgtatcagga ggaaattcta tgaaaaaatt tactttaggg
      181 gtagctttgt taactattgg ggcagttgtt ttaccgtcaa ctactatagt ttatgcttca
      241 gaaaattccc aagtggtatc attaaacgaa aacaatgcta ctgaaaatgt agttattgag
      301 tacactgaag atggtatggt cgtaactaaa tatgaggatg gttatagtgc ggaagatttt
      361 gcaaattctt cagatatcat gacaagagct gcagttgcaa gatggggcaa aaaggaatat
      421 acaaatattg ctgtaaccac tggagtagct gctaatgcta ttaatgctgc cttttgggca
      481 ggagggaaag ctagcacttc tatgtttggt atcccaggtt gggcaattgg tgctttgtta
      541 acaggtgcaa gttggactaa aaaaggtgct tctccaggga atgcagttgc aaaagaatgg
      601 gacaaaaatg gtaatggctg gattggattt tattaccaaa ggggatatga tgcagctgga
      661 agagttgtag ctactagata ttcaacgtta taagttaagg agtgatgttt ttgatatcta
      721 aatcattaaa atcattaaaa acatttacta aaaagaatcc gcaaatagct actattcgta
      781 tttttatatt tgctatagct gttgctataa ttgttaatat gctaagcgga gggcaattat
      841 acaaatctgg tttattttta gtgttaatct tagttgtctt agacataata aagtctaaaa
      901 aaaaataaat cgatacattt tagaagaata gggttgtttg aata
//
LOCUS       DAXLPQ010000172          935 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.183, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000172 DAXLPQ010000000
VERSION     DAXLPQ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.183"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            26..>935
                     /locus_tag="ACF3UO_002877"
     CDS             26..>935
                     /locus_tag="ACF3UO_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658786.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPL"
BASE COUNT          330 a          174 c          178 g          253 t
ORIGIN      
        1 aaagaattat aaggagtgag tgcaaatgac ctatacccat cttacaccaa ctgaactcgt
       61 aatgatagaa gcttatttca atcaatcaca ctctgtttca aaagtagccc atctggtaca
      121 acgttctcga caaaccattt ataatgtcta tcgttttctt aaatctggtg gaagcgcaat
      181 aagctactat gaacaatata agaaaaacaa acgtaactgc ggaagacgtc cgattgtgtt
      241 accagatggg caacaagaat acattcaaaa aaaggtggct caagggtgga ctccagatgt
      301 ccttattggt cgagcagagt ttcctattgc ttgttcggta cgtacactat atcggatgtt
      361 taaagataaa acctttgacc ctcacgattt accaatgaaa gggaaaagaa aaccaaacgg
      421 acataaagaa aaaagaggaa aacaagcttt tcgccgttcg attcaggata gaacaactga
      481 ttatatacag ttcaatcatg agtttggtca cctagaaggt gacaccattg tcggtggaaa
      541 acataaaagt gcggtgatca cgttagttga gcgattatct aaagtgatca tcaccttgaa
      601 acccgctggt aggcaagcta tagatattga gaatagactg aatcaatggt ttcaatctgt
      661 accgaaacac ttgtttaaat ccatcacatt tgattgtgga aaagagttct cgaattggaa
      721 aaagattagt aataccaatg atatttcgat ttatttcgct gatccaggaa caccttctca
      781 acgaggacta aatgaacatt cgaatggctt attacgtaaa gatggcttat ataaagctat
      841 ggattttaat aaggtatccg aaacctttat ccaatcggtg gcatcaaaac gaaatcatat
      901 tcctagaaaa tcattacact atcgcacacc attgg
//
LOCUS       DAXLPQ010000173          906 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.184, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000173 DAXLPQ010000000
VERSION     DAXLPQ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.184"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            4..582
                     /locus_tag="ACF3UO_002878"
     CDS             4..582
                     /locus_tag="ACF3UO_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3658787.1"
                     /translation="MDNKTNNTKTEIKKNDISKASEAIKGELVFEDKVIQKIIGIALD
                     EIDGLLTVDGGFFSNIAGKLVNTDNTTSGVDVEVGKKQVAVDLSIVAEYGKDVTTIYD
                     KIKQVISNEVRKMTGLDVIEINVNVVDVKTKEQYEKDSVTLQDHLTDAASATGEFASK
                     QIEKSKEALGVASEKVNDGVQNVKEATEPRVK"
BASE COUNT          364 a          103 c          153 g          286 t
ORIGIN      
        1 ctaatggata ataaaacaaa caatacaaaa acagaaatta aaaagaatga tatatcaaaa
       61 gcttctgaag ctattaaagg agaattggtt tttgaagata aagtaattca aaaaataatc
      121 ggtattgcat tagatgaaat tgatgggctt ttgacagttg atggaggatt cttttcaaat
      181 atagccggaa aattagtaaa tacagataac acaacttctg gagtcgatgt tgaagtaggt
      241 aaaaaacaag ttgcagtaga tctttcaata gtggctgaat atggtaaaga tgtaactaca
      301 atttatgata aaattaagca agtaatctca aatgaagtta ggaaaatgac tggcttagat
      361 gtaattgaaa ttaacgtaaa cgtcgtagat gtaaaaacaa aagaacaata cgaaaaagat
      421 tcagttaccc tacaagatca tcttactgat gcagcttctg ctactggaga atttgcttca
      481 aaacaaattg agaaatcaaa agaagcttta ggagtagcaa gtgaaaaagt taatgatggt
      541 gtacaaaacg taaaagaagc aacagaacct cgtgtaaaat agtaacttcc tttctgtaat
      601 atacaacata taaaattgaa agactaaatt taaggctctt agatatttta atgtagatat
      661 agaagaaaga actgaaatat aataaaacca gttaggtata ggacttaact ggttttagtt
      721 tctttaagtg ggagatcaac atctgaataa gcattttgtg aaagatgtag aaatctttat
      781 agctgttggt tactcatttt gtatttctta tttagttctt ttgtctcttt ctagtaaatc
      841 tttacaatat tttagttctc aatttatatt atttaaaaat tttattatcg tataaaccat
      901 tataaa
//
LOCUS       DAXLPQ010000174          821 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.185, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000174 DAXLPQ010000000
VERSION     DAXLPQ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.185"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..734)
                     /locus_tag="ACF3UO_002879"
     CDS             complement(<1..734)
                     /locus_tag="ACF3UO_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFD3658788.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVR"
BASE COUNT          238 a          178 c          140 g          265 t
ORIGIN      
        1 ttgcgaacag ccttaactaa ccctttgtgt gcatcagaaa tgaccagttt tacaccgaac
       61 aaacctcgtt gaacgaacga ttgaaaaacg gtatcccaat tatcttccga ttcgccgtct
      121 tgaacatcaa aaccaagaat cgtacgtcgt ccatcagaat caatgccgat accaatatat
      181 acaccttttg agacaatacg atgattttcc cttactttca tatacagggc atcacacatg
      241 aaaaatggat attccgagcc ttctaggctc cggtttctcc actcaaaaac aaatggatcc
      301 aactgtttca tcagatttga aacgaatgat ttagaaacag tcgcaccatc cgttagcagt
      361 tcaactgttt tagttacttt gcgagtggag acaccagaaa tgaccatttc aatcatggca
      421 gcgatcaaag ctttttcgct tcgctgatat ctttcaaaga tagtaggact aaacttaccg
      481 tctctggttc gtggaacatg aagttctaac gtaccaattc gagttgtaaa cgaacgatcg
      541 tagtaaccat ttctttgtga ttgccgttct tctgaacgtt cataggcatt tgcctgaata
      601 tattgatttc gttgttcttc catcagctga ttaaacatga tagtcataag tgtttttgcg
      661 gtatcattcg caccgctttc gtttataatt gcttgaattt cttcgctttc aaaagtaaaa
      721 tgtacttgag tcattgatat cagtcctatt cgagtatgtt ttctgcaaaa aacattgtac
      781 tcctaactga gatcaatggc ttttttgatg cttcactttt a
//
LOCUS       DAXLPQ010000175          771 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.186, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000175 DAXLPQ010000000
VERSION     DAXLPQ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.186"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            347..745
                     /gene="spxA"
                     /locus_tag="ACF3UO_002880"
     CDS             347..745
                     /gene="spxA"
                     /locus_tag="ACF3UO_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFD3658789.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          289 a          107 c          137 g          238 t
ORIGIN      
        1 aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct taagaaatcg
       61 gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt tcatatgttt
      121 agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa gcgagaatgc
      181 tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat tatgaaaaaa
      241 aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt attatgatct
      301 tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt taacattata
      361 tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag aacatcagat
      421 tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat taaaagcgat
      481 tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca aagtattcca
      541 aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac ttgtgcaaaa
      601 caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc aagttggttt
      661 taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag aattacgtca
      721 agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag a
//
LOCUS       DAXLPQ010000176          728 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.188, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000176 DAXLPQ010000000
VERSION     DAXLPQ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.188"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..330
                     /locus_tag="ACF3UO_002881"
     CDS             <1..330
                     /locus_tag="ACF3UO_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3658790.1"
                     /translation="DLGGEKEKDIAVKLPGVTKNTNSKQSSDSKASFNHPSTFFNNNK
                     RSSNLNYNNSNKKRELMNQEKNKEGNRNKNTMELPKTGEKYNGLPVYVGLFTAIASII
                     GLKKNKF"
BASE COUNT          288 a          100 c          119 g          221 t
ORIGIN      
        1 gatcttggtg gagaaaaaga gaaagacata gcagtcaaat tacccggagt aacgaaaaat
       61 acaaattcta aacaaagttc ggatagtaaa gctagcttta atcatccttc tacttttttt
      121 aacaacaaca aaagatcatc taatctaaat tataataata gcaataaaaa aagggaacta
      181 atgaatcaag aaaaaaataa agaaggcaat cgaaataaaa atactatgga gttaccgaaa
      241 actggagaaa aatataatgg tcttcctgtg tatgtagggt tattcacggc gattgcaagt
      301 attatagggc tgaaaaaaaa taaattttaa tgtgggaatt attattattt ctctaattct
      361 atttgagcaa tttaaaatat gaaaatcaat aaagagaaag ttttaagttg ttaagtaaat
      421 taaatttcga ttggaagcat agttgaataa gcctaacatg ttacgaaaga taaataacct
      481 acttttcatt tctagaagag aatgtcttga tgcttataaa cagatttagc tccctatcca
      541 cttcaagtct aattcttttg tatgcaaata aagtattttt aggagagtgt tctcattaga
      601 gaacactctt tttttgtttt gaaaactact tactatacgg gtagtttcaa agtaagcgcc
      661 ccatagaaca gtaccttact aacaaatgca cctcaagata tacttgagct atcaagaagt
      721 ctggaggt
//
LOCUS       DAXLPQ010000177          696 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.189, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000177 DAXLPQ010000000
VERSION     DAXLPQ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.189"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(53..628)
                     /locus_tag="ACF3UO_002882"
     CDS             complement(53..628)
                     /locus_tag="ACF3UO_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFD3658791.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DAXLPQ010000178          669 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.190, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000178 DAXLPQ010000000
VERSION     DAXLPQ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.190"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>669
                     /locus_tag="ACF3UO_002883"
     CDS             <1..>669
                     /locus_tag="ACF3UO_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HFD3658792.1"
                     /translation="MYGYHYTPQTMSKMTKVLTEEVNAFKVRTLNDKYVAIFMDATYI
                     PLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRGVHDVLLF
                     ITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAVYQASSKE
                     EANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIESFNKQIK
                     KYSR"
BASE COUNT          228 a          124 c          126 g          191 t
ORIGIN      
        1 aaatgtatgg gtatcactac acgccccaaa ccatgtccaa aatgactaaa gtgctgactg
       61 aagaagtaaa tgcatttaaa gttagaactc taaatgataa gtatgtcgct attttcatgg
      121 atgctactta tattccttta aaacggcaaa ccgtctccaa agaagcaatc tatattgcca
      181 ttggtatacg agaagacggc actaaagaag tactaagtta tgcgattgct ccgactgaat
      241 cgacctacgt ttggaatgag ttgttacagg acatttactc cagaggggtt catgatgtct
      301 tactgtttat caccgatggc ttaaaaggca tgaaagatac gattcaccag atttatccta
      361 aagctaaata ccaacattgc tgtgttcacg tttcccgtaa tattgctcat aaagtacgtg
      421 tcaaagatcg aaaagaaatc tgtgatgatt ttaaggctgt ttatcaagct agctcaaagg
      481 aagaggcaaa taccttttta gggagtatga ttgagaagtg gcagaaaact tatcctaaag
      541 tgacgcagtc actgataaaa aatcaagatt tattgacttt ttatgagttt ccgcctggta
      601 tccgccgaag catttactca actaatttaa tcgaatcttt caataaacaa atcaagaaat
      661 acagccgca
//
LOCUS       DAXLPQ010000179          664 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.191, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000179 DAXLPQ010000000
VERSION     DAXLPQ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.191"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..242
                     /locus_tag="ACF3UO_002884"
     CDS             <1..242
                     /locus_tag="ACF3UO_002884"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3658793.1"
                     /translation="DPETPVTPETPDPETPVTPETSNYKTLQIQKSKVNYKSETNKTL
                     PKTGEAKSSGVFVGIIVLLTSIFAGFKLNLKRKKG"
BASE COUNT          279 a           84 c           98 g          203 t
ORIGIN      
        1 cagatccaga aactccggta acacctgaga ctccagatcc agaaaccccg gtaacgccag
       61 agactagtaa ttataaaact ctacaaatac aaaagagtaa ggtgaattat aaatctgaaa
      121 caaataaaac tcttccaaaa actggagagg caaaatcatc tggagtattt gtaggtataa
      181 tagttttatt gacttctatt tttgctggat ttaaattaaa tttgaaaaga aaaaaaggat
      241 agaaaataga tctgagatag aatacttagt gttctatctc aggttgtaat tatgttttat
      301 atcactcaag tattaaggag ggattatgat aactttagaa gagaaatata tataatcttt
      361 aggcaagaaa tgtataagaa aagagtctat ttaaatcata agtatattca agatactgaa
      421 tctcacgccc aatgtttaat atgcttggcc gaaaaaacgt attatattat tcattattca
      481 gaaatactta ttggttgatt ttttattttt tctagggaca aagacttgta attaaagaaa
      541 caggaaataa aaaacgaaaa attaagtctt ctttaacaaa aaaaacattg gaagataaga
      601 aattttcaat agaaaaatct catctctcaa aaaaaatatt atatacaatc gaaaaaaatt
      661 tttt
//
LOCUS       DAXLPQ010000180          651 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.192, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000180 DAXLPQ010000000
VERSION     DAXLPQ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.192"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            489..635
                     /locus_tag="ACF3UO_002885"
                     /pseudo
     CDS             489..635
                     /locus_tag="ACF3UO_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
BASE COUNT          215 a           91 c          100 g          245 t
ORIGIN      
        1 ttttagtctt gtcctttaat acaaagattt tatttttaaa taaaaaatac tcttttttta
       61 cgattattga aaaaaaaaga taaaacttga ttaattgaag tattgcttaa atttggaagc
      121 tatgagggaa gaataaaaga gttaggacgg gattatctac tatttttctt tgttttaaat
      181 atttgttatc tttgaacata aaagagaaat gtgtcgactg cagtgttgtg tccctcatca
      241 cgaataaacg gtgttcaatt agctgatctt gtattaactt aaaaaatggt aaagtacgag
      301 ttgctattcc ccattttcaa ttttctaacg ctcaggacaa aatactgttt tcacaacctc
      361 attggaataa aagcatatat attgtttcaa gaacgaaatc ttgttatctt tttaaagggc
      421 atctgtccaa aatctaattt taggaggtac gttttggtat ttattcgtac aaataaaaga
      481 gaattatctt tattcatgta acgcatccaa ttgatttttt catgtacgct cctggaacga
      541 ttttactgac gattgcttat ttaactgcga atcgctcatt agcttttatc atagctatcc
      601 atattttgaa taacgttctt ggctttgtat tatagataca gatgacaaaa a
//
LOCUS       DAXLPQ010000181          640 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.195, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000181 DAXLPQ010000000
VERSION     DAXLPQ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.195"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..283
                     /locus_tag="ACF3UO_002886"
     CDS             <1..283
                     /locus_tag="ACF3UO_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3658794.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          214 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt
//
LOCUS       DAXLPQ010000182          631 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.196, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000182 DAXLPQ010000000
VERSION     DAXLPQ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.196"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            28..>631
                     /locus_tag="ACF3UO_002887"
     CDS             28..>631
                     /locus_tag="ACF3UO_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658795.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDI"
BASE COUNT          216 a          114 c          123 g          178 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt g
//
LOCUS       DAXLPQ010000183          623 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.197, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000183 DAXLPQ010000000
VERSION     DAXLPQ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.197"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            16..>623
                     /locus_tag="ACF3UO_002888"
     CDS             16..>623
                     /locus_tag="ACF3UO_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HFD3658796.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRK"
BASE COUNT          201 a          110 c          127 g          185 t
ORIGIN      
        1 aggacgatat gctatatgaa tgattctatc aaaaaaatgc tgcgattaat agagaaagat
       61 ttgatgatta cagaggtctc ttacgagacc tttcagaaga aaaagacgtt gatcgtcgat
      121 gctgttttct cacctgctcc ccatacctgt agaaattgtg gttctactgt ggtagatgga
      181 aacgggaaag taattgtagt gaaaaatggg aagaaggaaa cgattgtccg ctttgaacaa
      241 tacaatcaca tgcctttggt tatgcgctta aaaaagcagc gctatacctg taaaaactgt
      301 cgaacccatt ggacggctca aagttatttt gttcaaccca gacattcaat cgcgaatcat
      361 gtcagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      421 aattgtcagg tatctttgac caccgttatt cgtacgttga aagagtttaa aagctactta
      481 ccaaagcaat ctaagaggat tctccccaga gtattgatgg ttgatgaatt tcgttcgcac
      541 gcttccatag aagataaaat gagctttatt tgcgcagatg gcgaaacagg acaattaatt
      601 gatgtcttgc ctacgcgtaa att
//
LOCUS       DAXLPQ010000184          608 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.198, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000184 DAXLPQ010000000
VERSION     DAXLPQ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.198"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(317..>608)
                     /locus_tag="ACF3UO_002889"
     CDS             complement(317..>608)
                     /locus_tag="ACF3UO_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658797.1"
                     /translation="REERIEQLPDCLEKEHLFQIREMLRNEQFDPNQFLVVEYSATGV
                     YCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSIEESISLTEC"
BASE COUNT          172 a          139 c           87 g          210 t
ORIGIN      
        1 cgcatcgacg aacgtcttcg tagtcagatt taacgttaaa atatcgccac tttgatacgc
       61 ttttgccgct ttgtctgtga cgacaaaagc tctgcccgtt tgaatttctg tcacaaaaac
      121 gagattgtct ctgctttttt caacaacaac tccaatcgtt gaataagcca tttcttcttc
      181 ctcccttctc tttcttttga tataatgtag tcgcaaatcg caccactcat tgaattggcg
      241 gaaaacaatt cattgaaaaa aagagtcctg gacaattacg ttcaggactc ttttacttct
      301 tttattcact taacaactaa cattctgtga gtgaaataga ctcttcaatg cttttacacg
      361 ggaagttatt gatcccctct tcattcattt cccaagtagt ataataaggc gctaacttgc
      421 cctcatattc ttgaatgata aaatattttt cacccttcac atgattacaa cagtacacac
      481 cagtagctga gtactcaacg actaaaaatt gatttggatc aaactgttcg tttctcaaca
      541 tttctcttat ctgaaacaaa tgctcttttt ctaaacaatc gggaagttgt tcgattcgtt
      601 cttctctt
//
LOCUS       DAXLPQ010000185          596 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.199, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000185 DAXLPQ010000000
VERSION     DAXLPQ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.199"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            76..>596
                     /locus_tag="ACF3UO_002890"
     CDS             76..>596
                     /locus_tag="ACF3UO_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFD3658798.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHH"
BASE COUNT          224 a          104 c          113 g          155 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg
      361 cgaaaagaaa ggcctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga
      421 atatttgata ttgacacact accgatgaaa ggtaaaagaa aacccaatgg ccatcaggaa
      481 aaacggggaa aacaacagta tcagcgctca atccatgatc gacctgataa ttatcctgat
      541 ttcaattctg agtttggtca ccttgaaggt gatacgatcg ttggcattca tcataa
//
LOCUS       DAXLPQ010000186          581 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.201, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000186 DAXLPQ010000000
VERSION     DAXLPQ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.201"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            16..>581
                     /locus_tag="ACF3UO_002891"
     CDS             16..>581
                     /locus_tag="ACF3UO_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFD3658799.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTT"
BASE COUNT          203 a          101 c          115 g          162 t
ORIGIN      
        1 gcaggaggaa tgacgatgaa tcattttaaa ggaaagcaat ttcagcagga tgtgattatt
       61 gtagccgtgg gctactatct tcgttataac cttagctatc gtgaagttca agaaatctta
      121 tatgatcgtg gcattaacgt ttctcatacg acgatttatc gttgggtgca agaatatggc
      181 aaactactct atcaaatttg gaaaaagaaa aataaaaaat ccttttattc atggaaaatg
      241 gatgaaacgt acatcaaaat taaaggaaaa tggcattatt tgtatcgagc catcgatgca
      301 gatggtttaa ccttggatat ttggttacgt aaaaaacggg acacacaagc agcctatgct
      361 tttcttaagc ggttagtgaa gcagtttgat gaaccgaagg ttgtagtcac agataaagcc
      421 ccctctatta caagtgcctt taagaaacta aaagaatacg gcttttatca agggacagaa
      481 catcgtacca ttaaatacct gaataatttg attgaacaag accatcgtcc agtaaagaga
      541 cgcaataaat tctatcgaag tttacgcact gcctctacca c
//
LOCUS       DAXLPQ010000187          572 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.202, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000187 DAXLPQ010000000
VERSION     DAXLPQ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.202"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>572
                     /locus_tag="ACF3UO_002892"
     CDS             <1..>572
                     /locus_tag="ACF3UO_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658800.1"
                     /translation="APYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLK
                     GNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNL
                     RQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYS
                     YSNGPLECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          191 a          119 c          109 g          153 t
ORIGIN      
        1 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
       61 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      121 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      181 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
      241 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
      301 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
      361 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
      421 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
      481 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
      541 cgtacggctt tcgcaacttt tacaatttca aa
//
LOCUS       DAXLPQ010000188          567 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.203, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000188 DAXLPQ010000000
VERSION     DAXLPQ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.203"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(170..>567)
                     /locus_tag="ACF3UO_002893"
     CDS             complement(170..>567)
                     /locus_tag="ACF3UO_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFD3658801.1"
                     /translation="FESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLP
                     AECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMK
                     YAKVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          168 a          105 c          108 g          186 t
ORIGIN      
        1 gggtcccgag cgcttagtgg gaatttgtac cccttatcga tacaaattcc tcgtaggcgc
       61 tagggacctc tttagcttct tggaagctgt cagtagtata tctaataatt tatctccatt
      121 ccctttagta acgtgtaact ttccaaattt aaaaaagcga ctcatagaat tatttcctcc
      181 cgttaaataa tagataacta ttaaaaatag acaatacttg ctcataagta acggtactta
      241 aatcgtttac tttggcgtat ttcattgctt gatgaaactg atttttagta aacagttgac
      301 gatattctcg attgacccat tttgaaacaa agtacgtata tagcttccaa tatttatctg
      361 gaacatctgt ggtatggcgg gtaagtttta ttaagacact gtttactttt ggtttaggat
      421 gaaagcattc cgctggcagc ttaagcaatt gctgaatcga gacttgagtg tgcaagagca
      481 accctagtgt tcggtgaata tccaaggtac gcttgtagaa tccttcttca acaatcagat
      541 agatgtcaga cgcatggctt tcaaaaa
//
LOCUS       DAXLPQ010000189          556 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.204, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000189 DAXLPQ010000000
VERSION     DAXLPQ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.204"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(152..346)
                     /locus_tag="ACF3UO_002894"
     CDS             complement(152..346)
                     /locus_tag="ACF3UO_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658802.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT          171 a          113 c           88 g          184 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caatgtgatg ttaggatgat
      541 ttcatggaca cgattt
//
LOCUS       DAXLPQ010000190          548 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.205, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000190 DAXLPQ010000000
VERSION     DAXLPQ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.205"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..399
                     /locus_tag="ACF3UO_002895"
     CDS             <1..399
                     /locus_tag="ACF3UO_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658803.1"
                     /translation="FDKLPKKVSSDVKDELKSIFKASELELTRERKEHFLEKYGCDSK
                     LSAACDILENGFEDAIQILSFPENIRRRIRTTNVLERLNEEIRRRERVIRIFPNINSI
                     TRIIGTLLMEKDTEWLASPRKYLEFNSNNI"
BASE COUNT          171 a           99 c          118 g          160 t
ORIGIN      
        1 tttgataagc tgccaaagaa agtttcttct gatgtaaaag acgagttgaa gagtatcttt
       61 aaagcctctg aacttgaatt gacacgtgaa agaaaagagc acttcttgga aaaatatggt
      121 tgtgattcaa aattaagtgc tgcttgcgac attttagaaa acggctttga agatgctatt
      181 caaattttgt cttttcctga aaatatccgc cgaaggattc gtacaaccaa tgtgttggaa
      241 cggttgaacg aagagattcg ccggagagaa cgagtgattc ggatttttcc aaatatcaat
      301 tccatcactc ggataattgg aacacttttg atggaaaaag acactgagtg gctggcttct
      361 ccacgaaaat atttagaatt taattcgaat aacatttagc accatgaacc tgtgcgagtc
      421 tcttctttct gaggagagac atcaagagtc gctgcgctac tgctcctgac ctctctcctc
      481 agaaagaaag gcatggcagt taggttcaca acgcaaaaca ttgtgctttt gatgaggttg
      541 aactttta
//
LOCUS       DAXLPQ010000191          534 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.206, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000191 DAXLPQ010000000
VERSION     DAXLPQ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.206"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>534
                     /locus_tag="ACF3UO_002896"
     CDS             <1..>534
                     /locus_tag="ACF3UO_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3658804.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDG"
BASE COUNT          208 a           71 c           96 g          159 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggc
//
LOCUS       DAXLPQ010000192          531 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.208, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000192 DAXLPQ010000000
VERSION     DAXLPQ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.208"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>531
                     /locus_tag="ACF3UO_002897"
     rRNA            <1..>531
                     /locus_tag="ACF3UO_002897"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          155 a          107 c          150 g          119 t
ORIGIN      
        1 gtatgtagtc gtagacccga aaccatgtga tctacccatg tccaggttga aggtgcggta
       61 aaacgcactg gaggaccgaa cccacgtacg ttgaaaagtg cggggatgag gtgtgggtag
      121 cggagaaatt ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta
      181 gcctcggaat tgagaatgat ggaggtagag cactgtttgg actaggggcc catctcgggt
      241 taccgaattc agataaactc cgaatgccat tcattcatat ccgggagtca gactgtgagt
      301 gataagatcc atagtcgaaa gggaaacagc ccagaccacc agctaaggtc ccaaaatata
      361 tgttaagtgg aaaaggatgt ggggttgcac agacaactag gatgttggct tagaagcagc
      421 caccatttaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
      481 ggggctaaac atattaccga agctgtggag tacaccttta ggtgtattgg t
//
LOCUS       DAXLPQ010000193          527 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.209, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000193 DAXLPQ010000000
VERSION     DAXLPQ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.209"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..84
                     /locus_tag="ACF3UO_002898"
     CDS             <1..84
                     /locus_tag="ACF3UO_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFD3658805.1"
                     /translation="YNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            108..347
                     /locus_tag="ACF3UO_002899"
     CDS             108..347
                     /locus_tag="ACF3UO_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658806.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSV
                     DTVRRVLKQDRDCCFIKVNTGRSRRLAKRYNSLIN"
BASE COUNT          183 a           59 c           92 g          193 t
ORIGIN      
        1 tataatgaaa tgcataattg gcctactttc tatccagctt cattatctga gcatgagatt
       61 gctcaagaaa tgatggccca ttaaaatcca atctttggag aaaatacatg gtaagaaaag
      121 tattattgtc tatggattcc aagaatattg atgcttatcg gcgttatcga tttgcaaagc
      181 aaatgagatt aaatgggagt acattagctg atattgctgc aactttacat gttagtgttg
      241 atacagttcg tagagtgtta aaacaagacc gggattgttg ttttatcaag gtcaatactg
      301 gaagaagtag acgtttagca aaacgatata atagtttgat taattagttg taacagtaga
      361 gcagattaat tttcttttat taggatttga tctgctcttt attatgtata ggaattaaca
      421 tattcgaaaa aatattacaa aattgtaatg ctattattta taattaatta ttttacaatg
      481 ctaaaattga tgataatatt ttattgtatc tgttaataaa agttttt
//
LOCUS       DAXLPQ010000194          507 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.211, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000194 DAXLPQ010000000
VERSION     DAXLPQ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.211"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..200)
                     /locus_tag="ACF3UO_002900"
     CDS             complement(<1..200)
                     /locus_tag="ACF3UO_002900"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3658807.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRP"
     gene            complement(311..>507)
                     /locus_tag="ACF3UO_002901"
     CDS             complement(311..>507)
                     /locus_tag="ACF3UO_002901"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658808.1"
                     /translation="SVRGLAKEYGLSEATIYKWKNLYLPDQSTGLTGKEVAELRKENA
                     RLNEELEILKKAAAIFSRKT"
BASE COUNT          151 a           91 c           73 g          192 t
ORIGIN      
        1 tgaggtctat attttttaac tacaatcgac cttaaattta attgtttcat tagcttttgg
       61 acatgtttaa gagatactga aatcccttct tttaataaaa cttgatggat ctttgtggca
      121 ccatagcgtt gtttattcgt aaaaaaaatt gttgaaatct tctttttcaa cttattattt
      181 ctgatttctg tagctgtcaa cggtttattc ttataaaaat aatagacact tctagggatt
      241 tctaataacc gacacaacaa agaaacagtg taatccttac accatttttc aataaattga
      301 acaagcgaat ttaggttttc cgagagaata tggctgcggc tttttttaag atttcaagtt
      361 cctcatttaa acgagcattt tcttttctca gttcagctac ttcttttcca gtcagtcctg
      421 tggactgatc aggtaaatat aaattcttcc atttgtaaat cgttgcttca gataagccat
      481 attctttcgc taaccctcga acagaac
//
LOCUS       DAXLPQ010000195          505 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.212, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000195 DAXLPQ010000000
VERSION     DAXLPQ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.212"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..475
                     /locus_tag="ACF3UO_002902"
     CDS             <1..475
                     /locus_tag="ACF3UO_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658809.1"
                     /translation="KKKQQAITPSENKQLEVHQVQEIKTSSNVERQSRGRTKKVGAPI
                     RKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELLRKALDEYIKQNLTQEDKQ
                     DLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDTEDSLRKGWGMNNKVR"
BASE COUNT          215 a           73 c           98 g          119 t
ORIGIN      
        1 aaagaaaaag cagcaagcaa ttacaccatc tgaaaataag caattagaag tgcaccaagt
       61 tcaagaaata aaaacttcct ccaatgttga aagacagagt agaggaagaa caaaaaaagt
      121 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
      181 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      241 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      301 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      361 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      421 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      481 aaagaagaac taagtaacta ccttt
//
LOCUS       DAXLPQ010000196          505 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.213, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000196 DAXLPQ010000000
VERSION     DAXLPQ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.213"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            16..>505
                     /locus_tag="ACF3UO_002903"
     CDS             16..>505
                     /locus_tag="ACF3UO_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFD3658810.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVY"
BASE COUNT          169 a           71 c          119 g          146 t
ORIGIN      
        1 aaaggaggca gatggatgaa aaaatggtta tttggttttt taggagtcac tttaatcgtc
       61 ttttgcagtg tgtttggcta tgttagctac caaaaacatg aaggagaggt gtttaagcaa
      121 aatatagaaa aaaagatgcc cgtagatcaa atcaatgcac atgcaaagag ttataaggag
      181 gatgcaacga acgtcaataa tgatatgtct ttggggcaaa tgttgtccat acaaaaagaa
      241 gcaatcgaaa tgggcgtcaa taaacaagta tttgcacaaa ttcagattcc tgcacttggt
      301 ttagcattgc caatttttaa aggggcaaat caatacactt tgagtcttgg agcggctact
      361 tatttttatg aagatgccga aatgggcaaa ggaaactatg tcctagcagg tcataacatg
      421 gaaatgccag gtgttttatt ttctgatatt caaaagttgt cattagggga ggtgatggac
      481 ttagttagta acgatggcgt ctatc
//
LOCUS       DAXLPQ010000197          503 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.214, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000197 DAXLPQ010000000
VERSION     DAXLPQ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.214"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            22..492
                     /locus_tag="ACF3UO_002904"
     CDS             22..492
                     /locus_tag="ACF3UO_002904"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFD3658811.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKITAAIESVL"
BASE COUNT          186 a           93 c           76 g          148 t
ORIGIN      
        1 aaatagaaag gagaaaactt tatgtctatt tataattttg aaactacttt agaagacggc
       61 actgtctatt cattgaaaaa atatgcaggc aaaccgataa tcattgttaa cactgcaaca
      121 aaatgcggtc tagcacctca atttaaacaa ttagaagaac tttaccaagc ttatcagaca
      181 caaggtctgg ttatcttagg ctttccttcc aatcaattta aacaagagct agattcagcg
      241 actgaagcag cagaagcttg taaaaccact tatggcgtta ccttccctat gcatcaattg
      301 attgacgtaa atggagaaaa tacagatcct ctttttactt atcttaaaaa tgaagctcct
      361 ggtactgtca ctaaagcaat aaaatggaat tttactaaat ttttgattga tagaaatggc
      421 aaagtaatcg aacgatttgc accacaaact tctccattga aaataaccgc tgcaattgaa
      481 tccgttcttt aacttaataa aaa
//
LOCUS       DAXLPQ010000198          499 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.215, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000198 DAXLPQ010000000
VERSION     DAXLPQ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.215"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>499
                     /locus_tag="ACF3UO_002905"
     rRNA            <1..>499
                     /locus_tag="ACF3UO_002905"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          162 a           99 c          141 g           97 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaa
//
LOCUS       DAXLPQ010000199          461 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.216, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000199 DAXLPQ010000000
VERSION     DAXLPQ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.216"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            4..243
                     /locus_tag="ACF3UO_002906"
     CDS             4..243
                     /locus_tag="ACF3UO_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658812.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT          193 a           60 c          102 g          106 t
ORIGIN      
        1 tagatggcgc gaccagtttt agaggcgatg gatatggata ctttgacaaa aggaaggtat
       61 gtacagctgt tagctcgtgg ttattcacct aaagaagtat tcaaagcctt atctaaagga
      121 acagatatgg aaaaagaaag attgcgaaaa gaattcgatt attggagaac ccataatgga
      181 atcaaggatt tgaaaccagc acggccagta attaaacgaa agaaaaagat aacccaagac
      241 tgaagtgtag agcgtatgtg atcataggct tttttatttt tgcaaaaaac aaggaaggta
      301 ggaaaactca tgaattatga agaaatcgaa aacagaaaaa aagtgtcgaa agaaatggaa
      361 gaaaagttac taaaaacgat gaagcaaaaa caccttaaaa gattatctgt cgcgcaatat
      421 atcaatgata tgcagttaac aggaaaagag aaagcttgtt t
//
LOCUS       DAXLPQ010000200          454 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.217, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000200 DAXLPQ010000000
VERSION     DAXLPQ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.217"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>454
                     /locus_tag="ACF3UO_002907"
     CDS             <1..>454
                     /locus_tag="ACF3UO_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD3658813.1"
                     /translation="CMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGIADPQPI
                     IQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRKQNLNLS
                     ALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSS"
BASE COUNT          170 a           77 c           67 g          140 t
ORIGIN      
        1 atgtatgtgt tgcagtcttc gcagtgattt attagcaata ttgatttctt tactggaaac
       61 aatagaagaa catcaacaac caatttcaca aatcatcatt gaaactacag gtatagcaga
      121 tccccaacca atcattcaaa cacttttaac agcgcctcaa ctaagaggaa gagtatatat
      181 cgatagttta ttgactgtta ttgatagtga cagttttgaa cttattgaaa gagaaccaca
      241 agcccttaag caacttgtca tggcagatcg catttttgtg tctagaaaac aaaacttgaa
      301 tttatctgca ctaaaaaaat tacagagaga aatcaaaagt attaaccctt tatccgatat
      361 tcgaatgttc acacatagtg aaacgattca aaaaaaggat ttttataatt tgaaaaaatt
      421 taatcatccc ttagtttttg aaagtgattc atca
//
LOCUS       DAXLPQ010000201          440 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.218, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000201 DAXLPQ010000000
VERSION     DAXLPQ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.218"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            11..>440
                     /locus_tag="ACF3UO_002908"
     CDS             11..>440
                     /locus_tag="ACF3UO_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3658814.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DAXLPQ010000202          436 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.219, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000202 DAXLPQ010000000
VERSION     DAXLPQ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.219"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            134..>436
                     /locus_tag="ACF3UO_002909"
     CDS             134..>436
                     /locus_tag="ACF3UO_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3658815.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMK"
BASE COUNT          168 a           54 c           72 g          142 t
ORIGIN      
        1 tttcaaatag ttttgtcatc ctaatcttca gcaacagaaa aaaatccaaa ttttaaaatt
       61 taggcttgac taaaatatat tttctgtata ccatataatc gtgataatca ttatcattta
      121 gaaggagaaa gttatgttag aagtgaaaaa gcttaatgtt tgttataacg attttttagc
      181 attgaacgag atttctttaa aaatacaaga aggtgctcta acaggtatta ttggtccaaa
      241 tggtgctgga aaatctacat tacttaaagc aatgttaaat attatccctc atcagggaga
      301 ggtctccatt aataatgaag atatcaataa aaaactggta aagattgcat atgtagagca
      361 aaaagctgat attgatttta cttttccaat aaaagtaaaa gaatgtgtat ctatgggaac
      421 gtatgccgga atgaaa
//
LOCUS       DAXLPQ010000203          435 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.220, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000203 DAXLPQ010000000
VERSION     DAXLPQ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.220"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..>435)
                     /locus_tag="ACF3UO_002910"
     CDS             complement(<1..>435)
                     /locus_tag="ACF3UO_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658816.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLS
                     YNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFK"
BASE COUNT          122 a           77 c           97 g          139 t
ORIGIN      
        1 tttaaacgac tgaggtaacg tagatgaaat tgttttaagg gtttcttgaa agccttccgt
       61 acctcgttta acgaaataat agcgtaataa ttgacaaaaa tgatacgcag ttcgcaattc
      121 ttcgttgtag cttaacagct catcaacgat ttctgtttga ctaattggtc gtttaaacag
      181 tcgatgataa tgccgtttga gtggctccca tgtcgtggaa tctttgagta agagtttcca
      241 atatcgcttg agccgacggt acttcttctg attttcagag tgtgaggttc gaaaacgatt
      301 catgatctgg acacgtaatt gattgaagct gcgattgatg tgttggacaa tatgaaagcg
      361 gtcagttacg atctccgcat ttggaaagac tgttttaagc aactgacaat agctggcatt
      421 catgtccatc actag
//
LOCUS       DAXLPQ010000204          419 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.221, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000204 DAXLPQ010000000
VERSION     DAXLPQ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.221"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            15..>419
                     /locus_tag="ACF3UO_002911"
     CDS             15..>419
                     /locus_tag="ACF3UO_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFD3658817.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMS"
BASE COUNT          153 a           78 c           69 g          119 t
ORIGIN      
        1 aagaggactt ccctatgaat gattttacta cagaaattgt gcaaactcta gtcactaaag
       61 gcgatttaaa tgaattattc cgttcgcact tagaaaaagc gataaacaca ctcctacgga
      121 ctgaattaac ggctttttta gattacgaaa aatatgatcg cactggtttt aattcaggta
      181 attcgagaaa cggttcttac tttcgatcaa tcaaaaccga atatggtgaa ttaacattgg
      241 aaatacctag agatcgtaat ggtgagttta aacaacaaac tttaccagcc tacaaaagaa
      301 caaacgatac attggaaacc actattatcc atttattcga aaaaggtgtt acgatgtctg
      361 aaattgctga tttgatcgaa aaaatgtacg gtcatcacta tactccacaa accatgtcc
//
LOCUS       DAXLPQ010000205          415 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.222, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000205 DAXLPQ010000000
VERSION     DAXLPQ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.222"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..339)
                     /locus_tag="ACF3UO_002912"
     CDS             complement(<1..339)
                     /locus_tag="ACF3UO_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658818.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAXLPQ010000206          403 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.223, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000206 DAXLPQ010000000
VERSION     DAXLPQ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.223"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..382
                     /locus_tag="ACF3UO_002913"
     CDS             <1..382
                     /locus_tag="ACF3UO_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658819.1"
                     /translation="KRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWL
                     KTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNR
                     NRIHSSIHYLTPQEFEELAKEKMA"
BASE COUNT          159 a           76 c           70 g           98 t
ORIGIN      
        1 aaaacgaatg actgtggatt gtgtcattca aacattgaat aaagcaaaaa tacattatca
       61 cattccagaa ggaatgattc tacacactga cttgggcagc caatacacag caagagaagt
      121 ggaacaatgg cttaaaacca acaaaataag gcattcttat agtagaaaag gaacacctta
      181 tgataatgct ggaatcgaat ctttccatgc ctcattgaaa aaagaagaag tctacacgac
      241 tagctactca gattttgaag aagcaaatcg agcgctattt agctacattg aaggatttta
      301 taaccgaaat cgaatccata gctcgattca ctatctaacc ccacaggaat ttgaagaatt
      361 agcaaaagaa aaaatggctt aaccgtctct actaaaatgt gtc
//
LOCUS       DAXLPQ010000207          398 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.224, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000207 DAXLPQ010000000
VERSION     DAXLPQ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.224"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            105..380
                     /locus_tag="ACF3UO_002914"
     CDS             105..380
                     /locus_tag="ACF3UO_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658820.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT          170 a           60 c           54 g          114 t
ORIGIN      
        1 aataaccact atttgattta tatatatttc agtatccttc ttgttttcat ataaccaaag
       61 gcgctatgat ttccatatga aaaaaataaa gtcaggtgaa aaaaatgaaa cttgaggata
      121 aaaaagtcat tttgaagaaa atcaaacgac taccagacca aatagatggc tatacgatct
      181 gttctttcaa aaaagacagg agtataaaag cttatacgca aaacacagaa aaaggaataa
      241 tctatttcct acatgaagaa ggttacgata cccaaacctt tatgtttact gaaaaaaaag
      301 aatttcataa acagatgaaa aaactgattg aaaaagaatt tccaagaagt cataaactct
      361 atgtgaatca gcaattttaa cttctaactg ttctttat
//
LOCUS       DAXLPQ010000208          385 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.225, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000208 DAXLPQ010000000
VERSION     DAXLPQ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.225"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..372
                     /locus_tag="ACF3UO_002915"
     CDS             <1..372
                     /locus_tag="ACF3UO_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658821.1"
                     /translation="CDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDL
                     LTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKF
                     LNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          145 a           70 c           58 g          112 t
ORIGIN      
        1 tgtgatgact ttaaggctgt ttatcaagct aactcaaaag aagaagcgaa taccttctta
       61 tccggcatga ttgagaaatg gaagaaaaac tatcctaaag tgacgcagtc actcatagaa
      121 aaccaagact tattaacttt ttatgatttt ccacctagca ttcgtagaac catttactca
      181 accaatctaa tcgagtcttt caataagcaa attaaaagat acagccgtag aaaagagcag
      241 tttcaaaatg aagaatcact agaacgcttt ctagtcagca tttttgatac atacaatcaa
      301 aaatttctaa acagaagcca taaaggtttt caacaggtaa ccgatacatt agtttcaatg
      361 tttactgagt aactaattat tttgc
//
LOCUS       DAXLPQ010000209          381 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.226, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000209 DAXLPQ010000000
VERSION     DAXLPQ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.226"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..>381)
                     /locus_tag="ACF3UO_002916"
     rRNA            complement(<1..>381)
                     /locus_tag="ACF3UO_002916"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           85 a          110 c           94 g           92 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc a
//
LOCUS       DAXLPQ010000210          362 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.228, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000210 DAXLPQ010000000
VERSION     DAXLPQ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.228"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..>362)
                     /locus_tag="ACF3UO_002917"
     rRNA            complement(<1..>362)
                     /locus_tag="ACF3UO_002917"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           81 a          114 c           68 g           99 t
ORIGIN      
        1 tctcactaga agcttttctc ggcagtgtga catcaggaac ttcggtacta ttatttccct
       61 ccccatcaca gcttgtcctt aagaaaagaa gcatttgact cctcttcaga cttactgctt
      121 ggacagacat ttccgatcgt ctgcattcct tagcctcctg cgtccctcca ttgctcaaac
      181 aaaaacaacg ggtacaggaa tatcaacctg ttatccatcg cctacgcctg tcggcctcgg
      241 cttaggtccc gactaaccct gggcggacga gccttcccca ggaaacctta gtcattcggt
      301 ggacaggatt ctcacctgtc tttcgctact cataccggca ttctcacttc taagcgctcc
      361 ag
//
LOCUS       DAXLPQ010000211          349 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.229, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000211 DAXLPQ010000000
VERSION     DAXLPQ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.229"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(44..>349)
                     /locus_tag="ACF3UO_002918"
     CDS             complement(44..>349)
                     /locus_tag="ACF3UO_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3658822.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           98 a           86 c           64 g          101 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggt
//
LOCUS       DAXLPQ010000212          339 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.230, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000212 DAXLPQ010000000
VERSION     DAXLPQ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.230"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            42..164
                     /locus_tag="ACF3UO_002919"
     CDS             42..164
                     /locus_tag="ACF3UO_002919"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658823.1"
                     /translation="MHKPFPDPIQKAIDELGIKNKKRFILVIHYMTCKVRKLVG"
     gene            137..268
                     /locus_tag="ACF3UO_002920"
     CDS             137..268
                     /locus_tag="ACF3UO_002920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658824.1"
                     /translation="MQSAKACGIAFGLAKWGAKNIENFQSVDIIIDSPQEILDLLEK"
BASE COUNT          122 a           45 c           64 g          108 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgc
//
LOCUS       DAXLPQ010000213          323 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.231, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000213 DAXLPQ010000000
VERSION     DAXLPQ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.231"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..>323)
                     /locus_tag="ACF3UO_002921"
     rRNA            complement(<1..>323)
                     /locus_tag="ACF3UO_002921"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           64 a           96 c           74 g           89 t
ORIGIN      
        1 ataaatccgg acaacgcttg ccacctacgt attaccgcgg ctgctggcac gtagttagcc
       61 gtggctttct ggttagatac cgtcaaggga tgaacagtta ctctcatcct tgttcttctc
      121 taacaacaga gttttacgat ccgaaaacct tcttcactca cgcggcgttg ctcggtcaga
      181 ctttcgtcca ttgccgaaga ttccctactg ctgcctcccg taggagtttg ggccgtgtct
      241 cagtcccaat gtggccgatc accctctcag gtcggctatg catcgtggcc ttggtgagcc
      301 gttacctcac caactagcta atg
//
LOCUS       DAXLPQ010000214          311 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.232, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000214 DAXLPQ010000000
VERSION     DAXLPQ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.232"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..134
                     /locus_tag="ACF3UO_002922"
     CDS             <1..134
                     /locus_tag="ACF3UO_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658825.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT          135 a           49 c           30 g           97 t
ORIGIN      
        1 aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc atacaaacaa aaataaataa agtcggattt ttctgataat
      181 tcaacgcaaa aaaacgaaca atttttcaat aaatcagtct tctaaaatag ataacctaaa
      241 aaaaacgaac aaacaaataa aatgactgtc cttcattcac taaacatatt tttatttttt
      301 atattgttaa a
//
LOCUS       DAXLPQ010000215          305 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.233, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000215 DAXLPQ010000000
VERSION     DAXLPQ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.233"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACF3UO_002923"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACF3UO_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFD3658826.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DAXLPQ010000216          304 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.234, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000216 DAXLPQ010000000
VERSION     DAXLPQ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.234"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..>304)
                     /locus_tag="ACF3UO_002924"
     CDS             complement(<1..>304)
                     /locus_tag="ACF3UO_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658827.1"
                     /translation="PLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGLPTQQAI
                     ENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLVSQLES"
BASE COUNT           97 a           64 c           40 g          103 t
ORIGIN      
        1 agattccaat tgtgaaacta aattttcttt catatcaaca ggtatctccc aataaccatc
       61 gatacattga aataactcct cgtcatactc ttcaaaaatt ggatagattc ttaaaaaatc
      121 atcaaatgat aagccttggt cctcatagta atctttgact aatccatttt caattgcctg
      181 ttgggtcggt aaacccgttt cagtaataat tcctctctct accatcgaac gataaaaagt
      241 gcatttatct agcgattgct gggtcgtttc aagataatac tttaatcctt cttcaactaa
      301 aggt
//
LOCUS       DAXLPQ010000217          284 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.235, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000217 DAXLPQ010000000
VERSION     DAXLPQ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.235"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..>284)
                     /locus_tag="ACF3UO_002925"
     CDS             complement(<1..>284)
                     /locus_tag="ACF3UO_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658828.1"
                     /translation="ESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQR
                     GLNENSNGLLRRDGLLKSMDFNSVDEFFIQSVASKRNNIPRKSLDYRTPL"
BASE COUNT           91 a           50 c           48 g           95 t
ORIGIN      
        1 ccaaaggtgt tcgataatcc agtgattttc taggaatatt atttcgttta gatgcgacag
       61 attgaataaa aaattcatct actgaattga aatccataga tttcaataaa ccatctctac
      121 gtaacaatcc gttagaattc tcgtttaggc ctctttgaga cggcgttcct ggatcagcga
      181 aataaatggc aatatcattg acattactga tctgtttcca atttgaaaat tcctttccac
      241 aatcaaaagt gatggatttg aataggtttt tcggtacaga ttca
//
LOCUS       DAXLPQ010000218          274 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.236, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000218 DAXLPQ010000000
VERSION     DAXLPQ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.236"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>274
                     /locus_tag="ACF3UO_002926"
     CDS             <1..>274
                     /locus_tag="ACF3UO_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFD3658829.1"
                     /translation="EYKDYYTTGYKTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKI
                     LNYEKGNRGVRFNFETDDAGAGRFKYIQFSDHGIAPSKAEHFHIFFG"
BASE COUNT           96 a           40 c           49 g           89 t
ORIGIN      
        1 ccgagtacaa agattattat actactggct ataagacaga tattgatact atcaacatta
       61 aagacaacac cattgatttt gtagtcaacg gtgaacatca tcaatacaca tacaaatatg
      121 ttggatacaa aattttgaat tatgaaaaag gaaaccgtgg tgttcgtttt aattttgaaa
      181 ctgatgatgc aggtgctggt cgttttaaat atattcaatt tagtgatcat ggaattgcac
      241 caagtaaggc agagcatttc catattttct ttgg
//
LOCUS       DAXLPQ010000219          271 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.237, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000219 DAXLPQ010000000
VERSION     DAXLPQ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.237"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>271
                     /locus_tag="ACF3UO_002927"
     CDS             <1..>271
                     /locus_tag="ACF3UO_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658830.1"
                     /translation="KEKLTILELKRTRFLCHDCGRTFSAKTDLVDEHHQLTKELKQAI
                     LMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL"
BASE COUNT           87 a           57 c           59 g           68 t
ORIGIN      
        1 caaagaaaag ttaactattt tagaattaaa acgtacccgt tttctctgcc atgattgtgg
       61 aaggaccttt tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact
      121 gaagcaggcg attctcatgg aactgtacga aaatcaatca cgtaaactaa tcgctaagaa
      181 gtacttcgtc tcggatggga cggtgacacg gatcttgcgt gaagcaacga agcattacca
      241 gccacgtatg aacttccttc cgacggtgtt g
//
LOCUS       DAXLPQ010000220          261 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.238, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000220 DAXLPQ010000000
VERSION     DAXLPQ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.238"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>261
                     /locus_tag="ACF3UO_002928"
     CDS             <1..>261
                     /locus_tag="ACF3UO_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658831.1"
                     /translation="FPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTK
                     TGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT           95 a           47 c           43 g           76 t
ORIGIN      
        1 gttttcctag tccattatgt aaaccagtta gaaatagaca agcaaaacta ttgaatcaaa
       61 tagccaaagt tggctataac tcaacaaaaa aatcttattt ttatggtctt aaaattcata
      121 tgatcgttac taagactggc tttccgatta cttactcaat cacgaatcca ggtgtccatg
      181 acgtgaaagt gttagagact ttatcggaag aagcgaatct tcccaatatc ctaggggaca
      241 aaggatatat tagccataaa a
//
LOCUS       DAXLPQ010000221          259 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.239, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000221 DAXLPQ010000000
VERSION     DAXLPQ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.239"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
BASE COUNT          104 a           42 c           27 g           86 t
ORIGIN      
        1 ctctactaca ccatatctat tgacaatcaa ccaaataaaa tacagtattt cacgatatag
       61 tgtgataaat aacaaaatag aagcaataaa gcttcttgtg ttaaaacaat tataaaagaa
      121 ctaaataatt agcccttcta tctataaaaa agtcaatagc gtcactagga tttcctaata
      181 acgctattga ttttcttttc ctctgaaatt aaatcagaaa gatttttcaa taatgataac
      241 tgttttgatt aacagcttt
//
LOCUS       DAXLPQ010000222          257 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.240, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000222 DAXLPQ010000000
VERSION     DAXLPQ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.240"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            163..>257
                     /gene="rrf"
                     /locus_tag="ACF3UO_002929"
     rRNA            163..>257
                     /gene="rrf"
                     /locus_tag="ACF3UO_002929"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT           89 a           44 c           64 g           60 t
ORIGIN      
        1 taggtcagga gtggaagtac agtgatgtat ggagcggact gatactaatc gatcgaggac
       61 ttaaccaata ggttaaaaga aaagaactcg gaaaaaaact tatgtgactt caaatccagt
      121 tttgagtgaa caaaatttac tcaataaaag ataacaccac agtgtggtgg cgatagcgag
      181 aaggatacac ctgtaaccat gccgaacaca gaagttaagc ttcttagcgc cgattgtagt
      241 gaggggttgc cccttgt
//
LOCUS       DAXLPQ010000223          255 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.241, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000223 DAXLPQ010000000
VERSION     DAXLPQ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.241"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..>255)
                     /locus_tag="ACF3UO_002930"
     CDS             complement(<1..>255)
                     /locus_tag="ACF3UO_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3658832.1"
                     /translation="AEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELL
                     KKANTIIVATDSDREGENIAWSIIHKANAFSKDKTFKRLW"
BASE COUNT           67 a           51 c           38 g           99 t
ORIGIN      
        1 atccatagtc ttttaaatgt tttatctttt gaaaaggcat ttgctttatg gataatcgac
       61 caggcgatat tttcaccttc tctgtcgcta tctgttgcaa caataattgt atttgccttt
      121 ttgagaagtt ctgcaacaat tttaaactgc tttcccttat cttttgcaac ttcaaaatcg
      181 tatcgatcag gaaaaatcgg caaagattca agtttccaat tttgccactt ttcgtcataa
      241 tgacctggtt ctgct
//
LOCUS       DAXLPQ010000224          241 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.242, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000224 DAXLPQ010000000
VERSION     DAXLPQ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.242"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..220)
                     /locus_tag="ACF3UO_002931"
     CDS             complement(<1..220)
                     /locus_tag="ACF3UO_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658833.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAXLPQ010000225          232 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.243, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000225 DAXLPQ010000000
VERSION     DAXLPQ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.243"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
BASE COUNT           79 a           35 c           45 g           73 t
ORIGIN      
        1 gagaaaaagc atggaatgcg ctgcatcagg tatcgaggct tagaaaaaaa tcaggtgcat
       61 acgatgcttg tttttgccga aatgagtctg aaaaaattgg tcacttagca gtgggagcat
      121 atgtcttcat attttttatt atacaaaaat agacaaaagt atcagtctac actcttagta
      181 aagaggaaac tgatactttt gtctacagta tgatatttct tacatctact tt
//
LOCUS       DAXLPQ010000226          229 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.245, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000226 DAXLPQ010000000
VERSION     DAXLPQ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.245"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..185
                     /locus_tag="ACF3UO_002932"
     CDS             <1..185
                     /locus_tag="ACF3UO_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3658834.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           61 a           51 c           57 g           60 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggagg
//
LOCUS       DAXLPQ010000227          225 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.246, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000227 DAXLPQ010000000
VERSION     DAXLPQ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.246"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..175)
                     /locus_tag="ACF3UO_002933"
     rRNA            complement(<1..175)
                     /locus_tag="ACF3UO_002933"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           50 a           60 c           49 g           66 t
ORIGIN      
        1 cctgtttcca agtgttatcc ccttctgatg ggcaggttac ccacgtgtta ctcacccgtt
       61 cgccactcct ctttttccgg tggagcaagc tccggtggaa aaagaagcgt tcgacttgca
      121 tgtattaggc acgccgccag cgttcgtcct gagccaggat caaactctca taaaaagttc
      181 gaacaatctt gcgattgtta agctcaattt gtttgctagc atatt
//
LOCUS       DAXLPQ010000228          222 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.247, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000228 DAXLPQ010000000
VERSION     DAXLPQ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.247"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..>222
                     /locus_tag="ACF3UO_002934"
     CDS             <1..>222
                     /locus_tag="ACF3UO_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3658835.1"
                     /translation="GRKALDIETALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQH
                     DIDIYFADPGTPSQRPLNENSNGILRRNGL"
BASE COUNT           67 a           46 c           40 g           69 t
ORIGIN      
        1 ggccgtaagg cattagatat tgaaactgcc cttaatcaat ggttttctcg cttccctaaa
       61 aacttcttta aatctattac gtttgactgt ggaaaagaat tttctaactg gaaagccatt
      121 agtaaccaac atgatattga tatatatttt gcggaccctg gaacaccttc tcaacgccca
      181 ttaaacgaga attctaacgg gattctgcgt cgtaatggac tg
//
LOCUS       DAXLPQ010000229          220 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.denovo.248, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000229 DAXLPQ010000000
VERSION     DAXLPQ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.denovo.248"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..149
                     /locus_tag="ACF3UO_002935"
     CDS             <1..149
                     /locus_tag="ACF3UO_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3658836.1"
                     /translation="AFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGL
                     IFEN"
BASE COUNT           68 a           48 c           44 g           60 t
ORIGIN      
        1 atgcctttaa ggtgtcccac tcaaacggcg tcactgaggg gctgaataac aagatcaagc
       61 tgattaaacg aattgcgttt ggttatcgca acttttataa ctttcgggca cggatctatt
      121 tacaacaagg tctgatcttt gaaaactaaa aaaatatgcg gcgcacagaa cgcgccgcat
      181 atcggactaa gttttattca aatttgtctt caccaacacg
//
LOCUS       DAXLPQ010000230        13246 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.062, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000230 DAXLPQ010000000
VERSION     DAXLPQ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.062"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(204..2162)
                     /gene="nagE"
                     /locus_tag="ACF3UO_002936"
     CDS             complement(204..2162)
                     /gene="nagE"
                     /locus_tag="ACF3UO_002936"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFD3658837.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="ACF3UO_002937"
     CDS             complement(2159..3031)
                     /locus_tag="ACF3UO_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFD3658838.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="ACF3UO_002938"
     CDS             complement(3373..4245)
                     /locus_tag="ACF3UO_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3658839.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="ACF3UO_002939"
     CDS             4373..4942
                     /locus_tag="ACF3UO_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFD3658840.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="ACF3UO_002940"
     CDS             5009..5746
                     /locus_tag="ACF3UO_002940"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3658841.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="ACF3UO_002941"
     CDS             5977..7245
                     /locus_tag="ACF3UO_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3658842.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="ACF3UO_002942"
     CDS             7732..8196
                     /locus_tag="ACF3UO_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3658843.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="ACF3UO_002943"
     CDS             8180..8809
                     /locus_tag="ACF3UO_002943"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3658844.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="ACF3UO_002944"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="ACF3UO_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFD3658845.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="ACF3UO_002945"
     CDS             10688..11134
                     /locus_tag="ACF3UO_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFD3658846.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="ACF3UO_002946"
     CDS             complement(11333..11848)
                     /locus_tag="ACF3UO_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3658847.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="ACF3UO_002947"
     CDS             11965..13167
                     /locus_tag="ACF3UO_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3658848.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4129 a         2431 c         2711 g         3975 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatag aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaacagccaa acaaaaatag cttctcatat ttttcg
//
LOCUS       DAXLPQ010000231        12320 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.065, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000231 DAXLPQ010000000
VERSION     DAXLPQ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.065"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            104..799
                     /gene="vanR-A"
                     /locus_tag="ACF3UO_002948"
     CDS             104..799
                     /gene="vanR-A"
                     /locus_tag="ACF3UO_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFD3658849.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            777..1931
                     /locus_tag="ACF3UO_002949"
     CDS             777..1931
                     /locus_tag="ACF3UO_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFD3658850.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2146..3114
                     /locus_tag="ACF3UO_002950"
     CDS             2146..3114
                     /locus_tag="ACF3UO_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFD3658851.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3107..4138
                     /gene="vanA"
                     /locus_tag="ACF3UO_002951"
     CDS             3107..4138
                     /gene="vanA"
                     /locus_tag="ACF3UO_002951"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFD3658852.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4144..4752
                     /locus_tag="ACF3UO_002952"
     CDS             4144..4752
                     /locus_tag="ACF3UO_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFD3658853.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            5202..6092
                     /locus_tag="ACF3UO_002953"
     CDS             5202..6092
                     /locus_tag="ACF3UO_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFD3658854.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            6245..6730
                     /gene="vanZ-A"
                     /locus_tag="ACF3UO_002954"
     CDS             6245..6730
                     /gene="vanZ-A"
                     /locus_tag="ACF3UO_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFD3658855.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            7000..7230
                     /locus_tag="ACF3UO_002955"
     CDS             7000..7230
                     /locus_tag="ACF3UO_002955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658856.1"
                     /translation="MNKVHVYNHNKFVKEINSDTNSIAKEIASQSPFAELKMTDEYDN
                     LILTTKGFFLDDVPNQIWLKNELMPALTNLQI"
     gene            complement(7277..7540)
                     /locus_tag="ACF3UO_002956"
                     /pseudo
     CDS             complement(7277..7540)
                     /locus_tag="ACF3UO_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043131.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(7565..8887)
                     /locus_tag="ACF3UO_002957"
     CDS             complement(7565..8887)
                     /locus_tag="ACF3UO_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3658857.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGRLCYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTLIKNLEKGDL"
     gene            complement(9129..10769)
                     /gene="merA"
                     /locus_tag="ACF3UO_002958"
     CDS             complement(9129..10769)
                     /gene="merA"
                     /locus_tag="ACF3UO_002958"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFD3658858.1"
                     /translation="MNKFKVNIQGMTCTGCEKHVESALEKIGAKNIESNFRRGEAVFE
                     LPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALINEDDYDLLIIGSGAAAFSSAIK
                     AIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFKGLQTSAGEVDL
                     ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGAKLSAKRFLIA
                     TGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEIT
                     LMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKKVYITVNGSKE
                     VIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGP
                     QFVYVAAYEGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVK
                     TSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDVIYAASLAVKFGL
                     TIEDLTETLAPYLTMAEGLKLAALTFDKDVSKLSCCAG"
     gene            complement(10794..11186)
                     /gene="merR"
                     /locus_tag="ACF3UO_002959"
     CDS             complement(10794..11186)
                     /gene="merR"
                     /locus_tag="ACF3UO_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFD3658859.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELSFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            11456..11689
                     /locus_tag="ACF3UO_002960"
     CDS             11456..11689
                     /locus_tag="ACF3UO_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658860.1"
                     /translation="MRGINNHQKYDFDLYQIEARSPMSTREITLTVDFIEKKVSGDII
                     AFGDWYDLDIESVNEILKQLKKEGQTLRTINFI"
     gene            complement(11712..11969)
                     /locus_tag="ACF3UO_002961"
     CDS             complement(11712..11969)
                     /locus_tag="ACF3UO_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658861.1"
                     /translation="MANNDLNDINKRIEKLKIQKNILRANSEQNINRKRRTKRLIEKG
                     ALLEKYFEIDYLTVEETEEFLKIFSEYIKANKPKKYQKKEK"
     gene            complement(11972..12271)
                     /locus_tag="ACF3UO_002962"
     CDS             complement(11972..12271)
                     /locus_tag="ACF3UO_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658862.1"
                     /translation="MENQDQNINAINGNFNSKTKPKKRKKKTVSDIELQIKELQKKKE
                     ELILKSKADIGDFVLSTLSKLDISIESIEENKELFYDELETLLNANSQNFSELLK"
BASE COUNT         3863 a         2238 c         2339 g         3880 t
ORIGIN      
        1 taaaatttgg tagtttataa aaagtatgaa ttattcaggt ataaattcgg ccctataatc
       61 tgataaatta ttaagggcaa acttatgtga aagggtgata actatgagcg ataaaatact
      121 tattgtggat gatgaacatg aaattgccga tttggttgaa ttatacttaa aaaacgagaa
      181 ttatacggtt ttcaaatact ataccgccaa agaagcattg gaatgtatag acaagtctga
      241 gattgacctt gccatattgg acatcatgct tcccggcaca agcggcctta ctatctgtca
      301 aaaaataagg gacaagcaca cctatccgat tatcatgctg accgggaaag atacagaggt
      361 agataaaatt acagggttaa caatcggcgc ggatgattat ataacgaagc cctttcgccc
      421 actggagtta attgctcggg taaaggccca gttgcgccga tacaaaaaat tcagtggagt
      481 aaaggagcag aacgaaaatg ttatcgtcca ctccggcctt gtcattaatg ttaacaccca
      541 tgagtgttat ctgaacgaga agcagttatc ccttactccc accgagtttt caatactgcg
      601 aatcctctgt gaaaacaagg ggaatgtggt tagctccgag ctgctatttc atgagatatg
      661 gggcgacgaa tatttcagca agagcaacaa caccatcacc gtgcatatcc ggcatttgcg
      721 cgaaaaaatg aacgacacca ttgataatcc gaaatatata aaaacggtat ggggggttgg
      781 ttataaaatt gaaaaataaa aaaaacgact attccaaact agaacgaaaa ctttacatgt
      841 atatcgttgc aattgttgtg gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc
      901 gagggaaact tggggattgg atcttaagta ttttggaaaa caaatatgac ttaaatcacc
      961 tggacgcgat gaaattatat caatattcca tacggaacaa tatagatatc tttatttatg
     1021 tggcgattgt cattagtatt cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat
     1081 actttgacga gataaatacc ggcattgatg tacttattca gaacgaagat aaacaaattg
     1141 agctttctgc ggaaatggat gttatggaac aaaagctcaa cacattaaaa cggactctgg
     1201 aaaagcgaga gcaggatgca aagctggccg aacaaagaaa aaatgacgtt gttatgtact
     1261 tggcgcacga tattaaaacg ccccttacat ccattatcgg ttatttgagc ctgcttgacg
     1321 aggctccaga catgccggta gatcaaaagg caaagtatgt gcatatcacg ttggacaaag
     1381 cgtatcgact cgaacagcta atcgacgagt tttttgagat tacacggtat aacctacaaa
     1441 cgataacgct aacaaaaacg cacatagacc tatactatat gctggtgcag atgaccgatg
     1501 aattttatcc tcagctttcc gcacatggaa aacaggcggt tattcacgcc cccgaggatc
     1561 tgaccgtgtc cggcgaccct gataaactcg cgagagtctt taacaacatt ttgaaaaacg
     1621 ccgctgcata cagtgaggat aacagcatca ttgacattac cgcgggcctc tccggggatg
     1681 tggtgtcaat cgaattcaag aacactggaa gcatcccaaa agataagcta gctgccatat
     1741 ttgaaaagtt ctataggctg gacaatgctc gttcttccga tacgggtggc gcgggacttg
     1801 gattggcgat tgcaaaagaa attattgttc agcatggagg gcagatttac gcggaaagca
     1861 atgataacta tacgacgttt agggtagagc ttccagcgat gccagacttg gttgataaaa
     1921 ggaggtccta agagatgtat ataatttttt aggaaaatct caaggttatc tttacttttt
     1981 cttaggaaat taacaattta atattaagaa acggctcgtt cttacacggt agacttaata
     2041 ccgtaagaac gagccgtttt cgttcttcag agaaagattt gacaagatta ccattggcat
     2101 ccccgtttta tttggtgcct ttcacagaaa gggttggtct taattatgaa taacatcggc
     2161 attactgttt atggatgtga gcaggatgag gcagatgcat tccatgctct ttcgcctcgc
     2221 tttggcgtta tggcaacgat aattaacgcc aacgtgtcgg aatccaacgc caaatccgcg
     2281 cctttcaatc aatgtatcag tgtgggacat aaatcagaga tttccgcctc tattcttctt
     2341 gcgctgaaga gagccggtgt gaaatatatt tctacccgaa gcatcggctg caatcatata
     2401 gatacaactg ctgctaagag aatgggcatc actgtcgaca atgtggcgta ctcgccggat
     2461 agcgttgccg attatactat gatgctaatt cttatggcag tacgcaacgt aaaatcgatt
     2521 gtgcgctctg tggaaaaaca tgatttcagg ttggacagcg accgtggcaa ggtactcagc
     2581 gacatgacag ttggtgtggt gggaacgggc cagataggca aagcggttat tgagcggctg
     2641 cgaggatttg gatgtaaagt gttggcttat agtcgcagcc gaagtataga ggtaaactat
     2701 gtaccgtttg atgagttgct gcaaaatagc gatatcgtta cgcttcatgt gccgctcaat
     2761 acggatacgc actatattat cagccacgaa caaatacaga gaatgaagca aggagcattt
     2821 cttatcaata ctgggcgcgg tccacttgta gatacctatg agttggttaa agcattagaa
     2881 aacgggaaac tgggcggtgc cgcattggat gtattggaag gagaggaaga gtttttctac
     2941 tctgattgca cccaaaaacc aattgataat caatttttac ttaaacttca aagaatgcct
     3001 aacgtgataa tcacaccgca tacggcctat tataccgagc aagcgttgcg tgataccgtt
     3061 gaaaaaacca ttaaaaactg tttggatttt gaaaggagac aggagcatga atagaataaa
     3121 agttgcaata ctgtttgggg gttgctcaga ggagcatgac gtatcggtaa aatctgcaat
     3181 agagatagcc gctaacatta ataaagaaaa atacgagccg ttatacattg gaattacgaa
     3241 atctggtgta tggaaaatgt gcgaaaaacc ttgcgcggaa tgggaaaacg acaattgcta
     3301 ttcagctgta ctctcgccgg ataaaaaaat gcacggatta cttgttaaaa agaaccatga
     3361 atatgaaatc aaccatgttg atgtagcatt ttcagctttg catggcaagt caggtgaaga
     3421 tggatccata caaggtctgt ttgaattgtc cggtatccct tttgtaggct gcgatattca
     3481 aagctcagca atttgtatgg acaaatcgtt gacatacatc gttgcgaaaa atgctgggat
     3541 agctactccc gccttttggg ttattaataa agatgatagg ccggtggcag ctacgtttac
     3601 ctatcctgtt tttgttaagc cggcgcgttc aggctcatcc ttcggtgtga aaaaagtcaa
     3661 tagcgcggac gaattggact acgcaattga atcggcaaga caatatgaca gcaaaatctt
     3721 aattgagcag gctgtttcgg gctgtgaggt cggttgtgcg gtattgggaa acagtgccgc
     3781 gttagttgtt ggcgaggtgg accaaatcag gctgcagtac ggaatctttc gtattcatca
     3841 ggaagtcgag ccggaaaaag gctctgaaaa cgcagttata accgttcccg cagacctttc
     3901 agcagaggag cgaggacgga tacaggaaac ggcaaaaaaa atatataaag cgctcggctg
     3961 tagaggtcta gcccgtgtgg atatgttttt acaagataac ggccgcattg tactgaacga
     4021 agtcaatact ctgcccggtt tcacgtcata cagtcgttat ccccgtatga tggccgctgc
     4081 aggtattgca cttcccgaac tgattgaccg cttgatcgta ttagcgttaa aggggtgata
     4141 agcatggaaa taggatttac ttttttagat gaaatagtac acggtgttcg ttgggacgct
     4201 aaatatgcca cttgggataa tttcaccgga aaaccggttg acggttatga agtaaatcgc
     4261 attgtaggga catacgagtt ggctgaatcg cttttgaagg caaaagaact ggctgctacc
     4321 caagggtacg gattgcttct atgggacggt taccgtccta agcgtgctgt aaactgtttt
     4381 atgcaatggg ctgcacagcc ggaaaataac ctgacaaagg aaagttatta tcccaatatt
     4441 gaccgaactg agatgatttc aaaaggatac gtggcttcaa aatcaagcca tagccgcggc
     4501 agtgccattg atcttacgct ttatcgatta gacacgggtg agcttgtacc aatggggagc
     4561 cgatttgatt ttatggatga acgctctcat catgcggcaa atggaatatc atgcaatgaa
     4621 gcgcaaaatc gcagacgttt gcgctccatc atggaaaaca gtgggtttga agcatatagc
     4681 ctcgaatggt ggcactatgt attaagagac gaaccatacc ccaatagcta ttttgatttc
     4741 cccgttaaat aaacttttaa ccgttgcacg gacaaactat ataagctaac tctttcggca
     4801 ggaaacccga cgtatgtaac tggttcttag ggaatttata tatagtagat agtattgaag
     4861 atgtaaggca gagcgatatt gcggtcatta tctgcgtgcg ctgcggcaag atagcctgat
     4921 aataagactg atcgcataga ggggtggtat ttcacaccgc ccattgtcaa caggcagttc
     4981 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
     5041 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
     5101 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
     5161 gttaaggagg agactgaaaa tgaagaagtt gttttttttt attgttattg ttattcttaa
     5221 tatacttagg ttatgactac gttaatgaag cactgttttc tcaggaaaaa gtcgaatttc
     5281 aaaattatga tcaaaatccc aaagaacatt tagaaaatag tgggacttct gaaaataccc
     5341 aagagaaaac aattacagaa gaacaggttt atcaaggaaa tctgctatta atcaatagta
     5401 aatatcctgt tcgccaagaa agtgtgaagt cagatatcgt gaatttatct aaacatgacg
     5461 aattaataaa tggatacggg ttgcttgata gtaatattta tatgtcaaaa gaaatagcac
     5521 aaaaattttc agagatggtc aatgatgctg taaagggtgg cgttagtcat tttattatta
     5581 atagtggcta tcgagacttt gatgagcaaa gtgtgcttta ccaagaaatg ggggctgagt
     5641 atgccttacc agcaggttat agtgagcata attcaggttt atcactagat gtaggatcaa
     5701 gcttgacgaa aatggaacga gcccctgaag gaaagtggat agaagaaaat gcttggaaat
     5761 acgggttcat tttacgttat ccagaggaca aaacagagtt aacaggaatt caatatgaac
     5821 catggcatat tcgctatgtt ggtttaccac atagtgcgat tatgaaagaa aagaatttcg
     5881 ttctcgagga atatatggat tacctaaaag aagaaaaaac catttctgtt agtgtaaatg
     5941 gggaaaaata tgagatcttt tattatcctg ttactaaaaa taccaccatt catgtgccga
     6001 ctaatcttcg ttatgagata tcaggaaaca atatagacgg tgtaattgtg acagtgtttc
     6061 ccggatcaac acatactaat tcaaggaggt aaggatggcg gaatgaaacc aacgaaatta
     6121 atgaacagca ttattgtact agcacttttg gggtaacgtt agctttttaa tttaaaaccc
     6181 acgttaacta ggacattgct atactaatga tacaacttaa acaaaagaat tagaggaaat
     6241 tatattggga aaaatattat ctagaggatt gctagcttta tatttagtga cactaatctg
     6301 gttagtgtta ttcaaattac aatacaatat tttatcagta tttaattatc atcaaagaag
     6361 tcttaacttg actccattta ctgctactgg gaatttcaga gagatgatag ataatgttat
     6421 aatctttatt ccatttggct tgcttttgaa tgtcaatttt aaagaaatcg gatttttacc
     6481 taagtttgct tttgtactgg ttttaagtct tacttttgaa ataattcaat ttatcttcgc
     6541 tattggagcg acagacataa cagatgtaat tacaaatact gttggaggct ttcttggact
     6601 gaaattatat ggtttaagca ataagcatat gaatcaaaaa aaattagaca gagttattat
     6661 ttttgtaggt atacttttgc tcgtattatt gctcgtttac cgtacccatt taagaataaa
     6721 ttacgtgtaa gatgtctaaa tcaagcaatc tgatctttca tacacataaa gatattgaat
     6781 gaattggatt agatggaaaa cgggatgtgg ggaaactcgc ccgtaggtgt gaagtgaggg
     6841 gaaaaccggt gataaagtaa aaagcttacc taacactata gtaacaaaga aagcccaatt
     6901 atcaatttta gtgctgagga attggtctct ttaataaatt tccttaacgt tgtaaatccg
     6961 cattttcctg acggtacccc ataaaggaga ataaataaaa tgaataaggt acatgtatat
     7021 aatcataata aatttgtaaa agaaattaat agcgacacga atagcattgc taaagaaatt
     7081 gctagtcaat ccccatttgc tgaattaaaa atgacagatg aatacgataa cttaatttta
     7141 acaacaaaag gctttttcct agatgatgta cctaatcaga tatggctaaa aaatgagtta
     7201 atgccagctc ttacaaattt acagatttaa aaaataacct cacctgatca cattagtata
     7261 attaggtgag gttattttat atattgcgtt gaatattatg tttaatccta tatcttctaa
     7321 atgtttcatg attaatacca gttaaatttt gaacctcttt gtctgaatat ccattcttat
     7381 ataattcaaa agcatgctgt aatctagggc tatcctttgt aaataaaggt tttctacctc
     7441 tatatttttt accgtcttta gcaatcttta ttccctgggc ttgtctttct tttatattct
     7501 ttcgttcaga ttctgcttga tatttatata tttcgggtat tcggatttca tggtggaaaa
     7561 gggcttataa atcacccttc tccaaattct taataagtgt ggaaaaatcg acaccaaagt
     7621 tgtctgtaat gtcgtgatca ttcacttcat accaattgaa agtatcgtat aacatagctt
     7681 tattgaaagc acttgaatta aatcgtggct tacgcttttt atggagcttc tcattgaaaa
     7741 ggattttggc tcgtaaggca tcaaacgagt aacctctacc cattcgctct acctgcctaa
     7801 taatactgtt aattgactcc gtataagcgt tagtgagcct tttatcaaag tagttgaata
     7861 tttcgacatg ccagttgtct acggctctca cgaggtcttt atatgcgtct ttagagttac
     7921 tggacataca acggtgtctc cattgactat aacaaagacg accttcatct ggatcaggag
     7981 tatcccatat ccagtaaaac tcttctttga gttcataggc ttcttttaaa gcaggaagat
     8041 tacctaacca agtatctaag aggaatgatt cacgttcatt tagatcgtgt ttacgcttta
     8101 gaaggataaa cctttcacgc ataagggtac gtctttcttt ttggctcata tgggctttca
     8161 aagactttct gacgttatct aaggcttgat tagccattct aactacatga aacttatcta
     8221 cgacaacttt agcgtgtgga aggatagtgt tcactgcgtc tttgtaaggc ttccacatat
     8281 ccattgtgac gtactcaata taagtcctgt cactgatttc tgaaagacgt tggatgactg
     8341 tttccttgtt acggtttggc ttgatgtcat aaatagtcct gcgttcaata ttagtcaata
     8401 caagccgagg tctacggata atatgtatct cgtctatccc aagccactta ggagtttcaa
     8461 actggtattc acgttctttg agtgccacat agtccttaaa aacgttccta atagttttct
     8521 cgtcaacacc aacgctttct gcgacttcta caaaggtctt agacatggat tgctcttgaa
     8581 tggactttaa aagccttttg gtcatactac gcttttcatc tacagatatt aggcgttccc
     8641 agaaggtaga tccgcattca cgacacttgt atcgtctacg gttcaattgt aagcccactc
     8701 gctttaaacg aatgggcaaa tccataatta gttgatttct tgaactgtgt ttgtacaact
     8761 tgtcaaaacc acattcagga caacgttcag gtggtccgac tgcttcaact ttaaacatca
     8821 tatcggtttc attttcttgt ggtggttcta ttgttttaat gtctggtagg gataataagt
     8881 ctgacatatt gttcatcctt tattactctg cggtgttaag gtatcaatta tagatttgat
     8941 gtcgaaatca tcattgttaa attatttttg tgaccacaaa tgcacttaga aaatccctta
     9001 aagcatttat ataatgggtg atcgcaaaat agtgtatgaa atcttttgta gactttgcta
     9061 aactactgca cacctttagt acagtattag ctggttcact tgaataggga gttgtaaaaa
     9121 aagttccctt agcctgcaca acaagataat ttcgaaacat ctttatcgaa cgtaagtgca
     9181 gctaatttta gcccttcagc cattgttaaa tatggtgcta gggtttctgt taaatcttct
     9241 atcgttaagc caaatttaac agctaatgat gctgcataga tgacatctcc tgcattctca
     9301 gatacaatat gaacccctaa tacttttagt gtttctgcat ctgctactag tttaaataca
     9361 ccggttgttt cacggtttac aattgctctt ggaacagcat ctaaaggtaa tacagatgtc
     9421 ttcacatcat accctttctc ttttgcttgt tcttctgtta aaccaaccgt tgcaaccgtc
     9481 ggattcgtaa acgtaacagc aggaactacc gataaatcta tttttttgtt taatccaccg
     9541 atagcattat cagtaataat tccaccttca taggctgcta catatacaaa ttgcggtcct
     9601 aacgtcacat ctcctgctgc ataaatcttt tcattacttg tttgaccaaa atcattgatc
     9661 aggatttcat tattttttcc agtttcaaca cctgctgcac ttaaatttaa agaatccgta
     9721 tttggttttc ttccagtggc aacaagtaac tgatctgatt caatgacttc tttactgcca
     9781 tttactgtta tgtaaacctt ttttatctct ccactttgtt caacacgctc aaaagttgcc
     9841 cctttgacaa ggtttatacc ctgttcaatt aacgcttttt caactgactc tgaaatctca
     9901 ggatcatact cctttaaaag tcgctcactt ctttgcataa gcgttatttc tgaacctaaa
     9961 tgatgaaata gttgtccaag ctccattcca atgtatcctg agccaattac agttaatcgt
    10021 tttggtattt tctttaactc aagaagtgtt gtactagtta aatagtccat tttttcaagt
    10081 cctgaaattt ggggcaacga aggcgatgca cctgttgcaa ttaaaaagcg ttttgcagat
    10141 aactttgccc cattgacctc aaccgtacta gcatcaacga attttgcttc acctttaatt
    10201 aaatcaaaat tatattcatc aattaaatcc atatattttt gattccgaag ttcgctcacc
    10261 aatttatcct tttgcgtgat taaactagct aaatccactt ctccagcgga tgtttgtaaa
    10321 cctttaaacg gattgtcttt tgataaatga ttgatttccc ctgccctaag aagagttttt
    10381 gacggaacac agccaatatt cacacaggtt cccccaaccg ttccacgctc aatcattcca
    10441 acttttgcac cgtattctat agctttaatt gccgaagaaa aggcagcagc accagaacca
    10501 ataataagaa ggtcataatc atcttcatta attaacgcca cgttttctag tgatgatact
    10561 tcttcaattt ctccggcttg gtaatttgct tcatcaatcg cctttattgc actttcaacc
    10621 tcaatatcat cgggcagttc aaatactgct tcaccacgac gaaaattaga ctcaatattt
    10681 ttagcaccta tcttttcaag tgctgattct acgtgttttt cacaacccgt acaagtcatt
    10741 ccttgaatgt ttaccttaaa tttattcata aaaaagcccc tttcgttaat gtctcatgtt
    10801 aatgtttcta ttattggaca cgaatgtaat tgcttttcat ctggacatcg ttgttttaag
    10861 tcgtctaaca tagtttcaat tcgttttaaa tcctctattt gtttttgcac ttccttttgt
    10921 tttttagaaa caaattcgaa catgtcttga caacgaactt catctttatc tacaacacca
    10981 agtaatttat aaatctcgct taaagaaaaa ctaagttcct gtattcgttt aataaaccca
    11041 acacgcttaa cgtcatcata tgaatatatc cgataaccag cttccgttcg gtgaggttct
    11101 tgtaataaat tttttctctc gtaatatcta atcgtttctt tattaactcc acatttatct
    11161 gcaaactcac taatgcgata aatcatctta tttcacccca tgaatattat aaaccgtgta
    11221 ccatagtacg cggtcaagta aattggacta ttttattttt ccccaacgta tcactcgtat
    11281 gtgattgata cttttatata atactattga ttgtcctaac atcccaccag aaaatccgat
    11341 ttaaacacca gttgttttta aactattaag aaagtaattc cactatatat tccgaagacc
    11401 caaaataaat tttgaaggta atattttaaa agttataaaa gcgacagtaa cagaaatgag
    11461 aggaataaat aatcatcaaa aatacgattt tgatttatat caaatagaag cacgttcgcc
    11521 aatgtcaaca agagaaataa ctttaacagt tgattttata gaaaaaaaag tatcaggtga
    11581 tattatcgct tttggtgatt ggtacgattt ggatatagaa tcagtaaatg aaatattaaa
    11641 gcaattaaaa aaggaaggac aaacattaag aacaatcaat tttatttaaa aaagtatcaa
    11701 aaaaaggaaa attatttttc ctttttttga tactttttag gtttattcgc tttaatatat
    11761 tcagaaaaaa tttttaaaaa ttcttccgtt tcttctacag ttaaatagtc aatttcaaaa
    11821 tacttttcta acaaagcacc tttttcaatt agacgttttg ttcttctttt tctgttaata
    11881 ttttgctcgc tattcgctcg caaaatattt ttttgaattt ttagtttttc tattcttttg
    11941 ttgatgtcat ttaaatcatt atttgccata actatttaag taattcagaa aaattttgac
    12001 tattcgcatt taataaagtt tctaattcgt catagaataa ttctttgttt tcttcaatcg
    12061 attcaataga aatatcaagt tttgaaagag tagaaaggac aaaatcacca atatctgctt
    12121 ttgattttag aattaattct tcttttttct tttgtaattc tttaatttga agttcaatat
    12181 cagaaacagt tttcttcttt ctttttttgg gcttagtttt agaattaaaa ttaccattaa
    12241 ttgcattaat attttgatct tgattttcca tgaaatacgc ctcctaatat attatgtaac
    12301 tctatcatat tatattattt
//
LOCUS       DAXLPQ010000232         7340 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.088, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000232 DAXLPQ010000000
VERSION     DAXLPQ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.088"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(<1..1309)
                     /locus_tag="ACF3UO_002963"
     CDS             complement(<1..1309)
                     /locus_tag="ACF3UO_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3658863.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQK"
     gene            1578..2474
                     /locus_tag="ACF3UO_002964"
     CDS             1578..2474
                     /locus_tag="ACF3UO_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFD3658864.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(2624..3565)
                     /locus_tag="ACF3UO_002965"
     CDS             complement(2624..3565)
                     /locus_tag="ACF3UO_002965"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFD3658865.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            3691..4812
                     /locus_tag="ACF3UO_002966"
     CDS             3691..4812
                     /locus_tag="ACF3UO_002966"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3658866.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5070..6572
                     /gene="eat(A)"
                     /locus_tag="ACF3UO_002967"
     CDS             5070..6572
                     /gene="eat(A)"
                     /locus_tag="ACF3UO_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFD3658867.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            6639..7166
                     /locus_tag="ACF3UO_002968"
     CDS             6639..7166
                     /locus_tag="ACF3UO_002968"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3658868.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         2472 a         1334 c         1481 g         2053 t
ORIGIN      
        1 ttttttgata actgaaataa atgaacaggt aaagcaggcc agtcaataca gttaccccaa
       61 tggagttcgt gaacaggata ccaaggaaaa tcaatcctaa gacagctaat gcaaaaaagc
      121 tgattccttt atcccataat gttccttttc ttagtgccag tacaaaggat gccgcactga
      181 taatgatcca gatcaataat actgtatacg aaagggaacc tgccagatag ccaaataatt
      241 tgtcaccgac aaaataagaa agagctacac caagataaag aacactggta caaaataaaa
      301 cagcacgttg cggtacttga tgcttgttta aaacagctag ttttctagag gaaccttttc
      361 gatccttcaa acggaagaac aaaattcttg aagatgcata cacacccgaa ttgatagatg
      421 agaacaaagc aaggacaatc acaaaattga cgatatccgc tgcaaatggg atattcattt
      481 tttcaaatac catcacaaaa ggactgacat tcgtgcctgc taaagtattc caaggaaaaa
      541 gaatcaaaag caaaaacaaa ggaatgatgt aaaaggaaat gattcttccc atgacacctt
      601 tgattgcttt aggaatcgca cgtttaggat catctgcttc gcttaccgtg atagcaatca
      661 gttcagaacc gccgtaagaa tagataacta caagcaaaga actgatgatt cccttcatac
      721 catgaggagt aaacccacca tggtcagtca attgctgaag ggtagggaaa acgcctgtgc
      781 ccaacatttg ctgaccgaca agataagtag caaaaatgat cagtaagata atgacactga
      841 ttttagcaaa agccagccaa tattctgttt ctgcgaataa ccgtaccgaa taaagattga
      901 tgatcgtagt taaaacagcc aacataaaaa caaataccca ggctggaatg tgcgggaacc
      961 acaactgcaa aaaggaagca gctgcaacag cttcagcgat gatattgata atccacatag
     1021 accagtagac ccaatcagta aaatcagcag aatgagcacc tagataaggg cgtatcaaac
     1081 cagataatcc gtgatgcgtg tcgccaccgc ttaaaacgat ttttcccaga cctttcatca
     1141 cgatatataa aatcagccca ccaatcaaaa aagcaatcaa tacagaaggg ccggcgatcc
     1201 caatcgcttc gccacttcct ttaaatagac ctgcaccgat tgctccacct aaagctaaca
     1261 tggtgatatg tctggagcta agttgttttt tcaatttttt atcttccata aatgacctct
     1321 ttcttttaaa ttcacaatca aaatttatat taagaataaa tagcaatatt taacaatgac
     1381 taatgataac aaattttcag acaattacaa ctattcagaa aacttttagg cgaattttaa
     1441 tagaagaatg atttatttca tcatattttc atacaaatgt taaattttca tacaaatata
     1501 ggaaacgttt tactggcttt ttactattta aacaggctat cataggaaaa agtgacagag
     1561 aaagtgaggc ggaaaagatg aacaaaaatg acgtactgct agttgcaaaa aataaatcac
     1621 tttatttttt gccttccatc cgctctttag atgtttggtc cggaaaagat ttactacagt
     1681 cggaattcat taaatcagct agacaacagt tggcaaatta tcagctgatc gtttttttag
     1741 attatggatt tgatatggag atggctcgac gcgtgcgccc atttaccaat gcaaaaattg
     1801 tgttattttt ttggaatcac ttcaaagcag aacacgaggc gatgctgaag caggcacaag
     1861 atgaaccggc aatcgatgag atttatcatt ttgatttttt ggaagcaaaa gaacttgggc
     1921 tgaaacataa tagttcattt tattcgaaac atatgaattt ttcttctagc gaaccaaaga
     1981 cggatctatt ttttggtgca acgaataatg ggagaaaaga acgagcagaa agctataagc
     2041 aggaatttat aaaaagagat gttacgacca actatttcat tcttccacat cgagggaatg
     2101 aacaacctgg atatcttact tatgaagagt acctgaaaaa aacaggggaa tcgcgcggga
     2161 ttctggaact gttgcgggag ggtcagcaag gagtgacttt gcggacattt gaatccatgt
     2221 attttcaaaa gaaactagtg acggataatc aagcgattgc tcattatcat ttttatcgtc
     2281 ctgaaaatat ttttttgctt cgagaacgtg atttagatga attaccggaa tttctgcata
     2341 caccatttaa gccaatccta tcagagctat tggaatttta tgatgcagaa aattgggcaa
     2401 aacgatttat cactaacgat tccactattt atgagcaata cgaatatgac ctctcctctg
     2461 ttgaaaacaa ataaaaaacc tacattttga agagattatg tactgaaaca aacaagcaca
     2521 attcttatgg catcatgaga gttgtgtttt ctttttgatc ttttattggg cttaaaaaaa
     2581 gagaaccagc tgctgattca gctgattctc atcagagagc cttttattct gcgccaagga
     2641 ttccttcttt tgcatggact aattgggtca aaaaggcaca atatggtgta gcaatatcat
     2701 atttttgtcc ttttcgccaa atggcaccat tgatgtagtc gatttcagtc aaacgatggt
     2761 ttttgatcag gtcttggtac atagatgggt aatgcaaccc gatgttgtca ggatcataag
     2821 tagaagcaat atgttggtac acttcttctt gatctagtat gattccttct tttgctgcga
     2881 tagaagcaaa ttcagatacg attgttcgaa ccatgctctc tgccgctttt tgcgcgccta
     2941 gttcagcaat attacaatcc aaaatcgtgc ataaaccatt caatgttcca tttacacaag
     3001 cttttcgcca aatggaataa cgaacgttat ggctatagat cggatttaaa tttgcttctt
     3061 gaaagacttc tacaactttt tttgtaaatg cttcgccttc tggttccaag ttctctagtt
     3121 cgatttctcc atcacctaac aatgtgactt ttccgggacc agctagacca gctgtccaca
     3181 tcgtgatccc aaataagata tttttctttg gcacatattt ttccagtaca tcttcatgac
     3241 ctaatccatt tagtaaacac aaaacataag tattgtcagt aataatggat tggatcgaac
     3301 aaaacatatc atctaattga ttggcttttg ttaatgctac gatcaagtcc acgtgttcgt
     3361 tgctttcgat gatttcttct ggtgaataga ttggcagttt tgcgaccact tctttaccgt
     3421 taaagtcagc aatcaaccca tttgtacgaa tggcttcaat gtgagcaggc caacgatcga
     3481 tcaagaggac ctcatttccg ctttgatgta gcatcaatcc gattcggctg cccattgctc
     3541 cggccccagc tattgcgatt ttcatgtttt ttctctcctt tattcaatga gttccctttt
     3601 agtatataga aaaatggaag aaaatagcat tgttttgttt gaaaaaaatg aaaaaaagtg
     3661 tcttacttaa gaagaaagtg agggatacag atggatattt tggcggcaat tgattcattt
     3721 aaaggaagtg cttcttcatt tgaactaaat caggcagttc taaatggctg ggaagatcgt
     3781 aaaggaagaa aaatcaatgt gccgattgca gatggcggag aaaatactgc agaagcaatc
     3841 tattacgcgc tcaggggaac atggcgtacc attgatggga tggatctctt attccgtcag
     3901 cgaaaaatca gctatttatt gacaacttgg caaggaaaaa acaccgcagt catcgaatct
     3961 gcacaagcat tggggttaga tctacttgat aaaccaacgg atcaaactat ccgacttgct
     4021 tccagttatg ccttaggaga acttattaaa gatgcactgc ttcaagaagt agaacaaatt
     4081 attgtcactt taggaggaag cgggtgtagc gatggtggtc taggattact ccaatccttg
     4141 ggtgcttctt tagaagggta cacagaagga aatcctttat tatctactaa aaaacttcat
     4201 tttgatcgaa gaaacgttct tgtttctaaa gtaaaattga ttatcgctgc agatgttacc
     4261 aatccatata caggtcaaca aggagctgct tggcaatttg gaagacaaaa aggaggaata
     4321 gatacgacgc tagctttctt agataaacaa gcaggaaaga ttgctcagca aataaaagat
     4381 ttctgggagg tggatttaga tgatattcca ggaagtggag cagcaggcgg tattggtgga
     4441 gccctttttt tgttgggagc gaagatggtt tctggtttcg atttagtcag ccaaatcact
     4501 ggattggaaa aaaagatcga acaagcagat gtcatcatta caggagaagg gcggatcgat
     4561 cagcaaacga tccacggaaa agttccatac ggtgtagcag tgcttgcaaa aaaatatcga
     4621 aaaccaataa tcgctatttg cggaagtaga gaccaagagc tagaaggact ttctgatttt
     4681 ctcccaattg tcttaagtat tcatttgggt ccaataggtt tagaagaagc aatggaacac
     4741 aggcaaacat tagaaaaaac aaaaatctta ggacagacac ttagcagatt tttcaccatc
     4801 ctcccgaagt agttgacaaa atcattttct ttatgctatc gtaatttcaa atataggaca
     4861 aagtgaggga tccgtgcatt gaaaaattaa gtcgattgat gaaagctgca ttcagactgt
     4921 accttgtgga gacaaggaag cagtgtgcag attttcggga ttggcttggt tttttcgatg
     4981 tatgggtctt tttgtgtgta tccaaccctt gcatcctctt tagccagttc tgaaaatagg
     5041 actggtcttt ttttacgagg tgatggaaaa tgtctaaaat cgaaataaaa aatctgacat
     5101 tcggctacga cagccaaggc acattattat ttgaacaagc aaatctaaat tttgacacac
     5161 aatggaaact aggacttatc ggacgaaacg gtcgaggaaa gacaacttta ctgaatattc
     5221 tacaaaacaa actaccttat caagggcaag taatccatca gcaagaattt gcctatttcc
     5281 cgcaacagac aaaagataaa gaacgtttaa cctattacgt gttaaatgat attacggatt
     5341 ttgagatatg ggaaatcgaa agagagctcc aattgatgca aacagatcct gaaatcttat
     5401 ggagagaatt cagcacacta tcggggggag agaagacaaa agtcctactg gcacttttat
     5461 ttgtggatga cactcatttc ccgttaatcg atgaaccaac gaatcatttg gatatctctg
     5521 gtagaaaaca agtagcggct tatttgaaaa agaaaaaaca aggcttcatc gtggtcagcc
     5581 atgaccgggg atttatcgat gaagtagtgg accatgtttt agcaatcgaa aaaagtcaac
     5641 tggaacttta tcaagggaat ttctctatct atgaagaaca gaaaaaactt cgtgatgaat
     5701 ttgaaatggc tcaaaatgaa aaattgaaaa aagaagtcag taggctaaag aaaacagcag
     5761 ctgaaaaagc cgaatggtct cgttcccgag aaggagataa aacaaagaaa caagtcggat
     5821 tcatcgatac tgaatctaga cgagtgaata aaggagcagt gggtgctgat gctgcacgga
     5881 cgatgaaacg atccaaagca atcgtgaatc ggatggagac ccagatcagc gagaaagaaa
     5941 aactattaaa agatatcgaa tatatcgatt ctttgacgat gaatagccaa gcgtctcacc
     6001 ataagcgact tttaagcgta gaagatcttc aattagggta tgaaaatctg ttattcgagc
     6061 caattcattt tacaatcgag cctcatcagc gggtggcgat ttcaggtcct aacggtgcag
     6121 gaaagtcatc cattatccat tatcttctgg gggcattcaa cggcaaggtt ataggagaaa
     6181 aataccagcc aaaacatctg agcattagtt atgcaagcca aaattatgaa gacaatcgag
     6241 gaacgttggc ggaatttgca gagaaaaacc aagtagacta ccaagcattt ttgaacaacc
     6301 tccgaaagct tgggatggaa agagatgttt ttcataacaa gatcgagcag atgagtatgg
     6361 gccaacggaa aaaagtggaa ttggctaaat ctttatcaca gccagctgaa ctatatacat
     6421 gggatgaacc attgaattat ttggatgtct tcaatcaaga acaattagaa caactgatct
     6481 tgaacgtgaa acctgccatg ttactagtgg aacatgatca aaccttcctg gataaagtat
     6541 ctactgagat tatttctctt gagagaatct aacccttgta atctcaagaa caacaaggta
     6601 tggttaaggg gaactttgcc aacgaaggag agaatcacat gctttatgta acgagacacg
     6661 gagaaacaac ttggaacgca caaggattag tttgcggacg ggcagatgtg ccgctgactg
     6721 aaaaaggaca gatgcaggca cagaaactag cagaaaaggt agtagatttg cctgttccaa
     6781 tcacgaaaat catccattcc cctcttcaac gagcaagaga tacagcacaa gcagttgctg
     6841 atcgtctcag cttgccgctg accgttgatg aacgattggt agaaatggat tttggggatt
     6901 atgatggact gccaagcaaa gatgagaact ttcaaaaagc acgtttagcg ttcgctgtac
     6961 gattcccaaa tggggagtca gtcttagatg tgtatgcacg gatcgttcct ttattgaaag
     7021 aatgcatcga agacgaagaa aatgtctatc tgttagtttg ccataatgcc ttgataagag
     7081 tgatcaatgc ttattttcat ccgatgccta atgaggggtt ctttacattc atggtagata
     7141 atacagaatt ggtttcttat gagtaattat gtttttgtgt tatttaaata aaatatttca
     7201 aggcactgct tttgcttagc agtgcctttt ttaggttatg acaattcttt tgataatata
     7261 aactcaacct ttagaaatga aatttaatta ttttaataaa agtattgaaa ttttgtttct
     7321 ttagatatat actctagtca
//
LOCUS       DAXLPQ010000233         3719 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.120, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000233 DAXLPQ010000000
VERSION     DAXLPQ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.120"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(530..655)
                     /locus_tag="ACF3UO_002969"
     CDS             complement(530..655)
                     /locus_tag="ACF3UO_002969"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658869.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            640..2580
                     /gene="tet(S)"
                     /locus_tag="ACF3UO_002970"
     CDS             640..2580
                     /gene="tet(S)"
                     /locus_tag="ACF3UO_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3658870.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            2668..2835
                     /locus_tag="ACF3UO_002971"
     CDS             2668..2835
                     /locus_tag="ACF3UO_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFD3658871.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(3349..3705)
                     /locus_tag="ACF3UO_002972"
     CDS             complement(3349..3705)
                     /locus_tag="ACF3UO_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3658872.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
BASE COUNT         1327 a          577 c          618 g         1197 t
ORIGIN      
        1 atttgatagt agatttaaaa ctttgcaaca gaaccctttt aatgatattt tccaagtcaa
       61 acttaatatt aacaattcaa aactattgga accactgcaa aatattttgt taagcagtat
      121 atatttcaaa aattatacgt aatatatttg tagaaaggtt gtggacagtt gtcctattga
      181 cctgaaaagt aatataatag ctggatgaat aaagaatccc ttatgaactt gtaaatcgtt
      241 attaaatcgc tgaattttga tagccattct gaagagttat cttcaactac tacactaact
      301 tccattaatt tctcattaat ttccctttcg ttcaaaaaat atggttggct ttacaagcat
      361 tctatcatat gatagaatta agataacatt caaaaggaga taataaaaat gcggcaaggt
      421 attcttaaat aaactgtcaa ttagatagcg ggaataatta attaagcatc cttatttaaa
      481 ataaggactg gttttttgtg cccagtttaa gaatactttt atcattttat cataaagcat
      541 ctgtggctat cagtgtgtag tatacagcta tttttgtatt aaaatcccag tgataagagt
      601 atttatcact gggatttttt ctgctttttg agcttttgaa tggaggaaat aaaattgaaa
      661 attattaata tcggtatctt agcacatgtt gatgcaggaa aaactacttt gacagaaagc
      721 ttactataca gtagcggagc aattaaagag ttaggaagtg tagatagcgg tacaacgaaa
      781 acggatacta tgtttttgga acgccagaga ggtattacta ttcagaccgc aataacatct
      841 tttcaacggg aaaatgttaa agtaaatatt gtagatactc ctggacacat ggattttttg
      901 gcagatgtat accgttcatt atctgttttg gatggagcta ttttgctaat ctctgcaaaa
      961 gatggagtac agtcacaaac tcgtatacta ttccatgcac ttagaaagat gaacatacct
     1021 ataatatttt ttattaacaa aattgatcaa aatggaataa atttgccaga tgtttatcaa
     1081 gatattaagg acaaactttc tgacgacatc ataattaagc agactgtgaa tctaaatttg
     1141 aaaccttatg taatagatta tactgaacca gaacaatggg agacagtaat tgtgggaaat
     1201 gattatttat tagaaaaata taccattggg aaaacattga atattgcaga acttgaaaag
     1261 gaggaaaacg aaagaattca aagttgctcc ttatatcctg tttatcacgg aagtgcaaag
     1321 aataatattg gaattaaaca acttatagag gtaattacta gcaaattatt ttcacccaca
     1381 caactcaatt cagataaact ttgtggaaat gtttttaaag tagaatattc agatgatggt
     1441 caacggcttg tctatgtacg tctttatagt ggaacgctac atttgcgaga ctcagtcaat
     1501 atatcagaaa aggaaaaaat aaaagttaca gaaatgtata cttcaataaa tggagaatta
     1561 cgccagatag ataaggcaga gcctggtgag attattattt taaaaaatga gcttttaaaa
     1621 ctaaataacg tacttggaga taaaaaaaga ttaccacata gagaaattct tgagaatcct
     1681 cttcctatgt tacaaacaac aattgaacca tgtaaatcag tacaaagaga aaagttacta
     1741 gatgcacttt ttgaaatatc cgatagtgat ccccttctac aatattatgt agatacagta
     1801 actcacgaaa ttgtgctatc ttttttaggt gaggtccaaa tggaggtaac ttgtactctg
     1861 attcaagaaa aatatcatat tgagatagaa acaagaaaac caactgtcat ttatatggaa
     1921 agaccattaa aaaaatctga atttaccatt gatatcgaag tacctccaaa tcctttctgg
     1981 gcttctattg gtttatctgt aacaccactt cctttgggta gtggcattca gtatgagagc
     2041 ctggtttctc taggttattt aaatcaatca tttcaaaatg cagttatgga aggtatacgc
     2101 tatgggtgtg aacaaggatt gtacggttgg aaattaacag actgtaagat ctgttttaag
     2161 tatggtctat attacagccc tgtcagtacg ccagcagatt tccgaatgct tgcgcctatt
     2221 gtactagagc aggcttttag aaagagtggt acagagttat tagagccata tcttagcttc
     2281 gaaatttatg taccacaaga atatctttcg agagcatata atgatgcttc caaatattgt
     2341 gcaaatattt taaatactaa gttaaaaggt aacgaggtca ttctcattgg tgaaattcca
     2401 gcccgttgta ttcaagagta tcgaaacagt ttaactttct ttacaaatgg acgcagtgtc
     2461 tgtttaacag agttaaaagg ttatcaggtt actaacatta agtctgcttt ccaaccacgt
     2521 cgtccaaata atagaataga caaagtaagg catatgttta ataaaatcaa cttacattga
     2581 tagtgaacta aagagaaatt tttaaaatga atattgagtt gttaattaga acaggaggat
     2641 atagatattg taaatactag gtggatactg tgccctatat gtggcaataa gacccgttta
     2701 aaaatgaggg aagatactga attaaaaaat ttccctctat tttgtcctaa atgcagacaa
     2761 gaaattttaa ttgaaataac gaagtttaga ataactgtaa ttacagagcc agacgcaaag
     2821 acgcagagcc gataattcga gatatcaaaa tctcatttta tcggcttttt cttttctatg
     2881 cataccattg agcttagttc ttgatatcct ttataagaaa ataagtgtac tgattttttt
     2941 tgcagtagct gtattacagt agacatccct caagcataaa aagtatacaa ttaaaattca
     3001 atacttgatt attgatgaag tacagagtta ctcgtcattt caaaactagt atatcagtca
     3061 agtttttcct aaggaacaaa aacgaacttc gctatgggaa tcaaaaattt ttagtcggat
     3121 gaagtgatat gcaataaatc cagaaaattt tcccaacaac aaaaaatgaa ctgtactttg
     3181 cagcgataag agtaaccaaa gaactattta tcattcgctc tagttcctaa gtgtaacaaa
     3241 gataaattca ttttctattt atgattaaca aaaatcagaa aaaattcatt acatctttgt
     3301 aatcaatctt tcctgatagt attaattaat ccattgtgta ttattgaact agttaaattt
     3361 acatttttct ccgtaaattg cttgaatcac tttcccaatc gtcactaatt catcttcatc
     3421 cagacaatcc aactgtgctt ctacttgaag acgtttggag cttttatgac tgttttcttc
     3481 ccctaaaata aatccatcca aagaaatatt tagcaaagtc actaaatcat atacaacatg
     3541 aaaacttggc tgttgtcctt tattttcaat gttcgtcaaa tagcgtggcg caatctggat
     3601 cattgatcct acctgctcac gagtcaatcc tttactaaga cgggcttctt taatcgcaag
     3661 acccaatggt ttgaaatcaa aatttgatag agtagtttgc catattcttg cacccaacg
//
LOCUS       DAXLPQ010000234         2596 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.133, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000234 DAXLPQ010000000
VERSION     DAXLPQ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.133"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..173
                     /locus_tag="ACF3UO_002973"
     CDS             <1..173
                     /locus_tag="ACF3UO_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3658873.1"
                     /translation="KYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMDIPGMADEMRR
                     PMMLIVSAKKKM"
     gene            206..1114
                     /locus_tag="ACF3UO_002974"
     CDS             206..1114
                     /locus_tag="ACF3UO_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFD3658874.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1111..1653
                     /gene="sat4"
                     /locus_tag="ACF3UO_002975"
     CDS             1111..1653
                     /gene="sat4"
                     /locus_tag="ACF3UO_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFD3658875.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            1746..2540
                     /locus_tag="ACF3UO_002976"
                     /note="aph(3')-IIIa"
     CDS             1746..2540
                     /locus_tag="ACF3UO_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFD3658876.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          885 a          403 c          609 g          699 t
ORIGIN      
        1 caaaatatca tagaacactg accacatatc taaatacact gctttcaaat agttttataa
       61 taaatcagat tgtggagcca cagccgccag agaacatgat ggatattccg gggatggcgg
      121 atgaaatgcg acgcccaatg atgctgattg tatcggcaaa aaagaagatg taataatata
      181 gaaaaaataa acgaggagta tgtaaatgag atcagaaaaa gaaatgatgg atttagtact
      241 ttctttagca gaacaggatg aacgtattcg aattgtgacc cttgaggggt cacgcgcaaa
      301 tattaatata cctaaagatg aatttcagga ttatgatatt acatattttg taagtgatat
      361 agaaccgttt atatctaatg atgactggct taatcaattt gggaatataa taatgatgca
      421 aaagccggag gatatggaat tattcccacc tgaagaaaag ggattttcct atcttatgct
      481 atttgatgat tacaataaaa ttgatcttac cttattgccc ttggaagagt tagataatta
      541 cctaaagggc gataaattaa taaaggttct aattgataaa gattgtagaa ttaaaaggga
      601 catagttccg actgatatag attatcatgt aagaaagcca agcgcaaggg agtatgatga
      661 ttgctgcaat gaattttgga atgtaacacc ttatgttatt aaaggattgt gccgtaagga
      721 aattttattt gctattgatc attttaatca gattgttcgc catgagctgc tgagaatgat
      781 atcatggaag gtcggcatcg aaacaggctt taaattaagt gtaggcaaga actataagtt
      841 tattgaaagg tatatatccg aggatttgtg ggagaaactt ttgtccacct accggatgga
      901 ttcctatgaa aacatatggg aagcattatt tctatgccat caattgttca gggcggtatc
      961 cggtgaggtg gcggaaaggc ttcattatgc ctatccggag tatgatagga atataacaaa
     1021 atataccagg gacatgtata aaaaatacac tggtaaaacc ggctgcctgg atagcacata
     1081 tgccgctgat atagaagaga ggcgggaaca gtgattacag aaatgaaagc agggcacctg
     1141 aaagatatcg ataaacccag cgaaccattt gaggtgatag gtaagattat accgaggtat
     1201 gaaaacgaga attggacctt tacagaatta ctctatgaag cgccatattt aaaaagctac
     1261 caagacgaag aggatgaaga ggatgaggag gcagattgcc ttgaatatat tgacaatact
     1321 gataagataa tatatcttta ctaccaagac gataaatgcg tcggaaaagt taaactgcga
     1381 aaaaattgga accggtacgc ttatatagaa gatatcgccg tatgtaagga tttcaggggg
     1441 caaggcatag gcagcgcgct tatcaatata tctatagaat gggcaaagca taaaaacttg
     1501 catggactaa tgcttgaaac ccaggacaat aaccttatag cttgtaaatt ctatcataat
     1561 tgtggtttca aaatcggctc cgtcgatact atgttatacg ccaactttga aaacaacttt
     1621 gaaaaagctg ttttctggta tttaaggttt tagaatgcaa ggaacagtga attggagttc
     1681 gtcttgttat aattagcttc ttggggtatc tttaaatact gtagaaaaga ggaaggaaat
     1741 aataaatggc taaaatgaga atatcaccgg aattgaaaaa actgatcgaa aaataccgct
     1801 gcgtaaaaga tacggaagga atgtctcctg ctaaggtata taagctggtg ggagaaaatg
     1861 aaaacctata tttaaaaatg acggacagcc ggtataaagg gaccacctat gatgtggaac
     1921 gggaaaagga catgatgcta tggctggaag gaaagctgcc tgttccaaag gtcctgcact
     1981 ttgaacggca tgatggctgg agcaatctgc tcatgagtga ggccgatggc gtcctttgct
     2041 cggaagagta tgaagatgaa caaagccctg aaaagattat cgagctgtat gcggagtgca
     2101 tcaggctctt tcactccatc gacatatcgg attgtcccta tacgaatagc ttagacagcc
     2161 gcttagccga attggattac ttactgaata acgatctggc cgatgtggat tgcgaaaact
     2221 gggaagaaga cactccattt aaagatccgc gcgagctgta tgatttttta aagacggaaa
     2281 agcccgaaga ggaacttgtc ttttcccacg gcgacctggg agacagcaac atctttgtga
     2341 aagatggcaa agtaagtggc tttattgatc ttgggagaag cggcagggcg gacaagtggt
     2401 atgacattgc cttctgcgtc cggtcgatca gggaggatat cggggaagaa cagtatgtcg
     2461 agctattttt tgacttactg gggatcaagc ctgattggga gaaaataaaa tattatattt
     2521 tactggatga attgttttag tacctagatt tagatgtcgg ttctgttgca aagttttaaa
     2581 tctactatca aataag
//
LOCUS       DAXLPQ010000235         2566 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.134, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000235 DAXLPQ010000000
VERSION     DAXLPQ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.134"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            complement(39..341)
                     /locus_tag="ACF3UO_002977"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACF3UO_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACF3UO_002978"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACF3UO_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1055..1345)
                     /locus_tag="ACF3UO_002979"
     CDS             complement(1055..1345)
                     /locus_tag="ACF3UO_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3658877.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..2245)
                     /locus_tag="ACF3UO_002980"
     CDS             complement(1553..2245)
                     /locus_tag="ACF3UO_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3658878.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          759 a          472 c          357 g          978 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt gcttcgtcta
     1681 atttcttttg tgtatctgtt aactgagttt ctacatttgt tttttcttgt gtcagtgttg
     1741 cgatttgttg attcaaacca tttacagtat tttgtaattc tgaaagtttt gcttgtgctt
     1801 cttgtagtct tgctgtccaa tctgcattca gatgattgat ttcatcattt ttttggttga
     1861 tctcatctag tttgacattg atttcatttt gtttgctttg tagttgtgca tccttgctga
     1921 ctaattgact ttctaagttt tgtttttctg ctgccgattg atttttttgg ttttctaatt
     1981 catttacttt tgtttggtat tcttggacat ctgcctttga atcttgcaat gtctgttctt
     2041 tttgtgctag tcgagcggta agatctgtaa tcgcttgctc tttatctgtc aatgtatgat
     2101 caagctgtgt cagattctca ttgattgtat caatatctgt ctctccaccc cacaaaataa
     2161 tttcatttgc gtaccgcgtg cctgtgtagc caattagaca tagaaatgca acgacaatcc
     2221 caccagtaat aaatttcttt ttcatttgca tagctcctta atccaatact tttacatgct
     2281 aaaagtaagt gatctcaaac acaatgtcaa gcgtttttaa attacatatg taattttaat
     2341 ataaatacta tcaaatactc atttaatcct ccttttttat ctatttaaaa aatctttttt
     2401 atagagaaaa atgcaggtta atactttctt aaataaatat ttatggtgaa caaaaacaaa
     2461 aaagcaagtt ttattaaacg taaccctttt catttcatag attactgtat ttattacaaa
     2521 aaacgcggat ttgtcataaa ttgtcatgct tcttttacct atgaaa
//
LOCUS       DAXLPQ010000236         1934 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.149, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000236 DAXLPQ010000000
VERSION     DAXLPQ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.149"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            45..437
                     /locus_tag="ACF3UO_002981"
     CDS             45..437
                     /locus_tag="ACF3UO_002981"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3658879.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDDIVYVYDYEKGDK"
     gene            438..1877
                     /locus_tag="ACF3UO_002982"
                     /note="aph(2'')-Ia"
     CDS             438..1877
                     /locus_tag="ACF3UO_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFD3658880.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          801 a          145 c          332 g          656 t
ORIGIN      
        1 cattgtatag cattttacac aggagtctgg acttgactga gtttatggaa gaagttttaa
       61 ttgatgataa tatggttttt gatattgata atttaaaagg atttcttaat gataccagtt
      121 catttgggtt tatagctaaa gaaaataata aaattatagg atttgcatat tgctatacac
      181 ttttaagacc tgatggaaaa acaatgtttt atttacactc aataggaatg ttacctaact
      241 atcaagacaa aggttatggt tcaaaattat tatcttttat taaggaatat tctaaagaga
      301 ttggttgttc tgaaatgttt ttaataactg ataaaggtaa tcctagagct tgccatgtat
      361 atgaaaaatt aggtggtaaa aatgattata aagatgatat agtatatgta tatgattatg
      421 aaaaaggtga taaataaatg aatatagttg aaaatgaaat atgtataaga actttaatag
      481 atgatgattt tcctttgatg ttaaaatggt taactgatga aagagtatta gaattttatg
      541 atggtagaga taaaaaatat acattagaat cattaaaaaa acattataca gagccttggg
      601 aagatgaagt ttttagagta attattgaat ataacaatgt tcctattgga tatggacaaa
      661 tatataaaat gtatgatgag ttatatactg attatcatta tccaaaaact gatgagatag
      721 tctatggtat ggatcaattt ataggagagc caaattattg gagtaaagga attggtacaa
      781 gatatattaa attgattttt gaatttttga aaaaagaaag aaatgctaat gcagttattt
      841 tagaccctca taaaaataat ccaagagcaa taagggcata ccaaaaatct ggttttagaa
      901 ttattgaaga tttgccagaa catgaattac acgagggcaa aaaagaagat tgttatttaa
      961 tggaatatag atatgatgat aatgccacaa atgttaaggc aatgaaatat ttaattgagc
     1021 attactttga taatttcaaa gtagatagta ttgaaataat cggtagtggt tatgatagtg
     1081 tggcatattt agttaataat gaatacattt ttaaaacaaa atttagtact gataagaaaa
     1141 aaggttatgc aaaagaaaaa gcaatatata attttttaaa tacaaattta gaaactaatg
     1201 taaaaattcc taatattgaa tattcgtata ttagtgatga attatctata ctaggttata
     1261 aagaaattaa aggaactttt ttaacaccag aaatttattc tactatgtca gaagaagaac
     1321 aaaatttgtt aaaacgagat attgccagtt ttttaagaca aatgcacggt ttagattata
     1381 cagatattag tgaatgtact attgataata aacaaaatgt attagaagag tatatattgt
     1441 tgcgtgaaac tatttataat gatttaactg atatagaaaa agattatata gaaagtttta
     1501 tggaaagact aaatgcaaca acagtttttg agggtaaaaa gtgtttatgc cataatgatt
     1561 ttagttgtag tcatctattg ttagatggca ataatagatt aactggaata attgattttg
     1621 gagattctgg aattatagat gaatattgtg attttatata cttacttgaa gatagtgaag
     1681 aagaaatagg aacaaatttt ggagaagata tattaagaat gtatggaaat atagatattg
     1741 agaaagcaaa agaatatcaa gatatagttg aagaatatta tcctattgaa actattgttt
     1801 atggaattaa aaatattaaa caggaattta tcgaaaatgg tagaaaagaa atttataaaa
     1861 ggacttataa agattgatta tataatatat gaaaagctat tataaaagac attagtatta
     1921 aatagtttaa aaaa
//
LOCUS       DAXLPQ010000237         1772 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.153, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000237 DAXLPQ010000000
VERSION     DAXLPQ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.153"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            277..330
                     /locus_tag="ACF3UO_002983"
                     /pseudo
     CDS             277..330
                     /locus_tag="ACF3UO_002983"
                     /inference="COORDINATES: protein motif:HMM:NF019662.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            364..1740
                     /gene="tet(L)"
                     /locus_tag="ACF3UO_002984"
     CDS             364..1740
                     /gene="tet(L)"
                     /locus_tag="ACF3UO_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFD3658881.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
BASE COUNT          518 a          262 c          354 g          638 t
ORIGIN      
        1 ggtgtattca agaatatcgt agtgatttaa ctttctttac aaatggacgt agtgtttgtt
       61 taacagagtt aaaagggtac catgttacta ccggtgaacc tgtttgccag ccccgtcgtc
      121 caaatagtcg gatagataaa gtacgatata tgttcaataa aataacttag tgtattttat
      181 gttgttatat aaatatggtt tcttgttaaa taagatgaaa tattttttaa taaagatttg
      241 aattaaagtg taaaggagga attaattatg aagtgaaatg aatgtaacag ggttcaatta
      301 aaagagggaa gcgtatcatt aaccctataa actacgtctg ccctcattat tggagggtga
      361 aatgtgaata catcctattc acaatcgaat ttacgacaca accaaatttt aatttggctt
      421 tgcattttat ctttttttag cgtattaaat gaaatggttt tgaacgtctc attacctgat
      481 attgcaaatg attttaataa accacctgcg agtacaaact gggtgaacac agcctttatg
      541 ttaacctttt ccattggaac agctgtatat ggaaagctat ctgatcaatt aggcatcaaa
      601 aggttactcc tatttggaat tataataaat tgtttcgggt cggtaattgg gtttgttggc
      661 cattctttct tttccttact tattatggct cgttttattc aaggggctgg tgcagctgca
      721 tttccagcac tcgtaatggt tgtagttgcg cgctatattc caaaggaaaa taggggtaaa
      781 gcatttggtc ttattggatc gatagtagcc atgggagaag gagtcggtcc agcgattggt
      841 ggaatgatag cccattatat tcattggtcc tatcttctac tcattcctat gataacaatt
      901 atcactgttc cgtttcttat gaaattatta aagaaagaag taaggataaa aggtcatttt
      961 gatatcaaag gaattatact aatgtctgta ggcattgtat tttttatgtt gtttacaaca
     1021 tcatatagca tttcttttct tatcgttagc gtgctgtcat tcctgatatt tgtaaaacat
     1081 atcaggaaag taacagatcc ttttgttgat cccggattag ggaaaaatat accttttatg
     1141 attggagttc tttgtggggg aattatattt ggaacagtag cagggtttgt ctctatggtt
     1201 ccttatatga tgaaagatgt tcaccagcta agtactgccg aaatcggaag tgtaattatt
     1261 ttccctggaa caatgagtgt cattattttc ggctacattg gtgggatact tgttgataga
     1321 agaggtcctt tatacgtgtt aaacatcgga gttacatttc tttctgttag ctttttaact
     1381 gcttcctttc ttttagaaac aacatcatgg ttcatgacaa ttataatcgt atttgtttta
     1441 ggtgggcttt cgttcaccaa aacagttata tcaacaattg tttcaagtag cttgaaacag
     1501 caggaagctg gtgctggaat gagtttgctt aactttacca gctttttatc agagggaaca
     1561 ggtattgcaa ttgtaggtgg tttattatcc atacccttac ttgatcaaag gttgttacct
     1621 atggaagttg atcagtcaac ttatctgtat agtaatttgt tattactttt ttcaggaatc
     1681 attgtcatta gttggctggt taccttgaat gtatataaac attctcaaag ggatttctaa
     1741 atcgttaagg gatcaacttt gggagagagt tc
//
LOCUS       DAXLPQ010000238          991 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.179, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000238 DAXLPQ010000000
VERSION     DAXLPQ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.179"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UO_002985"
     CDS             44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UO_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3658882.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          358 a          173 c          168 g          292 t
ORIGIN      
        1 ttctgtattt gtttatagat gtaatcactt caggagtgat aacatgaaca aaaatataaa
       61 atattctcaa aactttttaa cgagtgaaaa agtactcaac caaataataa aacaattgaa
      121 tttaaaagaa accgataccg tttacgaaat tggaacaggt aaagggcatt taacgacgaa
      181 actggctaaa ataagtaaac aggtaacgtc tattgaatta gacagtcatc tattcaactt
      241 atcgtcagaa aaattaaaac tgaatactcg tgtcacttta attcaccaag atattctaca
      301 gtttcaattc cctaacaaac agaggtataa aattgttggg aatattcctt accatttaag
      361 cacacaaatt attaaaaaag tggtttttga aagccgtgcg tctgacatct atctgattgt
      421 tgaagaagga ttctacaagc gtaccttgga tattcaccga acactagggt tgctcttgca
      481 cactcaagtc tcgattcagc aattgcttaa gctgccagcg gaatgctttc atcctaaacc
      541 aaaagtaaac agtgtcttaa taaaacttac ccgccatacc acagatgttc cagataaata
      601 ttggaagcta tatacgtact ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt
      661 tactaaaaat cagtttcatc aagcaatgaa acacgccaaa gtaaacaatt taagtaccgt
      721 tacttatgag caagtattgt ctatttttaa tagttatcta ttatttaacg ggaggaaata
      781 attctatgag tcgctttttt aaatttggaa agttacacgt tactaaaggg aatggagata
      841 aattattaga tatactactg acagcttcca agaagctaaa gaggtcccta gcgcctacga
      901 ggaatttgta tcgataaggg gtacaaattc ccactaagcg ctcgggaccc cttgtaggaa
      961 aatgtcctaa gtgtggcaac aatattgtat t
//
LOCUS       DAXLPQ010000239          991 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.180, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000239 DAXLPQ010000000
VERSION     DAXLPQ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.180"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UO_002986"
     CDS             44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UO_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3658883.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKYA
                     KVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          357 a          172 c          169 g          293 t
ORIGIN      
        1 ttctgtattt gtttatagat gtaatcactt caggagtgat aacatgaaca aaaatataaa
       61 atattctcaa aactttttaa cgagtgaaaa agtactcaac caaataataa aacaattgaa
      121 tttaaaagaa accgataccg tttacgaaat tggaacaggt aaagggcatt taacgacgaa
      181 actggctaaa ataagtaaac aggtaacgtc tattgaatta gacagtcatc tattcaactt
      241 atcgtcagaa aaattaaaac tgaatactcg tgtcacttta attcaccaag atattctaca
      301 gtttcaattc cctaacaaac agaggtataa aattgttggg aatattcctt accatttaag
      361 cacacaaatt attaaaaaag tggtttttga aagccgtgcg tctgacatct atctgattgt
      421 tgaagaagga ttctacaagc gtaccttgga tattcaccga acactagggt tgctcttgca
      481 cactcaagtc tcgattcagc aattgcttaa gctgccagcg gaatgctttc atcctaaacc
      541 aaaagtaaac agtgtcttaa taaaacttac ccgccatacc acagatgttc cagataaata
      601 ttggaagcta tatacgtact ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt
      661 tactaaaaat cagtttcatc aagcaatgaa atacgccaaa gtaaacgatt taagtaccgt
      721 tacttatgag caagtattgt ctatttttaa tagttatcta ttatttaacg ggaggaaata
      781 attctatgag tcgctttttt aaatttggaa agttacacgt tactaaaggg aatggagata
      841 aattattaga tatactactg acagcttcca agaagctaaa gaggtcccta gcgcctacga
      901 ggaatttgta tcgataaggg gtacaaattc ccactaagcg ctcgggaccc cttgtaggaa
      961 aatgtcctaa gtgtggcaac aatattgtat t
//
LOCUS       DAXLPQ010000240          730 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.187, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000240 DAXLPQ010000000
VERSION     DAXLPQ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.187"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            117..665
                     /gene="aac(6')"
                     /locus_tag="ACF3UO_002987"
     CDS             117..665
                     /gene="aac(6')"
                     /locus_tag="ACF3UO_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFD3658884.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          268 a          110 c          166 g          186 t
ORIGIN      
        1 gtaagataaa taatgaaaga atagagatac tgattggtag ctaaagattt ttgagcgaga
       61 acatttcgtt ttttcaaaag gactgttaga ataagcaaga acaaggggga agacgtatga
      121 taatcagtga atttgaccgt aataatccag tattgaaaga tcagctttct gatttactga
      181 gactgacttg gccggaagaa tatggagaca gctcggcaga agaagtagaa gaaatgatga
      241 atccagaacg aatcgcggta gcagcggtag accaagatga gttagtagga tttattggtg
      301 caatccctca atacggtatc acaggttggg aattgcatcc attagttgta gaaagctccc
      361 gacgaaagaa ccaaataggt actcgattag tcaattactt agaaaaagaa gtagcttcca
      421 gaggaggaat cacgatttat ttaggtacgg atgatttaga ccatggaaca acgttaagtc
      481 aaacggacct gtatgagcat acatttgata aagtggcttc catccagaac cttcgtgaac
      541 atccgtatga attctatgaa aaattaggtt ataaaatcgt aggtgtctta ccaaatgcaa
      601 atggctggga caaaccggat atttggatgg caaaaacgat tattcctcga ccaaattctc
      661 aataataaaa agaggttgtg acagaagtaa tcagcttcaa gaaataagaa ggaatttacg
      721 aaaattactt
//
LOCUS       DAXLPQ010000241          649 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.193, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000241 DAXLPQ010000000
VERSION     DAXLPQ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.193"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..439
                     /locus_tag="ACF3UO_002988"
     CDS             <1..439
                     /locus_tag="ACF3UO_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFD3658885.1"
                     /translation="WPFYFYTIIRTLSVFESHASDIYLIVEEGFYKRTLDIHRTLGLL
                     LHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREY
                     RQLFTKNQFHQAMKHAKVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          210 a          122 c          119 g          198 t
ORIGIN      
        1 atggcctttt tacttttaca caattatacg gactttatcg gtttttgaaa gccatgcgtc
       61 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
      121 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
      181 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
      241 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
      301 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
      361 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
      421 atttaacggg aggaaataat tctatgagtc gcttttttaa atttggaaag ttacacgtta
      481 ctaaagggaa tggagataaa ttattagata tactactgac agcttccaag aagctaaaga
      541 ggtccctagc gcctacgagg aatttgtatc gataaggggt acaaattccc actaagcgct
      601 cgggacccct tgtaggaaaa tgtcctaagt gtggcaacaa tattgtatt
//
LOCUS       DAXLPQ010000242          649 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2391
            SAMD00565605-rid20744853.guided.194, whole genome shotgun sequence.
ACCESSION   DAXLPQ010000242 DAXLPQ010000000
VERSION     DAXLPQ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565605
            Sequence Read Archive: DRR427991
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054630.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054630.1
            Genome Coverage       :: 161x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:33:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,989
            CDSs (total)                      :: 2,919
            Genes (coding)                    :: 2,820
            CDSs (with protein)               :: 2,820
            Genes (RNA)                       :: 70
            rRNAs                             :: 1, 3, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 43 of 99
            Pseudo Genes (incomplete)         :: 50 of 99
            Pseudo Genes (internal stop)      :: 27 of 99
            Pseudo Genes (multiple problems)  :: 18 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565605-rid20744853.guided.194"
                     /strain="JARB-OU2391"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2020-11-17"
                     /collected_by="Hiroshima"
     gene            <1..439
                     /locus_tag="ACF3UO_002989"
     CDS             <1..439
                     /locus_tag="ACF3UO_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFD3658886.1"
                     /translation="WPFYFYTIIRTLSVFESHASDIYLIVEEGFYKRTLDIHRTLGLL
                     LHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREY
                     RQLFTKNQFHQAMKYAKVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          209 a          121 c          120 g          199 t
ORIGIN      
        1 atggcctttt tacttttaca caattatacg gactttatcg gtttttgaaa gccatgcgtc
       61 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
      121 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
      181 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
      241 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
      301 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaat acgccaaagt
      361 aaacgattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
      421 atttaacggg aggaaataat tctatgagtc gcttttttaa atttggaaag ttacacgtta
      481 ctaaagggaa tggagataaa ttattagata tactactgac agcttccaag aagctaaaga
      541 ggtccctagc gcctacgagg aatttgtatc gataaggggt acaaattccc actaagcgct
      601 cgggacccct tgtaggaaaa tgtcctaagt gtggcaacaa tattgtatt
//
